5mns A 2.62 BS01 HEM A 1 V93 L94 H101 R105 F112 I157 A244 G245 T248 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L366 V81 L82 H89 R93 F100 I145 A232 G233 T236 Q240 L278 R286 F309 A336 F337 G338 H342 C344 I345 G346 L354 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mns A 2.62 BS02 DEB A 1 F84 L94 L179 A244 T248 V291 S295 F296 L396 I397 F72 L82 L167 A232 T236 V279 S283 F284 L384 I385 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mns B 2.62 BS02 DEB B 1 M83 F84 L94 L179 I243 A244 T248 V291 S295 L396 M71 F72 L82 L167 I231 A232 T236 V279 S283 L384 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mns C 2.62 BS02 DEB C 1 M83 F84 L94 L179 I243 A244 T248 S295 F296 L396 I397 M71 F72 L82 L167 I231 A232 T236 S283 F284 L384 I385 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mns D 2.62 BS02 DEB D 1 F84 L94 M178 L179 I243 A244 T248 V291 F296 L396 I397 F72 L82 M166 L167 I231 A232 T236 V279 F284 L384 I385 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mns E 2.62 BS01 HEM E 1 V93 L94 H101 R105 I157 A244 G245 T248 S249 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 G362 V81 L82 H89 R93 I145 A232 G233 T236 S237 L278 R286 F309 A336 F337 G338 H342 C344 I345 G346 G350 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mns E 2.62 BS02 DEB E 1 F84 L94 L179 I243 A244 T248 V291 S295 F296 I397 F72 L82 L167 I231 A232 T236 V279 S283 F284 I385 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mns F 2.62 BS01 HEM F 1 V93 L94 H101 R105 F112 A244 G245 T248 Q252 L285 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L361 G362 L366 V81 L82 H89 R93 F100 A232 G233 T236 Q240 L271 L276 R284 F307 A334 F335 G336 H340 C342 I343 G344 L347 G348 L352 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVAALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mns F 2.62 BS02 DEB F 1 M83 F84 L94 I243 A244 T248 F296 M71 F72 L82 I231 A232 T236 F282 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVAALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv A 2.97 BS01 HEM A 1 V93 L94 H101 R105 L241 A244 G245 T248 S249 Q252 L290 F296 R298 A348 F349 G350 H354 C356 I357 G358 L361 V83 L84 H91 R95 L231 A234 G235 T238 S239 Q242 L280 F286 R288 A338 F339 G340 H344 C346 I347 G348 L351 Q59819 ADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv A 2.97 BS02 DEB A 1 M83 F84 I243 A244 V291 G294 L396 I397 M73 F74 I233 A234 V281 G284 L386 I387 Q59819 ADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv B 2.97 BS01 HEM B 1 L94 H101 R105 F112 A244 G245 T248 L285 L290 R298 A348 F349 G350 H354 C356 G358 G362 L81 H88 R92 F99 A231 G232 T235 L272 L277 R285 A335 F336 G337 H341 C343 G345 G349 Q59819 VPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv B 2.97 BS02 DEB B 1 F84 L94 S240 I243 A244 T248 S295 F296 F71 L81 S227 I230 A231 T235 S282 F283 Q59819 VPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv C 2.97 BS01 HEM C 1 L94 H101 R105 F112 A244 G245 T248 Q252 L285 L290 R298 F321 A348 F349 G350 H354 C356 G358 L366 L83 H90 R94 F101 A233 G234 T237 Q241 L274 L279 R287 F310 A337 F338 G339 H343 C345 G347 L355 Q59819 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv C 2.97 BS02 DEB C 1 M83 F84 L94 S240 I243 A244 T248 S295 F296 L396 M72 F73 L83 S229 I232 A233 T237 S284 F285 L385 Q59819 DAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv D 2.97 BS02 DEB D 1 M83 F84 L94 I243 A244 E247 T248 G294 L396 I397 M70 F71 L81 I230 A231 E234 T235 G281 L383 I384 Q59819 VPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv E 2.97 BS01 HEM E 1 V93 L94 H101 R105 L241 A244 G245 T248 Q252 L290 R298 F321 A348 F349 A353 H354 C356 I357 L361 L366 V81 L82 H89 R93 L224 A227 G228 T231 Q235 L273 R281 F304 A331 F332 A336 H337 C339 I340 L344 L349 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv E 2.97 BS02 DEB E 1 F84 L94 A244 V291 S295 L396 I397 F72 L82 A227 V274 S278 L379 I380 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv F 2.97 BS02 DEB F 1 M83 F84 I243 A244 G294 L396 I397 M71 F72 I231 A232 G282 L384 I385 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv G 2.97 BS01 HEM G 1 V93 L94 H101 R105 L241 A244 G245 T248 Q252 L285 L290 R298 F321 A348 F349 G350 A353 H354 H355 C356 I357 L366 V81 L82 H89 R93 L214 A217 G218 T221 Q225 L258 L263 R271 F294 A321 F322 G323 A326 H327 H328 C329 I330 L339 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv G 2.97 BS02 DEB G 1 M83 F84 L94 I243 A244 V291 G294 S295 F296 M71 F72 L82 I216 A217 V264 G267 S268 F269 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv H 2.97 BS01 HEM H 1 V93 L94 H101 R105 L241 A244 G245 T248 S249 Q252 L290 R298 F321 A348 F349 G350 H354 C356 I357 G358 L361 E365 V81 L82 H89 R93 L229 A232 G233 T236 S237 Q240 L278 R286 F309 A336 F337 G338 H342 C344 I345 G346 L349 E353 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv H 2.97 BS02 DEB H 1 F84 I243 A244 V291 S295 L396 I397 F72 I231 A232 V279 S283 L384 I385 Q59819 AVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSDARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv I 2.97 BS01 HEM I 1 V93 L94 H101 R105 S240 L241 A244 G245 T248 L285 H354 C356 I357 L361 V32 L33 H40 R44 S170 L171 A174 G175 T178 L211 H233 C235 I236 L240 Q59819 HYAELRRDEPVSRVTRMSDARIVLGRMFPTPVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPAAVEEMLRYTPLVSDEEVFDHADELDGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5mnv I 2.97 BS02 DEB I 1 F84 L94 L179 S240 A244 T248 L396 F28 L33 L118 S170 A174 T178 L275 Q59819 HYAELRRDEPVSRVTRMSDARIVLGRMFPTPVLAQDPPDHTRLRRLVGKAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICELLGVPLEDRDLFRTFSDAMLSAEIQRVQQDFMVYMDGLVAQRRDAPTEDLLGALALATDNDTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYESLVADPAAVEEMLRYTPLVSDEEVFDHADELDGAHHCIGAQLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 5msz A 1.10 BS01 CU1 A 1 H1 H91 Y184 H1 H91 Y184 HGHLSVPPMRSSMWRDGYNVPPNYNDDGLNCGSFDVQWVKNGGKCGECGDDYSLPRPRPNESGGMYGKNIIVANYQQGSTISVDLHIQAPHIGFFEFRLCARNDPNVLETQDCFDQHLLELADGSGTRFTMEEHVAGEYTVDLKLPQGVTCTNCVLQWFWRTGNRYGDCGDGTSGMGCGPQEEYRNCADIAIAWS 5mvo A 2.67 BS01 HEC A 1 F47 F53 A58 C59 C62 H63 Y72 R73 L77 S87 R93 R110 M230 P232 F47 F53 A58 C59 C62 H63 Y72 R73 L77 S87 R93 R110 M222 P224 A3DTD8 22949206 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mvo A 2.67 BS02 HEC A 2 N114 M116 P117 L118 F162 H168 C169 C172 H173 H183 V210 K220 L225 R240 N114 M116 P117 L118 F156 H162 C163 C166 H167 H177 V202 K212 L217 R232 A3DTD8 22949206 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mvo A 2.67 BS03 HEC C 1 S6 Y9 L10 I31 S6 Y9 L10 I31 A3DTD8 22949206 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mvo B 2.67 BS01 HEC A 1 S6 I31 S6 I31 A3DTD8 22949206 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mvo B 2.67 BS02 HEC B 1 F53 P57 A58 C59 C62 H63 Y72 R73 L77 S87 R93 I106 I107 R110 M230 P231 P232 F53 P57 A58 C59 C62 H63 Y72 R73 L77 S87 R93 I106 I107 R110 M230 P231 P232 A3DTD8 22949206 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mvo C 2.67 BS02 HEC C 1 F53 P57 C59 C62 H63 Y72 R73 L77 S87 R93 I106 R110 L111 M230 P231 P232 F53 P57 C59 C62 H63 Y72 R73 L77 S87 R93 I106 R110 L111 M230 P231 P232 A3DTD8 22949206 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mvo C 2.67 BS03 HEC C 2 N114 M116 P117 L118 F162 H168 C169 C172 H173 F182 H183 A197 V210 K220 H224 L225 R240 N114 M116 P117 L118 F162 H168 C169 C172 H173 F182 H183 A197 V210 K220 H224 L225 R240 A3DTD8 22949206 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mwa A 1.55 BS01 MG A 1 D9 D11 D185 D14 D16 D171 3.3.2.10,3.1.3.76 P34913 NLYFQGTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLN 5mwa A 1.55 BS02 8S9 A 1 D11 P17 V19 F20 F41 T50 L53 M54 L60 W63 F92 A95 I96 R99 N124 W126 I186 N189 D16 P22 V24 F25 F46 T55 L58 M59 L65 W68 F86 A89 I90 R93 N118 W120 I172 N175 3.3.2.10,3.1.3.76 P34913 NLYFQGTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLN 5mwx A 1.29 BS01 WYD A 1 S29 H44 N46 R48 H52 N61 E71 R73 D123 G124 D125 S28 H43 N45 R47 H51 N60 E70 R72 D122 G123 D124 P09382 CGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD 5mwx B 1.29 BS01 WYD B 1 V31 H44 N46 R48 H52 N61 E71 R73 D123 G124 V30 H43 N45 R47 H51 N60 E70 R72 D122 G123 P09382 CGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD 5mxq A 2.00 BS03 U8K A 1 F62 Y67 W87 D118 H179 C198 R205 G209 N210 H240 F31 Y36 W56 D87 H148 C167 R174 G178 N179 H209 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 5mzq A 2.80 BS02 MBR A 1 P120 I201 I202 W205 T255 P116 I197 I198 W201 T251 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPWLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mzq A 2.80 BS03 2IL E 1 F267 T274 V275 Y278 F263 T270 V271 Y274 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPWLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mzq B 2.80 BS03 MBR B 1 P120 I202 Y254 T255 I258 P116 I198 Y250 T251 I254 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPWLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mzq C 2.80 BS03 MBR C 1 P120 I201 I202 Y254 T255 I258 P116 I197 I198 Y250 T251 I254 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPWLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mzq D 2.80 BS03 MBR D 1 P120 I202 W205 Y254 T255 I258 P116 I198 W201 Y250 T251 I254 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPWLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5n19 A 1.62 BS01 D03 A 1 T25 H41 C44 M49 F140 N142 G143 S144 C145 H163 H164 M165 E166 H172 D187 R188 T25 H41 C44 M49 F140 N142 G143 S144 C145 H163 H164 M165 E166 H172 D187 R188 P0C6X7 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ 5n1d A 1.61 BS01 III B 1 E127 F129 S130 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 Y204 L205 E230 Y235 P236 F239 A240 D241 P243 I246 Y247 D328 E128 F130 S131 R134 K169 P170 E171 F188 L199 C200 G201 T202 P203 E204 Y205 L206 E231 Y236 P237 F240 A241 D242 P244 I247 Y248 D329 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1d A 1.61 BS02 MPD A 1 V15 F18 F100 L152 E155 K292 Y306 V18 F21 F101 L153 E156 K293 Y307 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1d A 1.61 BS03 MPD A 2 G136 R137 A233 G234 G137 R138 A234 G235 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1d A 1.61 BS04 8FZ A 1 L49 G50 V57 A70 M120 E121 V123 E170 L173 T183 D184 F327 L50 G51 V58 A71 M121 E122 V124 E171 L174 T184 D185 F328 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1f A 1.12 BS01 8ET A 1 L49 V57 A70 K72 V104 M120 E121 Y122 V123 L173 T183 D184 F327 L39 V47 A60 K62 V94 M110 E111 Y112 V113 L163 T173 D174 F317 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1g A 1.14 BS01 8G5 A 1 S14 V15 F18 L19 F100 L152 E155 K292 W302 I303 Y306 S4 V5 F8 L9 F90 L142 E145 K282 W292 I293 Y296 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1h A 1.18 BS01 MPD A 1 V15 F18 L152 E155 Y306 V5 F8 L142 E145 Y296 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1h A 1.18 BS02 MPD A 2 L89 N90 R93 E349 L79 N80 R83 E339 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1k A 1.80 BS01 III B 1 F54 Q84 H87 E127 F129 S130 R133 D166 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 E230 F239 A240 D241 D328 Y330 F49 Q78 H81 E121 F123 S124 R127 D160 K162 P163 E164 F181 L192 C193 G194 T195 P196 E197 E224 F233 A234 D235 D322 Y324 2.7.11.11 P25321 GHAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKTGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1k A 1.80 BS02 489 A 1 L49 V57 A70 E127 E170 L173 D184 F327 L44 V52 A64 E121 E164 L167 D178 F321 2.7.11.11 P25321 GHAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKTGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1k A 1.80 BS03 489 A 2 V15 F18 L152 E155 K292 I303 V12 F15 L146 E149 K286 I297 2.7.11.11 P25321 GHAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKTGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1l A 1.49 BS01 III B 1 E127 F129 S130 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 Y204 L205 E230 P236 F239 A240 D241 Y247 D328 Y330 E128 F130 S131 R134 K169 P170 E171 F188 L199 C200 G201 T202 P203 E204 Y205 L206 E231 P237 F240 A241 D242 Y248 D329 Y331 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1l A 1.49 BS02 47V A 1 G50 T51 V57 A70 K72 M120 E121 Y122 V123 L173 T183 D184 F327 G51 T52 V58 A71 K73 M121 E122 Y123 V124 L174 T184 D185 F328 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1l A 1.49 BS03 MPD A 1 V15 F18 L152 E155 K292 I303 Y306 V18 F21 L153 E156 K293 I304 Y307 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1l A 1.49 BS04 MPD A 2 N216 L277 T278 N283 N217 L278 T279 N284 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1m A 1.44 BS02 BJK A 1 V57 A70 V104 M120 E121 E127 E170 L173 T183 V58 A71 V105 M121 E122 E128 E171 L174 T184 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1n A 1.41 BS01 III B 1 K83 Q84 E127 F129 S130 R133 K168 P169 E170 F187 T197 L198 C199 G200 T201 P202 E203 Y204 E230 P236 F239 A240 D241 P243 D328 Y330 K85 Q86 E129 F131 S132 R135 K170 P171 E172 F189 T199 L200 C201 G202 T203 P204 E205 Y206 E232 P238 F241 A242 D243 P245 D330 Y332 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1n A 1.41 BS02 8G8 A 1 H131 I135 F138 H142 F314 H133 I137 F140 H144 F316 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1o A 1.80 BS02 8GB A 1 L49 V57 A70 V104 M120 E121 V123 E127 L173 T183 F327 L39 V47 A60 V94 M110 E111 V113 E117 L163 T173 F317 2.7.11.11 P25321 KKGSEQESVKEFLAKAKEEFLKKWESTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1t A 2.60 BS01 FAD A 1 I39 G40 G42 F43 G44 N65 P66 Y70 C73 P74 W108 V109 S135 P136 G137 W160 R192 C193 I288 G320 D321 K330 A331 G332 F333 A335 Y365 W415 I7 G8 G10 F11 G12 N33 P34 Y38 C41 P42 W76 V77 S103 P104 G105 W128 R160 C161 I256 G288 D289 K298 A299 G300 F301 A303 Y333 W383 W0DP88 AQRVVVIGGGFGGSTCARYLRHFDPDLEVTLINPSDTYTTCPFSNLVLGGERDLASITHDLSQLEHHHGVRLVQRWVESIDADGHRVVLDDGSAIGYDRLVVSPGIDLRWDAVEGYDQAAQEAMPHAWRPGEQTLLLRRQLEAMSDGGVVVIAPPANPFRCPPGPYERASLIAHYLKHHKPRSKILILDAKDAFAKQGLFQTGWETLYPGMIEWVPGIEGGTVERVDAATGEVFTPSGRYRGDVVNLIPPQHAGAIARNTGLTDDSGWCPVNQQTFESLQIPHIHVIGDASIAGAMPKAGFAANSQAKVCAAAVVAALHGFDPTEPSWSSTCYSLVGPEYGISVSAVYRLDNGSIVASEGAGVSPGEADDHFRQLEAVYARGWYDNITAEMYG 5n1t A 2.60 BS02 HEC B 1 F333 T363 Y411 F301 T331 Y379 W0DP88 AQRVVVIGGGFGGSTCARYLRHFDPDLEVTLINPSDTYTTCPFSNLVLGGERDLASITHDLSQLEHHHGVRLVQRWVESIDADGHRVVLDDGSAIGYDRLVVSPGIDLRWDAVEGYDQAAQEAMPHAWRPGEQTLLLRRQLEAMSDGGVVVIAPPANPFRCPPGPYERASLIAHYLKHHKPRSKILILDAKDAFAKQGLFQTGWETLYPGMIEWVPGIEGGTVERVDAATGEVFTPSGRYRGDVVNLIPPQHAGAIARNTGLTDDSGWCPVNQQTFESLQIPHIHVIGDASIAGAMPKAGFAANSQAKVCAAAVVAALHGFDPTEPSWSSTCYSLVGPEYGISVSAVYRLDNGSIVASEGAGVSPGEADDHFRQLEAVYARGWYDNITAEMYG 5n1t B 2.60 BS01 HEC B 1 C11 C14 H15 I25 P26 L28 I36 T39 M40 F43 R48 S50 T51 V52 M53 Q56 Y60 I68 I72 C11 C14 H15 I25 P26 L28 I36 T39 M40 F43 R48 S50 T51 V52 M53 Q56 Y60 I68 I72 W0DKT4 DLRGALLAGNCYGCHGPNGDSQGGIPSLSGLDADQIAETMLAFRSGTRESTVMQRQASGYSEDEIASIAQHIAQH 5n1t W 2.60 BS01 CU W 1 H1 D110 H112 H1 D109 H111 W0DSL1 HAHLRAADPPEAIVDAAGLREIRLVFSEPVVDRFSTFRAFRLSLPENGIRNLTQLNTLASELGVDTEESAHHEVELESDLSQSAEVTLHSDEPLPAGAYAVVWRVLSVDGHTTTGFHAFVHAGG 5n2l A 1.89 BS01 8J2 A 1 W370 P371 F372 V376 L383 C425 N429 H433 D434 V435 W25 P26 F27 V31 L38 C80 N84 H88 D89 V90 P25440 LSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 5n2l B 1.89 BS01 8J2 B 1 W370 P371 F372 L381 L383 C425 N429 H433 V435 M438 W25 P26 F27 L36 L38 C80 N84 H88 V90 M93 P25440 LSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 5n2l C 1.89 BS02 8J2 C 2 K363 Y373 K16 Y26 P25440 EQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 5n2m A 1.54 BS01 8J2 A 1 W81 P82 F83 K91 L92 L94 Y97 N140 D145 I146 M149 W40 P41 F42 K50 L51 L53 Y56 N99 D104 I105 M108 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 5n32 A 1.83 BS01 III B 1 K83 H87 E127 F129 S130 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 Y204 L205 I209 I210 E230 P236 F239 A240 D241 Y247 D328 Y330 K81 H85 E125 F127 S128 R131 K166 P167 E168 F185 L196 C197 G198 T199 P200 E201 Y202 L203 I207 I208 E228 P234 F237 A238 D239 Y245 D326 Y328 2.7.11.11 P25321 HMGAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n32 A 1.83 BS02 8K5 A 1 L49 V57 A70 E121 V123 E127 E170 N171 L173 T183 F327 L48 V55 A68 E119 V121 E125 E168 N169 L171 T181 F325 2.7.11.11 P25321 HMGAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n32 A 1.83 BS03 8K5 A 2 L82 K83 E86 T197 L80 K81 E84 T195 2.7.11.11 P25321 HMGAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n33 A 1.43 BS01 III B 1 S53 Q84 E127 F129 S130 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 Y204 L205 I209 I210 E230 P236 F239 A240 D241 P243 Y247 D328 Y330 S54 Q85 E128 F130 S131 R134 K169 P170 E171 F188 L199 C200 G201 T202 P203 E204 Y205 L206 I210 I211 E231 P237 F240 A241 D242 P244 Y248 D329 Y331 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n33 A 1.43 BS02 8JW A 1 V57 A70 V104 M120 E121 Y122 V123 L173 T183 F327 V58 A71 V105 M121 E122 Y123 V124 L174 T184 F328 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n36 A 1.58 BS01 III B 1 Q84 H87 E127 F129 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 E230 F239 A240 D241 D328 Y330 Q85 H88 E128 F130 R134 K169 P170 E171 F188 L199 C200 G201 T202 P203 E204 E231 F240 A241 D242 D329 Y331 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n36 A 1.58 BS02 F05 A 1 V57 M120 E127 E170 N171 L173 T183 D184 V58 M121 E128 E171 N172 L174 T184 D185 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n37 A 1.59 BS01 III B 1 F54 Q84 H87 E127 F129 S130 R133 D166 K168 P169 E170 F187 T197 L198 C199 G200 T201 P202 E203 Y204 L205 E230 P236 F239 A240 D241 Y247 D328 Y330 F55 Q85 H88 E128 F130 S131 R134 D167 K169 P170 E171 F188 T198 L199 C200 G201 T202 P203 E204 Y205 L206 E231 P237 F240 A241 D242 Y248 D329 Y331 2.7.11.11 P25321 GHMGAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n37 A 1.59 BS02 8JT A 1 L49 G50 T51 G52 G55 R56 V57 K72 L74 E127 L173 T183 D184 L50 G51 T52 G53 G56 R57 V58 K73 L75 E128 L174 T184 D185 2.7.11.11 P25321 GHMGAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n39 A 1.45 BS01 III B 1 T51 G52 K83 E127 F129 S130 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 Y204 L205 E230 P236 F239 A240 D241 P243 Y247 D328 Y330 T52 G53 K84 E128 F130 S131 R134 K169 P170 E171 F188 L199 C200 G201 T202 P203 E204 Y205 L206 E231 P237 F240 A241 D242 P244 Y248 D329 Y331 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n39 A 1.45 BS02 8LZ A 1 L49 G50 V57 A70 M120 E121 E127 E170 N171 L173 T183 F327 L50 G51 V58 A71 M121 E122 E128 E171 N172 L174 T184 F328 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3a A 1.40 BS02 MPD A 1 V15 F18 F100 L152 E155 I303 Y306 V18 F21 F103 L155 E158 I306 Y309 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3a A 1.40 BS03 46P A 1 L49 V57 E127 E170 N171 L173 T183 D184 F327 L52 V60 E130 E173 N174 L176 T186 D187 F330 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3b A 1.64 BS01 III B 1 Q84 H87 E127 F129 S130 R133 D166 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 Y204 E230 P236 F239 A240 D241 P243 D328 Y330 Q80 H83 E123 F125 S126 R129 D162 K164 P165 E166 F183 L194 C195 G196 T197 P198 E199 Y200 E226 P232 F235 A236 D237 P239 D324 Y326 2.7.11.11 P25321 AAAKKGSEQESVKEFLAKAKEEFLKKWESPQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3b A 1.64 BS02 BJN A 1 L49 V57 E127 E170 N171 L173 T183 F327 L45 V53 E123 E166 N167 L169 T179 F323 2.7.11.11 P25321 AAAKKGSEQESVKEFLAKAKEEFLKKWESPQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3c A 1.77 BS01 III B 1 G52 S53 Q84 H87 E127 F129 S130 R133 D166 K168 P169 E170 F187 T197 L198 C199 G200 T201 P202 E203 Y204 E230 P236 F239 A240 Y247 D328 Y330 G54 S55 Q86 H89 E129 F131 S132 R135 D168 K170 P171 E172 F189 T199 L200 C201 G202 T203 P204 E205 Y206 E232 P238 F241 A242 Y249 D330 Y332 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3c A 1.77 BS02 8M2 A 1 L49 V57 E127 E170 N171 T183 D184 F327 L51 V59 E129 E172 N173 T185 D186 F329 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3d A 1.77 BS02 8NE A 1 L49 G50 V57 A70 M120 E121 Y122 V123 E127 L173 F327 L49 G50 V57 A70 M120 E121 Y122 V123 E127 L173 F327 2.7.11.11 P25321 GHMGAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3f A 1.68 BS02 463 A 1 L49 A70 M120 E127 E170 N171 L173 T183 L40 A59 M108 E115 E158 N159 L161 T171 2.7.11.11 P25321 KKGSEQESVKEFLAKAKEEFLKKWESPTAQLDHFDRIKTLGTGSRVMLVKHKETGNHYAMKILDKQKVVKLQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 5n3f A 1.68 BS03 463 A 2 E17 K21 E11 K15 2.7.11.11 P25321 KKGSEQESVKEFLAKAKEEFLKKWESPTAQLDHFDRIKTLGTGSRVMLVKHKETGNHYAMKILDKQKVVKLQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 5n3g A 1.16 BS01 8KB A 1 F54 D166 D184 G186 F187 F44 D156 D174 G176 F177 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3g A 1.16 BS02 8KB A 2 E86 T197 E76 T187 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3h A 1.36 BS01 NCA A 1 A70 V104 M120 E121 Y122 V123 L173 T183 F327 A60 V94 M110 E111 Y112 V113 L163 T173 F317 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3i A 1.14 BS01 BJQ A 1 T278 K279 L284 T268 K269 L274 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3l A 1.38 BS02 MPD A 2 E86 L89 N90 R93 E349 E76 L79 N80 R83 E339 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3l A 1.38 BS03 E5E A 1 V57 A70 V104 M120 E121 Y122 V123 E127 E170 N171 L173 T183 D184 F327 V47 A60 V94 M110 E111 Y112 V113 E117 E160 N161 L163 T173 D174 F317 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3m A 1.23 BS01 DAR A 1 F129 R133 K168 P169 E170 E203 Y204 E230 P236 F119 R123 K158 P159 E160 E193 Y194 E220 P226 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3n A 1.22 BS03 152 A 1 T65 G66 N67 H68 P321 T55 G56 N57 H58 P311 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3o A 1.32 BS01 5AO A 1 E86 K189 R190 K192 E74 K177 R178 K180 2.7.11.11 P25321 ESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3o A 1.32 BS02 5AO A 2 L49 V57 A70 E121 Y122 V123 L173 T183 D184 F327 L37 V45 A58 E109 Y110 V111 L161 T171 D172 F315 2.7.11.11 P25321 ESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3o A 1.32 BS03 5AO A 3 W30 R93 D161 R190 V191 K192 W18 R81 D149 R178 V179 K180 2.7.11.11 P25321 ESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3q A 1.31 BS02 3AB A 2 L40 D41 F43 D44 R45 V60 I335 R336 L29 D30 F32 D33 R34 V49 I324 R325 2.7.11.11 P25321 QESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3r A 1.36 BS01 CDT A 1 L40 F43 D44 R45 V60 I335 V337 L29 F32 D33 R34 V49 I324 V326 2.7.11.11 P25321 QESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3t A 1.21 BS01 8K2 A 1 L40 F43 R45 V60 I335 L30 F33 R35 V50 I325 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n3t A 1.21 BS02 8K2 A 2 S139 P141 H142 R144 F145 T299 T300 I305 V310 E311 P313 S129 P131 H132 R134 F135 T289 T290 I295 V300 E301 P303 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n4i A 1.59 BS02 BCT A 1 Y280 P281 A282 Q284 E291 V292 Y274 P275 A276 Q278 E285 V286 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAAREGFPAVVGVI 5n4n A 2.09 BS02 8M8 A 1 L44 F49 A65 L120 E121 R122 V126 L174 I185 L12 F17 A33 L88 E89 R90 V94 L142 I153 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n4o A 2.22 BS02 8MB A 1 A65 K67 L120 E121 L174 D186 A31 K33 L86 E87 L140 D152 2.7.11.1 P11309 PLESQYQVGPLLGSGGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n4r A 2.13 BS02 8MQ A 1 A65 L174 I185 A33 L142 I153 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n4u A 2.20 BS01 III B 1 G48 D128 F130 D131 I133 T134 D167 D170 E171 D202 G203 T204 V206 D234 G238 D239 I240 E243 G15 D95 F97 D98 I100 T101 D134 D137 E138 D169 G170 T171 V173 D201 G205 D206 I207 E210 2.7.11.1 P11309 LESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n4u A 2.20 BS02 8MZ A 1 L44 A65 K67 I104 L120 R122 V126 L174 I185 D186 L11 A32 K34 I71 L87 R89 V93 L141 I152 D153 2.7.11.1 P11309 LESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n4v A 1.85 BS02 8MW A 1 L44 F49 V52 K67 L120 R122 V126 L174 I185 D186 L12 F17 V20 K35 L88 R90 V94 L142 I153 D154 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n4x A 2.20 BS02 8MT A 1 L44 F49 V52 A65 K67 I104 E121 R122 P123 L174 D186 L12 F17 V20 A33 K35 I71 E88 R89 P90 L141 D153 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n4y A 2.56 BS02 8N5 A 1 L44 A65 K67 I104 L120 E121 L174 D186 L12 A33 K35 I72 L88 E89 L142 D154 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n4z A 2.26 BS02 8MK A 1 F49 A65 K67 E121 R122 P123 L174 D186 F16 A32 K34 E88 R89 P90 L141 D153 2.7.11.1 P11309 LESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n50 A 1.92 BS02 8MN A 1 F49 V52 A65 K67 L120 E121 R122 L174 D186 F17 V20 A33 K35 L88 E89 R90 L142 D154 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n51 A 2.12 BS02 8N8 A 1 L44 A65 I104 E121 R122 L174 I185 L12 A29 I68 E85 R86 L138 I149 2.7.11.1 P11309 PLESQYQVGPLLGSSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n5p B 1.98 BS01 CA B 1 D653 N655 D657 D659 D664 D10 N12 D14 D16 D21 A0AEF3 HMASKPVWGDVNCDGDVNVADVVLLNKWLNNNADYAMTDQGKVNADCFNPQDANGGAVDASKVDLTKTDSDAIIKSVVHLITLPAKG 5n5p B 1.98 BS02 CA B 2 D689 F691 D707 D712 D46 F48 D64 D69 A0AEF3 HMASKPVWGDVNCDGDVNVADVVLLNKWLNNNADYAMTDQGKVNADCFNPQDANGGAVDASKVDLTKTDSDAIIKSVVHLITLPAKG 5n5p D 1.98 BS02 CA D 2 D689 F691 N692 D707 D712 D46 F48 N49 D64 D69 A0AEF3 HMASKPVWGDVNCDGDVNVADVVLLNKWLNNNADYAMTDQGKVNADCFNPQDANGGAVDASKVDLTKTDSDAIIKSVVHLITLPAKG 5n7y A BS01 ZN A 1 C11 I13 C14 C30 C33 C12 I14 C15 C31 C34 P37534 SMDETVKLNHTCVICDQEKNRGIHLYTKFICLDCERKVISTSTSDPDYA 5n9k A 1.64 BS01 8QK A 1 R43 L45 V53 V66 K68 I95 F113 E114 V116 M163 I174 D175 R42 L44 V52 V65 K67 I94 F112 E113 V115 M162 I173 D174 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKD 5n9l A 1.79 BS01 8QH A 1 R47 G48 S51 V53 V66 K68 F113 V116 M163 I174 D175 R46 G47 S50 V52 V65 K67 F112 V115 M162 I173 D174 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKD 5niq A BS01 D6M A 1 K14 R17 R18 S39 K13 R16 R17 S38 HQGTFTSDLSKQKDSRRAQDFIEWLKNGGPSSGAPPPS 5nku A 2.00 BS01 HEM A 1 I59 R60 Y61 A62 L70 I88 I90 K92 W96 F108 H114 T115 G118 L119 L122 V125 R127 L129 F141 T143 F145 L158 L159 M162 E167 W168 E174 I56 R57 Y58 A59 L67 I85 I87 K89 W93 F105 H111 T112 G115 L116 L119 V122 R124 L126 F138 T140 F142 L155 L156 M159 E164 W165 E171 B8HNS6 29142780 PNNRYSFIGGRTGQWQVVKIRNVLGPGLQLVEKVNILNGAVPLDSAWRLQGFASNIRYAIRTELEALQAVQPMLNRAEAILAVLIPIKKSAQWWEMAQDERRDIFERESHHTAVGLEYLPGVARRLLHCRDLGEEFDFLTWFEFAPEHSSAFNELLLRMRASKEWEYVEREVEVWLKRL 5nqz A 1.63 BS01 ZN A 1 H168 E202 H95 E129 Q9JXV4 AADIGAGLADALTAPLDHKDKGLQSLTLDQSVRKNEKLKLAAQGAEKTYGNGDSLNTGKLKNDKVSRFDFIRQIEVDGQLITLESGEFQVYKQSHSALTAFQTEQIQDSEHSGKMVAKRQFRIGDIAGEHTSFDKLPEGGRATYRGTAFGSDDAGGKLTYTIDFAAKQGNGKIEHLKSPELNVDLAAADIKPDGKRHAVISGSVLYNQAEKGSYSLGIFGGKAQEVAGSAEVKTVYYTKDTNNNLTLVGIRHIGLAAKQLEHHHHHH 5nqz A 1.63 BS02 ZN A 2 D266 H270 D193 H197 Q9JXV4 AADIGAGLADALTAPLDHKDKGLQSLTLDQSVRKNEKLKLAAQGAEKTYGNGDSLNTGKLKNDKVSRFDFIRQIEVDGQLITLESGEFQVYKQSHSALTAFQTEQIQDSEHSGKMVAKRQFRIGDIAGEHTSFDKLPEGGRATYRGTAFGSDDAGGKLTYTIDFAAKQGNGKIEHLKSPELNVDLAAADIKPDGKRHAVISGSVLYNQAEKGSYSLGIFGGKAQEVAGSAEVKTVYYTKDTNNNLTLVGIRHIGLAAKQLEHHHHHH 5nqz A 1.63 BS03 ZN A 3 H324 H326 H263 H265 Q9JXV4 AADIGAGLADALTAPLDHKDKGLQSLTLDQSVRKNEKLKLAAQGAEKTYGNGDSLNTGKLKNDKVSRFDFIRQIEVDGQLITLESGEFQVYKQSHSALTAFQTEQIQDSEHSGKMVAKRQFRIGDIAGEHTSFDKLPEGGRATYRGTAFGSDDAGGKLTYTIDFAAKQGNGKIEHLKSPELNVDLAAADIKPDGKRHAVISGSVLYNQAEKGSYSLGIFGGKAQEVAGSAEVKTVYYTKDTNNNLTLVGIRHIGLAAKQLEHHHHHH 5nue A 1.35 BS01 NAD A 1 G12 G15 Q16 I17 D43 I44 V88 G89 G90 F91 P92 I109 Q113 V130 A131 N132 L156 H188 S243 A247 G11 G14 Q15 I16 D42 I43 V87 G88 G89 F90 P91 I108 Q112 V129 A130 N131 L155 H187 S242 A246 1.1.1.37 P93819 29194485 AKEPVRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVANPANTNALILKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNHSSSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQRGAAIIKARKLSSALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGLIYSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKEEKDLAYSCLS 5nue A 1.35 BS02 PEO A 1 R163 G166 Q167 R231 R162 G165 Q166 R230 1.1.1.37 P93819 29194485 AKEPVRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVANPANTNALILKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNHSSSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQRGAAIIKARKLSSALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGLIYSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKEEKDLAYSCLS 5nue A 1.35 BS03 PEO A 2 K142 E143 P146 K141 E142 P145 1.1.1.37 P93819 29194485 AKEPVRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVANPANTNALILKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNHSSSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQRGAAIIKARKLSSALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGLIYSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKEEKDLAYSCLS 5nue B 1.35 BS01 PEO A 3 R27 A61 A62 R27 A61 A62 1.1.1.37 P93819 29194485 MAKEPVRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVANPANTNALILKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNHSSSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQRGAAIIKARKLSSALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGLIYSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKEEKDLAYSCLS 5nue B 1.35 BS03 PEO B 1 R163 Q167 R231 R163 Q167 R231 1.1.1.37 P93819 29194485 MAKEPVRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVANPANTNALILKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNHSSSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQRGAAIIKARKLSSALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGLIYSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKEEKDLAYSCLS 5nue B 1.35 BS05 PEO B 3 G232 S242 S243 G232 S242 S243 1.1.1.37 P93819 29194485 MAKEPVRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVANPANTNALILKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNHSSSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQRGAAIIKARKLSSALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGLIYSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKEEKDLAYSCLS 5nue C 1.35 BS02 PEO C 1 Q16 R239 L241 Q16 R239 L241 1.1.1.37 P93819 29194485 MAKEPVRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVANPANTNALILKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNHSSSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQRGAAIIKARKLSSALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGLIYSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKEEKDLAYSCLS 5nyn A 1.60 BS01 GSH A 1 P12 M38 K49 C67 A68 D69 K72 P9 M35 K46 C64 A65 D66 K69 I0BZV0 29453875 RPTSVEMEPIDDSHHLDKILLQARELSQPIIIDWMASWCRKCIYLKPKLEKLAAEYDTKIKFYCADVNKVPQALVKRGNISKMPTIQLWKDGEMKAEVIGGHKAWLVIEEVREMIQKFV 5o22 A 2.10 BS01 C3R A 1 Y50 K54 I170 I232 P260 G261 G264 P265 V268 Y44 K48 I164 I226 P254 G255 G258 P259 V262 1.5.1.5,3.5.4.9 P24186 29142318 AAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQ 5o22 C 2.10 BS01 C3R C 1 Y50 K54 I232 P260 G261 G264 P265 T267 Y49 K53 I231 P259 G260 G263 P264 T266 1.5.1.5,3.5.4.9 P24186 29142318 AAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDP 5o22 D 2.10 BS01 C3R D 1 Y50 K54 I232 P260 G261 G264 P265 T267 V268 Y43 K47 I225 P248 G249 G252 P253 T255 V256 1.5.1.5,3.5.4.9 P24186 29142318 GAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDP 5o5c A 2.10 BS01 PLP A 1 L108 G168 T169 H214 G269 T271 D296 A298 D325 H327 K328 L84 G144 T145 H190 G245 T247 D272 A274 D301 H303 K304 4.1.1.- D4I245 29428557 HDFIFNDHQLSAWARQTEQVLALMTETVKGVEKPFSGILPHELAREFSGVDLDQGSNEAALEELKKLYLRDAVWFHHPKYVAHLNCPVVLPSLLAEQIMAAVNSSVDTWDQSAGGTLIEQKVIDWTLSRIGLPAGADGIFTSGGTQSNLMAMLLARDSWCAAHHPGHLIKHRGLPHDAAKWRVFTSKLSHFSIQKSMAILGLGYDAVIPVDYDERYRMDVDCLKQEVQRCLQQGLIPVAVVATSGTTDFGSIDPLGAISELCKHHGMWMHVDAAYGCGLLVSESHRPRLAGIEKADSVTVDYHKSFFQTVSCGAFFVRDKHHLSHVTTPNLVNKSIQTTRRFDALKMWLTLRVSGPMALGNAFDDILALTQIAHQLLNAHPAIEVLHVPELTTQIFRYVPLTDEINTNIRKAVFRSGNAVIAGTKVNGRQYLKFTLLNPNTTAADIEDVIALIVHYGREQVRGP 5o5c A 2.10 BS02 PLP B 1 T377 T378 T338 T339 4.1.1.- D4I245 29428557 HDFIFNDHQLSAWARQTEQVLALMTETVKGVEKPFSGILPHELAREFSGVDLDQGSNEAALEELKKLYLRDAVWFHHPKYVAHLNCPVVLPSLLAEQIMAAVNSSVDTWDQSAGGTLIEQKVIDWTLSRIGLPAGADGIFTSGGTQSNLMAMLLARDSWCAAHHPGHLIKHRGLPHDAAKWRVFTSKLSHFSIQKSMAILGLGYDAVIPVDYDERYRMDVDCLKQEVQRCLQQGLIPVAVVATSGTTDFGSIDPLGAISELCKHHGMWMHVDAAYGCGLLVSESHRPRLAGIEKADSVTVDYHKSFFQTVSCGAFFVRDKHHLSHVTTPNLVNKSIQTTRRFDALKMWLTLRVSGPMALGNAFDDILALTQIAHQLLNAHPAIEVLHVPELTTQIFRYVPLTDEINTNIRKAVFRSGNAVIAGTKVNGRQYLKFTLLNPNTTAADIEDVIALIVHYGREQVRGP 5o5c B 2.10 BS02 PLP B 1 L108 G167 G168 T169 N172 H214 G269 T271 D296 A298 D325 H327 K328 L85 G144 G145 T146 N149 H191 G246 T248 D273 A275 D302 H304 K305 4.1.1.- D4I245 29428557 PHDFIFNDHQLSAWARQTEQVLALMTETVKGVEKPFSGILPHELAREFSGVDLDQGSNEAALEELKKLYLRDAVWFHHPKYVAHLNCPVVLPSLLAEQIMAAVNSSVDTWDQSAGGTLIEQKVIDWTLSRIGLPAGADGIFTSGGTQSNLMAMLLARDSWCAAHHPGHLIKHRGLPHDAAKWRVFTSKLSHFSIQKSMAILGLGYDAVIPVDYDERYRMDVDCLKQEVQRCLQQGLIPVAVVATSGTTDFGSIDPLGAISELCKHHGMWMHVDAAYGCGLLVSESHRPRLAGIEKADSVTVDYHKSFFQTVSCGAFFVRDKHHLSHVTGTPNLVNKSIQTTRRFDALKMWLTLRVSGPMALGNAFDDILALTQIAHQLLNAHPAIEVLHVPELTTQIFRYVPDALTDEINTNIRKAVFRSGNAVIAGTKVNGRQYLKFTLLNPNTTAADIEDVIALIVHYGREQVRGP 5o5e A 3.40 BS01 P6L A 1 A203 V207 W243 R377 A182 V186 W222 R356 2.7.8.15 Q9H3H5 PMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGVISGAVFLIILFCFIPFPFLPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDTFCYFAGMTFAGVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCPRHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNNMTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLV 5o5e A 3.40 BS02 9LH A 1 Q44 L46 E56 W122 K125 L126 L175 N182 N185 I186 A188 G189 I190 N191 F249 D252 F286 L293 R301 H302 R303 I304 Q37 L39 E49 W104 K107 L108 L154 N161 N164 I165 A167 G168 I169 N170 F228 D231 F265 L272 R280 H281 R282 I283 2.7.8.15 Q9H3H5 PMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGVISGAVFLIILFCFIPFPFLPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDTFCYFAGMTFAGVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCPRHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNNMTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLV 5o8r A 2.80 BS01 FAD A 1 G14 P15 F16 D36 Q37 N38 W43 H44 L54 Q55 T56 V120 G155 T156 G157 P158 F346 N380 P391 D392 L393 G12 P13 F14 D34 Q35 N36 W41 H42 L52 Q53 T54 V118 G153 T154 G155 P156 F344 N378 P389 D390 L391 1.14.13.59 D4I246 29428557 NTIYDFIGIGIGPFNLGLACLSEPVEGLNGVFLDQNPGFDWHTGMMLESAHLQTPFMADLVTLADPTSPYSLLNFMKQKGKLYSFYIREDFFLMRKEYNQYCQWAAERLGNLRWNTRVEYVSYDDNLQCYRVRSTDTVSGKQQEWLAHRLVLGTGPSAWSPACSQPYRERFVHSSEYLLNKEKLQKKRSITVLGSGQSAAEIYYDLLTDIDRFGYQLNWITRAPRFYPLEYTKLTLEMTSPEWIDYFHSLPAAKRDELNASQKNLYKGINSSLINAIYDLLYVKQLDGKLDVNLFTHSELTDMRWLAEGEFELKLHQQEQDRAYSRRTEGLVMATGYHYQPPAFVEGIQQRIQWDEKDRYDVQRNYSIDRHNQVFVQNAELHTHGFVTPDLGMACYRNSVLLREITGREVYPVERQIAFQTFPAQSE 5o8r A 2.80 BS02 NAP A 1 Q55 R97 P163 L195 G196 S197 G198 S200 T223 R224 A225 Y229 K265 K269 S300 L302 A336 T337 G338 P391 Q53 R95 P161 L193 G194 S195 G196 S198 T221 R222 A223 Y227 K263 K267 S298 L300 A334 T335 G336 P389 1.14.13.59 D4I246 29428557 NTIYDFIGIGIGPFNLGLACLSEPVEGLNGVFLDQNPGFDWHTGMMLESAHLQTPFMADLVTLADPTSPYSLLNFMKQKGKLYSFYIREDFFLMRKEYNQYCQWAAERLGNLRWNTRVEYVSYDDNLQCYRVRSTDTVSGKQQEWLAHRLVLGTGPSAWSPACSQPYRERFVHSSEYLLNKEKLQKKRSITVLGSGQSAAEIYYDLLTDIDRFGYQLNWITRAPRFYPLEYTKLTLEMTSPEWIDYFHSLPAAKRDELNASQKNLYKGINSSLINAIYDLLYVKQLDGKLDVNLFTHSELTDMRWLAEGEFELKLHQQEQDRAYSRRTEGLVMATGYHYQPPAFVEGIQQRIQWDEKDRYDVQRNYSIDRHNQVFVQNAELHTHGFVTPDLGMACYRNSVLLREITGREVYPVERQIAFQTFPAQSE 5o8r B 2.80 BS01 FAD B 1 G12 I13 G14 P15 F16 D36 Q37 N38 W43 H44 M47 L54 Q55 R97 T118 V120 G155 T156 G157 Y339 F346 N380 P391 D392 L393 G9 I10 G11 P12 F13 D33 Q34 N35 W40 H41 M44 L51 Q52 R94 T115 V117 G152 T153 G154 Y336 F343 N377 P388 D389 L390 1.14.13.59 D4I246 29428557 TIYDFIGIGIGPFNLGLACLSEPVEGLNGVFLDQNPGFDWHTGMMLESAHLQTPFMADLVTLADPTSPYSLLNFMKQKGKLYSFYIREDFFLMRKEYNQYCQWAAERLGNLRWNTRVEYVSYDDNLQCYRVRSTDTVSGKQQEWLAHRLVLGTGPSAWSPACSQPYRERFVHSSEYLLNKEKLQKKRSITVLGSGQSAAEIYYDLLTDIDRFGYQLNWITRAPRFYPLEYTKLTLEMTSPEWIDYFHSLPAAKRDELNASQKNLYKGINSSLINAIYDLLYVKQLDGKLDVNLFTHSELTDMRWLAEGEFELKLHQQEQDRAYSRRTEGLVMATGYHYQPPAFVEGIQQRIQWDEKDRYDVQRNYSIDRHNQVFVQNAELHTHGFVTPDLGMACYRNSVLLREITGREVYPVERQIAFQTFPAQSEM 5o8r B 2.80 BS02 NAP B 1 H53 R97 L195 G196 S197 G198 Q199 S200 E203 T223 R224 Y229 K269 L302 A336 T337 G338 Y339 H50 R94 L192 G193 S194 G195 Q196 S197 E200 T220 R221 Y226 K266 L299 A333 T334 G335 Y336 1.14.13.59 D4I246 29428557 TIYDFIGIGIGPFNLGLACLSEPVEGLNGVFLDQNPGFDWHTGMMLESAHLQTPFMADLVTLADPTSPYSLLNFMKQKGKLYSFYIREDFFLMRKEYNQYCQWAAERLGNLRWNTRVEYVSYDDNLQCYRVRSTDTVSGKQQEWLAHRLVLGTGPSAWSPACSQPYRERFVHSSEYLLNKEKLQKKRSITVLGSGQSAAEIYYDLLTDIDRFGYQLNWITRAPRFYPLEYTKLTLEMTSPEWIDYFHSLPAAKRDELNASQKNLYKGINSSLINAIYDLLYVKQLDGKLDVNLFTHSELTDMRWLAEGEFELKLHQQEQDRAYSRRTEGLVMATGYHYQPPAFVEGIQQRIQWDEKDRYDVQRNYSIDRHNQVFVQNAELHTHGFVTPDLGMACYRNSVLLREITGREVYPVERQIAFQTFPAQSEM 5oc2 A 2.85 BS01 FAD A 1 I15 G16 G18 T19 W20 D40 P41 S46 I48 A49 A50 G51 K56 I57 V192 A222 G223 W241 C342 D344 G369 G371 N372 G373 A374 M375 I14 G15 G17 T18 W19 D39 P40 S45 I47 A48 A49 G50 K55 I56 V191 A221 G222 W240 C341 D343 G368 G370 N371 G372 A373 M374 O42629 29445091 APSILSTESSIIVIGAGTWGCSTALHLARRGYKDVTVLDPHPVPSPIAAGNDINKIMEHSELKDGSSDPRSAAFSTFTRAALKAWKTDPVFQPYFHETGFIISGHTPALIDHIRKDEVEPSETNFVKLETAEDFRRTMPPGVLTGDFPGWKGWLHKSGAGWIHAKKAMISAFNEAKRLGVRFVTGSPEGNVVSLVYEDGDVVGARTADGRVHKAHRTILSAGAGSDSLLDFKKQLRPTAWTLCHIQMGPEEVKQYRNLPVLFNIAKGFFMEPDEDKHELKICDEHPGYCNFLPCPNRPGQECSVPFAKHQIPLEAEARARDFLHDTMPHLADRPLSFARICWDADTPDRAFLIDRHPEHPSLLVAVGGSGNGAMQMPTIGGFIADALESKLQKEVKDIVRWRPETAVDRDWRATQNRFGGPDRIMDFQQVGEDQWTKIGES 5oc2 B 2.85 BS01 FAD B 1 I15 G16 G18 T19 W20 L39 D40 P41 S46 I48 A49 A50 G51 K56 I57 G190 V192 A222 G223 L229 W241 C342 D344 G371 N372 G373 A374 M375 I14 G15 G17 T18 W19 L38 D39 P40 S45 I47 A48 A49 G50 K55 I56 G189 V191 A221 G222 L228 W240 C341 D343 G370 N371 G372 A373 M374 O42629 29445091 APSILSTESSIIVIGAGTWGCSTALHLARRGYKDVTVLDPHPVPSPIAAGNDINKIMEHSELKDGSSDPRSAAFSTFTRAALKAWKTDPVFQPYFHETGFIISGHTPALIDHIRKDEVEPSETNFVKLETAEDFRRTMPPGVLTGDFPGWKGWLHKSGAGWIHAKKAMISAFNEAKRLGVRFVTGSPEGNVVSLVYEDGDVVGARTADGRVHKAHRTILSAGAGSDSLLDFKKQLRPTAWTLCHIQMGPEEVKQYRNLPVLFNIAKGFFMEPDEDKHELKICDEHPGYCNFLPCPNRPGQECSVPFAKHQIPLEAEARARDFLHDTMPHLADRPLSFARICWDADTPDRAFLIDRHPEHPSLLVAVGGSGNGAMQMPTIGGFIADALESKLQKEVKDIVRWRPETAVDRDWRATQNRFGGPDRIMDFQQVGEDQWTKIGES 5okd C 3.10 BS01 HEM C 1 L41 Q44 I45 G48 L49 L51 R80 H83 A84 A87 F90 T126 G130 Y131 L133 P134 F179 H182 F183 P186 L40 Q43 I44 G47 L48 L50 R79 H82 A83 A86 F89 T125 G129 Y130 L132 P133 F178 H181 F182 P185 P00157 TNIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLLKW 5okd C 3.10 BS02 HEM C 2 W31 G34 L37 G38 F90 H97 V98 R100 S106 F109 W113 G116 L119 L120 H196 L197 L200 S205 N206 W30 G33 L36 G37 F89 H96 V97 R99 S105 F108 W112 G115 L118 L119 H195 L196 L199 S204 N205 P00157 TNIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLLKW 5okd C 3.10 BS03 9XE C 1 F18 L21 S35 G38 I39 L197 H201 S205 F220 I229 A232 F17 L20 S34 G37 I38 L196 H200 S204 F219 I228 A231 P00157 TNIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLLKW 5okd D 3.10 BS01 HEC D 1 V32 V36 C37 C40 H41 N105 P111 I116 R120 Y126 L130 L131 F153 I158 G159 M160 P163 V31 V35 C36 C39 H40 N104 P110 I115 R119 Y125 L129 L130 F152 I157 G158 M159 P162 P00125 DLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEDEAKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYNEVLEFDDGTPATMSQVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLLPLVYAMKRHKWSVLKSRKLAYRPP 5ol0 A 1.99 BS01 III C 1 E68 D69 F74 H144 V188 F189 F190 G191 E192 N193 L194 D196 F199 Q220 V221 H222 P223 E62 D63 F68 H138 V182 F183 F184 G185 E186 N187 L188 D190 F193 Q214 V215 H216 P217 2.4.2.31,2.4.2.31 Q8I6E4 APHQEHVLGEPTLEGLAHYIREKNVRRILVLVGAGASVAAGIPDFRSPDTGIYANLGKYNLEDPTDAFSLTLLREKPEIFYSIARELNLWPGHFQPTAVHHFIRLLQDEGRLLRCCTQNIDGLEKAAGVSPELLVEAHGSFAAAACIECHTPFSIEQNYLEAMSGTVSRCSTCGGIVKPNVVFFGENLPDAFFDALHHDAPIAELVIIIGTSMQVHPFALLPCVVPKSVPRVVMNRERVGGLLFRFDVCRDVLFRGDCQENVVTLAEYLGLSEALAKRMRLSD 5ol0 A 1.99 BS02 ZN A 1 C152 C155 C176 C179 C146 C149 C170 C173 2.4.2.31,2.4.2.31 Q8I6E4 APHQEHVLGEPTLEGLAHYIREKNVRRILVLVGAGASVAAGIPDFRSPDTGIYANLGKYNLEDPTDAFSLTLLREKPEIFYSIARELNLWPGHFQPTAVHHFIRLLQDEGRLLRCCTQNIDGLEKAAGVSPELLVEAHGSFAAAACIECHTPFSIEQNYLEAMSGTVSRCSTCGGIVKPNVVFFGENLPDAFFDALHHDAPIAELVIIIGTSMQVHPFALLPCVVPKSVPRVVMNRERVGGLLFRFDVCRDVLFRGDCQENVVTLAEYLGLSEALAKRMRLSD 5ol0 B 1.99 BS01 III D 1 T71 F74 H144 V187 V188 F189 F190 G191 E192 N193 L194 D196 F199 Q220 V221 H222 P223 T46 F49 H119 V162 V163 F164 F165 G166 E167 N168 L169 D171 F174 Q195 V196 H197 P198 2.4.2.31,2.4.2.31 Q8I6E4 APHQEHVLGEPTLEGLAHYIREKNVRRILVLVGAGASVAAGIPDFTDAFSLTLLREKPEIFYSIARELNLWPGHFQPTAVHHFIRLLQDEGRLLRCCTQNIDGLEKAAGVSPELLVEAHGSFAAAACIECHTPFSIEQNYLEAMSGTVSRCSTCGGIVKPNVVFFGENLPDAFFDALHHDAPIAELVIIIGTSMQVHPFALLPCVVPKSVPRVVMNRERVGGLLFRFVCRDVLFRGDCQENVVTLAEYLGLSEALAKRMRLSD 5ol0 B 1.99 BS02 ZN B 1 C152 C155 C176 C179 C127 C130 C151 C154 2.4.2.31,2.4.2.31 Q8I6E4 APHQEHVLGEPTLEGLAHYIREKNVRRILVLVGAGASVAAGIPDFTDAFSLTLLREKPEIFYSIARELNLWPGHFQPTAVHHFIRLLQDEGRLLRCCTQNIDGLEKAAGVSPELLVEAHGSFAAAACIECHTPFSIEQNYLEAMSGTVSRCSTCGGIVKPNVVFFGENLPDAFFDALHHDAPIAELVIIIGTSMQVHPFALLPCVVPKSVPRVVMNRERVGGLLFRFVCRDVLFRGDCQENVVTLAEYLGLSEALAKRMRLSD 5opj A 2.05 BS01 AHR A 1 W81 Y166 E217 H264 N266 E320 E339 Y395 C416 Q688 Q689 W57 Y142 E193 H240 N242 E296 E315 Y371 C392 Q656 Q657 A0A1H7THV3 HQVSYFSLQDVKLLSSPFLQAQQTDLHYILALDPDRLSAPFLREAGLTPKAPSYTNWENTGLDGHIGGHYLSALSMMYAATGDTAIYHRLNYMLNELHRAQQAVGTGFIGGTPGSLQLWKEIKAGDIRAGGFSLNGKWVPLYNIHKTYAGLRDAYLYAHSDLARQMLIDLTDWMIDITSGLSDNQMQDMLRSEHGGLNETFADVAEITGDKKYLKLARRFSHKVILDPLIKNEDRLNGMHANTQIPKVIGYKRVAEVSKNDKDWNHAAEWDHAARFFWNTVVNHRSVCIGGNSVREHFHPSDNFTSMLNDVQGPETCNTYNMLRLTKMLYQNSGDVDNSNKPDPRYVDYYERALYNHILSSQEPDKGGFVYFTPMRPGHYRVYSQPETSMWCCVGSGLENHTKYGEFIYAHQQDTLYVNLFIPSQLNWKEQGVTLTQETLFPDDEKVTLRIDKAAKKNLTLMIRIPEWAYEITINGKKHLSDIQTGASTYLPIRRKWKKGDMITFHLPMKVSLEQIPDKKDYYAFLYGPIVLATSTGTENLDGIYADDSRGGHIAHGRQTPLQEIPMLIGNPDSIRHSLHKLSGSKLAFSYDGNVYPTQSLELIPFFRLHNSRYAVYFRQASEEQFKTIQEEMATAERKATELANRTVDLIFPGEQQPESDHSIQYEASETGTHKDRHFRRAKGWFSYNLKIKEEASQLMITVRQEDRNKAVILLNNEKLTVHPTVSKADKDGFIRLCYLLPRKLKVGSCEILFKPDGTEWTSAVYEVRLLK 5opj A 2.05 BS02 ZN A 1 E339 C341 C416 C417 E315 C317 C392 C393 A0A1H7THV3 HQVSYFSLQDVKLLSSPFLQAQQTDLHYILALDPDRLSAPFLREAGLTPKAPSYTNWENTGLDGHIGGHYLSALSMMYAATGDTAIYHRLNYMLNELHRAQQAVGTGFIGGTPGSLQLWKEIKAGDIRAGGFSLNGKWVPLYNIHKTYAGLRDAYLYAHSDLARQMLIDLTDWMIDITSGLSDNQMQDMLRSEHGGLNETFADVAEITGDKKYLKLARRFSHKVILDPLIKNEDRLNGMHANTQIPKVIGYKRVAEVSKNDKDWNHAAEWDHAARFFWNTVVNHRSVCIGGNSVREHFHPSDNFTSMLNDVQGPETCNTYNMLRLTKMLYQNSGDVDNSNKPDPRYVDYYERALYNHILSSQEPDKGGFVYFTPMRPGHYRVYSQPETSMWCCVGSGLENHTKYGEFIYAHQQDTLYVNLFIPSQLNWKEQGVTLTQETLFPDDEKVTLRIDKAAKKNLTLMIRIPEWAYEITINGKKHLSDIQTGASTYLPIRRKWKKGDMITFHLPMKVSLEQIPDKKDYYAFLYGPIVLATSTGTENLDGIYADDSRGGHIAHGRQTPLQEIPMLIGNPDSIRHSLHKLSGSKLAFSYDGNVYPTQSLELIPFFRLHNSRYAVYFRQASEEQFKTIQEEMATAERKATELANRTVDLIFPGEQQPESDHSIQYEASETGTHKDRHFRRAKGWFSYNLKIKEEASQLMITVRQEDRNKAVILLNNEKLTVHPTVSKADKDGFIRLCYLLPRKLKVGSCEILFKPDGTEWTSAVYEVRLLK 5oqu B 2.32 BS01 ADP B 1 G48 K49 S51 V53 V66 K68 I95 E114 V116 N161 M163 I174 D175 G45 K46 S48 V50 V63 K65 I92 E111 V113 N158 M160 I171 D172 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5oqu A 2.32 BS01 ADP A 1 G46 G48 S51 V53 V66 K68 I95 E114 V116 H160 N161 M163 I174 D175 G43 G45 S48 V50 V63 K65 I92 E111 V113 H157 N158 M160 I171 D172 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5oqu A 2.32 BS02 A4B A 1 N118 F121 L124 P159 V162 I164 M221 S224 M225 N115 F118 L121 P156 V159 I161 M218 S221 M222 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5oqu A 2.32 BS04 MG A 2 K68 F113 I174 D175 K65 F110 I171 D172 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5oqu A 2.32 BS05 I6P A 1 K229 H234 H236 K226 H231 H233 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5orh A 1.75 BS01 A4N A 1 Q36 Y39 L41 V101 K102 D103 T108 A110 Q33 Y36 L38 V98 K99 D100 T105 A107 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5orh A 1.75 BS02 A4N A 2 F121 L124 I133 M137 I140 P159 V162 I164 M221 M225 F118 L121 I130 M134 I137 P156 V159 I161 M218 M222 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5orj B 1.99 BS03 ADP B 1 G48 K49 Y50 S51 V53 V66 K68 I95 E114 V116 H160 N161 M163 I174 D175 G45 K46 Y47 S48 V50 V63 K65 I92 E111 V113 H157 N158 M160 I171 D172 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5orj B 1.99 BS04 A4Q B 1 F121 L124 M137 I140 P159 V162 I164 M221 M225 F118 L121 M134 I137 P156 V159 I161 M218 M222 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5orj A 1.99 BS02 MG A 2 Y50 K77 D175 G177 Y48 K75 D173 G175 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5orj A 1.99 BS05 A4Q A 1 F121 Y136 M137 I140 P159 V162 I164 M221 M225 F119 Y134 M135 I138 P157 V160 I162 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5ork A 2.14 BS04 A4T A 1 N118 F121 L124 L128 I133 Y136 I140 P159 V162 I164 M221 M225 N115 F118 L121 L125 I130 Y133 I137 P156 V159 I161 M218 M222 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5os7 B 1.66 BS02 ATP B 1 V53 V66 E114 V116 M163 I174 V51 V64 E112 V114 M161 I172 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5os7 A 1.66 BS02 A8Q A 2 Q36 D37 Y39 L41 I69 K102 D103 T108 A110 Q34 D35 Y37 L39 I67 K100 D101 T106 A108 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5os7 A 1.66 BS03 ATP A 1 L45 G46 V53 V66 I95 E114 V116 M163 I174 L43 G44 V51 V64 I93 E112 V114 M161 I172 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5os8 A 1.55 BS01 J27 A 1 F121 L124 L128 Y136 I140 P159 V162 I164 M221 L222 M225 F119 L122 L126 Y134 I138 P157 V160 I162 M219 L220 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5os8 A 1.55 BS02 J27 A 2 E52 I69 K71 P72 D103 S106 E50 I67 K69 P70 D101 S104 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5os8 A 1.55 BS03 J27 A 3 E282 V285 Q290 V293 S294 P295 L298 E280 V283 Q288 V291 S292 P293 L296 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5os8 A 1.55 BS04 ATP A 1 V53 V66 I95 E114 V116 N118 M163 I174 V51 V64 I93 E112 V114 N116 M161 I172 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5osl A 1.95 BS01 ADP A 1 S51 V53 V66 K68 I95 E114 V116 H160 N161 M163 I174 D175 S50 V52 V65 K67 I94 E113 V115 H159 N160 M162 I173 D174 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5osl A 1.95 BS03 A9K A 1 N118 T119 F121 L124 L128 M137 P159 V162 I164 M221 M225 N117 T118 F120 L123 L127 M136 P158 V161 I163 M220 M224 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5osl A 1.95 BS04 A9K A 2 E52 I69 K71 P72 S106 E51 I68 K70 P71 S105 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5osz A 2.00 BS01 AHK A 1 L45 G46 V53 F121 L124 Y136 I140 P159 H160 V162 M163 I164 M221 M225 L43 G44 V51 F119 L122 Y134 I138 P157 H158 V160 M161 I162 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5osz A 2.00 BS02 AHK A 2 Q36 Y39 V67 I69 V101 K102 D103 T108 A110 Q34 Y37 V65 I67 V99 K100 D101 T106 A108 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5osz A 2.00 BS03 AHK A 3 L203 D205 Y239 L242 E264 L265 D266 P267 I272 L273 L201 D203 Y237 L240 E262 L263 D264 P265 I270 L271 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5ot5 A 1.63 BS01 AWK A 1 L45 L128 Y136 I140 P159 H160 V162 M163 I164 I174 M221 M225 L43 L126 Y134 I138 P157 H158 V160 M161 I162 I172 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5ot5 B 1.63 BS01 AWK B 1 G46 N118 F121 L124 L128 P159 H160 V162 M163 I174 M221 S224 M225 G44 N116 F119 L122 L126 P157 H158 V160 M161 I172 M219 S222 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5ot6 A 1.94 BS01 AJK A 1 N118 F121 L124 Y136 P159 H160 V162 I164 M221 M225 N117 F120 L123 Y135 P158 H159 V161 I163 M220 M224 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5otd B 1.57 BS01 AOW B 1 N118 F121 L128 Y136 I140 P159 H160 V162 M163 I164 I174 M221 M225 N115 F118 L125 Y133 I137 P156 H157 V159 M160 I161 I171 M218 M222 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5otd A 1.57 BS01 AOW A 1 N118 F121 P159 H160 V162 M163 I164 I174 M221 M225 N117 F120 P158 H159 V161 M162 I163 I173 M220 M224 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5oth A 1.69 BS01 AQ8 A 1 L45 G46 V53 N118 F121 Y125 P159 H160 V162 M163 M221 S224 M225 L43 G44 V51 N116 F119 Y123 P157 H158 V160 M161 M219 S222 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5oth B 1.69 BS01 AQ8 B 1 G46 V53 N118 L124 L128 Y136 M137 I140 P159 H160 V162 M163 I164 I174 M221 M225 G43 V50 N115 L121 L125 Y133 M134 I137 P156 H157 V159 M160 I161 I171 M218 M222 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5oti A 1.59 BS01 AOK A 1 V53 N118 F121 L124 Y125 M137 P159 H160 V162 M163 M221 M225 V51 N116 F119 L122 Y123 M135 P157 H158 V160 M161 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5otl A 1.57 BS01 AQT A 1 G46 N118 F121 L128 Y136 I140 P159 H160 V162 I164 M221 M225 G43 N115 F118 L121 Y129 I133 P152 H153 V155 I157 M214 M218 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5oto B 1.51 BS01 AQW B 1 V53 N118 F121 L128 I140 P159 H160 V162 I164 M221 M225 V50 N115 F118 L125 I137 P156 H157 V159 I161 M218 M222 2.7.11.1 P68400 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5oto A 1.51 BS01 AQW A 1 L45 V53 N118 Y136 I140 P159 H160 V162 I164 M221 M225 L44 V52 N117 Y135 I139 P158 H159 V161 I163 M220 M224 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5otq A 1.38 BS01 AUH A 1 L45 G46 V53 F121 Y125 T127 L128 Y136 I140 P159 H160 V162 I164 M221 M225 L43 G44 V51 F119 Y123 T125 L126 Y134 I138 P157 H158 V160 I162 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5otq A 1.38 BS02 AUH A 2 Q36 Y39 L41 V67 I69 D103 T108 A110 Q34 Y37 L39 V65 I67 D101 T106 A108 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5otr A 1.52 BS01 AU8 A 1 L124 Y125 L128 M137 I140 P159 V162 I164 M221 M225 L122 Y123 L126 M135 I138 P157 V160 I162 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5otr A 1.52 BS02 AU8 A 2 E282 V285 Q290 V293 P295 E280 V283 Q288 V291 P293 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5otr A 1.52 BS03 ATP A 1 V53 V66 I95 E114 V116 H160 M163 I174 V51 V64 I93 E112 V114 H158 M161 I172 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5oty A 1.48 BS02 AUW A 1 N118 L124 Y125 I140 P159 H160 V162 M163 I164 M221 M225 N116 L122 Y123 I138 P157 H158 V160 M161 I162 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5otz A 1.46 BS02 AUT A 1 F121 L124 Y125 I140 P159 V162 I164 M221 M225 F119 L122 Y123 I138 P157 V160 I162 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5oue B 2.01 BS01 AVZ B 1 N118 F121 L124 L128 Y136 P159 H160 V162 M163 I164 M221 M225 N117 F120 L123 L127 Y135 P158 H159 V161 M162 I163 M220 M224 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5oul A 1.34 BS01 AWE A 1 F121 Y125 L128 I133 Y136 M137 P159 V162 I164 M221 M225 F119 Y123 L126 I131 Y134 M135 P157 V160 I162 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5oul A 1.34 BS02 AWE A 2 Q290 V293 S294 P295 L298 Q288 V291 S292 P293 L296 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5oul A 1.34 BS03 AWE A 3 E282 R283 V285 Q290 E280 R281 V283 Q288 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5oul A 1.34 BS05 AWE A 5 L45 V66 V116 N118 M163 L43 V64 V114 N116 M161 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5oul A 1.34 BS06 AWE A 6 H160 N161 M163 I174 H158 N159 M161 I172 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5oum A 2.05 BS01 AVK A 1 N118 F121 Y136 P159 H160 V162 I164 M221 M225 N116 F119 Y134 P157 H158 V160 I162 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5ouu A 1.81 BS01 AWN A 1 L45 G46 L128 Y136 P159 H160 V162 M163 I164 M221 M225 L44 G45 L124 Y132 P155 H156 V158 M159 I160 M217 M221 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5ovk A 1.45 BS01 NDP A 1 G30 N32 R33 R55 C68 D69 V70 A97 G98 I99 T119 G17 N19 R20 R42 C55 D56 V57 A84 G85 I86 T106 1.1.1.100 P71534 ATAGRPAFVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQCDVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTEMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGGMGMGH 5ovk B 1.45 BS01 NDP B 1 G30 N32 R33 G34 I35 R55 C68 D69 V70 N96 A97 G98 I99 T119 I146 G147 Y161 K165 P191 G192 I194 T196 G17 N19 R20 G21 I22 R42 C55 D56 V57 N83 A84 G85 I86 T106 I133 G134 Y148 K152 P178 G179 I181 T183 1.1.1.100 P71534 ATAGRPAFVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQCDVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGGMGMGH 5owy A 1.90 BS02 B0W A 1 G135 L136 N282 N284 H341 H377 N484 Y573 E672 A673 S674 G675 G124 L125 N265 N267 H315 H351 N458 Y547 E646 A647 S648 G649 2.4.1.1 P00489 29454281 QISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 5owz A 1.85 BS03 B0Z A 1 E88 G135 L136 N282 N284 F285 R292 H341 H377 N484 Y573 E672 A673 S674 G675 E77 G124 L125 N265 N267 F268 R275 H315 H351 N458 Y547 E646 A647 S648 G649 2.4.1.1 P00489 29454281 QISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 5ox1 A 1.85 BS01 B1K A 1 E88 L136 N282 N284 R292 H341 H377 N484 Y573 E672 A673 S674 G675 E77 L125 N265 N267 R275 H315 H351 N458 Y547 E646 A647 S648 G649 2.4.1.1 P00489 29454281 QISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 5ox4 A 1.80 BS01 B1W A 1 G135 L136 N282 N284 F285 H341 H377 T378 N484 Y573 E672 A673 S674 G675 G124 L125 N265 N267 F268 H315 H351 T352 N458 Y547 E646 A647 S648 G649 2.4.1.1 P00489 29454281 QISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 5oyf A 1.54 BS01 B4Q A 1 L45 G46 V53 F121 L124 Y125 M137 P159 H160 V162 M163 M221 M225 L43 G44 V51 F119 L122 Y123 M135 P157 H158 V160 M161 M219 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5oyf A 1.54 BS02 B4Q A 2 Q36 Y39 I69 D103 T108 A110 Q34 Y37 I67 D101 T106 A108 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5u8q A 3.27 BS01 III B 1 D8 R10 N11 L33 R59 E91 E693 H697 S699 I700 F701 V702 P703 R704 D8 R10 N11 L33 R54 E86 E633 H637 S639 I640 F641 V642 P643 R644 2.7.10.1 P08069 EICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPCEKTTINNEYNYRCWTTNRCQKMCPSTCACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYARKVFENFLHNSIFVPRPYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGY 5u8q A 3.27 BS02 III B 2 N694 F695 H697 N698 F701 P703 R704 N634 F635 H637 N638 F641 P643 R644 2.7.10.1 P08069 EICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPCEKTTINNEYNYRCWTTNRCQKMCPSTCACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYARKVFENFLHNSIFVPRPYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGY 5ut7 A 1.85 BS03 NO2 A 2 R31 A110 R32 A111 P02185 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ut7 A 1.85 BS04 NO2 A 3 H82 E83 L86 D141 H83 E84 L87 D142 P02185 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ut7 A 1.85 BS05 NO2 A 4 S92 K96 S93 K97 P02185 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ut7 A 1.85 BS06 NO2 A 5 V66 T67 T70 V67 T68 T71 P02185 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ut7 A 1.85 BS07 NO2 A 6 G124 A125 G125 A126 P02185 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ut8 A 1.78 BS01 HEM A 1 T39 K42 F43 T67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 T39 K42 F43 T67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKAGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ut9 A 1.85 BS02 NO2 A 1 F43 V68 F43 V68 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKAGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ut9 A 1.85 BS03 NO2 A 2 R31 E109 A110 R31 E109 A110 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKAGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ut9 A 1.85 BS04 NO2 A 3 R31 K34 R31 K34 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKAGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5uta A 1.81 BS01 HEM A 1 T39 K42 F43 R45 Q64 T67 A71 L89 S92 H93 H97 I99 Y103 L104 T39 K42 F43 R45 Q64 T67 A71 L89 S92 H93 H97 I99 Y103 L104 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKQGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5uta A 1.81 BS02 NO2 A 1 L29 F43 Q64 V68 L29 F43 Q64 V68 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKQGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5uta A 1.81 BS03 NO2 A 2 R31 S35 E109 A110 R31 S35 E109 A110 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKQGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5uta A 1.81 BS05 NO2 A 4 W7 L76 H82 A134 L137 F138 W7 L76 H82 A134 L137 F138 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKQGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5uta A 1.81 BS07 NO2 A 6 L104 I107 S108 L135 F138 L104 I107 S108 L135 F138 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKQGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5uta A 1.81 BS09 NO2 A 8 L89 H93 L104 I142 L89 H93 L104 I142 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKQGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5utb A 1.78 BS01 HEM A 1 T39 K42 F43 R45 H64 T67 A68 A71 L89 S92 H93 H97 I99 Y103 L104 Y107 F138 T40 K43 F44 R46 H65 T68 A69 A72 L90 S93 H94 H98 I100 Y104 L105 Y108 F139 P02185 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTALTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFYSEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGY 5utd A 1.78 BS02 NO2 A 1 L29 H64 A68 Y107 L29 H64 A68 Y107 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTALTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFYSEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGY 5utm B 1.77 BS01 NAD B 1 G9 G11 R12 I13 D34 L35 R78 A96 T97 G98 F99 F100 T121 A122 C152 N316 Y320 G8 G10 R11 I12 D33 L34 R77 A95 T96 G97 F98 F99 T120 A121 C151 N315 Y319 1.2.1.- Q9ALW2 VVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNTLVKVVSWYDNEMSYTSQLVRTLEYFAKI 5uun B 1.45 BS01 GSH B 1 T56 N58 I86 Q91 F92 S103 K104 I105 E121 S122 T47 N49 I77 Q82 F83 S94 K95 I96 E112 S113 Q2G542 YVPPKVWKWDKANGGAFASVNRPVAGPTSERELPVGKHPFQVYSLGTPNGQKATIMLEELLQLGFSEAEYDAWLIKIFEGDQFTSGFVDINPNSKIPAMVDRSGPEPFRVFESGAILMHLAEKFGVFLPTSGPARAECLSWLFWQVGSAPFIGGGFGHFYNYAPIKIEYAIDRYAMETKRLFDVANRRLAESRYLAGDEYTIADLATYTWFGNIYRGEAYGEAATFLSMHEYEHVGRWVGEIDARPGVLRGRLVNSSKGLAERHDASDFDALPPESLQAIVKGF 5uun B 1.45 BS02 GSH B 2 F26 N30 T56 N58 K104 A158 P159 G162 G163 W219 Y229 F17 N21 T47 N49 K95 A149 P150 G153 G154 W210 Y220 Q2G542 YVPPKVWKWDKANGGAFASVNRPVAGPTSERELPVGKHPFQVYSLGTPNGQKATIMLEELLQLGFSEAEYDAWLIKIFEGDQFTSGFVDINPNSKIPAMVDRSGPEPFRVFESGAILMHLAEKFGVFLPTSGPARAECLSWLFWQVGSAPFIGGGFGHFYNYAPIKIEYAIDRYAMETKRLFDVANRRLAESRYLAGDEYTIADLATYTWFGNIYRGEAYGEAATFLSMHEYEHVGRWVGEIDARPGVLRGRLVNSSKGLAERHDASDFDALPPESLQAIVKGF 5uun B 1.45 BS03 GSH A 1 F160 R182 F151 R173 Q2G542 YVPPKVWKWDKANGGAFASVNRPVAGPTSERELPVGKHPFQVYSLGTPNGQKATIMLEELLQLGFSEAEYDAWLIKIFEGDQFTSGFVDINPNSKIPAMVDRSGPEPFRVFESGAILMHLAEKFGVFLPTSGPARAECLSWLFWQVGSAPFIGGGFGHFYNYAPIKIEYAIDRYAMETKRLFDVANRRLAESRYLAGDEYTIADLATYTWFGNIYRGEAYGEAATFLSMHEYEHVGRWVGEIDARPGVLRGRLVNSSKGLAERHDASDFDALPPESLQAIVKGF 5uun A 1.45 BS02 GSH A 2 T56 N58 I86 Q91 S103 K104 I105 P106 E121 S122 T49 N51 I79 Q84 S96 K97 I98 P99 E114 S115 Q2G542 SEYVPPKVWKWDKANGGAFASVNRPVAGPTSERELPVGKHPFQVYSLGTPNGQKATIMLEELLQLGFSEAEYDAWLIKIFEGDQFTSGFVDINPNSKIPAMVDRSGPEPFRVFESGAILMHLAEKFGVFLPTSGPARAECLSWLFWQVGSAPFIGGGFGHFYNYAPIKIEYAIDRYAMETKRLFDVANRRLAESRYLAGDEYTIADLATYTWFGNIYRGEAYGEAATFLSMHEYEHVGRWVGEIDARPGVLRGRLVNSSKGLAERHDASDFDALPPESLQAIVKGF 5uuo A 1.25 BS02 GSH A 2 T56 N58 I86 Q91 S103 K104 I105 E121 S122 V155 T48 N50 I78 Q83 S95 K96 I97 E113 S114 V147 Q2G542 EYVPPKVWKWDKANGGAFASVNRPVAGPTSERELPVGKHPFQVYSLGTPNGQKATIMLEELLQLGFSEAEYDAWLIKIFEGDQFTSGFVDINPNSKIPAMVDRSGPEPFRVFESGAILMHLAEKFGVFLPTSGPARAECLSWLFWQVGSAPFIGGGFGHFYNYAPIKIEYAIDRYAMETKRLFDVANRRLAESRYLAGDEYTIADLATYTWFGNIYRGEAYGEAATFLSMHEYEHVGRWVGEIDARPGVLRGRLVNSSKGLAERHDASDFDALPPESLQAIVKGF 5uur A 1.80 BS01 PAB A 1 V242 A243 V246 A267 V223 A224 V227 A248 2.5.1.15 D2UDM3 TSPRLDCAGRILTLDRPRVMGIVNVTPDSFTHTTVEAAVAHGLRLAEEGADLLDIGGEVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPAAGSAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 5uur A 1.80 BS02 PAB A 2 A47 H48 R51 A40 H41 R44 2.5.1.15 D2UDM3 TSPRLDCAGRILTLDRPRVMGIVNVTPDSFTHTTVEAAVAHGLRLAEEGADLLDIGGEVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPAAGSAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 5uur B 1.80 BS02 PAB B 1 T67 R68 G194 F195 K226 R227 T64 R65 G183 F184 K215 R216 2.5.1.15 D2UDM3 TSPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 5uur B 1.80 BS03 PAB B 2 S34 D35 G36 G37 S31 D32 G33 G34 2.5.1.15 D2UDM3 TSPRLDCAGRILTLDRPRVMGIVNVTPDSFSDGGTHTTVEAAVAHGLRLAEEGADLLDIGGESTRPGATAVPVEEELRRVIPVIERLVAQTALPLSVDTFKPEVMRAAVAAGAGMINDVQALRQPGALDAVADLRVPVVLMHMPAPHYDDVVAEVHRFLVERIFAAEMAGIDKRRLLIDPGFGFGKSTADNVQLLAHLPRLCELGVPVLAGLSRKRSIGELTGRELPEQRVAGSVAAHLLAAQRGALLLRVHDVAATVDALTVWQAVQAVP 5uw0 B 2.73 BS01 UDP B 1 G319 R320 V356 F480 L481 Y492 Y513 T514 E517 G318 R319 V355 F479 L480 Y491 Y512 T513 E516 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHQWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5uw0 C 2.73 BS01 U2F C 1 R20 G22 G23 I24 S26 H193 R199 R320 K326 V356 F480 L481 Y492 E509 P510 W511 G512 Y513 T514 E517 R19 G21 G22 I23 S25 H192 R198 R319 K325 V355 F479 L480 Y491 E508 P509 W510 G511 Y512 T513 E516 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHQWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5uw0 C 2.73 BS02 G6P C 1 Q283 N284 H286 K290 H500 R580 R583 R587 Q282 N283 H285 K289 H499 R579 R582 R586 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHQWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5uw1 B 3.26 BS01 GDU B 1 G23 G319 R320 K326 V356 F480 L481 Y492 Y513 T514 E517 G22 G318 R319 K325 V355 F479 L480 Y491 Y512 T513 E516 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHQWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5uw1 C 3.26 BS01 GDU C 1 G23 I24 H193 R199 G319 R320 K326 V356 F480 L481 Y492 Y513 T514 E517 G22 I23 H192 R198 G318 R319 K325 V355 F479 L480 Y491 Y512 T513 E516 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHQWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5uw4 C 2.98 BS01 GCS C 1 G23 H193 R199 N269 E509 P510 W511 G512 G22 H192 R198 N268 E508 P509 W510 G511 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHQWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5uw4 C 2.98 BS02 UDP C 1 R20 G22 G23 S26 R320 K326 F480 L481 Y492 Y513 T514 E517 R19 G21 G22 S25 R319 K325 F479 L480 Y491 Y512 T513 E516 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHQWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5ux1 A 1.50 BS01 FE A 1 E84 E137 E167 H170 E62 E115 E145 H148 Q3AMA5 IRWLAAPTSWSWVEQANAHPMEVLIDHAHCERKAAGAAVQMMFRYLCEPGLGEALSPLAREELEHFEQVLALIKARGRYLEPLPSPGYGADLARQIRKGEPQRMLDSFLVAGLIEARSHERMALLAEHSPDPQLRELYSDLLASEARHFGLYWVLCEQRYPRELIVERLEVLALAEVKALEGALTRPEDVRMHSCGVDVTQ 5ux1 A 1.50 BS02 FE A 2 E53 E84 H87 E167 E31 E62 H65 E145 Q3AMA5 IRWLAAPTSWSWVEQANAHPMEVLIDHAHCERKAAGAAVQMMFRYLCEPGLGEALSPLAREELEHFEQVLALIKARGRYLEPLPSPGYGADLARQIRKGEPQRMLDSFLVAGLIEARSHERMALLAEHSPDPQLRELYSDLLASEARHFGLYWVLCEQRYPRELIVERLEVLALAEVKALEGALTRPEDVRMHSCGVDVTQ 5ux1 B 1.50 BS02 FE B 2 E53 E84 H87 H170 E31 E62 H65 H148 Q3AMA5 IRWLAAPTSWSWVEQANAHPMEVLIDHAHCERKAAGAAVQMMFRYLCEPGLGEALSPLAREELEHFEQVLALIKARGRYLEPLPSPGYGADLARQIRKGEPQRMLDSFLVAGLIEARSHERMALLAEHSPDPQLRELYSDLLASEARHFGLYWVLCEQRYPRELIVERLEVLALAEVKALEGALTRPEDVRMHSCGVDVTQ 5ux2 A 1.99 BS01 FE A 1 E54 Q104 E109 E138 H141 E51 Q101 E106 E135 H138 4.1.99.5 A3Z6M0 LDFASAAYREAYSRINGVVIVGEGLANRHFQMLARRIPADRDELQRLGRMEGDHASAFVGCGRNLGVVADLPLARRLFQPLHDLFKRHDHDGNRAECLVIQGLIVECFAVAAYRHYLPVADAYARPITAAVMNDESEHLDYAETWLQRHFDQVKARVSAVVVEALPLTLAMLQSLAADMRQIGMDPVETLASFSELFREALESVGFEAVEARRLLMRAAA 5ux2 A 1.99 BS02 FE A 2 E26 E54 H57 E138 E23 E51 H54 E135 4.1.99.5 A3Z6M0 LDFASAAYREAYSRINGVVIVGEGLANRHFQMLARRIPADRDELQRLGRMEGDHASAFVGCGRNLGVVADLPLARRLFQPLHDLFKRHDHDGNRAECLVIQGLIVECFAVAAYRHYLPVADAYARPITAAVMNDESEHLDYAETWLQRHFDQVKARVSAVVVEALPLTLAMLQSLAADMRQIGMDPVETLASFSELFREALESVGFEAVEARRLLMRAAA 5ux2 B 1.99 BS02 FE B 2 E54 E109 E138 H141 E51 E106 E135 H138 4.1.99.5 A3Z6M0 LDFASAAYREAYSRINGVVIVGEGLANRHFQMLARRIPADRDELQRLGRMEGDHASAFVGCGRNLGVVADLPLARRLFQPLHDLFKRHDHDGNRAECLVIQGLIVECFAVAAYRHYLPVADAYARPITAAVMNDESEHLDYAETWLQRHFDQVKARVSAVVVEALPLTLAMLQSLAADMRQIGMDPVETLASFSELFREALESVGFEAVEARRLLMRA 5ux7 B 2.69 BS01 UDX B 1 R199 R320 K326 V356 F480 L481 Y492 E509 P510 Y513 T514 E517 R198 R319 K325 V355 F479 L480 Y491 E508 P509 Y512 T513 E516 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5ux7 C 2.69 BS01 UDX C 1 R20 G23 R199 G319 R320 K326 V356 F480 L481 Y492 T514 E517 R19 G22 R198 G318 R319 K325 V355 F479 L480 Y491 T513 E516 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5ux7 D 2.69 BS01 UDP D 1 G319 R320 K326 V356 F480 L481 Y492 G512 Y513 E517 G316 R317 K323 V353 F477 L478 Y489 G509 Y510 E514 2.4.1.11 P27472 SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA 5uxm A 1.54 BS01 PEP A 1 R108 P116 G265 D266 R267 K289 R320 H352 R105 P113 G262 D263 R264 K286 R317 H349 2.5.1.54 Q9I000 SWSPESWRAKPIQQQPEYPDAAHLARVEQTLAGYPPLVFAGEARELRRQFAEVTAGRAFLLQGGDCAESFAEFSAAKIRDTFKVLLQMAVVMTFAAGCPVVKVGRMAGQFAKPRSSGDETQNGVTLPAYRGDIVNGIGFDEKSRVPDPERLLQAYHQSTASLNLLRAFAQGGFADLHQVHRWNLDFIANSALAERYQQLADRIDETLAFMRACGLDSAPQLRETSFFTAHEALLLNYEEALTRRDSLTGEWYDCSAHMLWIGDRTRQIDGAHVEMLRGVGNPIGVKVGPSMDSEELIRLIDILNPDNDPGRLNLIVRMGADKVGDHLPRLIQAIQREGRQVLWSSDPMHGNTIKASSGYKTRDFARVLAEVRQFFEVHQAEGSYAGGIHIEMTGQNVTECIGGSRPITEDGLSDRYHTHCDPRLNADQSLELAFLIAETLKQVRR 5uxm A 1.54 BS02 TRP A 1 V93 K105 A177 L179 W185 Q223 E226 T227 V90 K102 A174 L176 W182 Q220 E223 T224 2.5.1.54 Q9I000 SWSPESWRAKPIQQQPEYPDAAHLARVEQTLAGYPPLVFAGEARELRRQFAEVTAGRAFLLQGGDCAESFAEFSAAKIRDTFKVLLQMAVVMTFAAGCPVVKVGRMAGQFAKPRSSGDETQNGVTLPAYRGDIVNGIGFDEKSRVPDPERLLQAYHQSTASLNLLRAFAQGGFADLHQVHRWNLDFIANSALAERYQQLADRIDETLAFMRACGLDSAPQLRETSFFTAHEALLLNYEEALTRRDSLTGEWYDCSAHMLWIGDRTRQIDGAHVEMLRGVGNPIGVKVGPSMDSEELIRLIDILNPDNDPGRLNLIVRMGADKVGDHLPRLIQAIQREGRQVLWSSDPMHGNTIKASSGYKTRDFARVLAEVRQFFEVHQAEGSYAGGIHIEMTGQNVTECIGGSRPITEDGLSDRYHTHCDPRLNADQSLELAFLIAETLKQVRR 5uxm A 1.54 BS03 CO A 1 C69 H352 R365 E394 D424 C66 H349 R362 E391 D421 2.5.1.54 Q9I000 SWSPESWRAKPIQQQPEYPDAAHLARVEQTLAGYPPLVFAGEARELRRQFAEVTAGRAFLLQGGDCAESFAEFSAAKIRDTFKVLLQMAVVMTFAAGCPVVKVGRMAGQFAKPRSSGDETQNGVTLPAYRGDIVNGIGFDEKSRVPDPERLLQAYHQSTASLNLLRAFAQGGFADLHQVHRWNLDFIANSALAERYQQLADRIDETLAFMRACGLDSAPQLRETSFFTAHEALLLNYEEALTRRDSLTGEWYDCSAHMLWIGDRTRQIDGAHVEMLRGVGNPIGVKVGPSMDSEELIRLIDILNPDNDPGRLNLIVRMGADKVGDHLPRLIQAIQREGRQVLWSSDPMHGNTIKASSGYKTRDFARVLAEVRQFFEVHQAEGSYAGGIHIEMTGQNVTECIGGSRPITEDGLSDRYHTHCDPRLNADQSLELAFLIAETLKQVRR 5uxn A 2.20 BS03 TYR A 1 A177 L179 W185 Q223 E226 T227 A174 L176 W182 Q220 E223 T224 2.5.1.54 Q9I000 SWSPESWRAKPIQQQPEYPDAAHLARVEQTLAGYPPLVFAGEARELRRQFAEVTAGRAFLLQGGDCAESFAEFSAAKIRDTFKVLLQMAVVMTFAAGCPVVKVGRMAGQFAKPRSSGDETQNGVTLPAYRGDIVNGIGFDEKSRVPDPERLLQAYHQSTASLNLLRAFAQGGFADLHQVHRWNLDFIANSALAERYQQLADRIDETLAFMRACGLDSAPQLRETSFFTAHEALLLNYEEALTRRDSLTGEWYDCSAHMLWIGDRTRQIDGAHVEMLRGVGNPIGVKVGPSMDSEELIRLIDILNPDNDPGRLNLIVRMGADKVGDHLPRLIQAIQREGRQVLWSSDPMHGNTIKASSGYKTRDFARVLAEVRQFFEVHQAEGSYAGGIHIEMTGQNVTECIGGSRPITEDGLSDRYHTHCDPRLNADQSLELAFLIAETLKQVRR 5uxo A 2.35 BS01 CO A 1 C69 H352 E394 D424 C66 H349 E391 D409 2.5.1.54 Q9I000 SWSPESWRAKPIQQQPEYPDAAHLARVEQTLAGYPPLVFAGEARELRRQFAEVTAGRAFLLQGGDCAESFAEFSAAKIRDTFKVLLQMAVVMTFAAGCPVVKVGRMAGQFAKPRSSGDETQNGVTLPAYRGDIVNGIGFDEKSRVPDPERLLQAYHQSTASLNLLRAFAQGGFADLHQVHRWNLDFIANSALAERYQQLADRIDETLAFMRACGLDSAPQLRETSFFTAHEALLLNYEEALTRRDSLTGEWYDCSAHMLWIGDRTRQIDGAHVEMLRGVGNPIGVKVGPSMDSEELIRLIDILNPDNDPGRLNLIVRMGADKVGDHLPRLIQAIQREGRQVLWSSDPMHGNTIKASSGYKTRDFARVLAEVRQFFEVHQAEGSYAGGIHIEMTGQNVTECIGRYHTHCDPRLNADQSLELAFLIAETLKQVRR 5uxo A 2.35 BS02 PEP A 1 R108 P116 G265 D266 R267 K289 R320 H352 E394 R105 P113 G262 D263 R264 K286 R317 H349 E391 2.5.1.54 Q9I000 SWSPESWRAKPIQQQPEYPDAAHLARVEQTLAGYPPLVFAGEARELRRQFAEVTAGRAFLLQGGDCAESFAEFSAAKIRDTFKVLLQMAVVMTFAAGCPVVKVGRMAGQFAKPRSSGDETQNGVTLPAYRGDIVNGIGFDEKSRVPDPERLLQAYHQSTASLNLLRAFAQGGFADLHQVHRWNLDFIANSALAERYQQLADRIDETLAFMRACGLDSAPQLRETSFFTAHEALLLNYEEALTRRDSLTGEWYDCSAHMLWIGDRTRQIDGAHVEMLRGVGNPIGVKVGPSMDSEELIRLIDILNPDNDPGRLNLIVRMGADKVGDHLPRLIQAIQREGRQVLWSSDPMHGNTIKASSGYKTRDFARVLAEVRQFFEVHQAEGSYAGGIHIEMTGQNVTECIGRYHTHCDPRLNADQSLELAFLIAETLKQVRR 5uyr A 3.45 BS01 BLA A 1 C13 M166 I178 Y190 Y195 S198 A199 P201 A204 Y208 R214 R246 V248 S249 H252 Y255 T264 V266 S280 H282 C2 M152 I164 Y176 Y181 S184 A185 P187 A190 Y194 R200 R232 V234 S235 H238 Y241 T250 V252 S266 H268 A0A0H2XCS3 VCAREPIHIPGLIQPYGVLLVIDPADGRIVQASTTAADLLGVPMAALLGMPYTQVLTLPEAQPFAVDDQPQHLMHAEVRFPQRATPPASAWVAAWHLYPQQWLVEMEPRDARVTLREAMPLLRSVERDPGIAEAAVRVAKGLRSLIGFDRVMIYRFDEEWNGDIIAEARKPELEAYLGLHYPASAIPAQARALYLRNRVRQIADVGYQPSPIQPTVHPQLGTPVDLSDVSLRSVSPVHLEYLANMGVTATLVASIVVNDALWGLISCHHYSPHFTNHAMRDVTDAVARTLAGRIGALQAVARARLESVLLTVREKLITDFNDAEHMTVELLDDMAPDLMDVVDADGVAIFHGNDISRHGTTPDVAALRRIRDHIESEHHEALREDAVGALHVDAIGEVFPELADLAPLAAGFIFVPLMPQSRSALLWTRREQIQQIKWAGNPRKSFDLWQQTVRGRARRWSPLHLESARSLRVLIELMERKRFQQDFTLLEASLSRLRDGVAIIERGTANAAHRLLFVNTAFADVCGSDVAELIGRELQTSDAPRANVELLQDALRNGRAAYVTLPLQVSAPVYRQFHLEPLPSPSGVTAHWLLQLR 5uyr B 3.45 BS01 BLA B 1 C13 I18 M166 Y168 I178 Y195 A199 I200 P201 A204 Y208 R214 R246 V248 S249 V251 H252 Y255 L256 T264 V266 S280 H282 C2 I7 M152 Y154 I164 Y181 A185 I186 P187 A190 Y194 R200 R232 V234 S235 V237 H238 Y241 L242 T250 V252 S266 H268 A0A0H2XCS3 VCAREPIHIPGLIQPYGVLLVIDPADGRIVQASTTAADLLGVPMAALLGMPYTQVLTLPEAQPFAVDDQPQHLMHAEVRFPQRATPPASAWVAAWHLYPQQWLVEMEPRDARVTLREAMPLLRSVERDPGIAEAAVRVAKGLRSLIGFDRVMIYRFDEEWNGDIIAEARKPELEAYLGLHYPASAIPAQARALYLRNRVRQIADVGYQPSPIQPTVHPQLGTPVDLSDVSLRSVSPVHLEYLANMGVTATLVASIVVNDALWGLISCHHYSPHFTNHAMRDVTDAVARTLAGRIGALQAVARARLESVLLTVREKLITDFNDAEHMTVELLDDMAPDLMDVVDADGVAIFHGNDISRHGTTPDVAALRRIRDHIESEHHEALREDAVGALHVDAIGEVFPELADLAPLAAGFIFVPLMPQSRSALLWTRREQIQQIKWAGNPFDLWQQTVRGRARRWSPLHLESARSLRVLIELMERKRFQQDFTLLEASLSRLRDGVAIIERGTANAAHRLLFVNTAFADVCGSDVAELIGRELQTLYASDAPRANVELLQDALRNGRAAYVTLPLQVSDGAPVYRQFHLEPLPSPSGVTAHWLLQLRD 5uys A 2.39 BS02 8QD A 1 A113 F114 N202 I205 I206 R239 D298 G301 A302 T306 V366 V482 V483 A83 F84 N172 I175 I176 R209 D265 G268 A269 T273 V333 V449 V450 1.14.14.19,1.14.14.32 P05093 LLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQA 5uys D 2.39 BS02 8QD D 1 A113 F114 N202 I205 I206 D298 G301 A302 T306 V366 A83 F84 N172 I175 I176 D268 G271 A272 T276 V336 1.14.14.19,1.14.14.32 P05093 LLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQ 5uz8 A 1.85 BS01 CA A 1 N2480 C2482 D2512 D2514 N2518 D2562 N216 C218 D248 D250 N254 D298 Q99PF4 DNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDIAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDISVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDV 5uz8 A 1.85 BS02 CA A 2 E2390 E2443 D2478 V2479 D2481 D2514 E126 E179 D214 V215 D217 D250 Q99PF4 DNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDIAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDISVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDV 5uz8 A 1.85 BS03 CA A 3 E2390 D2441 E2443 D2481 E126 D177 E179 D217 Q99PF4 DNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDIAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDISVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDV 5uz8 A 1.85 BS04 CA A 4 N2266 D2299 D2301 N2305 D2353 N2 D35 D37 N41 D89 Q99PF4 DNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDIAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDISVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDV 5uz8 A 1.85 BS05 CA A 5 N2373 N2375 D2405 D2407 F2411 D2456 N109 N111 D141 D143 F147 D192 Q99PF4 DNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDIAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDISVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDV 5uz8 A 1.85 BS06 CA A 6 E2284 E2340 D2371 I2372 D2374 N2375 D2407 E20 E76 D107 I108 D110 N111 D143 Q99PF4 DNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDIAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDISVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDV 5uz8 A 1.85 BS08 GSH A 1 D2441 E2443 K2444 D2481 C2482 D177 E179 K180 D217 C218 Q99PF4 DNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDIAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDISVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDV 5v8x A 2.95 BS02 MG A 1 I21 Q22 V24 V27 I19 Q20 V22 V25 1.2.1.- Q9ALW2 VKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISHSSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIAK 5v8x C 2.95 BS01 NAD C 1 N8 G9 F10 G11 R12 I13 D34 L35 R78 A96 T97 G98 F99 T121 A122 C152 N316 N6 G7 F8 G9 R10 I11 D32 L33 R76 A94 T95 G96 F97 T119 A120 C148 N311 1.2.1.- Q9ALW2 VKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISHSSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKI 5wn0 A 2.60 BS01 NUC C 1 R177 N222 N226 N229 T268 M270 M271 K276 V278 W280 R135 N180 N184 N187 T226 M228 M229 K234 V236 W238 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn0 A 2.60 BS02 NUC D 1 Y128 N174 R177 Y86 N132 R135 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn0 A 2.60 BS03 NUC E 1 G71 R73 A74 K78 E126 G127 Y269 M270 M271 G29 R31 A32 K36 E84 G85 Y227 M228 M229 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn1 A 2.30 BS01 NUC C 1 N222 N226 T268 M271 K276 V278 W280 N180 N184 T226 M229 K234 V236 W238 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn1 A 2.30 BS02 NUC D 1 Y128 Y171 N174 Y86 Y129 N132 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn1 A 2.30 BS03 NUC E 1 D70 G71 R73 A74 K78 K98 E126 G127 Y269 M270 M271 D28 G29 R31 A32 K36 K56 E84 G85 Y227 M228 M229 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn2 A 2.29 BS01 NUC C 1 N222 N226 T268 M271 K276 W280 N180 N184 T226 M229 K234 W238 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQQTKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGNLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn2 A 2.29 BS02 NUC D 1 Q96 Y128 Y171 R177 Q54 Y86 Y129 R135 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQQTKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGNLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn2 A 2.29 BS04 PGA D 1 Q96 Y171 N174 N210 N212 F266 L282 H309 Q54 Y129 N132 N168 N170 F224 L240 H267 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQQTKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGNLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn3 B 2.00 BS01 NUC C 1 N222 N226 M271 K276 V278 W280 N179 N183 M228 K233 V235 W237 3.1.-.-,4.2.99.18 P27695 29374164 LYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTAWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn3 B 2.00 BS02 NUC D 1 Y128 N174 N212 A266 T268 W280 L282 H309 Y85 N131 N169 A223 T225 W237 L239 H266 3.1.-.-,4.2.99.18 P27695 29374164 LYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTAWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn3 B 2.00 BS03 NUC E 1 G71 R73 A74 K78 K98 E126 G127 R177 K228 Y269 M270 M271 G28 R30 A31 K35 K55 E83 G84 R134 K185 Y226 M227 M228 3.1.-.-,4.2.99.18 P27695 29374164 LYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTAWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn4 B 2.10 BS02 NUC D 1 E96 Y128 Y171 N174 N212 A230 F266 W280 E54 Y86 Y129 N132 N170 A188 F224 W238 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn5 B 2.20 BS02 NUC D 1 E96 Y128 Y171 N174 R177 N212 F266 W280 L282 E54 Y86 Y129 N132 R135 N170 F224 W238 L240 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wn5 B 2.20 BS03 NUC E 1 G71 R73 A74 K78 K98 E126 G127 Y269 M270 G29 R31 A32 K36 K56 E84 G85 Y227 M228 3.1.-.-,4.2.99.18 P27695 29374164 ALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQAPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL 5wou A 1.55 BS01 III V 1 G15 L16 G17 L18 S19 I20 A21 G25 S26 T27 S39 R40 H71 V75 L78 K79 G16 L17 G18 L19 S20 I21 A22 G26 S27 T28 S40 R41 H72 V76 L79 K80 Q7KRY7 29378849 SRLEQYEIHIERTAAGLGLSIAGGKGSTPFKGDDDGIFISRVTEAGPADLAGLKVGDKVIKVNGIVVVDADHYQAVQVLKACGAVLVLVVQREVT 5wuw A 1.90 BS01 NAP A 1 G16 S18 R19 G20 I21 Y40 A41 A42 A66 D67 S68 N94 A95 G96 V97 I142 G143 Y158 K162 P188 G189 P190 V191 N196 G12 S14 R15 G16 I17 Y36 A37 A38 A62 D63 S64 N90 A91 G92 V93 I138 G139 Y154 K158 P184 G185 P186 V187 N192 A0A192ICX3 29396495 HPLQGKVAFVQGGSRGIGAAIVKRLASEGAAVAFTYAASADRAEAVASAVTTAGGKVLAIKADSADAAALQQAVRQAVSHFGNLDILVNNAGVLTLGGTEELALDDLDRMLAVNVRSVFVASQEAARHMNDGGRIIHIGSTNAERVPFGGAAVYAMSKSALVGLTKGMARDLGPRSITVNNVQPGPVDTEMNPDAGELADQLKQLMAIGRYGKDEEIAGFVAYLAGPQAGYITGASLSIDGGFSA 5wxi A 2.00 BS01 TRH A 1 I15 F18 G19 D20 L52 Y115 F185 Y187 A211 F249 V250 Q252 F255 R268 G269 E270 D271 S272 Y288 I14 F17 G18 D19 L51 Y114 F184 Y186 A210 F248 V249 Q251 F254 R267 G268 E269 D270 S271 Y287 E6MVV9 29440735 NTPPFVCWIFCKVIDNFGDIGVSWRLARVLHRELGWQVHLWTDDVSALRALCPDLPDVPCVHQDIHVRTWHSDAADIDTAPVPDVVIETFACDLPENVLHIIRRHKPLWLNWEYLSAEESNERLHLMPSPQEGVQKYFWFMGFSEKSGGLIRERDYCEAVRFDTEALRERLMLPEKNASEWLLFGYRSDVWAKWLEMWRQAGSPMTLLLAGTQIIDSLKQSGVIPQDALQNDGDVFQTASVRLVKIPFVPQQDFDQLLHLADCAVIRGEDSFVRAQLAGKPFFWHIYPQDENVHLDKLHAFWDKAHGFYTPETVSAHRRLSDDLNGGEALSATQRLECWQTLQQHQNGWRQGAEDWSRYLFGQPSAPEKLAAFVSKHQ 5wxi B 2.00 BS01 TRH B 1 I15 D16 F18 D20 Y115 F185 Y187 A211 F249 V250 Q252 F255 R268 G269 E270 D271 S272 Y288 I13 D14 F16 D17 Y112 F182 Y184 A208 F246 V247 Q249 F252 R265 G266 E267 D268 S269 Y285 E6MVV9 29440735 TPPFVCWIFCKVIDNFDIGVSWRLARVLHRELGWQVHLWTDDVSALRALCPDLPDVPCVHQDIHVRTWHSDAADIDTAPVPDVVIETFACDLPENVLHIIRRHKPLWLNWEYLSAEESNERLHLMPSPQEGVQKYFWFMGFSEKSGGLIRERDYCEAVRFDTEALRERLMLPEKNASEWLLFGYRSDVWAKWLEMWRQAGSPMTLLLAGTQIIDSLKQSGVIPQDALQNDGDVFQTASVRLVKIPFVPQQDFDQLLHLADCAVIRGEDSFVRAQLAGKPFFWHIYPQDENVHLDKLHAFWDKAHGFYTPETVSAHRRLSDDLNGGEALSATQRLECWQTLQQHQNGWRQGAEDWSRYLFGQPSAPEKLAAFVSKH 5wxk A 1.80 BS01 TYD A 1 N17 F18 G19 L52 F185 Y187 A211 F249 V250 Q252 F255 R268 G269 E270 D271 S272 N14 F15 G16 L49 F182 Y184 A208 F246 V247 Q249 F252 R265 G266 E267 D268 S269 E6MVV9 29440735 PPFVCWIFCKVIDNFGDIGVSWRLARVLHRELGWQVHLWTDDVSALRALCPDLPDVPCVHQDIHVRTWHSDAADIDTAPVPDVVIETFACDLPENVLHIIRRHKPLWLNWEYLSAEESNERLHLMPSPQEGVQKYFWFMGFSEKSGGLIRERDYCEAVRFDTEALRERLMLPEKNASEWLLFGYRSDVWAKWLEMWRQAGSPMTLLLAGTQIIDSLKQSGVIPQDALQNDGDVFQTASVRLVKIPFVPQQDFDQLLHLADCAVIRGEDSFVRAQLAGKPFFWHIYPQDENVHLDKLHAFWDKAHGFYTPETVSAHRRLSDDLNGGEALSATQRLECWQTLQQHQNGWRQGAEDWSRYLFGQPSAPEKLAAFVSKH 5x6i A 2.00 BS02 AP5 A 1 P9 G10 A11 G12 K13 G14 T15 T31 G32 F35 R36 I53 E57 L58 V59 T64 G85 F86 R88 Q92 R123 R127 T136 Y137 H138 F141 R160 R171 G197 Q199 I201 P9 G10 A11 G12 K13 G14 T15 T31 G32 F35 R36 I53 E57 L58 V59 T64 G85 F86 R88 Q92 R123 R127 T136 Y137 H138 F141 R160 R171 G197 Q199 I201 2.7.4.3 A0A063X902 MNLVLMGLPGAGKGTQGERIVEDYGTPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVPDEVTIGIVKERLGKDDCERGFLLDGFPRTVAQAEALEEILEEYGKPIDYVINIEVDKDVLMERLTGRRICSVCGTTYHLVFNPPKTPGICDKDGGELYQRADDNEETVSKRLEVNMKQTQPLLDFYSEKGYLANVNGQQDIQDVYADVKDLL 5x6i A 2.00 BS03 CA A 1 D116 D118 D116 D118 2.7.4.3 A0A063X902 MNLVLMGLPGAGKGTQGERIVEDYGTPHISTGDMFRAAMKEETPLGLEAKSYIDKGELVPDEVTIGIVKERLGKDDCERGFLLDGFPRTVAQAEALEEILEEYGKPIDYVINIEVDKDVLMERLTGRRICSVCGTTYHLVFNPPKTPGICDKDGGELYQRADDNEETVSKRLEVNMKQTQPLLDFYSEKGYLANVNGQQDIQDVYADVKDLL 5x6j A 2.10 BS02 AP5 A 1 P9 G10 A11 G12 K13 G14 T15 T31 G32 F35 R36 M53 A57 L58 V59 T64 G85 F86 R88 Q92 R123 R127 S136 Y137 H138 F141 R160 R171 K199 I201 P9 G10 A11 G12 K13 G14 T15 T31 G32 F35 R36 M53 A57 L58 V59 T64 G85 F86 R88 Q92 R123 R127 S136 Y137 H138 F141 R160 R171 K199 I201 2.7.4.3 P84139 MNIVLMGLPGAGKGTQADRIVEKYGIPHISTGDMFRAAIQEGTELGVKAKSFMDQGALVPDEVTIGIVRERLSKSDCDNGFLLDGFPRTVPQAEALDQLLADMGRKIEHVLNIQVEKEELIARLTGRRICKVCGTSYHLLFNPPQVEGKCDKDGGELYQRADDNPDTVTNRLEVNMNQTAPLLAFYDSKEVLVNINGQKDIKDVFKDLDVILQ 5x6k A 1.99 BS01 AP5 A 1 P17 G18 S19 G20 K21 G22 T23 S39 G40 L43 R44 M61 E65 L66 V67 G94 Y95 R97 Q101 R128 R132 R138 R149 L177 V179 P9 G10 S11 G12 K13 G14 T15 S31 G32 L35 R36 M53 E57 L58 V59 G86 Y87 R89 Q93 R120 R124 R130 R141 L169 V171 KIIFVVGGPGSGKGTQCEKVVAKYGYTHLSSGDLLRAEVSSGSERGKQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGYLIDGYPREVKQGEEFEKKIGKPCLLLYVDAKGETMVKRLMKRGETSGRADDNEETIKKRLDLYYKATEPVIAFYEGRGIVRKVDSELPVDEVFKQVSTAIDAL 5x6l A 1.86 BS01 AP5 A 1 G16 P17 G18 S19 G20 K21 G22 T23 S39 G40 L43 R44 M61 E65 L66 V67 V72 G94 Y95 R97 Q101 R128 R132 R138 R149 S175 L177 V179 G9 P10 G11 S12 G13 K14 G15 T16 S32 G33 L36 R37 M54 E58 L59 V60 V65 G87 Y88 R90 Q94 R121 R125 R131 R142 S168 L170 V172 AKIIFVVGGPGSGKGTQCEKIVAKYGYTHLSSGDLLRAEVSSGSERGKQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGYLIDGYPREVKQGEEFEKKIGKPCLLLYVDAKGETMVKRLMKRGETSGRADDNEETIKKRLDLYYKATEPVIAFYEGRGIVRKVDSELPVDEVFKQVSTAIDAL 5x6y A 2.10 BS01 SAM A 1 G210 Y211 I229 E230 K231 G470 D471 A472 S488 L489 N491 N494 G207 Y208 I226 E227 K228 G454 D455 A456 S472 L473 N475 N478 2.7.7.50 PDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6y A 2.10 BS02 SAM A 2 L269 Y285 G287 A288 Y289 P290 A291 H293 F307 D308 P309 K310 E333 F334 D359 T360 W361 F369 L253 Y269 G271 A272 Y273 P274 A275 H277 F291 D292 P293 K294 E317 F318 D343 T344 W345 F353 2.7.7.50 PDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6y B 2.10 BS01 SAM B 1 G210 I229 E230 K231 G470 D471 A472 Y487 S488 L489 N491 N494 G207 I226 E227 K228 G369 D370 A371 Y386 S387 L388 N390 N393 2.7.7.50 PDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVLLCLDTFMLSTSMNILPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKELNMFQNSKLSVIDLIDRTSIDVRLISVSHLLALLPMRAFFHKKGSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6y C 2.10 BS01 SAM C 1 G210 Y211 I229 E230 K231 G470 D471 A472 Y487 S488 L489 N491 N494 W554 G204 Y205 I223 E224 K225 G449 D450 A451 Y466 S467 L468 N470 N473 W527 2.7.7.50 CIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6y C 2.10 BS02 SAM C 2 L269 Y285 G287 Y289 P290 A291 H293 F307 D308 P309 K310 E333 F334 D359 T360 W361 L248 Y264 G266 Y268 P269 A270 H272 F286 D287 P288 K289 E312 F313 D338 T339 W340 2.7.7.50 CIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6z C 2.10 BS01 GTP C 1 Q616 K627 Y645 R648 S702 G703 H704 W722 N747 K748 W758 H759 Q592 K603 Y621 R624 S678 G679 H680 W698 N723 K724 W734 H735 2.7.7.50 DYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6z C 2.10 BS02 GDP C 1 D50 M53 S54 E134 V137 D46 M49 S50 E130 V133 2.7.7.50 DYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6z C 2.10 BS03 GDP D 1 Y73 R77 Y645 Y69 R73 Y621 2.7.7.50 DYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6z A 2.10 BS01 GTP A 1 Q616 P622 K627 Y645 R648 I701 S702 G703 H704 W722 M726 D746 W758 H759 Q599 P605 K610 Y628 R631 I684 S685 G686 H687 W705 M709 D729 W741 H742 2.7.7.50 NPDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVINEMHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6z A 2.10 BS03 GDP B 1 R77 H641 R75 H624 2.7.7.50 NPDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVINEMHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6z D 2.10 BS01 GDP C 1 Y73 R77 H641 K748 Y73 R77 H631 K738 2.7.7.50 MSNPDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIYVMHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNPTGRRWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6z D 2.10 BS02 GTP D 1 Q616 Y645 R648 N700 G703 H704 W722 M726 N747 K748 W758 H759 Q606 Y635 R638 N690 G693 H694 W712 M716 N737 K738 W748 H749 2.7.7.50 MSNPDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIYVMHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNPTGRRWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x6z B 2.10 BS01 GTP B 1 Q616 P622 Y645 R648 I701 S702 G703 H704 W722 M726 D746 N747 K748 W758 H759 Q591 P597 Y620 R623 I676 S677 G678 H679 W697 M701 D721 N722 K723 W733 H734 2.7.7.50 DYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIMHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x70 A 3.30 BS01 NUC E 1 Y73 R77 K627 H641 Y645 H704 W758 Y69 R73 K605 H619 Y623 H682 W736 2.7.7.50 DYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x70 A 3.30 BS02 NUC G 1 D50 V137 D46 V133 2.7.7.50 DYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x70 B 3.30 BS01 NUC E 1 K46 D50 M53 S54 E134 V137 K43 D47 M50 S51 E131 V134 2.7.7.50 PDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x70 B 3.30 BS02 NUC G 1 Y73 R77 E642 Y70 R74 E621 2.7.7.50 PDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x71 A 2.57 BS01 5GP A 1 Q616 P622 I701 S702 G703 H704 W722 D746 K748 W758 H759 Q611 P617 I696 S697 G698 H699 W717 D741 K743 W753 H754 2.7.7.50 PDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVINELVLKVKYVMHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNPTGRRWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x71 B 2.57 BS01 5GP B 1 Q616 P622 I701 S702 G703 H704 W722 M726 N747 W758 H759 Q610 P616 I695 S696 G697 H698 W716 M720 N741 W752 H753 2.7.7.50 DYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVINELVLKVKYVMHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNPTGRRWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI 5x7u A 2.50 BS01 MG A 1 D23 N25 D27 S29 D31 D20 N22 D24 S26 D28 D1CE96 28809106 DPTWYKDAIIYEVGVRCFFDSNNDGSGDIPGLTAKLDYIESLGVTAIWLLPFYASPLKDGGYDISDYRSLHPDFGTIEDFKVFLDEAHRRGIRVITELVLNHTSDQHQWFREARSNPNSPYRDYYVWSDTDDKYKDARIIFIDTERSNWTWDQEAGKYYWHRFFSHQPDLNYDNPKVQQEILDIVGYWLDMGVDGLRLDAVPYLYEREGTNCENLPETHEFLKKLRKFVDDNWPNRMLLAEANQWPEDVVAYFGNGDECHMAYHFPIMPRMYMALRREDRHPITEILRRTPPIPETCQWALFLRNHDELTLEMVTDEERDYMYHEYAKDPRMRLNLGIRRRLAPLLDNSERRIQLMHLLLFTLPGTPIIYYGDEIGMGDNVYLGDRDGVRTPMQWSGDRNAGFSRANPQALYLPPIRDPVFTYEAVNVEAQEQVPTSLLNWMKRTIQIRKKYPVFGRGSIRFLQPSNRAVLAYIRQYQDTTILCACNLSRFCQAAELDLSDFKGLYPVELYGKTVFPQIGELPYLLTFGPHVFYWFELKPQEQLPH 5x7u A 2.50 BS02 MG A 2 R283 T287 R291 R471 R280 T284 R288 R468 D1CE96 28809106 DPTWYKDAIIYEVGVRCFFDSNNDGSGDIPGLTAKLDYIESLGVTAIWLLPFYASPLKDGGYDISDYRSLHPDFGTIEDFKVFLDEAHRRGIRVITELVLNHTSDQHQWFREARSNPNSPYRDYYVWSDTDDKYKDARIIFIDTERSNWTWDQEAGKYYWHRFFSHQPDLNYDNPKVQQEILDIVGYWLDMGVDGLRLDAVPYLYEREGTNCENLPETHEFLKKLRKFVDDNWPNRMLLAEANQWPEDVVAYFGNGDECHMAYHFPIMPRMYMALRREDRHPITEILRRTPPIPETCQWALFLRNHDELTLEMVTDEERDYMYHEYAKDPRMRLNLGIRRRLAPLLDNSERRIQLMHLLLFTLPGTPIIYYGDEIGMGDNVYLGDRDGVRTPMQWSGDRNAGFSRANPQALYLPPIRDPVFTYEAVNVEAQEQVPTSLLNWMKRTIQIRKKYPVFGRGSIRFLQPSNRAVLAYIRQYQDTTILCACNLSRFCQAAELDLSDFKGLYPVELYGKTVFPQIGELPYLLTFGPHVFYWFELKPQEQLPH 5x7u A 2.50 BS03 MG A 3 S352 R355 H534 S349 R352 H531 D1CE96 28809106 DPTWYKDAIIYEVGVRCFFDSNNDGSGDIPGLTAKLDYIESLGVTAIWLLPFYASPLKDGGYDISDYRSLHPDFGTIEDFKVFLDEAHRRGIRVITELVLNHTSDQHQWFREARSNPNSPYRDYYVWSDTDDKYKDARIIFIDTERSNWTWDQEAGKYYWHRFFSHQPDLNYDNPKVQQEILDIVGYWLDMGVDGLRLDAVPYLYEREGTNCENLPETHEFLKKLRKFVDDNWPNRMLLAEANQWPEDVVAYFGNGDECHMAYHFPIMPRMYMALRREDRHPITEILRRTPPIPETCQWALFLRNHDELTLEMVTDEERDYMYHEYAKDPRMRLNLGIRRRLAPLLDNSERRIQLMHLLLFTLPGTPIIYYGDEIGMGDNVYLGDRDGVRTPMQWSGDRNAGFSRANPQALYLPPIRDPVFTYEAVNVEAQEQVPTSLLNWMKRTIQIRKKYPVFGRGSIRFLQPSNRAVLAYIRQYQDTTILCACNLSRFCQAAELDLSDFKGLYPVELYGKTVFPQIGELPYLLTFGPHVFYWFELKPQEQLPH 5x7u A 2.50 BS04 MG A 4 N104 D172 Y206 L207 E209 N101 D169 Y203 L204 E206 D1CE96 28809106 DPTWYKDAIIYEVGVRCFFDSNNDGSGDIPGLTAKLDYIESLGVTAIWLLPFYASPLKDGGYDISDYRSLHPDFGTIEDFKVFLDEAHRRGIRVITELVLNHTSDQHQWFREARSNPNSPYRDYYVWSDTDDKYKDARIIFIDTERSNWTWDQEAGKYYWHRFFSHQPDLNYDNPKVQQEILDIVGYWLDMGVDGLRLDAVPYLYEREGTNCENLPETHEFLKKLRKFVDDNWPNRMLLAEANQWPEDVVAYFGNGDECHMAYHFPIMPRMYMALRREDRHPITEILRRTPPIPETCQWALFLRNHDELTLEMVTDEERDYMYHEYAKDPRMRLNLGIRRRLAPLLDNSERRIQLMHLLLFTLPGTPIIYYGDEIGMGDNVYLGDRDGVRTPMQWSGDRNAGFSRANPQALYLPPIRDPVFTYEAVNVEAQEQVPTSLLNWMKRTIQIRKKYPVFGRGSIRFLQPSNRAVLAYIRQYQDTTILCACNLSRFCQAAELDLSDFKGLYPVELYGKTVFPQIGELPYLLTFGPHVFYWFELKPQEQLPH 5xfm A 2.30 BS01 CA A 1 E179 E457 E463 E164 E442 E448 A0A1H5YQC4 28804002 HMELQDVVVKGPDEKLQLAVFVQNETKPCYSVSYNGKTMLEKSPLGMNTNIGDFTKNLKLTGHSVDKIDTVYQQTRIKVSNVHYRANELTCHLENEQGQKLGVIFRVSDNDVAFRYTLPHQGGKASVTVKEEQTGFRFPEQTTTFLCPQSDAMIGWKRTKPSYEEEYKADAPMSDRSQYGHGYTFPCLFRIGNDGWVLVSETGVDSRYCGSRLSDVSEGNLYTVAFPMAEENNGNGTVAPAFALPGATPWRTITVGDHLKPIVETTVPWDVVSPLYETKHDYRFGRGTWSWILWQDGSINYDDQVRYIDFASAMGYEYALIDNWWDTRIGHQRMKSLVEYARDKGVELFLWYSSSGYWNDIEQGPVNRMDNAIIRKREMKWLQSLGVKGIKVDFFGGDKQETMRLYEDILSDADDHGLMVIFHGCTLPRGWERMYPNYVGSEAVLASENMVFNQHFCDEEAFNTCLHPFIRNTVGSMEFGGCLLNKRLNRNNDGGTTRRTTDVFQLATTVLLQNPVQNFALAPNNLKDVPAVCMDFMKRVPTTWDETRFVDGYPGKYVVLARRQGDTWYLAAVNAGKEPLKLKLDLEMFAGKTVALYKDDKKGEPELTSLKVKENGKVQLEIRPQGGILCIK 5xgx A 2.33 BS01 ZN A 1 H71 H73 E166 D293 H66 H68 E161 D288 3.4.19.- Q484B6 28723955 TMLILLCNVNIYAPNPLGIKDVLIAGNKIAAIYDHGQGEITIPKQWPVKVINFDGAILTPGFIDSHAHITGGGGQAGFATQVPPVGLTEFTHAGVTTVVGLLGTDDTTRSTENLLSRVYGLREEGLSAYCWTGGYHFPLTTITGSAKSDIAFLEPVIGIGEFAISDHRSSQPTFEEVIRLASETHVAGLITGKAGVIHFHLGDGERRLELIERAIRETELPARVFNPTHVNRNKPLFEDSCKLLSKGCHIDLTAFPAGTAQPGWEACDAIEMAVERQLPLEQITLSSDGGGCLPCMDFGRASTLGETLVATLNKGLSLETVLPMLTSNVANILRFKNKGQIAVGFDADLLVMNEKYEITDVMAQGVWHKQNNQTMIKGTFE 5xgx A 2.33 BS02 ZN A 2 E166 H205 H234 E161 H200 H229 3.4.19.- Q484B6 28723955 TMLILLCNVNIYAPNPLGIKDVLIAGNKIAAIYDHGQGEITIPKQWPVKVINFDGAILTPGFIDSHAHITGGGGQAGFATQVPPVGLTEFTHAGVTTVVGLLGTDDTTRSTENLLSRVYGLREEGLSAYCWTGGYHFPLTTITGSAKSDIAFLEPVIGIGEFAISDHRSSQPTFEEVIRLASETHVAGLITGKAGVIHFHLGDGERRLELIERAIRETELPARVFNPTHVNRNKPLFEDSCKLLSKGCHIDLTAFPAGTAQPGWEACDAIEMAVERQLPLEQITLSSDGGGCLPCMDFGRASTLGETLVATLNKGLSLETVLPMLTSNVANILRFKNKGQIAVGFDADLLVMNEKYEITDVMAQGVWHKQNNQTMIKGTFE 5xgx A 2.33 BS03 DAS A 1 H73 G78 Q80 T109 Y140 E166 H205 C297 H68 G73 Q75 T104 Y135 E161 H200 C292 3.4.19.- Q484B6 28723955 TMLILLCNVNIYAPNPLGIKDVLIAGNKIAAIYDHGQGEITIPKQWPVKVINFDGAILTPGFIDSHAHITGGGGQAGFATQVPPVGLTEFTHAGVTTVVGLLGTDDTTRSTENLLSRVYGLREEGLSAYCWTGGYHFPLTTITGSAKSDIAFLEPVIGIGEFAISDHRSSQPTFEEVIRLASETHVAGLITGKAGVIHFHLGDGERRLELIERAIRETELPARVFNPTHVNRNKPLFEDSCKLLSKGCHIDLTAFPAGTAQPGWEACDAIEMAVERQLPLEQITLSSDGGGCLPCMDFGRASTLGETLVATLNKGLSLETVLPMLTSNVANILRFKNKGQIAVGFDADLLVMNEKYEITDVMAQGVWHKQNNQTMIKGTFE 5xgx A 2.33 BS04 DLY A 1 Y140 R173 H205 H234 R237 F260 Q266 D293 C297 L298 P299 Y135 R168 H200 H229 R232 F255 Q261 D288 C292 L293 P294 3.4.19.- Q484B6 28723955 TMLILLCNVNIYAPNPLGIKDVLIAGNKIAAIYDHGQGEITIPKQWPVKVINFDGAILTPGFIDSHAHITGGGGQAGFATQVPPVGLTEFTHAGVTTVVGLLGTDDTTRSTENLLSRVYGLREEGLSAYCWTGGYHFPLTTITGSAKSDIAFLEPVIGIGEFAISDHRSSQPTFEEVIRLASETHVAGLITGKAGVIHFHLGDGERRLELIERAIRETELPARVFNPTHVNRNKPLFEDSCKLLSKGCHIDLTAFPAGTAQPGWEACDAIEMAVERQLPLEQITLSSDGGGCLPCMDFGRASTLGETLVATLNKGLSLETVLPMLTSNVANILRFKNKGQIAVGFDADLLVMNEKYEITDVMAQGVWHKQNNQTMIKGTFE 5xgx B 2.33 BS03 DAS B 1 H73 G77 G78 Q80 G108 T109 Y140 E166 R173 G296 C297 P299 H68 G72 G73 Q75 G103 T104 Y135 E161 R168 G291 C292 P294 3.4.19.- Q484B6 28723955 TMLILLCNVNIYAPNPLGIKDVLIAGNKIAAIYDHGQGEITIPKQWPVKVINFDGAILTPGFIDSHAHITGGGGQAGFATQVPPVGLTEFTHAGVTTVVGLLGTDDTTRSTENLLSRVYGLREEGLSAYCWTGGYHFPLTTITGSAKSDIAFLEPVIGIGEFAISDHRSSQPTFEEVIRLASETHVAGLITGKAGVIHFHLGDGERRLELIERAIRETELPARVFNPTHVNRNKPLFEDSCKLLSKGCHIDLTAFPAGTAQPGWEACDAIEMAVERQLPLEQITLSSDGGGCLPCMDFGRASTLGETLVATLNKGLSLETVLPMLTSNVANILRFKNKGQIAVGFDADLLVMNEKYEITDVMAQGVWHKQNNQTMIKGTFE 5xgx B 2.33 BS04 DLY B 1 R173 H205 H234 R237 F260 L298 P299 R168 H200 H229 R232 F255 L293 P294 3.4.19.- Q484B6 28723955 TMLILLCNVNIYAPNPLGIKDVLIAGNKIAAIYDHGQGEITIPKQWPVKVINFDGAILTPGFIDSHAHITGGGGQAGFATQVPPVGLTEFTHAGVTTVVGLLGTDDTTRSTENLLSRVYGLREEGLSAYCWTGGYHFPLTTITGSAKSDIAFLEPVIGIGEFAISDHRSSQPTFEEVIRLASETHVAGLITGKAGVIHFHLGDGERRLELIERAIRETELPARVFNPTHVNRNKPLFEDSCKLLSKGCHIDLTAFPAGTAQPGWEACDAIEMAVERQLPLEQITLSSDGGGCLPCMDFGRASTLGETLVATLNKGLSLETVLPMLTSNVANILRFKNKGQIAVGFDADLLVMNEKYEITDVMAQGVWHKQNNQTMIKGTFE 5xu8 A 1.81 BS01 DX4 A 1 G268 L269 C276 N279 S280 Q283 Y558 T559 A560 F573 D575 S576 G5 L6 C13 N16 S17 Q20 Y286 T287 A288 F301 D303 S304 3.4.19.12 O75604 29449607 QGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVNLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELA 5xvr A 1.63 BS01 TRH A 1 F18 G19 N20 L52 Y115 F185 Y187 A211 F249 V250 Q252 F255 R268 G269 E270 D271 S272 Y288 F20 G21 N22 L54 Y117 F187 Y189 A213 F251 V252 Q254 F257 R270 G271 E272 D273 S274 Y290 E6MVV9 29440735 SHMNTPPFVCWIFCKVIDNFGNIGVSWRLARVLHRELGWQVHLWTDDVSALRALCPDLPDVPCVHQDIHVRTWHSDAADIDTAPVPDVVIETFACDLPENVLHIIRRHKPLWLNWEYLSAEESNERLHLMPSPQEGVQKYFWFMGFSEKSGGLIRERDYCEAVRFDTEALRERLMLPEKNASEWLLFGYRSDVWAKWLEMWRQAGSPMTLLLAGTQIIDSLKQSGVIPQDALQNDGDVFQTASVRLVKIPFVPQQDFDQLLHLADCAVIRGEDSFVRAQLAGKPFFWHIYPQDENVHLDKLHAFWDKAHGFYTPETVSAHRRLSDDLNGGEALSATQRLECWQTLQQHQNGWRQGAEDWSRYLFGQPSAPEKLAAFVSKHQ 5xwd A 2.89 BS01 ZN A 1 Q252 H566 Q249 H563 2.7.10.1 P00533 29462206 KKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPT 5xwd A 2.89 BS02 ZN A 2 D279 H280 D276 H277 2.7.10.1 P00533 29462206 KKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPT 5xwd A 2.89 BS03 ZN A 3 D369 R390 H394 D366 R387 H391 2.7.10.1 P00533 29462206 KKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPT 5xwd A 2.89 BS04 ZN A 4 D392 R427 D389 R424 2.7.10.1 P00533 29462206 KKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPT 5xwd A 2.89 BS05 ZN A 5 E320 H334 E317 H331 2.7.10.1 P00533 29462206 KKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPT 5xwd A 2.89 BS07 ZN A 7 Q252 D553 H566 Q249 D550 H563 2.7.10.1 P00533 29462206 KKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPT 5xwd H 2.89 BS01 ZN H 1 D74 S76 D73 S75 29462206 VQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARLPMVTMSFDYWGQGTLVTVSS 5xwd H 2.89 BS02 ZN H 2 R99 D108 R98 D107 29462206 VQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARLPMVTMSFDYWGQGTLVTVSS 5xwd D 2.89 BS01 ZN D 1 S2 H97 S1 H96 29462206 SYVLTQPPSVSVAPGKTARITCGGNNIGSKSVHWYQQKPGQAPVLVIYYDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHVVFGGGTKLTVL 5yb2 E 3.80 BS01 III H 1 L11 E15 Q18 Q22 V25 I28 K29 Q32 L36 L11 E15 Q18 Q22 V25 I28 K29 Q32 L36 Q1HMR5 SGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb2 E 3.80 BS02 III G 1 N9 R12 A16 Q17 H19 L20 L23 W26 G27 Q30 N9 R12 A16 Q17 H19 L20 L23 W26 G27 Q30 Q1HMR5 SGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb2 D 3.80 BS01 III G 1 I14 E15 Q18 Q22 V25 I28 K29 Q32 L36 I14 E15 Q18 Q22 V25 I28 K29 Q32 L36 Q1HMR5 SGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb2 F 3.80 BS01 III H 1 N9 A16 Q17 H19 L20 L23 W26 G27 Q30 N8 A15 Q16 H18 L19 L22 W25 G26 Q29 Q1HMR5 GIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb2 F 3.80 BS02 III I 1 L11 E15 Q18 V25 K29 Q32 L36 L10 E14 Q17 V24 K28 Q31 L35 Q1HMR5 GIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb2 A 3.80 BS01 III J 1 E15 Q18 Q22 V25 I28 K29 Q32 L36 E15 Q18 Q22 V25 I28 K29 Q32 L36 Q1HMR5 SGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb2 A 3.80 BS02 III L 1 N9 A16 H19 L20 L23 W26 G27 N9 A16 H19 L20 L23 W26 G27 Q1HMR5 SGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb2 C 3.80 BS01 III K 1 N9 A13 A16 Q17 H19 L20 L23 W26 G27 Q30 N8 A12 A15 Q16 H18 L19 L22 W25 G26 Q29 Q1HMR5 GIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb2 C 3.80 BS02 III L 1 L11 E15 Q18 V25 I28 K29 Q32 L10 E14 Q17 V24 I27 K28 Q31 Q1HMR5 GIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb2 M 3.80 BS01 III P 1 L11 Q18 Q22 V25 I28 K29 Q32 L36 L11 Q18 Q22 V25 I28 K29 Q32 L36 Q1HMR5 SGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb3 D 2.04 BS01 III G 1 Q52 Q56 I62 K63 Q66 L70 Q18 Q22 I28 K29 Q32 L36 Q1HMR5 SGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb3 F 2.04 BS02 III I 1 L45 Q52 I62 K63 Q66 L70 L10 Q17 I27 K28 Q31 L35 Q1HMR5 GIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yb4 E 2.50 BS01 III H 1 L45 Q52 Q56 I62 K63 Q66 L11 Q18 Q22 I28 K29 Q32 SGIVQQQNNLLRAIKAQQHLLQRTVWGIKQLQARIL 5yb4 E 2.50 BS02 III G 1 N43 A47 A50 H53 L54 R57 W60 G61 Q64 L65 N9 A13 A16 H19 L20 R23 W26 G27 Q30 L31 SGIVQQQNNLLRAIKAQQHLLQRTVWGIKQLQARIL 5yb4 D 2.50 BS01 III G 1 Q52 Q56 V59 I62 Q66 Q18 Q22 V25 I28 Q32 SGIVQQQNNLLRAIKAQQHLLQRTVWGIKQLQARIL 5yb4 D 2.50 BS02 III I 1 N43 R46 A47 A50 H53 L54 R57 W60 G61 Q64 L65 N9 R12 A13 A16 H19 L20 R23 W26 G27 Q30 L31 SGIVQQQNNLLRAIKAQQHLLQRTVWGIKQLQARIL 5yb4 F 2.50 BS02 III I 1 Q52 Q56 I62 K63 Q66 Q17 Q21 I27 K28 Q31 GIVQQQNNLLRAIKAQQHLLQRTVWGIKQLQARIL 5ys9 A 2.50 BS01 FAD A 1 F160 M162 T163 G168 S169 W200 G202 N261 V450 T453 W454 D457 N459 V460 L463 F153 M155 T156 G161 S162 W193 G195 N254 V443 T446 W447 D450 N452 V453 L456 1.3.3.6 O74936 29429324 ANVEIDGKQYNTFTEPPKALAGERAKVKFPIKDMTEFLHGGEENVTMIERLMTELERDPVLNVSGDYDMPKEQLRETAVARIAALSGHWKKDTEKEALLRSQLHGIVDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKGFYGCFAMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLVDGKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMKYAKVSSTGKVSQPPLAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGTTPGQPETKIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGKAIVDLKELFASSAGLKAFTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNVLCLSMGRGLIQSCLGHRKGKPLGSSVGYLANKGLEQATLSGRDLKDPKVLIEAWEKVANGAIQRATDKFVELTKGGLSPDQAFEELSQQRFQCAKIHTRKHLVTAFYERINASAKADVKPYLINLANLFTLWSIEEDSGLFLREGFLQPKDIDQVTELVNHYCKEVRDQVAGYTDAFGLSDWFINAPIGNYDGDVYKHYFAKVNQQNPAQNPRPPYYESTLRPFLFREDEDDDICELDE 5ys9 A 2.50 BS02 FAD B 1 R331 Q333 F334 I345 Y348 R354 Q428 A429 G431 G432 Y435 R324 Q326 F327 I338 Y341 R347 Q421 A422 G424 G425 Y428 1.3.3.6 O74936 29429324 ANVEIDGKQYNTFTEPPKALAGERAKVKFPIKDMTEFLHGGEENVTMIERLMTELERDPVLNVSGDYDMPKEQLRETAVARIAALSGHWKKDTEKEALLRSQLHGIVDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKGFYGCFAMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLVDGKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMKYAKVSSTGKVSQPPLAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGTTPGQPETKIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGKAIVDLKELFASSAGLKAFTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNVLCLSMGRGLIQSCLGHRKGKPLGSSVGYLANKGLEQATLSGRDLKDPKVLIEAWEKVANGAIQRATDKFVELTKGGLSPDQAFEELSQQRFQCAKIHTRKHLVTAFYERINASAKADVKPYLINLANLFTLWSIEEDSGLFLREGFLQPKDIDQVTELVNHYCKEVRDQVAGYTDAFGLSDWFINAPIGNYDGDVYKHYFAKVNQQNPAQNPRPPYYESTLRPFLFREDEDDDICELDE 5z6o A 1.70 BS01 CA A 1 V181 D204 V181 D204 3.4.21.64 9184139 ANVVQRNSPSWGLSRISSKKSGATDYVYDSTAGEGIVIYGVDTGIDIGHADFGGRAEWGTNTADNDDTDGNGHGTHTASTAAGSKFGVAKKASVVAVKVLGADGSGTNSQVIAGMDWAVKDSKSRGATGKSVMNMSLGGAYSRAMNDAAANVVRSGVFLSVAAGNEAQDASNSSPASAPNVCTIAASTNSDGSASFTNFGSVVDLYAPGKDITAAYPGGGSKTLSGTSMAAPHVAGAAAYLMALEGTTTSSACARIVQDAITKISGAPKGTTTKLLYNGING 5z6o A 1.70 BS02 PMS A 1 H73 S136 N165 G226 S228 H73 S136 N165 G226 S228 3.4.21.64 9184139 ANVVQRNSPSWGLSRISSKKSGATDYVYDSTAGEGIVIYGVDTGIDIGHADFGGRAEWGTNTADNDDTDGNGHGTHTASTAAGSKFGVAKKASVVAVKVLGADGSGTNSQVIAGMDWAVKDSKSRGATGKSVMNMSLGGAYSRAMNDAAANVVRSGVFLSVAAGNEAQDASNSSPASAPNVCTIAASTNSDGSASFTNFGSVVDLYAPGKDITAAYPGGGSKTLSGTSMAAPHVAGAAAYLMALEGTTTSSACARIVQDAITKISGAPKGTTTKLLYNGING 5z72 A 2.40 BS01 FLC A 1 A98 S99 I100 W128 S129 R147 F187 S189 S191 R260 A8 S9 I10 W38 S39 R57 F97 S99 S101 R168 A7Z428 GTLKLAVASIIGQHWLPKVLKTYVERYPNAKVSLITGWSSEMLKSLYEDQVHIGIIRGNPEWKGRKDYLMTDHLYLVDTEISCIDDIAHTDRPFIQFKSDSTYFQEIQHWWHQKFKTSPKQTILVDQIETCKQMALHGIGYAILPSVTLEEEDNKMPLLDTKDHPIGRDTWLLGYEPAFELKQVQAFVSVIKDMLKQ 5z72 D 2.40 BS01 FLC D 1 S99 I100 G127 W128 S129 R147 F187 S189 S191 I218 R260 S7 I8 G35 W36 S37 R55 F95 S97 S99 I126 R166 A7Z428 LKLAVASIIGQHWLPKVLKTYVERYPNAKVSLITGWSSEMLKSLYEDQVHIGIIRGNPEWKGRKDYLMTDHLYLVDTEISCIDDIAHTDRPFIQFKSDSTYFQEIQHWWHQKFKTSPKQTILVDQIETCKQMALHGIGYAILPSVTLEEKVNKMPLLDTKDHPIGRDTWLLGYEPAFELKQVQAFVSVIKDML 5z72 E 2.40 BS01 FLC E 1 A98 S99 I100 W128 S129 R147 F187 S189 D190 S191 I218 A8 S9 I10 W38 S39 R57 F92 S94 D95 S96 I112 A7Z428 GTLKLAVASIIGQHWLPKVLKTYVERYPNAKVSLITGWSSEMLKSLYEDQVHIGIIRGNPEWKGRKDYLMTDHLYLVDTEISCIDDIPFIQFKSDSTYFHWKTSPTILVDQIETCKQMALHGIGYAILPSVTLEENKMPLLDTKDHPIGRDTWLLGYEPAFELKQVQAFVSVIKDMLKQ 5z7h A 2.50 BS01 FLC A 1 S98 S99 L100 S128 T129 E130 R145 Q212 V213 R256 S11 S12 L13 S41 T42 E43 R58 Q119 V120 R163 A0A0D1IHL7 EVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQP 5z7h B 2.50 BS01 FLC B 1 S98 T129 R145 Q183 A184 D211 Q212 V213 R256 S11 T42 R58 Q94 A95 D121 Q122 V123 R166 A0A0D1IHL7 EVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKRDDVTKLPFIEFQADPIYINQIKQWYNDNLQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQP 5z7h C 2.50 BS01 FLC C 1 S98 S99 L100 S128 T129 R145 Q183 A184 D211 Q212 V213 R256 S11 S12 L13 S41 T42 R58 Q90 A91 D118 Q119 V120 R163 A0A0D1IHL7 EVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQP 5z7h D 2.50 BS01 FLC D 1 S98 L100 S128 T129 R145 Q183 A184 V213 R256 S11 L13 S41 T42 R58 Q94 A95 V124 R167 A0A0D1IHL7 EVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKRDDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQP 5z7h F 2.50 BS01 FLC F 1 S98 S99 L100 S128 T129 E130 R145 A184 D211 Q212 V213 R256 S11 S12 L13 S41 T42 E43 R58 A92 D119 Q120 V121 R164 A0A0D1IHL7 EVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQP 6aox A 2.10 BS01 TF0 A 1 F1 N44 D45 Y46 D51 D53 K132 A134 G139 N140 R142 F1 N44 D45 Y46 D51 D53 K124 A126 G131 N132 R134 Q1RBS0 FSCNVDGGSSIGAGTTSVYVNLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNNVTYPFPLTTNTNVLDIGDKTPMPLPLKLYITVIKAGEVIARIHMYKIATLGSGNPRNFTWNIISNNSV 6aoy B 1.80 BS01 145 B 1 F1 N44 D45 D51 D53 K132 A134 N140 F1 N44 D45 D51 D53 K132 A134 N140 Q1RBS0 FSCNVDGGSSIGAGTTSVYVNLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNNVTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPVGAAGGVVIKAGEVIARIHMYKIATLGSGNPRNFTWNIISNNSVVMP 6arm A 1.50 BS01 145 A 1 F1 N44 D45 Y46 D51 D53 K132 A134 N140 F1 N44 D45 Y46 D51 D53 K127 A129 N135 Q1RBS0 FSCNVDGGSSIGAGTTSVYVNLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNNVTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPGVVIKAGEVIARIHMYKIATLGSGNPRNFTWNIISNNSVVM 6arn B 1.25 BS01 BQY B 1 F1 S2 N44 D45 Y46 D51 D53 K132 A134 N140 F1 S2 N44 D45 Y46 D51 D53 K128 A130 N136 Q1RBS0 FSCNVDGGSSIGAGTTSVYVNLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNNVTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPVGVVIKAGEVIARIHMYKIATLGSGNPRNFTWNIISNNSVVM 6as8 A 2.10 BS01 BTG A 1 F1 S2 G12 N44 D45 Y46 D51 D53 K132 A134 G139 N140 R142 F1 S2 G12 N44 D45 Y46 D51 D53 K128 A130 G135 N136 R138 Q1RBS0 FSCNVDGGSSIGAGTTSVYVNLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNNVTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPVGVVIKAGEVIARIHMYKIATLGSGNPRNFTWNIISNNSVVMP 6at5 A 1.50 BS01 III C 1 Y7 Y9 N63 I66 Y67 T73 S77 N80 Y84 L95 Y99 D114 Y116 Y123 T143 W147 A150 E152 Q155 R156 Y159 W167 Y171 Y7 Y9 N63 I66 Y67 T73 S77 N80 Y84 L95 Y99 D114 Y116 Y123 T143 W147 A150 E152 Q155 R156 Y159 W167 Y171 P01889 GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWE 6auc A 1.46 BS01 OLS A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 A86 S88 T90 W92 W108 L110 S112 A121 S122 L124 D128 N12 L14 S16 Y32 S34 V36 G37 N38 W68 A75 S77 T79 W81 W97 L99 S101 A110 S111 L113 D117 P22629 29401385 RDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAQARINTQWLLTSGTTEANAWASTLVGHDTFTKV 6aue A 1.36 BS01 OL3 A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 A86 S88 T90 W92 W108 L110 Y112 T114 A121 S122 D128 N11 L13 S15 Y31 S33 V35 G36 N37 W67 A74 S76 T78 W80 W96 L98 Y100 T102 A109 S110 D116 P22629 29401385 DEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAQARINTQWLLTYGTTEANAWASTLVGHDTFTKV 6auh A 1.60 BS01 OL5 A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 S88 T90 W92 W108 L110 Y112 A121 S122 D128 N12 L14 S16 Y32 S34 V36 G37 N38 W68 S77 T79 W81 W97 L99 Y101 A110 S111 D117 P22629 29401385 RDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAQARINTQWLLTYGTTEANAWASTLVGHDTFTKVK 6aul A 1.36 BS01 BTN A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 A86 S88 T90 W92 W108 Y112 D128 N13 L15 S17 Y33 S35 V37 G38 N39 W69 A76 S78 T80 W82 W98 Y102 D118 P22629 29401385 GRDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAQARINTQWLLTYGTTEANAWASTLVGHDTFTKV 6auo A 1.70 BS01 OL4 A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 S88 T90 W92 W108 L110 F112 D128 N12 L14 S16 Y32 S34 V36 G37 N38 W68 S77 T79 W81 W97 L99 F101 D117 P22629 29401385 RDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAQARINTQWLLTFGTTEANAWASTLVGHDTFTKV 6avf A 2.03 BS01 III P 1 Y34 Q51 E94 I95 L96 Y32 Q49 E92 I93 L94 A0A0B4J268 LAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGEILDNFNKFYFGSGTKLNVKPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 6avf B 2.03 BS01 III P 1 R96 Q97 D100 R95 Q96 D99 A0A5B6 VKVTQSSRYLVKRTGEKVFLECVQDMDHENMFWYRQDPGLGLRLIYFSYDVKMKEKGDIPEGYSVSREKKERFSLILESASTNQTSMYLCASSQRQEGDTQYFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 6avf H 2.03 BS01 III P 1 Y7 Y9 R62 N63 I66 Y67 Q70 T73 S77 N80 Y84 Y99 D114 Y116 Y123 T143 K146 W147 E152 Q155 R156 Y159 W167 Y171 Y7 Y9 R62 N63 I66 Y67 Q70 T73 S77 N80 Y84 Y99 D114 Y116 Y123 T143 K146 W147 E152 Q155 R156 Y159 W167 Y171 P01889 GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWE 6avg C 2.60 BS01 III P 1 Y35 Q52 V94 D95 Y31 Q48 V90 D91 A0A0B4J268 AKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVVDQKLVFGTGTRLLVSPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 6avg D 2.60 BS01 III P 1 S34 Y36 S97 G98 S103 N104 E105 Q106 S32 Y34 S95 G96 S101 N102 E103 Q104 A0A0B4J1U6 MDSGVTQTPKHLITATGQRVTLRCSPRSGDLSVYWYQQSLDQGLQFLIQYYNGEERAKGNILERFSAQQFPDLHSELNLSSLELGDSALYFCASSGGHTGSNEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 6avg G 2.60 BS01 III P 1 Y7 Y9 R62 N63 I66 Y67 T73 S77 N80 L81 Y84 Y99 Y116 Y123 T143 K146 W147 E152 Q155 R156 Y159 E163 W167 Y171 Y7 Y9 R62 N63 I66 Y67 T73 S77 N80 L81 Y84 Y99 Y116 Y123 T143 K146 W147 E152 Q155 R156 Y159 E163 W167 Y171 P01889 GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 6avg B 2.60 BS01 III Q 1 Y35 Q52 V94 Y31 Q48 V90 A0A0B4J268 AKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVVDQKLVFGTGTRLLVSPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 6avs A 2.02 BS02 NMM A 1 E238 Y243 Y272 Q275 W310 S318 H321 D323 E58 Y63 Y92 Q95 W130 S138 H141 D143 1.14.11.27 Q8N371 GGTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS 6ax3 A 2.25 BS01 2MR A 1 E238 Q275 W310 I317 S318 H321 D323 W414 E58 Q95 W130 I137 S138 H141 D143 W234 1.14.11.27 Q8N371 GSGVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS 6b2u A 2.04 BS02 CER A 1 A142 C143 L253 L254 G257 V287 N315 I345 G346 S347 A129 C130 L226 L227 G230 V260 N288 I318 G319 S320 Q8PDX2 LVPRGSHMLFQNVSIAGLAHIDAPHTLTSKEINERLQPTYDRLGIKTDVLGDVAGIHARRLWDQDVQASDAATQAARKALIDANIGIEKIGLLINTSVSRDYLEPSTASIVSGNLGVSDHCMTFDVANACLAFINGMDIAARMLERGEIDYALVVDGETANLVYEKTLERMTSPDVTEEEFRNELAALTLGCGAAAMVMARSELVPDAPRYKGGVTRSATEWNRLLLIEGIKLAQKTFVAAKQVLGWAVEELDQFVINQVSRPHTAAFVKSFGIDPAKVMTIFGEHGNIGPASVPIVLSKLKELGRLKKGDRIALLGIGSGLNCSMAEVVW 6b5q A 2.16 BS01 CZS D 1 I86 P97 V102 A106 A111 T113 Q114 C115 E116 F117 F164 I25 P36 V41 A45 A50 T52 Q53 C54 E55 F56 F103 Q96GG9 29438612 RKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQI 6b5q A 2.16 BS02 2KY D 1 A98 Q114 M177 A180 Y181 A37 Q53 M116 A119 Y120 Q96GG9 29438612 RKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQI 6b5q A 2.16 BS03 MLY D 1 T113 Q114 C115 A165 K166 N167 M177 T52 Q53 C54 A104 K105 N106 M116 Q96GG9 29438612 RKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQI 6b5q A 2.16 BS04 1XY D 1 I83 I86 Q87 P97 C115 I22 I25 Q26 P36 C54 Q96GG9 29438612 RKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQI 6b5q B 2.16 BS02 2KY E 1 Q114 M177 A180 Y181 Q49 M112 A115 Y116 Q96GG9 29438612 RKKLEQLYNRYKDPKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQI 6b5q B 2.16 BS03 MLY E 1 T113 Q114 C115 A165 K166 N167 P168 M177 T48 Q49 C50 A100 K101 N102 P103 M112 Q96GG9 29438612 RKKLEQLYNRYKDPKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQI 6bbz A 1.90 BS01 SIS A 1 S79 Y85 E86 Y113 F116 D136 Y159 D183 H189 S225 N226 D239 S61 Y67 E68 Y95 F98 D118 Y141 D165 H171 S207 N208 D221 Q47030 TPWSKSELVRQLRDLGVRSGDMVMPHVSLRAVGPLADGPQTLVDALIEAVGPTGNILAFVSWRDSPYEQTLGHDAPPAAIAQSWPAFDPDHAPAYPGFGAINEFIRTYPGCRRTAHPDASMAAIGPDAAWLVAPHEMGAAYGPRSPIARFLAHAGKILSIGAGPDAVTALHYAEAVARIEGKRRVTYSMPLLREGKRVWVTTSDWDSNGILDEYAAPDGPDAVERIARDYLARTRVAQGPVGGAQSRLIDAADIVSFGIEWLEARHA 6bbz A 1.90 BS02 MG A 1 N73 D145 N55 D127 Q47030 TPWSKSELVRQLRDLGVRSGDMVMPHVSLRAVGPLADGPQTLVDALIEAVGPTGNILAFVSWRDSPYEQTLGHDAPPAAIAQSWPAFDPDHAPAYPGFGAINEFIRTYPGCRRTAHPDASMAAIGPDAAWLVAPHEMGAAYGPRSPIARFLAHAGKILSIGAGPDAVTALHYAEAVARIEGKRRVTYSMPLLREGKRVWVTTSDWDSNGILDEYAAPDGPDAVERIARDYLARTRVAQGPVGGAQSRLIDAADIVSFGIEWLEARHA 6bc2 A 2.20 BS01 DVM A 1 S79 Y85 Y113 F116 D136 Y159 H189 S225 N226 D239 S61 Y67 Y95 F98 D118 Y141 H171 S207 N208 D221 Q47030 TPWSKSELVRQLRDLGVRSGDMVMPHVSLRAVGPLADGPQTLVDALIEAVGPTGNILAFVSWRDSPYEQTLGHDAPPAAIAQSWPAFDPDHAPAYPGFGAINEFIRTYPGCRRTAHPDASMAAIGPDAAWLVAPHEMGAAYGPRSPIARFLAHAGKILSIGAGPDAVTALHYAEAVARIEGKRRVTYSMPLLREGKRVWVTTSDWDSNGILDEYAAPDGPDAVERIARDYLARTRVAQGPVGGAQSRLIDAADIVSFGIEWLEARHAA 6bc3 A 2.05 BS01 COA A 1 H44 V45 S46 L47 R48 P57 F77 F116 G117 A118 F122 A180 D183 A184 T186 H26 V27 S28 L29 R30 P39 F59 F98 G99 A100 F104 A162 D165 A166 T168 Q47030 TPWSKSELVRQLRDLGVRSGDMVMPHVSLRAVGPLADGPQTLVDALIEAVGPTGNILAFVSWRDSPYEQTLGHDAPPAAIAQSWPAFDPDHAPAYPGFGAINEFIRTYPGCRRTAHPDASMAAIGPDAAWLVAPHEMGAAYGPRSPIARFLAHAGKILSIGAGPDAVTALHYAEAVARIEGKRRVTYSMPLLREGKRVWVTTSDWDSNGILDEYAAPDGPDAVERIARDYLARTRVAQGPVGGAQSRLIDAADIVSFGIEWLEARHAA 6bc4 A 2.05 BS01 ACO A 1 H44 V45 S46 L47 R48 P57 F77 F116 G117 A118 F122 A180 D183 A184 V185 T186 H189 V241 H26 V27 S28 L29 R30 P39 F59 F98 G99 A100 F104 A162 D165 A166 V167 T168 H171 V223 Q47030 TPWSKSELVRQLRDLGVRSGDMVMPHVSLRAVGPLADGPQTLVDALIEAVGPTGNILAFVSWRDSPYEQTLGHDAPPAAIAQSWPAFDPDHAPAYPGFGAINEFIRTYPGCRRTAHPDASMAAIGPDAAWLVAPHEMGAAYGPRSPIARFLAHAGKILSIGAGPDAVTALHYAEAVARIEGKRRVTYSMPLLREGKRVWVTTSDWDSNGILDEYAAPDGPDAVERIARDYLARTRVAQGPVGGAQSRLIDAADIVSFGIEWLEARHAA 6bc5 A 2.20 BS01 COA A 1 H44 V45 S46 L47 R48 P57 F77 F116 G117 A118 F122 A184 T186 H189 H26 V27 S28 L29 R30 P39 F59 F98 G99 A100 F104 A166 T168 H171 Q47030 TPWSKSELVRQLRDLGVRSGDMVMPHVSLRAVGPLADGPQTLVDALIEAVGPTGNILAFVSWRDSPYEQTLGHDAPPAAIAQSWPAFDPDHAPAYPGFGAINEFIRTYPGCRRTAHPDASMAAIGPDAAWLVAPHEMGAAYGPRSPIARFLAHAGKILSIGAGPDAVTALHYAEAVARIEGKRRVTYSMPLLREGKRVWVTTSDWDSNGILDEYAAPDGPDAVERIARDYLARTRVAQGPVGGAQSRLIDAADIVSFGIEWLEARHAA 6bhv A 2.30 BS01 DQV A 1 H862 G863 S864 N868 G871 I872 Q875 G876 L877 R878 A880 Y889 M890 Y896 F897 S904 Y907 E988 H90 G91 S92 N96 G99 I100 Q103 G104 L105 R106 A108 Y117 M118 Y124 F125 S132 Y135 E216 2.4.2.30 P09874 SKLPKPVQDLIKMIFGPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 6bhv B 2.30 BS01 DQV B 1 H862 G863 S864 N868 G871 I872 Q875 G876 L877 R878 Y889 M890 G894 Y896 F897 K903 S904 Y907 E988 H89 G90 S91 N95 G98 I99 Q102 G103 L104 R105 Y116 M117 G121 Y123 F124 K130 S131 Y134 E215 2.4.2.30 P09874 SKLPKPVQDLIKMIFPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 6bjy A 3.46 BS01 NUC R 1 R143 M149 E151 K154 K155 Y215 I218 V219 D224 C225 A226 I279 K286 S290 S291 V292 R312 N315 R317 R408 R142 M148 E150 K153 K154 Y214 I217 V218 D223 C224 A225 I278 K285 S289 S290 V291 R311 N314 R316 R407 P03521 29437970 SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPDDSTGGLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK 6bjy A 3.46 BS02 DV4 R 1 Q318 D320 K410 Q317 D319 K409 P03521 29437970 SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPDDSTGGLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK 6bjy B 3.46 BS01 NUC R 1 D23 R143 M149 E151 K155 Y215 I218 V219 D224 A226 I279 K286 S287 S290 S291 V292 R312 N315 R317 R408 D22 R142 M148 E150 K154 Y214 I217 V218 D223 A225 I278 K285 S286 S289 S290 V291 R311 N314 R316 R401 P03521 29437970 SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPDTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK 6bjy B 3.46 BS02 DV4 R 1 T311 R312 T310 R311 P03521 29437970 SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPDTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK 6bjy C 3.46 BS01 NUC R 1 R143 R146 M149 E151 K155 R214 Y215 I218 D224 A226 S285 K286 S287 S290 S291 V292 R312 N315 R317 R408 R142 R145 M148 E150 K154 R213 Y214 I217 D223 A225 S284 K285 S286 S289 S290 V291 R311 N314 R316 R399 P03521 29437970 SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK 6bjy D 3.46 BS01 NUC R 1 D23 R143 R146 M149 E151 K154 K155 R214 Y215 I218 V219 D224 K286 S290 S291 V292 R312 N315 R317 R408 D22 R142 R145 M148 E150 K153 K154 R213 Y214 I217 V218 D223 K285 S289 S290 V291 R311 N314 R316 R402 P03521 29437970 SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPDLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK 6bjy E 3.46 BS01 NUC R 1 R143 R146 M149 E151 K155 I218 D224 C225 A226 I279 S285 K286 S287 S290 S291 V292 R312 N315 R317 R408 R142 R145 M148 E150 K154 I217 D223 C224 A225 I278 S284 K285 S286 S289 S290 V291 R311 N314 R316 R407 P03521 29437970 SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPDDSTGGLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK 6bkq A 2.25 BS01 SIA A 1 Y98 G135 S136 N137 W153 H183 D190 L194 L226 S228 Y90 G127 S128 N129 W145 H175 D182 L186 L218 S220 Q91MA7 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQDQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTR 6bkq C 2.25 BS01 SIA C 1 Y98 G135 S136 N137 W153 H183 D190 L194 S228 Y90 G127 S128 N129 W145 H175 D182 L186 S220 Q91MA7 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQDQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPE 6bkq E 2.25 BS01 SIA E 1 Y98 G134 G135 S136 N137 W153 H183 D190 L194 S228 Y90 G126 G127 S128 N129 W145 H175 D182 L186 S220 Q91MA7 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQDQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPE 6bkr A 1.76 BS01 SIA A 1 Y98 G134 T135 S136 S137 K145 W153 T155 H183 D190 L194 S228 Y90 G126 T127 S128 S129 K137 W145 T147 H175 D182 L186 S220 A4GYF9 PGATLCLGHHAVPNGTIVKTITNDQIEVTNATELVQSSSTGGICDSPHQILDGENCTLIDALLGDPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYASLRSLVASSGTLEFNNESFNWAGVTQNGTSSACKRRSNKSFFSRLNWLTHLKYKYPALNVTMPNNEKFDKLYIWGVHHPVTDSDQISLYAQASGRITVSTKRSQQTVIPNIGFRPRVRDISSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRSGKSSIMRSDAPIGKCNSECITPNGSIPNDKPFQNVNRITYGACPRYVKQNTLKLATGMRNVPE 6bkr A 1.76 BS02 GAL A 1 D225 I226 D217 I218 A4GYF9 PGATLCLGHHAVPNGTIVKTITNDQIEVTNATELVQSSSTGGICDSPHQILDGENCTLIDALLGDPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYASLRSLVASSGTLEFNNESFNWAGVTQNGTSSACKRRSNKSFFSRLNWLTHLKYKYPALNVTMPNNEKFDKLYIWGVHHPVTDSDQISLYAQASGRITVSTKRSQQTVIPNIGFRPRVRDISSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRSGKSSIMRSDAPIGKCNSECITPNGSIPNDKPFQNVNRITYGACPRYVKQNTLKLATGMRNVPE 6bks A 1.80 BS01 SIA A 1 Y98 G134 T135 S136 S137 K145 W153 H183 E190 L194 I226 S228 Y90 G126 T127 S128 S129 K137 W145 H175 E182 L186 I218 S220 A4GYF9 PGATLCLGHHAVPNGTIVKTITNDQIEVTNATELVQSSSTGGICDSPHQILDGENCTLIDALLGDPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYASLRSLVASSGTLEFNNESFNWAGVTQNGTSSACKRRSNKSFFSRLNWLTHLKYKYPALNVTMPNNEKFDKLYIWGVHHPVTDSEQISLYAQASGRITVSTKRSQQTVIPNIGFRPRVRDISSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRSGKSSIMRSDAPIGKCNSECITPNGSIPNDKPFQNVNRITYGACPRYVKQNTLKLATGMRNVPE 6bkt A 1.80 BS01 SIA A 1 Y98 G134 T135 S136 S137 W153 T155 L194 I226 S228 Y90 G126 T127 S128 S129 W145 T147 L186 I218 S220 A0A0Y0S9M3 PGATLCLGHHAVPNGTIVKTITNDRIEVTNATELVQNSSIGEICDSPHQILDGENCTLIDALLGDPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYASLRSLVASSGTLEFNNESFNWTGVTQNGTSSACIRRSSSSFFSRLNWLTHLNYKYPALNVTMPNNEQFDKLYIWGVHHPGTDKDQIFLYAQSSGRITVSTKRSQQAVIPNIGSRPKIRDIPSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRSGKSSIMRSDAPIGKCKSECITPNGSIPNDKPFQNVNRITYGACPRYVKHSTLKLATGMRNVPE 6bli D 2.12 BS01 III F 1 S30 F33 Y50 Y52 G53 F97 D100 D100A A100B C100C Y100D R100E R100F W100I S29 F32 Y49 Y51 G52 F99 D102 D103 A104 C105 Y106 R107 R108 W111 VQLQESGPRLVKPSETLSLTCTVSGGSTSSYFWNWIRQPPGKGLEWIGYIYGSGSADYNPSLKSRVTISIDTSKTQFSLKLTSVTAADTAVYYCARSGFCSDDACYRRGSWFDPWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 6bli E 2.12 BS01 III F 1 D30 N31 Y32 A50 Y92 D30 N31 Y32 A50 Y92 DIQMTQSPSSLSASVGDRVTITCRASQSIDNYLNWYQQKPGKAPKLLIYAASGLQSGVPSRFSGSGSGTEFTLTVSSLHPEDFATYYCQQSYSTLTWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6bli G 2.12 BS01 III I 1 S30 S31 Y50 Y52 G53 F97 S99 D100 D100A A100B C100C Y100D R100E R100F G100G W100I S29 S30 Y49 Y51 G52 F99 S101 D102 D103 A104 C105 Y106 R107 R108 G109 W111 VQLQESGPRLVKPSETLSLTCTVSGGSTSSYFWNWIRQPPGKGLEWIGYIYGSGSADYNPSLKSRVTISIDTSKTQFSLKLTSVTAADTAVYYCARSGFCSDDACYRRGSWFDPWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 6bli H 2.12 BS01 III I 1 D30 Y32 A50 Y92 T94 D30 Y32 A50 Y92 T94 DIQMTQSPSSLSASVGDRVTITCRASQSIDNYLNWYQQKPGKAPKLLIYAASGLQSGVPSRFSGSGSGTEFTLTVSSLHPEDFATYYCQQSYSTLTWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6bli J 2.12 BS01 III L 1 S30 S31 F33 Y52 G53 F97 D100 D100A A100B C100C Y100D R100E R100F G100G S29 S30 F32 Y51 G52 F99 D102 D103 A104 C105 Y106 R107 R108 G109 VQLQESGPRLVKPSETLSLTCTVSGGSTSSYFWNWIRQPPGKGLEWIGYIYGSGSADYNPSLKSRVTISIDTSKTQFSLKLTSVTAADTAVYYCARSGFCSDDACYRRGSWFDPWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 6bli K 2.12 BS01 III L 1 D30 Y32 Y49 A50 T94 D30 Y32 Y49 A50 T94 DIQMTQSPSSLSASVGDRVTITCRASQSIDNYLNWYQQKPGKAPKLLIYAASGLQSGVPSRFSGSGSGTEFTLTVSSLHPEDFATYYCQQSYSTLTWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6blo A 3.40 BS01 NUC T 1 K332 R337 R344 Q447 G835 Y836 E1403 K291 R296 R303 Q406 G794 Y795 E1329 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCGGCGNTQPTIRKDGLKLVGSWVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSIEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMID 6blo B 3.40 BS01 NUC T 1 T463 T791 R857 R942 R1122 L1128 R1129 M1133 T374 T678 R744 R819 R999 L1005 R1006 M1010 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSAISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPITAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDR 6blo B 3.40 BS02 NUC R 1 R476 A477 G478 Q776 K979 K987 H1097 R387 A388 G389 Q663 K856 K864 H974 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSAISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPITAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDR 6blp A 3.20 BS01 NUC T 1 K332 R337 R344 Q447 G835 Y836 R839 R1386 K291 R296 R303 Q406 G794 Y795 R798 R1312 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCGGCGNTQPTIRKDGLKLVGSWVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSIEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMID 6blp A 3.20 BS02 NUC R 1 R446 Q447 D485 R405 Q406 D444 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCGGCGNTQPTIRKDGLKLVGSWVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSIEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMID 6blp A 3.20 BS06 APC A 1 P448 K752 T831 P407 K711 T790 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCGGCGNTQPTIRKDGLKLVGSWVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSIEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMID 6blp B 3.20 BS01 NUC T 1 A462 T463 T791 R857 R942 R1122 L1128 R1129 M1133 A373 T374 T678 R744 R819 R999 L1005 R1006 M1010 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSAISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPITAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDR 6bm2 A 3.40 BS01 NUC T 1 K332 R337 R344 Q447 P448 A832 Y836 K291 R296 R303 Q406 P407 A791 Y795 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCGGCGNTQPTIRKDGLKLVGSWVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSIEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMID 6bm2 A 3.40 BS02 NUC R 1 K323 R446 D485 K282 R405 D444 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCGGCGNTQPTIRKDGLKLVGSWVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSIEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMID 6bm2 B 3.40 BS01 NUC T 1 S208 T463 V482 Q531 T791 R857 R942 R1122 L1128 R1129 M1133 S142 T374 V393 Q436 T678 R744 R819 R999 L1005 R1006 M1010 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSAISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPITAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDR 6bm2 B 3.40 BS02 NUC R 1 R476 A477 Q776 K987 H1097 R387 A388 Q663 K864 H974 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSAISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPITAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDR 6bm4 A 2.95 BS01 NUC T 1 S318 K332 R337 R344 Q447 P448 A832 Y836 E1403 S277 K291 R296 R303 Q406 P407 A791 Y795 E1329 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCGGCGNTQPTIRKDGLKLVGSWVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSIEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMID 6bm4 B 2.95 BS02 NUC R 1 R476 A477 Q776 K979 K987 H1097 R387 A388 Q663 K856 K864 H974 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSAISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPITAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDR 6bq3 A 1.91 BS01 DSH A 1 Q54 L70 Q75 Y84 G106 C128 D129 I130 D131 N159 D160 A161 L179 A180 P187 C188 Y251 Q31 L47 Q52 Y61 G83 C105 D106 I107 D108 N136 D137 A138 L156 A157 P164 C165 Y228 G7K2D1 29367265 KSCWYEEEIEENLRWCFALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSYADIWGWVLASDSPLDLSAEELDIRMRQRIIEENRYLDGKTFVSSSTLSKAVRNSLNNETHVYTE 6bq3 B 1.91 BS01 DSH B 1 Q54 L70 Q75 Y84 G106 C128 D129 I130 D131 N159 D160 A161 D178 L179 A180 P187 C188 L191 Q31 L47 Q52 Y61 G83 C105 D106 I107 D108 N136 D137 A138 D155 L156 A157 P164 C165 L168 G7K2D1 29367265 KSCWYEEEIEENLRWCFALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSYADIWGWVLASDSPLDLSAEELDIRMRQRIIEENRYLDGKTFVSSSTLSKAVRNSLNNETHVYTE 6bq4 A 1.89 BS01 ADN A 1 Q54 G106 C128 D129 I130 D131 D160 A161 D178 L179 P187 C188 L191 Q31 G83 C105 D106 I107 D108 D137 A138 D155 L156 P164 C165 L168 G7K2D1 29367265 KSCWYEEEIEENLRWCFALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSYADIWGWVLASDSPLDLSAEELDIRMRQRIIEENRYLDGKTFVSSSTLSKAVRNSLNNETHVYTE 6bq5 A 1.80 BS01 MTA A 1 Q54 L70 Q75 G106 C128 D129 I130 D131 V134 N159 D160 A161 D178 L179 A180 C188 L191 Q31 L47 Q52 G83 C105 D106 I107 D108 V111 N136 D137 A138 D155 L156 A157 C165 L168 G7K2D1 29367265 KSCWYEEEIEENLRWCFALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSYADIWGWVLASDSPLDLSAEELDIRMRQRIIEENRYLDGKTFVSSSTLSKAVRNSLNNETHVYTE 6bq5 B 1.80 BS01 MTA B 1 Q54 Q75 G106 C128 D129 I130 D131 N159 D160 A161 L179 A180 C188 L191 Q31 Q52 G83 C105 D106 I107 D108 N136 D137 A138 L156 A157 C165 L168 G7K2D1 29367265 KSCWYEEEIEENLRWCFALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSYADIWGWVLASDSPLDLSAEELDIRMRQRIIEENRYLDGKTFVSSSTLSKAVRNSLNNETHVYTE 6bq6 A 1.65 BS01 TER A 1 L74 Y84 G107 D178 L179 Q214 Y251 W255 L51 Y61 G84 D155 L156 Q191 Y228 W232 G7K2D1 29367265 KSCWYEEEIEENLRWCFALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSYADIWGWVLASDSPLDLSAEELDIRMRQRIIEENRYLDGKTFVSSSTLSKAVRNSLNNETHVYT 6bq6 B 1.65 BS01 TER B 1 E30 L74 Q75 Y84 G107 D178 L179 Y251 W255 E7 L51 Q52 Y61 G84 D155 L156 Y228 W232 G7K2D1 29367265 KSCWYEEEIEENLRWCFALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSYADIWGWVLASDSPLDLSAEELDIRMRQRIIEENRYLDGKTFVSSSTLSKAVRNSLNNETHVYTE 6bq7 A 1.95 BS01 SPD A 1 E30 L74 Q75 D178 L179 Y251 W255 E7 L51 Q52 D155 L156 Y228 W232 G7K2D1 29367265 KSCWYEEEIEENLRWCFALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSYADIWGWVLASDSPLDLSAEELDIRMRQRIIEENRYLDGKTFVSSSTLSKAVRNSLNNETHVYTE 6bq7 B 1.95 BS01 SPD B 1 E30 L74 Q75 Y84 D178 Y251 W255 E7 L51 Q52 Y61 D155 Y228 W232 G7K2D1 29367265 KSCWYEEEIEENLRWCFALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMPKNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSRLEVVINDAKAELEGKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPKLKKGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHIPSYADIWGWVLASDSPLDLSAEELDIRMRQRIIEENRYLDGKTFVSSSTLSKAVRNSLNNETHVYT 6bqf A 3.35 BS01 NUC T 1 K330 K332 R337 R344 Q447 Y836 E1403 K289 K291 R296 R303 Q406 Y795 E1329 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCGGCGNTQPTIRKDGLKLVGSWVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSIEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMID 6bqf B 3.35 BS01 NUC T 1 S208 T463 V482 T791 R857 R942 R1122 R1129 M1133 S142 T374 V393 T678 R744 R819 R999 R1006 M1010 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSAISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPITAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDR 6bqf B 3.35 BS02 NUC R 1 R476 A477 Q481 Q776 K987 H1097 R387 A388 Q392 Q663 K864 H974 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSAISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPITAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDR 6bqw A 4.20 BS01 ANP A 1 G10 N11 F12 S13 K15 E151 G170 S171 G226 Y255 N258 G10 N11 F12 S13 K15 E151 G170 S171 G226 Y255 N258 O52947 29440491 MTLTTVIDIGNFSTKYAYKDKKQIKVGSFPSILHSYKPLEDYEGMERVEYNGLDYYVGETVKNFYFGREEQMYFGNTRKGHMEGQIRLVYALYTIFKETGKKEFNLILTCPYESMVTDKKYFVQHFEGEREVIVEGKSFKFTVHNIVMAAEGLGALNFSDSLNCVIVDAGSKTLNVLYLINGSISKMDSHTINGGTIDNSIMDLAKTFAKTCSNIDYDYPIVCTGGKAEEMKECLENVGYSTVSSAELGEDKPSYYVNSVGLLLKYGRKFEEMFA 6bsx A 1.65 BS02 E7S A 1 A10 E40 T61 A62 G63 Q64 Y74 Y81 A9 E39 T60 A61 G62 Q63 Y73 Y80 Q15382 29416044 PQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKLE 6bsx B 1.65 BS01 GDP B 1 R15 S16 V17 G18 K19 S20 S21 F31 D33 N119 K120 D122 L123 S149 A150 R14 S15 V16 G17 K18 S19 S20 F30 D32 N118 K119 D121 L122 S148 A149 Q15382 29416044 PQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKLE 6bsx B 1.65 BS02 E7S B 1 A10 E40 T61 G63 Q64 Y74 Y81 A9 E39 T60 G62 Q63 Y73 Y80 Q15382 29416044 PQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKLE 6bsx C 1.65 BS02 E7S C 1 A10 E40 T61 A62 G63 Q64 F70 Y74 A9 E39 T60 A61 G62 Q63 F69 Y73 Q15382 29416044 PQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKLE 6bt0 B 2.60 BS01 MG B 1 S20 D36 D60 S18 D34 D58 Q15382 29416044 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKL 6bt0 B 2.60 BS02 GDP B 1 S16 G18 K19 S20 S21 F31 D33 N119 K120 D122 L123 S149 A150 K151 S14 G16 K17 S18 S19 F29 D31 N117 K118 D120 L121 S147 A148 K149 Q15382 29416044 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKL 6bt0 B 2.60 BS03 E7V B 1 E40 A62 G63 F70 Y74 E38 A60 G61 F68 Y72 Q15382 29416044 QSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKL 6bxq B 1.58 BS01 III A 1 Y13 M51 Y65 E69 N72 M73 Y105 D120 L162 Y165 W173 Y177 Y7 M45 Y59 E63 N66 M67 Y99 D114 L156 Y159 W167 Y171 P18465 29437277 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 6bxq B 1.58 BS02 III A 2 A75 T79 E82 N83 I86 Y90 I101 Y129 T149 K152 W153 V158 Q161 A69 T73 E76 N77 I80 Y84 I95 Y123 T143 K146 W147 V152 Q155 P18465 29437277 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 6bz2 A 1.67 BS01 7OA B 1 R8 D25 G27 A28 D29 D30 V32 G48 G49 P81 V82 I84 R8 D25 G27 A28 D29 D30 V32 G48 G49 P81 V82 I84 Q5RZ08 29437300 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF 6c2w A 4.12 BS06 MG A 6 E14 R15 E19 E14 R15 E19 3.4.21.5 P00734 29440720 ANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINCTTHPGADLQENFCRNPDSSTMGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTCNVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGEYLE 6c86 A 2.15 BS01 KAA A 1 G249 A250 A271 E273 R295 E297 T302 H303 N304 F307 E311 Y313 E464 L465 N467 Y469 E471 G516 W517 G518 G520 R523 I534 G205 A206 A227 E229 R251 E253 T258 H259 N260 F263 E267 Y269 E420 L421 N423 Y425 E427 G472 W473 G474 G476 R479 I490 6.1.1.6 Q5CR27 SHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 6c9z A 2.10 BS01 VOG A 1 D73 Y169 D197 I198 W271 W305 D307 M308 R404 W417 D420 F453 H478 D74 Y170 D198 I199 W272 W306 D308 M309 R405 W418 D421 F454 H479 3.2.1.- A5ZY13 AMIRKYRYGAPFDTEALTEKIETAEEAFPYGEISQKEGFAFTYIMDEDDIVYGLGESNRGINKRGYCYISNCTDDPIHTEDKRSLYGAHNFIIVSGKTTFGLFFDYPSKLTFDIGYTRMDTLKVSCENADLDIYVIEGENAYDIVKQFRRVIGRSYIPPKFAFGFGQSRYGYTTKEDFRAVAKGYRENHIPIDMIYMDIDYMQDFKDFTVNEKNFPDFPEFVKEMKDQELRLIPIIDAGVKVEKGYEVYEEGVKNNYFCKREDGSDFVAAVWPGDTHFPDMLNPEARKWFGDKYRFLIDQGIEGFWNDMNEPAIFYSSEGLAEAKEFAGEFAKDTEGKIHPWAMQAKMKDIVNSPEDYKRFYHNVNGKKIRHDKVHNLFGYNMTRAAGEAFERIDPEKRFLMFSRSSYIGMHRYGGIWMGDNKSWWSHILLNLKMLPSLNMCGFMYTGADLGGFGDDTTRDLLLRFLALGVFTPLMRDHAAEGTREQECYQFENIEDFRSVINARYRLVPYLYSEYMKAALNDDMYFKPLGFVYPDDKMAIRVEDQLMLGNEIMIAPVYEQNARGRYVYLPEEMKFIKFMPDGSISEEVLEKGVHYVDVALNEVPLFIRSGKCIPVAEAAECVKDIDTENMQLIGYEGSSYTLYEDDGIHKDYDKKENYRVLTK 6ca0 C 5.75 BS01 NUC G 1 W183 D199 R371 E374 W181 D197 R369 E372 2.7.7.6 P0A8V2 YSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 6ca0 D 5.75 BS01 NUC I 1 L120 R1148 L107 R1124 2.7.7.6 P0A8T7 TEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 6ca0 D 5.75 BS02 NUC J 1 R311 K332 K334 Q335 Y795 E1327 R298 K319 K321 Q322 Y782 E1303 2.7.7.6 P0A8T7 TEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 6ca0 D 5.75 BS03 MG D 1 D460 F461 D462 D464 D447 F448 D449 D451 2.7.7.6 P0A8T7 TEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 6ca0 D 5.75 BS04 ZN D 1 C70 L71 C72 C88 C57 L58 C59 C75 2.7.7.6 P0A8T7 TEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 6ca0 D 5.75 BS05 ZN D 2 C814 T816 C888 D889 C898 C801 T803 C875 D876 C885 2.7.7.6 P0A8T7 TEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 6ca0 F 5.75 BS01 NUC G 1 V98 R99 M102 R103 G106 L110 L111 A382 N383 R385 L386 S389 K392 F401 K418 F419 E420 R423 Y425 K426 S428 T429 Y430 T432 W433 W434 Q437 R441 R451 P453 H455 E585 R586 Q589 K593 V9 R10 M13 R14 G17 L21 L22 A242 N243 R245 L246 S249 K252 F261 K278 F279 E280 R283 Y285 K286 S288 T289 Y290 T292 W293 W294 Q297 R301 R311 P313 H315 E445 R446 Q449 K453 P00579 EIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSDLITGFVDDPELAREKFAELRAQYVVTRDTIKATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLD 6ca0 F 5.75 BS02 NUC H 1 R157 Y394 R397 Q437 I439 T440 I443 E458 R562 T572 L573 E574 E585 R588 R68 Y254 R257 Q297 I299 T300 I303 E318 R422 T432 L433 E434 E445 R448 P00579 EIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSDLITGFVDDPELAREKFAELRAQYVVTRDTIKATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLD 6ca1 A 1.95 BS01 MIG A 1 W169 D197 I198 W271 W305 D307 M308 R404 W417 D420 F453 H478 W170 D198 I199 W272 W306 D308 M309 R405 W418 D421 F454 H479 3.2.1.- A5ZY13 AMIRKYRYGAPFDTEALTEKIETAEEAFPYGEISQKEGFAFTYIMDEDDIVYGLGESNRGINKRGYCYISNCTDDPIHTEDKRSLYGAHNFIIVSGKTTFGLFFDYPSKLTFDIGYTRMDTLKVSCENADLDIYVIEGENAYDIVKQFRRVIGRSYIPPKFAFGFGQSRWGYTTKEDFRAVAKGYRENHIPIDMIYMDIDYMQDFKDFTVNEKNFPDFPEFVKEMKDQELRLIPIIDAGVKVEKGYEVYEEGVKNNYFCKREDGSDFVAAVWPGDTHFPDMLNPEARKWFGDKYRFLIDQGIEGFWNDMNEPAIFYSSEGLAEAKEFAGEFAKDTEGKIHPWAMQAKMKDIVNSPEDYKRFYHNVNGKKIRHDKVHNLFGYNMTRAAGEAFERIDPEKRFLMFSRSSYIGMHRYGGIWMGDNKSWWSHILLNLKMLPSLNMCGFMYTGADLGGFGDDTTRDLLLRFLALGVFTPLMRDHAAEGTREQECYQFENIEDFRSVINARYRLVPYLYSEYMKAALNDDMYFKPLGFVYPDDKMAIRVEDQLMLGNEIMIAPVYEQNARGRYVYLPEEMKFIKFMPDGSISEEVLEKGVHYVDVALNEVPLFIRSGKCIPVAEAAECVKDIDTENMQLIGYEGSSYTLYEDDGIHKDYDKKENYRVLTK 6ca3 B 1.74 BS01 MIG B 1 Y169 D197 W271 W305 D307 M308 R404 W417 D420 F453 H478 Y171 D199 W273 W307 D309 M310 R406 W419 D422 F455 H480 3.2.1.- A5ZY13 NAMIRKYRYGAPFDTEALTEKIETAEEAFPYGEISQKEGFAFTYIMDEDDIVYGLGESNRGINKRGYCYISNCTDDPIHTEDKRSLYGAHNFIIVSGKTTFGLFFDYPSKLTFDIGYTRMDTLKVSCENADLDIYVIEGENAYDIVKQFRRVIGRSYIPPKFAFGFGQSRYGYTTKEDFRAVAKGYRENHIPIDMIYMDIDYMQDFKDFTVNEKNFPDFPEFVKEMKDQELRLIPIIDAGVKVEKGYEVYEEGVKNNYFCKREDGSDFVAAVWPGDTHFPDMLNPEARKWFGDKYRFLIDQGIEGFWNDMNEPAIFYSSEGLAEAKEFAGEFAKDTEGKIHPWAMQAKMKDIVNSPEDYKRFYHNVNGKKIRHDKVHNLFGYNMTRAAGEAFERIDPEKRFLMFSRSSYIGMHRYGGIWMGDNKSWWSHILLNLKMLPSLNMCGFMYTGADLGGFGDDTTRDLLLRFLALGVFTPLMRDHAAEGTREQECYQFENIEDFRSVINARYRLVPYLYSEYMKAALNDDMYFKPLGFVYPDDKMAIRVEDQLMLGNEIMIAPVYEQNARGRYVYLPEEMKFIKFMPDGSISEEVLEKGVHYVDVALNEVPLFIRSGKCIPVAEAAECVKDIDTENMQLIGYEGSSYTLYEDDGIHKDYDKKENYRVLTK 6caw B 1.95 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 F416 W420 G69 L70 I72 R73 W76 V204 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 T353 F381 W385 1.11.1.21 Q3JNW6 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWFPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 6cay A 2.00 BS01 ERG A 1 Y908 K910 P918 T944 N946 F955 I991 G994 T995 G998 V999 T1002 Y58 K60 P68 T94 N96 F105 I141 G144 T145 G148 V149 T152 A0A250W8A7 NDHLVIEANINAPLGKVVNLLYGEDVSYYERILKAQKNFEISPIPNNFLTKKIRDYAYTKPLSGSIGPSKTKCLITDTLEHYDLEDYVKVLSITKNPDVPSGNIFSVKTVFLFSWDKNNSTKLTVYNSVDWTGKSWIKSMIEKGTFDGVADTTKIMISEIKKILS 6cay B 2.00 BS01 ERG B 1 Y908 K910 P918 T944 N946 F955 F961 M990 I991 G994 T995 G998 V999 T1002 Y57 K59 P67 T93 N95 F104 F110 M139 I140 G143 T144 G147 V148 T151 A0A250W8A7 DHLVIEANINAPLGKVVNLLYGEDVSYYERILKAQKNFEISPIPNNFLTKKIRDYAYTKPLSGSIGPSKTKCLITDTLEHYDLEDYVKVLSITKNPDVPSGNIFSVKTVFLFSWDKNNSTKLTVYNSVDWTGKSWIKSMIEKGTFDGVADTTKIMISEIKKILSD 6cb4 A 1.30 BS01 BEZ A 1 N284 L286 F294 H297 N299 L306 I348 R376 N221 L223 F231 H234 N236 L243 I285 R313 P50477 NNPYLFRSNKFLTLFKNQHGSLRLLQRFNEDTEKLENLRDYRVLEYCSKPNTLLLPHHSDSDLLVLVLEGQAILVLVNPDGRDTYKLDQGDAIKIQAGTPFYLINPDNNQNLRILKFAITFRRPGTVEDFFLSSTKRLPSYLSAFSKNFLEASYDSPYDEIEQTLLQEEQEGVIVKMPKDSQNKPFNLRSRDPIYSNNYGKLYEITPEKNSQLRDLDILLNCLQMNEGALFVPHYNSRATVILVANEGRAEVELVGLEQQQQQGLESMQLRRYAATLSEGDIIVIPSSFPVALKAASDLNMVGIGVNAENNERNFLAGHKENVIRQIPRQVSDLTFPGSGEEVEELLENQKESYFVDGQPR 6cb4 A 1.30 BS02 BEZ A 2 N260 N261 Y262 G263 K264 Q287 M288 N289 N197 N198 Y199 G200 K201 Q224 M225 N226 P50477 NNPYLFRSNKFLTLFKNQHGSLRLLQRFNEDTEKLENLRDYRVLEYCSKPNTLLLPHHSDSDLLVLVLEGQAILVLVNPDGRDTYKLDQGDAIKIQAGTPFYLINPDNNQNLRILKFAITFRRPGTVEDFFLSSTKRLPSYLSAFSKNFLEASYDSPYDEIEQTLLQEEQEGVIVKMPKDSQNKPFNLRSRDPIYSNNYGKLYEITPEKNSQLRDLDILLNCLQMNEGALFVPHYNSRATVILVANEGRAEVELVGLEQQQQQGLESMQLRRYAATLSEGDIIVIPSSFPVALKAASDLNMVGIGVNAENNERNFLAGHKENVIRQIPRQVSDLTFPGSGEEVEELLENQKESYFVDGQPR 6cbq A 2.80 BS01 EVY A 1 S38 G40 F54 S56 Y58 W62 K63 Y66 I67 D75 I77 V78 G81 F101 W102 I125 M127 S35 G37 F51 S53 Y55 W59 K60 Y63 I64 D72 I74 V75 G78 F98 W99 I122 M124 Q9RMS5 29437248 EREGYLEILSRITTEEEFFSLVLEICGNYGFEFFSFGARAPFPLTAPKYHFLSNYPGEWKSRYISEDYTSIDPIVRHGLLEYTPLIWNGEDFQENRFFWEEALHHGIRHGWSIPVRGKYGLISMLSLVRSSESIAATEILEKESFLLWITSMLQATFGDLLAPRIVPESNVRLTARETEMLKWTAVGKTYGEIGLILSIDQRTVKFHIVNAMRKLNSSNKAEATMKAYAIGLLN 6cbq B 2.80 BS01 EVY B 1 S38 G40 R42 Y52 F54 S56 Y58 W62 Y66 I77 V78 G81 L82 W90 W102 I110 I125 M127 S129 S35 G37 R39 Y49 F51 S53 Y55 W59 Y63 I74 V75 G78 L79 W87 W99 I107 I122 M124 S126 Q9RMS5 29437248 EREGYLEILSRITTEEEFFSLVLEICGNYGFEFFSFGARAPFPLTAPKYHFLSNYPGEWKSRYISEDYTSIDPIVRHGLLEYTPLIWNGEDFQENRFFWEEALHHGIRHGWSIPVRGKYGLISMLSLVRSSESIAATEILEKESFLLWITSMLQATFGDLLAPRIVPESNVRLTARETEMLKWTAVGKTYGEIGLILSIDQRTVKFHIVNAMRKLNSSNKAEATMKAYAIGLLN 6cbz B 1.65 BS02 EST B 1 L346 A350 E353 L387 M388 R394 F404 H524 L525 L33 A37 E40 L74 M75 R81 F91 H200 L201 P03372 AASLTADQMVSALLDAEPPILYSFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKMVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 6cc0 A 2.50 BS01 EWM A 1 S38 G40 A41 Y52 F54 Y58 W62 Y66 D75 I77 G81 L82 W90 F101 W102 I110 I125 S126 M127 S35 G37 A38 Y49 F51 Y55 W59 Y63 D72 I74 G78 L79 W87 F98 W99 I107 I122 S123 M124 Q9RMS5 29437248 EREGYLEILSRITTEEEFFSLVLEICGNYGFEFFSFGARAPFPLTAPKYHFLSNYPGEWKSRYISEDYTSIDPIVRHGLLEYTPLIWNGEDFQENRFFWEEALHHGIRHGWSIPVRGKYGLISMLSLVRSSESIAATEILEKESFLLWITSMLQATFGDLLAPRIVPESNVRLTARETEMLKWTAVGKTYGEIGLILSIDQRTVKFHIVNAMRKLNSSNKAEATMKAYAIGLLN 6cc0 B 2.50 BS01 EWM B 1 S38 G40 Y52 F54 Y58 W62 D75 I77 V78 G81 L82 F101 W102 I110 I125 M127 S34 G36 Y48 F50 Y54 W58 D71 I73 V74 G77 L78 F97 W98 I106 I121 M123 Q9RMS5 29437248 REGYLEILSRITTEEEFFSLVLEICGNYGFEFFSFGARAPFPLTAPKYHFLSNYPGEWKSRYISEDYTSIDPIVRHGLLEYTPLIWNGEDFQENRFFWEEALHHGIRHGWSIPVRGKYGLISMLSLVRSSESIAATEILEKESFLLWITSMLQATFGDLLAPRIVPESNVRLTARETEMLKWTAVGKTYGEIGLILSIDQRTVKFHIVNAMRKLNSSNKAEATMKAYAIGLLN 6cfq A 1.72 BS02 OXY A 1 R108 H112 N141 R73 H77 N106 1.11.1.21 A0A095KYK6 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPNNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 6cgi A 2.30 BS01 UDP A 1 Q51 W52 F53 H187 F190 Y224 D226 A227 Q25 W26 F27 H161 F164 Y198 D200 A201 A0A0H3NMP8 SGSANFAGVEYPLLPLDQHTPLLFQWFERNPSRFGENQIPIINTQQNPYLNNIINAAIIEKERTIGVLVDGNFSAGQKKALAKLEKQYENIKVIYNSDLDYSMYDKKLSDIYLENIAKIEAQPANVRDEYLLGEIKKSLNEVLKNNPEESLVSSHDKRLGHVRFDFYRNLFLLKGSNAFLEAGKHGCHHLQPGGGCIYLDADMLLTGKLGTLYLPDGIAVHVSRKGNSMSLENGIIAVNRSEHPALKKGLEIMHSKPYGDPYIDGVCGGLRHYFNCSIRHNYEEFCNFIEFKHEHIFMDTSSLT 6cgi B 2.30 BS01 UDP B 1 Q51 W52 F53 F190 Y224 D226 A227 Q24 W25 F26 F163 Y197 D199 A200 A0A0H3NMP8 GSANFAGVEYPLLPLDQHTPLLFQWFERNPSRFGENQIPIINTQQNPYLNNIINAAIIEKERTIGVLVDGNFSAGQKKALAKLEKQYENIKVIYNSDLDYSMYDKKLSDIYLENIAKIEAQPANVRDEYLLGEIKKSLNEVLKNNPEESLVSSHDKRLGHVRFDFYRNLFLLKGSNAFLEAGKHGCHHLQPGGGCIYLDADMLLTGKLGTLYLPDGIAVHVSRKGNSMSLENGIIAVNRSEHPALKKGLEIMHSKPYGDPYIDGVCGGLRHYFNCSIRHNYEEFCNFIEFKHEHIFMDTSSL 6cgi C 2.30 BS01 UDP C 1 Q51 W52 F53 H187 F190 R194 Y224 D226 A227 Q26 W27 F28 H162 F165 R169 Y199 D201 A202 A0A0H3NMP8 SSGSANFAGVEYPLLPLDQHTPLLFQWFERNPSRFGENQIPIINTQQNPYLNNIINAAIIEKERTIGVLVDGNFSAGQKKALAKLEKQYENIKVIYNSDLDYSMYDKKLSDIYLENIAKIEAQPANVRDEYLLGEIKKSLNEVLKNNPEESLVSSHDKRLGHVRFDFYRNLFLLKGSNAFLEAGKHGCHHLQPGGGCIYLDADMLLTGKLGTLYLPDGIAVHVSRKGNSMSLENGIIAVNRSEHPALKKGLEIMHSKPYGDPYIDGVCGGLRHYFNCSIRHNYEEFCNFIEFKHEHIFMDTSSL 6cgi D 2.30 BS01 UDP D 1 Q51 W52 F53 Y75 H187 F190 Y224 D226 A227 Q26 W27 F28 Y50 H162 F165 Y199 D201 A202 A0A0H3NMP8 SSGSANFAGVEYPLLPLDQHTPLLFQWFERNPSRFGENQIPIINTQQNPYLNNIINAAIIEKERTIGVLVDGNFSAGQKKALAKLEKQYENIKVIYNSDLDYSMYDKKLSDIYLENIAKIEAQPANVRDEYLLGEIKKSLNEVLKNNPEESLVSSHDKRLGHVRFDFYRNLFLLKGSNAFLEAGKHGCHHLQPGGGCIYLDADMLLTGKLGTLYLPDGIAVHVSRKGNSMSLENGIIAVNRSEHPALKKGLEIMHSKPYGDPYIDGVCGGLRHYFNCSIRHNYEEFCNFIEFKHEHIFMDTSSL 6ehu A 1.95 BS01 B5E A 1 L203 V204 D205 Y239 L242 E264 L265 D266 P267 F269 I272 L201 V202 D203 Y237 L240 E262 L263 D264 P265 F267 I270 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 6ehu A 1.95 BS02 B5E A 2 L45 G46 V53 N118 F121 L124 Y125 P159 H160 V162 M163 I164 I174 M221 S224 M225 L43 G44 V51 N116 F119 L122 Y123 P157 H158 V160 M161 I162 I172 M219 S222 M223 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 6ehu A 1.95 BS03 B5E A 3 Q36 D37 Y39 L41 V101 K102 D103 T108 A110 Q34 D35 Y37 L39 V99 K100 D101 T106 A108 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 6ehu B 1.95 BS01 B5E B 1 D205 E264 L265 P267 D203 E262 L263 P265 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 6ehu B 1.95 BS02 B5E B 2 L45 G46 V53 F121 L124 Y125 L128 P159 H160 V162 M163 I164 M221 S224 M225 E230 L43 G44 V51 F119 L122 Y123 L126 P157 H158 V160 M161 I162 M219 S222 M223 E228 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 6ehu B 1.95 BS03 B5E B 3 Q36 Y39 L41 I69 V101 D103 T108 A110 Q34 Y37 L39 I67 V99 D101 T106 A108 2.7.11.1 P68400 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 6eii B 1.94 BS01 B5W B 1 L45 N118 F121 L128 Y136 P159 H160 V162 M163 I164 I174 M221 L44 N117 F120 L127 Y135 P158 H159 V161 M162 I163 I173 M220 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 6eqv A 1.90 BS01 III D 1 D154 D191 N192 H194 V231 E236 S253 W254 G255 P256 E257 D258 D264 A292 G294 D306 Y308 T309 T367 S368 D46 D83 N84 H86 V123 E128 S145 W146 G147 P148 E149 D150 D156 A184 G186 D198 Y200 T201 T259 S260 3.4.21.75 P09958 29314830 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTASGSLVPR 6eqw A 1.99 BS01 III D 1 D154 D191 N192 H194 L227 V231 E236 S253 W254 G255 P256 D258 D264 G265 A292 G294 D306 Y308 T309 T367 S368 D46 D83 N84 H86 L119 V123 E128 S145 W146 G147 P148 D150 D156 G157 A184 G186 D198 Y200 T201 T259 S260 3.4.21.75 P09958 29314830 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTASGSLVPR 6eyt A 2.21 BS01 MN A 1 D228 D325 S327 D202 D299 S301 A0A0H3NMP8 29449376 SGSANFAGVEYPLLPLDQHTPLLFQWFERNPSRFGENQIPIINTQQNPYLNNIINAAIIEKERTIGVLVDGNFSAGQKKALAKLEKQYENIKVIYNSDLDYSMYDKKLSDIYLENIAKIEAQPANVRDEYLLGEIKKSLNEVLKNNPEESLVSSHDKRLGHVRFDFYRNLFLLKGSNAFLEAGKHGCHHLQPGGGCIYLDADMLLTGKLGTLYLPDGIAVHVSRKGNSMSLENGIIAVNRSEHPALKKGLEIMHSKPYGDPYIDGVCGGLRHYFNCSIRHNYEEFCNFIEFKHEHIFMDTSSLTISSWR 6eyt A 2.21 BS02 UDP A 1 Q51 W52 F53 Y75 F190 Y224 D226 A227 D228 D325 S327 S332 S333 W334 R335 Q25 W26 F27 Y49 F164 Y198 D200 A201 D202 D299 S301 S306 S307 W308 R309 A0A0H3NMP8 29449376 SGSANFAGVEYPLLPLDQHTPLLFQWFERNPSRFGENQIPIINTQQNPYLNNIINAAIIEKERTIGVLVDGNFSAGQKKALAKLEKQYENIKVIYNSDLDYSMYDKKLSDIYLENIAKIEAQPANVRDEYLLGEIKKSLNEVLKNNPEESLVSSHDKRLGHVRFDFYRNLFLLKGSNAFLEAGKHGCHHLQPGGGCIYLDADMLLTGKLGTLYLPDGIAVHVSRKGNSMSLENGIIAVNRSEHPALKKGLEIMHSKPYGDPYIDGVCGGLRHYFNCSIRHNYEEFCNFIEFKHEHIFMDTSSLTISSWR 6eyt A 2.21 BS03 NDG A 1 H187 F190 D191 R194 D226 M229 H247 E258 N259 G260 D325 W334 R335 H161 F164 D165 R168 D200 M203 H221 E232 N233 G234 D299 W308 R309 A0A0H3NMP8 29449376 SGSANFAGVEYPLLPLDQHTPLLFQWFERNPSRFGENQIPIINTQQNPYLNNIINAAIIEKERTIGVLVDGNFSAGQKKALAKLEKQYENIKVIYNSDLDYSMYDKKLSDIYLENIAKIEAQPANVRDEYLLGEIKKSLNEVLKNNPEESLVSSHDKRLGHVRFDFYRNLFLLKGSNAFLEAGKHGCHHLQPGGGCIYLDADMLLTGKLGTLYLPDGIAVHVSRKGNSMSLENGIIAVNRSEHPALKKGLEIMHSKPYGDPYIDGVCGGLRHYFNCSIRHNYEEFCNFIEFKHEHIFMDTSSLTISSWR 6f28 A 2.40 BS02 CG8 A 1 E15 F18 Y63 P90 L91 T92 R97 G142 A143 T144 M190 E191 T194 Y217 E11 F14 Y59 P86 L87 T88 R93 G138 A139 T140 M186 E187 T190 Y213 P42264 29451794 NRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCP 6f28 B 2.40 BS04 CG8 B 1 E15 Y63 P90 L91 T92 R97 G142 A143 T144 N174 M190 E191 T194 E10 Y58 P85 L86 T87 R92 G137 A138 T139 N169 M185 E186 T189 P42264 29451794 RSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGC 6f3j A 2.20 BS03 CKQ A 1 G135 L136 Y280 N282 N284 F285 F286 E287 G288 R292 H341 H377 T378 N484 Y573 E672 A673 S674 G675 G124 L125 Y263 N265 N267 F268 F269 E270 G271 R275 H315 H351 T352 N458 Y547 E646 A647 S648 G649 2.4.1.1 P00489 29453094 QISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 6f3l A 1.90 BS02 CJW A 1 L136 N282 N284 F285 F286 H341 H377 T378 A383 N484 Y573 E672 A673 S674 G675 L125 N265 N267 F268 F269 H315 H351 T352 A357 N458 Y547 E646 A647 S648 G649 2.4.1.1 P00489 29453094 QISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 6f3r A 1.90 BS02 CKZ A 1 E88 L136 Y280 N282 N284 F285 R292 H341 H377 N484 Y573 E672 A673 S674 G675 E77 L125 Y263 N265 N267 F268 R275 H315 H351 N458 Y547 E646 A647 S648 G649 2.4.1.1 P00489 29453094 QISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 6f3u A 2.20 BS03 CNK A 1 E88 L136 N282 N284 F285 H341 H377 A383 N484 Y573 E672 A673 S674 G675 E77 L125 N265 N267 F268 H315 H351 A357 N458 Y547 E646 A647 S648 G649 2.4.1.1 P00489 29453094 QISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDFNLGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 6fai d 3.40 BS01 ZN d 1 C21 C24 C39 C42 C2 C5 C20 C23 P41057 29459436 QCRVCSSHTGLIRKYGLNICRQCFREKANDIGFNKFR 6fbv C 3.50 BS01 FI8 D 1 M1051 I1052 Q1054 D1094 T1096 V1097 K1101 E1119 S1120 M1024 I1025 Q1027 D1067 T1069 V1070 K1074 E1092 S1093 2.7.7.6 P9WGY9 SNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEAQPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAI 6fbv D 3.50 BS01 ZN D 1 C891 C968 C975 C978 C889 C966 C973 C976 2.7.7.6 P9WGY7 DVNFFDELRIGLATAEDIRQWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDEEMRHNELSTLEAEMAVERKAVEDQRDGELEARAQKLEADLAELEAEGAKADARRKVRDGGEREMRQIRDRAQRELDRLEDIWSTFTKLAPKQLIVDENLYRELVDRYGEYFTGAMGAESIQKLIENFDIDAEAESLRDVIRNGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAMPRLDMVTGLYYLTTEVPGDTGEYQPASGDHPETGVYSSPAEAIMAADRGVLSVRAKIKVRLTQLRPPVEIEAELFGHSGWQPGDAWMAETTLGRVMFNELLPLGYPFVNKQMHKKVQAAIINDLAERYPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPRKKEILDHYEERADKVEKQFQRGALNHDERNEALVEIWKEATDEVGQALREHYPDDNPIITIVDSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPVKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCQTERGIVVELAERAPDGTLIRDPYIETSAYARTLGTDAVDEAGNVIVERGQDLGDPEIDALLAAGITQVKVRSVLTCATSTGVCATCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRDITGGLPRVQELFEARVPRGKAPIADVTGRVRLEDGERFYKITIVPDDGGEEVVYDKISKRQRLRVFKHEDGSERVLSDGDHVEVGQQLMEGSADPHEVLRVQGPREVQIHLVREVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLIDRAEFEAENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGINRYRNIAVQPTEEARAA 6fbv D 3.50 BS03 MG D 1 D535 D537 D539 D533 D535 D537 2.7.7.6 P9WGY7 DVNFFDELRIGLATAEDIRQWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDEEMRHNELSTLEAEMAVERKAVEDQRDGELEARAQKLEADLAELEAEGAKADARRKVRDGGEREMRQIRDRAQRELDRLEDIWSTFTKLAPKQLIVDENLYRELVDRYGEYFTGAMGAESIQKLIENFDIDAEAESLRDVIRNGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAMPRLDMVTGLYYLTTEVPGDTGEYQPASGDHPETGVYSSPAEAIMAADRGVLSVRAKIKVRLTQLRPPVEIEAELFGHSGWQPGDAWMAETTLGRVMFNELLPLGYPFVNKQMHKKVQAAIINDLAERYPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPRKKEILDHYEERADKVEKQFQRGALNHDERNEALVEIWKEATDEVGQALREHYPDDNPIITIVDSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPVKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCQTERGIVVELAERAPDGTLIRDPYIETSAYARTLGTDAVDEAGNVIVERGQDLGDPEIDALLAAGITQVKVRSVLTCATSTGVCATCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRDITGGLPRVQELFEARVPRGKAPIADVTGRVRLEDGERFYKITIVPDDGGEEVVYDKISKRQRLRVFKHEDGSERVLSDGDHVEVGQQLMEGSADPHEVLRVQGPREVQIHLVREVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLIDRAEFEAENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGINRYRNIAVQPTEEARAA 6fbv D 3.50 BS04 FI8 D 1 R84 K86 R89 E323 L324 V328 R412 Q415 R82 K84 R87 E321 L322 V326 R410 Q413 2.7.7.6 P9WGY7 DVNFFDELRIGLATAEDIRQWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDEEMRHNELSTLEAEMAVERKAVEDQRDGELEARAQKLEADLAELEAEGAKADARRKVRDGGEREMRQIRDRAQRELDRLEDIWSTFTKLAPKQLIVDENLYRELVDRYGEYFTGAMGAESIQKLIENFDIDAEAESLRDVIRNGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAMPRLDMVTGLYYLTTEVPGDTGEYQPASGDHPETGVYSSPAEAIMAADRGVLSVRAKIKVRLTQLRPPVEIEAELFGHSGWQPGDAWMAETTLGRVMFNELLPLGYPFVNKQMHKKVQAAIINDLAERYPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPRKKEILDHYEERADKVEKQFQRGALNHDERNEALVEIWKEATDEVGQALREHYPDDNPIITIVDSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPVKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCQTERGIVVELAERAPDGTLIRDPYIETSAYARTLGTDAVDEAGNVIVERGQDLGDPEIDALLAAGITQVKVRSVLTCATSTGVCATCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRDITGGLPRVQELFEARVPRGKAPIADVTGRVRLEDGERFYKITIVPDDGGEEVVYDKISKRQRLRVFKHEDGSERVLSDGDHVEVGQQLMEGSADPHEVLRVQGPREVQIHLVREVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLIDRAEFEAENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGINRYRNIAVQPTEEARAA 6fbv F 3.50 BS01 FI8 D 1 L423 D424 L199 D200 P9WGI1 ADSVRAYLKQIGKVALLNAEEEVELAKRIEAGLYATQLMTELSERGEKLPAAQRRDMMWICRDGDRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQQLGDFIEDSVAVDAVSFTLLQDQLQSVLDTLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD 6fek A 2.30 BS01 ADN A 1 L730 G731 G733 V738 A756 I788 V804 E805 Y806 A807 G810 S811 L881 L31 G32 G34 V39 A57 I89 V105 E106 Y107 A108 G111 S112 L167 2.7.10.1 P07949 29434222 GPLSLSVDAFKILAAPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDFYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMV 6fm9 A 3.60 BS01 P6L A 1 A203 S204 W243 R377 S391 A176 S177 W216 R350 S364 2.7.8.15 Q9H3H5 LPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGVISGAVFLIILFCFIPFPFLPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCPRHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNNMTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLF 6fny A 2.79 BS01 CA A 1 D14 L53 C54 D296 H297 D17 L56 C57 D299 H300 3.1.6.6 O69787 29458126 GDPVTTGKPNILIIMVDQLNGKLFPDGPADFLHAPNLKALAKRSARFHNNYTSSPLCAPARASFMAGQLPSRTRVYDNAAEYQSSIPTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEERLTTDIYPADFGWTPDYRKPGERIDWWYHNLGSVTGAGVAEITNQMEYDDEVAFLANQKLYQLSRENDDESRRPWCLTVSFTHPHDPYVARRKFWDLYEDCEHLTPEVGAIPLDEQDPHSQRIMLSCDYQNFDVTEENVRRSRRAYFANISYLDEKVGELIDTLTRTRMLDDTLILFCSDHGDMLGERGLWFKMNFFEGSARVPLMIAGPGIAPGLHLTPTSNLDVTPTLADLAGISLEEVRPWTDGVSLVPMVNGVERTEPVLMEYAAEASYAPLVAIREGKWKYVYCALDPEQLFDLEADPLELTNLAENPRGPVDQATLTAFRDMRAAHWDMEAFDAAVRESQARRWVVYEALRNGAYYPWDHQPLQKASERYMRNHMNLDTLEESKRYPRGE 6fny C 2.79 BS01 CA C 1 D14 Q15 C54 D296 H297 D15 Q16 C55 D297 H298 3.1.6.6 O69787 29458126 PVTTGKPNILIIMVDQLNGKLFPDGPADFLHAPNLKALAKRSARFHNNYTSSPLCAPARASFMAGQLPSRTRVYDNAAEYQSSIPTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEERLTTDIYPADFGWTPDYRKPGERIDWWYHNLGSVTGAGVAEITNQMEYDDEVAFLANQKLYQLSRENDDESRRPWCLTVSFTHPHDPYVARRKFWDLYEDCEHLTPEVGAIPLDEQDPHSQRIMLSCDYQNFDVTEENVRRSRRAYFANISYLDEKVGELIDTLTRTRMLDDTLILFCSDHGDMLGERGLWFKMNFFEGSARVPLMIAGPGIAPGLHLTPTSNLDVTPTLADLAGISLEEVRPWTDGVSLVPMVNGVERTEPVLMEYAAEASYAPLVAIREGKWKYVYCALDPEQLFDLEADPLELTNLAENPRGPVDQATLTAFRDMRAAHWDMEAFDAAVRESQARRWVVYEALRNGAYYPWDHQPLQKASERYMRNHMNLDTLEESKRYPRGE 6fo0 N 4.10 BS01 III V 1 H279 D281 T283 Y284 G285 G286 H278 D280 T282 Y283 G284 G285 P31800 ATYAQALQSVPETQVSQLDNGLRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFVEHLAFKGTKNRPGNALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIEKERDVILQELQENDTSMRDVVFNYLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSRHYKAPRMVLAAAGGLEHRQLLDLAQKHFSGLSGTYDEDAVPTLSPCRFTGSQICHREDGLPLAHVAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAATNKLCQSFQTFNICYADTGLLGAHFVCDHMSIDDMMFVLQGQWMRLCTSATESEVLRGKNLLRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDARVVREVCSKYFYDQCPAVAGFGPIEQLPDYNRIRSGMFWL 6fo0 O 4.10 BS01 III V 1 R70 L71 S74 T86 I89 E90 G94 K95 L96 S97 V98 T99 S100 T101 D147 A151 A157 I160 L176 Y177 Q276 A311 F312 N313 D380 R49 L50 S53 T65 I68 E69 G73 K74 L75 S76 V77 T78 S79 T80 D126 A130 A136 I139 L155 Y156 Q251 A286 F287 N288 D355 P23004 QDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFLLNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHAAAYRNALANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVLKQVAEQFLNIRLSGAKAKYHGGEIREQNGDSLVHAALVAESAAIGSAEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHEPFDVSAFNASYSDSGLFGFYTISQAASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRKSMAASGNLGHTPFIDEL 6fo0 P 4.10 BS01 HEM P 1 Q44 I45 G48 L49 L51 Y55 R80 H83 A84 A127 G130 L133 P134 F179 H182 F183 P186 E271 Q35 I36 G39 L40 L42 Y46 R71 H74 A75 A118 G121 L124 P125 F170 H173 F174 P177 E262 P00157 LMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLLKW 6fo0 P 4.10 BS02 HEM P 2 W31 G34 L37 H97 V98 R100 S106 W113 G116 L119 I189 H196 L197 L200 S205 N206 W22 G25 L28 H88 V89 R91 S97 W104 G107 L110 I180 H187 L188 L191 S196 N197 P00157 LMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLLKW 6fo0 P 4.10 BS03 G8U P 1 F18 L21 S35 G38 I42 M194 L197 F220 D228 F9 L12 S26 G29 I33 M185 L188 F211 D219 P00157 LMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLLKW 6fo0 Q 4.10 BS01 HEC Q 1 V36 C37 C40 H41 N105 P110 L113 Y126 L131 F153 I158 M160 P163 V35 C36 C39 H40 N104 P109 L112 Y125 L130 F152 I157 M159 P162 P00125 DLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEDEAKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYNEVLEFDDGTPATMSQVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLLPLVYAMKRHKWSVLKSRKLAYRPP 6fo0 A 4.10 BS01 III I 1 H279 D281 T283 Y284 G285 G286 L290 H278 D280 T282 Y283 G284 G285 L289 P31800 ATYAQALQSVPETQVSQLDNGLRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFVEHLAFKGTKNRPGNALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIEKERDVILQELQENDTSMRDVVFNYLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSRHYKAPRMVLAAAGGLEHRQLLDLAQKHFSGLSGTYDEDAVPTLSPCRFTGSQICHREDGLPLAHVAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAATNKLCQSFQTFNICYADTGLLGAHFVCDHMSIDDMMFVLQGQWMRLCTSATESEVLRGKNLLRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDARVVREVCSKYFYDQCPAVAGFGPIEQLPDYNRIRSGMFWL 6fo0 B 4.10 BS01 III I 1 R70 L71 S74 T86 I89 E90 G94 K95 L96 V98 T99 S100 T101 D147 A151 I160 Y177 Q276 A311 F312 N313 D380 R49 L50 S53 T65 I68 E69 G73 K74 L75 V77 T78 S79 T80 D126 A130 I139 Y156 Q251 A286 F287 N288 D355 P23004 QDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFLLNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHAAAYRNALANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVLKQVAEQFLNIRLSGAKAKYHGGEIREQNGDSLVHAALVAESAAIGSAEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHEPFDVSAFNASYSDSGLFGFYTISQAASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRKSMAASGNLGHTPFIDEL 6fo2 Q 4.40 BS01 HEC Q 1 V36 C37 C40 H41 N105 A108 L109 P110 P111 L113 R120 Y126 L131 F153 I158 M160 P163 V33 C34 C37 H38 N102 A105 L106 P107 P108 L110 R117 Y123 L128 F150 I155 M157 P160 P00125 ELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEDEAKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYNEVLEFDDGTPATMSQVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLLPLVYAMKRHKWSVLKSRKLAYRPP 6fo2 D 4.40 BS01 HEC D 1 V36 C37 C40 H41 N105 L109 P110 P111 L113 Y126 F153 I158 M160 P163 V33 C34 C37 H38 N102 L106 P107 P108 L110 Y123 F150 I155 M157 P160 P00125 ELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEDEAKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYNEVLEFDDGTPATMSQVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLLPLVYAMKRHKWSVLKSRKLAYRPP 6fo6 C 4.10 BS01 HEM C 1 Q44 I45 G48 L49 V66 R80 H83 A84 A87 F91 A127 G130 L133 P134 F179 H182 F183 P186 Q35 I36 G39 L40 V57 R71 H74 A75 A78 F82 A118 G121 L124 P125 F170 H173 F174 P177 P00157 LMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLLKW 6fo6 C 4.10 BS02 HEM C 2 W31 G34 S35 L37 L94 H97 V98 R100 S106 W113 G116 L119 L120 I189 A193 H196 L197 L200 S205 N206 W22 G25 S26 L28 L85 H88 V89 R91 S97 W104 G107 L110 L111 I180 A184 H187 L188 L191 S196 N197 P00157 LMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLLKW 6fo6 C 4.10 BS03 DY2 C 1 F18 S35 G38 I39 L197 H201 F220 I229 A232 F9 S26 G29 I30 L188 H192 F211 I220 A223 P00157 LMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISSDVDKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILALIPLLHTSKQRSMMFRPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLLKW 6fo6 D 4.10 BS01 HEC D 1 V36 C37 C40 H41 N105 A108 L109 P110 P111 L113 R120 L130 L131 F153 M160 P163 V33 C34 C37 H38 N102 A105 L106 P107 P108 L110 R117 L127 L128 F150 M157 P160 P00125 ELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEDEAKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYNEVLEFDDGTPATMSQVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLLPLVYAMKRHKWSVLKSRKLAYRPP