4w2r A 2.81 BS01 ZN A 1 C420 H422 C427 C431 C253 H255 C260 C264 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r A 2.81 BS02 ZN A 2 C420 C433 C440 C444 C253 C266 C273 C277 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r A 2.81 BS03 ZN A 3 C427 C440 C446 C450 C260 C273 C279 C283 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r A 2.81 BS04 ZN A 4 C457 C459 C463 C468 C290 C292 C296 C301 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r A 2.81 BS05 ZN A 5 C463 C477 C485 C498 C296 C310 C318 C331 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r A 2.81 BS06 ZN A 6 C457 C470 C477 C482 C290 C303 C310 C315 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r A 2.81 BS07 ZN A 7 C274 C277 C282 H285 C183 C186 C191 H194 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r A 2.81 BS08 CJD A 1 I109 Y111 G520 W521 Y555 Y558 C560 F562 T575 R582 F583 A584 N585 I92 Y94 G353 W354 Y388 Y391 C393 F395 T408 R415 F416 A417 N418 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r B 2.81 BS01 ZN B 1 C427 C440 C446 C450 C262 C275 C281 C285 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r B 2.81 BS02 ZN B 2 C420 C433 C440 C444 C255 C268 C275 C279 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r B 2.81 BS03 ZN B 3 C420 H422 C427 C431 C255 H257 C262 C266 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r B 2.81 BS04 ZN B 4 C457 C470 C477 C482 C292 C305 C312 C317 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r B 2.81 BS05 ZN B 5 C463 C477 C485 C498 C298 C312 C320 C333 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r B 2.81 BS06 ZN B 6 C457 C459 C463 C468 C292 C294 C298 C303 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r B 2.81 BS07 ZN B 7 C274 C277 C282 H285 C186 C189 C194 H197 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 4w2r B 2.81 BS08 CJD B 1 I109 Y111 G520 W521 Y555 Y558 C560 F562 T575 R582 F583 A584 N585 I93 Y95 G355 W356 Y390 Y393 C395 F397 T410 R417 F418 A419 N420 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 5h62 A 1.66 BS01 MN A 1 D241 N338 S340 D202 N296 S298 SGHVSFAGIDYPLLPLNHQTPLVFQWFERNPDRFGQNEIPIINTQKNPYLNNIINAAIIEKERIIGIFVDGDFSKGQRKALGKLEQNYRNIKVIYNSDLNYSMYDKKLTTIYLENITKLEAQSASERDEVLLNGVKKSLEDVLKNNPEETLISSHNKDKGHLWFDFYRNLFLLKGSDAFLEAGKPGCHHLQPGGGCIYLDADMLLTDKLGTLYLPDGIAIHVSRHVSLENGIIAVNRSEHPALIKGLEIMHSKPYGDPYNDWLSKGLRHYFDGSHIQDYDAFCDFIEFKHENIIMNTSSLTASSWR 5h62 A 1.66 BS02 UDP A 1 Q64 W65 F66 Y88 F203 R207 Y237 D239 A240 D241 N338 S340 S345 S346 W347 R348 Q25 W26 F27 Y49 F164 R168 Y198 D200 A201 D202 N296 S298 S303 S304 W305 R306 SGHVSFAGIDYPLLPLNHQTPLVFQWFERNPDRFGQNEIPIINTQKNPYLNNIINAAIIEKERIIGIFVDGDFSKGQRKALGKLEQNYRNIKVIYNSDLNYSMYDKKLTTIYLENITKLEAQSASERDEVLLNGVKKSLEDVLKNNPEETLISSHNKDKGHLWFDFYRNLFLLKGSDAFLEAGKPGCHHLQPGGGCIYLDADMLLTDKLGTLYLPDGIAIHVSRHVSLENGIIAVNRSEHPALIKGLEIMHSKPYGDPYNDWLSKGLRHYFDGSHIQDYDAFCDFIEFKHENIIMNTSSLTASSWR 5h62 B 1.66 BS01 UDP B 1 Q64 W65 F66 Y88 H200 F203 Y237 D239 A240 D241 S340 Q24 W25 F26 Y48 H160 F163 Y197 D199 A200 D201 S300 GHVSFAGIDYPLLPLNHQTPLVFQWFERNPDRFGQNEIPIINTQKNPYLNNIINAAIIEKERIIGIFVDGDFSKGQRKALGKLEQNYRNIKVIYNSDLNYSMYDKKLTTIYLENITKLEAQSASERDEVLLNGVKKSLEDVLKNNPEETLISSHNKDKGHLWFDFYRNLFLLKGSDAFLEAGKPGCHHLQPGGGCIYLDADMLLTDKLGTLYLPDGIAIHVSRKDNHVSLENGIIAVNRSEHPALIKGLEIMHSKPYGDPYNDWLSKGLRHYFDGSHIQDYDAFCDFIEFKHENIIMNTSS 5h62 B 1.66 BS02 MN B 1 D241 N338 S340 D201 N298 S300 GHVSFAGIDYPLLPLNHQTPLVFQWFERNPDRFGQNEIPIINTQKNPYLNNIINAAIIEKERIIGIFVDGDFSKGQRKALGKLEQNYRNIKVIYNSDLNYSMYDKKLTTIYLENITKLEAQSASERDEVLLNGVKKSLEDVLKNNPEETLISSHNKDKGHLWFDFYRNLFLLKGSDAFLEAGKPGCHHLQPGGGCIYLDADMLLTDKLGTLYLPDGIAIHVSRKDNHVSLENGIIAVNRSEHPALIKGLEIMHSKPYGDPYNDWLSKGLRHYFDGSHIQDYDAFCDFIEFKHENIIMNTSS 5kvt A 2.45 BS01 YMX A 1 L516 G517 E518 V524 A542 F589 E590 M592 R593 G595 D596 R599 R654 N655 L657 G667 L16 G17 E18 V24 A38 F85 E86 M88 R89 G91 D92 R95 R150 N151 L153 G163 2.7.10.1 P04629 CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAHHHH 5mh1 A 1.10 BS01 BMA A 1 D22 K43 H52 E59 F126 A127 G128 D21 K42 H51 E58 F125 A126 G127 K1QRB6 29238341 AEWVSTTGNTIPDNAIRAGYDINKKALFIARAVVSGEMTPGKCGTHLEGAHIPFAGKEHIIQNYEVLVYPINALGFLDWQQASNGDVPGNAIDTASGIYIGRVLYSGSLIPCKIHTGFKVAYMGFAGKEHQSKEYEALYKVI 5mh1 A 1.10 BS02 MG A 1 P54 I111 P112 C113 M124 G125 P53 I110 P111 C112 M123 G124 K1QRB6 29238341 AEWVSTTGNTIPDNAIRAGYDINKKALFIARAVVSGEMTPGKCGTHLEGAHIPFAGKEHIIQNYEVLVYPINALGFLDWQQASNGDVPGNAIDTASGIYIGRVLYSGSLIPCKIHTGFKVAYMGFAGKEHQSKEYEALYKVI 5mh1 A 1.10 BS03 MG A 2 N91 Y140 K141 N90 Y139 K140 K1QRB6 29238341 AEWVSTTGNTIPDNAIRAGYDINKKALFIARAVVSGEMTPGKCGTHLEGAHIPFAGKEHIIQNYEVLVYPINALGFLDWQQASNGDVPGNAIDTASGIYIGRVLYSGSLIPCKIHTGFKVAYMGFAGKEHQSKEYEALYKVI 5n1r A 1.30 BS01 ZN A 1 H94 H96 H119 H92 H94 H117 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n1r A 1.30 BS02 8GH A 1 H94 H96 H119 V121 F131 G132 L198 T199 T200 P202 W209 H92 H94 H117 V119 F128 G129 L195 T196 T197 P199 W206 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n1s A 1.30 BS01 ZN A 1 H94 H96 H119 H92 H94 H117 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n1s A 1.30 BS02 8GE A 1 H94 H96 H119 F131 L198 T199 T200 P202 W209 H92 H94 H117 F128 L195 T196 T197 P199 W206 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n24 A 1.50 BS01 ZN A 1 H94 H96 H119 H92 H94 H117 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n24 A 1.50 BS02 8HE A 1 H94 H96 H119 F131 L198 T199 T200 W209 H92 H94 H117 F128 L195 T196 T197 W206 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n24 A 1.50 BS03 8HE A 2 H3 H4 W5 H10 N11 H15 W16 D19 H1 H2 W3 H8 N9 H13 W14 D17 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n25 A 1.40 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n25 A 1.40 BS02 8HK A 1 H94 H96 H119 F131 L198 T199 T200 W209 H91 H93 H116 F127 L194 T195 T196 W205 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n25 A 1.40 BS03 8HK A 2 H4 W5 H10 H15 W16 D19 F20 H1 W2 H7 H12 W13 D16 F17 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5n6o A 2.59 BS01 GDP A 1 A13 V14 G15 K16 T17 C18 F28 G30 I33 K116 D118 L119 S158 A159 L160 A12 V13 G14 K15 T16 C17 F27 G29 I32 K115 D117 L118 S157 A158 L159 P63000 29089502 QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 5n6o A 2.59 BS02 MG A 1 T17 D57 T16 D56 P63000 29089502 QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 5n6o B 2.59 BS01 GDP B 1 A13 V14 G15 K16 T17 C18 F28 I33 K116 D118 L119 A159 L160 A12 V13 G14 K15 T16 C17 F27 I32 K115 D117 L118 A158 L159 P63000 29089502 QAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 5n7q A 1.45 BS01 III I 1 D36 G38 S39 V78 Y79 G80 S81 Y196 D227 G229 T230 S231 L232 Q256 M307 D34 G36 S37 V76 Y77 G78 S79 Y194 D225 G227 T228 S229 L230 Q254 M305 V5HCK7 EGPYPEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCTTKYCLHHHRYDSSKSSTYEADGRNFTIVYGSGNVEGFISKDVCRIGSAKVSGQPLGEALVVGGESLLEAPFDGILGLAYPSIAVDGVVPVFDNMMKQGLLGEQNVFSVYLNRDPSSKEGGEVLFGGIDHDHYKGSITYVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIADTGTSLITGPPEEVDSLNQYLGGTKTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQTLCVSGFMGLEMPQPLWILGDVFLGPYYTIFDRDQDRVGFAEVA 5n7q B 1.45 BS01 III J 1 I34 D36 G38 S39 V78 Y79 G80 S81 S115 Y196 D227 G229 T230 S231 L232 Q256 L288 M303 M307 I32 D34 G36 S37 V76 Y77 G78 S79 S113 Y194 D225 G227 T228 S229 L230 Q254 L286 M301 M305 V5HCK7 EGPYPEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCTTKYCLHHHRYDSSKSSTYEADGRNFTIVYGSGNVEGFISKDVCRIGSAKVSGQPLGEALVVGGESLLEAPFDGILGLAYPSIAVDGVVPVFDNMMKQGLLGEQNVFSVYLNRDPSSKEGGEVLFGGIDHDHYKGSITYVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIADTGTSLITGPPEEVDSLNQYLGGTKTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQTLCVSGFMGLEMPQPLWILGDVFLGPYYTIFDRDQDRVGFAEVA 5nnw A 1.54 BS01 MG A 1 D93 D104 E106 H159 D90 D101 E103 H156 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPSAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSPSTGIGHRHDWENVVVWLDNAASANIVALSASAHSGYKKSFPADKSYLDGITAKISYKSTWPLDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5nnw B 1.54 BS01 MG B 1 D93 D104 E106 H159 D89 D96 E98 H148 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSPGHRHDWENVVVWLDNAASANIVALSASAHSGYKKSFPADKSYLDGITAKISYKSTDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5nnw C 1.54 BS01 MG C 1 D93 D104 E106 H159 D89 D100 E102 H154 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSPSTGIGHRHDWENVVVWLDNAASANIVALSASAHGYKKSFPADKSYLDGITAKISYKSTWPLDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5nnw D 1.54 BS01 MG D 1 E106 H159 E99 H152 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPSAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSIGHRHDWENVVVWLDNAASANIVALSASAHSGYKKSFPADKSYLDGITAKISYKSTWPLDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5nnw D 1.54 BS02 GCS D 1 D93 G100 H101 D158 D90 G93 H94 D151 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPSAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSIGHRHDWENVVVWLDNAASANIVALSASAHSGYKKSFPADKSYLDGITAKISYKSTWPLDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5no9 A 1.75 BS01 MG A 1 D93 D104 E106 H159 D89 D97 E99 H148 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSPSGHRHDWENVVVWLDNAASANIVALSASAHGYKKSFPADKSYLDGITAKISYKSTDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5no9 B 1.75 BS01 MG B 1 D93 D104 E106 H159 D92 D103 E105 H158 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPSGQAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSPSTGIGHRHDWENVVVWLDNAASANIVALSASAHSGYKKSFPADKSYLDGITAKISYKSTWPLDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5no9 C 1.75 BS01 MG C 1 D93 D104 E106 H159 D90 D101 E103 H154 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPSAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSPSTGIGHRHDWENVVVWLDNAASANIVALSASAGYKKSFPADKSYLDGITAKISYKSTWPLDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5no9 D 1.75 BS01 MG D 1 E106 H159 E160 E100 H153 E154 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPSAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSGIGHRHDWENVVVWLDNAASANIVALSASAHSGYKKSFPADKSYLDGITAKISYKSTWPLDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5no9 D 1.75 BS02 95Z D 1 D93 G100 H101 H128 D158 D90 G94 H95 H122 D152 Q9SPD4 29242345 AVINHDAVPVWPQPEPADATQALAVRFKPQLDVVNGCQPYPAVDPQGNTSGGLKPSAAACRDMSKAQVYSRSGTYNGYYAIMYSWYMPKDSGIGHRHDWENVVVWLDNAASANIVALSASAHSGYKKSFPADKSYLDGITAKISYKSTWPLDHELGFTTSAGKQQPLIQWEQMTQAARDALESTDFGNANVPFKSNFQDKLVKAFFQ 5oar B 2.30 BS01 NGT B 1 R193 H275 E307 D345 E346 W397 W419 Y445 D447 W482 W517 E519 R91 H173 E205 D243 E244 W295 W317 Y343 D345 W380 W415 E417 3.2.1.52 Q8J2T0 29239122 SNSLQYVNVQVKDIEADLQHGVDESYTLDVEEDSDTITINAETVWGALHAFTTLQQLVISDGHGGLIIEEPVNIKDSPLYPYRGIMLDTGRNFVSLPKIFEQLEGMSLSKLNVLHWHIDDAQSWPIWVDVYPEMVKDAYSPHEIYSRNDVRNIVNYARARGIRVIPEIDMPSHSSSGWKQVDPEMVTCTDSWWSNDDWPLHTAVEPNPGQLDIIYNKTYEVVGNVYKELSDIFPDHWFHVGGDEIQPNCFNFSTHVTKWFAEDPSRTYHDLAQYWVDHAVPIFQNYSQERRLVMWEDIALSADNAHDVPKNIVMQSWNNGLEYISNLTARGYDVIVSSSDFLYLDCGHGGFVTNDPRYNVMANPDANTPNFNYGGNGGSWCAPYKTWQRIYDYDFTLNLTETQAKHIIGATAPLWGEQVDDINVSSMFWPRAAALAELVWSGNRDANGNKRTTEMTQRILNFREYLVANGVQAQALVPKYCLQHPHACDLYRNQAAI 5oar D 2.30 BS01 TBR D 1 N318 Y321 E322 N216 Y219 E220 3.2.1.52 Q8J2T0 29239122 SNSLQYVNVQVKDIEADLQHGVDESYTLDVEEDSDTITINAETVWGALHAFTTLQQLVISDGHGGLIIEEPVNIKDSPLYPYRGIMLDTGRNFVSLPKIFEQLEGMSLSKLNVLHWHIDDAQSWPIWVDVYPEMVKDAYSPHEIYSRNDVRNIVNYARARGIRVIPEIDMPSHSSSGWKQVDPEMVTCTDSWWSNDDWPLHTAVEPNPGQLDIIYNKTYEVVGNVYKELSDIFPDHWFHVGGDEIQPNCFNFSTHVTKWFAEDPSRTYHDLAQYWVDHAVPIFQNYSQERRLVMWEDIALSADNAHDVPKNIVMQSWNNGLEYISNLTARGYDVIVSSSDFLYLDCGHGGFVTNDPRYNVMANPDANTPNFNYGGNGGSWCAPYKTWQRIYDYDFTLNLTETQAKHIIGATAPLWGEQVDDINVSSMFWPRAAALAELVWSGNRDANGNKRTTEMTQRILNFREYLVANGVQAQALVPKYCLQHPHACDLYRNQAAIQ 5oar D 2.30 BS02 NGT D 1 R193 H275 E307 D345 E346 W419 Y445 D447 W482 W517 E519 R91 H173 E205 D243 E244 W317 Y343 D345 W380 W415 E417 3.2.1.52 Q8J2T0 29239122 SNSLQYVNVQVKDIEADLQHGVDESYTLDVEEDSDTITINAETVWGALHAFTTLQQLVISDGHGGLIIEEPVNIKDSPLYPYRGIMLDTGRNFVSLPKIFEQLEGMSLSKLNVLHWHIDDAQSWPIWVDVYPEMVKDAYSPHEIYSRNDVRNIVNYARARGIRVIPEIDMPSHSSSGWKQVDPEMVTCTDSWWSNDDWPLHTAVEPNPGQLDIIYNKTYEVVGNVYKELSDIFPDHWFHVGGDEIQPNCFNFSTHVTKWFAEDPSRTYHDLAQYWVDHAVPIFQNYSQERRLVMWEDIALSADNAHDVPKNIVMQSWNNGLEYISNLTARGYDVIVSSSDFLYLDCGHGGFVTNDPRYNVMANPDANTPNFNYGGNGGSWCAPYKTWQRIYDYDFTLNLTETQAKHIIGATAPLWGEQVDDINVSSMFWPRAAALAELVWSGNRDANGNKRTTEMTQRILNFREYLVANGVQAQALVPKYCLQHPHACDLYRNQAAIQ 5oc7 D 1.65 BS01 IP2 D 1 K739 K754 K33 K40 2.7.11.1,2.7.11.1 P11274 29235475 RQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKQYDCKWYIPLTDLSFQMVDEPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSC 5oce A 2.41 BS01 BMA A 1 Y83 W84 H126 W130 F160 R164 Y44 W45 H87 W91 F121 R125 2.3.1.- A0QWG5 29185694 GARYAARNGGPEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADL 5oce B 2.41 BS01 9R2 B 1 Y83 W84 V104 L122 L124 H126 W130 D131 A133 G134 L137 F144 T146 F160 R164 F169 C196 M198 V237 Y36 W37 V57 L75 L77 H79 W83 D84 A86 G87 L90 F97 T99 F113 R117 F122 C149 M151 V190 2.3.1.- A0QWG5 29185694 GGPEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADLSDERR 5oce C 2.41 BS01 9R2 C 1 W84 V104 L124 H126 W130 A133 G134 L137 F144 T146 F160 R164 C196 M198 V237 V250 W37 V57 L77 H79 W83 A86 G87 L90 F97 T99 F113 R117 C149 M151 V190 V203 2.3.1.- A0QWG5 29185694 GGPEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADL 5oce D 2.41 BS01 9R2 D 1 Y83 W84 V104 L124 H126 W130 A133 G134 F144 F160 R164 C196 M198 V237 M248 Y44 W45 V65 L85 H87 W91 A94 G95 F105 F121 R125 C157 M159 V198 M209 2.3.1.