5o2l A 2.20 BS01 ADP A 1 N98 P99 Y100 F101 Y107 E152 G154 A155 G156 K157 T158 E159 F163 N200 L310 N94 P95 Y96 F97 Y103 E148 G150 A151 G152 K153 T154 E155 F159 N196 L306 KPVWAPHPTDGFQVGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSETIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKLSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIRERLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSLKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGCNLKNKSTQALEYCAELLGLDQDDLRVSLTTRVMLVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEARLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLSIPRKSKLAIHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNEIDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLI 5o2l A 2.20 BS03 BEF A 1 S153 K157 N200 S203 S204 S149 K153 N196 S199 S200 KPVWAPHPTDGFQVGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSETIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKLSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIRERLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSLKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGCNLKNKSTQALEYCAELLGLDQDDLRVSLTTRVMLVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEARLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLSIPRKSKLAIHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNEIDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLI 5oci A 1.62 BS01 9R8 A 1 N51 D54 A55 D93 I96 G97 M98 L103 L107 G135 F138 V150 W162 T184 V186 N35 D38 A39 D77 I80 G81 M82 L87 L89 G115 F118 V130 W142 T164 V166 29701469 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLNLIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 5ody A 1.15 BS01 9SK A 1 R144 I145 A146 H158 N160 R162 V172 N174 W181 E184 R186 S237 G238 R32 I33 A34 H46 N48 R50 V60 N62 W69 E72 R74 S125 G126 29284090 PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI 5of5 A 1.08 BS04 NO2 A 2 V68 P69 N151 G179 E180 Q181 V62 P63 N145 G173 E174 Q175 1.7.2.1 29755744 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5of5 A 1.08 BS05 NO2 A 3 G324 E325 G318 E319 1.7.2.1 29755744 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5of5 A 1.08 BS06 NO2 A 4 P88 D89 G117 P82 D83 G111 1.7.2.1 29755744 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5of5 A 1.08 BS07 NO2 A 5 V335 K336 V329 K330 1.7.2.1 29755744 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5of5 A 1.08 BS08 NO2 A 6 Q113 N115 E118 Q107 N109 E112 1.7.2.1 29755744 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5of5 A 1.08 BS09 NO2 A 7 V17 D18 L19 T42 N65 V11 D12 L13 T36 N59 1.7.2.1 29755744 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5of6 A 1.08 BS08 NO A 1 P88 D89 P82 D83 1.7.2.1 29755744 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5off A 1.41 BS05 NO2 A 3 R250 D251 R253 E310 R243 D244 R246 E303 1.7.2.1 29755744 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5off A 1.41 BS06 NO2 A 4 I86 N87 G117 E118 E119 I79 N80 G110 E111 E112 1.7.2.1 29755744 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5ofg A 1.49 BS08 NO2 A 6 E47 K48 H60 P199 E40 K41 H53 P192 1.7.2.1 29755744 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5og2 A 1.64 BS08 NO2 A 6 K48 K49 H60 K41 K42 H53 1.7.2.1 29755744 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5og3 A 1.70 BS05 NO2 A 3 N87 G117 E118 E119 N80 G110 E111 E112 1.7.2.1 29755744 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5og3 A 1.70 BS07 NO2 A 5 E47 K48 K49 H60 E40 K41 K42 H53 1.7.2.1 29755744 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5og3 A 1.70 BS09 NO A 1 D98 H135 D91 H128 1.7.2.1 29755744 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5og4 A 1.76 BS05 NO2 A 3 I86 G117 E119 I79 G110 E112 1.7.2.1 29755744 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5og6 A 1.85 BS05 NO2 A 3 G117 E118 E119 G110 E111 E112 1.7.2.1 29755744 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5om2 A 1.47 BS01 DXT B 1 V31 L273 A274 F277 D278 V9 L251 A252 F255 D256 29760101 DRGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKFEMPFDPQDTHQSRFYLSKKKYVMVPMMSLHHLTIPYFRDEELSCTVVQLNYTGNASALFILPDQDKMEEVEAMLSQETLARFFDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATALEVLFQ 5om2 B 1.47 BS01 DXT B 1 D382 H383 W386 S387 D15 H16 W19 S20 29760101 TIVRFNRPFLMIIVDHFTWSIFFMSKVTNPK 5om3 A 2.00 BS01 DXT B 1 L273 S274 F277 D278 L248 S249 F252 D253 29760101 VDRGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKFEMPFDPQDTHQSRFYLSKKKYVMVPMMSLHHLTIPYFRDEELSCTVVQLNYTGNASALFILPDQDKMEEVEAMLSQETLSRFFDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATALFIPLS 5om3 B 2.00 BS01 DXT B 1 H383 W386 H17 W20 29760101 RTIVRFNRPFLMIIVDHFTWSIFFMSKVTNPKQ 5om7 A 1.73 BS01 DM2 A 1 V31 Q242 N244 L273 S274 F277 E278 L280 V9 Q220 N222 L251 S252 F255 E256 L258 29760101 DRGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKFEMPFDPQDTHQSRFYLSKKKYVMVPMMSLHHLTIPYFRDEELSCTVVQLNYTGNASALFILPDQDKMEEVEAMLSQETLSRFFESLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATALEVLFQ 5om7 B 1.73 BS01 DM2 A 1 V381 N383 W386 V15 N17 W20 29760101 RTIVRFNRPFLMIIVDNFTWSIFFMSKVTNPKQ 5ons A 2.14 BS01 III B 1 W39 Q42 H86 K87 Y88 P89 F90 I102 K103 L106 K139 Q140 H141 L143 L170 N171 W175 K178 W39 Q42 H86 K87 Y88 P89 F90 I102 K103 L106 K139 Q140 H141 L143 L170 N171 W175 K178 MFKKFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK 5vt8 B 2.92 BS01 CA B 1 E2497 D2580 V2581 D2583 N2584 D2618 E17 D95 V96 D98 N99 D133 DCRPQFSKPQFSTSVYENEPAGTSVITMLATDQSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDNDEGLNGAVRYSFLKTTGNRDWEYFTIDPISGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDI 5vt8 B 2.92 BS02 CA B 2 N2582 N2584 D2616 D2618 N2622 G2623 D2672 N97 N99 D131 D133 N137 G138 D187 DCRPQFSKPQFSTSVYENEPAGTSVITMLATDQSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDNDEGLNGAVRYSFLKTTGNRDWEYFTIDPISGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDI 5vt8 A 2.92 BS02 CA A 2 N2582 N2584 D2616 D2618 N2622 D2672 N98 N100 D132 D134 N138 D188 DCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDNDEGLNGAVRYSFLKTTGNRDWEYFTIDPISGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDI 5vt8 D 2.92 BS01 CA D 1 E2497 D2580 V2581 D2583 D2618 E17 D95 V96 D98 D133 DCRPQFSKPQFSTSVYENEPAGTSVITMLATDQSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDNDEGLNGAVRYSFLKTTGNRDWEYFTIDPISGLIQTAQVYSLILVASDLGQPVPYETMQPLQVA 5vt8 D 2.92 BS03 CA D 3 C2482 D2512 D2562 L2568 C2 D32 D77 L83 DCRPQFSKPQFSTSVYENEPAGTSVITMLATDQSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDNDEGLNGAVRYSFLKTTGNRDWEYFTIDPISGLIQTAQVYSLILVASDLGQPVPYETMQPLQVA 5vtm X 2.04 BS01 CA X 1 D65 V77 D78 E82 D22 V25 D26 E30 VRQAWHYALGGERLAEAVLRRDLPVDHLGEAWARPMTPFKLDGGELRVRIEDPSGRFNLNGLVRKRKVKPDSVKQFRRLLATLGMKEEIVQGLPDRLADWLDADQNPQGEQGAEDNQYLLEAPAYRAANRSFKDVSELRLLKLSEADYRRLLPFVSALPEDAPLNVNTASVPVLAAMFEIDPGQAENIVDARGREGFQSKDDFTKHLTQKGNVSYAVGTRYFQVISEVSLGDRRQVLVSTLQRGKDGKIRVMARDMGQG 5vtm X 2.04 BS02 CA X 2 D152 D155 D157 N159 E167 D99 D102 D104 N106 E114 VRQAWHYALGGERLAEAVLRRDLPVDHLGEAWARPMTPFKLDGGELRVRIEDPSGRFNLNGLVRKRKVKPDSVKQFRRLLATLGMKEEIVQGLPDRLADWLDADQNPQGEQGAEDNQYLLEAPAYRAANRSFKDVSELRLLKLSEADYRRLLPFVSALPEDAPLNVNTASVPVLAAMFEIDPGQAENIVDARGREGFQSKDDFTKHLTQKGNVSYAVGTRYFQVISEVSLGDRRQVLVSTLQRGKDGKIRVMARDMGQG 5vtm X 2.04 BS03 CA X 3 D152 D155 D157 E167 N182 D99 D102 D104 E114 N129 VRQAWHYALGGERLAEAVLRRDLPVDHLGEAWARPMTPFKLDGGELRVRIEDPSGRFNLNGLVRKRKVKPDSVKQFRRLLATLGMKEEIVQGLPDRLADWLDADQNPQGEQGAEDNQYLLEAPAYRAANRSFKDVSELRLLKLSEADYRRLLPFVSALPEDAPLNVNTASVPVLAAMFEIDPGQAENIVDARGREGFQSKDDFTKHLTQKGNVSYAVGTRYFQVISEVSLGDRRQVLVSTLQRGKDGKIRVMARDMGQG 5vts A 1.57 BS01 HEM A 1 F24 E31 N34 F35 K51 H55 K58 V59 M63 L83 M86 Q88 H89 L92 N96 F97 L100 L127 F24 E31 N34 F35 K51 H55 K58 V59 M63 L83 M86 Q88 H89 L92 N96 F97 L100 L127 GFKQDIATLRGDLRTYAQDIFLAFLNKFPDEKRNFKNYVGKSDQELKSMAKFGDHTEKVFNLMMEVADRATDCVPLASDASTLVQMKQHSGLTTGNFEKLFVALVEYMRASGQSFDSQSWDRFGKNLVSALSSAGMK 5vts B 1.57 BS01 HEM B 1 F24 E31 N34 F35 H55 K58 V59 L62 M63 L83 M86 Q88 H89 L92 N96 F97 F24 E31 N34 F35 H55 K58 V59 L62 M63 L83 M86 Q88 H89 L92 N96 F97 GFKQDIATLRGDLRTYAQDIFLAFLNKFPDEKRNFKNYVGKSDQELKSMAKFGDHTEKVFNLMMEVADRATDCVPLASDASTLVQMKQHSGLTTGNFEKLFVALVEYMRASGQSFDSQSWDRFGKNLVSALSSAGMK 5vtt A 1.90 BS01 HEM A 1 N34 F35 H55 K58 V59 M63 L83 M86 Q88 H89 L92 N96 F97 L127 N34 F35 H55 K58 V59 M63 L83 M86 Q88 H89 L92 N96 F97 L127 GFKQDIATLRGDLRTYAQDIFLAFLNKYPDEKRNFKNFVGKSDQELKSMAKFGDHTEKVFNLMMEVADRATDCVPLASDASTLVQMKQHSGLTTGNFEKLFVALVEYMRASGQSFDSQSWDRFGKNLVSALSSAGMK 5vtt B 1.90 BS01 HEM B 1 E31 N34 F35 H55 K58 V59 L62 M63 L83 M86 Q88 H89 L92 N96 F97 L100 L127 E31 N34 F35 H55 K58 V59 L62 M63 L83 M86 Q88 H89 L92 N96 F97 L100 L127 GFKQDIATLRGDLRTYAQDIFLAFLNKYPDEKRNFKNFVGKSDQELKSMAKFGDHTEKVFNLMMEVADRATDCVPLASDASTLVQMKQHSGLTTGNFEKLFVALVEYMRASGQSFDSQSWDRFGKNLVSALSSAGMK 5vvm A 3.54 BS01 CA A 1 E2162 N2224 E2226 D2265 N2266 E10 N72 E74 D112 N113 NPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPESVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEDVPVGTIILTVTATDADSGNFALIEYSLGDGAINPTTGDIYVLALAKDNPGDVASNRRENSVQVV 5vvm A 3.54 BS02 CA A 2 E2162 E2226 D2262 V2263 D2265 N2266 D2301 E10 E74 D109 V110 D112 N113 D148 NPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPESVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEDVPVGTIILTVTATDADSGNFALIEYSLGDGAINPTTGDIYVLALAKDNPGDVASNRRENSVQVV 5vvm A 3.54 BS03 CA A 3 N2264 N2266 D2299 D2301 N2305 D2353 N111 N113 D146 D148 N152 D200 NPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPESVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEDVPVGTIILTVTATDADSGNFALIEYSLGDGAINPTTGDIYVLALAKDNPGDVASNRRENSVQVV 5vvm A 3.54 BS04 CA A 4 E2284 D2338 E2340 D2374 N2375 E131 D185 E187 D221 N222 NPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPESVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEDVPVGTIILTVTATDADSGNFALIEYSLGDGAINPTTGDIYVLALAKDNPGDVASNRRENSVQVV 5vvm A 3.54 BS05 CA A 5 E2284 E2340 D2371 I2372 D2374 D2407 E131 E187 D218 I219 D221 D250 NPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPESVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEDVPVGTIILTVTATDADSGNFALIEYSLGDGAINPTTGDIYVLALAKDNPGDVASNRRENSVQVV 5vvm A 3.54 BS06 CA A 6 N2373 N2375 D2405 D2407 F2411 D2456 N220 N222 D248 D250 F254 D281 NPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPESVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEDVPVGTIILTVTATDADSGNFALIEYSLGDGAINPTTGDIYVLALAKDNPGDVASNRRENSVQVV 5vvm B 3.54 BS02 CA B 2 E2162 E2226 D2262 V2263 D2265 D2301 E16 E80 D111 V112 D114 D150 SRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREILTALAKDNPGDVASNRRENSVQVV 5vwg A 2.10 BS01 9QG A 1 R45 Q47 R59 H65 N67 R69 N79 W86 E89 R38 Q40 R52 H58 N60 R62 N72 W79 E82 LQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSVKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFS 5vxa A 2.10 BS02 NDP A 1 R24 K25 D26 Y32 H35 K66 K97 L98 K101 D122 N126 D129 L130 W138 H141 R142 E145 Y146 R23 K24 D25 Y31 H34 K65 K96 L97 K100 D121 N125 D128 L129 W137 H140 R141 E144 Y145 3.1.7.2 GSEAAQLLEAADFAARKHRQQRRKDPEGTPYINHPIGVARILTHEAGITDIVVLQAALLHDTVEKTDTTLDEVELHFGAQVRRLVEEVTDDKTLPKLERKRLQVEQAPHSSPGAKLVKLADKLYNLRDLNRCTPEGWSEHRVQEYFEWAAQVVKGLQGTNRQLEEALKHLFKQRGLTI 5vxa B 2.10 BS02 NDP B 1 R24 K25 Y32 H35 K66 K97 K101 N126 D129 L130 W138 R142 Y146 R23 K24 Y31 H34 K65 K96 K100 N125 D128 L129 W137 R141 Y145 3.1.7.2 GSEAAQLLEAADFAARKHRQQRRKDPEGTPYINHPIGVARILTHEAGITDIVVLQAALLHDTVEKTDTTLDEVELHFGAQVRRLVEEVTDDKTLPKLERKRLQVEQAPHSSPGAKLVKLADKLYNLRDLNRCTPEGWSEHRVQEYFEWAAQVVKGLQGTNRQLEEALKHLFKQRGLTI 5w7l A 2.74 BS01 MG A 1 I87 R88 S91 D93 I90 R91 S94 D96 2.7.8.36 GSGMYRNFLKRVIDILGALFLLILTSPIIIATAIFIYFKVSRDVIFTQARPGLNEKIFKMYKFKTMSDERDANGELLPDDQRLGKFGKLIRSLSLDELPQLFNVLKGDMSFIGPRPLLVEYLPIYNETQKHRHDVRPGITGLAQVNGRNAISWEKKFEYDVYYAKNLSFMLDVKIALMTIEKVLK 5w7l B 2.74 BS01 MG B 1 R88 D93 E94 R90 D95 E96 2.7.8.36 SGMYRNFLKRVIDILGALFLLILTSPIIIATAIFIYFKVSRDVIFTQARPGLNEKIFKMYKFKTMSDERDANGELLPDDQRLGKFGKLIRSLSLDELPQLFNVLKGDMSFIGPRPLLVEYLPIYNETQKHRHDVRPGITGLAQVNGRNAISWEKKFEYDVYYAKNLSFMLDVKIALMTIEKVLKR 5wfo N 1.99 BS01 5UU N 1 V875 M878 N879 V883 Y884 F890 L901 H905 V297 M300 N301 V305 Y306 F312 L323 H327 29444450 QMRLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR 5wfp N 2.08 BS01 5UX N 1 V852 M878 N879 V883 Y884 L886 D887 T889 F890 L901 H905 V274 M300 N301 V305 Y306 L308 D309 T311 F312 L323 H327 29444450 QMRLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR 5wfq N 2.26 BS01 5UV N 1 V852 M878 N879 V883 Y884 L886 D887 F890 I893 L901 E902 V277 M303 N304 V308 Y309 L311 D312 F315 I318 L326 E327 29444450 QMRLPSADVYRFAEPDSEENIIFEENMQGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR 5wfr N 2.46 BS01 5UW N 1 M878 N879 V883 Y884 L886 D887 F890 L901 M300 N301 V305 Y306 L308 D309 F312 L323 29444450 QMRLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR 5wm2 A 1.55 BS01 SAL A 1 H255 N256 F257 C261 G328 V350 G352 M353 A354 L358 H237 N238 F239 C243 G310 V332 G334 M335 A336 L340 29742306 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTSVGKTDKKELGRRIAG 5wm2 A 1.55 BS02 AMP A 1 G328 S329 K330 V350 F351 G352 M353 A354 E355 D434 V446 K451 K460 G310 S311 K312 V332 F333 G334 M335 A336 E337 D416 V428 K433 K442 29742306 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTSVGKTDKKELGRRIAG 5wm3 A 1.68 BS01 B5V A 1 N256 F257 G327 G328 S329 K330 V350 F351 G352 M353 A354 L358 D434 V446 K451 K460 N238 F239 G309 G310 S311 K312 V332 F333 G334 M335 A336 L340 D416 V428 K433 K442 29742306 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTSVGKTDKKELGRRIAGQ 5wm3 A 1.68 BS02 MG A 1 S319 L321 G344 S301 L303 G326 29742306 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTSVGKTDKKELGRRIAGQ 5wm4 A 1.78 BS01 B5M A 1 H255 N256 F257 C261 G327 G328 S329 K330 V350 F351 G352 M353 A354 L358 D434 V446 K451 K460 H237 N238 F239 C243 G309 G310 S311 K312 V332 F333 G334 M335 A336 L340 D416 V428 K433 K442 29742306 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTKTDKKELGRRIAGQ 5wm4 A 1.78 BS02 MG A 1 M471 H473 V476 M453 H455 V458 29742306 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTKTDKKELGRRIAGQ 5wm6 A 2.00 BS01 OOB A 1 H255 F257 C261 G327 G328 S329 K330 V350 F351 G352 M353 A354 L358 D434 V446 K451 K460 H237 F239 C243 G309 G310 S311 K312 V332 F333 G334 M335 A336 L340 D416 V428 K433 K442 29742306 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTSVGKTDKKELGRRIA 5wm7 A 1.78 BS01 AMP A 1 G328 S329 K330 V350 F351 G352 M353 A354 D434 K451 K460 G310 S311 K312 V332 F333 G334 M335 A336 D416 K433 K442 29742306 SHMLDGWVPWPESFARRYRAAGYWEGRPLDRLLRERAAADPDRIALVDAAGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRESEIVHVAETAGATAYVIPDVLDGFDHRALARAARKAVPSIEHVLVAGEAAEFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALACPGLLGTLMVGGTVVLAPTPSPEDAFELIEREKVTATAVVPPVALLWLDAVEWEDADLSSLRLLQVGGSKLGAEPAARVRPALGCTLQQVFGMAEGLLNYTRLDDPSDLVIQTQGRPLSPDDEIRVVDEDGRDVAPGETGELLTRGPYTLRGYYRAPEHNARTFSDDGFYRTGDLVRVLPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMPDATMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVMDAFPRTSVGKTDKKELGRRIA 5wxu A 1.70 BS01 IAC A 1 G119 C120 P121 E122 G88 C89 P90 E91 28680092 SRQSSPQSGIGECDLQRVNPLEPAHRIQHEAGYSEIWDPTSRELQCAGIDATRHVIENRGLFVPSYNNAPMLIIVVQGHGILGAVFPGCPETFQSFHPTDQTFRDQHQKVHFIRQGDVIALPAGIVHWAYNEATEKLVLLVIHDLSNRENQLDQNLRRYFLGGNQKNLLWNNVFQPLDPQFLGRASGVNSEIIKKLQSENDFRGYMVRVRDGLRLVRPSSEEGYEETLCTVRIKENLLNPERADIYTSRGGTVSTLNSYNLPILRKLQLSANREYLYPNAMIVPEWNNNAHSISYVTRGSGRLQVGGSSKSTVYDGDVRQGQLFIIPQNYVYLKQAGPQGLELYTVKTNDRAKATALVGRTSVIRAVPLDVWINVFQLTQDEARSLKYNREEITVLDPE 5wxu B 1.70 BS01 IAC B 1 G119 C120 P121 G88 C89 P90 28680092 SRQSSPQSGIGECDLQRVNPLEPAHRIQHEAGYSEIWDPTSRELQCAGIDATRHVIENRGLFVPSYNNAPMLIIVVQGHGILGAVFPGCPETFQSFHPTDQTFRDQHQKVHFIRQGDVIALPAGIVHWAYNEATEKLVLLVIHDLSNRENQLDQNLRRYFLGGNQKNLLWNNVFQPLDPQFLGRASGVNSEIIKKLQSENDFRGYMVRVRDGLRLVRPSSEEGYEETLCTVRIKENLLNPERADIYTSRGGTVSTLNSYNLPILRKLQLSANREYLYPNAMIVPEWNNNAHSISYVTRGSGRLQVGGSSKSTVYDGDVRQGQLFIIPQNYVYLKQAGPQGLELYTVKTNDRAKATALVGRTSVIRAVPLDVWINVFQLTQDEARSLKYNREEITVLDPEL 5wxu D 1.70 BS01 IAC B 1 R422 R427 R357 R362 28680092 SRQSSPQSGIGECDLQRVNPLEPAHRIQHEAGYSEIWDPTSRELQCAGIDATRHVIENRGLFVPSYNNAPMLIIVVQGHGILGAVFPGCPETFQSFHPTTFRDQHQKVHFIRQGDVIALPAGIVHWAYNEATEKLVLLVIHDLSNRENQLDQNLRRYFLGGNQKNLLWNNVFQPLDPQFLGRASGVNSEIIKKLQSENDFRGYMVRVRDGLRLVRPSSEGYEETLCTVRIKENLLNPERADIYTSRGGTVSTLNSYNLPILRKLQLSANREYLYPNAMIVPEWNNNAHSISYVTRGSGRLQVGGSSKSTVYDGDVRQGQLFIIPQNYVYLKQAGPQGLELYTVKTNDRAKATALVGRTSVIRAVPLDVWINVFQLTQDEARSLKYNREEITVLDPE 5wxu F 1.70 BS01 IAC A 1 R422 T423 R358 T359 28680092 SRQSSPQSGIGECDLQRVNPLEPAHRIQHEAGYSEIWDPTSRELQCAGIDATRHVIENRGLFVPSYNNAPMLIIVVQGHGILGAVFPGCPETFQSFHPTTFRDQHQKVHFIRQGDVIALPAGIVHWAYNEATEKLVLLVIHDLSNRENQLDQNLRRYFLGGNQKNLLWNNVFQPLDPQFLGRASGVNSEIIKKLQSENDFRGYMVRVRDGLRLVRPSSEEGYEETLCTVRIKENLLNPERADIYTSRGGTVSTLNSYNLPILRKLQLSANREYLYPNAMIVPEWNNNAHSISYVTRGSGRLQVGGSSKSTVYDGDVRQGQLFIIPQNYVYLKQAGPQGLELYTVKTNDRAKATALVGRTSVIRAVPLDVWINVFQLTQDEARSLKYNREEITVLDPEL 5wxu F 1.70 BS02 IAC B 1 G119 P121 E122 G88 P90 E91 28680092 SRQSSPQSGIGECDLQRVNPLEPAHRIQHEAGYSEIWDPTSRELQCAGIDATRHVIENRGLFVPSYNNAPMLIIVVQGHGILGAVFPGCPETFQSFHPTTFRDQHQKVHFIRQGDVIALPAGIVHWAYNEATEKLVLLVIHDLSNRENQLDQNLRRYFLGGNQKNLLWNNVFQPLDPQFLGRASGVNSEIIKKLQSENDFRGYMVRVRDGLRLVRPSSEEGYEETLCTVRIKENLLNPERADIYTSRGGTVSTLNSYNLPILRKLQLSANREYLYPNAMIVPEWNNNAHSISYVTRGSGRLQVGGSSKSTVYDGDVRQGQLFIIPQNYVYLKQAGPQGLELYTVKTNDRAKATALVGRTSVIRAVPLDVWINVFQLTQDEARSLKYNREEITVLDPEL 5xoh A 2.20 BS01 SAH A 1 F158 M175 S179 G203 D226 L227 D246 M247 K260 I262 W266 F151 M168 S172 G196 D219 L220 D239 M240 K253 I255 W259 2.1.1.69 PSQDEEACVLAIQLATSTVLPMILKSAIELDILNTISKAGPGNYLSPSDLASKLLMSNPHAPIMLERILRVLATYKVLGCKPSELSDGEVEWLYCWTPVCKFLSNNEDGASIAPLLLVHQDQVPMKSWYHLTDAILDGGTAFNKAYGMNIFDYASQDPQFNKVFNRSMAGHSTITMKKILETYNGFEGLKSIVDVGGGSGATLNMIISKYPTIKGINFDLPHVVGDSPIHPGVEHVGGDMFASVPKGDAIFLKWIFHSWSDEDCLRILKNCYEALADNKKVIVAEFIIPEVPGGSDDATKSVVHLDAVMLAYVPGGKERTEKEFEALATSAGFKSFRKVCCAFNTWIM 5xoh A 2.20 BS02 8B6 A 1 L122 H126 I157 F158 F171 M175 W261 H264 S265 L312 M316 Y319 V320 L115 H119 I150 F151 F164 M168 W254 H257 S258 L305 M309 Y312 V313 2.1.1.69 PSQDEEACVLAIQLATSTVLPMILKSAIELDILNTISKAGPGNYLSPSDLASKLLMSNPHAPIMLERILRVLATYKVLGCKPSELSDGEVEWLYCWTPVCKFLSNNEDGASIAPLLLVHQDQVPMKSWYHLTDAILDGGTAFNKAYGMNIFDYASQDPQFNKVFNRSMAGHSTITMKKILETYNGFEGLKSIVDVGGGSGATLNMIISKYPTIKGINFDLPHVVGDSPIHPGVEHVGGDMFASVPKGDAIFLKWIFHSWSDEDCLRILKNCYEALADNKKVIVAEFIIPEVPGGSDDATKSVVHLDAVMLAYVPGGKERTEKEFEALATSAGFKSFRKVCCAFNTWIM 5xt2 A 2.65 BS01 MG A 1 D12 D55 D10 D53 29636388 TKGHIYVIDDDAAMRDSLNFLLDSAGFGVTLFDDAQAFLDALPGLSFGCVVSDVRMPGLDGIELLKRMKAQQSPFPILIMTGHGDVPLAVEAMKLGAVDFLEKPFEDDRLTAMIESAIRQAEPAAKSEAVAQDIAARVASLSPRERQVMEGLIAGLSNKLIAREYDISPRTIEVYRANVMTKMQANSLSELVRLAMRAGMLN 5xt2 D 2.65 BS01 MG D 1 D11 D12 D55 D9 D10 D53 29636388 TKGHIYVIDDDAAMRDSLNFLLDSAGFGVTLFDDAQAFLDALPGLSFGCVVSDVRMPGLDGIELLKRMKAQQSPFPILIMTGHGDVPLAVEAMKLGAVDFLEKPFEDDRLTAMIESAIRQAEPAAKSEAVAQDIAARVASLSPRERQVMEGLIAGLSNKLIAREYDISPRTIEVYRANVMTKMQANSLSELVRLAMRAGMLN 5xyz A 2.64 BS01 GYL A 1 L408 V416 A428 K430 T474 E475 Y476 M477 G480 C481 L528 S538 F540 L15 V16 A28 K30 T68 E69 Y70 M71 G74 C75 L119 S129 F131 2.7.10.2 28945083 SWEIDPKDLTFLKELVKYGKWRGQYDVAIKMIKMSDEEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLRERFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRFPVRWSPPEVLMFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMD 5xyz B 2.64 BS01 GYL B 1 V416 A428 K430 I472 T474 E475 M477 G480 C481 L528 S538 F540 V16 A28 K30 I68 T70 E71 M73 G76 C77 L124 S134 F136 2.7.10.2 28945083 SWEIDPKDLTFLKELVKYGKWRGQYDVAIKMIKMSEDEIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRFPVRWSPPEVLMSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMD 5ya8 A 2.30 BS01 NAD A 1 I13 T15 G16 F17 M18 D45 M46 T82 T83 P84 N85 L87 H88 E105 K106 G132 N134 W177 R178 H195 F322 I7 T9 G10 F11 M12 D39 M40 T76 T77 P78 N79 L81 H82 E99 K100 G126 N128 W171 R172 H189 F316 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDLPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5ya8 A 2.30 BS02 INS A 1 K106 Y135 Y163 E165 R178 D191 L192 H195 K100 Y129 Y157 E159 R172 D185 L186 H189 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDLPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5ya8 C 2.30 BS01 NAD C 1 G14 T15 G16 F17 M18 D45 T82 T83 P84 N85 H88 E105 K106 G132 N134 H195 G8 T9 G10 F11 M12 D39 T76 T77 P78 N79 H82 E99 K100 G126 N128 H189 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDLPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5ya8 D 2.30 BS01 NAD D 1 I13 G14 T15 G16 F17 M18 D45 T82 T83 P84 N85 L87 H88 E105 K106 P107 G132 N134 W177 R178 H195 I7 G8 T9 G10 F11 M12 D39 T76 T77 P78 N79 L81 H82 E99 K100 P101 G126 N128 W170 R171 H188 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5yap A 1.80 BS02 8S0 A 1 K106 Y135 Y163 E165 Y167 D191 H195 K100 Y129 Y157 E159 Y161 D185 H189 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDLPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5yap C 1.80 BS01 NAI C 1 I13 G14 T15 G16 F17 M18 D45 M46 K50 T82 T83 P84 N85 L87 H88 E105 K106 G132 N134 H195 I7 G8 T9 G10 F11 M12 D39 M40 K44 T76 T77 P78 N79 L81 H82 E99 K100 G126 N128 H189 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDLPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5yaq A 1.99 BS01 NAD A 1 I13 T15 G16 F17 M18 D45 M46 K50 T82 T83 P84 N85 L87 H88 E105 K106 G132 N134 H195 I7 T9 G10 F11 M12 D39 M40 K44 T76 T77 P78 N79 L81 H82 E99 K100 G126 N128 H189 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDLPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5yaq B 1.99 BS02 ISE B 1 K106 Y135 Y163 E165 R178 D191 H195 K100 Y129 Y157 E159 R172 D185 H189 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDLPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5yaq C 1.99 BS01 NAD C 1 T15 G16 F17 M18 D45 M46 T82 T83 P84 N85 L87 H88 E105 K106 P107 G132 N134 H195 T9 G10 F11 M12 D39 M40 T76 T77 P78 N79 L81 H82 E99 K100 P101 G126 N128 H189 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDLPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5yaq C 1.99 BS02 ISE C 1 K106 Y135 Y163 E165 D191 H195 K100 Y129 Y157 E159 D185 H189 ALGVALIGTGFMGKCHAMAWRNVATAFGGLPPRLEVLADMPADKAHSLASSFGFARGTADWREAVSDPAVDVVSITTPNGLHREMAEAALAAGKHVWLEKPMALSVEDAQAMEAAARASDRRTIIGYNYTRSPAFRAAVDLIAEGAIGRPIHFRGMYDEDYMADPDLPWSWRLTRKDGGLGALGDLGCHLVSVMVSLMGPVARVYAQADTVITDRPHQGGTARVENEDQAQALIRFASGTSGEFSCSRVARGYRCRLAWEVQGTEGTLRFDQERMNELWLYQPGRPEIDGFRRILTGPAQPGFAAFCPGGGHNFGFNEQKVVEAEMLRQAIAGRGKAWPDFTDGLTIERVIHGMATSAQTGQPVNF 5ydl A 2.40 BS01 DUV A 1 G91 G92 F145 S173 L174 R198 I199 I202 A203 M266 H271 G97 G98 F151 S179 L180 R204 I205 I208 A209 M272 H277 29536601 NLYFQGSGRRLVLPVSARTSGALRGQAHALARRLEERPGLRLDDVAGALRADRPALRHRLTVSASSVPEAVEALRAAVPAVPPVPDEPPKVAFLLPGGGTQYVGMGSGLYRENDVYRDTVDRCAAVLRPALGSDLRTALFEEVEPGSTAAFMALFVTEYALARTLMEEGVRPDALIGHSLGEYTAACLAGVMEIDEALPVVAERIRLIASSGGATVGVAACADTVLPLLGEGLSLAAVNSPVACTVAGDTDAVDRLEAELTRRGVPFRRLRMPAAAHSHVLDPILESFAGHLRTLTLRPPRIPYVTNVTGDWATDAQATDVGHWVDHTRRTVRFADGIAALWERERPVLVEIGPGDSLTKLARARLDGEGPVTVTTMRHAKAQAADGFVLAEALGRLWSAGVDAALPH 5ydm A 2.50 BS01 DUW A 1 G91 G92 S173 L174 R198 I202 M266 A268 A270 H271 G97 G98 S179 L180 R204 I208 M272 A274 A276 H277 29536601 NLYFQGSGRRLVLPVSARTSGALRGQAHALARRLEERPGLRLDDVAGALRADRPALRHRLTVSASSVPEAVEALRAAVPAVPPVPDEPPKVAFLLPGGGTQYVGMGSGLYRENDVYRDTVDRCAAVLRPALGSDLRTALFEEVEPGSTAAFMALFVTEYALARTLMEEGVRPDALIGHSLGEYTAACLAGVMEIDEALPVVAERIRLIASSGGATVGVAACADTVLPLLGEGLSLAAVNSPVACTVAGDTDAVDRLEAELTRRGVPFRRLRMPAAAHSHVLDPILESFAGHLRTLTLRPPRIPYVTNVTGDWATDAQATDVGHWVDHTRRTVRFADGIAALWERERPVLVEIGPGDSLTKLARARLDGEGPVTVTTMRHAKAQAADGFVLAEALGRLWSAGVDAALPH 5ygy A 2.30 BS01 0B6 A 1 G11 Q12 G13 L30 D32 G34 Y71 F108 I118 D228 S229 G230 T231 T232 A335 G18 Q19 G20 L37 D39 G41 Y78 F115 I125 D224 S225 G226 T227 T228 A331 3.4.23.46 GRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 5yht A 2.87 BS01 ZN A 1 E67 D83 D213 E64 D80 D210 3.1.3.15 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5yht A 2.87 BS02 ZN A 2 D44 E67 E68 D83 I85 D41 E64 E65 D80 I82 3.1.3.15 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5yht A 2.87 BS03 HSA A 1 D44 E67 D83 I85 D86 G87 T88 D189 E206 D213 D41 E64 D80 I82 D83 G84 T85 D186 E203 D210 3.1.3.15 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5yht A 2.87 BS04 HSO B 1 P96 V97 Y187 L191 P93 V94 Y184 L188 3.1.3.15 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5yht B 2.87 BS01 HSO B 1 P96 V97 L120 L191 P84 V85 L108 L179 3.1.3.15 DLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTRDRPGDGVLEEFFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5yip A 1.85 BS01 III B 1 Y5 E17 P30 K46 K48 Y49 L50 D54 Q59 F60 F62 L63 K66 R67 F104 Y11 E23 P36 K52 K54 Y55 L56 D60 Q65 F66 F68 L69 K72 R73 F110 GPGSEFMKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK 5yiq A 2.60 BS01 III D 1 I23 H27 K30 P32 K49 K51 F52 L53 V54 P55 E62 I66 R70 F108 I19 H23 K26 P28 K45 K47 F48 L49 V50 P51 E58 I62 R66 F104 KTFKQRRSFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESERDEDGFLYMVYASQETF 5yiq A 2.60 BS02 ZN A 1 H86 E102 H82 E98 KTFKQRRSFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESERDEDGFLYMVYASQETF 5yiq A 2.60 BS03 ZN A 2 E97 E100 E93 E96 KTFKQRRSFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESERDEDGFLYMVYASQETF 5yir D 2.75 BS01 III C 1 E17 I21 Y25 R28 P30 K46 K48 Y49 L50 P52 D54 Q59 F62 L63 R67 F104 E17 I21 Y25 R28 P30 K46 K48 Y49 L50 P52 D54 Q59 F62 L63 R67 F104 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL 5yir A 2.75 BS01 III G 1 Y5 H9 E17 I21 Y25 P30 I32 K46 K48 Y49 L50 P52 D54 L55 Q59 F62 L63 K66 R67 F104 Y5 H9 E17 I21 Y25 P30 I32 K46 K48 Y49 L50 P52 D54 L55 Q59 F62 L63 K66 R67 F104 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL 5yir B 2.75 BS01 III H 1 E17 I21 Y25 P30 K46 K48 Y49 L50 P52 D54 T56 Q59 F62 K66 R67 F104 E17 I21 Y25 P30 K46 K48 Y49 L50 P52 D54 T56 Q59 F62 K66 R67 F104 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL 5yis A 2.20 BS01 III C 1 I23 H27 I34 K49 K51 F52 L53 P55 H57 V58 S61 E62 K65 I66 R70 V91 S92 F108 I19 H23 I30 K45 K47 F48 L49 P51 H53 V54 S57 E58 K61 I62 R66 V87 S88 F104 KTFKQRRSFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESERDEDGFLYMVYASQE 5yis B 2.20 BS01 III D 1 I23 H27 K30 P32 K49 K51 F52 L53 P55 V58 I66 R70 F108 I20 H24 K27 P29 K46 K48 F49 L50 P52 V55 I63 R67 F105 EKTFKQRRSFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESERDEDGFLYMVYASQETFGTAMAV 5yjg A 2.40 BS01 CYS A 1 D38 Q39 C60 Y64 D1 Q2 C23 Y27 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS02 CA A 1 D258 K294 D221 K257 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS03 CA A 2 G378 K379 G341 K342 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS04 CA A 3 H100 Y102 G103 H63 Y65 G66 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS05 CA A 4 T176 K177 H198 T139 K140 H161 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS06 CA A 5 N445 Y462 V571 F572 N408 Y425 V534 F535 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS07 MG A 1 A110 T112 T113 P137 S138 N139 W142 A73 T75 T76 P100 S101 N102 W105 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS08 MG A 2 D246 L247 S249 F250 P274 T275 N276 F279 D209 L210 S212 F213 P237 T238 N239 F242 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS09 MG A 3 Q380 Q381 T383 F384 P408 V409 N410 F413 Q343 Q344 T346 F347 P371 V372 N373 F376 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS10 MG A 4 F509 T511 F512 P536 N538 F541 F472 T474 F475 P499 N501 F504 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS11 MG A 5 C208 R228 C311 S312 E313 D350 C171 R191 C274 S275 E276 D313 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS12 MG A 6 G574 E597 L602 S612 D613 G537 E560 L565 S575 D576 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjg A 2.40 BS13 MG A 7 F195 N197 T205 V206 N207 C208 C311 F158 N160 T168 V169 N170 C171 C274 DQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjh A 2.96 BS01 MG A 1 I98 D99 T104 I107 I217 A218 I61 D62 T67 I70 I180 A181 DQGPNVCALQQILGTKKKYFSTAKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjh A 2.96 BS02 MG A 2 R458 G529 D530 V571 T617 R421 G492 D493 V534 T580 DQGPNVCALQQILGTKKKYFSTAKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjh A 2.96 BS04 MG A 4 L247 S249 F250 P274 T275 F279 L210 S212 F213 P237 T238 F242 DQGPNVCALQQILGTKKKYFSTAKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjh A 2.96 BS09 MG A 9 F195 N197 T205 N207 C208 C311 F158 N160 T168 N170 C171 C274 DQGPNVCALQQILGTKKKYFSTAKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yjh A 2.96 BS11 CA A 2 N445 V571 N408 V534 DQGPNVCALQQILGTKKKYFSTAKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPA 5yly A 1.76 BS01 FAD A 1 H640 R659 A660 Y661 T662 V676 V677 K678 Y680 K681 H685 F688 G691 G692 K693 F694 S695 T743 T746 P747 H45 R58 A59 Y60 T61 V75 V76 K77 Y79 K80 H84 F87 G90 G91 K92 F93 S94 T142 T145 P146 29371148 APFLNPKKQKAAELKEKIKISHDVTLFRFGLEHDEQLLGLPTGKHMLIRKKVTEVVMRAYTPTTANETRGHFDLVVKIYKANVHPKFPEGGKFSQILEALEVGDTVEVKGPIGHFHYDRPGHYKNHKLESEVKRINMIAGGTGLTPMYQVMKAILSNPSDLTEIRLLYANQTEADILLRPELEALAKSHPDRVKIHYTVDRPTPGWKYSSGFIDLDMCERALFRYEPGTISVLCGPPPMLKFACHPNLEKMGFEKGVTSIEF 5yu8 A 3.80 BS01 ADP A 1 G13 S14 G15 L16 K18 G156 D157 R210 K213 E214 G301 G302 M305 Y306 K336 G8 S9 G10 L11 K13 G141 D142 R195 K198 E199 G286 G287 M290 Y291 K321 29749375 TALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHKDSYVGDEAQSKRGILTLKYPIEGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 5yws A 2.00 BS01 NUC C 1 D18 L19 E20 A21 G23 L24 P25 S26 I84 T85 H124 N125 R128 Y129 I156 R174 S176 Y177 S178 L179 H195 D14 L15 E16 A17 G19 L20 P21 S22 I80 T81 H120 N121 R124 Y125 I152 R170 S172 Y173 S174 L175 H191 3.1.11.2 29734329 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSPSGNGSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 5ywt A 1.70 BS01 NUC C 1 D18 L19 E20 A21 G23 L24 I84 T85 H124 N125 R128 Y129 A157 K160 S176 Y177 S178 L179 H195 D200 D14 L15 E16 A17 G19 L20 I80 T81 H120 N121 R124 Y125 A153 K156 S162 Y163 S164 L165 H181 D186 3.1.11.2 29734329 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGTP 5ywt A 1.70 BS03 CO A 1 K211 P212 Q213 A214 K197 P198 Q199 A200 3.1.11.2 29734329 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGTP 5ywt A 1.70 BS04 CO A 2 Q12 H40 P116 Q8 H36 P112 3.1.11.2 29734329 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGTP 5ywt B 1.70 BS01 NUC D 1 D18 L19 E20 A21 G23 L24 A81 I84 T85 H124 N125 Y129 I156 S176 Y177 S178 L179 H195 D200 D11 L12 E13 A14 G16 L17 A74 I77 T78 H117 N118 Y122 I149 S160 Y161 S162 L163 H179 D184 3.1.11.2 29734329 HGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGTP 5ywt B 1.70 BS03 CO B 1 S78 P79 G80 S71 P72 G73 3.1.11.2 29734329 HGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGTP 5ywu A 3.40 BS01 NUC C 1 L19 E20 A21 G23 L24 P25 S26 A81 I84 T85 H124 N125 R128 Y129 S176 Y177 S178 L179 L15 E16 A17 G19 L20 P21 S22 A77 I80 T81 H120 N121 R124 Y125 S167 Y168 S169 L170 3.1.11.2 29734329 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSPRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYG 5ywu B 3.40 BS01 NUC D 1 D18 L19 E20 A21 G23 L24 S26 A81 I84 H124 N125 R128 Y129 S176 Y177 S178 L179 H195 D14 L15 E16 A17 G19 L20 S22 A77 I80 H120 N121 R124 Y125 S172 Y173 S174 L175 H191 3.1.11.2 29734329 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSPSGNGSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 5ywu B 3.40 BS02 MG B 1 D18 L19 D130 D14 L15 D126 3.1.11.2 29734329 TLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSPSGNGSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 5ywv A 2.30 BS01 NUC C 1 L19 E20 A21 G23 L24 P25 S78 A81 I84 T85 H124 N125 Y129 I156 S176 Y177 S178 L179 H195 L16 E17 A18 G20 L21 P22 S75 A78 I81 T82 H121 N122 Y126 I153 S166 Y167 S168 L169 H185 3.1.11.2 29734329 QTLPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGTP 5ywv B 2.30 BS01 NUC D 1 E20 A21 G23 L24 P25 S78 G80 A81 I84 T85 H124 N125 R128 Y129 I156 S176 Y177 S178 L179 H195 E15 A16 G18 L19 P20 S73 G75 A76 I79 T80 H119 N120 R123 Y124 I151 S166 Y167 S168 L169 H185 3.1.11.2 29734329 LPHGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASSSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYG 5zgs A 2.20 BS01 HEM A 1 M101 G104 Q105 D108 D112 F113 A114 E258 Q259 T344 F347 R348 G350 H351 V354 L376 F380 L417 L433 I436 R440 M101 G104 Q105 D108 D112 F113 A114 E258 Q259 T344 F347 R348 G350 H351 V354 L376 F380 L417 L433 I436 R440 1.11.1.7 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 5zon A 1.94 BS02 ZN A 2 E67 D83 D86 D213 E65 D81 D84 D211 3.1.3.15 29752410 HDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5zon A 1.94 BS03 PO4 A 1 D44 E67 D83 I85 D86 G87 T88 D42 E65 D81 I83 D84 G85 T86 3.1.3.15 29752410 HDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5zon B 1.94 BS01 ZN B 1 D86 D189 D213 D78 D178 D202 3.1.3.15 29752410 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGETTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDARPHRLSVSSVAELHSASLSFSSLSGWPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5zon B 1.94 BS03 PO4 B 1 D86 G87 T88 D189 D213 D78 G79 T80 D178 D202 3.1.3.15 29752410 DDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGETTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDARPHRLSVSSVAELHSASLSFSSLSGWPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5zon C 1.94 BS04 PO4 D 1 R183 R185 R181 R183 3.1.3.15 29752410 HDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5zon D 1.94 BS01 ZN D 1 D86 D189 D78 D178 3.1.3.15 29752410 HDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPDGVLGETTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDARPHRLSVSSVAELHSASLSFSSLSGWAGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5zon D 1.94 BS03 PO4 D 2 G87 T88 K89 D189 G79 T80 K81 D178 3.1.3.15 29752410 HDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPDGVLGETTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDARPHRLSVSSVAELHSASLSFSSLSGWAGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDEVLTRLN 5zq4 B 2.22 BS01 AMP B 1 R334 Y343 W390 N400 Q401 H403 M404 L407 Y420 Q424 R113 Y122 W169 N179 Q180 H182 M183 L186 Y199 Q203 29731171 SVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREESSGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQT 5zq4 A 2.22 BS01 AMP A 1 Y343 W390 N400 Q401 H403 M404 Y420 Q424 Y122 W169 N179 Q180 H182 M183 Y199 Q203 29731171 SVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREESSGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQT 5zq6 A 3.01 BS01 ADP A 1 H274 R334 Y343 W390 N400 H403 M404 L407 K411 Y420 Q424 H53 R113 Y122 W169 N179 H182 M183 L186 K190 Y199 Q203 29731171 SVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREEGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQTKITPIKRAFQSSSEKARRQPNMDEIAAARIVQQIMANPDCIHDDHVFLNGQKLEEKFFRDLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVKLGETWEKTIRSGGGVTQIKHDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLMDTSRSPAPKTLFRGLDLSEEFKNKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIEVPRTIFGSNTIFEILDPDGLLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLVAVKSPDFTPRHESGYAVGPLLKMQTPKLEEIQRLVEQAREEPDLERVFNLQSRVARQAKFSTESGYKTFLNEKVAPVLEQSLNGLLDNNVTILGKVLSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILPALAQCQNALEKQNIAGALQALRNIPSL 5zq6 C 3.01 BS01 ADP C 1 H274 R334 Y343 W390 N400 Q401 H403 M404 Q424 H52 R112 Y121 W168 N178 Q179 H181 M182 Q202 29731171 VPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIPIRELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQTKITPIKRAFQSSSEKARRQPNMDEIAAARIVQQIMANPDCIHDDHVFLNGQKLEEKFFRDLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVKLGETWEKTIRSGGGVTQIKHDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLMDTSRSPAPKTLFRGLDLSEEFKNKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIEVPRTIFGSNTIFEILDPDGLLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLVAVKSPDFTPRHESGYAVGPLLKMQTPKLEEIQRLVEQAREEPDLERVFNLQSRVARQAKFSTESGYKTFLNEKVAPVLEQSLNGLLDNNVTILGKVLSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILPALAQCQNALEKQNIAGALQALRNIPSL 5zq7 A 2.85 BS01 NAD A 1 Q708 H714 N718 Q722 R724 R761 G762 L763 D764 F769 V808 S815 T816 P823 F827 E855 E857 Q478 H484 N488 Q492 R494 R531 G532 L533 D534 F539 V578 S585 T586 P593 F597 E625 E627 29731171 SVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREEGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQTKITPIKRAFQSSSEKARRQPNMDEIAAARIVQQIMANPDCIHDDHVFLNGQKLEEKFFRDLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVKLGETWEKTIRSGGGVTQIKHDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLMDTSRSPAPKTLFRGLDLSEEFKNKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIEVPRTIFGSNTIFEILDPDGLLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLVAVKSPDFTPRHESGYAVGPLLKMQTPKLEEIQRLVEQAREEPDLERVFNLQSRVARQAKFSTESGYKTFLNEKVAPVLEQSLNGLLDNNVTILGKVLSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILPALAQCQNALEKQNIAGALQALRNIPSL 5zq7 C 2.85 BS01 NAD C 1 Q708 H714 N718 Q722 R724 R761 G762 L763 D764 S815 T816 V822 P823 F827 E855 E857 Q474 H480 N484 Q488 R490 R527 G528 L529 D530 S581 T582 V588 P589 F593 E621 E623 29731171 VPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIRELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQTKITPIKRAFQSSSEKARRQPNMDEIAAARIVQQIMANPDCIHDDHVFLNGQKLEEKFFRDLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVKLGETWEKTIRSGGGVTQIKHDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLMDTSRSPAPKTLFRGLDLSEEFKNKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIEVPRTIFGSNTIFEILDPDGLLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLVAVKSPDFTPRHESGYAVGPLLKMQTPKLEEIQRLVEQAREEPDLERVFNLQSRVARQAKFSTESGYKTFLNEKVAPVLEQSLNGLLDNNVTILGKVLSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILPALAQCQNALEKQNIAGALQALRNIPSL 6b5d A 3.10 BS01 ADP A 1 I195 I196 G236 T237 G238 K239 T240 L241 L370 G398 I32 I33 G73 T74 G75 K76 T77 L78 L188 G216 3.6.4.3 29752405 SFDASAYDAYIVQAVRGTMATNTENTMSLDDIIGMHDVKQVLHEAVTLPLLVPEFFQGLRSPWKAMVLAGPPGTGKTLIARAIASESSSTFFTVSSTDLSSKSEKIVRLLFELARFYAPSIIFIDEIDTLGEASRRVKSEFLVQMDGSQRVFVLAATNIPWELDEALRRRFEKRIFIPLPDIDARKKLIEKSMEGTPKSDEINYDDLAARTEGFSGADVVSLCRTAAINVLRRYDTKSLRGGELTAAMESLKAELVRNIDFEAALQAVSPSAGPDTMLKCKEWCDS 6bbd A 1.90 BS03 GOL A 1 E321 N323 E332 N344 D345 K346 E117 N119 E128 N140 D141 K142 TALRQQVETLQGQVQRLQKAFSQYKKVELFPNGRGVGEKIFKTGGFEKTFQDAQQVCTQAGGQMASPRSETENEALSQLVTAQNKAAFLSMTDIKTEGNFTYPTGEPLVYANWAPGEPNNNGGSSGAENCVEIFPNGKWNDKACGELRLVICEF 6bbn A 3.51 BS01 GTP A 1 G10 Q11 A12 Q15 E71 D98 A99 A100 N101 S140 G143 G144 T145 G146 E183 N206 Y224 N228 I231 G9 Q10 A11 Q14 E70 D97 A98 A99 N100 S139 G142 G143 T144 G145 E182 N205 Y223 N227 I230 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 6bbn B 3.51 BS01 GDP B 1 G10 Q11 C12 A99 S140 G142 G143 G144 T145 G146 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 A97 S138 G140 G141 G142 T143 G144 V175 D177 E181 N204 Y222 N226 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6bbn C 3.51 BS01 GTP C 1 G10 Q11 A12 Q15 I16 D98 A99 A100 N101 S140 G143 T145 V177 S178 N206 Y224 N228 G10 Q11 A12 Q15 I16 D94 A95 A96 N97 S136 G139 T141 V173 S174 N202 Y220 N224 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 6bbn D 3.51 BS01 GDP D 1 G10 Q11 C12 S140 G143 G144 T145 G146 V177 S178 E183 N206 Y224 L227 N228 G10 Q11 C12 S138 G141 G142 T143 G144 V175 S176 E181 N204 Y222 L225 N226 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6bbn E 3.51 BS01 ANP E 1 R229 Q314 T315 G316 S317 G318 K319 T320 H321 S432 S433 L458 A459 G460 R69 Q154 T155 G156 S157 G158 K159 T160 H161 S258 S259 L284 A285 G286 SNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKE 6bbn E 3.51 BS02 MG E 1 T320 S433 D457 L458 T160 S259 D283 L284 SNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKE 6bdy A 1.51 BS01 SFG A 1 D946 P949 R1094 E1097 R1134 P1135 A1136 Y1139 P1140 A1141 Y1189 Y1190 D46 P49 R194 E197 R234 P235 A236 Y239 P240 A241 Y289 Y290 2.1.1.13 29733595 TPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDA 6bm5 A 1.50 BS01 SAM A 1 D946 R1094 E1097 R1134 P1135 A1136 Y1139 P1140 A1141 Y1189 Y1190 D46 R194 E197 R234 P235 A236 Y239 P240 A241 Y289 Y290 2.1.1.13 29733595 TPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYD 6bsu A 1.50 BS01 MN A 1 D227 D229 H377 D112 D114 H262 2.4.2.39 PYSLGPKISDWDEQRRDWLKQNPSFPNFVAPNKPRVLLVTGSAPKPCENPVGDHYLLKSIKNKIDYCRIHGIEIFYNMALLDAEMAGFWAKLPLIRKLLLSHPEIEFLWWMDSDAMFTDMVFELPWERYKDYNLVMHGWNEMVYDQKNWIGLNTGSFLLRNSQWSLDLLDAWAPMGPKGKIREEAGKVLTRELKDRPAFEADDQSAMVYLLATEREKWGGKVYLESGYYLHGYWGILVDRYEEMIENHKPGFGDHRWPLVTHFVGCKPCGKFGDYPVERCLRQMDRAFNFGDNQILQMYGFTHKSLGSRRVKPTRNQTDRPLDAKDEFGLLHPPFKA 6bsv A 2.43 BS02 UDP A 1 T155 G156 F203 W225 D227 S228 D229 K382 T40 G41 F88 W110 D112 S113 D114 K267 2.4.2.39 PYSLGPKISDWDEQRRDWLKQNPSFPNFVAPNKPRVLLVTGSAPKPCENPVGDHYLLKSIKNKIDYCRIHGIEIFYNMALLDAEMAGFWAKLPLIRKLLLSHPEIEFLWWMDSDAMFTDMVFELPWERYKDYNLVMHGWNEMVYDQKNWIGLNTGSFLLRNSQWSLDLLDAWAPMGPKGKIREEAGKVLTRELKDRPAFEADDQSAMVYLLATEREKWGGKVYLESGYYLHGYWGILVDRYEEMIENHKPGFGDHRWPLVTHFVGCKPCGKFGDYPVERCLRQMDRAFNFGDNQILQMYGFTHKSLGSRRVKPTRNQTDRPLDAKDEFGLLHPPFKA 6bsv B 2.43 BS02 UDP B 1 T155 G156 S157 G202 F203 W225 D227 S228 D229 K382 T40 G41 S42 G87 F88 W110 D112 S113 D114 K267 2.4.2.39 PYSLGPKISDWDEQRRDWLKQNPSFPNFVAPNKPRVLLVTGSAPKPCENPVGDHYLLKSIKNKIDYCRIHGIEIFYNMALLDAEMAGFWAKLPLIRKLLLSHPEIEFLWWMDSDAMFTDMVFELPWERYKDYNLVMHGWNEMVYDQKNWIGLNTGSFLLRNSQWSLDLLDAWAPMGPKGKIREEAGKVLTRELKDRPAFEADDQSAMVYLLATEREKWGGKVYLESGYYLHGYWGILVDRYEEMIENHKPGFGDHRWPLVTHFVGCKPCGKFGDYPVERCLRQMDRAFNFGDNQILQMYGFTHKSLGSRRVKPTRNQTDRPLDAKDEFGLLHPPFKA 6bsw A 2.16 BS02 UDP A 1 T155 G156 A158 G202 F203 D227 S228 D229 H377 V379 G380 K382 T40 G41 A43 G87 F88 D112 S113 D114 H262 V264 G265 K267 2.4.2.39 PYSLGPKISDWDEQRRDWLKQNPSFPNFVAPNKPRVLLVTGSAPKPCENPVGDHYLLKSIKNKIDYCRIHGIEIFYNMALLDAEMAGFWAKLPLIRKLLLSHPEIEFLWWMDSDAMFTDMVFELPWERYKDYNLVMHGWNEMVYDQKNWIGLNTGSFLLRNSQWSLDLLDAWAPMGPKGKIREEAGKVLTRELKDRPAFEADDQSAMVYLLATEREKWGGKVYLESGYYLHGYWGILVDRYEEMIENHKPGFGDHRWPLVTHFVGCKPCGKFGDYPVERCLRQMDRAFNFGDNQILQMYGFTHKSLGSRRVKPTRNQTDRPLDAKDEFGLLHPPFKA 6bsw A 2.16 BS03 CE6 A 1 F203 W254 E256 M257 W264 I265 N268 P312 F314 Q319 Y344 H346 Y348 I351 V379 G380 K382 D389 Y390 F88 W139 E141 M142 W149 I150 N153 P197 F199 Q204 Y229 H231 Y233 I236 V264 G265 K267 D274 Y275 2.4.2.39 PYSLGPKISDWDEQRRDWLKQNPSFPNFVAPNKPRVLLVTGSAPKPCENPVGDHYLLKSIKNKIDYCRIHGIEIFYNMALLDAEMAGFWAKLPLIRKLLLSHPEIEFLWWMDSDAMFTDMVFELPWERYKDYNLVMHGWNEMVYDQKNWIGLNTGSFLLRNSQWSLDLLDAWAPMGPKGKIREEAGKVLTRELKDRPAFEADDQSAMVYLLATEREKWGGKVYLESGYYLHGYWGILVDRYEEMIENHKPGFGDHRWPLVTHFVGCKPCGKFGDYPVERCLRQMDRAFNFGDNQILQMYGFTHKSLGSRRVKPTRNQTDRPLDAKDEFGLLHPPFKA 6bvg A 3.20 BS01 MAL A 1 L17 V20 E231 R232 H240 H241 T244 Y249 K307 Q310 V353 T354 E355 F393 L13 V16 E227 R228 H236 H237 T240 Y245 K303 Q306 V349 T350 E351 F389 2.7.1.69 SFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMSAGDINAVHTIARVMCDIGWAIITNLHILFAVAIGGSWAKDRAGGAFAALLAFVLTNRITGAIFGVNAEMLADSKAKVSSVLAGDLIVKDYFTSVLGAPALNMGVFVGIITGFLGATLYNKYYNYNKLPQALAFFNGKRFVPFVVIVWSTVTAIVLSLLWPFIQSGLNEFGRWIAASKDSAPIVAPFVYGTLERLLLPFGLHHMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWICDLNNLLANGDTKAYNDLLNNVVPARFKAGQVIGSTAALMGIAFAMFRNVDKEKRAKYKPMFLSAALAVFLTGVTEPIEFMFMFIAPVLYVVYAITTGLAFALADLINLRVHAFGFIELITRTPMMVNAGLTRDLINFVIVSLVFFGLNFTLFNFLIKKFNLPTPGRAGNYI 6ccz A 2.14 BS01 SEY A 1 P183 F186 P102 F105 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz A 2.14 BS02 SEY A 2 N378 Y379 N292 Y293 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz A 2.14 BS03 SEY A 3 L162 G173 V174 E341 L81 G92 V93 E255 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz A 2.14 BS04 SEY A 4 Y370 S373 P374 D375 Y284 S287 P288 D289 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz A 2.14 BS05 SEY A 5 G262 A263 Y266 R268 M288 V293 N408 G176 A177 Y180 R182 M202 V207 N322 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz A 2.14 BS06 SEY A 6 L138 P139 I155 Q158 L57 P58 I74 Q77 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz A 2.14 BS07 SEY A 7 G137 L138 N345 N346 F349 P350 G56 L57 N259 N260 F263 P264 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz A 2.14 BS08 SEY A 8 P529 I530 P531 P439 I440 P441 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz A 2.14 BS09 SEY A 9 S119 V366 Y370 S38 V280 Y284 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz B 2.14 BS02 SEY B 2 L490 S492 L399 S401 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz B 2.14 BS03 SEY B 3 Q158 G173 V174 K332 E341 Q77 G92 V93 K246 E255 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz B 2.14 BS04 SEY B 4 T462 P529 I530 P531 T371 P438 I439 P440 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz B 2.14 BS05 SEY B 5 V395 K400 L401 G404 V309 K314 L315 G318 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6ccz B 2.14 BS07 SEY B 7 G140 R142 Y144 G59 R61 Y63 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6cd1 A 1.91 BS01 PLS A 1 S114 S180 G181 S182 H209 A263 S264 D289 A291 H292 T315 H317 K318 R454 S33 S99 G100 S101 H128 A182 S183 D208 A210 H211 T234 H236 K237 R373 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6cd1 A 1.91 BS02 PLG B 1 Y134 Y144 G354 G355 Y53 Y63 G273 G274 2.1.2.1 FLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6cd1 B 1.91 BS01 PLS A 1 Y134 E136 Y144 G354 G355 Y52 E54 Y62 G272 G273 2.1.2.1 LDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6cd1 E 1.91 BS01 GLY E 1 S114 H292 K318 R454 S32 H210 K236 R372 2.1.2.1 LDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6cd1 F 1.91 BS01 GLY E 1 E136 Y144 E54 Y62 2.1.2.1 LDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGGMIFFKKDAVHGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLNKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 6cfw J 3.70 BS01 SF4 J 1 S34 C35 C38 G100 A101 C102 C132 P133 S22 C23 C26 G88 A89 C90 C120 P121 1.12.7.2 29754813 RIAQLCKFIGRSPWVFHVNSGSCNGCDIEIIAALTPRYDAERFGVKLVGSPRHADILLVTGPVTNQSLERVKLVYEQTPDPKIVIAIGACPTGGSVFYESPFTNAPLDRIIPVDVFVPGCPPRPEAILHGVVLALEKLAKMIK 6cfw L 3.70 BS01 NFU L 1 C68 C71 H75 R320 P344 T345 C374 C377 C62 C65 H69 R314 P338 T339 C368 C371 1.12.7.2 29754813 WVKIPFGPIHPGLEEPEKFIITLDGERIVNVDVKLGYNLRGVQWIGMRRNYVQIMYLAERMCGICSFSHNHTYVRAVEEMAGIEVPERAEYIRVIVGELERIHSHLLNLGVVGHDIGYDTVLHLTWLARERVMDVLEAVSGNRVNYSMVTIGGVRRDIGEKQKRLILDMIKYYREVLPQIEDVFLHDSTIEARLRDVAVVPKKLAIEMGAVGPTARGSGIKEDSRWSEQLGVYPDLGIKPVTPEDVTGEKARGDVYDRMAVRIGELWMSLDLLEHALDQMPEGKIKTFPKDNILVAKLKLLGDGEGIGRYEAPRGELVHYVRGQKGRDGPVRWKPREPTFPNLFTIAKALEGNELADLVVAIASIDPCLSCTDR 6cfw N 3.70 BS01 SF4 N 1 C56 P57 V60 C77 V78 M79 C80 K81 C83 C55 P56 V59 C76 V77 M78 C79 K80 C82 29754813 IRLPLLPTVIKNLFKKPATNPFPKTEPVPVPEDFRGKLVYNVDKCVGCRMCVTVCPAGVFVYLPEIRKVTLWIGRCVMCKQCVDVCPTAALQMSDEFLLASYDKYDAKLIYLTPEEAEDIK 6cfw N 3.70 BS02 SF4 N 2 C46 V47 G48 C49 R50 M51 C52 V70 C87 P88 L92 C45 V46 G47 C48 R49 M50 C51 V69 C86 P87 L91 29754813 IRLPLLPTVIKNLFKKPATNPFPKTEPVPVPEDFRGKLVYNVDKCVGCRMCVTVCPAGVFVYLPEIRKVTLWIGRCVMCKQCVDVCPTAALQMSDEFLLASYDKYDAKLIYLTPEEAEDIK 6cjf A 1.63 BS02 ORO A 1 K100 N145 Y147 G148 F149 N212 N284 T285 K63 N108 Y110 G111 F112 N175 N235 T236 1.3.5.2 29727569 GDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRRLEA 6cjf A 1.63 BS03 F54 A 1 Y38 M43 L46 Q47 P52 A55 H56 A59 F62 T63 V134 R136 Y356 T360 P364 Y6 M11 L14 Q15 P20 A23 H24 A27 F30 T31 V97 R99 Y307 T311 P315 1.3.5.2 29727569 GDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRRLEA 6cjf A 1.63 BS04 ZWI A 1 Y38 L42 F62 Y6 L10 F30 1.3.5.2 29727569 GDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRRLEA 6cjf B 1.63 BS04 ZWI B 1 L58 F62 L23 F27 1.3.5.2 29727569 RFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRRLEA 6cjf B 1.63 BS05 ZWI B 2 L84 G85 R241 R249 A251 D278 L42 G43 R191 R199 A201 D228 1.3.5.2 29727569 RFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRRLEA 6cjg A 2.85 BS02 F51 A 1 Y38 M43 Q47 P52 A55 H56 A59 L67 R136 Y356 T360 P364 Y5 M10 Q14 P19 A22 H23 A26 L34 R101 Y315 T319 P323 1.3.5.2 29727569 DERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHR 6cjg A 2.85 BS03 ZWI A 1 D34 Y38 F62 D1 Y5 F29 1.3.5.2 29727569 DERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHR 6cpw A 1.85 BS01 F8V A 1 I29 A33 Y34 A50 K52 I54 Y62 R65 T66 E69 Q103 D104 L105 M106 E107 T108 D109 K112 S151 N152 L154 C164 D165 G167 I12 A16 Y17 A28 K30 I32 Y40 R43 T44 E47 Q81 D82 L83 M84 E85 T86 D87 K90 S129 N130 L132 C142 D143 G145 2.7.11.24 29748051 VFDVRYTNLSYIGEGAYGMVCSAYDRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFLDDLPKEKLKELIFEETARFQPG 6cvj A 3.20 BS01 III D 1 Y262 R264 I265 D424 A426 A427 K430 D431 E434 V435 S439 Y262 R264 I265 D424 A426 A427 K430 D431 E434 V435 S439 29748322 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 6cvj B 3.20 BS02 GDP B 1 Q11 C12 Q15 N101 S140 G143 G144 T145 G146 D179 N206 Y224 N228 Q11 C12 Q15 N99 S138 G141 G142 T143 G144 D177 N204 Y222 N226 29748322 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6cvj C 3.20 BS01 III D 1 F399 R400 R401 K402 F389 R390 R391 K392 29748322 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 6cvn A 3.90 BS01 III D 1 F262 D427 S430 E431 Q434 Y435 T439 F260 D417 S420 E421 Q424 Y425 T429 29748322 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 6cvn B 3.90 BS01 III D 1 Y262 R264 D396 Y399 A400 K401 R422 E423 D424 A426 A427 K430 D431 E434 S439 Y262 R264 D396 Y399 A400 K401 R422 E423 D424 A426 A427 K430 D431 E434 S439 29748322 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 6cvn B 3.90 BS02 GTP B 1 G10 Q11 A12 Q15 A99 N101 S140 G143 G144 T145 G146 I171 T179 N206 Y224 L227 N228 G10 Q11 A12 Q15 A99 N101 S140 G143 G144 T145 G146 I171 T179 N206 Y224 L227 N228 29748322 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 6cvn C 3.90 BS01 III D 1 F399 R400 R401 K402 E422 F389 R390 R391 K392 E412 29748322 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 6czy A 1.75 BS01 PMP A 1 G144 A145 T146 F149 W171 C217 N219 T221 D241 S243 Q264 K265 G76 A77 T78 F81 W103 C149 N151 T153 D173 S175 Q196 K197 2.6.1.52 SNARVFNFAAGPATLPENVLLKAQADLYNWRGSGMSVMEMSHRGKEFLSIIQKAESDLRQLLEIPQEYSVLFLQGGATTQFAALPLNLCKSDDTVDFVVTGSWGDKAVKEAKKYCKTNVIWSGKSEKYTKVPSFEELEQTPDAKYLHICANETIHGVEFKDYPVPKNGFLVADMSSNFCSKPVDVSKFGVIYGGAQKNVGPSGVTIVIIRKDLIGNAQDITPVMLDYKIHDENSSLYNTPPCFGIYMCGLVFEDLLEQGGLKEVEKKNQRKADLLYNAIEESNGFFRCPVEKSVRSLMNVPFTLEKSELEAEFIKEAAKEKMVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQAKHA 6czy A 1.75 BS02 PMP B 1 N306 T307 N238 T239 2.6.1.52 SNARVFNFAAGPATLPENVLLKAQADLYNWRGSGMSVMEMSHRGKEFLSIIQKAESDLRQLLEIPQEYSVLFLQGGATTQFAALPLNLCKSDDTVDFVVTGSWGDKAVKEAKKYCKTNVIWSGKSEKYTKVPSFEELEQTPDAKYLHICANETIHGVEFKDYPVPKNGFLVADMSSNFCSKPVDVSKFGVIYGGAQKNVGPSGVTIVIIRKDLIGNAQDITPVMLDYKIHDENSSLYNTPPCFGIYMCGLVFEDLLEQGGLKEVEKKNQRKADLLYNAIEESNGFFRCPVEKSVRSLMNVPFTLEKSELEAEFIKEAAKEKMVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQAKHA 6czz A 1.70 BS02 SEP A 1 A78 W171 T221 I222 K265 H396 R397 R403 A8 W101 T151 I152 K195 H326 R327 R333 2.6.1.52 ARVFNFAAGPATLPENVLLKAQADLYNWRGSGMSVMEMSHRGKEFLSIIQKAESDLRQLLEIPQEYSVLFLQGGATTQFAALPLNLCKSDDTVDFVVTGSWGDKAVKEAKKYCKTNVIWSGKSEKYTKVPSFEELEQTPDAKYLHICANETIHGVEFKDYPVPKNGFLVADMSSNFCSKPVDVSKFGVIYGGAQKNVGPSGVTIVIIRKDLIGNAQDITPVMLDYKIHDENSSLYNTPPCFGIYMCGLVFEDLLEQGGLKEVEKKNQRKADLLYNAIEESNGFFRCPVEKSVRSLMNVPFTLEKSELEAEFIKEAAKEKMVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQAKHA 6czz A 1.70 BS04 SEP B 1 H110 R111 H40 R41 2.6.1.52 ARVFNFAAGPATLPENVLLKAQADLYNWRGSGMSVMEMSHRGKEFLSIIQKAESDLRQLLEIPQEYSVLFLQGGATTQFAALPLNLCKSDDTVDFVVTGSWGDKAVKEAKKYCKTNVIWSGKSEKYTKVPSFEELEQTPDAKYLHICANETIHGVEFKDYPVPKNGFLVADMSSNFCSKPVDVSKFGVIYGGAQKNVGPSGVTIVIIRKDLIGNAQDITPVMLDYKIHDENSSLYNTPPCFGIYMCGLVFEDLLEQGGLKEVEKKNQRKADLLYNAIEESNGFFRCPVEKSVRSLMNVPFTLEKSELEAEFIKEAAKEKMVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQAKHA 6d1v B 1.81 BS01 NUC C 1 R8 N10 R27 Q34 Q37 G38 G39 E53 E57 Y77 L79 L83 Q95 E120 V137 F139 K140 R9 N11 R28 Q35 Q38 G39 G40 E54 E58 Y78 L80 L84 Q96 E121 V138 F140 K141 3.6.1.- 29733359 SMIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSL 6d2l A 2.00 BS01 FTG A 1 F150 Y153 Q159 R168 G192 I197 E214 A215 G240 K241 V242 E243 E257 M259 Y261 E266 M268 S271 H414 W415 F3 Y6 Q12 R21 G45 I50 E67 A68 G93 K94 V95 E96 E110 M112 Y114 E119 M121 S124 H267 W268 2.1.1.319 QYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 6d2l C 2.00 BS01 FTG C 1 Y149 F150 Y153 Q159 M162 M163 R168 G192 C193 I197 E214 A215 G240 K241 V242 E243 E257 M259 E266 M268 S271 H414 W415 Y2 F3 Y6 Q12 M15 M16 R21 G45 C46 I50 E67 A68 G93 K94 V95 E96 E110 M112 E119 M121 S124 H267 W268 2.1.1.319 QYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 6d2l E 2.00 BS01 FTG E 1 F150 Y153 R168 G192 I197 E214 A215 G240 K241 V242 E243 E257 M259 E266 M268 S271 H414 W415 F2 Y5 R20 G44 I49 E66 A67 G92 K93 V94 E95 E109 M111 E118 M120 S123 H266 W267 2.1.1.319 YFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 6d2l F 2.00 BS01 FTG F 1 F150 F152 Y153 Q159 R168 G192 E214 A215 G240 K241 V242 E243 E257 M259 Y261 E266 M268 S271 H414 F2 F4 Y5 Q11 R20 G44 E66 A67 G92 K93 V94 E95 E109 M111 Y113 E118 M120 S123 H266 2.1.1.319 YFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRY 6d32 A 3.75 BS01 CY8 A 1 D68 L81 W82 V130 E133 R134 P137 D33 L46 W47 V95 E98 R99 P102 KCKKTTTCEPLKYNICLGSVLPYALTSTVLAEDSSSQDEVHDKLSLWSGLRNAPRCWDAIRPLLCAVYMPKCEGGKVELPSQGLCQTTRVPCAIVARERGWPDFLKCTTDYFPEGCPNEVQNIKFNSAGQCEAPLVRTDNPKSWYEDVEGCGIQCQNPLFTNKEHREMHIYIAIFSSVTIFCTFFTLATFLVDWKNSNRYPAVILFYVNACFFAGSIGWLAQFMDGARDEIVCRGDGTMRLGEPTSSETLSCVIIFIIVYYSMMSGVIWFVMLTYAWHTSFKALSGKTSYFHLITWSIPFVLTVAILAVAQVDGDSVSGICFVGYKNYHYRAGFVLAPIGLVLIGGGYFLIRGVMTLFSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLSKINETMLRLGIFGFLAFGFVLITFGCHFYDFFNQAEWERSFREYVLCEANVAIAEQTNKPIPECYIKNRPSLLVEKINLFAMFGTGISMSTWVWTKATIIIWKRAWCRI 6d32 A 3.75 BS02 CY8 A 2 N192 L194 F195 D357 Y367 K368 Q450 E454 F457 E491 N157 L159 F160 D315 Y325 K326 Q498 E502 F505 E539 KCKKTTTCEPLKYNICLGSVLPYALTSTVLAEDSSSQDEVHDKLSLWSGLRNAPRCWDAIRPLLCAVYMPKCEGGKVELPSQGLCQTTRVPCAIVARERGWPDFLKCTTDYFPEGCPNEVQNIKFNSAGQCEAPLVRTDNPKSWYEDVEGCGIQCQNPLFTNKEHREMHIYIAIFSSVTIFCTFFTLATFLVDWKNSNRYPAVILFYVNACFFAGSIGWLAQFMDGARDEIVCRGDGTMRLGEPTSSETLSCVIIFIIVYYSMMSGVIWFVMLTYAWHTSFKALSGKTSYFHLITWSIPFVLTVAILAVAQVDGDSVSGICFVGYKNYHYRAGFVLAPIGLVLIGGGYFLIRGVMTLFSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLSKINETMLRLGIFGFLAFGFVLITFGCHFYDFFNQAEWERSFREYVLCEANVAIAEQTNKPIPECYIKNRPSLLVEKINLFAMFGTGISMSTWVWTKATIIIWKRAWCRI 6d35 A 3.90 BS01 CLR A 1 D68 L81 W82 I129 E133 R134 D33 L46 W47 I94 E98 R99 KCKKTTTCEPLKYNICLGSVLPYALTSTVLAEDSSSQDEVHDKLSLWSGLRNAPRCWDAIRPLLCAVYMPKCEGGKVELPSQGLCQTTRVPCAIVARERGWPDFLKCTTDYFPEGCPNEVQNIKFNSAGQCEAPLVRTDNPKSWYEDVEGCGIQCQNPLFTNKEHREMHIYIAIFSSVTIFCTFFTLATFLVDWKNSNRYPAVILFYVNACFFAGSIGWLAQFMDGARDEIVCRGDGTMRLGEPTSSETLSCVIIFIIVYYSMMSGVIWFVMLTYAWHTSFKALSGKTSYFHLITWSIPFVLTVAILAVAQVDGDSVSGICFVGYKNYHYRAGFVLAPIGLVLIGGGYFLIRGVMTLFSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLSKINETMLRLGIFGFLAFGFVLITFGCHFYDFFNQAEWERSFREYVLCEANVAIAEQTNKPIPECYIKNRPSLLVEKINLFAMFGTGISMSTWVWTKATIIIWKRAWCRI 6d45 A 1.78 BS01 HEM A 1 K42 H43 H64 T67 E68 A71 S92 H93 H97 I99 L104 F138 K42 H43 H64 T67 E68 A71 S92 H93 H97 I99 L104 F138 VLSEGEWQLVLHVWAKVEADVAGHGQDIHIRLFKSHPETLEKHDRFKHLKTEAEMKASEDLKKHGVTELTALGAILKKKGHHEAELKPSAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG 6dcn B 2.44 BS01 III C 1 A93 E96 F97 R100 Y101 F105 L108 L112 Q125 V126 E129 L130 R132 D133 N136 G138 R139 F146 L194 Y195 A41 E44 F45 R48 Y49 F53 L56 L60 Q73 V74 E77 L78 R80 D81 N84 G86 R87 F94 L142 Y143 PLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN 6dd4 B 2.10 BS01 G6J B 1 I43 I51 V69 K71 P111 M131 D132 R133 F134 G135 L184 V196 D197 I21 I26 V41 K43 P83 M99 D100 R101 F102 G103 L152 V164 D165 2.7.11.1 FAVGEIITDMAAAAWKVGLPIGQGCIYLADMNSSGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6ddp A 1.49 BS02 G6Y A 1 I5 W6 A7 D27 Q28 F31 T46 L50 P51 V54 L57 R60 I94 Y100 I5 W6 A7 D27 Q28 F31 T46 L50 P51 V54 L57 R60 I94 Y100 1.5.1.3 MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS 6ddp D 1.49 BS02 G6Y D 1 I5 W6 A7 D19 D27 Q28 F31 R32 T46 S49 L50 V54 L57 R60 I94 Y100 I5 W6 A7 D19 D27 Q28 F31 R32 T46 S49 L50 V54 L57 R60 I94 Y100 1.5.1.3 MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS 6dds A 1.72 BS02 U75 A 1 I5 W6 A7 I20 D27 Q28 F31 R32 S49 L50 P51 V54 L57 R60 I94 Y100 I5 W6 A7 I20 D27 Q28 F31 R32 S49 L50 P51 V54 L57 R60 I94 Y100 1.5.1.3 MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS 6ddw A 1.40 BS02 G7D A 1 W6 A7 I20 D27 Q28 A29 F31 R32 L50 P51 V54 L57 R60 I94 W6 A7 I20 D27 Q28 A29 F31 R32 L50 P51 V54 L57 R60 I94 1.5.1.3 MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS 6de4 A 2.41 BS01 NDP A 1 V8 A9 I16 G17 G20 L22 G53 K54 K55 T56 S59 L75 S76 R77 E78 R91 V115 G116 G117 S118 S119 V120 Y121 E123 T146 V8 A9 I16 G17 G20 L22 G53 K54 K55 T56 S59 L75 S76 R77 E78 R91 V115 G116 G117 S118 S119 V120 Y121 E123 T146 1.5.1.3 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 6de4 A 2.41 BS02 G6Y A 1 I7 V8 A9 E30 F31 F34 T56 S59 I60 P61 N64 L67 V115 I7 V8 A9 E30 F31 F34 T56 S59 I60 P61 N64 L67 V115 1.5.1.3 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 6de4 B 2.41 BS03 CA B 1 Q84 G85 Q84 G85 1.5.1.3 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 6de5 A 2.30 BS01 NDP A 1 F45 A53 T54 G57 S59 G84 V85 G86 T87 V120 T121 R122 S123 E175 G195 P196 T197 L198 T201 R225 I227 F33 A41 T42 G45 S47 G72 V73 G74 T75 V108 T109 R110 S111 E163 G183 P184 T185 L186 T189 R213 I215 PLRLLSSVHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT 6de5 A 2.30 BS02 G8J A 1 N44 F45 I46 S59 A63 D67 R68 F71 E193 T214 N32 F33 I34 S47 A51 D55 R56 F59 E181 T202 PLRLLSSVHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT 6deb B 1.70 BS01 MTX B 1 L93 V94 Q95 L96 K104 D118 T140 I168 V169 V228 L95 V96 Q97 L98 K106 D120 T142 I170 V171 V230 1.5.1.5,3.5.4.9 NAMTLLDGKALSAKIKEELKEKNQFLKSKGIESCLAVILVGDNPASQTYVKSKAKACEECGIKSLVYHLNENITQNELLALINTLNHDDSVHGILVQLPLPDHICKDLILESIISSKDVDGFHPINVGYLNLGLESGFLPCTPLGVMKLLKAYEIDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDLSLYTRQADLIIVAAGCVNLLRSDMVKEGVIVVDVGINRLESGKIVGDVDFEEVSKKSSYITPVPGGVGPMTIAMLLENTVKSAKNRLN 6deb B 1.70 BS02 MTX B 2 Y47 K51 Q95 A208 G209 V228 Y49 K53 Q97 A210 G211 V230 1.5.1.5,3.5.4.9 NAMTLLDGKALSAKIKEELKEKNQFLKSKGIESCLAVILVGDNPASQTYVKSKAKACEECGIKSLVYHLNENITQNELLALINTLNHDDSVHGILVQLPLPDHICKDLILESIISSKDVDGFHPINVGYLNLGLESGFLPCTPLGVMKLLKAYEIDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDLSLYTRQADLIIVAAGCVNLLRSDMVKEGVIVVDVGINRLESGKIVGDVDFEEVSKKSSYITPVPGGVGPMTIAMLLENTVKSAKNRLN 6dex B 2.10 BS01 ZN B 1 C100 C102 C154 H156 C94 C96 C148 H150 NYSKLLRNLVTEDNVLNEVVVSFLYQLFPRDLFVRAFSLLESADMFIYVWMPTPKEADELLESLYNGTPLYRPIVRPRGPDDRPVCVDLDHWFCSCTEFAATCRPHLVGDTPLSDALFRPTEAADPDDCFGMLAGLQHLRADPEKLMCEHLFAFAILLQTDLRVLRHFSTGPGAQVFVLGITSIDEWLKLHLNVV 6dfu A 2.05 BS01 TRP A 1 F7 G9 V42 H45 Y128 M132 D135 I136 V144 Q150 F5 G7 V40 H43 Y126 M130 D133 I134 V142 Q148 6.1.1.2 KPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKATLDVLALYLACGIDPNKSTIFVQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAENINVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDIANRFNALYGNIFTIPEIFIGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVSTLLASLQERFHQYRNDETLLDNILRQGAEKARAKAQETLAKVYEAVGFVAAK 6f3d A 2.38 BS01 CJT A 1 M192 V200 A211 K213 Y262 V263 Y264 M265 D272 L318 S328 M29 V37 A48 K50 Y90 V91 Y92 M93 D100 L146 S156 2.7.11.1 29398441 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLALKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARAVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT 6f3e A 2.67 BS01 CJQ A 1 M192 E194 G195 V200 A211 K213 Y262 V263 M265 D272 L277 N316 L318 S328 D329 M29 E31 G32 V37 A48 K50 Y84 V85 M87 D94 L99 N138 L140 S150 D151 2.7.11.1 29398441 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLLKQQFDQEIKVMAKCQHENLVELLGFSLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLATVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT 6f3e B 2.67 BS01 CJQ B 1 M192 G193 E194 G196 V200 A211 K213 Y262 V263 M265 D272 L277 A315 L318 S328 D329 M29 G30 E31 G33 V37 A48 K50 Y93 V94 M96 D103 L108 A146 L149 S159 D160 2.7.11.1 29398441 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLTTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT 6f3g A 2.37 BS01 CJN A 1 M192 G193 V200 A211 Y262 V263 Y264 M265 D272 L318 M27 G28 V32 A43 Y87 V88 Y89 M90 D97 L143 2.7.11.1 29398441 RFHSFSFYELKNVTNNFDERPISVNKMGEGVVYKGYVNNTTVAVKKLATTEELKQQFDQEIKVMAKCQHENLVELLGFSSDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARATVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT 6f3g B 2.37 BS01 CJN B 1 M192 G193 V200 A211 V246 Y262 V263 M265 D272 L318 M29 G30 V37 A48 V76 Y89 V90 M92 D99 L145 2.7.11.1 29398441 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLTEELKQQFDQEIKVMAKCQHENLVELLGFSSDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT 6f3i A 2.14 BS01 CKN A 1 M192 V200 A211 Y262 V263 Y264 M265 D272 L277 A315 N316 L318 S328 D329 M23 V27 A36 Y71 V72 Y73 M74 D81 L86 A124 N125 L127 S137 D138 2.7.11.1 29398441 FHSFSFYELKNVTNNFDERGNKMGEVVYKGYVTTVAVKKLLKQQFDQEIKVMAKCQHENLVELLGFSCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARAVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT 6f3i B 2.14 BS01 CKN B 1 M192 G193 E194 G195 V200 A211 K213 Y262 V263 M265 D272 L277 A315 N316 L318 S328 M29 G30 E31 G32 V37 A48 K50 Y92 V93 M95 D102 L107 A145 N146 L148 S158 2.7.11.1 29398441 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMT 6fkf A 3.10 BS01 ATP A 1 R172 Q173 T174 G175 K176 T177 A178 F350 R355 Q423 Q425 R170 Q171 T172 G173 K174 T175 A176 F348 R353 Q421 Q423 3.6.3.14 29748256 TIRADEISKIIRERIEGYNREVKVVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLMIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEITASESRLIESPAPGIMSRRSVYEPLQTGLIAIDAMIPVGRGQRELIIGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSLLGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKKVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQPQSAPLTVEEQVMTIYTGTNGYLDSLELDQVRKYLVELRTYVKTNKPEFQEIISSTKTFTEEAEALLKEAIQEQMERFLLQ 6fkf A 3.10 BS02 MG A 1 T177 D262 T175 D260 3.6.3.14 29748256 TIRADEISKIIRERIEGYNREVKVVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLMIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEITASESRLIESPAPGIMSRRSVYEPLQTGLIAIDAMIPVGRGQRELIIGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSLLGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKKVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQPQSAPLTVEEQVMTIYTGTNGYLDSLELDQVRKYLVELRTYVKTNKPEFQEIISSTKTFTEEAEALLKEAIQEQMERFLLQ 6fkf D 3.10 BS01 ADP D 1 G173 G175 V176 G177 K178 T179 V180 Y362 F435 A438 F441 G157 G159 V160 G161 K162 T163 V164 Y346 F419 A422 F425 3.6.3.14 29748256 KKNLGRIAQIIGPVLDVAFPPGKMPNIYNALIVKGRDTAGQPMNVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYEIAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDSLPEQAFYLVGNIDEATAKAMNLEMES 6fkf E 3.10 BS02 ADP F 1 V364 S365 R366 V357 S358 R359 3.6.3.14 29748256 EISKIIRERIEGYNREVKVVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLMIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEITASESRLIESPAPGIMSRRSVYEPLQTGLIAIDAMIPVGRGQRELIIGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSLLGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKKVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQPQSAPLTVEEQVMTIYTGTNGYLDSLELDQVRKYLVELRTYVKTNKPEFQEIISSTKTFTEEAEALLKEAIQEQMERFLLQ 6fkf F 3.10 BS01 ADP F 1 G173 G175 G177 K178 T179 V180 Y362 F435 A438 F441 T442 G157 G159 G161 K162 T163 V164 Y346 F419 A422 F425 T426 3.6.3.14 29748256 KKNLGRIAQIIGPVLDVAFPPGKMPNIYNALIVKGRDTAGQPMNVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYEIAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDSLPEQAFYLVGNIDEATAKAMNLEMESKL 6fkf F 3.10 BS02 MG F 1 T179 E204 T163 E188 3.6.3.14 29748256 KKNLGRIAQIIGPVLDVAFPPGKMPNIYNALIVKGRDTAGQPMNVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYEIAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDSLPEQAFYLVGNIDEATAKAMNLEMESKL 6fkh E 4.20 BS02 MG E 1 T177 Q201 T171 Q195 3.6.3.14 29748256 DEISKIIRERIEGYNREVKVVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLMIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEITASESRLIESPAPGIMSRRSVYEPLQTGLIAIDAMIPVGRGQRELIIGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSLLGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKKVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQPQSAPLTVEEQVMTIYTGTNGYLDSLELDQVRKYLVELRTYVKTNKPEFQEIISSTKTFTEEAEALLKEAIQEQMERFLL 6fkh F 4.20 BS01 ADP F 1 G175 G177 K178 T179 V180 R205 Y362 F435 A438 F441 G159 G161 K162 T163 V164 R189 Y346 F419 A422 F425 3.6.3.14 29748256 KKNLGRIAQIIGPVLDVAFPPGKMPNIYNALIVKGRDTAGQPMNVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYEIAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDSLPEQAFYLVGNIDEATAKAMNLEMES 6fkh F 4.20 BS02 MG F 1 T179 R205 T163 R189 3.6.3.14 29748256 KKNLGRIAQIIGPVLDVAFPPGKMPNIYNALIVKGRDTAGQPMNVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYEIAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDSLPEQAFYLVGNIDEATAKAMNLEMES 6fkh B 4.20 BS02 MG B 1 T179 E204 R205 T163 E188 R189 3.6.3.14 29748256 KKNLGRIAQIIGPVLDVAFPPGKMPNIYNALIVKGRDTAGQPMNVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYEIAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDSLPEQAFYLVGNIDEATAKAMNLEMESKL 6fpe B 3.14 BS01 APC D 1 K166 A210 K213 Y218 K149 A193 K196 Y201 2.3.1.234 29741707 MRVLGIETSCDETAVAVLDDGKNVVVNFTVSRHHLKNLPILLKKAFEKVPPETVDVVAATYGPGLIGALLVGLSAAKGLAISLEKPFVGVNHVEAHVQAVFLANPDLKPPLVVLMVSGGHTQLMKVDEDYSMEVLGETLDDSAGEAFDKVARLLGLGYPGGPVIDRVAKKGDPEKYSFPRPMLDDDSYNFSFAGLKTSVLYFLQREKGYKVEDVAASFQKAVVDILVEKTFRLARNLGIRKIAFVGGVAANSMLREEVRKRAERWNYEVFFPPLELCTDNALMVAKAGYEKAKRGMFSPLSLNADPNL 6fpe E 3.14 BS01 MG E 1 T42 S61 E108 T42 S61 E108 29741707 MRHLRFENLTEEQLKRLAKILTENLKGGEVVILSGNLGAGKTTFVKGMIRAIGLDEKMVKSPTFTLMNVYPGLKTIYHLDLYRLQDTDFLSLDVEDILEDEDGIMVVEWGDLFDGFWPEDSIKVKIEIADESHRNVEILIPEEVNFLVEKIERYRKE 6fpe E 3.14 BS02 APC E 1 L9 T10 E11 L14 L37 G38 A39 G40 K41 T42 T43 E108 W109 S132 H133 R134 L9 T10 E11 L14 L37 G38 A39 G40 K41 T42 T43 E108 W109 S132 H133 R134 29741707 MRHLRFENLTEEQLKRLAKILTENLKGGEVVILSGNLGAGKTTFVKGMIRAIGLDEKMVKSPTFTLMNVYPGLKTIYHLDLYRLQDTDFLSLDVEDILEDEDGIMVVEWGDLFDGFWPEDSIKVKIEIADESHRNVEILIPEEVNFLVEKIERYRKE 6fpe G 3.14 BS01 APC E 1 K166 A210 K213 T214 K150 A194 K197 T198 2.3.1.234 29741707 MRVLGIETSCDETAVAVLDDGKNVVVNFTVSARHHLKNLPILLKKAFEKVPPETVDVVAATYGPGLIGALLVGLSAAKGLAISLEKPFVGVNHVEAHVQAVFLANPDLKPPLVVLMVSGGHTQLMKVDEDYSMEVLGETLDDSAGEAFDKVARLLGLGYPGGPVIDRVAKKGDPEKYSFPRPMLDDDSYNFSFAGLKTSVLYFLQREKGYKVEDVAASFQKAVVDILVEKTFRLARNLGIRKIAFVGGVAANSMLREEVRKRAERWNYEVFFPPLELCTDNALMVAKAGYEKAKRGMFSPLSLNADPNL 6fpe D 3.14 BS01 MG D 1 T42 S61 T63 D80 E108 T42 S61 T63 D80 E108 29741707 MRHLRFENLTEEQLKRLAKILTENLKGGEVVILSGNLGAGKTTFVKGMIRAIGLDEKMVKSPTFTLMNVYPGLKTIYHLDLYRLQDTDFLSLDVEDILEDEDGIMVVEWGDLFDGFWPEDSIKVKIEIADESHRNVEILIPEEVNFLVEKIERYRKE 6fpe D 3.14 BS02 APC D 1 T10 E11 L37 G38 A39 G40 K41 T42 T43 E108 W109 E131 S132 H133 R134 T10 E11 L37 G38 A39 G40 K41 T42 T43 E108 W109 E131 S132 H133 R134 29741707 MRHLRFENLTEEQLKRLAKILTENLKGGEVVILSGNLGAGKTTFVKGMIRAIGLDEKMVKSPTFTLMNVYPGLKTIYHLDLYRLQDTDFLSLDVEDILEDEDGIMVVEWGDLFDGFWPEDSIKVKIEIADESHRNVEILIPEEVNFLVEKIERYRKE 6fsh A 2.50 BS01 HEM A 1 L88 M89 H96 R100 L152 L155 A236 G237 N240 V241 M244 P283 P286 T287 R289 L312 A339 F340 G341 H345 C347 G349 T353 L68 M69 H76 R80 L132 L135 A216 G217 N220 V221 M224 P263 P266 T267 R269 L292 A319 F320 G321 H325 C327 G329 T333 29751197 PPIHTRRQGFDPADELRAAGTLTKISIETTWLAAGHAVVRQVLGDHQQFSTRRRGKGIFRPRELVGNLMDYDPPEHTRLRHLLTPGFTQRRMRRLAPRIEEIVTDRLDAMEQAGPPADLIELFADEVPGAVLCELIGVPRDDRDMFMKLCHGHLDASLSQKRRAALGDKFSRYLLAMIARERKDPGDGFIGSIVAEHGDTITDEELRGVCVQLMLAGDDNVSGMIGLGVLALLRHPEQIAALRGDDQSADRAVDELIRYLTVPYAPTPRTAVEDVMVADQVIKEGETVLCSLPMANRDRALLPDADRLDVTRTPVPHVAFGHGIHHCLGAALTRLQLRIAYTALWRRFPALQLADPAQEIMFRTSTPAYGLTSLLVAW 6ftp A 1.80 BS01 DM2 B 1 Y245 L273 S274 F277 E278 L280 Y220 L248 S249 F252 E253 L255 29760101 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKFEMPFDPQDTHQSRFYLSKKKYVMVPMMSLHHLTIPYFRDEELSCTVVQLNYTGNASALFILPDQDKMEEVEAMLSQETLSRFFESLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTERSAATALEVLFQ 6fx0 A 1.90 BS01 E9T A 1 F201 W227 F230 A234 C237 L268 L271 M272 I275 R278 F288 S289 F304 G393 L400 I412 F22 W48 F51 A55 C58 L89 L92 M93 I96 R99 F109 S110 F125 G214 L221 I233 29706423 YELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLE 6g0w A 2.34 BS01 EGW A 1 H1682 G1683 A1706 Y1714 A1716 S1722 Y1727 G1751 H1753 T1774 D1775 L1782 H70 G71 A92 Y98 A100 S106 Y111 G135 H137 T158 D159 L166 2.4.2.30 29748053 KQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRAGKNAVGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK 6g0w B 2.34 BS01 EGW B 1 H1682 G1683 Y1714 A1716 Y1721 S1722 Y1727 N1752 H1753 L1782 H70 G71 Y95 A97 Y102 S103 Y108 N133 H134 L163 2.4.2.30 29748053 KQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSKNAKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK 6g21 A 2.10 BS01 CA A 1 D238 D241 A243 D245 I247 D235 D238 A240 D242 I244 3.1.1.73 TFQGKCTGFADKINLPNVRVNFVNYVPGGTNLSLPDNPTSCGTTSQVVSEDVCRIAMAVATSNSSEITLEAWLPQNYTGRFLSTGNGGLSGCIQYYDLAYTSGLGFATVGANSGHNGTSGEPFYHHPEVLEDFVHRSVHTGVVVGKQLTKLFYEEGFKKSYYLGCSTGGRQGFKSVQKYPNDFDGVVAGAPAFNMINLMSWSAHFYSITGPVGSDTYLSPDLWNITHKEILRQCDGIDGAEDGIIEDPSLCSPVLEAIICKPGQNTTECLTGKQAHTVREIFSPLYGVNGTLLYPRMQPGSEVMASSIMYNGQPFQYSADWYRYVVYENPNWDATKFSVRDAAVALKQNPFNLQTWDADISSFRKAGGKVLTYHGLMDQLISSENSKLYYARVAETMNVPPEELDEFYRFFQISGMAHCSGGDGAYGIGNQLVTYNDANPENNVLMAMVQWVEKGIAPETIRGAKFTNGTGSAVEYTRKHCRYPRRNVYKGPGNYTDENAWQCV 6g21 B 2.10 BS01 FER B 1 W359 R395 W356 R392 3.1.1.73 TFQGKCTGFADKINLPNVRVNFVNYVPGGTNLSLPDNPTSCGTTSQVVSEDVCRIAMAVATSNSSEITLEAWLPQNYTGRFLSTGNGGLSGCIQYYDLAYTSGLGFATVGANSGHNGTSGEPFYHHPEVLEDFVHRSVHTGVVVGKQLTKLFYEEGFKKSYYLGCSTGGRQGFKSVQKYPNDFDGVVAGAPAFNMINLMSWSAHFYSITGPVGSDTYLSPDLWNITHKEILRQCDGIDGAEDGIIEDPSLCSPVLEAIICKPGQNTTECLTGKQAHTVREIFSPLYGVNGTLLYPRMQPGSEVMASSIMYNGQPFQYSADWYRYVVYENPNWDATKFSVRDAAVALKQNPFNLQTWDADISSFRKAGGKVLTYHGLMDQLISSENSKLYYARVAETMNVPPEELDEFYRFFQISGMAHCSGGDGAYGIGNQLVTYNDANPENNVLMAMVQWVEKGIAPETIRGAKFTNGTGSAVEYTRKHCRYPRRNVYKGPGNYTDENAWQCV 6g95 A 2.31 BS01 RTZ B 1 G36 V37 I38 L43 L184 I185 L186 G5 V6 I7 L12 L153 I154 L155 29741894 SIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQASGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTEWAFWETSEELSFTVVGGGGGGG 6g95 B 2.31 BS01 RTZ B 1 M548 H549 L554 I555 M47 H48 L53 I54 29741894 EAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPADWTKNITDKIDQIIHDFV 6g9b A 2.26 BS01 IXX A 1 I38 L43 L184 I185 L186 I8 L13 L154 I155 L156 29741894 RSIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQASGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTWAFWETLSFTVVSGGGGGGG 6g9b B 2.26 BS01 IXX A 1 L515 M548 L14 M45 29741894 EAIVNAQPKCNPNLHYWTTQGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPADWTKNITDKIDQIIHDFV 6g9i A 2.19 BS01 CXX B 1 I38 L184 L186 I7 L153 L155 29741894 SIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQASGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTEWAFWETLSFTVVGGGGGGG 6g9i B 2.19 BS01 CXX B 1 M548 L558 M47 L57 29741894 EAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPADWTKNITDKIDQIIHDFV 6gg4 A 2.46 BS01 PHE A 1 R43 N44 N70 R106 H464 G468 I469 F470 F502 R21 N22 N48 R84 H442 G446 I447 F448 F480 2.7.1.40 29748232 ADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gg4 B 2.46 BS01 PHE B 1 R43 N44 N70 R106 H464 G468 I469 F470 P471 R21 N22 N48 R84 H442 G446 I447 F448 P449 2.7.1.40 29748232 ADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gg4 C 2.46 BS01 PHE C 1 R43 N44 N70 R106 H464 G468 I469 F470 P471 R21 N22 N48 R84 H343 G347 I348 F349 P350 2.7.1.40 29748232 ADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPELPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gg4 D 2.46 BS01 PHE D 1 R43 N44 N70 R106 H464 G468 I469 F470 R21 N22 N48 R84 H343 G347 I348 F349 2.7.1.40 29748232 ADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPELPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gg5 A 3.20 BS01 TRP A 1 R43 N44 N70 R106 H464 G468 I469 F470 P471 F502 R21 N22 N48 R84 H442 G446 I447 F448 P449 F480 2.7.1.40 29748232 ADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gg5 C 3.20 BS01 TRP C 1 R43 N44 N70 R106 H464 G468 I469 F470 P471 F502 R21 N22 N48 R84 H343 G347 I348 F349 P350 F381 2.7.1.40 29748232 ADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPELPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gg6 B 2.96 BS01 MG B 1 K270 E272 A293 D296 T328 K249 E251 A272 D275 T307 2.7.1.40 29748232 MADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gg6 C 2.96 BS01 MG C 1 E272 A293 D296 E251 A272 D275 2.7.1.40 29748232 MADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gg6 D 2.96 BS01 MG D 1 K270 E272 A293 D296 K249 E251 A272 D275 2.7.1.40 29748232 MADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gg6 H 2.96 BS02 SER H 1 R43 N44 N70 R106 H464 I469 F470 R22 N23 N49 R85 H443 I448 F449 2.7.1.40 29748232 MADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 6gi6 A 1.98 BS01 EZB A 1 V214 V222 A233 K235 L263 L281 T283 Y285 H286 N341 L343 A353 V13 V21 A32 K34 L62 L80 T82 Y84 H85 N140 L142 A152 2.7.11.30 RTVARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID 6gih A 1.96 BS01 EZN A 1 Q36 Y39 L41 V67 I69 D103 S106 T108 P109 A110 Q34 Y37 L39 V65 I67 D101 S104 T106 P107 A108 2.7.11.1 29759799 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 6gin A 2.20 BS01 IR2 A 1 V214 V222 A233 K235 L263 T283 H284 Y285 H286 G289 D293 K340 N341 L343 A353 D354 V11 V19 A30 K32 L60 T80 H81 Y82 H83 G86 D90 K137 N138 L140 A150 D151 2.7.11.30 VARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID 6gip A 2.17 BS01 EUN A 1 V214 V222 A233 V234 K235 L263 L281 T283 Y285 H286 G289 L343 A353 V11 V19 A30 V31 K32 L60 L78 T80 Y82 H83 G86 L140 A150 2.7.11.30 VARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID