5qoh A 1.93 BS01 JGD A 1 F186 N196 I197 F91 N101 I102 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qoi A 1.99 BS01 LD4 A 1 V115 Q116 G117 K121 G125 F126 K128 E148 I194 M227 V20 Q21 G22 K26 G30 F31 K33 E53 I99 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qoj A 2.05 BS01 JG4 A 1 I167 F226 M227 I229 P230 I72 F131 M132 I134 P135 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qok A 2.28 BS01 AWS A 1 A142 R143 F146 D152 K154 A47 R48 F51 D57 K59 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qol A 1.85 BS01 JGP A 1 V115 K121 F126 K128 E148 V20 K26 F31 K33 E53 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qom A 1.87 BS01 LDV A 1 F186 N187 P188 R191 R195 N196 I197 E198 W199 F91 N92 P93 R96 R100 N101 I102 E103 W104 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qon A 1.80 BS01 LDS A 1 S122 G123 P222 N223 K224 S27 G28 P127 N128 K129 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qoo A 1.56 BS01 LDJ A 1 S122 R209 P222 N223 K224 F226 S27 R114 P127 N128 K129 F131 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qop A 1.86 BS01 LDD A 1 K121 F126 K128 G129 E148 Q170 K26 F31 K33 G34 E53 Q75 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qoq A 1.49 BS01 LD7 A 1 G117 A120 K121 G123 G125 E148 I194 M227 G22 A25 K26 G28 G30 E53 I99 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qor A 1.95 BS01 LEY A 1 G117 A120 K121 G123 E148 I194 M227 G22 A25 K26 G28 E53 I99 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qos A 1.70 BS01 LES A 1 V115 F126 K128 E148 I194 M227 V20 F31 K33 E53 I99 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qot A 1.68 BS01 LEJ A 1 G117 A120 K121 S122 G125 E148 I194 F226 M227 G22 A25 K26 S27 G30 E53 I99 F131 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qou A 2.19 BS01 LE7 A 1 V115 G117 A120 K121 G123 G125 E148 I194 F226 M227 V20 G22 A25 K26 G28 G30 E53 I98 F130 M131 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qov A 1.65 BS01 LE4 A 1 V115 G117 K121 G125 F126 K128 E148 I194 M227 F231 V20 G22 K26 G30 F31 K33 E53 I99 M132 F136 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qow A 1.82 BS01 LFP A 1 V115 G117 A120 K121 G125 K128 E148 I194 F226 M227 V20 G22 A25 K26 G30 K33 E53 I99 F131 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qox A 1.95 BS01 LFM A 1 V115 G117 A120 K121 G125 E148 I194 M227 V20 G22 A25 K26 G30 E53 I99 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qoy A 1.69 BS01 LFJ A 1 V115 K121 G125 K128 G129 E148 E193 V20 K26 G30 K33 G34 E53 E98 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qoz A 1.70 BS01 LFG A 1 V115 G117 F126 K128 E148 I194 M227 V20 G22 F31 K33 E53 I99 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qp1 A 1.79 BS01 LJ7 A 1 G117 A120 K121 E148 I194 F226 M227 G22 A25 K26 E53 I99 F131 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qp4 A 1.71 BS01 LH7 A 1 G117 A120 K121 G125 K128 E148 I194 F226 M227 G22 A25 K26 G30 K33 E53 I99 F131 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qp5 A 1.90 BS01 LFY A 1 V115 G117 A120 K121 S122 G123 G125 E148 I194 M227 V20 G22 A25 K26 S27 G28 G30 E53 I99 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qp6 A 1.65 BS01 LJM A 1 G117 A120 K121 G123 G125 E148 I194 F226 M227 G22 A25 K26 G28 G30 E53 I99 F131 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qp7 A 1.88 BS01 LJJ A 1 V115 Q116 G117 F126 K128 E148 I194 M227 V20 Q21 G22 F31 K33 E53 I99 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qp8 A 1.64 BS01 LFG A 1 V115 G117 K128 E148 I194 M227 V20 G22 K33 E53 I99 M132 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 5qpb A 1.68 BS01 LJA A 1 T99 K128 I167 Q170 A172 F226 M227 F231 T4 K33 I72 Q75 A77 F131 M132 F136 3.6.1.62 GVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFG 6d9f A 2.03 BS01 FE A 1 E114 E180 E212 H215 E110 E176 E208 H211 IPAETGWDSAPGLLEGAMTLDLTPEQCDLGYWLRGVAQGTLAGRAETGHTDAEPTPEHMRADGPLRDAQVLELSCRSVAEAQATRVLAHYVAQAPDIVELEFFTTQLVDEARHSMVFRRHLLAMGVPADRLHASIAEVSAEYRREVLEPILDFALTTVRDEGDFVGGVAVFTIIIEGVLAPAAELSERKWNLLDPAAGAIARGAAIDEVRHLTVGSSVVRRHLLRRPERKAALLDIVRRGREIWDGIPDRKHVLRREELFQAGMREHADLLAGYEVWPGQPLLSTTPEQRYAMAEQWTDRMAAARLVHMGLPEAIDLLRLT 6d9f A 2.03 BS02 FE A 2 E84 E114 H117 E212 E80 E110 H113 E208 IPAETGWDSAPGLLEGAMTLDLTPEQCDLGYWLRGVAQGTLAGRAETGHTDAEPTPEHMRADGPLRDAQVLELSCRSVAEAQATRVLAHYVAQAPDIVELEFFTTQLVDEARHSMVFRRHLLAMGVPADRLHASIAEVSAEYRREVLEPILDFALTTVRDEGDFVGGVAVFTIIIEGVLAPAAELSERKWNLLDPAAGAIARGAAIDEVRHLTVGSSVVRRHLLRRPERKAALLDIVRRGREIWDGIPDRKHVLRREELFQAGMREHADLLAGYEVWPGQPLLSTTPEQRYAMAEQWTDRMAAARLVHMGLPEAIDLLRLT 6d9t A 2.00 BS01 UDP A 1 G12 G13 V202 S203 N204 K209 G233 K259 Q260 V263 L284 T285 E288 G15 G16 V205 S206 N207 K212 G236 K262 Q263 V266 L287 T288 E291 2.4.1.57 QGHMKIGITCYPSMGGSGIIATELGIKLAERGHEVHFITSNIPFRIRKPLPNMIFHQVEVNQYAVFQYPPYDITLSTKIAEVIKEYDLDLLHMHYAVPHAICGILAREMSGKDIKIMTTLHGTDITVLGYDHSLQGAIKFGIEKSDIVTSVSKSLAQETHEIIETNKEIIPIYNFVRENEFPTKHNTALKSQFGIAPDEKVLIHVSNFRQVKRIDTIIETFAKVREKIPSKLILLGDGPELVPMRQLTKELNVEEDVLFLGKQDCVSEFYQLSDLVLLLSEKESFGLTLLEAMKTGVVPIGSNAGGIKEVIKHGETGFVVDVGDCDSASDYAIRLLEDKVLYNKLQKNMLADIAERFGSELITDQYEYYYQKMLNE 6d9t A 2.00 BS02 UDP A 2 G12 G13 V202 K209 G233 K259 Q260 V263 L284 T285 E288 G15 G16 V205 K212 G236 K262 Q263 V266 L287 T288 E291 2.4.1.57 QGHMKIGITCYPSMGGSGIIATELGIKLAERGHEVHFITSNIPFRIRKPLPNMIFHQVEVNQYAVFQYPPYDITLSTKIAEVIKEYDLDLLHMHYAVPHAICGILAREMSGKDIKIMTTLHGTDITVLGYDHSLQGAIKFGIEKSDIVTSVSKSLAQETHEIIETNKEIIPIYNFVRENEFPTKHNTALKSQFGIAPDEKVLIHVSNFRQVKRIDTIIETFAKVREKIPSKLILLGDGPELVPMRQLTKELNVEEDVLFLGKQDCVSEFYQLSDLVLLLSEKESFGLTLLEAMKTGVVPIGSNAGGIKEVIKHGETGFVVDVGDCDSASDYAIRLLEDKVLYNKLQKNMLADIAERFGSELITDQYEYYYQKMLNE 6dbh A 2.60 BS01 G3S A 1 F264 H266 I281 G284 C285 R288 S289 A292 I326 L330 L333 V339 I341 S342 M348 L353 K367 F60 H62 I77 G80 C81 R84 S85 A88 I122 L126 L129 V135 I137 S138 M144 L149 K163 NPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKD 6dbh B 2.60 BS01 G3S B 1 K263 I281 G284 C285 R288 S289 A292 I326 M329 L330 L333 I341 S342 M364 K367 K56 I69 G72 C73 R76 S77 A80 I114 M117 L118 L121 I129 S130 M152 K155 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTDKSPFVIYDMNSLMMGEDKIKFKHITPKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETLHPLLQEIYK 6dd0 A 1.50 BS03 P9T A 1 F61 W87 H118 D120 H196 C221 R228 N233 H263 F31 W56 H85 D87 H148 C167 R174 N179 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 6dd1 A 1.70 BS03 M3Q A 1 F61 W87 H116 H118 D120 H196 N233 H263 F31 W56 H83 H85 D87 H148 N179 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 6dd1 A 1.70 BS04 M3Q A 2 Y67 H196 R228 G232 N233 H263 Y36 H148 R174 G178 N179 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 6dig A 2.00 BS01 III C 1 C11 N14 Y25 H27 Q34 F54 G55 G56 F57 N65 V68 N72 I75 M76 R79 C10 N13 Y24 H26 Q33 F53 G54 G55 F56 N64 V67 N71 I74 M75 R78 DIVADHVASCGVNLYQFYGPSGQYTHEFDGDEQFYVDLERKETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDQPLLKHWEP 6dig B 2.00 BS01 III C 1 F11 Y30 Y37 Y47 P56 D57 Y60 W61 V67 E74 T77 V78 H81 N82 A86 F9 Y28 Y35 Y45 P54 D55 Y58 W59 V65 E72 T75 V76 H79 N80 A84 SPEDFVFQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRRVEPTVTISPSNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 6dk9 A 2.60 BS01 ZN A 1 H55 H88 D89 H59 H92 D93 SPEFMSQYGFVRVPREVEKAIPVVNAPRPRAVVPPPNSETARLVREYAAKELTAPVLNHSLRVFQYSVAIIRDQFPAWDLDQEVLYVTCLLHDIATTDKNMRATKMSFEYYGGILSRELVFNATGGNQDYADAVTEAIIRHQDLTGTGYITTLGLILQIATTLDNVGSNTDLIHIDTVSAINEQFPRLHWLSCFATVVDTENSRKPWGHTSSLGDDFSKKVICNTFGYT 6dka A 2.90 BS02 CNN A 1 H88 D89 F104 H137 Q138 V157 N161 F190 H92 D93 F108 H141 Q142 V161 N165 F194 SPEFMSQYGFVRVPREVEKAIPVVNAPRPRAVVPPPNSETARLVREYAAKELTAPVLNHSLRVFQYSVAIIRDQFPAWDLDQEVLYVTCLLHDIATTDKNMRATKMSFEYYGGILSRELVFNATGGNQDYADAVTEAIIRHQDLTGTGYITTLGLILQIAVTLDNVGSNTDLIHIDTVSAINEQFPRLHWLSCFATVVDTENSRKPWGHTSSLGDDFSKKVICNTFGYTK 6dka B 2.90 BS02 CNN B 1 D89 F104 H137 Q138 V157 N161 F190 D93 F108 H141 Q142 V161 N165 F194 SPEFMSQYGFVRVPREVEKAIPVVNAPRPRAVVPPPNSETARLVREYAAKELTAPVLNHSLRVFQYSVAIIRDQFPAWDLDQEVLYVTCLLHDIATTDKNMRATKMSFEYYGGILSRELVFNATGGNQDYADAVTEAIIRHQDLTGTGYITTLGLILQIAVTLDNVGSNTDLIHIDTVSAINEQFPRLHWLSCFATVVDTENSRKPWGHTSSLGDDFSKKVICNTFGYTK 6dkc F 2.90 BS01 ZN F 1 H55 H88 D89 V157 H62 H95 D96 V164 4.2.1.69 PLGSPEFMSQYGFVRVPREVEKAIPVVNAPRPRAVVPPPNSETARLVREYAAKELTAPVLNHSLRVFQYSVAIIRDQFPAWDLDQEVLYVTCLLHDIATTDKNMRATKMSFEYYGGILSRELVFNATGGNQDYADAVTEAIIRHQDLTGTGYITTLGLILQIAVTLDNVGSNTDLIHIDTVSAINEQFPRLHWLSCFATVVDTENSRKPWGHTSSLGDDFSKKVICNTFGYT 6dl7 A 2.00 BS01 ONC A 1 L79 E82 H116 Y118 W146 L170 L13 E16 H50 Y52 W80 L104 3.4.21.92 SLIPIVVDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVH 6dl7 C 2.00 BS02 ONC D 1 L104 S108 T135 Y138 L38 S42 T69 Y72 3.4.21.92 SLIPIVVDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSGATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPP 6dl7 D 2.00 BS01 ONC D 1 L79 E82 I84 H116 Y118 W146 L170 L13 E16 I18 H50 Y52 W80 L104 3.4.21.92 SLIPIVVDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPP 6dl7 E 2.00 BS01 ONC E 1 L79 E82 H116 Y118 W146 L13 E16 H50 Y52 W80 3.4.21.92 SLIPIVVDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSGGATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQ 6dl7 E 2.00 BS02 ONC F 1 I100 L104 S108 T135 Y138 I34 L38 S42 T69 Y72 3.4.21.92 SLIPIVVDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSGGATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQ 6dl7 F 2.00 BS01 ONC F 1 L79 E82 I84 H116 Y118 W146 V148 L170 L13 E16 I18 H50 Y52 W80 V82 L104 3.4.21.92 SLIPIVVDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPP 6dl7 G 2.00 BS01 ONC A 1 I100 L104 F105 S108 T135 Y138 I35 L39 F40 S43 T70 Y73 3.4.21.92 SLIPIVVYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQ 6dl7 G 2.00 BS02 ONC G 1 L79 E82 I84 H116 Y118 W146 V148 L14 E17 I19 H51 Y53 W81 V83 3.4.21.92 SLIPIVVYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQ 6e1j A 2.10 BS01 MN A 1 D90 H288 H290 N324 D27 H225 H227 N261 31023839 VERWPEYIPNKLPDKNYVRVFDTTLRDGEQSPGAALTPPQKIEIARQLAKLRVDIMEVGFPVSSEEEFETIQTIAKTVGNEVDEETGYIPVICVIARSKERDIKAAWESVKYAKRPRIVIFTSTSDIHLKYKLKMTREEVVDMVASSIRFAKSLGFEDIEFGCEDGGRSDKDYICTVFEEAIKAGATTLACPDTVGINMPHEYGKLVRYIKANTPGIDDVIFSAHCHNDLGVATANTIAGICAGARQVEVTINGIGERSGNAPLEEVVMALKCRGAFVMGGVYTRIDTRQIMATSKMVQEYTGLYVQPHKPIVGANCFVHESGIHQDGILKNRSTYEIISPEDVGVVKSQNSGIVLGKLSGRHAVKGRLKELGYEISDEKLNEVFSRFRDLTKQKKRVTDDDLKALVTC 6e1j A 2.10 BS02 MN A 2 V145 E147 V82 E84 31023839 VERWPEYIPNKLPDKNYVRVFDTTLRDGEQSPGAALTPPQKIEIARQLAKLRVDIMEVGFPVSSEEEFETIQTIAKTVGNEVDEETGYIPVICVIARSKERDIKAAWESVKYAKRPRIVIFTSTSDIHLKYKLKMTREEVVDMVASSIRFAKSLGFEDIEFGCEDGGRSDKDYICTVFEEAIKAGATTLACPDTVGINMPHEYGKLVRYIKANTPGIDDVIFSAHCHNDLGVATANTIAGICAGARQVEVTINGIGERSGNAPLEEVVMALKCRGAFVMGGVYTRIDTRQIMATSKMVQEYTGLYVQPHKPIVGANCFVHESGIHQDGILKNRSTYEIISPEDVGVVKSQNSGIVLGKLSGRHAVKGRLKELGYEISDEKLNEVFSRFRDLTKQKKRVTDDDLKALVTC 6e1j A 2.10 BS03 KMT A 1 R89 D90 V182 E223 E227 A253 P255 T257 H288 H290 R26 D27 V119 E160 E164 A190 P192 T194 H225 H227 31023839 VERWPEYIPNKLPDKNYVRVFDTTLRDGEQSPGAALTPPQKIEIARQLAKLRVDIMEVGFPVSSEEEFETIQTIAKTVGNEVDEETGYIPVICVIARSKERDIKAAWESVKYAKRPRIVIFTSTSDIHLKYKLKMTREEVVDMVASSIRFAKSLGFEDIEFGCEDGGRSDKDYICTVFEEAIKAGATTLACPDTVGINMPHEYGKLVRYIKANTPGIDDVIFSAHCHNDLGVATANTIAGICAGARQVEVTINGIGERSGNAPLEEVVMALKCRGAFVMGGVYTRIDTRQIMATSKMVQEYTGLYVQPHKPIVGANCFVHESGIHQDGILKNRSTYEIISPEDVGVVKSQNSGIVLGKLSGRHAVKGRLKELGYEISDEKLNEVFSRFRDLTKQKKRVTDDDLKALVTC 6e1j A 2.10 BS04 COA A 1 S385 G386 I387 D390 K394 L422 R425 H426 R452 S322 G323 I324 D327 K331 L359 R362 H363 R389 31023839 VERWPEYIPNKLPDKNYVRVFDTTLRDGEQSPGAALTPPQKIEIARQLAKLRVDIMEVGFPVSSEEEFETIQTIAKTVGNEVDEETGYIPVICVIARSKERDIKAAWESVKYAKRPRIVIFTSTSDIHLKYKLKMTREEVVDMVASSIRFAKSLGFEDIEFGCEDGGRSDKDYICTVFEEAIKAGATTLACPDTVGINMPHEYGKLVRYIKANTPGIDDVIFSAHCHNDLGVATANTIAGICAGARQVEVTINGIGERSGNAPLEEVVMALKCRGAFVMGGVYTRIDTRQIMATSKMVQEYTGLYVQPHKPIVGANCFVHESGIHQDGILKNRSTYEIISPEDVGVVKSQNSGIVLGKLSGRHAVKGRLKELGYEISDEKLNEVFSRFRDLTKQKKRVTDDDLKALVTC 6e1j A 2.10 BS05 COA B 1 Q93 F123 S126 I158 R160 S161 F184 T185 K195 L196 Q30 F60 S63 I95 R97 S98 F121 T122 K132 L133 31023839 VERWPEYIPNKLPDKNYVRVFDTTLRDGEQSPGAALTPPQKIEIARQLAKLRVDIMEVGFPVSSEEEFETIQTIAKTVGNEVDEETGYIPVICVIARSKERDIKAAWESVKYAKRPRIVIFTSTSDIHLKYKLKMTREEVVDMVASSIRFAKSLGFEDIEFGCEDGGRSDKDYICTVFEEAIKAGATTLACPDTVGINMPHEYGKLVRYIKANTPGIDDVIFSAHCHNDLGVATANTIAGICAGARQVEVTINGIGERSGNAPLEEVVMALKCRGAFVMGGVYTRIDTRQIMATSKMVQEYTGLYVQPHKPIVGANCFVHESGIHQDGILKNRSTYEIISPEDVGVVKSQNSGIVLGKLSGRHAVKGRLKELGYEISDEKLNEVFSRFRDLTKQKKRVTDDDLKALVTC 6e1j B 2.10 BS01 COA A 1 R89 Q93 F123 S126 R160 S161 K162 F184 T185 K195 L196 R25 Q29 F59 S62 R96 S97 K98 F120 T121 K131 L132 31023839 ERWPEYIPNKLPDKNYVRVFDTTLRDGEQSPGAALTPPQKIEIARQLAKLRVDIMEVGFPVSSEEEFETIQTIAKTVGNEVDEETGYIPVICVIARSKERDIKAAWESVKYAKRPRIVIFTSTSDIHLKYKLKMTREEVVDMVASSIRFAKSLGFEDIEFGCEDGGRSDKDYICTVFEEAIKAGATTLACPDTVGINMPHEYGKLVRYIKANTPGIDDVIFSAHCHNDLGVATANTIAGICAGARQVEVTINGIGERSGNAPLEEVVMALKCRGAFVMGGVYTRIDTRQIMATSKMVQEYTGLYVQPHKPIVGANCFVHESGIHQDGILKNRSTYEIISPEDVGVVKSQNSGIVLGKLSGRHAVKGRLKELGYEISDEKLNEVFSRFRDLTKQKKRVTDDDLKALVTC 6e1j B 2.10 BS03 KMT B 1 R89 D90 I158 E227 P255 T257 H288 H290 R25 D26 I94 E163 P191 T193 H224 H226 31023839 ERWPEYIPNKLPDKNYVRVFDTTLRDGEQSPGAALTPPQKIEIARQLAKLRVDIMEVGFPVSSEEEFETIQTIAKTVGNEVDEETGYIPVICVIARSKERDIKAAWESVKYAKRPRIVIFTSTSDIHLKYKLKMTREEVVDMVASSIRFAKSLGFEDIEFGCEDGGRSDKDYICTVFEEAIKAGATTLACPDTVGINMPHEYGKLVRYIKANTPGIDDVIFSAHCHNDLGVATANTIAGICAGARQVEVTINGIGERSGNAPLEEVVMALKCRGAFVMGGVYTRIDTRQIMATSKMVQEYTGLYVQPHKPIVGANCFVHESGIHQDGILKNRSTYEIISPEDVGVVKSQNSGIVLGKLSGRHAVKGRLKELGYEISDEKLNEVFSRFRDLTKQKKRVTDDDLKALVTC 6e1j B 2.10 BS04 COA B 1 S385 G386 I387 D390 K394 L422 G424 R425 H426 R452 S321 G322 I323 D326 K330 L358 G360 R361 H362 R388 31023839 ERWPEYIPNKLPDKNYVRVFDTTLRDGEQSPGAALTPPQKIEIARQLAKLRVDIMEVGFPVSSEEEFETIQTIAKTVGNEVDEETGYIPVICVIARSKERDIKAAWESVKYAKRPRIVIFTSTSDIHLKYKLKMTREEVVDMVASSIRFAKSLGFEDIEFGCEDGGRSDKDYICTVFEEAIKAGATTLACPDTVGINMPHEYGKLVRYIKANTPGIDDVIFSAHCHNDLGVATANTIAGICAGARQVEVTINGIGERSGNAPLEEVVMALKCRGAFVMGGVYTRIDTRQIMATSKMVQEYTGLYVQPHKPIVGANCFVHESGIHQDGILKNRSTYEIISPEDVGVVKSQNSGIVLGKLSGRHAVKGRLKELGYEISDEKLNEVFSRFRDLTKQKKRVTDDDLKALVTC 6gdv A 2.00 BS01 BTB A 1 C41 Y104 W107 C36 Y99 W102 SLIETADLRLLLTTVSTEVEAQQLAQAAVEAGLAACVSITPIQSCYRWQGAIARETEQQMSFKTTVEQLDALQQWLQSQHPYALPECLVLTPIASSVAYRDWLRSSLS 6gdv C 2.00 BS01 BTB A 1 Y51 E62 Y87 L89 E91 Y49 E60 Y85 L87 E89 DLSSLIETADLRLLLTTVSTEVEAQQLAQAAVEAGLAACVSITPIQSCYRWQGAIARETEQQMSFKTTVEQLDALQQWLQSQHPYALPECLVLTPIASSVAYRDWLRSSL 6gdw A 1.80 BS01 BTB A 1 Y51 W53 E62 Y87 L89 Y47 W49 E58 Y83 L85 SSLIETADLRLLLTTVSTEVEAQQLAQAAVEAGLAACVSITPIQSCYRWQGAIARETEQQMSFKTTVEQLDALQQWLQSQHPYALPECLVLTPIASSVAYRDWLRSSL 6gdw C 1.80 BS01 BTB C 1 T19 Y51 W53 Y87 L89 E91 T17 Y49 W51 Y85 L87 E89 DLSSLIETADLRLLLTTVSTEVEAQQLAQAAVEAGLAACVSITPIQSCYRWQGAIARETEQQMSFKTTVEQLDALQQWLQSQHPYALPECLVLTPIASSVAYRDWLRSSL 6gdx A 1.17 BS01 BTB A 1 Y51 W53 E62 Y87 L89 P90 E91 Y46 W48 E57 Y82 L84 P85 E86 SLIETADLRLLLTTVSTEVEAQQLAQAAVEAGLAACVSITPIQSCYRWQGAIARETEQQMSFKTTVEQLDALQQWLQSQHPYALPECLVLTPIASSVAYRDWLRSSL 6gdx B 1.17 BS01 BTB B 1 Y51 W53 E62 Y87 L89 P90 Y47 W49 E58 Y83 L85 P86 SSLIETADLRLLLTTVSTEVEAQQLAQAAVEAGLAACVSITPIQSCYRWQGAIARETEQQMSFKTTVEQLDALQQWLQSQHPYALPECLVLTPIASSVAYRDWLRSSL 6gdx C 1.17 BS02 BTB C 1 Y51 W53 E62 L89 P90 E91 Y46 W48 E57 L84 P85 E86 SLIETADLRLLLTTVSTEVEAQQLAQAAVEAGLAACVSITPIQSCYRWQGAIARETEQQMSFKTTVEQLDALQQWLQSQHPYALPECLVLTPIASSVAYRDWLRSSLS 6ge8 A 1.87 BS01 EWE A 1 Y25 W64 G124 S125 Y157 H158 G159 E220 D254 I256 A257 K283 Y19 W58 G118 S119 Y151 H152 G153 E208 D242 I244 A245 K271 2.6.1.62 GLTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVG 6ge8 B 1.87 BS02 EWE B 1 Y25 W64 G124 S125 Y157 H158 G159 E220 A226 D254 I256 A257 K283 F402 Y19 W58 G118 S119 Y151 H152 G153 E206 A212 D240 I242 A243 K269 F388 2.6.1.62 GLTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVG 6ge8 B 1.87 BS03 MG B 1 Y157 H158 G159 A164 M165 C168 Y151 H152 G153 A158 M159 C162 2.6.1.62 GLTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVG 6gem A 3.46 BS02 AKG A 1 R153 H164 S189 F252 H259 R270 T272 R143 H154 S179 F242 H249 R260 T262 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSELPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVESKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRNKIYYWS 6gem B 3.46 BS01 FE B 1 H164 S189 H259 F276 H154 S179 H249 F266 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSELPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVESKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRNKIYYWS 6gem C 3.46 BS02 AKG C 1 R153 I161 H164 S189 F252 H259 R270 T272 R143 I151 H154 S179 F242 H249 R260 T262 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSELPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVESKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRNKIYYWS 6gem D 3.46 BS02 AKG D 1 R153 I161 H164 S189 H259 R270 T272 R143 I151 H154 S179 H249 R260 T262 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSELPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVESKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRNKIYYWS 6gf3 B 2.40 BS02 EX5 B 1 V238 C241 L248 A250 K254 L255 N258 M259 T314 A316 I318 N349 N350 K352 A354 I378 V235 C238 L245 A247 K251 L252 N255 M256 T305 A307 I309 N340 N341 K343 A345 I361 30006510 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 6gf3 F 2.40 BS01 ACP F 1 I148 Q183 K184 Y185 L186 K198 R222 D318 M320 E331 N333 I113 Q120 K121 Y122 L123 K135 R159 D234 M236 E247 N249 30006510 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPDEREVFGNVWIAKSHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKL 6gfa A 2.00 BS01 MG A 1 N179 N366 A370 R373 N178 N365 A369 R372 VVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTLNADEAVARGCALQC 6gfa A 2.00 BS02 ATP A 1 G8 S9 Q10 S11 K67 G203 H204 S205 G232 E270 K273 K274 S277 G341 G342 A343 R345 I346 G7 S8 Q9 S10 K66 G202 H203 S204 G231 E269 K272 K273 S276 G340 G341 A342 R344 I345 VVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTLNADEAVARGCALQC 6gfo E 2.10 BS01 NAD D 1 D66 Y73 D66 Y73 MSNLEKQIEQAREEAHKICDTEGATSGQCAAAWDALEELQAEAAHQRAEQQDHKTSFQQYCDDNPDAAECRIYDD 6gfp B 1.54 BS02 NAD B 1 G8 F9 G10 R11 I12 N35 D36 T37 R81 A99 T100 G101 T123 A124 C154 T184 N317 Y321 G9 F10 G11 R12 I13 N36 D37 T38 R82 A100 T101 G102 T124 A125 C155 T185 N318 Y322 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6gfq A 1.40 BS02 MG A 1 G305 N307 G306 N308 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6gfq B 1.40 BS01 III C 1 R81 V102 P125 S153 T155 H181 T184 G185 D186 R188 S193 H194 R195 R199 T212 G213 A214 R235 R82 V103 P126 S154 T156 H182 T185 G186 D187 R189 S194 H195 R196 R200 T213 G214 A215 R236 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6gg7 B 1.32 BS01 III C 1 R81 V102 S153 T155 H181 T184 G185 D186 R188 S193 H194 R195 D196 R199 T212 G213 R235 R82 V103 S154 T156 H182 T185 G186 D187 R189 S194 H195 R196 D197 R200 T213 G214 R236 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6gg7 B 1.32 BS02 III D 1 T37 S38 D39 S79 R81 R188 T38 S39 D40 S80 R82 R189 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6gg7 A 1.32 BS01 III C 1 T37 S38 S79 R81 T38 S39 S80 R82 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6ghl A 2.38 BS01 III E 1 T37 S38 D39 S79 R81 T38 S39 D40 S80 R82 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6ghl B 2.38 BS01 NAD B 1 G8 F9 G10 R11 I12 N35 D36 T37 R81 A99 T100 G101 F103 T123 A124 C154 T184 N317 E318 Y321 G9 F10 G11 R12 I13 N36 D37 T38 R82 A100 T101 G102 F104 T124 A125 C155 T185 N318 E319 Y322 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6ghl D 2.38 BS01 III E 1 R81 V102 P125 S153 C154 T155 H181 G185 D186 R188 S193 H194 R195 R199 T212 A233 R235 R83 V104 P127 S155 C156 T157 H183 G187 D188 R190 S195 H196 R197 R201 T214 A235 R237 1.2.1.- GSMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6ghr B 2.25 BS01 NAD B 1 G8 F9 G10 R11 I12 N35 D36 T37 R81 A99 T100 G101 F103 T123 C154 T184 N317 Y321 G13 F14 G15 R16 I17 N40 D41 T42 R86 A104 T105 G106 F108 T128 C159 T189 N322 Y326 1.2.1.- VPRGSMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6ghr C 2.25 BS01 NAD C 1 G8 G10 R11 I12 N35 D36 T37 R81 A99 T100 G101 F103 T123 A124 C154 N317 Y321 G9 G11 R12 I13 N36 D37 T38 R82 A100 T101 G102 F104 T124 A125 C155 N318 Y322 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6ghr D 2.25 BS02 NAD D 1 G8 G10 R11 I12 N35 D36 T37 R81 A99 T100 G101 T123 A124 C154 T184 N317 Y321 G9 G11 R12 I13 N36 D37 T38 R82 A100 T101 G102 T124 A125 C155 T185 N318 Y322 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6ghr A 2.25 BS01 III E 1 R81 V102 S153 C154 T155 H181 T184 G185 D186 R188 S193 H194 R195 R199 T212 G213 A214 R235 R82 V103 S154 C155 T156 H182 T185 G186 D187 R189 S194 H195 R196 R200 T213 G214 A215 R236 1.2.1.- SMVRVAINGFGRIGRNFMRCWLQRKANSKLEIVGINDTSDPRTNAHLLKYDSMLGIFQDAEITADDDCIYAGGHAVKCVSDRNPENLPWSAWGIDLVIEATGVFTSREGASKHLSAGAKKVLITAPGKGNIPTYVVGVNHHTYDPSEDIVSNASCTTNCLAPIVKVLHEAFGIQQGMMTTTHSYTGDQRLLDASHRDLRRARAAAMNIVPTSTGAAKAVGLVIPELQGKLNGIALRVPTPNVSVVDFVAQVEKPTIAEQVNQVIKEASETTMKGIIHYSELELVSSDYRGHNASSILDASLTMVLGGNLVKVVAWYDNEWGYSQRVLDLAEHMAAHWA 6gwi A 2.00 BS01 PLP A 1 S115 G116 S117 N120 Y149 H150 G151 E222 D255 V257 I258 K284 S114 G115 S116 N119 Y148 H149 G150 E221 D254 V256 I257 K283 2.6.1.- QTQDYQALDRAHHLHPFTDFKALGEEGSRVVTHAEGVYIHDSEGNRILDGMAGLWCVNLGYGRRELVEAATAQLEQLPYYNTFFKTTHPPAVRLAEKLCDLAPAHINRVFFTGSGSEANDTVLRMVRRYWALKGQPDKQWIIGRENAYHGSTLAGMSLGGMAPMHAQGGPCVPGIAHIRQPYWFGEGRDMSPEAFGQTCAEALEEKILELGEEKVAAFIAEPVQGAGGAIMPPESYWPAVKKVLAKYDILLVADEVICGFGRLGEWFGSQHYGLEPDLMPIAKGLSSGYLPIGGVLVGDRVAETLIEEGGEFFHGFTYSGHPTCAAVALKNLELLEAEGVVDRVRDDLGPYLAERWASLVDHPIVGEARSLGLMGALELVADKTTGQRFDKSLGAGNLCRDLCFANGLVMRSVGDTMIISPPLVIRREEIDELVELARRALDETARQLT 6gwi A 2.00 BS02 PLP B 1 F317 T318 F316 T317 2.6.1.- QTQDYQALDRAHHLHPFTDFKALGEEGSRVVTHAEGVYIHDSEGNRILDGMAGLWCVNLGYGRRELVEAATAQLEQLPYYNTFFKTTHPPAVRLAEKLCDLAPAHINRVFFTGSGSEANDTVLRMVRRYWALKGQPDKQWIIGRENAYHGSTLAGMSLGGMAPMHAQGGPCVPGIAHIRQPYWFGEGRDMSPEAFGQTCAEALEEKILELGEEKVAAFIAEPVQGAGGAIMPPESYWPAVKKVLAKYDILLVADEVICGFGRLGEWFGSQHYGLEPDLMPIAKGLSSGYLPIGGVLVGDRVAETLIEEGGEFFHGFTYSGHPTCAAVALKNLELLEAEGVVDRVRDDLGPYLAERWASLVDHPIVGEARSLGLMGALELVADKTTGQRFDKSLGAGNLCRDLCFANGLVMRSVGDTMIISPPLVIRREEIDELVELARRALDETARQLT 6gxb A 1.35 BS02 FF5 A 1 L57 Q67 F70 D71 D72 S73 L91 Q92 H94 H96 H119 V121 V130 V142 L197 T198 T199 W208 L54 Q64 F67 D68 D69 S70 L88 Q89 H91 H93 H116 V118 V127 V139 L194 T195 T196 W205 4.2.1.1 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 6gxk A 1.70 BS01 NAP A 1 G22 T23 Y24 D50 Y55 K84 H117 S166 N167 Q190 Y216 S217 L219 G220 S221 Q222 L236 A253 L268 A269 K270 S271 Y272 R276 Q279 N280 G17 T18 Y19 D45 Y50 K79 H112 S161 N162 Q185 Y211 S212 L214 G215 S216 Q217 L231 A248 L263 A264 K265 S266 Y267 R271 Q274 N275 1.-.-.-,1.1.1.357,1.1.1.112,1.1.1.188,1.1.1.239,1.1.1.64 QCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSDEY 6gxk A 1.70 BS02 FFW A 1 Y24 L54 Y55 W86 H117 M120 N167 Y216 S217 Y305 F306 S308 Y317 Y319 Y19 L49 Y50 W81 H112 M115 N162 Y211 S212 Y300 F301 S303 Y312 Y314 1.-.-.-,1.1.1.357,1.1.1.112,1.1.1.188,1.1.1.239,1.1.1.64 QCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSDEY 6hnc A 1.50 BS02 1CY A 1 R14 S95 F97 Y174 L209 W221 R13 S94 F96 Y155 L190 W202 31012301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6hnc B 1.50 BS02 1CY B 1 R14 S95 F97 Y174 L209 P210 W221 R13 S94 F96 Y155 L190 P191 W202 31012301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6hnc C 1.50 BS01 NAP C 1 R14 I15 H33 Y34 H35 N36 S37 D62 L63 T64 N93 A94 S95 T126 L159 C160 Y174 K178 P204 G205 V206 S207 L208 R12 I13 H31 Y32 H33 N34 S35 D60 L61 T62 N91 A92 S93 T114 L138 C139 Y153 K157 P183 G184 V185 S186 L187 31012301 APAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6hnr A 1.58 BS02 GFE A 1 R14 S95 F97 Y174 V206 L209 M213 W221 R13 S94 F96 Y155 V187 L190 M194 W202 31012301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6hnr C 1.58 BS02 GFE C 1 R14 S95 F97 Y174 V206 P210 W221 R12 S93 F95 Y154 V186 P190 W201 31012301 APAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6hnr D 1.58 BS02 GFE D 1 R14 S95 F97 Y174 V206 L209 W221 R13 S94 F96 Y155 V187 L190 W202 31012301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6how A 1.92 BS02 GJQ A 1 R14 S95 F97 Y174 S207 L209 P210 R13 S94 F96 Y154 S187 L189 P190 31012301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6how B 1.92 BS02 GJQ B 1 R14 S95 F97 Y174 S207 L208 L209 P210 A212 R13 S94 F96 Y154 S187 L188 L189 P190 A192 31012301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6how D 1.92 BS02 GJQ D 1 R14 S95 F97 Y174 S207 L208 L209 P210 R13 S94 F96 Y154 S187 L188 L189 P190 31012301 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6i41 A 1.90 BS01 III B 1 L76 Y87 Y123 K129 D130 W131 G132 F133 K134 L49 Y60 Y96 K102 D103 W104 G105 F106 K107 31026449 SGKVVKFSYMWTINNFSFCREGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQD 6i5p A 1.81 BS01 III B 1 L76 Y87 F102 Y123 K129 D130 W131 G132 F133 K134 L48 Y59 F74 Y95 K101 D102 W103 G104 F105 K106 31026449 VVKFSYMWTINNFSFCREKMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVV 6i5p G 1.81 BS01 III H 1 Y87 Y123 K129 D130 W131 G132 F133 K134 Y61 Y97 K103 D104 W105 G106 F107 K108 31026449 GKVVKFSYMWTINNFSFCREKMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQD 6i68 C 1.85 BS01 III D 1 L76 Y87 Y123 G128 K129 D130 W131 G132 F133 K134 L49 Y60 Y96 G101 K102 D103 W104 G105 F106 K107 31026449 KVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAVESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQD 6i7a G 2.20 BS01 III H 1 Y87 F102 Y123 K129 D130 W131 G132 F133 K134 Y58 F73 Y94 K100 D101 W102 G103 F104 K105 31026449 VVKFSYMWTINNFSFCREMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRNFLLDEANGLLPDDKLTLFCEVSVVQD 6mm5 E 1.95 BS01 III C 1 Q84 E127 F129 R133 D166 K168 P169 E170 F187 T197 L198 C199 G200 T201 E203 Y204 E230 P236 F239 Q72 E115 F117 R121 D154 K156 P157 E158 F175 T185 L186 C187 G188 T189 E191 Y192 E218 P224 F227 2.7.11.11 NAVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 6mm5 E 1.95 BS03 ANP E 1 L49 G50 T51 G52 V57 A70 K72 V104 M120 E121 Y122 V123 E127 K168 E170 N171 L173 T183 D184 F327 L37 G38 T39 G40 V45 A58 K60 V92 M108 E109 Y110 V111 E115 K156 E158 N159 L161 T171 D172 F315 2.7.11.11 NAVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 6mm6 C 2.39 BS01 ANP C 1 T51 G52 S53 V57 A70 E121 Y122 V123 T34 G35 S36 V40 A53 E104 Y105 V106 2.7.11.11 FLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFYEEEEIRVSINEKCGKEFTEF 6mm6 E 2.39 BS01 ANP E 1 T51 G52 S53 V57 A70 K72 E121 Y122 V123 D184 T34 G35 S36 V40 A53 K55 E104 Y105 V106 D167 2.7.11.11 FLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFEEEIRVSINEKCGKEFTEF 6mm7 A 1.85 BS01 ANP A 1 L49 T51 G52 S53 V57 A70 K72 E121 Y122 V123 L34 T36 G37 S38 V42 A55 K57 E106 Y107 V108 2.7.11.11 KEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFFDDYEEEEIRVSINEKCGKEFTEF 6mm7 D 1.85 BS01 ANP D 1 G50 T51 G52 V57 A70 K72 E121 Y122 V123 D184 G36 T37 G38 V43 A56 K58 E107 Y108 V109 D170 2.7.11.11 VKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKYEEEEIRVSINEKCGKEFTEF 6mm8 C 1.85 BS01 ANP C 1 G50 G52 S53 V57 A70 K72 E121 Y122 V123 G37 G39 S40 V44 A57 K59 E108 Y109 V110 2.7.11.11 AVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFYEEEEIRVSINEKCGKEFTEF 6mue A 1.90 BS01 III B 1 E85 E88 F93 M110 M145 M146 E79 E82 F87 M104 M136 M137 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 6n4o A 2.90 BS01 NUC C 1 K65 P67 R68 R126 A221 T222 I269 R277 Y279 R280 F294 Y311 F312 H316 Q332 H336 T337 Y338 L339 R351 L356 T361 M364 I365 R375 L522 G524 K525 T526 Y529 K533 Q545 C546 Q548 N551 Q558 T559 N562 L563 K566 K570 A603 G604 R635 K709 R710 R714 H753 I756 Q757 T759 S760 R761 Y790 R792 C793 R795 V797 S798 Y804 R812 K44 P46 R47 R100 A191 T192 I235 R240 Y242 R243 F257 Y267 F268 H272 Q288 H291 T292 Y293 L294 R306 L311 T316 M319 I320 R330 L477 G479 K480 T481 Y484 K488 Q500 C501 Q503 N506 Q513 T514 N517 L518 K521 K525 A558 G559 R590 K664 R665 R669 H708 I711 Q712 T714 S715 R716 Y745 R747 C748 R750 V752 S753 Y759 R767 3.1.26.- 31028083 AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQTDSQRVKFTKEIKGLKVEITHCKRKYRVCNVTRRPASHQTFPTVECTVAQYFKDRHKLVLRYPHLPCLQVGQQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRAGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 6n4o A 2.90 BS02 NUC D 1 K65 I353 K355 D358 T361 S362 I365 M437 R438 K525 Q558 S561 K726 I756 Q757 F811 R814 K44 I308 K310 D313 T316 S317 I320 M392 R393 K480 Q513 S516 K681 I711 Q712 F766 R769 3.1.26.- 31028083 AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQTDSQRVKFTKEIKGLKVEITHCKRKYRVCNVTRRPASHQTFPTVECTVAQYFKDRHKLVLRYPHLPCLQVGQQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRAGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 6nad A 2.90 BS01 KHY A 1 Q286 L287 C320 H323 L324 A327 M358 V361 R364 M365 V376 F377 F378 E379 F388 L396 I400 F401 Q22 L23 C56 H59 L60 A63 M94 V97 R100 M101 V112 F113 F114 E115 F124 L132 I136 F137 31010722 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQI 6nad B 2.90 BS01 KHY B 1 Q286 L287 C320 H323 L324 M358 R364 M365 A368 V376 F377 F378 E379 F388 L396 I400 F401 Q22 L23 C56 H59 L60 M94 R100 M101 A104 V112 F113 F114 E115 F124 L132 I136 F137 31010722 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQH 6njh A 2.15 BS02 KRD A 1 H326 M439 N487 W498 T499 F506 M523 Q535 F538 F599 I600 H73 M186 N231 W242 T243 F250 M267 Q279 F282 F327 I328 3.1.4.53 31013090 QEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPNQVSEFISNTFLD 6njh B 2.15 BS02 KRD B 1 H326 N487 W498 T499 I502 F506 M523 Q535 F538 F599 I600 H74 N232 W243 T244 I247 F251 M268 Q280 F283 F328 I329 3.1.4.53 31013090 EQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPNQVSEFISNTFLD 6njh D 2.15 BS02 KRD D 1 H326 S374 M439 N487 W498 T499 I502 M523 Q535 F538 F599 I600 H72 S120 M185 N230 W241 T242 I245 M266 Q278 F281 F326 I327 3.1.4.53 31013090 EDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPNQVSEFISNTFLD 6nji A 2.45 BS03 KR4 A 1 H326 M439 N487 W498 T499 I502 M523 Q535 F538 F599 I600 T603 H74 M187 N235 W246 T247 I250 M271 Q283 F286 F332 I333 T336 3.1.4.53 31013090 EQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQNQVSEFISNTFLD 6nji B 2.45 BS02 KR4 B 1 H326 M439 N487 T499 M503 M523 Q535 F538 F599 I600 T603 H73 M186 N231 T243 M247 M267 Q279 F282 F328 I329 T332 3.1.4.53 31013090 QEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQNQVSEFISNTFLD 6njj A 2.30 BS02 KR7 A 1 Y325 H326 M439 N487 Y495 W498 T499 I502 Q535 F538 F599 I600 T603 Y72 H73 M186 N231 Y239 W242 T243 I246 Q279 F282 F327 I328 T331 3.1.4.53 31013090 QEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPNQVSEFISNTFLD 6njj B 2.30 BS02 KR7 B 1 Y325 H326 M439 N487 Y495 W498 T499 I502 F506 M523 Q535 F538 F599 I600 T603 Y72 H73 M186 N231 Y239 W242 T243 I246 F250 M267 Q279 F282 F327 I328 T331 3.1.4.53 31013090 QEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPNQVSEFISNTFLD 6njj D 2.30 BS02 KR7 D 1 M439 N487 Y495 W498 T499 I502 Q535 F538 F599 I600 T603 M186 N231 Y239 W242 T243 I246 Q279 F282 F327 I328 T331 3.1.4.53 31013090 QEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPNQVSEFISNTFLD 6nlg A 1.50 BS01 KT7 A 1 P69 N70 L71 Q72 P69 N70 L71 Q72 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQSDLNLELCATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nlg B 1.50 BS01 KT7 A 1 L27 I79 L27 I79 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQSDLNLELCATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nlg C 1.50 BS01 KT7 C 1 L68 P69 N70 L71 Q72 L68 P69 N70 L71 Q72 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQSDLNLELCATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nli A 1.90 BS01 FE2 A 1 N148 Q151 N148 Q151 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nli B 1.90 BS04 KTM E 1 L27 I79 G80 E81 L27 I79 G80 E81 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nli E 1.90 BS04 KTM E 1 L68 P69 L71 Q72 L68 P69 L71 Q72 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nli H 1.90 BS01 KTM H 1 P69 L71 Q72 P69 L71 Q72 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nli J 1.90 BS02 KTM H 1 L27 I79 G80 L27 I79 G80 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nlj B 1.65 BS01 KTV E 1 L27 M31 I79 G80 E81 L27 M31 I79 G80 E81 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMH 6nlj F 1.65 BS01 KTV K 1 L27 M31 I79 E81 L27 M31 I79 E81 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMH 6nlk B 1.85 BS03 KTG E 1 L27 M31 W35 I79 G80 E81 L27 M31 W35 I79 G80 E81 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nlk F 1.85 BS04 KTG K 1 L27 M31 I79 G80 L27 M31 I79 G80 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nlk K 1.85 BS02 KTG F 1 L27 M31 W35 I79 L27 M31 W35 I79 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nll H 1.80 BS03 KT4 J 1 L27 M31 W35 I79 E81 L27 M31 W35 I79 E81 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMH 6nlm B 1.90 BS02 KT1 B 1 L63 L68 P69 L71 Q72 L63 L68 P69 L71 Q72 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMH 6nlm J 1.90 BS02 KT1 H 1 L27 M31 W35 I79 G80 L27 M31 W35 I79 G80 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMH 6nln A 1.60 BS03 KSY A 2 L68 N70 Q72 L68 N70 Q72 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nln C 1.60 BS04 KSY I 1 L27 W35 I79 E81 L27 W35 I79 E81 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nln F 1.60 BS02 KSY F 1 L63 L68 P69 N70 L71 Q72 L63 L68 P69 N70 L71 Q72 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6nln F 1.60 BS04 KSY K 1 L27 I79 E81 L27 I79 E81 1.16.3.1 31038945 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 6o5w A 1.41 BS01 ZN A 1 C413 C416 C435 C446 C17 C20 C39 C50 31006586 TARSKVGGSGDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPE 6oau A 2.48 BS01 CA A 1 A194 P195 R197 S199 D202 A165 P166 R168 S170 D173 3.1.1.34 QRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLN 6ob0 A 2.81 BS01 M3D A 1 W82 V84 Q262 L263 V264 K265 W53 V55 Q233 L234 V235 K236 3.1.1.34 QRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLN 6ob0 A 2.81 BS02 M3D A 2 W82 V84 Y121 P122 S159 P187 K265 H268 W53 V55 Y92 P93 S130 P158 K236 H239 3.1.1.34 QRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLN 6ob0 A 2.81 BS03 CA A 1 A194 P195 R197 L198 S199 D202 A165 P166 R168 L169 S170 D173 3.1.1.34 QRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLN 6ob0 B 2.81 BS02 M3D B 2 W82 H120 Y121 P122 S159 P187 K265 H268 W53 H91 Y92 P93 S130 P158 K236 H239 3.1.1.34 QRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLN 6ob0 C 2.81 BS01 M3D C 1 W82 V84 Q262 L263 K265 W53 V55 Q233 L234 K236 3.1.1.34 QRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLN 6ob0 D 2.81 BS02 M3D D 2 W82 Y121 S159 P187 K265 H268 W53 Y92 S130 P158 K236 H239 3.1.1.34 QRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLN 6ob0 D 2.81 BS03 CA D 1 A194 P195 R197 S199 D202 A165 P166 R168 S170 D173 3.1.1.34 QRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLN 6ocq A 2.79 BS01 M5J A 1 M67 L70 V76 M92 L129 V134 H136 I154 A155 D156 M54 L57 V63 M79 L116 V121 H123 I141 A142 D143 2.7.11.1 31013427 NVIKMKSSDFLESAEGKVSLAFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMAYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAIAEQQLIMAIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLE 6ocq B 2.79 BS01 M5J B 1 M67 L70 V76 L78 M92 L129 I154 A155 D156 F162 M59 L62 V68 L70 M84 L121 I146 A147 D148 F154 2.7.11.1 31013427 LNVIKMKSSDFLESAELDSGGKVSLAFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMAYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAIAEQQLIMAIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLE 6oii A 1.85 BS01 ACD A 1 L11 R15 W35 F37 Y46 I47 V50 F51 M54 L56 P63 L68 Q71 L72 V85 C88 V89 G104 F105 F108 I116 S119 I120 L10 R14 W34 F36 Y45 I46 V49 F50 M53 L55 P62 L67 Q70 L71 V84 C87 V88 G103 F104 F107 I115 S118 I119 EFTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEEVRTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASIK 6oii A 1.85 BS02 CO A 1 H70 H74 H69 H73 EFTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEEVRTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASIK 6oij R 3.30 BS01 IXO R 1 D105 Y106 S109 Q110 V113 A196 F197 W378 Y381 Y404 C407 Y408 D84 Y85 S88 Q89 V92 A175 F176 W225 Y228 Y251 C254 Y255 PWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASQASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIP 6oij R 3.30 BS02 Y01 R 1 Y198 V201 T202 C205 T206 I383 Y177 V180 T181 C184 T185 I230 PWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASQASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIP 6oij R 3.30 BS03 Y01 R 2 L65 C69 A143 I146 W150 L44 C48 A122 I125 W129 PWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASQASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIP 6oik R 3.60 BS01 IXO R 1 Y104 S107 N108 V111 W155 A194 F195 W400 Y403 N404 Y426 C429 Y430 Y85 S88 N89 V92 W136 A175 F176 W221 Y224 N225 Y247 C250 Y251 TFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMC 6oik R 3.60 BS02 2CU R 1 Y80 Y83 T84 Y177 F181 N419 W422 T423 Y61 Y64 T65 Y158 F162 N240 W243 T244 TFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMC 6oix A 3.15 BS01 GTP A 1 Q53 N121 H126 N186 Y212 K232 D268 Y272 D276 F391 V396 E400 Q51 N119 H124 N184 Y210 K230 D266 Y270 D274 F364 V369 E373 3.1.5.1 31019074 QIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHFSLVVENAWEKTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLESDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oix B 3.15 BS01 GTP B 1 Q53 V54 H117 H126 E184 K211 Y212 K231 K232 D268 Y272 D276 F391 E400 Q51 V52 H113 H122 E174 K201 Y202 K221 K222 D258 Y262 D266 F358 E367 3.1.5.1 31019074 QIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLEAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHFSLVVENAWEKSSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLESDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oix C 3.15 BS01 GTP C 1 Q53 V54 H126 N186 K211 Y212 K231 K232 Y272 D276 F391 V396 E400 Q51 V52 H123 N181 K206 Y207 K226 K227 Y267 D271 F365 V370 E374 3.1.5.1 31019074 QIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESPLTDDRCSVAALRLRGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWFSLVVENAWERSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLCSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oix E 3.15 BS01 GTP E 1 Q53 V54 H126 K211 Y212 K232 Y272 D276 F391 V396 E400 Q52 V53 H125 K201 Y202 K222 Y262 D266 F365 V370 E374 3.1.5.1 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAEDRCSVAALRLREPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHESLFSLVVENAWEKSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oix F 3.15 BS01 GTP F 1 Q53 V54 D118 H126 E184 N186 K211 Y212 K232 Y272 D276 F391 V396 E400 Q51 V52 D115 H123 E172 N174 K199 Y200 K220 Y260 D264 F365 V370 E374 3.1.5.1 31019074 QIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAERCSVAALRLGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGSLFSLVVENAWEKSRDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKEKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAV 6ok8 A 1.80 BS02 THP A 1 R35 D40 D83 Y85 R87 L89 Y113 Y115 R29 D34 D71 Y73 R75 L77 Y101 Y103 3.1.31.1 LHKEPATLIKAIDGDTVKLMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLRLAEAQAKKEKLNIWS 6okh A 1.85 BS01 MG A 1 H38 D79 I106 H35 D76 I103 IDLKTDKDFAELPEGTLAELLDGEIFMVPAPIPEHQRVIRKFSNALSTFVEKNKLGEVFFSPIDVYLDEHNVVQPDLIFISKARNTIIREKRIEGAPDWIAEILSEGNAYHDLKTKKRLYEKHGVAEYWIVDPMERSVEIYQNGNSGFTLLASADSGTVVSKMLDGFSLEIQTLFTKP 6omw F 2.10 BS01 PAM F 1 R15 W35 F37 Y46 I47 F51 M54 L56 L68 L72 V85 C88 G104 F105 F108 I116 I120 R13 W33 F35 Y44 I45 F49 M52 L54 L66 L70 V83 C86 G102 F103 F106 I114 I118 FTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEEVRTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASIK 6omw I 2.10 BS01 PAM I 1 R15 W35 F37 Y46 I47 V50 F51 M54 L56 L68 V85 C88 V89 G104 F105 F108 R13 W33 F35 Y44 I45 V48 F49 M52 L54 L66 V83 C86 V87 G102 F103 F106 FTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEEVRTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASIK 6omw E 2.10 BS01 PAM E 1 R15 F32 W35 F37 Y46 F51 M54 L56 L68 C88 G104 F108 I116 I120 R14 F31 W34 F36 Y45 F50 M53 L55 L67 C87 G103 F107 I115 I119 EFTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEEVRTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASI 6omz A 1.85 BS01 PMM A 1 R62 D94 N113 V115 M138 D185 F190 L215 G217 K221 R261 H263 R51 D83 N102 V104 M127 D174 F179 L204 G206 K210 R250 H252 2.5.1.15 TPVQVMGVVNVTQDSFSDGGKFIDTDRAVEHGLALVAAGAQIIDVGGESTRPGATRIDPGVEAARVTPVIRELAAQGITISIDTMHADVARAALEAGAHIVNDVSGGRADPGMAGVLAEAKVPWILMHWRSVDADHPHRVPGYRDVVAEVRTELLAAVDAAVTAGVEPERLVIDPGLGFAKTAEHNWALLHALPDLVATGVPVLVGASRKRFLGTLLAAADGTPRPPDGRETATAVISVLAAMHGAWGVRVHDVQASVDALKVLGAWTSGEQIG 6onq A 2.71 BS01 HEM A 1 E94 C95 C98 H99 Y108 A109 P110 L112 S115 R118 F124 I127 L128 K132 E134 Q141 V142 M143 P144 F146 E64 C65 C68 H69 Y78 A79 P80 L82 S85 R88 F94 I97 L98 K102 E104 Q106 V107 M108 P109 F111 31017712 PELANKLDPNAKEIDEPVLKAATAAKEEDGKYFDKDGHPTFHITNDGKKVDWFTYSGYRRYHAECHVCHGPDGMGSTYAPALKDSLKRLSYEEFYGILAGGKQENQVMPAFGDNKNVMCYANDLYVYLRARAAGAWGRARPGEKEDKPESAKTVEKECL 6opb E 2.00 BS01 DCR E 1 L11 R15 F32 K33 W35 F37 Y46 I47 F51 M54 L56 L68 Q71 L72 G104 F105 F108 I116 S119 I120 L10 R14 F31 K32 W34 F36 Y45 I46 F50 M53 L55 L67 Q70 L71 G103 F104 F107 I115 S118 I119 EFTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEEVRTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASIK 6opb F 2.00 BS01 DCR F 1 L11 R15 F32 K33 W35 F37 Y46 I47 F51 L56 L68 L72 G104 F105 F108 I116 L10 R14 F31 K32 W34 F36 Y45 I46 F50 L55 L67 L71 G103 F104 F107 I115 EFTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEEVRTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASIK 6opb I 2.00 BS01 DCR I 1 R15 F32 K33 W35 F37 Y46 I47 F51 M54 L56 P63 L68 Q71 L72 V85 C88 V89 G104 F108 I116 I120 R14 F31 K32 W34 F36 Y45 I46 F50 M53 L55 P62 L67 Q70 L71 V84 C87 V88 G103 F107 I115 I119 EFTVSTTEDLQRYRTECVSSLNIPADYVEKFKKWEFPEDDTTMCYIKCVFNKMQLFDDTEGPLVDNLVHQLAHGRDAEEVRTEVLKCVDKNTDNNACHWAFRGFKCFQKNNLSLIKASIK 6q63 A 2.44 BS01 CU A 1 C282 C301 C342 C345 C259 C278 C319 C322 3.2.1.52 QEEANYQIIPLPQEIVTSQVNPFILKSGVKILYPEGNEKMQRNAQFLADYLKTATGKDFSIEAGTEGKNAIVLALGSEVENPESYQLKVTDQGVTITAPTEAGVFYGIQTLRKSLPIALGADVALPAVEIKDAPRFGYRGAHFDVSRHFFTIDEVKTYIDMLALHNMNRLHWHITDDQGWRLEIKKYPKLTEIGSQRSGTVIGRNSGEYDNTPYGGFYTQEQAKEIVDYAAERYITVVPEIDLPGHMLAALAAYPELGCTGGPYEVWRQWGVADDVLCAGNDQVLKFLEDVYGELIEIFPSEYIHVGGDECPKVRWEKCPKCQARIKALGLKSDKNHSKEERLQSFVINHIEKFLNDHGRQIIGWDEILEGGLAPNATVMSWRGESGGIEAAKQKHDVIMTPNTYLYFDYYQAKDTENEPFGIGGYLPMERVYSYEPMPASLTPDEQQYIKGVQANLWTEYIATFSHAQYMVLPRWAALCEVQWSTPDKKNYEDFLSRLPRLIKWYDAEGYNYAKHVFDVKAEFTPNPADGTLDITLTTIDNAPIHYTLDGTEPTSTSPVYDGALKIKENADFSAIAIRPTGNSRVVSEKIDFSKSSMKPIVANQPVNKQYEFKGVSTLVDGLKGNGNYKTGRWIAFRGNDMDVTIDLKQPTEISSVAISTCVEKGDWVFDTRGLSVEVSEDGTNFTKVASEAYPAMKETDKNGVYDHKLTFTPVTAQYVKVIASPEKSIPEWHGGKSYPGFLFVDEITIN 6q63 A 2.44 BS02 CA A 1 T641 D644 L646 D769 E770 T618 D621 L623 D746 E747 3.2.1.52 QEEANYQIIPLPQEIVTSQVNPFILKSGVKILYPEGNEKMQRNAQFLADYLKTATGKDFSIEAGTEGKNAIVLALGSEVENPESYQLKVTDQGVTITAPTEAGVFYGIQTLRKSLPIALGADVALPAVEIKDAPRFGYRGAHFDVSRHFFTIDEVKTYIDMLALHNMNRLHWHITDDQGWRLEIKKYPKLTEIGSQRSGTVIGRNSGEYDNTPYGGFYTQEQAKEIVDYAAERYITVVPEIDLPGHMLAALAAYPELGCTGGPYEVWRQWGVADDVLCAGNDQVLKFLEDVYGELIEIFPSEYIHVGGDECPKVRWEKCPKCQARIKALGLKSDKNHSKEERLQSFVINHIEKFLNDHGRQIIGWDEILEGGLAPNATVMSWRGESGGIEAAKQKHDVIMTPNTYLYFDYYQAKDTENEPFGIGGYLPMERVYSYEPMPASLTPDEQQYIKGVQANLWTEYIATFSHAQYMVLPRWAALCEVQWSTPDKKNYEDFLSRLPRLIKWYDAEGYNYAKHVFDVKAEFTPNPADGTLDITLTTIDNAPIHYTLDGTEPTSTSPVYDGALKIKENADFSAIAIRPTGNSRVVSEKIDFSKSSMKPIVANQPVNKQYEFKGVSTLVDGLKGNGNYKTGRWIAFRGNDMDVTIDLKQPTEISSVAISTCVEKGDWVFDTRGLSVEVSEDGTNFTKVASEAYPAMKETDKNGVYDHKLTFTPVTAQYVKVIASPEKSIPEWHGGKSYPGFLFVDEITIN 6qfe A 1.67 BS01 J08 A 1 H57 H96 D189 S190 C191 Q192 S195 V213 S214 W215 G216 D217 Y218 C220 G226 H42 H81 D173 S174 C175 Q176 S179 V193 S194 W195 G196 D197 Y198 C200 G207 3.4.21.- IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 6qff A 1.64 BS01 J08 A 1 H57 H99 D189 S190 C191 Q192 S195 V213 S214 W215 G216 N217 I218 C220 H41 H82 D170 S171 C172 Q173 S176 V190 S191 W192 G193 N194 I195 C197 3.4.21.- LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 6qff B 1.64 BS01 J08 B 1 H57 Y94 H99 D189 S190 C191 Q192 S195 V213 S214 W215 G216 N217 I218 C220 H41 Y77 H82 D170 S171 C172 Q173 S176 V190 S191 W192 G193 N194 I195 C197 3.4.21.- LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 6qfg A 1.68 BS01 J08 A 1 H57 A96 H99 D189 S190 C191 S195 V213 S214 W215 G216 N217 Y218 C220 G226 H41 A79 H82 D170 S171 C172 S176 V190 S191 W192 G193 N194 Y195 C197 G204 3.4.21.- LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNYPCGSKEKPGVYTNVCRYTNWIQKTIQAK 6qfg B 1.68 BS01 J08 B 1 H57 H99 D189 S190 C191 S195 V213 S214 W215 G216 N217 Y218 C220 H41 H82 D170 S171 C172 S176 V190 S191 W192 G193 N194 Y195 C197 3.4.21.- LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNYPCGSKEKPGVYTNVCRYTNWIQKTIQA 6qfh A 1.65 BS01 J08 A 1 H57 H99 D189 S190 C191 Q192 S195 V213 S214 W215 G216 D217 Y218 C220 H41 H82 D170 S171 C172 Q173 S176 V190 S191 W192 G193 D194 Y195 C197 3.4.21.- LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGDYPCGSKERPGVYTNVCRYTNWIQKTIQA 6qxf A 3.60 BS01 CA A 1 D122 E123 E128 D122 E123 E128 MKINFSLLDEPMEVNLGTVLVIEDVSVFAQLVKEFYQYDEQSNLTIFDSKIRSIRSSELLLITDILGYDINTSQVLKLLHTDIVSQLNDKPEVRSEIDSLVSLITDIIMAECIENELDIEYDEITLLELIKALGVRIETKSCTVFEKIFEILQIFKYLVKKRILVFVNSLSYFSKDEIYQILEYTKLSQADVLFLEPRQIEGIQQFILDKDYILMPYN 6qxf A 3.60 BS02 CA D 1 A132 L133 A132 L133 MKINFSLLDEPMEVNLGTVLVIEDVSVFAQLVKEFYQYDEQSNLTIFDSKIRSIRSSELLLITDILGYDINTSQVLKLLHTDIVSQLNDKPEVRSEIDSLVSLITDIIMAECIENELDIEYDEITLLELIKALGVRIETKSCTVFEKIFEILQIFKYLVKKRILVFVNSLSYFSKDEIYQILEYTKLSQADVLFLEPRQIEGIQQFILDKDYILMPYN 6qxf F 3.60 BS01 NUC Y 1 S73 K77 S73 K77 MKINFSLLDEPMEVNLGTVLVIEDVSVFAQLVKEFYQYDEQSNLTIFDSKIRSIRSSELLLITDILGYDINTSQVLKLLHTDIVSQLNDKPEVRSEIDSLVSLITDIIMAECIENELDIEYDEITLLELIKALGVRIETKSCTVFEKIFEILQIFKYLVKKRILVFVNSLSYFSKDEIYQILEYTKLSQADVLFLEPRQIEGIQQFILDKDYILMPYNN 6qxf J 3.60 BS01 III K 1 W4 R5 T6 V7 V8 V9 N10 I11 F24 E31 E44 R72 V239 K243 F246 Y261 W2 R3 T4 V5 V6 V7 N8 I9 F22 E29 E42 R70 V237 K241 F244 Y259 3.1.-.- GWRTVVVNIHSKLSYKNNHLIFRNSYKTEMIHLSEIDILLLETTDIVLTTMLVKRLVDENILVIFCDDKRLPTAFLTPYYARHDSSLQIARQIAWKENVKCEVWTAIIAQKILNQSYYLGECSFFEKSQSIMELYHGLERFDPSNREGHSARIYFNTLFGNDFTRESDNDINAALDYGYTLLLSMFAREVVVCGCMTQIGLKHANQFNQFNLASDIMEPFRPIIDRIVYQNRHNNFVKIKKELFSIFSETYLYNGKEMYLSNIVSDYTKKVIKALNQLGEEIPEFRI 6r3q B 3.40 BS01 GSP B 1 A48 G49 E50 G52 K53 S54 T55 R199 R201 L203 T204 N292 K293 L296 C365 A366 V367 A21 G22 E23 G25 K26 S27 T28 R150 R152 L154 T155 N243 K244 L247 C316 A317 V318 31023924 KQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ 6r3q B 3.40 BS02 MG B 1 K53 S54 T204 D223 K26 S27 T155 D174 31023924 KQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ 6r3v B 1.75 BS03 PO4 B 1 A15 K18 T37 A61 G62 Q63 A14 K17 T27 A51 G52 Q53 31038818 AAIRKKLVIVGDGACGKTCLLIVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQAR 6r41 A 2.21 BS01 SIA A 1 P197 S198 P199 N200 S456 F457 S458 Y469 P173 S174 P175 N176 S424 F425 S426 Y437 30367053 ANTFLVKEDSKNVTAYTPFATPITDSKSDLVSLAQLDSSYQIADQTIHNTNLFVLFKSRDVKVKYESSGSNNISFDSTSQGEKPSYVVEFTNSTNIGIKWTMVKKYQLDVPNVSSDMNQVLKNLILEQPLTKYTLNSSLAKEKGKTQREVHLGSGQANQWTSQRNQHDLNNNPSPNASTGFKLTTGNAYRKLSESWPIYEPIDGTKQGKGKDSSGWSSTEENEAKNDAPSVSSSGTFNKYLNTKQALESIGILFDDQTPRNVITQLYYASTSKLAVTNNHIVVMGNSFLPSMWYWVVERSAQENASNKPTWFANTNLDWGEDKQKQFVENQLGYKETTSTNSHNFHSKSFTQPAYLISGIDSVNDQIIFSGFKAGSVGYDSSSSSSSTKDQALAWSTTTSLDSKTGYKDLVTNDTGLNGPINGSFSIQDTFSFVVPYSTTGPIKTAYPVKKDQKSTVKINSLINATPLNSYGDEGIGVFDALGLNYNFKSNQERLPSRTDQIFVYGIVSPNELRSAKSSADSTGSDTKVNWSNTQSRYLPVPYNYSEGIIDASVTTFSGLKSIAPDGFANSIANFSVGLKAGIDPNPVMSGKKANYGAVVLTRGGVVRLNFNPGNDSLLSTTDNNIAPISFSFTPFTAAESAVDLTTFKEVTYNQESGLWSYIFDSSLKPSHDGKQTPVTDNMGFSVITVSRTGIELNQDQATTTLDVAPSALAVQSGIQSTTQTLTGVLPLSEEFSAVIAKDSDQNKIDIYKNNNGLFEIDTQLSNSVATNNGGLAPSYTENRVDAWGKVEFADNSVLQARNLVDKTVDEIINTPEILNSFFRFTPAFEDQKATLVATKQSDTSLSVSPRIQFLDGNFYDLNSTIAGVPLNIGFPSRVFAGFAAL 6r49 A 2.21 BS01 ADP A 1 L139 G140 K141 G142 K143 G145 V147 A160 K162 L194 E211 A213 T217 E260 N261 L263 D274 L13 G14 K15 G16 K17 G19 V21 A34 K36 L68 E85 A87 T91 E134 N135 L137 D148 2.7.11.1 31026091 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 6r49 A 2.21 BS03 JSB A 1 K166 E175 L178 R179 Y199 H201 V206 K40 E49 L52 R53 Y73 H75 V80 2.7.11.1 31026091 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 6r4a A 1.94 BS01 ADP A 1 G140 G142 K143 F144 G145 V147 A160 K162 L194 E211 A213 T217 E260 N261 L263 D274 G14 G16 K17 F18 G19 V21 A34 K36 L68 E85 A87 T91 E134 N135 L137 D148 2.7.11.1 31026091 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 6r4a A 1.94 BS03 JRT A 1 L178 R179 E183 Y199 H201 L52 R53 E57 Y73 H75 2.7.11.1 31026091 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 6r4b A 2.15 BS03 JSN A 1 K166 E175 L178 R179 Y199 V206 K40 E49 L52 R53 Y73 V80 2.7.11.1 31026091 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 6r4o A 4.20 BS01 ONM A 1 D399 I400 V401 G402 F403 T404 S407 L415 L441 G442 D443 M1116 W1188 G1189 D1190 N1193 D249 I250 V251 G252 F253 T254 S257 L265 L291 G292 D293 M712 W784 G785 D786 N789 31023924 SVNLEEACMERCFPQTQRRFRYALFYIGFACLLWSIYFGVHMKSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLTLLVFALTLAAQFQVLTPCLSQVGSFSMCIEVLFLLYTVMHLPLYLSLILGVAYSVLFETFGYHHWELLSRALLHLCIHAIGIHLFIMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVTELKTYLIAGQFASATFSSLLDVLLSTTVFLILSITCFLRYGAASTPPPPAALAVFGAALLLEILSLVVSVRMVFFLEDVMTCTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTMFTGSAVLTAVVQYCNFCQLSSWMRSSLATVVGAGPLLLLLYVSASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGSHPQEHLQILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYEFDYRGTVNVKGKGQMKTYLYPK 6r4o A 4.20 BS02 FOK A 1 S511 V514 N515 N518 I1111 G1112 A1113 S361 V364 N365 N368 I707 G708 A709 31023924 SVNLEEACMERCFPQTQRRFRYALFYIGFACLLWSIYFGVHMKSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLTLLVFALTLAAQFQVLTPCLSQVGSFSMCIEVLFLLYTVMHLPLYLSLILGVAYSVLFETFGYHHWELLSRALLHLCIHAIGIHLFIMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVTELKTYLIAGQFASATFSSLLDVLLSTTVFLILSITCFLRYGAASTPPPPAALAVFGAALLLEILSLVVSVRMVFFLEDVMTCTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTMFTGSAVLTAVVQYCNFCQLSSWMRSSLATVVGAGPLLLLLYVSASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGSHPQEHLQILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYEFDYRGTVNVKGKGQMKTYLYPK 6r4o A 4.20 BS03 MN A 1 D399 D443 C444 D249 D293 C294 31023924 SVNLEEACMERCFPQTQRRFRYALFYIGFACLLWSIYFGVHMKSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLTLLVFALTLAAQFQVLTPCLSQVGSFSMCIEVLFLLYTVMHLPLYLSLILGVAYSVLFETFGYHHWELLSRALLHLCIHAIGIHLFIMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVTELKTYLIAGQFASATFSSLLDVLLSTTVFLILSITCFLRYGAASTPPPPAALAVFGAALLLEILSLVVSVRMVFFLEDVMTCTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTMFTGSAVLTAVVQYCNFCQLSSWMRSSLATVVGAGPLLLLLYVSASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGSHPQEHLQILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYEFDYRGTVNVKGKGQMKTYLYPK 6r4o A 4.20 BS04 MN A 2 D399 I400 V401 G402 D443 D249 I250 V251 G252 D293 31023924 SVNLEEACMERCFPQTQRRFRYALFYIGFACLLWSIYFGVHMKSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLTLLVFALTLAAQFQVLTPCLSQVGSFSMCIEVLFLLYTVMHLPLYLSLILGVAYSVLFETFGYHHWELLSRALLHLCIHAIGIHLFIMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVTELKTYLIAGQFASATFSSLLDVLLSTTVFLILSITCFLRYGAASTPPPPAALAVFGAALLLEILSLVVSVRMVFFLEDVMTCTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTMFTGSAVLTAVVQYCNFCQLSSWMRSSLATVVGAGPLLLLLYVSASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGSHPQEHLQILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYEFDYRGTVNVKGKGQMKTYLYPK 6r4o B 4.20 BS01 GSP B 1 A48 G49 E50 S51 G52 K53 S54 T55 L198 R199 C200 R201 V202 T204 V224 G225 N292 K293 L296 C365 A366 A21 G22 E23 S24 G25 K26 S27 T28 L149 R150 C151 R152 V153 T155 V175 G176 N243 K244 L247 C316 A317 31023924 KQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ 6r4p B 3.10 BS01 GSP B 1 G49 E50 S51 G52 K53 S54 T55 C174 L198 R199 R201 L203 T204 G226 N292 K293 L296 C365 A366 V367 G22 E23 S24 G25 K26 S27 T28 C125 L149 R150 R152 L154 T155 G177 N243 K244 L247 C316 A317 V318 31023924 KQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ 6r8p A 1.45 BS01 JVB A 1 W128 Y129 T236 F268 F319 F320 V346 W41 Y42 T149 F181 F232 F233 V259 3.1.1.98 DLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRSPVFVVQWLFDEAQLTVDNVHPVQEGLRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHTPLKGCPVHLVDSCPWPHCNPSCPT 6r8q A 1.50 BS01 JV5 A 1 W128 Y129 S232 A233 T236 F268 P287 I291 F319 F320 A342 V346 W42 Y43 S146 A147 T150 F182 P201 I205 F233 F234 A256 V260 3.1.1.98 EDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRSPVFVVQWLFDEAQLTVDNVHLTGQPVQEGLRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHDTPLKGCPVHLVDSCPWPHCNPSCPTG 6r8r A 1.27 BS01 JV8 A 1 W128 Y129 V187 F268 P287 I291 F320 T345 V346 W43 Y44 V102 F183 P202 I206 F235 T260 V261 3.1.1.98 NEDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRSPVFVVQWLFDEAQLTVDNVHLTGQPVQEGLRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHDTPLKGCPVHLVDSCPWPHCNPSCPTGT 6ra4 A 1.90 BS01 NUC L 1 K258 H263 M267 R269 R272 F286 L288 Y303 F304 R307 H308 K327 H328 T329 Y330 K46 H51 M55 R57 R60 F74 L76 Y85 F86 R89 H90 K109 H110 T111 Y112 3.1.26.- 31021613 PTAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 6ra4 A 1.90 BS02 NUC M 1 Q266 M267 K268 Q54 M55 K56 3.1.26.- 31021613 PTAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 6ra4 B 1.90 BS01 NUC L 1 Q266 M267 K268 Q55 M56 K57 3.1.26.- 31021613 GPTAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIK 6ra4 B 1.90 BS02 NUC M 1 F216 K258 H263 M267 R269 Y271 R272 F286 L288 Y303 F304 R307 H308 K327 H328 T329 Y330 L331 G341 F5 K47 H52 M56 R58 Y60 R61 F75 L77 Y87 F88 R91 H92 K111 H112 T113 Y114 L115 G125 3.1.26.- 31021613 GPTAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIK 6rk0 A 0.99 BS01 HEM A 1 F59 H70 G71 S72 F134 L138 W143 A156 T157 F50 H61 G62 S63 F125 L129 W134 A147 T148 PEAPSDRTHVKRYHWLARYDQETVKAILDATPLAHVGCMMNGVPFVTPTFFWREGDRVYWHGSSAGRLFKALEHQDICLTVSLLDGLVIARSAYNFNCNFRSVMLLGRAELISDEAVKAEKLRNFVDGLIPGEWERLRPVHAKEIEATAVASLSIAEASCKVRTGPPLDDEEDYAFPSWAGVIPIRYQVLPPEPDPRNLPDVPMPEDILKFRLG 6rk0 A 0.99 BS02 FAD B 1 L42 F54 T56 P57 T58 F59 H70 G71 R76 L33 F45 T47 P48 T49 F50 H61 G62 R67 PEAPSDRTHVKRYHWLARYDQETVKAILDATPLAHVGCMMNGVPFVTPTFFWREGDRVYWHGSSAGRLFKALEHQDICLTVSLLDGLVIARSAYNFNCNFRSVMLLGRAELISDEAVKAEKLRNFVDGLIPGEWERLRPVHAKEIEATAVASLSIAEASCKVRTGPPLDDEEDYAFPSWAGVIPIRYQVLPPEPDPRNLPDVPMPEDILKFRLG 6rk0 A 0.99 BS03 FAD B 2 R16 T17 H18 V19 K20 R21 C107 F109 S111 M113 S168 K170 R7 T8 H9 V10 K11 R12 C98 F100 S102 M104 S159 K161 PEAPSDRTHVKRYHWLARYDQETVKAILDATPLAHVGCMMNGVPFVTPTFFWREGDRVYWHGSSAGRLFKALEHQDICLTVSLLDGLVIARSAYNFNCNFRSVMLLGRAELISDEAVKAEKLRNFVDGLIPGEWERLRPVHAKEIEATAVASLSIAEASCKVRTGPPLDDEEDYAFPSWAGVIPIRYQVLPPEPDPRNLPDVPMPEDILKFRLG 6rk0 A 0.99 BS04 HEM B 1 R21 Y22 L25 L96 A102 Y103 F105 N106 K170 R12 Y13 L16 L87 A93 Y94 F96 N97 K161 PEAPSDRTHVKRYHWLARYDQETVKAILDATPLAHVGCMMNGVPFVTPTFFWREGDRVYWHGSSAGRLFKALEHQDICLTVSLLDGLVIARSAYNFNCNFRSVMLLGRAELISDEAVKAEKLRNFVDGLIPGEWERLRPVHAKEIEATAVASLSIAEASCKVRTGPPLDDEEDYAFPSWAGVIPIRYQVLPPEPDPRNLPDVPMPEDILKFRLG 6rk0 B 0.99 BS01 HEM A 1 R21 Y22 L25 A102 Y103 F105 N106 K170 R12 Y13 L16 A93 Y94 F96 N97 K161 PEAPSDRTHVKRYHWLARYDQETVKAILDATPLAHVGCMMNGVPFVTPTFFWREGDRVYWHGSSAGRLFKALEHQDICLTVSLLDGLVIARSAYNFNCNFRSVMLLGRAELISDEAVKAEKLRNFVDGLIPGEWERLRPVHAKEIEATAVASLSIAEASCKVRTGPPLDDEEDYAFPSWAGVIPIRYQVLPPEPDPRNLPDVPMPEDILKFRLG 6rk0 B 0.99 BS04 HEM B 1 F59 H70 S72 L131 F134 V135 L138 W143 A156 T157 F50 H61 S63 L122 F125 V126 L129 W134 A147 T148 PEAPSDRTHVKRYHWLARYDQETVKAILDATPLAHVGCMMNGVPFVTPTFFWREGDRVYWHGSSAGRLFKALEHQDICLTVSLLDGLVIARSAYNFNCNFRSVMLLGRAELISDEAVKAEKLRNFVDGLIPGEWERLRPVHAKEIEATAVASLSIAEASCKVRTGPPLDDEEDYAFPSWAGVIPIRYQVLPPEPDPRNLPDVPMPEDILKFRLG 6rk9 A 2.29 BS01 III C 1 E390 R393 S394 N395 Q431 F432 L433 G434 M436 L465 L466 H493 F496 R526 F529 H530 L564 Y565 E617 L619 Q664 K666 H679 T680 P682 R686 R688 A757 I758 E61 R64 S65 N66 Q102 F103 L104 G105 M107 L136 L137 H164 F167 R197 F200 H201 L235 Y236 E288 L290 Q335 K337 H350 T351 P353 R357 R359 A428 I429 1.14.11.16 KPKLLNKFDKTIKAELDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGNKEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPKETGYTELVKSLERNWKLIRDEGLAVMDKAKGLFLPEDENLREKGDWSQFTLWQQGRRNENACKGAPKTCTLLEKFPETTGCRRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETKTWEEGKVLIFDDSFEHEVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI 6rk9 A 2.29 BS03 OGA A 1 W625 S668 M670 R688 H690 H725 V727 R735 I737 I739 W296 S339 M341 R359 H361 H396 V398 R406 I408 I410 1.14.11.16 KPKLLNKFDKTIKAELDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLGDAMQRVGNKEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPKETGYTELVKSLERNWKLIRDEGLAVMDKAKGLFLPEDENLREKGDWSQFTLWQQGRRNENACKGAPKTCTLLEKFPETTGCRRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIRCANETKTWEEGKVLIFDDSFEHEVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI