5kof B 2.40 BS01 6W5 C 1 C163 M204 G205 A206 V270 H298 T300 T302 V304 G305 H333 F390 F392 C163 M204 G205 A206 V270 H298 T300 T302 V304 G305 H333 F390 F392 2.3.1.41 MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVMRKLK 5kof A 2.40 BS01 6W5 D 1 C163 V270 H298 T300 T302 G305 H333 F390 F392 C164 V271 H299 T301 T303 G306 H334 F391 F393 2.3.1.41 AMKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVMRKLKD 5my0 A 2.94 BS01 COA A 1 H580 S581 C642 N644 T650 V675 L766 V770 R787 H580 S581 C642 N644 T650 V675 L766 V770 R787 2.3.1.85,2.3.1.38,2.3.1.39,2.3.1.41,1.1.1.100,4.2.1.59,1.3.1.39 29328619 SEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPN 5my0 C 2.94 BS01 MLC C 1 M499 H580 S581 M620 C642 N644 T650 F671 F682 L766 A769 R773 M499 H580 S581 M620 C642 N644 T650 F671 F678 L762 A765 R769 2.3.1.85,2.3.1.38,2.3.1.39,2.3.1.41,1.1.1.100,4.2.1.59,1.3.1.39 29328619 SEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFATGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPN 5my0 D 2.94 BS01 COA D 1 M499 H580 S581 M620 A622 N644 D647 T648 T650 F671 K673 V675 L766 A769 R773 M499 H580 S581 M620 A622 N644 D647 T648 T650 F671 K673 V675 L766 A769 R773 2.3.1.85,2.3.1.38,2.3.1.39,2.3.1.41,1.1.1.100,4.2.1.59,1.3.1.39 29328619 SEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPN 5n5e e 2.03 BS01 FE e 1 E32 E62 H65 E31 E61 H64 GLSINPTLINRDKPYTKEELMEILRLAIIAELDAINLYEQMARYSEDENVRKILLDVAREEKAHVGEFMALLLNLDPEQVTELKGGFEEVKELTGIEA 5nju A 2.10 BS02 MG A 1 V35 R37 V257 V31 R33 V253 GETLGEKWKARLNQMSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVDRGYLQPYGKVIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFHMAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMMETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRPVKYEEDVNLGSGTR 5nju B 2.10 BS02 MG B 1 Q199 G205 L206 N228 T229 S232 Q181 G187 L188 N210 T211 S214 GETLGEKWKARLNQMSALEFYSYKKSGITEVCRGHAVSRGSAKLRWLVDRGYLQPYGKVIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPVLVQSYGWNIVRLKSGVDVFHMAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMMETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRPVKYEEDVNLGSGTR 5nnm A 1.90 BS01 CO3 A 1 D26 F27 N30 D26 F27 N30 29133814 LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPR 5nnm B 1.90 BS01 CO3 B 1 L1 F5 L1 F5 29133814 LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLV 5nnt A 2.21 BS01 DPV A 1 F5 F6 F5 F6 29133814 LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPR 5nnt A 2.21 BS02 DPV B 1 R23 I24 F27 R23 I24 F27 29133814 LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPR 5nnt B 2.21 BS01 DPV A 1 R23 I24 F27 L28 R23 I24 F27 L28 29133814 LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVP 5nnt B 2.21 BS02 DPV B 1 D4 F5 F6 D4 F5 F6 29133814 LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVP 5nws A 2.23 BS01 HEM A 1 I115 L116 H123 R127 T263 L264 A267 G268 T271 S272 L275 M308 V314 A317 R318 R320 L343 G374 F375 G376 H380 C382 L383 G384 A388 I75 L76 H83 R87 T223 L224 A227 G228 T231 S232 L235 M268 V274 A277 R278 R280 L303 G334 F335 G336 H340 C342 L343 G344 A348 29327817 AGPHMMDPDLLADPFTGYGRLRERGPVVRGRFVDGTPVWFVTRYDDVRAVLRDPRFVNTPSNVPEPLRVYLLGSILDSDPPDHPRLRRLVTRAFAARRILGLRPGIERIADRLLAELPRREEEDGTVDLLEHFAYPLSITVICELVGIPATDLERWREWGGDLVSMRPERLRHSFPVMIDYCHRLIEQRRAALTDDLLSELIRAQDDDGGRLSDIETVTMILTLVLAGHETSAHLIGNGTAALLTHPGQWALLRKDPALLPRAVHELMRWCGSVHVARLRYATEDLELAGTPVARGDAVQLVLVSANFDPRHYSDPDRLDITRHQEGQAENHVGFGHGIHYCLGATLARQEGEVALARLLETYPDLALADGDPEVRRARLPGSWRLDALRLRLRP 5o36 A 2.60 BS01 POL A 1 E237 S239 E61 S63 DECDGAIIGTAVKGHVAVHSDLSYWIESRYNDTWKLERAVFGEVKSCTWPETHTLWGDDVEESELIIPHTIAGPKSKHNRREGYKTQNQGPWDENGIVLDFDYCPGTKVTITEDCSKRGPSVRTTTDSGKLITDWCCRSCSLPPLRFRTENGCWYGMEIRPVMHDETTLVRSQVDAFK 5ocj A 1.80 BS01 9SW A 1 G39 L40 S124 P223 L227 H260 W265 G32 L33 S117 P216 L220 H253 W258 2.3.1.122,2.3.1.20 29301937 VEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNTRIWVYCGNGTPSDLGGDNIPAKFLEGLTLRTNQTFRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNG 5ocj B 1.80 BS01 9SW B 1 G39 L40 S124 I222 P223 F226 L227 H260 W265 G34 L35 S119 I217 P218 F221 L222 H255 W260 2.3.1.122,2.3.1.20 29301937 LPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNTRIWVYCGNGTPSDLGGDNIPAKFLEGLTLRTNQTFRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNG 5oja A 1.35 BS01 HEM A 1 I39 K42 F43 H64 T67 V68 A71 L72 L89 S92 H93 H97 I99 Y103 L104 F138 I40 K43 F44 H65 T68 V69 A72 L73 L90 S93 H94 H98 I100 Y104 L105 F139 29309143 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPEILEKFDDLKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFFSEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGY 5ojb A 1.54 BS01 HEM A 1 L32 I39 F43 H64 T67 V68 L72 L89 S92 H93 H97 I99 Y103 L104 F107 F138 L33 I40 F44 H65 T68 V69 L73 L90 S93 H94 H98 I100 Y104 L105 F108 F139 29309143 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPEILEKFDDLKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFFSEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ojc A 1.25 BS01 HEM A 1 I39 K42 F43 T67 L68 A71 L72 L89 S92 H93 I99 H103 L104 F107 F138 I40 K43 F44 T68 L69 A72 L73 L90 S93 H94 I100 H104 L105 F108 F139 29309143 MVLSEGEWQLVLHVWAKVEADVAGHGQDTLIRLFKSHPEILEKFDGLKHLKTEAEMKASEDLKEHGVTLLTALGAILKKKGHHEAELKPLAQSHAAKHKIPIKHLEFFSEAIIHVLHSRHPGDFGADAQGAMNKALELFRTDIAAKYKELGYQG 5oyn A 2.70 BS01 MG A 1 E92 D129 K130 E463 E90 D127 K128 E461 NRTPRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNRIHLDLVQRVRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVETLHGYPIDAVVLTTGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHENELVGSGTVIWRSRRKLAAGEITEEEFIDRAASSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTGQRIVDLAYDDVKPLDILTKQAFENAIALVAAAGGSTNAQPHIVAMARHAGVEITADDWRAAYDIPLIVNMQPAGKYLGERFHRAGGAPAVLWELLQQGRLHGDVLTVTGKTMSENLQGRETSDREVIFPYHEPLAEKAGFLVLKGNLFDFAIMKSSVIGEEFRKRYLSQPGQEGVFEARAIVFDGSDDYHKRINDPALEIDERCILVIRGAGPIGWPGSAEVVNMQPPDHLLKKGIMSLPTLGDGRQSGTADSPSILNASPESAIGGGLSWLRTGDTIRIDLNTGRCDALVDEATIAARKQDGIPAVPATMTPWQEIYRAHASQLDTGGVLEFAVKYQDLAAKLPRHNH 5oyn A 2.70 BS02 FES A 1 C60 F91 N93 C128 D129 H200 C201 A207 C58 F89 N91 C126 D127 H198 C199 A205 NRTPRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNRIHLDLVQRVRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVETLHGYPIDAVVLTTGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHENELVGSGTVIWRSRRKLAAGEITEEEFIDRAASSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTGQRIVDLAYDDVKPLDILTKQAFENAIALVAAAGGSTNAQPHIVAMARHAGVEITADDWRAAYDIPLIVNMQPAGKYLGERFHRAGGAPAVLWELLQQGRLHGDVLTVTGKTMSENLQGRETSDREVIFPYHEPLAEKAGFLVLKGNLFDFAIMKSSVIGEEFRKRYLSQPGQEGVFEARAIVFDGSDDYHKRINDPALEIDERCILVIRGAGPIGWPGSAEVVNMQPPDHLLKKGIMSLPTLGDGRQSGTADSPSILNASPESAIGGGLSWLRTGDTIRIDLNTGRCDALVDEATIAARKQDGIPAVPATMTPWQEIYRAHASQLDTGGVLEFAVKYQDLAAKLPRHNH 5oyn B 2.70 BS01 MG B 1 E92 D129 K130 T206 E463 E90 D127 K128 T204 E461 NRTPRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNRIHLDLVQRVRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVETLHGYPIDAVVLTTGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHENELVGSGTVIWRSRRKLAAGEITEEEFIDRAASSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTGQRIVDLAYDDVKPLDILTKQAFENAIALVAAAGGSTNAQPHIVAMARHAGVEITADDWRAAYDIPLIVNMQPAGKYLGERFHRAGGAPAVLWELLQQGRLHGDVLTVTGKTMSENLQGRETSDREVIFPYHEPLAEKAGFLVLKGNLFDFAIMKSSVIGEEFRKRYLSQPGQEGVFEARAIVFDGSDDYHKRINDPALEIDERCILVIRGAGPIGWPGSAEVVNMQPPDHLLKKGIMSLPTLGDGRQSGTADSPSILNASPESAIGGGLSWLRTGDTIRIDLNTGRCDALVDEATIAARKQDGIPAVPATMTPWQEIYRAHASQLDTGGVLEFAVKYQDLAAKLPRHNH 5oyn B 2.70 BS02 FES B 1 C60 N93 C128 D129 H200 C201 A207 C58 N91 C126 D127 H198 C199 A205 NRTPRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNRIHLDLVQRVRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVETLHGYPIDAVVLTTGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHENELVGSGTVIWRSRRKLAAGEITEEEFIDRAASSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTGQRIVDLAYDDVKPLDILTKQAFENAIALVAAAGGSTNAQPHIVAMARHAGVEITADDWRAAYDIPLIVNMQPAGKYLGERFHRAGGAPAVLWELLQQGRLHGDVLTVTGKTMSENLQGRETSDREVIFPYHEPLAEKAGFLVLKGNLFDFAIMKSSVIGEEFRKRYLSQPGQEGVFEARAIVFDGSDDYHKRINDPALEIDERCILVIRGAGPIGWPGSAEVVNMQPPDHLLKKGIMSLPTLGDGRQSGTADSPSILNASPESAIGGGLSWLRTGDTIRIDLNTGRCDALVDEATIAARKQDGIPAVPATMTPWQEIYRAHASQLDTGGVLEFAVKYQDLAAKLPRHNH 5oyn C 2.70 BS02 FES C 1 C60 E92 N93 C128 D129 H200 C201 A207 C57 E89 N90 C125 D126 H197 C198 A204 RTPRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNRIHLDLVQRVRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVETLHGYPIDAVVLTTGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHENELVGSGTVIWRSRRKLAAGEITEEEFIDRAASSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTGQRIVDLAYDDVKPLDILTKQAFENAIALVAAAGGSTNAQPHIVAMARHAGVEITADDWRAAYDIPLIVNMQPAGKYLGERFHRAGGAPAVLWELLQQGRLHGDVLTVTGKTMSENLQGRETSDREVIFPYHEPLAEKAGFLVLKGNLFDFAIMKSSVIGEEFRKRYLSQPGQEGVFEARAIVFDGSDDYHKRINDPALEIDERCILVIRGAGPIGWPGSAEVVNMQPPDHLLKKGIMSLPTLGDGRQSGTADSPSILNASPESAIGGGLSWLRTGDTIRIDLNTGRCDALVDEATIAARKQDGIPAVPATMTPWQEIYRAHASQLDTGGVLEFAVKYQDLAAKLPRHNH 5ur4 A 1.52 BS01 PYV A 1 I62 V81 V83 A89 S92 E94 I110 H115 L117 Y120 F159 V163 I62 V81 V83 A89 S92 E94 I110 H115 L117 Y120 F150 V154 MPSELTPEERSELKNSIAEFHTYQLDPGSCSSLHAQRIHAPPELVWSIVRRFDKPQTYKHFIKSCSVEQNFEMRVGCTRDVIVISGLPANTSTERLDILDDERRVTGFSIIGGEHRLTNYKSVTTVHRFEKENRIWTVVLESYVVDMRMFADTVVKLNLQKLATVAEAMARN 5vns A 1.45 BS01 DH9 A 1 G39 L40 S124 M125 S148 F150 L161 I162 A165 T213 L227 E228 H260 G39 L40 S124 M125 S148 F150 L161 I162 A165 T213 L221 E222 H254 2.3.1.122,2.3.1.20 FSRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNTRIWVYCGNGTPSIPAKFLEGLTLRTNQTFRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNG 5w21 A 3.00 BS01 ZN A 1 D426 C739 D745 D815 D375 C688 D694 D764 3.2.1.31 EPGDGAQTWARFSRPPAPEAAGLFQGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPPLQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINPRRMTDHSIKECQKSLDFVLGWFAKPVFIDGDYPESMKNNLSSILPDFTESEKKFIKGTADFFALCFGPTLSFQLLDPHMKFRQLESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQKDKEVAERVLEFDIGWLAEPIFGSGDYPWVMRDWLNQRNNFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDITWLNSPSQVAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDRTAPRFGLYRYAADQFEPKASMKHYRKIIDSNGFPGPRFCPEEFTVCTECSFFH 5wzm A 2.00 BS01 CA A 1 D22 Y23 G24 Y111 N113 D20 Y21 G22 Y109 N111 3.1.1.4 28883454 VQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC 5wzm A 2.00 BS02 CA A 2 Y26 G28 I29 G30 D47 Y24 G26 I27 G28 D45 3.1.1.4 28883454 VQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC 5wzo A 1.90 BS02 CA A 2 D22 Y23 G24 H110 Y111 D22 Y23 G24 H110 Y111 3.1.1.4 28883454 NLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC 5wzs A 2.30 BS01 7W9 A 1 L2 F5 G6 I9 A17 Y20 N21 Y26 C27 G28 G30 C43 H46 D47 F97 L2 F5 G6 I9 A17 Y20 N21 Y26 C27 G28 G30 C43 H46 D47 F97 3.1.1.4 28883454 NLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC 5wzs A 2.30 BS02 CA A 1 Y26 G28 G30 D47 Y26 G28 G30 D47 3.1.1.4 28883454 NLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC 5wzt A 2.40 BS02 7W6 A 1 L2 F5 G6 I9 A17 L18 Y20 N21 Y26 C27 G28 I29 G30 C43 H46 D47 K61 F97 L2 F5 G6 I9 A17 L18 Y20 N21 Y26 C27 G28 I29 G30 C43 H46 D47 K61 F97 3.1.1.4 28883454 NLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC 5wzv A 2.20 BS02 7W0 A 1 L2 F5 G6 A17 L18 Y20 N21 Y26 C27 G28 G30 C43 H46 D47 L2 F5 G6 A17 L18 Y20 N21 Y26 C27 G28 G30 C43 H46 D47 3.1.1.4 28883454 NLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC 5wzw A 1.95 BS02 U8D A 1 L2 F5 G6 I9 Y20 N21 Y26 C27 G28 I29 G30 C43 H46 D47 K61 F97 L2 F5 G6 I9 Y20 N21 Y26 C27 G28 I29 G30 C43 H46 D47 K61 F97 3.1.1.4 28883454 NLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC 5x02 A 2.40 BS01 F6M A 1 L616 V624 A642 K644 V675 F691 E692 Y693 C694 C695 Y696 G697 L818 H821 C828 D829 F830 L44 V52 A70 K72 V103 F119 E120 Y121 C122 C123 Y124 G125 L176 H179 C186 D187 F188 2.7.10.1 ESQLQMVQVTGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFSVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQL 5x06 E 3.24 BS01 ADP E 1 E17 S21 F22 W23 G53 A54 G55 R56 S57 H58 L165 A173 R177 F205 E13 S17 F18 W19 G49 A50 G51 R52 S53 H54 L161 A169 R173 F197 AQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFDVGRFLLKRLDREMRTLFMTLDQLDRASITALTIPFVKEIL 5x06 F 3.24 BS01 ADP F 1 E17 S21 F22 W23 G53 G55 R56 S57 H58 L165 R177 M201 R202 F205 E14 S18 F19 W20 G50 G52 R53 S54 H55 L162 R174 M198 R199 F202 PAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEIL 5x06 H 3.24 BS01 ADP H 1 S21 F22 W23 G53 A54 G55 R56 S57 H58 L165 R177 R202 F205 S17 F18 W19 G49 A50 G51 R52 S53 H54 L161 R173 R185 F188 AQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLGRFLLREMRTLFMTL 5x3r A 2.10 BS01 7Y3 A 1 F75 W114 N133 N136 Q137 V140 A163 N164 F166 H167 C170 F73 W112 N131 N134 Q135 V138 A161 N162 F164 H165 C168 SIAKRPRTRLSPLKRKQQLMEIALEVFARRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDEVLNHVVRQFSNFLSDNIDLDLHAKENIANITNAMIELVVQDNHWLKVWFEWSASTRDEVWPLFVTTNRTNQLLVQNMFIKAIERGEVCDQHNPEDLANLFHGICYSLFVQANRTNNTAELSKLVSSYLDMLCIYKREHE 5xjd A 2.22 BS01 87L B 1 F366 K369 V382 F149 K152 V165 28515457 RSIASSKLWMLEFSAFLERQQDPDTYNKHLFVHISQDPYLETVDIRQIYDKFPEKKGGLKELFERGPSNAFFLVKFWADLNTNIDGSAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVK 5xjd B 2.22 BS01 87L B 1 F330 F366 K369 L370 V382 F115 F151 K154 L155 V167 28515457 MRSIASSKLWMLEFSAFLERQQDPDTYNKHLFVHISQPYLETVDIRQIYDKFPEKKGGLKELFERGPSNAFFLVKFWADLNTNIDDEGSAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE 5xm8 A 2.55 BS01 NUC E 1 Y22 N23 C81 G82 E83 R84 K85 V120 I124 R127 K131 K136 L137 N138 Q139 Y140 Y25 N26 C84 G85 E86 R87 K88 V123 I127 R130 K134 K139 L140 N141 Q142 Y143 2.7.7.7 29222499 GGSMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm8 A 2.55 BS02 NUC F 1 G38 R42 D49 D51 K79 K85 Q98 D100 H115 F116 T117 V120 L123 R127 G41 R45 D52 D54 K82 K88 Q101 D103 H118 F119 T120 V123 L126 R130 2.7.7.7 29222499 GGSMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm8 B 2.55 BS01 NUC E 1 R42 D49 K85 H115 F116 T117 G118 V120 L123 R43 D50 K86 H116 F117 T118 G119 V121 L124 2.7.7.7 29222499 SMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm8 B 2.55 BS02 NUC F 1 V80 C81 G82 E83 R84 K85 I124 R127 A128 K131 K136 L137 N138 Q139 Y140 V81 C82 G83 E84 R85 K86 I125 R128 A129 K132 K137 L138 N139 Q140 Y141 2.7.7.7 29222499 SMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm8 C 2.55 BS01 NUC G 1 V80 C81 G82 E83 R84 K85 I124 R127 K131 K136 L137 N138 Y140 V83 C84 G85 E86 R87 K88 I127 R130 K134 K139 L140 N141 Y143 2.7.7.7 29222499 GGSMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm8 C 2.55 BS02 NUC H 1 G38 R42 D49 D51 Q98 D100 H115 F116 T117 V120 G41 R45 D52 D54 Q101 D103 H118 F119 T120 V123 2.7.7.7 29222499 GGSMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm8 D 2.55 BS01 NUC G 1 R42 D49 D51 H115 F116 T117 G118 V120 L123 R43 D50 D52 H116 F117 T118 G119 V121 L124 2.7.7.7 29222499 SMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm9 A 3.05 BS02 NUC F 1 G38 D49 N51 K79 K85 Q98 H115 F116 T117 G118 V120 R127 G38 D49 N51 K79 K85 Q98 H115 F116 T117 G118 V120 R127 2.7.7.7 29222499 MLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVNLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm9 B 3.05 BS01 NUC E 1 D49 N51 K85 H115 F116 T117 G118 V120 L123 D49 N51 K85 H115 F116 T117 G118 V120 L123 2.7.7.7 29222499 MLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVNLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm9 C 3.05 BS02 NUC H 1 D49 N51 K79 K85 Q98 H115 F116 T117 G118 V120 D49 N51 K79 K85 Q98 H115 F116 T117 G118 V120 2.7.7.7 29222499 MLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVNLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xm9 D 3.05 BS01 NUC G 1 H115 F116 V120 L123 H115 F116 V120 L123 2.7.7.7 29222499 MLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVNLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xma A 3.80 BS01 NUC E 1 N23 V80 C81 G82 E83 R84 K85 R127 K131 L137 N138 Q139 Y140 N23 V80 C81 G82 E83 R84 K85 R127 K131 L137 N138 Q139 Y140 2.7.7.7 29222499 MLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xma A 3.80 BS02 NUC F 1 G38 R42 D49 D51 Q98 D100 H115 F116 T117 G118 G38 R42 D49 D51 Q98 D100 H115 F116 T117 G118 2.7.7.7 29222499 MLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xma B 3.80 BS01 NUC E 1 D51 Q98 D100 H115 F116 G118 V120 L123 D51 Q98 D100 H115 F116 G118 V120 L123 2.7.7.7 29222499 MLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQLDLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL 5xnp A 3.73 BS01 CA A 1 N205 K206 N192 K193 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHI 5xnp A 3.73 BS02 CA A 2 S139 S140 S126 S127 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHI 5xnp A 3.73 BS03 CA A 3 H93 D117 H80 D104 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHI 5xnp A 3.73 BS04 CA A 4 P17 D50 R52 P4 D37 R39 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHI 5xnp A 3.73 BS05 CA A 5 H126 E150 H113 E137 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHI 5xnp A 3.73 BS06 CA A 6 A366 T367 A353 T354 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHI 5xnp A 3.73 BS07 CA B 1 F62 T64 T86 F49 T51 T73 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHI 5xnp B 3.73 BS01 CA A 1 T64 T86 T51 T73 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHI 5xnp B 3.73 BS02 CA B 1 N205 K206 G239 N192 K193 G226 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHI 5xnq A 2.80 BS02 CA A 2 R102 H127 R89 H114 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPGDPESNPAGE 5xnq A 2.80 BS03 CA A 3 H193 H195 H180 H182 PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPGDPESNPAGE 5xrl A 2.00 BS01 GOL A 1 H53 V63 A65 W72 Q75 H52 V62 A64 W71 Q74 29293962 SLLPVPYTEAASLSTGSTVTIKGRPLACFLNEPYLQVDFHTEMKEESDIVFHFQVCFGRRVVMASREYGAWKQQVESKNMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHRIKPEAVKMVQVWRDISLTKFNVSYLK 5xrn A 1.60 BS01 GOL A 1 H53 Q55 V63 N65 W72 Q75 H52 Q54 V62 N64 W71 Q74 29293962 SLLPVPYTEAASLSTGSTVTIKGRPLACFLNEPYLQVDFHTEMKEESDIVFHFQVCFGRRVVMNSREYGAWAQQVESKNMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHRIKPEAVKMVQVWRDISLTKFNVSYLKR 5xro A 1.60 BS01 GOL A 1 H53 N65 W72 Q75 H52 N64 W71 Q74 29293962 SLLPVPYTEAASLSTGSTVTIKGRPLACFLNEPYLQVDFHTEMKEESDIVFHFQVCFGRRVVMNSREYGAWKAQVESKNMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHRIKPEAVKMVQVWRDISLTKFNVSYLKR 5xu1 A 3.30 BS01 MG A 1 G44 S45 K47 G38 S39 K41 KQLISLKNIFRSYELQVLKNINLEVNEGEFVAIMGPSGSGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLNALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALVNNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRDGVISSDSAQ 5xu1 B 3.30 BS01 MG B 1 G46 K47 S48 G45 K46 S47 KQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSGSGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLNALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALVNNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRDGVISSDSAQ 5y0v A 2.42 BS01 BER A 1 V327 W448 W483 V484 W490 V305 W426 W461 V462 W468 3.2.1.52 EDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTDHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERFVRMGIQAESLQPEWCYQNEGYCYS 5y0v A 2.42 BS02 NAG A 1 N375 L391 D392 K393 N353 L369 D370 K371 3.2.1.52 EDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTDHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERFVRMGIQAESLQPEWCYQNEGYCYS 5y1b A 2.21 BS02 8KL A 1 V327 D367 W448 Y475 V484 W490 V305 D345 W426 Y453 V462 W468 3.2.1.52 EDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTLHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERFVRMGIQAESLQPEWCYQNEGYCYS 5y20 A 2.41 BS01 III P 1 T5 Y14 N16 D17 F19 W20 I21 C22 D24 E27 W29 I45 K46 T2 Y11 N13 D14 F16 W17 I18 C19 D21 E24 W26 I42 K43 DTLCGSCGGNYTNDEFWICCDVCERWYHGKCVKITPAKAESIKQYKCPSCCT 5y20 A 2.41 BS02 ZN A 1 C7 C10 H31 C34 C4 C7 H28 C31 DTLCGSCGGNYTNDEFWICCDVCERWYHGKCVKITPAKAESIKQYKCPSCCT 5y20 A 2.41 BS03 ZN A 2 C23 C26 C50 C53 C20 C23 C47 C50 DTLCGSCGGNYTNDEFWICCDVCERWYHGKCVKITPAKAESIKQYKCPSCCT 5y5y A 4.70 BS01 ADP A 1 G231 S232 G233 K234 T235 V236 F419 N498 A499 Y500 G231 S232 G233 K234 T235 V236 F419 N498 A499 Y500 3.6.3.14 29311594 MIQGVIQKIAGPAVIAKGMLGARMYDICKVGEEGLVGEIIRLDGDTAFVQVYEDTSGLKVGEPVVSTGLPLAVELGPGMLNGIYDGIQRPLERIREKTGIYITRGVVVHALDREKKWAWTPMVKPGDEVRGGMVLGTVPEFGFTHKILVPPDVRGRVKEVKPAGEYTVEEPVVVLEDGTELKMYHTWPVRRARPVQRKLDPNTPFLTGMRILDVLFPVAMGGTAAIPGPFGSGKTVTQQSLAKWSNADVVVYVGCGERGNEMTDVLVEFPELTDPKTGGPLMHRTVLIANTSNMPVAAREASIYVGVTIAEYFRDQGFSVALMADSTSRWAEALREISSRLEEMPAEEGYPPYLAARLAAFYERAGKVITLGGEEGAVTIVGAVSPPGGDMSEPVTQSTLRIVGAFWRLDASLAFRRHFPAINWNGSYSLFTSALDPWYRENVAEDYPELRDAISELLQREAGLQEIVQLVGPDALQDAERLVIEVGRIIREDFLQQNAYHEVDAYCSMKKAYGIMKMILAFYKEAEAAIKRGVSIDEILQLPVLERIGRARYVSEEEFPAYFEEAMKEIQGAFKAL 5y5y C 4.70 BS01 ADP C 1 F230 G231 S232 G233 K234 T235 V236 R417 H418 F419 F230 G231 S232 G233 K234 T235 V236 R417 H418 F419 3.6.3.14 29311594 MIQGVIQKIAGPAVIAKGMLGARMYDICKVGEEGLVGEIIRLDGDTAFVQVYEDTSGLKVGEPVVSTGLPLAVELGPGMLNGIYDGIQRPLERIREKTGIYITRGVVVHALDREKKWAWTPMVKPGDEVRGGMVLGTVPEFGFTHKILVPPDVRGRVKEVKPAGEYTVEEPVVVLEDGTELKMYHTWPVRRARPVQRKLDPNTPFLTGMRILDVLFPVAMGGTAAIPGPFGSGKTVTQQSLAKWSNADVVVYVGCGERGNEMTDVLVEFPELTDPKTGGPLMHRTVLIANTSNMPVAAREASIYVGVTIAEYFRDQGFSVALMADSTSRWAEALREISSRLEEMPAEEGYPPYLAARLAAFYERAGKVITLGGEEGAVTIVGAVSPPGGDMSEPVTQSTLRIVGAFWRLDASLAFRRHFPAINWNGSYSLFTSALDPWYRENVAEDYPELRDAISELLQREAGLQEIVQLVGPDALQDAERLVIEVGRIIREDFLQQNAYHEVDAYCSMKKAYGIMKMILAFYKEAEAAIKRGVSIDEILQLPVLERIGRARYVSEEEFPAYFEEAMKEIQGAFKAL 5y6d D 2.10 BS03 8PL D 1 Y67 W87 H114 H116 D118 H179 C198 R205 N210 H240 Y36 W56 H83 H85 D87 H148 C167 R174 N179 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5y6k A 2.86 BS02 8R6 A 1 D63 R124 Y188 K206 K296 D61 R122 Y186 K204 K294 29323384 DKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPCKPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGLVPVLAENYNAGYFAIAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQQQHLFGSNSETKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAVGNLRKCSTSSLLEACTFRRP 5y6k A 2.86 BS03 8R6 A 2 R602 Q603 R584 Q585 29323384 DKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPCKPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGLVPVLAENYNAGYFAIAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQQQHLFGSNSETKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAVGNLRKCSTSSLLEACTFRRP 5y6q A 2.50 BS01 FES A 1 K41 G42 C43 D44 G46 Q47 C48 G49 C51 C63 K39 G40 C41 D42 G44 Q45 C46 G47 C49 C61 29319807 ERISLTMQVNGQPYPMEIDPRVTLLDALREHLNLTGTKKGCDQGQCGACTVLVNGQRVLSCLTLAAQADGAEVTSIEGLQSASGELHPVQRCFVENDAFQCGYCTPGQIMSAVACIKEGHAGSDDEIREYMSGNLCRCGAYPHIIDAIKQAAAEMAK 5y6q A 2.50 BS02 FES A 2 Q102 C103 G104 C106 C138 R139 C140 Q100 C101 G102 C104 C136 R137 C138 29319807 ERISLTMQVNGQPYPMEIDPRVTLLDALREHLNLTGTKKGCDQGQCGACTVLVNGQRVLSCLTLAAQADGAEVTSIEGLQSASGELHPVQRCFVENDAFQCGYCTPGQIMSAVACIKEGHAGSDDEIREYMSGNLCRCGAYPHIIDAIKQAAAEMAK 5y6q A 2.50 BS03 FAD B 1 G46 Q47 G44 Q45 29319807 ERISLTMQVNGQPYPMEIDPRVTLLDALREHLNLTGTKKGCDQGQCGACTVLVNGQRVLSCLTLAAQADGAEVTSIEGLQSASGELHPVQRCFVENDAFQCGYCTPGQIMSAVACIKEGHAGSDDEIREYMSGNLCRCGAYPHIIDAIKQAAAEMAK 5y6q A 2.50 BS04 MCN C 1 Q102 C140 Q100 C138 29319807 ERISLTMQVNGQPYPMEIDPRVTLLDALREHLNLTGTKKGCDQGQCGACTVLVNGQRVLSCLTLAAQADGAEVTSIEGLQSASGELHPVQRCFVENDAFQCGYCTPGQIMSAVACIKEGHAGSDDEIREYMSGNLCRCGAYPHIIDAIKQAAAEMAK 5y6q B 2.50 BS01 FAD B 1 I26 A28 G29 G30 T31 T32 Q33 I50 M74 A97 A98 I102 A106 T107 G110 N111 R113 Q114 R115 G164 D165 I213 I214 K232 Y239 E240 F241 I26 A28 G29 G30 T31 T32 Q33 I50 M74 A97 A98 I102 A106 T107 G110 N111 R113 Q114 R115 G164 D165 I213 I214 K232 Y239 E240 F241 29319807 MNPFHWKVAQSASEAAALKQQSGSQILAGGTTQLDLMKCGVFNPPQLIGINGLSELRSLSFDNDKISAGALITMSQLADHPDCQQHAPAIYGSLWQAASPQIRNMATLGGNLRQRTRCAYYRDPATFSACNKRNPGSGCAARQGVNSNHAILGASDSCIAVYPGDLAVALVAFDAVVIVQNPQGETRRIAIDDFFLLPGETPDQEHDLRDDEIIVAIEVPQTASLQRSHYLKVRDRSSYEFAAASAAAGFTLENGVMRQVHIALGGVATKPWRATRVEQALEGQPFNEETVFQAAELINQETQALEHNAYKVKLAPRVIARALMAAGEIA 5y6q B 2.50 BS02 SF4 B 1 C118 Y121 C130 N131 C139 A140 A141 S157 C158 I159 A160 C118 Y121 C130 N131 C139 A140 A141 S157 C158 I159 A160 29319807 MNPFHWKVAQSASEAAALKQQSGSQILAGGTTQLDLMKCGVFNPPQLIGINGLSELRSLSFDNDKISAGALITMSQLADHPDCQQHAPAIYGSLWQAASPQIRNMATLGGNLRQRTRCAYYRDPATFSACNKRNPGSGCAARQGVNSNHAILGASDSCIAVYPGDLAVALVAFDAVVIVQNPQGETRRIAIDDFFLLPGETPDQEHDLRDDEIIVAIEVPQTASLQRSHYLKVRDRSSYEFAAASAAAGFTLENGVMRQVHIALGGVATKPWRATRVEQALEGQPFNEETVFQAAELINQETQALEHNAYKVKLAPRVIARALMAAGEIA 5y6q C 2.50 BS01 MCN C 1 G260 G261 F262 G263 R371 I488 G489 T490 G491 T492 I495 G527 G528 S529 Q530 L531 A532 R665 L666 Y667 N668 L671 A672 Q675 G737 K738 V740 G741 E742 G233 G234 F235 G236 R344 I461 G462 T463 G464 T465 I468 G500 G501 S502 Q503 L504 A505 R638 L639 Y640 N641 L644 A645 Q648 G710 K711 V713 G714 E715 29319807 GSPIEGLGAARSRGDGRVKVIGEARYAIEHQPENPLYGVVLQSTVASGRISRLSAEKALQADGVLAVYTHLNPLKINKPTAIADGGAAQSTYTPIQDDVIIHNGQNIGIVIAETFEQATWAASLVEIEYETTPARVFATDEGVEAKPMSAQDIDLGDAATAMHSAEVRINQRYTTPREYNMPMEPHACIAHWHEGQITVWEPSQWVAGAQVEIAEWLGIETEKVRIISPYVGGGFGSKPVPYTHVALASVASRALNRPVKVSLTRPQTFTGLGGRPATSQQLELGASRDGKIEAIIQRSFSETSLIDVFAENCSKVTARMYAVSNVSAQHQVRLINTVTPGWMRAPGENPSAFGLEVAMDELAYALDIDPLELRLRNWADKDYQLDLPWSTRRLKEAYQKGAEAFGWDKRIMTPRSMREGRELIGWGMASGTYPVNRLPAEAKIILTPQGRFVVQCAGADIGTGTYTILAQTAADHLGVGSETIEVELGDTALPRAGVAGGSQLAGNLTAAVNDTAKKMRERLLALASELPASPLSGLPVSQFTLQDGAIQHSGGSGLSLAQLATLAPPDSLSVKGGTFPDDMPQSERDKIVRNLNDMSRPEAFSAHSWSAQFVEVRVDEDFGTIRVKRMVAALDSGRLYNPKLARSQWIGGMIMGVGQALMEEGIVDPRNGRVINNNLADYLVPVNGDIPSITTINVGEPDFEATTMGGKAVGELGIVGVAAAISNAVFHATGKRVRGLPITLDKII 5y7r B 1.96 BS01 FE B 1 H134 D136 H211 H126 D128 H203 1.14.-.- 29314482 SQIPRLSAINDLHKIWPTVEEHGAAIIESFLSLDIVRRLNEEVDPFVKIEPIPAAKTKDHPNHVLSTTTRLVNVLAPISKAYREDVLNSKVLHRICSDAFHVYGDYWVLMGAVMELAPSNPAQPLHRDMRFSHPIVEYLKPDAPATSINFLVALSPFTAENGATHVILGSHKWQNLSNVSMDATVRALMNPGDALLITDSTIHCGGAETTGTETRRLLTITMGISQLTPLESNLAVPRPVIESLTPLAQRLLGWASQRSAAPRDIGLLTIRGNSIEKTMNLKAEQPL 5y7r B 1.96 BS02 AKG B 1 M122 Q131 H134 D136 L159 T172 H211 G213 R223 L225 M114 Q123 H126 D128 L151 T164 H203 G205 R215 L217 1.14.-.- 29314482 SQIPRLSAINDLHKIWPTVEEHGAAIIESFLSLDIVRRLNEEVDPFVKIEPIPAAKTKDHPNHVLSTTTRLVNVLAPISKAYREDVLNSKVLHRICSDAFHVYGDYWVLMGAVMELAPSNPAQPLHRDMRFSHPIVEYLKPDAPATSINFLVALSPFTAENGATHVILGSHKWQNLSNVSMDATVRALMNPGDALLITDSTIHCGGAETTGTETRRLLTITMGISQLTPLESNLAVPRPVIESLTPLAQRLLGWASQRSAAPRDIGLLTIRGNSIEKTMNLKAEQPL 5y7t B 2.05 BS03 AKG B 1 M122 L124 Q131 H134 D136 L159 T172 H211 G213 R223 L225 M114 L116 Q123 H126 D128 L151 T164 H203 G205 R215 L217 1.14.-.- 29314482 SQIPRLSAINDLHKIWPTVEEHGAAIIESFLSLDIVRRLNEEVDPFVKIEPIPAAKTKDHPNHVLSTTTRLVNVLAPISKAYREDVLNSKVLHRICSDAFHVYGDYWVLMGAVMELAPSNPAQPLHRDMRFSHPIVEYLKPDAPATSINFLVALSPFTAENGATHVILGSHKWQNLSNVSMDATVRALMNPGDALLITDSTIHCGGAETTGTETRRLLTITMGISQLTPLESNLAVPRPVIESLTPLAQRLLGWASQRSAAPRDIGLLTIRGNSIEKTMNLKAEQPL 5ybl A 2.11 BS01 MN A 1 H130 D132 H214 H119 D121 H197 1.14.11.- 29317628 LQKFPATAPADEIYAAFKEDGCVIIEGFVPPDQMARFSQEIQPAMEKIQVQVTNSNDRVKRFSKLVTTSPTFRHEILENDLMHELLQRVFSKPGEGMGYHFNDTMVIEVQPGAPAQRLHRDQELYPWWNSMGPDAPECLVNFFCAVTPFTVENGATRLVPGSNRWPELTLIDCPQYDSVPAIMQPGDCYMMSGKVIHGAGHNATLSDQRRALAFSTIRRELRPVQAFPLWIPMQIATELSPRTQAMFGFRSSVHFWGNDGKDIGEHLGLISS 5ybl A 2.11 BS02 AKG A 1 R72 I118 H130 F154 T167 H214 A216 R226 R61 I107 H119 F143 T156 H197 A199 R209 1.14.11.- 29317628 LQKFPATAPADEIYAAFKEDGCVIIEGFVPPDQMARFSQEIQPAMEKIQVQVTNSNDRVKRFSKLVTTSPTFRHEILENDLMHELLQRVFSKPGEGMGYHFNDTMVIEVQPGAPAQRLHRDQELYPWWNSMGPDAPECLVNFFCAVTPFTVENGATRLVPGSNRWPELTLIDCPQYDSVPAIMQPGDCYMMSGKVIHGAGHNATLSDQRRALAFSTIRRELRPVQAFPLWIPMQIATELSPRTQAMFGFRSSVHFWGNDGKDIGEHLGLISS 5ybl C 2.11 BS02 AKG C 1 R72 I118 Q127 F154 T167 H214 A216 R226 R60 I103 Q112 F139 T152 H184 A186 R194 1.14.11.- 29317628 SQKFPATAPADEIYAAFKEDGCVIIEGFVPPDQMARFSQEIQPAMEKIQVQVTNNDRVKRFSKLVTTSPTFRHEILENDLMHELLQRVFSKPMGYHFNDTMVIEVQPGAPAQRLHRDQELYPWWNSMGPDAPECLVNFFCAVTPFTVENGATRLVPGSNRWKIDSVPAIMQPGDCYMMSGKVIHGAGHNATDQRRALAFSTIRRELRPVQAFPLWIPMQIATELSPRTQAMFGFRSHFWGNDKDIGEHLGLI 5ybn A 2.10 BS01 FE A 1 H130 D132 H214 H133 D135 H217 29317628 LVPRGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNGNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECVINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAIMQPGDCYLMSGKVIHGAGHNATTTDRRRALALAIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSVQHCDVVHFWGNDGKDIAHHLGLI 5ybn A 2.10 BS02 AKG A 1 Q127 H130 D132 F154 T167 H214 A216 R226 Q130 H133 D135 F157 T170 H217 A219 R229 29317628 LVPRGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNGNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECVINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAIMQPGDCYLMSGKVIHGAGHNATTTDRRRALALAIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSVQHCDVVHFWGNDGKDIAHHLGLI 5ybo A 2.20 BS03 8SX B 1 C273 D276 M277 V278 C273 D275 M276 V277 29317628 LVPGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECVINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAIMQPGDCYLMSGKVIHGAGHNATTTDRRRALALAIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSVQHCVDMVHFWGNDGKDIAHHLGLI 5ybo B 2.20 BS02 AKG B 1 R72 I118 Q127 H130 F154 T167 H214 A216 R226 R74 I120 Q129 H132 F156 T169 H215 A217 R225 29317628 GLVPRGSHMPPRLQRFPASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNGNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECVINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAMQPGDCYLMSGKVIHGAGHTTTDRRRALALAIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSHFWGNDGKDIAHHLGLIS 5ybo B 2.20 BS03 8SX B 1 S66 N67 R72 N113 M116 Q127 R128 H130 D132 L135 V150 N152 A232 M241 S68 N69 R74 N115 M118 Q129 R130 H132 D134 L137 V152 N154 A231 M240 29317628 GLVPRGSHMPPRLQRFPASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNGNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECVINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAMQPGDCYLMSGKVIHGAGHTTTDRRRALALAIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSHFWGNDGKDIAHHLGLIS 5ybp A 2.31 BS03 8SX B 1 D276 M277 V278 D276 M277 V278 29317628 LVPGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECLINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAIMQPGDCYLMSGKVIHGAGHNATTTDRRRALALSIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSVQHCVDMVHFWGNDGKDIAHHLGLI 5ybp B 2.31 BS03 8SX B 1 S66 N67 R72 M116 Q127 R128 H130 D132 L150 N152 S232 M241 S67 N68 R73 M116 Q126 R127 H129 D131 L149 N151 S229 M238 29317628 GLVPRGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFEQVARFSQEVDPAMEKIPVEVTNNGNSNDRTKRFSKCVIASPFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPAPAQRLHRDQELYPWWNSMGPAGPECLINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAMQPGDCYLMSGKVIHGAGHNTTTDRRRALALSIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSFWGNDGKDIAHHLGLI 5ybq A 2.25 BS03 8T0 A 1 R72 M116 Q127 H130 D132 N152 S232 R73 M117 Q128 H131 D133 N153 S233 29317628 LVPGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECLINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAIMQPGDCYLMSGKVIHGAGHNATTTDRRRALALSIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSVQHCVDMVHFWGNDGKDIAHHLGLI 5ybq B 2.25 BS02 AKG B 1 R72 I118 Q127 H130 D132 F154 T167 H214 A216 R226 R75 I121 Q130 H133 D135 F157 T170 H216 A218 R228 29317628 GLVPRGSHMPRLQRFPATASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNGNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECLINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPIMQPGDCYLMSGKVIHGAGHNATTTDRRRALALSIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSVFWGNDGKDIAHHLGLI 5ybr A 2.26 BS03 8T9 A 1 N67 R72 M116 Q127 H130 D132 N152 S232 M241 N68 R73 M117 Q128 H131 D133 N153 S233 M242 29317628 LVPGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECLINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAIMQPGDCYLMSGKVIHGAGHNATTTDRRRALALSIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSVQHCVDMVHFWGNDGKDIAHHLGLI 5ybr B 2.26 BS02 AKG B 1 R72 Q127 H130 F154 T167 H214 A216 R226 R73 Q128 H131 F155 T168 H214 A216 R226 29317628 LVPRGSHMPPRLQRFPATASDEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNGNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECLINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAMQPGDCYLMSGKVIHGAGHNATTTDRRRALALSIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSHFWGNDGKDIAHHLGLIS 5ybs A 2.30 BS03 8TC B 1 C273 D276 V278 C274 D276 V278 29317628 LVPGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNGSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECLINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAIMQPGDCYLMSGKVIHGAGHNATTTDRRRALALSIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSVQHCVDMVHFWGNDGKDIAHHLGLI 5ybs B 2.30 BS03 8TC B 1 S66 N67 R72 M116 Q127 H130 D132 N152 A230 S232 M241 S68 N69 R74 M118 Q129 H132 D134 N154 A230 S232 M241 29317628 GLVPRGSHMPPRLQRFTASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNNGNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECLINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAMQPGDCYLMSGKVIHGAGHNTTTDRRRALALSIIRRELRPMQAFSLSVPMKLAREMSERSQTMFGFRSSHFWGNDGKDIAHHLGLI 5ybt B 2.35 BS04 8TC B 1 S66 N67 R72 M116 Q127 H130 D132 N152 S232 S67 N68 R73 M117 Q128 H131 D133 N153 S233 29317628 VPRGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFISPEQVARFSQEVDPAMEKIPVEVTNGNSNDRTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECLINFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAIMQPGDCYLMSGKVIHGAGHNATTTDRRRALALSIIRRELRPVQAFSLSVPMKLAREMSERSQTMFGFRSSVQHCDMVHFWGNDGKDIAHHLGLIS 5yc3 A 2.60 BS01 III P 1 T5 D14 G15 A16 D17 E18 F19 W20 I21 C22 W29 I45 K46 T10 D19 G20 A21 D22 E23 F24 W25 I26 C27 W34 I50 K51 GPLGSDHGETLCGACGDSDGADEFWICCDLCEKWFHGKCVKITPARAEHIKQYKCPSCSN 5yc3 A 2.60 BS02 ZN A 1 C7 C10 H31 C34 C12 C15 H36 C39 GPLGSDHGETLCGACGDSDGADEFWICCDLCEKWFHGKCVKITPARAEHIKQYKCPSCSN 5yc3 A 2.60 BS03 ZN A 2 C23 C26 C50 C53 C28 C31 C55 C58 GPLGSDHGETLCGACGDSDGADEFWICCDLCEKWFHGKCVKITPARAEHIKQYKCPSCSN 5yc4 A 2.70 BS01 III P 1 G15 A16 D17 E18 F19 W20 I21 C22 W29 I45 K46 G20 A21 D22 E23 F24 W25 I26 C27 W34 I50 K51 GPLGSDHGETLCGACGDSDGADEFWICCDLCEKWFHGKCVKITPARAEHIKQYKCPSCSN 5yt4 A 2.00 BS01 GOL A 1 Q55 N65 W72 Q75 Q54 N64 W71 Q74 29293962 SLLPVPYTEAASLSTGSTVTIKGRPLACFLNEPYLQVDFHTEMKEESDIVFAFQVCFGRRVVMNSREYGAWKQQVESKNMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHRIKPEAVKMVQVWRDISLTKFNVSY 6asa A 2.55 BS01 GDP A 1 G13 G15 K16 S17 A18 N116 K117 D119 L120 S145 A146 K147 G13 G15 K16 S17 A18 N116 K117 D119 L120 S145 A146 K147 29235861 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYEPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKE 6b41 A 2.61 BS01 CJV A 1 S155 S178 E179 D180 H181 F238 C241 A242 Y276 M278 N282 Y319 M322 Y323 G326 C329 R330 W341 E363 V367 V371 S151 S174 E175 D176 H177 F234 C237 A238 Y272 M274 N278 Y315 M318 Y319 G322 C325 R326 W337 E359 V363 V367 29284071 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEASALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSGTVAGTARGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTA 6b41 A 2.61 BS02 7PR A 1 F365 E366 N369 D370 F361 E362 N365 D366 29284071 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEASALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSGTVAGTARGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTA 6b41 A 2.61 BS03 7PR A 2 W126 L129 R131 Y133 W198 W122 L125 R127 Y129 W194 29284071 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEASALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSGTVAGTARGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTA 6b41 A 2.61 BS04 7PR A 3 L249 L289 L245 L285 29284071 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEASALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSGTVAGTARGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTA 6b58 A 2.61 BS01 FAD A 1 G11 A12 G13 G14 A15 S36 K37 V38 S43 H44 T45 A48 E49 H155 V157 A191 T192 G193 T203 N204 D211 H355 Y356 G378 E379 R390 S393 S395 L396 L399 G12 A13 G14 G15 A16 S37 K38 V39 S44 H45 T46 A49 E50 H122 V124 A158 T159 G160 T170 N171 D178 H322 Y323 G345 E346 R357 S360 S362 L363 L366 1.3.5.4 MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWKTGFHMLHTLFQTSLQFPQIQRFDEHFVLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPA 6bld A 2.00 BS01 HEM A 1 F102 L103 H110 R114 F121 L257 A260 G261 T264 T265 V302 P307 V308 F311 R313 G363 F364 G365 H370 C372 L373 G374 L377 A378 Q381 F97 L98 H105 R109 F116 L252 A255 G256 T259 T260 V297 P302 V303 F306 R308 G358 F359 G360 H365 C367 L368 G369 L372 A373 Q376 ASVRPYDTIDLSSRAFWASSASQRESSFSELRAERPVSWHPPVEDALIQDPNDPGFWAVTRRADIVAVSRTNEVFLSGNGVLFENVPAELLEASQSFLAMDPPRHTKLRKLVSAAFTPRQVRRIEDSIKINAKGIVDELRMAGGGVDFVEHCAKELPIRTLSDMVGIPEADRERVAHAADALVSWADPRYLNGREPLAVLFENQMYLHQVAASLAAERRDRPGDDLFSALVNAEVDGDRLADADVAAFFVLLAVAGNDTTRQTISHGLKALTDFPSQKAWLLADFDTRIGTAVEELVRWATPVMTFRRTAAADFELGGQLIRAGEKVVMFYASGNWDEDAFCHPERLDLSRSPNPHVGFGGGGVHFCLGAHLARAQLRAIFGELLVQLPDIQAGDPVYVPGNFVHAIRSMPCTF 6bld A 2.00 BS02 DXJ A 1 S99 Q100 L103 L187 L205 Q209 V259 A260 F311 S94 Q95 L98 L182 L200 Q204 V254 A255 F306 ASVRPYDTIDLSSRAFWASSASQRESSFSELRAERPVSWHPPVEDALIQDPNDPGFWAVTRRADIVAVSRTNEVFLSGNGVLFENVPAELLEASQSFLAMDPPRHTKLRKLVSAAFTPRQVRRIEDSIKINAKGIVDELRMAGGGVDFVEHCAKELPIRTLSDMVGIPEADRERVAHAADALVSWADPRYLNGREPLAVLFENQMYLHQVAASLAAERRDRPGDDLFSALVNAEVDGDRLADADVAAFFVLLAVAGNDTTRQTISHGLKALTDFPSQKAWLLADFDTRIGTAVEELVRWATPVMTFRRTAAADFELGGQLIRAGEKVVMFYASGNWDEDAFCHPERLDLSRSPNPHVGFGGGGVHFCLGAHLARAQLRAIFGELLVQLPDIQAGDPVYVPGNFVHAIRSMPCTF 6bml A 2.95 BS01 ZN A 1 C142 C145 H155 C162 C138 C141 H151 C158 2.3.1.225 29326245 TLWRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRAKFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDGNGFSLGASKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRL 6bml B 2.95 BS03 PAP B 1 K135 H140 H141 S143 K130 H135 H136 S138 2.3.1.225 29326245 LWRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRAKFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDGNGFSLGASKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRLVGM 6bmm A 2.35 BS03 DYD A 1 L279 L280 L273 L274 2.3.1.225 29326245 WRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRAKFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDGNGFSLGCSKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRL 6bmm A 2.35 BS04 DYD A 2 Y277 F283 Y271 F277 2.3.1.225 29326245 WRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRAKFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDGNGFSLGCSKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRL 6bmm A 2.35 BS05 DYD A 3 W267 F271 W278 L279 W261 F265 W272 L273 2.3.1.225 29326245 WRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRAKFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDGNGFSLGCSKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRL 6bmm A 2.35 BS06 DYD A 4 E191 I194 E185 I188 2.3.1.225 29326245 WRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRAKFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDGNGFSLGCSKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRL 6bmm B 2.35 BS03 DYD B 1 M64 K275 K276 L279 L280 M57 K268 K269 L272 L273 2.3.1.225 29326245 RCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRAKFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDGNGFSLGCSKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRLV 6bs6 A 2.17 BS01 GLC A 1 Y260 L290 W299 K304 Y218 L248 W257 K262 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS02 GLC A 2 Y260 W287 N330 Y218 W245 N288 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS03 GLC A 3 K391 L433 K349 L391 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS04 GLC A 4 F345 A389 K391 H392 E431 F303 A347 K349 H350 E389 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS05 GLC A 5 Y114 H154 F345 F350 R386 D388 E431 H497 N498 Y72 H112 F303 F308 R344 D346 E389 H455 N456 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS06 GLC A 6 H112 Y114 F350 D545 R549 H70 Y72 F308 D503 R507 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS07 GLC A 7 S110 H112 D115 T347 W349 F350 S68 H70 D73 T305 W307 F308 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS08 GLC A 8 E435 D437 E393 D395 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS09 GLC A 9 R457 W460 R415 W418 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS10 GLC A 10 R457 W460 Y469 D473 R415 W418 Y427 D431 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 A 2.17 BS11 GLC A 11 Y469 K472 Y427 K430 3.2.1.1 QWTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSYTLKLGGYASVVFKLGN 6bs6 B 2.17 BS02 GLC B 2 Y260 G262 W287 N330 Y217 G219 W244 N287 3.2.1.1 WTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSDSYTLKLGGYASVVFKLGN 6bs6 B 2.17 BS03 GLC B 3 E263 W287 E220 W244 3.2.1.1 WTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSDSYTLKLGGYASVVFKLGN 6bs6 B 2.17 BS05 GLC B 5 F345 A389 K391 H392 E431 L433 F302 A346 K348 H349 E388 L390 3.2.1.1 WTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSDSYTLKLGGYASVVFKLGN 6bs6 B 2.17 BS07 GLC B 7 H112 Y114 D545 R549 H69 Y71 D502 R506 3.2.1.1 WTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSDSYTLKLGGYASVVFKLGN 6bs6 B 2.17 BS10 GLC B 10 W460 Y469 D473 W417 Y426 D430 3.2.1.1 WTALTASPDTWDETKRADISYQLLLYSFADSDGDGYGDLNGVTQKLDYLNQLGVKALWLSPIHPCMSYHGYDVTDYTKVNPQLGTESDFDRLVTEAHNRGIKIYLDYVMNHTGTAHPWFTEASSSSESPYRNYYSFSEDPKTDIAAGKIAMITQEGAAGYNAAEWFQVSDETAAVKGLLKFTLDWSNAPSPILVVSTGTKADEDNPDTGTDNAKYLYYGEDICKKFYDKGNNIYELTVDFESTWGLLIRTSNASFWPSGTKYGASSSSEKLALNKDFKLTNAGNPANIMFDSQQITYFHSHFCTDWFADLNYGPVDQAGESPAYQAIADAAKGWIARGVDGLRLDAVKHIYHSETSEENPRFLKMFYEDMNAYYKQKGHTDDFYMIGEVLSEYDKVAPYYKGLPALFEFSFWYRLEWGINNSTGCYFAKDILSYQQKYANYRSDYIEATKLSNHNEDRTSSKLGKSADKCKLAAAVLLTSAGHPYIYYGEELGLYGTKDNGDEYVRSPMLWGDSYTTNYTDKTDATVSKNVKTVADQQADTHSLLNIYFSLTRLRNTYPALAEGNMTKHSVYNESQEKDYKPIAAWYMTKDNEKLLVIHNFGGTAMQLPLTDKIEKVLFVNGETQQNTDSDSYTLKLGGYASVVFKLGN 6by0 A 2.93 BS01 HEM A 1 R125 V127 H128 R165 G184 V199 G200 N201 F206 F214 I274 H275 F391 L407 R411 S414 Y415 T418 Q419 R422 R98 V100 H101 R138 G157 V172 G173 N174 F179 F187 I247 H248 F364 L380 R384 S387 Y388 T391 Q392 R395 1.11.1.6 SLAPEDGSHRPAAEPTPPGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIELTDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALKAKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDANYYLMEAYKHLKPIALAGDARKFKATIKIADQGEEGIVEADSADGSFMDELLTLMAAHRVWSRIPKIDKIPA 6by0 C 2.93 BS01 HEM C 1 R125 V127 H128 R165 G184 V199 G200 N201 F206 F214 I274 F391 L407 G410 R411 S414 Y415 T418 Q419 R422 R98 V100 H101 R138 G157 V172 G173 N174 F179 F187 I247 F364 L380 G383 R384 S387 Y388 T391 Q392 R395 1.11.1.6 SLAPEDGSHRPAAEPTPPGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIELTDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALKAKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDANYYLMEAYKHLKPIALAGDARKFKATIKIEEGIVEADSADGSFMDELLTLMAAHRVWSRIPKIDKIPA 6c23 A 3.90 BS01 III E 1 F429 F432 E443 A444 D446 P451 W452 F4 F7 E18 A19 D21 P26 W27 LRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESED 6c23 K 3.90 BS01 III O 1 Q648 A651 D652 G655 L666 F667 N668 A697 K698 F724 Y726 R727 Y728 Q238 A241 D242 G245 L256 F257 N258 A287 K288 F314 Y316 R317 Y318 2.1.1.43 ECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIISNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALK 6c23 L 3.90 BS01 III B 1 F97 N307 Y308 C324 I363 W364 Y365 R414 D430 F18 N228 Y229 C245 I284 W285 Y286 R335 D351 YSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR 6c23 P 3.90 BS01 III E 1 N255 E256 N24 E25 EDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKLPKDTALLLDPNIYRTMPQKRLKR 6c23 Q 3.90 BS01 III E 1 L87 Q95 R98 L7 Q15 R18 ADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKG 6c24 A 3.50 BS01 III E 1 F429 Y430 F432 Q441 T442 E443 A444 D446 P451 W452 F4 Y5 F7 Q16 T17 E18 A19 D21 P26 W27 LRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESED 6c24 K 3.50 BS01 III O 1 Q648 D652 G655 L666 F667 N668 A697 F724 Y726 R727 Y728 Q238 D242 G245 L256 F257 N258 A287 F314 Y316 R317 Y318 2.1.1.43 ECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIISNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALK 6c24 L 3.50 BS01 III B 1 F97 Y148 N307 I363 W364 R414 F18 Y69 N228 I284 W285 R335 YSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR 6c3p A 5.60 BS01 ATP A 1 K39 I182 F183 S184 K185 L205 Y330 S331 F333 G334 N335 K8 I151 F152 S153 K154 L174 Y299 S300 F302 G303 N304 29286281 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTIKVPTPLCTARQLDEDHSLLEAL 6c3p A 5.60 BS02 ATP A 2 N48 I49 R50 E51 N17 I18 R19 E20 29286281 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTIKVPTPLCTARQLDEDHSLLEAL 6c3p B 5.60 BS01 ATP A 1 I49 R50 I18 R19 29286281 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTIKVPTPLCTARQLDEDHSLLEAL 6c3p C 5.60 BS02 ATP C 1 I49 R50 E51 I18 R19 E20 29286281 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTIKVPTPLCTARQLDEDHSLLEAL 6c3p E 5.60 BS01 ADP E 1 Y1353 V1360 T1380 G1381 S1382 G1383 K1384 S1385 S1386 Y1131 V1138 T1158 G1159 S1160 G1161 K1162 S1163 S1164 29286281 PLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIRCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK 6c3p E 5.60 BS02 MG E 1 S720 Q774 S608 Q637 29286281 PLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIRCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK 6c3p E 5.60 BS03 ATP E 1 S408 M409 W688 V715 G716 C717 G718 K719 S720 S721 Q774 E1479 N1480 F1481 S1482 S361 M362 W576 V603 G604 C605 G606 K607 S608 S609 Q637 E1257 N1258 F1259 S1260 29286281 PLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIRCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK 6c49 A 1.85 BS01 ZN A 1 C96 C99 C102 C110 C94 C97 C100 C108 1.1.1.1 NNTIQAYAAMQAGEKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAGHEIIGRIVALGSEAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENIATIVGHAGGFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVFDPLLKHKIQATHHVGVIGIGGLGHIAIKLLKAWGCEITAFSSNPDKTEELKAMGADHVVNSRDTEAVKAQKGKFDLLLSTVNVNWRAFISTLAPNGSLHFLGLTLEPVPVSVGSLIDGAKSVTGSPTGSPAALRQLLKFAARKKIAPQIELFPMSQLNEAIERLHSGQARYRIVLKADFAE 6c49 A 1.85 BS02 ZN A 2 C43 H65 E66 C153 C41 H63 E64 C151 1.1.1.1 NNTIQAYAAMQAGEKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAGHEIIGRIVALGSEAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENIATIVGHAGGFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVFDPLLKHKIQATHHVGVIGIGGLGHIAIKLLKAWGCEITAFSSNPDKTEELKAMGADHVVNSRDTEAVKAQKGKFDLLLSTVNVNWRAFISTLAPNGSLHFLGLTLEPVPVSVGSLIDGAKSVTGSPTGSPAALRQLLKFAARKKIAPQIELFPMSQLNEAIERLHSGQARYRIVLKADFAE 6c5c A 1.85 BS01 NAD A 1 D42 N44 M45 P78 E80 K83 G111 G112 V113 D116 T136 T137 D143 S144 K149 N159 F176 T179 L180 Q184 D45 N47 M48 P81 E83 K86 G114 G115 V116 D119 T139 T140 D146 S147 K152 N162 F179 T182 L183 Q187 4.2.3.4 SNAMSIEKVPILGKETIHVGYGIADHIVREVIANLASSTYVIVTDTNMARTPQYSKLTDDFKTNLSEKRPESRLLTYCVSPGENNKNRATKAAVEDFLLQQGCTRDTVILAVGGGVIGDMIGFVAATFMRGVRVVQVPTTLLAMVDSSVGGKTAIDTPLGKNFIGAFHQPEYVFCDVSFLETLPARQFINGMAEVVKTAAIWNEEEFTRLENFSKKFLSVVTSKKPDLQSIKAELVKTVLESVRVKAGVVSSDEAGLRNLLNFGHTIGHAIEAVLTPEALHGECVSIGMIKEAELSRYLGILPPVAVARLSKCLVAYGLPVSIDDKEFLKKVGPKRHYVEIDILLKKMAIDKKNDIRCVLLEKIGKCYQLKAHQVSKQDLSFVLT 6eu6 A 1.98 BS01 ZDM A 1 I183 P187 L314 K315 I316 I183 P187 L314 K315 I316 29323112 MENIQININHLWVIMAACMVFLMQLGFTSYETGFSQSKNAISIALRNLVDTLISSLVFFSVGFGFMFGKSYMGLIGIDLFFANDLALHPNTLSYSFFFFQMVFASTAATILTGAIAERSGFIPNIAGTAFIVAIIYPIFGHWAWGNLFSPDQTGWLKELGFIDFAGATVVHSIGGWFAMAAAIMVGPRIDKYNPDGSSNRIGLHNVPLATLGTFFLWFGWFGFNGGSLLRVSVNIGLVILNTNMAAASAGVSALIFIYATRKRIEAGSLFTAILAGLVAITASSNMVTPVSAVAIGLITGILAIIAEGFIEKTLKIDDPVSAIAVHGVGGVIGTLCVAIFAQKSYLLAENGSRMHQLGIQALGVIVAFSWSFGLGMLFFLCLKKVKRLRVTPEEEKRGLNVAEAA 6eu6 A 1.98 BS02 NH4 A 1 Q24 N47 D50 T51 T109 Q24 N47 D50 T51 T109 29323112 MENIQININHLWVIMAACMVFLMQLGFTSYETGFSQSKNAISIALRNLVDTLISSLVFFSVGFGFMFGKSYMGLIGIDLFFANDLALHPNTLSYSFFFFQMVFASTAATILTGAIAERSGFIPNIAGTAFIVAIIYPIFGHWAWGNLFSPDQTGWLKELGFIDFAGATVVHSIGGWFAMAAAIMVGPRIDKYNPDGSSNRIGLHNVPLATLGTFFLWFGWFGFNGGSLLRVSVNIGLVILNTNMAAASAGVSALIFIYATRKRIEAGSLFTAILAGLVAITASSNMVTPVSAVAIGLITGILAIIAEGFIEKTLKIDDPVSAIAVHGVGGVIGTLCVAIFAQKSYLLAENGSRMHQLGIQALGVIVAFSWSFGLGMLFFLCLKKVKRLRVTPEEEKRGLNVAEAA 6eu6 A 1.98 BS03 NH4 A 2 E31 N47 T109 T112 E31 N47 T109 T112 29323112 MENIQININHLWVIMAACMVFLMQLGFTSYETGFSQSKNAISIALRNLVDTLISSLVFFSVGFGFMFGKSYMGLIGIDLFFANDLALHPNTLSYSFFFFQMVFASTAATILTGAIAERSGFIPNIAGTAFIVAIIYPIFGHWAWGNLFSPDQTGWLKELGFIDFAGATVVHSIGGWFAMAAAIMVGPRIDKYNPDGSSNRIGLHNVPLATLGTFFLWFGWFGFNGGSLLRVSVNIGLVILNTNMAAASAGVSALIFIYATRKRIEAGSLFTAILAGLVAITASSNMVTPVSAVAIGLITGILAIIAEGFIEKTLKIDDPVSAIAVHGVGGVIGTLCVAIFAQKSYLLAENGSRMHQLGIQALGVIVAFSWSFGLGMLFFLCLKKVKRLRVTPEEEKRGLNVAEAA 6ewz A 2.24 BS01 GTP A 1 K88 K92 D107 K138 K140 Y142 K147 N149 Y151 H155 E174 Q176 A186 E189 H190 R193 K60 K64 D79 K110 K112 Y114 K119 N121 Y123 H127 E146 Q148 A158 E161 H162 R165 2.7.6.5 29326162 DEAFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE 6ewz A 2.24 BS02 APC A 1 E76 R78 K80 S84 K88 R91 D107 G110 I111 R112 E174 Q176 E48 R50 K52 S56 K60 R63 D79 G82 I83 R84 E146 Q148 2.7.6.5 29326162 DEAFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE 6ewz A 2.24 BS03 MG A 1 K80 K88 D107 K52 K60 D79 2.7.6.5 29326162 DEAFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE 6ewz B 2.24 BS01 GTP B 1 K88 K92 K138 Y142 K147 N149 Y151 H155 E174 Q176 A186 E189 H190 K58 K62 K108 Y112 K117 N119 Y121 H125 E144 Q146 A156 E159 H160 2.7.6.5 29326162 AFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE 6ewz B 2.24 BS02 APC B 1 E76 R78 K80 S84 K88 R91 D107 G110 I111 R112 E174 I175 Q176 H190 E46 R48 K50 S54 K58 R61 D77 G80 I81 R82 E144 I145 Q146 H160 2.7.6.5 29326162 AFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE 6ex0 A 2.78 BS01 C1Z A 1 D107 R112 K147 N149 Y151 H155 Q176 A186 E189 H190 R193 D77 R82 K117 N119 Y121 H125 Q146 A156 E159 H160 R163 2.7.6.5 29326162 AFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYEKYRDLLKECATEITEVEDKLQQIHSEITE 6ex0 B 2.78 BS01 C1Z B 1 R78 K80 K88 R91 D107 R112 K147 N149 Y151 H155 Q176 A186 E189 H190 R193 R47 K49 K57 R60 D76 R81 K116 N118 Y120 H124 Q145 A155 E158 H159 R162 2.7.6.5 29326162 FDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYNAETEKYRDLLKECATEITEVEDKLQQIHSEITE 6f39 A 5.80 BS01 CA A 1 Y21 D57 T101 D102 S104 N105 Y17 D51 T92 D93 S95 N96 3.4.21.41 29311313 PQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFFDLEPSEGCFYDYVKISKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIYKGFLAYYQDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEI 6f39 A 5.80 BS02 CA A 2 D125 L126 D127 Y151 G154 Y155 D112 L113 D114 Y138 G141 Y142 3.4.21.41 29311313 PQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFFDLEPSEGCFYDYVKISKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIYKGFLAYYQDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEI 6f39 A 5.80 BS03 CA A 3 Y197 D226 D273 S275 G276 D277 S278 Y183 D212 D259 S261 G262 D263 S264 3.4.21.41 29311313 PQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFFDLEPSEGCFYDYVKISKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIYKGFLAYYQDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEI 6f39 B 5.80 BS01 CA B 1 Y21 N23 D57 T101 D102 S104 N105 Y17 N19 D51 T95 D96 S98 N99 3.4.21.41 29311313 PQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 6f39 B 5.80 BS02 CA B 2 L126 D127 E128 Y151 G154 Y155 L119 D120 E121 Y144 G147 Y148 3.4.21.41 29311313 PQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 6f39 B 5.80 BS03 CA B 3 Y197 D226 Y235 D236 D273 S275 Y189 D218 Y227 D228 D265 S267 3.4.21.41 29311313 PQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 6fah A 3.13 BS01 FAD A 1 G283 M284 G285 S309 R310 A311 V324 G325 Q326 T327 G328 G340 I341 S342 A344 Q346 H347 N361 K362 G378 D379 L380 G276 M277 G278 S302 R303 A304 V317 G318 Q319 T320 G321 G333 I334 S335 A337 Q339 H340 N354 K355 G371 D372 L373 1.3.1.108 29325219 EKCIGCSKCQKSCPFDAITIENKIAVIGDACTNCGTCIDVCPTEAILQEGTEKIVRDLSMYKGVWVFAEQREGKIMPVVFELLGEGKKLANEIGTELCAILCGSNVAELTDELFAYGADKVYLADAPELEKYTTDGYSKIINEAIGLYKPEIVLYGATHIGRDLAPCLAVKVNTGLTADCTKLEIDPDDKKIRQTRPAFGGNLMATIVCPGSRPQMSTVRPGVMDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDADFIVSGGMGLGKPEGFELLKQLADKLGGTVATSRACVDAGWADHAQQVGQTGTTVKPQIYFACGISGAIQHIAGMQDSDIIIAINKNENAPIFEVADYGIVGDLYKVIPAIIEELDKIGK 6fah A 3.13 BS02 SF4 A 1 C10 G12 C13 S14 C16 A32 C48 A52 C3 G5 C6 S7 C9 A25 C41 A45 1.3.1.108 29325219 EKCIGCSKCQKSCPFDAITIENKIAVIGDACTNCGTCIDVCPTEAILQEGTEKIVRDLSMYKGVWVFAEQREGKIMPVVFELLGEGKKLANEIGTELCAILCGSNVAELTDELFAYGADKVYLADAPELEKYTTDGYSKIINEAIGLYKPEIVLYGATHIGRDLAPCLAVKVNTGLTADCTKLEIDPDDKKIRQTRPAFGGNLMATIVCPGSRPQMSTVRPGVMDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDADFIVSGGMGLGKPEGFELLKQLADKLGGTVATSRACVDAGWADHAQQVGQTGTTVKPQIYFACGISGAIQHIAGMQDSDIIIAINKNENAPIFEVADYGIVGDLYKVIPAIIEELDKIGK 6fah A 3.13 BS03 SF4 A 2 C20 P21 A37 C38 T39 N40 C41 C44 C13 P14 A30 C31 T32 N33 C34 C37 1.3.1.108 29325219 EKCIGCSKCQKSCPFDAITIENKIAVIGDACTNCGTCIDVCPTEAILQEGTEKIVRDLSMYKGVWVFAEQREGKIMPVVFELLGEGKKLANEIGTELCAILCGSNVAELTDELFAYGADKVYLADAPELEKYTTDGYSKIINEAIGLYKPEIVLYGATHIGRDLAPCLAVKVNTGLTADCTKLEIDPDDKKIRQTRPAFGGNLMATIVCPGSRPQMSTVRPGVMDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDADFIVSGGMGLGKPEGFELLKQLADKLGGTVATSRACVDAGWADHAQQVGQTGTTVKPQIYFACGISGAIQHIAGMQDSDIIIAINKNENAPIFEVADYGIVGDLYKVIPAIIEELDKIGK 6fah A 3.13 BS04 FAD B 1 L183 T184 R203 A205 F206 I214 L176 T177 R196 A198 F199 I207 1.3.1.108 29325219 EKCIGCSKCQKSCPFDAITIENKIAVIGDACTNCGTCIDVCPTEAILQEGTEKIVRDLSMYKGVWVFAEQREGKIMPVVFELLGEGKKLANEIGTELCAILCGSNVAELTDELFAYGADKVYLADAPELEKYTTDGYSKIINEAIGLYKPEIVLYGATHIGRDLAPCLAVKVNTGLTADCTKLEIDPDDKKIRQTRPAFGGNLMATIVCPGSRPQMSTVRPGVMDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDADFIVSGGMGLGKPEGFELLKQLADKLGGTVATSRACVDAGWADHAQQVGQTGTTVKPQIYFACGISGAIQHIAGMQDSDIIIAINKNENAPIFEVADYGIVGDLYKVIPAIIEELDKIGK 6fah B 3.13 BS01 FAD B 1 C6 A7 K8 D38 T61 M62 A93 D94 T95 T98 L102 G118 Q120 A121 G124 T126 A127 Q128 V129 T223 V225 C6 A7 K8 D38 T61 M62 A93 D94 T95 T98 L102 G118 Q120 A121 G124 T126 A127 Q128 V129 T223 V225 1.3.1.108 29325219 MRILVCAKQVPDTNEVKIDPKTGTMIREGVPSILNPDDANALEAALVIKDENPGTEVIVMTMGPPQASEMLRECLAMGADEAYLLSDRAFGGADTWATSATLAAGIKKVKKVDLVLAGRQAIDGDTAQVGSQIAQRLKMPVVTYVEDIKIEDKKAIVHRQMEDGYEVIEVQLPCLLTCVKELNDPRYMSVGGIMDAYEQPITIWNHEDIGLSPEACGLNASPTQVFRSFSPPAKGGGEMITGTTVNEVAGSLVSKLKEKHII 6fah C 3.13 BS01 FAD A 1 Y340 Y346 Y340 Y346 1.3.1.108 29325219 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVISGMLLKK 6fah C 3.13 BS02 FAD C 1 F122 L124 T125 G130 S131 F155 T157 V357 T364 Q366 M370 F122 L124 T125 G130 S131 F155 T157 V357 T364 Q366 M370 1.3.1.108 29325219 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVISGMLLKK 6fah C 3.13 BS03 FAD D 1 R267 Q269 F270 I274 F277 I280 Q335 I336 G339 R267 Q269 F270 I274 F277 I280 Q335 I336 G339 1.3.1.108 29325219 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVISGMLLKK 6fah C 3.13 BS04 FAD E 1 R152 E198 R152 E198 1.3.1.108 29325219 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVISGMLLKK 6fah D 3.13 BS01 FAD A 1 P127 R152 E198 P127 R152 E198 1.3.1.108 29325219 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVISGMLLKK 6fah D 3.13 BS02 FAD C 1 R267 Q269 F270 I274 F277 Q335 I336 G338 G339 R267 Q269 F270 I274 F277 Q335 I336 G338 G339 1.3.1.108 29325219 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVISGMLLKK 6fah D 3.13 BS03 FAD D 1 F122 L124 T125 G130 F155 T157 V357 Y361 E362 T364 Q366 F122 L124 T125 G130 F155 T157 V357 Y361 E362 T364 Q366 1.3.1.108 29325219 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVISGMLLKK 6fah E 3.13 BS01 FAD E 1 M284 G285 S309 R310 A311 Q323 V324 G325 Q326 T327 G328 G340 I341 S342 G343 Q346 H347 N361 K362 D379 L380 M281 G282 S306 R307 A308 Q320 V321 G322 Q323 T324 G325 G337 I338 S339 G340 Q343 H344 N358 K359 D376 L377 1.3.1.108 29325219 KVIEEKCIGCSKCQKSCPFDAITIENKIAVIGDACTNCGTCIDVCPTEAILQEGTEKIVRDLSMYKGVWVFAEQREGKIMPVVFELLGEGKKLANEIGTELCAILCGSNVAELTDELFAYGADKVYLADAPELEKYTTDGYSKIINEAIGLYKPEIVLYGATHIGRDLAPCLAVKVNTGLTADCTKLEIDPDDKKIRQTRPAFGGNLMATIVCPGSRPQMSTVRPGVMDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDADFIVSGGMGLGKPEGFELLKQLADKLGGTVATSRACVDAGWADHAQQVGQTGTTVKPQIYFACGISGAIQHIAGMQDSDIIIAINKNENAPIFEVADYGIVGDLYKVIPAIIEELDKIGK 6fah E 3.13 BS02 SF4 E 1 C10 C13 C16 C48 A52 I53 C7 C10 C13 C45 A49 I50 1.3.1.108 29325219 KVIEEKCIGCSKCQKSCPFDAITIENKIAVIGDACTNCGTCIDVCPTEAILQEGTEKIVRDLSMYKGVWVFAEQREGKIMPVVFELLGEGKKLANEIGTELCAILCGSNVAELTDELFAYGADKVYLADAPELEKYTTDGYSKIINEAIGLYKPEIVLYGATHIGRDLAPCLAVKVNTGLTADCTKLEIDPDDKKIRQTRPAFGGNLMATIVCPGSRPQMSTVRPGVMDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDADFIVSGGMGLGKPEGFELLKQLADKLGGTVATSRACVDAGWADHAQQVGQTGTTVKPQIYFACGISGAIQHIAGMQDSDIIIAINKNENAPIFEVADYGIVGDLYKVIPAIIEELDKIGK 6fah E 3.13 BS03 SF4 E 2 C20 P21 C38 T39 N40 C41 C44 C17 P18 C35 T36 N37 C38 C41 1.3.1.108 29325219 KVIEEKCIGCSKCQKSCPFDAITIENKIAVIGDACTNCGTCIDVCPTEAILQEGTEKIVRDLSMYKGVWVFAEQREGKIMPVVFELLGEGKKLANEIGTELCAILCGSNVAELTDELFAYGADKVYLADAPELEKYTTDGYSKIINEAIGLYKPEIVLYGATHIGRDLAPCLAVKVNTGLTADCTKLEIDPDDKKIRQTRPAFGGNLMATIVCPGSRPQMSTVRPGVMDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDADFIVSGGMGLGKPEGFELLKQLADKLGGTVATSRACVDAGWADHAQQVGQTGTTVKPQIYFACGISGAIQHIAGMQDSDIIIAINKNENAPIFEVADYGIVGDLYKVIPAIIEELDKIGK 6fah E 3.13 BS04 FAD F 1 L183 R203 I214 L180 R200 I211 1.3.1.108 29325219 KVIEEKCIGCSKCQKSCPFDAITIENKIAVIGDACTNCGTCIDVCPTEAILQEGTEKIVRDLSMYKGVWVFAEQREGKIMPVVFELLGEGKKLANEIGTELCAILCGSNVAELTDELFAYGADKVYLADAPELEKYTTDGYSKIINEAIGLYKPEIVLYGATHIGRDLAPCLAVKVNTGLTADCTKLEIDPDDKKIRQTRPAFGGNLMATIVCPGSRPQMSTVRPGVMDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDADFIVSGGMGLGKPEGFELLKQLADKLGGTVATSRACVDAGWADHAQQVGQTGTTVKPQIYFACGISGAIQHIAGMQDSDIIIAINKNENAPIFEVADYGIVGDLYKVIPAIIEELDKIGK 6fbk A 1.74 BS01 III P 1 G494 A495 I496 E497 F498 T499 E505 V510 E513 M514 E516 S517 F519 G33 A34 I35 E36 F37 T38 E44 V49 E52 M53 E55 S56 F58 2.7.11.1 EDTGVRVELAEEDHGRKSTIALRLWVEDPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRE 6ffl A 1.71 BS01 GLC A 1 E43 P65 D67 E163 P164 F165 M341 R348 W351 R355 E41 P63 D65 E161 P162 F163 M339 R346 W349 R353 VRIQIWHQMIYGHRQVLAEALEKFEKENPGITVQATYRETEELRSSFQSAAMGGSGPELVYGPSDQVGPFATMGIVRPLDEVLGSDYFQNFDPLAAPVYDGKHYMIGDAVGNHLMLLYNKKFITTPPKNSQELIELGKKMTVDTNGDGKIDRWGLVFNYTEPFFFAPFIPAFGEAFLKADGVTPNLNTTALKDTFQFILKLRDQDKIIPKECDYETANALFKENKAAMLINGDWSWGDYQQAKVDFGIARIPMISETGKWPSPLVGTKGYSLNANMKSEAHYEAAVKLLKYLTSTPVQLLFAEKVGVLPSNLQARESDIVKNNPLLKISADIMEVGTPMPVTPEVRAVWDSLRIQYQKVLAGSLQPQAAAEQAQITAEQQIRD 6ffl A 1.71 BS02 GLC A 2 P65 N114 E163 F165 W236 K270 P63 N112 E161 F163 W234 K268 VRIQIWHQMIYGHRQVLAEALEKFEKENPGITVQATYRETEELRSSFQSAAMGGSGPELVYGPSDQVGPFATMGIVRPLDEVLGSDYFQNFDPLAAPVYDGKHYMIGDAVGNHLMLLYNKKFITTPPKNSQELIELGKKMTVDTNGDGKIDRWGLVFNYTEPFFFAPFIPAFGEAFLKADGVTPNLNTTALKDTFQFILKLRDQDKIIPKECDYETANALFKENKAAMLINGDWSWGDYQQAKVDFGIARIPMISETGKWPSPLVGTKGYSLNANMKSEAHYEAAVKLLKYLTSTPVQLLFAEKVGVLPSNLQARESDIVKNNPLLKISADIMEVGTPMPVTPEVRAVWDSLRIQYQKVLAGSLQPQAAAEQAQITAEQQIRD 6ffl A 1.71 BS03 GLC A 3 Q10 M11 I12 Y216 W236 K270 Q8 M9 I10 Y214 W234 K268 VRIQIWHQMIYGHRQVLAEALEKFEKENPGITVQATYRETEELRSSFQSAAMGGSGPELVYGPSDQVGPFATMGIVRPLDEVLGSDYFQNFDPLAAPVYDGKHYMIGDAVGNHLMLLYNKKFITTPPKNSQELIELGKKMTVDTNGDGKIDRWGLVFNYTEPFFFAPFIPAFGEAFLKADGVTPNLNTTALKDTFQFILKLRDQDKIIPKECDYETANALFKENKAAMLINGDWSWGDYQQAKVDFGIARIPMISETGKWPSPLVGTKGYSLNANMKSEAHYEAAVKLLKYLTSTPVQLLFAEKVGVLPSNLQARESDIVKNNPLLKISADIMEVGTPMPVTPEVRAVWDSLRIQYQKVLAGSLQPQAAAEQAQITAEQQIRD 6fg7 A 1.90 BS01 FUC A 1 F63 N66 F35 N38 ADEDDIRCLRGLKASLTDPQNALKSWNFDNTTLGFLCNFVGVSCWNNQENRVINLELRDMGLSGKIPDSLQYCASLQKLDLSSNRLSGNIPTELCNWLPFLVSLDLSNNELNGEIPPDLAKCSFVNSLVLSDNRLSGQIPVQFSALGRLGRFSVANNDLSGRIPVFFSSPSYSSDDFSGNKGLCGRPLSSSCG