5vud A 2.00 BS01 III C 1 Y7 Y59 E63 N66 M67 T73 N77 I80 Y84 I95 Y99 D114 Y123 T143 K146 W147 Q155 L156 Y159 L163 W167 Y171 Y7 Y59 E63 N66 M67 T73 N77 I80 Y84 I95 Y99 D114 Y123 T143 K146 W147 Q155 L156 Y159 L163 W167 Y171 P18465 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 5vue A 1.80 BS01 III C 1 Y7 M45 E63 N66 M67 T73 N77 I80 Y84 I95 Y99 D114 Y123 T143 K146 W147 V152 Q155 Y159 W167 Y171 Y7 M45 E63 N66 M67 T73 N77 I80 Y84 I95 Y99 D114 Y123 T143 K146 W147 V152 Q155 Y159 W167 Y171 P18465 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 5vuf A 1.90 BS01 III C 1 M5 Y7 M45 E63 N66 M67 Y74 N77 I80 Y84 Y99 S116 Y123 T143 K146 W147 V152 Q155 Y159 W167 Y171 M5 Y7 M45 E63 N66 M67 Y74 N77 I80 Y84 Y99 S116 Y123 T143 K146 W147 V152 Q155 Y159 W167 Y171 P18465 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 5vvp A 2.00 BS01 III C 1 M5 Y7 Y59 E63 N66 M67 S70 T73 Y74 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 M5 Y7 Y59 E63 N66 M67 S70 T73 Y74 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 I3ZN84 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 5vwd A 1.80 BS01 III C 1 M5 Y7 M45 Y59 E63 N66 M67 T73 Y74 E76 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 V152 Q155 Y159 W167 Y171 M5 Y7 M45 Y59 E63 N66 M67 T73 Y74 E76 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 V152 Q155 Y159 W167 Y171 I3ZN84 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 5vwf A 1.80 BS01 III C 1 Y7 M45 Y59 E63 N66 M67 T73 N77 I80 Y84 I95 Y99 Y116 Y123 T143 K146 W147 A150 V152 Q155 L156 Y159 W167 Y171 Y7 M45 Y59 E63 N66 M67 T73 N77 I80 Y84 I95 Y99 Y116 Y123 T143 K146 W147 A150 V152 Q155 L156 Y159 W167 Y171 I3ZN84 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 5vwj A 2.00 BS01 III C 1 Y7 Y59 E63 N66 M67 Y74 N77 I80 Y84 I95 R97 Y99 D114 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 Y7 Y59 E63 N66 M67 Y74 N77 I80 Y84 I95 R97 Y99 D114 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 P10319 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 5ybz A 1.71 BS01 CA C 1 T174 S216 T54 S96 Q9ESN4 APGDPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYADA 5yc6 U 1.18 BS01 PZH U 1 D189 S190 C191 Q192 S195 W215 G219 C220 G226 D192 S193 C194 Q195 S198 W218 G221 C222 G229 3.4.21.73 P00749 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK 5ygp A 2.09 BS01 MAL A 1 D15 K16 W63 A64 D66 R67 E112 E154 P155 Y156 F157 W231 W341 R345 D12 K13 W60 A61 D63 R64 E109 E151 P152 Y153 F154 W228 W338 R342 EEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAAAQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLEGCVEDLRSRLQRL 5ygp C 2.09 BS01 MAL C 1 D15 K16 W63 D66 E112 E154 P155 Y156 W231 W341 D10 K11 W58 D61 E107 E149 P150 Y151 W226 W336 GKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAAAQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLEGCVEDLRSRLQRLE 5ygp D 2.09 BS01 MAL D 1 D15 K16 W63 A64 D66 R67 E112 E154 P155 Y156 W231 W341 D12 K13 W60 A61 D63 R64 E109 E151 P152 Y153 W228 W338 EEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAAAQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLEGCVEDLRSRLQRLE 5ygs A 2.69 BS01 MLR A 1 D15 K16 E45 E46 W63 A64 D66 R67 E112 E154 P155 Y156 F157 W231 M331 W341 Y342 R345 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 M330 W340 Y341 R344 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAAAQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRLE 5ygs B 2.69 BS01 MLR B 1 N13 D15 K16 K43 E45 E46 W63 A64 D66 R67 E112 E154 P155 Y156 F157 W231 M331 W341 Y342 R345 N13 D15 K16 K43 E45 E46 W63 A64 D66 R67 E112 E154 P155 Y156 F157 W231 M331 W341 Y342 R345 MKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAAAQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRL 5yuv A 2.06 BS01 NUC G 1 W304 N308 W305 N309 2.7.7.7 Q47155 29850882 GSRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKFGRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDP 5yuv A 2.06 BS02 NUC H 1 W256 E260 R317 W257 E261 R318 2.7.7.7 Q47155 29850882 GSRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKFGRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDP 5zvc A 1.80 BS01 GAL A 1 W298 S357 T359 S360 N395 N397 T398 W74 S133 T135 S136 N171 N173 T174 A0A0D6CBA8 KPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTTQLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFRGILYGVLTQDNVSEGTGEAKNAKGVYISTTSGKFTPKIGSIGLHSITENVHPNQQSRFTPVGVAQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAFIDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGAYPLVVPPNGHFRFDSWVNQFYSLAPM 5zyn B 1.75 BS01 FMN B 1 K76 P162 W295 F297 L298 N359 F362 Y363 K46 P132 W265 F267 L268 N329 F332 Y333 1.3.1.6 P21375 ASMKQPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSGINGAHTDTQQNLKVMDTPELFLKDTLHSAKGRGVPSLMDKLTKESKSAIRWLQTEFDLKLDLLAQLGGHSVPRTHRSSGKLPPGFEIVQALSKKLKDISSKDSNLVQIMLNSEVVDIELDNQGHVTGVVYMDENGNRKIMKSHHVVFCSGGFGYSKEMLKEYSPNLIHLPTTNGKQTTGDGQKILSKLGAELIDMDQVQVHPTGFIDPNDRENNWKFLAAEALRGLGGILLHPTTGRRFTNELSTRDTVTMEIQSKCPKNDNRALLVMSDKVYENYTNNINFYMSKNLIKKVSINDLIRQYDLQTTASELVTELKSYSDVNTKDTFDRPLIINAFDKDISTESTVYVGEVTPVVHFTMGGVKINEKSQVIKKNSESVLSNGIFAAGEVSGGVHGANRLGGSSLLECVVFGKTAADNIAKLY 5zyn B 1.75 BS02 FAD B 1 I40 G41 G43 L44 A45 D65 K66 G72 N73 S74 A77 S78 S79 G80 S192 V194 C228 S229 G230 T252 Q256 D260 L298 H435 G466 E467 G480 S481 S482 L483 C486 I10 G11 G13 L14 A15 D35 K36 G42 N43 S44 A47 S48 S49 G50 S162 V164 C198 S199 G200 T222 Q226 D230 L268 H405 G436 E437 G450 S451 S452 L453 C456 1.3.1.6 P21375 ASMKQPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSGINGAHTDTQQNLKVMDTPELFLKDTLHSAKGRGVPSLMDKLTKESKSAIRWLQTEFDLKLDLLAQLGGHSVPRTHRSSGKLPPGFEIVQALSKKLKDISSKDSNLVQIMLNSEVVDIELDNQGHVTGVVYMDENGNRKIMKSHHVVFCSGGFGYSKEMLKEYSPNLIHLPTTNGKQTTGDGQKILSKLGAELIDMDQVQVHPTGFIDPNDRENNWKFLAAEALRGLGGILLHPTTGRRFTNELSTRDTVTMEIQSKCPKNDNRALLVMSDKVYENYTNNINFYMSKNLIKKVSINDLIRQYDLQTTASELVTELKSYSDVNTKDTFDRPLIINAFDKDISTESTVYVGEVTPVVHFTMGGVKINEKSQVIKKNSESVLSNGIFAAGEVSGGVHGANRLGGSSLLECVVFGKTAADNIAKLY 5zzf A 1.60 BS01 HEM A 1 T39 K42 Y43 R45 T67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 F138 T39 K42 Y43 R45 T67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 F138 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKYDRFKHLKTEAEMKASEDLKKDGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG 5zzg A 1.80 BS02 T6C A 1 L29 Y43 F46 D64 T67 V68 I107 L29 Y43 F46 D64 T67 V68 I107 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKYDRFKHLKTEAEMKASEDLKKDGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG 6a1f A 1.50 BS01 9OF A 1 I165 K167 F170 V173 A186 F238 E239 L241 L294 V306 I32 K34 F37 V40 A53 F105 E106 L108 L161 V173 2.7.12.1 Q13627 30217414 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKEYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTA 6a1g A 2.15 BS01 9OL A 1 G166 K167 V173 A186 F238 E239 M240 L241 E291 L294 V306 G33 K34 V40 A53 F105 E106 M107 L108 E158 L161 V171 2.7.12.1 Q13627 30217414 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKEYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 6a1g B 2.15 BS01 9OL B 1 G166 F170 V173 A186 F238 E239 L241 E291 V306 G32 F36 V39 A52 F104 E105 L107 E157 V172 2.7.12.1 Q13627 30217414 VYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 6a5l A 5.60 BS01 NUC P 1 I251 A252 M253 R447 D484 D486 I239 A240 M241 R435 D472 D474 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5l A 5.60 BS02 NUC T 1 A310 K333 R345 R351 Q448 T832 A833 Y837 E1410 A298 K321 R333 R339 Q436 T820 A821 Y825 E1361 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5l A 5.60 BS03 NUC N 1 K272 K318 N1108 A1110 K260 K306 N1083 A1085 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5l A 5.60 BS05 ZN A 2 C107 N109 G167 C168 C106 N108 G159 C160 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5l B 5.60 BS01 NUC P 1 G471 R490 P521 Q776 R884 R935 K987 H1097 V1111 R1124 G439 R458 P489 Q725 R833 R874 K926 H1036 V1050 R1063 2.7.7.6 C4QZQ7 DDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSG 6a5l B 5.60 BS02 NUC T 1 E420 R423 Y452 A455 T456 Q462 K500 R857 R942 R1122 R1129 E388 R391 Y420 A423 T424 Q430 K468 R806 R881 R1061 R1068 2.7.7.6 C4QZQ7 DDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSG 6a5l B 5.60 BS03 NUC N 1 R419 K463 L501 R387 K431 L469 2.7.7.6 C4QZQ7 DDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSG 6a5l C 5.60 BS01 ZN C 1 C85 C91 E93 C94 C82 C88 E90 C91 C4R7L2 EPKVNIINAQDDEVELMLSDVNLSLANSLRRTMLAEVPTLAIDLVEIKMNTSVLADEFISHRLGLIPLVSEDVEEMKYSRDCTCEDYCDECSVVLELSARHEGEEGTTDVYSSSLIKVSGPGNLNVGEPVRRDDYDQGILLCKLRNHQELNIRCIAKKGIAKEHAKWSPCSAIAFEYDPHNKLKHTDFWFEVDAKKEWPDSKYATWEEPPKPGEVFDYKAKPNRFYMTVETTGSLKANQVFSRGIKTLQEKLANVLFELENSR 6a5l I 5.60 BS01 ZN I 1 C75 C78 C103 N105 C73 C76 C101 N103 F2QPE6 SFRFCLECNNMLYPKEDKENQRLLYSCRNCDYTELAEDPKVYRHELITNIGETAGIVDDIGQDPTLPRSDKECPECHSRDCVFFQSQQRRKDTNMTLFYVCLNCKKTFRDE 6a5l I 5.60 BS02 ZN I 2 E9 C10 C32 E7 C8 C30 F2QPE6 SFRFCLECNNMLYPKEDKENQRLLYSCRNCDYTELAEDPKVYRHELITNIGETAGIVDDIGQDPTLPRSDKECPECHSRDCVFFQSQQRRKDTNMTLFYVCLNCKKTFRDE 6a5l L 5.60 BS01 ZN L 1 C33 C36 C50 E52 C53 C6 C9 C23 E25 C26 F2QMI1 GVKYTCGACAHNFSLNKSDPVRCKECGHRVIYKARTKRMIQFDAR 6a5l a 5.60 BS01 NUC T 1 R40 R42 R63 R72 R83 F84 Q85 R116 V117 T118 R3 R5 R26 R35 R46 F47 Q48 R79 V80 T81 P84243 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6a5l a 5.60 BS02 NUC N 1 P43 V46 R63 K64 L65 P66 R69 R83 P6 V9 R26 K27 L28 P29 R32 R46 P84243 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6a5l b 5.60 BS02 NUC N 1 R45 I46 S47 R78 K79 T80 R23 I24 S25 R56 K57 T58 P62805 RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 6a5l d 5.60 BS01 NUC T 1 R30 Y39 G50 I51 S53 R83 S84 T85 K122 R3 Y12 G23 I24 S26 R56 S57 T58 K95 P06899 RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6a5l e 5.60 BS01 NUC T 1 R40 Y41 G44 V46 R49 L65 P66 R69 R2 Y3 G6 V8 R11 L27 P28 R31 P84243 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 6a5l e 5.60 BS02 NUC N 1 R42 P43 T45 R63 R116 V117 T118 M120 R4 P5 T7 R25 R78 V79 T80 M82 P84243 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 6a5l f 5.60 BS02 NUC 0 1 R78 K79 T80 R54 K55 T56 P62805 NIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 6a5l g 5.60 BS01 NUC 0 1 R42 V43 A45 K75 T76 R77 R29 V30 A32 K62 T63 R64 P04908 AKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 6a5o A 9.90 BS01 NUC P 1 A252 M253 R447 D486 A240 M241 R435 D474 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5o A 9.90 BS02 NUC T 1 A310 K318 R327 K333 R345 R351 Q448 T832 A833 Y837 E1406 E1407 E1410 A298 K306 R315 K321 R333 R339 Q436 T820 A821 Y825 E1357 E1358 E1361 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5o A 9.90 BS03 NUC N 1 K101 W139 K272 K318 H1390 K100 W138 K260 K306 H1341 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5o A 9.90 BS05 ZN A 2 C107 C148 G167 C168 C106 C147 G159 C160 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5o A 9.90 BS06 MG A 1 D482 D484 D470 D472 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5o B 9.90 BS01 NUC P 1 G471 R490 P521 E522 K775 Q776 R884 K987 H1097 R1124 G439 R458 P489 E490 K724 Q725 R833 K926 H1036 R1063 2.7.7.6 C4QZQ7 DDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSG 6a5o B 9.90 BS02 NUC T 1 K201 R423 R427 Y452 A455 T456 Q462 Q524 R857 R942 G1121 R1122 L1128 R1129 K169 R391 R395 Y420 A423 T424 Q430 Q492 R806 R881 G1060 R1061 L1067 R1068 2.7.7.6 C4QZQ7 DDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSG 6a5o B 9.90 BS03 NUC N 1 R419 E461 K463 R387 E429 K431 2.7.7.6 C4QZQ7 DDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSG 6a5o C 9.90 BS01 ZN C 1 C85 C87 C91 E93 C82 C84 C88 E90 C4R7L2 EPKVNIINAQDDEVELMLSDVNLSLANSLRRTMLAEVPTLAIDLVEIKMNTSVLADEFISHRLGLIPLVSEDVEEMKYSRDCTCEDYCDECSVVLELSARHEGEEGTTDVYSSSLIKVSGPGNLNVGEPVRRDDYDQGILLCKLRNHQELNIRCIAKKGIAKEHAKWSPCSAIAFEYDPHNKLKHTDFWFEVDAKKEWPDSKYATWEEPPKPGEVFDYKAKPNRFYMTVETTGSLKANQVFSRGIKTLQEKLANVLFELENSR 6a5o I 9.90 BS01 ZN I 1 C75 E77 C78 C103 N105 C106 C73 E75 C76 C101 N103 C104 F2QPE6 SFRFCLECNNMLYPKEDKENQRLLYSCRNCDYTELAEDPKVYRHELITNIGETAGIVDDIGQDPTLPRSDKECPECHSRDCVFFQSQQRRKDTNMTLFYVCLNCKKTFRDE 6a5o L 9.90 BS01 ZN L 1 C33 A35 C36 C50 C6 A8 C9 C23 F2QMI1 GVKYTCGACAHNFSLNKSDPVRCKECGHRVIYKARTKRMIQFDAR 6a5o a 9.90 BS01 NUC T 1 R42 R63 R72 R83 F84 Q85 S86 R116 V117 T118 M120 R5 R26 R35 R46 F47 Q48 S49 R79 V80 T81 M83 P84243 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6a5o a 9.90 BS02 NUC N 1 H39 P43 G44 V46 A47 R49 K56 R63 K64 L65 P66 R69 R83 H2 P6 G7 V9 A10 R12 K19 R26 K27 L28 P29 R32 R46 P84243 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6a5o d 9.90 BS01 NUC T 1 R28 S29 R30 Y39 G50 I51 S53 R83 S84 T85 R1 S2 R3 Y12 G23 I24 S26 R56 S57 T58 P06899 RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6a5o g 9.90 BS01 NUC T 1 P26 R29 E41 R42 V43 G44 A45 T76 R77 P13 R16 E28 R29 V30 G31 A32 T63 R64 P04908 AKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 6a5o h 9.90 BS01 NUC T 1 S29 K31 E32 S33 Y37 T85 S1 K3 E4 S5 Y9 T57 P06899 SRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6a5o h 9.90 BS02 NUC N 1 R30 E32 G50 I51 S52 S53 R83 S84 T85 R2 E4 G22 I23 S24 S25 R55 S56 T57 P06899 SRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6a5p A 7.00 BS01 NUC P 1 I251 A252 M253 R447 D486 I239 A240 M241 R435 D474 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5p a 7.00 BS01 NUC T 1 R42 R63 R72 R83 F84 Q85 V117 T118 M120 R5 R26 R35 R46 F47 Q48 V80 T81 M83 P84243 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6a5p a 7.00 BS02 NUC N 1 H39 R40 P43 G44 V46 R63 K64 L65 R83 H2 R3 P6 G7 V9 R26 K27 L28 R46 P84243 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6a5p d 7.00 BS01 NUC T 1 R28 S29 R30 Y39 I51 S53 R83 S84 T85 R1 S2 R3 Y12 I24 S26 R56 S57 T58 P06899 RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6a5p e 7.00 BS02 NUC N 1 R40 R42 T45 R63 R72 R83 F84 R116 V117 T118 R2 R4 T7 R25 R34 R45 F46 R78 V79 T80 P84243 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 6a5p f 7.00 BS01 NUC T 1 R45 I46 S47 R78 K79 R21 I22 S23 R54 K55 P62805 NIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 6a5p g 7.00 BS01 NUC T 1 R29 R42 V43 A45 R16 R29 V30 A32 P04908 AKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 6a5p h 7.00 BS02 NUC N 1 R30 G50 I51 S52 R83 S84 T85 R2 G22 I23 S24 R55 S56 T57 P06899 SRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6a5r A 8.70 BS01 NUC P 1 A252 M253 R447 D484 D486 A240 M241 R435 D472 D474 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5r A 8.70 BS02 NUC T 1 A310 K318 K333 R345 R351 Q448 T832 A833 Y837 R1389 E1410 A298 K306 K321 R333 R339 Q436 T820 A821 Y825 R1340 E1361 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5r A 8.70 BS03 NUC N 1 K272 K318 H1390 K260 K306 H1341 2.7.7.6 C4R4Y0 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPKVVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6a5r B 8.70 BS01 NUC P 1 G471 R490 P521 Q776 K987 H1097 V1111 R1124 G439 R458 P489 Q725 K926 H1036 V1050 R1063 2.7.7.6 C4QZQ7 DDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSG 6a5r B 8.70 BS02 NUC T 1 E420 R423 Y452 A455 T456 Q462 D498 K500 Q524 R857 R942 R1122 R1129 E388 R391 Y420 A423 T424 Q430 D466 K468 Q492 R806 R881 R1061 R1068 2.7.7.6 C4QZQ7 DDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSG 6a5r B 8.70 BS03 NUC N 1 A220 R419 K463 K500 A188 R387 K431 K468 2.7.7.6 C4QZQ7 DDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSG 6a5r E 8.70 BS01 NUC N 1 I89 S118 I88 S117 C4R3P8 EDNNRIISRLWRSFRTVKEMAADRGYFISQEEMDQSLEEFRSKICDSMGNPQRKLMSFLANPTPEALEKYSDLGTLWVEFCDEPSVGIKTMRNFCLRIQEKNFSTGIFIYQNNITPSANKMIPTVSPAIIETFQESDLVVNITHHELVPKHIRLSDGEKSQLLQRYKLKESQLPRIQREDPVARYLGLKRGQVVKIIRRSETSGRYASYRICL 6a5r d 8.70 BS01 NUC T 1 R30 Y39 I51 S53 R83 S84 T85 R3 Y12 I24 S26 R56 S57 T58 P06899 RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6a5r e 8.70 BS02 NUC N 1 R40 R42 T45 R63 R83 F84 R116 V117 T118 R2 R4 T7 R25 R45 F46 R78 V79 T80 P84243 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 6a5u e 7.60 BS01 NUC T 1 R40 Y41 G44 V46 R49 L65 R2 Y3 G6 V8 R11 L27 P84243 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 6a5v e 6.90 BS01 NUC T 1 R40 Y41 G44 V46 R49 L65 R69 R2 Y3 G6 V8 R11 L27 R31 P84243 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 6a5v h 6.90 BS01 NUC 1 1 Y39 I51 S52 S53 Y9 I21 S22 S23 P06899 KESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6a96 B 3.51 BS01 ABU B 1 E155 Y157 F200 T202 Y205 E148 Y150 F193 T195 Y198 P28472 30140029 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFSQPARAAAIDRWSRIVFPFTFSLFNLVYWLYYV 6azy A 2.70 BS01 ADP A 1 P178 V179 I180 R182 G208 G210 K211 T212 A213 I345 P383 D384 I387 P162 V163 I164 R166 G192 G194 K195 T196 A197 I321 P359 D360 I363 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPSQDEMGHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERMFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINMIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6azy A 2.70 BS02 ADP A 2 H570 V572 T608 G609 C610 G611 K612 T613 L614 I775 R779 R816 H546 V548 T584 G585 C586 G587 K588 T589 L590 I722 R726 R763 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPSQDEMGHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERMFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINMIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6b4q A 1.60 BS01 CQG A 1 A119 G120 Y202 E203 G220 N245 A115 G116 Y198 E199 G216 N241 2.4.2.1 A0A0U3AGT1 VVANYENASMAADYIKRVSNVLPDIGIICGSGLGKLIEEIEERKVIPYINIPNFPKTTVAGHVGNLVLGSVGGRKIVAMQGRLHMYEGYSNQEIALPIRVMKLLGVRVLLITNLAGGINRKLKSGDFVLIKGHINFPGLGLNNVLVGPNQDEFGPRFPDLSNAYDRLLQQLALKIAQENDFQDLVHEGVYAFNGGPTYESPDESNMLLKLGCDVVGMSTVPEVIIACHCGIKVLAVSLIANNSILDAENDVSINHEKVLAVAEKRADLLQMWFKEIITRLP 6b4t A 1.51 BS01 CQJ A 1 L118 A119 G120 Y202 E203 G220 M221 A244 N245 V262 L114 A115 G116 Y198 E199 G216 M217 A240 N241 V258 2.4.2.1 A0A0U3AGT1 VVANYENASMAADYIKRVSNVLPDIGIICGSGLGKLIEEIEERKVIPYINIPNFPKTTVAGHVGNLVLGSVGGRKIVAMQGRLHMYEGYSNQEIALPIRVMKLLGVRVLLITNLAGGINRKLKSGDFVLIKGHINFPGLGLNNVLVGPNQDEFGPRFPDLSNAYDRLLQQLALKIAQENDFQDLVHEGVYAFNGGPTYESPDESNMLLKLGCDVVGMSTVPEVIIACHCGIKVLAVSLIANNSILDAENDVSINHEKVLAVAEKRADLLQMWFKEIITRLP 6b56 A 1.42 BS01 CQV A 1 I53 K60 T61 T62 I49 K56 T57 T58 2.4.2.1 A0A0U3AGT1 VVANYENASMAADYIKRVSNVLPDIGIICGSGLGKLIEEIEERKVIPYINIPNFPKTTVAGHVGNLVLGSVGGRKIVAMQGRLHMYEGYSNQEIALPIRVMKLLGVRVLLITNLAGGINRKLKSGDFVLIKGHINFPGLGLNNVLVGPNQDEFGPRFPDLSNAYDRLLQQLALKIAQENDFQDLVHEGVYAFNGGPTYESPDESNMLLKLGCDVVGMSTVPEVIIACHCGIKVLAVSLIANNSILDAENDVSINHEKVLAVAEKRADLLQMWFKEIITRLP 6b5z A 2.30 BS02 ASP A 1 R11 A14 E125 R11 A14 E125 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b5z A 2.30 BS03 ASP A 2 R29 G93 P95 Y97 R29 G93 P95 Y97 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b5z A 2.30 BS04 ASP A 3 N151 K164 R165 N151 K164 R165 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b5z A 2.30 BS05 INS A 1 D82 D85 Y155 G170 S171 A172 R191 D200 D82 D85 Y155 G170 S171 A172 R191 D200 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b5z B 2.30 BS03 ASP B 2 R11 G15 Y116 Y118 E125 R11 G15 Y116 Y118 E125 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b60 A 2.70 BS01 GLU A 1 R11 R18 Y118 E125 R11 R18 Y118 E125 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b60 A 2.70 BS03 MG A 2 D46 E67 E68 D82 P83 L84 D46 E67 E68 D82 P83 L84 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b60 A 2.70 BS05 GLU B 1 K43 F88 R92 K43 F88 R92 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b60 B 2.70 BS01 GLU A 3 K43 R92 K43 R92 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b60 B 2.70 BS03 GLU B 2 R11 G15 E125 R11 G15 E125 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b60 B 2.70 BS04 MG B 1 D82 D85 R197 D200 D82 D85 R197 D200 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b61 A 2.70 BS01 MG A 1 D38 T40 P41 E67 E68 D38 T40 P41 E67 E68 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b61 A 2.70 BS02 ASP A 1 R11 A14 G15 E125 R11 A14 G15 E125 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b61 A 2.70 BS03 ASP A 2 R29 G93 Y97 R29 G93 Y97 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b61 A 2.70 BS04 ASP A 3 D85 Y155 A172 R191 R197 D85 Y155 A172 R191 R197 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b61 A 2.70 BS07 ASP B 1 T87 F88 T87 F88 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b61 A 2.70 BS08 ASP B 2 T122 D124 T122 D124 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b61 B 2.70 BS06 ASP B 4 R11 A14 Y118 E125 R11 A14 Y118 E125 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b61 B 2.70 BS08 ASP B 6 D85 Y155 G170 A172 R191 D85 Y155 G170 A172 R191 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b62 A 2.00 BS01 GLU A 1 A14 G15 R18 Y116 Y118 E125 A14 G15 R18 Y116 Y118 E125 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b62 A 2.00 BS02 GLU A 2 R18 L120 A121 R18 L120 A121 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b62 A 2.00 BS06 GLU A 4 R29 G93 P95 Y97 A121 R29 G93 P95 Y97 A121 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b62 A 2.00 BS07 GLU B 1 P41 K43 P41 K43 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b62 B 2.00 BS03 GLU B 3 R11 G15 Y118 E125 R11 G15 Y118 E125 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b62 B 2.00 BS04 GLU B 4 R18 L120 A121 T122 G123 R18 L120 A121 T122 G123 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b63 A 2.70 BS02 MG A 1 D46 E67 E68 T87 D46 E67 E68 T87 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b63 A 2.70 BS07 CU7 B 1 D85 F88 Y156 A172 R191 D85 F88 Y156 A172 R191 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b63 B 2.70 BS02 CU7 A 4 D85 T87 F88 Y156 R191 D85 T87 F88 Y156 R191 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b64 A 2.60 BS01 ASP A 1 R11 E125 R11 E125 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLREAVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b64 A 2.60 BS02 ASP A 2 D85 G170 S171 A172 R191 D200 D85 G170 S171 A172 R191 D200 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLREAVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b64 A 2.60 BS09 ASP B 2 F88 Y156 F88 Y156 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLREAVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b64 B 2.60 BS02 ASP A 6 F88 Y156 R191 F88 Y156 R191 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLREAVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b64 B 2.60 BS06 ASP B 5 D85 Y155 G170 A172 R191 L196 D200 D85 Y155 G170 A172 R191 L196 D200 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLREAVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b64 B 2.60 BS09 MG B 3 E67 D82 D85 R197 D200 E67 D82 D85 R197 D200 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLREAVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b65 B 2.70 BS02 MG B 2 T40 D46 E67 E68 T40 D46 E67 E68 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATQGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFERMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b66 A 2.50 BS02 GLU A 2 R18 Y118 A121 T122 R18 Y118 A121 T122 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATQGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFERMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b66 B 2.50 BS01 GLU B 1 R11 Y116 Y118 E125 R11 Y116 Y118 E125 3.1.3.11,3.1.3.25 O30298 MDERDALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKERVTVVTEESGVLGEGDVFVALDPLDGTFNATQGIPVYSVSLCFSYSDKLKDAFFGYVYNLATGDEYYADSSGAYRNGERIEVSDAEELYCNAIIYYPDRKFPFERMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESLGNKKFDMQERLNIVAANEKLHPKLLELIK 6b6v A 2.50 BS01 SF4 A 1 C51 N53 C54 M56 G57 C59 G72 V73 C74 I81 R84 M203 C48 N50 C51 M53 G54 C56 G69 V70 C71 I78 R81 M200 1.2.7.4 Q72A99 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFCELGTTCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLT 6b6v A 2.50 BS02 XCC A 1 H266 C301 C302 H319 C340 G447 C448 C478 C519 Y553 S554 K556 H263 C298 C299 H316 C337 G444 C445 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFCELGTTCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLT 6b6v A 2.50 BS03 FES B 1 C42 F44 C45 T50 R60 C39 F41 C42 T47 R57 1.2.7.4 Q72A99 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFCELGTTCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLT 6b6w A 1.72 BS02 XCC A 1 H266 C301 C302 H319 C340 C448 G477 C478 C519 Y553 S554 K556 H263 C298 C299 H316 C337 C445 G474 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFCELGTTCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6b6w A 1.72 BS03 CUV A 1 H266 C301 C302 C340 V446 G447 C448 G477 C478 C519 Y553 S554 K556 H263 C298 C299 C337 V443 G444 C445 G474 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFCELGTTCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6b6y A 2.60 BS03 FES B 1 C42 F44 C45 T50 C35 F37 C38 T43 1.2.7.4 Q72A99 RSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFCELGTTCRNCIMGPCRIANKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQADAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6b75 A 2.53 BS01 CVP A 1 H191 F193 D219 V242 A244 P273 S275 T304 Q305 P307 I309 R311 I351 A379 H173 F175 D201 V224 A226 P255 S257 T286 Q287 P289 I291 R293 I333 A361 2.4.2.12 P43490 FNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNI 6b75 B 2.53 BS01 CVP B 1 H191 F193 R196 D219 V242 A244 P273 S275 Q305 P307 R311 I351 A379 H174 F176 R179 D202 V225 A227 P256 S258 Q288 P290 R294 I334 A362 2.4.2.12 P43490 FNILLATDSYKVTHYKQYPPNTSKVYSYFECREKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNI 6b76 A 2.44 BS01 CVJ A 1 Y188 H191 F193 R196 D219 V242 A244 S275 R311 I351 A379 Y173 H176 F178 R181 D204 V227 A229 S260 R296 I336 A364 2.4.2.12 P43490 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIE 6b76 C 2.44 BS01 CVJ C 1 Y188 H191 F193 R196 D219 Y240 V242 A244 A245 S275 R311 I351 A379 Y172 H175 F177 R180 D203 Y224 V226 A228 A229 S259 R295 I335 A363 2.4.2.12 P43490 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIE 6b76 D 2.44 BS01 CVJ D 1 Y188 H191 F193 R196 D219 Y240 S241 V242 A244 S275 R311 I351 A379 Y175 H178 F180 R183 D206 Y227 S228 V229 A231 S262 R298 I338 A366 2.4.2.12 P43490 AEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTEKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNI 6b80 A 1.95 BS02 MYR B 1 V31 Y121 K123 P125 V30 Y111 K113 P114 Q9I834 29287778 SLFELGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYRYNYLKPFCKKADPC 6b80 B 1.95 BS01 MYR B 1 L2 L5 I9 Y22 C29 G30 C45 H48 K49 L2 L5 I9 Y21 C28 G29 C44 H47 K48 Q9I834 29287778 SLFELGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYRYNYLKPFCKKADPC 6b81 B 1.76 BS01 OCA B 1 L5 I9 P18 A19 Y22 C29 G30 C45 H48 K49 L5 I9 P17 A18 Y21 C28 G29 C44 H47 K48 Q9I834 29287778 SLFELGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYRYNYLKPFCKKADPC 6b81 A 1.76 BS01 OCA A 1 L2 L5 P18 A19 Y22 N28 C29 G30 C45 H48 K49 L2 L5 P17 A18 Y21 N27 C28 G29 C44 H47 K48 Q9I834 29287778 SLFELGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYRYNYLKPFCKKADPC 6b83 B 1.70 BS01 6NA B 1 Y21 C28 G29 C44 H47 Y21 C28 G29 C44 H47 Q9I834 29287778 SLFELGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYRYNYLKPACKKADPC 6bdp A 1.43 BS02 DE4 A 1 P16 H37 M38 F39 D91 L92 V127 V128 I140 D144 L147 F153 T157 M233 L236 P18 H39 M40 F41 D86 L87 V122 V123 I135 D139 L142 F148 T152 M228 L231 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDLI 6bdq A 1.83 BS02 DE7 A 1 R17 M38 F39 I42 D91 V127 V128 I140 D144 L147 F153 N228 M233 R19 M40 F41 I44 D93 V129 V130 I142 D146 L149 F155 N230 M235 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTPPPLTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDLI 6bdr A 1.66 BS02 DF7 A 1 P16 H37 M38 D91 L92 V127 V128 K137 I140 E141 D144 F153 T157 E158 P18 H39 M40 D93 L94 V129 V130 K139 I142 E143 D146 F155 T159 E160 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTPPPLTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDLI 6bdr A 1.66 BS03 DF7 A 2 L68 Y76 N103 L70 Y78 N105 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTPPPLTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDLI 6bds A 1.53 BS02 DJ4 A 1 R17 H37 M38 F39 I42 F43 D91 V127 V128 I140 D144 L147 F153 T157 M233 L236 R19 H39 M40 F41 I44 F45 D93 V129 V130 I142 D146 L149 F155 T159 M235 L238 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTPPPLTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDL 6bds A 1.53 BS03 DJ4 A 2 P65 L68 Y76 N103 P106 P67 L70 Y78 N105 P108 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTPPPLTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDL 6bmc A 2.70 BS01 PEP A 1 R106 K113 P114 G216 E217 K240 R271 H303 R106 K113 P114 G207 E208 K231 R262 H294 2.5.1.54 G3XCJ9 30242059 MDDLLQRVRRCEALQQPEWGDPSRLRDVQAYLRGSPALIRAGDILALRATLARVARGEALVVQCGDCAEDMDDHHAENVARKAAVLELLAGALRLAGRRPVIRVGRIAGQYAKPRSKPHEQTLPVYRGDMVNGREAHAEQRRADPQRILKGYAAARNIMRHLGWDAASASPVWTSHEMLLLDYELSMLREDEQRRVYLGSTHWPWIGERTRQVDGAHVALLAEVLNPVACKVGPEIGRDQLLALCERLDPRREPGRLTLIARMGAQKVGERLPPLVEAVRAAGHPVIWLSDPMHGNTIVAPCGNKTRLVRSIAEEVAAFRLAVSGSGGVAAGLHLETTPDDVTECVADSSGLHQVSRHYTSLCDPRLNPWQALSAVMAWS 6bmc A 2.70 BS02 CO A 1 C67 K113 H303 E345 D373 C67 K113 H294 E336 D364 2.5.1.54 G3XCJ9 30242059 MDDLLQRVRRCEALQQPEWGDPSRLRDVQAYLRGSPALIRAGDILALRATLARVARGEALVVQCGDCAEDMDDHHAENVARKAAVLELLAGALRLAGRRPVIRVGRIAGQYAKPRSKPHEQTLPVYRGDMVNGREAHAEQRRADPQRILKGYAAARNIMRHLGWDAASASPVWTSHEMLLLDYELSMLREDEQRRVYLGSTHWPWIGERTRQVDGAHVALLAEVLNPVACKVGPEIGRDQLLALCERLDPRREPGRLTLIARMGAQKVGERLPPLVEAVRAAGHPVIWLSDPMHGNTIVAPCGNKTRLVRSIAEEVAAFRLAVSGSGGVAAGLHLETTPDDVTECVADSSGLHQVSRHYTSLCDPRLNPWQALSAVMAWS 6bmc B 2.70 BS02 PEP B 1 R106 K113 E186 W214 G216 E217 K240 R271 H303 R106 K113 E177 W205 G207 E208 K231 R262 H294 2.5.1.54 G3XCJ9 30242059 MDDLLQRVRRCEALQQPEWGDPSRLRDVQAYLRGSPALIRAGDILALRATLARVARGEALVVQCGDCAEDMDDHHAENVARKAAVLELLAGALRLAGRRPVIRVGRIAGQYAKPRSKPHEQEQTLPVYRGDMVNGREAHAEQRRADPQRILKGYAAARNIMRHLGWDAASPVWTSHEMLLLDYELSMLREDEQRRVYLGSTHWPWIGERTRQVDGAHVALLAEVLNPVACKVGPEIGRDQLLALCERLDPRREPGRLTLIARMGAQKVGERLPPLVEAVRAAGHPVIWLSDPMHGNTIVAPCGNKTRLVRSIAEEVAAFRLAVSGSGGVAAGLHLETTPDDVTECVADSSGLHQVSRHYTSLCDPRLNPWQALSAVMAWS 6bxj A 2.09 BS01 MG A 1 S121 S123 D221 S121 S123 D221 P05106 30209215 GPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKWKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECP 6d26 A 2.80 BS01 FSY A 1 M17 F87 F90 F111 F112 R170 M181 C182 Y183 Y184 Y2262 W2283 L2286 P2287 T2290 M13 F83 F86 F107 F108 R166 M177 C178 Y179 Y180 Y382 W403 L406 P407 T410 Q9Y5Y4 ATLKPLCPILEQMSRLQSHSATSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCRMRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQAALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRADLGLQHRNIFEMLRIDEGGGSGGDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYRRRPGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVANPVLYVLTCPDMLRKLRRSLRTVLESVL 6d27 A 2.74 BS01 FT4 A 1 M17 F111 R170 Y183 Y184 Y2262 W2283 T2290 M13 F103 R162 Y175 Y176 Y378 W399 T406 Q9Y5Y4 ATLKPLCPILEQMSRLATSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCRMRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQAALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRADLGLQHRNIFEMLRIDEGGGSGGDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYRRRPGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVANPVLYVLTCPDMLRKLRRSLRTVLESVL 6d2b A 2.04 BS01 III C 1 M5 Y7 Y59 E63 N66 M67 Y99 Q155 Y159 W167 Y171 M5 Y7 Y59 E63 N66 M67 Y99 Q155 Y159 W167 Y171 P18465 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 6d2b A 2.04 BS02 III C 2 T73 Y74 N77 I80 Y84 I95 D114 Y123 T143 K146 W147 V152 T73 Y74 N77 I80 Y84 I95 D114 Y123 T143 K146 W147 V152 P18465 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 6d2r A 1.83 BS01 III C 1 Y7 E63 N66 M67 E76 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 Y7 E63 N66 M67 E76 N77 I80 Y84 I95 Y99 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 P18465 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 6da6 A 2.59 BS01 MG A 1 M220 E228 M221 E229 4.1.1.- C6ZCR8 30152678 SMKRLKDLREYLAVLEAHQDVREIDEPVDPHLEAGAAARWTYENRGPALMLNDLTGTGRFCRILAAPAGLSTIPGSPLARVALSLGLDVSATAHEIVDSLAAARTREPVAPVVVDSAPCQDNVLLGDDANLDRFPAPLLHEGDGGPYLNTWGTIIVSTPDGSFTNWAIARVMKIDGKRMTGTFIPTQHLGQIRKLWDNLGQPMPFAIVQGTEPGIPFVASMPLPDGIEEVGFLGAYFGEPLELVRAKTVDLLVPASAEIVIEGHVMPGPEYVVDAITYRDDPIWPISVAGEPVDETHTAWGLVTAAEALALLRAAKLPVATAWMPFEAAAHWLIVCLTEDWRERMPGLSRDGICLRISQVLAATRIEAMMTRVFVLDDDVDPSDQTELAWAIATRVSPAHGRLVRHGMINPLAGCYSAEERRLGYGPKAVLNGLLPPMAERSRRSSFRHTYPEPVRQRVIELLA 6da6 B 2.59 BS01 MG B 1 N164 M220 E228 N165 M221 E229 4.1.1.- C6ZCR8 30152678 SMKRLKDLREYLAVLEAHQDVREIDEPVDPHLEAGAAARWTYENRGPALMLNDLTGTGRFCRILAAPAGLSTIPGSPLARVALSLGLDVSATAHEIVDSLAAARTREPVAPVVVDSAPCQDNVLLGDDANLDRFPAPLLHEGDGGPYLNTWGTIIVSTPDGSFTNWAIARVMKIDGKRMTGTFIPTQHLGQIRKLWDNLGQPMPFAIVQGTEPGIPFVASMPLPDGIEEVGFLGAYFGEPLELVRAKTVDLLVPASAEIVIEGHVMPGPEYVVDAITYRDDPIWPISVAGEPVDETHTAWGLVTAAEALALLRAAKLPVATAWMPFEAAAHWLIVCLTEDWRERMPGLSRDGICLRISQVLAATRIEAMMTRVFVLDDDVDPSDQTELAWAIATRVSPAHGRLVRHGMINPLAGCYSAEERRLGYGPKAVLNGLLPPMAERSRRSSFRHTYPEPVRQRVIELLA 6da6 D 2.59 BS01 MG D 1 A218 M220 E228 A217 M219 E227 4.1.1.- C6ZCR8 30152678 KRLKDLREYLAVLEAHQDVREIDEPVDPHLEAGAAARWTYENRGPALMLNDLTGTGRFCRILAAPAGLSTIPGSPLARVALSLGLDVSATAHEIVDSLAAARTREPVAPVVVDSAPCQDNVLLGDDANLDRFPAPLLHEGDGGPYLNTWGTIIVSTPDGSFTNWAIARVMKIDGKRMTGTFIPTQHLGQIRKLWDNLGQPMPFAIVQGTEPGIPFVASMPLPDGIEEVGFLGAYFGEPLELVRAKTVDLLVPASAEIVIEGHVMPPEYVVDAITYRDDPIWPISVAGEPVDETHTAWGLVTAAEALALLRAAKLPVATAWMPFEAAAHWLIVCLTEDWRERMPGLSRDGICLRISQVLAATRIEAMMTRVFVLDDDVDPSDQTELAWAIATRVSPAHGRLVRHGMINPLAGCYSAEERRLGYGPKAVLNGLLPPMAERSRRSSFRHTYPEPVRQRVIELLA 6da9 A 2.05 BS01 FMN A 1 T149 N164 A166 I167 A168 R169 I183 Q186 H187 A218 S219 M220 P221 E228 S308 E316 W321 R386 T150 N165 A167 I168 A169 R170 I184 Q187 H188 A219 S220 M221 P222 E229 S286 E294 W299 R364 4.1.1.- C6ZCR8 30152678 SMKRLKDLREYLAVLEAHQDVREIDEPVDPHLEAGAAARWTYENRGPALMLNDLTGTGRFCRILAAPAGLSTIPGSPLARVALSLGLDVSATAHEIVDSLAAARTREPVAPVVVDSAPCQDNVLLGDDANLDRFPAPLLHEGDGGPYLNTWGTIIVSTPDGSFTNWAIARVMKIDGKRMTGTFIPTQHLGQIRKLWDNLGQPMPFAIVQGTEPGIPFVASMPLPDGIEEVGFLGAYFGEPLELVRAKTVDLLVPASAEIVIEGHVMPPEYVVDAITYRDDPIWPISVAGEPVDETHTAWGLVTAAEALALLRAAKLPVATAWMPFEAAAHWLIVCLTEDWRERMPGLSRDGICLRISQVLAATRIEAMMTRVFVLDDDVDPSDQTELAWAIATRVSPAHGRLVRHGMINPLAGCYSAEERRLGYGPKAVLNGLLPPMAERSRRSSFRHTYPEPVRQRVIELLA 6da9 A 2.05 BS02 MN A 1 N164 H187 E228 N165 H188 E229 4.1.1.- C6ZCR8 30152678 SMKRLKDLREYLAVLEAHQDVREIDEPVDPHLEAGAAARWTYENRGPALMLNDLTGTGRFCRILAAPAGLSTIPGSPLARVALSLGLDVSATAHEIVDSLAAARTREPVAPVVVDSAPCQDNVLLGDDANLDRFPAPLLHEGDGGPYLNTWGTIIVSTPDGSFTNWAIARVMKIDGKRMTGTFIPTQHLGQIRKLWDNLGQPMPFAIVQGTEPGIPFVASMPLPDGIEEVGFLGAYFGEPLELVRAKTVDLLVPASAEIVIEGHVMPPEYVVDAITYRDDPIWPISVAGEPVDETHTAWGLVTAAEALALLRAAKLPVATAWMPFEAAAHWLIVCLTEDWRERMPGLSRDGICLRISQVLAATRIEAMMTRVFVLDDDVDPSDQTELAWAIATRVSPAHGRLVRHGMINPLAGCYSAEERRLGYGPKAVLNGLLPPMAERSRRSSFRHTYPEPVRQRVIELLA 6dc2 A 1.99 BS04 FE A 1 H266 C302 C519 H263 C299 C516 1.2.7.4 Q72A99 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFCELGTTCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLSCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLT 6dc2 B 1.99 BS04 FE B 1 C302 C519 C299 C516 1.2.7.4 Q72A99 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFCELGTTCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLSCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLT 6dei A 1.70 BS01 III C 1 V73 D76 L77 E79 Y80 N83 V84 R85 H87 D99 S101 Q102 G103 Y113 I115 D117 K139 Q140 R141 V4 D7 L8 E10 Y11 N14 V15 R16 H18 D30 S32 Q33 G34 Y39 I41 D43 K65 Q66 R67 P25651 NSEVIKDLYEYLCNVRVHKSYEDDSGLWFDISQGTHSDYSIMDYKLGFVKGQAQVTEVIYAPVLKQRSTEELYSLQSKLPEYLFETLSFPLSSLNQFYNKIAKSLNK 6dei B 1.70 BS01 III C 1 F122 T130 L165 F52 T54 L89 P25651 SEVIKDLYEYLCNVRVHKSYEDDSGLWFDISQGTHSGGSSDDYSIMDYKLGFVTEVIYAPVLKQRSTEELYSLQSKLPEYLFETLSFPLSSLNQFYNKIAKSLNK 6dei B 1.70 BS02 III D 1 E72 D76 E79 Y80 N83 V84 R85 H87 D99 I100 S101 Q102 G103 Y113 I115 D117 Y118 K119 V137 Q140 R141 E2 D6 E9 Y10 N13 V14 R15 H17 D29 I30 S31 Q32 G33 Y43 I45 D47 Y48 K49 V61 Q64 R65 P25651 SEVIKDLYEYLCNVRVHKSYEDDSGLWFDISQGTHSGGSSDDYSIMDYKLGFVTEVIYAPVLKQRSTEELYSLQSKLPEYLFETLSFPLSSLNQFYNKIAKSLNK 6dik A 1.93 BS01 GKP A 1 F3 G6 K7 P18 F3 G6 K7 P17 Q90249 SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKADPC 6dlh A 2.20 BS01 CA A 1 F327 D330 R332 N335 D336 F299 D302 R304 N307 D308 Q08I46 QVPDPNQGLRAEWMRGALGMLWLPERTFNGNIEGIRIDDFLTQIKDIRTVDYVQLPLTSPNIFSPTHVAPHPIIESLWQGDTDANGDPINLVAPRESVDDPLLSWLKALRAAGLRTEIYVNSYNLLARIPEDTQADYPDVSARWMEWCDTNTEAQAFINSQTYHEGNGRRKYMFCYAEFILKEYAQRYGDLIDAWCFDSADNVMEDECGDDPASEDVNDQRIYQAFADACHAGNPNAAIAFNNSVGDREGNPFTSATLFDDYTFGHPFGGAGNMVVPEALYTYNHDLVVFMQTNNGYAFRDDTRTWNDNVVAHFFPKQSTTSWNAGNTPCLTDEQFVEWTSTGIVNGGGITWGTPLVRTNLENAPVLTLQPYALNQFELTDTYLKEFQSPGKPNWSRQYTILPAIYPGQPYSHNLVEGVDFWDPEGVGITGLTASGTLPAWLTISQTATGTWTLSGTPPVSEASNYTFELMAQDSDGVTNREVKLEVISHPAGFTNPGDGTPVWFSNPMVLAKATALKDYGSLLKLGVDFYDFEGDVLTITKTSGPDWLVLTQNSDDTWRLSGMPTAADAGENSFTFNVSDGILSSDTEIKITVDHVAGFTNLGNGAPVWSSPILNLTDGKGSFAYNYTLQLGTDYYDFEGDALTITKTSGPDWLTIQQTDANSWKLSGTPINSDAGENSFTFNLSDDTNSTTAEILINVIATI 6dlh A 2.20 BS02 CA A 2 G634 D666 E668 D670 D715 G606 D638 E640 D642 D687 Q08I46 QVPDPNQGLRAEWMRGALGMLWLPERTFNGNIEGIRIDDFLTQIKDIRTVDYVQLPLTSPNIFSPTHVAPHPIIESLWQGDTDANGDPINLVAPRESVDDPLLSWLKALRAAGLRTEIYVNSYNLLARIPEDTQADYPDVSARWMEWCDTNTEAQAFINSQTYHEGNGRRKYMFCYAEFILKEYAQRYGDLIDAWCFDSADNVMEDECGDDPASEDVNDQRIYQAFADACHAGNPNAAIAFNNSVGDREGNPFTSATLFDDYTFGHPFGGAGNMVVPEALYTYNHDLVVFMQTNNGYAFRDDTRTWNDNVVAHFFPKQSTTSWNAGNTPCLTDEQFVEWTSTGIVNGGGITWGTPLVRTNLENAPVLTLQPYALNQFELTDTYLKEFQSPGKPNWSRQYTILPAIYPGQPYSHNLVEGVDFWDPEGVGITGLTASGTLPAWLTISQTATGTWTLSGTPPVSEASNYTFELMAQDSDGVTNREVKLEVISHPAGFTNPGDGTPVWFSNPMVLAKATALKDYGSLLKLGVDFYDFEGDVLTITKTSGPDWLVLTQNSDDTWRLSGMPTAADAGENSFTFNVSDGILSSDTEIKITVDHVAGFTNLGNGAPVWSSPILNLTDGKGSFAYNYTLQLGTDYYDFEGDALTITKTSGPDWLTIQQTDANSWKLSGTPINSDAGENSFTFNLSDDTNSTTAEILINVIATI 6dlh A 2.20 BS04 CA A 4 T77 D79 T49 D51 Q08I46 QVPDPNQGLRAEWMRGALGMLWLPERTFNGNIEGIRIDDFLTQIKDIRTVDYVQLPLTSPNIFSPTHVAPHPIIESLWQGDTDANGDPINLVAPRESVDDPLLSWLKALRAAGLRTEIYVNSYNLLARIPEDTQADYPDVSARWMEWCDTNTEAQAFINSQTYHEGNGRRKYMFCYAEFILKEYAQRYGDLIDAWCFDSADNVMEDECGDDPASEDVNDQRIYQAFADACHAGNPNAAIAFNNSVGDREGNPFTSATLFDDYTFGHPFGGAGNMVVPEALYTYNHDLVVFMQTNNGYAFRDDTRTWNDNVVAHFFPKQSTTSWNAGNTPCLTDEQFVEWTSTGIVNGGGITWGTPLVRTNLENAPVLTLQPYALNQFELTDTYLKEFQSPGKPNWSRQYTILPAIYPGQPYSHNLVEGVDFWDPEGVGITGLTASGTLPAWLTISQTATGTWTLSGTPPVSEASNYTFELMAQDSDGVTNREVKLEVISHPAGFTNPGDGTPVWFSNPMVLAKATALKDYGSLLKLGVDFYDFEGDVLTITKTSGPDWLVLTQNSDDTWRLSGMPTAADAGENSFTFNVSDGILSSDTEIKITVDHVAGFTNLGNGAPVWSSPILNLTDGKGSFAYNYTLQLGTDYYDFEGDALTITKTSGPDWLTIQQTDANSWKLSGTPINSDAGENSFTFNLSDDTNSTTAEILINVIATI 6dms A 2.85 BS01 CA A 1 F327 R328 D330 R332 N335 D336 F298 R299 D301 R303 N306 D307 Q08I46 VPDPNQGLRAEWMRGALGMLWLPERTFNGNIEGIRIDDFLTQIKDIRTVDYVQLPLTSPNIFSPTHVAPHPIIESLWQGDTDANGDPINLVAPRESVDDPLLSWLKALRAAGLRTEIYVNSYNLLARIPEDTQADYPDVSARWMEWCDTNTEAQAFINSQTYHEGNGRRKYMFCYAEFILKEYAQRYGDLIDAWCFDSADNVMEDECGDDPASEDVNDQRIYQAFADACHAGNPNAAIAFNNSVGDREGNPFTSATLFDDYTFGQPFGGAGNMVVPEALYTYNHDLVVFMQTNNGYAFRDDTRTWNDNVVAHFFPKQSTTSWNAGNTPCLTDEQFVEWTSTGIVNGGGITWGTPLVRTNLENAPVLTLQPYALNQFELTDTYLKEFQSPGKPNWSRQYTILPAIYPGQPYSHNLVEGVDFWDPEGVGITGLTASGTLPAWLTISQTATGTWTLSGTPPVSEASNYTFELMAQDSDGVTNREVKLEVISHPAGFTNPGDGTPVWFSNPMVLAKATALKDYGSLLKLGVDFYDFEGDVLTITKTSGPDWLVLTQNSDDTWRLSGMPTAADAGENSFTFNVSDGILSSDTEIKITVDHVAGFTNLGNGAPVWSSPILNLTDGKGSFAYNYTLQLGTDYYDFEGDALTITKTSGPDWLTIQQTDANSWKLSGTPINSDAGENSFTFNLSDDTNSTTAEILINVIATI 6dns A 2.24 BS02 CA A 2 T77 D79 Q416 T47 D49 Q386 Q08I46 PDPNQGLRAEWMRGALGMLWLPERTFNGNIEGIRIDDFLTQIKDIRTVDYVQLPLTSPNIFSPTHVAPHPIIESLWQGDTDANGDPINLVAPRESVDDPLLSWLKALRAAGLRTEIYVNSYNLLARIPEDTQADYPDVSARWMEWCDTNTEAQAFINSQTYHEGNGRRKYMFCYAEFILKEYAQRYGDLIDAWCFDSADNVMEDECGDDPASEDVNDQRIYQAFADACHAGNPNAAIAFNNSVGDREGNPFTSATLFDDYTFGHPFGGAGNMVVPEALYTYNHDLVVFMQTNNGYAFRDDTRTWNDNVVAHFFPKQSTTSWNAGNTPCLTDEQFVEWTSTGIVNGGGITWGTPLVRTNLENAPVLTLQPYALNQFELTDTYLKEFQSPGKPNWSRQYTILPAIYPGQPYSHNLVEGVDFWDPEGVGITGLTASGTLPAWLTISQTATGTWTLSGTPPVSEASNYTFELMAQDSDGVTNREVKLEVISHPAGFTNPGDGTPVWFSNPMVLAKATALDYGSLLKLGVDFYDFEGDVLTITKTSGPDWLVLTQNSDDTWRLSGMPTAADAGENSFTFNVSDILSSDTEIKITV 6dns A 2.24 BS03 CA A 3 G419 D451 P452 E453 D502 D504 G389 D421 P422 E423 D472 D474 Q08I46 PDPNQGLRAEWMRGALGMLWLPERTFNGNIEGIRIDDFLTQIKDIRTVDYVQLPLTSPNIFSPTHVAPHPIIESLWQGDTDANGDPINLVAPRESVDDPLLSWLKALRAAGLRTEIYVNSYNLLARIPEDTQADYPDVSARWMEWCDTNTEAQAFINSQTYHEGNGRRKYMFCYAEFILKEYAQRYGDLIDAWCFDSADNVMEDECGDDPASEDVNDQRIYQAFADACHAGNPNAAIAFNNSVGDREGNPFTSATLFDDYTFGHPFGGAGNMVVPEALYTYNHDLVVFMQTNNGYAFRDDTRTWNDNVVAHFFPKQSTTSWNAGNTPCLTDEQFVEWTSTGIVNGGGITWGTPLVRTNLENAPVLTLQPYALNQFELTDTYLKEFQSPGKPNWSRQYTILPAIYPGQPYSHNLVEGVDFWDPEGVGITGLTASGTLPAWLTISQTATGTWTLSGTPPVSEASNYTFELMAQDSDGVTNREVKLEVISHPAGFTNPGDGTPVWFSNPMVLAKATALDYGSLLKLGVDFYDFEGDVLTITKTSGPDWLVLTQNSDDTWRLSGMPTAADAGENSFTFNVSDILSSDTEIKITV 6dnt A 1.66 BS01 NAD A 1 G10 L12 G13 F14 I15 D33 N34 L35 S36 S37 G38 E56 D57 L58 L76 A77 A78 A80 N95 S118 S119 S120 Y144 K148 Y171 F172 V174 G10 L12 G13 F14 I15 D33 N34 L35 S36 S37 G38 E56 D57 L58 L76 A77 A78 A80 N95 S118 S119 S120 Y144 K148 Y171 F172 V174 D3E402 30242905 MKDKNVVVTGGLGFIGSHIVDALIDDNKVTIIDNLSSGKMENLNNPNHENLTIIKEDLMDADLEKILKDKDYVFHLAALASVPGSVAEPLRYNQNNIDASLKLFIACKNNNIKKVIFSSSSAVYGENPNMPLKESENFLPCSPYAAQKASCELYLKSFHESYGLDYVALRYFNVFGPRQDENSPYAAVIPKFISAILNGESPVIYGDGEQSRDFIYVKEIAKANILSAESDYNGVINVALGKSMTINRLFEIISDVLESDIDVKYLDERPGDIKHSLADISNLDKISFKPDEDKFEEQLRETVKWFISQM 6dnt A 1.66 BS02 EPZ A 1 A80 S120 S121 Y144 F172 N173 Y185 A187 V188 K191 V203 I204 Y205 Q210 R212 I246 R269 D272 A80 S120 S121 Y144 F172 N173 Y185 A187 V188 K191 V203 I204 Y205 Q210 R212 I246 R269 D272 D3E402 30242905 MKDKNVVVTGGLGFIGSHIVDALIDDNKVTIIDNLSSGKMENLNNPNHENLTIIKEDLMDADLEKILKDKDYVFHLAALASVPGSVAEPLRYNQNNIDASLKLFIACKNNNIKKVIFSSSSAVYGENPNMPLKESENFLPCSPYAAQKASCELYLKSFHESYGLDYVALRYFNVFGPRQDENSPYAAVIPKFISAILNGESPVIYGDGEQSRDFIYVKEIAKANILSAESDYNGVINVALGKSMTINRLFEIISDVLESDIDVKYLDERPGDIKHSLADISNLDKISFKPDEDKFEEQLRETVKWFISQM 6dnt A 1.66 BS03 ZN A 1 E209 H275 E209 H275 D3E402 30242905 MKDKNVVVTGGLGFIGSHIVDALIDDNKVTIIDNLSSGKMENLNNPNHENLTIIKEDLMDADLEKILKDKDYVFHLAALASVPGSVAEPLRYNQNNIDASLKLFIACKNNNIKKVIFSSSSAVYGENPNMPLKESENFLPCSPYAAQKASCELYLKSFHESYGLDYVALRYFNVFGPRQDENSPYAAVIPKFISAILNGESPVIYGDGEQSRDFIYVKEIAKANILSAESDYNGVINVALGKSMTINRLFEIISDVLESDIDVKYLDERPGDIKHSLADISNLDKISFKPDEDKFEEQLRETVKWFISQM 6dnw A 2.85 BS01 NUC B 1 R135 M136 G139 K142 R143 T152 A153 K154 R156 T165 S189 T191 Y207 N208 M254 N259 N261 K262 K286 S290 K293 Y295 Y297 Y299 T308 K313 I318 R320 R2 M3 G6 K9 R10 T19 A20 K21 R23 T32 S56 T58 Y74 N75 M121 N126 N128 K129 K153 S157 K160 Y162 Y164 Y166 T175 K180 I185 R187 Q928V6 30227134 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYLEFREKQLYLKSLINKIYIDGEQVTIEWL 6dnw A 2.85 BS02 NUC C 1 D134 M136 K140 T151 R156 T206 R209 N212 W213 Y225 K226 P258 N259 K262 S264 A265 S266 N269 N270 V282 H283 R285 D287 T288 K303 K306 D1 M3 K7 T18 R23 T73 R76 N79 W80 Y92 K93 P125 N126 K129 S131 A132 S133 N136 N137 V149 H150 R152 D154 T155 K170 K173 Q928V6 30227134 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYLEFREKQLYLKSLINKIYIDGEQVTIEWL 6dnw A 2.85 BS03 ZN A 1 C274 C277 C302 C314 C141 C144 C169 C181 Q928V6 30227134 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYLEFREKQLYLKSLINKIYIDGEQVTIEWL 6dtj A 3.10 BS01 H9A A 1 G30 C31 S181 L182 V348 H377 G10 C11 S161 L162 V326 H355 2.3.1.43 P04180 HTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILLGAH 6dtj A 3.10 BS02 H94 A 1 M49 C50 Y51 F58 I60 D63 N65 M66 P69 G71 C74 W75 N78 M29 C30 Y31 F38 I40 D43 N45 M46 P49 G51 C54 W55 N58 2.3.1.43 P04180 HTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILLGAH 6dtj B 3.10 BS01 H9A B 1 G30 C31 S181 L182 H377 G10 C11 S161 L162 H350 2.3.1.43 P04180 HTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILL 6dvh A 1.70 BS01 FMN A 1 V45 A96 P97 I98 G99 V100 S128 Q150 Y152 T178 K266 S288 H290 G291 R293 D320 S321 G322 R324 G343 R344 V46 A97 P98 I99 G100 V101 S129 Q151 Y153 T179 K267 S289 H291 G292 R294 D321 S322 G323 R325 G344 R345 1.13.12.4 P21795 30207005 MSNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLRGLALTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dvh A 1.70 BS02 SO4 A 1 Y44 Y152 F184 R187 H290 R293 Y45 Y153 F185 R188 H291 R294 1.13.12.4 P21795 30207005 MSNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLRGLALTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dvh B 1.70 BS02 SO4 B 1 Y44 R187 H290 R293 Y45 R188 H291 R294 1.13.12.4 P21795 30207005 MSNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLRGLALTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dvi A 2.30 BS03 SO4 A 2 R70 D387 R390 R71 D388 R391 1.13.12.4 P21795 30207005 MSNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLRGLCLTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dvi B 2.30 BS01 FMN B 1 A96 P97 I98 G99 S128 Q150 Y152 T178 K266 H290 G291 R293 D320 S321 G322 R324 G343 R344 A97 P98 I99 G100 S129 Q151 Y153 T179 K267 H291 G292 R294 D321 S322 G323 R325 G344 R345 1.13.12.4 P21795 30207005 MSNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLRGLCLTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dvi B 2.30 BS02 SO4 B 1 Y44 Y152 R187 H290 R293 Y45 Y153 R188 H291 R294 1.13.12.4 P21795 30207005 MSNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLRGLCLTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dvi D 2.30 BS01 FMN D 1 A96 P97 I98 G99 V100 S128 Q150 Y152 T178 K266 Y286 S288 H290 G291 R293 D320 S321 G322 R324 G343 R344 A97 P98 I99 G100 V101 S129 Q151 Y153 T179 K211 Y231 S233 H235 G236 R238 D265 S266 G267 R269 G288 R289 1.13.12.4 P21795 30207005 MSNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDCLTNYVTDPVFQKKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dvi D 2.30 BS02 SO4 D 1 Y44 Y152 R187 H290 R293 Y45 Y153 R188 H235 R238 1.13.12.4 P21795 30207005 MSNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDCLTNYVTDPVFQKKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dvi D 2.30 BS03 SO4 D 2 H53 R56 E60 H54 R57 E61 1.13.12.4 P21795 30207005 MSNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDCLTNYVTDPVFQKKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dvi E 2.30 BS01 FMN E 1 V45 P97 I98 G99 V100 S128 Q150 Y152 T178 K266 H290 G291 R293 D320 S321 G322 R324 G343 R344 V45 P97 I98 G99 V100 S128 Q150 Y152 T178 K266 H290 G291 R293 D320 S321 G322 R324 G343 R344 1.13.12.4 P21795 30207005 SNWGDYENEIYGQGLVGVAPTLPMSYADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGKTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPAYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLRGLCLTNYVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKASGDTPVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELTIDALRPTR 6dwm A 2.85 BS01 HEM A 1 R106 S122 R135 L142 I198 D313 L314 A317 G318 T321 V322 F376 F381 V382 T385 I386 H388 Q411 I449 F450 G451 R455 K456 C457 I458 G459 I462 A463 R72 S88 R101 L108 I164 D271 L272 A275 G276 T279 V280 F334 F339 V340 T343 I344 H346 Q369 I407 F408 G409 R413 K414 C415 I416 G417 I420 A421 1.14.14.1 P04798 KGLKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6dwm A 2.85 BS02 HJJ A 1 I115 S116 S122 F123 N222 F224 F258 L312 D313 G316 A317 F319 D320 T321 V382 L496 T497 I81 S82 S88 F89 N188 F190 F224 L270 D271 G274 A275 F277 D278 T279 V340 L454 T455 1.14.14.1 P04798 KGLKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6dwm B 2.85 BS01 HEM B 1 R106 M121 S122 R135 I198 D313 L314 A317 G318 T321 V322 F376 F381 V382 T385 I386 H388 Q411 I449 F450 G451 R455 K456 C457 I458 G459 I462 A463 R70 M85 S86 R99 I162 D277 L278 A281 G282 T285 V286 F340 F345 V346 T349 I350 H352 Q375 I413 F414 G415 R419 K420 C421 I422 G423 I426 A427 1.14.14.1 P04798 LKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6dwm B 2.85 BS02 HJJ B 1 I115 S116 S122 F123 N222 F224 L254 N255 F258 L312 D313 G316 A317 F319 D320 T321 V382 I386 L496 I79 S80 S86 F87 N186 F188 L218 N219 F222 L276 D277 G280 A281 F283 D284 T285 V346 I350 L460 1.14.14.1 P04798 LKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6dwm D 2.85 BS02 HJJ D 1 I115 S116 S122 F123 N222 F224 N255 F258 L312 G316 A317 F319 D320 T321 V382 I386 T497 I77 S78 S84 F85 N184 F186 N217 F220 L264 G268 A269 F271 D272 T273 V334 I338 T449 1.14.14.1 P04798 NPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQELSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6dwn A 3.00 BS02 AQ4 A 1 I115 S122 F123 N222 F224 L254 N255 F258 D313 G316 A317 F319 D320 I386 I79 S86 F87 N186 F188 L218 N219 F222 D277 G280 A281 F283 D284 I350 1.14.14.1 P04798 LKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6dwn C 3.00 BS02 AQ4 C 1 I115 S122 F123 N222 F224 L254 N255 F258 D313 G316 A317 F319 L496 I78 S85 F86 N185 F187 L217 N218 F221 D263 G266 A267 F269 L446 1.14.14.1 P04798 KNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6dwn D 3.00 BS01 HEM D 1 R106 S122 R135 I198 D313 L314 A317 G318 T321 V322 F376 F381 V382 T385 I386 H388 Q411 I449 F450 G451 R455 K456 C457 I458 G459 I462 A463 R69 S85 R98 I161 D254 L255 A258 G259 T262 V263 F317 F322 V323 T326 I327 H329 Q352 I390 F391 G392 R396 K397 C398 I399 G400 I403 A404 1.14.14.1 P04798 KNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6dwn D 3.00 BS02 AQ4 D 1 I115 S122 F123 N222 F224 F258 D313 G316 A317 F319 I386 L496 I78 S85 F86 N175 F177 F211 D254 G257 A258 F260 I327 L437 1.14.14.1 P04798 KNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6dwv B 2.20 BS01 ZN B 1 H8 H10 H178 E284 H6 H8 H176 E282 4.2.1.83 G2IQQ5 30207699 MIIDCHGHYTVLPKAHDEWREQQKAAFKAGQPAPPYPEISDDEIRETIEANQLRLIKERGADMTIFSPRASAMAPHVGDQSVAVPWAQACNNLIARVVDLFPETFAGVCMLPQSPEADMTSSIAELERCVNELGFIGCNLNPDPGGGHFKHPPLTDRFWYPFYEKMVELDVPAMIHVSGSCNPAMHATGAYYLAADTIAFMQLLQGNLFADFPTLRFIIPHGGGAVPYHWGRFRGLADMLKQPSLDTLLMNNVFFDTCVYHQPGINLLADVIDNKNILFGSEMVGAVRGIDPTTGHYFDDTKRYIDALDISDQERHAIFEGNTRRVFPRLDAKLKARGL 6dxk A 3.05 BS01 HJ4 A 1 M560 G567 G568 Q570 M604 R611 F623 M639 C643 M646 Y735 C736 I761 M31 G38 G39 Q41 M75 R82 F94 M110 C114 M117 Y206 C207 I232 P04150 30091920 PTLVSALETIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMYLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNSQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ 6dxk B 3.05 BS01 HJ4 B 1 L563 N564 L566 G567 Q570 V571 M604 L608 R611 F623 M646 Y735 C736 T758 I761 L34 N35 L37 G38 Q41 V42 M75 L79 R82 F94 M117 Y206 C207 T229 I232 P04150 30091920 PTLVSALETIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMYLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNSQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 6dzp F 3.42 BS01 NUC B 1 N31 M33 Q34 Q70 K71 E73 V74 R95 T97 R99 N26 M28 Q29 Q65 K66 E68 V69 R90 T92 R94 A0QSG1 30038002 KALPRLKQRYREEIREALQQEFNYANVMQIPGVVKVVVNMGVGDAARDAKLINGAINDLALITGQKPEVRRARKSIAQFKLREGMPIGARVTLRGDRMWEFLDRLISIALPRIRDFRGLSPKQFDGTGNYTFGLNEQSMFHEIDVDSIDRPRGMDITVVTTATNDAEGRALLRALGFPFKEN 6dzp P 3.42 BS01 NUC B 1 N9 I10 S11 E12 R14 R15 R18 H22 R26 R37 N41 R42 S43 A44 R45 H46 Q50 G57 A62 E67 R71 K77 K78 T108 G111 R112 N8 I9 S10 E11 R13 R14 R17 H21 R25 R36 N40 R41 S42 A43 R44 H45 Q49 G56 A61 E66 R70 K76 K77 T107 G110 R111 I7FGD9 30038002 AHKPVGQNISEVRRNARLRRHARLRKKVAGTAEVPRLVVNRSARHIHVQLVNDLNGTTLAAASSIEADVRAIDGDKKAHSVRVGQLIAERAKAAGVETVVFDRGGYTYGGRIAALADAAREAGLKF 6dzp W 3.42 BS01 NUC B 1 T19 G20 K21 G22 R25 R28 R29 V36 Y38 G39 H46 K81 Q93 H94 T16 G17 K18 G19 R22 R25 R26 V33 Y35 G36 H43 K78 Q90 H91 A0R3D2 30038002 TANIPNKLTANVRTRTGKGASRQARRDGKVPAVLYGHGTDPQHLELNARDFAAVLRSHGTNAILTLDIEGTEQLALTKALDVHPIRRNIQHADLLVVQRGEKVTVEVTVLVEGDATPGTLVTQDANTIEIEAEALSIPEQLTVSVEGVEAGTQITAGQISLPEGVNLISDPELLVVNVVEAPSAEALEEEGA 6dzp X 3.42 BS01 NUC B 1 G70 A71 K72 G74 G63 A64 K65 G67 A0R150 30038002 SSSRNGRDSAAQRLGVKRFGGQVVKAGEILVRQRGTHFHPGVNVGRGGDDTLFALAPGAVEFGAKRGRKTVNIVPVARP 6dzp g 3.42 BS01 NUC B 1 M1 K2 H6 M1 K2 H6 A0R554 30038002 MKPGIHPDYHPVVFQDAATGAQFLTRSTATSTRTIEWPTPSGPKTYPLIVVDVTSDSHPFWTGS 6e9e A 3.40 BS01 NUC B 1 K59 S60 M61 K63 K68 V132 D134 R138 R139 F140 N141 G142 R143 D155 M156 I178 Q179 E334 N342 N343 G379 F380 S381 K384 S402 N405 K406 Q409 R435 K443 Y447 K475 K517 N520 T524 N528 N532 F536 K574 S575 N581 A582 R584 Y587 I615 N627 R630 N631 A634 D639 P673 Q676 Y680 Q720 N723 K734 T746 K753 R761 Y823 V929 R930 K932 N933 L934 L939 F940 D941 K942 N943 G946 K2 S3 M4 K6 K11 V75 D77 R81 R82 F83 N84 G85 R86 D95 M96 I118 Q119 E260 N268 N269 G305 F306 S307 K310 S328 N331 K332 Q335 R361 K369 Y373 K401 K443 N446 T450 N454 N458 F462 K500 S501 N507 A508 R510 Y513 I541 N545 R548 N549 A552 D557 P591 Q594 Y598 Q633 N636 K647 T659 K666 R674 Y736 V842 R843 K845 N846 L847 L852 F853 D854 K855 N856 G859 B0MS50 30241607 TKSMAKAAGVKSVFAVGNTVYMTSFGRGNDAVLEQKIVDTSHEPLNIDDPAYQLNVVTMNGYSVTGHRGETVSAVTDNPLRRFNGRKPEQSVPTDMLCLKPTLEKKFFGKEFDDNIHIQLIYNILDIEKILAVYSTNAIYALNNMDFFMKRTTDETFDDFEKKKESTNSREKADFDAFEKFIGNYRLAYFADAFYVNKKAKNVLREDKELYSVLTLIGKLRHWCVHSEEGRAEFWLYKLDELKDDFKNVLDVVYNRPVEEINNRFIENNKVNIQILGSVYKNTDIAELVRSYYEFLITKKYKNMGFSIKKLRESMLEGKGYADKEYDSVRNKLYQMTDFILYTGYINEDSDRADDLVNTLRSSLKEDDKTTVYCKEADYLWKKYRESIREVADALDGDNIKKLSKSNIEIQEDKLRKCFISYADSVSEFTKLIYLLTRFLSGKEINDLVTTLINKFDNIRSFLEIMDELGLDRTFTAEYSFFEGSTKYLAELVELNSFVKSCSFDINAKRTMYRDALDILGIESDKTEEDIEKMIDNILQIKKNNGLRNFIASNVIDSNRFKYLVRYGNPKKIRETAKCKPAVRFVLNEIPDAQIERYYEACCPCSANKRREKLADMIAEIKFENFSDAGNYQKANVTSRTSEAEIKRKNQAIIRLYLTVMYIMLKNLVNVNARYVIAFHCVERDTKLYAESGLEVGNIEKNKTNLTMAVMGVKLENGIIKTEFDKSFAENAANRYLRNARWYKLILDNLKKSERAVVNEFRNTVCHLNAIRNININIKEIKEVENYFALYHYLIQKHLENRFADKKVERDTGDFISKLEEHKTYCKDFVKAYCTPFGYNLVRYKNLTIDGLFDKNYPGKDDS 6e9f A 3.30 BS01 NUC B 1 S60 M61 A62 K63 K68 S69 N117 V132 D134 R138 R139 F140 N141 G142 R143 D155 M156 N175 I178 Q179 Y182 D186 K189 K373 K376 N377 G379 S381 K398 D401 L434 S437 K443 Y447 G516 N520 N532 F536 L623 N626 N627 G628 N631 S635 R642 Y645 A675 Q676 R679 R742 R761 Y823 N826 V929 R930 K932 N933 L934 L939 K942 G946 K947 S3 M4 A5 K6 K11 S12 N60 V75 D77 R81 R82 F83 N84 G85 R86 D95 M96 N115 I118 Q119 Y122 D126 K129 K308 K311 N312 G314 S316 K333 D336 L369 S372 K378 Y382 G451 N455 N467 F471 L554 N557 N558 G559 N562 S566 R573 Y576 A606 Q607 R610 R656 R675 Y737 N740 V843 R844 K846 N847 L848 L853 K856 G860 K861 B0MS50 30241607 TKSMAKAAGVKSVFAVGNTVYMTSFGRGNDAVLEQKIVDTSHEPLNIDDPAYQLNVVTMNGYSVTGHRGETVSAVTDNPLRRFNGRKPEQSVPTDMLCLKPTLEKKFFGKEFDDNIHIQLIYNILDIEKILAVYSTNAIYALNNMSADENIENSDFFMKRTTDETFDDFEKKKESTNSREKADFDAFEKFIGNYRLAYFADAFYVNKKAKNVLREDKELYSVLTLIGKLAHWCVASEEGRAEFWLYKLDELKDDFKNVLDVVYNRPVEEINNRFIENNKVNIQILGSVYKNTDIAELVRSYYEFLITKKYKNMGFSIKKLRESMLEGKGYADKEYDSVRNKLYQMTDFILYTGYINEDSDRADDLVNTLRSSLKEDDKTTVYCKEADYLWKKYRESIREVADALDGDNIKKLSKSNIEIQEDKLRKCFISYADSVSEFTKLIYLLTRFLSGKEINDLVTTLINKFDNIRSFLEIMDELGLDRTFTAEYSFFEGSTKYLAELVELNSFVKSCSFDINAKRTMYRDALDILGIESDKTEEDIEKMIDNILQIDKKLKKNNGLRNFIASNVIDSNRFKYLVRYGNPKKIRETAKCKPAVRFVLNEIPDAQIERYYEACCPCSANKRREKLADMIAEIKFENFSRTSEAEIKRKNQAIIRLYLTVMYIMLKNLVNVNARYVIAFHCVERDTKLYAESGLEVGNIEKNKTNLTMAVMGVKLENGIIKTEFDKSFAENAANRYLRNARWYKLILDNLKKSERAVVNEFANTVCALNAIRNININIKEIKEVENYFALYHYLIQKHLENRFADKKVERDTGDFISKLEEHKTYCKDFVKAYCTPFGYNLVRYKNLTIDGLFDKNYPGKDDS 6e9f A 3.30 BS02 NUC C 1 N86 G126 N377 K383 R386 Y408 R435 N520 D521 T524 I527 N528 F632 N636 D639 S640 N641 R679 Y680 A683 R735 R742 N29 G69 N312 K318 R321 Y343 R370 N455 D456 T459 I462 N463 F563 N567 D570 S571 N572 R610 Y611 A614 R649 R656 B0MS50 30241607 TKSMAKAAGVKSVFAVGNTVYMTSFGRGNDAVLEQKIVDTSHEPLNIDDPAYQLNVVTMNGYSVTGHRGETVSAVTDNPLRRFNGRKPEQSVPTDMLCLKPTLEKKFFGKEFDDNIHIQLIYNILDIEKILAVYSTNAIYALNNMSADENIENSDFFMKRTTDETFDDFEKKKESTNSREKADFDAFEKFIGNYRLAYFADAFYVNKKAKNVLREDKELYSVLTLIGKLAHWCVASEEGRAEFWLYKLDELKDDFKNVLDVVYNRPVEEINNRFIENNKVNIQILGSVYKNTDIAELVRSYYEFLITKKYKNMGFSIKKLRESMLEGKGYADKEYDSVRNKLYQMTDFILYTGYINEDSDRADDLVNTLRSSLKEDDKTTVYCKEADYLWKKYRESIREVADALDGDNIKKLSKSNIEIQEDKLRKCFISYADSVSEFTKLIYLLTRFLSGKEINDLVTTLINKFDNIRSFLEIMDELGLDRTFTAEYSFFEGSTKYLAELVELNSFVKSCSFDINAKRTMYRDALDILGIESDKTEEDIEKMIDNILQIDKKLKKNNGLRNFIASNVIDSNRFKYLVRYGNPKKIRETAKCKPAVRFVLNEIPDAQIERYYEACCPCSANKRREKLADMIAEIKFENFSRTSEAEIKRKNQAIIRLYLTVMYIMLKNLVNVNARYVIAFHCVERDTKLYAESGLEVGNIEKNKTNLTMAVMGVKLENGIIKTEFDKSFAENAANRYLRNARWYKLILDNLKKSERAVVNEFANTVCALNAIRNININIKEIKEVENYFALYHYLIQKHLENRFADKKVERDTGDFISKLEEHKTYCKDFVKAYCTPFGYNLVRYKNLTIDGLFDKNYPGKDDS 6eac A 2.27 BS01 MG A 1 N253 D262 N254 D263 2.7.7.- Q87VB1 SMKALDELVFDNRFARLGDAFSTHVLPEPIDAPRLVVASESALALLDLAPEQSELPLFAEIFSGHKLWAEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRAACVVSSNTPVWREKQEYAAMVLRLAQSHVRFGSLEYLFYTKQPEHLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALGQALTPFVSVEALRETIGLFLPLYQAHYLDLMRRRLGLTVAQDQDDKLVSQLLQLMQNSGVDYTLFFRRLGDQPAAQALRALRDDFVDIKVFDDWAQAYQARIAAEENGTEQARKERMHAVNPLYILRNYLAQNAIEAAEKGDYEEVRRLHQVLCTPFTEQPGMEGYAQRPP 6eac A 2.27 BS02 CA A 1 R93 D262 R94 D263 2.7.7.- Q87VB1 SMKALDELVFDNRFARLGDAFSTHVLPEPIDAPRLVVASESALALLDLAPEQSELPLFAEIFSGHKLWAEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRAACVVSSNTPVWREKQEYAAMVLRLAQSHVRFGSLEYLFYTKQPEHLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALGQALTPFVSVEALRETIGLFLPLYQAHYLDLMRRRLGLTVAQDQDDKLVSQLLQLMQNSGVDYTLFFRRLGDQPAAQALRALRDDFVDIKVFDDWAQAYQARIAAEENGTEQARKERMHAVNPLYILRNYLAQNAIEAAEKGDYEEVRRLHQVLCTPFTEQPGMEGYAQRPP 6eac A 2.27 BS03 CA A 2 S362 G363 D388 S363 G364 D389 2.7.7.- Q87VB1 SMKALDELVFDNRFARLGDAFSTHVLPEPIDAPRLVVASESALALLDLAPEQSELPLFAEIFSGHKLWAEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRAACVVSSNTPVWREKQEYAAMVLRLAQSHVRFGSLEYLFYTKQPEHLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALGQALTPFVSVEALRETIGLFLPLYQAHYLDLMRRRLGLTVAQDQDDKLVSQLLQLMQNSGVDYTLFFRRLGDQPAAQALRALRDDFVDIKVFDDWAQAYQARIAAEENGTEQARKERMHAVNPLYILRNYLAQNAIEAAEKGDYEEVRRLHQVLCTPFTEQPGMEGYAQRPP 6eac A 2.27 BS04 CA A 3 Q357 L358 N361 Q358 L359 N362 2.7.7.- Q87VB1 SMKALDELVFDNRFARLGDAFSTHVLPEPIDAPRLVVASESALALLDLAPEQSELPLFAEIFSGHKLWAEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRAACVVSSNTPVWREKQEYAAMVLRLAQSHVRFGSLEYLFYTKQPEHLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALGQALTPFVSVEALRETIGLFLPLYQAHYLDLMRRRLGLTVAQDQDDKLVSQLLQLMQNSGVDYTLFFRRLGDQPAAQALRALRDDFVDIKVFDDWAQAYQARIAAEENGTEQARKERMHAVNPLYILRNYLAQNAIEAAEKGDYEEVRRLHQVLCTPFTEQPGMEGYAQRPP 6eac A 2.27 BS05 ANP A 1 Y77 L89 G90 D91 G92 R93 K113 S121 R122 G124 D125 G126 R127 R165 R176 R183 N253 D262 Y78 L90 G91 D92 G93 R94 K114 S122 R123 G125 D126 G127 R128 R166 R177 R184 N254 D263 2.7.7.- Q87VB1 SMKALDELVFDNRFARLGDAFSTHVLPEPIDAPRLVVASESALALLDLAPEQSELPLFAEIFSGHKLWAEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRAACVVSSNTPVWREKQEYAAMVLRLAQSHVRFGSLEYLFYTKQPEHLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALGQALTPFVSVEALRETIGLFLPLYQAHYLDLMRRRLGLTVAQDQDDKLVSQLLQLMQNSGVDYTLFFRRLGDQPAAQALRALRDDFVDIKVFDDWAQAYQARIAAEENGTEQARKERMHAVNPLYILRNYLAQNAIEAAEKGDYEEVRRLHQVLCTPFTEQPGMEGYAQRPP 6eac B 2.27 BS04 CA B 3 E410 G412 E411 G413 2.7.7.- Q87VB1 SMKALDELVFDNRFARLGDAFSTHVLPEPIDAPRLVVASESALALLDLAPEQSELPLFAEIFSGHKLWAEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRAACVVSSNTPVWREKQEYAAMVLRLAQSHVRFGSLEYLFYTKQPEHLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALGQALTPFVSVEALRETIGLFLPLYQAHYLDLMRRRLGLTVAQDQDDKLVSQLLQLMQNSGVDYTLFFRRLGDQPAAQALRALRDDFVDIKVFDDWAQAYQARIAAEENGTEQARKERMHAVNPLYILRNYLAQNAIEAAEKGDYEEVRRLHQVLCTPFTEQPGMEGYAQRPP 6eac B 2.27 BS05 CA B 4 A68 A70 A69 A71 2.7.7.- Q87VB1 SMKALDELVFDNRFARLGDAFSTHVLPEPIDAPRLVVASESALALLDLAPEQSELPLFAEIFSGHKLWAEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRAACVVSSNTPVWREKQEYAAMVLRLAQSHVRFGSLEYLFYTKQPEHLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALGQALTPFVSVEALRETIGLFLPLYQAHYLDLMRRRLGLTVAQDQDDKLVSQLLQLMQNSGVDYTLFFRRLGDQPAAQALRALRDDFVDIKVFDDWAQAYQARIAAEENGTEQARKERMHAVNPLYILRNYLAQNAIEAAEKGDYEEVRRLHQVLCTPFTEQPGMEGYAQRPP 6eac D 2.27 BS04 CA D 3 M1 D46 M1 D46 2.7.7.- Q87VB1 MKALDELVFDNRFARLGDAFSTHVLPEPIDAPRLVVASESALALLDLAPEQSELPLFAEIFSGHKLWAEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRAACVVSSNTPVWREKQEYAAMVLRLAQSHVRFGSLEYLFYTKQPEHLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALGQALTPFVSVEALRETIGLFLPLYQAHYLDLMRRRLGLTVAQDQDDKLVSQLLQLMQNSGVDYTLFFRRLGDQPAAQALRALRDDFVDIKVFDDWAQAYQARIAAEENGTEQARKERMHAVNPLYILRNYLAQNAIEAAEKGDYEEVRRLHQVLCTPFTEQPGMEGYAQRPP 6eum A 1.18 BS03 BY5 A 1 W89 H116 H118 D120 H179 C198 N210 H240 W54 H81 H83 D85 H144 C163 N175 H205 3.5.2.6 P04190 29655609 KTVIKNETGTISISQLNKNVWVHTELGSFNGEAVPSNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDVIITHAHADRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMKVETFYPGKGHTEDNIVVWLPQYNILVGGCLVKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHGEVGDKGLLLHTLDLLK 6ew3 A 2.14 BS03 S3C A 1 W87 H114 H116 D117 D118 H179 C198 N210 H240 W56 H83 H85 D86 D87 H148 C167 N179 H209 D1MEN9 29655609 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 6ewe A 1.46 BS03 C0W A 1 H116 H118 D120 H179 C198 N210 D213 H240 H77 H79 D81 H140 C159 N171 D174 H201 3.5.2.6 P04190 29655609 KTVIKNETGTISISQLNKNVWVHTELGSAVPSNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDVIITHAHADRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMKVETFYPGKGHTEDNIVVWLPQYNILVGGCLVKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHGEVGDKGLLLHTLDLLK 6ey1 A 1.20 BS01 MN A 1 H209 D211 H270 H125 D127 H186 I6QVT6 CDKLALEKTWQLQKNERLSNMVVNQLNTNGFCIINNFLGSSCSTEVLQQVLNLYQSGVFSNGIRGDKIAWIGGDERGCEAIKYLSSCVDSLISRCNGRLGNYMITGRTKCMVACYPGSGLGYIRHIDNPNRDGRCVTVLYYLNPNWNSQDCGGQLWLYPNNENKVVKIDPIFDRLLLFWSDRRNPHEVKPAYAMRYAITLWYFDEKERALS 6ey7 A 2.90 BS04 C3W A 1 D463 F466 S473 E534 N536 M579 G580 D651 D35 F38 S43 E104 N106 M149 G150 D202 P16732 LITDQSREEFDILRYSTLNTNAYDYFGKTLYVYLDPAFTRKASGTGVAAVGAYRHQFLIYGLEHFFLRDLSESSEVAIAECAAHMIISVLSLHPYLDELRIAVEGNTNQAAAVRIACLIRQSVQSSTLIRVLFYHTPDQNHIEQPFYLMGRDKALAVEQFISRFNSGYIKASQELVSYTIKLSHDPIEYLLEQIQNLHRSDDLIIAVIMATYLCDDIHAIRFRVS 6ey7 B 2.90 BS03 C3W B 1 D463 S473 E534 N536 T537 M579 D651 D36 S43 E102 N104 T105 M147 D204 P16732 VLITDQSREEFDILRYSTLNTNAYDYFGKTLYVYLDPAFTKASGTGVAAVGAYRHQFLIYGLEHFFLRSESSEVAIAECAAHMIISVLSLHPYLDELRIAVEGNTNQAAAVRIACLIRQSVQSSTLIRVLFYHTPDQNHIEQPFYLMGRDKALAVEQFISRFNSGYIKASQELVSYTIKLSHDPIEYLLEQIQNLHRVTRISDDLIIAVIMATYLCDDIHAIRFRVS 6ey7 C 2.90 BS03 C3W C 1 D463 F466 S473 E534 N536 T537 D651 D35 F38 S41 E100 N102 T103 D198 P16732 LITDQSREEFDILRYSTLNTNAYDYFGKTLYVYLDPAFTASGTGVAAVGAYRHQFLIYGLEHFFLRDESSEVAIAECAAHMIISVLSLHPYLDELRIAVEGNTNQAAAVRIACLIRQSVQSSTLIRVLFYHTPDQNHIEQPFYLMGRDKALAVEQFISRFNSGYIKASQELVSYTIKLSHDPIEYLLEQIQNLRISDDLIIAVIMATYLCDDIHAIRFRVS 6ey7 D 2.90 BS03 C3W D 1 D463 S473 E534 N536 M579 G580 D651 D35 S38 E95 N97 M140 G141 D191 P16732 LITDQSREEFDILRYSTLNTNAYDYFGKTLYVYLDPASGTGVAAVGAYRHQFLIYGLEHFFLESSEVAIAECAAHMIISVLSLHPYLDELRIAVEGNTNQAAAVRIACLIRQSVQSSTLIRVLFYHTPDQNHIEQPFYLMGRDKALAVEQFISRFNSGYIKASQELVSYTIKLSHDPIEYLLEQIQNLSDDLIIAVIMATYLCDDIHAIRFRVS 6f0w A 1.30 BS01 III S 1 Q137 L138 A139 N141 I147 R148 W154 D173 T189 G190 R191 T192 Y206 R208 H209 I210 D211 P213 N214 R218 R266 W285 Y286 F287 R292 S295 S296 Q61 L62 A63 N65 I71 R72 W78 D97 T113 G114 R115 T116 Y130 R132 H133 I134 D135 P137 N138 R142 R189 W208 Y209 F210 R215 S218 S219 I6QVT6 CDKTEKTWQLQKNERLSNMVVNQLNTNGFCIINNFLGSSCSTEVLQQVLNLYQSGVFSNGQLARNVSVNRIRGDKIAWIGGDERGCEAIKYLSSCVDSLISRCNGRLGNYMITGRTKCMVACYPGSGLGYIRHIDNPNRDGRCVTVLYYLNPNWNSQDCGGQLWLYPNENKVVKIDPIFDRLLLFWSDRRNPHEVKPAYAMRYAITLWYFDEKERALSSQ 6f2f A 1.65 BS01 7MT A 1 A8 N9 F35 E36 I40 R75 A8 N9 F35 E36 I40 R75 3.5.1.124,3.4.22.- O59413 29806881 MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERGTITGKHGYSVKVDLTFDKVNPEEFDALVLPGGRAPERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVLRGRKGTSYPGIKDDMINAGVEWVDAEVVVDGNWVSSRVPADLYAWMREFVKLLK 6f2f C 1.65 BS02 2HA C 1 I128 G131 V132 E133 I128 G131 V132 E133 3.5.1.124,3.4.22.- O59413 29806881 MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERGTITGKHGYSVKVDLTFDKVNPEEFDALVLPGGRAPERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVLRGRKGTSYPGIKDDMINAGVEWVDAEVVVDGNWVSSRVPADLYAWMREFVKLLK 6f2h B 2.19 BS01 7MT B 1 A8 N9 F35 E36 R75 A8 N9 F35 E36 R75 3.5.1.124,3.4.22.- O59413 29806881 MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERGTITGKHGYSVKVDLTFDKVNPEEFDALVLPGGRAPERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVLRGRKGTSYPGIKDDMINAGVEWVDAEVVVDGNWVSSRVPADLYAWMREFVKLLK 6f2h E 2.19 BS01 7MT E 1 A8 N9 S34 F35 E36 I40 R75 A8 N9 S34 F35 E36 I40 R75 3.5.1.124,3.4.22.- O59413 29806881 MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERGTITGKHGYSVKVDLTFDKVNPEEFDALVLPGGRAPERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVLRGRKGTSYPGIKDDMINAGVEWVDAEVVVDGNWVSSRVPADLYAWMREFVKLLK 6f2m A 1.80 BS01 7MT A 1 P13 G14 F17 E18 P55 P13 G14 F17 E18 P37 Q6QGE8 29806881 MRLPDPYTNPEYPGLGFESVNLVDNDAQYWGINISYPELFPDEYAFLDSRLLEYKRTGDYLDVLLPQYEAFRVRGDTKSVTIPAGQKGSQIILNTNGTLTGQPKAGDLFKLSTHPKVYKITNFSSSGNVWNISLYPDLFITTTGSEKPVFNGILFRTKLMNGDSFGSTLNNNGTYSGISLSLRES 6f2m D 1.80 BS01 7MT D 1 R68 E71 R74 T75 R50 E53 R56 T57 Q6QGE8 29806881 MRLPDPYTNPEYPGLGFESVNLVDNDAQYWGINISYPELFPDEYAFLDSRLLEYKRTGDYLDVLLPQYEAFRVRGDTKSVTIPAGQKGSQIILNTNGTLTGQPKAGDLFKLSTHPKVYKITNFSSSGNVWNISLYPDLFITTTGSEKPVFNGILFRTKLMNGDSFGSTLNNNGTYSGISLSLRES 6f2n A 1.15 BS03 CF8 A 1 V69 W89 H116 H118 D120 H179 C198 K201 N210 H240 V31 W51 H78 H80 D82 H141 C160 K163 N172 H202 3.5.2.6 P04190 29655609 EKTVIKNETGTISISQLNKNVWVHTELGSAVPSNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDVIITHAHADRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMKVETFYPGKGHTEDNIVVWLPQYNILVGGCLVKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHGEVGDKGLLLHTLDLLK 6f55 A BS01 III B 1 L11 Y12 Q17 E18 D37 Q39 W41 L53 P55 N57 Y58 L11 Y12 Q17 E18 D37 Q39 W41 L53 P55 N57 Y58 Q1G1I6 30244966 MKVPGVRVRALYDYTGQEADELSFKAGEELMKISEEDEQGWCKGRLLTGHVGLYPANYVEKVGLAAA 6frn A 1.74 BS01 FMN A 1 T266 M267 H268 G269 S270 T271 P317 T318 I319 Y320 D321 S353 M354 G355 G356 N357 G358 Y383 T260 M261 H262 G263 S264 T265 P311 T312 I313 Y314 D315 S347 M348 G349 G350 N351 G352 Y377 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEPDSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6frn A 1.74 BS02 TB A 1 E86 D88 H89 D171 H234 E86 D88 H89 D165 H228 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEPDSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6frn A 1.74 BS03 FMN D 1 H26 E86 L203 H26 E86 L197 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEPDSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6frn B 1.74 BS02 TB B 1 D88 H89 D171 H234 D88 H89 D165 H228 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEADSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6frn C 1.74 BS01 FMN B 1 H26 E86 W153 L203 H26 E86 W153 L203 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEAPLLHWPDSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6frn C 1.74 BS04 7MT C 1 R73 E74 R73 E74 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEAPLLHWPDSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6frn C 1.74 BS05 7MT C 2 G72 R73 E74 G72 R73 E74 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEAPLLHWPDSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6frn D 1.74 BS01 FMN A 1 H26 W153 L203 H26 W153 L203 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEAPLLHWPDSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6frn D 1.74 BS03 CA D 1 K362 E378 K362 E378 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEAPLLHWPDSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6frn D 1.74 BS05 7MT D 1 R73 E74 K76 R73 E74 K76 29806881 MKADAVKIADGVYWVGVLDWDIRMYHGYTLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKGAPFKVVKSLESIDLGGKTLTFLEAPLLHWPDSMFTLYAEEGILFSNDAFGQHLCFTQRFDHEIPENILMDANQKFYANLITPLSKLVLKKFKEVIELGLLEKIKMIAPSHGQIWTDPMKVIGAYQDFATGKCKDKVTIVYDTMHGSTQKMAHAFAEGIMSEGVDVKMYFLHNDERSEIVKDILDSKAFLLGAPTIYDEPFPSVGDLIYYLKGLKFNRTGLKRLALAFGSMGGNGGGTKVLAEKLKECGFEVLDEYELYYVPTEDELEKCYNMGKRLAVKVKEMKT 6fro A 1.42 BS01 7MT A 1 W62 W63 L75 D101 G102 N103 W62 W63 L75 D101 G102 N103 3.2.1.17 P00698 29806881 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 6fuf A 3.12 BS01 RET A 1 A117 T118 E122 I189 M207 H211 W265 K296 A116 T117 E121 I188 M206 H210 W264 K295 P02699 CGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIYVIAFLICWLPYAGVAFYIFTHQGSCFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCM 6g63 A 3.95 BS01 NUC B 1 K433 E434 R488 K417 E418 R472 3.1.26.12 P21513 RMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEEAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPAGGISRRIEGDDRTELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIRINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIRFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAM 6g63 G 3.95 BS01 NUC B 1 M1 R3 Q22 H268 Y269 Q270 M1 R3 Q22 H251 Y252 Q253 3.1.26.12 P21513 MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEEAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRGDDRTELKEALASLGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIRINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIRFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAM 6g63 N 3.95 BS02 U N 1 V128 S140 R142 I167 R169 T170 R223 R371 V121 S133 R135 I154 R156 T157 R210 R355 3.1.26.12 P21513 MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIRINSARATDIEETAFNTNLEAADEIARQLRLRDLGGLIVIRFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAM 6gp8 A 1.75 BS01 APC A 1 N51 A55 D93 M98 N106 L107 G135 V136 G137 F138 T184 N57 A61 D99 M104 N112 L113 G141 V142 G143 F144 T190 P07900 30248409 VPRGSHMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAASGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKER 6gpo A 1.48 BS01 CMP A 1 N51 A55 D93 M98 N106 L107 T184 N58 A62 D100 M105 N113 L114 T191 P07900 30248409 LVPRGSHMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAASGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKER 6gpr A 2.35 BS01 CMP A 1 N51 A55 D93 I96 M98 L107 T184 N41 A45 D83 I86 M88 L97 T174 P07900 30248409 PMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 6gqu A 1.72 BS01 CMP A 1 N51 A55 D93 M98 N106 L107 R112 T184 N57 A61 D99 M104 N112 L113 R118 T190 P07900 30248409 VPRGSHMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKER 6ha9 A 2.00 BS01 NFG A 1 A255 V296 D298 K301 H323 Y325 A160 V201 D203 K206 H228 Y230 3.2.1.4 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNAPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGA 6ha9 A 2.00 BS02 BGC A 1 H208 N254 Y325 E390 W432 H113 N159 Y230 E295 W337 3.2.1.4 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNAPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGA 6haa A 1.70 BS01 G2F A 1 H208 N254 E390 W432 H113 N159 E295 W337 3.2.1.4 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNAPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGA 6haa B 1.70 BS04 XYS B 1 N434 G436 D438 S441 N339 G341 D343 S346 3.2.1.4 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNAPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGA 6hjj A 2.13 BS01 G7T A 1 L139 G140 V147 A160 K162 L169 V174 Q177 L178 E181 L194 C210 E211 A213 T217 L263 A273 F275 L13 G14 V21 A34 K36 L43 V48 Q51 L52 E55 L68 C84 E85 A87 T91 L137 A147 F149 2.7.11.1 O14965 30239186 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLICEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNA 6hjk A 2.40 BS01 G7W A 1 L139 F144 V147 K162 V174 Q177 L178 L194 E211 Y212 A213 L263 F275 G276 W277 V279 L13 F18 V21 K36 V48 Q51 L52 L68 E85 Y86 A87 L137 F149 G150 W151 V153 2.7.11.1 O14965 30239186 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLICEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 6hpg A 2.00 BS01 III a 1 K492 N496 Y499 Y511 T523 N527 A530 V556 K557 L560 R561 T564 E586 N589 T591 K10 N14 Y17 Y29 T41 N45 A48 V74 K75 L78 R79 T82 E104 N107 T109 F4KCL7 29374544 GNMEASEVMKEKGNAAYKGKQWNKAVNFYTEAIKLNGANATYYCNRAAAFLELCCFQQAEQDCTKAMLIDKKNVKAYLRRGTARESLVRYKEAAADFRHALVLEPQNKTAKVAEKRLRKHI 6hpg B 2.00 BS01 III b 1 K492 N496 Y499 Y511 T523 N527 K557 L560 R561 T564 E586 N589 K10 N14 Y17 Y29 T41 N45 K75 L78 R79 T82 E104 N107 F4KCL7 29374544 GNMEASEVMKEKGNAAYKGKQWNKAVNFYTEAIKLNGANATYYCNRAAAFLELCCFQQAEQDCTKAMLIDKKNVKAYLRRGTARESLVRYKEAAADFRHALVLEPQNKTAKVAEKRL 6hpg F 2.00 BS01 III f 1 K492 N496 Y499 Y511 N527 A530 V556 K557 L560 R561 T564 E586 N589 K10 N14 Y17 Y29 N45 A48 V74 K75 L78 R79 T82 E104 N107 F4KCL7 29374544 GNMEASEVMKEKGNAAYKGKQWNKAVNFYTEAIKLNGANATYYCNRAAAFLELCCFQQAEQDCTKAMLIDKKNVKAYLRRGTARESLVRYKEAAADFRHALVLEPQNKTAKVAEKRL 6if8 A 2.00 BS01 ADE A 1 A77 G78 Q151 F152 M153 V172 E173 M174 S197 D198 Q204 F208 A83 G84 Q148 F149 M150 V169 E170 M171 S194 D195 Q201 F205 3.2.2.9 A0KIZ1 AMDPEFMKVGIIGAMEQEVALLRSQMSNPTTLQLGGCEFYQGTLAGKEVILTRSGIGKVAASVATSLLLEKFAPDCVINTGSAGGFAQDLHIGDVVIASEMRFHDVDVTAFGYEMGQMAQQPAAFPCDETLIAVAQDCKVGLICTGDQFMCKPDAIAKARADFPQMLAVEMEGAAIGQVCHMFKVPYLVVRAMSDIAGKEQVESFDAFIEVAGKHSAEVIIKMLGKL 6m8n A 1.55 BS01 CA A 1 Y258 K259 T278 R282 Y223 K224 T243 R247 GIEYNASWMAGTWGITQRVDGGYKLDNSADSSNWQAGAEEIVTNIPAAEYVITSFTHPAHGHLFTLRTNNNVDVSAIHPDMVPTLENEKIILDVINIYRAAGKKVILYLNSAGPSMAEERGDTDIQAAWDEYYINEWDGDEAAAWRNLARGYVERFDGLVDGYWLDNSRNLPGEVSDFVAMLRSVDPELTIAVNYDQHYFTDDNGEYLYVDSDGLDDEDESDYKIVKHVVTNEYMDFTNGHVTPLGRGAPPNSWAYEEYTIPDMIEVPWETYDGSKYALKHGWFPIRNSWSGSKAELMFDVEQAYRFVRTVTDGGAAMTWSTTQDNGYMTADEMSIMIEISNRMTQTPKPDYSVYERPKGAYLVSEI 6mfe A 1.44 BS02 S73 A 1 P16 H37 M38 F39 I42 F43 D91 L92 V127 V128 I140 D144 L147 F153 Y154 T157 M233 L236 P18 H39 M40 F41 I44 F45 D93 L94 V129 V130 I142 D146 L149 F155 Y156 T159 M235 L238 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTPPPLTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDLI 6mgz B 1.65 BS04 MG B 1 D95 D130 D54 D89 A0A0G2ST15 GDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKL 6mij A 1.96 BS01 GDP A 1 D22 H23 G24 K25 T26 T27 Y47 N136 K137 D139 L140 S174 A175 L176 D14 H15 G16 K17 T18 T19 Y39 N128 K129 D131 L132 S166 A167 L168 N9JNN0 NKPHVNVGTIGHVDHGKTTLTAAIATICAKTYGGEAKDYSQIDSAPEEKARGITINTSHVEYDSPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGPMPQTREHILLSRQVGVPYIIVFLNKCDLVDDEELLELVEMEVRELLSTYDFPGDDTPVIRGSALAALNGEAGPYGEESVLALVAALDSYIPEPERAIDKAFLMPIEDVFSISGRGTVVTGRVEAGIIKVGEEVEIVGIKDTVKTTVTGVEMFRKLLDEGRAGENCGILLRGTKREEVQRGQVLAKPGTIKPHTKFDAEVYVLSKEEGGRHTPFLNGYRPQFYFRTTDVTGAIQLKEGVEMVMPGDNVEMSVELIHPIAMDPGLRFAIREGGRTVGAGVVAKVTA 6mis A 1.98 BS01 E64 A 1 Q19 G23 S24 C25 W26 Y60 K63 G64 G65 A132 N156 H157 Q19 G23 S24 C25 W26 Y60 K63 G64 G65 A132 N156 H157 3.4.22.31 P80884 VPQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDCAVSYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNNERNMMYAVSNQPIAAALDASGNFQHYKRGVFTGPCGTRLNHAIVIIGYGQDSSGKKFWIVRNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDPLYPTLQ 6mjf A 2.20 BS01 SAH A 1 I18 Y97 G98 H99 V102 F103 V104 S128 A129 F170 Q171 Y210 I211 A212 G241 V242 S243 T244 I11 Y90 G91 H92 V95 F96 V97 S121 A122 F163 Q164 Y203 I204 A205 G234 V235 S236 T237 30204409 PGSLIVVGTGIESIGQMTLQALSYIEAASKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRMDTYTQMAELMLKEVRNGLDVVGVFYGHPGVFVNPSHRALAIARSEGYQARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRERPVNVHSHLILFQVGCVGIADFNFSGFDNSKFTILVDRLEQEYGPDHTVVHYIAAMMPHQDPVTDKFTIGQLREPEIAKRVGGVSTFYIPPKARKDINTDIIRLLEFLPAGKVPDKHTQIYPPNQWEPDVPTLPPYGQNEQAAITRLEAHAPPEEYQPLATSKAMTDVMTKLALDPKALAEYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMP 6mjg A 2.12 BS02 ZN A 1 D273 H275 D265 H267 30204409 GSLIVVGTGIESIGQMTLQALSYIEAASKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRMDTYTQMAELMLKEVRNGLDVVGVFYGHPGVFVNPSHRALAIARSEGYQARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRERPVNVHSHLILFQVGCVGIADFNFSGFDNSKFTILVDRLEQEYGPDHTVVHYIAAMMPHQDPVTDKFTIGQLREPEIAKRVGGVSTFYIPPKARKDINTDIIRLLEFLPAGKVPDKHTQIYPPNQWEPDVPTLPPYGQNEQAAITRLEAHAPPEEYQPLATSKAMTDVMTKLALDPKALAEYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLEAASVSSA 6mke A 2.05 BS01 FK5 A 1 Y38 F48 D49 R54 F58 E66 V67 I68 W71 A93 Y94 I103 F111 Y36 F46 D47 R52 F56 E64 V65 I66 W69 A91 Y92 I101 F109 5.2.1.8 A0A2H4A315 TDWIPISQDQRLKKKIITAGSSDEQPPIGSKVSVHYTGTLTSGKKFDSSLDRGQPFVFTLGKGEVIRGWDLGVKSMKKGEKSYFEIPSDYAYGNNAIPGLIPANSTLMFEIELLSWK