6jz4 A 1.71 BS01 EVA A 1 D167 H335 N417 E418 N472 Y474 Y478 E512 W557 R570 N574 K576 D166 H334 N396 E397 N451 Y453 Y457 E491 W536 R549 N553 K555 Q6W7J7 LEYSELYPIQNEYRMMQSLDGMWKFQFDPEEIGKKSGWENGLPAPVSMPVPSSFADFFTDHKERDYCGDFWYETEFYLPAEWRNKKIWLRFGSITHRGTVYCNGMEITSHEGGFLPVLADISTVAKPGQVNQVVVKINNELNETSLPCGATKILNNGRKLAKPYFDFFNYSGLQRSVWVIALPEESVKDYSVDYELCGTDALVKYEVVTTGEHPVIVRLLDAEGELVAETEGKEGILQVANARLWEVRNAYLYQIVILITDGNGVLDEYREKIGIRTVRIEGTKILLNDRPVYLKGFGKHEDFPILGRGFHWGIVKRDFECLKWTNANCFRTSHYPYAEEWYQFADEEGFLIIDEVPAVGMALTVPELLKSHIADTEEMITRDKNHPSVIAWSLFNEPETITDYAYEYFKEVFAAAETYDFQSRPMTGAFEKNSKPELCKCYPLCDFICLNRYYGWYISGGPEIEEAEELFRDEMDRWKAKELNVPFVFTEFGTDTMAGLHKLPSIMWSEEYQKEYLEMNFRVFDSYEFVQGELAWNFADFQTTEGIMRVDGNHKGVFTRDRQPKAAAVVFKDRWE 6k52 A 1.68 BS01 CA A 1 D2 T280 D3 T281 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k52 A 1.68 BS02 CA A 2 D260 D263 D261 D264 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 A 1.91 BS03 BGC A 1 D49 R50 E360 G407 D50 R51 E361 G408 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 A 1.91 BS04 BGC A 2 W47 D49 Y85 S97 K356 P357 E360 K377 G407 W48 D50 Y86 S98 K357 P358 E361 K378 G408 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 A 1.91 BS05 GLC A 1 Y85 S97 D140 A225 W330 K356 D362 Y86 S98 D141 A226 W331 K357 D363 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 A 1.91 BS06 BGC A 3 D91 S93 A94 D140 H186 W189 N226 W330 D92 S94 A95 D141 H187 W190 N227 W331 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 A 1.91 BS07 BGC A 4 S93 N148 H186 G188 W189 N226 G328 W330 Y391 S94 N149 H187 G189 W190 N227 G329 W331 Y392 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 A 1.91 BS08 BGC A 5 T147 G188 W189 W192 N195 H326 G328 T148 G189 W190 W193 N196 H327 G329 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 B 1.91 BS03 BGC B 1 D91 S93 D140 H186 W189 N226 W330 D92 S94 D141 H187 W190 N227 W331 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 B 1.91 BS04 BGC B 2 S93 N148 H186 G188 W189 G328 W330 Y391 S94 N149 H187 G189 W190 G329 W331 Y392 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 B 1.91 BS05 BGC B 3 T147 W189 W192 N195 H326 T148 W190 W193 N196 H327 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 C 1.91 BS03 BGC C 1 S93 D140 H186 W189 N226 W330 S94 D141 H187 W190 N227 W331 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k54 C 1.91 BS05 BGC C 3 T147 G188 W189 W192 N195 H326 T148 G189 W190 W193 N196 H327 3.2.1.91 MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPDSLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 A 2.88 BS01 MG A 1 P236 D260 D263 P237 D261 D264 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 A 2.88 BS02 MG A 2 D2 T280 D350 D3 T281 D351 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 A 2.88 BS04 BGC A 2 W47 D49 S97 K356 P357 E360 K377 G407 W48 D50 S98 K357 P358 E361 K378 G408 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 A 2.88 BS05 BGC A 3 Y85 S97 A225 W330 K356 D362 Y86 S98 A226 W331 K357 D363 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 A 2.88 BS06 BGC A 4 D91 S93 A94 N226 W330 D92 S94 A95 N227 W331 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 A 2.88 BS07 BGC A 5 N148 H186 G188 W189 N226 G328 W330 N149 H187 G189 W190 N227 G329 W331 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 A 2.88 BS08 BGC A 6 T147 G188 W189 N195 H326 G328 T148 G189 W190 N196 H327 G329 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 A 2.88 BS09 BGC A 7 W192 N195 E254 W193 N196 E255 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 B 2.88 BS04 BGC B 2 W47 D49 Y85 S97 K356 P357 E360 K377 A406 G407 W48 D50 Y86 S98 K357 P358 E361 K378 A407 G408 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 B 2.88 BS05 BGC B 3 W47 Y85 W330 K356 D362 W48 Y86 W331 K357 D363 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 B 2.88 BS07 BGC B 5 S93 N148 H186 G188 W189 N226 W330 Y391 S94 N149 H187 G189 W190 N227 W331 Y392 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 B 2.88 BS09 BGC B 7 W192 E254 W193 E255 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 C 2.88 BS02 MG C 2 D2 T280 I281 G282 D350 D3 T281 I282 G283 D351 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 C 2.88 BS03 BGC C 1 D49 E360 G407 D50 E361 G408 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 C 2.88 BS06 BGC C 4 D91 S93 A94 W189 N226 W330 D92 S94 A95 W190 N227 W331 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k55 C 2.88 BS07 BGC C 5 S93 N148 H186 G188 W189 Y391 S94 N149 H187 G189 W190 Y392 3.2.1.- MLDNPFIGAIGYVNPDWATNVISQANQTADPTLAAQMRKVATYSTAVWLDRIAAITAGRGLRGHLDEALRQMQQAGQPVVITLVIYDLPNRDCSAAASNGELLVAQNGLARYKAEFIDPIVAILSDPRYAGLRIVTIIEPASLPNLVTNLSIPACAEAQNAYIEGIRYAVNRLRTIPNVYIYLDIAHSGWLGWDNNFNGAVNLYTQVVQGMDQGFNSIDGFITNVANYTPLEEPYLPDPNLTIAGQPVRSASFYEWNPYFDELDYALALRNAFIGRGFPSTIGMLIDTSRNGWGGCSYGRCRPTGPSSDTSSVNAYVDGSRVDRRYHRGNWCNQAGGIGERPQAAPRSGIDAYVWVKPPGESDGVSQPGIVDPDDPNKKFDPMCDPNGQSRYNSAYPTGALPNAPHAGRWFPQQFEILVRNAYPPIQP 6k6i A 1.90 BS01 RET A 1 F72 W75 T79 L82 M107 G111 Y126 S129 C130 Y133 W170 Y173 P174 W177 D200 S203 K204 F72 W75 T79 L82 M107 G111 Y126 S129 C130 Y133 W170 Y173 P174 W177 D200 S203 K204 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVINGRPTYWVRFVTWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTPKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLE 6k6i A 1.90 BS02 CL A 1 I45 A46 T74 S78 K204 I45 A46 T74 S78 K204 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVINGRPTYWVRFVTWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTPKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLE 6k6i A 1.90 BS03 CL A 2 H152 R154 S155 H152 R154 S155 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVINGRPTYWVRFVTWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTPKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLE 6k6j A 2.50 BS02 BR A 1 A46 L49 T74 W75 S78 K204 A46 L49 T74 W75 S78 K204 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVINGRPTYWVRFVTWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTPKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLE 6k6k A 2.20 BS02 RET A 1 F72 W75 T79 L82 M107 Y126 S129 C130 Y133 W170 Y173 P174 W177 S203 K204 F72 W75 T79 L82 M107 Y126 S129 C130 Y133 W170 Y173 P174 W177 S203 K204 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVIAGRPTYWVRFVTWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTAKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLE 6khy A 3.01 BS01 NUC E 1 Y81 L82 V84 S87 F92 G117 A118 N146 K147 G229 Y84 L85 V87 S90 F95 G120 A121 N149 K150 G232 3.1.21.- P0C9C6 32194979 GGGMFGAFVSHRLWSDSGCTTTCITNSIANYVAFGEQIGFPFKSAQVFIAGPRKAVINIQEDDKVELLKMIVKHNLWVVAHGTYLDVPWSRRSAFVTHFIQQELLICKEVGIKGLVLHLGAVEPELIVEGLKKIKPVEGVVIYLETPHNKHHTYKYSTMEQIKELFLRIRNTRLKQIGLCIDTAHIWSSGVNISSYNDAGQWLRSLENIHSVIPPSHIMFHLNDAATECGSGIDRHASLFEGMIWKSYSHKIKQSGLYCFVEYITRHQCPAILERNLGSSMQLQTALTAEFTTLKSLLK 6khy A 3.01 BS02 NUC F 1 R50 Y81 D231 R232 H233 R53 Y84 D234 R235 H236 3.1.21.- P0C9C6 32194979 GGGMFGAFVSHRLWSDSGCTTTCITNSIANYVAFGEQIGFPFKSAQVFIAGPRKAVINIQEDDKVELLKMIVKHNLWVVAHGTYLDVPWSRRSAFVTHFIQQELLICKEVGIKGLVLHLGAVEPELIVEGLKKIKPVEGVVIYLETPHNKHHTYKYSTMEQIKELFLRIRNTRLKQIGLCIDTAHIWSSGVNISSYNDAGQWLRSLENIHSVIPPSHIMFHLNDAATECGSGIDRHASLFEGMIWKSYSHKIKQSGLYCFVEYITRHQCPAILERNLGSSMQLQTALTAEFTTLKSLLK 6khy B 3.01 BS02 NUC H 1 Y81 D231 R232 H233 Y84 D234 R235 H236 3.1.21.- P0C9C6 32194979 GGGMFGAFVSHRLWSDSGCTTTCITNSIANYVAFGEQIGFPFKSAQVFIAGPRKAVINIQEDDKVELLKMIVKHNLWVVAHGTYLDVPWSRRSAFVTHFIQQELLICKEVGIKGLVLHLGAVEPELIVEGLKKIKPVEGVVIYLETPHNKHHTYKYSTMEQIKELFLRIRNTRLKQIGLCIDTAHIWSSGVNISSYNDAGQWLRSLENIHSVIPPSHIMFHLNDAATECGSGIDRHASLFEGMIWKSYSHKIKQSGLYCFVEYITRHQCPAILERNLGSSMQLQTALTAEFTTLKSLLK 6khy C 3.01 BS02 NUC F 1 Y81 L82 V84 A118 N146 K147 H148 H149 G229 Y84 L85 V87 A121 N149 K150 H151 H152 G232 3.1.21.- P0C9C6 32194979 GGGMFGAFVSHRLWSDSGCTTTCITNSIANYVAFGEQIGFPFKSAQVFIAGPRKAVINIQEDDKVELLKMIVKHNLWVVAHGTYLDVPWSRRSAFVTHFIQQELLICKEVGIKGLVLHLGAVEPELIVEGLKKIKPVEGVVIYLETPHNKHHTYKYSTMEQIKELFLRIRNTRLKQIGLCIDTAHIWSSGVNISSYNDAGQWLRSLENIHSVIPPSHIMFHLNDAATECGSGIDRHASLFEGMIWKSYSHKIKQSGLYCFVEYITRHQCPAILERNLGSSMQLQTALTAEFTTLKSLLK 6l7v A 2.20 BS01 MN A 1 E42 E44 E210 E25 E27 E150 Q4E2I1 32381506 DAEQRAVAKALFDAVNKHLSNPFIEVEMRLGQFKANFTACVSTEDYERIKTYLMTEMENSSMTRSVTHDVWRHTYATDENGNPTRCVSIVRKKRLFVKNIVVPLGAYNLRFAVSTETPTRLKDRLSITDGMFRYDMTQVTEKGVLMHEVEIEGVFSSKQLTESWLEELLRRAMRLATLRT 6l7v A 2.20 BS02 3PO A 1 E42 R46 R118 K138 E162 K182 R184 E25 R29 R72 K92 E116 K122 R124 Q4E2I1 32381506 DAEQRAVAKALFDAVNKHLSNPFIEVEMRLGQFKANFTACVSTEDYERIKTYLMTEMENSSMTRSVTHDVWRHTYATDENGNPTRCVSIVRKKRLFVKNIVVPLGAYNLRFAVSTETPTRLKDRLSITDGMFRYDMTQVTEKGVLMHEVEIEGVFSSKQLTESWLEELLRRAMRLATLRT 6l7v A 2.20 BS03 IOD A 1 Q49 C82 S84 Q32 C40 S42 Q4E2I1 32381506 DAEQRAVAKALFDAVNKHLSNPFIEVEMRLGQFKANFTACVSTEDYERIKTYLMTEMENSSMTRSVTHDVWRHTYATDENGNPTRCVSIVRKKRLFVKNIVVPLGAYNLRFAVSTETPTRLKDRLSITDGMFRYDMTQVTEKGVLMHEVEIEGVFSSKQLTESWLEELLRRAMRLATLRT 6l7v A 2.20 BS04 IOD A 2 M235 R236 T239 M173 R174 T177 Q4E2I1 32381506 DAEQRAVAKALFDAVNKHLSNPFIEVEMRLGQFKANFTACVSTEDYERIKTYLMTEMENSSMTRSVTHDVWRHTYATDENGNPTRCVSIVRKKRLFVKNIVVPLGAYNLRFAVSTETPTRLKDRLSITDGMFRYDMTQVTEKGVLMHEVEIEGVFSSKQLTESWLEELLRRAMRLATLRT 6l7w A 2.60 BS01 MN A 1 E42 E44 E210 E212 E25 E27 E153 E155 Q4E2I1 32381506 DAEQRAVAKALFDAVNKHLSNPFIEVEMRLGQFFTACVSTEDYERIKTYLMTEMENSSMTRSVTHDVSLRGWRHTYATDENGNPTRCVSIVRKKRLFVKNIVVPLGAYNLRFAVSTETPGHTRLKDRLSITDGMFRYDMTQVTEKGVLMHEVEIEGVFSSHEKQLTESWLEELLRRAMRLATLRT 6l7w B 2.60 BS01 MN B 1 E42 E44 E210 E212 E23 E25 E148 E150 Q4E2I1 32381506 EQRAVAKALFDAVNKHLSNPFIEVEMRLGQFKFTACVSTEDYERIKTYLMTEMENSSMTRSVTHDVSLGWRHTYATDENGNPTRCVSIVRKKRLFVKNIVVPLGAYNLRFAVSTETPRLKDRLSITDGMFRYDMTQVTEKGVLMHEVEIEGVFEKQLTESWLEELLRRAMRLATLRT 6l7x A 2.39 BS01 E7R A 1 L114 R115 W117 H119 I135 F169 L76 R77 W79 H81 I97 F131 Q4E2I1 32381506 DAEQRAVAKALFDAVNKHLSNPFIEVEMRLGQFKVEEDANFTACVSTEDYERIKTYLMTEMENSSMTRSVTHDVSLRGWRHTYATDENGNPTRCVSIVRKKRLFVKNIVVPLGAYNLRFAVSTETPGDLRFSGAGPRAGHTRLKDRLSITDGMFRYDMTQVTEKGVLMHEVEIEGVFSSHEKQLTESWLEELLRRAMRLATLR 6l7y A 2.51 BS01 JJY A 1 L114 W117 H119 I135 G165 D166 F169 L76 W79 H81 I97 G127 D128 F131 Q4E2I1 32381506 DAEQRAVAKALFDAVNKHLSNPFIEVEMRLGQFKVEEDANFTACVSTEDYERIKTYLMTEMENSSMTRSVTHDVSLRGWRHTYATDENGNPTRCVSIVRKKRLFVKNIVVPLGAYNLRFAVSTETPGDLRFSGAGPRAGHTRLKDRLSITDGMFRYDMTQVTEKGVLMHEVEIEGVFSSHEKQLTESWLEELLRRAMRLATLR 6lqe A 1.90 BS01 III P 1 S683 A685 G686 D687 W688 N690 W697 F711 Y714 A715 G719 L720 Y722 S9 A11 G12 D13 W14 N16 W23 F37 Y40 A41 G45 L46 Y48 Q6NQ79 32358072 ECCLICRSSTAGDWVNCGSCGEWAHFGCDRRPGLGAFKDYAKTDGLEYVCPNCSV 6lqe A 1.90 BS02 ZN A 1 C691 C694 C724 C727 C17 C20 C50 C53 Q6NQ79 32358072 ECCLICRSSTAGDWVNCGSCGEWAHFGCDRRPGLGAFKDYAKTDGLEYVCPNCSV 6lqe A 1.90 BS03 ZN A 2 C677 C680 H699 C702 C3 C6 H25 C28 Q6NQ79 32358072 ECCLICRSSTAGDWVNCGSCGEWAHFGCDRRPGLGAFKDYAKTDGLEYVCPNCSV 6lqf A 1.50 BS01 III P 1 E615 S618 R619 V624 G627 Q633 D673 E675 A685 G686 D687 W688 V689 N690 W697 F711 Y714 A715 G719 L720 Y722 E61 S64 R65 V70 G73 Q79 D119 E121 A131 G132 D133 W134 V135 N136 W143 F157 Y160 A161 G165 L166 Y168 Q6NQ79 32358072 KKHDCGRAHIQVCSEEEFLRDVMQFLLIRGHTRLVPPGGLAEFPDAVLNSKRLDLFNLYREVVSRGGFHVGNGINWKGQVFSKMRNHTLTNRMTGVGNTLKRHYETYLLEYEYAHDDVDGECCLICRSSTAGDWVNCGSCGEWAHFGCDRRPGLGAFKDYAKTDGLEYVCPNCSV 6lqf A 1.50 BS02 NUC B 1 A600 V601 L602 N603 S604 R646 T648 A46 V47 L48 N49 S50 R92 T94 Q6NQ79 32358072 KKHDCGRAHIQVCSEEEFLRDVMQFLLIRGHTRLVPPGGLAEFPDAVLNSKRLDLFNLYREVVSRGGFHVGNGINWKGQVFSKMRNHTLTNRMTGVGNTLKRHYETYLLEYEYAHDDVDGECCLICRSSTAGDWVNCGSCGEWAHFGCDRRPGLGAFKDYAKTDGLEYVCPNCSV 6lqf A 1.50 BS03 NUC C 1 N626 I628 N629 W630 K631 T648 G651 N652 K655 K716 T717 N72 I74 N75 W76 K77 T94 G97 N98 K101 K162 T163 Q6NQ79 32358072 KKHDCGRAHIQVCSEEEFLRDVMQFLLIRGHTRLVPPGGLAEFPDAVLNSKRLDLFNLYREVVSRGGFHVGNGINWKGQVFSKMRNHTLTNRMTGVGNTLKRHYETYLLEYEYAHDDVDGECCLICRSSTAGDWVNCGSCGEWAHFGCDRRPGLGAFKDYAKTDGLEYVCPNCSV 6lqf A 1.50 BS04 ZN A 1 H557 C559 D575 H669 H3 C5 D21 H115 Q6NQ79 32358072 KKHDCGRAHIQVCSEEEFLRDVMQFLLIRGHTRLVPPGGLAEFPDAVLNSKRLDLFNLYREVVSRGGFHVGNGINWKGQVFSKMRNHTLTNRMTGVGNTLKRHYETYLLEYEYAHDDVDGECCLICRSSTAGDWVNCGSCGEWAHFGCDRRPGLGAFKDYAKTDGLEYVCPNCSV 6lql A 1.80 BS01 FAD A 1 I12 G13 G15 P16 S17 E36 A37 K38 G43 R44 T45 F59 G60 G61 Q62 W63 P236 V237 A264 A265 A269 M273 L295 K297 F342 W386 W391 A395 P396 G423 T424 G432 Y433 I434 A437 I9 G10 G12 P13 S14 E33 A34 K35 G40 R41 T42 F56 G57 G58 Q59 W60 P233 V234 A261 A262 A266 M270 L292 K294 F339 W383 W388 A392 P393 G420 T421 G429 Y430 I431 A434 32203655 QTDADVIVIGAGPSGSYAAKLLHDQGVRVKLVEAKDRVGGRTWSTKSDAPGGPIDFGGQWIGETHVLLPELGAELGLETVSSVKPGNDLFVFNGDVEVGEEDQVPSGASWAGELSRSFELLDEVGTRLGWAAPWASEHVGELDSMTVAQWLEQNVQSSEVRLIHEVMVNILNGASTTEVSMAYWAYFVHQGEGIESLIGTRSGAQVAWFIGGMGQVTELIADKLGDDVHLNWPVTRIEQDPTGVTVFSGERRLRASFAILAAPPSAGSRMIFDPPLPPKRAQLQARAPMGRLAKIQVRYDEPFWQERGLSGAAFECGDLAFWLFDGSKPTDSLATIVGFIGGKHLDAWHALSPNEREKRFIEILVNNFGDKARDVRYVHETDWTVQPWTGGAPVTFMPTGLLSSAGSALREPVDRLHFAGTEAAPMWSGYIEGALRAGKIAAGDVLARLA 6lql A 1.80 BS02 F0C A 1 W63 I173 L174 L200 I201 G202 T203 Q208 L295 W325 F327 F342 P396 Y433 W60 I170 L171 L197 I198 G199 T200 Q205 L292 W322 F324 F339 P393 Y430 32203655 QTDADVIVIGAGPSGSYAAKLLHDQGVRVKLVEAKDRVGGRTWSTKSDAPGGPIDFGGQWIGETHVLLPELGAELGLETVSSVKPGNDLFVFNGDVEVGEEDQVPSGASWAGELSRSFELLDEVGTRLGWAAPWASEHVGELDSMTVAQWLEQNVQSSEVRLIHEVMVNILNGASTTEVSMAYWAYFVHQGEGIESLIGTRSGAQVAWFIGGMGQVTELIADKLGDDVHLNWPVTRIEQDPTGVTVFSGERRLRASFAILAAPPSAGSRMIFDPPLPPKRAQLQARAPMGRLAKIQVRYDEPFWQERGLSGAAFECGDLAFWLFDGSKPTDSLATIVGFIGGKHLDAWHALSPNEREKRFIEILVNNFGDKARDVRYVHETDWTVQPWTGGAPVTFMPTGLLSSAGSALREPVDRLHFAGTEAAPMWSGYIEGALRAGKIAAGDVLARLA 6lvb A 2.80 BS01 FE A 1 Y399 Y440 H519 E521 N547 Y399 Y440 H519 E521 N547 3.5.1.56 I6NT79 32452120 MKDIAIRGYCDRPSVATGETIRFYVSANETRGTFDAELVRLIHGDSNPAGPGYKEEAIKSDLEGQYPARFQRTQFGSYVEVADPDAGLQPDGAFSVHLFLWSTTPSRGRQGIASRWNDERQSGWNLAIEDGRVVFTIGDGSGATSSVVSDRPLFQQIWYSITGVYDPEKKQLRLYQKSVVNRTNSRFGLVVPLDSDCAVSADATVKAADSETSLLIAGLGEAAAQDGRTWCIAHYNGKVDAPKIYGCALGQDDAEKLSRGEIVRPISRLAHWDFSAGIGLNGIPTDHVVDASGYGHHGRCMNQPSRGSTGWNWDGHEENFIHCPEQYGALWFHEDCLDDCRWEKDFEFTVPEGLKSDFYAVKIRYEDTEDYIPFFVLPPRGTATAPILVIASTLSYLAYANEQIMHKADIGQAVAGHTPVLNENDVELHKNLSYYGLSTYDGHIDGRGVQYTSWRRPIMNLRPKHRQGFGSIWELPADLHLIDWLNHNGFEYDVATEHDLNDQGAELLRRYKVVLTGSHPEYQTWANADAWEDYLADGGRGMYLAANGMYWIVEVHPEKPWVMEVRKELGVTAWEAPPGEYHYSTNGRRGGRFRGRARATQKIWGTGMSSFGFDHSGYFVQMPDSQDERVAWIMEGIDPEERIGDGGLVGGGAGGYELDRYDLALGTPPNTLLLASSVEHSVVYTVIPDDKAFPHPGMNGGEHPFVRADITYFSTANGGGMFATSSISWLGSLSWNDYDNNVSKMTKNVLNQFIKDEPAPRV 6lvc A 3.00 BS01 FE A 1 Y399 Y440 H519 E521 Y399 Y440 H519 E521 3.5.1.56 I6NT79 32452120 MKDIAIRGYCDRPSVATGETIRFYVSANETRGTFDAELVRLIHGDSNPAGPGYKEEAIKSDLEGQYPARFQRTQFGSYVEVADPDAGLQPDGAFSVHLFLWSTTPSRGRQGIASRWNDERQSGWNLAIEDGRVVFTIGDGSGATSSVVSDRPLFQQIWYSITGVYDPEKKQLRLYQKSVVNRTNSRFGLVVPLDSDCAVSADATVKAADSETSLLIAGLGEAAAQDGRTWCIAHYNGKVDAPKIYGCALGQDDAEKLSRGEIVRPISRLAHWDFSAGIGLNGIPTDHVVDASGYGHHGRCMNQPSRGSTGWNWDGHEENFIHCPEQYGALWFHEDCLDDCRWEKDFEFTVPEGLKSDFYAVKIRYEDTEDYIPFFVLPPRGTATAPILVIASTLSYLAYANEQIMHKADIGQAVAGHTPVLNENDVELHKNLSYYGLSTYDGHIDGRGVQYTSWRRPIMNLRPKHRQGFGSIWELPADLHLIDWLNHNGFEYDVATEHDLNDQGAELLRRYKVVLTGSHPEYQTWANADAWEDYLADGGRGMYLAANGMYWIVEVHPEKPWVMEVRKELGVTAWEAPPGEYHYSTNGRRGGRFRGRARATQKIWGTGMSSFGFDHSGYFVQMPDSQDERVAWIMEGIDPEERIGDGGLVGGGAGGYELDRYDLALGTPPNTLLLASSVEHSVVYTVIPDDKAFPHPGMNGGEHPFVRADITYFSTANGGGMFATSSISWLGSLSWNDYDNNVSKMTKNVLNQFIKDEPAPRV 6m5a A 1.85 BS01 CA A 1 N497 N499 N501 L503 D505 D532 N452 N454 N456 L458 D460 D483 A0A413AH52 IKNADVAYPSFKGSDDPMKTAANNTTYNPAVSYLQETFDNDVKNLAGIDTDHDFWIDKILTRTGAQPTGKGTNDKGAYSYEGSDGNNYLFTRGRAAYMYTHTPNQLGFVGDTAYWDQTSRSGFTVTVNADGSNQTLNEDASQRKQTPSYFTSLFQTGGKSLKIKEVKYITYNNVMVANLTVESTQDRDVTLTTASPFAAEGADGATELTGRVNVKNNLTTIYPRFSANNQDGSNWIVSGGKLTSTLSLKANEPQTVKIQLGLIANELPDSTKEYEARYTGDLKDAAASYKDSVTTYNKWWVDNAPYVDTPEDNIDKTVVYRWWLSRFNMLDANMPGNTFQYPTSIEGVLGYNNQIVLTSGMFMMDTKWFRNPEYSYGTWLSAGDTAKKSKAGYYYYHDNPSYTQYITRAGWDSYKVHGGPSTVAEELADQGAEDVQGLLASKSEPDNNDNQNNNDNSLIDWSWWSMADAVSFSEPGRSGQRMDRADGSANMWANANAAAQAYKAAGDTANAEKMQAIADKIQKEVTTELWDKSDNLLKHKWLNDGAFAKYKEINNYYPYSEGLMPTGNEDYNKALRLFEDSNEFPIFPFFTANQADKAALNFPGSNNFSIINAQPLLQVYSAGIRNYDAAKNGYITNEQFKKLLYWVAFAHYQGGDNNYPDQNEFWNEDNNNVGDVNGDGVINNLDKNLDAAQNGGKITYRSWIHHTQLGTTNWTMVEDVAGMVPREDNKIELNPIEIPGWNYFTVNNLRYHDQDVSIVWDKDGSHYGGPAGYSLYVGGKLAFTSDKLAHLIYDPAAGTVEVKDDSSAQVTVGAEAVKNVKAANQVTFNADQRVTDLFATNVLE 6m5a A 1.85 BS02 CA A 2 D724 N726 D728 V730 D735 D675 N677 D679 V681 D686 A0A413AH52 IKNADVAYPSFKGSDDPMKTAANNTTYNPAVSYLQETFDNDVKNLAGIDTDHDFWIDKILTRTGAQPTGKGTNDKGAYSYEGSDGNNYLFTRGRAAYMYTHTPNQLGFVGDTAYWDQTSRSGFTVTVNADGSNQTLNEDASQRKQTPSYFTSLFQTGGKSLKIKEVKYITYNNVMVANLTVESTQDRDVTLTTASPFAAEGADGATELTGRVNVKNNLTTIYPRFSANNQDGSNWIVSGGKLTSTLSLKANEPQTVKIQLGLIANELPDSTKEYEARYTGDLKDAAASYKDSVTTYNKWWVDNAPYVDTPEDNIDKTVVYRWWLSRFNMLDANMPGNTFQYPTSIEGVLGYNNQIVLTSGMFMMDTKWFRNPEYSYGTWLSAGDTAKKSKAGYYYYHDNPSYTQYITRAGWDSYKVHGGPSTVAEELADQGAEDVQGLLASKSEPDNNDNQNNNDNSLIDWSWWSMADAVSFSEPGRSGQRMDRADGSANMWANANAAAQAYKAAGDTANAEKMQAIADKIQKEVTTELWDKSDNLLKHKWLNDGAFAKYKEINNYYPYSEGLMPTGNEDYNKALRLFEDSNEFPIFPFFTANQADKAALNFPGSNNFSIINAQPLLQVYSAGIRNYDAAKNGYITNEQFKKLLYWVAFAHYQGGDNNYPDQNEFWNEDNNNVGDVNGDGVINNLDKNLDAAQNGGKITYRSWIHHTQLGTTNWTMVEDVAGMVPREDNKIELNPIEIPGWNYFTVNNLRYHDQDVSIVWDKDGSHYGGPAGYSLYVGGKLAFTSDKLAHLIYDPAAGTVEVKDDSSAQVTVGAEAVKNVKAANQVTFNADQRVTDLFATNVLE 6m5a A 1.85 BS03 CA A 3 D345 T346 D349 D352 D308 T309 D312 D315 A0A413AH52 IKNADVAYPSFKGSDDPMKTAANNTTYNPAVSYLQETFDNDVKNLAGIDTDHDFWIDKILTRTGAQPTGKGTNDKGAYSYEGSDGNNYLFTRGRAAYMYTHTPNQLGFVGDTAYWDQTSRSGFTVTVNADGSNQTLNEDASQRKQTPSYFTSLFQTGGKSLKIKEVKYITYNNVMVANLTVESTQDRDVTLTTASPFAAEGADGATELTGRVNVKNNLTTIYPRFSANNQDGSNWIVSGGKLTSTLSLKANEPQTVKIQLGLIANELPDSTKEYEARYTGDLKDAAASYKDSVTTYNKWWVDNAPYVDTPEDNIDKTVVYRWWLSRFNMLDANMPGNTFQYPTSIEGVLGYNNQIVLTSGMFMMDTKWFRNPEYSYGTWLSAGDTAKKSKAGYYYYHDNPSYTQYITRAGWDSYKVHGGPSTVAEELADQGAEDVQGLLASKSEPDNNDNQNNNDNSLIDWSWWSMADAVSFSEPGRSGQRMDRADGSANMWANANAAAQAYKAAGDTANAEKMQAIADKIQKEVTTELWDKSDNLLKHKWLNDGAFAKYKEINNYYPYSEGLMPTGNEDYNKALRLFEDSNEFPIFPFFTANQADKAALNFPGSNNFSIINAQPLLQVYSAGIRNYDAAKNGYITNEQFKKLLYWVAFAHYQGGDNNYPDQNEFWNEDNNNVGDVNGDGVINNLDKNLDAAQNGGKITYRSWIHHTQLGTTNWTMVEDVAGMVPREDNKIELNPIEIPGWNYFTVNNLRYHDQDVSIVWDKDGSHYGGPAGYSLYVGGKLAFTSDKLAHLIYDPAAGTVEVKDDSSAQVTVGAEAVKNVKAANQVTFNADQRVTDLFATNVLE 6oqr C 3.40 BS01 ATP C 1 Q172 G174 K175 T176 A177 F360 R365 Q433 Q435 Q171 G173 K174 T175 A176 F359 R364 Q432 Q434 7.1.2.2 A0A073FQ32 QLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW 6oqr B 3.40 BS01 ATP B 1 Q172 T173 G174 K175 T176 A177 F360 R365 Q433 Q435 Q172 T173 G174 K175 T176 A177 F360 R365 Q433 Q435 7.1.2.2 A0A073FQ32 MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQ 6oqr F 3.40 BS01 ATP C 1 R342 Y354 R341 Y353 7.1.2.2 A0A192CEZ8 TGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqr F 3.40 BS02 ADP F 1 G152 G154 K155 T156 V157 Y331 F404 A407 F410 G151 G153 K154 T155 V156 Y330 F403 A406 F409 7.1.2.2 A0A192CEZ8 TGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqr F 3.40 BS03 MG F 1 T156 E181 R182 E185 T155 E180 R181 E184 7.1.2.2 A0A192CEZ8 TGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqr E 3.40 BS01 ATP B 1 R342 D345 R343 D346 7.1.2.2 A0A192CEZ8 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqr E 3.40 BS02 ADP E 1 G152 G154 K155 T156 V157 Y331 F404 A407 F410 T411 G153 G155 K156 T157 V158 Y332 F405 A408 F411 T412 7.1.2.2 A0A192CEZ8 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqr D 3.40 BS01 ADP D 1 A151 G152 G154 K155 T156 V157 Y331 A407 F410 A152 G153 G155 K156 T157 V158 Y332 A408 F411 7.1.2.2 A0A192CEZ8 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqs A 3.60 BS01 ATP A 1 R171 Q172 T173 G174 K175 T176 A177 F360 Q433 Q435 R168 Q169 T170 G171 K172 T173 A174 F357 Q430 Q432 7.1.2.2 A0A073FQ32 NSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQ 6oqs F 3.60 BS01 ATP C 1 R342 D345 Y354 R341 D344 Y353 7.1.2.2 TGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqs F 3.60 BS02 ADP F 1 G152 V153 G154 K155 T156 V157 Y331 F404 A407 F410 T411 G151 V152 G153 K154 T155 V156 Y330 F403 A406 F409 T410 7.1.2.2 TGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqs E 3.60 BS02 ADP E 1 A151 G152 G154 K155 T156 V157 Y331 F404 A407 F410 A152 G153 G155 K156 T157 V158 Y332 F405 A408 F411 7.1.2.2 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqs D 3.60 BS01 ADP D 1 G152 G154 K155 T156 V157 Y331 A407 F410 G153 G155 K156 T157 V158 Y332 A408 F411 7.1.2.2 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqt F 3.30 BS02 MG F 1 T156 E181 R182 T155 E180 R181 7.1.2.2 TGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqu D 3.50 BS01 ADP D 1 G152 G154 K155 T156 V157 Y331 A407 F410 T411 G153 G155 K156 T157 V158 Y332 A408 F411 T412 7.1.2.2 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqv F 3.90 BS03 MG F 1 K155 T156 R182 K154 T155 R181 7.1.2.2 TGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqv E 3.90 BS01 ADP E 1 G152 G154 T156 V157 Y331 F404 A407 F410 G153 G155 T157 V158 Y332 F405 A408 F411 7.1.2.2 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6oqv D 3.90 BS01 ADP D 1 A151 G152 V153 G154 K155 T156 V157 Y331 A407 F410 A152 G153 V154 G155 K156 T157 V158 Y332 A408 F411 7.1.2.2 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6p2d A 1.79 BS01 FRU A 1 V13 D15 G40 G41 N42 N45 S97 L112 L254 D258 V11 D13 G38 G39 N40 N43 S95 L110 L252 D256 A0A0J9YU79 EKQILCVGLVVLDIINVVDKYPEEDTDRRCLSQRWQRGGNASNSCTVLSLLGARCAFMGSLAPGHVADFLVADFRQRGVDVSQVTWQSQGDTPCSCCIVNNSNGSRTIILYDTNLPDVSAKDFEKVDLTRFKWIHIEGRNASEQVKMLQRIEEHNAKQPLPQKVRVSVEIEKPREELFQLFSYGEVVFVSKDVAKHLGFQSAVEALRGLYSRVKKGATLVCAWAEEGADALGPDGQLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSKGNSMQEALRFGCQVAGKKCGLQGFDGIV 6p2d A 1.79 BS02 ADP A 1 R108 A224 A226 G229 P246 G257 F260 C282 A285 C289 R106 A222 A224 G227 P244 G255 F258 C280 A283 C287 A0A0J9YU79 EKQILCVGLVVLDIINVVDKYPEEDTDRRCLSQRWQRGGNASNSCTVLSLLGARCAFMGSLAPGHVADFLVADFRQRGVDVSQVTWQSQGDTPCSCCIVNNSNGSRTIILYDTNLPDVSAKDFEKVDLTRFKWIHIEGRNASEQVKMLQRIEEHNAKQPLPQKVRVSVEIEKPREELFQLFSYGEVVFVSKDVAKHLGFQSAVEALRGLYSRVKKGATLVCAWAEEGADALGPDGQLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSKGNSMQEALRFGCQVAGKKCGLQGFDGIV 6p4e A 1.35 BS01 GES A 1 Q20 G24 S25 C26 W27 S65 G66 G67 L68 M69 Q71 A140 N163 H164 Q19 G23 S24 C25 W26 S64 G65 G66 L67 M68 Q70 A139 N162 H163 3.4.22.- P36400 VPDAVDWREKGAVTPVKDQGACGSCWAFSAVGNIEGQWYLAGHELVSLSEQQLVSCDDMDNGCSGGLMLQAFDWLLQNTNGHLHTEDSYPYVSGNGYVPECSNSSELVVGAQIDGHVLIGSSEKAMAAWLAKNGPIAIALDASSFMSYKSGVLTACIGKQLNHGVLLVGYDMTGEVPYWVIKNSWGGDWGEQGYVRVVMGVNACLLSEYPVSAHVR 6p4w A 2.96 BS01 MG A 1 K96 D174 K97 D175 Q970I2 GSVYLRYFKGLILSDAYAPGLKWSDELKAYSALAFKYRDVRKYFLEKEIEVEENVIDSLPFPLIKDKIELRDYQAEAVKAWLKEKRGIIVLPTGAGKTQVALKIVSIMKVATLIVVPTIDLITQWKERINKYLDFDPGIIGGGEDSLKGITVITYDSAYTRAEELGNKFPLLIFDEVHHLPSEGYSIMAQLFASPYRLGLTATPERDDGKHELYPILVGPIVYRKSVEELAGKYIAKYKIKKLYVSLTNEEKKRYDGLRKKLKDFLSSRGLKLQNLDDFHRLVKLAAKDKEAREALLAWHESLNIAVNSQSKIEKLREILQEYKNEKIIVFTRDTQMAYRISKTFLIPVVTYKTDKDEREEILQKFRDGEYRVIVASTVFDEGVDVPDATLAIVMGGYGTKRQFLQRLGRILRKKDKEALLIEIVTKGTADYRLS 6p60 A 2.50 BS01 III E 1 Y34 I38 W48 Y51 D100 G101 V102 D110 Y33 I37 W47 Y50 D99 G100 V101 D109 VQLQESGPGLVKPSETLSLTCAVTGGSISDAYYWSWIRQFPGKRLEWIGYIYGSTGGTRYNPPLKNRVSISIDTSKNQFSLKLRSVTAADTAVYYCVRDGVATIETTGDHWGQGVLVTVSSASTKGPSVFPLAPSSRSTSESTAALGCLVKDYFPEPVTVSWNSGSLTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYVCNVNHKPSNTKVDKRVEI 6p60 B 2.50 BS01 III E 1 Y33 Y37 L47 Y50 E51 Q90 Y92 H99 F101 Y32 Y36 L46 Y49 E50 Q89 Y91 H98 F100 FVLAQPPSVSGAPGQRVTLSCTGSNSNIGVNYVQWYQQLPGTAPKLLIYENNKRPSGVSDRFSGSQSGTSASLTITGLQSEDEADYYCQCYDISLGAHVFGSGTELTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVEVAWKADGSAVNAGVETTKPSKQSNNKYAASSYLSLTSDQWKSHKSYSCQVTHEGSTVEKTVAP 6p60 C 2.50 BS01 III F 1 Y34 S36 W48 Y51 D100 G101 V102 A103 G109 D110 Y33 S35 W47 Y50 D99 G100 V101 A102 G108 D109 VQLQESGPGLVKPSETLSLTCAVTGGSISDAYYWSWIRQFPGKRLEWIGYIYGSTGGTRYNPPLKNRVSISIDTSKNQFSLKLRSVTAADTAVYYCVRDGVATIETTGDHWGQGVLVTVSSASTKGPSVFPLAPSSRSTSESTAALGCLVKDYFPEPVTVSWNSGSLTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYVCNVNHKPSNTKVDKRVEI 6p60 D 2.50 BS01 III F 1 N32 Y33 Q35 Y37 L47 Y50 E51 Y92 H99 N31 Y32 Q34 Y36 L46 Y49 E50 Y91 H98 FVLAQPPSVSGAPGQRVTLSCTGSNSNIGVNYVQWYQQLPGTAPKLLIYENNKRPSGVSDRFSGSQSGTSASLTITGLQSEDEADYYCQCYDISLGAHVFGSGTELTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVEVAWKADGSAVNAGVETTKPSKQSNNKYAASSYLSLTSDQWKSHKSYSCQVTHEGSTVEKTVAP 6p60 G 2.50 BS01 III I 1 Y34 I38 Y51 D100 G101 V102 T107 G109 D110 Y33 I37 Y50 D99 G100 V101 T106 G108 D109 VQLQESGPGLVKPSETLSLTCAVTGGSISDAYYWSWIRQFPGKRLEWIGYIYGSTGGTRYNPPLKNRVSISIDTSKNQFSLKLRSVTAADTAVYYCVRDGVATIETTGDHWGQGVLVTVSSASTKGPSVFPLAPESTAALGCLVKDYFPEPVTVSWNSGSLTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYVCNVNHKPSNTKVDKRVEI 6p60 J 2.50 BS01 III L 1 Y34 I38 Y51 D100 G101 V102 A103 T107 G109 D110 Y33 I37 Y50 D99 G100 V101 A102 T106 G108 D109 VQLQESGPGLVKPSETLSLTCAVTGGSISDAYYWSWIRQFPGKRLEWIGYIYGSTGGTRYNPPLKNRVSISIDTSKNQFSLKLRSVTAADTAVYYCVRDGVATIETTGDHWGQGVLVTVSSASTKGPSVFPLAPESTAALGCLVKDYFPEPVTVSWNSGSLTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYVCNVNHKPSNTKVDKRVEI 6p60 K 2.50 BS01 III L 1 N32 Y33 Q35 Y37 Y50 E51 Q90 Y92 H99 F101 N32 Y33 Q35 Y37 Y50 E51 Q90 Y92 H99 F101 QFVLAQPPSVSGAPGQRVTLSCTGSNSNIGVNYVQWYQQLPGTAPKLLIYENNKRPSGVSDRFSGSQSGTSASLTITGLQSEDEADYYCQCYDISLGAHVFGSGTELTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVEVAWKADGSAVNAGVETTKPSKQSNNKYAASSYLSLTSDQWKSHKSYSCQVTHEGSTVEKTVAP 6p63 A 2.40 BS01 AMP A 1 G155 H156 Q277 S278 N301 M302 R306 A390 H443 E445 N446 D463 E467 G154 H155 Q276 S277 N300 M301 R305 A389 H442 E444 N445 D462 E466 Q9L069 SLADAVAHLTPERWEEANRLLVRKALAEFTHERLLTPEREPDDGGGQTYVVRSDDGQTAYRFTATVRALDHWQVDAASVTRHRDGAELPLAALDFFIELKQTLGLSDEILPVYLEEISSTLSGTCYKLTKPQLSSAELARSGDFQAVETGMTEGHPCFVANNGRLGFGIHEYLSYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFVRDELGAATVDRFHGVLRGRGLDPADYLLIPVHPWQWWNKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRTFFNASHPGKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIEGDPVLKETGLSIIRERAAVGYRHLEYEQATDRYSPYRKMLAALWRESPVPSIREGETLATMASLVHQDHEGASFAGALIERSGLTPTEWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRRAVYKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEGIVTEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQMVDLADPSGALQLVGTLKNPLAGR 6p63 A 2.40 BS02 MG A 1 E445 N446 D463 E444 N445 D462 Q9L069 SLADAVAHLTPERWEEANRLLVRKALAEFTHERLLTPEREPDDGGGQTYVVRSDDGQTAYRFTATVRALDHWQVDAASVTRHRDGAELPLAALDFFIELKQTLGLSDEILPVYLEEISSTLSGTCYKLTKPQLSSAELARSGDFQAVETGMTEGHPCFVANNGRLGFGIHEYLSYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFVRDELGAATVDRFHGVLRGRGLDPADYLLIPVHPWQWWNKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRTFFNASHPGKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIEGDPVLKETGLSIIRERAAVGYRHLEYEQATDRYSPYRKMLAALWRESPVPSIREGETLATMASLVHQDHEGASFAGALIERSGLTPTEWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRRAVYKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEGIVTEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQMVDLADPSGALQLVGTLKNPLAGR 6p63 C 2.40 BS01 N2P C 1 R280 M305 R306 G307 E467 R280 M305 R306 G307 E467 Q9L069 MSLADAVAHLTPERWEEANRLLVRKALAEFTHERLLTPEREPDDGGGQTYVVRSDDGQTAYRFTATVRALDHWQVDAASVTRHRDGAELPLAALDFFIELKQTLGLSDEILPVYLEEISSTLSGTCYKLTKPQLSSAELARSGDFQAVETGMTEGHPCFVANNGRLGFGIHEYLSYAPETASPVRLVWLAAHRSRAAFTAGVGIEYESFVRDELGAATVDRFHGVLRGRGLDPADYLLIPVHPWQWWNKLTVTFAAEVARGHLVCLGEGDDEYLAQQSIRTFFNASHPGKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLARLIEGDPVLKETGLSIIRERAAVGYRHLEYEQATDRYSPYRKMLAALWRESPVPSIREGETLATMASLVHQDHEGASFAGALIERSGLTPTEWLRHYLRAYYVPLLHSFYAYDLVYMPHGENVILVLADGVVRRAVYKDIAEEIAVMDPDAVLPPEVSRIAVDVPDDKKLLSIFTDVFDCFFRFLAANLAEEGIVTEDAFWRTVAEVTREYQESVPELADKFERYDMFAPEFALSCLNRLQLRDNRQMVDLADPSGALQLVGTLKNPLAGR 6p64 A 3.05 BS01 III C 1 Y7 Y9 M45 Y59 E63 K66 V67 A69 H70 T73 V76 D77 T80 L81 Y99 H114 Y116 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 Y7 Y9 M45 Y59 E63 K66 V67 A69 H70 T73 V76 D77 T80 L81 Y99 H114 Y116 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 U5YJP1 GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE 6p64 F 3.05 BS01 III H 1 Y7 Y9 M45 Y59 E63 K66 V67 A69 H70 T73 V76 D77 T80 L81 Y84 R97 Y99 H114 Y116 Y123 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 Y7 Y9 M45 Y59 E63 K66 V67 A69 H70 T73 V76 D77 T80 L81 Y84 R97 Y99 H114 Y116 Y123 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 U5YJP1 GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTTLRCWALSFYPAEITLTWRDGEDQTTELVETRPAGDGTFQKWAAVEQRYTCHVQHEGLPKPLTLRW 6pqv F 3.30 BS02 ADP F 1 G152 G154 K155 T156 V157 Y331 F404 A407 T411 G151 G153 K154 T155 V156 Y330 F403 A406 T410 7.1.2.2 TGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6qba A 1.80 BS01 2T1 A 1 L35 F36 L37 A55 A57 M73 V74 M88 Y90 F96 Q98 H104 R121 Y133 F135 L35 F36 L37 A55 A57 M73 V74 M88 Y90 F96 Q98 H104 R121 Y133 F135 P02753 ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDG 6qba A 1.80 BS02 ZN A 1 H170 D175 H170 D175 P02753 ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDG 6ra9 A 2.70 BS01 GPE A 1 A373 E374 A369 E370 Q71V39 KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKS 6ra9 A 2.70 BS02 GPE A 2 T242 E301 L303 T238 E297 L299 Q71V39 KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKS 6ra9 A 2.70 BS03 GDP A 1 D17 S18 G19 K20 S21 T22 S53 N153 K154 D156 S157 S194 G195 W196 D13 S14 G15 K16 S17 T18 S49 N149 K150 D152 S153 S190 G191 W192 Q71V39 KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKS 6rkt A 1.75 BS02 K7H A 1 D102 S103 Y106 D156 C158 I201 G229 L231 A232 M260 G261 D93 S94 Y97 D140 C142 I184 G212 L214 A215 M243 G244 2.4.2.29 P28720 DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLTKQSEEGVTFKSSRHMLSPERSIEIQHLLGSDIVMAFDECTYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 6rll A 2.22 BS01 K8H A 1 P314 Y324 F327 G365 G367 E392 K393 S418 D419 M420 E435 L436 L437 E444 C449 P302 Y312 F315 G353 G355 E380 K381 S406 D407 M408 E423 L424 L425 E432 C437 2.1.1.320 O14744 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 6rm2 A 2.50 BS01 ATP A 1 S14 T15 G16 K17 G18 G42 H43 T44 R269 N294 F295 N297 G330 P331 S14 T15 G16 K17 G18 G42 H43 T44 R269 N294 F295 N297 G330 P331 G3FFN6 MENVDLVIDLQFGSTGKGLIAGYLAEKNGYDTVINANMPNAGHTYINAEGRKWMHKVLPNGIVSPNLKRVMLGAGSVFSINRLMEEIEMSKDLLHDKVAILIHPMATVLDEEAHKKAEVGIATSIGSTGQGSMAAMVEKLQRDPTNNTIVARDVAQYDGRIAQYVCTVEEWDMALMASERILAEGAQGFSLSLNQEFYPYCTSRDCTPARFLADMGIPLPMLNKVIGTARCHPIRVGGTSGGHYPDQEELTWEQLGQVPELTTVTKKVRRVFSFSFIQMQKAMWTCQPDEVFLNFCNYLSPMGWQDIVHQIEVAAQSRYCDAEVKYLGFGPTFNDVELREDVM 6rm2 A 2.50 BS02 MG A 1 S14 A41 G42 H43 S14 A41 G42 H43 G3FFN6 MENVDLVIDLQFGSTGKGLIAGYLAEKNGYDTVINANMPNAGHTYINAEGRKWMHKVLPNGIVSPNLKRVMLGAGSVFSINRLMEEIEMSKDLLHDKVAILIHPMATVLDEEAHKKAEVGIATSIGSTGQGSMAAMVEKLQRDPTNNTIVARDVAQYDGRIAQYVCTVEEWDMALMASERILAEGAQGFSLSLNQEFYPYCTSRDCTPARFLADMGIPLPMLNKVIGTARCHPIRVGGTSGGHYPDQEELTWEQLGQVPELTTVTKKVRRVFSFSFIQMQKAMWTCQPDEVFLNFCNYLSPMGWQDIVHQIEVAAQSRYCDAEVKYLGFGPTFNDVELREDVM 6rm2 B 2.50 BS03 IMP B 1 F12 N40 A41 I125 S127 T128 Q187 L191 C201 T202 V236 S240 F12 N40 A41 I125 S127 T128 Q187 L191 C201 T202 V236 S240 G3FFN6 MENVDLVIDLQFGSTGKGLIAGYLAEKNGYDTVINANMPNAGHTYINAEGRKWMHKVLPNGIVSPNLKRVMLGAGSVFSINRLMEEIEMSKDLLHDKVAILIHPMATVLDEEAHKKAEVGIATSIGSTGQGSMAAMVEKLQRDPTNNTIVARDVAQYDGRIAQYVCTVEEWDMALMASERILAEGAQGFSLSLNQEFYPYCTSRDCTPARFLADMGIPLPMLNKVIGTARCHPIRVGGTSGGHYPDQEELTWEQLGQVPELTTVTKKVRRVFSFSFIQMQKAMWTCQPDEVFLNFCNYLSPMGWQDIVHQIEVAAQSRYCDAEVKYLGFGPTFNDVELREDVM 6rmx A 1.60 BS02 5DU A 1 N62 H64 Q92 H94 H96 H119 V121 F131 L198 T199 V200 P202 N59 H61 Q89 H91 H93 H116 V118 F127 L194 T195 V196 P198 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTVPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 6rmy A 1.50 BS02 V14 A 1 W5 H64 A65 N67 H94 H96 H119 V121 F131 L141 V143 L198 T199 V200 W209 W3 H62 A63 N65 H92 H94 H117 V119 F128 L138 V140 L195 T196 V197 W206 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTVPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 6rof A 1.50 BS02 V90 A 1 N62 H64 N67 Q92 H94 H96 H119 F131 L198 T199 V200 N60 H62 N65 Q90 H92 H94 H117 F128 L195 T196 V197 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTVPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 6s03 A 1.38 BS02 KPW A 1 L91 H94 H96 H119 V121 V130 V134 V142 L197 T198 T199 P201 W208 L88 H91 H93 H116 V118 V127 V131 V139 L194 T195 T196 P198 W205 4.2.1.1 P00918 32452709 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVVKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 6sp1 A 2.57 BS01 LQ8 A 1 Y334 G364 L365 R380 N414 R415 G462 G509 A556 Y572 F577 S602 G603 V604 Y10 G40 L41 R56 N90 R91 G138 G185 A232 Y248 F253 S278 G279 V280 Q14145 32435379 GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 6sp4 A 2.59 BS01 LQK A 1 Y334 S363 G364 L365 R380 N414 R415 I416 A556 Y572 F577 S602 G603 Y9 S38 G39 L40 R55 N89 R90 I91 A231 Y247 F252 S277 G278 Q14145 32435379 RLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 6sp4 B 2.59 BS01 LQK B 1 S363 G364 L365 R380 N414 R415 G509 A556 L557 Y572 F577 S602 G603 S39 G40 L41 R56 N90 R91 G185 A232 L233 Y248 F253 S278 G279 Q14145 32435379 GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 6sp4 D 2.59 BS01 LQK D 1 Y334 S363 G364 L365 R380 N414 R415 G509 A556 S602 G603 Y9 S38 G39 L40 R55 N89 R90 G184 A231 S277 G278 Q14145 32435379 RLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 6sp4 E 2.59 BS01 LQK E 1 Y334 G364 L365 N414 R415 A556 Y572 F577 S602 G603 V604 Y9 G39 L40 N89 R90 A231 Y247 F252 S277 G278 V279 Q14145 32435379 RLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 6sp4 F 2.59 BS01 LQK F 1 Y334 S363 G364 L365 R380 N414 R415 I416 G509 A556 Y572 F577 S602 G603 V604 Y11 S40 G41 L42 R57 N91 R92 I93 G186 A233 Y249 F254 S279 G280 V281 Q14145 32435379 VGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 6sw1 A 1.80 BS01 FAD A 1 G12 G14 G16 V34 E35 Q36 N44 R45 A46 A160 D161 G162 Y166 I272 P273 G291 D292 G302 G304 G9 G11 G13 V31 E32 Q33 N41 R42 A43 A157 D158 G159 Y163 I269 P270 G288 D289 G299 G301 Q9HWJ1 NHIDVLINGCGIGGAMLAYLLGRQGHRVVVVEQARREYARNRADLLKPAGIRVVEAAGLLAEVTRRGGRVRHELEVYHDGELLRYFNYSSVDARGYFILMPGESLRRLVLEKIDGEATVEMLFETRIEAVQRDERHAIDQVRLNDGRVLRPRVVVGADGIASYVRRRLLDIDVERRPYPSPMLVGTFALAPCVAERNRLYVDSQGGLAYFYPIGFDRARLVVSFPREEARELMADTRGESLRRRLQRFVGDESAEAIAAVTGTSRFKGIPIGYLNLDRYWADNVAMLGDAIHNVHPITGQGMNLAIEDASALADALDLALRDACALEDALAGYQAERFPVNQAIVSYGHALATSLEDRQRFAGVFDT 6sw2 A 1.70 BS01 FAD A 1 N11 G12 G14 I15 G16 V34 E35 Q36 R41 N44 G45 A46 A160 D161 G162 Y166 G271 I272 P273 G291 D292 P299 G302 Q303 G304 A308 N8 G9 G11 I12 G13 V31 E32 Q33 R38 N41 G42 A43 A157 D158 G159 Y163 G268 I269 P270 G288 D289 P296 G299 Q300 G301 A305 Q9HWJ1 NHIDVLINGCGIGGAMLAYLLGRQGHRVVVVEQARRERAINGADLLKPAGIRVVEAAGLLAEVTRRGGRVRHELEVYHDGELLRYFNYSSVDARGYFILMPCESLRRLVLEKIDGEATVEMLFETRIEAVQRDERHAIDQVRLNDGRVLRPRVVVGADGIASYVRRRLLDIDVERRPYPSPMLVGTFALAPCVAERNRLYVDSQGGLAYFYPIGFDRARLVVSFPREEARELMADTRGESLRRRLQRFVGDESAEAIAAVTGTSRFKGIPIGYLNLDRYWADNVAMLGDAIHNVHPITGQGMNLAIEDASALADALDLALRDACALEDALAGYQAERFPVNQAIVSYGHALATSLEDRQRFAGVFDT 6sw2 A 1.70 BS02 61M A 1 A46 D47 L48 Y212 Y214 P299 I300 G302 A43 D44 L45 Y209 Y211 P296 I297 G299 Q9HWJ1 NHIDVLINGCGIGGAMLAYLLGRQGHRVVVVEQARRERAINGADLLKPAGIRVVEAAGLLAEVTRRGGRVRHELEVYHDGELLRYFNYSSVDARGYFILMPCESLRRLVLEKIDGEATVEMLFETRIEAVQRDERHAIDQVRLNDGRVLRPRVVVGADGIASYVRRRLLDIDVERRPYPSPMLVGTFALAPCVAERNRLYVDSQGGLAYFYPIGFDRARLVVSFPREEARELMADTRGESLRRRLQRFVGDESAEAIAAVTGTSRFKGIPIGYLNLDRYWADNVAMLGDAIHNVHPITGQGMNLAIEDASALADALDLALRDACALEDALAGYQAERFPVNQAIVSYGHALATSLEDRQRFAGVFDT 6tbu A 3.16 BS01 Y01 A 1 L39 L44 P45 D46 F47 L445 C480 L483 G484 F499 L504 L34 L39 P40 D41 F42 L253 C288 L291 G292 F307 L312 Q9VNJ5 SERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWESSPRKEYSHFVVQRINATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEKRLNIVFNVLNFLTDFSFIVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKELPNCFIENLIDYMKRRCIPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLEL 6tbu A 3.16 BS02 Y01 A 2 L445 V448 C480 L483 L253 V256 C288 L291 Q9VNJ5 SERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWESSPRKEYSHFVVQRINATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEKRLNIVFNVLNFLTDFSFIVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKELPNCFIENLIDYMKRRCIPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLEL 6tbu A 3.16 BS03 Y01 A 3 W11 V15 R19 L22 V23 S26 I27 Y30 W6 V10 R14 L17 V18 S21 I22 Y25 Q9VNJ5 SERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWESSPRKEYSHFVVQRINATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEKRLNIVFNVLNFLTDFSFIVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKELPNCFIENLIDYMKRRCIPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLEL 6tbu A 3.16 BS04 Y01 A 4 C661 S665 Y669 W673 F677 F1100 F1104 C425 S429 Y433 W437 F441 F820 F824 Q9VNJ5 SERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWESSPRKEYSHFVVQRINATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEKRLNIVFNVLNFLTDFSFIVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKELPNCFIENLIDYMKRRCIPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLEL 6tbu A 3.16 BS05 Y01 A 5 A1066 T1067 G1070 L1071 G1074 I1075 M1077 A1078 V1092 I1096 A786 T787 G790 L791 G794 I795 M797 A798 V812 I816 Q9VNJ5 SERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWESSPRKEYSHFVVQRINATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEKRLNIVFNVLNFLTDFSFIVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKELPNCFIENLIDYMKRRCIPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLEL 6tbu A 3.16 BS06 Y01 A 6 F677 L680 N1001 V1005 L1009 M1077 I1085 V1089 V1092 V1093 I1096 V1097 F1100 Y1101 F441 L444 N721 V725 L729 M797 I805 V809 V812 V813 I816 V817 F820 Y821 Q9VNJ5 SERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWESSPRKEYSHFVVQRINATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEKRLNIVFNVLNFLTDFSFIVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKELPNCFIENLIDYMKRRCIPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLEL 6tbu A 3.16 BS07 Y01 A 7 L680 S683 S684 I687 N1001 V1005 L1008 L1009 L444 S447 S448 I451 N721 V725 L728 L729 Q9VNJ5 SERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWESSPRKEYSHFVVQRINATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEKRLNIVFNVLNFLTDFSFIVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKELPNCFIENLIDYMKRRCIPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLEL 6tbu A 3.16 BS08 Y01 A 8 A679 A682 S683 V686 I687 Y691 I1007 L1008 A443 A446 S447 V450 I451 Y455 I727 L728 Q9VNJ5 SERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWESSPRKEYSHFVVQRINATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEKRLNIVFNVLNFLTDFSFIVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKELPNCFIENLIDYMKRRCIPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLEL 6tbu A 3.16 BS09 Y01 A 9 L579 A582 G583 Y586 A587 Y589 S590 L969 L361 A364 G365 Y368 A369 Y371 S372 L689 Q9VNJ5 SERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWESSPRKEYSHFVVQRINATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEKRLNIVFNVLNFLTDFSFIVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPYNFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKELPNCFIENLIDYMKRRCIPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLEL 6te1 A 3.11 BS01 N4K A 1 I356 Q358 E379 W531 H532 N535 L536 A539 W552 D556 H564 W695 I186 Q188 E209 W361 H362 N365 L366 A369 W382 D386 H394 W525 1.-.-.- O60341 32435381 PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTL 6te1 A 3.11 BS02 N4K A 2 M332 V333 T335 F538 A539 D555 H564 K661 W695 L697 P808 A809 T810 M162 V163 T165 F368 A369 D385 H394 K491 W525 L527 P638 A639 T640 1.-.-.- O60341 32435381 PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTL 6te1 A 3.11 BS03 FAD A 1 G285 G287 V288 S289 E308 A309 R310 G314 G315 R316 V317 L329 G330 A331 V333 T588 A589 V590 T624 L625 P626 V637 W756 S760 Y761 G800 E801 A809 T810 V811 A814 G115 G117 V118 S119 E138 A139 R140 G144 G145 R146 V147 L159 G160 A161 V163 T418 A419 V420 T454 L455 P456 V467 W586 S590 Y591 G630 E631 A639 T640 V641 A644 1.-.-.- O60341 32435381 PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTL 6tgh A 2.12 BS02 DSN C 1 E57 Y65 E51 Y59 2.1.2.1 Q5MCK9 DYKAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKTAEGYPGKRYYGGTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAGGHLTHGAPVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGLILTDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALENHDKPEVLERIRGDVKVLTDAFPLY 6tgh C 2.12 BS02 DSN C 1 S35 H126 H204 R363 S29 H120 H198 R357 2.1.2.1 Q5MCK9 DYKAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKTAEGYPGKRYYGGTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAGGHLTHGAPVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGLILTDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALENHDKPEVLERIRGDVKVLTDAFPLY 6tgh C 2.12 BS03 PLP C 1 S97 G98 S99 H126 H129 D201 A203 H204 T227 H229 K230 S91 G92 S93 H120 H123 D195 A197 H198 T221 H223 K224 2.1.2.1 Q5MCK9 DYKAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKTAEGYPGKRYYGGTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAGGHLTHGAPVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGLILTDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALENHDKPEVLERIRGDVKVLTDAFPLY 6tgh D 2.12 BS01 EVM B 1 Y65 G261 G262 Y59 G255 G256 2.1.2.1 Q5MCK9 DYKAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKTAEGYPGKRYYGGTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAGGHLTHGAPVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGLILTDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALENHDKPEVLERIRGDVKVLTDAFPLY 6tgh D 2.12 BS02 DSN D 1 S35 H126 H204 K230 R363 S29 H120 H198 K224 R357 2.1.2.1 Q5MCK9 DYKAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKTAEGYPGKRYYGGTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAGGHLTHGAPVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGLILTDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALENHDKPEVLERIRGDVKVLTDAFPLY 6tqh A 3.40 BS01 NAD A 1 D487 F489 D519 G545 G546 S547 D550 T597 T598 T601 S603 T606 F608 V610 K619 L638 M642 L646 H657 F714 H723 H727 H737 D487 F489 D519 G545 G546 S547 D550 T597 T598 T601 S603 T606 F608 V610 K619 L638 M642 L646 H657 F714 H723 H727 H737 1.1.1.1,1.2.1.10 P0A9Q7 32188856 MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQGKELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAHEKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTARILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQILLDTYYGRDYVE 6tqh A 3.40 BS02 NAD A 2 I110 V111 T113 T114 N115 P138 H139 S178 M182 T193 G194 G195 M198 A201 V212 G213 A214 C246 E335 H367 T418 L419 I110 V111 T113 T114 N115 P138 H139 S178 M182 T193 G194 G195 M198 A201 V212 G213 A214 C246 E335 H367 T418 L419 1.1.1.1,1.2.1.10 P0A9Q7 32188856 MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQGKELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAHEKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTARILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQILLDTYYGRDYVE 6tqh A 3.40 BS03 FE A 1 D653 H657 H723 H737 N741 D653 H657 H723 H737 N741 1.1.1.1,1.2.1.10 P0A9Q7 32188856 MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQGKELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAHEKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTARILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQILLDTYYGRDYVE 6tqh B 3.40 BS01 NAD B 1 I110 V111 P112 T113 T114 N115 P138 H139 M182 T193 G194 G197 M198 A201 V212 G213 A214 C246 E335 L337 H367 T418 L419 I110 V111 P112 T113 T114 N115 P138 H139 M182 T193 G194 G197 M198 A201 V212 G213 A214 C246 E335 L337 H367 T418 L419 1.1.1.1,1.2.1.10 P0A9Q7 32188856 MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQGKELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAHEKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTARILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQILLDTYYGRDYVE 6tqm B 3.80 BS02 TXE B 1 D487 L490 G545 G546 S547 D550 K553 T597 S603 F608 A609 M642 L646 H727 D487 L490 G545 G546 S547 D550 K553 T597 S603 F608 A609 M642 L646 H727 1.1.1.1,1.2.1.10 P0A9Q7 32188856 MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQGKELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAHEKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTARILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQILLDTYYGRDYVE 6tqp A 1.85 BS01 III B 1 I49 K52 Y53 N56 L57 Y59 I60 L63 L64 H76 D79 Q80 E83 S84 R90 S92 V93 L95 A96 I97 F138 I141 K142 I47 K50 Y51 N54 L55 Y57 I58 L61 L62 H74 D77 Q78 E81 S82 R88 S90 V91 L93 A94 I95 F136 I139 K140 Q9DHU6 32412687 NSCNFNNSIKNVIVFYINEKALIEEKKMLSCYENKLLNLIKEDCENIMLKYKPNLSYICSLLKVDDTSEENIKHIKDQIIESLENDNRPSVKLAIISLISMIVEMNGYKGKNIPMSFLIEDIALKISENSEDLINFINIKNK 6tqq A 3.00 BS01 III B 1 I49 K52 Y53 N56 L57 Y59 I60 L63 L64 H76 Q80 S84 N87 R90 S92 V93 L95 A96 I97 F138 I44 K47 Y48 N51 L52 Y54 I55 L58 L59 H71 Q75 S79 N82 R84 S86 V87 L89 A90 I91 F132 Q9DHU6 32412687 NFNNSIKNVIVFYINEKALIEEKKMLSCYENKLLNLIKEDCENIMLKYKPNLSYICSLLKVDDTSEENIKHIKDQIIESLENNRPSVKLAIISLISMIVEMNGYKGKNIPMSFLIEDIALKISENSEDLINFINIKN 6trr A 2.12 BS01 III B 1 I49 Y53 N56 L57 Y59 I60 L63 L64 Q80 I81 S84 D88 R90 S92 V93 A96 I97 L100 F138 I141 K142 I45 Y49 N52 L53 Y55 I56 L59 L60 Q76 I77 S80 D84 R86 S88 V89 A92 I93 L96 F134 I137 K138 Q9DHU6 32412687 CNFNNSIKNVIVFYINEKALIEEKKMLSCYENKLLNLIKEDCENIMLKYKPNLSYICSLLKVDDTSEENIKHIKDQIIESLENDNRPSVKLAIISLISMIVEMNGYKGKNIPMSFLIEDIALKISENSEDLINFINIKNK 6tww A 1.38 BS01 MG A 1 H256 H293 H226 H263 ALSEQLAELEKRSGGRLGVAVLDTATGRRFGYRGDERFPMCSTFKALLAAAVLARVDQGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITYSDNTAANLLLEALGGPAALTAFLRSIGDNVTRLDRWEPELNTAAPGDPRDTTTPAAMAATLRTLLLGDVLSPASRQQLVDWLIANKTGDKRLRAGLPADDRVGDKTGTGEHGTTNDIAVVWPPNHAPIFIAVYLTESQVDADARDAVIAEVARLIVAAWHHHHHH 6ty6 A 1.80 BS01 6NT A 1 V48 L225 D229 V250 P252 I259 V286 W290 V22 L198 D202 V222 P224 I230 V257 W261 AALSEQLAELEKRSGGRLGVAVLDTATGRRFGYRGDERFPMCSTFKALLAAAVLARVDQGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITYSDNTAANLLLEALGGPAALTAFLRSIGDNVTRLDRWEPELNTAAPGDPRDTTTPAAMAATLRTLLLGDVLSPASRQQLVDWLIANKTGDKRLRAGLPADDRVGDKTGTGEHGTTNDIAVVWPPNRAPIFLAVYLTESQVDADARDAVIAEVARLVVAAWLHHH 6ty6 B 1.80 BS01 6NT B 1 L225 D229 V250 I259 L261 V286 V287 W290 L198 D202 V222 I230 L232 V257 V258 W261 AALSEQLAELEKRSGGRLGVAVLDTATGRRFGYRGDERFPMCSTFKALLAAAVLARVDQGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITYSDNTAANLLLEALGGPAALTAFLRSIGDNVTRLDRWEPELNTAAPGDPRDTTTPAAMAATLRTLLLGDVLSPASRQQLVDWLIANKTGDKRLRAGLPADDRVGDKTGTGEHGTTNDIAVVWPPNRAPIFLAVYLTESQVDADARDAVIAEVARLVVAAWLHHHH 6ty6 C 1.80 BS01 6NT C 1 V48 D229 V250 I259 L261 V286 V287 W290 V22 D202 V222 I230 L232 V257 V258 W261 AALSEQLAELEKRSGGRLGVAVLDTATGRRFGYRGDERFPMCSTFKALLAAAVLARVDQGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITYSDNTAANLLLEALGGPAALTAFLRSIGDNVTRLDRWEPELNTAAPGDPRDTTTPAAMAATLRTLLLGDVLSPASRQQLVDWLIANKTGDKRLRAGLPADDRVGDKTGTGEHGTTNDIAVVWPPNRAPIFLAVYLTESQVDADARDAVIAEVARLVVAAWLHHH 6uuo A 3.29 BS01 QH1 A 1 A481 L514 T529 W531 C532 F583 D594 F595 A28 L60 T75 W77 C78 F129 D140 F141 2.7.11.1 P15056 WEIPDGQITVGQRIFGTVYKGKWHGDVAVKMLNVTPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNNIFLHEDNTVKIGDFFEQLSGSILWMAPEVIRMQDSNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELARELS 6uuo B 3.29 BS01 QH1 B 1 A481 K483 L505 L514 I527 T529 W531 C532 S536 H539 N580 F583 G593 D594 F595 G596 A32 K34 L54 L63 I76 T78 W80 C81 S85 H88 N129 F132 G142 D143 F144 G145 2.7.11.1 P15056 DDWEIPDGQITVGQRIGSFGTVYKGKWHGDVAVKMLNVPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNNIFLHEDNTVKIGDFGGSILWMAPEVIRMQDSNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELAREL 6uwf A 3.08 BS01 ASP A 1 R276 S278 T314 G354 V355 P356 G357 A358 G359 D394 R397 T398 N401 R275 S277 T313 G353 V354 P355 G356 A357 G358 D393 R396 T397 N400 GLYRKYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE 6uwf A 3.08 BS02 6OU A 1 L90 P128 L130 I133 L134 I309 L347 I350 G351 M362 L89 P127 L129 I132 L133 I308 L346 I349 G350 M361 GLYRKYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE 6uwf A 3.08 BS03 6OU A 2 L3 Y4 Y7 L53 K196 I197 G200 Y204 I207 L2 Y3 Y6 L52 K195 I196 G199 Y203 I206 GLYRKYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE 6v1x A 3.50 BS01 QNP A 1 W75 S179 R197 K200 S203 V204 Y290 W26 S127 R145 K148 S151 V152 Y238 Q39128 HIISPFNPRYRAWEMWLVLLVIYSAWICPFQFAFITYKKDAIFIIDNIVNGFFAIDIILTFFVAYLDSHSYLLVDSPKKIAIRYLSTWFAFDVCSTAPFQPLSLLFNYELGFRILSMLRLWRLRRVSSLFARLEKDIRFNYFWIRCTKLISVTLFAIHCAGCFNYLIADRYPNPRKTWIGAVYPNFKEASLWNRYVTALYWSITTLTTTGYGDFHAENPREMLFDIFFMMFNLGLTAYLIGNMTNLVVHWTSRTRTFRDSVRAASEFASRNQLPHDIQDQMLSHICLKFKTEGLKQQETLNNLPKAIRSSIANYLFFPIVHNIYLFQGVSRNFLFQLVSDIDAEYFPPKEDIILQNEAPTDLYILVSGAVDFTVYVDGHDQFQGKAVIGETFGEVGVLYYRPQPFTVRTTELSQILRISRTSLMSAMHAHADDGRVIMNNLFMKLR 6v1x A 3.50 BS02 QNJ A 1 S179 A208 F283 S127 A156 F231 Q39128 HIISPFNPRYRAWEMWLVLLVIYSAWICPFQFAFITYKKDAIFIIDNIVNGFFAIDIILTFFVAYLDSHSYLLVDSPKKIAIRYLSTWFAFDVCSTAPFQPLSLLFNYELGFRILSMLRLWRLRRVSSLFARLEKDIRFNYFWIRCTKLISVTLFAIHCAGCFNYLIADRYPNPRKTWIGAVYPNFKEASLWNRYVTALYWSITTLTTTGYGDFHAENPREMLFDIFFMMFNLGLTAYLIGNMTNLVVHWTSRTRTFRDSVRAASEFASRNQLPHDIQDQMLSHICLKFKTEGLKQQETLNNLPKAIRSSIANYLFFPIVHNIYLFQGVSRNFLFQLVSDIDAEYFPPKEDIILQNEAPTDLYILVSGAVDFTVYVDGHDQFQGKAVIGETFGEVGVLYYRPQPFTVRTTELSQILRISRTSLMSAMHAHADDGRVIMNNLFMKLR 6v4a A 3.83 BS01 P3A A 1 N560 G565 L567 R569 D577 N513 G518 L520 R522 D530 V4JF97 GRVQHFTGYIEDGRGIFYSLPDMKQGDIIYASMQNTGGNLDPLVGIMAEEIDPAVSLGQVLEKALASENDLISELTAVADRIFLGWDDDGGKGYSASLEFTIPRDGTYHIFAGSTITNQRLDKFQPTYTTGSFQLILGLNAPQVISGEGEPEGEVFASLAIKPEAHVQELEIRLDKDTRYLTQHTRNLQPGDTFHALVEPIGEAPLPRLRLTDSGGKPLAFGLIDQPGESVELNYTCDQDICELVVHVDGTDGQKDSGEAVYRLLVGINAPNLSSVFLESDLVTVGLAVDQIVGVDQRSENFSVVGTLKLSWHDPKLGFSPDQCGCTVKSFEDASIRAVAGEINLPLPSFSFYNQQGNRWSQNQVIFVTPDGRASYFERFTVTLQAPDFDFLAYPFDRQKFSIKVDLAVPTNMFIFNEIERFQQVVGDQLGEEEWVVTSYSQEITEVPFERGSTNSRFTTTLLVKRNLEYYILRIFVPLFLIISVSWVIFFLKDYGRQLEVASGNLLVFVAFNFTISGDLPRLGYLTVLDRFMIVSFCLTAIVVLISVCQKRLGAVGKQAVAAQIDTWVLVIYPLVYSLYIIWVYLRFF 6v4a E 3.83 BS01 P3A E 1 N560 D577 N516 D533 V4JF97 GRVQHFTGYIEDGRGIFYSLPDMKQGDIIYASMQNTGGNLDPLVGIMAEEIDPAVSLGQVLEKALASENDLISELTAVADRIFLGWDDDGGKGYSASLEFTIPRDGTYHIFAGSTITNQRLDKFQPTYTTGSFQLILGLNAPQVISGEGEPEGEVFASLAKPEAHVQELEIRLDKDTRYLTQHTRNLQPGDTFHALVEPIGEAPLPRLRLTDSGGKPLAFGLIDQPGESVELNYTCDQDICELVVHVDGTDGQKDSGEAVYRLLVGINAPNLRESGSSVFLESDLVTVGLAVDQIVGVDQRSENFSVVGTLKLSWHDPKLGFSPDQCGCTVKSFEDASIRAVAGEINLPLPSFSFYNQQGNRWSQNQVIFVTPDGRASYFERFTVTLQAPDFDFLAYPFDRQKFSIKVDLAVPTNMFIFNEIERFQQVVGDQLGEEEWVVTSYSQEITEVPFERGSTNSRFTTTLLVKRNLEYYILRIFVPLFLIISVSWVIFFLKDYGRQLEVASGNLLVFVAFNFTISGDLPRLGYLTVLDRFMIVSFCLTAIVVLISVCQKRLGAVGKQAVAAQIDTWVLVIYPLVYSLYIIWVYLRFF 6v4a C 3.83 BS01 P3A B 1 L567 R569 L524 R526 V4JF97 GRVQHFTGYIEDGRGIFYSLPDMKQGDIIYASMQNTGGNLDPLVGIMAEEIDPAVSLGQVLEKALASENDLISELTAVADRIFLGWDDDGGKGYSASLEFTIPRDGTYHIFAGSTITNQRLDKFQPTYTTGSFQLILGLNAPQVISGEGEPEGEVFASLAIKPEAHVQELEIRLDKDTRYLTQHTRNLQPGDTFHALVEPIGEAPLPRLRLTDSGGKPLAFGLIDQPGESVELNYTCDQDICELVVHVDGTDGQKDSGEAVYRLLVGINAPNLRESGSSVFLESDLVTVGLAVDQIVGVDQRSENFSVVGTLKLSWHDPKLGFSPDQCGCTVKSFEDASIRAVAGEINLPLPSFSFYNQQGNRWSQNQVIFVTPDGRASYFERFTVTLQAPDFDFLAYPFDRQKFSIKVDLAVPTNMFIFNEIERFQQVVGDQLGEEEWVVTSYSQEITEVPFERGSTNSRFTTTLLVKRNLEYYILRIFVPLFLIISVSWVIFFLKDYGRQLEVASGNLLVFVAFNFTISGDLPRLGYLTVLDRFMIVSFCLTAIVVLISVCQKRLGAVGKQAVAAQIDTWVLVIYPLVYSLYIIWVYLRFF 6v4a B 3.83 BS01 P3A A 2 Y441 G565 L567 D577 Y394 G518 L520 D530 V4JF97 GRVQHFTGYIEDGRGIFYSLPDMKQGDIIYASMQNTGGNLDPLVGIMAEEIDPAVSLGQVLEKALASENDLISELTAVADRIFLGWDDDGGKGYSASLEFTIPRDGTYHIFAGSTITNQRLDKFQPTYTTGSFQLILGLNAPQVISGEGEPEGEVFASLAIKPEAHVQELEIRLDKDTRYLTQHTRNLQPGDTFHALVEPIGEAPLPRLRLTDSGGKPLAFGLIDQPGESVELNYTCDQDICELVVHVDGTDGQKDSGEAVYRLLVGINAPNLSSVFLESDLVTVGLAVDQIVGVDQRSENFSVVGTLKLSWHDPKLGFSPDQCGCTVKSFEDASIRAVAGEINLPLPSFSFYNQQGNRWSQNQVIFVTPDGRASYFERFTVTLQAPDFDFLAYPFDRQKFSIKVDLAVPTNMFIFNEIERFQQVVGDQLGEEEWVVTSYSQEITEVPFERGSTNSRFTTTLLVKRNLEYYILRIFVPLFLIISVSWVIFFLKDYGRQLEVASGNLLVFVAFNFTISGDLPRLGYLTVLDRFMIVSFCLTAIVVLISVCQKRLGAVGKQAVAAQIDTWVLVIYPLVYSLYIIWVYLRFF 6v4a B 3.83 BS02 P3A B 1 Y517 T562 Y470 T515 V4JF97 GRVQHFTGYIEDGRGIFYSLPDMKQGDIIYASMQNTGGNLDPLVGIMAEEIDPAVSLGQVLEKALASENDLISELTAVADRIFLGWDDDGGKGYSASLEFTIPRDGTYHIFAGSTITNQRLDKFQPTYTTGSFQLILGLNAPQVISGEGEPEGEVFASLAIKPEAHVQELEIRLDKDTRYLTQHTRNLQPGDTFHALVEPIGEAPLPRLRLTDSGGKPLAFGLIDQPGESVELNYTCDQDICELVVHVDGTDGQKDSGEAVYRLLVGINAPNLSSVFLESDLVTVGLAVDQIVGVDQRSENFSVVGTLKLSWHDPKLGFSPDQCGCTVKSFEDASIRAVAGEINLPLPSFSFYNQQGNRWSQNQVIFVTPDGRASYFERFTVTLQAPDFDFLAYPFDRQKFSIKVDLAVPTNMFIFNEIERFQQVVGDQLGEEEWVVTSYSQEITEVPFERGSTNSRFTTTLLVKRNLEYYILRIFVPLFLIISVSWVIFFLKDYGRQLEVASGNLLVFVAFNFTISGDLPRLGYLTVLDRFMIVSFCLTAIVVLISVCQKRLGAVGKQAVAAQIDTWVLVIYPLVYSLYIIWVYLRFF 6v4s A 3.55 BS01 CA A 1 Q476 E479 Q422 E425 V4JF97 EGRVQHFTGYIEDGRGIFYSLPDMKQGDIIYASMQNTGGNLDPLVGIMAEEIDPAVSLGQVLEKALNDLISELTAVADRIFLGWDDDGGKGYSASLEFTIPRDGTYHIFAGSTITNQRLDKFQPTYTTGSFQLILGLNAPQVISGEGEPEGEVFASLASKPEAHVQELEIRLDKDTRYLTQHTRNLQPGDTFHALVEPIGEAPLPRLRLTDSGGKPLAFGLIDQPGESVELNYTCDQDICELVVHVDGTDGQKDSGEAVYRLLVGINSVFLESDLVTVGLAVDQIVGVDQRSENFSVVGTLKLSWHDPKLGFSPDQCGCTVKSFEDASIRAVAGEINLPLPSFSFYNQQGNRWSQNQVIFVTPDGRASYFERFTVTLQAPDFDFLAYPFDRQKFSIKVDLAVPTNMFIFNEIERFQQVVGDQLGEEEWVVTSYSQEITEVPFERGSTNSRFTTTLLVKRNLEYYILRIFVPLFLIISVSWVIFFLKDYGRQLEVASGNLLVFVAFNFTISGDLPRLGYLTVLDRFMIVSFCLTAIVVLISVCQKRLGAVGKQAVAAQIDTWVLVIYPLVYSLYIIWVYLRFFTDH 6v4s A 3.55 BS02 CA A 2 E347 P434 F436 E293 P380 F382 V4JF97 EGRVQHFTGYIEDGRGIFYSLPDMKQGDIIYASMQNTGGNLDPLVGIMAEEIDPAVSLGQVLEKALNDLISELTAVADRIFLGWDDDGGKGYSASLEFTIPRDGTYHIFAGSTITNQRLDKFQPTYTTGSFQLILGLNAPQVISGEGEPEGEVFASLASKPEAHVQELEIRLDKDTRYLTQHTRNLQPGDTFHALVEPIGEAPLPRLRLTDSGGKPLAFGLIDQPGESVELNYTCDQDICELVVHVDGTDGQKDSGEAVYRLLVGINSVFLESDLVTVGLAVDQIVGVDQRSENFSVVGTLKLSWHDPKLGFSPDQCGCTVKSFEDASIRAVAGEINLPLPSFSFYNQQGNRWSQNQVIFVTPDGRASYFERFTVTLQAPDFDFLAYPFDRQKFSIKVDLAVPTNMFIFNEIERFQQVVGDQLGEEEWVVTSYSQEITEVPFERGSTNSRFTTTLLVKRNLEYYILRIFVPLFLIISVSWVIFFLKDYGRQLEVASGNLLVFVAFNFTISGDLPRLGYLTVLDRFMIVSFCLTAIVVLISVCQKRLGAVGKQAVAAQIDTWVLVIYPLVYSLYIIWVYLRFFTDH 6vep E 2.90 BS01 III B 1 D12 R14 N15 L37 F39 K40 F64 R65 E97 K121 D9 R11 N12 L34 F36 K37 F61 R62 E94 K118 2.7.10.1 P06213 PGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6vep E 2.90 BS02 III F 1 R14 L36 L37 L62 F64 F88 F89 Y91 V94 F96 E97 R118 K121 R11 L33 L34 L59 F61 F85 F86 Y88 V91 F93 E94 R115 K118 2.7.10.1 P06213 PGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6vep K 2.90 BS01 III H 1 D12 R14 N15 L37 F39 K40 R65 E97 K121 D9 R11 N12 L34 F36 K37 R62 E94 K118 2.7.10.1 P06213 PGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6vep K 2.90 BS02 III L 1 R14 L36 L37 F64 F88 F89 Y91 V94 F96 R118 K121 R11 L33 L34 F61 F85 F86 Y88 V91 F93 R115 K118 2.7.10.1 P06213 PGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6vep K 2.90 BS03 FUC K 1 R252 V254 F258 R244 V246 F250 2.7.10.1 P06213 PGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6vep Q 2.90 BS01 III N 1 D12 R14 N15 L37 F39 K40 R65 K121 D8 R10 N11 L33 F35 K36 R61 K117 2.7.10.1 P06213 GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDECGDICPGTAKGKTNCPATVGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPK 6vep W 2.90 BS02 III X 1 R14 L37 F88 F89 Y91 V94 F96 R118 K121 R11 L34 F85 F86 Y88 V91 F93 R115 K118 2.7.10.1 P06213 PGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6veq E 3.25 BS01 III B 1 N15 L37 F39 R65 N11 L33 F35 R61 2.7.10.1 P06213 GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6veq E 3.25 BS02 III F 1 D12 R14 L36 F88 F89 Y91 V94 F96 R118 K121 D8 R10 L32 F84 F85 Y87 V90 F92 R114 K117 2.7.10.1 P06213 GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6veq K 3.25 BS02 III H 1 N15 L37 F39 F64 R65 N11 L33 F35 F60 R61 2.7.10.1 P06213 GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6veq K 3.25 BS03 FUC K 1 C253 V254 C241 V242 2.7.10.1 P06213 GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCP 6vrf A 1.50 BS01 ADP A 1 I35 A48 K50 C78 M94 Q95 L96 Q97 N100 S145 N146 D163 I24 A37 K39 C67 M83 Q84 L85 Q86 N89 S134 N135 D152 2.7.11.1 Q6IQ55 32424773 DILSVGILVKERWKVLRKIGGGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 6vrf A 1.50 BS02 MG A 1 N146 D163 N135 D152 2.7.11.1 Q6IQ55 32424773 DILSVGILVKERWKVLRKIGGGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 6vrz A 2.00 BS01 CLM A 1 Y30 L62 L119 E150 S232 L236 Q357 Y17 L49 L106 E137 S219 L223 Q344 P0AEY8 32127561 QALLFPLCLVLYTFSTYIGNMMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVELIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWLSLMVIFLK 6vs0 A 2.10 BS01 CLM A 1 Y30 L62 L119 S232 L236 I327 N331 Q357 F361 Y17 L49 L106 S219 L223 I314 N318 Q344 F348 P0AEY8 32127561 QALLFPLCLVLYTFSTYIGNMMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVELIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWLSLMVIFLK 6vs1 A 3.00 BS01 DXC A 1 Q69 E150 S232 N272 N331 A332 V335 Q357 Q56 E137 S219 N259 N318 A319 V322 Q344 P0AEY8 32127561 QALLFPLCLVLYTFSTYIGNMMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVELIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWLSLMVIFLK 6vua A 1.50 BS01 ROJ A 1 W125 S126 R127 K129 E146 D155 D156 S186 W189 S193 S220 T221 F222 E226 W80 S81 R82 K84 E101 D110 D111 S141 W144 S148 S175 T176 F177 E181 3.2.2.6,2.4.99.20 P28907 WRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCDITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFATSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLDGSRSKIFDKDSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI 6vur A 2.20 BS01 ROG A 1 D26 A33 W36 R37 V40 S83 F84 E401 F402 D24 A31 W34 R35 V38 S77 F78 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vus A 2.28 BS01 RNV A 1 F24 D26 A33 W36 V40 L63 M65 S83 F84 E401 F402 F22 D24 A31 W34 V38 L57 M59 S77 F78 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vus A 2.28 BS02 RNV A 2 W182 L241 R242 A243 H249 I268 T269 H270 D273 P274 W176 L235 R236 A237 H243 I262 T263 H264 D267 P268 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vut A 2.73 BS01 RN7 A 1 D26 I28 A33 W36 V40 L63 M65 S83 F84 E401 F402 D24 I26 A31 W34 V38 L57 M59 S77 F78 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vuu A 2.60 BS01 RNJ A 1 W13 D26 I28 A33 W36 R37 L63 M65 S83 F84 H119 E401 F402 W11 D24 I26 A31 W34 R35 L57 M59 S77 F78 H113 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vuw A 2.87 BS01 RNM A 1 W13 D26 I28 A33 W36 R37 L63 S83 F84 E401 F402 W11 D24 I26 A31 W34 R35 L57 S77 F78 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vux A 1.97 BS01 H66 A 1 W13 F17 F24 D26 A33 W36 R37 M65 S83 F84 E401 F402 W11 F15 F22 D24 A31 W34 R35 M59 S77 F78 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vuy A 2.70 BS01 RN4 A 1 W13 M16 A33 W36 R37 V40 L63 M65 S83 F84 E401 F402 W11 M14 A31 W34 R35 V38 L57 M59 S77 F78 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vuy A 2.70 BS02 MG A 1 A134 S358 L359 L361 G362 A363 A128 S352 L353 L355 G356 A357 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vuz A 2.65 BS01 RMS A 1 D26 I28 A33 W36 M65 S83 F84 H119 E401 F402 D24 I26 A31 W34 M59 S77 F78 H113 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vv1 A 2.45 BS01 RMJ A 1 F24 D26 A33 W36 M65 S83 F84 E401 F402 F22 D24 A31 W34 M59 S77 F78 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6vv2 A 2.95 BS01 RMG A 1 D26 A33 W36 R37 V40 L63 M65 S83 F84 H119 E401 F402 D24 A31 W34 R35 V38 L57 M59 S77 F78 H113 E395 F396 2.3.1.- P9WFK7 32421305 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 6w6w A 3.00 BS01 NUC E 1 C928 Y949 E951 S977 R978 S979 N981 Y983 E1162 R1163 K1164 K1167 C641 Y662 E664 S690 R691 S692 N694 Y696 E862 R863 K864 K867 Q2NKJ3 SCELIDLDLSWLGHLFLFPRWSYLPPARWNSSGEGHLELWDAPVPQRNLAGSLVRLSALVKSKQKAYFILSLGRVSIIVQVPAQLVWHRALRPGTAYVLTELRVSKIRGQRQHVWMTSQSSRLLVRYSRLLSYSGAVTGVLNEPAGLYELDGQLGLCLAYQQFRGLRRVMRPGVCLQLQDVHLLQSVGGGTRRPVLAPCLRGAVLLQSFSRQKPGAHSSRQAYGASLYEQLVWERQLGLPLYLWATKALEELACKLCPHVLRHHQFLQHSSPGSPSLGLQLLAPTLDLLAPPGSPVRNAHNEILEEPHHCPLQKYTRLQTPSSFPTLATLKEEGQRKAWASFDPKALLPLPEASYLPSCQLNRRLAWSWLCLLPSAFCPAQVLLGVLVASSHKGCLQLRDQSGSLPCLLLAKHSQPLSDPRLIGCLVRAERFQLIVERDVRSSFPSWKELSMPGFIQKQQARVYVQFFLADALILPVPRPPHLGQSRLFLLCHKEALMKRNFCVPPGASPEVPKPALSFYVLGSWLGGTQRKEGTGWGLPEPQDQKVHLIFFGSSVRWFEFLHPGQVYRLIAPGPATPMLFEKDRRPLELAGCASCLTVQDNWTLELESLPESSLTDLLSDNFTDSLVSFSAEILSRTLCCVKLTVALETAECEFPPHLDVYIEDPHLPPSLGLLPGARVHFSQLEKRVSRSHNVYCCFRSSTYVQVLSFPPETTISIPLPHIYLAELLQGGQSPFQATASCHIVSVFSLQLFWVCAYCTSICRQGKCTRLGSTCPTQTAISQAIIRLLVEDGTAEAVVTCRNHHVAAALGLCPREWASLLDFVQVPGRVVLQFDEPMTMFLWTLCTSPSVLRPIVLSFELERKPSKIVPLEPPRLQRFQCGELPFLTHVNPRLRLSCLSIRESE 6w6w A 3.00 BS02 ZN A 1 C1043 C1046 C1055 C1062 C756 C759 C768 C775 Q2NKJ3 SCELIDLDLSWLGHLFLFPRWSYLPPARWNSSGEGHLELWDAPVPQRNLAGSLVRLSALVKSKQKAYFILSLGRVSIIVQVPAQLVWHRALRPGTAYVLTELRVSKIRGQRQHVWMTSQSSRLLVRYSRLLSYSGAVTGVLNEPAGLYELDGQLGLCLAYQQFRGLRRVMRPGVCLQLQDVHLLQSVGGGTRRPVLAPCLRGAVLLQSFSRQKPGAHSSRQAYGASLYEQLVWERQLGLPLYLWATKALEELACKLCPHVLRHHQFLQHSSPGSPSLGLQLLAPTLDLLAPPGSPVRNAHNEILEEPHHCPLQKYTRLQTPSSFPTLATLKEEGQRKAWASFDPKALLPLPEASYLPSCQLNRRLAWSWLCLLPSAFCPAQVLLGVLVASSHKGCLQLRDQSGSLPCLLLAKHSQPLSDPRLIGCLVRAERFQLIVERDVRSSFPSWKELSMPGFIQKQQARVYVQFFLADALILPVPRPPHLGQSRLFLLCHKEALMKRNFCVPPGASPEVPKPALSFYVLGSWLGGTQRKEGTGWGLPEPQDQKVHLIFFGSSVRWFEFLHPGQVYRLIAPGPATPMLFEKDRRPLELAGCASCLTVQDNWTLELESLPESSLTDLLSDNFTDSLVSFSAEILSRTLCCVKLTVALETAECEFPPHLDVYIEDPHLPPSLGLLPGARVHFSQLEKRVSRSHNVYCCFRSSTYVQVLSFPPETTISIPLPHIYLAELLQGGQSPFQATASCHIVSVFSLQLFWVCAYCTSICRQGKCTRLGSTCPTQTAISQAIIRLLVEDGTAEAVVTCRNHHVAAALGLCPREWASLLDFVQVPGRVVLQFDEPMTMFLWTLCTSPSVLRPIVLSFELERKPSKIVPLEPPRLQRFQCGELPFLTHVNPRLRLSCLSIRESE 6wbf A 2.83 BS01 CLR A 1 F116 I229 Y230 Y233 F115 I200 Y201 Y204 Q96RD7 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMI 6wbf A 2.83 BS02 CLR A 2 C228 I229 Y233 S236 C199 I200 Y204 S207 Q96RD7 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMI 6wbm A 2.86 BS01 CLR A 1 I229 S236 I197 S204 Q96RD7 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRADSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMI 6wbn A 2.83 BS01 CLR A 1 F116 Y230 F115 Y198 Q96RD7 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRADSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMI 6wbn A 2.83 BS02 CLR A 2 C228 I229 C196 I197 Q96RD7 AIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRADSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMI 6wej A 2.60 BS01 CPL A 1 D147 L148 C172 Y174 Y197 F200 W204 F207 M211 L359 D44 L45 C66 Y68 Y91 F94 W98 F101 M105 L253 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wej A 2.60 BS02 CPL A 2 V317 H321 T358 L360 Y363 V211 H215 T252 L254 Y257 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wej A 2.60 BS03 CPL A 3 W333 I387 L394 W227 I281 L288 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wej A 2.60 BS04 CPL A 4 I140 W322 L326 W329 I37 W216 L220 W223 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wej A 2.60 BS05 CPL A 5 Y287 V290 V311 W314 Y315 I318 Y181 V184 V205 W208 Y209 I212 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wek A 2.70 BS01 PCG A 1 C521 F558 G559 L561 S562 R575 T576 A577 C413 F450 G451 L453 S454 R467 T468 A469 Q03611 VRIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 6wek A 2.70 BS02 CPL A 1 Y134 D147 L148 C172 Y197 F200 W204 F207 Y32 D45 L46 C64 Y89 F92 W96 F99 Q03611 VRIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 6wek A 2.70 BS04 CPL A 3 L326 W329 I330 L218 W221 I222 Q03611 VRIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 6wek A 2.70 BS05 CPL A 4 Y132 I133 L294 W314 Y315 I318 Y30 I31 L186 W206 Y207 I210 Q03611 VRIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 6wek A 2.70 BS06 CPL A 5 I318 W322 L326 I210 W214 L218 Q03611 VRIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 6wek A 2.70 BS07 CPL A 6 V317 H321 T358 L359 L360 Y363 V209 H213 T250 L251 L252 Y255 Q03611 VRIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 6wek B 2.70 BS02 CPL B 1 Y134 D147 L148 C172 Y174 Y197 F200 W204 F207 Y32 D45 L46 C64 Y66 Y89 F92 W96 F99 Q03611 VRIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 6wek B 2.70 BS05 CPL B 4 I133 L136 V290 L294 W314 Y315 I318 I31 L34 V182 L186 W206 Y207 I210 Q03611 VRIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 6wek B 2.70 BS06 CPL B 5 Y315 I318 W322 L326 Y207 I210 W214 L218 Q03611 VRIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 6wel A 2.50 BS01 CPL A 1 D147 L148 P151 E171 C172 Y174 Y197 F200 W204 F207 L359 D44 L45 P48 E65 C66 Y68 Y91 F94 W98 F101 L253 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIVATIAGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wel A 2.50 BS02 CPL A 2 L137 V317 H321 T358 L359 L360 Y363 L34 V211 H215 T252 L253 L254 Y257 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIVATIAGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wel A 2.50 BS03 CPL A 3 W333 I387 W227 I281 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIVATIAGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wel A 2.50 BS04 CPL A 4 I140 Q143 W322 L326 W329 I37 Q40 W216 L220 W223 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIVATIAGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wel A 2.50 BS05 CPL A 5 L136 V290 R291 L294 V311 W314 Y315 I318 L33 V184 R185 L188 V205 W208 Y209 I212 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIVATIAGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wel A 2.50 BS06 CPL A 6 Y122 V130 I133 C293 Y19 V27 I30 C187 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIVATIAGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wel B 2.50 BS04 CPL B 4 I140 Q143 V144 W322 L326 W329 I37 Q40 V41 W216 L220 W223 Q03611 RIRKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIVATIAGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKK 6wfs A 4.60 BS01 U0A A 1 F23 P25 T33 W102 S106 F23 P25 T33 W102 S106 P03147 32369333 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILST 6wfs B 4.60 BS01 U0A B 1 P25 T33 W102 I105 S106 L140 P25 T33 W102 I105 S106 L140 P03147 32369333 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILST 6wfs C 4.60 BS01 U0A B 1 S121 V124 R127 T128 P138 S121 V124 R127 T128 P138 P03147 32369333 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILST 6wfs C 4.60 BS02 U0A C 1 F23 P25 T33 W102 I105 S106 I139 F23 P25 T33 W102 I105 S106 I139 P03147 32369333 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILST 6wfs D 4.60 BS01 U0A D 1 F23 P25 T33 S106 F23 P25 T33 S106 P03147 32369333 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILST 6wnq F 3.30 BS03 MG F 1 K155 T156 K156 T157 7.1.2.2 A0A192CEZ8 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6wnq E 3.30 BS02 ADP E 1 G152 G154 T156 V157 Y331 F404 A407 F410 T411 G153 G155 T157 V158 Y332 F405 A408 F411 T412 7.1.2.2 A0A192CEZ8 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6wnq D 3.30 BS01 ADP D 1 G152 V153 G154 K155 T156 V157 Y331 A407 F410 G153 V154 G155 K156 T157 V158 Y332 A408 F411 7.1.2.2 A0A192CEZ8 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6wnr C 3.30 BS02 ADP F 1 V374 R376 V373 R375 7.1.2.2 A0A073FQ32 QLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADAMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKATGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKAIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGAAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW 6wnr F 3.30 BS03 MG F 1 K155 R182 K156 R183 7.1.2.2 A0A192CEZ8 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6wnr E 3.30 BS02 ADP E 1 G152 G154 K155 T156 Y331 F404 A407 F410 T411 G153 G155 K156 T157 Y332 F405 A408 F411 T412 7.1.2.2 A0A192CEZ8 MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 6wny A 1.86 BS01 U64 A 1 G72 Q73 G74 L91 D93 G95 S96 Y132 F169 I171 I179 Y259 D289 S290 G291 T293 A396 G13 Q14 G15 L32 D34 G36 S37 Y73 F110 I112 I120 Y192 D222 S223 G224 T226 A329 3.4.23.46 P56817 FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI 6wqn H 2.90 BS01 NUC 2 1 R9 T14 R15 S16 K19 R22 V30 Y32 N38 Q78 T87 H88 R8 T13 R14 S15 K18 R21 V29 Y31 N37 Q77 T86 H87 A0A2X2JWH5 ASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAI 6wqn a 2.90 BS01 NUC 2 1 D6 K7 R11 H15 R19 R30 N32 Y34 R35 S36 N37 K38 Y41 Q43 T52 Q55 T68 K69 H102 G103 D3 K4 R8 H12 R16 R27 N29 Y31 R32 S33 N34 K35 Y38 Q40 T49 Q52 T59 K60 H93 G94 W8TRE0 KIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF 6wqq H 3.10 BS01 NUC 2 1 R15 S16 L18 K19 R22 V30 Y32 N38 Q78 H88 L92 R14 S15 L17 K18 R21 V29 Y31 N37 Q77 H87 L91 A0A2X2JWH5 ASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAI 6wqq a 3.10 BS01 NUC 2 1 K4 D6 K7 R11 H15 R19 N32 Y34 R35 S36 N37 K38 H39 Q43 I45 V51 T52 Q55 K59 A67 T68 V70 H102 G103 R104 K1 D3 K4 R8 H12 R16 N29 Y31 R32 S33 N34 K35 H36 Q40 I42 V48 T49 Q52 K56 A58 T59 V61 H93 G94 R95 W8TRE0 KIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF 6wrs H 3.20 BS01 NUC 2 1 R9 K12 T14 R15 S16 L18 K19 Y32 N38 Q78 H88 L92 R8 K11 T13 R14 S15 L17 K18 Y31 N37 Q77 H87 L91 A0A2X2JWH5 ASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAI 6wrs a 3.20 BS01 NUC 2 1 D6 K7 K9 R11 R19 R30 N32 Y34 R35 S36 N37 K38 Q43 V51 T52 Q55 A67 T68 V70 H102 G103 R104 D3 K4 K6 R8 R16 R27 N29 Y31 R32 S33 N34 K35 Q40 V48 T49 Q52 A58 T59 V61 H93 G94 R95 W8TRE0 KIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF 6wru H 3.10 BS01 NUC 2 1 R9 K12 T14 R15 S16 K19 Q20 R22 V30 Y32 G33 K37 N38 S40 Q78 T87 H88 D90 L92 R8 K11 T13 R14 S15 K18 Q19 R21 V29 Y31 G32 K36 N37 S39 Q77 T86 H87 D89 L91 A0A2X2JWH5 ASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAI 6wru a 3.10 BS01 NUC 2 1 K4 D6 K7 K9 R11 H15 R19 R30 N32 Y34 R35 S36 N37 Y41 Q43 I45 V51 T52 Q55 T68 K69 V70 L100 H102 G103 R104 K1 D3 K4 K6 R8 H12 R16 R27 N29 Y31 R32 S33 N34 Y38 Q40 I42 V48 T49 Q52 T65 K66 V67 L97 H99 G100 R101 W8TRE0 KIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF 6x4i A 1.85 BS01 U3P A 1 H235 G247 G248 H250 K290 W333 T341 Y343 H236 G248 G249 H251 K291 W334 T342 Y344 3.1.-.- P0DTD1 AMSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 6xvw A 2.00 BS01 O3H A 1 D766 D770 H862 G863 N868 R878 I879 Y896 K903 S904 Y907 E988 D103 D107 H196 G197 N202 R212 I213 Y230 K237 S238 Y241 E322 2.4.2.30,2.4.2.- P09874 32435397 HMSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 6xvw B 2.00 BS01 O3H B 1 D766 N767 L769 D770 H862 G863 N868 R878 Y896 K903 S904 Y907 E988 D101 N102 L104 D105 H197 G198 N203 R213 Y231 K238 S239 Y242 E323 2.4.2.30,2.4.2.- P09874 32435397 HMSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 6ymd A 1.25 BS01 PMP A 1 S98 G99 A100 H127 Y176 S177 D202 A204 H205 T228 H230 K231 S96 G97 A98 H125 Y174 S175 D200 A202 H203 T226 H228 K229 2.1.2.1 I7H6W6 32417544 QTNLDFLLQTDPTISGMMQKELQRQREHLELIASENFTSPAVMATQGSVLTNKYAEGLPKKRYYGGCEFIDEIEQVAIDRAKELFGAASANVQPHSGAQANFAVFLTLLKPGDKIMGMDLSHGGHLTHGSPANVSGKWFEAVHYGVSQETEQLDYDHILEVARQERPKLIICGYSAYPRIINFEKFRAIADEVGAYLLADIAHIAGLVASGHHPNPVPHCDVVTTTTHKTLRGPRGGLILTRDPELGKKFNKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFKAYSGQVIANAQAMAQQLQNRGFKIVSGGTDNHLMLVDLRSVNLTGKQADQLVSDVNITANKNTVPFDPESPFVTSGLRLGSPAMTTRGLGTEDFAEIANIIADRLQNPEDEQVKQACVQRVAALCERFPLYPHLNAP 6ymd A 1.25 BS02 MLI A 1 Y56 E58 Y66 Y54 E56 Y64 2.1.2.1 I7H6W6 32417544 QTNLDFLLQTDPTISGMMQKELQRQREHLELIASENFTSPAVMATQGSVLTNKYAEGLPKKRYYGGCEFIDEIEQVAIDRAKELFGAASANVQPHSGAQANFAVFLTLLKPGDKIMGMDLSHGGHLTHGSPANVSGKWFEAVHYGVSQETEQLDYDHILEVARQERPKLIICGYSAYPRIINFEKFRAIADEVGAYLLADIAHIAGLVASGHHPNPVPHCDVVTTTTHKTLRGPRGGLILTRDPELGKKFNKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFKAYSGQVIANAQAMAQQLQNRGFKIVSGGTDNHLMLVDLRSVNLTGKQADQLVSDVNITANKNTVPFDPESPFVTSGLRLGSPAMTTRGLGTEDFAEIANIIADRLQNPEDEQVKQACVQRVAALCERFPLYPHLNAP 6ymd A 1.25 BS03 MLI B 1 S36 H127 S177 H205 K231 R363 S34 H125 S175 H203 K229 R361 2.1.2.1 I7H6W6 32417544 QTNLDFLLQTDPTISGMMQKELQRQREHLELIASENFTSPAVMATQGSVLTNKYAEGLPKKRYYGGCEFIDEIEQVAIDRAKELFGAASANVQPHSGAQANFAVFLTLLKPGDKIMGMDLSHGGHLTHGSPANVSGKWFEAVHYGVSQETEQLDYDHILEVARQERPKLIICGYSAYPRIINFEKFRAIADEVGAYLLADIAHIAGLVASGHHPNPVPHCDVVTTTTHKTLRGPRGGLILTRDPELGKKFNKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFKAYSGQVIANAQAMAQQLQNRGFKIVSGGTDNHLMLVDLRSVNLTGKQADQLVSDVNITANKNTVPFDPESPFVTSGLRLGSPAMTTRGLGTEDFAEIANIIADRLQNPEDEQVKQACVQRVAALCERFPLYPHLNAP 6ymd A 1.25 BS04 PMP B 1 Y56 G262 G263 Y54 G260 G261 2.1.2.1 I7H6W6 32417544 QTNLDFLLQTDPTISGMMQKELQRQREHLELIASENFTSPAVMATQGSVLTNKYAEGLPKKRYYGGCEFIDEIEQVAIDRAKELFGAASANVQPHSGAQANFAVFLTLLKPGDKIMGMDLSHGGHLTHGSPANVSGKWFEAVHYGVSQETEQLDYDHILEVARQERPKLIICGYSAYPRIINFEKFRAIADEVGAYLLADIAHIAGLVASGHHPNPVPHCDVVTTTTHKTLRGPRGGLILTRDPELGKKFNKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFKAYSGQVIANAQAMAQQLQNRGFKIVSGGTDNHLMLVDLRSVNLTGKQADQLVSDVNITANKNTVPFDPESPFVTSGLRLGSPAMTTRGLGTEDFAEIANIIADRLQNPEDEQVKQACVQRVAALCERFPLYPHLNAP 6ymf A 1.63 BS01 PLS A 1 S36 S98 G99 A100 H127 S177 D202 A204 H205 T228 H230 K231 R363 S34 S96 G97 A98 H125 S175 D200 A202 H203 T226 H228 K229 R361 2.1.2.1 I7H6W6 32417544 QTNLDFLLQTDPTISGMMQKELQRQREHLELIASENFTSPAVMATQGSVLTNKYAEGLPKKRYYGGCEFIDEIEQVAIDRAKELFGAASANVQPHSGAQANFAVFLTLLKPGDKIMGMDLSHGGHLTHGSPANVSGKWFEAVHYGVSQETEQLDYDHILEVARQERPKLIICGYSAYPRIINFEKFRAIADEVGAYLLADIAHIAGLVASGHHPNPVPHCDVVTTTTHKTLRGPRGGLILTRDPELGKKFNKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFKAYSGQVIANAQAMAQQLQNRGFKIVSGGTDNHLMLVDLRSVNLTGKQADQLVSDVNITANKNTVPFDPESPFVTSGLRLGSPAMTTRGLGTEDFAEIANIIADRLQNPEDEQVKQACVQRVAALCERFPLYPHLN 6ypa A 1.58 BS01 P6W A 1 E42 Y48 K113 F117 E120 A146 F147 W149 N171 L172 V173 M174 E43 Y49 K114 F118 E121 A147 F148 W150 N172 L173 V174 M175 O58376 HMVKVGYIQMEPKILELDKNYSKAEKLIKEASKEGAKLVVLPELFDTGYNFESREEVFDVAQQIPEGETTTFLMELARELGLYIVAGTAEKSGNYLYNSAVVVGPRGYIGKYRKIHLFYREKVFFEPGDLGFKVFDIGFAKVGVMIAFDWFFPESARTLALKGAEIIAHPANLVMPYAPRAMPIRALENRVYTITADRVGEERGLKFIGKSLIASPKAEVLSIASETEEEIGVVEIDLNLARNKRLNDMNDIFKDRREEYYFR 6ype A 1.45 BS01 CA A 1 N280 E358 Q359 D360 N56 E134 Q135 D136 Q15818 GDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSATPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGATKWTFEACR 6ype A 1.45 BS02 CA A 2 E358 D360 D367 Q370 E134 D136 D143 Q146 Q15818 GDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSATPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGATKWTFEACR 6yrw A 2.50 BS02 DSN A 1 S35 H126 S176 H204 R363 S29 H120 S170 H198 R357 2.1.2.1 Q5MCK9 DYKAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKSAEGYPGKRYYGGTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAGGHLTHGAPVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGLILTDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALENHDKPEVLERIRGDVKVLTDAFPLY 6yrw B 2.50 BS02 DSN B 1 S35 H126 S176 H204 K230 R363 S29 H120 S170 H198 K224 R357 2.1.2.1 Q5MCK9 DYKAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKSAEGYPGKRYYGGTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAGGHLTHGAPVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGLILTDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALENHDKPEVLERIRGDVKVLTDAFPLY 6z4y A 2.25 BS01 Q7Q A 1 L139 G140 K141 G142 A160 K162 L194 L208 L210 E211 Y212 A213 T217 E260 N261 L263 A273 F275 L16 G17 K18 G19 A37 K39 L71 L85 L87 E88 Y89 A90 T94 E137 N138 L140 A150 F152 2.7.11.1 O14965 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 6z4z A 2.07 BS01 PQ5 A 1 L167 A189 K191 E206 F241 E242 L244 G245 E292 N293 L295 V324 D325 L22 A44 K46 E61 F96 E97 L99 G100 E147 N148 L150 V179 D180 2.7.12.1 P49759 SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKK 6z4z B 2.07 BS01 PQ5 B 1 L167 A189 K191 E206 F241 E242 L244 G245 L295 V324 D325 L22 A44 K46 E61 F96 E97 L99 G100 L150 V179 D180 2.7.12.1 P49759 SMHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKKSI 6z50 A 1.60 BS01 Q7K A 1 L167 G168 V175 A189 K191 V225 F241 E242 L244 D250 N293 L295 L19 G20 V27 A41 K43 V77 F93 E94 L96 D102 N145 L147 2.7.12.1 P49759 LICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLK 6z51 A 1.92 BS01 Q8B A 1 L162 G163 E164 F167 A184 F236 E237 L239 N242 E287 N288 L290 D320 L29 G30 E31 F34 A51 F103 E104 L106 N109 E154 N155 L157 D187 2.7.12.1 P49761 RSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHT 6z52 A 2.12 BS01 Q8T A 1 L162 E164 F167 V170 A184 K186 F236 E237 L239 N242 E245 E287 N288 L290 D320 L34 E36 F39 V42 A56 K58 F108 E109 L111 N114 E117 E159 N160 L162 D192 2.7.12.1 P49761 SKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSF 6z53 A 1.65 BS01 Q7Z A 1 L162 G163 E164 F167 A184 V220 F236 E237 L239 N242 E245 E287 N288 L290 D320 L29 G30 E31 F34 A51 V87 F103 E104 L106 N109 E112 E154 N155 L157 D187 2.7.12.1 P49761 RSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHT 6z54 A 1.73 BS01 Q7H A 1 L162 F167 A184 V220 F236 E237 L239 N242 E245 E287 N288 L290 D320 L29 F34 A51 V87 F103 E104 L106 N109 E112 E154 N155 L157 D187 2.7.12.1 P49761 RSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHT 6z55 A 1.70 BS01 PQ5 A 1 V170 A184 K186 F236 E237 L238 L239 L290 A319 D320 V46 A60 K62 F112 E113 L114 L115 L166 A195 D196 2.7.12.1 P49761 SMQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSF 6z55 B 1.70 BS01 PQ5 B 1 V170 A184 K186 F236 E237 L238 L239 L290 D320 V43 A57 K59 F109 E110 L111 L112 L163 D193 2.7.12.1 P49761 SSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHT 6z56 A 1.90 BS01 Q7Q A 1 I490 E492 G493 G496 V498 A509 K511 E535 S539 I557 F605 E606 G608 G609 L656 I686 D687 I21 E23 G24 G27 V29 A40 K42 E66 S70 I88 F136 E137 G139 G140 L187 I217 D218 2.7.11.1 Q8TF76 KGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 6z57 A 1.50 BS01 Q8W A 1 I490 E492 F495 V498 A509 K511 F605 E606 F607 G608 G609 L656 I686 D687 I21 E23 F26 V29 A40 K42 F136 E137 F138 G139 G140 L187 I217 D218 2.7.11.1 Q8TF76 KGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 6z58 A 1.80 BS01 Q9B A 1 I490 F495 V498 A509 K511 F605 E606 F607 G608 G609 L656 I686 D687 I21 F26 V29 A40 K42 F136 E137 F138 G139 G140 L187 I217 D218 2.7.11.1 Q8TF76 KGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 6z59 A 2.00 BS01 Q98 A 1 I490 G491 F495 V498 A509 K511 F605 E606 F607 G608 G609 N654 L656 I686 D687 I20 G21 F25 V28 A39 K41 F135 E136 F137 G138 G139 N184 L186 I216 D217 2.7.11.1 Q8TF76 GPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 6z5a A 1.55 BS02 Q8B A 1 I490 G491 E492 F495 V498 A509 K511 I513 I532 E535 I536 S539 I557 L603 F605 E606 F607 G608 G609 N654 L656 I686 D687 Y688 I33 G34 E35 F38 V41 A52 K54 I56 I75 E78 I79 S82 I100 L146 F148 E149 F150 G151 G152 N197 L199 I229 D230 Y231 2.7.11.1 Q8TF76 NLYFQSMGECSQKGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 6z5d A 1.75 BS01 Q8Q A 1 I490 G491 E492 V498 A509 K511 F605 E606 F607 G608 G609 L656 I686 D687 I21 G22 E23 V29 A40 K42 F136 E137 F138 G139 G140 L187 I217 D218 2.7.11.1 Q8TF76 KGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 6z5e A 1.50 BS01 Q8K A 1 I490 E492 F495 A509 K511 I557 F605 E606 F607 G608 G609 D611 L656 I686 D687 I20 E22 F25 A39 K41 I87 F135 E136 F137 G138 G139 D141 L186 I216 D217 2.7.11.1 Q8TF76 GPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 7bzf A 3.26 BS01 NUC F 1 N496 K500 K545 R555 V557 A558 R569 K577 G590 T591 S592 F594 Y595 S682 G683 D684 A685 Y689 S913 M924 N496 K500 K545 R555 V557 A558 R569 K577 G590 T591 S592 F594 Y595 S682 G683 D684 A685 Y689 S898 M909 2.7.7.48 P0DTD1 SADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTTSRYWEPEFYEAMYTPHT 7bzf A 3.26 BS02 NUC G 1 S759 D760 C813 S814 R836 K849 E857 R858 S861 S759 D760 C813 S814 R836 K849 E857 R858 S861 2.7.7.48 P0DTD1 SADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTTSRYWEPEFYEAMYTPHT 7bzf A 3.26 BS04 ZN A 2 C487 F571 H642 C645 C646 C487 F571 H642 C645 C646 2.7.7.48 P0DTD1 SADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTTSRYWEPEFYEAMYTPHT 7c2k A 2.93 BS01 NUC F 1 D499 K500 S501 N507 V557 A558 K577 G590 S592 F594 Y595 G683 D684 A685 Y689 R914 Y915 F920 M924 D499 K500 S501 N507 V557 A558 K577 G590 S592 F594 Y595 G683 D684 A685 Y689 R912 Y913 F918 M922 2.7.7.48 P0DTD1 SADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLDNTSRYWEPEFYEAMYTPHT 7c2k A 2.93 BS02 NUC G 1 K545 D623 S682 L758 S759 C813 S814 R836 A840 K849 R858 S861 D865 K545 D623 S682 L758 S759 C813 S814 R836 A840 K849 R858 S861 D865 2.7.7.48 P0DTD1 SADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLDNTSRYWEPEFYEAMYTPHT 7c2k D 2.93 BS01 NUC F 1 K61 R80 K9 R28 P0DTD1 AAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 7c49 A 2.25 BS01 FAD A 1 V59 G60 G62 F63 A64 L82 E83 A84 R85 G89 G90 R91 T92 F104 G105 G106 A107 W108 P278 V279 T307 V308 P309 W417 F422 A426 W427 G452 A453 A461 N462 I463 A466 V11 G12 G14 F15 A16 L34 E35 A36 R37 G41 G42 R43 T44 F56 G57 G58 A59 W60 P230 V231 T259 V260 P261 W369 F374 A378 W379 G404 A405 A413 N414 I415 A418 F8G0P2 KGGFDYDVVVVGGGFAGATAARECGLQGYRTLLLEARSRLGGRTFTSRFAGQEIEFGGAWVHWLQPHVWAEMQRYGLGVVEDPLTNLDKTLIMYNDGSVESISPDEFGKNIRIAFEKLCHDAWEVFPRPHEPMFTERARELDKSSVLDRIKTLGLSRLQQAQINSYMALYAGETTDKFGLPGVLKLFACGGWNYDAFMDTETHYRIQGGTIGLINAMLTDSGAEVRMSVPVTAVEQVNGGVKIKTDDDEIITAGVVVMTVPLNTYKHIGFTPALSKGKQRFIKEGQLSKGAKLYVHVKQNLGRVFAFADEQQPLNWVQTHDYSDELGTILSITIARKETIDVNDRDAVTREVQKMFPGVEVLGTAAYDWTADPFSLGAWAAYGVGQLSRLKDLQAAEGRILFAGAETSNGWHANIDGAVESGLRAGREVKQLLS 7c49 A 2.25 BS02 HNL A 1 L217 Y218 T250 W364 T381 W427 A461 L169 Y170 T202 W316 T333 W379 A413 F8G0P2 KGGFDYDVVVVGGGFAGATAARECGLQGYRTLLLEARSRLGGRTFTSRFAGQEIEFGGAWVHWLQPHVWAEMQRYGLGVVEDPLTNLDKTLIMYNDGSVESISPDEFGKNIRIAFEKLCHDAWEVFPRPHEPMFTERARELDKSSVLDRIKTLGLSRLQQAQINSYMALYAGETTDKFGLPGVLKLFACGGWNYDAFMDTETHYRIQGGTIGLINAMLTDSGAEVRMSVPVTAVEQVNGGVKIKTDDDEIITAGVVVMTVPLNTYKHIGFTPALSKGKQRFIKEGQLSKGAKLYVHVKQNLGRVFAFADEQQPLNWVQTHDYSDELGTILSITIARKETIDVNDRDAVTREVQKMFPGVEVLGTAAYDWTADPFSLGAWAAYGVGQLSRLKDLQAAEGRILFAGAETSNGWHANIDGAVESGLRAGREVKQLLS