- A0QWG5 29185694 GARYAARNGGPEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADL 5omy A 1.95 BS01 9YE A 1 L45 G46 G48 S51 V53 V66 K68 I95 N118 D120 H160 M163 I174 D175 L44 G45 G47 S50 V52 V65 K67 I94 N117 D119 H159 M162 I173 D174 2.7.11.1 P68400 29236079 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQAR 5ona B 2.70 BS01 III C 1 A84 N88 Q98 R130 E133 Y134 L137 T138 G141 G144 K148 L177 T180 V181 F184 R227 K230 H231 A72 N76 Q86 R118 E121 Y122 L125 T126 G129 G132 K136 L165 T168 V169 F172 R215 K218 H219 Q92600 29255063 GPHMLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5ona E 2.70 BS01 III F 1 A84 N88 R130 E133 Y134 L137 T138 G141 G144 K148 L177 V181 F184 K230 H231 A70 N74 R116 E119 Y120 L123 T124 G127 G130 K134 L163 V167 F170 K216 H217 Q92600 29255063 HMLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5onb A 3.00 BS01 III B 1 R46 E47 A84 H85 N88 Q98 R130 E133 Y134 L137 T138 G141 G144 A145 K148 L177 T180 V181 F184 R227 K230 H231 R31 E32 A69 H70 N73 Q83 R115 E118 Y119 L122 T123 G126 G129 A130 K133 L162 T165 V166 F169 R212 K215 H216 Q92600 29255063 MLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5onb C 3.00 BS01 III D 1 A84 H85 S87 N88 Q98 R130 E133 Y134 L137 T138 G141 G144 A145 L177 V181 F184 R227 K230 H231 A67 H68 S70 N71 Q81 R113 E116 Y117 L120 T121 G124 G127 A128 L160 V164 F167 R210 K213 H214 Q92600 29255063 EREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5onb E 3.00 BS01 III F 1 L40 E47 A84 H85 N88 Q98 R130 E133 Y134 L137 T138 G141 G144 K148 L177 V181 F184 H231 L24 E31 A68 H69 N72 Q82 R114 E117 Y118 L121 T122 G125 G128 K132 L161 V165 F168 H215 Q92600 29255063 LEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5onb G 3.00 BS01 III H 1 L40 E47 A84 H85 N88 Q98 R130 E133 Y134 L137 T138 G141 G144 A145 K148 L177 V181 F184 R227 H231 L25 E32 A69 H70 N73 Q83 R115 E118 Y119 L122 T123 G126 G129 A130 K133 L162 V166 F169 R212 H216 Q92600 29255063 MLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5oni A 2.00 BS01 9YE A 1 G46 R47 G48 V53 V66 K68 I95 F113 E114 V116 N118 M163 I174 D175 G45 R46 G47 V52 V65 K67 I94 F112 E113 V115 N117 M162 I173 D174 2.7.11.1 P68400 29236079 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMG 5oni B 2.00 BS01 9YE B 1 V53 V66 K68 I95 F113 V116 N118 M163 I174 D175 V52 V65 K67 I94 F112 V115 N117 M162 I173 D174 2.7.11.1 P68400 29236079 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMG 5ooi A 2.00 BS01 9YE A 1 L46 G47 R48 G49 V54 V67 K69 I96 F114 E115 Y116 I117 N119 M164 I175 D176 L42 G43 R44 G45 V50 V63 K65 I92 F110 E111 Y112 I113 N115 M160 I171 D172 2.7.11.1 P19784 29236079 AAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQS 5ooi B 2.00 BS01 9YE B 1 L46 R48 G49 V54 V67 K69 I96 F114 E115 Y116 I117 N119 M164 I175 D176 L40 R42 G43 V48 V61 K63 I90 F108 E109 Y110 I111 N113 M158 I169 D170 2.7.11.1 P19784 29236079 GSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKE 5sxg A 1.93 BS01 ZN A 1 H253 C284 C289 H48 C79 C84 3.5.4.- Q9UH17 29234087 RYLMDPDTFTSNFNNDPLVLRRRQTYLCYEVERLDQHMGFLCNESGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 5sxg A 1.93 BS02 PDO A 1 R212 Q213 T214 N240 H253 W281 S282 C284 Y313 R23 Q24 T25 N43 H48 W76 S77 C79 Y108 3.5.4.- Q9UH17 29234087 RYLMDPDTFTSNFNNDPLVLRRRQTYLCYEVERLDQHMGFLCNESGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 5sxg A 1.93 BS03 PDO A 2 R211 R212 Q213 N240 E241 S250 G251 R22 R23 Q24 N43 E44 S45 G46 3.5.4.- Q9UH17 29234087 RYLMDPDTFTSNFNNDPLVLRRRQTYLCYEVERLDQHMGFLCNESGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 5sxg B 1.93 BS01 ZN B 1 H253 C284 C289 H47 C78 C83 3.5.4.- Q9UH17 29234087 RYLMDPDTFTSNFNNDPLVLRRRQTYLCYEVERDQHMGFLCNESGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 5sxg B 1.93 BS02 PDO B 1 R212 Q213 T214 N240 H253 W281 S282 C284 Y313 R23 Q24 T25 N42 H47 W75 S76 C78 Y107 3.5.4.- Q9UH17 29234087 RYLMDPDTFTSNFNNDPLVLRRRQTYLCYEVERDQHMGFLCNESGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 5sxg B 1.93 BS03 PDO B 2 I312 D314 Y319 L369 R372 I106 D108 Y113 L163 R166 3.5.4.- Q9UH17 29234087 RYLMDPDTFTSNFNNDPLVLRRRQTYLCYEVERDQHMGFLCNESGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 5sxg B 1.93 BS04 PDO B 3 V208 L209 R210 W281 Y315 V19 L20 R21 W75 Y109 3.5.4.- Q9UH17 29234087 RYLMDPDTFTSNFNNDPLVLRRRQTYLCYEVERDQHMGFLCNESGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 5sxh A 1.78 BS01 ZN A 1 H253 C284 C289 H49 C80 C85 3.5.4.- Q9UH17 29234087 RYLMDPDTFTSNFNNDPLVLRRRQTYLCYEVERLDDQHMGFLCNESGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 5sxh B 1.78 BS01 ZN B 1 H253 C284 C289 H48 C79 C84 3.5.4.- Q9UH17 29234087 RYLMDPDTFTSNFNNDPLVLRRRQTYLCYEVERLDQHMGFLCNESGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 5tfk A 2.80 BS01 CA A 1 N1930 N1932 D1966 D1968 Y1972 D2022 N2 N4 D38 D40 Y44 D94 Q99PF4 ENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDV 5tfk A 2.80 BS02 CA A 2 E1947 D2005 R2006 E2007 D2041 E19 D77 R78 E79 D113 Q99PF4 ENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDV 5tfk A 2.80 BS03 CA A 3 E1947 E2007 D2038 D2039 D2041 D2074 E19 E79 D110 D111 D113 D146 Q99PF4 ENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDV 5tfk A 2.80 BS04 CA A 4 E2162 D2262 V2263 E234 D334 V335 Q99PF4 ENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDV 5tfk A 2.80 BS05 CA A 5 N2040 N2042 D2072 D2074 N2078 D2125 N112 N114 D144 D146 N150 D197 Q99PF4 ENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDV 5tfk A 2.80 BS06 CA A 6 E2057 D2110 E2112 D2146 E129 D182 E184 D218 Q99PF4 ENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDV 5tfk A 2.80 BS07 CA A 7 E2057 E2112 D2143 I2144 D2146 D2179 E129 E184 D215 I216 D218 D251 Q99PF4 ENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDV 5tfk A 2.80 BS08 CA A 8 N2145 S2147 D2177 D2179 D2239 N217 S219 D249 D251 D311 Q99PF4 ENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDV 5tfl A 3.56 BS01 CA A 1 E659 E714 D747 I748 D750 N751 D783 E15 E60 D88 I89 D91 N92 D124 Q99PF4 PPTFSKPAYFVSVLENIMAGATVLFLNATDSIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIHPPNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLN 5tfl A 3.56 BS02 CA A 2 N749 N751 D781 D783 N787 D839 N90 N92 D122 D124 N128 D180 Q99PF4 PPTFSKPAYFVSVLENIMAGATVLFLNATDSIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIHPPNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLN 5tfl B 3.56 BS01 CA B 1 E659 E714 D747 I748 D750 D783 E15 E59 D85 I86 D88 D121 Q99PF4 PPTFSKPAYFVSVLENIMAGATVLFLNATSIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIHPPNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDL 5tfl B 3.56 BS02 CA B 2 N749 N751 D781 D783 N787 D839 N87 N89 D119 D121 N125 D177 Q99PF4 PPTFSKPAYFVSVLENIMAGATVLFLNATSIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIHPPNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDL 5tfm A 2.92 BS01 CA A 1 N642 N644 D674 D676 Y681 D727 N104 N106 D136 D138 Y143 D189 Q9H251 NVPTFQKDAYVGALRENEPSVTQLVRLRATDEDQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLL 5tfm A 2.92 BS02 CA A 2 E549 E607 D640 E641 D643 D676 E16 E69 D102 E103 D105 D138 Q9H251 NVPTFQKDAYVGALRENEPSVTQLVRLRATDEDQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLL 5tfm A 2.92 BS03 CA A 3 E549 N550 D605 E607 D643 E16 N17 D67 E69 D105 Q9H251 NVPTFQKDAYVGALRENEPSVTQLVRLRATDEDQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLL 5tfm A 2.92 BS04 CA A 4 E659 E714 D747 I748 D750 D783 E121 E176 D209 I210 D212 D245 Q9H251 NVPTFQKDAYVGALRENEPSVTQLVRLRATDEDQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLL 5tfm A 2.92 BS05 CA A 5 N749 N751 D781 D783 N787 D839 N211 N213 D243 D245 N249 D301 Q9H251 NVPTFQKDAYVGALRENEPSVTQLVRLRATDEDQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLL 5ubv A 2.45 BS01 ADP A 1 D7 H9 G49 T50 G51 K52 T53 L54 H185 G209 A210 E213 D7 H9 G48 T49 G50 K51 T52 L53 H183 G207 A208 E211 G2QPI5 SNARFSDVHGCDEAKEELQELVEFLRNPEKFSNLGKLPKGVLLVGPPGTGKTLLARAVAGEAGVPFFYMSGSEFDEIVGVGAKRVRELFNAAKAKAPSIVFIDELDAIGGRRNSRDATYVRQTLNQLLTEMDGFAQNSGVIILGATNFPESLDKALTRPGRFDRHVHVSLPDVRGRIAILKHHAKKIKIGSDVNIAAIAARTSGLSGAELENIVNQAAVHASKEKAKAVMQAHFEWAKDKVIMG 5ubv B 2.45 BS01 ADP B 1 D7 V8 H9 G49 T50 G51 K52 T53 L54 I181 H185 G209 A210 E213 D6 V7 H8 G48 T49 G50 K51 T52 L53 I174 H178 G202 A203 E206 G2QPI5 NARFSDVHGCDEAKEELQELVEFLRNPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAGVPFFYMSGSEFDEIYVGVGAKRVRELFNAAKAKAPSIVFIDELDAIGGRRYVRQTLNQLLTEMDGFAQNSGVIILGATNFPESLDKALTRPGRFDRHVHVSLPDVRGRIAILKHHAKKIKIGSDVNIAAIAARTSGLSGAELENIVNQAAVHASKEKAKAVMQAHFEWAKDKVIM 5uc1 A 2.35 BS01 486 A 1 L559 N560 G563 G564 Q566 V567 M600 R607 F619 Q638 C639 M642 L40 N41 G44 G45 Q47 V48 M81 R88 F98 Q117 C118 M121 TLPQLTPTLVSLLEVIEPEVLYAGYDGTVPDTTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQGNVLCFAPDLIINEQRMGLPYMYDQCKQMLFVSSELKRLQVSYEEYLCMKTLLLFSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHENVT 5uc1 B 2.35 BS01 486 A 1 W553 M556 W34 M37 TLPQLTPTLVSLLEVIEPEVLYAGYDGTVPDTTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQGNVLCFAPDLIINEQRMGLPYMYDQCKQMLFVSSELKRLQVSYEEYLCMKTLLLFSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHENVT 5uc1 B 2.35 BS02 486 B 1 L559 N560 G563 G564 Q566 V567 M600 R607 F619 C639 M642 L40 N41 G44 G45 Q47 V48 M81 R88 F98 C118 M121 TLPQLTPTLVSLLEVIEPEVLYAGYDGTVPDTTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQGNVLCFAPDLIINEQRMGLPYMYDQCKQMLFVSSELKRLQVSYEEYLCMKTLLLFSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHENVT 5uc3 A 2.01 BS01 486 A 1 M560 L563 N564 G567 Q570 W600 M601 M604 R611 F623 M639 Q642 M646 C736 M35 L38 N39 G42 Q45 W75 M76 M79 R86 F98 M114 Q117 M121 C211 P04150 PQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLKPYCFQTFLDKTMSIGNIKKLLFHQ 5uc3 B 2.01 BS01 486 B 1 M560 L563 N564 G567 Q570 W600 M601 M604 R611 F623 Q642 M646 L732 C736 M35 L38 N39 G42 Q45 W75 M76 M79 R86 F97 Q116 M120 L206 C210 P04150 PQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLKPYCFQTFLDKTMSIGNIKKLLFHQ 5ud6 A 2.40 BS01 CA A 1 A52 S58 E66 G87 A45 S51 E59 G80 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLL 5ud6 A 2.40 BS02 LYS A 1 S58 A59 L61 W63 E66 Y117 S51 A52 L54 W56 E59 Y110 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLL 5ud6 A 2.40 BS03 LYS B 1 N91 E95 N84 E88 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLL 5ud6 B 2.40 BS01 LYS A 1 N91 E95 N84 E88 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLL 5ud6 B 2.40 BS02 CA B 1 A52 S58 E66 G87 A45 S51 E59 G80 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLL 5ud6 B 2.40 BS03 LYS B 1 S58 A59 L61 W63 E66 Y117 S51 A52 L54 W56 E59 Y110 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLL 5ud6 C 2.40 BS01 CA C 1 A52 S58 E66 G87 A45 S51 E59 G80 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLLS 5ud6 C 2.40 BS02 LYS C 1 S58 A59 W63 E66 Y117 S51 A52 W56 E59 Y110 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLLS 5ud6 C 2.40 BS03 LYS D 1 N91 E95 N84 E88 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLLS 5ud6 D 2.40 BS01 LYS C 1 N91 E95 N84 E88 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLLS 5ud6 D 2.40 BS02 CA D 1 A52 S58 E66 G87 A45 S51 E59 G80 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLLS 5ud6 D 2.40 BS03 LYS D 1 S58 A59 L61 W63 E66 Y117 S51 A52 L54 W56 E59 Y110 M1V4H9 KHFFGRVITALVTPFKLTGVEVDYGVAESLAAHLAENGSDAIIVAGTTGESATLTWSEEYELFRVVKSAVAGTKCRVIAGAGSNSTEEAIEATKKSAKLGLDGTLQVVPYYNKPPQQGIMAHFRAIANAAPDLPMMLYNIPGRTGINMTAETSIKLAEMCPNIVALKEASGNLEQFARIRRATSPDFALYSGDDALTLPLLSLGGNGVVSVASHFIGPEIQRMIEHFVDLGNPEEAFRIHCRYMDLFEALFVMANPIPAKAALRLLGWPVGPTRLPLTDITASAEQQLRQAMIAAGLLS 5uht A 2.68 BS01 ADP A 1 N380 Y384 D411 I416 Y429 R430 V431 G441 T442 G443 G445 L446 F472 N137 Y141 D168 I173 Y186 R187 V188 G198 T199 G200 G202 L203 F229 Q9WZV7 29235472 LKRIDRMKTEFIANISHELRTPLTAIKAYAETIYNSLGELDLSTLKEFLEVIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEFASSHNVNVLFESNVPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKYVKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSSLTYEVPGTGLGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPKDR 5uht B 2.68 BS01 MG B 1 D10 D53 M55 D10 D53 M55 Q9WYT9 29235472 MSKKVLLVDDSAVLRKIVSFNLKKEGYEVIEAENGQIALEKLSEFTPDLIVLDIMMPVMDGFTVLKKLQEKEEWKRIPVIVLTAKGGEEDESLALSLGARKVMRKPFSPSQFIEEVKHLLN 5uht C 2.68 BS01 ADP C 1 N380 K383 Y384 D411 I416 I424 Y429 R430 V431 G441 T442 G443 G445 L446 F472 N137 K140 Y141 D168 I173 I181 Y186 R187 V188 G198 T199 G200 G202 L203 F229 Q9WZV7 29235472 LKRIDRMKTEFIANISHELRTPLTAIKAYAETIYNSLGELDLSTLKEFLEVIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEFASSHNVNVLFESNVPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKYVKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSSLTYEVPGTGLGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPKDR 5uht D 2.68 BS01 MG D 1 D10 D53 M55 D10 D53 M55 Q9WYT9 29235472 MSKKVLLVDDSAVLRKIVSFNLKKEGYEVIEAENGQIALEKLSEFTPDLIVLDIMMPVMDGFTVLKKLQEKEEWKRIPVIVLTAKGGEEDESLALSLGARKVMRKPFSPSQFIEEVKHLLN 5ujx B 1.80 BS01 IPA B 1 A117 E118 H149 A117 E118 H149 1.5.1.3 C3TR70 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5umz B 1.90 BS01 III E 1 G281 N283 I286 R315 N319 V321 T322 G323 T328 E354 W357 S360 N361 A364 E396 W399 N403 G210 N212 I215 R244 N248 V250 T251 G252 T257 E283 W286 S289 N290 A293 E325 W328 N332 P52293 28837617 GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 5umz B 1.90 BS02 III D 1 L104 S105 R106 E107 P110 W142 N146 A148 S149 G150 T151 T155 Q181 W184 N188 G191 D192 W231 N235 R238 D270 L33 S34 R35 E36 P39 W71 N75 A77 S78 G79 T80 T84 Q110 W113 N117 G120 D121 W160 N164 R167 D199 P52293 28837617 GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 5upk B 2.40 BS01 ANP B 1 E329 G330 V335 A348 K350 M395 E396 F397 L398 L447 E30 G31 V36 A49 K51 M96 E97 F98 L99 L148 2.7.11.1 O96013 SHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQN 5upk C 2.40 BS01 GNP C 1 A13 G15 K16 T17 C18 F28 E31 Y32 T35 G60 L61 Q116 D118 L119 S158 A159 A12 G14 K15 T16 C17 F27 E30 Y31 T34 G59 L60 Q115 D117 L118 S154 A155 P60953 QTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGLEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALLE 5upk C 2.40 BS02 MG C 1 T17 V33 T35 T16 V32 T34 P60953 QTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGLEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALLE 5vfn A 2.39 BS01 HCI A 1 K16 K20 K115 R118 K15 K19 K105 R108 Q9IAT9 28751219 SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGQPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKADPC 5vgt A 1.78 BS01 MG A 1 A112 T115 D116 A110 T113 D114 Q716G8 TVLTKGEIVLFALRKFAIASNASLTDVEPQSIEDGVNDLEDMMSEWMINPGDIGYAFATGDEQPLPDDESGLPRKYKHAVGYQLLLRMLSDYSLEPTPQVLSNAQRSYDALMTDTLVVPSMRLE 5vgt B 1.78 BS01 CA B 1 D43 E47 D40 E44 Q716G8 VLTKGEIVLFALRKFAIASNASLTDVEPQSIEDGVNDLEDMMSEWMINPGDIGYAFATGDEQPLPDDESGLPRKYKHAVGYQLLLRMLSDYSLEPTPQVLSNAQRSYDALMTD 5vjn A 1.78 BS01 IR8 A 1 R69 K90 D129 D130 I131 A133 T134 G135 S137 R67 K88 D127 D128 I129 A131 T132 G133 S135 2.4.2.7 P49435 29178779 IASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLL 5vjn A 1.78 BS02 EDO A 1 L51 E52 F55 V58 I60 L81 L49 E50 F53 V56 I58 L79 2.4.2.7 P49435 29178779 IASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLL 5vjn A 1.78 BS03 EDO A 2 K59 I60 L81 V83 K57 I58 L79 V81 2.4.2.7 P49435 29178779 IASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLL 5vjn A 1.78 BS04 ADE A 1 L26 F27 E28 R69 I131 A133 L161 L24 F25 E26 R67 I129 A131 L159 2.4.2.7 P49435 29178779 IASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLL 5vjn B 1.78 BS01 EDO A 3 L31 P32 R35 L29 P30 R33 2.4.2.7 P49435 29178779 IASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLL 5vjn B 1.78 BS02 IR8 B 1 D129 D130 I131 A133 T134 G135 S137 D120 D121 I122 A124 T125 G126 S128 2.4.2.7 P49435 29178779 IASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLL 5vjn B 1.78 BS03 EDO B 1 L51 E52 F55 V58 I60 L49 E50 F53 V56 I58 2.4.2.7 P49435 29178779 IASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLL 5vjn B 1.78 BS04 EDO B 2 K59 I60 L81 V83 K57 I58 L79 V81 2.4.2.7 P49435 29178779 IASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLL 5vjp A 1.98 BS01 IR9 A 1 R69 D129 D130 I131 A133 T134 G135 G136 S137 R69 D122 D123 I124 A126 T127 G128 G129 S130 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vjp A 1.98 BS02 EDO A 1 L51 E52 F55 V58 I60 L51 E52 F55 V58 I60 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vjp A 1.98 BS03 EDO A 2 K59 I60 L81 V83 K59 I60 L81 V83 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vjp A 1.98 BS04 EDO B 1 Q115 A118 Q108 A111 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vjp A 1.98 BS05 EDO B 2 P32 R35 P32 R35 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vjp B 1.98 BS01 IR9 B 1 R69 D129 D130 I131 A133 T134 G135 G136 S137 R69 D129 D130 I131 A133 T134 G135 G136 S137 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vjp B 1.98 BS02 EDO B 3 F55 P56 V58 I60 F55 P56 V58 I60 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vjp B 1.98 BS03 EDO B 4 K59 I60 L81 V83 K59 I60 L81 V83 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vjp B 1.98 BS04 EDO B 5 A54 F55 E154 P173 A54 F55 E154 P173 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vjp B 1.98 BS05 ADE B 1 L26 F27 E28 R69 I131 A133 L161 L26 F27 E28 R69 I131 A133 L161 2.4.2.7 P49435 29178779 MPIASYAQELKLALHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRGFLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATGGSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPVFTLLN 5vlx A 1.80 BS01 HEM A 1 F24 E31 N34 F35 H55 K58 V59 M63 L83 M86 Q88 H89 L92 N96 F97 L127 F24 E31 N34 F35 H55 K58 V59 M63 L83 M86 Q88 H89 L92 N96 F97 L127 Q9NAV7 29170897 GFKQDIATLRGDLRTYAQDIWLAFLNKYPDEKRNFKNYVGKSDQELKSMAKFGDHTEKVFNLMMEVADRATDCVPLASDASTLVQMKQHSGLTTGNFEKLFVALVEYMRASGQSFDSQSWDRFGKNLVSALSSAGMK 5vlx B 1.80 BS01 HEM B 1 F24 E31 N34 F35 H55 K58 V59 L62 M63 L83 M86 Q88 H89 L92 N96 F97 L100 L127 F24 E31 N34 F35 H55 K58 V59 L62 M63 L83 M86 Q88 H89 L92 N96 F97 L100 L127 Q9NAV7 29170897 GFKQDIATLRGDLRTYAQDIWLAFLNKYPDEKRNFKNYVGKSDQELKSMAKFGDHTEKVFNLMMEVADRATDCVPLASDASTLVQMKQHSGLTTGNFEKLFVALVEYMRASGQSFDSQSWDRFGKNLVSALSSAGMK 5vp1 A 1.86 BS01 ZN A 1 H660 H696 D697 D808 H82 H118 D119 D230 3.1.4.17 O00408 29093293 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5vp1 A 1.86 BS02 9GA A 1 H656 T768 L770 H773 T805 D808 L809 Q812 I826 Y827 F830 M847 L858 Q859 F862 I866 I870 H78 T190 L192 H195 T227 D230 L231 Q234 I248 Y249 F252 M269 L280 Q281 F284 I288 I292 3.1.4.17 O00408 29093293 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5vp1 B 1.86 BS01 ZN B 1 H660 H696 D697 D808 H86 H122 D123 D234 3.1.4.17 O00408 29093293 GHASDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5vp1 B 1.86 BS02 9GA B 1 H656 T768 L770 H773 T805 D808 L809 Q812 I826 Y827 M847 L858 Q859 F862 I866 I870 H82 T194 L196 H199 T231 D234 L235 Q238 I252 Y253 M273 L284 Q285 F288 I292 I296 3.1.4.17 O00408 29093293 GHASDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5vp1 C 1.86 BS01 ZN C 1 H660 H696 D697 D808 H71 H107 D108 D205 3.1.4.17 O00408 29093293 IQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5vp1 C 1.86 BS02 9GA C 1 H656 T768 L770 H773 T805 D808 L809 Q812 I826 Y827 M847 L858 Q859 F862 I866 I870 H67 T165 L167 H170 T202 D205 L206 Q209 I223 Y224 M244 L255 Q256 F259 I263 I267 3.1.4.17 O00408 29093293 IQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5vtb A 2.40 BS01 III B 1 H38 A39 E41 W42 P43 H71 T72 I117 K120 E126 N128 R129 E179 Y181 E231 F321 E395 N397 H14 A15 E17 W18 P19 H43 T44 I65 K68 E74 N76 R77 E127 Y129 E179 F269 E333 N335 Q09028 KKNTPFLYDLVMTHALEWPSLTAQWLPDVTKDFSIHRLVLGTHTSDEQNHLVIASVQLPNGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYND 5w3i A 1.95 BS01 MN A 1 H41 D108 E119 I120 H41 D89 E100 I101 C3W5S0 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERAAAEL 5w3i A 1.95 BS02 MN A 2 H41 E80 D108 H41 E61 D89 C3W5S0 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERAAAEL 5w3i A 1.95 BS03 GY5 A 1 I38 H41 E80 D108 E119 I120 K134 I38 H41 E61 D89 E100 I101 K115 C3W5S0 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERAAAEL 5w4r A 3.00 BS01 9WD A 1 C320 H323 M358 M365 V376 F377 F378 E379 F388 L396 I400 F401 C56 H59 M94 M101 V112 F113 F114 E115 F124 L132 I136 F137 P51449 29079472 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQ 5w4r B 3.00 BS01 9WD B 1 C320 H323 L324 A327 M358 L362 M365 A368 V376 F377 F378 E379 F388 L396 I400 F401 L475 Q478 H479 C56 H59 L60 A63 M94 L98 M101 A104 V112 F113 F114 E115 F124 L132 I136 F137 L211 Q214 H215 P51449 29079472 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVE 5w4v A 2.65 BS01 9WA A 1 Q286 L287 C320 H323 L324 V361 L362 M365 V376 F377 F378 E379 G380 F388 I400 F401 Q20 L21 C54 H57 L58 V95 L96 M99 V110 F111 F112 E113 G114 F122 I134 F135 P51449 29079472 LTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPPKGKLRSL 5w4v A 2.65 BS02 9WA B 1 M313 W314 W317 M47 W48 W51 P51449 29079472 LTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPPKGKLRSL 5w4v B 2.65 BS01 9WA A 1 M313 W314 W317 M47 W48 W51 P51449 29079472 LTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPPKGKLRSL 5w4v B 2.65 BS02 9WA B 1 Q286 L287 C320 H323 L324 A327 V361 L362 M365 V376 F377 F378 E379 G380 F388 I400 F401 Q20 L21 C54 H57 L58 A61 V95 L96 M99 V110 F111 F112 E113 G114 F122 I134 F135 P51449 29079472 LTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPPKGKLRSL 5w4v C 2.65 BS01 9WA C 1 C320 H323 L324 V361 M365 V376 F377 F378 E379 G380 F388 L396 I400 F401 C51 H54 L55 V92 M96 V107 F108 F109 E110 G111 F119 L127 I131 F132 P51449 29079472 IEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPPKGKLRSL 5w4v C 2.65 BS02 9WA F 1 M313 W314 W317 M44 W45 W48 P51449 29079472 IEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPPKGKLRSL 5w4v D 2.65 BS01 9WA D 1 Q286 L287 C320 H323 L324 A327 V361 M365 V376 F377 F378 E379 G380 F388 I400 F401 Q21 L22 C55 H58 L59 A62 V96 M100 V111 F112 F113 E114 G115 F123 I135 F136 P51449 29079472 SLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPP 5w4v D 2.65 BS02 9WA E 1 W314 W317 W49 W52 P51449 29079472 SLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPP 5w4v E 2.65 BS01 9WA D 1 W314 W317 W48 W51 P51449 29079472 LTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPPKGKL 5w4v E 2.65 BS02 9WA E 1 Q286 L287 C320 H323 L324 A327 V361 L362 M365 V376 F377 F378 E379 G380 F388 I400 F401 Q20 L21 C54 H57 L58 A61 V95 L96 M99 V110 F111 F112 E113 G114 F122 I134 F135 P51449 29079472 LTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPPKGKL 5w4v F 2.65 BS01 9WA C 1 M313 W317 M47 W51 P51449 29079472 LTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPP 5w4v F 2.65 BS02 9WA F 1 Q286 L287 C320 H323 L324 L362 M365 V376 F377 F378 E379 G380 F388 I400 F401 Q20 L21 C54 H57 L58 L96 M99 V110 F111 F112 E113 G114 F122 I134 F135 P51449 29079472 LTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPP 5w7u A 2.20 BS01 MN A 1 H41 D108 E119 I120 H45 D93 E104 I105 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5w7u A 2.20 BS02 MN A 2 H41 E80 D108 E119 H45 E65 D93 E104 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5w7u A 2.20 BS03 GY8 A 1 A20 Y24 K34 A37 I38 H41 E80 D108 E119 I120 K134 A24 Y28 K38 A41 I42 H45 E65 D93 E104 I105 K119 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5w9g A 2.10 BS01 MN A 1 H41 D108 E119 I120 H45 D93 E104 I105 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5w9g A 2.10 BS02 MN A 2 H41 E80 D108 H45 E65 D93 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5w9g A 2.10 BS03 KU2 A 1 M21 Y24 E26 A37 I38 H41 E80 D108 E119 I120 Y130 M25 Y28 E30 A41 I42 H45 E65 D93 E104 I105 Y115 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5we9 A 1.80 BS01 MN A 1 H41 D108 E119 I120 K134 H41 D89 E100 I101 K115 C3W5S0 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERA 5we9 A 1.80 BS02 MG A 1 E80 D108 E61 D89 C3W5S0 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERA 5we9 A 1.80 BS03 GY7 A 1 Y24 H41 E80 D108 E119 I120 K134 K137 Y24 H41 E61 D89 E100 I101 K115 K118 C3W5S0 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERA 5wef A 2.00 BS01 MN A 1 H41 D108 E119 I120 H41 D89 E100 I101 C3W5S0 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKSLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERA 5wef A 2.00 BS02 MN A 2 H41 E80 D108 H41 E61 D89 C3W5S0 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKSLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERA 5wef A 2.00 BS03 GY6 A 1 A20 Y24 E26 K34 I38 H41 E80 D108 E119 I120 K134 A20 Y24 E26 K34 I38 H41 E61 D89 E100 I101 K115 C3W5S0 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKSLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERA 5wei A 2.25 BS01 MN A 1 H41 D108 D119 I120 H45 D93 D104 I105 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wei A 2.25 BS02 MN A 2 H41 E80 D108 H45 E65 D93 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wei A 2.25 BS03 GY6 A 1 Y24 K34 H41 E80 D108 D119 I120 Y28 K38 H45 E65 D93 D104 I105 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wfz A 2.35 BS01 MN A 1 H41 D108 D119 I120 H44 D92 D103 I104 C3W5S0 29215062 GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wfz A 2.35 BS02 MN A 2 H41 E80 D108 H44 E64 D92 C3W5S0 29215062 GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wfz A 2.35 BS03 KU0 A 1 Y24 K34 I38 H41 E80 F105 L106 D108 D119 I120 K134 Y27 K37 I41 H44 E64 F89 L90 D92 D103 I104 K118 C3W5S0 29215062 GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wg3 A 2.90 BS01 AFM A 1 G198 R199 G200 F202 G203 V205 A218 K220 E239 V255 D272 M274 D278 A321 L324 D335 G169 R170 G171 F173 G174 V176 A189 K191 E210 V226 D243 M245 D249 A292 L295 D306 2.7.11.15 P25098 29070696 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRTKDKHEIDRMTLTVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5wg3 A 2.90 BS02 MG A 1 H348 E360 V361 Q363 V366 Y368 H319 E331 V332 Q334 V337 Y339 2.7.11.15 P25098 29070696 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRTKDKHEIDRMTLTVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5wg4 A 2.31 BS01 AFV A 1 I197 G198 R199 G200 G201 F202 G203 V205 A218 L222 L235 E239 D272 M274 D278 A321 L324 D335 A480 A482 I167 G168 R169 G170 G171 F172 G173 V175 A188 L192 L205 E209 D242 M244 D248 A291 L294 D305 A448 A450 2.7.11.15 P25098 29070696 KILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADATKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5wg5 A 3.10 BS01 ZSO A 1 I197 R199 G200 G203 V205 A218 K220 L222 V255 D272 M274 D278 A321 L324 I164 R166 G167 G170 V172 A185 K187 L189 V222 D239 M241 D245 A288 L291 2.7.11.15 P25098 29070696 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPVNAADAFDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5wg5 A 3.10 BS02 MG A 1 H348 E360 V361 Q363 V366 Y368 H315 E327 V328 Q330 V333 Y335 2.7.11.15 P25098 29070696 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPVNAADAFDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5whr A 2.28 BS01 HEM A 1 F163 S167 V170 F214 F226 A264 G265 F270 R343 H346 I349 V350 Y353 I354 G380 G381 T382 L384 F387 L388 V391 F150 S154 V157 F201 F213 A251 G252 F257 R330 H333 I336 V337 Y340 I341 G353 G354 T355 L357 F360 L361 V364 1.13.11.52 P14902 29111717 EYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQAKGTGGTDLMNFLKTVRSTTEKSLLKE 5whr A 2.28 BS02 AOJ A 1 Y126 C129 V130 F163 S167 F226 L234 G262 S263 A264 G378 T379 Y113 C116 V117 F150 S154 F213 L221 G249 S250 A251 G351 T352 1.13.11.52 P14902 29111717 EYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQAKGTGGTDLMNFLKTVRSTTEKSLLKE 5whr B 2.28 BS01 HEM B 1 Y126 F163 V170 F214 I217 F226 A264 G265 F270 R343 H346 I349 V350 Y353 I354 T379 G380 G381 T382 L384 F387 L388 V391 Y115 F152 V159 F203 I206 F215 A253 G254 F259 R332 H335 I338 V339 Y342 I343 T352 G353 G354 T355 L357 F360 L361 V364 1.13.11.52 P14902 29111717 SKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQKGTGGTDLMNFLKTVRSTTEKSLLK 5whr B 2.28 BS02 AOJ B 1 Y126 C129 V130 F163 S167 F226 L234 G262 S263 A264 G378 T379 Y115 C118 V119 F152 S156 F215 L223 G251 S252 A253 G351 T352 1.13.11.52 P14902 29111717 SKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQKGTGGTDLMNFLKTVRSTTEKSLLK 5wi3 B 1.81 BS01 PCZ B 1 A78 S79 L109 F110 W113 S126 V128 L166 T217 G218 W219 A220 M221 I223 R259 A48 S49 L74 F75 W78 S91 V93 L131 T182 G183 W184 A185 M186 I188 R224 3.5.2.6 I6YCI1 29229762 QIVQGHNQVIHQYFDEKNTSGVLVIQTDKKINLYGNALSRANTEYVPASTFDMLNALIGLENQKTDINEIFKRLFTAWEKDMTLGEAMKLSAVPVYQELARRIGLDLMQKEVKRIGFGNAEIGQQVDNFWLVGPLKVTPIQEVEFVSQLAHTQLPFSEKVQANVKNMLLLEESNGYKIFGKTGWAMNIKSQVGWLTGWVEQPDGKIVAFALNMEMRSEMPASIRNELLMKSLKQLNII 5wi3 A 1.81 BS01 PCZ A 1 A78 S79 F110 W113 S126 V128 L166 T217 G218 W219 A220 M221 R259 A48 S49 F80 W83 S96 V98 L136 T187 G188 W189 A190 M191 R229 3.5.2.6 I6YCI1 29229762 QIVQGHNQVIHQYFDEKNTSGVLVIQTDKKINLYGNALSRANTEYVPASTFDMLNALIGLENQKTDINEIFKWKGEKRLFTAWEKDMTLGEAMKLSAVPVYQELARRIGLDLMQKEVKRIGFGNAEIGQQVDNFWLVGPLKVTPIQEVEFVSQLAHTQLPFSEKVQANVKNMLLLEESNGYKIFGKTGWAMNIKSQVGWLTGWVEQPDGKIVAFALNMEMRSEMPASIRNELLMKSLKQLNII 5wi7 A 1.86 BS01 4J6 A 1 A78 S79 F110 W113 V128 L166 T217 G218 W219 M221 R259 A48 S49 F80 W83 V98 L136 T187 G188 W189 M191 R229 3.5.2.6 I6YCI1 29229762 QIVQGHNQVIHQYFDEKNTSGVLVIQTDKKINLYGNALSRANTEYVPASTFDMLNALIGLENQKTDINEIFKWKGEKRLFTAWEKDMTLGEAMKLSAVPVYQELARRIGLDLMQKEVKRIGFGNAEIGQQVDNFWLVGPLKVTPIQEVEFVSQLAHTQLPFSEKVQANVKNMLLLEESNGYKIFGKTGWAMNIKSQVGWLTGWVEQPDGKIVAFALNMEMRSEMPASIRNELLMKSLKQLNII 5wi7 B 1.86 BS01 4J6 B 1 A78 S79 F110 W113 S126 L166 T217 G218 W219 M221 P255 A256 R259 A43 S44 F70 W73 S86 L126 T177 G178 W179 M181 P215 A216 R219 3.5.2.6 I6YCI1 29229762 HNQVIHQYFDEKNTSGVLVIQTDKKINLYGNALSRANTEYVPASTFDMLNALIGLENQKTDINEIFKRLFTAWEKDMTLGEAMKLSAVPVYQELARRIGLDLMQKEVKRIGFGNAEIGQQVDNFWLVGPLKVTPIQEVEFVSQLAHTQLPFSEKVQANVKNMLLLEESNGYKIFGKTGWAMNIKSQVGWLTGWVEQPDGKIVAFALNMEMRSEMPASIRNELLMKSLKQLNII 5wib A 1.87 BS01 ID1 A 1 A78 S79 W113 S126 V128 L166 T217 G218 W219 M221 R259 A48 S49 W83 S96 V98 L136 T187 G188 W189 M191 R229 3.5.2.1 I6YCI1 29229762 QIVQGHNQVIHQYFDEKNTSGVLVIQTDKKINLYGNALSRANTEYVPASTFDMLNALIGLENQKTDINEIFKWKGEKRLFTAWEKDMTLGEAMKLSAVPVYQELARRIGLDLMQKEVKRIGFGNAEIGQQVDNFWLVGPLKVTPIQEVEFVSQLAHTQLPFSEKVQANVKNMLLLEESNGYKIFGKTGWAMNIKSQVGWLTGWVEQPDGKIVAFALNMEMRSEMPASIRNELLMKSLKQLNII 5wib B 1.87 BS01 ID1 B 1 A78 S79 W113 S126 V128 L166 T217 G218 W219 M221 R259 A49 S50 W78 S91 V93 L131 T182 G183 W184 M186 R224 3.5.2.1 I6YCI1 29229762 SQIVQGHNQVIHQYFDEKNTSGVLVIQTDKKINLYGNALSRANTEYVPASTFDMLNALIGLENQKTDINEIFRLFTAWEKDMTLGEAMKLSAVPVYQELARRIGLDLMQKEVKRIGFGNAEIGQQVDNFWLVGPLKVTPIQEVEFVSQLAHTQLPFSEKVQANVKNMLLLEESNGYKIFGKTGWAMNIKSQVGWLTGWVEQPDGKIVAFALNMEMRSEMPASIRNELLMKSLKQLNII 5wv4 A 1.80 BS01 CU A 1 H40 C78 H81 M86 H40 C78 H81 M86 P19567 ADFEVHMLNKGKDGAGVFEPASLKVAPGDTVTFIPTDKGHNVETIKGMIPDGAEAFKSKINENYKVTFTAPGVYGVKCTPHYGMGMVGVVQVGDAPANLEAVKGAKNPKKAQERLDAALAALGN 5wv4 B 1.80 BS01 CU B 1 H40 C78 H81 M86 H40 C78 H81 M86 P19567 ADFEVHMLNKGKDGAGVFEPASLKVAPGDTVTFIPTDKGHNVETIKGMIPDGAEAFKSKINENYKVTFTAPGVYGVKCTPHYGMGMVGVVQVGDAPANLEAVKGAKNPKKAQERLDAALAALGN 5wv9 A 2.11 BS01 NAG A 1 W102 F140 S177 W12 F50 S87 3.2.1.14 U5LUV7 DGYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLDIDWEYPKGGDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAPKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGAYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGNVKYPLIGAMREELRGISRGKDAKDVDWASVAASV 5wv9 A 2.11 BS02 NAG A 2 W102 F129 G175 W176 S177 E370 F373 W12 F39 G85 W86 S87 E280 F283 3.2.1.14 U5LUV7 DGYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLDIDWEYPKGGDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAPKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGAYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGNVKYPLIGAMREELRGISRGKDAKDVDWASVAASV 5wv9 A 2.11 BS03 NAG A 3 Y98 G175 W176 D215 E217 M283 Y285 D286 R342 W433 Y8 G85 W86 D125 E127 M193 Y195 D196 R252 W343 3.2.1.14 U5LUV7 DGYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLDIDWEYPKGGDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAPKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGAYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGNVKYPLIGAMREELRGISRGKDAKDVDWASVAASV 5wv9 A 2.11 BS04 NAG A 4 W176 D286 W291 R342 W86 D196 W201 R252 3.2.1.14 U5LUV7 DGYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLDIDWEYPKGGDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAPKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGAYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGNVKYPLIGAMREELRGISRGKDAKDVDWASVAASV 5wvb A 3.10 BS01 NAG A 1 Y218 D286 F287 W291 Y128 D196 F197 W201 3.2.1.14 U5LUV7 DGYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLDIDWLYPKGGDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAPKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGAYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGNVKYPLIGAMREELRGISRGKDAKDVDWASVAAS 5wvb A 3.10 BS02 NAG A 2 W176 L217 Y218 D286 W291 W86 L127 Y128 D196 W201 3.2.1.14 U5LUV7 DGYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLDIDWLYPKGGDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAPKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGAYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGNVKYPLIGAMREELRGISRGKDAKDVDWASVAAS 5wvb A 3.10 BS03 NAG A 3 Y98 G175 W176 D215 L217 M283 Y285 D286 Y340 R342 W433 Y8 G85 W86 D125 L127 M193 Y195 D196 Y250 R252 W343 3.2.1.14 U5LUV7 DGYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLDIDWLYPKGGDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAPKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGAYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGNVKYPLIGAMREELRGISRGKDAKDVDWASVAAS 5wvb A 3.10 BS04 NAG A 4 F129 W176 S177 E370 F373 W433 M437 F39 W86 S87 E280 F283 W343 M347 3.2.1.14 U5LUV7 DGYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTGLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLDIDWLYPKGGDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAPKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGAYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGNVKYPLIGAMREELRGISRGKDAKDVDWASVAAS 5wvg A 2.69 BS01 NAG A 1 W538 A607 T798 E800 W11 A80 T271 E273 3.2.1.14 U5LUV7 EPQVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVALREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWLYPRGADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIGMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGSCGTGKYPLITAMKQELSGYKVKL 5wvg A 2.69 BS02 NAG A 2 W538 W606 A607 E800 F803 W864 M868 W11 W79 A80 E273 F276 W337 M341 3.2.1.14 U5LUV7 EPQVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVALREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWLYPRGADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIGMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGSCGTGKYPLITAMKQELSGYKVKL 5wvg A 2.69 BS03 NAG A 3 F565 G605 W606 D645 L647 A686 M713 Y715 D716 Y770 R772 W864 F38 G78 W79 D118 L120 A159 M186 Y188 D189 Y243 R245 W337 3.2.1.14 U5LUV7 EPQVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVALREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWLYPRGADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIGMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGSCGTGKYPLITAMKQELSGYKVKL 5wvg A 2.69 BS04 NAG A 4 W606 L647 Y648 M713 D716 Q720 W721 R772 W79 L120 Y121 M186 D189 Q193 W194 R245 3.2.1.14 U5LUV7 EPQVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVALREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWLYPRGADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIGMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGSCGTGKYPLITAMKQELSGYKVKL 5wvg A 2.69 BS05 NAG A 5 W606 Y648 D716 W721 W79 Y121 D189 W194 3.2.1.14 U5LUV7 EPQVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVALREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWLYPRGADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIGMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGSCGTGKYPLITAMKQELSGYKVKL 5wvg A 2.69 BS06 NAG A 6 N778 T780 Q781 N251 T253 Q254 3.2.1.14 U5LUV7 EPQVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVALREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWLYPRGADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIGMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGSCGTGKYPLITAMKQELSGYKVKL 5wvh A 2.80 BS01 NAG A 1 W538 W606 A607 E800 F803 W864 W11 W79 A80 E273 F276 W337 3.2.1.14 U5LUV7 EPQVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVALREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWEYPRGADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIGMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGSCGTGKYPLITAMKQELSGYKVKL 5wvh A 2.80 BS02 NAG A 2 Y534 F565 W606 D645 E647 A686 M713 Y715 D716 R772 W864 Y7 F38 W79 D118 E120 A159 M186 Y188 D189 R245 W337 3.2.1.14 U5LUV7 EPQVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVALREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWEYPRGADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMIGMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNEQMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRGSCGTGKYPLITAMKQELSGYKVKL 5wys A 3.00 BS01 7V6 A 1 R218 N229 F247 T251 Y255 E311 A313 G315 G316 R337 G341 T343 T346 S347 A348 R214 N225 F243 T247 Y251 E307 A309 G311 G312 R333 G337 T339 T342 S343 A344 1.13.12.7 P08659 28492074 DAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAK 5x5o A 1.87 BS01 7Z0 A 1 A43 K45 A54 L57 I66 F68 I80 T82 E83 Y84 A85 G88 V140 C150 D151 F152 G153 H158 A36 K38 A47 L50 I59 F61 I73 T75 E76 Y77 A78 G81 V133 C143 D144 F145 G146 H151 2.7.11.25 Q9NYL2 28586211 FVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLER 5xnd A BS01 CA A 1 D52 D54 K55 S56 F58 E63 D53 D55 K56 S57 F59 E64 P59747 29215073 SMAFASVLKDAEVTAALDGCKAAGSFDHKKFFKACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGDGKIGIDEFAAMIKG 5xnd A BS02 CA A 2 D91 D93 D95 K97 I98 G99 E102 D92 D94 D96 K98 I99 G100 E103 P59747 29215073 SMAFASVLKDAEVTAALDGCKAAGSFDHKKFFKACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGDGKIGIDEFAAMIKG 5xts A 2.00 BS01 CA A 1 E452 S454 E461 D475 E422 S424 E431 D445 P22897 29225077 TRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKS 5xtw A 3.20 BS01 CA A 1 E452 S454 E461 D475 E406 S408 E415 D429 P22897 29225077 RQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMK 5xtw C 3.20 BS01 CA C 1 E452 S454 E461 D475 E407 S409 E413 D427 P22897 29225077 TRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENEDCVVMKGKDGYWADRGCEWPLGYICKMK 5xtw D 3.20 BS01 CA D 1 E452 S454 E461 D475 E406 S408 E415 D429 P22897 29225077 RQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMK 5xtw E 3.20 BS01 CA E 1 E452 S454 E461 D475 E407 S409 E416 D430 P22897 29225077 TRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMK 5xtw F 3.20 BS01 CA F 1 E452 S454 E461 D475 E407 S409 E414 D428 P22897 29225077 TRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHERQEDCVVMKGKDGYWADRGCEWPLGYICKMK 5xtw H 3.20 BS01 CA H 1 E452 S454 E461 D475 E407 S409 E413 D427 P22897 29225077 TRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHEQEDCVVMKGKDGYWADRGCEWPLGYICKMK 5xxk A 1.66 BS01 III C 1 Q18 I19 Q24 L54 F55 L57 G58 I61 Y67 Q72 H73 F86 V93 K94 H96 I99 Y100 Q1 I2 Q7 L37 F38 L40 G41 I44 Y50 Q55 H56 F69 V76 K77 H79 I82 Y83 2.3.2.27 Q00987 29228061 QIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIATKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQ 5xxk B 1.66 BS01 III D 1 Q18 I19 Q24 L54 F55 L57 G58 I61 Y67 Q72 H73 F86 V93 K94 H96 I99 Q1 I2 Q7 L37 F38 L40 G41 I44 Y50 Q55 H56 F69 V76 K77 H79 I82 2.3.2.27 Q00987 29228061 QIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIATKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVN 5y2v A 2.60 BS01 AKG D 1 K104 S224 N225 E226 K106 S226 N227 E228 P73862 HHMQATLHQLKVFEATARHGSFTRAAEELYITQPTVSSQIKQLSKTVGLPLFEQIGKRLYLTEAGQELLVTCQDIFQRLDNFAMKVADIKGTKQGRLRLAVITTAKYFIPRLLGEFIQKYPGIEVSLKVTNHEQIRHRMQNNEDDLYIVSEPPEEIDLNYQPFLDNPLVVIARRDHPLAGKSNIPITALNDEAFIMREKGSGTRLAVQNLFHRHYVDVRVRLELGSNEAIKQAIAGGMGISVLSQHTLVSEGARSELTILDIDEFPIKRRWYVANLAGKQLSVITQTFLDYLMAVTKNMPAPFA 5y2v B 2.60 BS01 AKG B 1 K104 S224 N225 E226 K106 S226 N227 E228 P73862 HHMQATLHQLKVFEATARHGSFTRAAEELYITQPTVSSQIKQLSKTVGLPLFEQIGKRLYLTEAGQELLVTCQDIFQRLDNFAMKVADIKGTKQGRLRLAVITTAKYFIPRLLGEFIQKYPGIEVSLKVTNHEQIRHRMQNNEDDLYIVSEPPEEIDLNYQPFLDNPLVVIARRDHPLAGKSNIPITALNDEAFIMREKGSGTRLAVQNLFHRHYVDVRVRLELGSNEAIKQAIAGGMGISVLSQHTLVSEGARSELTILDIDEFPIKRRWYVANLAGKQLSVITQTFLDYLMAVTKNMPAPF 5y2v C 2.60 BS01 AKG B 1 K104 S224 N225 E226 K105 S225 N226 E227 P73862 HMQATLHQLKVFEATARHGSFTRAAEELYITQPTVSSQIKQLSKTVGLPLFEQIGKRLYLTEAGQELLVTCQDIFQRLDNFAMKVADIKGTKQGRLRLAVITTAKYFIPRLLGEFIQKYPGIEVSLKVTNHEQIRHRMQNNEDDLYIVSEPPEEIDLNYQPFLDNPLVVIARRDHPLAGKSNIPITALNDEAFIMREKGSGTRLAVQNLFHRHYVDVRVRLELGSNEAIKQAIAGGMGISVLSQHTLVSEGARSELTILDIDEFPIKRRWYVANLAGKQLSVITQTFLDYLMAVTKNMP 5y2v D 2.60 BS01 AKG D 1 K104 S224 N225 E226 K105 S225 N226 E227 P73862 HMQATLHQLKVFEATARHGSFTRAAEELYITQPTVSSQIKQLSKTVGLPLFEQIGKRLYLTEAGQELLVTCQDIFQRLDNFAMKVADIKGTKQGRLRLAVITTAKYFIPRLLGEFIQKYPGIEVSLKVTNHEQIRHRMQNNEDDLYIVSEPPEEIDLNYQPFLDNPLVVIARRDHPLAGKSNIPITALNDEAFIMREKGSGTRLAVQNLFHRHYVDVRVRLELGSNEAIKQAIAGGMGISVLSQHTLVSEGARSELTILDIDEFPIKRRWYVANLAGKQLSVITQTFLDYLMAVTKNMPAPF 5y2w A 2.20 BS01 PGA A 1 I100 T101 T102 N129 H130 N164 R195 S199 G200 T201 R267 I9 T10 T11 N38 H39 N73 R104 S108 G109 T110 R176 P73862 QGRLRLAVITTAKYFIPRLLGEFIQKYPGIEVSLKVTNHEQIRHRMQNNEDDLYIVSEPPEEIDLNYQPFLDNPLVVIARRDHPLAGKSNIPITALNDEAFIMREKGSGTRLAVQNLFHRHYVDVRVRLELGSNEAIKQAIAGGMGISVLSQHTLVSEGARSELTILDIDEFPIKRRWYVANLAGKQLSVITQTFLDYLMAVTKNMPA 5y66 A 2.34 BS01 FAD A 1 I13 G14 A15 G16 L17 A18 E37 R38 R39 L55 A56 R111 L133 G134 L135 A165 D166 G167 Y193 G310 D311 P318 G321 Q322 G323 M324 N325 I6 G7 A8 G9 L10 A11 E30 R31 R32 L48 A49 R104 L126 G127 L128 A158 D159 G160 Y186 G303 D304 P311 G314 Q315 G316 M317 N318 1.14.13.9 Q84HF5 29208702 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGASIHFNLGLDSVDFARQRLTLSNVSGERLEKRFHLLIGADGCNSAVRQAMASVVDLGEHLETQPHGYKELQITPEASAQFNLEPNALHIWPHGDYMCIALPNLDRSFTVTLFLHHQSPAAQPASPCFAQLVDGHAARRFFQRQFPDLSPMLDSLEQDFEHHPTGKLATLRLTTWHVGGQAVLLGDAAHPMVPFHGQGMNCALEDAVALAEHLQSAADNASALAAFTAQRQPDALAIQAMALENYVEMSSKVASPTYLLERELGQIMAQRQPTRFIPRYSMVTFSRLPYAQAMARGQIQEQLLKFAVANHSDLTSINLDAVEHEVTRCLPP 5y66 A 2.34 BS02 7ZR A 1 R84 E372 Y382 E385 R386 G389 P402 R403 Y404 Q424 E425 L428 R77 E365 Y375 E378 R379 G382 P395 R396 Y397 Q417 E418 L421 1.14.13.9 Q84HF5 29208702 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGASIHFNLGLDSVDFARQRLTLSNVSGERLEKRFHLLIGADGCNSAVRQAMASVVDLGEHLETQPHGYKELQITPEASAQFNLEPNALHIWPHGDYMCIALPNLDRSFTVTLFLHHQSPAAQPASPCFAQLVDGHAARRFFQRQFPDLSPMLDSLEQDFEHHPTGKLATLRLTTWHVGGQAVLLGDAAHPMVPFHGQGMNCALEDAVALAEHLQSAADNASALAAFTAQRQPDALAIQAMALENYVEMSSKVASPTYLLERELGQIMAQRQPTRFIPRYSMVTFSRLPYAQAMARGQIQEQLLKFAVANHSDLTSINLDAVEHEVTRCLPP 5y66 A 2.34 BS03 KYN A 1 A56 R84 L213 L226 F238 P318 F319 H320 G321 N369 M373 Y404 A49 R77 L206 L219 F231 P311 F312 H313 G314 N362 M366 Y397 1.14.13.9 Q84HF5 29208702 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGASIHFNLGLDSVDFARQRLTLSNVSGERLEKRFHLLIGADGCNSAVRQAMASVVDLGEHLETQPHGYKELQITPEASAQFNLEPNALHIWPHGDYMCIALPNLDRSFTVTLFLHHQSPAAQPASPCFAQLVDGHAARRFFQRQFPDLSPMLDSLEQDFEHHPTGKLATLRLTTWHVGGQAVLLGDAAHPMVPFHGQGMNCALEDAVALAEHLQSAADNASALAAFTAQRQPDALAIQAMALENYVEMSSKVASPTYLLERELGQIMAQRQPTRFIPRYSMVTFSRLPYAQAMARGQIQEQLLKFAVANHSDLTSINLDAVEHEVTRCLPP 5y6z A 2.50 BS01 NUC B 1 P20 R22 L43 E108 T114 S115 K126 K127 Y157 K159 D160 I176 A178 S179 R188 H199 V210 G211 C212 N213 S289 G290 C291 S292 G293 T294 Y327 D413 R416 L420 P20 R22 L43 E108 T114 S115 K126 K127 Y157 K159 D160 I176 A178 S179 R188 H199 V210 G211 C212 N213 S289 G290 C291 S292 G293 T294 Y327 D408 R411 L415 L7WS61 29164396 GEIQWMKSNKETGRLNINGPTRTKLEPSAFYDVFEGSKKPAVLTSKDPRLEVDFEQALFSKYVGNTLHEPDEYVTQAALHYANQLKQLDINVNKMSMEEACYGTEYLEAIDLHTSAGYPYSALGVKKRDILDPITRDTTKMKFYMDKYGLDLPYSTYVKDELRSLDKIRKGKSRLIEASSLNDSVYLRMTFGHLYETFHANPGTVTGSAVGCNPDVFWSKLPILLPGSLFAFDYSGYDASLSPVWFRALEVVLREIGYPEEAVSLIEGINHTHHVYRNRTYCVLGGMPSGCSGTSIFNSMINNIIIRTLLIKTFKGIDLDELHMVAYGDDVLASYPFPIDCLELAKTGKEYGLTMTPCFNEVTWENATFLKRGFLPDHQFPFLIHPTMPMREIHESIRWTKDARNTQDHVRSLCLLAWHNGKEEYEKFVSTIRSVPIGRALAIPNYENLRRNWLELF 5y6z A 2.50 BS02 NUC C 1 H113 S295 Y327 G328 D329 L375 K376 R377 M393 S401 K406 N410 D413 H414 S417 H113 S295 Y327 G328 D329 L370 K371 R372 M388 S396 K401 N405 D408 H409 S412 L7WS61 29164396 GEIQWMKSNKETGRLNINGPTRTKLEPSAFYDVFEGSKKPAVLTSKDPRLEVDFEQALFSKYVGNTLHEPDEYVTQAALHYANQLKQLDINVNKMSMEEACYGTEYLEAIDLHTSAGYPYSALGVKKRDILDPITRDTTKMKFYMDKYGLDLPYSTYVKDELRSLDKIRKGKSRLIEASSLNDSVYLRMTFGHLYETFHANPGTVTGSAVGCNPDVFWSKLPILLPGSLFAFDYSGYDASLSPVWFRALEVVLREIGYPEEAVSLIEGINHTHHVYRNRTYCVLGGMPSGCSGTSIFNSMINNIIIRTLLIKTFKGIDLDELHMVAYGDDVLASYPFPIDCLELAKTGKEYGLTMTPCFNEVTWENATFLKRGFLPDHQFPFLIHPTMPMREIHESIRWTKDARNTQDHVRSLCLLAWHNGKEEYEKFVSTIRSVPIGRALAIPNYENLRRNWLELF 5y6z E 2.50 BS01 NUC F 1 N18 G19 P20 L43 E108 T114 S115 S121 K127 Y157 K159 D160 I176 A178 S179 R188 H199 G211 C212 N213 S289 G290 C291 S292 G293 T294 Y327 D413 R416 L420 N18 G19 P20 L43 E108 T114 S115 S121 K127 Y157 K159 D160 I176 A178 S179 R188 H199 G211 C212 N213 S289 G290 C291 S292 G293 T294 Y327 D411 R414 L418 L7WS61 29164396 GEIQWMKSNKETGRLNINGPTRTKLEPSAFYDVFEGSKKPAVLTSKDPRLEVDFEQALFSKYVGNTLHEPDEYVTQAALHYANQLKQLDINVNKMSMEEACYGTEYLEAIDLHTSAGYPYSALGVKKRDILDPITRDTTKMKFYMDKYGLDLPYSTYVKDELRSLDKIRKGKSRLIEASSLNDSVYLRMTFGHLYETFHANPGTVTGSAVGCNPDVFWSKLPILLPGSLFAFDYSGYDASLSPVWFRALEVVLREIGYPEEAVSLIEGINHTHHVYRNRTYCVLGGMPSGCSGTSIFNSMINNIIIRTLLIKTFKGIDLDELHMVAYGDDVLASYPFPIDCLELAKTGKEYGLTMTPKSPCFNEVTWENATFLKRGFLPDHQFPFLIHPTMPMREIHESIRWTKDARNTQDHVRSLCLLAWHNGKEEYEKFVSTIRSVPIGRALAIPNYENLRRNWLELF 5y6z E 2.50 BS02 NUC G 1 H113 Y327 G328 D329 D330 L375 K376 R377 E397 S401 N410 D413 H414 S417 H113 Y327 G328 D329 D330 L373 K374 R375 E395 S399 N408 D411 H412 S415 L7WS61 29164396 GEIQWMKSNKETGRLNINGPTRTKLEPSAFYDVFEGSKKPAVLTSKDPRLEVDFEQALFSKYVGNTLHEPDEYVTQAALHYANQLKQLDINVNKMSMEEACYGTEYLEAIDLHTSAGYPYSALGVKKRDILDPITRDTTKMKFYMDKYGLDLPYSTYVKDELRSLDKIRKGKSRLIEASSLNDSVYLRMTFGHLYETFHANPGTVTGSAVGCNPDVFWSKLPILLPGSLFAFDYSGYDASLSPVWFRALEVVLREIGYPEEAVSLIEGINHTHHVYRNRTYCVLGGMPSGCSGTSIFNSMINNIIIRTLLIKTFKGIDLDELHMVAYGDDVLASYPFPIDCLELAKTGKEYGLTMTPKSPCFNEVTWENATFLKRGFLPDHQFPFLIHPTMPMREIHESIRWTKDARNTQDHVRSLCLLAWHNGKEEYEKFVSTIRSVPIGRALAIPNYENLRRNWLELF 5y6z E 2.50 BS03 MG E 1 D233 D330 D233 D330 L7WS61 29164396 GEIQWMKSNKETGRLNINGPTRTKLEPSAFYDVFEGSKKPAVLTSKDPRLEVDFEQALFSKYVGNTLHEPDEYVTQAALHYANQLKQLDINVNKMSMEEACYGTEYLEAIDLHTSAGYPYSALGVKKRDILDPITRDTTKMKFYMDKYGLDLPYSTYVKDELRSLDKIRKGKSRLIEASSLNDSVYLRMTFGHLYETFHANPGTVTGSAVGCNPDVFWSKLPILLPGSLFAFDYSGYDASLSPVWFRALEVVLREIGYPEEAVSLIEGINHTHHVYRNRTYCVLGGMPSGCSGTSIFNSMINNIIIRTLLIKTFKGIDLDELHMVAYGDDVLASYPFPIDCLELAKTGKEYGLTMTPKSPCFNEVTWENATFLKRGFLPDHQFPFLIHPTMPMREIHESIRWTKDARNTQDHVRSLCLLAWHNGKEEYEKFVSTIRSVPIGRALAIPNYENLRRNWLELF 5y77 A 1.60 BS01 FAD A 1 I13 G14 A15 G16 L17 A18 E37 R38 R39 L55 A56 R111 L133 G134 L135 A165 D166 G167 A171 Y193 G310 D311 P318 G321 Q322 G323 M324 N325 I7 G8 A9 G10 L11 A12 E31 R32 R33 L49 A50 R105 L127 G128 L129 A159 D160 G161 A165 Y187 G304 D305 P312 G315 Q316 G317 M318 N319 1.14.13.9 Q84HF5 29208702 ARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGASIHFNLGLDSVDFARQRLTLSNVSGERLEKRFHLLIGADGCNSAVRQAMASVVDLGEHLETQPHGYKELQITPEASAQFNLEPNALHIWPHGDYMCIALPNLDRSFTVTLFLHHQSPAAQPASPCFAQLVDGHAARRFFQRQFPDLSPMLDSLEQDFEHHPTGKLATLRLTTWHVGGQAVLLGDAAHPMVPFHGQGMNCALEDAVALAEHLQSAADNASALAAFTAQRQPDALAIQAMALENYVEMSSKVASPTYLLERELGQIMAQRQPTRFIPRYSMVTFSRLPYAQAMARGQIQEQLLKFAVANHSDLTSINLDAVEHEVTRCLPPLSHLC 5y77 A 1.60 BS02 KYN A 1 A56 R84 Y98 I106 L213 I224 L226 P318 F319 H320 G321 N369 M373 Y404 A50 R78 Y92 I100 L207 I218 L220 P312 F313 H314 G315 N363 M367 Y398 1.14.13.9 Q84HF5 29208702 ARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGASIHFNLGLDSVDFARQRLTLSNVSGERLEKRFHLLIGADGCNSAVRQAMASVVDLGEHLETQPHGYKELQITPEASAQFNLEPNALHIWPHGDYMCIALPNLDRSFTVTLFLHHQSPAAQPASPCFAQLVDGHAARRFFQRQFPDLSPMLDSLEQDFEHHPTGKLATLRLTTWHVGGQAVLLGDAAHPMVPFHGQGMNCALEDAVALAEHLQSAADNASALAAFTAQRQPDALAIQAMALENYVEMSSKVASPTYLLERELGQIMAQRQPTRFIPRYSMVTFSRLPYAQAMARGQIQEQLLKFAVANHSDLTSINLDAVEHEVTRCLPPLSHLC 5y77 B 1.60 BS01 FAD B 1 I13 G14 A15 G16 L17 A18 E37 R38 R39 L55 A56 R111 G134 L135 A165 D166 G167 A171 Y193 G310 D311 G321 Q322 G323 M324 N325 I6 G7 A8 G9 L10 A11 E30 R31 R32 L48 A49 R104 G127 L128 A158 D159 G160 A164 Y186 G303 D304 G314 Q315 G316 M317 N318 1.14.13.9 Q84HF5 29208702 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGASIHFNLGLDSVDFARQRLTLSNVSGERLEKRFHLLIGADGCNSAVRQAMASVVDLGEHLETQPHGYKELQITPEASAQFNLEPNALHIWPHGDYMCIALPNLDRSFTVTLFLHHQSPAAQPASPCFAQLVDGHAARRFFQRQFPDLSPMLDSLEQDFEHHPTGKLATLRLTTWHVGGQAVLLGDAAHPMVPFHGQGMNCALEDAVALAEHLQSAADNASALAAFTAQRQPDALAIQAMALENYVEMSSKVASPTYLLERELGQIMAQRQPTRFIPRYSMVTFSRLPYAQAMARGQIQEQLLKFAVANHSDLTSINLDAVEHEVTRCLPPLS 5y77 B 1.60 BS02 KYN B 1 A56 R84 Y98 I106 L213 I224 L226 P318 F319 H320 N369 M373 Y404 A49 R77 Y91 I99 L206 I217 L219 P311 F312 H313 N362 M366 Y397 1.14.13.9 Q84HF5 29208702 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGASIHFNLGLDSVDFARQRLTLSNVSGERLEKRFHLLIGADGCNSAVRQAMASVVDLGEHLETQPHGYKELQITPEASAQFNLEPNALHIWPHGDYMCIALPNLDRSFTVTLFLHHQSPAAQPASPCFAQLVDGHAARRFFQRQFPDLSPMLDSLEQDFEHHPTGKLATLRLTTWHVGGQAVLLGDAAHPMVPFHGQGMNCALEDAVALAEHLQSAADNASALAAFTAQRQPDALAIQAMALENYVEMSSKVASPTYLLERELGQIMAQRQPTRFIPRYSMVTFSRLPYAQAMARGQIQEQLLKFAVANHSDLTSINLDAVEHEVTRCLPPLS 5y7a A 1.85 BS01 FAD A 1 I13 G14 G16 L17 A18 E37 R38 L55 A56 R111 L133 G134 L135 A165 D166 G167 Y193 G310 D311 P318 G321 Q322 G323 M324 N325 I7 G8 G10 L11 A12 E31 R32 L49 A50 R105 L127 G128 L129 A159 D160 G161 Y187 G304 D305 P312 G315 Q316 G317 M318 N319 1.14.13.9 Q84HF5 29208702 ARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGASIHFNLGLDSVDFARQRLTLSNVSGERLEKRFHLLIGADGCNSAVRQAMASVVDLGEHLETQPHGYKELQITPEASAQFNLEPNALHIWPHGDYMCIALPNLDRSFTVTLFLHHQSPAAQPASPCFAQLVDGHAARRFFQRQFPDLSPMLDSLEQDFEHHPTGKLATLRLTTWHVGGQAVLLGDAAHPMVPFHGQGMNCALEDAVALAEHLQSAADNASALAAFTAQRQPDALAIQAMALENYVEMSSKVASPTYLLERELGQIMAQRQPTRFIPRYSMVTFSRLPYAQAMARGQIQEQLLKFAVANHSDLTSINLDAVEHEVTRCLPPL 5y7a A 1.85 BS02 KYN A 1 A56 L213 I224 L226 F238 P318 F319 H320 N369 M373 Y404 A50 L207 I218 L220 F232 P312 F313 H314 N363 M367 Y398 1.14.13.9 Q84HF5 29208702 ARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLAGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGASIHFNLGLDSVDFARQRLTLSNVSGERLEKRFHLLIGADGCNSAVRQAMASVVDLGEHLETQPHGYKELQITPEASAQFNLEPNALHIWPHGDYMCIALPNLDRSFTVTLFLHHQSPAAQPASPCFAQLVDGHAARRFFQRQFPDLSPMLDSLEQDFEHHPTGKLATLRLTTWHVGGQAVLLGDAAHPMVPFHGQGMNCALEDAVALAEHLQSAADNASALAAFTAQRQPDALAIQAMALENYVEMSSKVASPTYLLERELGQIMAQRQPTRFIPRYSMVTFSRLPYAQAMARGQIQEQLLKFAVANHSDLTSINLDAVEHEVTRCLPPL 5yjm A 1.90 BS01 ZN A 1 H25 E77 H10 E64 29191554 IIGGTESKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 5yjm A 1.90 BS02 8W3 A 1 F41 C42 H57 Y94 L99 D102 R143 A190 F191 K192 G193 S195 V213 S214 Y215 G216 R217 S218 A226 F29 C30 H45 Y81 L86 D89 R122 A169 F170 K171 G172 S174 V188 S189 Y190 G191 R192 S193 A199 29191554 IIGGTESKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 5yjp A 1.80 BS01 ZN A 1 H25 E77 H10 E64 29191554 IIGGTESKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 5yjp A 1.80 BS02 8W6 A 1 F41 C42 H57 D102 R143 A190 F191 K192 G193 S195 V213 S214 G216 R217 S218 A226 F29 C30 H45 D89 R124 A171 F172 K173 G174 S176 V190 S191 G193 R194 S195 A201 29191554 IIGGTESKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN 5ykn A 2.30 BS01 ZN A 1 C519 C522 C542 H545 C409 C412 C432 H435 1.14.11.- Q8GUI6 29233856 RWNPSEACRPLVDDAPIFYPTNEDFDDPLGYIEKLRSKAESYGICRIVPPVAWRPPCPLKEKKIWENSKFPTRIQFIDLLQNRFGFQTGPDFTLAAFQKYDEYFKECYFQPKVKDLEGEYWRIVEQATDEVEVYYGADLETKKFGSGFPKYKPGYPISEADQYSQCGWNLNNLSRLPGSVLAFESCDISGVIVPWLYVGMCFSTFCWHVEDHHLYSMNYLHTGDPKVWYGIPGNHAESFENVMKKRLPDLFEEQPDLLHQLVTQLSPRILKEEGVPVYRAVQRSGEFILTFPKAYHSGFNCGFNCAEAVNVAPVDWLVHGQNAVEGYSKQRRKSSLSHDKLLLGAAMEATYCLWELSLSKKKTPVIARWKRVCSEDGLLTKAVKKRVQMEEERLNHLQDGFSLRKMRECFLCFYDLHMSASSCKCSPNRFACLIHAKDLCSCESKDRYILIRHTLDELWALVRALEGDLDAIDLWASK 5ykn A 2.30 BS02 ZN A 2 C533 C535 C550 C552 C423 C425 C440 C442 1.14.11.- Q8GUI6 29233856 RWNPSEACRPLVDDAPIFYPTNEDFDDPLGYIEKLRSKAESYGICRIVPPVAWRPPCPLKEKKIWENSKFPTRIQFIDLLQNRFGFQTGPDFTLAAFQKYDEYFKECYFQPKVKDLEGEYWRIVEQATDEVEVYYGADLETKKFGSGFPKYKPGYPISEADQYSQCGWNLNNLSRLPGSVLAFESCDISGVIVPWLYVGMCFSTFCWHVEDHHLYSMNYLHTGDPKVWYGIPGNHAESFENVMKKRLPDLFEEQPDLLHQLVTQLSPRILKEEGVPVYRAVQRSGEFILTFPKAYHSGFNCGFNCAEAVNVAPVDWLVHGQNAVEGYSKQRRKSSLSHDKLLLGAAMEATYCLWELSLSKKKTPVIARWKRVCSEDGLLTKAVKKRVQMEEERLNHLQDGFSLRKMRECFLCFYDLHMSASSCKCSPNRFACLIHAKDLCSCESKDRYILIRHTLDELWALVRALEGDLDAIDLWASK 5yko A 2.90 BS01 III P 1 D239 S290 G291 W296 Y298 H309 E311 D312 S317 Q361 L362 A409 V410 N411 S436 E516 D138 S189 G190 W195 Y197 H208 E210 D211 S216 Q260 L261 A308 V309 N310 S335 E415 1.14.11.- Q8GUI6 29233856 RWNPSEACRPLVDDAPIFYPTNEDFDDPLGYIEKLRSKAESYGICRIVPPVAWRPPCPLKEKKIWENSKFPTRIQFIDLLQNRFGFQTGPDFTLAAFQKYDEYFKECYFQPKVKDLEGEYWRIVEQATDEVEVYYGADLETKKFGSGFPKYKPGYPISEADQYSQCGWNLNNLSRLPGSVLAFESCDISGVIVPWLYVGMCFSTFCWHVEDHHLYSMNYLHTGDPKVWYGIPGNHAESFENVMKKRLPDLFEEQPDLLHQLVTQLSPRILKEEGVPVYRAVQRSGEFILTFPKAYHSGFNCGFNCAEAVNVAPVDWLVHGQNAVEGYSKQRRKSSLSHDKLLLGAAMEATYCLWELSLSKKKTPVIARWKRVCSEDGLLTKAVKKRVQMEEERLNHLQDGFSLRKMEGDFDNKRERECFLCFYDLHMSASSCKCSPNRFACLIHAKDLCSCESKDRYILIRHTLDELWALVRALEGDLDAIDLWASK 5yko A 2.90 BS02 ZN A 1 C519 C522 C542 H545 C418 C421 C441 H444 1.14.11.- Q8GUI6 29233856 RWNPSEACRPLVDDAPIFYPTNEDFDDPLGYIEKLRSKAESYGICRIVPPVAWRPPCPLKEKKIWENSKFPTRIQFIDLLQNRFGFQTGPDFTLAAFQKYDEYFKECYFQPKVKDLEGEYWRIVEQATDEVEVYYGADLETKKFGSGFPKYKPGYPISEADQYSQCGWNLNNLSRLPGSVLAFESCDISGVIVPWLYVGMCFSTFCWHVEDHHLYSMNYLHTGDPKVWYGIPGNHAESFENVMKKRLPDLFEEQPDLLHQLVTQLSPRILKEEGVPVYRAVQRSGEFILTFPKAYHSGFNCGFNCAEAVNVAPVDWLVHGQNAVEGYSKQRRKSSLSHDKLLLGAAMEATYCLWELSLSKKKTPVIARWKRVCSEDGLLTKAVKKRVQMEEERLNHLQDGFSLRKMEGDFDNKRERECFLCFYDLHMSASSCKCSPNRFACLIHAKDLCSCESKDRYILIRHTLDELWALVRALEGDLDAIDLWASK 5yko A 2.90 BS03 ZN A 2 C533 C535 C550 C552 C432 C434 C449 C451 1.14.11.- Q8GUI6 29233856 RWNPSEACRPLVDDAPIFYPTNEDFDDPLGYIEKLRSKAESYGICRIVPPVAWRPPCPLKEKKIWENSKFPTRIQFIDLLQNRFGFQTGPDFTLAAFQKYDEYFKECYFQPKVKDLEGEYWRIVEQATDEVEVYYGADLETKKFGSGFPKYKPGYPISEADQYSQCGWNLNNLSRLPGSVLAFESCDISGVIVPWLYVGMCFSTFCWHVEDHHLYSMNYLHTGDPKVWYGIPGNHAESFENVMKKRLPDLFEEQPDLLHQLVTQLSPRILKEEGVPVYRAVQRSGEFILTFPKAYHSGFNCGFNCAEAVNVAPVDWLVHGQNAVEGYSKQRRKSSLSHDKLLLGAAMEATYCLWELSLSKKKTPVIARWKRVCSEDGLLTKAVKKRVQMEEERLNHLQDGFSLRKMEGDFDNKRERECFLCFYDLHMSASSCKCSPNRFACLIHAKDLCSCESKDRYILIRHTLDELWALVRALEGDLDAIDLWASK 5yl3 A 1.50 BS01 HNN A 1 F43 K45 H64 V67 V68 L89 S92 H93 H97 I99 Y103 I107 F138 F43 K45 H64 V67 V68 L89 S92 H93 H97 I99 Y103 I107 F138 P68082 29237270 GLSDGEWQQVLNVWGKVEADIAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGTVVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLHSKHPGDFGADAQGAMTKALELFRNDIAAKYKELGF 5yob A 1.14 BS01 FMN A 1 S10 T11 T12 G13 N14 T15 S58 T59 W60 G61 C93 G94 D95 W98 Y100 F101 C102 S10 T11 T12 G13 N14 T15 S58 T59 W60 G61 C93 G94 D95 W98 Y100 F101 C102 P00323 29039033 SAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFEGFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSWEYFCGAVDAIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAI 5yoc A 1.50 BS01 FMN A 1 S10 T11 T12 G13 N14 T15 S58 T59 W60 G61 D62 C93 G94 D95 W98 Y100 F101 C102 S10 T11 T12 G13 N14 T15 S58 T59 W60 G61 D62 C93 G94 D95 W98 Y100 F101 C102 P00323 29039033 SAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFEGFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSWEYFCGAVDAIEEKLKNLGAEIVQDGLCIDGDPRAARDDIVGWAHDVRGAI 5yoe A 1.35 BS01 FMN A 1 S10 T11 T12 G13 N14 T15 S58 T59 W60 G61 D62 C93 G94 D95 W98 Y100 F101 C102 S10 T11 T12 G13 N14 T15 S58 T59 W60 G61 D62 C93 G94 D95 W98 Y100 F101 C102 P00323 29039033 SAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVECGGLFEGFDLVLLGCSTWGDDSIELQDDFIPCFDSLEETGAQGRKVACFGCGDSSWEYFCGAVDAIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAI 5ytk A 2.70 BS01 III G 1 V292 F294 G295 E296 P297 L298 V172 F174 G175 E176 P177 L178 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk A 2.70 BS02 ZN A 1 C256 C259 C280 C283 C136 C139 C160 C163 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk A 2.70 BS03 LEU G 1 F157 F180 Q228 H248 F294 F37 F60 Q108 H128 F174 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk B 2.70 BS01 ZN B 1 C256 C259 C280 C283 C136 C139 C160 C163 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk B 2.70 BS02 LEU B 1 F157 R158 F180 H248 F294 F37 R38 F60 H128 F174 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk B 2.70 BS03 LYS B 1 V292 F294 G295 E296 V172 F174 G175 E176 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk C 2.70 BS01 ZN C 1 C256 C259 C280 C283 C135 C138 C159 C162 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk C 2.70 BS02 LEU C 1 F157 F180 Q228 H248 F36 F59 Q107 H127 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk C 2.70 BS03 LYS C 1 V292 F293 G295 E296 V171 F172 G174 E175 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk D 2.70 BS01 III J 1 V292 F294 G295 E296 P297 L298 F302 H305 P326 V172 F174 G175 E176 P177 L178 F182 H185 P206 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk D 2.70 BS02 ZN D 1 C256 C259 C280 C283 C136 C139 C160 C163 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk D 2.70 BS03 LEU J 1 F157 F180 Q228 H248 F294 F37 F60 Q108 H128 F174 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk E 2.70 BS01 III K 1 H248 V292 F293 F294 G295 E296 P297 L298 F302 H305 H128 V172 F173 F174 G175 E176 P177 L178 F182 H185 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk E 2.70 BS02 III L 1 E323 V324 E325 E203 V204 E205 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk E 2.70 BS03 ZN E 1 C256 C259 C280 C283 C136 C139 C160 C163 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk E 2.70 BS04 LEU K 1 F157 F180 Q228 H248 F37 F60 Q108 H128 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk F 2.70 BS01 III L 1 E177 V292 F294 G295 E296 P297 L298 F302 H305 E57 V172 F174 G175 E176 P177 L178 F182 H185 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk F 2.70 BS02 ZN F 1 C256 C259 C280 C283 C136 C139 C160 C163 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5ytk F 2.70 BS03 LEU L 1 F157 F180 Q228 I230 H248 V292 F37 F60 Q108 I110 H128 V172 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5yu9 A 1.95 BS01 1E8 A 1 L718 G719 V726 A743 K745 M766 L788 M790 Q791 M793 C797 R841 L844 T854 D855 F856 L19 G20 V27 A44 K46 M63 L85 M87 Q88 M90 C94 R138 L141 T151 D152 F153 2.7.10.1 P00533 27626175 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYL 5yu9 B 1.95 BS01 1E8 B 1 L718 G719 V726 A743 K745 M766 L788 M790 Q791 M793 C797 R841 L844 T854 D855 F856 L20 G21 V28 A45 K47 M63 L85 M87 Q88 M90 C94 R138 L141 T151 D152 F153 2.7.10.1 P00533 27626175 PNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVV 5yu9 C 1.95 BS01 1E8 C 1 V726 A743 K745 M766 L788 M790 Q791 M793 G796 C797 D800 R841 T854 D855 F856 V30 A47 K49 M66 L88 M90 Q91 M93 G96 C97 D100 R141 T154 D155 F156 2.7.10.1 P00533 27626175 EAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMVDADEYLIPQQ 5yu9 D 1.95 BS01 1E8 D 1 V726 A743 K745 M766 M790 Q791 M793 G796 C797 D800 L844 T854 D855 V27 A44 K46 M67 M91 Q92 M94 G97 C98 D101 L145 T155 D156 2.7.10.1 P00533 27626175 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVD 5yvm A 2.12 BS01 MN A 1 D204 H208 H273 H288 L292 D207 H211 H276 H291 L295 A0A133UP32 29188989 HMRMEFRHNLPSSDIIFGSGTLEKIGEETKKWGDKAILVTGKSNMKKLGFLADAIDYLESAGVETVHYGEIEPNPTTTVVDEGAEIVLEEGCDVVVALGGGSSMDAAKGIAMVAGHSAEERDISVWDFAPEGDKETKPITEKTLPVIAATSTSGTGSHVTPYAVITNPETKGKPGFGNKHSFPKVSIVDIDILKEMPPRLTAITGYDVFSHVSENLTAKGDHPTADPLAIRAIEYVTEYLLRAVEDGEDIKAREKMAVADTYAGLSNTISGTTLRHAMAHPISGYYPDISHGQALASISVPIMEHNIENGDEKTWERYSRIAVALDASKPVDNTRQAASKAVDGLKNLLRSLDLDKPLSELGVEEEKIPEMTEGAFIYMGGGIEANPVDVSKEDVKEIFRKSL 5yvm A 2.12 BS02 NZQ A 1 G38 K39 S40 N41 M42 P70 N71 G97 G98 S99 D102 S148 T149 T152 S154 T157 Y159 V161 K170 I189 E192 M193 P194 L197 T201 H208 H273 H277 H288 G41 K42 S43 N44 M45 P73 N74 G100 G101 S102 D105 S151 T152 T155 S157 T160 Y162 V164 K173 I192 E195 M196 P197 L200 T204 H211 H276 H280 H291 A0A133UP32 29188989 HMRMEFRHNLPSSDIIFGSGTLEKIGEETKKWGDKAILVTGKSNMKKLGFLADAIDYLESAGVETVHYGEIEPNPTTTVVDEGAEIVLEEGCDVVVALGGGSSMDAAKGIAMVAGHSAEERDISVWDFAPEGDKETKPITEKTLPVIAATSTSGTGSHVTPYAVITNPETKGKPGFGNKHSFPKVSIVDIDILKEMPPRLTAITGYDVFSHVSENLTAKGDHPTADPLAIRAIEYVTEYLLRAVEDGEDIKAREKMAVADTYAGLSNTISGTTLRHAMAHPISGYYPDISHGQALASISVPIMEHNIENGDEKTWERYSRIAVALDASKPVDNTRQAASKAVDGLKNLLRSLDLDKPLSELGVEEEKIPEMTEGAFIYMGGGIEANPVDVSKEDVKEIFRKSL 5yvr A 1.90 BS01 MN A 1 D204 H208 H273 H288 L292 D207 H211 H276 H291 L295 A0A133UP32 29188989 HMRMEFRHNLPSSDIIFGSGTLEKIGEETKKWGDKAILVTGKSNMKKLGFLADAIDYLESAGVETVHYGEIEPNPTTTVVDEGAEIVLEEGCDVVVALGGGSSMDAAKGIAMVAGHSAEERDISVWDFAPEGDKETKPITEKTLPVIAATSTSGTGSHVTPYAVITNPETKGKPGFGNKHSFPKVSIVDIDILKEMPPRLTAITGYDVFSHVSENLTAKGDHPTADPLAIRAIEYVTEYLLRAVEDGEDIKAREKMAVADTYAGLSNTISGTTLRHAMAAPISGYYPDISHGQALASISVPIMEHNIENGDEKTWERYSRIAVALDASKPVDNTRQAASKAVDGLKNLLRSLDLDKPLSELGVEEEKIPEMTEGAFIYMGGGIEANPVDVSKEDVKEIFRKSL 5yvr A 1.90 BS02 NDP A 1 G38 K39 S40 N41 M42 L45 P70 N71 P72 G97 G98 S99 D102 S148 T149 T152 T157 Y159 V161 K170 I189 E192 M193 P194 L197 T201 D204 H208 H288 G41 K42 S43 N44 M45 L48 P73 N74 P75 G100 G101 S102 D105 S151 T152 T155 T160 Y162 V164 K173 I192 E195 M196 P197 L200 T204 D207 H211 H291 A0A133UP32 29188989 HMRMEFRHNLPSSDIIFGSGTLEKIGEETKKWGDKAILVTGKSNMKKLGFLADAIDYLESAGVETVHYGEIEPNPTTTVVDEGAEIVLEEGCDVVVALGGGSSMDAAKGIAMVAGHSAEERDISVWDFAPEGDKETKPITEKTLPVIAATSTSGTGSHVTPYAVITNPETKGKPGFGNKHSFPKVSIVDIDILKEMPPRLTAITGYDVFSHVSENLTAKGDHPTADPLAIRAIEYVTEYLLRAVEDGEDIKAREKMAVADTYAGLSNTISGTTLRHAMAAPISGYYPDISHGQALASISVPIMEHNIENGDEKTWERYSRIAVALDASKPVDNTRQAASKAVDGLKNLLRSLDLDKPLSELGVEEEKIPEMTEGAFIYMGGGIEANPVDVSKEDVKEIFRKSL 5yvs A 2.35 BS01 MN A 1 D204 H208 H273 H288 L292 D207 H211 H276 H291 L295 A0A133UP32 29188989 HMRMEFRHNLPSSDIIFGSGTLEKIGEETKKWGDKAILVTGKSNMKKLGFLADAIDYLESAGVETVHYGEIEPNPTTTVVDEGAEIVLEEGCDVVVALGGGSSMDAAKGIAMVAGHSAEERDISVWDFAPEGDKETKPITEKTLPVIAATSTSGTGSHVTPYAVITNPETKGKPGFGNKHSFPKVSIVDIDILKEMPPRLTAITGYDVFSHVSENLTAKGDHPTADPLAIRAIEYVTEYLLRAVEDGEDIKAREKMAVADTYAGLSNTISGTTLRHAMAHPISGYYPDISHGQALASISVPIMEHNIENGDEKTWERYSRIAVALDASKPVDNTRQAASKAVDGLKNLLRSLDLDKPLSELGVEEEKIPEMTEGAFIYMGGGIEANPVDVSKEDVKEIFRKSL 5yvs A 2.35 BS02 NDP A 1 G38 K39 S40 N41 L45 P70 N71 G97 G98 S99 D102 S148 T149 T152 T157 Y159 K170 I189 E192 M193 P194 L197 T201 D204 H208 H288 G41 K42 S43 N44 L48 P73 N74 G100 G101 S102 D105 S151 T152 T155 T160 Y162 K173 I192 E195 M196 P197 L200 T204 D207 H211 H291 A0A133UP32 29188989 HMRMEFRHNLPSSDIIFGSGTLEKIGEETKKWGDKAILVTGKSNMKKLGFLADAIDYLESAGVETVHYGEIEPNPTTTVVDEGAEIVLEEGCDVVVALGGGSSMDAAKGIAMVAGHSAEERDISVWDFAPEGDKETKPITEKTLPVIAATSTSGTGSHVTPYAVITNPETKGKPGFGNKHSFPKVSIVDIDILKEMPPRLTAITGYDVFSHVSENLTAKGDHPTADPLAIRAIEYVTEYLLRAVEDGEDIKAREKMAVADTYAGLSNTISGTTLRHAMAHPISGYYPDISHGQALASISVPIMEHNIENGDEKTWERYSRIAVALDASKPVDNTRQAASKAVDGLKNLLRSLDLDKPLSELGVEEEKIPEMTEGAFIYMGGGIEANPVDVSKEDVKEIFRKSL 6ax1 A 2.26 BS01 C0S A 1 G50 A51 S122 M123 L148 N152 L214 C242 G33 A34 S105 M106 L131 N135 L197 C225 3.1.1.23 Q99685 29148769 DLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATA 6ax1 B 2.26 BS01 C0S B 1 G50 A51 S122 M123 L148 L205 L213 L214 C242 H269 G45 A46 S117 M118 L143 L192 L200 L201 C229 H256 3.1.1.23 Q99685 29148769 SPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLAKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTAT 6ay2 A 1.60 BS01 C1G A 1 Q23 G27 C29 W30 G68 G73 G74 E122 G198 H199 Q24 G28 C30 W31 G69 G74 G75 E123 G199 H200 3.4.22.1 P07858 29227683 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTD 6ay2 B 1.60 BS01 C1G B 1 Q23 G27 C29 W30 G73 G74 P76 E122 G198 H199 Q23 G27 C29 W30 G73 G74 P76 E122 G198 H199 3.4.22.1 P07858 29227683 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTD 6ayd A 3.00 BS01 C2J A 1 F49 A65 K67 E89 L93 L120 E121 R122 L174 I185 D186 F187 F16 A32 K34 E56 L60 L87 E88 R89 L141 I152 D153 F154 2.7.11.1 P11309 29057057 LESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 6azp A 2.29 BS01 CA A 1 D262 T334 F336 D338 S340 D96 T168 F170 D172 S174 1.11.2.2 P05164 CPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 6azr A 3.63 BS01 ANP A 1 E308 N376 N380 G381 K383 Y384 D411 I416 R430 V431 G441 T442 G443 G445 L446 S470 F472 E65 N133 N137 G138 K140 Y141 D168 I173 R187 V188 G195 T196 G197 G199 L200 S224 F226 Q9WZV7 29235472 LKRIDRMKTEFIANISHELRAPLTAIKAYAETIYNSLGELDLSTLKEFLEVIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEFASSHNVNVLFESNVPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKYVKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSYEVPGTGLGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPKDR 6azr B 3.63 BS01 MG B 1 D10 D53 M55 D10 D53 M55 R4NNQ5 29235472 MSKKVLLVDDSAVLRKIVSFNLKKEGYEVIEAENGQIALEKLSEFTPDLIVLDIMMPVMDGFTVLKKLQEKEEWKRIPVIVLTAKGGEEDESLALSLGARKVMRKPFSPSQFIEEVKHLLN 6azr C 3.63 BS01 ANP C 1 E308 N380 G381 K383 Y384 D411 I416 I424 Y429 R430 V431 G441 T442 G443 G445 L446 S470 F472 E65 N137 G138 K140 Y141 D168 I173 I181 Y186 R187 V188 G195 T196 G197 G199 L200 S224 F226 Q9WZV7 29235472 LKRIDRMKTEFIANISHELRAPLTAIKAYAETIYNSLGELDLSTLKEFLEVIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEFASSHNVNVLFESNVPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKYVKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSYEVPGTGLGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPKDR 6azr D 3.63 BS01 MG D 1 D10 D53 M55 D10 D53 M55 R4NNQ5 29235472 MSKKVLLVDDSAVLRKIVSFNLKKEGYEVIEAENGQIALEKLSEFTPDLIVLDIMMPVMDGFTVLKKLQEKEEWKRIPVIVLTAKGGEEDESLALSLGARKVMRKPFSPSQFIEEVKHLLN 6b14 H 1.64 BS01 NUC R 1 Y34 H38 P56 Y57 S58 S60 Y62 Q102 Y104 R105 R106 R110 Y31 H35 P53 Y54 S55 S57 Y59 Q99 Y101 R102 R103 R107 EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVASISPYSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARQGYRRRSGRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6b14 L 1.64 BS01 NUC R 1 S92 F95 N97 S92 F95 N97 SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQSYSFPNTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6b3e A 3.06 BS01 MG A 1 D859 D877 D133 D151 2.7.11.22,2.7.11.23 Q9NYV4 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHW 6b3e A 3.06 BS02 CJM A 1 I733 G734 A754 V787 E814 Y815 M816 H818 D819 S863 L866 A876 I17 G18 A38 V71 E88 Y89 M90 H92 D93 S137 L140 A150 2.7.11.22,2.7.11.23 Q9NYV4 SDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHW 6b3e C 3.06 BS01 MG C 1 D859 D877 D131 D149 2.7.11.22,2.7.11.23 Q9NYV4 WGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHW 6b3e C 3.06 BS02 CJM C 1 I733 G734 A754 V787 F813 E814 Y815 M816 H818 D819 S863 N864 L866 A876 I15 G16 A36 V69 F85 E86 Y87 M88 H90 D91 S135 N136 L138 A148 2.7.11.22,2.7.11.23 Q9NYV4 WGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHW 6b3k H 2.09 BS01 NUC R 1 Y34 H38 S55 P56 Y57 S58 S60 Y62 Q102 Y104 R105 R106 R110 Y31 H35 S52 P53 Y54 S55 S57 Y59 Q99 Y101 R102 R103 R107 EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVASISPYSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARQGYRRRSGRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6b3k H 2.09 BS02 MG L 1 F178 L190 S191 F175 L187 S188 EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVASISPYSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARQGYRRRSGRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6b3k L 2.09 BS01 NUC R 1 S92 F95 S92 F95 SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQSYSFPSTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6b3k L 2.09 BS02 MG L 1 S163 S177 S163 S177 SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQSYSFPSTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6b3w A 3.05 BS01 ZN A 1 C420 H422 C427 C431 C253 H255 C260 C264 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w A 3.05 BS02 ZN A 2 C420 C433 C440 C444 C253 C266 C273 C277 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w A 3.05 BS03 ZN A 3 C427 C440 C446 C450 C260 C273 C279 C283 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w A 3.05 BS04 ZN A 4 C457 C459 C463 C468 C290 C292 C296 C301 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w A 3.05 BS05 ZN A 5 C463 C477 C485 C498 C296 C310 C318 C331 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w A 3.05 BS06 ZN A 6 C457 C470 C477 C482 C290 C303 C310 C315 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w A 3.05 BS07 ZN A 7 C274 C277 C282 H285 C183 C186 C191 H194 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w A 3.05 BS08 CJG A 1 I109 Y111 G520 W521 Y555 Y558 C560 F562 T575 R582 F583 A584 N585 I92 Y94 G353 W354 Y388 Y391 C393 F395 T408 R415 F416 A417 N418 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKETPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w B 3.05 BS01 ZN B 1 C427 C440 C446 C450 C262 C275 C281 C285 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w B 3.05 BS02 ZN B 2 C420 C433 C440 C444 C255 C268 C275 C279 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w B 3.05 BS03 ZN B 3 C420 H422 C427 C431 C255 H257 C262 C266 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w B 3.05 BS04 ZN B 4 C457 C470 C477 C482 C292 C305 C312 C317 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w B 3.05 BS05 ZN B 5 C463 C477 C485 C498 C298 C312 C320 C333 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w B 3.05 BS06 ZN B 6 C457 C459 C463 C468 C292 C294 C298 C303 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w B 3.05 BS07 ZN B 7 C274 C277 C282 H285 C186 C189 C194 H197 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b3w B 3.05 BS08 CJG B 1 I109 Y111 G520 W521 Y555 Y558 C560 F562 R582 F583 A584 N585 I93 Y95 G355 W356 Y390 Y393 C395 F397 R417 F418 A419 N420 G1KPH4 29211475 EKGPICWRKRVKSEYMRLRQLKRFRRADEVKSMFNSNRQKIQERTEILNQEWKQRRIQPVHIMTRECSVTSDLDFPKQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDINDEIFVELVNALGQLDRRDEKPSDKIFEAISSMFPDKGTAEELKEKYKELTTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKVYNYQPCDHPRQPCDNSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADA 6b5v A 4.80 BS01 ECL A 1 F425 F456 L460 C463 I482 F377 F408 L412 C415 I434 Q9XSM3 WEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHH 6b5v B 4.80 BS01 ECL B 1 F425 F456 L460 C463 I482 F377 F408 L412 C415 I434 Q9XSM3 WEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHH 6b5v D 4.80 BS01 ECL D 1 F425 F456 L460 C463 I482 F377 F408 L412 C415 I434 Q9XSM3 WEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHH 6b5v C 4.80 BS01 ECL C 1 F425 F456 L460 C463 I482 F377 F408 L412 C415 I434 Q9XSM3 WEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHH 6b70 A 3.70 BS01 III a 1 H112 F115 S137 S138 N139 A140 F141 Y150 K192 W199 F202 G335 G339 L359 V360 G361 G362 Q363 I374 R431 Q680 M683 F820 R824 Y831 I832 H67 F70 S92 S93 N94 A95 F96 Y105 K147 W154 F157 G290 G294 L314 V315 G316 G317 Q318 I329 R386 Q635 M638 F775 R779 Y786 I787 3.4.24.56 P14735 AIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6b70 B 3.70 BS01 III c 1 H112 F115 S138 N139 A140 F141 T142 S143 Y150 E189 W199 G335 V360 G361 G362 I374 Y609 F820 R824 Y831 H67 F70 S93 N94 A95 F96 T97 S98 Y105 E144 W154 G290 V315 G316 G317 I329 Y564 F775 R779 Y786 3.4.24.56 P14735 AIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREPEVIQNMTEFKRGLPLFPLVKPH 6b7a A 1.99 BS01 CWM A 1 L73 M74 A75 N106 L72 M73 A74 N105 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7a B 1.99 BS01 CWM B 1 L73 M74 A75 M105 N106 L72 M73 A74 M104 N105 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7a B 1.99 BS02 POP B 1 T10 F11 H18 R91 S129 T9 F10 H17 R90 S128 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7b A 1.98 BS01 CWJ A 1 P8 G9 T10 A37 M74 R88 E99 L102 N106 P8 G9 T10 A37 M71 R85 E96 L99 N103 2.7.7.3 P0A6I6 29190085 MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7b B 1.98 BS01 CWJ B 1 P8 A37 M74 L102 M105 N106 P7 A36 M73 L101 M104 N105 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA 6b7b B 1.98 BS02 POP B 1 T10 F11 H18 R91 S129 T9 F10 H17 R90 S128 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA 6b7c A 1.56 BS01 CWP A 1 G9 A37 D72 L73 M74 L102 M105 N106 G8 A36 D71 L72 M73 L101 M104 N105 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7c A 1.56 BS02 POP A 1 G9 T10 F11 H18 S128 S129 G8 T9 F10 H17 S127 S128 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7c B 1.56 BS01 CWP B 1 P8 A37 S39 F70 D72 L73 M74 L102 M105 N106 P7 A36 S38 F69 D71 L72 M73 L101 M104 N105 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7c B 1.56 BS02 POP B 1 T10 F11 H18 S128 S129 T9 F10 H17 S127 S128 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7c B 1.56 BS03 DMS B 1 K42 Y98 L102 K41 Y97 L101 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7c B 1.56 BS04 DMS B 2 T26 M28 F29 D30 T25 M27 F28 D29 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7d A 1.80 BS01 CWG A 1 A37 A38 F70 S71 D72 L73 M74 L102 A37 A38 F67 S68 D69 L70 M71 L99 2.7.7.3 P0A6I6 29190085 MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7e B 2.10 BS01 CWA B 1 P8 G9 A37 F70 L73 M74 R88 Y98 L102 N106 P7 G8 A36 F69 L72 M73 R87 Y97 L101 N105 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA 6b7f A 2.56 BS01 DMS A 1 G17 H18 R91 P120 W124 G16 H17 R90 P119 W123 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7f A 2.56 BS02 POP A 1 T10 F11 H18 R91 S128 S129 T9 F10 H17 R90 S127 S128 2.7.7.3 P0A6I6 29190085 QKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLAV 6b7f B 2.56 BS01 DMS B 1 Y7 R88 G89 E99 Y5 R86 G87 E97 2.7.7.3 P0A6I6 29190085 KRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA 6b7f B 2.56 BS02 CW4 B 1 A37 F70 L73 M74 L102 N106 A35 F68 L71 M72 L100 N104 2.7.7.3 P0A6I6 29190085 KRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA 6bdz A 3.10 BS01 CA A 1 I459 C460 G461 N462 M464 E466 E469 D472 I240 C241 G242 N243 M245 E247 E250 D253 3.4.24.81 O14672 29224781 NTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRQISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRQISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPQFTDCNRHTQVCINGQCAGSICEKYGLEECTCAKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRL 6bdz A 3.10 BS02 ZN A 1 H383 H387 H393 H164 H168 H174 3.4.24.81 O14672 29224781 NTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRQISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRQISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPQFTDCNRHTQVCINGQCAGSICEKYGLEECTCAKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRL 6be6 A 2.80 BS01 ZN A 1 H383 H387 H393 H166 H170 H176 3.4.24.81 O14672 29224781 EKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRQISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRQISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPQFTDCNRHTQVCINGQCAGSICEKYGLEECTCAKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLG 6be6 A 2.80 BS02 CA A 1 I459 C460 N462 M464 E466 E469 D472 I242 C243 N245 M247 E249 E252 D255 3.4.24.81 O14672 29224781 EKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRQISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRQISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPQFTDCNRHTQVCINGQCAGSICEKYGLEECTCAKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLG 6be6 B 2.80 BS01 CA B 1 I459 C460 N462 M464 E466 E469 D472 I242 C243 N245 M247 E249 E252 D255 3.4.24.81 O14672 29224781 EKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRQISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRQISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPQFTDCNRHTQVCINGQCAGSICEKYGLEECTCAKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLG 6be6 C 2.80 BS01 ZN C 1 H383 H387 H393 H167 H171 H177 3.4.24.81 O14672 29224781 AEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRQISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRQISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPQFTDCNRHTQVCINGQCAGSICEKYGLEECTCADKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLG 6be6 C 2.80 BS02 CA C 1 I459 C460 N462 M464 E466 E469 D472 I243 C244 N246 M248 E250 E253 D256 3.4.24.81 O14672 29224781 AEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRQISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRQISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPQFTDCNRHTQVCINGQCAGSICEKYGLEECTCADKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLG 6be6 D 2.80 BS01 CA D 1 I459 C460 N462 M464 E466 E469 D472 I242 C243 N245 M247 E249 E252 D255 3.4.24.81 O14672 29224781 EKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRQISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRQISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPQFTDCNRHTQVCINGQCAGSICEKYGLEECTCASDKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLG 6bfc A 3.70 BS01 III a 1 E111 F115 S137 N139 A140 F141 T142 Y150 E189 W199 H332 G335 H336 G339 L359 V360 G361 G362 I374 R431 Y609 Q680 M683 R687 Y831 F834 E65 F69 S91 N93 A94 F95 T96 Y104 E143 W153 H286 G289 H290 G293 L313 V314 G315 G316 I328 R385 Y563 Q634 M637 R641 Y785 F788 3.4.24.56 P14735 IKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6bfc A 3.70 BS02 III a 2 A198 W199 N312 Y314 V360 N376 A152 W153 N266 Y268 V314 N330 3.4.24.56 P14735 IKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6bfc B 3.70 BS01 III b 1 H108 E111 F115 N139 A140 F141 T142 A198 W199 T220 H336 G339 L359 V360 G361 G362 Q363 K436 Y609 M683 F820 R824 Y831 I832 R847 H62 E65 F69 N93 A94 F95 T96 A152 W153 T174 H290 G293 L313 V314 G315 G316 Q317 K390 Y563 M637 F774 R778 Y785 I786 R801 3.4.24.56 P14735 IKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREEVIQNMTEFKRGLPLFPLVKPH 6bgi A 3.80 BS01 CA A 1 E650 E701 E730 D734 E310 E347 E376 D380 Q8BHY3 29236684 NVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPD 6bgi A 3.80 BS02 CA A 2 L643 N646 N647 E701 N726 E730 L303 N306 N307 E347 N372 E376 Q8BHY3 29236684 NVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPD 6bgi B 3.80 BS01 CA B 1 E650 E701 E730 D734 E310 E347 E376 D380 Q8BHY3 29236684 NVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPD 6bgi B 3.80 BS02 CA B 2 L643 N646 E701 N726 E730 L303 N306 E347 N372 E376 Q8BHY3 29236684 NVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPD 6bgj A 3.80 BS01 CA A 1 E701 E730 D734 E327 E356 D360 Q8BHY3 29236684 NVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPD 6bgj B 3.80 BS01 CA B 1 E701 E730 D734 E327 E356 D360 Q8BHY3 29236684 NVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPD 6bhu A 3.14 BS01 ATP A 1 N412 K416 W653 G681 C682 G683 K684 S685 S686 Q713 H827 E1427 N1428 S1430 G1432 Q1433 N288 K292 W525 G553 C554 G555 K556 S557 S558 Q585 H699 E1225 N1226 S1228 G1230 Q1231 Q8HXQ5 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKTNSITVKNATFTWARNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDQATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQRGLFYSMAKDSGLV 6bhu A 3.14 BS02 ATP A 2 V766 N767 S769 G770 G771 Q772 E1064 Y1301 V1308 T1328 G1329 G1331 K1332 S1333 S1334 Q1374 H1485 V638 N639 S641 G642 G643 Q644 E862 Y1099 V1106 T1126 G1127 G1129 K1130 S1131 S1132 Q1172 H1283 Q8HXQ5 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKTNSITVKNATFTWARNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDQATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQRGLFYSMAKDSGLV 6bhu A 3.14 BS03 MG A 1 S685 Q713 D792 S557 Q585 D664 Q8HXQ5 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKTNSITVKNATFTWARNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDQATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQRGLFYSMAKDSGLV 6bhu A 3.14 BS04 MG A 2 S1333 Q1374 S1131 Q1172 Q8HXQ5 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKTNSITVKNATFTWARNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDQATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQRGLFYSMAKDSGLV 6bhu A 3.14 BS05 CLR A 1 L976 I1027 T1028 G1031 M1034 I1038 L774 I825 T826 G829 M832 I836 Q8HXQ5 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKTNSITVKNATFTWARNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDQATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQRGLFYSMAKDSGLV 6bhu A 3.14 BS06 CLR A 2 M966 I969 I978 F1093 M1094 R1130 M1253 E1254 M764 I767 I776 F891 M892 R928 M1051 E1052 Q8HXQ5 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKTNSITVKNATFTWARNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDQATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQRGLFYSMAKDSGLV 6bhu A 3.14 BS07 CLR A 3 I444 V477 A481 A484 L599 I603 I606 I320 V353 A357 A360 L475 I479 I482 Q8HXQ5 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKTNSITVKNATFTWARNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDQATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQRGLFYSMAKDSGLV 6bpi A 1.64 BS01 III B 1 D299 G300 Y301 A302 C329 F332 W358 F379 D382 R384 E386 W387 I388 Y389 S392 R394 D106 G107 Y108 A109 C136 F139 W165 F186 D189 R191 E193 W194 I195 Y196 S199 R201 2.1.1.43 Q15047 ENLYFQGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMF 6bqx A 1.99 BS01 9AG A 1 H32 Q35 F36 L40 P163 H32 Q35 F36 L40 P163 P0AEG4 29237285 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6br4 A 1.99 BS01 60L A 1 H32 Q35 F36 P151 Q164 T168 M171 F174 H32 Q35 F36 P151 Q164 T168 M171 F174 P0AEG4 29237285 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6br4 B 1.99 BS01 CU B 1 H41 D44 H41 D44 P0AEG4 29237285 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6br4 B 1.99 BS02 CU B 2 Q2 E4 Q2 E4 P0AEG4 29237285 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6bvc A 1.81 BS01 COA A 1 E50 F51 A112 V113 R118 R119 Q120 G121 A123 T124 P152 A153 A155 L156 K159 E27 F28 A89 V90 R95 R96 Q97 G98 A100 T101 P129 A130 A132 L133 K136 Q53396 MGIIRTCRLGPDQVKSMRAALDLFGREFGDVATYSQHQPDSDYLGNLLRSKTFIALAAFDQEAVVGALAAYVLPKFEQPRSEIYIYDLAVSGEHRRQGIATALINLLKHEANALGAYVIYVQADYGDDPAVALYTKLGIREEVMHFDIDPSTAT 6bw3 C 2.20 BS01 III B 1 E41 W42 P43 H71 S73 D74 E126 N128 E179 Y181 D198 E231 D248 F321 N397 E32 W33 P34 H62 S64 D65 E93 N95 E146 Y148 D165 E194 D211 F284 N356 Q09028 DAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYN 6bw3 A 2.20 BS01 III D 1 E41 W42 H71 T72 S73 E126 N128 R129 E179 Y181 D198 V229 E231 D248 F321 N397 E33 W34 H63 T64 S65 E94 N96 R97 E147 Y149 D166 V197 E199 D216 F289 N361 Q09028 DDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYN 6bw4 C 2.00 BS01 III B 1 E41 W42 P43 H71 S73 E126 N128 E179 Y181 E231 D248 F321 E395 N397 E33 W34 P35 H63 S65 E94 N96 E147 Y149 E195 D212 F285 E355 N357 Q09028 DDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYN 6bw4 A 2.00 BS01 III D 1 E41 W42 P43 H71 S73 E126 N128 R129 E179 Y181 V229 E231 D248 F321 E395 N397 E37 W38 P39 H67 S69 E97 N99 R100 E150 Y152 V200 E202 D219 F292 E362 N364 Q09028 EAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYN 6em3 v 3.20 BS01 NUC 2 1 S12 S13 S10 S11 P40007 29245012 SVRKRKMNRSSVGKATRRNKDKQRKINIQSNPIIAANWDYSLTMAQNYKKLGLRAKLQTPAGGKETEVVKKLEELASRSQSEREEEWLEKLYKKHGDDYKKMFFDKKLNIYQQSEGDLKRRLLRWKKRNG 6em3 h 3.20 BS01 NUC 2 1 A2 A52 C53 T85 R86 A1 A51 C52 T84 R85 P0CX84 29245012 AGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA 6em3 j 3.20 BS01 NUC 2 1 R21 C22 G23 T59 G60 G62 M64 R65 Y66 L67 R73 Q79 G81 S82 K85 R7 C8 G9 T45 G46 G48 M50 R51 Y52 L53 R59 Q65 G67 S68 K71 P49166 29245012 SHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASK 6em3 P 3.20 BS01 NUC 2 1 Q121 P123 Q92 P94 P05740 29245012 NPAKSASARGSYLRVSFKNTRETAQAINGWELTKAQKYLEQVLDHQRAIPKARWPAKSVKFVQGLLQNAAANAEAKGLDATKLYVSHIQVNQAPKESSPSHIELVVTEKEEAVAKAA 6em3 Y 3.20 BS01 NUC 2 1 S24 S25 R51 R52 V73 R75 S23 S24 R50 R51 V72 R74 P05743 29245012 AKQSLDVSSDRRKARKAYFTAPSSQRRVLLSAPLSKELRAQYGIKALPIRRDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPSKLVITKLHLDKDRKALIQRKGGKL 6em3 K 3.20 BS01 NUC 6 1 S185 T188 P191 G195 G196 T221 G241 T243 S286 P287 S136 T139 P142 G146 G147 T172 G192 T194 S237 P238 P38779 29245012 AIPRERVIKAVNELIKFTSKPEEELKKDLQLIVVNNKSFTGTSKSFKLKLLNVKHSFYKPWKEASATAVKDFKVLLILKDSDIKKVSEDDLFDQLDSEGIKVDEIICGKDLKTVYKAYEARNAFISQFSLILADDSIVTSLPKLMGGKAYNKVETTPISIRTHANKEFSLTTLTNNIKKVYMNQLPVKLPRGTTLNVHLGNLEWLRPEEFVDNVELISEQLIKAYQIRSIFIKTNRSPVLPLYYNQ 6em3 o 3.20 BS01 NUC 6 1 R132 E174 K175 R45 E87 K88 P53927 29245012 EYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQESMNNYLLMGHLLQVRVLPKGAKIEKLYKYKKRKQLKDNMKQKHEERIKKLAKS 6em3 t 3.20 BS01 NUC 6 1 Q91 H92 I93 A94 S95 E170 T171 S302 N303 Q38 H39 I40 A41 S42 E96 T97 S228 N229 P40693 29245012 KFVRAESIVAKTLATSREKERIKRVSILEDKKAKNETQHIASGKDFILKITEGLIREKTTYDGKPALLFIVRVRGPLAVNIPNKAFKILSLLRLVETNTGVFVKLTKNVYPLLKVIAPYVVIGKPSLSSIRSLIQKRGRIIYKGENEAEPHEIVLNDNNIVEEQLGDHGIICVEDIIHEIATMGESFSVCNFFLQPFKLNREVSGFGSLNRLRKIKQREAESRTRQFSNAATAPVIEVDIDSLLAKLN 6emf B 2.65 BS01 PRO B 1 Q68 N72 R118 Q63 N67 R113 G0S4M2 29245012 KSMPFIKHLASSDRKVRTAALNSLHAFLSARQVASALTTLDVLKLWKGLFYALWMCDRAIPQQNLCNELADLIWQLPRESVATWLRGFWATMAREWTGIDVLRMEKFLLLVRRVLGASFKWMKKDGSTGAWDQSKVDEVLGLLAEWPFSLAEEVRITGEIVQKIPVGMRLHVLDIWVDEVERVGLLNEDEEEARMIVQRISDMVDALEQTTKSPAVRTRSKDSLGDDRLPANR 6emf B 2.65 BS02 PRO B 2 L48 K49 R99 L43 K44 R94 G0S4M2 29245012 KSMPFIKHLASSDRKVRTAALNSLHAFLSARQVASALTTLDVLKLWKGLFYALWMCDRAIPQQNLCNELADLIWQLPRESVATWLRGFWATMAREWTGIDVLRMEKFLLLVRRVLGASFKWMKKDGSTGAWDQSKVDEVLGLLAEWPFSLAEEVRITGEIVQKIPVGMRLHVLDIWVDEVERVGLLNEDEEEARMIVQRISDMVDALEQTTKSPAVRTRSKDSLGDDRLPANR 6erc A 2.50 BS01 HEM A 1 N93 G96 Q97 I100 A104 L105 S106 R233 E236 Y290 T317 F321 R322 F323 G324 H325 E327 V328 I347 Y351 L384 L399 R402 N403 R406 N73 G76 Q77 I80 A84 L85 S86 R213 E216 Y270 T297 F301 R302 F303 G304 H305 E307 V308 I327 Y331 L364 L379 R382 N383 R386 1.11.1.7 Q6TMK4 29242189 SQEFRSYTGEGNNKQNPKQGSIFTPFIRLANPIKFNKNGFPNITNQPSRAISNIIFDQQTHIGSKEHLTDMFNMWGQFLIHNMALSKPEPNSWPIKVPKCDQYFDPACIGNKTMNYFRTRATEVPCDVGKTVVDEDGKCYEQINSLGSYIDGNVLYGNSEEICKNLRSLSGGEMKMTVTDVGDLPPKNVPGVPMDNDANLFPIDQLYSVGERRGNENPGLLSIHTLLLRDHNRLARKFARLHPEWDDERVFQQSRSCIIEQIQKITYDEYLPTTLGSFPSYTGYDANVNAQVSNEFTTTAFRFGHSEVGPFMEYYSENGTRLQPLPIKFSYFNPHALNRGVEPLIRGLIINEEENIDIYMISDLRNFLFGKPGQGGLDLASRNLQRNRDHGIPPYNSLRRQLGLRPVQTWSDITSDPQIQNRLKNAYKSVDDIDSYVGGLAEDHMEGSCVGQTFYLIIYEQFFRTRAGDRFWYETPEMRMVNRECETTTFAEVIKRTTSNIGYVQPNVFRK 6erc A 2.50 BS02 CA A 1 S326 E374 N375 D377 Y379 S306 E354 N355 D357 Y359 1.11.1.7 Q6TMK4 29242189 SQEFRSYTGEGNNKQNPKQGSIFTPFIRLANPIKFNKNGFPNITNQPSRAISNIIFDQQTHIGSKEHLTDMFNMWGQFLIHNMALSKPEPNSWPIKVPKCDQYFDPACIGNKTMNYFRTRATEVPCDVGKTVVDEDGKCYEQINSLGSYIDGNVLYGNSEEICKNLRSLSGGEMKMTVTDVGDLPPKNVPGVPMDNDANLFPIDQLYSVGERRGNENPGLLSIHTLLLRDHNRLARKFARLHPEWDDERVFQQSRSCIIEQIQKITYDEYLPTTLGSFPSYTGYDANVNAQVSNEFTTTAFRFGHSEVGPFMEYYSENGTRLQPLPIKFSYFNPHALNRGVEPLIRGLIINEEENIDIYMISDLRNFLFGKPGQGGLDLASRNLQRNRDHGIPPYNSLRRQLGLRPVQTWSDITSDPQIQNRLKNAYKSVDDIDSYVGGLAEDHMEGSCVGQTFYLIIYEQFFRTRAGDRFWYETPEMRMVNRECETTTFAEVIKRTTSNIGYVQPNVFRK 6erc A 2.50 BS03 MPD A 1 D77 Q78 Q79 T80 I82 Y379 Q438 R442 D57 Q58 Q59 T60 I62 Y359 Q418 R422 1.11.1.7 Q6TMK4 29242189 SQEFRSYTGEGNNKQNPKQGSIFTPFIRLANPIKFNKNGFPNITNQPSRAISNIIFDQQTHIGSKEHLTDMFNMWGQFLIHNMALSKPEPNSWPIKVPKCDQYFDPACIGNKTMNYFRTRATEVPCDVGKTVVDEDGKCYEQINSLGSYIDGNVLYGNSEEICKNLRSLSGGEMKMTVTDVGDLPPKNVPGVPMDNDANLFPIDQLYSVGERRGNENPGLLSIHTLLLRDHNRLARKFARLHPEWDDERVFQQSRSCIIEQIQKITYDEYLPTTLGSFPSYTGYDANVNAQVSNEFTTTAFRFGHSEVGPFMEYYSENGTRLQPLPIKFSYFNPHALNRGVEPLIRGLIINEEENIDIYMISDLRNFLFGKPGQGGLDLASRNLQRNRDHGIPPYNSLRRQLGLRPVQTWSDITSDPQIQNRLKNAYKSVDDIDSYVGGLAEDHMEGSCVGQTFYLIIYEQFFRTRAGDRFWYETPEMRMVNRECETTTFAEVIKRTTSNIGYVQPNVFRK 6erc B 2.50 BS01 CA B 1 S326 N375 D377 Y379 S306 N355 D357 Y359 1.11.1.7 Q6TMK4 29242189 SQEFRSYTGEGNNKQNPKQGSIFTPFIRLANPIKFNKNGFPNITNQPSRAISNIIFDQQTHIGSKEHLTDMFNMWGQFLIHNMALSKPEPNSWPIKVPKCDQYFDPACIGNKTMNYFRTRATEVPCDVGKTVVDEDGKCYEQINSLGSYIDGNVLYGNSEEICKNLRSLSGGEMKMTVTDVGDLPPKNVPGVPMDNDANLFPIDQLYSVGERRGNENPGLLSIHTLLLRDHNRLARKFARLHPEWDDERVFQQSRSCIIEQIQKITYDEYLPTTLGSFPSYTGYDANVNAQVSNEFTTTAFRFGHSEVGPFMEYYSENGTRLQPLPIKFSYFNPHALNRGVEPLIRGLIINEEENIDIYMISDLRNFLFGKPGQGGLDLASRNLQRNRDHGIPPYNSLRRQLGLRPVQTWSDITSDPQIQNRLKNAYKSVDDIDSYVGGLAEDHMEGSCVGQTFYLIIYEQFFRTRAGDRFWYETPEMRMVNRECETTTFAEVIKRTTSNIGYVQPNVFRK 6erc B 2.50 BS02 HEM B 1 N93 G96 Q97 I100 A104 L105 S106 R233 E236 Y290 T317 F321 R322 G324 H325 E327 V328 I347 Y351 L384 L388 F389 L399 R402 N403 R406 N73 G76 Q77 I80 A84 L85 S86 R213 E216 Y270 T297 F301 R302 G304 H305 E307 V308 I327 Y331 L364 L368 F369 L379 R382 N383 R386 1.11.1.7 Q6TMK4 29242189 SQEFRSYTGEGNNKQNPKQGSIFTPFIRLANPIKFNKNGFPNITNQPSRAISNIIFDQQTHIGSKEHLTDMFNMWGQFLIHNMALSKPEPNSWPIKVPKCDQYFDPACIGNKTMNYFRTRATEVPCDVGKTVVDEDGKCYEQINSLGSYIDGNVLYGNSEEICKNLRSLSGGEMKMTVTDVGDLPPKNVPGVPMDNDANLFPIDQLYSVGERRGNENPGLLSIHTLLLRDHNRLARKFARLHPEWDDERVFQQSRSCIIEQIQKITYDEYLPTTLGSFPSYTGYDANVNAQVSNEFTTTAFRFGHSEVGPFMEYYSENGTRLQPLPIKFSYFNPHALNRGVEPLIRGLIINEEENIDIYMISDLRNFLFGKPGQGGLDLASRNLQRNRDHGIPPYNSLRRQLGLRPVQTWSDITSDPQIQNRLKNAYKSVDDIDSYVGGLAEDHMEGSCVGQTFYLIIYEQFFRTRAGDRFWYETPEMRMVNRECETTTFAEVIKRTTSNIGYVQPNVFRK 6erc B 2.50 BS03 MPD B 1 D77 Q78 Q79 T80 I82 Y379 Q438 R442 D57 Q58 Q59 T60 I62 Y359 Q418 R422 1.11.1.7 Q6TMK4 29242189 SQEFRSYTGEGNNKQNPKQGSIFTPFIRLANPIKFNKNGFPNITNQPSRAISNIIFDQQTHIGSKEHLTDMFNMWGQFLIHNMALSKPEPNSWPIKVPKCDQYFDPACIGNKTMNYFRTRATEVPCDVGKTVVDEDGKCYEQINSLGSYIDGNVLYGNSEEICKNLRSLSGGEMKMTVTDVGDLPPKNVPGVPMDNDANLFPIDQLYSVGERRGNENPGLLSIHTLLLRDHNRLARKFARLHPEWDDERVFQQSRSCIIEQIQKITYDEYLPTTLGSFPSYTGYDANVNAQVSNEFTTTAFRFGHSEVGPFMEYYSENGTRLQPLPIKFSYFNPHALNRGVEPLIRGLIINEEENIDIYMISDLRNFLFGKPGQGGLDLASRNLQRNRDHGIPPYNSLRRQLGLRPVQTWSDITSDPQIQNRLKNAYKSVDDIDSYVGGLAEDHMEGSCVGQTFYLIIYEQFFRTRAGDRFWYETPEMRMVNRECETTTFAEVIKRTTSNIGYVQPNVFRK 6ev4 A 1.14 BS01 4LU A 1 T153 N168 S170 I171 A172 R173 Q190 H191 S223 S224 M225 P226 E233 C316 T323 I327 K391 T150 N165 S167 I168 A169 R170 Q187 H188 S220 S221 M222 P223 E230 C313 T320 I324 K388 4.1.1.102 A2QHE5 QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGRLARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPDGTWTNWSIARAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGSSLELVKCDTNDLYVPATSEIVLEGTLSISETGPEGPFGEMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDETHTMIGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVGDDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPEDLKQKVLDNWTKMGFSHHHH 6ev4 A 1.14 BS02 MN A 1 N168 H191 E233 N165 H188 E230 4.1.1.102 A2QHE5 QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGRLARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPDGTWTNWSIARAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGSSLELVKCDTNDLYVPATSEIVLEGTLSISETGPEGPFGEMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDETHTMIGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVGDDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPEDLKQKVLDNWTKMGFSHHHH 6ez6 A 2.04 BS01 C5Z A 1 T750 S754 W760 I777 K779 L784 D787 I825 E826 V827 V828 D832 T833 M900 I910 D911 T589 S593 W599 I616 K618 L623 D626 I664 E665 V666 V667 D671 T672 M739 I749 D750 2.7.1.153 O35904 29232121 DRVKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPASLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVDCPIAWANLMLFDYKDQLKTGERCLYMWPSVLLNPAGTVRGNPNTESAAALVIYLPEVAPHPVYFPALEKILELGRHGERGRITEEEQLQLREILERGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVN 6f0a A 2.26 BS01 C82 A 1 L124 V125 Y126 C129 V130 F163 F164 S167 L234 G262 S263 A264 L114 V115 Y116 C119 V120 F153 F154 S157 L224 G252 S253 A254 1.13.11.52 P14902 29240291 ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG 6f0a A 2.26 BS02 ALA A 1 F163 F226 R231 I354 G378 T379 F153 F216 R221 I344 G358 T359 1.13.11.52 P14902 29240291 ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG 6f0a A 2.26 BS03 HEM A 1 F163 S167 V170 F214 F226 S263 A264 G265 F270 R343 H346 I349 V350 Y353 I354 G378 T379 G380 G381 T382 L384 F387 L388 V391 F153 S157 V160 F204 F216 S253 A254 G255 F260 R333 H336 I339 V340 Y343 I344 G358 T359 G360 G361 T362 L364 F367 L368 V371 1.13.11.52 P14902 29240291 ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG 6f0a C 2.26 BS01 C82 C 1 L124 V125 Y126 C129 V130 F163 F164 S167 L234 G262 S263 A264 L114 V115 Y116 C119 V120 F153 F154 S157 L224 G252 S253 A254 1.13.11.52 P14902 29240291 ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPLEAKGTGGTDLMNFLKTVRSTTEKSLLKE 6f0a C 2.26 BS02 ALA C 1 F163 F226 R231 I354 G378 T379 F153 F216 R221 I344 G357 T358 1.13.11.52 P14902 29240291 ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPLEAKGTGGTDLMNFLKTVRSTTEKSLLKE 6f0a C 2.26 BS03 HEM C 1 Y126 F163 S167 V170 F214 I217 F226 S263 A264 G265 F270 R343 H346 I349 V350 Y353 I354 G378 T379 G380 T382 L384 F387 L388 V391 Y116 F153 S157 V160 F204 I207 F216 S253 A254 G255 F260 R333 H336 I339 V340 Y343 I344 G357 T358 G359 T361 L363 F366 L367 V370 1.13.11.52 P14902 29240291 ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPLEAKGTGGTDLMNFLKTVRSTTEKSLLKE 6f0y A BS01 III B 1 E39 D58 S59 I60 L61 V62 G63 P64 V65 P66 V69 N70 K71 F72 E42 D61 S62 I63 L64 V65 G66 P67 V68 P69 V72 N73 K74 F75 P32447 GAMGSIVSLLGIKVLNNPAKFTDPYEFEITFECLESLKHDLEWKLTYVGSSRSLDHDQELDSILVGPVPVGVNKFVFSADPPSAELIPASELVSVTVILLSCSYDGREFVRVGYYVNNEYDEEELRENPPAKVQVDHIVRNILAEKPRVTRFNIVWDNENEGDLYPPEQPGV 6f3f A 2.42 BS01 ADP A 1 L273 G274 G276 V281 A293 K295 V323 T338 E339 Y340 M341 G344 S345 D348 R388 A390 N391 L393 D404 L193 G194 G196 V201 A213 K215 V243 T258 E259 Y260 M261 G264 S265 D268 R308 A310 N311 L313 D324 2.7.10.2 Q3UKD6 29234112 RMVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 6f3f A 2.42 BS02 MG A 1 K295 N391 D404 K215 N311 D324 2.7.10.2 Q3UKD6 29234112 RMVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP