6zkw A 2.26 BS01 III C 1 Y7 H9 M45 R62 E63 S66 A67 V76 N77 T80 Y84 W97 H99 F116 L124 S143 K146 E152 Q156 Y159 W167 Y171 Y6 H8 M44 R61 E62 S65 A66 V75 N76 T79 Y83 W96 H98 F115 L123 S142 K145 E151 Q155 Y158 W166 Y170 SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKP 6zkw D 2.26 BS01 III C 1 A29 Y37 Q109 A29 Y31 Q95 AQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVTNQAGTALIFGKGTTLSVSSNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSACANAFN 6zkw E 2.26 BS01 III C 1 Y38 R111 Y30 R97 AGVTQTPKFQVLKTGQSMTLQCSQDMNHEYMSWYRQDPGMGLRLIHYSVGAGITDQGEVPNGYNVSRSTTEDFPLRLLSAAPSQTSVYFCASSYSIRGSRGEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 6zkx A 2.17 BS01 III C 1 Y7 H9 M45 Y59 R62 E63 I73 F74 N77 T80 C84 W97 H99 F116 Y123 L124 W133 A139 Q141 I142 S143 K146 E152 H155 Q156 Y159 T163 W167 Y171 Y6 H8 M43 Y57 R60 E61 I71 F72 N75 T78 C82 W95 H97 F114 Y121 L122 W131 A137 Q139 I140 S141 K144 E150 H153 Q154 Y157 T161 W165 Y169 SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGCYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKP 6zkx D 2.17 BS01 III C 1 A29 Y37 Q109 A110 A29 Y31 Q95 A96 AQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVTNQAGTALIFGKGTTLSVSSNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFN 6zkx E 2.17 BS01 III C 1 Y38 R111 Y31 R98 NAGVTQTPKFQVLKTGQSMTLQCSQDMNHEYMSWYRQDPGMGLRLIHYSVGAGITDQGEVPNGYNVSRSTTEDFPLRLLSAAPSQTSVYFCASSYSIRGSRGEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 6zky A 2.65 BS01 III C 1 L5 Y7 H9 M45 R62 E63 T70 I73 V76 N77 W97 H99 F116 K146 C147 E152 H155 Q156 Y159 W167 Y171 L4 Y6 H8 M44 R61 E62 T69 I72 V75 N76 W96 H98 F115 K145 C146 E151 H154 Q155 Y158 W166 Y170 SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKCNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGETQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKP 6zky A 2.65 BS02 QMB C 1 N77 T80 Y84 L124 S143 K146 C147 N76 T79 Y83 L123 S142 K145 C146 SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKCNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGETQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKP 6zky D 2.65 BS01 III C 1 A29 Y37 Q109 A28 Y30 Q94 QEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVTNQAGTALIFGKGTTLSVSSNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFN 6zky E 2.65 BS01 III C 1 Y38 R111 Y31 R98 NAGVTQTPKFQVLKTGQSMTLQCSQDMNHEYMSWYRQDPGMGLRLIHYSVGAGITDQGEVPNGYNVSRSTTEDFPLRLLSAAPSQTSVYFCASSYSIRGSRGEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 6zkz A 2.30 BS01 III C 1 Y7 H9 M45 R62 E63 S66 A67 T70 F74 V76 N77 W97 H99 E152 H155 Q156 Y159 T163 W167 Y171 Y6 H8 M44 R61 E62 S65 A66 T69 F73 V75 N76 W96 H98 E151 H154 Q155 Y158 T162 W166 Y170 SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQCAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKP 6zkz A 2.30 BS02 QM8 A 1 N77 T80 Y84 C116 S143 K146 N76 T79 Y83 C115 S142 K145 SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQCAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKP 6zkz D 2.30 BS01 III C 1 A29 Y37 Q109 A29 Y31 Q95 AQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVTNQAGTALIFGKGTTLSVSSNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDACANAFN 6zkz E 2.30 BS01 III C 1 Y38 R111 Y30 R97 AGVTQTPKFQVLKTGQSMTLQCSQDMNHEYMSWYRQDPGMGLRLIHYSVGAGITDQGEVPNGYNVSRSTTEDFPLRLLSAAPSQTSVYFCASSYSIRGSRGEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 7clk A 2.15 BS01 MG A 1 D241 E283 D310 K335 D241 E283 D310 K335 4.2.1.11 MPIIEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGAEVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALDAAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASIGDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTMISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPR 7clk A 2.15 BS02 2PG A 1 G40 A41 S42 E47 H154 Q162 D241 A243 D310 D311 K335 Q338 R364 S365 G40 A41 S42 E47 H154 Q162 D241 A243 D310 D311 K335 Q338 R364 S365 4.2.1.11 MPIIEQVRAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGAEVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALDAAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASIGDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTMISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPR 7dqx A 3.44 BS01 MCN A 1 G267 S268 F269 G270 R383 V511 G512 Q513 V518 S550 W551 S552 S553 R554 S555 T556 T678 Q682 G745 L746 G747 E748 G242 S243 F244 G245 R358 V486 G487 Q488 V493 S525 W526 S527 S528 R529 S530 T531 T653 Q657 G720 L721 G722 E723 1.5.99.14 NRQAWIGQEVLRREDRRLLTGTATFAGDLGVPGQLHMRIVRSTQAHARIVSIDATEAEKTPGVRMVITSEHTRHLGSVLLEELGYHEIYENIEDFSHPVLAVDKVLYVGQPVVAVLAVDPYLAEDAAELVSIEYEPLPVLLDPEEALTGKVELFPGRGNEGARIKKAYGDIDRAFAEAEHVIRHKYVTNRHSGVPMEPRAVVVQPDPARDTLFIWGDNRRIIAKMLNLPEVNVRMKHVEIGGSFGVKGGVFPENVVAAWAARTLGVPIKWTEDRVEHMTSTSHAREMVHKLELALDAEGRILGMKDEIFHNHGAYFRQAEPLVSDITAGIVFGPYRVPAYDATLHAVFTNKTPVGAYRAPGRYESTFARERIFDLACAEIGLSKTEFRRRNLLTAEDLPWTPGLDIVHEPYHFDSGDVVKHFNEALEAANFSEWLEESKRLRADGRKVGVGLGVLMDKAGLGLFETGGVEVSRAGRVTVKTGGSSVGQGIETVLAQIVAEELQIAPENIDIVHSDTELIPDGVGSWSSRSTVLAGGAARKAALAVVEKARRLASEMLEADPDDLELTAGSFKVKGTDQQISLYEIAAARDPFTARADNDEPGLAADAVYMNNAMNYPYGVTLVQIELDPDTGGHRILRFSTSTEAGRVINPLTTRGQIIGAAVQGIGGALYEEFLYEEDGQPITTSFMDYLLPSAQEMPNVDCFVTEDAKSPDNPFGAKGLGEIGIIAAGAAIASAIDDAIADGVHTDRLPVTPEQIFSRCQGLN 7dqx A 3.44 BS02 MO A 1 F269 G270 F244 G245 1.5.99.14 NRQAWIGQEVLRREDRRLLTGTATFAGDLGVPGQLHMRIVRSTQAHARIVSIDATEAEKTPGVRMVITSEHTRHLGSVLLEELGYHEIYENIEDFSHPVLAVDKVLYVGQPVVAVLAVDPYLAEDAAELVSIEYEPLPVLLDPEEALTGKVELFPGRGNEGARIKKAYGDIDRAFAEAEHVIRHKYVTNRHSGVPMEPRAVVVQPDPARDTLFIWGDNRRIIAKMLNLPEVNVRMKHVEIGGSFGVKGGVFPENVVAAWAARTLGVPIKWTEDRVEHMTSTSHAREMVHKLELALDAEGRILGMKDEIFHNHGAYFRQAEPLVSDITAGIVFGPYRVPAYDATLHAVFTNKTPVGAYRAPGRYESTFARERIFDLACAEIGLSKTEFRRRNLLTAEDLPWTPGLDIVHEPYHFDSGDVVKHFNEALEAANFSEWLEESKRLRADGRKVGVGLGVLMDKAGLGLFETGGVEVSRAGRVTVKTGGSSVGQGIETVLAQIVAEELQIAPENIDIVHSDTELIPDGVGSWSSRSTVLAGGAARKAALAVVEKARRLASEMLEADPDDLELTAGSFKVKGTDQQISLYEIAAARDPFTARADNDEPGLAADAVYMNNAMNYPYGVTLVQIELDPDTGGHRILRFSTSTEAGRVINPLTTRGQIIGAAVQGIGGALYEEFLYEEDGQPITTSFMDYLLPSAQEMPNVDCFVTEDAKSPDNPFGAKGLGEIGIIAAGAAIASAIDDAIADGVHTDRLPVTPEQIFSRCQGLN 7dqx B 3.44 BS01 FAD B 1 K29 I30 I31 A32 G33 G34 Q35 S36 L37 H78 A102 I106 G110 T111 G113 G114 S115 A117 A123 E124 L166 I167 Y193 K29 I30 I31 A32 G33 G34 Q35 S36 L37 H78 A102 I106 G110 T111 G113 G114 S115 A117 A123 E124 L166 I167 Y193 1.5.99.14 MKPPSFDYVVADSVEHALRLLADGGDDAKIIAGGQSLVPLLNFRMSRPSLLVDINRVPGLANIRKSDQTIAIGALTRHAKLTTSKTISQNLPILSEAAAWIAHPQIRNRGTIGGSLAHADAAAELPVVLLALDAYVTAQSLQGERKIPLKELLVSHFVSSILPGELIVEVNVPQLPHGSGAAFDEFSRRHGDYAIGGAASIVTLDEQGKCSRARITVLGGGSTAIRCQEAENILIDSTLSSHDIAAAAHAAVQGLDPVPTVHGSAQYRAQVIRTMVERTLAKALHRA 7dqx C 3.44 BS01 MCN A 1 Q100 C101 C139 Q100 C101 C139 1.5.99.14 MNAFRLTVEVNGVTHATDVEPRRLLADFLRDDLHLRGTRVGCEHGVCGSCTVILDGQPVRSCTVLAVQANNSRIETVESLQKDGQLHPLQRSFSKCHALQCGFCTSGFLMTLKPLYDDEDVTLDATSAREAISGNLCRCTGYQQIVEATVDAFHCRDHND 7dqx C 3.44 BS02 FAD B 1 H44 G45 V46 H44 G45 V46 1.5.99.14 MNAFRLTVEVNGVTHATDVEPRRLLADFLRDDLHLRGTRVGCEHGVCGSCTVILDGQPVRSCTVLAVQANNSRIETVESLQKDGQLHPLQRSFSKCHALQCGFCTSGFLMTLKPLYDDEDVTLDATSAREAISGNLCRCTGYQQIVEATVDAFHCRDHND 7dqx C 3.44 BS03 FES C 1 V40 C42 G45 V46 C47 G48 C50 R60 C62 V40 C42 G45 V46 C47 G48 C50 R60 C62 1.5.99.14 MNAFRLTVEVNGVTHATDVEPRRLLADFLRDDLHLRGTRVGCEHGVCGSCTVILDGQPVRSCTVLAVQANNSRIETVESLQKDGQLHPLQRSFSKCHALQCGFCTSGFLMTLKPLYDDEDVTLDATSAREAISGNLCRCTGYQQIVEATVDAFHCRDHND 7dqx C 3.44 BS04 FES C 2 Q100 C101 C104 C137 R138 C139 Q100 C101 C104 C137 R138 C139 1.5.99.14 MNAFRLTVEVNGVTHATDVEPRRLLADFLRDDLHLRGTRVGCEHGVCGSCTVILDGQPVRSCTVLAVQANNSRIETVESLQKDGQLHPLQRSFSKCHALQCGFCTSGFLMTLKPLYDDEDVTLDATSAREAISGNLCRCTGYQQIVEATVDAFHCRDHND 7dqx E 3.44 BS01 FAD E 1 K29 I30 I31 G33 G34 Q35 S36 L37 H78 I101 A102 I106 G110 T111 G113 G114 S115 A117 A122 A123 E124 L166 I167 Y193 K29 I30 I31 G33 G34 Q35 S36 L37 H78 I101 A102 I106 G110 T111 G113 G114 S115 A117 A122 A123 E124 L166 I167 Y193 1.5.99.14 MKPPSFDYVVADSVEHALRLLADGGDDAKIIAGGQSLVPLLNFRMSRPSLLVDINRVPGLANIRKSDQTIAIGALTRHAKLTTSKTISQNLPILSEAAAWIAHPQIRNRGTIGGSLAHADAAAELPVVLLALDAYVTAQSLQGERKIPLKELLVSHFVSSILPGELIVEVNVPQLPHGSGAAFDEFSRRHGDYAIGGAASLVTLDEQGKCSRARITVLGGGSTAIRCQEAENILIDSTLSSHDIAAAAHAAVQGLDPVPTVHGSAQYRAQVIRTMVERTLAKALHRARPTKES 7dqx F 3.44 BS01 FES F 1 V40 C42 E43 G45 V46 C47 G48 C50 R60 C62 V40 C42 E43 G45 V46 C47 G48 C50 R60 C62 1.5.99.14 MNAFRLTVEVNGVTHATDVEPRRLLADFLRDDLHLRGTRVGCEHGVCGSCTVILDGQPVRSCTVLAVQANNSRIETVESLQKDGQLHPLQRSFSKCHALQCGFCTSGFLMTLKPLYDDEDVTLDATSAREAISGNLCRCTGYQQIVEATVDAFHCRDHND 7dqx F 3.44 BS02 FES F 2 Q100 C101 C104 C137 R138 C139 Q100 C101 C104 C137 R138 C139 1.5.99.14 MNAFRLTVEVNGVTHATDVEPRRLLADFLRDDLHLRGTRVGCEHGVCGSCTVILDGQPVRSCTVLAVQANNSRIETVESLQKDGQLHPLQRSFSKCHALQCGFCTSGFLMTLKPLYDDEDVTLDATSAREAISGNLCRCTGYQQIVEATVDAFHCRDHND 7dqx F 3.44 BS03 MCN D 1 Q100 C101 C139 Q100 C101 C139 1.5.99.14 MNAFRLTVEVNGVTHATDVEPRRLLADFLRDDLHLRGTRVGCEHGVCGSCTVILDGQPVRSCTVLAVQANNSRIETVESLQKDGQLHPLQRSFSKCHALQCGFCTSGFLMTLKPLYDDEDVTLDATSAREAISGNLCRCTGYQQIVEATVDAFHCRDHND 7dqx D 3.44 BS01 MCN D 1 G267 S268 F269 G270 R383 V511 G512 Q513 G514 I515 V518 S550 W551 S552 S553 R554 S555 T556 T678 T679 Q682 G745 L746 G747 E748 G247 S248 F249 G250 R363 V491 G492 Q493 G494 I495 V498 S530 W531 S532 S533 R534 S535 T536 T658 T659 Q662 G725 L726 G727 E728 1.5.99.14 NRQAWIGQEVLRREDRRLLTGTATFAGDLGVPGQLHMRIVRSTQAHARIVSIDATEAEKTPGVRMVITSEHTRHLGSVLLEELGYHEIYENIEDFSHPVLAVDKVLYVGQPVVAVLAVDPYLAEDAAELVSIEYEPLPVLLDPEEALTGKVELFPGRGNEGARIKKAYGDIDRAFAEAEHVIRHKYVTNRHSGVPMEPRAVVVQPDPARDTLFIWGTVHVHDNRRIIAKMLNLPEVNVRMKHVEIGGSFGVKGGVFPENVVAAWAARTLGVPIKWTEDRVEHMTSTSHAREMVHKLELALDAEGRILGMKDEIFHNHGAYFRQAEPLVSDITAGIVFGPYRVPAYDATLHAVFTNKTPVGAYRAPGRYESTFARERIFDLACAEIGLSKTEFRRRNLLTAEDLPWTPGLDIVHEPYHFDSGDVVKHFNEALEAANFSEWLEESKRLRADGRKVGVGLGVLMDKAGLGLFETGGVEVSRAGRVTVKTGGSSVGQGIETVLAQIVAEELQIAPENIDIVHSDTELIPDGVGSWSSRSTVLAGGAARKAALAVVEKARRLASEMLEADPDDLELTAGSFKVKGTDQQISLYEIAAARDPFTARADNDEPGLAADAVYMNNAMNYPYGVTLVQIELDPDTGGHRILRFSTSTEAGRVINPLTTRGQIIGAAVQGIGGALYEEFLYEEDGQPITTSFMDYLLPSAQEMPNVDCFVTEDAKSPDNPFGAKGLGEIGIIAAGAAIASAIDDAIADGVHTDRLPVTPEQIFSRCQGLN 7dqx D 3.44 BS02 MO D 1 F269 G270 F249 G250 1.5.99.14 NRQAWIGQEVLRREDRRLLTGTATFAGDLGVPGQLHMRIVRSTQAHARIVSIDATEAEKTPGVRMVITSEHTRHLGSVLLEELGYHEIYENIEDFSHPVLAVDKVLYVGQPVVAVLAVDPYLAEDAAELVSIEYEPLPVLLDPEEALTGKVELFPGRGNEGARIKKAYGDIDRAFAEAEHVIRHKYVTNRHSGVPMEPRAVVVQPDPARDTLFIWGTVHVHDNRRIIAKMLNLPEVNVRMKHVEIGGSFGVKGGVFPENVVAAWAARTLGVPIKWTEDRVEHMTSTSHAREMVHKLELALDAEGRILGMKDEIFHNHGAYFRQAEPLVSDITAGIVFGPYRVPAYDATLHAVFTNKTPVGAYRAPGRYESTFARERIFDLACAEIGLSKTEFRRRNLLTAEDLPWTPGLDIVHEPYHFDSGDVVKHFNEALEAANFSEWLEESKRLRADGRKVGVGLGVLMDKAGLGLFETGGVEVSRAGRVTVKTGGSSVGQGIETVLAQIVAEELQIAPENIDIVHSDTELIPDGVGSWSSRSTVLAGGAARKAALAVVEKARRLASEMLEADPDDLELTAGSFKVKGTDQQISLYEIAAARDPFTARADNDEPGLAADAVYMNNAMNYPYGVTLVQIELDPDTGGHRILRFSTSTEAGRVINPLTTRGQIIGAAVQGIGGALYEEFLYEEDGQPITTSFMDYLLPSAQEMPNVDCFVTEDAKSPDNPFGAKGLGEIGIIAAGAAIASAIDDAIADGVHTDRLPVTPEQIFSRCQGLN 7duh B 3.75 BS01 MG B 1 R96 L98 R90 L92 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 7duh B 3.75 BS02 MG B 2 E20 K74 D189 D191 D205 E14 K68 D183 D185 D199 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 7duh B 3.75 BS03 MG B 3 R53 Y199 R47 Y193 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 7duh C 3.75 BS01 MG C 1 F128 A129 V130 F127 A128 V129 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 7duh C 3.75 BS02 MG C 2 P114 F186 P113 F185 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 7duh C 3.75 BS03 MG C 3 R11 R179 A180 N181 I182 R10 R178 A179 N180 I181 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 7duh D 3.75 BS01 ZN D 1 C9 C12 L19 C26 C31 C8 C11 L18 C25 C30 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 7duh D 3.75 BS02 MG D 1 W173 R187 W172 R186 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 7duh D 3.75 BS03 MG D 2 A82 S83 K85 G87 T89 A81 S82 K84 G86 T88 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 7duh E 3.75 BS01 MG E 1 E68 P70 E64 P66 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 7duh F 3.75 BS01 MG F 1 R82 D83 V85 R82 D83 V85 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 7duh N 3.75 BS01 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 7duh Q 3.75 BS01 MG Q 1 D13 M15 T18 E49 D12 M14 T17 E48 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYQSLSK 7dul B 3.62 BS01 MG B 1 E20 K74 D189 D191 D205 E14 K68 D183 D185 D199 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 7dul B 3.62 BS02 MG B 2 E50 R53 D198 Y199 E44 R47 D192 Y193 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 7dul C 3.62 BS01 MG C 1 F128 A129 V130 F127 A128 V129 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 7dul C 3.62 BS02 MG C 2 P114 Q118 F186 P113 Q117 F185 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 7dul C 3.62 BS03 MG C 3 R11 R179 A180 N181 I182 R10 R178 A179 N180 I181 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 7dul D 3.62 BS01 ZN D 1 C9 C12 L19 C26 C31 C8 C11 L18 C25 C30 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 7dul D 3.62 BS02 MG D 1 W173 R187 W172 R186 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 7dul D 3.62 BS03 MG D 2 A82 S83 K85 G87 T89 A81 S82 K84 G86 T88 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 7dul E 3.62 BS01 MG E 1 E68 P70 E64 P66 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 7dul F 3.62 BS01 MG F 1 R80 R82 V85 R80 R82 V85 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 7dul N 3.62 BS01 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 7dul Q 3.62 BS01 MG Q 1 D13 M15 E49 D12 M14 E48 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYQSLSK 7dy3 A 1.40 BS01 HEM A 1 M32 T39 Y42 F43 H45 F46 H58 K61 V62 A65 L83 L86 Y87 L91 V93 N97 F98 L101 M32 T39 Y42 F43 H45 F46 H58 K61 V62 A65 L83 L86 Y87 L91 V93 N97 F98 L101 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLYAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 7dy3 B 1.40 BS01 HEM B 1 F41 F42 F45 H63 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 F41 F42 F45 H63 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 7dy3 C 1.40 BS01 HEM C 1 T39 Y42 F43 H45 H58 K61 V62 A65 L83 L86 Y87 L91 V93 N97 F98 L101 L136 T39 Y42 F43 H45 H58 K61 V62 A65 L83 L86 Y87 L91 V93 N97 F98 L101 L136 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLYAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 7dy3 D 1.40 BS01 HEM D 1 F41 F42 H63 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 F41 F42 H63 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 7dy3 E 1.40 BS01 HEM E 1 M32 T39 Y42 F43 F46 H58 K61 V62 A65 L83 L86 Y87 L91 V93 N97 F98 L101 M32 T39 Y42 F43 F46 H58 K61 V62 A65 L83 L86 Y87 L91 V93 N97 F98 L101 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLYAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 7dy3 F 1.40 BS01 HEM F 1 L31 F41 F42 H63 K66 V67 A70 L88 L91 H92 L96 V98 N102 F103 L106 L141 L31 F41 F42 H63 K66 V67 A70 L88 L91 H92 L96 V98 N102 F103 L106 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 7dy3 G 1.40 BS01 HEM G 1 M32 T39 Y42 F43 H45 F46 H58 K61 V62 A65 L83 L86 Y87 L91 V93 N97 F98 L101 L136 M32 T39 Y42 F43 H45 F46 H58 K61 V62 A65 L83 L86 Y87 L91 V93 N97 F98 L101 L136 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLYAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 7dy3 H 1.40 BS01 HEM H 1 F41 F42 H63 K66 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 F41 F42 H63 K66 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 7dy4 A 1.30 BS01 HEM A 1 Y42 F43 H45 F46 Y58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 Y58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGYGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 7dy4 B 1.30 BS01 HEM B 1 F41 F42 H63 V67 A70 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 F41 F42 H63 V67 A70 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 7dy4 C 1.30 BS01 HEM C 1 Y42 F43 H45 F46 Y58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 Y58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGYGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 7dy4 D 1.30 BS01 HEM D 1 F41 F42 F45 H63 K66 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 F41 F42 F45 H63 K66 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 7dy4 E 1.30 BS01 HEM E 1 Y42 F43 F46 Y58 K61 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 F46 Y58 K61 L83 L86 H87 L91 V93 N97 F98 L101 L136 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGYGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 7dy4 F 1.30 BS01 HEM F 1 F41 F42 H63 K66 V67 L88 L91 H92 L96 V98 N102 F103 L106 L141 F41 F42 H63 K66 V67 L88 L91 H92 L96 V98 N102 F103 L106 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 7dy4 G 1.30 BS01 HEM G 1 Y42 F43 H45 F46 Y58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 Y58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGYGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 7dy4 H 1.30 BS01 HEM H 1 F41 F42 F45 H63 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 F41 F42 F45 H63 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 7dy7 B 2.42 BS01 HOU B 1 I54 Y56 N63 Q66 V76 M115 I116 S117 A121 D122 I37 Y39 N46 Q49 V59 M98 I99 S100 A104 D105 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHHHH 7dy7 A 2.42 BS01 HOU B 1 Y56 M115 I116 S117 A121 D122 Y123 K124 R125 Y39 M98 I99 S100 A104 D105 Y106 K107 R108 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHHHH 7dyd D 2.39 BS01 EY3 D 1 G104 T105 S133 G136 T137 G51 T52 S80 G83 T84 TVSWYTGLTQHGKVPLTFPPGQGVPLNANSTPAQNAGYWRLAPRWYFYYTGTGPEAALPFRAVKDGIVWVHEDGATDAPSTFGTRNPNNDSAIVTQFAPGTKLPKNFHIE 7dyg A 2.00 BS01 0WS A 1 Y136 Y181 F189 H192 E194 N202 K210 W212 H280 Y126 Y171 F179 H182 E184 N192 K200 W202 H270 1.14.11.66 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 7dyg A 2.00 BS02 FE A 1 H192 E194 H280 H182 E184 H270 1.14.11.66 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 7dyq A 2.00 BS01 HR0 A 1 Y181 F189 H192 E194 N202 K210 T211 W212 H280 A281 G282 A292 Y171 F179 H182 E184 N192 K200 T201 W202 H270 A271 G272 A282 1.14.11.66 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 7dyq A 2.00 BS02 FE A 1 H192 E194 H280 H182 E184 H270 1.14.11.66 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 7dyy A 1.80 BS01 ZN A 1 D118 C198 H240 D87 C167 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dyy A 1.80 BS02 ZN A 2 H114 H116 H179 H83 H85 H148 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dyy A 1.80 BS03 HQF A 1 F62 Y67 W87 D118 H179 C198 R205 N210 H240 F31 Y36 W56 D87 H148 C167 R174 N179 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dyy B 1.80 BS01 ZN B 1 H114 H116 H179 H83 H85 H148 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dyy B 1.80 BS02 ZN B 2 D118 C198 H240 D87 C167 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dyy B 1.80 BS03 HQF B 1 F62 Y67 W87 H179 C198 R205 H240 F31 Y36 W56 H148 C167 R174 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dyz A 1.90 BS01 ZN A 1 D118 C198 H240 D87 C167 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dyz A 1.90 BS02 ZN A 2 H114 H116 H179 H83 H85 H148 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dyz A 1.90 BS03 HQR A 1 F62 Y67 W87 D118 H179 C198 R205 H240 F31 Y36 W56 D87 H148 C167 R174 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz0 A 3.23 BS01 ZN A 1 H114 H116 H179 C198 H83 H85 H148 C167 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz0 A 3.23 BS02 ZN A 2 D118 R119 C198 H240 D87 R88 C167 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz0 A 3.23 BS03 HQ0 A 1 F62 Y67 W87 D118 H179 C198 R205 H240 F31 Y36 W56 D87 H148 C167 R174 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz0 B 3.23 BS01 ZN B 1 H114 H116 H179 H83 H85 H148 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz0 B 3.23 BS02 ZN B 2 D118 C198 H240 D87 C167 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz0 B 3.23 BS03 HQ0 B 1 F62 Y67 W87 D118 H179 C198 R205 H240 F31 Y36 W56 D87 H148 C167 R174 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz1 A 2.71 BS01 ZN A 1 H114 H116 H179 H83 H85 H148 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz1 A 2.71 BS02 ZN A 2 D118 C198 H240 D87 C167 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz1 A 2.71 BS03 HQ3 A 1 Y67 W87 D118 H179 C198 R205 H240 Y36 W56 D87 H148 C167 R174 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz1 B 2.71 BS01 ZN B 1 H114 H116 H179 H83 H85 H148 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz1 B 2.71 BS02 ZN B 2 D118 C198 H240 D87 C167 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dz1 B 2.71 BS03 HQ3 B 1 Y67 W87 D118 H179 C198 R205 N210 H240 Y36 W56 D87 H148 C167 R174 N179 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 7dzm A 2.25 BS01 III C 1 Y9 R64 N65 I68 Y69 Q72 T75 E78 S79 N82 L83 Y86 L97 Y101 N116 Y118 S145 K148 L149 Q157 L158 Y161 W169 Y173 Y8 R63 N64 I67 Y68 Q71 T74 E77 S78 N81 L82 Y85 L96 Y100 N115 Y117 S144 K147 L148 Q156 L157 Y160 W168 Y172 GGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQISQRKLEAARVAEQLRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWTAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPS 7dzm D 2.25 BS01 III C 1 N51 N52 I56 N49 N50 I54 AGVIQSPRHEVTEMGQEVTLRCKPISGHNSLFWYRQTMMRGLELLIYFNNNVPIDDSGMPEDRFSAKMPNASFSTLKIQPSEPRDSAVYFCASSLGIDAIYFGEGSWLTVVEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 7dzm E 2.25 BS01 III C 1 N96 N97 A98 N94 N95 A96 DAKTTQPPSMDCAEGRAANLPCNHSTISGNEYVYWYRQIHSQGPQYIIHGLKNNETNEMASLIITEDRKSSTLILPHATLRDTAVYYCIVRGLNNAGNMLTFGGGTRLMVKPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP 7dzn A 2.63 BS01 III C 1 Y9 R64 N65 I68 Y69 Q72 T75 E78 S79 N82 Y86 Y101 N116 T145 W149 V154 Q157 Y161 T165 W169 Y173 Y7 R62 N63 I66 Y67 Q70 T73 E76 S77 N80 Y84 Y99 N114 T143 W147 V152 Q155 Y159 T163 W167 Y171 GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAARVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPS 7dzn D 2.63 BS01 III C 1 N51 N52 N49 N50 AGVIQSPRHEVTEMGQEVTLRCKPISGHNSLFWYRQTMMRGLELLIYFNNNVPIDDSGMPEDRFSAKMPNASFSTLKIQPSEPRDSAVYFCASSLGIDAIYFGEGSWLTVVEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 7dzn E 2.63 BS01 III C 1 N96 N97 A98 N94 N95 A96 DAKTTQPPSMDCAEGRAANLPCNHSTISGNEYVYWYRQIHSQGPQYIIHGLKNNETNEMASLIITEDRKSSTLILPHATLRDTAVYYCIVRGLNNAGNMLTFGGGTRLMVKPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 7ea4 A 1.95 BS01 CA A 1 N185 E189 D354 E356 D357 G487 N150 E154 D292 E294 D295 G425 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGETLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWQSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7ea4 B 1.95 BS01 CA B 1 N185 E189 D354 E356 D357 G487 N150 E154 D291 E293 D294 G424 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGETLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7ebt A 1.51 BS01 GSH A 1 S12 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S12 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVMK 7ebt A 1.51 BS02 CA A 1 E46 D47 E46 D47 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVMK 7ebt A 1.51 BS03 CA A 2 R37 E40 R37 E40 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVMK 7ebt B 1.51 BS01 GSH B 1 S12 P14 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S15 P17 H46 H58 A59 V60 P61 D72 S73 H74 N109 F113 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVMK 7ebt B 1.51 BS02 CA B 1 E46 D47 E49 D50 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVMK 7ebt C 1.51 BS01 GSH C 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S14 P15 P16 L40 H45 H57 A58 V59 P60 D71 S72 H73 N108 F112 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebt D 1.51 BS01 GSH D 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S14 P15 P16 L40 H45 H57 A58 V59 P60 D71 S72 H73 N108 F112 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebt D 1.51 BS02 CA D 1 E40 E42 E42 E44 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebt D 1.51 BS03 CA D 2 E46 D47 E48 D49 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu A 1.95 BS01 GSH A 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu A 1.95 BS02 ZF1 A 1 I11 P13 L38 F39 H43 E113 M117 R118 I121 T171 I11 P13 L38 F39 H43 E113 M117 R118 I121 T171 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu A 1.95 BS03 CA A 1 E46 D47 E46 D47 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu A 1.95 BS04 CA A 2 K3 E32 K3 E32 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu B 1.95 BS01 GSH B 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S15 P16 P17 L41 H46 H58 A59 V60 P61 D72 S73 H74 N109 F113 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu B 1.95 BS02 ZF1 B 1 I11 P13 L38 H43 E113 M117 R118 T171 I14 P16 L41 H46 E116 M120 R121 T174 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu B 1.95 BS03 CA B 1 E46 D47 E49 D50 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu C 1.95 BS01 GSH C 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S11 P12 P13 L37 H42 H54 A55 V56 P57 D68 S69 H70 N103 F107 SKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu C 1.95 BS02 ZF1 C 1 P13 L38 F39 H43 E113 R118 I121 T171 P12 L37 F38 H42 E110 R115 I118 T168 SKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebu D 1.95 BS01 GSH D 1 S12 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S14 P16 L40 H45 H57 A58 V59 P60 D71 S72 H73 N108 F112 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAV 7ebu D 1.95 BS02 ZF1 D 1 I11 P13 L38 R41 H43 E113 M117 R118 I121 T171 I13 P15 L40 R43 H45 E115 M119 R120 I123 T173 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAV 7ebu D 1.95 BS03 CA D 1 R37 E40 E42 R39 E42 E44 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAV 7ebu D 1.95 BS04 CA D 2 E46 D47 E48 D49 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAV 7ebv A 1.50 BS01 GSH A 1 S12 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S12 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv A 1.50 BS02 LU2 A 1 P13 L38 F39 E113 S114 R118 T171 L210 P13 L38 F39 E113 S114 R118 T170 L209 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv A 1.50 BS03 CA A 1 R37 E40 R37 E40 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv A 1.50 BS04 CA A 2 E46 D47 E46 D47 MSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv B 1.50 BS01 GSH B 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S15 P16 P17 L41 H46 H58 A59 V60 P61 D72 S73 H74 N109 F113 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv B 1.50 BS02 LU2 B 1 P13 L38 F39 E113 S114 M117 T171 L210 P16 L41 F42 E116 S117 M120 T174 L213 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv B 1.50 BS03 CA B 1 E46 D47 E49 D50 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv C 1.50 BS01 GSH C 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S13 P14 P15 L39 H44 H56 A57 V58 P59 D70 S71 H72 N104 F108 MMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv C 1.50 BS02 LU2 C 1 I11 P13 L38 F39 H43 E113 S114 R118 T171 L210 I12 P14 L39 F40 H44 E111 S112 R116 T169 L208 MMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv D 1.50 BS01 GSH D 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 S15 P16 P17 L41 H46 H58 A59 V60 P61 D72 S73 H74 N109 F113 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv D 1.50 BS02 LU2 D 1 P13 L38 F39 R41 H43 E113 S114 I121 T171 P16 L41 F42 R44 H46 E116 S117 I124 T174 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebv D 1.50 BS03 CA D 1 E40 E42 E43 E45 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebw A 1.94 BS01 GSH A 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 R118 S13 P14 P15 L39 H44 H56 A57 V58 P59 D70 S71 H72 N107 F111 R119 MMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebw A 1.94 BS02 674 A 1 I11 P13 L38 F39 H43 E113 S114 M117 R118 I121 T171 L210 I12 P14 L39 F40 H44 E114 S115 M118 R119 I122 T172 L211 MMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebw A 1.94 BS03 CA A 1 E46 D47 E47 D48 MMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebw B 1.94 BS01 GSH B 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 R118 S15 P16 P17 L41 H46 H58 A59 V60 P61 D72 S73 H74 N109 F113 R121 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebw B 1.94 BS02 674 B 1 I11 P13 L38 F39 H43 E113 S114 M117 R118 I121 T171 I14 P16 L41 F42 H46 E116 S117 M120 R121 I124 T174 VHMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebw C 1.94 BS01 GSH C 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 R118 S10 P11 P12 L36 H41 H53 A54 V55 P56 D67 S68 H69 N104 F108 R116 KPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebw C 1.94 BS02 674 C 1 I11 P13 L38 F39 H43 E113 S114 M117 R118 I121 T171 L210 I9 P11 L36 F37 H41 E111 S112 M115 R116 I119 T169 L208 KPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAVM 7ebw D 1.94 BS01 GSH D 1 S12 P13 P14 L38 H43 H55 A56 V57 P58 D69 S70 H71 N106 F110 R118 S14 P15 P16 L40 H45 H57 A58 V59 P60 D71 S72 H73 N108 F112 R120 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAV 7ebw D 1.94 BS02 674 D 1 I11 P13 L38 R41 H43 E113 S114 M117 R118 I121 T171 L210 I13 P15 L40 R43 H45 E115 S116 M119 R120 I123 T173 L212 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAV 7ebw D 1.94 BS03 CA D 1 E46 D47 E48 D49 HMMSKPVLYYDDISPPVRGVLLTVAALGIKDQVELKLVRLFEREHLLEDFVKLNPLHAVPVLKHDDLVLTDSHAIIMYLCDIFGQDGDFSLKDPKQRARVHNRLCFNNAVLFQRESIVMRGLINRSIVTLEDHHLKPVQEAYDCLEVYLTNSKFVACDQLTVADFPIVACMSTVGMVCPLSTSRWPKTAAWFETMKQLPYYQQANQVGVDKLKERLHAV 7eby A 2.00 BS01 CO3 A 1 S282 R305 R313 L348 Y433 E460 S219 R242 R250 L285 Y370 E397 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby A 2.00 BS02 CO3 A 2 H304 Y352 H241 Y289 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby A 2.00 BS03 CO3 A 3 S282 H304 R350 N523 S219 H241 R287 N460 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby A 2.00 BS04 CA A 1 N165 E169 D354 E356 D357 R482 G487 N150 E154 D291 E293 D294 R419 G424 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby B 2.00 BS01 CO3 B 1 S282 R305 R313 L348 Y433 E460 S219 R242 R250 L285 Y370 E397 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby B 2.00 BS02 CO3 B 2 S282 H304 R350 N523 S219 H241 R287 N460 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby B 2.00 BS03 CA B 1 N165 E169 D354 E356 D357 R482 G487 N150 E154 D291 E293 D294 R419 G424 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby C 2.00 BS01 CO3 C 1 S282 H304 R350 N523 S220 H242 R288 N461 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby C 2.00 BS02 CO3 C 2 S282 R305 R313 L348 Y433 E460 S220 R243 R251 L286 Y371 E398 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby C 2.00 BS03 CO3 C 3 H304 Y352 S543 H242 Y290 S481 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby C 2.00 BS04 CA C 1 N165 E169 D354 E356 D357 R482 G487 N151 E155 D292 E294 D295 R420 G425 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby D 2.00 BS01 CO3 D 1 S282 H304 R350 N523 S220 H242 R288 N461 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby D 2.00 BS02 CO3 D 2 H304 Y352 S543 H242 Y290 S481 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby D 2.00 BS03 CO3 D 3 S282 R305 R313 L348 Y433 E460 S220 R243 R251 L286 Y371 E398 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby D 2.00 BS04 CA D 1 N165 E169 D354 E356 D357 R482 G487 N151 E155 D292 E294 D295 R420 G425 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby E 2.00 BS01 CO3 E 1 L162 S282 H304 R350 N523 L148 S220 H242 R288 N461 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby E 2.00 BS02 CO3 E 2 S282 R305 R313 L348 Y433 E460 S220 R243 R251 L286 Y371 E398 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby E 2.00 BS03 CA E 1 N165 E169 D354 E356 D357 R482 G487 N151 E155 D292 E294 D295 R420 G425 PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby F 2.00 BS01 CO3 F 1 S282 H304 R350 N523 S219 H241 R287 N460 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby F 2.00 BS02 CO3 F 2 H304 Y352 H241 Y289 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby F 2.00 BS03 CO3 F 3 S282 R305 R313 L348 Y433 E460 S219 R242 R250 L285 Y370 E397 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7eby F 2.00 BS04 CA F 1 N165 E169 D354 E356 D357 R482 G487 N150 E154 D291 E293 D294 R419 G424 TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQIDLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAEAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLNFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAALKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLRYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYETDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADDASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQVYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYNPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSLRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGWDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAVLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFRHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMVLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVERAAEKRIELTPR 7ejl A 1.89 BS01 III C 1 Y7 M45 E63 K66 V67 H70 T73 E76 N77 I80 Y84 M97 F99 Y123 T143 W147 Q155 Q156 Y159 T163 G167 Y171 Y7 M45 E63 K66 V67 H70 T73 E76 N77 I80 Y84 M97 F99 Y123 T143 W147 Q155 Q156 Y159 T163 G167 Y171 34857854 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 7ejm A 1.71 BS01 III C 1 Y7 M45 E63 K66 V67 H70 T73 N77 I80 Y84 M97 F99 T143 K146 W147 A150 V152 Y159 T163 Y171 Y7 M45 E63 K66 V67 H70 T73 N77 I80 Y84 M97 F99 T143 K146 W147 A150 V152 Y159 T163 Y171 34857854 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 7ejn A 2.11 BS01 III C 1 Y7 M45 E62 E63 K66 V67 H70 T73 E76 N77 I80 Y84 F99 T143 K146 W147 Q155 Q156 Y159 T163 Y171 Y7 M45 E62 E63 K66 V67 H70 T73 E76 N77 I80 Y84 F99 T143 K146 W147 Q155 Q156 Y159 T163 Y171 34857854 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 7ewu B 2.11 BS01 MN B 1 H34 N52 D79 H32 N50 D77 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDEEFLMMIA 7ewu B 2.11 BS02 MN B 2 H34 D79 D92 Y93 K94 H32 D77 D90 Y91 K92 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDEEFLMMIA 7ewu C 2.11 BS01 MN C 1 N52 D79 N50 D77 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDEEFLMMIA 7ewu C 2.11 BS02 MN C 2 H34 D79 D92 Y93 K94 H32 D77 D90 Y91 K92 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDEEFLMMIA 7ewu D 2.11 BS01 MN D 1 H34 N52 D79 H32 N50 D77 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDEEFLMM 7ewu D 2.11 BS02 MN D 2 H34 D79 D92 Y93 K94 H32 D77 D90 Y91 K92 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDEEFLMM 7ewv A 2.61 BS01 MN A 1 N52 D79 N51 D78 2.7.7.48 EDPMYEQFLQRIQAVRTATVAKDISADILEARADYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFAD 7ewv B 2.61 BS01 MN B 1 N51 N52 D79 N49 N50 D77 2.7.7.48 MEDPMYEQFLQRIQAVRTVAKDISADILEARADYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDE 7eww A 2.34 BS01 MN A 1 H34 D79 D92 Y93 K94 H32 D77 D90 Y91 K92 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNAVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDE 7eww B 2.34 BS01 MN B 1 H34 D79 D92 Y93 K94 H32 D77 D90 Y91 K92 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNAVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFA 7ewx A 1.95 BS01 MN A 1 H34 D79 D92 Y93 H32 D77 D90 Y91 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTADNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKF 7ewx B 1.95 BS01 MN B 1 H34 D79 Y93 K94 H34 D79 Y93 K94 2.7.7.48 MEDPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTADNYIWTGDMLLILDYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDEEFLMMIA 7ewz A 2.05 BS01 MN A 1 H34 N52 D79 H33 N51 D78 2.7.7.48 EDPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILAYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFA 7ewz B 2.05 BS01 MN B 1 H34 N51 N52 D79 H33 N50 N51 D78 2.7.7.48 EDPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILAYKVSVGHDSTEVTYKKYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADD 7ex0 A 2.07 BS01 MN A 1 H34 N52 D79 H34 N52 D79 2.7.7.48 MEDPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKAYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDEEFLMMIA 7ex0 A 2.07 BS02 MN A 2 H34 D79 D92 Y93 K94 H34 D79 D92 Y93 K94 2.7.7.48 MEDPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKAYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKFADDEEFLMMIA 7ex0 B 2.07 BS01 MN B 1 N52 T77 D79 N50 T75 D77 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKAYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKF 7ex0 B 2.07 BS02 MN B 2 H34 D79 D92 Y93 K94 H32 D77 D90 Y91 K92 2.7.7.48 DPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDNYIWTGDMLLILDYKVSVGHDSTEVTYKAYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFARFFELRKMLLDKF 7f8j A 3.60 BS01 LBN A 1 V11 L17 A33 M37 C40 I41 L45 L287 Y293 V10 L16 A32 M36 C39 I40 L44 L251 Y257 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j A 3.60 BS02 LBN A 2 F235 L237 Q274 V278 L281 V282 V285 L286 F199 L201 Q238 V242 L245 V246 V249 L250 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j A 3.60 BS03 LBN A 3 L122 F126 K212 S215 L219 L121 F125 K176 S179 L183 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j A 3.60 BS04 LBN A 4 N100 L101 W104 Y111 I112 N99 L100 W103 Y110 I111 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j A 3.60 BS05 LBN A 5 K91 W104 L115 K90 W103 L114 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j A 3.60 BS06 LBN B 1 L122 L125 F129 L121 L124 F128 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j A 3.60 BS07 LBN G 1 L52 I279 L51 I243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j A 3.60 BS08 LBN G 2 L275 V278 L239 V242 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j B 3.60 BS01 LBN A 6 L52 I279 L51 I243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j B 3.60 BS02 LBN A 7 L275 V278 L239 V242 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j B 3.60 BS03 LBN B 1 V11 L17 A33 M37 C40 I41 L45 L287 Y293 V10 L16 A32 M36 C39 I40 L44 L251 Y257 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j B 3.60 BS04 LBN B 2 F235 L237 Q274 V278 L281 V282 V285 L286 F199 L201 Q238 V242 L245 V246 V249 L250 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j B 3.60 BS05 LBN B 3 L122 F126 K212 S215 L219 L121 F125 K176 S179 L183 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j B 3.60 BS06 LBN B 4 L101 W104 Y111 I112 L115 L100 W103 Y110 I111 L114 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j B 3.60 BS07 LBN B 5 K91 L115 K90 L114 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j B 3.60 BS08 LBN D 1 L122 L125 F129 L121 L124 F128 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j C 3.60 BS01 LBN C 1 V11 L17 A33 M37 C40 I41 L45 L287 Y293 V10 L16 A32 M36 C39 I40 L44 L251 Y257 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j C 3.60 BS02 LBN C 2 F235 L237 Q274 V278 L281 V282 V285 L286 F199 L201 Q238 V242 L245 V246 V249 L250 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j C 3.60 BS03 LBN C 3 L122 F126 K212 S215 L219 L121 F125 K176 S179 L183 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j C 3.60 BS04 LBN C 4 L101 W104 Y111 I112 L100 W103 Y110 I111 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j C 3.60 BS05 LBN D 2 L52 I279 L51 I243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j C 3.60 BS06 LBN D 3 L275 V278 L239 V242 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j C 3.60 BS07 LBN E 1 L122 L125 F129 L121 L124 F128 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j D 3.60 BS01 LBN B 6 L52 I279 L51 I243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j D 3.60 BS02 LBN B 7 L275 V278 L239 V242 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j D 3.60 BS03 LBN C 1 L125 F129 L124 F128 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j D 3.60 BS04 LBN D 4 L122 F126 S215 L219 L121 F125 S179 L183 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j D 3.60 BS05 LBN D 5 L101 W104 Y111 I112 L100 W103 Y110 I111 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j D 3.60 BS06 LBN D 1 V11 L17 A33 M37 C40 I41 L45 L287 Y293 V10 L16 A32 M36 C39 I40 L44 L251 Y257 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j D 3.60 BS07 LBN D 6 F235 L237 Q274 V278 L281 V282 V285 L286 F199 L201 Q238 V242 L245 V246 V249 L250 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j E 3.60 BS01 LBN C 5 L52 I279 L51 I243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j E 3.60 BS02 LBN C 6 L275 V278 L239 V242 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j E 3.60 BS03 LBN E 1 V11 L17 A33 M37 C40 I41 L45 L287 Y293 V10 L16 A32 M36 C39 I40 L44 L251 Y257 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j E 3.60 BS04 LBN E 2 F235 L237 Q274 V278 L281 V282 V285 L286 F199 L201 Q238 V242 L245 V246 V249 L250 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j E 3.60 BS05 LBN E 3 L122 F126 I211 K212 S215 L219 L121 F125 I175 K176 S179 L183 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j E 3.60 BS06 LBN E 4 L101 W104 Y111 I112 L100 W103 Y110 I111 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j E 3.60 BS07 LBN E 5 K91 L115 K90 L114 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j E 3.60 BS08 LBN F 1 L122 L125 F129 L121 L124 F128 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j F 3.60 BS01 LBN E 6 L52 I279 L51 I243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j F 3.60 BS02 LBN E 7 L275 V278 L239 V242 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j F 3.60 BS03 LBN F 1 V11 L17 A33 M37 C40 I41 L45 L287 Y293 V10 L16 A32 M36 C39 I40 L44 L251 Y257 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j F 3.60 BS04 LBN F 2 F235 L237 Q274 V278 L281 V282 V285 L286 F199 L201 Q238 V242 L245 V246 V249 L250 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j F 3.60 BS05 LBN F 3 L122 F126 K212 S215 L219 L121 F125 K176 S179 L183 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j F 3.60 BS06 LBN F 4 N100 L101 W104 Y111 I112 N99 L100 W103 Y110 I111 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j F 3.60 BS07 LBN F 5 K91 L115 K90 L114 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j F 3.60 BS08 LBN G 3 L122 L125 F129 L121 L124 F128 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j G 3.60 BS01 LBN A 1 L122 L125 F129 L121 L124 F128 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j G 3.60 BS02 LBN F 6 L52 I279 L51 I243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j G 3.60 BS03 LBN F 7 L275 V278 L239 V242 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j G 3.60 BS04 LBN G 4 L122 F126 I211 K212 S215 L219 L121 F125 I175 K176 S179 L183 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j G 3.60 BS05 LBN G 1 L101 W104 Y111 I112 L115 L100 W103 Y110 I111 L114 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j G 3.60 BS06 LBN G 5 K91 L115 K90 L114 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j G 3.60 BS07 LBN G 6 V11 L17 A33 M37 C40 I41 L45 L287 Y293 V10 L16 A32 M36 C39 I40 L44 L251 Y257 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8j G 3.60 BS08 LBN G 7 F235 L237 Q274 V278 L281 V282 V285 L286 F199 L201 Q238 V242 L245 V246 V249 L250 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n A 3.40 BS01 LBN A 1 V34 M37 P289 V292 Y293 R300 K302 E336 E337 V22 M25 P244 V247 Y248 R255 K257 E289 E290 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n A 3.40 BS02 LBN A 2 M37 Y293 F299 Q301 M25 Y248 F254 Q256 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n A 3.40 BS03 LBN A 3 E31 T39 G44 L47 L48 Y121 E19 T27 G32 L35 L36 Y107 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n A 3.40 BS04 LBN A 4 L275 V278 I279 V282 L230 V233 I234 V237 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n A 3.40 BS05 LBN A 5 F235 S239 F190 S194 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n A 3.40 BS06 LBN B 1 C40 I41 L45 I279 V283 L286 L287 P289 V290 C28 I29 L33 I234 V238 L241 L242 P244 V245 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n A 3.40 BS07 LBN G 1 L115 I118 L119 L122 L125 L101 I104 L105 L108 L111 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n B 3.40 BS01 LBN A 6 F126 I211 K212 S215 L219 F112 I166 K167 S170 L174 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n B 3.40 BS02 LBN B 1 L115 I118 L119 L122 L125 L101 I104 L105 L108 L111 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n B 3.40 BS03 LBN B 2 V34 M37 P289 V292 Y293 R300 K302 E336 E337 V22 M25 P244 V247 Y248 R255 K257 E289 E290 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n B 3.40 BS04 LBN B 3 M37 Y293 F299 Q301 M25 Y248 F254 Q256 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n B 3.40 BS05 LBN B 4 E31 T39 G44 L47 L48 Y121 E19 T27 G32 L35 L36 Y107 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n B 3.40 BS06 LBN B 5 L275 V278 I279 V282 L230 V233 I234 V237 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n B 3.40 BS07 LBN B 6 F235 S239 F190 S194 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n B 3.40 BS08 LBN C 1 C40 I41 L45 I279 V283 L286 L287 P289 V290 C28 I29 L33 I234 V238 L241 L242 P244 V245 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n C 3.40 BS01 LBN B 7 L122 F126 K212 S215 L219 L108 F112 K167 S170 L174 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n C 3.40 BS02 LBN B 8 Q89 K91 Q77 K79 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n C 3.40 BS03 LBN C 1 L115 I118 L119 L122 L101 I104 L105 L108 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n C 3.40 BS04 LBN C 2 V34 M37 P289 V292 Y293 R300 K302 E336 E337 V22 M25 P244 V247 Y248 R255 K257 E289 E290 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n C 3.40 BS05 LBN C 3 M37 Y293 F299 Q301 M25 Y248 F254 Q256 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n C 3.40 BS06 LBN C 4 E31 T39 G44 L47 L48 Y121 E19 T27 G32 L35 L36 Y107 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n C 3.40 BS07 LBN C 5 F235 S239 F190 S194 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n C 3.40 BS08 LBN D 1 C40 I41 L45 I279 V283 L286 L287 P289 V290 C28 I29 L33 I234 V238 L241 L242 P244 V245 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n C 3.40 BS09 LBN D 2 L275 V278 I279 V282 L230 V233 I234 V237 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n D 3.40 BS01 LBN C 6 L122 F126 K212 S215 L219 L108 F112 K167 S170 L174 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n D 3.40 BS02 LBN D 1 L115 I118 L119 L122 L101 I104 L105 L108 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n D 3.40 BS03 LBN D 3 V34 M37 P289 V292 Y293 R300 K302 E336 E337 V22 M25 P244 V247 Y248 R255 K257 E289 E290 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n D 3.40 BS04 LBN D 4 E31 T39 G44 L47 L48 Y121 E19 T27 G32 L35 L36 Y107 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n D 3.40 BS05 LBN D 5 F235 S239 F190 S194 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n D 3.40 BS06 LBN E 1 M37 Y293 F299 Q301 M25 Y248 F254 Q256 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n D 3.40 BS07 LBN E 2 C40 I41 L45 I279 V283 L286 L287 P289 V290 C28 I29 L33 I234 V238 L241 L242 P244 V245 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n D 3.40 BS08 LBN E 3 L275 V278 I279 V282 L230 V233 I234 V237 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS01 LBN D 6 Q89 K91 Q77 K79 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS02 LBN E 1 L122 F126 K212 S215 L219 L108 F112 K167 S170 L174 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS03 LBN E 4 L115 I118 L119 L122 L101 I104 L105 L108 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS04 LBN E 5 Q89 W104 Q77 W90 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS05 LBN E 6 V34 M37 P289 V292 Y293 R300 K302 E336 E337 V22 M25 P244 V247 Y248 R255 K257 E289 E290 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS06 LBN E 7 M37 Y293 F299 Q301 M25 Y248 F254 Q256 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS07 LBN E 8 E31 T39 G44 L47 L48 Y121 E19 T27 G32 L35 L36 Y107 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS08 LBN E 9 L275 V278 I279 V282 L230 V233 I234 V237 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS09 LBN E 10 F235 S239 F190 S194 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n E 3.40 BS10 LBN F 1 C40 I41 L45 I279 V283 L286 L287 P289 V290 C28 I29 L33 I234 V238 L241 L242 P244 V245 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n F 3.40 BS01 LBN E 11 F126 I211 K212 S215 L219 F112 I166 K167 S170 L174 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n F 3.40 BS02 LBN E 12 Q89 K91 Q77 K79 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n F 3.40 BS03 LBN F 1 L115 I118 L119 L122 L101 I104 L105 L108 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n F 3.40 BS04 LBN F 2 V34 M37 P289 V292 Y293 R300 K302 E336 E337 V22 M25 P244 V247 Y248 R255 K257 E289 E290 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n F 3.40 BS05 LBN F 3 M37 Y293 F299 Q301 M25 Y248 F254 Q256 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n F 3.40 BS06 LBN F 4 E31 T39 G44 L47 L48 Y121 E19 T27 G32 L35 L36 Y107 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n F 3.40 BS07 LBN F 5 L275 V278 I279 V282 L230 V233 I234 V237 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n F 3.40 BS08 LBN F 6 F235 S239 F190 S194 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n F 3.40 BS09 LBN G 2 C40 I41 L45 I279 V283 L286 L287 P289 V290 C28 I29 L33 I234 V238 L241 L242 P244 V245 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n G 3.40 BS01 LBN F 7 F126 I211 K212 S215 L219 F112 I166 K167 S170 L174 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n G 3.40 BS02 LBN F 8 Q89 K91 Q77 K79 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n G 3.40 BS03 LBN G 3 L115 I118 L119 L122 L125 L101 I104 L105 L108 L111 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n G 3.40 BS04 LBN G 4 V34 M37 P289 V292 Y293 R300 K302 E336 E337 V22 M25 P244 V247 Y248 R255 K257 E289 E290 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n G 3.40 BS05 LBN G 5 M37 Y293 F299 Q301 M25 Y248 F254 Q256 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n G 3.40 BS06 LBN G 1 C40 I41 L45 I279 V283 L286 L287 P289 V290 C28 I29 L33 I234 V238 L241 L242 P244 V245 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n G 3.40 BS07 LBN G 6 E31 T39 G44 L47 L48 Y121 E19 T27 G32 L35 L36 Y107 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n G 3.40 BS08 LBN G 7 L275 V278 I279 V282 L230 V233 I234 V237 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8n G 3.40 BS09 LBN G 8 F235 S239 F190 S194 SDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSAKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKS 7f8o A 3.60 BS01 LBN A 1 V34 P289 Y293 R300 V33 P250 Y254 R261 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o A 3.60 BS02 LBN A 2 K91 G99 L101 W104 Y111 I112 L115 K90 G96 L98 W101 Y108 I109 L112 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o A 3.60 BS03 LBN A 3 F235 L237 Q274 L275 V282 F196 L198 Q235 L236 V243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o B 3.60 BS01 LBN B 1 V34 P289 Y293 R300 V33 P250 Y254 R261 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o B 3.60 BS02 LBN B 2 K91 G99 L101 W104 Y111 I112 L115 K90 G96 L98 W101 Y108 I109 L112 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o B 3.60 BS03 LBN B 3 F235 L237 Q274 L275 V282 F196 L198 Q235 L236 V243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o C 3.60 BS01 LBN B 4 L275 I279 L236 I240 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o C 3.60 BS02 LBN C 1 V34 P289 Y293 R300 V33 P250 Y254 R261 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o C 3.60 BS03 LBN C 2 K91 G99 L101 W104 Y111 I112 L115 K90 G96 L98 W101 Y108 I109 L112 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o C 3.60 BS04 LBN C 3 F235 L237 Q274 L275 V282 F196 L198 Q235 L236 V243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o D 3.60 BS01 LBN C 4 L275 I279 L236 I240 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o D 3.60 BS02 LBN D 1 V34 P289 Y293 R300 V33 P250 Y254 R261 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o D 3.60 BS03 LBN D 2 K91 G99 L101 W104 Y111 I112 L115 K90 G96 L98 W101 Y108 I109 L112 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o D 3.60 BS04 LBN D 3 F235 L237 Q274 L275 V282 F196 L198 Q235 L236 V243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o E 3.60 BS01 LBN D 4 L275 I279 L236 I240 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o E 3.60 BS02 LBN E 1 V34 P289 Y293 R300 V33 P250 Y254 R261 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o E 3.60 BS03 LBN E 2 K91 G99 L101 W104 Y111 I112 L115 K90 G96 L98 W101 Y108 I109 L112 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o E 3.60 BS04 LBN E 3 F235 L237 Q274 L275 V282 F196 L198 Q235 L236 V243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o E 3.60 BS05 LBN F 1 K91 W104 K90 W101 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o F 3.60 BS01 LBN E 4 L275 I279 L236 I240 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o F 3.60 BS02 LBN F 2 V34 P289 Y293 R300 V33 P250 Y254 R261 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o F 3.60 BS03 LBN F 3 K91 G99 L101 W104 Y111 I112 L115 K90 G96 L98 W101 Y108 I109 L112 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o F 3.60 BS04 LBN F 1 F235 L237 Q274 L275 V282 F196 L198 Q235 L236 V243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o F 3.60 BS05 LBN G 1 K91 W104 K90 W101 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o G 3.60 BS01 LBN F 4 L275 I279 L236 I240 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o G 3.60 BS02 LBN G 2 V34 P289 Y293 R300 V33 P250 Y254 R261 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o G 3.60 BS03 LBN G 3 K91 G99 L101 W104 Y111 I112 L115 K90 G96 L98 W101 Y108 I109 L112 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7f8o G 3.60 BS04 LBN G 1 F235 L237 Q274 L275 V282 F196 L198 Q235 L236 V243 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLSEGYNDLSLYNLFLEENISEVKSYKCLKVLENI 7fj2 A 3.10 BS01 NUC C 1 R236 S240 Y241 M242 N283 S284 H287 R4 S8 Y9 M10 N51 S52 H55 34973238 VSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIH 7fj2 A 3.10 BS02 NUC D 1 L259 R286 H287 S290 R297 S306 W308 L27 R54 H55 S58 R65 S74 W76 34973238 VSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIH 7fj2 B 3.10 BS01 NUC C 1 L259 R286 H287 S290 R297 W308 L24 R51 H52 S55 R62 W73 34973238 RPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIH 7fj2 B 3.10 BS02 NUC D 1 S240 Y241 N283 S284 H287 H292 S5 Y6 N48 S49 H52 H57 34973238 RPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIH 7fj2 E 3.10 BS01 NUC G 1 S240 Y241 M242 N283 S284 H287 S8 Y9 M10 N51 S52 H55 34973238 VSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIH 7fj2 E 3.10 BS02 NUC H 1 K260 R286 H287 S290 R297 S306 W308 K28 R54 H55 S58 R65 S74 W76 34973238 VSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIH 7fj2 F 3.10 BS01 NUC G 1 L259 K260 R286 H287 S290 R297 S306 W308 L28 K29 R55 H56 S59 R66 S75 W77 34973238 SVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIH 7fj2 F 3.10 BS02 NUC H 1 R236 S240 Y241 G280 N283 S284 H287 R5 S9 Y10 G49 N52 S53 H56 34973238 SVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIH 7le3 B 1.87 BS01 K19 A 1 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 I84 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le3 A 1.87 BS01 K19 A 1 D25 G27 A28 D29 D30 G48 G49 I50 P81 I84 D25 G27 A28 D29 D30 G48 G49 I50 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le4 B 1.99 BS01 K2D A 1 D25 G27 A28 D29 D30 V32 G48 G49 I50 P81 I84 D25 G27 A28 D29 D30 V32 G48 G49 I50 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le4 A 1.99 BS01 K2D A 1 D25 G27 A28 D29 D30 G48 G49 I50 P81 V82 I84 D25 G27 A28 D29 D30 G48 G49 I50 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le5 B 1.86 BS01 K2E A 1 R8 D25 G27 A28 D29 D30 V32 G48 G49 I50 P81 V82 I84 R8 D25 G27 A28 D29 D30 V32 G48 G49 I50 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le5 A 1.86 BS01 K2E A 1 D25 G27 A28 D29 D30 G48 G49 I50 P81 V82 I84 D25 G27 A28 D29 D30 G48 G49 I50 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le6 B 1.96 BS01 A61 A 1 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 V82 I84 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le6 A 1.96 BS01 A61 A 1 D25 G27 A28 D29 D30 G48 G49 I50 P81 I84 D25 G27 A28 D29 D30 G48 G49 I50 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le7 B 1.98 BS01 KGQ A 1 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 I84 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le7 A 1.98 BS01 KGQ A 1 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 G52 F53 V82 I84 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 G52 F53 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le8 A 1.64 BS01 XUM A 1 L23 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 G52 F53 V82 I84 L23 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 G52 F53 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le8 B 1.64 BS01 XUM A 1 R8 L23 D25 G27 A28 D30 V32 G48 G49 I50 P81 V82 I84 R8 L23 D25 G27 A28 D30 V32 G48 G49 I50 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le9 A 1.80 BS01 XUP A 1 D25 G27 A28 D29 D30 G48 G49 I50 F53 V82 I84 D25 G27 A28 D29 D30 G48 G49 I50 F53 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7le9 B 1.80 BS01 XUP A 1 R8 L23 D25 G27 A28 D30 V32 G48 G49 I50 P81 V82 I84 R8 L23 D25 G27 A28 D30 V32 G48 G49 I50 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lea B 2.00 BS01 XUS A 1 D25 G27 A28 D30 V32 G48 G49 P81 I84 D25 G27 A28 D30 V32 G48 G49 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lea A 2.00 BS01 XUS A 1 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 P81 I84 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7leb B 1.89 BS01 XUV A 1 D25 G27 A28 D30 V32 I47 G48 G49 P81 D25 G27 A28 D30 V32 I47 G48 G49 P81 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7leb A 1.89 BS01 XUV A 1 L23 D25 G27 A28 D29 D30 G48 G49 I50 F53 V82 I84 L23 D25 G27 A28 D29 D30 G48 G49 I50 F53 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lec B 1.94 BS01 XVP B 1 D25 G27 A28 D29 D30 V32 I47 G48 G49 L76 P81 I84 D25 G27 A28 D29 D30 V32 I47 G48 G49 L76 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lec A 1.94 BS01 XVP B 1 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 P81 V82 I84 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7led B 2.00 BS01 XVM A 1 D25 G27 A28 D29 D30 V32 G48 G49 P81 D25 G27 A28 D29 D30 V32 G48 G49 P81 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7led A 2.00 BS01 XVM A 1 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 V82 I84 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lee A 1.80 BS01 XVJ A 1 L23 D25 G27 A28 D29 D30 G48 G49 I50 G52 F53 V82 I84 L23 D25 G27 A28 D29 D30 G48 G49 I50 G52 F53 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lee B 1.80 BS01 XVJ A 1 R8 L23 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 I84 R8 L23 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lef B 1.93 BS01 XVS A 1 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 V82 I84 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lef A 1.93 BS01 XVS A 1 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 P81 I84 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7leg B 1.96 BS01 XVY A 1 D25 G27 A28 D29 D30 V32 I47 G48 G49 P81 V82 I84 D25 G27 A28 D29 D30 V32 I47 G48 G49 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7leg A 1.96 BS01 XVY A 1 D25 G27 A28 D29 D30 G48 G49 I50 F53 P81 I84 D25 G27 A28 D29 D30 G48 G49 I50 F53 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7leh B 2.00 BS01 XW4 A 1 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 V82 I84 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7leh A 2.00 BS01 XW4 A 1 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 P81 V82 I84 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 F53 P81 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lei B 1.94 BS01 XVV A 1 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 I84 R8 D25 G27 A28 D30 V32 I47 G48 G49 I50 P81 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lei A 1.94 BS01 XVV A 1 L23 D25 G27 A28 D29 D30 G48 G49 I50 F53 V82 I84 L23 D25 G27 A28 D29 D30 G48 G49 I50 F53 V82 I84 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 7lgx A 1.80 BS01 F9F A 1 F22 E49 A59 D60 I64 L100 L127 A129 I153 Y175 T183 G184 F212 G213 G234 S235 F22 E49 A59 D60 I64 L100 L127 A129 I153 Y175 T183 G184 F204 G205 G226 S227 4.2.1.20 MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGLHHLIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLPKQMLAELRSFVSAMKAASRA 7lgx B 1.80 BS01 BZI B 1 K87 E109 L166 G189 T190 G233 F306 K86 E108 L165 G188 T189 G232 F305 4.2.1.20 TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLTDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGE 7lgx B 1.80 BS02 BZI B 2 T3 L4 L5 N6 T2 L3 L4 N5 4.2.1.20 TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLTDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGE 7lgx B 1.80 BS03 0JO B 1 A85 H86 K87 T110 G111 A112 G113 Q114 H115 T190 C230 G232 G233 G234 S235 N236 G303 E350 S377 A84 H85 K86 T109 G110 A111 G112 Q113 H114 T189 C229 G231 G232 G233 S234 N235 G302 E349 S376 4.2.1.20 TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLTDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGE 7lgx B 1.80 BS04 CS B 1 T66 T69 T71 T65 T68 T70 4.2.1.20 TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLTDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGE 7lgx B 1.80 BS05 CS B 2 V231 G232 G268 P270 L304 F306 S308 V230 G231 G267 P269 L303 F305 S307 4.2.1.20 TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLTDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGE 7lw1 A 2.90 BS01 YG1 A 1 M174 D179 L182 F308 I311 K315 N341 F537 D542 V545 Y578 F670 N673 W740 L744 M164 D169 L172 F298 I301 K305 N331 F527 D532 V535 Y568 F660 N663 W730 L734 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 A 2.90 BS02 FBP A 1 A409 R470 T527 S529 M572 E628 H660 Q663 R734 A399 R460 T517 S519 M562 E618 H650 Q653 R724 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 A 2.90 BS03 F6P A 1 I165 D166 M208 R210 E264 H298 R301 I155 D156 M198 R200 E254 H288 R291 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 A 2.90 BS04 ADP A 1 G24 R88 C89 F92 T93 G118 G120 S121 G124 I127 G14 R78 C79 F82 T83 G108 G110 S111 G114 I117 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 A 2.90 BS05 FBP D 1 R565 R654 R555 R644 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 A 2.90 BS06 F6P D 1 R201 R292 R191 R282 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 D 2.90 BS01 FBP A 1 R565 R654 R555 R644 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 D 2.90 BS02 F6P A 1 R201 R292 R191 R282 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 D 2.90 BS03 YG1 D 1 M174 D179 L182 F308 I311 K315 N341 F537 D542 V545 Y578 F670 N673 W740 L744 M164 D169 L172 F298 I301 K305 N331 F527 D532 V535 Y568 F660 N663 W730 L734 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 D 2.90 BS04 FBP D 1 A409 R470 T527 S529 M572 E628 H660 Q663 R734 A399 R460 T517 S519 M562 E618 H650 Q653 R724 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 D 2.90 BS05 F6P D 1 I165 D166 M208 R210 E264 H298 R301 I155 D156 M198 R200 E254 H288 R291 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 D 2.90 BS06 ADP D 1 G24 R88 C89 F92 T93 G118 G120 S121 G124 I127 G14 R78 C79 F82 T83 G108 G110 S111 G114 I117 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 E 2.90 BS01 YG1 E 1 M174 D179 L182 F308 I311 K315 N341 F537 D542 V545 Y578 F670 N673 W740 L744 M164 D169 L172 F298 I301 K305 N331 F527 D532 V535 Y568 F660 N663 W730 L734 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 E 2.90 BS02 FBP E 1 A409 R470 T527 S529 M572 E628 H660 Q663 R734 A399 R460 T517 S519 M562 E618 H650 Q653 R724 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 E 2.90 BS03 F6P E 1 I165 D166 M208 R210 E264 H298 R301 I155 D156 M198 R200 E254 H288 R291 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 E 2.90 BS04 ADP E 1 G24 R88 C89 F92 T93 G118 G120 S121 G124 I127 G14 R78 C79 F82 T83 G108 G110 S111 G114 I117 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 E 2.90 BS05 FBP F 1 R565 R654 R555 R644 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 E 2.90 BS06 F6P F 1 R201 R292 R191 R282 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 F 2.90 BS01 FBP E 1 R565 R654 R555 R644 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 F 2.90 BS02 F6P E 1 R201 R292 R191 R282 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 F 2.90 BS03 YG1 F 1 M174 D179 L182 F308 I311 K315 N341 F537 D542 V545 Y578 F670 N673 W740 L744 M164 D169 L172 F298 I301 K305 N331 F527 D532 V535 Y568 F660 N663 W730 L734 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 F 2.90 BS04 FBP F 1 A409 R470 T527 S529 M572 E628 H660 Q663 R734 A399 R460 T517 S519 M562 E618 H650 Q653 R724 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 F 2.90 BS05 F6P F 1 I165 D166 M208 R210 E264 H298 R301 I155 D156 M198 R200 E254 H288 R291 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7lw1 F 2.90 BS06 ADP F 1 G24 R88 C89 F92 T93 G118 G120 S121 G124 I127 G14 R78 C79 F82 T83 G108 G110 S111 G114 I117 2.7.1.11 34320407 ASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQY 7mfd A 3.66 BS01 ZN A 1 C248 C251 C272 C84 C87 C108 2.7.11.1 IVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQEKKPIGWDTDISWLTGEELHVEVLHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSRDRSSSAPNVHDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGF 7mfd A 3.66 BS02 ZN A 2 H235 C261 C264 H71 C97 C100 2.7.11.1 IVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQEKKPIGWDTDISWLTGEELHVEVLHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSRDRSSSAPNVHDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGF 7mfd B 3.66 BS01 CHU B 1 L118 I126 V127 I141 M143 R189 D190 C207 D208 F209 G210 V211 L215 M219 M230 R234 L67 I75 V76 I90 M92 R138 D139 C156 D157 F158 G159 V160 L164 M168 M179 R183 2.7.12.2 AFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQ 7mfe A 4.07 BS01 ZN A 1 C248 H269 C84 H105 2.7.11.1 IVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQEKKPIGWDTDISWLTGEELHVEVLHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCRDRSSSAPNVHDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGF 7mfe A 4.07 BS02 ZN A 2 H235 C264 H71 C100 2.7.11.1 IVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQEKKPIGWDTDISWLTGEELHVEVLHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCRDRSSSAPNVHDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGF 7mff A 3.89 BS01 215 A 1 I463 G464 S465 V471 A481 K483 T529 W531 C532 F583 D594 I15 G16 S17 V23 A33 K35 T81 W83 C84 F135 D146 2.7.11.1 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPS 7mff B 3.89 BS01 215 B 1 S465 V471 A481 K483 I527 T529 Q530 W531 C532 Y538 N580 F583 D594 S17 V23 A33 K35 I79 T81 Q82 W83 C84 Y90 N132 F135 D146 2.7.11.1 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSL 7nwx A 1.80 BS01 ZN A 1 H41 C145 H41 C145 34278402 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 7od3 A 2.80 BS01 EIC A 1 F338 V341 I358 A363 Y365 Y369 F377 L387 V395 I434 L513 F245 V248 I265 A270 Y272 Y276 F284 L294 V302 I341 L420 35017512 AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHANPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNNVVIKVCEFQFCNDPFLFRVYSSANNCTFEYVSNLREFVFKNIDGYFKIYSKHTPIDLPQGFSALEPLVDLPIGINITRFQTLLAAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSLGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 7od3 B 2.80 BS01 EIC B 1 F338 V341 I358 Y365 Y369 F374 F377 F392 V395 I434 V524 F245 V248 I265 Y272 Y276 F281 F284 F299 V302 I341 V431 35017512 AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHANPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNNVVIKVCEFQFCNDPFLFRVYSSANNCTFEYVSNLREFVFKNIDGYFKIYSKHTPIDLPQGFSALEPLVDLPIGINITRFQTLLAAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSLGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 7od3 C 2.80 BS01 EIC C 1 P337 F338 A363 Y365 L368 Y369 F377 L387 V395 I434 P244 F245 A270 Y272 L275 Y276 F284 L294 V302 I341 35017512 AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHANPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNNVVIKVCEFQFCNDPFLFRVYSSANNCTFEYVSNLREFVFKNIDGYFKIYSKHTPIDLPQGFSALEPLVDLPIGINITRFQTLLAAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSLGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 7odl A 3.03 BS01 EIC A 1 F338 V341 A363 Y365 Y369 F374 F377 L387 F392 V395 I434 L513 F249 V252 A274 Y276 Y280 F285 F288 L298 F303 V306 I345 L424 35017512 AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHANPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLFRVYSSANNCTFEYVSQPNLREFVFKNIDGYFKIYSKHTPIDLPQGFSALEPLVDLPIGINITRFQTLLAAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTIASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSLGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 7odl B 3.03 BS01 EIC B 1 I358 A363 Y365 Y369 F377 L387 F392 V395 I269 A274 Y276 Y280 F288 L298 F303 V306 35017512 AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHANPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLFRVYSSANNCTFEYVSQPNLREFVFKNIDGYFKIYSKHTPIDLPQGFSALEPLVDLPIGINITRFQTLLAAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTIASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSLGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 7odl C 3.03 BS01 EIC C 1 F338 V341 A363 Y365 L387 F392 V395 L513 F249 V252 A274 Y276 L298 F303 V306 L424 35017512 AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHANPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLFRVYSSANNCTFEYVSQPNLREFVFKNIDGYFKIYSKHTPIDLPQGFSALEPLVDLPIGINITRFQTLLAAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTIASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSLGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 7on9 A 1.63 BS01 FAD A 1 I8 G9 G11 P12 A13 I31 E32 N33 R34 R44 A45 G46 V47 Q102 V127 C160 D161 G162 P166 V268 G287 D288 P295 A298 K299 G300 L301 N302 I8 G9 G11 P12 A13 I31 E32 N33 R34 R44 A45 G46 V47 Q102 V127 C160 D161 G162 P166 V268 G287 D288 P295 A298 K299 G300 L301 N302 1.14.13.33 34982998 MRTQVGIIGAGPAGLLLSHLLYLQGIESIIIENRTREEIEGTIRAGVLEQGTVDLMNQMGVGARMMKEGHFHEGFELRFNGRGHRINVHELTGGKYVTVYAQHEVIKDLVAARLQTGGQIHFNVGDVSLHDVDTSSPKIRFRPNKDGELQEIECDFIAGCDGFRGPSRPAIPQSVRKEYQKVYPFSWLGILVEAPPSAHELIYANHERGFALVSTRSPQIQRLYLQVDAQDHIDNWSDDRIWSELHARLETRDGFKLLEGPIFQKGIVSMRSFVCDPMQHGRLFLAGDAAHIVPPTGAKGLNLAAADVQVLARGLEAYYKAGKMEILNRCTEICLRRIWKAERFSWFMTTMLHRDQGHTPFERGIQLAELDYVTSSRAASTSLAENYIGLPME 7on9 B 1.63 BS01 FAD B 1 I8 G9 G11 P12 A13 I31 E32 N33 R34 R44 A45 G46 V47 Q102 V127 C160 D161 G162 P166 V268 G287 D288 P295 A298 K299 G300 L301 N302 I8 G9 G11 P12 A13 I31 E32 N33 R34 R44 A45 G46 V47 Q102 V127 C160 D161 G162 P166 V268 G287 D288 P295 A298 K299 G300 L301 N302 1.14.13.33 34982998 MRTQVGIIGAGPAGLLLSHLLYLQGIESIIIENRTREEIEGTIRAGVLEQGTVDLMNQMGVGARMMKEGHFHEGFELRFNGRGHRINVHELTGGKYVTVYAQHEVIKDLVAARLQTGGQIHFNVGDVSLHDVDTSSPKIRFRPNKDGELQEIECDFIAGCDGFRGPSRPAIPQSVRKEYQKVYPFSWLGILVEAPPSAHELIYANHERGFALVSTRSPQIQRLYLQVDAQDHIDNWSDDRIWSELHARLETRDGFKLLEGPIFQKGIVSMRSFVCDPMQHGRLFLAGDAAHIVPPTGAKGLNLAAADVQVLARGLEAYYKAGKMEILNRCTEICLRRIWKAERFSWFMTTMLHRDQGHTPFERGIQLAELDYVTSSRAASTSLAENYIGLPM 7on9 C 1.63 BS01 FAD C 1 I8 G9 G11 P12 A13 I31 E32 N33 R34 R44 A45 V47 Q102 V127 C160 D161 G162 P166 G287 D288 P295 A298 K299 G300 L301 N302 I8 G9 G11 P12 A13 I31 E32 N33 R34 R44 A45 V47 Q102 V127 C160 D161 G162 P166 G287 D288 P295 A298 K299 G300 L301 N302 1.14.13.33 34982998 MRTQVGIIGAGPAGLLLSHLLYLQGIESIIIENRTREEIEGTIRAGVLEQGTVDLMNQMGVGARMMKEGHFHEGFELRFNGRGHRINVHELTGGKYVTVYAQHEVIKDLVAARLQTGGQIHFNVGDVSLHDVDTSSPKIRFRPNKDGELQEIECDFIAGCDGFRGPSRPAIPQSVRKEYQKVYPFSWLGILVEAPPSAHELIYANHERGFALVSTRSPQIQRLYLQVDAQDHIDNWSDDRIWSELHARLETRDGFKLLEGPIFQKGIVSMRSFVCDPMQHGRLFLAGDAAHIVPPTGAKGLNLAAADVQVLARGLEAYYKAGKMEILNRCTEICLRRIWKAERFSWFMTTMLHRDQGHTPFERGIQLAELDYVTSSRAASTSLAENYIGLP 7on9 D 1.63 BS01 FAD D 1 I8 G9 G11 P12 A13 I31 E32 N33 R34 R44 A45 V47 Q102 V127 C160 D161 G162 P166 G287 D288 P295 A298 K299 G300 L301 N302 I8 G9 G11 P12 A13 I31 E32 N33 R34 R44 A45 V47 Q102 V127 C160 D161 G162 P166 G287 D288 P295 A298 K299 G300 L301 N302 1.14.13.33 34982998 MRTQVGIIGAGPAGLLLSHLLYLQGIESIIIENRTREEIEGTIRAGVLEQGTVDLMNQMGVGARMMKEGHFHEGFELRFNGRGHRINVHELTGGKYVTVYAQHEVIKDLVAARLQTGGQIHFNVGDVSLHDVDTSSPKIRFRPNKDGELQEIECDFIAGCDGFRGPSRPAIPQSVRKEYQKVYPFSWLGILVEAPPSAHELIYANHERGFALVSTRSPQIQRLYLQVDAQDHIDNWSDDRIWSELHARLETRDGFKLLEGPIFQKGIVSMRSFVCDPMQHGRLFLAGDAAHIVPPTGAKGLNLAAADVQVLARGLEAYYKAGKMEILNRCTEICLRRIWKAERFSWFMTTMLHRDQGHTPFERGIQLAELDYVTSSRAASTSLAENYIGL 7oon A 2.80 BS01 HEM A 1 M59 P60 M63 K64 M78 V80 D173 P174 P175 M53 P54 M57 K58 M72 V74 D167 P168 P169 NSLFGSVETWPWQVLSTGGKEDVSYEERACEGGKFATVEVTDKPVDEALREAMPKIMKYVGGTNDKGVGMGMTVPVSFAVFPNEDGSLQKKLKVWFRIPNQFQGSPPAPSDESVKIEEREGITVYSTQFGGYAKEADYVAHATQLRTTLEGTPATYQGDVYYCAGYDPPMKPYGRRNEVWLVKA 7oon B 2.80 BS01 HEM B 1 F10 M59 P60 M63 M78 V80 V82 Y172 D173 P174 P175 F6 M55 P56 M59 M74 V76 V78 Y168 D169 P170 P171 GSNSLFGSVETWPWQVLSTGGKEDVSYEERACEGGKFATVEVTDKPVDEALREAMPKIMKYVGGTNDKGVGMGMTVPVSFAVFPNEDGSLQKKLKVWFRIPNQFQGSPPAPSDESVKIEEREGITVYSTQFGGYAKEADYVAHATQLRTTLEGTPATYQGDVYYCAGYDPPMKPYGRRNEVWLVK 7p1k B 3.64 BS01 Y01 B 1 W230 Q231 F234 F238 I279 L280 T283 G284 M291 V302 G305 V306 W152 Q153 F156 F160 I201 L202 T205 G206 M213 V218 G221 V222 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k B 3.64 BS02 T7X B 1 W336 V387 W252 V303 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k B 3.64 BS03 T7X B 2 K170 W171 A174 L175 K92 W93 A96 L97 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k B 3.64 BS04 Y01 B 2 I94 L95 W97 A98 W101 L109 I16 L17 W19 A20 W23 L31 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k B 3.64 BS05 Y01 B 3 V90 V93 I94 W97 L109 P110 F115 M119 Y122 I126 V12 V15 I16 W19 L31 P32 F37 M41 Y44 I48 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k B 3.64 BS06 Y01 B 4 P110 F115 M119 C123 I126 I161 N164 P32 F37 M41 C45 I48 I83 N86 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k B 3.64 BS07 Y01 A 1 L345 L348 S352 F356 L261 L264 S268 F272 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k B 3.64 BS08 T7X A 1 V99 V103 T104 L114 V21 V25 T26 L36 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k A 3.64 BS01 T7X B 3 V99 V103 T104 L114 V21 V25 T26 L36 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k A 3.64 BS02 Y01 B 5 L345 L348 S352 F356 L261 L264 S268 F272 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k A 3.64 BS03 Y01 A 1 I94 L95 W97 A98 W101 L109 I16 L17 W19 A20 W23 L31 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k A 3.64 BS04 Y01 A 2 V93 I94 W97 P110 F115 M119 Y122 I126 V15 I16 W19 P32 F37 M41 Y44 I48 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k A 3.64 BS05 Y01 A 3 P110 F115 M119 C123 I126 I161 N164 P32 F37 M41 C45 I48 I83 N86 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k A 3.64 BS06 Y01 A 4 W230 Q231 F234 F238 L280 T283 G284 T287 M291 V302 G305 V306 W152 Q153 F156 F160 L202 T205 G206 T209 M213 V218 G221 V222 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k A 3.64 BS07 T7X A 2 W336 V387 A391 W252 V303 A307 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p1k A 3.64 BS08 T7X A 1 L114 K170 W171 A174 L175 L36 K92 W93 A96 L97 PRGLLARVITNVTMVILLWAVVWSVTGSECLPGGNLFGIIMLFYCAIIGGKLFGLIKLPTLPPLPPLLGMLLAGFLIRNVPVISDNIQIKHKWSSALRSIALSVILVRAGLGLDSNALKKLKGVCVRLSLGPCLIEACTSAVLAYFLMGLPWQWGFMLGFVLGAVSPAVVVPSMLLLQEGGYGVEKGIPTLLMAAGSFDDILAITGFNTCLGMAFFNVLKGVLEVIIGVVTGLVLGFFIQYFPSSDQDNLVWKRAFLVLGLSVLAVFSSTYFGFPGSGGLCTLVTAFLAGRGWASTKTDVEKVIAVAWDIFQPLLFGLIGAEVLITALRPETIGLCVATLGIAVLIRILVTYLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEGYGMDVLTVAFLSIIITAPVGSLLIGLLGPRLLQ 7p7p A 3.00 BS01 62S A 1 E200 P333 G334 A335 M336 E337 W363 R366 V367 H370 E371 H374 E393 K397 F450 Y455 Y892 E151 P284 G285 A286 M287 E288 W314 R317 V318 H321 E322 H325 E344 K348 F401 Y406 Y841 3.4.11.- PGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTRH 7p7p A 3.00 BS02 PDO A 1 D678 T954 D627 T903 3.4.11.- PGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTRH 7p7p A 3.00 BS03 ZN A 1 H370 H374 E393 H321 H325 E344 3.4.11.- PGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTRH 7p7p B 3.00 BS01 62S B 1 E200 P333 G334 A335 M336 E337 H370 E371 H374 E393 K397 E423 F450 E452 Y455 N456 Y892 E150 P283 G284 A285 M286 E287 H320 E321 H324 E343 K347 E373 F400 E402 Y405 N406 Y802 3.4.11.- GAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCNAEVKEMMTTWTLQKGIPLLVVKQCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKAMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTR 7p7p B 3.00 BS02 ZN B 1 H370 H374 E393 H320 H324 E343 3.4.11.- GAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCNAEVKEMMTTWTLQKGIPLLVVKQCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKAMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTR 7pdf B 3.80 BS01 GSP B 1 G49 E50 G52 K53 S54 T55 D173 C174 R199 R201 T204 G226 N292 K293 D295 L296 C365 A366 V367 G22 E23 G25 K26 S27 T28 D124 C125 R150 R152 T155 G177 N243 K244 D246 L247 C316 A317 V318 KQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ 7pdf B 3.80 BS02 MG B 1 S54 T204 S27 T155 KQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ 7pf1 A 2.10 BS01 MG A 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 A 2.10 BS02 MG A 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 B 2.10 BS01 MG B 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 B 2.10 BS02 MG B 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 C 2.10 BS01 MG C 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 C 2.10 BS02 MG C 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 D 2.10 BS01 MG D 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 D 2.10 BS02 MG D 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 E 2.10 BS01 MG E 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 E 2.10 BS02 MG E 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 F 2.10 BS01 MG F 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 F 2.10 BS02 MG F 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 G 2.10 BS01 MG G 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 G 2.10 BS02 MG G 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 H 2.10 BS01 MG H 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 H 2.10 BS02 MG H 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 I 2.10 BS01 MG I 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 I 2.10 BS02 MG I 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 J 2.10 BS01 MG J 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 J 2.10 BS02 MG J 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 K 2.10 BS01 MG K 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 K 2.10 BS02 MG K 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 L 2.10 BS01 MG L 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 L 2.10 BS02 MG L 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 M 2.10 BS01 MG M 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 M 2.10 BS02 MG M 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 N 2.10 BS01 MG N 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 N 2.10 BS02 MG N 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 O 2.10 BS01 MG O 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 O 2.10 BS02 MG O 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 P 2.10 BS01 MG P 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 P 2.10 BS02 MG P 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 Q 2.10 BS01 MG Q 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 Q 2.10 BS02 MG Q 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 R 2.10 BS01 MG R 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 R 2.10 BS02 MG R 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 S 2.10 BS01 MG S 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 S 2.10 BS02 MG S 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 T 2.10 BS01 MG T 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 T 2.10 BS02 MG T 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 U 2.10 BS01 MG U 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 U 2.10 BS02 MG U 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 V 2.10 BS01 MG V 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 V 2.10 BS02 MG V 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 W 2.10 BS01 MG W 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 W 2.10 BS02 MG W 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 X 2.10 BS01 MG X 1 Q61 E64 Q56 E59 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pf1 X 2.10 BS02 MG X 2 E30 E65 H68 E25 E60 H63 35017666 ASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 7pfs A 2.70 BS01 7OO A 1 E200 P333 A335 M336 E337 R345 W363 H370 E371 H374 E393 F450 D451 E452 Y455 Y892 E153 P286 A288 M289 E290 R298 W316 H323 E324 H327 E346 F403 D404 E405 Y408 Y845 3.4.11.- EDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTRHH 7pfs A 2.70 BS02 ZN A 1 H370 H374 E393 H323 H327 E346 3.4.11.- EDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTRHH 7pfs B 2.70 BS01 7OO B 1 E200 P201 P333 G334 A335 M336 E337 R345 W363 H370 E371 H374 E393 F450 D451 E452 Y455 Y892 E151 P152 P284 G285 A286 M287 E288 R296 W314 H321 E322 H325 E344 F401 D402 E403 Y406 Y806 3.4.11.- PGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSNAEVKEMMTTWTLQKGIPLLVVKDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMV 7pfs B 2.70 BS02 ZN B 1 H370 H374 E393 H321 H325 E344 3.4.11.- PGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSNAEVKEMMTTWTLQKGIPLLVVKDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMV 7ppj A 3.44 BS01 ZN A 1 H266 C268 P272 C303 H238 C240 P244 C275 35037067 LRIDVDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEIENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAGVPLATLCSNLYHRERTSTDVMDSQEALAFLKCRTQNVSAAALFDRKRLQYLEKLNLPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRDLINTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNQIYPESYNFMTPQHMEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQHIIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLD 7pzc A 3.90 BS01 ADP A 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R158 Y159 T160 A201 G203 I204 G205 K206 T207 I208 F347 Y355 L387 W390 H496 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc A 3.90 BS02 8GI A 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A201 A202 R325 M382 I385 T413 Y417 I548 F549 R552 L602 E603 Y606 M635 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc B 3.90 BS01 ADP B 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R28 Y29 T30 A71 G73 I74 G75 K76 T77 I78 F217 Y225 L257 W260 H366 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc B 3.90 BS02 8GI B 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A71 A72 R195 M252 I255 T283 Y287 I418 F419 R422 L472 E473 Y476 M505 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc C 3.90 BS01 ADP C 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R28 Y29 T30 A71 G73 I74 G75 K76 T77 I78 F217 Y225 L257 W260 H366 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc C 3.90 BS02 8GI C 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A71 A72 R195 M252 I255 T283 Y287 I418 F419 R422 L472 E473 Y476 M505 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc D 3.90 BS01 ADP D 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R28 Y29 T30 A71 G73 I74 G75 K76 T77 I78 F217 Y225 L257 W260 H366 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc D 3.90 BS02 8GI D 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A71 A72 R195 M252 I255 T283 Y287 I418 F419 R422 L472 E473 Y476 M505 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc E 3.90 BS01 ADP E 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R28 Y29 T30 A71 G73 I74 G75 K76 T77 I78 F217 Y225 L257 W260 H366 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc E 3.90 BS02 8GI E 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A71 A72 R195 M252 I255 T283 Y287 I418 F419 R422 L472 E473 Y476 M505 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc F 3.90 BS01 ADP F 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R28 Y29 T30 A71 G73 I74 G75 K76 T77 I78 F217 Y225 L257 W260 H366 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc F 3.90 BS02 8GI F 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A71 A72 R195 M252 I255 T283 Y287 I418 F419 R422 L472 E473 Y476 M505 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc G 3.90 BS01 ADP G 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R28 Y29 T30 A71 G73 I74 G75 K76 T77 I78 F217 Y225 L257 W260 H366 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc G 3.90 BS02 8GI G 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A71 A72 R195 M252 I255 T283 Y287 I418 F419 R422 L472 E473 Y476 M505 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc H 3.90 BS01 ADP H 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R158 Y159 T160 A201 G203 I204 G205 K206 T207 I208 F347 Y355 L387 W390 H496 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc H 3.90 BS02 8GI H 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A201 A202 R325 M382 I385 T413 Y417 I548 F549 R552 L602 E603 Y606 M635 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc I 3.90 BS01 ADP I 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R28 Y29 T30 A71 G73 I74 G75 K76 T77 I78 F217 Y225 L257 W260 H366 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc I 3.90 BS02 8GI I 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A71 A72 R195 M252 I255 T283 Y287 I418 F419 R422 L472 E473 Y476 M505 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc J 3.90 BS01 ADP J 1 R167 Y168 T169 A227 G229 I230 G231 K232 T233 I234 F373 Y381 L413 W416 H522 R28 Y29 T30 A71 G73 I74 G75 K76 T77 I78 F217 Y225 L257 W260 H366 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7pzc J 3.90 BS02 8GI J 1 A227 A228 R351 M408 I411 T439 Y443 I574 F575 R578 L628 E629 Y632 M661 A71 A72 R195 M252 I255 T283 Y287 I418 F419 R422 L472 E473 Y476 M505 KKDYRKKYRKYVRSRFQCIEESVSLNKRYTRLRLIKEHRSQSPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW 7q3z B 1.85 BS01 ZN B 1 H266 C268 C302 C303 H238 C240 C274 C275 35037067 VDTNECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEIENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAGVPLATLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPEGNINVSAAALFDRKRLQYLEKLNLPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMME 7q3z A 1.85 BS01 ZN A 1 H266 C268 C302 C303 H237 C239 C273 C274 35037067 IDVDTNCVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEIENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTGVPLATLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPEGNINVSAAALFDRKRLQYLEKLNLPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEA 7q5b A 3.98 BS01 NUC R 1 R77 Y116 P118 K119 Q121 R141 K197 A201 T202 Q203 V228 A232 D233 R364 G387 Y389 M390 K391 R61 Y100 P102 K103 Q105 R125 K181 A182 T183 Q184 V209 A213 D214 R345 G368 Y370 M371 K372 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRP 7q5b A 3.98 BS02 NUC S 1 R143 V166 T167 G168 P254 Q255 E261 Q265 R127 V150 T151 G152 P235 Q236 E242 Q246 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRP 7q5b A 3.98 BS03 NUC r 1 D164 T167 D225 R226 D227 V228 A251 K385 H418 K420 K421 H422 D148 T151 D206 R207 D208 V209 A232 K366 H399 K401 K402 H403 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRP 7q5b A 3.98 BS04 NUC t 1 L148 Q149 P150 L151 R185 K245 S246 T247 M248 S249 S250 H253 Q255 T256 G258 Q259 R262 T266 T298 R299 T300 M357 N361 K404 I406 N407 N409 A410 N426 L132 Q133 P134 L135 R169 K226 S227 T228 M229 S230 S231 H234 Q236 T237 G239 Q240 R243 T247 T279 R280 T281 M338 N342 K385 I387 N388 N390 A391 N407 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRP 7q5b A 3.98 BS05 NUC u 1 E59 T60 F61 F102 G103 V104 T105 V106 Q121 I125 K138 H140 R141 E43 T44 F45 F86 G87 V88 T89 V90 Q105 I109 K122 H124 R125 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRP 7q5b B 3.98 BS01 NUC R 1 V166 T167 G168 P254 Q255 E261 R262 I264 Q265 N268 V150 T151 G152 P238 Q239 E245 R246 I248 Q249 N252 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRPYPKNKPISSTERIKRAHEVTALIGIDTTHKTYLCHMQDVDPTLSVEYSEAEFCQIPERTRRSILA 7q5b B 3.98 BS02 NUC S 1 R77 Y116 Q121 R141 K197 T198 A201 V228 R229 A232 D233 R364 Y389 K391 K420 K421 T466 T467 R61 Y100 Q105 R125 K181 T182 A185 V212 R213 A216 D217 R348 Y369 K371 K400 K401 T444 T445 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRPYPKNKPISSTERIKRAHEVTALIGIDTTHKTYLCHMQDVDPTLSVEYSEAEFCQIPERTRRSILA 7q5b B 3.98 BS03 NUC s 1 D164 F165 D225 R226 D227 A251 N252 F384 K420 K421 D148 F149 D209 R210 D211 A235 N236 F368 K400 K401 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRPYPKNKPISSTERIKRAHEVTALIGIDTTHKTYLCHMQDVDPTLSVEYSEAEFCQIPERTRRSILA 7q5b B 3.98 BS04 NUC t 1 E59 T60 F61 F102 G103 V104 T105 V106 Q121 H140 R141 E43 T44 F45 F86 G87 V88 T89 V90 Q105 H124 R125 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRPYPKNKPISSTERIKRAHEVTALIGIDTTHKTYLCHMQDVDPTLSVEYSEAEFCQIPERTRRSILA 7q5b B 3.98 BS05 NUC u 1 L148 Q149 P150 L151 P152 R185 K188 K245 S246 T247 M248 S249 S250 H253 Q255 T256 G258 Q259 R262 T266 T298 R299 T300 E356 M357 N361 K404 I406 N407 N409 A410 L132 Q133 P134 L135 P136 R169 K172 K229 S230 T231 M232 S233 S234 H237 Q239 T240 G242 Q243 R246 T250 T282 R283 T284 E340 M341 N345 K384 I386 N387 N389 A390 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRPYPKNKPISSTERIKRAHEVTALIGIDTTHKTYLCHMQDVDPTLSVEYSEAEFCQIPERTRRSILA 7q5b C 3.98 BS01 NUC S 1 K119 H122 K102 H105 34848735 YYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYRPDAYPKNKPISSTERIKRAHEVTALIGIDTTHKTYLCHMQDVDPTLSVEYSEAEFCQIPERTRRSILANFRQLYE 7q5b D 3.98 BS01 NUC R 1 K119 H122 K103 H106 34848735 SYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNATAVELAKHLKALTIQTKEQLEHAQIEMETNNNQ 7q5b X 3.98 BS01 NUC R 1 R451 K455 R31 K35 34848735 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPNFDEYCCEIKK 7q5b X 3.98 BS02 NUC r 1 K452 A456 K32 A36 34848735 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPNFDEYCCEIKK 7q5b Y 3.98 BS01 NUC R 1 Q68 N69 R98 F99 I103 R105 T112 L114 T124 V161 S163 P191 F207 S209 K211 V213 Q8 N9 R38 F39 I43 R45 T52 L54 T64 V101 S103 P131 F147 S149 K151 V153 34848735 SGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM 7q5b Y 3.98 BS02 NUC r 1 V71 F99 F116 S118 K120 V122 Q158 N159 V161 F190 I194 R196 K201 V203 L205 T215 G216 V11 F39 F56 S58 K60 V62 Q98 N99 V101 F130 I134 R136 K141 V143 L145 T155 G156 34848735 SGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM 7q5b Z 3.98 BS01 NUC R 1 V117 Q118 R120 R218 R219 H249 V250 A251 E253 T254 S289 N293 V47 Q48 R50 R148 R149 H179 V180 A181 E183 T184 S219 N223 34848735 SALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDVEDGEARPPSFVKNRKKERKIPRNLHLLPTTDTYLSKVSDDPDNLEDVDDEELNAHLLNEEASKLKERIWIGLNADFLLE 7q5b Z 3.98 BS02 NUC r 1 S75 R76 T79 Y108 L112 F116 Q118 G119 R120 R121 S122 Y155 E253 N260 S5 R6 T9 Y38 L42 F46 Q48 G49 R50 R51 S52 Y85 E183 N190 34848735 SALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDVEDGEARPPSFVKNRKKERKIPRNLHLLPTTDTYLSKVSDDPDNLEDVDDEELNAHLLNEEASKLKERIWIGLNADFLLE 7q6r A 2.44 BS01 HEM A 1 L94 H101 R105 F112 A244 G245 T248 Q252 L285 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L366 L83 H90 R94 F101 A233 G234 T237 Q241 L274 L279 R287 F310 A337 F338 G339 H343 C345 I346 G347 L355 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r A 2.44 BS02 DEB A 1 M83 F84 L94 M178 L179 I243 A244 T248 S295 F296 M72 F73 L83 M167 L168 I232 A233 T237 S284 F285 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r B 2.44 BS01 HEM B 1 L94 H101 R105 F112 I157 A244 G245 T248 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L366 L83 H90 R94 F101 I146 A233 G234 T237 Q241 L279 R287 F310 A337 F338 G339 H343 C345 I346 G347 L355 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r B 2.44 BS02 DEB B 1 F84 L94 M178 L179 A244 T248 S295 F296 L396 I397 F73 L83 M167 L168 A233 T237 S284 F285 L385 I386 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r C 2.44 BS01 HEM C 1 V93 L94 H101 R105 F112 A244 G245 T248 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L366 V84 L85 H92 R96 F103 A235 G236 T239 Q243 L281 R289 F312 A339 F340 G341 H345 C347 I348 G349 L357 PADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r C 2.44 BS02 DEB C 1 M83 F84 L94 L179 I243 A244 T248 S295 F296 L396 I397 M74 F75 L85 L170 I234 A235 T239 S286 F287 L387 I388 PADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r D 2.44 BS01 HEM D 1 V93 L94 H101 R105 F112 A244 G245 T248 Q252 L285 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 V82 L83 H90 R94 F101 A233 G234 T237 Q241 L274 L279 R287 F310 A337 F338 G339 H343 C345 I346 G347 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r D 2.44 BS02 DEB D 1 M83 F84 L94 M178 L179 I243 A244 T248 S295 M72 F73 L83 M167 L168 I232 A233 T237 S284 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r E 2.44 BS01 HEM E 1 V93 L94 H101 R105 F112 A244 G245 T248 Q252 L290 R298 A348 F349 G350 H354 C356 I357 G358 G362 V80 L81 H88 R92 F99 A227 G228 T231 Q235 L273 R281 A331 F332 G333 H337 C339 I340 G341 G345 VPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRREDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r E 2.44 BS02 DEB E 1 M83 F84 L94 M178 L179 I243 A244 T248 V291 S295 F296 L396 I397 M70 F71 L81 M165 L166 I226 A227 T231 V274 S278 F279 L379 I380 VPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRREDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r F 2.44 BS01 HEM F 1 V93 L94 H101 R105 F112 A244 G245 T248 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 V82 L83 H90 R94 F101 A233 G234 T237 Q241 L277 R285 F308 A335 F336 G337 H341 C343 I344 G345 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVAALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6r F 2.44 BS02 DEB F 1 F84 L94 M178 L179 I243 T248 V291 S295 F296 L396 F73 L83 M167 L168 I232 T237 V278 S282 F283 L383 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPYPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVAALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x A 2.70 BS01 HEM A 1 V93 L94 H101 R105 F112 A244 G245 T248 Q252 L285 L290 R298 A348 F349 G350 H354 C356 I357 G358 L366 V83 L84 H91 R95 F102 A234 G235 T238 Q242 L275 L280 R288 A338 F339 G340 H344 C346 I347 G348 L356 ADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x A 2.70 BS02 DEB A 1 F84 L94 L179 I243 A244 T248 V291 S295 I397 F74 L84 L169 I233 A234 T238 V281 S285 I387 ADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x B 2.70 BS01 HEM B 1 V93 L94 H101 R105 F112 A244 G245 T248 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L366 V92 L93 H100 R104 F111 A243 G244 T247 Q251 L289 R297 F320 A347 F348 G349 H353 C355 I356 G357 L365 AATHTGPTPADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x B 2.70 BS02 DEB B 1 F84 L94 L179 I243 T248 V291 S295 F296 F83 L93 L178 I242 T247 V290 S294 F295 AATHTGPTPADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x C 2.70 BS01 HEM C 1 V93 L94 H101 R105 F112 I157 A244 G245 T248 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 V85 L86 H93 R97 F104 I149 A236 G237 T240 Q244 L282 R290 F313 A340 F341 G342 H346 C348 I349 G350 TPADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x C 2.70 BS02 DEB C 1 F84 L94 L179 Y240 I243 A244 T248 V291 S295 F296 I397 F76 L86 L171 Y232 I235 A236 T240 V283 S287 F288 I389 TPADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x D 2.70 BS01 HEM D 1 V93 L94 H101 R105 F112 A244 G245 T248 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L366 V82 L83 H90 R94 F101 A233 G234 T237 L279 R287 F310 A337 F338 G339 H343 C345 I346 G347 L355 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x D 2.70 BS02 DEB D 1 F84 L94 L179 Y240 I243 T248 V291 S295 F296 L396 I397 F73 L83 L168 Y229 I232 T237 V280 S284 F285 L385 I386 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x E 2.70 BS01 HEM E 1 V93 L94 H101 R105 F112 I157 A244 G245 T248 S249 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 G362 V81 L82 H89 R93 F100 I145 A232 G233 T236 S237 Q240 L278 R286 F309 A336 F337 G338 H342 C344 I345 G346 G350 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x E 2.70 BS02 DEB E 1 M83 F84 L94 L179 I243 A244 T248 V291 S295 F296 L396 M71 F72 L82 L167 I231 A232 T236 V279 S283 F284 L384 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x F 2.70 BS01 HEM F 1 V93 L94 H101 R105 F112 I157 A244 G245 T248 L290 R298 A348 F349 G350 H354 C356 I357 G358 V83 L84 H91 R95 F102 I147 A234 G235 T238 L280 R288 A338 F339 G340 H344 C346 I347 G348 ADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6x F 2.70 BS02 DEB F 1 F84 L94 L179 Y240 I243 T248 S295 F74 L84 L169 Y230 I233 T238 S285 ADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVYLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q6z A 3.59 BS01 CLR A 1 M64 G67 K68 L71 L75 W255 L303 V306 M64 G67 K68 L71 L75 W247 L295 V298 2.3.1.- 34890564 MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWSFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHTTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYYTNFSLELCTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYSHVGIAWAQTYATD 7q6z A 3.59 BS02 HEM A 1 S14 L15 H18 R250 W254 L257 L294 Y297 R323 C324 S326 T327 V482 W486 S14 L15 H18 R242 W246 L249 L286 Y289 R315 C316 S318 T319 V474 W478 2.3.1.- 34890564 MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWSFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHTTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYYTNFSLELCTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYSHVGIAWAQTYATD 7q6z A 3.59 BS03 9V3 A 1 V293 F296 Y300 F304 V325 M334 W335 F338 D339 L342 H379 W388 N392 L439 S442 N443 F446 V285 F288 Y292 F296 V317 M326 W327 F330 D331 L334 H371 W380 N384 L431 S434 N435 F438 2.3.1.- 34890564 MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWSFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHTTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYYTNFSLELCTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYSHVGIAWAQTYATD 7q87 A 1.73 BS01 ZN A 1 H69 E72 H204 H69 E72 H204 3.4.17.18 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC 7q87 A 1.73 BS02 HFA A 1 H69 R129 N146 R147 L211 A251 L254 Y255 T275 E277 H69 R129 N146 R147 L211 A251 L254 Y255 T275 E277 3.4.17.18 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC 7q87 A 1.73 BS03 HFA A 2 H69 E72 R129 H204 T205 Y206 Y255 E277 H69 E72 R129 H204 T205 Y206 Y255 E277 3.4.17.18 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC 7q87 A 1.73 BS04 CA A 1 S50 D51 E57 E59 S50 D51 E57 E59 3.4.17.18 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC 7q87 A 1.73 BS05 CA A 2 D56 E57 E59 E61 E104 R189 D56 E57 E59 E61 E104 R189 3.4.17.18 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC 7q87 A 1.73 BS06 CA A 3 S7 Y9 E14 S7 Y9 E14 3.4.17.18 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC 7q87 A 1.73 BS07 CA A 4 Y5 D291 E292 Y5 D291 E292 3.4.17.18 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC 7q87 A 1.73 BS08 CA A 5 D51 E57 E59 N101 D51 E57 E59 N101 3.4.17.18 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC 7q87 A 1.73 BS09 CA A 6 Y218 D220 Q250 D253 Y218 D220 Q250 D253 3.4.17.18 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC 7q89 A 2.08 BS01 HEM A 1 V93 L94 H101 R105 F112 A244 G245 T248 Q252 L285 L290 R298 A348 F349 G350 H354 C356 I357 G358 V82 L83 H90 R94 F101 A233 G234 T237 Q241 L274 L279 R287 A337 F338 G339 H343 C345 I346 G347 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 A 2.08 BS02 DEB A 1 M83 F84 L94 S240 I243 A244 T248 S295 F296 L396 M72 F73 L83 S229 I232 A233 T237 S284 F285 L385 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 B 2.08 BS01 HEM B 1 V93 L94 H101 R105 F112 I157 A244 G245 T248 Q252 L285 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 V88 L89 H96 R100 F107 I152 A239 G240 T243 Q247 L280 L285 R293 F316 A343 F344 G345 H349 C351 I352 G353 TGPTPADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 B 2.08 BS02 DEB B 1 M83 F84 L94 S240 I243 A244 T248 S295 F296 M78 F79 L89 S235 I238 A239 T243 S290 F291 TGPTPADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 C 2.08 BS01 HEM C 1 L94 H101 R105 F112 I157 A244 G245 T248 Q252 L285 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L366 L95 H102 R106 F113 I158 A245 G246 T249 Q253 L286 L291 R299 F322 A349 F350 G351 H355 C357 I358 G359 L367 HMTDTHTGPTPADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 C 2.08 BS02 DEB C 1 F84 L94 L179 S240 I243 A244 T248 S295 F296 L396 F85 L95 L180 S241 I244 A245 T249 S296 F297 L397 HMTDTHTGPTPADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 D 2.08 BS01 HEM D 1 V93 L94 H101 R105 F112 A244 G245 T248 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 V82 L83 H90 R94 F101 A233 G234 T237 L279 R287 F310 A337 F338 G339 H343 C345 I346 G347 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 D 2.08 BS02 DEB D 1 M83 F84 W92 L94 M178 S240 I243 A244 T248 V291 S295 F296 L396 M72 F73 W81 L83 M167 S229 I232 A233 T237 V280 S284 F285 L385 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 E 2.08 BS01 HEM E 1 V93 L94 H101 R105 F112 I157 A244 G245 T248 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 G362 V81 L82 H89 R93 F100 I145 A232 G233 T236 Q240 L278 R286 F309 A336 F337 G338 H342 C344 I345 G346 G350 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 E 2.08 BS02 DEB E 1 F84 L94 M178 I243 A244 T248 S295 L396 F72 L82 M166 I231 A232 T236 S283 L384 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 F 2.08 BS01 HEM F 1 V93 L94 H101 R105 F112 I157 A244 G245 T248 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L366 V82 L83 H90 R94 F101 I146 A233 G234 T237 Q241 L279 R287 F310 A337 F338 G339 H343 C345 I346 G347 L355 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7q89 F 2.08 BS02 DEB F 1 M83 F84 W92 L94 I243 A244 T248 S295 F296 L396 M72 F73 W81 L83 I232 A233 T237 S284 F285 L385 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDWVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 7qbl A 2.00 BS01 A0U A 1 Q19 G23 S24 C25 G64 G65 G66 Y67 L160 N161 Q19 G23 S24 C25 G64 G65 G66 Y67 L160 N161 3.4.22.38 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 7qbm A 1.88 BS01 A0U A 1 Q19 G23 S24 C25 G64 G65 G66 L160 N161 Q20 G24 S25 C26 G65 G66 G67 L161 N162 3.4.22.38 RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 7qbm P 1.88 BS01 MG P 1 S68 E69 S61 E62 3.4.22.38 DTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQK 7qbn A 1.55 BS01 9ZG A 1 Q19 G23 S24 C25 W26 E59 N60 D61 G65 G66 Y67 A134 L160 N161 L209 Q21 G25 S26 C27 W28 E61 N62 D63 G67 G68 Y69 A136 L162 N163 L211 3.4.22.38 GRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 7qbo A 1.90 BS01 9ZG A 1 Q19 G23 S24 C25 W26 E59 D61 G65 G66 Y67 A134 L160 N161 L209 Q20 G24 S25 C26 W27 E60 D62 G66 G67 Y68 A135 L161 N162 L210 3.4.22.38 RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 7qdt A 3.00 BS01 T3 A 1 F215 F218 I221 I222 A225 R228 M256 M259 R262 A263 T275 L276 S277 G290 G291 L292 I299 H381 R384 F60 F63 I66 I67 A70 R73 M101 M104 R107 A108 T120 L121 S122 G135 G136 L137 I144 H226 R229 34871063 QRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMKVE 7qe7 A 2.90 BS01 III W 1 S1311 P1322 W1386 S1023 P1034 W1098 TMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSASSHPREPLPTMFSMLHPLDEITPLVCKSSRVQYVVDHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLETEPIVPELCIDHLWTETITNIREKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPTYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGYNTDRLAWTRNFTGSDDDWEYLLNSDYHQNVESHLLNRSLCLSPSEEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITISVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSKQATEEEDDGMNDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLL 7qe7 N 2.90 BS01 ZN N 1 C221 C224 C231 C233 C196 C199 C206 C208 PGQELLVAWNTVSTGLVPPAGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQNDLQANISPEFWNAISQCENSADEPQCLLLLLDAFGLLESRLDPYLRSLELLEKWTRLGLLMGTGAQGLREEVHTMLRGVLFFSTPRTFQEMIQRLYGCFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCSSDKQQCWCRQALEQFHQLSQVLHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQDGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIVRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPAEDDSGEPEDWVPDPVDADPGRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEER 7qe7 S 2.90 BS01 ZN S 1 C378 C381 C396 C401 C43 C46 C61 C66 MFRTPLASVQKSAAQTSLKKYSRHNEFSEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCSPLPGTKKSKKNLRRL 7qe7 S 2.90 BS02 ZN S 2 C406 K408 C409 H414 C419 C71 K73 C74 H79 C84 MFRTPLASVQKSAAQTSLKKYSRHNEFSEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCSPLPGTKKSKKNLRRL 7qe7 K 2.90 BS01 III W 1 E239 Y242 Y243 C245 F247 V270 E277 A339 H342 A345 Y373 L376 E377 D401 H406 E407 F413 W444 E445 P446 N449 N450 H453 R456 K457 N478 S480 A484 Y487 S490 L491 F495 F514 T517 M518 E524 M525 E218 Y221 Y222 C224 F226 V249 E256 A318 H321 A324 Y352 L355 E356 D380 H385 E386 F392 W423 E424 P425 N428 N429 H432 R435 K436 N457 S459 A463 Y466 S469 L470 F474 F493 T496 M497 E503 M504 MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMEEPDWEMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIPESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIGCYDFDVHTMKTLKNIISPPWDFRE 7qe7 Q 2.90 BS01 III G 1 H174 Y212 Y242 Y243 G273 V276 I338 H342 A345 Y357 C367 Y373 L376 E377 F403 H406 E407 V410 F413 K443 W444 E445 P446 N449 N450 H453 R456 K457 N478 S480 T481 Y487 S490 L491 T513 F514 M518 M525 H147 Y185 Y215 Y216 G246 V249 I311 H315 A318 Y330 C340 Y346 L349 E350 F376 H379 E380 V383 F386 K416 W417 E418 P419 N422 N423 H426 R429 K430 N451 S453 T454 Y460 S463 L464 T486 F487 M491 M498 MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIPESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIGDSEAY 7qe7 C 2.90 BS01 ZN C 1 C23 C26 H56 C59 C23 C26 H56 C59 MKVKIKCWNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE 7qe7 C 2.90 BS02 ZN C 2 C34 C37 C44 H58 C34 C37 C44 H58 MKVKIKCWNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE 7qe7 C 2.90 BS03 ZN C 3 C51 H53 C73 C76 C51 H53 C73 C76 MKVKIKCWNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLHAQQVQQHCPMCRQEWKFKE 7qgi D 1.65 BS01 ZN D 1 H257 C261 H264 C279 H200 C204 H207 C222 3.1.13.- PTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHGTNLPLQLGFSTGVNLVAVPTPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFT 7qgi D 1.65 BS02 ZN D 2 C452 C477 C484 H487 C393 C412 C419 H422 3.1.13.- PTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHGTNLPLQLGFSTGVNLVAVPTPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFT 7qgi D 1.65 BS03 ZN D 3 C207 C210 C226 H229 C150 C153 C169 H172 3.1.13.- PTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHGTNLPLQLGFSTGVNLVAVPTPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFT 7qgp A 1.90 BS01 DJ8 A 1 L42 D44 F47 V50 A63 I67 Y78 E81 I108 I110 E111 F112 C113 G116 L164 D175 V178 L20 D22 F25 V28 A41 I45 Y53 E56 I83 I85 E86 F87 C88 G91 L139 D150 V153 2.7.11.1 YEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIEEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLAIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAE 7rkf A 4.00 BS01 GDP A 1 G42 E43 S44 G45 K46 S47 T48 S150 R175 R177 K269 C324 A325 T326 G39 E40 S41 G42 K43 S44 T45 S147 R172 R174 K266 C321 A322 T323 TLSAEDKAAVERSKMIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV 7rkm R 3.50 BS01 CLR R 1 V70 I73 N74 L81 C145 I149 W152 V56 I59 N60 L67 C131 I135 W138 DYDEDATPCVFTDVLNQSKPVTLFLYGVVFLFGSIGNFLVIFTITWRRRIQCSGDVYFINLAAADLLFVCTLPLWMQYLLDHNSLASVPCTLLTACFYVAMFASLCFITEIALDRYYAIVYMRYRPVKQACLFSIFWWIFAVIIAIPHFMVVTKKDNQCMTDYDYLEVSYPIILNVELMLGAFVIPLSVISYCYYRISRIVAVSQSRHKGRIVRVLIAVVLVFIIFWLPYHLTLFVDTLKLLKWISSSCEFERSLKRALILTESLAFCHCCLNPLLYVFVGTKFRQELHCLLAE 7rky A 3.80 BS01 GDP A 1 A41 G42 E43 S44 G45 K46 S47 T48 D150 S151 R176 L273 C325 A326 T327 A40 G41 E42 S43 G44 K45 S46 T47 D149 S150 R175 L265 C317 A318 T319 GCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLK 7rlv B 2.20 BS01 III P 1 H27D Y32 N34 G91 Y93 Y94 P95 F96 H31 Y37 N39 G96 Y98 Y99 P100 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 7rlv A 2.20 BS01 III P 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 Q61 E95 W100B G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 Q60 E97 W104 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 7rlv D 2.20 BS01 III R 1 H27D Y32 N34 G91 Y93 Y94 P95 F96 H31 Y37 N39 G96 Y98 Y99 P100 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rlv C 2.20 BS01 III R 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 Q61 E95 W100B G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 Q60 E97 W104 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLTYICNVNHKPSNTKVDKKVE 7rlv F 2.20 BS01 III Q 1 H27D Y32 N34 G91 Y93 Y94 P95 F96 H31 Y37 N39 G96 Y98 Y99 P100 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 7rlv E 2.20 BS01 III Q 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 E95 W100B Y100C G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 E97 W104 Y105 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 7rlw B 2.54 BS01 III P 1 H27D Y32 N34 G91 T92 Y93 Y94 F96 H31 Y37 N39 G96 T97 Y98 Y99 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 7rlw A 2.54 BS01 III P 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 E95 W100B G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 E97 W104 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 7rlw D 2.54 BS01 III R 1 Y32 N34 G91 T92 Y93 Y94 P95 F96 Y37 N39 G96 T97 Y98 Y99 P100 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rlw C 2.54 BS01 III R 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 E95 W100B G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 E97 W104 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 7rlx B 1.97 BS01 III P 1 H27D Y32 N34 G91 Y93 Y94 P95 F96 H31 Y37 N39 G96 Y98 Y99 P100 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rlx A 1.97 BS01 III P 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 E95 W100B Y100C G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 E97 W104 Y105 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 7rly B 2.67 BS01 III Q 1 H27D Y32 N34 G91 T92 Y93 Y94 F96 H31 Y37 N39 G96 T97 Y98 Y99 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rly A 2.67 BS01 III Q 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 E95 W100B G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 E97 W104 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 7rly D 2.67 BS01 III P 1 H27D Y32 N34 G91 T92 Y93 Y94 P95 F96 H31 Y37 N39 G96 T97 Y98 Y99 P100 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rly C 2.67 BS01 III P 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 E95 W100B G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 E97 W104 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 7rly F 2.67 BS01 III R 1 L27C H27D S27E Y32 N34 G91 T92 Y93 Y94 P95 F96 L30 H31 S32 Y37 N39 G96 T97 Y98 Y99 P100 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rly E 2.67 BS01 III R 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 E95 W100B G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 E97 W104 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 7rlz B 2.27 BS01 III P 1 H27D Y32 N34 G91 T92 Y93 Y94 P95 F96 H31 Y37 N39 G96 T97 Y98 Y99 P100 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rlz A 2.27 BS01 III P 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 E95 W100B G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 E97 W104 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 7rlz C 2.27 BS01 III R 1 H27D Y32 N34 G91 T92 Y93 Y94 P95 F96 H31 Y37 N39 G96 T97 Y98 Y99 P100 F101 35023832 DIVMTQTPLSLSVTIGQPASISCKSSQSLLHSNGKTYLNWLQQRPGQAPKILMYLVSKLDPGIPDRFSGSGSETDFTLKISRVEAEDLGVYYCLQGTYYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rlz D 2.27 BS01 III R 1 G31 Y32 Y33 W47 R50 D52 Y53 D54 S58 E95 W100B Y100C G29 Y30 Y31 W45 R48 D50 Y52 D53 S57 E97 W104 Y105 35023832 QLQQSGPELVKPGASVKISCKASGYSFTGYYMHWVKQSHVKSLEWIGRIDPYDGATSYNQNFKDKASLTVDKSSTTGFMELHSLTSEDSAVYYCAREGHWDGDWYFDVWGAGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 7rm0 A 2.71 BS01 III P 1 T30 N31 Y32 G33 W50 N52 S52A W95 A96 N97 G99 T30 N31 Y32 G33 W50 N52 S53 W99 A100 N101 G103 35023832 QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLKWMGWINSNTGEPTYAEEFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWANCGCAMDYWGQGTTVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVP 7rm0 B 2.71 BS01 III P 1 Y32 D91 Y92 Y38 D97 Y98 35023832 DIVMTQSPSSLTVTAGEKVSMSCKSSQSLFTSGKQKNYLTWYQQKPGQPPKLLIYWASTRNSGLPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYPFTFGSGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 7rm0 C 2.71 BS01 III Q 1 T30 N31 Y32 G33 W50 N52 S52A N53 W95 A96 N97 G99 T30 N31 Y32 G33 W50 N52 S53 N54 W99 A100 N101 G103 35023832 QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLKWMGWINSNTGEPTYAEEFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWANCGCAMDYWGQGTTVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR 7rm0 D 2.71 BS01 III Q 1 Y32 D91 Y92 Y38 D97 Y98 35023832 DIVMTQSPSSLTVTAGEKVSMSCKSSQSLFTSGKQKNYLTWYQQKPGQPPKLLIYWASTRNSGLPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYPFTFGSGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNA 7rm0 E 2.71 BS01 III R 1 N31 Y32 G33 W50 N52 S52A N53 W95 A96 N97 G99 N31 Y32 G33 W50 N52 S53 N54 W99 A100 N101 G103 35023832 QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLKWMGWINSNTGEPTYAEEFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWANCGCAMDYWGQGTTVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR 7rm0 F 2.71 BS01 III R 1 Y32 D91 Y92 Y38 D97 Y98 35023832 DIVMTQSPSSLTVTAGEKVSMSCKSSQSLFTSGKQKNYLTWYQQKPGQPPKLLIYWASTRNSGLPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYPFTFGSGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNA 7rm0 G 2.71 BS01 III S 1 T30 N31 Y32 G33 W50 N52 S52A W95 A96 N97 G99 T30 N31 Y32 G33 W50 N52 S53 W99 A100 N101 G103 35023832 QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLKWMGWINSNTGEPTYAEEFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWANCGCAMDYWGQGTTVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVP 7rm0 H 2.71 BS01 III S 1 T27D Y32 Y92 T31 Y38 Y98 35023832 DIVMTQSPSSLTVTAGEKVSMSCKSSQSLFTSGKQKNYLTWYQQKPGQPPKLLIYWASTRNSGLPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYPFTFGSGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 7rm1 A 3.19 BS01 III P 1 T30 N31 Y32 G33 W50 N52 S52A N53 T54 W95 A96 N97 C98 G99 T30 N31 Y32 G33 W50 N52 S53 N54 T55 W99 A100 N101 C102 G103 35023832 QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLKWMGWINSNTGEPTYAEEFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWANCGCAMDYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 7rm1 B 3.19 BS01 III P 1 T27D Y32 D91 Y92 T31 Y38 D97 Y98 35023832 DIVMTQSPSSLTVTAGEKVSMSCKSSQSLFTSGKQKNYLTWYQQKPGQPPKLLIYWASTRNSGLPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rm1 C 3.19 BS01 III P 1 T30 N31 Y32 G33 W50 N52 S52A N53 W95 A96 N97 G99 T30 N31 Y32 G33 W50 N52 S53 N54 W99 A100 N101 G103 35023832 QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLKWMGWINSNTGEPTYAEEFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWANCGCAMDYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 7rm1 D 3.19 BS01 III P 1 Y32 D91 Y92 F96 Y38 D97 Y98 F102 35023832 DIVMTQSPSSLTVTAGEKVSMSCKSSQSLFTSGKQKNYLTWYQQKPGQPPKLLIYWASTRNSGLPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rm3 A 2.68 BS01 III Q 1 T30 N31 Y32 G33 W50 N52 S52A N53 W95 N97 G99 T30 N31 Y32 G33 W50 N52 S53 N54 W99 N101 G103 35023832 QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLKWMGWINSNTGEPTYAEEFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWANCGCAMDYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 7rm3 B 2.68 BS01 III Q 1 D91 Y92 D97 Y98 35023832 DIVMTQSPSSLTVTAGEKVSMSCKSSQSLFTSGKQKNYLTWYQQKPGQPPKLLIYWASTRNSGLPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7rm3 C 2.68 BS01 III P 1 T30 N31 G33 W50 N52 S52A W95 A96 N97 G99 T30 N31 G33 W50 N52 S53 W99 A100 N101 G103 35023832 QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLKWMGWINSNTGEPTYAEEFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWANCGCAMDYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 7rm3 D 2.68 BS01 III P 1 K28 D91 Y92 F96 K34 D97 Y98 F102 35023832 DIVMTQSPSSLTVTAGEKVSMSCKSSQSLFTSGKQKNYLTWYQQKPGQPPKLLIYWASTRNSGLPDRFTGSGSGTDFTLTISSVQAEDLAVYYCQNDYSYPFTFGSGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 7s0u A 2.01 BS01 81X A 1 F327 K333 E435 L437 E444 S578 W579 F305 K311 E413 L415 E422 S555 W556 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSCSYLQYLEYLSQNRPLFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7s0u A 2.01 BS02 MTA A 1 P314 L315 Y324 F327 G365 G367 E392 K393 N394 S418 D419 M420 E435 L436 C449 P292 L293 Y302 F305 G343 G345 E370 K371 N372 S396 D397 M398 E413 L414 C427 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSCSYLQYLEYLSQNRPLFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7s1q A 2.78 BS01 MTA A 1 L315 Y324 F327 G365 E392 K393 S418 D419 M420 E435 L436 C449 L303 Y312 F315 G353 E380 K381 S406 D407 M408 E423 L424 C437 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7s1q A 2.78 BS02 84W A 1 Q309 S310 L312 F327 K333 E435 L436 L437 E444 V503 S578 W579 Q297 S298 L300 F315 K321 E423 L424 L425 E432 V491 S566 W567 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7s1r A 2.10 BS01 MTA A 1 P314 L315 Y324 F327 G365 E392 K393 S418 D419 M420 E435 L436 C449 P302 L303 Y312 F315 G353 E380 K381 S406 D407 M408 E423 L424 C437 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7s1r A 2.10 BS02 85E A 1 F300 Y304 Q309 S310 P311 L312 F327 K333 E435 L436 L437 E444 V503 S578 W579 F580 F288 Y292 Q297 S298 P299 L300 F315 K321 E423 L424 L425 E432 V491 S566 W567 F568 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7s1s A 2.62 BS01 MTA A 1 P314 L315 Y324 F327 G365 E392 K393 S418 D419 M420 E435 L436 C449 P302 L303 Y312 F315 G353 E380 K381 S406 D407 M408 E423 L424 C437 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7s1s A 2.62 BS02 85K A 1 F300 Y304 Q309 S310 P311 L312 V326 F327 K333 E435 L436 L437 E444 V503 S578 W579 F580 F288 Y292 Q297 S298 P299 L300 V314 F315 K321 E423 L424 L425 E432 V491 S566 W567 F568 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7ser A 2.14 BS01 97L A 1 Y304 Q309 S310 P311 L312 F327 K333 E435 L437 E444 V503 S578 W579 F580 Y292 Q297 S298 P299 L300 F315 K321 E423 L425 E432 V491 S566 W567 F568 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7ser A 2.14 BS02 MTA A 1 L315 Y324 F327 G365 G367 E392 K393 S418 D419 M420 E435 L436 C449 L303 Y312 F315 G353 G355 E380 K381 S406 D407 M408 E423 L424 C437 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7ses A 2.50 BS01 97X A 1 F300 Y304 Q309 S310 P311 L312 V326 F327 K333 E435 L437 E444 V503 S578 W579 F580 F288 Y292 Q297 S298 P299 L300 V314 F315 K321 E423 L425 E432 V491 S566 W567 F568 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7ses A 2.50 BS02 MTA A 1 P314 L315 Y324 F327 G365 G367 E392 K393 D419 M420 E435 L436 C449 P302 L303 Y312 F315 G353 G355 E380 K381 D407 M408 E423 L424 C437 2.1.1.320 35041419 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 7skl A 1.60 BS01 CA A 1 Y398 T399 K402 D405 Y190 T191 K194 D197 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skl A 1.60 BS02 CA A 2 D387 E389 D390 E395 D179 E181 D182 E187 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skl A 1.60 BS03 CA A 3 D348 D387 D390 L392 E395 D140 D179 D182 L184 E187 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skl A 1.60 BS04 ZN A 1 H352 H356 E376 H144 H148 E168 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skl C 1.60 BS01 III F 1 Q317 N321 N322 A323 F340 L343 V349 H352 E353 L407 R408 D431 H436 Q109 N113 N114 A115 F132 L135 V141 H144 E145 L199 R200 D223 H228 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skl C 1.60 BS02 CA C 1 Y398 T399 K402 D405 Y190 T191 K194 D197 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skl C 1.60 BS03 CA C 2 D387 E389 D390 E395 D179 E181 D182 E187 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skl C 1.60 BS04 CA C 3 D348 D387 D390 L392 E395 D140 D179 D182 L184 E187 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skl C 1.60 BS05 ZN C 1 H352 H356 E376 H144 H148 E168 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skl D 1.60 BS01 III F 1 I20 L22 I23 C24 H28 E29 Y30 Y31 E32 C33 G34 G35 A36 C37 D38 N39 V40 C41 L44 K49 N56 I1 L3 I4 C5 H9 E10 Y11 Y12 E13 C14 G15 G16 A17 C18 D19 N20 V21 C22 L25 K30 N37 IVLICNGGHEYYECGGACDNVCADLHIQNKTNCPIIN 7skm A 1.85 BS01 CA A 1 Y398 T399 K402 D405 Y190 T191 K194 D197 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skm A 1.85 BS02 CA A 2 D387 E389 D390 E395 D179 E181 D182 E187 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skm A 1.85 BS03 CA A 3 D348 D387 D390 L392 E395 D140 D179 D182 L184 E187 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skm A 1.85 BS04 ZN A 1 H352 H356 E376 H144 H148 E168 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGVE 7skm C 1.85 BS01 III F 1 Q317 N321 N322 A323 L343 V349 H352 E353 R408 H436 Q109 N113 N114 A115 L135 V141 H144 E145 R200 H228 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGV 7skm C 1.85 BS02 CA C 1 Y398 T399 K402 D405 Y190 T191 K194 D197 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGV 7skm C 1.85 BS03 CA C 2 D387 E389 D390 E395 D179 E181 D182 E187 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGV 7skm C 1.85 BS04 CA C 3 D348 D387 D390 L392 E395 D140 D179 D182 L184 E187 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGV 7skm C 1.85 BS05 ZN C 1 H352 H356 E376 H144 H148 E168 3.4.24.29 AAATGTGKGVLGDTKDININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGV 7skm D 1.85 BS01 III F 1 I20 L22 I23 C24 G27 H28 E29 Y30 Y31 E32 C33 G34 G35 A36 C37 D38 N39 C41 L44 K49 N56 I1 L3 I4 C5 G8 H9 E10 Y11 Y12 E13 C14 G15 G16 A17 C18 D19 N20 C22 L25 K30 N37 IVLICNGGHEYYECGGACDNVCADLHIQNKTNCPIIN 7stt A 1.60 BS01 CA A 1 D15 D16 D276 N277 D15 D16 D275 N276 35011319 MQGSRKPNIIFIMADDLGWGELGSYGNTFNETPNLDRLSAQGMRFTQAYAAAPVSPTRASIMTGQYPARVGITDFLPEDEKTDRWLDPTKYVTLNEALSASGYHTGIVGKWHLDTDFKLNKGGPKAHGFNEVIGTESEYIADGDYFFPYSKIASFDKGTANEYLTDRQCAEANAFITRNREKPFFLYLSLYSVHTRLEAPVQLVEKYKQKFDQKYGTGKAEQFFGANNVRHESAQRDNPWLAAMLESIDTGVGGIMKTLRETGLAENTIIVFFSDNGGAGKAGNNAHLRAGKTWLYEGGIREPLIVSWPGKIKGNTVNDNPVTSLDFYPTFLAAAGGKPTGGRLDGHNLMPLLRGGRASGRPLFWHYPSETGKWVNRMSSAVREGNYKLLEFYNNPRLELYDLQNDPSESHNLATDRPAETARLKKLLEDWKKEVNAEAPHLAR 7stu A 2.23 BS01 CA A 1 D15 D16 D276 N277 D15 D16 D275 N276 35011319 MQGSRKPNIIFIMADDLGWGELGSYGNTFNETPNLDRLSAQGMRFTQAYAAAPVSPTRASIMTGQYPARVGITDFLPEDEKTDRWLDPTKYVTLNEALSASGYHTGIVGKWHLDTDFKLNKGGPKAHGFNEVIGTESEYIADGDYFFPYSKIASFDKGTANEYLTDRQCAEANAFITRNREKPFFLYLSLYSVHTRLEAPVQLVEKYKQKFDQKYGTGKAEQFFGANNVRHESAQRDNPWLAAMLESIDTGVGGIMKTLRETGLAENTIIVFFSDNGGAGKAGNNAHLRAGKTWLYEGGIREPLIVSWPGKIKGNTVNDNPVTSLDFYPTFLAAAGGKPTGGRLDGHNLMPLLRGGRASGRPLFWHYPSETGKWVNRMSSAVREGNYKLLEFYNNPRLELYDLQNDPSESHNLATDRPAETARLKKLLEDWKKEVNAEAPHLAR 7stv A 2.35 BS01 CA A 1 D11 D12 D272 N273 D11 D12 D270 N271 35011319 RKPNIIFIMADDLGWGELGSYGNTFNETPNLDRLSAQGMRFTQAYAAAPVSPTRASIMTGQYPARVGITDFLPEDEKTDRWLDPTKYVTLNEALSASGYHTGIVGKWHLDTDFKLNKGGPKAHGFNEVIGTESEYIADGDYFFPYSKIASFDKGTANEYLTDRQCAEANAFITRNREKPFFLYLSLYSVHTRLEAPVQLVEKYKQKFDQKYGTGKAEQFFANNVRHESAQRDNPWLAAMLESIDTGVGGIMKTLRETGLAENTIIVFFSDNGGAGKAGNNAHLRAGKTWLYEGGIREPLIVSWPGKIKGNTVNDNPVTSLDFYPTFLAAAGGKPTGGRLDGHNLMPLLRGGRASGRPLFWHYPSETGKWVNRMSSAVREGNYKLLEFYNNPRLELYDLQNDPSESHNLATDRPAETARLKKLLEDWKKEVNAEAPHLA 7stz C 2.95 BS01 CA C 1 E11 E69 D100 Q101 D103 N104 D136 E11 E69 D100 Q101 D103 N104 D136 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS02 CA C 2 E11 D67 E69 D103 E11 D67 E69 D103 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS03 CA C 3 N102 N104 D134 D136 N143 D195 N102 N104 D134 D136 N143 D195 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS04 CA C 4 N215 N217 D246 D248 A254 N304 N215 N217 D246 D248 A254 N304 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS05 CA C 5 E232 E291 D325 V326 E328 D360 E232 E291 D325 V326 E328 D360 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS06 CA C 6 N327 E328 E358 D360 Q365 D415 N416 N327 E328 E358 D360 Q365 D415 N416 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS07 CA C 7 N435 N437 D462 D464 N468 D517 N435 N437 D462 D464 N468 D517 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS08 CA C 8 E343 E397 D433 V434 D436 D464 E343 E397 D433 V434 D436 D464 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS09 CA C 9 E343 D395 E397 D436 E343 D395 E397 D436 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS10 CA C 10 E119 R181 E182 D213 T214 D216 D248 E119 R181 E182 D213 T214 D216 D248 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS11 CA C 11 E119 D180 E182 D216 E119 D180 E182 D216 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz C 2.95 BS12 CA C 12 E232 D289 E291 E328 E232 D289 E291 E328 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGV 7stz D 2.95 BS01 CA D 1 E232 F290 E291 V326 E328 D360 E232 F290 E291 V323 E325 D357 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS02 CA D 2 E119 R181 E182 D213 T214 D216 D248 E119 R181 E182 D213 T214 D216 D248 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS03 CA D 3 N327 E328 E358 D360 Q365 D415 N324 E325 E355 D357 Q360 D406 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS04 CA D 4 E11 D67 E69 D103 N104 E11 D67 E69 D103 N104 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS05 CA D 5 E11 E69 D100 Q101 D103 N104 D136 E11 E69 D100 Q101 D103 N104 D136 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS06 CA D 6 N102 N104 D134 D136 N143 D195 N102 N104 D134 D136 N143 D195 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS07 CA D 7 N215 N217 D246 D248 A254 N304 N215 N217 D246 D248 A254 N304 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS08 CA D 8 E343 R396 E397 E340 R387 E388 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS09 CA D 9 E119 D180 R181 E182 D216 E119 D180 R181 E182 D216 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS10 CA D 10 E232 D289 E291 E328 E232 D289 E291 E325 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz D 2.95 BS11 CA D 11 E343 E397 V434 N435 D436 E340 E388 V419 N420 D421 DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFETTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFQKITYRIWRDTANWLEINPDTGAISTRREDFEHVKNSTYTALIIATDNVATGTGTLLLIVNDN 7stz M 2.95 BS01 CA M 1 S182 T184 S182 T184 DIVMTQSPSSLAMSVGQKVTMNCKSSQSLLNSSNQKNYLAWYQQKPGQSPKLLIYFTSTRGSGVPDRFIGSGSGTDFTLTISSVEAEDLADYFCQQHYRTPHTFGGGTKVEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 7tbw A 3.10 BS01 CLR A 1 W278 S279 W458 F466 Y482 W218 S219 W352 F360 Y367 CWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVARLFSDARRLLLYSQKDTSMKDMRKVLRTLQQIKKSSSKSEEMIQLGDQEVSELCGLPREKLAAAERVLRSNMDILKPILRTLNSTSPFPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTSSTQIYQAVSRIVCGHTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWRDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCEPTHLKLGVSIQNLVKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDQPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKSAISNLIRKHVSEARLVEDIGHELTYVLPAFVELFHEIDDRISSYGISETTLEEIFLKVAEESGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSKMLPVCPPGAGGLPPPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNPSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTDNKLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERVSPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIDEDEDVRRERQRILDGGGQNDILEIKELTKIYRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDQPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQ 7tbw A 3.10 BS02 ATP A 1 Y908 D910 K913 A915 N935 G936 G938 K939 T940 T941 Q980 H1089 N2044 S2046 G2047 G2048 G2074 Y763 D765 K768 A770 N790 G791 G793 K794 T795 T796 Q835 H944 N1753 S1755 G1756 G1757 G1783 CWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVARLFSDARRLLLYSQKDTSMKDMRKVLRTLQQIKKSSSKSEEMIQLGDQEVSELCGLPREKLAAAERVLRSNMDILKPILRTLNSTSPFPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTSSTQIYQAVSRIVCGHTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWRDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCEPTHLKLGVSIQNLVKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDQPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKSAISNLIRKHVSEARLVEDIGHELTYVLPAFVELFHEIDDRISSYGISETTLEEIFLKVAEESGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSKMLPVCPPGAGGLPPPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNPSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTDNKLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERVSPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIDEDEDVRRERQRILDGGGQNDILEIKELTKIYRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDQPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQ 7tbw A 3.10 BS03 ATP A 2 K1025 Q1032 S1034 G1036 Y1921 K1924 N1948 G1949 G1951 K1952 S1953 S1954 Q1993 Q2070 H2102 K880 Q887 S889 G891 Y1630 K1633 N1657 G1658 G1660 K1661 S1662 S1663 Q1702 Q1779 H1811 CWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVARLFSDARRLLLYSQKDTSMKDMRKVLRTLQQIKKSSSKSEEMIQLGDQEVSELCGLPREKLAAAERVLRSNMDILKPILRTLNSTSPFPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTSSTQIYQAVSRIVCGHTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWRDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCEPTHLKLGVSIQNLVKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDQPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKSAISNLIRKHVSEARLVEDIGHELTYVLPAFVELFHEIDDRISSYGISETTLEEIFLKVAEESGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSKMLPVCPPGAGGLPPPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNPSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTDNKLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERVSPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIDEDEDVRRERQRILDGGGQNDILEIKELTKIYRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDQPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQ 7tbw A 3.10 BS04 MG A 1 S1953 Q1993 Q2070 S1662 Q1702 Q1779 CWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVARLFSDARRLLLYSQKDTSMKDMRKVLRTLQQIKKSSSKSEEMIQLGDQEVSELCGLPREKLAAAERVLRSNMDILKPILRTLNSTSPFPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTSSTQIYQAVSRIVCGHTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWRDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCEPTHLKLGVSIQNLVKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDQPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKSAISNLIRKHVSEARLVEDIGHELTYVLPAFVELFHEIDDRISSYGISETTLEEIFLKVAEESGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSKMLPVCPPGAGGLPPPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNPSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTDNKLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERVSPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIDEDEDVRRERQRILDGGGQNDILEIKELTKIYRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDQPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQ 7tbw A 3.10 BS05 MG A 2 T940 Q980 D1057 Q1058 T795 Q835 D912 Q913 CWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVARLFSDARRLLLYSQKDTSMKDMRKVLRTLQQIKKSSSKSEEMIQLGDQEVSELCGLPREKLAAAERVLRSNMDILKPILRTLNSTSPFPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTSSTQIYQAVSRIVCGHTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWRDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCEPTHLKLGVSIQNLVKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDQPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKSAISNLIRKHVSEARLVEDIGHELTYVLPAFVELFHEIDDRISSYGISETTLEEIFLKVAEESGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSKMLPVCPPGAGGLPPPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNPSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTDNKLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERVSPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIDEDEDVRRERQRILDGGGQNDILEIKELTKIYRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDQPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQ 7tby A 4.00 BS01 CLR A 1 L272 W278 S279 A487 L155 W161 S162 A322 CWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVARLFSDARRLLLYSQKDTSMKDMRKVLRTLQQPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTSSTQIYQAVSRIVCGHPFYDNSTTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWRDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRCMEEEPTHLKLGVSIQNLVKVYLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKVSAISNLIRKHVSEARLVEDIGHELTYVLPYEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLPPPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIPDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQ 7tbz A 4.30 BS01 CLR A 1 L67 V70 F409 L65 V68 F253 CWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVARLFSDARRLLLYSQKDTSMKDMRKVLRTLQQPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTSSTQIYQAVSRIVCGHPFYDNSTTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPVCTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWRDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRCMEEEPTHLKLGVSIQNLVKVYLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKVSAISNLIRKHVSEARLVEDIGHELTYVLPYEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLPPPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIPDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQ 7tc0 A 3.10 BS01 CLR A 1 W278 S279 W458 F466 Y482 W160 S161 W298 F306 Y313 CWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVARLFSDARRLLLYSQKDTSMKDMRKVLRTLQPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTSSTQIYQAVSRIVCGHDNSTTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWRDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPCMEEEPTHLKLGVSIQNLVKVYDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLPPPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVNDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFGIPPGECFGLLGVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGSNPDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQ 7tc0 A 3.10 BS02 CLR A 2 Q24 K657 I752 Q22 K488 I583 CWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVARLFSDARRLLLYSQKDTSMKDMRKVLRTLQPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTSSTQIYQAVSRIVCGHDNSTTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPVYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWRDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPCMEEEPTHLKLGVSIQNLVKVYDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILSTHHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLPPPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSQEVNDAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVNDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFGIPPGECFGLLGVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGSNPDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQ 7thi A 1.33 BS01 PGA A 1 F22 C23 S24 E89 Y92 R100 R116 R117 N190 F21 C22 S23 E88 Y91 R99 R115 R116 N189 5.4.2.4,5.4.2.11 SKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQ 7thi B 1.33 BS01 PGA B 1 F22 C23 S24 E89 Y92 R100 R116 R117 N190 F21 C22 S23 E88 Y91 R99 R115 R116 N189 5.4.2.4,5.4.2.11 SKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVK 7thw A 2.20 BS01 CA A 1 G138 D141 E255 G6 D9 E116 NAMLLGAWDNAYIAAAMPLLLLVENIRSWPTRNAAEVRPPIVRELQYFQQHLQKKNYPQEDINHLSYLLCTYIDGIFNGNQSLLVEFHRDAWGGEDCFEHLRVYMNSPKQYREVLEFYDLIMCLGFDGKYQMIEHGAVLLMDLRSRLHTQLYGQDATQ 7thw B 2.20 BS01 CA B 1 G138 D141 E252 E255 G3 D6 E104 E107 LLGAWDNAYIAAAMPLLLLVENIRNAAEVRPPIVRELQYFQQHLQKKNYPQEDINHLSYLLCTYIDGIFNNQSLLVEFHRDAWGGEDCFEHLRVYMNSPKQYREVLEFYDLIMCLGFDGKYQMIEHGAVLLMDLRSRLHTQLYG 7thw C 2.20 BS01 CA C 1 G138 D141 E255 G6 D9 E113 NAMLLGAWDNAYIAAAMPLLLLVENIRSWPAAEVRPPIVRELQYFQQHLQKKNYPQEDINHLSYLLCTYIDGIFNGNQSLLVEFHRDAWGGEDCFEHLRVYMNSPKQYREVLEFYDLIMCLGFDGKYQMIEHGAVLLMDLRSRLHTQLYGQDATQ 7thw D 2.20 BS01 CA D 1 G138 D141 E255 G5 D8 E109 AMLLGAWDNAYIAAAMPLLLLVENIRNAAEVRPPIVRELQYFQQHLQKKNYPQEDINHLSYLLCTYIDGIFNNQSLLVEFHRDAWGGEDCFEHLRVYMNSPKQYREVLEFYDLIMCLGFDGKYQMIEHGAVLLMDLRSRLHTQLYG 7ti7 A 1.50 BS01 ADP A 1 N114 A115 K116 S117 T118 H271 N275 R306 D321 K323 G324 A329 A332 N108 A109 K110 S111 T112 H265 N269 R300 D315 K317 G318 A323 A326 6.3.2.9 GLKVVAGLGISGVSAVNFLHEQGYQVAVTDSRPTPPGHDQIPAGVKTSFGQLDQELLLQAEEIILSPGLAPQLPEIQAAIAKGISVVGDIQLLRRATDVPIVAITGSNAKSTVTTLIGLMAKDAGKKVAVGGNLGRPALDLLKDQPELLVLELSSFQLETTSHLNAEVAVVLNMSEDHLDRHGNMLGYHQAKHRIFQGAKKVVFNRDDALSRPLVPDTTPMQSFGLNAPDLNQYGVLRDADGTLWLARGLQRLIKSSDLYIQGMHNVANALACLALGEAIGLPMESMLETLKQFKGLEHRCEYVKTVHDVRYYNDSKGTNVGATLAAIDGLGAAIEVKKGKVALILGGQGKGQDFGPLRSSIEKYAKVVVLIGEDAPVIEQAIQGATKILHAATLKEAVELCQRETQAEDVVLLSPACASFDMFKSYNDRGQQFVACVNSLV 7ti7 A 1.50 BS02 CA A 1 S117 E158 K323 S111 E152 K317 6.3.2.9 GLKVVAGLGISGVSAVNFLHEQGYQVAVTDSRPTPPGHDQIPAGVKTSFGQLDQELLLQAEEIILSPGLAPQLPEIQAAIAKGISVVGDIQLLRRATDVPIVAITGSNAKSTVTTLIGLMAKDAGKKVAVGGNLGRPALDLLKDQPELLVLELSSFQLETTSHLNAEVAVVLNMSEDHLDRHGNMLGYHQAKHRIFQGAKKVVFNRDDALSRPLVPDTTPMQSFGLNAPDLNQYGVLRDADGTLWLARGLQRLIKSSDLYIQGMHNVANALACLALGEAIGLPMESMLETLKQFKGLEHRCEYVKTVHDVRYYNDSKGTNVGATLAAIDGLGAAIEVKKGKVALILGGQGKGQDFGPLRSSIEKYAKVVVLIGEDAPVIEQAIQGATKILHAATLKEAVELCQRETQAEDVVLLSPACASFDMFKSYNDRGQQFVACVNSLV 7tll A 1.63 BS01 4WI A 1 H41 M49 F140 N142 G143 C145 H163 H164 M165 E166 L167 P168 H172 D187 R188 Q189 T190 Q192 H41 M49 F140 N142 G143 C145 H163 H164 M165 E166 L167 P168 H172 D187 R188 Q189 T190 Q192 3.4.22.69 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRHNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 7tll B 1.63 BS01 4WI B 1 H41 M49 F140 N142 G143 S144 C145 H163 H164 M165 E166 L167 P168 H172 Q189 T190 Q192 H41 M49 F140 N142 G143 S144 C145 H163 H164 M165 E166 L167 P168 H172 Q189 T190 Q192 3.4.22.69 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRHNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGV 7vw1 A 2.49 BS01 CU1 A 1 M67 H70 H71 M36 H39 H40 SSASSQEYMAGMKNMHEKMMAAVNESNPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQMNKWLDSHK 7vw1 B 2.49 BS01 CU1 B 1 M67 H70 H71 M43 H46 H47 MKMSDMHSSASSQEYMAGMKNMHEKMMAAVNESNPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQMNKWLDSHK 7vw1 B 2.49 BS02 CU1 B 2 H47 M51 H23 M27 MKMSDMHSSASSQEYMAGMKNMHEKMMAAVNESNPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQMNKWLDSHK 7vw2 B 2.19 BS01 CU B 1 H47 M51 H16 M20 SSASSQEYMAGMKNMHEKMMAAVNESNPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQMNKWLDSHK 7vw2 B 2.19 BS02 CU B 2 M50 H70 M19 H39 SSASSQEYMAGMKNMHEKMMAAVNESNPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAQDIIKAQKGEIEQMNKWLDSHK 7w7l A 3.00 BS01 NUC C 1 R52 Y55 C57 E58 H140 T142 K143 Q254 Q284 R20 Y23 C25 E26 H108 T110 K111 Q222 Q252 ETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYY 7w7l A 3.00 BS02 NUC D 1 R52 R54 S61 H62 G63 K75 K144 K221 R20 R22 S29 H30 G31 K43 K112 K189 ETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYY 7w7l B 3.00 BS01 NUC C 1 R52 R54 S61 H62 G63 K75 K144 K221 R19 R21 S28 H29 G30 K42 K111 K188 TADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYP 7w7l B 3.00 BS02 NUC D 1 R52 Y55 C57 E58 T142 K143 P223 Q254 K255 Q284 R19 Y22 C24 E25 T109 K110 P190 Q221 K222 Q251 TADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYP 7wc4 A 3.20 BS01 CLR A 1 T342 C353 V357 I358 L361 T311 C322 V326 I327 L330 SLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAGDILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc4 A 3.20 BS02 CLR A 2 I89 A90 I93 M97 Y394 Y399 I23 A24 I27 M31 Y363 Y368 SLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAGDILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc4 A 3.20 BS03 CLR A 3 S100 L122 S34 L56 SLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAGDILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc4 A 3.20 BS04 MG A 1 E1008 D1012 E207 D211 SLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAGDILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc4 A 3.20 BS05 SRO A 1 W151 D155 V156 F339 L362 W85 D89 V90 F308 L331 SLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAGDILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc5 A 3.20 BS01 MG A 1 E1008 D1012 E200 D204 SLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAGDILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc5 A 3.20 BS02 CLR A 1 I341 T342 M345 C353 N354 I358 L361 F365 I303 T304 M307 C315 N316 I320 L323 F327 SLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAGDILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc5 A 3.20 BS03 CLR A 2 S100 M114 L122 S34 M48 L56 SLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAGDILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc5 A 3.20 BS04 91Q A 1 W151 D155 L228 F339 N363 W85 D89 L155 F301 N325 SLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAGDILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc6 A 2.60 BS01 MG A 1 E1008 D1012 E193 D197 KNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc6 A 2.60 BS02 CLR A 1 I341 T342 M345 C353 N354 I358 L361 F365 I295 T296 M299 C307 N308 I312 L315 F319 KNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc6 A 2.60 BS03 7LD A 1 S131 W151 I152 D155 V156 S159 V235 G238 W336 F339 F340 N343 V366 Y370 S58 W78 I79 D82 V83 S86 V155 G158 W290 F293 F294 N297 V320 Y324 KNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc7 A 2.60 BS01 MG A 1 E1008 D1012 E196 D200 LQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc7 A 2.60 BS02 CLR A 1 I341 T342 M345 C353 N354 V357 I358 L361 F365 I298 T299 M302 C310 N311 V314 I315 L318 F322 LQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc7 A 2.60 BS03 H8G A 1 W151 I152 D155 V156 S159 L229 G238 S242 W336 F339 F340 N343 V366 Y370 W81 I82 D85 V86 S89 L152 G161 S165 W293 F296 F297 N300 V323 Y327 LQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc8 A 2.45 BS01 MG A 1 E1008 D1012 E198 D202 HLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPISRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc8 A 2.45 BS02 CLR A 1 I341 T342 C353 N354 V357 I358 L361 I300 T301 C312 N313 V316 I317 L320 HLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPISRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc8 A 2.45 BS03 92S A 1 W151 D155 V156 S159 T160 I163 L228 L229 S242 F243 F332 W336 F339 F340 N343 L362 N363 V366 Y370 W82 D86 V87 S90 T91 I94 L153 L154 S167 F168 F291 W295 F298 F299 N302 L321 N322 V325 Y329 HLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPISRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc8 A 2.45 BS04 CLR A 2 I206 P209 F213 I131 P134 F138 HLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPISRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc8 A 2.45 BS05 CLR A 3 I93 I96 M97 S100 L101 M121 I24 I27 M28 S31 L32 M52 HLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPISRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc8 A 2.45 BS06 CLR A 4 V99 S100 Q106 Y111 M114 S115 I118 L122 R189 F193 I196 V30 S31 Q37 Y42 M45 S46 I49 L53 R114 F118 I121 HLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPISRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc9 A 2.50 BS01 MG A 1 E1008 D1012 E196 D200 LQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc9 A 2.50 BS02 CLR A 1 P338 I341 T342 M345 C353 V357 I358 L361 P295 I298 T299 M302 C310 V314 I315 L318 LQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc9 A 2.50 BS03 CLR A 2 A90 I93 M97 Y394 Y399 A20 I23 M27 Y351 Y356 LQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wc9 A 2.50 BS04 93F A 1 D155 S159 L228 L229 F243 F332 W336 F339 F340 N343 L362 V366 Y370 D85 S89 L151 L152 F166 F289 W293 F296 F297 N300 L319 V323 Y327 LQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQNPSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDADILVGQIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLNSAVNPLVYTLFNKTYRSAFSRYIQCQYKE 7wk8 A 3.61 BS01 III B 1 K528 S530 T531 N532 L533 V534 V539 N540 N542 F543 N544 D578 P579 Q580 S591 F592 G593 K1 S3 T4 N5 L6 V7 V12 N13 N15 F16 N17 D51 P52 Q53 S64 F65 G66 KKSTNLVKNKCVNFNFNGLKGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFG 7wk8 C 3.61 BS01 III B 1 R31 S54 R31 S54 QVQLQQPGAELVRPGASVKLSCKASGYSFTRFWMNWVKQRPGQGLEWIGMIHPSDSETRLNQKFKDKATLTVDKSSTTAYMQLSSPTSEDSAVYYCARKDYDYDAWFAYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKI