5zjd A 2.39 BS01 NAI A 1 G28 A29 V30 D51 V52 I53 K56 T94 A95 G96 A97 R98 I115 I119 V135 N137 S160 L164 H192 T247 I251 G28 A29 V30 D51 V52 I53 K56 T94 A95 G96 A97 R98 I115 I119 V135 N137 S160 L164 H192 T247 I251 1.1.1.27 P00338 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 5zjd B 2.39 BS01 NAI B 1 G28 A29 V30 D51 V52 I53 K56 T94 A95 G96 A97 R98 N112 I115 I119 V135 N137 L164 H192 T247 I251 G28 A29 V30 D51 V52 I53 K56 T94 A95 G96 A97 R98 N112 I115 I119 V135 N137 L164 H192 T247 I251 1.1.1.27 P00338 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 5zjd C 2.39 BS01 NAI C 1 G28 A29 V30 D51 V52 I53 T94 A95 G96 R98 Q99 I115 F118 I119 V135 N137 S160 H192 T247 I251 G28 A29 V30 D51 V52 I53 T94 A95 G96 R98 Q99 I115 F118 I119 V135 N137 S160 H192 T247 I251 1.1.1.27 P00338 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 5zjf A 2.60 BS01 9G9 C 1 R170 S183 H185 W187 N204 A206 R170 S183 H185 W187 N204 A206 1.1.1.27 P00338 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 5zjf C 2.60 BS01 9G9 C 1 R170 S183 H185 W187 N204 A206 G207 V269 R170 S183 H185 W187 N204 A206 G207 V269 1.1.1.27 P00338 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 6a7x A 2.15 BS01 NAD A 1 S355 P356 I357 Y392 R393 A459 D460 L495 P500 R507 S328 P329 I330 Y365 R366 A432 D433 L468 P473 R480 1.17.1.4,1.17.3.2 P22985 ADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQKLHPVQERIARSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQASTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFGASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSAFKQASRREADIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNEELLQSVCAGLAEELQLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMCGKLDPTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDEVTCVGHIIGAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDLKKGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPDNRIVVRVKRMGGGFGGKETRSTVVSTALALAAHKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAASASADLNGQGVYEACQTILKRLEPFKKKKPTGPWEAWVMDAYTSAVSLSATGFYKTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQHKQLFQLDSPATPEKIRNACVDQFTTLCVTCKSWSVRI 6a7x A 2.15 BS06 FAD A 1 E45 G46 K255 L256 V257 V258 G259 N260 T261 E262 I263 A300 F336 A337 V341 A345 S346 G349 N350 I352 T353 S358 D359 L403 K421 D429 E43 G44 K228 L229 V230 V231 G232 N233 T234 E235 I236 A273 F309 A310 V314 A318 S319 G322 N323 I325 T326 S331 D332 L376 K394 D402 1.17.1.4,1.17.3.2 P22985 ADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQKLHPVQERIARSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQASTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFGASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSAFKQASRREADIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNEELLQSVCAGLAEELQLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMCGKLDPTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDEVTCVGHIIGAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDLKKGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPDNRIVVRVKRMGGGFGGKETRSTVVSTALALAAHKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAASASADLNGQGVYEACQTILKRLEPFKKKKPTGPWEAWVMDAYTSAVSLSATGFYKTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQHKQLFQLDSPATPEKIRNACVDQFTTLCVTCKSWSVRI 6a7x B 2.15 BS03 NAD B 1 P356 Y392 R393 G457 A459 D460 P500 R507 P327 Y363 R364 G428 A430 D431 P471 R478 1.17.1.4,1.17.3.2 P22985 ADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQKLHPVQERIARSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQASTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFGASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSAFKQASRREADIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNEELLQSVCAGLAEELQLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMCGKLDPTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDEVTCVGHIIGAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDLKKGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPDNRIVVRVKRMGGGFGGKETRSTVVSTALALAAHKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAASASADLNGQGVYEACQTILKRLEPFKKKKPTGPWEAWVMDAYTSAVSLSATGFYKTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQHGDNAKQLFQLDSPATPEKIRNACVDQFTTLCVTGV 6a9k L 1.90 BS01 9T0 H 1 F89 T91 V94 P96 F94 T96 V99 P101 DLLMAQTPLSLPVSLGDQASISCRSSQSLVHSSGNTYLEWYLQKPGQSPKLLIYKISNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCFQTSHVPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 6a9k H 1.90 BS01 9T0 H 1 I33 S35 W47 T50 S52 Y56 Y58 R95 Y97 Y98 F100a I33 S35 W47 T50 S52 Y57 Y59 R99 Y101 Y102 F105 EVMLVESGGGLVKPGGSLKLSCAASEFTFSTYIMSWVRQTPEKRLEWVATISSSGTYTYYRDSVKGRFTVSRDNANNILYLQMSSLRSEDTALYYCARRDYYDGFTYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDC 6a9k B 1.90 BS01 9T0 B 1 I33 W47 T50 S52 Y56 Y58 R95 Y97 Y98 F100a I33 W47 T50 S52 Y57 Y59 R99 Y101 Y102 F105 EVMLVESGGGLVKPGGSLKLSCAASEFTFSTYIMSWVRQTPEKRLEWVATISSSGTYTYYRDSVKGRFTVSRDNANNILYLQMSSLRSEDTALYYCARRDYYDGFTYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDC 6aar A 1.95 BS01 9TF A 1 L19 G20 S21 V27 K42 I77 V96 I160 D161 L18 G19 S20 V26 K41 I76 V95 I152 D153 2.7.11.1 P53355 TVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKP 6aaw A 2.00 BS01 III B 1 L54 F55 G58 Q59 I61 M62 Y67 Q72 H73 V93 I99 Y100 L29 F30 G33 Q34 I36 M37 Y42 Q47 H48 V68 I74 Y75 2.3.2.27 Q00987 TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVN 6ace A 1.98 BS01 III B 1 Y102 R105 I142 H158 V221 W222 F223 G224 E225 N226 V253 V254 Y255 Y67 R70 I107 H123 V186 W187 F188 G189 E190 N191 V218 V219 Y220 3.5.1.- Q9NXA8 PSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6acl A 1.92 BS01 III B 1 R71 Q83 A86 Y102 R105 I142 V221 F223 G224 E225 N226 L227 L232 V253 V254 Y255 P256 P280 R36 Q48 A51 Y67 R70 I107 V186 F188 G189 E190 N191 L192 L197 V218 V219 Y220 P221 P245 3.5.1.- Q9NXA8 PSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6aco A 1.71 BS01 III B 1 Q83 Y102 R105 I142 H158 V220 V221 W222 F223 G224 E225 N226 L227 L232 V253 V254 Y255 Q51 Y70 R73 I110 H126 V188 V189 W190 F191 G192 E193 N194 L195 L200 V221 V222 Y223 3.5.1.- Q9NXA8 SARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6acp A 2.30 BS01 III B 1 Q83 A86 Y102 R105 I142 V220 V221 W222 F223 G224 E225 N226 L227 L232 V253 V254 Y255 P256 Q46 A49 Y65 R68 I105 V183 V184 W185 F186 G187 E188 N189 L190 L195 V216 V217 Y218 P219 3.5.1.- Q9NXA8 PSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6cv1 A 2.76 BS01 III D 1 I1 E2 S3 I4 I5 K6 T31 A33 T34 S55 L58 E60 N61 S64 D116 T183 P185 K244 H245 P251 I1 E2 S3 I4 I5 K6 T31 A33 T34 S55 L58 E60 N61 S64 D116 T178 P180 K239 H240 P246 A0A0X7Z9B1 IESIIKTATDTVKSEINAELGVVPSLNAVETGATSNTEPEEAIQTRTVINQHGVSETLVENFLSRAALVSKRSFEYKDHTSSAAQTDKNFFKWTINTRSFVQLRRKLELFTYLRFDAEITILTTVAVNTYMGLPNLTLQAMFVPTGALTPEKQDSFHWQSGSNASVFFKISDPPARMTIPFMCINSAYSVFYDGFAGFEKSGLYGINPADTIGNLCVRIVNEHQPVGFTVTVRVYMKPKHIKAWAPRPPRTLPYMSIANANYKGKKRAPNALNAIIGNRDSVKTMPHNIV 6cv1 B 2.76 BS01 III D 1 D18 H19 S20 S21 A22 P23 L25 P26 C27 G38 Q39 V40 R41 N42 E45 Q48 V49 D18 H19 S20 S21 A22 P23 L25 P26 C27 G38 Q39 V40 R41 N42 E45 Q48 V49 E9RIT6 GVPTYLLPGSGQFLTTDDHSSAPVLPCFNPTPEMHIPGQVRNMLEVVQVESMMEINNTESAVGMERLKVDISALTDVDQLLFNIPLDIQLDGPLRNTLVGNISRYYTHWSGSLEMTFMFCGSFMATGKLILCYTPPGGSCPTTRETAMLGTHIVWDFGLQSSVTLIIPWISGSHYRMFNNDAKSTNANVGYVTCFMQTNLIVPSESSDTCSLIGFIAAKDDFSLRLMRDSPDIGQIDHLHAAEAAYQ 6cv1 C 2.76 BS01 III D 1 N30 Y31 C33 Y35 N21 Y22 C24 Y26 A0A097ZN88 SDRVLQLKLGNSAIVTQEAANYCCAYGEWPNYLPDHEAVAIDKPTQPETATDRFYTLKSVKWEAGSTGWWWKLPDALNNIGMFGQNVQHHYLYRSGFLIHVQCNATRFHQGALLVVAIPEHQRGAHNTNTSPGFDDIMKGEEGGTFNHPYVLDDGTSLACATIFPHQWINLRTNNSATIVLPWMNAAPMDFPLRHNQWTLAIIPVVPLGTRTMSSMVPITVSIAPMCCEFNGLRHAI 6cvb A 2.43 BS01 4U1 B 1 K270 P274 N275 G282 K264 P268 N269 G276 A0A0X7Z9B1 IESIIKTATDTVKSEINAELGVVSLNAVETGATSNTEPEEAIQTRTVINQHGVSETLVENFLSRAALVSKRSFEYKDHTSSAAQTDKNFFKWTINTRSFVQLRRKLELFTYLRFDAEITILTTVAVNTYMGLPNLTLQAMFVPTGALTPEKQDSFHWQSGSNASVFFKISDPPARMTIPFMCINSAYSVFYDGFAGFEKSGLYGINPADTIGNLCVRIVNEHQPVGFTVTVRVYMKPKHIKAWAPRPPRTLPYMSIANANYKGKKRAPNALNAIIGNRDSVKTMPHNIVT 6cvb B 2.43 BS01 4U1 B 1 D91 R95 R104 N180 P231 D232 I233 G234 D91 R95 R104 N180 P231 D232 I233 G234 E9RIT6 GVPTYLLPGSGQFLTTDDHSSAPVLPCFNPTPEMHIPGQVRNMLEVVQVESMMEINNTESAVGMERLKVDISALTDVDQLLFNIPLDIQLDGPLRNTLVGNISRYYTHWSGSLEMTFMFCGSFMATGKLILCYTPPGGSCPTTRETAMLGTHIVWDFGLQSSVTLIIPWISGSHYRMFNNDAKSTNANVGYVTCFMQTNLIVPSESSDTCSLIGFIAAKDDFSLRLMRDSPDIGQIDHLHAAEAAYQ 6e5f A 1.37 BS01 L6T A 1 Q152 G153 Q169 G171 G172 S173 T182 A184 L201 A203 M214 A217 Q97 G98 Q114 G116 G117 S118 T127 A129 L146 A148 M159 A162 O53780 GPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP 6e5s A 2.06 BS01 RET C 1 F16 I25 A33 Q38 K40 D51 F16 I25 A33 Q38 K40 D51 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKDKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 6e5s B 2.06 BS01 RET J 1 F16 M20 I25 A33 Q38 K40 D51 S55 F16 M20 I25 A33 Q38 K40 D51 S55 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKDKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 6e5s C 2.06 BS01 RET C 1 L77 W106 K108 L77 W106 K108 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKDKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 6e5s D 2.06 BS01 RET K 1 F16 Y19 M20 I25 Q38 K40 D51 T53 S55 F16 Y19 M20 I25 Q38 K40 D51 T53 S55 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKDKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 6e5s E 2.06 BS01 RET L 1 F16 M20 I25 Q38 K40 D51 F16 M20 I25 Q38 K40 D51 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKDKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 6e5s F 2.06 BS01 RET H 1 F16 I25 Q38 K40 D51 T53 F16 I25 Q38 K40 D51 T53 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKDKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 6e5s G 2.06 BS01 RET G 1 Y60 L77 W106 K108 L117 L119 Y60 L77 W106 K108 L117 L119 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKDKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 6e5s I 2.06 BS01 RET G 1 F16 I25 Q38 K40 D51 T53 S55 F16 I25 Q38 K40 D51 T53 S55 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKDKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 6e5s I 2.06 BS02 RET I 1 V62 L77 W106 K108 V62 L77 W106 K108 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKDKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 6e69 A 2.33 BS01 FUC A 1 W27 Q135 C201 N202 G207 W12 Q121 C179 N180 G181 3.4.21.37 P08246 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 6e69 A 2.33 BS02 HVP A 1 H57 C191 F192 S195 S214 F215 V216 C220 H41 C169 F170 S173 S188 F189 V190 C194 3.4.21.37 P08246 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 6e69 B 2.33 BS02 HVP B 1 H57 C191 F192 S195 S214 V216 H41 C169 F170 S173 S188 V190 3.4.21.37 P08246 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 6e69 C 2.33 BS02 HVP C 1 H57 S195 S214 V216 H41 S173 S188 V190 3.4.21.37 P08246 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 6e69 D 2.33 BS01 FUC D 1 W27 Q135 V200 N202 G207 W12 Q121 V175 N177 G178 3.4.21.37 P08246 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 6fje A 1.85 BS02 GLC A 1 W105 E303 E334 H343 W64 E262 E293 H302 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS03 GLC A 2 K151 Q226 P382 V383 E384 K110 Q185 P341 V342 E343 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS04 GLC A 3 E353 R355 D356 E361 E312 R314 D315 E320 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS05 NAG A 1 N52 T54 L55 N11 T13 L14 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS06 NAG A 2 N58 K405 L649 V650 W651 N17 K364 L608 V609 W610 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS07 NAG A 3 K405 W651 Y665 K364 W610 Y624 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS08 NAG A 4 N107 E128 K131 W134 N66 E87 K90 W93 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS09 NAG A 5 L279 P281 R355 N357 L238 P240 R314 N316 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS10 NAG A 6 F435 N444 G448 F394 N403 G407 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS11 NAG A 7 D117 S120 A466 A467 G470 N471 V635 D76 S79 A425 A426 G429 N430 V594 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS12 NAG A 8 M481 N483 S485 M440 N442 S444 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS13 NAG A 9 S430 N512 E566 S389 N471 E525 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS14 NAG A 10 E293 S537 N539 L559 K561 E252 S496 N498 L518 K520 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS15 NAG A 11 T545 K551 N555 T504 K510 N514 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS16 NAG A 12 T47 S524 E525 N606 T6 S483 E484 N565 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje A 1.85 BS17 NAG A 13 A59 T60 N644 S646 A18 T19 N603 S605 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje B 1.85 BS02 GLC B 1 W105 L170 E303 E334 H343 W64 L129 E262 E293 H302 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje B 1.85 BS03 GLC B 2 K151 Q226 W317 P382 V383 K110 Q185 W276 P341 V342 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje B 1.85 BS05 GLC B 4 T284 T285 E289 V363 I364 T243 T244 E248 V322 I323 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje B 1.85 BS09 NAG B 4 Y278 L279 P281 R355 N357 Y237 L238 P240 R314 N316 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje B 1.85 BS10 NAG B 5 P429 F435 N444 G448 P388 F394 N403 G407 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje B 1.85 BS11 NAG B 6 D117 S120 A467 G470 N471 V635 D76 S79 A426 G429 N430 V594 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6fje B 1.85 BS13 NAG B 8 E293 S537 N539 L559 E252 S496 N498 L518 J7HDY4 CSLDQTVAPGNLTLCGNATLFTTFRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDFNGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPETNLTGFRDPYVFQSPRLEALLANTTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTYLGPLVTTGYKESYGEWSGNYGINFETAGVTRLNPAGAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYASFPVEGYRQVSVGWIYEDDDNVILAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVPETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASEEEYTDIWFDPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTVFVDGSVIEIYANDEVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWDGLVDAWPARPANTSQGLVWDGPTAAMYGLFAGY 6h56 A 3.20 BS01 ZN A 1 H935 E936 H939 E983 H103 E104 H107 E151 Q9I6M7 SPASAVAGIAAAVGAAVAVGKLLGGPDAEAGRALSEGEISLAKGVFGDSIDYSTVRLRDEDYVPWQGKDYVMAPNGHIYFGEELRGVADWSLESLQRQGLFIHEMTHVWQHQHGVNVLLVGAYQQARQFLLGDQYAYRLEPGKTLKDYNIEQQGDIVRDYFLAANAFGEASANSRFAGVLK 6h56 B 3.20 BS01 ZN B 1 H935 H939 E983 H101 H105 E149 Q9I6M7 ASAVAGIAAAVGAAVAVGKLLGGPDAEAGRALSEGEISLAKGVFGDSIDYSTVRLRDEDYVPWQGKDYVMAPNGHIYFGEELRGVADWSLESLQRQGLFIHEMTHVWQHQHGVNVLLVGAYQQARQFLLGDQYAYRLEPGKTLKDYNIEQQGDIVRDYFLAANAFGEASANSRFAGVLK 6hpd A 2.43 BS01 MG A 1 N570 W571 I572 S590 E592 N543 W544 I545 S563 E565 3.2.1.23 T2KN75 31285597 EVITSSERTTYNFNVDWKFIKSNPKQAQDINYNDATWETISCPHTFNDVDTFDDLSHGHHDGEDNQWRGTVWYRKHFKLPKDDKGKKVFIEFESVRQIADVYINGVHLGQNQTGFIPFGFDLTPHLKFGEENIIAVKVNNDRGDHFRENFPLVWNHEHWHPTHGGIYRNVFLHTMDPLHITLPLYDNLETVGTYVYAENISEKSADITVETEIQNEHAENKNITLVTQIVDNDGAVVAHSNKNVAIPSGQKMKVTTVTNIQNPQLWYTRYPYMYKVVSAIKESNKVIDTYESPLGIRNFDFNKDSGFWINGEQIKLHGWGQKPTNAWAGLGAALPDWLRDFTFKLMDEAGGNFIRWGHCAASPAEVDMGDKYGFVTLMPGVSGESEDEGETWDIRYKAFKDLIVYYRNHPSIFIWEGGNWAESEAHYKEILEAIKTFDPKGKRLMGNRRADVKNDSEGYVSIEIGTEGWEREYPDLPIIESEYNREEAPRRIWDKNSPDDNFYNHPNISKNTYKLSSEEFAVRQADHWWNKMGKKAYHSGGANWIFSDGPHGGRCPTEVTRASGEVDAVRLPKEAFYALKAMWRPEPQVHIVGHWNYEVGTKKTMYVMSNCASVKLYVNDKLVGTNSNPENGYVFKFDNVAWESGKIKAEGFIDDALKTTQTKETTGEPAALKLTSITGPEGWLADGSDVALIDVEVVDAQGRRCPLAKGRVDFTISGPAIWRGGYNSGKPNSTNNLFLDIEAGINRVAVRSVLESGTVTIMAKKPGFKDVSVTLKSLPIDFNNGLTTTLPQVYTNVLTKEPLPEHIPEMPESELFRKFSYTGDGKAMLRTNMHWGKKAYTDLEYNYTVLPRYLNESEYVRTPNSDNRYWARDQLQFIAGKKMHIYVLHDDTVPRPEFLLRDYEDTGDNVNVVGASMSVFHRVAEEGESIIMAGNSDGDAPENCRMYTVMVKEFK 6hwo A 1.99 BS02 FFZ A 1 M273 L319 I336 M337 M357 S368 Q369 F372 I376 M191 L237 I254 M255 M275 S286 Q287 F290 I294 3.1.4.53 Q08499 GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQST 6hwo B 1.99 BS02 FFZ B 1 M273 L319 I336 M357 S368 Q369 G371 F372 M183 L229 I246 M267 S278 Q279 G281 F282 3.1.4.53 Q08499 VLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 6hwo C 1.99 BS02 FFZ C 1 H160 M273 L319 N321 I336 M337 M357 S368 Q369 F372 H74 M187 L233 N235 I250 M251 M271 S282 Q283 F286 3.1.4.53 Q08499 EQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 6hwo D 1.99 BS02 FFZ D 1 M273 L319 N321 I336 S368 Q369 G371 F372 M186 L232 N234 I249 S281 Q282 G284 F285 3.1.4.53 Q08499 QEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 6hz4 A 3.60 BS01 GNP A 1 D176 L177 F178 P203 G204 G206 K207 T208 F209 E280 F367 H407 S408 C411 D9 L10 F11 P36 G37 G39 K40 T41 F42 E113 F200 H240 S241 C244 3.1.21.- P15005 31296862 YCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz4 A 3.60 BS02 MG A 1 T208 D279 T41 D112 3.1.21.- P15005 31296862 YCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz4 A 3.60 BS03 GDP F 1 K301 R348 K134 R181 3.1.21.- P15005 31296862 YCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz4 B 3.60 BS01 GNP A 1 D300 K301 A345 R348 R349 D133 K134 A178 R181 R182 3.1.21.- P15005 31296862 YCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz4 B 3.60 BS02 GNP B 1 D176 L177 F178 P203 G204 G206 K207 T208 F209 E280 H407 S408 C411 C412 D9 L10 F11 P36 G37 G39 K40 T41 F42 E113 H240 S241 C244 C245 3.1.21.- P15005 31296862 YCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz4 C 3.60 BS01 GNP B 1 D300 K301 R348 R349 D133 K134 R181 R182 3.1.21.- P15005 31296862 YCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz4 C 3.60 BS02 GNP C 1 D176 L177 F178 P202 P203 G204 V205 G206 K207 T208 F209 F367 H407 S408 C411 C412 D9 L10 F11 P35 P36 G37 V38 G39 K40 T41 F42 F200 H240 S241 C244 C245 3.1.21.- P15005 31296862 YCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz4 E 3.60 BS01 GDP E 1 D176 F178 P203 G204 V205 G206 K207 F209 H407 S408 C411 C412 D4 F6 P31 G32 V33 G34 K35 F37 H235 S236 C239 C240 3.1.21.- P15005 31296862 ALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz4 F 3.60 BS01 GDP E 1 E298 D300 R348 E126 D128 R176 3.1.21.- P15005 31296862 ALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz4 F 3.60 BS02 GDP F 1 D176 F178 G206 K207 T208 F209 S408 C411 C412 D4 F6 G34 K35 T36 F37 S236 C239 C240 3.1.21.- P15005 31296862 ALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz5 D 4.20 BS01 GNP C 1 E298 D300 K301 R348 R349 E125 D127 K128 R175 R176 3.1.21.- P15005 31296862 LNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz5 E 4.20 BS01 GDP E 1 D176 L177 F178 G204 V205 G206 K207 F209 F367 H407 S408 C411 C412 D4 L5 F6 G32 V33 G34 K35 F37 F195 H235 S236 C239 C240 3.1.21.- P15005 31296862 ALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz5 F 4.20 BS02 GDP F 1 D176 F178 G204 G206 K207 T208 F209 H407 S408 C411 C412 D4 F6 G32 G34 K35 T36 F37 H235 S236 C239 C240 3.1.21.- P15005 31296862 ALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz5 J 4.20 BS01 GNP I 1 E298 D300 K301 A345 R348 R349 E125 D127 K128 A172 R175 R176 3.1.21.- P15005 31296862 LNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz6 E 4.30 BS01 GDP D 1 D300 K301 D128 K129 3.1.21.- P15005 31296862 ALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz6 F 4.30 BS01 GDP E 1 D300 R348 D128 R176 3.1.21.- P15005 31296862 ALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz6 F 4.30 BS02 GDP F 1 D176 F178 V205 G206 T208 F209 H407 S408 C411 C412 D4 F6 V33 G34 T36 F37 H235 S236 C239 C240 3.1.21.- P15005 31296862 ALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz8 E 4.30 BS01 GDP E 1 D176 L177 F178 G204 V205 G206 K207 T208 F209 S408 C411 C412 D4 L5 F6 G32 V33 G34 K35 T36 F37 S236 C239 C240 3.1.21.- P15005 31296862 ALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6hz9 A 4.80 BS01 GNP A 1 D176 F178 P203 G204 V205 G206 K207 T208 F209 E280 F367 H407 S408 C411 C412 D9 F11 P36 G37 V38 G39 K40 T41 F42 E113 F200 H240 S241 C244 C245 3.1.21.- P15005 31296862 YCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG 6ibo A 2.17 BS01 III C 1 H506 H508 H509 H568 P569 T643 K644 Q849 H182 H184 H185 H244 P245 T319 K320 Q507 2.4.1.255 O15294 31296563 THADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGKHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSIYDNRIVLNGIDLKAFLDSLPDVKIVKMLNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMI 6ibo A 2.17 BS02 12V A 1 H508 P569 T570 L663 G664 P666 F704 Q849 Y851 K852 L876 V905 A906 K908 H911 R914 C927 H930 T931 T932 D935 H184 P245 T246 L339 G340 P342 F380 Q507 Y509 K510 L534 V563 A564 K566 H569 R572 C585 H588 T589 T590 D593 2.4.1.255 O15294 31296563 THADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGKHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSIYDNRIVLNGIDLKAFLDSLPDVKIVKMLNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMI 6ilc A 2.20 BS01 III C 1 Y7 Y9 Y62 R65 N66 N69 A73 T76 Y77 G80 N83 V84 Y87 R100 Y102 T146 K149 W150 Y155 R158 Y162 W170 Y7 Y9 Y62 R65 N66 N69 A73 T76 Y77 G80 N83 V84 Y87 R100 Y102 T146 K149 W150 Y155 R158 Y162 W170 A0A125R585 31076531 GFHSLRYFYTAWSRPGSGEPRFVAVGYVDDTQFVRFDSDNASPRAEPRAPWMDLVEQQDPQYWDRNTRNARDAAQTYRVGLDNVRGYYNQSEAGSHTIQRMYGCDVGPHGRLLRGYDQLAYDGADYIALNEDLRSWTAADLAAQNTRRKWEEAGYAERDRAYLEGECVEWLLKHLENGRETLLRADPPKTHITHHPISDREVTLRCWALGFYPEEITLTWQHDGEDQTQEMELVETRPDGNGAFQKWAALVVPSGEEQRYTCHVQHEGLPQPLTLRWEP 6ile A 2.90 BS01 III C 1 Y7 Y9 Y59 N63 N66 A70 T73 Y74 G77 N80 V81 Y84 R97 Y99 L116 T143 K146 W147 Y152 Y159 W167 Y7 Y9 Y59 N63 N66 A70 T73 Y74 G77 N80 V81 Y84 R97 Y99 L116 T143 K146 W147 Y152 Y159 W167 A0A125R585 31076531 GFHSLRYFYTAWSRPGSGEPRFVAVGYVDDTQFVRFDSDNASPRAEPRAPWVEQQDPQYWDRNTRNARDAAQTYRVGLDNVRGYYNQSEAGSHTIQRMYGCDVGPHGRLLRGYDQLAYDGADYIALNEDLRSWTAADLAAQNTRRKWEEAGYAERDRAYLEGECVEWLLKHLENGRETLLRADPPKTHITHHPISDREVTLRCWALGFYPEEITLTWQHDGEDQTQEMELVETRPDGNGAFQKWAALVVPSGEEQRYTCHVQHEGLPQPLTLRWEP 6ilf A 2.70 BS01 III C 1 Y7 Y9 A24 V34 R35 F36 Y62 R65 N66 N69 A73 T76 V79 G80 N83 Y87 R100 Y102 T146 W150 A153 Y155 D159 Y162 W170 Y7 Y9 A24 V34 R35 F36 Y62 R65 N66 N69 A73 T76 V79 G80 N83 Y87 R100 Y102 T146 W150 A153 Y155 D159 Y162 W170 A0A125R585 31076531 GFHSLRYFYTAWSRPGSGEPRFVAVGYVDDTQFVRFDSDNASPRAEPRAPWMDLVEQQDPQYWDRNTRNARDAAQTYRVGLDNVRGYYNQSEAGSHTIQRMYGCDVGPHGRLLRGYDQLAYDGADYIALNEDLRSWTAADLAAQNTRRKWEEAGYAERDRAYLEGECVEWLLKHLENGRETLLRADPPKTHITHHPISDREVTLRCWALGFYPEEITLTWQHDGEDQTQEMELVETRPDGNGAFQKWAALVVPSGEEQRYTCHVQHEGLPQPLTLRWEP 6ilg A 2.60 BS01 III C 1 Y7 Y9 Y62 R65 N66 N69 A70 A73 T76 Y77 V79 N83 V84 Y87 R100 Y102 L119 Y126 T146 K149 W150 Y155 Y162 W170 Y7 Y9 Y62 R65 N66 N69 A70 A73 T76 Y77 V79 N83 V84 Y87 R100 Y102 L119 Y126 T146 K149 W150 Y155 Y162 W170 A0A125R585 31076531 GFHSLRYFYTAWSRPGSGEPRFVAVGYVDDTQFVRFDSDNASPRAEPRAPWMDLVEQQDPQYWDRNTRNARDAAQTYRVGLDNVRGYYNQSEAGSHTIQRMYGCDVGPHGRLLRGYDQLAYDGADYIALNEDLRSWTAADLAAQNTRRKWEEAGYAERDRAYLEGECVEWLLKHLENGRETLLRADPPKTHITHHPISDREVTLRCWALGFYPEEITLTWQHDGEDQTQEMELVETRPDGNGAFQKWAALVVPSGEEQRYTCHVQHEGLPQPLTLRWEP 6in7 A 1.96 BS01 NCA B 1 L56 L59 L57 L60 P38107 31297938 MMSREALQETLSAVMDNEADELELRRVLAACGEDAELRSTWSRYQLARSVMHREPTLPKLDIAAAVSAALADEAAPPKA 6in7 B 1.96 BS01 NCA B 1 A44 L113 E117 S118 R121 A40 L97 E101 S102 R105 Q06198 31297938 EQDQQLVERVQRGDKRAFDLLVLKYQHKILGLIVRFVHDAQEAQDVAQEAFIKAYRALGNFRGDSAFYTWLYRIAINTAKNHLVARGRRPFEGDHALKDIESPERAMLRDEIEATVHQTIQQLPEDLRTALTLREFEGLSYEDIATVMQCPVGTVRSRIFRAREAIDKALQPLL 6io9 A 1.90 BS01 SF4 A 1 A4 C24 G26 C27 Y30 V93 H95 C120 W123 A5 C25 G27 C28 Y31 V94 H96 C121 W124 I7F541 31101915 HMAGAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARIMMIGEQPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFKFTRAAGGKRRIHKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKALLGNDFRVTQHRGEVLHVDDVPGDPALVATVHPSSLLRGPKEERESAFAGLVDDLRVAADVR 6ioa A 2.15 BS01 SF4 A 1 A4 C24 G26 C27 K94 H95 C120 W123 A4 C24 G26 C27 K94 H95 C120 W123 I7F541 31101915 MAGAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARIMMIGEQPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFKFTRAAGGKRRIHKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKALLGNDFRVTQHRGEVLHVDDVPGDPALVATVHPSSLLRGPKEERESAFAGLVDDLRVAADV 6iob A 2.00 BS01 URA A 1 G51 E52 Q53 E58 P64 F65 N91 H178 G53 E54 Q55 E60 P66 F67 N93 H180 2.7.7.7 I7F541 31101915 SHMAGAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARIMMIGEQPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFKFTRAAGGKRRIAKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKALLGNDFRVTQHRGEVLHVDDVPGDPALVATVHPSSLLRGPKEERESAFAGLVDDLRVAADVR 6iob A 2.00 BS02 SF4 A 1 A4 C24 R25 G26 C27 Y30 H95 A119 C120 W123 A6 C26 R27 G28 C29 Y32 H97 A121 C122 W125 2.7.7.7 I7F541 31101915 SHMAGAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARIMMIGEQPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFKFTRAAGGKRRIAKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKALLGNDFRVTQHRGEVLHVDDVPGDPALVATVHPSSLLRGPKEERESAFAGLVDDLRVAADVR 6ioc A 1.62 BS01 SF4 A 1 A4 C24 G26 C27 Y30 V93 K94 H95 A119 C120 W123 A7 C27 G29 C30 Y33 V96 K97 H98 A122 C123 W126 2.7.7.7 I7F541 31101915 GSHMAGAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARIMMIGEQPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFKFTRAAGGKRRIQKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKALLGNDFRVTQHRGEVLHVDDVPGDPALVATVHPSSLLRGPKEERESAFAGLVDDLRVAADVRP 6ioc A 1.62 BS02 URA A 1 E52 Q53 E58 P64 F65 N91 Q109 H178 E55 Q56 E61 P67 F68 N94 Q112 H181 2.7.7.7 I7F541 31101915 GSHMAGAQDFVPHTADLAELAAAAGECRGCGLYRDATQAVFGAGGRSARIMMIGEQPGDKEDLAGLPFVGPAGRLLDRALEAADIDRDALYVTNAVKHFKFTRAAGGKRRIQKTPSRTEVVACRPWLIAEMTSVEPDVVVLLGATAAKALLGNDFRVTQHRGEVLHVDDVPGDPALVATVHPSSLLRGPKEERESAFAGLVDDLRVAADVRP 6iqq C 2.80 BS01 CA C 1 G408 I411 P412 D431 D433 Q435 G381 I384 P385 D404 D406 Q408 3.4.21.102 P23865 ITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLEGIGAVYQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFSAIASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKA 6isp D 1.88 BS01 CPQ D 1 T186 N196 P218 F220 T187 N197 P219 F221 3.1.1.3 P41365 ALPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSAQLGYTPCWISPPPFMLNDTQVNTEYMVNAITTLYAGSGNNKLPVLTVSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAGSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPYYAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIVT 6isp A 1.88 BS01 CPQ A 1 T186 V194 S195 N196 S197 L199 Q213 P218 F220 T188 V196 S197 N198 S199 L201 Q215 P220 F222 3.1.1.3 P41365 MALPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSAQLGYTPCWISPPPFMLNDTQVNTEYMVNAITTLYAGSGNNKLPVLTVSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAGSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPYYAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIV 6isp A 1.88 BS02 CPQ A 2 P143 Y282 P145 Y284 3.1.1.3 P41365 MALPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSAQLGYTPCWISPPPFMLNDTQVNTEYMVNAITTLYAGSGNNKLPVLTVSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAGSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPYYAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIV 6isp A 1.88 BS03 CPQ A 3 V139 L140 A185 T186 D187 E188 Q191 V194 V141 L142 A187 T188 D189 E190 Q193 V196 3.1.1.3 P41365 MALPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSAQLGYTPCWISPPPFMLNDTQVNTEYMVNAITTLYAGSGNNKLPVLTVSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAGSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPYYAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIV 6isp A 1.88 BS04 CPQ A 4 Q46 F71 A283 A284 A287 G288 Q48 F73 A285 A286 A289 G290 3.1.1.3 P41365 MALPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSAQLGYTPCWISPPPFMLNDTQVNTEYMVNAITTLYAGSGNNKLPVLTVSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAGSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPYYAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIV 6isp C 1.88 BS01 CPQ C 1 T186 V194 Q213 P218 F220 T188 V196 Q215 P220 F222 3.1.1.3 P41365 MALPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSAQLGYTPCWISPPPFMLNDTQVNTEYMVNAITTLYAGSGNNKLPVLTVSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAGSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPYYAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIVTP 6isp C 1.88 BS02 CPQ C 2 Q46 F71 A283 A287 Q48 F73 A285 A289 3.1.1.3 P41365 MALPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSAQLGYTPCWISPPPFMLNDTQVNTEYMVNAITTLYAGSGNNKLPVLTVSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAGSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPYYAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIVTP 6isp B 1.88 BS02 CPQ B 2 A185 T186 Q191 A186 T187 Q192 3.1.1.3 P41365 ALPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSAQLGYTPCWISPPPFMLNDTQVNTEYMVNAITTLYAGSGNNKLPVLTVSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAGSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPYYAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIVT 6itp A 1.57 BS01 HCY A 1 V24 T28 G29 S30 T31 G32 Y33 W34 T53 N77 K80 S101 T102 V24 T28 G29 S30 T31 G32 Y33 W34 T52 N76 K79 S100 T101 31049949 QVQLQESGGGSVQAGGSLRLSCVVSGNTGSTGYWAWFRQGPTEREGVAATYTAGSGTSMTYYADSVKGRFTISQDNAKKTLYLQMNSLKPEDTGMYRCASTRFAGRWYRDSEYRAWGQGTQVTVS 6itq A 1.53 BS01 HCY A 1 V24 T28 G29 S30 T31 G32 W34 T53 N77 S101 T102 V24 T28 G29 S30 T31 G32 W34 T50 N73 S97 T98 31049949 QVQLQESGGGSVQAGGSLRLSCVVSGNTGSTGYWAWFRQGPREGVAATYTAGSTSMTYYADSVKGRFTISQDNAKKTLYLQMNSLKPEDTGMYRCASTRFAGRWYRDSEYRAWGQGTQVTVS 6jbx A 2.20 BS01 NUC C 1 S33 K35 V60 T61 T64 D86 R87 R88 S36 K38 V63 T64 T67 D89 R90 R91 A0A062WM61 31291684 HHMDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVIGKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLIHRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK 6jbx A 2.20 BS02 NUC D 1 T50 P51 S52 L62 G63 T66 N70 R80 R88 V89 V90 T53 P54 S55 L65 G66 T69 N73 R83 R91 V92 V93 A0A062WM61 31291684 HHMDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVIGKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLIHRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK 6jmv A 1.83 BS01 SYM A 1 Y61 P88 T90 R95 V137 G140 A141 T142 N172 E189 Y215 Y61 P88 T90 R95 V137 G140 A141 T142 N172 E189 Y215 P42264 GSNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCP 6jut A 2.10 BS01 C9O A 1 C22 V30 A43 K45 A54 L57 S58 I66 F68 I80 T82 Y84 A85 G88 V140 C150 D151 F152 G153 F157 C15 V23 A36 K38 A47 L50 S51 I59 F61 I73 T75 Y77 A78 G81 V133 C143 D144 F145 G146 F150 2.7.11.25 Q9NYL2 31244114 FVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERDLSFK 6jwa A 1.78 BS01 5ID A 1 L45 V53 V66 I95 E114 H115 V116 M163 I174 L44 V52 V65 I94 E113 H114 V115 M162 I173 2.7.11.1 P68400 31282872 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 6k4k C 2.72 BS01 CA C 1 D21 D23 D25 T27 D19 D21 D23 T25 P0DP23 DQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRDKDGNGYISAAELRHVMTNLGEKGQVNYEEF 6k4k D 2.72 BS01 CA D 1 D21 D23 D25 T27 I28 D18 D20 D22 T24 I25 P0DP23 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAEEVDADGNGTIDFPEFLTMMARKMKDTDSEEEISAAELRHVMTNLGETDEE 6k4l C 2.95 BS01 CA C 1 D21 D23 T27 I28 D18 D20 T24 I25 P0DP23 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 6k4l D 2.95 BS01 CA D 1 D21 D23 G24 D25 G26 T27 I28 D18 D20 G21 D22 G23 T24 I25 P0DP23 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMEVDADGNGTIDFPEFLTMMARKMKDTDSEEEI 6k4r A 3.11 BS01 AMP A 1 R352 K367 T377 Y532 N534 R536 D542 D545 R254 K269 T279 Y418 N420 R422 D428 D431 Q5ZTK6 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 6k4r B 3.11 BS01 AMP B 1 R352 K367 T377 Q486 N534 R536 D542 D545 R253 K268 T278 Q387 N427 R429 D435 D438 Q5ZTK6 KQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFW 6k4r D 3.11 BS01 CA D 1 D21 D23 D25 T27 I28 T29 D19 D21 D23 T25 I26 T27 P0DP23 DQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMEVDADGNGTIDFPEFLTMMARKMKDTDSEEEI 6k5o A 1.80 BS02 D0O A 1 Y143 L223 V230 I267 S271 S274 W282 C284 Y291 H393 L400 L410 V414 Y21 L41 V48 I85 S89 S92 W100 C102 Y109 H211 L218 L228 V232 P13053 31300316 KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFG 6mii A 3.15 BS01 NUC X 1 T369 A371 V377 T354 A356 V362 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSEPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mii A 3.15 BS02 08T A 1 S302 I303 Y304 P342 G343 T344 A345 K346 S347 Q348 N448 I495 S287 I288 Y289 P327 G328 T329 A330 K331 S332 Q333 N433 I480 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSEPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mii A 3.15 BS03 ZN A 1 H144 C149 C171 C174 H138 C143 C165 C168 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSEPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mii A 3.15 BS04 ADP F 1 P559 R560 E563 P540 R541 E544 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSEPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mii B 3.15 BS01 NUC X 1 T369 A376 V377 Y386 K430 A431 T354 A361 V362 Y371 K415 A416 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mii B 3.15 BS02 08T A 1 E422 Q423 R473 P559 R560 E563 E407 Q408 R458 P544 R545 E548 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mii C 3.15 BS01 NUC X 1 T369 A376 V377 K430 A431 T354 A361 V362 K415 A416 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mii D 3.15 BS01 NUC X 1 T369 V377 K430 A431 T354 V362 K415 A416 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mii D 3.15 BS03 ADP D 1 S302 I303 Y304 G343 T344 A345 K346 S347 Q348 I495 S287 I288 Y289 G328 T329 A330 K331 S332 Q333 I480 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mii E 3.15 BS01 NUC X 1 T369 A371 A376 V377 K430 A431 T354 A356 A361 V362 K415 A416 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDMESG 6mii E 3.15 BS02 ADP D 1 E422 Q423 P559 R560 E563 E407 Q408 P544 R545 E548 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDMESG 6mii F 3.15 BS01 NUC X 1 K430 A431 K415 A416 3.6.4.12 Q9UXG1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM 6mnq H 1.80 BS01 III P 1 I31 I52 N58 R95 G97 I31 I52 N59 R99 G101 31263112 QVQLVQSGAEVKKPGASVKLSCKASGNTFSIYGISWVRQAPGQGLEWMGGIIPPAGLTNYVQRFQGRVTITADTSTTTVYMELSSLTSEDTAVYYCAIRIGRGFDYWGQGVLVTVSSASTKGPSVFPLAPTAALGCLVKDYFPEPVTVSWNSGSLTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYVCNVNHKPSNTKVDKRVEIK 6mnq L 1.80 BS01 III P 1 Y32 T91 I92 E93 Y94 F96 Y38 T97 I98 E99 Y100 F102 31263112 DIVMTQSPLSLPVTPGETASISCRSSQSLLDSEDGNTYLEWYLQKPGQSPQALIYEASNRASGVPDRFSGSGSDTDFTLKISRVEAEDVGIYYCMQTIEYPFTFGPGTKVDIKRAVAAPSVFIFPPSEDQVKSGTVSVVCLLNNFYPREASVKWKVDGVLKTGNSQESVTEQDSKDNTYSLSSTLTLSNTDYQSHNVYACEVTHQGLSSPVTKSFNRGE 6mnr H 2.20 BS01 III P 1 W33 S35 W47 F50 D53 V97 H100 Y100B E101 W33 S35 W47 F50 D56 V103 H106 Y108 E110 31263112 EVHLVESGGGLVQPGGSLRLSCEVSGLTFSNSWMSWVRQAPGKGLEWVGFIKTKADGGTAAYAESVKGRFTISRDDSKNTVFLQMKSLKTEDTAVYYCQGAVVISHEYIEIWGQGALVTVSSASTKGPSVFPLAPSSESTAALGCLVKDYFPEPVTVSWNSGSLTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYVCNVNHKPSNTKVDKRVEIK 6mnr L 2.20 BS01 III P 1 Y36 Y50 R53 W91 Y96 Y36 Y50 R53 W91 Y98 31263112 SVLTQPPSASEAARKSVTISCSGGSSNIGDDSVSWYQQVPGTAPKLLIYYNDRRASGVSDRFSGSKSGTSASLAINGLQSEDEADYYCAAWDDSLSAYIFGSGTRLTVLGQPKASPTVTLFPPSSEELQANKATLVCLISDFYPGVVKVAWKADGSAVNAGVETTTPSKQSNNKYAASSYLSLTSDQWKSHKSYSCQVTHEGSTVEKTVAP 6mns H 2.70 BS01 III P 1 W33 S35 W47 F50 V97 H100 Y100B E101 W33 S35 W47 F50 V103 H106 Y108 E110 31263112 EVHLVESGGGLVQPGGSLRLSCEVSGLTFSNSWMSWVRQAPGKGLEWVGFIKTKADGGTAAYAESVKGRFTISRDDSKNTVFLQMKSLKTEDTAVYYCQGAVVISHEYIEIWGQGALVTVSSASTKGPSVFPLAPSSRSTSESTAALGCLVKDYFPEPVTVSWNSGSLTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYVCNVNHKPSNTKVDKRVEI 6mns A 2.70 BS01 III Q 1 W33 S35 W47 F50 V97 Y100B E101 W33 S35 W47 F50 V103 Y108 E110 31263112 EVHLVESGGGLVQPGGSLRLSCEVSGLTFSNSWMSWVRQAPGKGLEWVGFIKTKADGGTAAYAESVKGRFTISRDDSKNTVFLQMKSLKTEDTAVYYCQGAVVISHEYIEIWGQGALVTVSSASTKGPSVFPLAPSSRSTSESTAALGCLVKDYFPEPVTVSWNSGSLTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYVCNVNHKPSNTKVDKRVEIK 6mns B 2.70 BS01 III Q 1 D31 Y36 Y50 R53 W91 Y96 D31 Y36 Y50 R53 W91 Y98 31263112 SVLTQPPSASEAARKSVTISCSGGSSNIGDDSVSWYQQVPGTAPKLLIYYNDRRASGVSDRFSGSKSGTSASLAINGLQSEDEADYYCAAWDDSLSAYIFGSGTRLTVLGQPKASPTVTLFPPSSEELQANKATLVCLISDFYPGVVKVAWKADGSAVNAGVETTTPSKQSNNKYAASSYLSLTSDQWKSHKSYSCQVTHEGSTVEKTVAP 6muo A 3.60 BS01 NUC I 1 R72 N85 W86 Q87 R118 V119 T120 R32 N45 W46 Q47 R78 V79 T80 P49450 SRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6muo A 3.60 BS02 NUC J 1 R42 G46 R63 K64 L65 P66 R2 G6 R23 K24 L25 P26 P49450 SRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6muo A 3.60 BS03 III L 1 Q127 R130 R131 L135 L139 Q87 R90 R91 L95 L99 P49450 SRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6muo B 3.60 BS03 III L 1 E53 G56 E46 G49 P62805 KGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6muo C 3.60 BS02 NUC J 1 S16 R29 R42 V43 G44 A45 K75 T76 R77 S3 R16 R29 V30 G31 A32 K62 T63 R64 Q93077 AKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQSVLL 6muo C 3.60 BS03 III L 1 E61 D90 E91 E92 L93 E48 D77 E78 E79 L80 Q93077 AKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQSVLL 6muo D 3.60 BS02 NUC J 1 R33 E35 S36 V39 Y40 R1 E3 S4 V7 Y8 Q5QNW6 RKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSS 6muo D 3.60 BS03 III L 1 L106 H109 L74 H77 Q5QNW6 RKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSS 6muo E 3.60 BS01 NUC I 1 R43 G46 R63 K64 L65 P66 R69 R3 G6 R23 K24 L25 P26 R29 P49450 SRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6muo F 3.60 BS02 NUC J 1 K31 P32 R36 K44 R45 K10 P11 R15 K23 R24 P62805 LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6muo G 3.60 BS02 NUC J 1 K15 S16 R17 R20 G28 R29 R32 R42 R77 K3 S4 R5 R8 G16 R17 R20 R30 R65 Q93077 KAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQSVLLP 6muo G 3.60 BS03 III K 1 E56 E61 N89 D90 E91 E44 E49 N77 D78 E79 Q93077 KAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQSVLLP 6muo M 3.60 BS01 NUC I 1 P17 M18 R44 K45 L168 R169 R170 P17 M18 R44 K45 L161 R162 R163 Q96H22 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQT 6muo M 3.60 BS02 NUC J 1 K81 S165 M167 R194 K81 S158 M160 R187 Q96H22 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQT 6mup A 3.50 BS01 NUC I 1 R72 N85 W86 Q87 R118 V119 T120 F122 R35 N48 W49 Q50 R81 V82 T83 F85 P49450 HQHSRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6mup A 3.50 BS02 NUC J 1 R43 R44 R63 K64 L65 P66 R69 N85 R6 R7 R26 K27 L28 P29 R32 N48 P49450 HQHSRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6mup A 3.50 BS03 III L 1 Q127 R130 R131 G138 L139 Q90 R93 R94 G101 L102 P49450 HQHSRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6mup C 3.50 BS03 III L 1 E56 E64 D90 E91 E92 E43 E51 D77 E78 E79 Q93077 AKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQSVLL 6mup D 3.50 BS02 NUC J 1 K34 E35 Y40 K43 K2 E3 Y8 K11 Q5QNW6 RKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSS 6mup E 3.50 BS01 NUC I 1 R43 G46 W47 R63 K64 L65 P66 R69 N85 R5 G8 W9 R25 K26 L27 P28 R31 N47 P49450 QHSRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6mup E 3.50 BS02 NUC J 1 R72 N85 W86 Q87 V119 T120 R34 N47 W48 Q49 V81 T82 P49450 QHSRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6mup E 3.50 BS03 III K 1 Q127 R130 R131 L135 G138 Q89 R92 R93 L97 G100 P49450 QHSRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGL 6mup F 3.50 BS03 III K 1 E52 E53 G56 E41 E42 G45 P62805 KGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6mup G 3.50 BS02 NUC J 1 A14 K15 S16 R17 G28 R32 R42 R77 A2 K3 S4 R5 G16 R20 R30 R65 Q93077 KAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQSVLLP 6mup G 3.50 BS03 III K 1 E61 E64 L65 N89 D90 E91 E92 L93 E49 E52 L53 N77 D78 E79 E80 L81 Q93077 KAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQSVLLP 6mup M 3.50 BS01 NUC I 1 M18 K45 M167 R169 M18 K45 M160 R162 Q96H22 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQT 6mup M 3.50 BS02 NUC J 1 R42 K81 V82 S165 M167 R194 R42 K81 V82 S158 M160 R187 Q96H22 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQT 6mup N 3.50 BS01 NUC I 1 R42 R44 K81 K148 M167 R194 R42 R44 K81 K141 M160 R187 Q96H22 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQT 6mup N 3.50 BS02 NUC J 1 P17 M18 R44 K45 R169 R170 P17 M18 R44 K45 R162 R163 Q96H22 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQT 6mxb A 2.19 BS01 XMP A 1 E147 I149 D151 T152 G153 T155 K180 R200 Y201 V202 F207 E208 E129 I131 D133 T134 G135 T137 K162 R182 Y183 V184 F189 E190 Q38CA1 31287615 PLKPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 6mxb A 2.19 BS02 MG A 1 Y213 Y230 Y195 Y212 Q38CA1 31287615 PLKPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 6mxb B 2.19 BS01 XMP B 1 E147 I149 D151 T152 G153 R154 T155 K180 Y201 V202 F207 E208 E127 I129 D131 T132 G133 R134 T135 K160 Y181 V182 F187 E188 Q38CA1 31287615 KPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRIQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 6mxb D 2.19 BS02 MG D 1 V85 G88 E147 D148 V77 G80 E126 D127 Q38CA1 31287615 PNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRIQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSK 6mxb E 2.19 BS01 XMP E 1 E147 D148 I149 D151 T152 G153 R154 T155 K180 Y201 V202 F207 E208 E123 D124 I125 D127 T128 G129 R130 T131 K156 Y177 V178 F183 E184 Q38CA1 31287615 PNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRIDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 6mxc C 1.99 BS01 5GP C 1 D148 I149 A150 D151 T152 G153 R154 T155 K180 R200 Y201 V202 F207 E208 D134 I135 A136 D137 T138 G139 R140 T141 K166 R186 Y187 V188 F193 E194 Q38CA1 31287615 KPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYGTVQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 6mxc F 1.99 BS02 MG F 1 L86 K87 G88 L79 K80 G81 Q38CA1 31287615 KPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSTVQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 6mxd A 2.96 BS02 MG A 1 K87 G88 R214 K82 G83 R197 Q38CA1 31287615 PLKPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 6mxd B 2.96 BS02 MG B 1 K87 R214 K82 R196 Q38CA1 31287615 PLKPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 6mxd D 2.96 BS01 IMP D 1 I149 D151 T152 G153 T155 K180 R200 Y201 V202 F207 I132 D134 T135 G136 T138 K163 R183 Y184 V185 F190 Q38CA1 31287615 PLKPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 6mxg A 2.39 BS01 XMP A 1 E113 I115 D117 T118 A119 L120 T121 L122 K145 F166 V167 L172 D173 E87 I89 D91 T92 A93 L94 T95 L96 K119 F140 V141 L146 D147 2.4.2.8 Q07010 31287615 ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFTADMVRILGDFGVPTRVEFLRIRGKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVYETWGK 6mxg B 2.39 BS01 XMP B 1 D117 T118 K145 F166 V167 V168 L172 D173 D89 T90 K117 F138 V139 V140 L144 D145 2.4.2.8 Q07010 31287615 CKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFTADMVRILGDFGVPTRVEFLRRGKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVYETWGKELE 6mxg B 2.39 BS02 MG B 1 L53 E113 D114 I115 L49 E85 D86 I87 2.4.2.8 Q07010 31287615 CKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFTADMVRILGDFGVPTRVEFLRRGKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVYETWGKELE 6n5u A 2.66 BS01 CU1 A 1 F39 C42 C46 H131 F32 C35 C39 H124 Q8VYP0 AIGGPFSLIRDDGKRVTEKNLMGKWTILYFGFTHCPDICPDELIKLAAAIDKIKENSGVDVVPVFISVDPERDTVQQVHEYVKEFHPKLIGLTGSPEEIKSVARSYRVYYMKTEEEDSDYLVDHSIVMYLMSPEMNFVKFYGKNHDVDSLTDGVVKEIRQY 6n5u B 2.66 BS01 CU1 B 1 C42 C46 H131 C35 C39 H120 Q8VYP0 AIGGPFSLIRDDGKRVTEKNLMGKWTILYFGFTHCPDICPDELIKLAAAIDKIKENSGVDVVPVFISVDPERDTVQQVHEYVKEFHPKLIGLTGSPEEIKSVARSYRVYYMKTEDYLVDHSIVMYLMSPEMNFVKFYGKNHDVDSLTDGVVKEIRQY 6n8e A 3.00 BS01 PNS A 1 A18 I21 L25 Y32 H144 A296 V298 E334 R337 R338 I343 S1016 A15 I18 L22 Y29 H137 A289 V291 E327 R330 R331 I336 S995 LNPADVLPLTAAQNAIWIGHQLDPASAAYNVAAHVGVDAALDADLLRRAFDITANETDCLRMRFVETGSAVRQTFVARAETAFVMRDFRAEPDSTGAAHAWMAADVRRRIDLSSGCLVHAALLRTGTRDYVYLRSHHIALDGFGLAMVLRRVAHVYGALVAGREPAAAAFGAFAEVIDADRAYHASAACEADRAYWRAYCAGLDDVPTLCAGTSLPSEIAVCHTAPVPAALVERLHDFANECGTHWINVVVAAFGAFVGRATSRRDITIGVPMMNRLGGVAASVPCTTANVLPLSLDVRPGARAEALVEAVDTGLAGMRRHQRYRAEDIRRDCHLIGEGRRLTGPQINVDVYTDPIAFGDASGIARVVSAGPADDVSLMIQRGDMADALTIVGMANPALYRPHELARWIERFVAFTTAFVADPSCPVGRLDAYLPGDGVEVHLPEPAKRSLGATLVEVFERRVAERPHASAVTLDHTTWDYAELDARANRLARHFAASTPARGNLRVALLLPRTLDAIVAILATLKFGAAYVPIDPDAPAERIRAIIDDCDAALVVTTVDLASRIDASGRRLVVLDAPDTRAAVAAASAAPPSRDGEGPRADDLAYIIFTSKPKGVKITHRNVVRLFEATDAWFHYRDDDVWTMCHAYVFDASVWEMWGALLHGGRLVVVPPETTRAPDALLELVVREGVTVFGQIPSAFYRFMEAQADHPALRQALRLRYQCFGGEALDPSRLKPWFDWHRDSGTRLLNMYGITETTINATYRFIDERDVDTGRGSLIGEVYADLGIVVLDDALRPVPAGAYGEMYVTGAGLAQGYLNRPDLDAVRFVANPYGPAGTRMYRSGDVARLHPDGVLEYVGRADQQVKVRGYRIELGEVEARLREYAPVSDAVVSVRRDAVGDVQLVAHVVARRVEALRAHLRERVPAYMVPAAFGTLDALPMTRNGKVDRKALPDISVVEPPRDALDERIVELWREQCGDVAIGIDDNFFDVGGDSIKAIRVARALDMPVMALFDAPTVRACADYLRDALDRTLHHFKRPAQARVHMVCVPFAGGSALSYRELARALPDGFACSALQLPGHDPAAPDEAFVDLDTTIDRAVDRLLAEAAAPIVVYGHCAGNALAVALVRRLAGAGANVIGLAIGGMLLDEDADAVLDEVGARSGENIVDFLRQIGGFKDVLDAGTLAAIARMTKHDAMQAATFFAAETRAPARLDVPLHVVIGGQDPLTPDYARRYLDWRRYSDAVELDVIPDGGHYFVTEHADTLAGLLAARWLRQALRAFLNPFDDEDEVHYLLANDLGAHSLWPAFVPLPGGWRVVAGPASRDACLGALP 6n8e A 3.00 BS02 KFG A 1 G821 L824 G848 T849 R850 G810 L813 G837 T838 R839 LNPADVLPLTAAQNAIWIGHQLDPASAAYNVAAHVGVDAALDADLLRRAFDITANETDCLRMRFVETGSAVRQTFVARAETAFVMRDFRAEPDSTGAAHAWMAADVRRRIDLSSGCLVHAALLRTGTRDYVYLRSHHIALDGFGLAMVLRRVAHVYGALVAGREPAAAAFGAFAEVIDADRAYHASAACEADRAYWRAYCAGLDDVPTLCAGTSLPSEIAVCHTAPVPAALVERLHDFANECGTHWINVVVAAFGAFVGRATSRRDITIGVPMMNRLGGVAASVPCTTANVLPLSLDVRPGARAEALVEAVDTGLAGMRRHQRYRAEDIRRDCHLIGEGRRLTGPQINVDVYTDPIAFGDASGIARVVSAGPADDVSLMIQRGDMADALTIVGMANPALYRPHELARWIERFVAFTTAFVADPSCPVGRLDAYLPGDGVEVHLPEPAKRSLGATLVEVFERRVAERPHASAVTLDHTTWDYAELDARANRLARHFAASTPARGNLRVALLLPRTLDAIVAILATLKFGAAYVPIDPDAPAERIRAIIDDCDAALVVTTVDLASRIDASGRRLVVLDAPDTRAAVAAASAAPPSRDGEGPRADDLAYIIFTSKPKGVKITHRNVVRLFEATDAWFHYRDDDVWTMCHAYVFDASVWEMWGALLHGGRLVVVPPETTRAPDALLELVVREGVTVFGQIPSAFYRFMEAQADHPALRQALRLRYQCFGGEALDPSRLKPWFDWHRDSGTRLLNMYGITETTINATYRFIDERDVDTGRGSLIGEVYADLGIVVLDDALRPVPAGAYGEMYVTGAGLAQGYLNRPDLDAVRFVANPYGPAGTRMYRSGDVARLHPDGVLEYVGRADQQVKVRGYRIELGEVEARLREYAPVSDAVVSVRRDAVGDVQLVAHVVARRVEALRAHLRERVPAYMVPAAFGTLDALPMTRNGKVDRKALPDISVVEPPRDALDERIVELWREQCGDVAIGIDDNFFDVGGDSIKAIRVARALDMPVMALFDAPTVRACADYLRDALDRTLHHFKRPAQARVHMVCVPFAGGSALSYRELARALPDGFACSALQLPGHDPAAPDEAFVDLDTTIDRAVDRLLAEAAAPIVVYGHCAGNALAVALVRRLAGAGANVIGLAIGGMLLDEDADAVLDEVGARSGENIVDFLRQIGGFKDVLDAGTLAAIARMTKHDAMQAATFFAAETRAPARLDVPLHVVIGGQDPLTPDYARRYLDWRRYSDAVELDVIPDGGHYFVTEHADTLAGLLAARWLRQALRAFLNPFDDEDEVHYLLANDLGAHSLWPAFVPLPGGWRVVAGPASRDACLGALP 6n8e A 3.00 BS03 KFJ A 1 F661 D662 A663 Q706 G736 G737 G764 I765 T766 I770 N771 F650 D651 A652 Q695 G725 G726 G753 I754 T755 I759 N760 LNPADVLPLTAAQNAIWIGHQLDPASAAYNVAAHVGVDAALDADLLRRAFDITANETDCLRMRFVETGSAVRQTFVARAETAFVMRDFRAEPDSTGAAHAWMAADVRRRIDLSSGCLVHAALLRTGTRDYVYLRSHHIALDGFGLAMVLRRVAHVYGALVAGREPAAAAFGAFAEVIDADRAYHASAACEADRAYWRAYCAGLDDVPTLCAGTSLPSEIAVCHTAPVPAALVERLHDFANECGTHWINVVVAAFGAFVGRATSRRDITIGVPMMNRLGGVAASVPCTTANVLPLSLDVRPGARAEALVEAVDTGLAGMRRHQRYRAEDIRRDCHLIGEGRRLTGPQINVDVYTDPIAFGDASGIARVVSAGPADDVSLMIQRGDMADALTIVGMANPALYRPHELARWIERFVAFTTAFVADPSCPVGRLDAYLPGDGVEVHLPEPAKRSLGATLVEVFERRVAERPHASAVTLDHTTWDYAELDARANRLARHFAASTPARGNLRVALLLPRTLDAIVAILATLKFGAAYVPIDPDAPAERIRAIIDDCDAALVVTTVDLASRIDASGRRLVVLDAPDTRAAVAAASAAPPSRDGEGPRADDLAYIIFTSKPKGVKITHRNVVRLFEATDAWFHYRDDDVWTMCHAYVFDASVWEMWGALLHGGRLVVVPPETTRAPDALLELVVREGVTVFGQIPSAFYRFMEAQADHPALRQALRLRYQCFGGEALDPSRLKPWFDWHRDSGTRLLNMYGITETTINATYRFIDERDVDTGRGSLIGEVYADLGIVVLDDALRPVPAGAYGEMYVTGAGLAQGYLNRPDLDAVRFVANPYGPAGTRMYRSGDVARLHPDGVLEYVGRADQQVKVRGYRIELGEVEARLREYAPVSDAVVSVRRDAVGDVQLVAHVVARRVEALRAHLRERVPAYMVPAAFGTLDALPMTRNGKVDRKALPDISVVEPPRDALDERIVELWREQCGDVAIGIDDNFFDVGGDSIKAIRVARALDMPVMALFDAPTVRACADYLRDALDRTLHHFKRPAQARVHMVCVPFAGGSALSYRELARALPDGFACSALQLPGHDPAAPDEAFVDLDTTIDRAVDRLLAEAAAPIVVYGHCAGNALAVALVRRLAGAGANVIGLAIGGMLLDEDADAVLDEVGARSGENIVDFLRQIGGFKDVLDAGTLAAIARMTKHDAMQAATFFAAETRAPARLDVPLHVVIGGQDPLTPDYARRYLDWRRYSDAVELDVIPDGGHYFVTEHADTLAGLLAARWLRQALRAFLNPFDDEDEVHYLLANDLGAHSLWPAFVPLPGGWRVVAGPASRDACLGALP 6nj7 A 2.60 BS01 NAP A 1 G41 S43 K44 G45 I46 A65 R66 S67 T92 M93 N119 H120 I121 V168 S169 Y183 K187 L215 G216 L217 I218 T220 T222 A223 G8 S10 K11 G12 I13 A32 R33 S34 T59 M60 N86 H87 I88 V135 S136 Y150 K154 L182 G183 L184 I185 T187 T189 A190 1.1.1.146 P28845 31294974 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYS 6nj7 A 2.60 BS02 7H6 A 1 L126 S170 V180 Y183 L217 L93 S137 V147 Y150 L184 1.1.1.146 P28845 31294974 GKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYS 6nj7 B 2.60 BS01 NAP B 1 G41 S43 K44 G45 I46 A65 R66 S67 T92 M93 N119 H120 I121 N123 V168 S169 S170 Y183 K187 L215 G216 L217 I218 T220 T222 A223 G16 S18 K19 G20 I21 A40 R41 S42 T67 M68 N94 H95 I96 N98 V143 S144 S145 Y158 K162 L190 G191 L192 I193 T195 T197 A198 1.1.1.146 P28845 31294974 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYST 6nj7 B 2.60 BS02 7H6 B 1 S170 V180 Y183 L217 S145 V155 Y158 L192 1.1.1.146 P28845 31294974 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYST 6nj7 C 2.60 BS01 NAP C 1 G41 S43 K44 G45 I46 R66 S67 T92 M93 N119 I121 V168 S169 S170 Y183 K187 L215 G216 L217 I218 T220 T222 A223 G16 S18 K19 G20 I21 R41 S42 T67 M68 N94 I96 V143 S144 S145 Y158 K162 L190 G191 L192 I193 T195 T197 A198 1.1.1.146 P28845 31294974 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLY 6nj7 C 2.60 BS02 7H6 C 1 T124 L126 S170 V180 Y183 L217 T99 L101 S145 V155 Y158 L192 1.1.1.146 P28845 31294974 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLY 6nj7 D 2.60 BS01 NAP D 1 G41 A42 S43 K44 G45 I46 A65 R66 T92 M93 N119 I121 V168 S169 S170 Y183 K187 L215 G216 I218 T220 T222 A223 G14 A15 S16 K17 G18 I19 A38 R39 T62 M63 N89 I91 V138 S139 S140 Y153 K157 L185 G186 I188 T190 T192 A193 1.1.1.146 P28845 31294974 RPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARTLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYST 6nj7 D 2.60 BS02 7H6 D 1 T124 S170 V180 Y183 L217 A223 T94 S140 V150 Y153 L187 A193 1.1.1.146 P28845 31294974 RPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARTLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYST 6no7 E 3.55 BS02 ATP E 1 G50 T51 G52 S53 F54 V57 K72 E127 D166 K168 L173 T183 D184 F327 G39 T40 G41 S42 F43 V46 K61 E116 D155 K157 L162 T172 D173 F316 2.7.11.11 P17612 QESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 6no7 G 3.55 BS01 MG G 1 E170 N171 E157 N158 2.7.11.11 P17612 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 6no7 G 3.55 BS03 ATP G 1 G52 V57 A70 K72 M120 E121 Y122 V123 E127 D166 K168 N171 L173 T183 D184 G39 V44 A57 K59 M107 E108 Y109 V110 E114 D153 K155 N158 L160 T170 D171 2.7.11.11 P17612 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 6np0 A 2.92 BS01 CWB A 1 N101 S155 W156 F199 I201 Y207 N95 S149 W150 F193 I195 Y201 E9QLC0 TTQPALLRLSDHLLANYKKGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQRPVPDWLRHLVLDRIAWILCLLAVRGLLQELSSIRHFLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 6np0 A 2.92 BS02 CWB B 1 D42 V43 I44 W63 R65 Y126 R169 D36 V37 I38 W57 R59 Y120 R163 E9QLC0 TTQPALLRLSDHLLANYKKGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQRPVPDWLRHLVLDRIAWILCLLAVRGLLQELSSIRHFLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 6np0 B 2.92 BS01 CWB B 1 N101 T154 S155 W156 F199 I201 Y207 N95 T148 S149 W150 F193 I195 Y201 E9QLC0 TTQPALLRLSDHLLANYKKGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQRPVPDWLRHLVLDRIAWILCLLAVRGLLQELSSIRHFLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 6np0 B 2.92 BS02 CWB C 1 D42 I44 R65 Y126 R169 D36 I38 R59 Y120 R163 E9QLC0 TTQPALLRLSDHLLANYKKGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQRPVPDWLRHLVLDRIAWILCLLAVRGLLQELSSIRHFLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 6np0 C 2.92 BS02 CWB D 1 D42 I44 W63 R65 Y126 R169 D36 I38 W57 R59 Y120 R163 E9QLC0 TTQPALLRLSDHLLANYKKGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQRPVPDWLRHLVLDRIAWILCLLAVRGLLQELSSIRHFLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 6nw4 A 3.00 BS01 6NT A 1 A51 R53 A81 W110 E178 C180 W210 A50 R52 A80 W109 E177 C179 W209 4.1.1.48 Q06121 31282667 PRYLKGWLKDVVQLSLRRPSFRASRQRPIISLNERILEFNKRNITAIIAAYRRKSPCGLDVERDPIEYSKFMERYAVGLAIATEEKYFNGSYETLRKIASSVSIPILMWDFIVKESQIDDAYNLGADTVALIVKILTERELESLLEYARSYGMEPYIVINDENDLDIALRIGARFIEICSRDFETLEINKENQRKLISMIPSNVVKVAWGGISERNEIEELRKLGVNAFGIGSSLMRNPEKIKEFIL 6nze A 1.96 BS01 L8Y A 1 L595 V603 V640 K642 A671 T687 E688 Y689 V690 E691 G693 R738 N739 L741 S758 D759 L15 V23 V33 K35 A64 T80 E81 Y82 V83 E84 G86 R131 N132 L134 S151 D152 2.7.10.2 P29597 31314518 FHRVDQKEITQLSHLGQGTRTNVYEGRLRLRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 6nzh A 2.73 BS01 L9A A 1 L595 G596 V603 V640 K642 T687 E688 Y689 V690 E691 H692 G693 P694 R738 N739 L741 S758 D759 L15 G16 V23 V32 K34 T79 E80 Y81 V82 E83 H84 G85 P86 R130 N131 L133 S150 D151 2.7.10.2 P29597 31314518 FHRVDQKEITQLSHLGQGTRTNVYEGRLLRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPSTAMDKWGFGATLLEICFDGEAPLSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 6o38 A 2.60 BS01 ZN A 1 H498 H502 H508 H490 H494 H500 ATVLSPNQNNNSGSIPTGYSDLEFSLANGNWVKNLSLPTNANNSDKITIRSSAAYSSYLDTSNTNIPLEVLKINSGDVYQFIFNSSQNKWIAQLATVSPTTGSNYELIPLTTATQKVLIQDDKWAQTIALPSDVRDGTTVQVVSTASVSSDIDKTNLLFPSSFTLKNGSEYWFKYYSALGKWVPEYIKPQKLNVQQIGTSLAAVNSPLTEIAFGDGNWVSNFTLPTTANDRDRIIIKSTATWSAKINNTNVNSQATLTLKTGDQYEFYVSDKGYWQLISSPTKVIDSTATIPAILPNTQPTLKVKLSTSNWQPTLQLPAQAQVGDKVVIVSNASADTYINAANGLSTAIKNGENRRFIYTAQGWTVDSYTIDLLVSSPEVNSILGESAAKLRIEGVNLTNLTAENSNARFYLRDVGYITYKIPAATLKEAISTGRDDTTVQNERKRILADGVYYQGNEPGDGGCGWAWINASAYNIGANDIAGCSFAARHEVGHNLGLYHNGSTNIGSGFAHPLGSTAGGNNINFYSSPYLYNPKYGVRLGEEGKIDAVSVINLNAQKISLYNHH 6o4b A 1.85 BS01 NAD A 1 I163 T164 A165 F166 N167 K190 A192 P193 A227 G230 T231 F244 T245 G246 S247 V250 V254 E268 L269 G270 C302 E399 F401 F468 I161 T162 A163 F164 N165 K188 A190 P191 A225 G228 T229 F242 T243 G244 S245 V248 V252 E266 L267 G268 C300 E397 F399 F466 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31302938 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGGNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 6o4d A 1.88 BS01 6PC A 1 E121 F168 R301 T303 G461 A462 F468 E119 F166 R299 T301 G459 A460 F466 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31302938 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGANNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKF 6o4d C 1.88 BS01 6PC C 1 E121 F168 V172 R301 T303 G461 A462 F468 E119 F166 V170 R299 T301 G459 A460 F466 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31302938 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGANNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKF 6o4h D 2.05 BS01 NAD D 1 I163 T164 A165 F166 N167 K190 G191 A192 P193 G230 T231 F244 T245 G246 S247 V250 V254 E268 L269 G270 C302 E399 F401 F468 I161 T162 A163 F164 N165 K188 G189 A190 P191 G228 T229 F242 T243 G244 S245 V248 V252 E266 L267 G268 C300 E397 F399 F466 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31302938 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVVVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYS 6o5f A 2.50 BS01 NUC C 1 S181 S183 T201 R202 E449 T450 K451 H472 G473 R480 T498 A499 V500 H578 H579 S38 S40 T58 R59 E290 T291 K292 H313 G314 R321 T339 A340 V341 H415 H416 3.6.4.13 O00571 31300642 DDWSKPLPPSERLEQELFKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARSNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHY 6o5f A 2.50 BS02 NUC D 1 E180 S520 D521 N551 E37 S357 D358 N388 3.6.4.13 O00571 31300642 DDWSKPLPPSERLEQELFKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARSNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHY 6o5f B 2.50 BS01 NUC C 1 E180 R199 S520 D521 N551 E37 R56 S357 D358 N388 3.6.4.13 O00571 31300642 DDWSKPLPPSERLEQELFKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARSNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHY 6oh9 A 1.75 BS01 ZN A 1 H100 H102 H258 D348 H81 H83 H239 D329 3.5.4.3 Q07729 31283204 DKHGKFLVFFGTFVDTPKLGELRIREKTSVGVLNGIIRFVNRNSLDPVKDCLDHDSSLSPEDVTVVDINNSFYFPGFVDTHNHVSQYPNVGVFGNSTLLDWLEKYTFPIEAALANENIAREVYNKVISKTLSHGTTTVAYYNTIDLKSTKLLAQLSSLLGQRVLVGKVCMDTNGPEYYIEDTKTSFESTVKVVKYIRETICDPLVNPIVTPRFAPSCSRELMQQLSKLVKDENIHVQTHLSENKEEIQWVQDLFPECESYTDVYDKYGLLTEKTVLAHCIHLTDAEARVIKQRRCGISHCPISNSSLTSGECRVRWLLDQGIKVGLGTDVSAGHSCSILTTGRQAFAVSRHLAMRETDHAKLSVSECLFLATMGGAQVLRMDETLGTFDVGKQFDAQMIDTNAPGSNVDMFHWQLKNPPLLTNEDIIAKWFFNGDDRNTTKVWVAGQQVYQI 6oha A 2.21 BS01 XAN A 1 H102 Q105 L117 W120 L121 R231 F232 H258 E261 H297 D348 H83 Q86 L98 W101 L102 R212 F213 H239 E242 H278 D329 3.5.4.3 Q07729 31283204 DKHGKFLVFFGTFVDTPKLGELRIREKTSVGVLNGIIRFVNRNSLDPVKDCLDHDSSLSPEDVTVVDINNSFYFPGFVDTHNHVSQYPNVGVFGNSTLLDWLEKYTFPIEAALANENIAREVYNKVISKTLSHGTTTVAYYNTIDLKSTKLLAQLSSLLGQRVLVGKVCMDTNGPEYYIEDTKTSFESTVKVVKYIRETICDPLVNPIVTPRFAPSCSRELMQQLSKLVKDENIHVQTHLSENKEEIQWVQDLFPECESYTDVYDKYGLLTEKTVLAHCIHLTDAEARVIKQRRCGISHCPISNSSLTSGECRVRWLLDQGIKVGLGTDVSAGHSCSILTTGRQAFAVSRHLAMRETDHAKLSVSECLFLATMGGAQVLRMDETLGTFDVGKQFDAQMIDTNAPGSNVDMFHWQLNPPLLTNEDIIAKWFFNGDDRNTTKVWVAGQQVYQI 6ohb A 2.30 BS01 ZN A 1 H82 H84 H237 D327 H78 H80 H233 D323 3.5.4.3 P76641 31283204 EHTLKAVRGSFIDVTRTIDNPEEIASALRFIEDGLLLIKQGKVEWFGEWENGKHQIPDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLNKHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINMRMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQMAMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHCVHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFNMLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEPTATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN 6ojr A 2.30 BS01 MG A 1 R347 D372 K375 T390 W405 R346 D371 K374 T385 W400 1.13.11.43 Q53353 31292192 AHFPQTPGFSGTLRPLRIEGDILDIEIEGEVPPQLNGTFHRVHPDAQFPPRFEDDQFFNGDGMVSLFRFHDGKIDFRQRYAQTDKWKVERKAGKSLFGAYRNPLTDDASVQGMIRGTANTNVMVHAGKLYAMKEDSPCLIMDPLTLETEGYTNFDGKLQSQTFCAHPKIDPVTGNLCAFAYGAKGLMTLDMAYIEISPTGKLLKEIPFQNPYYCMMHDFGVTEDYAVFAVMPLLSSWDRLEQRLPFFGFDTTLPCYLGILPRNGDARDLRWFKTGNCFVGHVMNAFNDGTKVHIDMPVSRNNSFPFFDVHGAPFDPVAGQGFLTRWTVDMASNGDSFEKTERLFDRPDEFPRIDERYATRAYRHGWMLILDTEKPYEAPYALTNTLGHIDLATGKSSSWWAGPRCAIQEPCFIPRSPDAPEGDGYVIALVDDHVANYSDLAIFDAQHVDQGPIARAKLPVRIRQGLHGNWADASRLAA 6ojr A 2.30 BS02 MG A 2 R353 I354 E356 R352 I353 E355 1.13.11.43 Q53353 31292192 AHFPQTPGFSGTLRPLRIEGDILDIEIEGEVPPQLNGTFHRVHPDAQFPPRFEDDQFFNGDGMVSLFRFHDGKIDFRQRYAQTDKWKVERKAGKSLFGAYRNPLTDDASVQGMIRGTANTNVMVHAGKLYAMKEDSPCLIMDPLTLETEGYTNFDGKLQSQTFCAHPKIDPVTGNLCAFAYGAKGLMTLDMAYIEISPTGKLLKEIPFQNPYYCMMHDFGVTEDYAVFAVMPLLSSWDRLEQRLPFFGFDTTLPCYLGILPRNGDARDLRWFKTGNCFVGHVMNAFNDGTKVHIDMPVSRNNSFPFFDVHGAPFDPVAGQGFLTRWTVDMASNGDSFEKTERLFDRPDEFPRIDERYATRAYRHGWMLILDTEKPYEAPYALTNTLGHIDLATGKSSSWWAGPRCAIQEPCFIPRSPDAPEGDGYVIALVDDHVANYSDLAIFDAQHVDQGPIARAKLPVRIRQGLHGNWADASRLAA 6ojr A 2.30 BS03 MG A 3 T388 A411 I412 Q469 T383 A406 I407 Q464 1.13.11.43 Q53353 31292192 AHFPQTPGFSGTLRPLRIEGDILDIEIEGEVPPQLNGTFHRVHPDAQFPPRFEDDQFFNGDGMVSLFRFHDGKIDFRQRYAQTDKWKVERKAGKSLFGAYRNPLTDDASVQGMIRGTANTNVMVHAGKLYAMKEDSPCLIMDPLTLETEGYTNFDGKLQSQTFCAHPKIDPVTGNLCAFAYGAKGLMTLDMAYIEISPTGKLLKEIPFQNPYYCMMHDFGVTEDYAVFAVMPLLSSWDRLEQRLPFFGFDTTLPCYLGILPRNGDARDLRWFKTGNCFVGHVMNAFNDGTKVHIDMPVSRNNSFPFFDVHGAPFDPVAGQGFLTRWTVDMASNGDSFEKTERLFDRPDEFPRIDERYATRAYRHGWMLILDTEKPYEAPYALTNTLGHIDLATGKSSSWWAGPRCAIQEPCFIPRSPDAPEGDGYVIALVDDHVANYSDLAIFDAQHVDQGPIARAKLPVRIRQGLHGNWADASRLAA 6ojt B 3.00 BS01 NSL B 1 F59 Y101 K134 E135 M216 H218 H282 S304 F305 F308 E350 F58 Y100 K133 E134 M215 H217 H281 S303 F304 F307 E349 1.13.11.43 Q53353 31292192 AHFPQTPGFSGTLRPLRIEGDILDIEIEGEVPPQLNGTFHRVHPDAQFPPRFEDDQFFNGDGMVSLFRFHDGKIDFRQRYAQTDKWKVERKAGKSLFGAYRNPLTDDASVQGMIRGTANTNVMVHAGKLYAMKEDSPCLIMDPLTLETEGYTNFDGKLQSQTFCAHPKIDPVTGNLCAFAYGAKGLMTLDMAYIEISPTGKLLKEIPFQNPYYCMMHDFGVTEDYAVFAVMPLLSSWDRLEQRLPFFGFDTTLPCYLGILPRNGDARDLRWFKTGNCFVGHVMNAFNDGTKVHIDMPVSRNNSFPFFDVHGAPFDPVAGQGFLTRWTVDMASNGDSFEKTERLFDRPDEFPRIDERYATRAYRHGWMLILDTEKPYEAPGGAFYALTNTLGHIDLATGKSSSWWAGPRCAIQEPCFIPRSPDAPEGDGYVIALVDDHVANYSDLAIFDAQHVDQGPIARAKLPVRIRQGLHGNWADASRLA 6ojt B 3.00 BS02 FE B 1 T121 H167 H218 H282 H472 T120 H166 H217 H281 H471 1.13.11.43 Q53353 31292192 AHFPQTPGFSGTLRPLRIEGDILDIEIEGEVPPQLNGTFHRVHPDAQFPPRFEDDQFFNGDGMVSLFRFHDGKIDFRQRYAQTDKWKVERKAGKSLFGAYRNPLTDDASVQGMIRGTANTNVMVHAGKLYAMKEDSPCLIMDPLTLETEGYTNFDGKLQSQTFCAHPKIDPVTGNLCAFAYGAKGLMTLDMAYIEISPTGKLLKEIPFQNPYYCMMHDFGVTEDYAVFAVMPLLSSWDRLEQRLPFFGFDTTLPCYLGILPRNGDARDLRWFKTGNCFVGHVMNAFNDGTKVHIDMPVSRNNSFPFFDVHGAPFDPVAGQGFLTRWTVDMASNGDSFEKTERLFDRPDEFPRIDERYATRAYRHGWMLILDTEKPYEAPGGAFYALTNTLGHIDLATGKSSSWWAGPRCAIQEPCFIPRSPDAPEGDGYVIALVDDHVANYSDLAIFDAQHVDQGPIARAKLPVRIRQGLHGNWADASRLA 6ojt A 3.00 BS02 FE A 1 H167 H218 H282 H472 H166 H217 H281 H471 1.13.11.43 Q53353 31292192 AHFPQTPGFSGTLRPLRIEGDILDIEIEGEVPPQLNGTFHRVHPDAQFPPRFEDDQFFNGDGMVSLFRFHDGKIDFRQRYAQTDKWKVERKAGKSLFGAYRNPLTDDASVQGMIRGTANTNVMVHAGKLYAMKEDSPCLIMDPLTLETEGYTNFDGKLQSQTFCAHPKIDPVTGNLCAFAYGAKGLMTLDMAYIEISPTGKLLKEIPFQNPYYCMMHDFGVTEDYAVFAVMPLLSSWDRLEQRLPFFGFDTTLPCYLGILPRNGDARDLRWFKTGNCFVGHVMNAFNDGTKVHIDMPVSRNNSFPFFDVHGAPFDPVAGQGFLTRWTVDMASNGDSFEKTERLFDRPDEFPRIDERYATRAYRHGWMLILDTEKPYEAPGGAFYALTNTLGHIDLATGKSSSWWAGPRCAIQEPCFIPRSPDAPEGDGYVIALVDDHVANYSDLAIFDAQHVDQGPIARAKLPVRIRQGLHGNWADASRLA 6ojw A 2.60 BS02 MG A 1 Y442 D444 K462 L463 Y441 D443 K461 L462 1.13.11.43 Q53353 31292192 AHFPQTPGFSGTLRPLRIEGDILDIEIEGEVPPQLNGTFHRVHPDAQFPPRFEDDQFFNGDGMVSLFRFHDGKIDFRQRYAQTDKWKVERKAGKSLFGAYRNPLTDDASVQGMIRGTANTNVMVHAGKLYAMKEDSPCLIMDPLTLETEGYTNFDGKLQSQTFCAHPKIDPVTGNLCAFAYGAKGLMTLDMAYIEISPTGKLLKEIPFQNPYYCMMHDFGVTEDYAVFAVMPLLSSWDRLEQRLPFFGFDTTLPCYLGILPRNGDARDLRWFKTGNCFVGHVMNAFNDGTKVHIDMPVSRNNSFPFFDVHGAPFDPVAGQGFLTRWTVDMASNGDSFEKTERLFDRPDEFPRIDERYATRAYRHGWMLILDTEKPYEAPGGAFYALTNTLGHIDLATGKSSSWWAGPRCAIQEPCFIPRSPDAPEGDGYVIALVDDHVANYSDLAIFDAQHVDQGPIARAKLPVRIRQGLHGNWADASRL 6omp A 1.70 BS01 MN A 1 D10 H12 H189 E241 D308 D10 H12 H189 E241 D308 A0A0A0UVH9 MEKLWLNSADSHVLEPDDLWERALPAALRDRAPRCVRDNGRETVYVDGQVVRRDPLDFADAMRPPGALDHHIRLKDLDDQGIWGEVVFPSRGLWTAVMTDPVLARECIKVYNDWLKSDFLSLSPRLVGAAMVSMLDTDDAVAELRRAADLGYQTVFLAATPPPGREFNMDVWEPLWAAAEEAGMTVSIHIGTGADTVVARGPGGAVINYVETLFPAQRAVAQLVASGALDRHPGLRVLIAEAGCAWVPALADRMDEAYRQHGMFVRPKLSMLPGELVRRQVYASFQHDETAIGAVTAMNYTNVLWGSDYPHLEGTFPRTQEVVTELFAGVDPEVRDLITRRNFTDLFTVPALPATV 6omp A 1.70 BS02 MN A 2 E241 D308 H311 E313 E241 D308 H311 E313 A0A0A0UVH9 MEKLWLNSADSHVLEPDDLWERALPAALRDRAPRCVRDNGRETVYVDGQVVRRDPLDFADAMRPPGALDHHIRLKDLDDQGIWGEVVFPSRGLWTAVMTDPVLARECIKVYNDWLKSDFLSLSPRLVGAAMVSMLDTDDAVAELRRAADLGYQTVFLAATPPPGREFNMDVWEPLWAAAEEAGMTVSIHIGTGADTVVARGPGGAVINYVETLFPAQRAVAQLVASGALDRHPGLRVLIAEAGCAWVPALADRMDEAYRQHGMFVRPKLSMLPGELVRRQVYASFQHDETAIGAVTAMNYTNVLWGSDYPHLEGTFPRTQEVVTELFAGVDPEVRDLITRRNFTDLFTVPALPATV 6omp A 1.70 BS03 MN A 3 L312 G314 F316 L312 G314 F316 A0A0A0UVH9 MEKLWLNSADSHVLEPDDLWERALPAALRDRAPRCVRDNGRETVYVDGQVVRRDPLDFADAMRPPGALDHHIRLKDLDDQGIWGEVVFPSRGLWTAVMTDPVLARECIKVYNDWLKSDFLSLSPRLVGAAMVSMLDTDDAVAELRRAADLGYQTVFLAATPPPGREFNMDVWEPLWAAAEEAGMTVSIHIGTGADTVVARGPGGAVINYVETLFPAQRAVAQLVASGALDRHPGLRVLIAEAGCAWVPALADRMDEAYRQHGMFVRPKLSMLPGELVRRQVYASFQHDETAIGAVTAMNYTNVLWGSDYPHLEGTFPRTQEVVTELFAGVDPEVRDLITRRNFTDLFTVPALPATV 6omp B 1.70 BS03 MN B 3 L312 G314 L312 G314 A0A0A0UVH9 MEKLWLNSADSHVLEPDDLWERALPAALRDRAPRCVRDNGRETVYVDGQVVRRDPLDFADAMRPPGALDHHIRLKDLDDQGIWGEVVFPSRGLWTAVMTDPVLARECIKVYNDWLKSDFLSLSPRLVGAAMVSMLDTDDAVAELRRAADLGYQTVFLAATPPPGREFNMDVWEPLWAAAEEAGMTVSIHIGTGADTVVARGPGGAVINYVETLFPAQRAVAQLVASGALDRHPGLRVLIAEAGCAWVPALADRMDEAYRQHGMFVRPKLSMLPGELVRRQVYASFQHDETAIGAVTAMNYTNVLWGSDYPHLEGTFPRTQEVVTELFAGVDPEVRDLITRRNFTDLFTVPALPATV 6omq B 1.86 BS01 MZD B 1 R52 M62 I190 G191 T196 A199 R200 G204 A205 N208 Y209 E313 R52 M62 I190 G191 T196 A199 R200 G204 A205 N208 Y209 E313 A0A0A0UVH9 MEKLWLNSADSHVLEPDDLWERALPAALRDRAPRCVRDNGRETVYVDGQVVRRDPLDFADAMRPPGALDHHIRLKDLDDQGIWGEVVFPSRGLWTAVMTDPVLARECIKVYNDWLKSDFLSLSPRLVGAAMVSMLDTDDAVAELRRAADLGYQTVFLAATPPPGREFNMDVWEPLWAAAEEAGMTVSIHIGTGADTVVARGPGGAVINYVETLFPAQRAVAQLVASGALDRHPGLRVLIAEAGCAWVPALADRMDEAYRQHGMFVRPKLSMLPGELVRRQVYASFQHDETAIGAVTAMNYTNVLWGSDYPHLEGTFPRTQEVVTELFAGVDPEVRDLITRRNFTDLFTVPALPATV 6omr B 2.45 BS01 MYM B 1 R52 M62 S90 L93 W94 I190 G191 T196 A199 R200 A205 N208 Y209 T212 E313 R52 M62 S90 L93 W94 I190 G191 T196 A199 R200 A205 N208 Y209 T212 E313 A0A0A0UVH9 MEKLWLNSADSHVLEPDDLWERALPAALRDRAPRCVRDNGRETVYVDGQVVRRDPLDFADAMRPPGALDHHIRLKDLDDQGIWGEVVFPSRGLWTAVMTDPVLARECIKVYNDWLKSDFLSLSPRLVGAAMVSMLDTDDAVAELRRAADLGYQTVFLAATPPPGREFNMDVWEPLWAAAEEAGMTVSIHIGTGADTVVARGPGGAVINYVETLFPAQRAVAQLVASGALDRHPGLRVLIAEAGCAWVPALADRMDEAYRQHGMFVRPKLSMLPGELVRRQVYASFQHDETAIGAVTAMNYTNVLWGSDYPHLEGTFPRTQEVVTELFAGVDPEVRDLITRRNFTDLFTVPALPATV 6or7 A 2.53 BS01 NUC P 1 Y183 M184 D185 M230 G231 N255 C258 K259 G262 K263 W266 L283 L289 R358 G359 A360 H361 T473 Q475 K476 Y501 Y175 M176 D177 M222 G223 N247 C250 K251 G254 K255 W258 L275 L281 R350 G351 A352 H353 T465 Q467 K468 Y493 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 6or7 A 2.53 BS02 NUC T 1 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 Q151 G152 K154 P157 Y183 S280 R284 G285 A355 R356 N474 Q500 H539 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 Q143 G144 K146 P149 Y175 S272 R276 G277 A347 R348 N466 Q492 H531 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 6or7 A 2.53 BS03 1RY A 1 K65 R72 V111 G112 D113 A114 Y115 Q151 M184 D185 K220 K65 R72 V111 G112 D113 A114 Y115 Q143 M176 D177 K212 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 6otz A 2.86 BS02 NUC T 1 W24 K30 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 Q151 G152 K154 P157 Y183 V276 S280 R284 K374 R448 N474 Q500 H539 W24 K30 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 Q151 G152 K154 P157 Y183 V276 S280 R284 K374 R448 N474 Q500 H539 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 6otz A 2.86 BS05 N8G A 1 K65 R72 D110 G112 D113 A114 Y115 Q151 D185 K220 K65 R72 D110 G112 D113 A114 Y115 Q151 D185 K220 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 6oun A 2.66 BS01 NUC P 1 Y183 D185 M230 G231 N255 C258 K259 G262 K263 W266 L283 L289 R358 G359 A360 H361 R448 T473 Q475 K476 Y501 I505 Y174 D176 M221 G222 N246 C249 K250 G253 K254 W257 L274 L280 R349 G350 A351 H352 R439 T464 Q466 K467 Y492 I496 2.7.7.49,2.7.7.7,3.1.26.13 P03366 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAG 6oun A 2.66 BS02 NUC T 1 L26 F61 L74 R78 N81 E89 Q91 L92 I94 G152 P157 Y183 S280 R284 G285 K353 N474 H539 L26 F61 L74 R78 N81 E89 Q91 L92 I94 G143 P148 Y174 S271 R275 G276 K344 N465 H530 2.7.7.49,2.7.7.7,3.1.26.13 P03366 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAG 6oun A 2.66 BS05 1RZ A 1 R72 D110 V111 G112 D113 A114 Y115 Q151 M184 D185 R72 D110 V111 G112 D113 A114 Y115 Q142 M175 D176 2.7.7.49,2.7.7.7,3.1.26.13 P03366 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAG 6ovr C 2.84 BS02 NUC I 1 K188 Q390 Q393 F394 H406 L413 T419 R420 N448 I452 Q567 K838 K846 H999 K181 Q383 Q386 F387 H399 L406 T412 R413 N437 I441 Q556 K827 K835 H988 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6ovr D 2.84 BS01 NUC G 1 K106 R586 K610 R615 R622 R628 A705 P706 T1088 A1089 G1092 Y1093 N1442 K104 R584 K608 R613 R620 R626 A703 P704 T1086 A1087 G1090 Y1091 N1424 2.7.7.6 Q8RQE8 KEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEILAELPEPYLFRAEEEGVVELKELEEGAFLVLRREDEPVATYFLPVGMTPLVVHGEIVEKGQPLAEAKGLLRMPRQVRAAQVEAEEEGETVYLTLFLEWTEPKDYRVQPHMNVVVPEGARVEAGDKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTQGLPRVIELFEARRPKAKAVISEIDGVVRIEETEEKLSVFVESEGFSKEYKLPKEARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEA 6ovr F 2.84 BS02 NUC H 1 D79 V81 R82 L85 H86 G89 N191 R193 L194 V196 S197 F209 K226 F227 E228 R231 F233 K234 S236 T237 Y238 T240 W241 D2 V4 R5 L8 H9 G12 N114 R116 L117 V119 S120 F132 K149 F150 E151 R154 F156 K157 S159 T160 Y161 T163 W164 Q5SKW1 SDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDPDLIREVVRAKILGSARVRHIPGLKETLDPKTVEEIDQKLKSLPKEHKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAFFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD 6ovy C 3.00 BS02 NUC I 1 Q390 Q393 L413 R420 N448 I452 K838 K846 H999 Q383 Q386 L406 R413 N441 I445 K831 K839 H992 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6ovy D 3.00 BS03 NUC I 1 R704 A705 D741 D743 R701 A702 D738 D740 2.7.7.6 Q8RQE8 EVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEILAELPEPYLFRAEEEGVVELKELEEGAFLVLRREDEPVATYFLPVGMTPLVVHGEIVEKGQPLAEAKGLLRMPRQVRAAQVEAEEEGETVYLTLFLEWTEPKDYRVQPHMNVVVPEGARVEAGDKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEETEEKLSVFVESEGFSKEYKLPKEARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEA 6ow3 C 2.77 BS01 NUC G 1 R134 E421 G1023 K1024 R1031 M1035 R127 E414 G1016 K1017 R1024 M1028 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6ow3 C 2.77 BS02 NUC H 1 K167 W171 R243 G245 E421 R422 K160 W164 R236 G238 E414 R415 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6ow3 C 2.77 BS03 NUC I 1 Q390 R409 R420 N448 I452 Q567 K838 K846 H999 Q383 R402 R413 N441 I445 Q560 K831 K839 H992 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6ow3 D 2.77 BS01 NUC G 1 R586 K610 R615 R622 R628 A705 T1088 A1089 G1092 Y1093 N1442 R584 K608 R613 R620 R626 A703 T1086 A1087 G1090 Y1091 N1424 2.7.7.6 Q8RQE8 KEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEILAELPEPYLFRAEEEGVVELKELEEGAFLVLRREDEPVATYFLPVGMTPLVVHGEIVEKGQPLAEAKGLLRMPRQVRAAQVEAEEEGETVYLTLFLEWTEPKDYRVQPHMNVVVPEGARVEAGDKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTQGLPRVIELFEARRPKAKAVISEIDGVVRIEETEEKLSVFVESEGFSKEYKLPKEARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEA 6ow3 D 2.77 BS02 NUC H 1 V108 P109 R1266 K1426 V106 P107 R1248 K1408 2.7.7.6 Q8RQE8 KEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEILAELPEPYLFRAEEEGVVELKELEEGAFLVLRREDEPVATYFLPVGMTPLVVHGEIVEKGQPLAEAKGLLRMPRQVRAAQVEAEEEGETVYLTLFLEWTEPKDYRVQPHMNVVVPEGARVEAGDKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTQGLPRVIELFEARRPKAKAVISEIDGVVRIEETEEKLSVFVESEGFSKEYKLPKEARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEA 6oy7 C 3.04 BS01 NUC G 1 R134 F394 E421 G1023 K1024 Q1030 R1031 M1035 R127 F387 E414 G1016 K1017 Q1023 R1024 M1028 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6oy7 C 3.04 BS02 NUC H 1 W171 R243 E421 R422 W164 R236 E414 R415 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6oy7 C 3.04 BS03 NUC I 1 Q390 Q393 F394 H406 R409 L413 T419 R420 P444 N448 I452 Q567 K838 K846 H999 Q383 Q386 F387 H399 R402 L406 T412 R413 P437 N441 I445 Q560 K831 K839 H992 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6oy9 R 3.90 BS01 RET R 1 A117 T118 E122 M207 W265 Y268 A269 A272 K296 A117 T118 E122 M207 W265 Y268 A269 A272 K296 P02699 31300275 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN 6oya R 3.30 BS01 RET R 1 M86 A117 E122 Y191 M207 H211 W265 Y268 K296 M86 A117 E122 Y191 M207 H211 W265 Y268 K296 P02699 31300275 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN 6p10 B 2.30 BS01 SKE B 1 D484 I485 A486 G526 C527 G528 L531 R534 L659 G688 S689 T692 D25 I26 A27 G67 C68 G69 L72 R75 L185 G214 S215 T218 5.6.1.1 Q8I0P1 31257183 GVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGCGKTLLARAVATECSATFLNISAASLTSKYGEKLVRALFAVARHMQPSIIFIDEVDSLLSRRLKTEFLVEFDGLPPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGD 6p11 B 2.15 BS01 SKE B 1 D484 I485 A486 G526 N527 G528 L659 L663 K666 G688 S689 D25 I26 A27 G67 N68 G69 L184 L188 K191 G213 S214 5.6.1.1 Q8I0P1 31257183 GVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYGEKLVRALFAVARHMQPSIIFIDEVDSLLSRRLKTEFLVEFDGLPGGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLAALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGD 6p12 B 1.94 BS01 NKY B 1 D484 I485 A486 Q488 N527 G528 L531 S649 L650 P651 T655 L659 L663 G688 S689 T692 D25 I26 A27 Q29 N68 G69 L72 S174 L175 P176 T180 L184 L188 G213 S214 T217 5.6.1.1 Q8I0P1 31257183 GVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYDGELVRALFAVARHMQPSIIFIDEVDSLLSRRLKTEFLVEFDGLPGNDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGDI 6p14 A 1.93 BS01 NKY A 1 D484 I485 A486 Q488 G526 N527 G528 L531 S649 L650 P651 T655 L659 G688 S689 D28 I29 A30 Q32 G70 N71 G72 L75 S160 L161 P162 T166 L170 G199 S200 5.6.1.1 Q8I0P1 31257183 VVSVKEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISKLVRALFAVARHMQPSIIFIDEVDSLRLKTEFLVEFDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLAALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYG 6p1i A 2.74 BS01 NUC P 1 Y183 D186 M230 G231 C258 K259 G262 K263 W266 L283 L289 G359 A360 H361 R448 K451 T473 Q475 K476 Y501 Y177 D180 M224 G225 C252 K253 G256 K257 W260 L277 L283 G353 A354 H355 R442 K445 T467 Q469 K470 Y495 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSIIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 6p1i A 2.74 BS03 DCP A 1 R72 D110 V111 G112 D113 A114 Y115 Q151 D185 K220 R72 D110 V111 G112 D113 A114 Y115 Q145 D179 K214 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSIIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 6p2g A 2.99 BS01 NUC P 1 Y183 M230 G231 N255 C258 K259 G262 K263 W266 L283 R358 G359 A360 H361 R448 K451 T473 Q475 Y501 Y174 M221 G222 N246 C249 K250 G253 K254 W257 L274 R349 G350 A351 H352 R439 K442 T464 Q466 Y492 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 6p2g A 2.99 BS02 NUC T 1 F61 L74 D76 R78 N81 E89 Q91 I94 Q151 G152 K154 P157 Y183 N265 S280 R284 K353 N474 Q500 H539 F61 L74 D76 R78 N81 E89 Q91 I94 Q142 G143 K145 P148 Y174 N256 S271 R275 K344 N465 Q491 H530 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 6p2g A 2.99 BS03 DCT A 1 R72 D110 V111 G112 D113 A114 Y115 Q151 R72 D110 V111 G112 D113 A114 Y115 Q142 2.7.7.49,2.7.7.7,3.1.26.13 P04585 31301259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 6p2i A 1.63 BS01 NAP A 1 T74 S98 V102 G149 I150 G151 Q152 I153 L171 N172 K173 S174 R176 H199 I200 P201 T206 T227 C228 D253 A276 W277 T74 S98 V102 G149 I150 G151 Q152 I153 L171 N172 K173 S174 R176 H199 I200 P201 T206 T227 C228 D253 A276 W277 A0A1I4FUG4 31298853 MKITYIDKPTYLPSWVINKINEYGDFEVFYDFPNEEEAINRLSSTDIAIVEWTSITKEMIEKISRLKYLITITTSYDYIDVNSLKDNEIMVSNCPQYSKQAVAEHVFALLFAVNRKILQADETCRKGLSHIYPPFLCSEIRDKTIGLIGIGQIGQTVAEIANAFQMKVIGLNKSKRNVKGIQQVDITELMKKSDIISLHIPRNADTEIILTEKLLSLMKPDAVLINTCRGNLIDEQALYSVLKQNRIRGAGLDDLTYYKDNPIIGLNNVVLTPGSAWYSYEAREKNMYELIENIESYLAQKPVNVIL 6p2i A 1.63 BS02 DAR A 1 E51 I72 T73 T74 S75 Y97 R229 W277 N286 E51 I72 T73 T74 S75 Y97 R229 W277 N286 A0A1I4FUG4 31298853 MKITYIDKPTYLPSWVINKINEYGDFEVFYDFPNEEEAINRLSSTDIAIVEWTSITKEMIEKISRLKYLITITTSYDYIDVNSLKDNEIMVSNCPQYSKQAVAEHVFALLFAVNRKILQADETCRKGLSHIYPPFLCSEIRDKTIGLIGIGQIGQTVAEIANAFQMKVIGLNKSKRNVKGIQQVDITELMKKSDIISLHIPRNADTEIILTEKLLSLMKPDAVLINTCRGNLIDEQALYSVLKQNRIRGAGLDDLTYYKDNPIIGLNNVVLTPGSAWYSYEAREKNMYELIENIESYLAQKPVNVIL 6p2i B 1.63 BS02 DAR B 1 E51 I72 T73 T74 S75 Y97 W277 N286 E51 I72 T73 T74 S75 Y97 W277 N286 A0A1I4FUG4 31298853 MKITYIDKPTYLPSWVINKINEYGDFEVFYDFPNEEEAINRLSSTDIAIVEWTSITKEMIEKISRLKYLITITTSYDYIDVNSLKDNEIMVSNCPQYSKQAVAEHVFALLFAVNRKILQADETCRKGLSHIYPPFLCSEIRDKTIGLIGIGQIGQTVAEIANAFQMKVIGLNKSKRNVKGIQQVDITELMKKSDIISLHIPRNADTEIILTEKLLSLMKPDAVLINTCRGNLIDEQALYSVLKQNRIRGAGLDDLTYYKDNPIIGLNNVVLTPGSAWYSYEAREKNMYELIENIESYLAQKPVNVIL 6p46 A 3.50 BS01 CA A 1 E624 E670 D703 E458 E504 D537 Q6P9J9 31291589 DFRTPEFEEFNGKPDSLFFTDGQRRIDFILVYEDESKKGTNEKQKRKRQAYESNLICLVFVKVHAPWEVLCTYAEIMHIKLPFEKSRMNDFYNPATRSRIVYFILSRVKYQVMNNVNKFGINRLVSSGIYKAAFPLHDCSERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLDQDNCTWSKEVCDPDIGGQILMCPQCDRLCPFWRLNITCESSKKLCIFDSFGTLIFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELTTCGKCIRVTLCASAVFFWILLIIASVIGIIVYRLSVFIVFSTTLKYLTPQMATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYLLGKYRSEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVMNLIGRYKRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITCRYRDFRNPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHIIYSVKFFISYAIPDVSKITKSKIKREKYLT 6p49 A 3.30 BS01 CA A 1 N621 E667 E670 D703 N363 E409 E412 D445 Q6P9J9 31291589 TNEKQKRKRQAYESNLLVFVKVHVLCTYAEIMHNPATRSRIVYFILSGINRLVSSGIYKAAFPLERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLDQDNCTWSKEVCDPDIGGQILMCPQCDRLCPFWRLNITCESSKKLCIFDSFGTLIFAVFMGVWVTLFLEFWKRRQAELEYEWDTVTLCASAVFFWILLIIASVIGIIVYRLSVFIVFSLTPQMATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYLLGKYRSEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVMNLIGRYKRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITCRYRDFRNPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHIIYSVKFFISYAIPDV 6p71 C 2.92 BS02 NUC H 1 R243 E421 R422 R236 E414 R415 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6p71 C 2.92 BS03 NUC I 1 R409 R420 N448 Q567 K838 K846 H999 R402 R413 N441 Q560 K831 K839 H992 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 6p71 D 2.92 BS07 UTP D 1 R704 P706 N737 D739 R1029 Q1235 M1238 R1239 H1242 R702 P704 N735 D737 R1027 Q1233 M1236 R1237 H1240 2.7.7.6 Q8RQE8 KEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEILAELPEPYLFRAEEEGVVELKELEEGAFLVLRREDEPVATYFLPVGMTPLVVHGEIVEKGQPLAEAKGLLRMPRQVRAAQVEAEEEGETVYLTLFLEWTEPKDYRVQPHMNVVVPEGARVEAGDKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAVISEIDGVVRIEETEEKLSVFVESEGFSKEYKLPKEARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEA 6pcw A 2.20 BS02 O97 A 1 F49 A65 K67 L120 E121 V126 L174 I185 D186 F18 A34 K36 L88 E89 V94 L142 I153 D154 2.7.11.1 P11309 EPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 6pdi A 1.85 BS02 OCJ A 1 L44 S46 F49 A65 K67 L120 E121 D128 L174 I185 L13 S15 F18 A34 K36 L89 E90 D97 L143 I154 2.7.11.1 P11309 EPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 6pdn A 2.40 BS02 OD4 A 1 V52 A65 K67 I104 E121 V126 L174 I185 D186 V17 A30 K32 I69 E86 V91 L139 I150 D151 2.7.11.1 P11309 EPLESQYQVGPLLGSSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 6pdo A 2.40 BS01 III B 1 D128 F130 D131 I133 T134 D167 K169 D170 E171 D202 T204 V206 D234 G238 D239 I240 E243 D90 F92 D93 I95 T96 D129 K131 D132 E133 D164 T166 V168 D196 G200 D201 I202 E205 2.7.11.1 P11309 ESQYQVGPLLGSSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 6pdo A 2.40 BS02 OD1 A 1 A65 K67 L120 E121 D131 L174 I185 D186 A27 K29 L82 E83 D93 L136 I147 D148 2.7.11.1 P11309 ESQYQVGPLLGSSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 6pdp A 2.50 BS02 OBY A 1 L44 V52 A65 K67 I104 L120 E121 V126 L174 I185 D186 L9 V15 A28 K30 I67 L83 E84 V89 L137 I148 D149 2.7.11.1 P11309 SQYQVGPLLGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 6pfl A 2.10 BS01 APR A 1 W1619 Y1630 Y1658 Q1667 N1669 T1672 N1674 R1676 W7 Y18 Y46 Q55 N57 T60 N62 R64 2.3.2.26 Q7Z6Z7 NSNNWRWFDDRSGRWCSYSASNNSTIDSAWKSGETSVRFTAGRRRYTVQFTTMVQVNEETGNRRPVMLTLLRVPRL 6pfl B 2.10 BS01 APR B 1 W1619 Y1630 R1656 Y1658 Q1667 N1669 T1672 N1674 R1676 W7 Y18 R44 Y46 Q55 N57 T60 N62 R64 2.3.2.26 Q7Z6Z7 NSNNWRWFDDRSGRWCSYSASNNSTIDSAWKSGETSVRFTAGRRRYTVQFTTMVQVNEETGNRRPVMLTLLRVPRLN 6pgn A 1.85 BS01 GPP A 1 R65 K136 H138 R140 L170 E184 Y186 E188 L220 A222 Y235 W271 R288 Y290 R65 K136 H138 R140 L170 E184 Y186 E188 L220 A222 Y235 W271 R288 Y290 2.-.-.- A0A1J1JDI6 29924593 MIVNVIQKDRLKEQKLQFIRNHQQAFDVEPIYPLPLFEDFVTSIEGDCSLEASCKIESDKLIASRFLLFFEDKTQEWQKYLHQSLTFFGLVENRVGVKINYSLLQQFLGSSFDFSKVTVLSAGIDLRNNLAESSLKMHIRIKDYPEKLDKAFALSDGAADGNYLKDFVNLIGFDFYFNGKSEIEIYAEVQEDDFFKPEINNLVWQHFPKTALQPLKASSLFATGLSKANNNPVLYYHLKNRQDLTNYFKLNDTAQRVHSFYQHQDILPYMWVGTAQKELEKTRIENIRLYYYKSFKM 6pi7 A 2.80 BS01 III G 1 S315 E316 H320 W322 L376 D385 N394 E433 L436 D437 D440 S10 E11 H15 W17 L71 D80 N89 E128 L131 D132 D135 Q9Y2W6 31288074 EYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPE 6plf A 1.70 BS01 ONV A 1 G152 Y174 D175 P176 I177 I178 L193 H206 T207 P208 S212 T213 L216 G148 Y170 D171 P172 I173 I174 L189 H202 T203 P204 S208 T209 L212 1.1.1.95,1.1.1.399,1.1.1.37 O43175 NLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKG 6plg A 2.93 BS01 ONS A 1 L153 G154 R155 I156 Y174 D175 P176 I177 I178 H206 T207 P208 L210 A235 R236 L148 G149 R150 I151 Y169 D170 P171 I172 I173 H201 T202 P203 L205 A230 R231 1.1.1.95,1.1.1.399,1.1.1.37 O43175 LRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVK 6plg B 2.93 BS01 ONS B 1 G154 R155 I156 Y174 D175 P176 I177 I178 H206 T207 P208 L210 T213 R236 G149 R150 I151 Y169 D170 P171 I172 I173 H201 T202 P203 L205 T208 R231 1.1.1.95,1.1.1.399,1.1.1.37 O43175 LRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVK 6plg C 2.93 BS01 ONS C 1 G152 G154 R155 I156 Y174 D175 P176 I177 I178 H206 T207 L210 T213 L216 A235 R236 G147 G149 R150 I151 Y169 D170 P171 I172 I173 H201 T202 L205 T208 L211 A230 R231 1.1.1.95,1.1.1.399,1.1.1.37 O43175 LRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVK 6plg E 2.93 BS01 ONS E 1 G152 G154 R155 I156 Y174 D175 P176 I177 I178 H206 T207 L210 S212 T213 L216 R236 G146 G148 R149 I150 Y168 D169 P170 I171 I172 H200 T201 L204 S206 T207 L210 R230 1.1.1.95,1.1.1.399,1.1.1.37 O43175 RKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVK 6plg F 2.93 BS01 ONS F 1 L151 G152 G154 R155 I156 Y174 D175 P176 I177 H206 T207 P208 L210 L216 A235 R236 L143 G144 G146 R147 I148 Y166 D167 P168 I169 H198 T199 P200 L202 L208 A227 R228 1.1.1.95,1.1.1.399,1.1.1.37 O43175 VLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 6plg H 2.93 BS01 ONS H 1 G154 R155 I156 Y174 D175 P176 I177 I178 H206 T207 P208 L210 S212 T213 L216 A235 G149 R150 I151 Y169 D170 P171 I172 I173 H201 T202 P203 L205 S207 T208 L211 A230 1.1.1.95,1.1.1.399,1.1.1.37 O43175 LRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVK 6pnm A 1.82 BS01 XX0 A 1 C32 P33 F34 V72 G128 I131 W222 L226 Y229 C30 P31 F32 V70 G126 I129 W220 L224 Y227 2.5.1.18,1.8.5.1,1.20.4.2 P78417 GESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL 6pnn A 2.10 BS01 OR7 A 1 M29 C32 P33 F34 V72 V127 G128 I131 F225 Y229 M26 C29 P30 F31 V69 V124 G125 I128 F222 Y226 2.5.1.18,1.8.5.1,1.20.4.2 P78417 ESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL 6pno A 1.82 BS01 ORM A 1 C32 P33 F34 V72 G128 Y229 C30 P31 F32 V70 G126 Y227 2.5.1.18,1.8.5.1,1.20.4.2 P78417 GESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL 6pta A 2.50 BS01 GDP A 1 D26 A27 A28 G29 K30 T31 T32 N126 K127 D129 L130 C159 A160 T161 D17 A18 A19 G20 K21 T22 T23 N112 K113 D115 L116 C145 A146 T147 P22274 LFASLLGEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGPLWRYYFQNTQGIIFVVDSNDRDRINEAREELQSMLNEDELKDAVLLVLANKQDLPNAMNAAEITEKMGLHSIRNRPWFIQATCATTGDGLYEGLEWLSNQVGK 6pta D 2.50 BS01 GDP B 1 I49 N52 I40 N43 P22274 LFASLLGRMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGRPLWRYYFQNTQGIIFVVDSNDRDRINEAREELQSMLNEDELKDAVLLVLANKQDLPNAMNAAEITEKMGLHSIRNRPWFIQATCATTGDGLYEGLEWLSNQVG 6q3k A 1.50 BS01 III P 1 M5 Y7 F9 M45 E63 K66 V67 H70 T73 V76 D77 R97 Y99 Y116 Y123 T143 K146 W147 V152 Y159 T163 W167 Y171 M6 Y8 F10 M46 E64 K67 V68 H71 T74 V77 D78 R98 Y100 Y117 Y124 T144 K147 W148 V153 Y160 T164 W168 Y172 P01892 AGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGCYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMCAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 6q3k A 1.50 BS03 CO A 2 Q218 H260 Q219 H261 P01892 AGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGCYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMCAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 6q3s A 2.50 BS01 III C 1 M5 Y7 F9 Y59 E63 K66 V67 H70 T73 V76 D77 T80 L81 R97 Y99 Y116 Y123 T143 W147 V152 L156 Y159 W167 Y171 M5 Y7 F9 Y59 E63 K66 V67 H70 T73 V76 D77 T80 L81 R97 Y99 Y116 Y123 T143 W147 V152 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGCYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMCAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 6qaj A 2.90 BS01 ZN A 1 C65 C68 C88 C91 C177 C180 C200 C203 3.2.1.17,2.3.2.27 Q13263 31289231 NLYFQGNIFEMLRIDERLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQTPNRAKRVITTFRTGTWDAYAAEALELLEHCGVCRERLRPEREPRLLPCLHSACSACLGPADGTVVDCPVCKQQCFSKDIVENYFMRDSGSERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAF 6qaj A 2.90 BS02 ZN A 2 C83 H85 C117 C120 C195 H197 C214 C217 3.2.1.17,2.3.2.27 Q13263 31289231 NLYFQGNIFEMLRIDERLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQTPNRAKRVITTFRTGTWDAYAAEALELLEHCGVCRERLRPEREPRLLPCLHSACSACLGPADGTVVDCPVCKQQCFSKDIVENYFMRDSGSERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAF 6qaj A 2.90 BS04 ZN A 4 C221 S223 C224 H237 H240 C255 S257 C258 H271 H274 3.2.1.17,2.3.2.27 Q13263 31289231 NLYFQGNIFEMLRIDERLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQTPNRAKRVITTFRTGTWDAYAAEALELLEHCGVCRERLRPEREPRLLPCLHSACSACLGPADGTVVDCPVCKQQCFSKDIVENYFMRDSGSERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAF 6qaj B 2.90 BS01 ZN B 1 C221 C224 H237 H240 C256 C259 H272 H275 3.2.1.17,2.3.2.27 Q13263 31289231 NLYFQGNIFEMLRIDERLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQTPNRAKRVITTFRTGTWDAYAAEALELLEHCGVCRERLRPEREPRLLPCLHSACSACLGPAAAGDGTVVDCPVCKQQCFSKDIVENYFMRDSERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAFG 6qaj B 2.90 BS02 ZN B 2 C209 V211 H212 C229 C232 C244 V246 H247 C264 C267 3.2.1.17,2.3.2.27 Q13263 31289231 NLYFQGNIFEMLRIDERLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQTPNRAKRVITTFRTGTWDAYAAEALELLEHCGVCRERLRPEREPRLLPCLHSACSACLGPAAAGDGTVVDCPVCKQQCFSKDIVENYFMRDSERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAFG 6qqn B 2.30 BS01 GDP B 1 G10 Q11 C12 Q15 I16 S140 G143 G144 T145 G146 P173 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 I16 S138 G141 G142 T143 G144 P171 V175 D177 E181 N204 Y222 N226 Q6B856 31302152 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 6qqn B 2.30 BS03 2GE B 1 N167 T168 F169 E200 Y202 V238 C241 L242 L248 N249 L252 L255 M259 F268 A316 I318 I378 N165 T166 F167 E198 Y200 V236 C239 L240 L246 N247 L250 L253 M257 F266 A309 I311 I363 Q6B856 31302152 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 6qqn F 2.30 BS01 ACP F 1 K74 K150 Q183 K184 Y185 L186 K198 D200 T241 N242 D318 M320 E331 N333 K74 K125 Q143 K144 Y145 L146 K158 D160 T196 N197 D261 M263 E274 N276 E1BQ43 31302152 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPDEREVFLAAYNRRREGGNVWIAKSISSEASELLDFIVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSATCHLTNHYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH 6rb6 A 1.90 BS02 JX2 A 1 M785 D822 I823 A837 V840 M861 G873 Q874 G876 F877 M200 D237 I238 A252 V255 M276 G288 Q289 G291 F292 3.1.4.- Q8WQX9 VTAITKVEREAVLVCELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR 6rb6 B 1.90 BS02 JX2 B 1 M785 I823 V840 T841 F844 Y845 M861 N867 K872 G873 Q874 F877 M200 I238 V255 T256 F259 Y260 M276 N282 K287 G288 Q289 F292 3.1.4.- Q8WQX9 VTAITKVEREAVLVCELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR 6rcw B 2.08 BS02 JX2 B 1 H160 M273 D318 L319 N321 I336 M357 S368 Q369 F372 H72 M185 D230 L231 N233 I248 M269 S280 Q281 F284 3.1.4.53 Q08499 EDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 6rcw C 2.08 BS02 JX2 C 1 H160 M273 D318 L319 N321 I336 M357 S368 Q369 G371 F372 I376 H73 M186 D231 L232 N234 I249 M270 S281 Q282 G284 F285 I289 3.1.4.53 Q08499 QEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 6rfn B 2.29 BS02 K3W B 1 M785 D822 I823 N825 F844 M861 G873 Q874 F877 M200 D237 I238 N240 F259 M276 G288 Q289 F292 3.1.4.- Q8WQX9 VTAITKVEREAVLVCELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLET 6rfw A 2.18 BS02 K1Q A 1 M785 D822 N825 A837 V840 M861 G873 Q874 G876 F877 M200 D237 N240 A252 V255 M276 G288 Q289 G291 F292 3.1.4.- Q8WQX9 VTAITKVEREAVLVCELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLET 6rfw B 2.18 BS02 K1Q B 1 M785 D822 I823 N825 V840 M861 G873 Q874 F877 M200 D237 I238 N240 V255 M276 G288 Q289 F292 3.1.4.- Q8WQX9 VTAITKVEREAVLVCELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLET 6rgk B 2.03 BS02 K3N B 1 M785 I823 N825 V840 F844 M861 M868 G873 Q874 F877 M200 I238 N240 V255 F259 M276 M283 G288 Q289 F292 3.1.4.- Q8WQX9 VTAITKVEREAVLVCELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLET 6rpg A 2.70 BS01 KDW B 1 T20 I54 Y56 D61 Q66 V68 M115 I116 S117 A121 D122 Y123 R125 T3 I37 Y39 D44 Q49 V51 M98 I99 S100 A104 D105 Y106 R108 Q9NZQ7 31298541 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPY 6rpg B 2.70 BS01 KDW B 1 T20 I54 Y56 Q66 M115 I116 S117 A121 D122 Y123 K124 R125 T3 I37 Y39 Q49 M98 I99 S100 A104 D105 Y106 K107 R108 Q9NZQ7 31298541 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPY 6s3f A 1.68 BS01 III B 1 T2 R5 C6 Q9 N12 V13 S14 C17 S21 Q24 A25 S28 A29 Q32 Q33 Q40 H43 M44 V47 T3 R6 C7 Q10 N13 V14 S15 C18 S22 Q25 A26 S29 A30 Q33 Q34 Q41 H44 M45 V48 W5S2D2 31302367 PPTLQRCCRQLRNVSPFCRCPSLRQAVQSAQQQQGQVGPQQVGHMYRVASRIPAICNLQPMRCPF 6s5t A 4.15 BS01 ANP A 1 H492 R500 D502 V510 Q517 Q519 L520 G521 H394 R402 D404 V412 Q419 Q421 L422 G423 Q5ZTK6 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWREARK