5z3f A 1.10 BS01 BGC A 1 A41 Y48 W53 R55 D56 W176 W177 E178 R284 F290 L361 W363 A33 Y40 W45 R47 D48 W168 W169 E170 R276 F282 L353 W355 D2PPM8 GLDSHELARLHELARHSHAVITRHQDAGGAYPAAPTFSAYRGYAWLRDGSFTAEGISRYGDVASAGRFHDWVDGVLRRRRGQVDDLLAAVDRGEVPSNEGMLPTRFTFDGNDGSDPWWDFQTDGYGMWLWSVVTHAARHGLDLERWRAGIDVAVDYLLAFWDRPCYDWWEEHVEHRHVSTLGAIHGGLVAVGTCAALRSAPWSAATLQVAARIRSLVSAEGVVDGHLVKWLGSSAVDGSLPACVVPFGLVPPDDDVAAMTRAAVAKDLDVDGGVHRFAADVFYGGGQWILLSALLGWNLAAAGDTAGALRHLRWIADQADADGDLPAQVPHHLLHPGSRAEWVARWGTVATPLLWSHGMYLILADELGLLP 5zuu C 1.95 BS01 NUC F 1 K243 S244 N245 N249 W259 A260 Q262 N286 R287 R289 W310 Y319 F335 K352 I353 S354 R355 D356 K23 S24 N25 N29 W39 A40 Q42 N66 R67 R69 W90 Y99 F115 K132 I133 S134 R135 D136 3.1.21.- A9LNK9 PADQTNRTSHPLPQGVNRYFVVKSNNRENFELSVQQGVWATQRSNEAKLNEAFDSVENVILIFSVNRTRHFQGCAKMTSRIGGYIGGGNWKHEHGTAQYGRNFSVKWLKLCELSFHKTRNLRNPYNENLPVKISRDCQELEPSVGEQLASLLYLEPDSELMAISIAAEAKREEE 5zuu D 1.95 BS01 NUC G 1 K243 S244 N245 N249 W259 A260 Q262 N286 R287 R289 F331 K348 I349 S350 R351 D352 K15 S16 N17 N21 W31 A32 Q34 N58 R59 R61 F89 K106 I107 S108 R109 D110 3.1.21.- A9LNK9 SHPLPQGVNRYFVVKSNNRENFELSVQQGVWATQRSNEAKLNEAFDSVENVILIFSVNRTRHFQGCAKMTSRIGRNFSVKWLKLCELSFHKTRNLRNPYNENLPVKISRDCQELEPSVGEQLASLLYLEPDSELMAISIAAEAKREE 5zvp A 1.42 BS01 GDP A 1 A15 C16 G17 K18 T19 C20 F30 V35 K118 D120 L121 S160 A161 R162 A15 C16 G17 K18 T19 C20 F30 V35 K118 D120 L121 S160 A161 R162 A0A068C8U8 MAEIRRKLVIVGDGACGKTCLLIVNSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQEDYDRLRPLSYPDSHVILICFAIDSPDSLDNVQEKWISEVLHFCQGLPIILVGCKKDLRHDPKTIEELHKTSQKPVTPEQGEEVRKKIGAYKYLECSARTNEGVREVFEAATRAALLT 5zvp A 1.42 BS02 MG A 1 T19 T37 T19 T37 A0A068C8U8 MAEIRRKLVIVGDGACGKTCLLIVNSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQEDYDRLRPLSYPDSHVILICFAIDSPDSLDNVQEKWISEVLHFCQGLPIILVGCKKDLRHDPKTIEELHKTSQKPVTPEQGEEVRKKIGAYKYLECSARTNEGVREVFEAATRAALLT 5zwk A 2.10 BS01 FBP A 1 D118 D121 G122 S123 S124 N212 Y215 Y244 G246 S247 M248 Y264 K274 E280 D102 D105 G106 S107 S108 N196 Y199 Y228 G230 S231 M232 Y248 K258 E264 Q2TU34 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk A 2.10 BS03 MG A 1 D118 D121 E280 D102 D105 E264 Q2TU34 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk A 2.10 BS04 MG A 2 D118 L120 D121 D102 L104 D105 Q2TU34 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk B 2.10 BS01 FBP B 1 E97 D121 G122 S123 N212 Y215 Y244 G246 M248 Y264 K274 L275 E280 E81 D105 G106 S107 N196 Y199 Y228 G230 M232 Y248 K258 L259 E264 Q2TU34 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk B 2.10 BS03 MG B 1 E97 D118 L120 D121 E81 D102 L104 D105 Q2TU34 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk C 2.10 BS01 FBP C 1 E97 D118 D121 G122 S123 N212 Y215 Y244 G246 S247 M248 Y264 K274 E280 E81 D102 D105 G106 S107 N196 Y199 Y228 G230 S231 M232 Y248 K258 E264 Q2TU34 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk D 2.10 BS01 FBP D 1 E97 D118 L120 D121 G122 S123 N212 Y215 Y244 G246 M248 Y264 K274 R276 E280 E81 D102 L104 D105 G106 S107 N196 Y199 Y228 G230 M232 Y248 K258 R260 E264 Q2TU34 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk D 2.10 BS03 MG D 1 E97 D118 L120 E81 D102 L104 Q2TU34 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 5zwk D 2.10 BS04 MG D 2 E97 D118 D121 R276 E280 E81 D102 D105 R260 E264 Q2TU34 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 6a6r A 2.61 BS01 FAD A 1 V12 G13 G16 T17 L39 D40 S46 Q48 S49 A50 K56 I57 G185 T186 F187 A220 G221 W223 L227 C347 C349 D374 G376 H377 S378 F379 K380 V10 G11 G14 T15 L36 D37 S43 Q45 S46 A47 K53 I54 G178 T179 F180 A213 G214 W216 L220 C338 C340 D365 G367 H368 S369 F370 K371 30700768 PRANTKIIVVGGGGTGSSTALHLLRAGYTPSNITVLDTYPIPSAQSAGYDLNKIFGIRLRNKPDLQLYLEALDWKNDPLFKPFFHNVGQDVSSTEEGIKKLRRYQSLLDAGIGLEKTNFLLESEDEILAKAPHFTREQIKGWKGLFGDGGWLAAAKAINAIGQFLKEQGVKFGFGEAGTFKKPLFADADEKTCIGVETVDGTKYYADKVVLAAGAWSSTLVDLEEQCVSKAWVFAHIQLTPAEAAAYKNTPVIYDGDYGFFIEPDENGIIKVCDEFPGFTHFKHQPYGSPVPKLISVPRSHAKHPTDTYPHASEVTIKKAINRFLPRFNDKELFNRACWCTDTADANLLVCEHPRWKGFYLATGDSGHSFKLLPNIGKHVVELLEGRLESVFKDAWRWRPGSGDALKSRRAAPAKDLADPGWR 6a6s A 1.85 BS02 FSA A 1 W239 F267 E282 G376 H377 K380 R419 W232 F260 E275 G367 H368 K371 R410 30700768 PRANTKIIVVGGGGTGSSTALHLLRAGYTPSNITVLDTYPIPSAQSAGYDLNKIFGIRLRNKPDLQLYLEALDWKNDPLFKPFFHNVGQDVSSTEEGIKKLRRYQSLLDAGIGLEKTNFLLESEDEILAKAPHFTREQIKGWKGLFGDGGWLAAAKAINAIGQFLKEQGVKFGFGEAGTFKKPLFADADEKTCIGVETVDGTKYYADKVVLAAGAWSSTLVDLEEQCVSKAWVFAHIQLTPAEAAAYKNTPVIYDGDYGFFIEPDENGIIKVCDEFPGFTHFKHQPYGSPVPKLISVPRSHAKHPTDTYPHASEVTIKKAINRFLPRFNDKELFNRACWCTDTADANLLVCEHPRWKGFYLATGDSGHSFKLLPNIGKHVVELLEGRLESVFKDAWRWRPGSGDALKSRRAAPAKDLADPGWR 6a6u A 1.95 BS01 FAD A 1 V12 G13 G15 G16 T17 M18 L39 D40 S46 Q48 S49 A50 K56 I57 G185 T186 F187 A219 A220 G221 W223 L227 W239 C347 C349 D374 G376 H377 S378 F379 K380 V10 G11 G13 G14 T15 M16 L37 D38 S44 Q46 S47 A48 K54 I55 G182 T183 F184 A216 A217 G218 W220 L224 W236 C344 C346 D371 G373 H374 S375 F376 K377 30700768 PRANTKIIVVGGGGTMGSSTALHLLRAGYTPSNITVLDTYPIPSAQSAGYDLNKIFGIGLRNKPDLQLYLEALDMWKNDPLFKPFFHNVGQMDVSSTEEGIKKLRMRYQSLLDAGIGLEKTNFLLESEDEILAKAPHFTREQIKGWKGLFGDGGWLAAAKAINAIGQFLKEQGVKFGFGEAGTFKKPLFADADEKTCIGVETVDGTKYYADKVVLAAGAWSSTLVDLEEQCVSKAWVFAHIQLTPAEAAAYKNTPVIYDGDYGFFIEPDENGIIKVCDEFPGFTHFKMHQPYGSPVPKLISVPRSHAKHPTDTYPHASEVTIKKAINRFLPRFNDKELFNRAMCWCTDTADANLLVCEHPRWKGFYLATGDSGHSFKLLPNIGKHVVELLEGRLESVFKDAWRWRPGSGDALKSRRAAPAKDLADMPGWRN 6a6v A 2.90 BS01 FAD A 1 V12 G13 G16 T17 M18 D40 S46 Q48 S49 A50 K56 I57 G185 T186 F187 A220 G221 W223 L227 W239 F241 C347 C349 D374 H377 S378 F379 K380 V10 G11 G14 T15 M16 D38 S44 Q46 S47 A48 K54 I55 G183 T184 F185 A218 G219 W221 L225 W237 F239 C345 C347 D372 H375 S376 F377 K378 30700768 PRANTKIIVVGGGGTMGSSTALHLLRAGYTPSNITVLDTYPIPSAQSAGYDLNKIFGISGANKPDLQLSLEAFDMWKNDPLFKPFFHNVGQMDVSSTEEGIKKLRKRYQSLLRAGIGLEKTNFLLESEDEILAKAPHFTREQIKGWKGLFCGDGGWLAAAKAINAIGQFLKEQGVKFGFGEAGTFKKPLFADADEKTCIGVETVDGTKYYADKVVLAAGAWSSTLVDLEEQCVSKAWVFAHIQLTPAEAAAYKNTPVIYDGDYGFFIEPDENGIIKVCDEFPGFTHFKMHQPYGSPVPKLISVPRSHAKHPTDTYPHASEVTIKKAINRFLPRFNDKELFNRAMCWCTDTADANLLVCEHPRWKGFYLATGDSGHSFKLLPNIGKHVVELLEGRLESVFKDAWRWRPGSGDALKSRRAAPAKDLADMPGWRN 6bs3 A 2.30 BS01 ADP A 1 G31 T32 G33 K34 S35 T36 N240 R241 P316 T317 V318 V322 G21 T22 G23 K24 S25 T26 N230 R231 P306 T307 V308 V312 P9WKX5 SVGWPSRLSGVRLHLVTGKGGTGKSTIAAALALTLAAGGRKVLLVEVEGRQGIAQLFDVPPLPYQELKIATAERGGQVNALAIDIEAAFLEYLDMFYNLGIAGRAMRRIGAVEFATTIAPGLRDVLLTGKIKETVVRLDKNKLPVYDAIVVDAPPTGRIARFLDVTKAVSDLAKGGPVHAQSEGVVKLLHSNQTAIHLVTLLEALPVQETLEAIEELAQMELPIGSVIVNRNIPAHLEPQDLAKAAEGEVDADSVRAGLLTAGVKLPDADFAGLLTETIQHATRITARAEIAQQLDALQVPRLELPTVSDGVDLGSLYELSESLAQQGVR 6bs3 B 2.30 BS01 ADP B 1 G29 V30 G31 K32 T33 T34 N283 R284 V353 P354 S355 L356 D359 V360 L369 G25 V26 G27 K28 T29 T30 N269 R270 V333 P334 S335 L336 D339 V340 L349 PKTLDMGAILADTSNRVVVCCGAGGVGKTTTAAALALRAAEYGRTVVVLTIDPAKRLAQALGINDLGNTPQRVPLAPEVPGELHAMMLDMRRTFDEMVMQYSGPERAQSILDNQFYQTVATSLAGTQEYMAMEKLGQLLSQDRWDLIVVDTPPSRNALDFLDAPKRLGSFMDSRLWRLLLAITGVMGLAMKALSTVLGSQMLADAAAFVQSLDAGGFREKADRTYALLKRRGTQFVVVSAAEPDALREASFFVDRLSQESMPLAGLVFNRTHPMLCALPIERAIDAAETLDAETSLAAAVLRIHAERGQTAKREIRLLSRFTGANPTVPVVGVPSLPFDVSDLEALRALADQLTT 6bs3 B 2.30 BS02 CA B 1 L165 D166 P168 K169 L161 D162 P164 K165 PKTLDMGAILADTSNRVVVCCGAGGVGKTTTAAALALRAAEYGRTVVVLTIDPAKRLAQALGINDLGNTPQRVPLAPEVPGELHAMMLDMRRTFDEMVMQYSGPERAQSILDNQFYQTVATSLAGTQEYMAMEKLGQLLSQDRWDLIVVDTPPSRNALDFLDAPKRLGSFMDSRLWRLLLAITGVMGLAMKALSTVLGSQMLADAAAFVQSLDAGGFREKADRTYALLKRRGTQFVVVSAAEPDALREASFFVDRLSQESMPLAGLVFNRTHPMLCALPIERAIDAAETLDAETSLAAAVLRIHAERGQTAKREIRLLSRFTGANPTVPVVGVPSLPFDVSDLEALRALADQLTT 6bs3 B 2.30 BS03 MG B 1 T33 D56 T29 D52 PKTLDMGAILADTSNRVVVCCGAGGVGKTTTAAALALRAAEYGRTVVVLTIDPAKRLAQALGINDLGNTPQRVPLAPEVPGELHAMMLDMRRTFDEMVMQYSGPERAQSILDNQFYQTVATSLAGTQEYMAMEKLGQLLSQDRWDLIVVDTPPSRNALDFLDAPKRLGSFMDSRLWRLLLAITGVMGLAMKALSTVLGSQMLADAAAFVQSLDAGGFREKADRTYALLKRRGTQFVVVSAAEPDALREASFFVDRLSQESMPLAGLVFNRTHPMLCALPIERAIDAAETLDAETSLAAAVLRIHAERGQTAKREIRLLSRFTGANPTVPVVGVPSLPFDVSDLEALRALADQLTT 6bs4 A 2.50 BS01 AGS A 1 G30 G31 T32 G33 K34 S35 T36 R60 N240 R241 P316 T317 V318 V322 G20 G21 T22 G23 K24 S25 T26 R50 N230 R231 P306 T307 V308 V312 P9WKX5 SVGWPSRLSGVRLHLVTGKGGTGKSTIAAALALTLAAGGRKVLLVEVEGRQGIAQLFDVPPLPYQELKIATAERGGQVNALAIDIEAAFLEYLDMFYNLGIAGRAMRRIGAVEFATTIAPGLRDVLLTGKIKETVVRLDKNKLPVYDAIVVDAPPTGRIARFLDVTKAVSDLAKGGPVHAQSEGVVKLLHSNQTAIHLVTLLEALPVQETLEAIEELAQMELPIGSVIVNRNIPAHLEPQDLAKAAEGEVDADSVRAGLLTAGVKLPDADFAGLLTETIQHATRITARAEIAQQLDALQVPRLELPTVSDGVDLGSLYELSESLAQQGVR 6bs4 B 2.50 BS01 AGS A 1 R159 D258 R155 D244 PKTLDMGAILADTSNRVVVCCGAGGVGKTTTAAALALRAAEYGRTVVVLTIDPAKRLAQALGINDLGNTPQRVPLAPEVPGELHAMMLDMRRTFDEMVMQYSGPERAQSILDNQFYQTVATSLAGTQEYMAMEKLGQLLSQDRWDLIVVDTPPSRNALDFLDAPKRLGSFMDSRLWRLLLAITGVMGLAMKALSTVLGSQMLADAAAFVQSLDAGGFREKADRTYALLKRRGTQFVVVSAAEPDALREASFFVDRLSQESMPLAGLVFNRTHPMLCALPIERAIDAAETLDAETSLAAAVLRIHAERGQTAKREIRLLSRFTGANPTVPVVGVPSLPFDVSDLEALRALADQLTT 6bs5 A 3.10 BS01 ANP A 1 G30 G31 G33 K34 S35 T36 R60 N240 R241 P316 T317 V318 V322 G20 G21 G23 K24 S25 T26 R50 N230 R231 P306 T307 V308 V312 P9WKX5 SVGWPSRLSGVRLHLVTGKGGTGKSTIAAALALTLAAGGRKVLLVEVEGRQGIAQLFDVPPLPYQELKIATAERGGQVNALAIDIEAAFLEYLDMFYNLGIAGRAMRRIGAVEFATTIAPGLRDVLLTGKIKETVVRLDKNKLPVYDAIVVDAPPTGRIARFLDVTKAVSDLAKGGPVHAQSEGVVKLLHSNQTAIHLVTLLEALPVQETLEAIEELAQMELPIGSVIVNRNIPAHLEPQDLAKAAEGEVDADSVRAGLLTAGVKLPDADFAGLLTETIQHATRITARAEIAQQLDALQVPRLELPTVSDGVDLGSLYELSESLAQQGVR 6bs5 A 3.10 BS02 MG A 1 S35 R60 S25 R50 P9WKX5 SVGWPSRLSGVRLHLVTGKGGTGKSTIAAALALTLAAGGRKVLLVEVEGRQGIAQLFDVPPLPYQELKIATAERGGQVNALAIDIEAAFLEYLDMFYNLGIAGRAMRRIGAVEFATTIAPGLRDVLLTGKIKETVVRLDKNKLPVYDAIVVDAPPTGRIARFLDVTKAVSDLAKGGPVHAQSEGVVKLLHSNQTAIHLVTLLEALPVQETLEAIEELAQMELPIGSVIVNRNIPAHLEPQDLAKAAEGEVDADSVRAGLLTAGVKLPDADFAGLLTETIQHATRITARAEIAQQLDALQVPRLELPTVSDGVDLGSLYELSESLAQQGVR 6d73 B 3.80 BS01 CA B 1 E857 Q860 N883 D886 R925 E712 Q715 N734 D737 R776 LASWIKENIKKKEQWDKHRHVRETPTDAFGDISFGGLGQKTGKYVRVSSDTSCENLYQLMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAVRDYTLSSGSMEGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDGTQGHYGVEIELRARLEKLISKLSLGGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIAHVASVPVSKVTMALINRLLKRFFMQEYKNFTELQIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEESQWTSSDLHPAMFSALVGDKPEFVRLLLENGVCVREFLEREETLCELYSHLPSCFFLRKLAKRVQEPLPGSRKVCLSHVSEEVRHLLGSFTQPLYIASRYDTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQESGEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYTGFLTFRRDEDIQRQAERTEQQKNCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQTSPSWRELLLYVWLTSLVCEEIRQLYHDGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQASDTVFYIGKVILCIDFIIFCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILIENEERLNWIIRGAVYEPYITIFGNFPTNIDNTLFDISSCSVNASDPLKPKCPMLNADNTPVFPEWLTIMMLCVYLLFANILLLNLLIAIFNYTFQEVQDNTDTIWKFQRYELIKEYHSRPALPPPFILLSHLILFIRGVFLRHKNFRQELEQTEEEELLSWEAYMKDNYLASTRQDESQSVEHRIHDTAEKVGAMSELLEREQEMVGGGGGGGGGGGGGGGGGGGGGGEEAPHMFARQLQYPDSTVRRFPVPEEKVSWEVNFSPYQPPVYNQQDKHRNPGGRTGIRGKGALNTLGPNHILHPIFTRWRDAEHKVLEFLAVWEDAEKRWALLGGPAQPDLAQVLERILGKKLKTLLKAGEEVYKGYVDDSRNTDNAWVETSIITLHTPLMADLNHMVESSLSSHQPLQWREVSSDACRCSYQREALRQIAHHH 6d73 A 3.80 BS01 CA A 1 E857 Q860 N883 R925 E704 Q707 N730 R772 LASWIKENIKKKEWDKHRHVRETPTDAFGDISFGGLGQKTGKYVRVSSDTSCENLYQLMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAVRDYTLSSGSMEGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDGTQGHYGVEIELRARLEKLISKLSLGNRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIAHVASVPVSKVTMALINRLLKRFFMQEYKNFTELQIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEESQWTSSDLHPAMFSALVGDKPEFVRLLLENGVCVREFLEREETLCELYSHLPSCFFLRKLAKRVQCLSHVSEEVRHLLGSFTQPLYIASRYKDTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQESGEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYTGFLTFRRDEDIQRQAERTEQCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQTSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQASDTVFYIGKVILCIDFIIFCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILIENEERLNWIIRGAVYEPYITIFGNFPTNIDNTLFDISSCSVNASDPLKPKCPMLNADNTPVFPEWLTIMMLCVYLLFANILLLNLLIAIFNYTFQEVQDNTDTIWKFQRYELIKEYHSRPALPPPFILLSHLILFIRGVFLRHKNFRQELEQTEEEELLSWEAYMKDNYLASTRQDESQSVEHRIHDTAEKVGAMSELLEREQEMVGGGGGGGGGGGGGGGGGGGGGGDEEAPHMFARQLQYPDSTVRRFPVPEEKVSWEVNFSPYQPPVYNQKHRNPGGRTGIRGKGALNTLGPNHILHPIFTRWRDKVLEFLAVWRWALLGGPALAQVLERILGKKLNEGEEVYKGYVDDSRNTDNAWVETSIITLHCDKNTMADLNHMVELQWREVSSDACRCSYQREALRQIA 6d99 A 2.15 BS02 UD2 A 1 F98 F153 I154 Y157 T158 Q161 Y187 N278 N280 R288 Y326 Y364 D366 F97 F152 I153 Y156 T157 Q160 Y186 N277 N279 R287 Y325 Y363 D365 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRYNFDNRYFNDTYEGLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNPEAPVVYTGPLDRYFDYSEGHLGWRTLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRHPKDKTVIMKEYSRFAEEGDEPYYPINTPSDREMLFKYRELADAETESGKVYFGGRLGTYQYLDMHMAIASALSMFDNKLVDALK 6d9b A 2.20 BS02 UPG A 1 H64 F98 F153 I154 Y157 T158 Q161 Y187 F188 N278 N280 R288 D366 H63 F97 F152 I153 Y156 T157 Q160 Y186 F187 N277 N279 R287 D365 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRYNFDNRYFNDTYEGLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNPEAPVVYTGPLDRYFDYSEGHLGWRTLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRHPKDKTVIMKEYSRFAEEGDEPYYPINTPSDREMLFKYRELADAETESGKVYFGGRLGTYQYLDMHMAIASALSMFDNKLVDALK 6d9c A 3.05 BS01 FDA A 1 V9 G10 S11 G12 L13 F14 V33 E34 K35 R36 G41 N42 Y58 G59 A60 H61 L62 T219 D220 W221 F222 P242 Y326 G357 R358 Y364 L365 D366 M367 V8 G9 S10 G11 L12 F13 V32 E33 K34 R35 G40 N41 Y57 G58 A59 H60 L61 T218 D219 W220 F221 P241 Y325 G356 R357 Y363 L364 D365 M366 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRYNFDNRYFNDTYEGLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNPEAPVVYTGPLDRYFDYSEGHLGWRTLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRHPKDKTVIMKEYSRFAEEGDEPYYPINTPSDREMLFKYRELADAETESGKVYFGGRLGTYQYLDMHMAIASALSMFDNKLVDALK 6dcm A 1.03 BS01 ACA A 1 D54 D56 W61 F63 R70 W71 D59 D61 W66 F68 R75 W76 3.4.21.7 EFSEECMHGSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDNDPQGPWCFTTDPNKRWEYCDIPRCA 6dcu A 2.95 BS01 NZA A 1 I262 I281 G284 C285 R288 I341 S342 M364 I57 I66 G69 C70 R73 I126 S127 M149 P37231 PESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLL 6dcu B 2.95 BS01 NZA B 1 I281 G284 C285 R288 I326 M329 L330 V339 I341 M348 F363 M364 I59 G62 C63 R66 I104 M107 L108 V117 I119 M126 F141 M142 P37231 PESADLRALAKHLYDSYIKSFPLTKAKARAILTGKSPFVIYDMNSLMMGEDKIEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLL 6ddn A 2.30 BS01 SO4 A 1 Y63 A64 G93 S95 S114 S179 G180 S181 S221 G222 Y240 Y9 A10 G39 S41 S60 S125 G126 S127 S167 G168 Y186 P71744 HTSITLVAYAVPEPGWSAVIPAFNASEQGRGVQVITSYGASADQSRGVADGKPADLVNFSVEPDIARLVKAGKVDKDWDADATKGIPFGSVVTFVVRAGNPKNIRDWDDLLRPGIEVITPSPLSSGSAKWNLLAPYAAKSDGGRNNQAGIDFVNTLVNEHVKLRPGSGREATDVFVQGSGDVLISYENEAIATERAGKPVQHVTPPQTFKIENPLAVVATSTHLGAATAFRNFQYTVQAQKLWAQAGFRPVDPAVAADFADLFPVPAKLWTIADLGGWGSVDPQLFD 6ddn A 2.30 BS02 SO4 A 2 T56 H277 G279 A280 T2 H223 G225 A226 P71744 HTSITLVAYAVPEPGWSAVIPAFNASEQGRGVQVITSYGASADQSRGVADGKPADLVNFSVEPDIARLVKAGKVDKDWDADATKGIPFGSVVTFVVRAGNPKNIRDWDDLLRPGIEVITPSPLSSGSAKWNLLAPYAAKSDGGRNNQAGIDFVNTLVNEHVKLRPGSGREATDVFVQGSGDVLISYENEAIATERAGKPVQHVTPPQTFKIENPLAVVATSTHLGAATAFRNFQYTVQAQKLWAQAGFRPVDPAVAADFADLFPVPAKLWTIADLGGWGSVDPQLFD 6ddn A 2.30 BS03 SO4 A 3 D160 W161 P260 Q261 D106 W107 P206 Q207 P71744 HTSITLVAYAVPEPGWSAVIPAFNASEQGRGVQVITSYGASADQSRGVADGKPADLVNFSVEPDIARLVKAGKVDKDWDADATKGIPFGSVVTFVVRAGNPKNIRDWDDLLRPGIEVITPSPLSSGSAKWNLLAPYAAKSDGGRNNQAGIDFVNTLVNEHVKLRPGSGREATDVFVQGSGDVLISYENEAIATERAGKPVQHVTPPQTFKIENPLAVVATSTHLGAATAFRNFQYTVQAQKLWAQAGFRPVDPAVAADFADLFPVPAKLWTIADLGGWGSVDPQLFD 6ddn B 2.30 BS04 SO4 B 4 D109 S275 T276 D55 S221 T222 P71744 HTSITLVAYAVPEPGWSAVIPAFNASEQGRGVQVITSYGASADQSRGVADGKPADLVNFSVEPDIARLVKAGKVDKDWDADATKGIPFGSVVTFVVRAGNPKNIRDWDDLLRPGIEVITPSPLSSGSAKWNLLAPYAAKSDGGRNNQAGIDFVNTLVNEHVKLRPGSGREATDVFVQGSGDVLISYENEAIATERAGKPVQHVTPPQTFKIENPLAVVATSTHLGAATAFRNFQYTVQAQKLWAQAGFRPVDPAVAADFADLFPVPAKLWTIADLGGWGSVDPQLFD 6de6 A 2.10 BS01 ADP A 1 V393 G394 G396 P397 A398 A416 E417 A418 T419 G424 R425 S461 R462 L463 A479 T480 G481 G650 D651 A661 V390 G391 G393 P394 A395 A413 E414 A415 T416 G421 R422 S458 R459 L460 A476 T477 G478 G647 D648 A658 Q60I59 NKYDILFEPVRIGPHIAKNRFYQVPHCNGGGYRDPSAAAAMRGIKSEGGWGVIFTEQTEMHHTSEITPFIELRLWEDKDIPGLRRMSDAMKVHGALAGIQLAYSGINGPNFYTKEVPLAPSALPIRTFTNDPVQARALDKQDIKNLRRWFVNAAKRSKIAGFDLICLYGAHGFGIFQHFLSRATNQRTDEYGGSLENRSRFAREVVEDIKEAVGDTTAITMRVSLDETIGELGFSNAEVREFVEMNANLPDLWDLAQGTWEDCSGPSRFKEEGAQEILVKGIRELSSKPVVGVGRFTSPDVMARMVRQGVLDFIGCARPSIADPFLPKKIEEGRIEDIRECIGCNICITGDMTMSISRCTQNPTFMEEWRKGWHPERMNAKGDSNTVLVVGAGPAGLEATRALSLRGYDVTLAEATTTLGGRVARERLLPGLSAWGRVVDYRQYQISQRTNVETYFDSRLTAEDVLGFGFEHVAIATGSHWRRDGVARQHVVPMPIDPSMTVWTPDDIMAKVHPENLSGKTVVVYDDDHYYMGGVMAEVMAKAGAKVILVTSSAYVSDWTRNTLEQGAIHVRLDDLGVDIRLNRGVTAIRAGEVETNCVYTGKRSAIGCDAVLMVASRTSEDQLFNDLIARQGDWPDAGIKSVKIIGDAAAPAPIAWATYAGHRYARELDTPDIGDDLPFRREVTQLEP 6de6 A 2.10 BS02 FMN A 1 V27 P28 H29 C30 Q60 Q103 Y171 H174 R225 W263 C266 S267 V296 R298 C319 A320 R321 P322 C350 I351 V24 P25 H26 C27 Q57 Q100 Y168 H171 R222 W260 C263 S264 V293 R295 C316 A317 R318 P319 C347 I348 Q60I59 NKYDILFEPVRIGPHIAKNRFYQVPHCNGGGYRDPSAAAAMRGIKSEGGWGVIFTEQTEMHHTSEITPFIELRLWEDKDIPGLRRMSDAMKVHGALAGIQLAYSGINGPNFYTKEVPLAPSALPIRTFTNDPVQARALDKQDIKNLRRWFVNAAKRSKIAGFDLICLYGAHGFGIFQHFLSRATNQRTDEYGGSLENRSRFAREVVEDIKEAVGDTTAITMRVSLDETIGELGFSNAEVREFVEMNANLPDLWDLAQGTWEDCSGPSRFKEEGAQEILVKGIRELSSKPVVGVGRFTSPDVMARMVRQGVLDFIGCARPSIADPFLPKKIEEGRIEDIRECIGCNICITGDMTMSISRCTQNPTFMEEWRKGWHPERMNAKGDSNTVLVVGAGPAGLEATRALSLRGYDVTLAEATTTLGGRVARERLLPGLSAWGRVVDYRQYQISQRTNVETYFDSRLTAEDVLGFGFEHVAIATGSHWRRDGVARQHVVPMPIDPSMTVWTPDDIMAKVHPENLSGKTVVVYDDDHYYMGGVMAEVMAKAGAKVILVTSSAYVSDWTRNTLEQGAIHVRLDDLGVDIRLNRGVTAIRAGEVETNCVYTGKRSAIGCDAVLMVASRTSEDQLFNDLIARQGDWPDAGIKSVKIIGDAAAPAPIAWATYAGHRYARELDTPDIGDDLPFRREVTQLEP 6de6 A 2.10 BS03 SF4 A 1 R321 I324 C344 I345 G346 C347 N348 I349 C350 C362 T363 Q364 R318 I321 C341 I342 G343 C344 N345 I346 C347 C359 T360 Q361 Q60I59 NKYDILFEPVRIGPHIAKNRFYQVPHCNGGGYRDPSAAAAMRGIKSEGGWGVIFTEQTEMHHTSEITPFIELRLWEDKDIPGLRRMSDAMKVHGALAGIQLAYSGINGPNFYTKEVPLAPSALPIRTFTNDPVQARALDKQDIKNLRRWFVNAAKRSKIAGFDLICLYGAHGFGIFQHFLSRATNQRTDEYGGSLENRSRFAREVVEDIKEAVGDTTAITMRVSLDETIGELGFSNAEVREFVEMNANLPDLWDLAQGTWEDCSGPSRFKEEGAQEILVKGIRELSSKPVVGVGRFTSPDVMARMVRQGVLDFIGCARPSIADPFLPKKIEEGRIEDIRECIGCNICITGDMTMSISRCTQNPTFMEEWRKGWHPERMNAKGDSNTVLVVGAGPAGLEATRALSLRGYDVTLAEATTTLGGRVARERLLPGLSAWGRVVDYRQYQISQRTNVETYFDSRLTAEDVLGFGFEHVAIATGSHWRRDGVARQHVVPMPIDPSMTVWTPDDIMAKVHPENLSGKTVVVYDDDHYYMGGVMAEVMAKAGAKVILVTSSAYVSDWTRNTLEQGAIHVRLDDLGVDIRLNRGVTAIRAGEVETNCVYTGKRSAIGCDAVLMVASRTSEDQLFNDLIARQGDWPDAGIKSVKIIGDAAAPAPIAWATYAGHRYARELDTPDIGDDLPFRREVTQLEP 6de6 B 2.10 BS01 ADP B 1 V393 G394 G396 P397 A398 A416 E417 A418 T419 G424 R425 S461 R462 L463 A479 T480 G481 G650 D651 A661 V353 G354 G356 P357 A358 A376 E377 A378 T379 G384 R385 S421 R422 L423 A439 T440 G441 G610 D611 A621 Q60I59 RDNKYDILFEPVRIGPHIAKNRFYQVPHCNGGGYRDPSAAAAMRGIKSEGGWGVIFTEQTEMHHTSEITPFIELRLWEDKDIPGLRRMSDAMKVHGALAGIQLAYSGINGPNFYTKEVPLAPSALPIRTFTNDPVQARALDKQDIKNLRRWFVNAAKRSKIAGFDLICLYGAHGFGIFQHFLSRATNQRTDEYGGSLENRSRFAREVVEDIKEAVGDTTAITMRVSREFVEMNANLPDLWDLAVKGIRELSSKPVVGVGRSPDVMARMVRQGVLDFIGCARPSIADPFLPKKIEEGRIEDIRECIGCNICITGDMTMSISRCTQNPTFMEEWRKGWHPERMNAKGDSNTVLVVGAGPAGLEATRALSLRGYDVTLAEATTTLGGRVARERLLPGLSAWGRVVDYRQYQISQRTNVETYFDSRLTAEDVLGFGFEHVAIATGSHWRRDGVARQHVVPMPIDPSMTVWTPDDIMAKVHPENLSGKTVVVYDDDHYYMGGVMAEVMAKAGAKVILVTSSAYVSDWTRNTLEQGAIHVRLDDLGVDIRLNRGVTAIRAGEVETNCVYTGKRSAIGCDAVLMVASRTSEDQLFNDLIARQGDWPDAGIKSVKIIGDAAAPAPIAWATYAGHRYARELDTPDIGDDLPFRREVTQLEP 6de6 B 2.10 BS02 FMN B 1 V27 P28 H29 C30 Q60 Q103 Y171 H174 R225 V296 R298 C319 A320 R321 P322 C350 I351 V26 P27 H28 C29 Q59 Q102 Y170 H173 R224 V258 R260 C279 A280 R281 P282 C310 I311 Q60I59 RDNKYDILFEPVRIGPHIAKNRFYQVPHCNGGGYRDPSAAAAMRGIKSEGGWGVIFTEQTEMHHTSEITPFIELRLWEDKDIPGLRRMSDAMKVHGALAGIQLAYSGINGPNFYTKEVPLAPSALPIRTFTNDPVQARALDKQDIKNLRRWFVNAAKRSKIAGFDLICLYGAHGFGIFQHFLSRATNQRTDEYGGSLENRSRFAREVVEDIKEAVGDTTAITMRVSREFVEMNANLPDLWDLAVKGIRELSSKPVVGVGRSPDVMARMVRQGVLDFIGCARPSIADPFLPKKIEEGRIEDIRECIGCNICITGDMTMSISRCTQNPTFMEEWRKGWHPERMNAKGDSNTVLVVGAGPAGLEATRALSLRGYDVTLAEATTTLGGRVARERLLPGLSAWGRVVDYRQYQISQRTNVETYFDSRLTAEDVLGFGFEHVAIATGSHWRRDGVARQHVVPMPIDPSMTVWTPDDIMAKVHPENLSGKTVVVYDDDHYYMGGVMAEVMAKAGAKVILVTSSAYVSDWTRNTLEQGAIHVRLDDLGVDIRLNRGVTAIRAGEVETNCVYTGKRSAIGCDAVLMVASRTSEDQLFNDLIARQGDWPDAGIKSVKIIGDAAAPAPIAWATYAGHRYARELDTPDIGDDLPFRREVTQLEP 6de6 B 2.10 BS03 SF4 B 1 R321 I324 C344 I345 G346 C347 N348 I349 C350 R361 C362 T363 R281 I284 C304 I305 G306 C307 N308 I309 C310 R321 C322 T323 Q60I59 RDNKYDILFEPVRIGPHIAKNRFYQVPHCNGGGYRDPSAAAAMRGIKSEGGWGVIFTEQTEMHHTSEITPFIELRLWEDKDIPGLRRMSDAMKVHGALAGIQLAYSGINGPNFYTKEVPLAPSALPIRTFTNDPVQARALDKQDIKNLRRWFVNAAKRSKIAGFDLICLYGAHGFGIFQHFLSRATNQRTDEYGGSLENRSRFAREVVEDIKEAVGDTTAITMRVSREFVEMNANLPDLWDLAVKGIRELSSKPVVGVGRSPDVMARMVRQGVLDFIGCARPSIADPFLPKKIEEGRIEDIRECIGCNICITGDMTMSISRCTQNPTFMEEWRKGWHPERMNAKGDSNTVLVVGAGPAGLEATRALSLRGYDVTLAEATTTLGGRVARERLLPGLSAWGRVVDYRQYQISQRTNVETYFDSRLTAEDVLGFGFEHVAIATGSHWRRDGVARQHVVPMPIDPSMTVWTPDDIMAKVHPENLSGKTVVVYDDDHYYMGGVMAEVMAKAGAKVILVTSSAYVSDWTRNTLEQGAIHVRLDDLGVDIRLNRGVTAIRAGEVETNCVYTGKRSAIGCDAVLMVASRTSEDQLFNDLIARQGDWPDAGIKSVKIIGDAAAPAPIAWATYAGHRYARELDTPDIGDDLPFRREVTQLEP 6de9 A 1.95 BS01 FES A 1 C72 R73 C74 S77 C83 D84 G85 A86 H87 G99 P100 C42 R43 C44 S47 C53 D54 G55 A56 H57 G69 P70 Q9NZ45 TKRFYVKDHRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKK 6de9 A 1.95 BS02 FUN A 1 V70 H87 I102 V40 H57 I72 Q9NZ45 TKRFYVKDHRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKK 6dfm A 2.14 BS01 3BH A 1 Y39 G227 G255 E293 K296 R297 S300 G364 S365 R367 I368 Y14 G202 G230 E268 K271 R272 S275 G339 S340 R342 I343 3.6.4.10 P11021 DVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSG 6dfo A 2.54 BS01 GBA A 1 Y39 I61 G227 G255 E293 K296 R297 S300 G364 S365 R367 I368 Y14 I36 G200 G228 E266 K269 R270 S273 G337 S338 R340 I341 3.6.4.10 P11021 DVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSG 6dql A 3.30 BS01 III C 1 R188 N192 Q199 M267 F268 R133 N137 Q144 M212 F213 D3KVD8 NVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSKSTKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESCFIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQLNDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIKHKLSLE 6e60 A 1.50 BS01 MG A 1 R492 D555 E557 R472 D535 E537 A7LY27 31062073 HMDEYMENMNTDPSKAATIDPNAQLTTAQLQTYGDLSMMEIYRNYHYAFTQQLMGCWNTTNYGGRHTLDNNEMSRIWTSFYTQSLKNIIDAQYRTAEDAEKVNINSVLRIYRVYLMSIITDTYGDAPFSEAGLGFLEGKFNPKYDKQEDIYNAFFLELEDAVNKIDPTKDKVTGDLIYAGDVTKWQQLANSLRLRFAMRISSVNPTKAQTEFENALAANGGVITDASSDALIKYMTIAFSFGQEAYSDYRGNSLSQLLFGNDPANNPSYLCSTFFNQLYNSGDPRTFKISRCYYDGLMSATSPDNRVDITQEMIEKGIAFSPRDPGAYSWEPWPTGYDSDICAELAVNNPSVTATMAREVEPKLANNFLKSDNPGVVMTSAEVKFLMAEATVKKWNVGSVSAEDLYKQGVRAAIDFLTDNYGCTATTDAEFDAFIQDKGAFGHTDNQKLEAINTQAWILHFTNPAECWANVRRSGYPKLKSPAEYGFGQYLTGGTEIPVRLCYPVLESSYNKKSYNEAIERMGGTDNWHSLLWWDTEN 6e61 A 2.51 BS01 BGC A 1 E60 R95 Q263 E21 R56 Q224 A7LY27 31062073 DPNAQLTTAQLQTYGDLSMMEIYRNYHYAFTQQLMGCWNTTNYGGRHTLDNNEMSRIWTSFYTQSLKNIIDAQYRTAEDAEKVNINSVLRIYRVYLMSIITDTYGDAPFSEAGLGFLEGKFNPKYDKQEDIYNAFFLELEDAVNKIDPTKDKVTGDLIYAGDVTKWQQLANSLRLRFAMRISSVNPTKAQTEFENALAANGGVITDASSDALIKYMTIAFSFGQEAYSDYRGNSLSQLLFGNDPANNPSYLCSTFFNQLYNSGDPRTFKISRCYYDGLMSATSPDNRVDITQEMIEKGIAFSPRDPGAYSWEPWPTGYDSDICAELAVNNPSVTATMAREVEPKLANNFLKSDNPGVVMTSAEVKFLMAEATVKKWNVGSVSAEDLYKQGVRAAIDFLTDNYGCTATTDAEFDAFIQDKGAFGHTDNQKLEAINTQAWILHFTNPAECWANVRRSGYPKLKSPAEYGFGQYLTGGTEIPVRLCYPVLESSYNKKSYNEAIERMGGTDNWHSLLWWDTEN 6e61 A 2.51 BS02 BGC A 2 E60 R63 N78 N281 E21 R24 N39 N242 A7LY27 31062073 DPNAQLTTAQLQTYGDLSMMEIYRNYHYAFTQQLMGCWNTTNYGGRHTLDNNEMSRIWTSFYTQSLKNIIDAQYRTAEDAEKVNINSVLRIYRVYLMSIITDTYGDAPFSEAGLGFLEGKFNPKYDKQEDIYNAFFLELEDAVNKIDPTKDKVTGDLIYAGDVTKWQQLANSLRLRFAMRISSVNPTKAQTEFENALAANGGVITDASSDALIKYMTIAFSFGQEAYSDYRGNSLSQLLFGNDPANNPSYLCSTFFNQLYNSGDPRTFKISRCYYDGLMSATSPDNRVDITQEMIEKGIAFSPRDPGAYSWEPWPTGYDSDICAELAVNNPSVTATMAREVEPKLANNFLKSDNPGVVMTSAEVKFLMAEATVKKWNVGSVSAEDLYKQGVRAAIDFLTDNYGCTATTDAEFDAFIQDKGAFGHTDNQKLEAINTQAWILHFTNPAECWANVRRSGYPKLKSPAEYGFGQYLTGGTEIPVRLCYPVLESSYNKKSYNEAIERMGGTDNWHSLLWWDTEN 6e61 A 2.51 BS03 BGC A 3 W77 N281 D282 N286 W38 N242 D243 N247 A7LY27 31062073 DPNAQLTTAQLQTYGDLSMMEIYRNYHYAFTQQLMGCWNTTNYGGRHTLDNNEMSRIWTSFYTQSLKNIIDAQYRTAEDAEKVNINSVLRIYRVYLMSIITDTYGDAPFSEAGLGFLEGKFNPKYDKQEDIYNAFFLELEDAVNKIDPTKDKVTGDLIYAGDVTKWQQLANSLRLRFAMRISSVNPTKAQTEFENALAANGGVITDASSDALIKYMTIAFSFGQEAYSDYRGNSLSQLLFGNDPANNPSYLCSTFFNQLYNSGDPRTFKISRCYYDGLMSATSPDNRVDITQEMIEKGIAFSPRDPGAYSWEPWPTGYDSDICAELAVNNPSVTATMAREVEPKLANNFLKSDNPGVVMTSAEVKFLMAEATVKKWNVGSVSAEDLYKQGVRAAIDFLTDNYGCTATTDAEFDAFIQDKGAFGHTDNQKLEAINTQAWILHFTNPAECWANVRRSGYPKLKSPAEYGFGQYLTGGTEIPVRLCYPVLESSYNKKSYNEAIERMGGTDNWHSLLWWDTEN 6e61 A 2.51 BS04 BGC A 4 W77 N286 W350 W38 N247 W311 A7LY27 31062073 DPNAQLTTAQLQTYGDLSMMEIYRNYHYAFTQQLMGCWNTTNYGGRHTLDNNEMSRIWTSFYTQSLKNIIDAQYRTAEDAEKVNINSVLRIYRVYLMSIITDTYGDAPFSEAGLGFLEGKFNPKYDKQEDIYNAFFLELEDAVNKIDPTKDKVTGDLIYAGDVTKWQQLANSLRLRFAMRISSVNPTKAQTEFENALAANGGVITDASSDALIKYMTIAFSFGQEAYSDYRGNSLSQLLFGNDPANNPSYLCSTFFNQLYNSGDPRTFKISRCYYDGLMSATSPDNRVDITQEMIEKGIAFSPRDPGAYSWEPWPTGYDSDICAELAVNNPSVTATMAREVEPKLANNFLKSDNPGVVMTSAEVKFLMAEATVKKWNVGSVSAEDLYKQGVRAAIDFLTDNYGCTATTDAEFDAFIQDKGAFGHTDNQKLEAINTQAWILHFTNPAECWANVRRSGYPKLKSPAEYGFGQYLTGGTEIPVRLCYPVLESSYNKKSYNEAIERMGGTDNWHSLLWWDTEN 6e61 B 2.51 BS01 BGC B 1 E60 R95 E21 R56 A7LY27 31062073 DPNAQLTTAQLQTYGDLSMMEIYRNYHYAFTQQLMGCWNTTNYGGRHTLDNNEMSRIWTSFYTQSLKNIIDAQYRTAEDAEKVNINSVLRIYRVYLMSIITDTYGDAPFSEAGLGFLEGKFNPKYDKQEDIYNAFFLELEDAVNKIDPTKDKVTGDLIYAGDVTKWQQLANSLRLRFAMRISSVNPTKAQTEFENALAANGGVITDASSDALIKYMTIAFSFGQEAYSDYRGNSLSQLLFGNDPANNPSYLCSTFFNQLYNSGDPRTFKISRCYYDGLMSATSPDNRVDITQEMIEKGIAFSPRDPGAYSWEPWPTGYDSDICAELAVNNPSVTATMAREVEPKLANNFLKSDNPGVVMTSAEVKFLMAEATVKKWNVGSVSAEDLYKQGVRAAIDFLTDNYGCTATTDAEFDAFIQDKGAFGHTDNQKLEAINTQAWILHFTNPAECWANVRRSGYPKLKSPAEYGFGQYLTGGTEIPVRLCYPVLESSYNKKSYNEAIERMGGTDNWHSLLWWDTEN 6e61 B 2.51 BS03 BGC B 3 W77 D282 N286 W38 D243 N247 A7LY27 31062073 DPNAQLTTAQLQTYGDLSMMEIYRNYHYAFTQQLMGCWNTTNYGGRHTLDNNEMSRIWTSFYTQSLKNIIDAQYRTAEDAEKVNINSVLRIYRVYLMSIITDTYGDAPFSEAGLGFLEGKFNPKYDKQEDIYNAFFLELEDAVNKIDPTKDKVTGDLIYAGDVTKWQQLANSLRLRFAMRISSVNPTKAQTEFENALAANGGVITDASSDALIKYMTIAFSFGQEAYSDYRGNSLSQLLFGNDPANNPSYLCSTFFNQLYNSGDPRTFKISRCYYDGLMSATSPDNRVDITQEMIEKGIAFSPRDPGAYSWEPWPTGYDSDICAELAVNNPSVTATMAREVEPKLANNFLKSDNPGVVMTSAEVKFLMAEATVKKWNVGSVSAEDLYKQGVRAAIDFLTDNYGCTATTDAEFDAFIQDKGAFGHTDNQKLEAINTQAWILHFTNPAECWANVRRSGYPKLKSPAEYGFGQYLTGGTEIPVRLCYPVLESSYNKKSYNEAIERMGGTDNWHSLLWWDTEN 6e9b D 3.15 BS01 BGC D 1 Y371 W372 Y319 W320 A7LY28 31062073 NDDPHILAPVFPDRTNGQLATFANISRDANTTVIDGQEVESGTDSDKEINRSLKAGTYNLKETVKGKKTSREGVVNPLADDPQSKEVAFERIVSPGKTARLYGSNLQNVTAILLGGNTITDPTYVESADENYLEYTIPTGVSEGDYRIVLQDADGNQYGADMVKVTNASLVISGANRATANVDWTISGINLENIASLTIGGQTVSQFSNQSSTEITLTCPDLSDGSYTMTGKTRSGEAVQFLNDNITTTEQTVTVSTEITLWSGHHYVSWDKPDGDPNKTFGLIPMDVFAGITAGSTLKVVYSIEPTAEYHKMQLATGYWTGLASEMEFTENGEYTLILTQDMLNKIQAEAGFLCVGHGYYVDLVTVK 6e9b D 3.15 BS02 BGC D 2 W322 K331 W372 W270 K279 W320 A7LY28 31062073 NDDPHILAPVFPDRTNGQLATFANISRDANTTVIDGQEVESGTDSDKEINRSLKAGTYNLKETVKGKKTSREGVVNPLADDPQSKEVAFERIVSPGKTARLYGSNLQNVTAILLGGNTITDPTYVESADENYLEYTIPTGVSEGDYRIVLQDADGNQYGADMVKVTNASLVISGANRATANVDWTISGINLENIASLTIGGQTVSQFSNQSSTEITLTCPDLSDGSYTMTGKTRSGEAVQFLNDNITTTEQTVTVSTEITLWSGHHYVSWDKPDGDPNKTFGLIPMDVFAGITAGSTLKVVYSIEPTAEYHKMQLATGYWTGLASEMEFTENGEYTLILTQDMLNKIQAEAGFLCVGHGYYVDLVTVK 6e9b D 3.15 BS03 BGC D 3 W322 K364 W270 K312 A7LY28 31062073 NDDPHILAPVFPDRTNGQLATFANISRDANTTVIDGQEVESGTDSDKEINRSLKAGTYNLKETVKGKKTSREGVVNPLADDPQSKEVAFERIVSPGKTARLYGSNLQNVTAILLGGNTITDPTYVESADENYLEYTIPTGVSEGDYRIVLQDADGNQYGADMVKVTNASLVISGANRATANVDWTISGINLENIASLTIGGQTVSQFSNQSSTEITLTCPDLSDGSYTMTGKTRSGEAVQFLNDNITTTEQTVTVSTEITLWSGHHYVSWDKPDGDPNKTFGLIPMDVFAGITAGSTLKVVYSIEPTAEYHKMQLATGYWTGLASEMEFTENGEYTLILTQDMLNKIQAEAGFLCVGHGYYVDLVTVK 6e9b D 3.15 BS04 BGC D 4 Y362 K364 Y310 K312 A7LY28 31062073 NDDPHILAPVFPDRTNGQLATFANISRDANTTVIDGQEVESGTDSDKEINRSLKAGTYNLKETVKGKKTSREGVVNPLADDPQSKEVAFERIVSPGKTARLYGSNLQNVTAILLGGNTITDPTYVESADENYLEYTIPTGVSEGDYRIVLQDADGNQYGADMVKVTNASLVISGANRATANVDWTISGINLENIASLTIGGQTVSQFSNQSSTEITLTCPDLSDGSYTMTGKTRSGEAVQFLNDNITTTEQTVTVSTEITLWSGHHYVSWDKPDGDPNKTFGLIPMDVFAGITAGSTLKVVYSIEPTAEYHKMQLATGYWTGLASEMEFTENGEYTLILTQDMLNKIQAEAGFLCVGHGYYVDLVTVK 6ec0 A 2.98 BS01 CO A 1 Q249 D253 Q25 D29 H6VRG1 31036554 MNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQIS 6ec0 B 2.98 BS01 CO B 1 N212 D216 N18 D22 P13645 31036554 DYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRN 6gfe H 1.80 BS01 CA H 1 S33 D96 S33 D103 31023536 QVELQQSGPGLVKPSQTLSLTCAISGDSVSSRSASWSWIRQSPGRGLEWLGRTYYRSHWYYEYAQSVKSRITINPDTSKNQFSLQLNSVTPEDTAVYYCARMDVPSFRYFDVWGQGTLVTVSSASTKGPSVFPLAPCSSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLS 6gfe K 1.80 BS01 CA K 1 E430 A431 E412 A413 31023536 QVELQQSGPGLVKPSQTLSLTCAISGDSVSSRSASWSWIRQSPGRGLEWLGRTYYRSHWYYEYAQSVKSRITINPDTSKNQFSLQLNSVTPEDTAVYYCARMDVPSFRYFDVWGQGTLVTVSSASTKGPSVFPLAPCSSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLS 6gfe L 1.80 BS01 FUC H 1 R108 T109 R109 T110 31023536 DIVLTQSPATLSLSPGERATLSCRASQSVRSNYLAWYQQKPGQAPRLLIYGASNRATGVPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQISNSPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6gl4 A 1.95 BS02 BR A 1 T93 V95 R96 E145 T93 V95 R96 E145 P19491 31053408 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 6gl4 B 1.95 BS02 BR B 1 T93 V95 S142 T93 V95 S142 P19491 31053408 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 6gl4 B 1.95 BS03 NA B 1 R182 I200 E201 R203 K204 P205 C206 D207 T208 C261 R182 I200 E201 R203 K204 P205 C206 D207 T208 C261 P19491 31053408 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 6gr8 A 1.75 BS01 F8Z A 1 L49 G50 K51 G52 K53 F54 V57 A70 K72 L74 I79 L84 Q87 L88 E91 L104 L118 L120 E121 A123 E127 E170 L173 A183 D184 G186 L18 G19 K20 G21 K22 F23 V26 A39 K41 L43 I48 L53 Q56 L57 E60 L73 L87 L89 E90 A92 E96 E139 L142 A152 D153 G155 2.7.11.1 Q9UQB9 GANSRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSDKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPP 6gr9 A 2.25 BS01 VX6 A 1 L49 G50 F54 A70 K72 E121 Y122 A123 P124 G126 E127 L173 A183 L13 G14 F18 A34 K36 E85 Y86 A87 P88 G90 E91 L137 A147 2.7.11.1 Q9UQB9 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSDKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCA 6gra A 2.60 BS01 F8Z A 1 L139 K141 G142 K143 F144 V147 A160 K162 V174 L178 E181 L210 E211 A213 T217 E260 N261 L263 A273 D274 L14 K16 G17 K18 F19 V22 A35 K37 V49 L53 E56 L85 E86 A88 T92 E135 N136 L138 A148 D149 2.7.11.1 O14965 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 6h0u A 2.30 BS01 FKB A 1 I62 V70 A83 K85 V110 L132 D133 Y134 V135 P136 T138 R141 L188 C199 D200 I27 V35 A48 K50 V75 L97 D98 Y99 V100 P101 T103 R106 L153 C164 D165 2.7.11.26,2.7.11.1 P49841 30548443 KVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR 6h12 A 2.20 BS01 FJK A 1 Y70 Q74 W84 Y121 E199 W279 F330 F331 W432 I439 H440 Y442 Y67 Q71 W81 Y118 E196 W276 F327 F328 W429 I436 H437 Y439 3.1.1.7 P04058 30798053 SELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 6h12 B 2.20 BS01 FJK B 1 W84 Y121 W279 F284 D285 S286 F330 G335 W432 I439 H440 Y442 W81 Y118 W276 F281 D282 S283 F327 G332 W429 I436 H437 Y439 3.1.1.7 P04058 30798053 SELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 6h13 A 2.80 BS01 FJN A 1 W84 G118 Y121 E199 W279 L282 F284 D285 F330 F331 W432 H440 Y442 W81 G115 Y118 E196 W276 L279 F281 D282 F327 F328 W429 H437 Y439 3.1.1.7 P04058 30798053 SELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 6h14 A 1.86 BS01 FW8 A 1 W84 Y121 E199 W279 L282 F288 F290 F330 F331 Y334 W432 I439 H440 G441 Y442 W81 Y118 E196 W276 L279 F285 F287 F327 F328 Y331 W429 I436 H437 G438 Y439 3.1.1.7 P04058 30798053 SELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSSKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 6h59 A 1.80 BS01 MG A 1 D68 D89 D93 D56 D77 D81 2.7.8.11 P9WPG7 ARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMAI 6h59 A 1.80 BS03 FQT A 1 P30 D31 T34 W62 V65 D68 M69 D71 G72 A75 R76 G81 T82 G85 A86 D89 R152 P153 L156 P18 D19 T22 W50 V53 D56 M57 D59 G60 A63 R64 G69 T70 G73 A74 D77 R140 P141 L144 2.7.8.11 P9WPG7 ARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMAI 6h59 B 1.80 BS01 MG B 1 D68 D71 D54 D57 2.7.8.11 P9WPG7 ITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMA 6h59 B 1.80 BS03 FQT B 1 P30 D31 T34 V65 D68 M69 D71 G72 G81 T82 G85 A86 P16 D17 T20 V51 D54 M55 D57 G58 G67 T68 G71 A72 2.7.8.11 P9WPG7 ITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMA 6h5a A 1.88 BS03 FLC A 1 D68 D89 D93 R152 P153 D65 D86 D90 R149 P150 2.7.8.11 P9WPG7 LPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMA 6h5a A 1.88 BS04 FLC A 2 A90 S132 K135 R195 A87 S129 K132 R192 2.7.8.11 P9WPG7 LPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMA 6h5a B 1.88 BS03 FLC B 1 R94 S132 K135 E151 R152 R155 R195 R80 S118 K121 E137 R138 R141 R181 2.7.8.11 P9WPG7 ITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDRENLYFQ 6h9x A 2.10 BS01 SSA A 1 T237 E239 R268 E270 I282 R283 M284 F287 K289 E291 E355 I356 S357 S358 N389 G390 S391 A394 R397 T235 E237 R266 E268 I280 R281 M282 F285 K287 E289 E353 I354 S355 S356 N387 G388 S389 A392 R395 6.1.1.11 W9BNU9 31048140 MLDPNLLRTEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVQTENLQAERNSRSKSIGQAKARDIEPLRLEVNKLGEQLDAAKSELETLLAEIRDIALAIPNIPHDDVPVGRDENDNVEVSRWGTPRQFDFEVRDHVTLGEMHGGLDFAAAVKLTGSRFVVMKGQLARLHRALAQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKVALCTGDMGFSACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVALMENYQQADGRIEIPEVLRPYMRGLEYIG 6h9x A 2.10 BS02 CA A 1 D342 E355 S358 D340 E353 S356 6.1.1.11 W9BNU9 31048140 MLDPNLLRTEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVQTENLQAERNSRSKSIGQAKARDIEPLRLEVNKLGEQLDAAKSELETLLAEIRDIALAIPNIPHDDVPVGRDENDNVEVSRWGTPRQFDFEVRDHVTLGEMHGGLDFAAAVKLTGSRFVVMKGQLARLHRALAQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKVALCTGDMGFSACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVALMENYQQADGRIEIPEVLRPYMRGLEYIG 6h9x A 2.10 BS03 CA A 2 E239 S336 S360 V362 N389 E237 S334 S358 V360 N387 6.1.1.11 W9BNU9 31048140 MLDPNLLRTEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVQTENLQAERNSRSKSIGQAKARDIEPLRLEVNKLGEQLDAAKSELETLLAEIRDIALAIPNIPHDDVPVGRDENDNVEVSRWGTPRQFDFEVRDHVTLGEMHGGLDFAAAVKLTGSRFVVMKGQLARLHRALAQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKVALCTGDMGFSACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVALMENYQQADGRIEIPEVLRPYMRGLEYIG 6i2a A 1.75 BS01 III D 1 E127 F129 R133 K168 P169 E170 L198 C199 G200 T201 P202 E203 Y204 L205 E230 Y235 P236 F239 A240 D241 P243 I246 Y247 E130 F132 R136 K171 P172 E173 L201 C202 G203 T204 P205 E206 Y207 L208 E233 Y238 P239 F242 A243 D244 P246 I249 Y250 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 6i7n A 3.30 BS01 FAD A 1 G11 G13 S14 G15 V34 D35 A46 A47 G50 T51 C52 G56 C57 K60 G125 G127 A159 T160 G161 S178 R287 L294 D327 M333 L334 T335 P336 A338 G12 G14 S15 G16 V35 D36 A47 A48 G51 T52 C53 G57 C58 K61 G126 G128 A160 T161 G162 S179 R288 L295 D328 M334 L335 T336 P337 A339 1.8.1.12 A4HSF7 30983322 PMSRAYDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPLFAALGGTCVNVGCVPKKLMVTGAQYMDLIRESGGFGWEMDRESLCPNWKTLIAAKNKVVNSINESYKSMFADTEGLSFHMGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGSWPTRLGVPGDEFCITSNEAFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEVRKSLTKQLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEEDYDQVMLAIGRVPRSQALQLDKAGVRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFVETVFGGKPRATDHTKVACAVFSIPPIGTCGMTEEEAAKNYETVAVYASSFTPLMHNISGSKHKEFMIRIITNESNGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAEELCSMRTPAYFYESGKRVEKLSS 6i7n B 3.30 BS01 FAD B 1 G11 G13 G15 D35 A46 A47 G50 T51 C52 G56 C57 K60 G127 A159 T160 G161 Y198 R287 R290 L294 G326 D327 M333 L334 T335 P336 G11 G13 G15 D35 A46 A47 G50 T51 C52 G56 C57 K60 G127 A159 T160 G161 Y198 R287 R290 L294 G326 D327 M333 L334 T335 P336 1.8.1.12 A4HSF7 30983322 MSRAYDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPLFAALGGTCVNVGCVPKKLMVTGAQYMDLIRESGGFGWEMDRESLCPNWKTLIAAKNKVVNSINESYKSMFADTEGLSFHMGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGSWPTRLGVPGDEFCITSNEAFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEVRKSLTKQLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEEDYDQVMLAIGRVPRSQALQLDKAGVRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFVETVFGGKPRATDHTKVACAVFSIPPIGTCGMTEEEAAKNYETVAVYASSFTPLMHNISGSKHKEFMIRIITNESNGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAEELCSMRTPAYFYESGKRVEKLS 6i7n B 3.30 BS02 H6H B 1 L17 E18 Y110 M113 L17 E18 Y110 M113 1.8.1.12 A4HSF7 30983322 MSRAYDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPLFAALGGTCVNVGCVPKKLMVTGAQYMDLIRESGGFGWEMDRESLCPNWKTLIAAKNKVVNSINESYKSMFADTEGLSFHMGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGSWPTRLGVPGDEFCITSNEAFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEVRKSLTKQLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEEDYDQVMLAIGRVPRSQALQLDKAGVRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFVETVFGGKPRATDHTKVACAVFSIPPIGTCGMTEEEAAKNYETVAVYASSFTPLMHNISGSKHKEFMIRIITNESNGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAEELCSMRTPAYFYESGKRVEKLS 6ibv A 1.40 BS01 H9E A 1 L65 W93 H120 H122 D124 H189 C208 H250 L26 W50 H77 H79 D81 H146 C165 H207 3.5.2.6 C7C422 30996812 ETGDQRFGDLVFRQLAPNVWQHTSYLDGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR 6ibv B 1.40 BS01 H9E B 1 D66 W93 H120 H122 Q123 D124 H189 C208 H250 D28 W51 H78 H80 Q81 D82 H147 C166 H208 3.5.2.6 C7C422 30996812 METGDQRFGDLVFRQLAPNVWQHTSYLDGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR 6ic2 A 1.15 BS02 BBJ A 1 I91 Q92 H94 H96 H119 V121 F131 L198 T199 T200 P202 I89 Q90 H92 H94 H117 V119 F128 L195 T196 T197 P199 4.2.1.1 P00918 31038135 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 6idv A 2.40 BS01 SNN A 1 G61 H70 Y169 A170 H172 G173 G179 E212 A213 Q343 G11 H20 Y119 A120 H121 G122 G128 E161 A162 Q285 IGTRWAVLIAGSKGYHNYRHQADVCHMYQILRKGGVKDENIIVFMYDDIAYNESNPFPGIIINKPGGENVYKGVPKDYTGEDINNVNFLAAILGNKSAIIGGSGKVLDTSPNDHIFIYYAHGAPGKIGMPSKPYLYADDLVDTLKQKAATGTYKSMVFYVEACNAGSMFEGLLPEGTNIYAMAASNSTEGSWITYCPGTPDFPPEFDVCLGDLWSITFLEDCDAHNLRTETVHQQFELVKKKIAYASTVSQYGDIPISKDSLSVYMGTDPANDNRTFVPLKVIHQHDADLYHIWCKYNMAPEGSSKKIEAQKQLLELMSHRAHVDNSITLIGKLLFGVNKASKVLNTVRPVGQPLVDDWQCLKAMIRTFETHCGSLSEYGMKHTLSFANMCNAGIQKEQLAEAAAQACVTFPSNPYSSLAEGFSA 6iz2 A 2.07 BS01 ZN A 1 E52 H136 E49 H126 Q9RY97 30961930 KLLLSPAELLAHWQGHRDLTRRVIEAFPEEGFAAHHAPDMRPFQAMACELAGMVEYQLDWFRRGQPTWELPGRAELLAWWDKLTAELGAEVPQVSTEMWATPATTPFGKMSPLMSVMYLIDNEVHHRGQGYVYLRELGVTPPAFY 6iz2 A 2.07 BS02 ZN A 2 H15 H19 H12 H16 Q9RY97 30961930 KLLLSPAELLAHWQGHRDLTRRVIEAFPEEGFAAHHAPDMRPFQAMACELAGMVEYQLDWFRRGQPTWELPGRAELLAWWDKLTAELGAEVPQVSTEMWATPATTPFGKMSPLMSVMYLIDNEVHHRGQGYVYLRELGVTPPAFY 6j3h A 2.19 BS01 GSH A 1 N22 N24 K27 Y46 I49 L66 Y72 S74 L75 P76 D89 S90 Y150 R155 N30 N32 K35 Y54 I57 L74 Y80 S82 L83 P84 D97 S98 Y158 R163 M2QJS8 30928378 GLVPRGSHMIQQIHFYDIPRNRDEDDRTWNPNTSKTRLTLTYKRLPYKTIWVEYPDIERVCKEIGAEPSAFGLLKEGKPYYSLPVIHDPNTGTTISDSIRIARYLDKTYPDTPAVIPAELEAFHAVFEDAFWDTIFMPLFPFLVPAACPQLNPRSEAYFRETREGKFGSILGGKMENWAPTGPVRDDRWKALQAGFTKMAGWLSADGQERPFFMGEKLCYTDIVVGAWLISVKKVFGSDHPEWLQVEKWDGGRWSRLVQVVENF 6j3h B 2.19 BS01 GSH B 1 I10 N22 N24 K27 Y46 I49 Y72 Y73 S74 L75 P76 D89 S90 Y150 R155 I10 N22 N24 K27 Y46 I49 Y72 Y73 S74 L75 P76 D89 S90 Y150 R155 M2QJS8 30928378 MIQQIHFYDIPRNRDEDDRTWNPNTSKTRLTLTYKRLPYKTIWVEYPDIERVCKEIGAEPSAFGLLKEGKPYYSLPVIHDPNTGTTISDSIRIARYLDKTYPDTPAVIPAELEAFHAVFEDAFWDTIFMPLFPFLVPAACPQLNPRSEAYFRETREGKFGSILGGKMENWAPTGPVRDDRWKALQAGFTKMAGWLSADGQERPFFMGEKLCYTDIVVGAWLISVKKVFGSDHPEWLQVEKWDGGRWSRLVQVVENF 6j7k A 2.15 BS01 TRH A 1 N13 Y14 G15 D16 Y112 F190 Y192 P216 F251 M252 Q254 Y257 R270 G271 E272 D273 S274 N14 Y15 G16 D17 Y113 F191 Y193 P217 F252 M253 Q255 Y258 R271 G272 E273 D274 S275 Q9HZZ1 HMASWDIFCSVVDNYGDIGVTWRLARQLAAEHGQAVRLWVDEPQAFARICPRADPVAHVQCLDGVEVRAWGRPWAPVAAADVVIEAFACELPEAHRQAMRERKRPSLWLNLEYLSAEEWIGSCHALPSLQACGLSKYFFFPGFREPSGGLLREAGLLERRRRFQASVSAQDEFLASLGVRRKVGERLISLFAYENPALPGWLEQLRDARQPSLLLVPEGRVLADVADWLRVATLAVGDVHVRDALRVQVLPFMAQDDYDRLLWCCDLNAVRGEDSFVRAQWAGRPLLWHIYRQEEETHLAKLEAFLELYCAGLPADLAENLRTFWLAWNAGGGLAGAWEGLERQLPEWRREAQRWADEQGMRPDLAARLVQFYADWLLEHHHHHH 6j7l A 1.85 BS01 TYD A 1 N13 Y14 G15 F190 Y192 P216 F251 M252 Q254 Y257 R270 G271 E272 D273 S274 N16 Y17 G18 F193 Y195 P219 F254 M255 Q257 Y260 R273 G274 E275 D276 S277 Q9HZZ1 FQHMASWDIFCSVVDNYGDIGVTWRLARQLAAEHGQAVRLWVDEPQAFARICPRADPVAHVQCLDGVEVRAWGRPWAPVAAADVVIEAFACELPEAHRQAMRERKRPSLWLNLEYLSAEEWIGSCHALPSLQACGLSKYFFFPGFREPSGGLLREAGLLERRRRFQASVSAQDEFLASLGVRRKVGERLISLFAYENPALPGWLEQLRDARQPSLLLVPEGRVLADVADWLRVATLAVGDVHVRDALRVQVLPFMAQDDYDRLLWCCDLNAVRGEDSFVRAQWAGRPLLWHIYRTHLAKLEAFLELYCAGLPADLAENLRTFWLAWNAGGGLAGAWEGLERQLPEWRREAQRWADEQGMRPDLAARLVQFYADWLLEHHHHHH 6jav A 1.44 BS01 BC0 A 1 W1621 R1625 W1691 D1804 W1809 A1896 F1899 W16 R20 W86 D199 W204 A281 F284 3.2.1.14 A0A221ZS22 31053640 SLLNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDGLDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDYRNRCGQGKHPLLNAIKTELLNPKI 6jaw A 1.98 BS01 BBO A 1 W1691 D1804 W1809 Y1856 W1961 W86 D199 W204 Y251 W346 3.2.1.14 A0A221ZS22 31053640 SLLNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDGLDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDYRNRCGQGKHPLLNAIKTELLNPKI 6jax A 1.70 BS01 GCS A 1 V1740 F1830 V135 F225 3.2.1.14 A0A221ZS22 31053640 SLLNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDGLDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDYRNRCGQGKHPLLNAIKTELLNPKI 6jax A 1.70 BS02 GCS A 2 W1691 V1740 W1809 W86 V135 W204 3.2.1.14 A0A221ZS22 31053640 SLLNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDGLDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDYRNRCGQGKHPLLNAIKTELLNPKI 6jax A 1.70 BS03 GCS A 3 W1621 W1691 W16 W86 3.2.1.14 A0A221ZS22 31053640 SLLNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDGLDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDYRNRCGQGKHPLLNAIKTELLNPKI 6jax A 1.70 BS04 GCS A 4 W1621 H1660 N1692 W16 H55 N87 3.2.1.14 A0A221ZS22 31053640 SLLNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDGLDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDYRNRCGQGKHPLLNAIKTELLNPKI 6jax A 1.70 BS05 GCS A 5 Y1624 H1660 Y19 H55 3.2.1.14 A0A221ZS22 31053640 SLLNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDGLDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDYRNRCGQGKHPLLNAIKTELLNPKI 6jay A 1.50 BS01 JUK A 1 W1621 W1691 D1804 Q1808 W1809 W16 W86 D199 Q203 W204 3.2.1.14 A0A221ZS22 31053640 SLLNSRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNRFYERVVEYKRYGIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDGLDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKGLLLSAAVSPNKMVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDDTTYFNANYTIHYWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDRIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDYRNRCGQGKHPLLNAIKTELLNPKI 6jia A 1.90 BS02 ALL A 1 G51 W130 G30 W109 NWTLVWQDEFTNGISSDWVFETGNGNSGWGNNELQYYRRENATVENGNLVITAKRESIGGYNYTSTRMKTQGRKSWKYGKVEARIAMPSFMGSWPAFWMLGDNISSVGWPACGAIDIMEHVNTEAQTHGTIHWQDHNNTYANYSGSIPVSSVTSYHIYTIEWDASVIKWFVDGNLYHEASIANGVNGTSEFHNNFFILLNMAIGGNWPGFNIDNNAFPARMLVDYVRVYQK 6jia A 1.90 BS03 BGC A 1 G51 N52 R88 W130 G30 N31 R67 W109 NWTLVWQDEFTNGISSDWVFETGNGNSGWGNNELQYYRRENATVENGNLVITAKRESIGGYNYTSTRMKTQGRKSWKYGKVEARIAMPSFMGSWPAFWMLGDNISSVGWPACGAIDIMEHVNTEAQTHGTIHWQDHNNTYANYSGSIPVSSVTSYHIYTIEWDASVIKWFVDGNLYHEASIANGVNGTSEFHNNFFILLNMAIGGNWPGFNIDNNAFPARMLVDYVRVYQK 6jia A 1.90 BS04 GLC A 1 N52 W115 A117 W119 W130 D137 E140 H153 N31 W94 A96 W98 W109 D116 E119 H132 NWTLVWQDEFTNGISSDWVFETGNGNSGWGNNELQYYRRENATVENGNLVITAKRESIGGYNYTSTRMKTQGRKSWKYGKVEARIAMPSFMGSWPAFWMLGDNISSVGWPACGAIDIMEHVNTEAQTHGTIHWQDHNNTYANYSGSIPVSSVTSYHIYTIEWDASVIKWFVDGNLYHEASIANGVNGTSEFHNNFFILLNMAIGGNWPGFNIDNNAFPARMLVDYVRVYQK 6jkz A 1.40 BS01 CL A 1 W173 G389 T391 H392 W147 G363 T365 H366 A0A2S3SYP4 LSPEAITSAQVFSTQSKETYTYVRCWYRTGNSHDESATDWEWAENPDGSYFTIDGYWWSSKNMFYTNTSQNVIKQRCEETLGVTHDAADITYFAADNRWSYNHTIWTNDPVMQADQINKIVAFGDSLSDTGNIFNAAQWRFPNPDTWFLGHFSNGFVWTEYIAQAKKLPLYNWAVGGAAGSNQYVALTGVKDQVLSYLTYAKMAKNYKPENTLFTLEFGLNDFMNYNREVVDVKTDFSTALIKLTDAGAKNIMLMTLPDATKAPQFKYSTQAEIEKVRAKIVEFNEFIKAQAAFYIIQGYNITLYDTHGLFEQLTQNPQQHGFVNASDACLNINRASSADYLYSHSLTNECATHSSDKYVFWGVTHPTTAVHKYIAEKMLAPGAGMQRFNFHHHHH 6jkz A 1.40 BS02 1PS A 1 K87 T130 N158 N198 W199 V201 K61 T104 N132 N172 W173 V175 A0A2S3SYP4 LSPEAITSAQVFSTQSKETYTYVRCWYRTGNSHDESATDWEWAENPDGSYFTIDGYWWSSKNMFYTNTSQNVIKQRCEETLGVTHDAADITYFAADNRWSYNHTIWTNDPVMQADQINKIVAFGDSLSDTGNIFNAAQWRFPNPDTWFLGHFSNGFVWTEYIAQAKKLPLYNWAVGGAAGSNQYVALTGVKDQVLSYLTYAKMAKNYKPENTLFTLEFGLNDFMNYNREVVDVKTDFSTALIKLTDAGAKNIMLMTLPDATKAPQFKYSTQAEIEKVRAKIVEFNEFIKAQAAFYIIQGYNITLYDTHGLFEQLTQNPQQHGFVNASDACLNINRASSADYLYSHSLTNECATHSSDKYVFWGVTHPTTAVHKYIAEKMLAPGAGMQRFNFHHHHH 6jkz A 1.40 BS03 1PS A 2 Y45 W65 Y73 D122 R124 Y22 W42 Y50 D96 R98 A0A2S3SYP4 LSPEAITSAQVFSTQSKETYTYVRCWYRTGNSHDESATDWEWAENPDGSYFTIDGYWWSSKNMFYTNTSQNVIKQRCEETLGVTHDAADITYFAADNRWSYNHTIWTNDPVMQADQINKIVAFGDSLSDTGNIFNAAQWRFPNPDTWFLGHFSNGFVWTEYIAQAKKLPLYNWAVGGAAGSNQYVALTGVKDQVLSYLTYAKMAKNYKPENTLFTLEFGLNDFMNYNREVVDVKTDFSTALIKLTDAGAKNIMLMTLPDATKAPQFKYSTQAEIEKVRAKIVEFNEFIKAQAAFYIIQGYNITLYDTHGLFEQLTQNPQQHGFVNASDACLNINRASSADYLYSHSLTNECATHSSDKYVFWGVTHPTTAVHKYIAEKMLAPGAGMQRFNFHHHHH 6jl2 A 2.30 BS01 1PS A 1 K87 N158 N198 W199 V201 A212 L213 Y226 K65 N136 N176 W177 V179 A190 L191 Y204 A0A2S3SYP4 ALSPEAITSAQVFSTQSKETYTYVRCWYRTGNSHDESATDWEWAENPDGSYFTIDGYWWSSVRLKNMFYTNTSQNVIKQRCEETLGVTHDAADITYFAADNRWSYNHTIWTNDPVMQADQINKIVAFGDSLSDTGNIFNAAQWRFPNPDTWFLGHFSNGFVWTEYIAQAKKLPLYNWAVGGAAGSNQYVALTGVKDQVLSYLTYAKMAKNYKPENTLFTLEFGLNDFMNYNREVVDVKTDFSTALIKLTDAGAKNIMLMTLPDATKAPQFKYSTQAEIEKVRAKIVEFNEFIKAQAAFYIIQGYNITLYDTHGLFEQLTQNPQQHGFVNASDACLNINRASSADYLYSHSLTNECATHSSDKYVFWNVTHPTTAVHKYIAEKMLAPGAGMQRFNFHHHHHH 6jl2 A 2.30 BS02 1PS A 2 R124 W125 S126 Y127 Q164 W165 R102 W103 S104 Y105 Q142 W143 A0A2S3SYP4 ALSPEAITSAQVFSTQSKETYTYVRCWYRTGNSHDESATDWEWAENPDGSYFTIDGYWWSSVRLKNMFYTNTSQNVIKQRCEETLGVTHDAADITYFAADNRWSYNHTIWTNDPVMQADQINKIVAFGDSLSDTGNIFNAAQWRFPNPDTWFLGHFSNGFVWTEYIAQAKKLPLYNWAVGGAAGSNQYVALTGVKDQVLSYLTYAKMAKNYKPENTLFTLEFGLNDFMNYNREVVDVKTDFSTALIKLTDAGAKNIMLMTLPDATKAPQFKYSTQAEIEKVRAKIVEFNEFIKAQAAFYIIQGYNITLYDTHGLFEQLTQNPQQHGFVNASDACLNINRASSADYLYSHSLTNECATHSSDKYVFWNVTHPTTAVHKYIAEKMLAPGAGMQRFNFHHHHHH 6jl2 A 2.30 BS03 1PS A 3 W80 R85 N88 D122 S126 Y127 H129 W58 R63 N66 D100 S104 Y105 H107 A0A2S3SYP4 ALSPEAITSAQVFSTQSKETYTYVRCWYRTGNSHDESATDWEWAENPDGSYFTIDGYWWSSVRLKNMFYTNTSQNVIKQRCEETLGVTHDAADITYFAADNRWSYNHTIWTNDPVMQADQINKIVAFGDSLSDTGNIFNAAQWRFPNPDTWFLGHFSNGFVWTEYIAQAKKLPLYNWAVGGAAGSNQYVALTGVKDQVLSYLTYAKMAKNYKPENTLFTLEFGLNDFMNYNREVVDVKTDFSTALIKLTDAGAKNIMLMTLPDATKAPQFKYSTQAEIEKVRAKIVEFNEFIKAQAAFYIIQGYNITLYDTHGLFEQLTQNPQQHGFVNASDACLNINRASSADYLYSHSLTNECATHSSDKYVFWNVTHPTTAVHKYIAEKMLAPGAGMQRFNFHHHHHH 6jl2 B 2.30 BS01 1PS B 1 K87 N158 N198 W199 V201 Y226 K63 N134 N174 W175 V177 Y202 A0A2S3SYP4 SPEAITSAQVFSTQSKETYTYVRCWYRTGNSHDESATDWEWAENPDGSYFTIDGYWWSSVRLKNMFYTNTSQNVIKQRCEETLGVTHDAADITYFAADNRWSYNHTIWTNDPVMQADQINKIVAFGDSLSDTGNIFNAAQWRFPNPDTWFLGHFSNGFVWTEYIAQAKKLPLYNWAVGGAAGSNQYVALTGVKDQVLSYLTYAKMAKNYKPENTLFTLEFGLNDFMNYNREVVDVKTDFSTALIKLTDAGAKNIMLMTLPDATKAPQFKYSTQAEIEKVRAKIVEFNEFIKAQAAFYIIQGYNITLYDTHGLFEQLTQNPQQHGFVNASDACLNINSADYLYSHSLTNECATHSSDKYVFWNVTHPTTAVHKYIAEKMLAPGAGMQRFNFH 6jl2 C 2.30 BS01 1PS C 1 K87 M89 N158 N198 W199 V201 L213 S222 Y226 K59 M61 N130 N170 W171 V173 L185 S194 Y198 A0A2S3SYP4 SPEAITSAQVFSTQSKETYTYVRCWYRTGNSHDESATDWEWAENPDGSYFTIDGYWWLKNMFYTNTSQNVIKQRCEETLGVTHDAADITYFAADNRWSYNHTIWTNDPVMQADQINKIVAFGDSLSDTGNIFNAAQWRFPNPDTWFLGHFSNGFVWTEYIAQAKKLPLYNWAVGGAAGSNQYVALTGVKDQVLSYLTYAKMAKNYKPENTLFTLEFGLNDFMNYNREVVDVKTDFSTALIKLTDAGAKNIMLMTLPDATKAPQFKYSTQAEIEKVRAKIVEFNEFIKAQAAFYIIQGYNITLYDTHGLFEQLTQNPQQHGFVNASDACLNISADYLYSHSLTNECATHSSDKYVFWNVTHPTTAVHKYIAEKMLAPGAGMQRFNFH 6jm9 A 7.30 BS01 NUC I 1 R42 P43 R63 R72 R83 F84 Q85 S86 R116 V117 T118 R5 P6 R26 R35 R46 F47 Q48 S49 R79 V80 T81 P84233 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 6jm9 X 7.30 BS01 SAM X 1 P133 V135 Y136 G137 E138 T139 D161 G163 S164 E186 K187 A188 D222 F223 L224 S225 F239 N241 F245 P129 V131 Y132 G133 E134 T135 D157 G159 S160 E182 K183 A184 D218 F219 L220 S221 F235 N237 F241 2.1.1.43 Q8TEK3 LELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNP 6jma C 6.80 BS02 NUC J 1 R29 R35 R42 V43 G44 A45 R16 R22 R29 V30 G31 A32 Q6AZJ8 AKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPKKT 6jma X 6.80 BS01 SAM X 1 P133 E134 V135 Y136 G137 T139 G163 S164 V169 E186 K187 A188 D222 F223 L224 F239 N241 F245 P129 E130 V131 Y132 G133 T135 G159 S160 V165 E182 K183 A184 D218 F219 L220 F235 N237 F241 2.1.1.43 Q8TEK3 LELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNP 6jnk A 2.20 BS01 NAP A 1 G13 K14 I15 S37 R38 H39 C67 A68 P69 V72 R73 E90 K91 H119 H153 Q156 W158 D169 Y266 G10 K11 I12 S34 R35 H36 C64 A65 P66 V69 R70 E87 K88 H116 H150 Q153 W155 D166 Y263 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKEDVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFGR 6jpj A 2.64 BS01 FGF A 1 L473 V481 R483 T499 V500 A501 K503 V550 E551 C552 A553 A554 L619 L20 V28 R30 T46 V47 A48 K50 V97 E98 C99 A100 A101 L166 2.7.10.1 P22455 31041948 LPLDPLWEFPRDRLVLGKPLGEGAFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDEVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSE 6jx8 C 2.67 BS01 6NA C 1 H93 G95 N99 Q150 H88 G90 N94 Q145 Q9GK12 CGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 6jx8 D 2.67 BS01 6NA C 1 P96 Q150 P151 P91 Q145 P146 Q9GK12 CGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 6mav A 2.37 BS03 CA A 3 D141 G173 I174 N175 G176 D177 D55 G87 I88 N89 G90 D91 3.4.24.17 P08254 31040180 PGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYG 6mo1 A 3.00 BS01 I16 A 1 K1073 K1074 D1075 L1076 T1120 G1148 L1149 G1151 I1165 K80 K81 D82 L83 T127 G155 L156 G158 I159 Q91H74 31017399 MADLELERAADVRWEEQAEISGSSLEDGAYRIKQKGILGYSQIGAGVYKEGTFHTMWHVTRGAVLMHKGKRIEPSWADVKKDLISYGGGWKLEGEWKEGEEVQVLALEPGKNPRAVQTKPGLFKTNTGTIGAVSLDFSPGTSGSPIVDKKGKVVGLYGIANTEK 6mo1 B 3.00 BS01 I16 B 1 K1073 K1074 D1075 L1076 L1149 G1151 I1165 K80 K81 D82 L83 L156 G158 I159 Q91H74 31017399 MADLELERAADVRWEEQAEISGSSLEDGAYRIKQKGILGYSQIGAGVYKEGTFHTMWHVTRGAVLMHKGKRIEPSWADVKKDLISYGGGWKLEGEWKEGEEVQVLALEPGKNPRAVQTKPGLFKTNTGTIGAVSLDFSPGTSGSPIVDKKGKVVGLYGIANTEK 6mo2 B 2.80 BS01 JVM B 1 M1049 K1073 K1074 D1075 L1076 L1149 G1151 I1165 M56 K80 K81 D82 L83 L156 G158 I159 Q91H74 31017399 MADLELERAADVRWEEQAEISGSSLEDGAYRIKQKGILGYSQIGAGVYKEGTFHTMWHVTRGAVLMHKGKRIEPSWADVKKDLISYGGGWKLEGEWKEGEEVQVLALEPGKNPRAVQTKPGLFKTNTGTIGAVSLDFSPGTSGSPIVDKKGKVVGLYGIANTEK 6mr9 A 1.35 BS01 THG A 1 I5 A6 A7 M16 D27 L28 W30 F31 K32 T46 I50 L54 R57 I94 Y100 T113 I5 A6 A7 M16 D24 L25 W27 F28 K29 T43 I47 L51 R54 I91 Y97 T110 1.5.1.3 P0ABQ4 30868089 MISLIAALAVDRVIGMMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERRHHH 6mt8 A 1.35 BS01 THG A 1 I5 A6 A7 D27 L28 W30 F31 K32 T46 I50 R57 I94 Y100 T113 I5 A6 A7 D24 L25 W27 F28 K29 T43 I47 R54 I91 Y97 T110 1.5.1.3 P0ABQ4 30868089 MISLIAALAVDRVIGMMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERRHHH 6n6o A 2.60 BS01 KE7 A 1 I531 V539 Q541 A551 M602 E603 C604 G605 N606 I607 D608 S611 L654 I17 V25 Q27 A37 M88 E89 C90 G91 N92 I93 D94 S97 L140 2.7.12.1 P33981 30998356 NECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANTVNYMPPEAIKDMSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 6n9d A 2.67 BS05 CA A 3 A140 D141 G171 G173 N175 D177 A54 D55 G85 G87 N89 D91 3.4.24.17 P08254 31040180 PGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYG 6nor A 2.40 BS01 NAD A 1 V10 G11 G13 F14 M15 D36 R37 A72 T73 P74 H78 E95 K96 G122 N124 T161 W163 Y293 V18 G19 G21 F22 M23 D44 R45 A80 T81 P82 H86 E103 K104 G130 N132 T169 W171 Y301 Q70KD1 30995396 GLVPRGSHMVERLGVAVVGGGFMGGVHAEVLTADPRVDLRWVVDRDERVGTDLATRFGARVTTTLDEALADDTVRFVVVATPAATHEPIAAQVIAAGRNVLVEKPLVLSTGHARQLAAAAHERGVVLAHGGNFVYAPKFVRAHELAADREALGTVHSVRVAFRTSGPDTDWFRSKATAGGGALTDLGWHAVELCRWMLGKPAIRAVTACTRQLSAAGDVEDQGVVLIEFADGAIGQCDVSWACPGGEQLTVEVIGTEGLVTADLWQGMGVEAYTNTKFGAVWEPNQGWLRPEWEWIRNSGYVHQDRQVVDAVLDGRPMTHTPDDAVAVVETLEAAYRSAADGRKVEMNA 6nor B 2.40 BS01 NAD B 1 V10 G11 G13 F14 M15 V35 D36 R37 A72 T73 P74 H78 E95 K96 G122 N124 T161 W163 F164 Y293 V11 G12 G14 F15 M16 V36 D37 R38 A73 T74 P75 H79 E96 K97 G123 N125 T162 W164 F165 Y294 Q70KD1 30995396 HMVERLGVAVVGGGFMGGVHAEVLTADPRVDLRWVVDRDERVGTDLATRFGARVTTTLDEALADDTVRFVVVATPAATHEPIAAQVIAAGRNVLVEKPLVLSTGHARQLAAAAHERGVVLAHGGNFVYAPKFVRAHELAADREALGTVHSVRVAFRTSGPDTDWFRSKATAGGGALTDLGWHAVELCRWMLGKPAIRAVTACTRQLSAAGDVEDQGVVLIEFADGAIGQCDVSWACPGGEQLTVEVIGTEGLVTADLWQGMGVEAYTNTKFGAVWEPNQGWLRPEWEWIRNSGYVHQDRQVVDAVLDGRPMTHTPDDAVAVVETLEAAYRSAADGRKVEMN 6nor C 2.40 BS01 NAD C 1 G11 G13 F14 M15 D36 R37 A72 T73 P74 H78 E95 K96 G122 N124 W163 F164 H181 Y293 G10 G12 F13 M14 D35 R36 A71 T72 P73 H77 E94 K95 G121 N123 W162 F163 H180 Y292 Q70KD1 30995396 VERLGVAVVGGGFMGGVHAEVLTADPRVDLRWVVDRDERVGTDLATRFGARVTTTLDEALADDTVRFVVVATPAATHEPIAAQVIAAGRNVLVEKPLVLSTGHARQLAAAAHERGVVLAHGGNFVYAPKFVRAHELAADREALGTVHSVRVAFRTSGPDTDWFRSKATAGGGALTDLGWHAVELCRWMLGKPAIRAVTACTRQLSAAGDVEDQGVVLIEFADGAIGQCDVSWACPGGEQLTVEVIGTEGLVTADLWQGMGVEAYTNTKFGAVWEPNQGWLRPEWEWIRNSGYVHQDRQVVDAVLDGRPMTHTPDDAVAVVETLEAAYRSAADGRKVEMNA 6nor D 2.40 BS01 NAD D 1 V10 G11 G13 F14 M15 D36 R37 A72 T73 P74 H78 I81 E95 K96 N124 W163 H181 Y293 V11 G12 G14 F15 M16 D37 R38 A73 T74 P75 H79 I82 E96 K97 N125 W164 H182 Y294 Q70KD1 30995396 HMVERLGVAVVGGGFMGGVHAEVLTADPRVDLRWVVDRDERVGTDLATRFGARVTTTLDEALADDTVRFVVVATPAATHEPIAAQVIAAGRNVLVEKPLVLSTGHARQLAAAAHERGVVLAHGGNFVYAPKFVRAHELAADREALGTVHSVRVAFRTSGPDTDWFRSKATAGGGALTDLGWHAVELCRWMLGKPAIRAVTACTRQLSAAGDVEDQGVVLIEFADGAIGQCDVSWACPGGEQLTVEVIGTEGLVTADLWQGMGVEAYTNTKFGAVWEPNQGWLRPEWEWIRNSGYVHQDRQVVDAVLDGRPMTHTPDDAVAVVETLEAAYRSAADGRKVEMN 6nor E 2.40 BS01 NAD E 1 G11 G13 F14 M15 D36 R37 A72 T73 P74 H78 E95 K96 N124 W163 F164 Y293 G9 G11 F12 M13 D34 R35 A70 T71 P72 H76 E93 K94 N122 W161 F162 Y291 Q70KD1 30995396 ERLGVAVVGGGFMGGVHAEVLTADPRVDLRWVVDRDERVGTDLATRFGARVTTTLDEALADDTVRFVVVATPAATHEPIAAQVIAAGRNVLVEKPLVLSTGHARQLAAAAHERGVVLAHGGNFVYAPKFVRAHELAADREALGTVHSVRVAFRTSGPDTDWFRSKATAGGGALTDLGWHAVELCRWMLGKPAIRAVTACTRQLSAAGDVEDQGVVLIEFADGAIGQCDVSWACPGGEQLTVEVIGTEGLVTADLWQGMGVEAYTNTKFGAVWEPNQGWLRPEWEWIRNSGYVHQDRQVVDAVLDGRPMTHTPDDAVAVVETLEAAYRSAADGRKVEMN 6nor F 2.40 BS01 NAD F 1 V10 G11 G13 F14 M15 D36 R37 D38 V41 A72 T73 P74 H78 E95 K96 N124 T161 W163 F164 Y293 V9 G10 G12 F13 M14 D35 R36 D37 V40 A71 T72 P73 H77 E94 K95 N123 T160 W162 F163 Y292 Q70KD1 30995396 VERLGVAVVGGGFMGGVHAEVLTADPRVDLRWVVDRDERVGTDLATRFGARVTTTLDEALADDTVRFVVVATPAATHEPIAAQVIAAGRNVLVEKPLVLSTGHARQLAAAAHERGVVLAHGGNFVYAPKFVRAHELAADREALGTVHSVRVAFRTSGPDTDWFRSKATAGGGALTDLGWHAVELCRWMLGKPAIRAVTACTRQLSAAGDVEDQGVVLIEFADGAIGQCDVSWACPGGEQLTVEVIGTEGLVTADLWQGMGVEAYTNTKFGAVWEPNQGWLRPEWEWIRNSGYVHQDRQVVDAVLDGRPMTHTPDDAVAVVETLEAAYRSAADGRKVEMNA 6o6f A 1.60 BS01 LOD A 1 A227 F228 V249 M250 V253 R263 T266 L267 F270 L290 A57 F58 V79 M80 V83 R93 T96 L97 F100 L120 Q07820 30254093 SDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV 6o6f B 1.60 BS01 LOD B 1 F228 M231 V249 M250 V253 R263 T266 L267 F270 G271 L290 F57 M60 V78 M79 V82 R92 T95 L96 F99 G100 L119 Q07820 30254093 SDELYRQSLEIISRYLREQATGAKDTKPMGSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV 6o6g A 2.40 BS01 LOJ A 1 F228 M231 L246 M250 V253 R263 L267 F270 G271 V274 L290 F52 M55 L70 M74 V77 R87 L91 F94 G95 V98 L114 Q07820 30254093 DELYRQSLEIISRYLREQATGAKDRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV 6o81 C 3.21 BS01 C7B C 1 N162 V164 H188 I190 T215 V225 N128 V130 H154 I156 T181 V191 P49770 31048491 GSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL 6o81 E 3.21 BS01 C7B C 1 V177 S178 L179 L485 V12 S13 L14 L320 Q9UI10 31048491 QVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSD 6o85 C 3.03 BS01 C7B C 1 V164 H188 I190 T215 V130 H154 I156 T181 P49770 31048491 GSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL 6oe3 A 2.90 BS01 M9A A 1 L100 K101 K102 K103 V106 V108 V179 Y181 Y188 G190 F227 W229 L234 P236 Y318 L94 K95 K96 K97 V100 V102 V173 Y175 Y182 G184 F221 W223 L228 P230 Y312 2.7.7.49,2.7.7.7,3.1.26.13 P03366 31034849 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLV 6oi4 A 1.76 BS01 III E 1 M31 T36 T37 V38 T39 P40 K42 K44 R64 V85 Q87 C88 R92 K97 R104 W108 Q110 P112 M12 T17 T18 V19 T20 P21 K23 K25 R45 V66 Q68 C69 R72 K77 R84 W88 Q90 P92 Q16186 NKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNP 6oi4 B 1.76 BS01 III F 1 M31 T36 T37 V38 P40 K42 K44 R64 V85 Q87 C88 G91 R92 V93 K97 R104 W108 Q110 P112 M11 T16 T17 V18 P20 K22 K24 R44 V65 Q67 C68 G70 R71 V72 K76 R81 W85 Q87 P89 Q16186 KYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCSGRVYVLKFKSKRLFFWMQEPKTDQDEEHCRKVNEYLNNP 6oiw A 3.35 BS01 MG A 1 K211 D268 D269 K210 D267 D268 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ 6oiw B 3.35 BS02 T8T B 1 V54 D118 H126 K232 D268 Y272 D276 F391 V396 E400 V53 D117 H125 K231 D267 Y271 D275 F390 V395 E399 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oiw C 3.35 BS02 T8T C 1 Q53 V54 H126 K211 Y212 K232 D268 D269 Y272 D276 F391 V396 E400 Q52 V53 H125 K210 Y211 K231 D267 D268 Y271 D275 F390 V395 E399 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oiw D 3.35 BS02 T8T D 1 V54 D118 H126 K211 Y212 K232 Y272 D276 F391 V396 E400 V53 D117 H125 K210 Y211 K231 Y271 D275 F390 V395 E399 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ 6oiw D 3.35 BS03 T8T E 1 R433 R442 R432 R441 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ 6oiw E 3.35 BS01 MG E 1 D268 D269 Y272 D267 D268 Y271 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oiw E 3.35 BS03 T8T E 1 Q53 V54 H117 H126 N186 K211 Y212 K232 Y272 D276 F391 V396 E400 Q52 V53 H116 H125 N185 K210 Y211 K231 Y271 D275 F390 V395 E399 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oiw F 3.35 BS01 MG F 1 D268 D269 D267 D268 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oiw F 3.35 BS02 MN F 1 H69 H117 D118 D268 Y272 H68 H116 D117 D267 Y271 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oiw F 3.35 BS03 T8T F 1 Q53 V54 H126 N186 K211 K232 Y272 D276 F391 V396 E400 Q52 V53 H125 N185 K210 K231 Y271 D275 F390 V395 E399 3.1.5.1 P15723 31019074 AQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oiy D 3.29 BS02 DGT D 1 Q53 V54 H126 E184 N186 K211 Y212 K232 D268 Y272 D276 F391 V396 E400 Q51 V52 H124 E182 N184 K209 Y210 K230 D266 Y270 D274 F379 V384 E388 3.1.5.1 P15723 31019074 QIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGSLFSLVVENAWEKSRSSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oiy E 3.29 BS01 DGT E 1 Q53 V54 N186 Y212 K232 D268 Y272 D276 F391 V396 E400 Q51 V52 N184 Y210 K230 D266 Y270 D274 F379 V384 E388 3.1.5.1 P15723 31019074 QIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGSLFSLVVENAWEKSRSSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVE 6oqb A 1.60 BS01 N0J A 1 H224 A227 F228 M231 L235 V249 M250 V253 F254 R263 T266 L267 F270 G271 L290 I294 H53 A56 F57 M60 L64 V78 M79 V82 F83 R92 T95 L96 F99 G100 L119 I123 Q07820 30254093 DELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEG 6oqc A 1.80 BS01 N0S A 1 H224 A227 F228 V249 M250 V253 R263 T266 L267 F270 G271 L290 I294 H54 A57 F58 V79 M80 V83 R93 T96 L97 F100 G101 L120 I124 Q07820 30254093 EDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVE 6oqn B 1.70 BS01 N0P B 1 A227 V249 M250 V253 F254 R263 T266 L267 F270 L290 A57 V79 M80 V83 F84 R93 T96 L97 F100 L120 Q07820 30254093 EDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV 6oqq A 2.10 BS01 AMP A 1 H492 R500 D502 R505 Y506 Q507 V510 Q517 F518 Q519 G521 N733 R734 H394 R402 D404 R407 Y408 Q409 V412 Q419 F420 Q421 G423 N635 R636 Q5ZTK6 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 6oqq A 2.10 BS02 POP A 1 R352 K367 K370 R536 D542 R254 K269 K272 R438 D444 Q5ZTK6 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 6oqq A 2.10 BS03 MG A 1 D542 D545 D444 D447 Q5ZTK6 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 6oqq A 2.10 BS04 MG A 2 Y443 Y449 R536 Y345 Y351 R438 Q5ZTK6 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 6oqq A 2.10 BS05 MG A 3 Q350 Y452 Y532 R536 Q252 Y354 Y434 R438 Q5ZTK6 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 6oqq A 2.10 BS06 MG A 4 T493 F495 Y732 T395 F397 Y634 Q5ZTK6 VKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQRFWR 6oqq B 2.10 BS01 CA B 1 D21 D23 N25 S27 D18 D20 N22 S24 P06787 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMINIQQFAALLS 6oqq B 2.10 BS02 CA B 2 D94 N96 D98 L100 D91 N93 D95 L97 P06787 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMINIQQFAALLS 6oqq C 2.10 BS01 AMP C 1 H492 R500 D502 R505 Y506 Q507 V510 Q517 F518 Q519 G521 H393 R401 D403 R406 Y407 Q408 V411 Q418 F419 Q420 G422 Q5ZTK6 KQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQ 6oqq C 2.10 BS02 POP C 1 R352 K367 R536 D542 R253 K268 R437 D443 Q5ZTK6 KQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQ 6oqq C 2.10 BS03 POP C 2 T493 R500 Y732 N733 T394 R401 Y633 N634 Q5ZTK6 KQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQ 6oqq C 2.10 BS05 MG C 2 Y443 R536 Y344 R437 Q5ZTK6 KQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATRNELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVWKMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAHSYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQGRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISRGSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADIFHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTKHYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPKKEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYSIYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVEKILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAITIQ 6ote A 2.95 BS01 SSA A 1 T250 E252 R281 E283 F295 R296 I297 F300 E304 E368 L369 V370 S371 N404 G405 T406 A409 R412 T222 E224 R253 E255 F267 R268 I269 F272 E276 E340 L341 V342 S343 N367 G368 T369 A372 R375 Q5CVB3 IDINRIRVEKGGDYQKIAESEMARYKGLETLEELVKVDQKWREDMFKLEQSKKESVQLKKNLPIIEKQALETEEVRDKLWHKIGNVLQPDVPISNTEDDNLVLRTWGEIPDIKVDGTPGKLHHNEIMSRLGFYDSVKGAELAGHRGYFLKDYGVIMSMALSHYAMGFLLKKGYLAIQPPYFMKRDLMGKAAELQDFEETLYHIPSDNSKGEVDSNSLFLIATSEQPIAAMHHNVTLEDKDLPIKYAGISTCFRKEAGAHGKDTWGIFRIHQFEKVEQFCVTLPEDSQKIHEEMISISEEFYQSLELPYRVISIVSGALNDAASKKYDLEAWFPGYNSYRELVSCSNCTDYQSRALECRLKHYCHFLNGTLCAIQRTMCCIVENYQTPDGLRIPKVLQPYMNGVEFIPFK 6ote A 2.95 BS02 MG A 1 K353 E368 S371 K325 E340 S343 Q5CVB3 IDINRIRVEKGGDYQKIAESEMARYKGLETLEELVKVDQKWREDMFKLEQSKKESVQLKKNLPIIEKQALETEEVRDKLWHKIGNVLQPDVPISNTEDDNLVLRTWGEIPDIKVDGTPGKLHHNEIMSRLGFYDSVKGAELAGHRGYFLKDYGVIMSMALSHYAMGFLLKKGYLAIQPPYFMKRDLMGKAAELQDFEETLYHIPSDNSKGEVDSNSLFLIATSEQPIAAMHHNVTLEDKDLPIKYAGISTCFRKEAGAHGKDTWGIFRIHQFEKVEQFCVTLPEDSQKIHEEMISISEEFYQSLELPYRVISIVSGALNDAASKKYDLEAWFPGYNSYRELVSCSNCTDYQSRALECRLKHYCHFLNGTLCAIQRTMCCIVENYQTPDGLRIPKVLQPYMNGVEFIPFK 6otj A 2.85 BS01 TYR A 1 Y34 G36 D38 L68 T73 D78 Y171 Q175 D178 E191 Q197 Y34 G36 D38 L68 T73 D78 Y171 Q175 D178 E191 Q197 6.1.1.1 B4RP13 MSVIQDLQSRGLIAQTTDIEALDALLNEQKIALYCGFDPTADSLHIGHLLPVLALRRFQQAGHTPIALVGGATGMIGDPSFKAAERSLNSAETVAGWVGSIRSQLTPFLSFEGGNAAIMANNADWFGSMNCLDFLRDIGKHFSVNAMLNKESVKQRIDRDGAGISFTEFAYSLLQGYDFAELNKRHGAVLEIGGSDQWGNITAGIDLTRRLNQKQVFGLTLPLVTKSDGTKFGKTEGGAVWLNAKKTSPYQFYQFWLKVADADVYKFLKYFTFLSIEEIGVVEAKDKASGSKPEAQRILAEEMTRLIHGEEALAAAQRISESLFAEDQSRLTESDFEQLALDGLPAFEVSDGINAVEALVKTGLAASNKEARGFVNAKAVLLNGKPAEANNPNHPDDAYLLIGEYKRFGKYTILRRGKRNHALLVWK 6otu A 2.25 BS01 G6Q A 1 I149 G150 G151 S152 S202 K203 S204 T207 G260 R261 Q343 E347 Q486 K493 I146 G147 G148 S149 S199 K200 S201 T204 G257 R258 Q340 E344 Q483 K490 5.3.1.9 A0A0E9E8R5 KGFLDCESLVALQEMALHPIDLTASGCLSEERIQKNSLSVEGFTYSYATERVDDRCLEALQGLTEERELIKQMECMQQGAIMNRIEGFQSESRPVLHTATRAWVRDQDLHEEAAAIARHSKEEALRLAEFLYIARAKFSTLVQIGIGGSELGPKAMYFAMQGSCPSDKRIFFVSNIDPDNAAEVLREIDLEQTLVVVVSKSGTTLEPAANEELFRQAYQNKGLSIAEHFVAVTSQGSPMDDKSRYLEVFHLWDSIGGRFSATSMVGGVVLGFAFGYEAFIEFLQGAAAIDAHALTPKMRENLPLLSAMLGVWNRNLLGYPTTAVIPYSTGLKYFTAHLQQCGMESNGKSISREGKEISFRTSPIIWGDVGTNCQHSFFQSLHQGTDIVPVEFIGFLHNQRGLDCVLSGSSSSQKLFANLVAQSLALAQGRDNANPNKRFKGNSPSSILVAQQLSPRIAGSLLAFYEHKFAFQGFCWGINSFDQEGVSLGKELATQIIGIMSEFPEARGVLRLFNVLT 6ov8 A 2.61 BS02 MN A 1 D200 K207 D277 E279 D202 K209 D279 E281 3.4.11.23 P37095 NAMTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVVWPDLDDAQRQELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPEMIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLASAAQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGWLHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA 6q9h A 2.00 BS01 HRH A 1 L54 G58 I61 M62 F86 H96 I99 Y100 L36 G40 I43 M44 F68 H78 I81 Y82 2.3.2.27 Q00987 31066983 IPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVV 6q9o A 1.21 BS01 HU8 A 1 L54 F55 G58 I61 M62 Y67 F91 V93 K94 H96 I99 L38 F39 G42 I45 M46 Y51 F75 V77 K78 H80 I83 2.3.2.27 Q00987 31066983 SQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVV 6q9q A 2.10 BS01 HUE A 1 M54 L57 G58 I61 M62 Y67 Q72 V93 P96 L99 Y100 M29 L32 G33 I36 M37 Y42 Q47 V68 P71 L74 Y75 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9q A 2.10 BS02 O4B A 1 L32 K36 L81 L7 K11 L56 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9q B 2.10 BS02 O4B B 1 L32 P33 K36 L7 P8 K11 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9q B 2.10 BS03 O4B B 2 H39 G42 Q44 H14 G17 Q19 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9q C 2.10 BS01 HUE C 1 M54 G58 I61 M62 Y67 Q72 V93 P96 L99 Y100 M29 G33 I36 M37 Y42 Q47 V68 P71 L74 Y75 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLV 6q9q C 2.10 BS02 O4B C 1 K36 L81 K11 L56 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLV 6q9q D 2.10 BS02 O4B D 1 L32 P33 K36 L81 L7 P8 K11 L56 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9s A 2.40 BS01 HRN A 1 K51 M54 H55 L57 G58 I61 M62 Y67 Q72 V93 L99 K29 M32 H33 L35 G36 I39 M40 Y45 Q50 V71 L77 O15151 31066983 GQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9s A 2.40 BS02 O4B A 1 Q27 V28 V50 Y100 L103 R104 L107 T109 Q5 V6 V28 Y78 L81 R82 L85 T87 O15151 31066983 GQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9s A 2.40 BS03 O4B A 2 H55 Q59 M62 H33 Q37 M40 O15151 31066983 GQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9s A 2.40 BS04 O4B A 3 Q65 L66 Y76 Q43 L44 Y54 O15151 31066983 GQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9s C 2.40 BS03 O4B C 2 V28 V50 Y100 L103 T109 V6 V28 Y78 L81 T87 O15151 31066983 GQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTL 6q9s C 2.40 BS04 O4B C 3 G78 G83 G87 Q89 G56 G61 G65 Q67 O15151 31066983 GQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTL 6q9s C 2.40 BS05 O4B C 4 K31 P33 K105 N106 K9 P11 K83 N84 O15151 31066983 GQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTL 6q9s C 2.40 BS07 O4B C 6 L85 G87 K105 L63 G65 K83 O15151 31066983 GQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTL 6q9s B 2.40 BS01 HRN B 1 M54 H55 L57 G58 I61 M62 Y67 Q72 F91 V93 P96 L99 Y100 M29 H30 L32 G33 I36 M37 Y42 Q47 F66 V68 P71 L74 Y75 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLA 6q9s B 2.40 BS03 O4B B 2 H55 G58 Q59 M62 H30 G33 Q34 M37 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLA 6q9u A 2.40 BS02 O4B A 1 A40 V63 K64 L81 A16 V39 K40 L57 O15151 31066983 INQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTL 6q9w A 1.55 BS01 HRT A 1 M54 L57 G58 I61 M62 Y67 Q69 Q72 H73 M74 V75 F91 V93 P96 L99 Y100 M29 L32 G33 I36 M37 Y42 Q44 Q47 H48 M49 V50 F66 V68 P71 L74 Y75 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLA 6q9w A 1.55 BS03 O4B A 2 V93 K94 V68 K69 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLA 6q9w B 1.55 BS01 HRT B 1 M54 G58 I61 M62 Y67 Q69 Q72 L99 M29 G33 I36 M37 Y42 Q44 Q47 L74 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9w B 1.55 BS02 O4B B 1 L32 K36 L7 K11 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9w B 1.55 BS03 O4B B 2 Q72 H73 V93 K94 Q47 H48 V68 K69 O15151 31066983 NQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT 6q9y A 1.20 BS01 HRQ A 1 L57 G58 I61 Y67 Q72 V75 F91 V93 P96 L99 Y100 L103 L31 G32 I35 Y41 Q46 V49 F65 V67 P70 L73 Y74 L77 O15151 31066983 QVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLA 6qi9 B 4.63 BS01 ADP B 1 S17 H18 H20 G38 G73 T74 G75 K76 T77 A78 Y366 I374 R404 S16 H17 H19 G37 G72 T73 G74 K75 T76 A77 Y224 I232 R262 3.6.4.12 Q9Y265 31049401 KIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLTLHDLDVANAKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQD 6qi9 C 4.63 BS01 ADP C 1 H18 H20 V40 G73 T74 G75 K76 T77 Y366 L403 R404 H17 H19 V39 G72 T73 G74 K75 T76 Y230 L267 R268 3.6.4.12 Q9Y265 31049401 KIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLIIQDVTLHDLDVANADKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQD 6qi9 E 4.63 BS01 ADP E 1 H25 H27 G45 M46 V47 G48 G80 T81 G82 K83 T84 A85 Y362 I370 L399 H18 H20 G38 M39 V40 G41 G73 T74 G75 K76 T77 A78 Y244 I252 L281 3.6.4.12 Q9Y230 31049401 TKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRISLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFN 6qi9 F 4.63 BS01 ADP F 1 H25 G45 M46 V47 Q78 P79 G80 T81 G82 K83 T84 Y362 I370 L399 I403 H18 G38 M39 V40 Q71 P72 G73 T74 G75 K76 T77 Y242 I250 L279 I283 3.6.4.12 Q9Y230 31049401 TKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSITVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFN 6qkg A 2.20 BS01 SF4 A 1 R344 I347 C367 T368 A369 C370 N371 G373 C374 C386 M387 V388 R332 I335 C355 T356 A357 C358 N359 G361 C362 C374 M375 V376 E1YD54 31061390 MYENLCKPIKIGNHLVKNRMKYAATVDNFCDTKNGNVIDREIEYLRERAKGGFGIVVSQGGYTHILGKGYVGQMGLVEESHLPGLKKLADAINAEGAMSIGQIMHTGRYGHAHEYGIHEAIAGGKTVGPEPVGPTAMSSPIKRYSPCREMTPEEIEEQIQAHIVAARMFKQTGWKGVEVCAIVGYLIADFLSRWTNKRTDKWGGSLENRARFLIEILKGIRKEVGDDYPLVMRLNSTDLIEGGNTDEEYIEIAKMCEAAVRIDLFSITVGWHESPGAAITAEKRPGDWLHLADNWKKAGIKAPICMAYRMNQPDVAEKAVAEGRIDIWEMCRPGIADPYLPKKVCEGRPEDIVTCTACNQGCFYYVFIDAIMGCMVNPRVGNEWDPAYAINPAAKKKKVLVVGAGPSGMECARLAAVRGHDVTIMEKSDSIGGEVKLGVKSPLLYDWAETIRYYKAQIDKLGIKLKLNTEATADSIKAEAPDVLVIATGGKPSRPKIEGIDNKIVTNVFDILEGKVKLGDKVVFIGGNEISIQTAEYVAEQGKEVTVLEKGKHICFDVNIFNILQHRRLMAKLNMKSMTNVTINEINDDGVEISTAGGKDVTIEADNVVVAEGMDADDALAKAVGTKIAPEVYSIGDCAGVRKLYEAIHDGYKMGVKIRGS 6qkg A 2.20 BS02 FAD A 1 V414 G415 G417 P418 S419 M437 E438 K439 G445 E446 G450 W459 T481 E482 A483 A499 T500 G501 L524 E541 I542 Q545 G648 D649 K655 L656 A659 V402 G403 G405 P406 S407 M425 E426 K427 G433 E434 G438 W447 T469 E470 A471 A487 T488 G489 L512 E529 I530 Q533 G636 D637 K643 L644 A647 E1YD54 31061390 MYENLCKPIKIGNHLVKNRMKYAATVDNFCDTKNGNVIDREIEYLRERAKGGFGIVVSQGGYTHILGKGYVGQMGLVEESHLPGLKKLADAINAEGAMSIGQIMHTGRYGHAHEYGIHEAIAGGKTVGPEPVGPTAMSSPIKRYSPCREMTPEEIEEQIQAHIVAARMFKQTGWKGVEVCAIVGYLIADFLSRWTNKRTDKWGGSLENRARFLIEILKGIRKEVGDDYPLVMRLNSTDLIEGGNTDEEYIEIAKMCEAAVRIDLFSITVGWHESPGAAITAEKRPGDWLHLADNWKKAGIKAPICMAYRMNQPDVAEKAVAEGRIDIWEMCRPGIADPYLPKKVCEGRPEDIVTCTACNQGCFYYVFIDAIMGCMVNPRVGNEWDPAYAINPAAKKKKVLVVGAGPSGMECARLAAVRGHDVTIMEKSDSIGGEVKLGVKSPLLYDWAETIRYYKAQIDKLGIKLKLNTEATADSIKAEAPDVLVIATGGKPSRPKIEGIDNKIVTNVFDILEGKVKLGDKVVFIGGNEISIQTAEYVAEQGKEVTVLEKGKHICFDVNIFNILQHRRLMAKLNMKSMTNVTINEINDDGVEISTAGGKDVTIEADNVVVAEGMDADDALAKAVGTKIAPEVYSIGDCAGVRKLYEAIHDGYKMGVKIRGS 6qkg A 2.20 BS03 FMN A 1 A35 A36 T37 V38 G72 Q114 M116 C192 I194 R245 A319 Y320 R321 M342 C343 R344 P345 C374 F375 V378 M384 A23 A24 T25 V26 G60 Q102 M104 C180 I182 R233 A307 Y308 R309 M330 C331 R332 P333 C362 F363 V366 M372 E1YD54 31061390 MYENLCKPIKIGNHLVKNRMKYAATVDNFCDTKNGNVIDREIEYLRERAKGGFGIVVSQGGYTHILGKGYVGQMGLVEESHLPGLKKLADAINAEGAMSIGQIMHTGRYGHAHEYGIHEAIAGGKTVGPEPVGPTAMSSPIKRYSPCREMTPEEIEEQIQAHIVAARMFKQTGWKGVEVCAIVGYLIADFLSRWTNKRTDKWGGSLENRARFLIEILKGIRKEVGDDYPLVMRLNSTDLIEGGNTDEEYIEIAKMCEAAVRIDLFSITVGWHESPGAAITAEKRPGDWLHLADNWKKAGIKAPICMAYRMNQPDVAEKAVAEGRIDIWEMCRPGIADPYLPKKVCEGRPEDIVTCTACNQGCFYYVFIDAIMGCMVNPRVGNEWDPAYAINPAAKKKKVLVVGAGPSGMECARLAAVRGHDVTIMEKSDSIGGEVKLGVKSPLLYDWAETIRYYKAQIDKLGIKLKLNTEATADSIKAEAPDVLVIATGGKPSRPKIEGIDNKIVTNVFDILEGKVKLGDKVVFIGGNEISIQTAEYVAEQGKEVTVLEKGKHICFDVNIFNILQHRRLMAKLNMKSMTNVTINEINDDGVEISTAGGKDVTIEADNVVVAEGMDADDALAKAVGTKIAPEVYSIGDCAGVRKLYEAIHDGYKMGVKIRGS 6qkr A 2.20 BS04 J5H A 1 V38 Y82 I153 K154 R155 I194 V195 Y197 V281 G282 H284 E285 S286 P287 A290 I291 Y320 F375 F379 I572 F573 I575 L576 R579 V26 Y70 I141 K142 R143 I182 V183 Y185 V269 G270 H272 E273 S274 P275 A278 I279 Y308 F363 F367 I560 F561 I563 L564 R567 E1YD54 31061390 MYENLCKPIKIGNHLVKNRMKYAATVDNFCDTKNGNVIDREIEYLRERAKGGFGIVVSQGGYTHILGKGYVGQMGLVEESHLPGLKKLADAINAEGAMSIGQIMHTGRYGHAHEYGIHEAIAGGKTVGPEPVGPTAMSSPIKRYSPCREMTPEEIEEQIQAHIVAARMFKQTGWKGVEVCAIVGYLIADFLSRWTNKRTDKWGGSLENRARFLIEILKGIRKEVGDDYPLVMRLNSTDLIEGGNTDEEYIEIAKMCEAAVRIDLFSITVGWHESPGAAITAEKRPGDWLHLADNWKKAGIKAPICMAYRMNQPDVAEKAVAEGRIDIWEMCRPGIADPYLPKKVCEGRPEDIVTCTACNQGCFYYVFIDAIMGCMVNPRVGNEWDPAYAINPAAKKKKVLVVGAGPSGMECARLAAVRGHDVTIMEKSDSIGGEVKLGVKSPLLYDWAETIRYYKAQIDKLGIKLKLNTEATADSIKAEAPDVLVIATGGKPSRPKIEGIDNKIVTNVFDILEGKVKLGDKVVFIGGNEISIQTAEYVAEQGKEVTVLEKGKHICFDVNIFNILQHRRLMAKLNMKSMTNVTINEINDDGVEISTAGGKDVTIEADNVVVAEGMDADDALAKAVGTKIAPEVYSIGDCAGVRKLYEAIHDGYKMGVKIRG 6qkr B 2.20 BS04 J5H B 1 V38 Y82 I153 K154 R155 I194 V195 Y197 V281 G282 W283 H284 S286 P287 A290 Y320 F375 F379 I572 F573 L576 R579 V26 Y70 I141 K142 R143 I182 V183 Y185 V269 G270 W271 H272 S274 P275 A278 Y308 F363 F367 I560 F561 L564 R567 E1YD54 31061390 MYENLCKPIKIGNHLVKNRMKYAATVDNFCDTKNGNVIDREIEYLRERAKGGFGIVVSQGGYTHILGKGYVGQMGLVEESHLPGLKKLADAINAEGAMSIGQIMHTGRYGHAHEYGIHEAIAGGKTVGPEPVGPTAMSSPIKRYSPCREMTPEEIEEQIQAHIVAARMFKQTGWKGVEVCAIVGYLIADFLSRWTNKRTDKWGGSLENRARFLIEILKGIRKEVGDDYPLVMRLNSTDLIEGGNTDEEYIEIAKMCEAAVRIDLFSITVGWHESPGAAITAEKRPGDWLHLADNWKKAGIKAPICMAYRMNQPDVAEKAVAEGRIDIWEMCRPGIADPYLPKKVCEGRPEDIVTCTACNQGCFYYVFIDAIMGCMVNPRVGNEWDPAYAINPAAKKKKVLVVGAGPSGMECARLAAVRGHDVTIMEKSDSIGGEVKLGVKSPLLYDWAETIRYYKAQIDKLGIKLKLNTEATADSIKAEAPDVLVIATGGKPSRPKIEGIDNKIVTNVFDILEGKVKLGDKVVFIGGNEISIQTAEYVAEQGKEVTVLEKGKHICFDVNIFNILQHRRLMAKLNMKSMTNVTINEINDDGVEISTAGGKDVTIEADNVVVAEGMDADDALAKAVGTKIAPEVYSIGDCAGVRKLYEAIHDGYKMGVKIRGSLEV 6qkx A 2.40 BS02 FAD A 1 G415 G417 P418 S419 M437 E438 K439 G445 E446 W459 T481 A483 A499 T500 G501 F521 L524 E541 I542 Q545 L632 G648 D649 R654 K655 L656 G403 G405 P406 S407 M425 E426 K427 G433 E434 W447 T469 A471 A487 T488 G489 F509 L512 E529 I530 Q533 L620 G636 D637 R642 K643 L644 E1YD54 31061390 MYENLCKPIKIGNHLVKNRMKYAATVDNFCDTKNGNVIDREIEYLRERAKGGFGIVVSQGGYTHILGKGYVGQMGLVEESHLPGLKKLADAINAEGAMSIGQIMHTGRYGHAHEYGIHEAIAGGKTVGPEPVGPTAMSSPIKRYSPCREMTPEEIEEQIQAHIVAARMFKQTGWKGVEVCAIVGYLIADFLSRWTNKRTDKWGGSLENRARFLIEILKGIRKEVGDDYPLVMRLNSTDLIEGGNTDEEYIEIAKMCEAAVRIDLFSITVGWHESPGAAITAEKRPGDWLHLADNWKKAGIKAPICMAYRMNQPDVAEKAVAEGRIDIWEMCRPGIADPYLPKKVCEGRPEDIVTCTACNQGCFYYVFIDAIMGCMVNPRVGNEWDPAYAINPAAKKKKVLVVGAGPSGMECARLAAVRGHDVTIMEKSDSIGGEVKLGVKSPLLYDWAETIRYYKAQIDKLGIKLKLNTEATADSIKAEAPDVLVIATGGKPSRPKIEGIDNKIVTNVFDILEGKVKLGDKVVFIGGNEISIQTAEYVAEQGKEVTVLEKGKHICFDVNIFNILQHRRLMAKLNMKSMTNVTINEINDDGVEISTAGGKDVTIEADNVVVAEGMDADDALAKAVGTKIAPEVYSIGDCAGVRKLYEAIHDGYKMGVKIRG 6rhf A 1.07 BS01 FMN A 1 I52 T54 N84 A85 R86 L88 Q89 V98 R102 I105 I115 N117 N127 L129 I131 F144 V145 G146 Q148 I5 T7 N37 A38 R39 L41 Q42 V51 R55 I58 I68 N70 N80 L82 I84 F97 V98 G99 Q101 B8GAY9 ASGMIVTDAGADQPIVFVNRAFSTITGYAPNEVLGRNARFLQGPQTDAATVARLREAIAAARPIQERILNYRKDGQPFWNQLSISPVRDETGNVVAFVGVQTDVTA 6rhg A 1.22 BS01 FMN A 1 T54 N84 C85 R86 L88 Q89 V98 R102 I105 I115 N117 N127 L129 I131 F144 V145 G146 Q148 T7 N37 C38 R39 L41 Q42 V51 R55 I58 I68 N70 N80 L82 I84 F97 V98 G99 Q101 B8GAY9 ASGMIVTDAGADQPIVFVNRAFSTITGYAPNEVLGRNCRFLQGPQTDAATVARLREAIAAARPIQERILNYRKDGQPFWNQLSISPVRDETGNVVAFVGVQTDVT