5h60 A 3.64 BS01 UDP A 1 Q50 W51 F52 Y74 Y221 D223 A224 D225 S324 S329 S330 W331 Q21 W22 F23 Y45 Y192 D194 A195 D196 S295 S300 S301 W302 SFNGKDYPLCFLDEKTPLLFQWFERNPARFGKNDIPIINTEKNPYLNNIIKAATIEKERLIGIFVDGDFFPGQKDAFSKLEYDYENIKVIYRNDIDFSMYDKKLSEIYMENISKQESMPEEKRDCHLLQLLKKELSDIQEGNDSLIKSYLLDKGHGWFDFYRNMAMLKAGQLFLEADKVGCYDLSTNSGCIYLDADMIITEKLGGIYIPDGIAVHVERIDGRASMENGIIAVDRNNHPALLAGLEIMHTKFDADPYSDGVCNGIRKHFNYSLNEDYNSFCDFIEFKHDNIIMNTSQFTQSSWAR 5h60 A 3.64 BS02 MN A 1 D225 N322 S324 D196 N293 S295 SFNGKDYPLCFLDEKTPLLFQWFERNPARFGKNDIPIINTEKNPYLNNIIKAATIEKERLIGIFVDGDFFPGQKDAFSKLEYDYENIKVIYRNDIDFSMYDKKLSEIYMENISKQESMPEEKRDCHLLQLLKKELSDIQEGNDSLIKSYLLDKGHGWFDFYRNMAMLKAGQLFLEADKVGCYDLSTNSGCIYLDADMIITEKLGGIYIPDGIAVHVERIDGRASMENGIIAVDRNNHPALLAGLEIMHTKFDADPYSDGVCNGIRKHFNYSLNEDYNSFCDFIEFKHDNIIMNTSQFTQSSWAR 5h63 A 1.92 BS01 UD1 A 1 Q64 W65 F66 Y88 H200 F203 D204 R207 Y237 D239 A240 D241 H260 N272 G273 N338 S340 S345 S346 W347 R348 Q25 W26 F27 Y49 H161 F164 D165 R168 Y198 D200 A201 D202 H221 N233 G234 N299 S301 S306 S307 W308 R309 SGHVSFAGIDYPLLPLNHQTPLVFQWFERNPDRFGQNEIPIINTQKNPYLNNIINAAIIEKERIIGIFVDGDFSKGQRKALGKLEQNYRNIKVIYNSDLNYSMYDKKLTTIYLENITKLEAQSASERDEVLLNGVKKSLEDVLKNNPEETLISSHNKDKGHLWFDFYRNLFLLKGSDAFLEAGKPGCHHLQPGGGCIYLDADMLLTDKLGTLYLPDGIAIHVSRKDNHVSLENGIIAVNRSEHPALIKGLEIMHSKPYGDPYNDWLSKGLRHYFDGSHIQDYDAFCDFIEFKHENIIMNTSSLTASSWR 5h63 A 1.92 BS02 MN A 1 D241 N338 S340 D202 N299 S301 SGHVSFAGIDYPLLPLNHQTPLVFQWFERNPDRFGQNEIPIINTQKNPYLNNIINAAIIEKERIIGIFVDGDFSKGQRKALGKLEQNYRNIKVIYNSDLNYSMYDKKLTTIYLENITKLEAQSASERDEVLLNGVKKSLEDVLKNNPEETLISSHNKDKGHLWFDFYRNLFLLKGSDAFLEAGKPGCHHLQPGGGCIYLDADMLLTDKLGTLYLPDGIAIHVSRKDNHVSLENGIIAVNRSEHPALIKGLEIMHSKPYGDPYNDWLSKGLRHYFDGSHIQDYDAFCDFIEFKHENIIMNTSSLTASSWR 5h63 A 1.92 BS03 MN A 2 D322 D326 D283 D287 SGHVSFAGIDYPLLPLNHQTPLVFQWFERNPDRFGQNEIPIINTQKNPYLNNIINAAIIEKERIIGIFVDGDFSKGQRKALGKLEQNYRNIKVIYNSDLNYSMYDKKLTTIYLENITKLEAQSASERDEVLLNGVKKSLEDVLKNNPEETLISSHNKDKGHLWFDFYRNLFLLKGSDAFLEAGKPGCHHLQPGGGCIYLDADMLLTDKLGTLYLPDGIAIHVSRKDNHVSLENGIIAVNRSEHPALIKGLEIMHSKPYGDPYNDWLSKGLRHYFDGSHIQDYDAFCDFIEFKHENIIMNTSSLTASSWR 5h63 C 1.92 BS01 MN B 3 D299 N302 D259 N262 GHVSFAGIDYPLLPLNHQTPLVFQWFERNPDRFGQNEIPIINTQKNPYLNNIINAAIIEKERIIGIFVDGDFSKGQRKALGKLEQNYRNIKVIYNSDLNYSMYDKKLTTIYLENITKLEAQSASERDEVLLNGVKKSLEDVLKNNPEETLISSHNKDKGHLWFDFYRNLFLLKGSDAFLEAGKPGCHHLQPGGGCIYLDADMLLTDKLGTLYLPDGIAIHVSRKDNHVSLENGIIAVNRSEHPALIKGLEIMHSKPYGDPYNDWLSKGLRHYFDGSHIQDYDAFCDFIEFKHENIIMNTSSL 5h63 C 1.92 BS02 UD1 C 1 Q64 W65 F66 Y88 H200 F203 D204 R207 Y237 D239 A240 D241 E271 N272 G273 N338 S340 Q24 W25 F26 Y48 H160 F163 D164 R167 Y197 D199 A200 D201 E231 N232 G233 N298 S300 GHVSFAGIDYPLLPLNHQTPLVFQWFERNPDRFGQNEIPIINTQKNPYLNNIINAAIIEKERIIGIFVDGDFSKGQRKALGKLEQNYRNIKVIYNSDLNYSMYDKKLTTIYLENITKLEAQSASERDEVLLNGVKKSLEDVLKNNPEETLISSHNKDKGHLWFDFYRNLFLLKGSDAFLEAGKPGCHHLQPGGGCIYLDADMLLTDKLGTLYLPDGIAIHVSRKDNHVSLENGIIAVNRSEHPALIKGLEIMHSKPYGDPYNDWLSKGLRHYFDGSHIQDYDAFCDFIEFKHENIIMNTSSL 5lme A BS01 ZN A 1 C8 C11 C31 H34 C8 C11 C31 H34 Q27026 VMKKRTYCTYCPSKIRRKANASCKKCKKVICREHNIDMCQSCF 5lme A BS02 ZN A 2 C23 C26 C39 C42 C23 C26 C39 C42 Q27026 VMKKRTYCTYCPSKIRRKANASCKKCKKVICREHNIDMCQSCF 5m00 A 1.95 BS01 III P 1 Y7 E9 Y59 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 L95 Q97 S99 F116 Y123 T143 K146 W147 S150 A152 H155 Y156 Y159 W167 Y171 Y7 E9 Y59 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 L95 Q97 S99 F116 Y123 T143 K146 W147 S150 A152 H155 Y156 Y159 W167 Y171 P01899 GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWEP 5m1r A 1.64 BS01 ADP A 1 G213 A214 K219 G237 G238 L256 G312 L313 N336 G337 G340 V341 E343 D374 T375 G213 A214 K219 G237 G238 L256 G312 L313 N336 G337 G340 V341 E343 D374 T375 2.7.2.3 P00558 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFDTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 5m1r A 1.64 BS02 MG A 1 N336 G372 D374 T375 N336 G372 D374 T375 2.7.2.3 P00558 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFDTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 5m1r A 1.64 BS03 MG A 2 R150 A151 N179 R150 A151 N179 2.7.2.3 P00558 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFDTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 5m3c A 2.80 BS01 CA A 1 E1015 N1074 E1106 D1136 E201 N260 E292 D322 A0A140SCF9 HHDPLTGLPNRLLFESRLNHALDEAREESRPGAVLFIDLDRFKHINDSLGHPIGDLLLKAIAERLRDQLRDVDTVARLGGDEFIILLPGLHQESDAEHVARKLLNAFTAPFFFVSASVGIALFPKDGDDAPTLVKNADAAMYRAKSRGRSRIEYYTRELTYLATERMALETELRRALERDELQLYYQPKLSLESGLLVGAEALVRWYHPLFGEISPERFIPLAEDCGLILPLGDWVLEHACQQMGEWQKLHAPFGPLSVNLAGAQLGQPQLIERLEQLLEQSGLEPSRLQLEITESFIMNQTEEALAVLHGLKRLGVQLAIDDFGTGYSSLSYLKRLPLDILKIDKSFIRGLPDDPHDAAITRAIIALGRSMQLTVIAEGVETEGQQSFLTHEGCEQIQGFVLSPPLPAELFASKFLKPR 5m3c A 2.80 BS02 CA A 2 D846 L847 D889 D38 L39 D81 A0A140SCF9 HHDPLTGLPNRLLFESRLNHALDEAREESRPGAVLFIDLDRFKHINDSLGHPIGDLLLKAIAERLRDQLRDVDTVARLGGDEFIILLPGLHQESDAEHVARKLLNAFTAPFFFVSASVGIALFPKDGDDAPTLVKNADAAMYRAKSRGRSRIEYYTRELTYLATERMALETELRRALERDELQLYYQPKLSLESGLLVGAEALVRWYHPLFGEISPERFIPLAEDCGLILPLGDWVLEHACQQMGEWQKLHAPFGPLSVNLAGAQLGQPQLIERLEQLLEQSGLEPSRLQLEITESFIMNQTEEALAVLHGLKRLGVQLAIDDFGTGYSSLSYLKRLPLDILKIDKSFIRGLPDDPHDAAITRAIIALGRSMQLTVIAEGVETEGQQSFLTHEGCEQIQGFVLSPPLPAELFASKFLKPR 5m3c A 2.80 BS03 CA A 3 D846 D889 E890 D38 D81 E82 A0A140SCF9 HHDPLTGLPNRLLFESRLNHALDEAREESRPGAVLFIDLDRFKHINDSLGHPIGDLLLKAIAERLRDQLRDVDTVARLGGDEFIILLPGLHQESDAEHVARKLLNAFTAPFFFVSASVGIALFPKDGDDAPTLVKNADAAMYRAKSRGRSRIEYYTRELTYLATERMALETELRRALERDELQLYYQPKLSLESGLLVGAEALVRWYHPLFGEISPERFIPLAEDCGLILPLGDWVLEHACQQMGEWQKLHAPFGPLSVNLAGAQLGQPQLIERLEQLLEQSGLEPSRLQLEITESFIMNQTEEALAVLHGLKRLGVQLAIDDFGTGYSSLSYLKRLPLDILKIDKSFIRGLPDDPHDAAITRAIIALGRSMQLTVIAEGVETEGQQSFLTHEGCEQIQGFVLSPPLPAELFASKFLKPR 5m3c A 2.80 BS04 GTP A 1 D846 L847 R849 F850 K851 N854 H859 G862 D863 L866 R885 G888 D889 K959 R963 D38 L39 R41 F42 K43 N46 H51 G54 D55 L58 R77 G80 D81 K145 R149 A0A140SCF9 HHDPLTGLPNRLLFESRLNHALDEAREESRPGAVLFIDLDRFKHINDSLGHPIGDLLLKAIAERLRDQLRDVDTVARLGGDEFIILLPGLHQESDAEHVARKLLNAFTAPFFFVSASVGIALFPKDGDDAPTLVKNADAAMYRAKSRGRSRIEYYTRELTYLATERMALETELRRALERDELQLYYQPKLSLESGLLVGAEALVRWYHPLFGEISPERFIPLAEDCGLILPLGDWVLEHACQQMGEWQKLHAPFGPLSVNLAGAQLGQPQLIERLEQLLEQSGLEPSRLQLEITESFIMNQTEEALAVLHGLKRLGVQLAIDDFGTGYSSLSYLKRLPLDILKIDKSFIRGLPDDPHDAAITRAIIALGRSMQLTVIAEGVETEGQQSFLTHEGCEQIQGFVLSPPLPAELFASKFLKPR 5m3c B 2.80 BS01 CA B 1 D846 L847 D889 K959 D38 L39 D81 K151 A0A140SCF9 HHDPLTGLPNRLLFESRLNHALDEAREESRPGAVLFIDLDRFKHINDSLGHPIGDLLLKAIAERLRDQLRDVDTVARLGGDEFIILLPGLHQESDAEHVARKLLNAFTAPFQADGHEFFVSASVGIALFPKDGDDAPTLVKNADAAMYRAKSRGRSRIEYYTRELTYLATERMALETELRRALERDELQLYYQPKLSLESGLLVGAEALVRWYHPLFGEISPERFIPLAEDCGLILPLGDWVLEHACQQMGEWQKLHAPFGPLSVNLAGAQLGQPQLIERLEQLLEQSGLEPSRLQLEITESFIMNQTEEALAVLHGLKRLGVQLAIDDFGTGYSSLSYLKRLPLDILKIDKSFIRGLPDDPHDAAITRAIIALGRSMQLTVIAEGVETEGQQSFLTHEGCEQIQGFVLSPPLPAELFASKFLKPR 5m3c B 2.80 BS03 GTP B 1 L847 D848 R849 F850 K851 N854 H859 G862 D863 L866 R885 G888 D889 K959 R963 L39 D40 R41 F42 K43 N46 H51 G54 D55 L58 R77 G80 D81 K151 R155 A0A140SCF9 HHDPLTGLPNRLLFESRLNHALDEAREESRPGAVLFIDLDRFKHINDSLGHPIGDLLLKAIAERLRDQLRDVDTVARLGGDEFIILLPGLHQESDAEHVARKLLNAFTAPFQADGHEFFVSASVGIALFPKDGDDAPTLVKNADAAMYRAKSRGRSRIEYYTRELTYLATERMALETELRRALERDELQLYYQPKLSLESGLLVGAEALVRWYHPLFGEISPERFIPLAEDCGLILPLGDWVLEHACQQMGEWQKLHAPFGPLSVNLAGAQLGQPQLIERLEQLLEQSGLEPSRLQLEITESFIMNQTEEALAVLHGLKRLGVQLAIDDFGTGYSSLSYLKRLPLDILKIDKSFIRGLPDDPHDAAITRAIIALGRSMQLTVIAEGVETEGQQSFLTHEGCEQIQGFVLSPPLPAELFASKFLKPR 5m3k B 2.83 BS01 ZN B 1 C34 C37 C48 C51 C32 C35 C46 C49 Q4K419 MYPEQIHRMTTASMLREWREHGGKYRLEGSQCEECNEIFFPRRTVCGACNSLSVKPYRCARSGKIEVMAPAENPILAAMGYGETVPRIMAMVRLDDGLVIASEIVDVCDQQQLKVGAPVRMVIRKHVRESNLAWQYAYKFVLDI 5m3u A 1.81 BS01 ADP A 1 G213 A214 K219 G237 G238 L256 G312 L313 N336 P338 G340 V341 E343 G372 G373 D374 T375 G213 A214 K219 G237 G238 L256 G312 L313 N336 P338 G340 V341 E343 G372 G373 D374 T375 2.7.2.3 P00558 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKFADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 5m3u A 1.81 BS02 3PG A 1 D23 N25 R38 H62 R65 R122 R170 D23 N25 R38 H62 R65 R122 R170 2.7.2.3 P00558 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKFADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 5m3u A 1.81 BS03 MG A 1 K5 D411 L413 N415 K5 D411 L413 N415 2.7.2.3 P00558 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKFADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 5m4z A 1.18 BS01 7K8 A 1 Y129 C189 H190 Q208 R209 S210 A211 D212 N220 H250 Y252 Y109 C169 H170 Q188 R189 S190 A191 D192 N200 H230 Y232 2.1.1.45 Q9NDD3 YVNQEELNYLNQLKDIIDHGVRKNGIGTLSTFGTQSRYCLRDDIFPLLTTKRVFWRGVVEELLWFISGSTNAKQLSEKNVNIWDGNSSREFLDSRGLYNYEEGDLGPVYGFQWRHFGCPYSSMTADYKGKGYDQLQQCIKMIREEPESRRIIMTAWNPCDLEKVALPPCHCFVQFYVADGELSCQMYQRSADMGLGVPFNIASYSLLTRMIAHITSLKPGFFIHTIGDAHVYLTHVDALKVQMERKPRPFPKLKILRNVENIDDFRAEDFELINYKPYPKISMPMAV 5m4z B 1.18 BS02 7K8 B 1 R43 W103 Y129 L186 C189 H190 Q208 R209 S210 A211 D212 N220 H250 Y252 R26 W86 Y112 L169 C172 H173 Q191 R192 S193 A194 D195 N203 H233 Y235 2.1.1.45 Q9NDD3 YVNQEELNYLNQLKDIIDHGVRKNDRTGIGTLSTFGTQSRYCLRDDIFPLLTTKRVFWRGVVEELLWFISGSTNAKQLSEKNVNIWDGNSSREFLDSRGLYNYEEGDLGPVYGFQWRHFGCPYSSMTADYKGKGYDQLQQCIKMIREEPESRRIIMTAWNPCDLEKVALPPCHCFVQFYVADGELSCQMYQRSADMGLGVPFNIASYSLLTRMIAHITSLKPGFFIHTIGDAHVYLTHVDALKVQMERKPRPFPKLKILRNVENIDDFRAEDFELINYKPYPKISM 5m6j A 1.70 BS01 HEM A 1 V27 Y30 F41 F43 L58 H60 F69 F88 Y107 I121 I123 L135 V26 Y29 F40 F42 L57 H59 F68 F87 Y106 I120 I122 L134 1.7.6.1 Q6PQK2 PGECSVNVIPKKNLDKAKFFSGTWYVTHYLDMDPQATEKFCFSFAPRESGGTVKEALYHFNVDSKVSFYNTGTGPLESNGAKYTAKFNTVDKKGKEIKPADEKYSYTVTVIEAAKQSALIHICLQEDGKDIGDLYSVLNRNKNALPNKKIKKALNKVSLVLTKFVVTKDLDCKYDDKFLSSWQK 5m6k A 1.60 BS01 HEM A 1 V27 Y30 F41 F43 E56 L58 H60 F69 N71 F88 Y107 V109 I121 I123 L135 S137 V26 Y29 F40 F42 E55 L57 H59 F68 N70 F87 Y106 V108 I120 I122 L134 S136 1.7.6.1 Q6PQK2 PGECSVNVIPKKNLDKAKFFSGTWYVTHYLDMDPQATEKFCFSFAPRESGGTVKEALYHFNVDSKVSFYNTGTGPLESNGAKYTAKFNTVDKKGKEIKPADEKYSYTVTVIEAAKQSALIHICLQEDGKDIGDLYSVLNRNKNALPNKKIKKALNKVSLVLTKFVVTKDLDCKYDDKFLSSWQK 5m7h A 3.15 BS01 PO4 A 1 N13 G15 K16 S17 N11 G13 K14 S15 P50743 KPVVAIVGRPNVGKSTIFNRIAGERISEDTPDRIYSSAEWLNYDFNLIDTGGIGDEPFLAQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHFKNIPETKYNEEVIQFCLIGRPNVGKSSLVNAMLGEERVIVSNTTRDAVDTSFTYNQQEFVIVDTAGMRKKGKVYETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVDKDESTMKEFEENIRDHFQFLDYAPILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVSVKPPSFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIFARAR 5m7h A 3.15 BS02 GNP A 1 R183 P184 N185 V186 G187 K188 S189 S190 K236 N294 K295 D297 A298 S329 A330 L331 R171 P172 N173 V174 G175 K176 S177 S178 K221 N279 K280 D282 A283 S314 A315 L316 P50743 KPVVAIVGRPNVGKSTIFNRIAGERISEDTPDRIYSSAEWLNYDFNLIDTGGIGDEPFLAQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHFKNIPETKYNEEVIQFCLIGRPNVGKSSLVNAMLGEERVIVSNTTRDAVDTSFTYNQQEFVIVDTAGMRKKGKVYETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVDKDESTMKEFEENIRDHFQFLDYAPILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVSVKPPSFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIFARAR 5m7h A 3.15 BS03 PO4 A 2 G15 T18 K120 G13 T16 K110 P50743 KPVVAIVGRPNVGKSTIFNRIAGERISEDTPDRIYSSAEWLNYDFNLIDTGGIGDEPFLAQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHFKNIPETKYNEEVIQFCLIGRPNVGKSSLVNAMLGEERVIVSNTTRDAVDTSFTYNQQEFVIVDTAGMRKKGKVYETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVDKDESTMKEFEENIRDHFQFLDYAPILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVSVKPPSFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIFARAR 5m7w C 1.97 BS01 WZO C 1 M101 W102 E103 R157 K162 M70 W71 E72 R123 K128 P63073 EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSH 5m7z C 1.69 BS01 7LO C 1 M101 R157 M70 R114 P63073 EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTNRDAVTHVYKERLGLPP 5m80 A 2.12 BS01 7L2 A 1 F48 N50 K52 K54 W56 Q57 N59 M101 W102 E103 R157 K162 F18 N20 K22 K24 W26 Q27 N29 M71 W72 E73 R127 K132 P63073 PEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTAKNRFVV 5m81 A 1.90 BS01 7L2 A 1 F48 N50 K52 K54 W56 N59 M101 W102 E103 R157 K159 K162 K206 F20 N22 K24 K26 W28 N31 M73 W74 E75 R129 K131 K134 K178 P63073 ANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSTTKNRFVV 5m81 C 1.90 BS01 7L2 C 1 K52 K54 W56 N59 M101 W102 E103 R157 K162 W166 K21 K23 W25 N28 M70 W71 E72 R126 K131 W135 P63073 EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTKNRFVV 5m81 D 1.90 BS01 7L2 D 1 K52 K54 W56 N59 M101 W102 R157 K162 K21 K23 W25 N28 M70 W71 R126 K131 P63073 EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHKNRFVV 5m82 A 1.86 BS01 3CX A 1 Y500 R508 A523 G524 F525 Y61 R69 A84 G85 F86 P73184 SLQNIFRATSDEVRHLLSCDRVLVYRFNPDWSGEFIHESVAQMWEPLKDLQNNFPLWQDTYLQENEGGRYRNHESLAVGDVETAGFTDCHLDNLRRFEIRAFLTVPVFVGEQLWGLLGAYQNGAPRHWQAREIHLLHQIANQLGVAVYQAQLLARFQE 5m9x B 2.35 BS01 7KP B 1 D50 F53 Y132 P134 R135 R190 N192 A193 E232 H289 D290 I295 Q301 Y344 R399 D50 F53 Y132 P134 R135 R190 N192 A193 E232 H289 D290 I295 Q301 Y344 R399 2.4.1.7 A0ZZH6 29057405 MKNKVQLITYADRLGDGTIKSMTDILRTRFDGVYDGVHILPFFTPFDGADAGFDPIDHTKVDERLGSWDDVAELSKTHNIMVDAIVNHMSWESKQFQDVLAKGEESEYYPMFLTMSSVFPNGATEEDLAGIYRPRPGLPFTHYKFAGKTRLVWVSFTPQQVDIDTDSDKGWEYLMSIFDQMAASHVSYIRLNAVGYGAKEAGTSCFMTPKTFKLISRLREEGVKRGLEILIEVHSYYKKQVEIASKVDRVYDFALPPLLLHALSTGHVEPVAHWTDIRPNNAVTVLDTHDGIGVIDIGSDQLDRSLKGLVPDEDVDNLVNTIHANTHGESQAATGAAASNLDLYFVNSTYYSALGCNDQHYIAARAVQFFLPGVPQVYYVGALAGKNDMELLRKTNNGRDINRHYYSTAEIDENLKRPVVKALNALAKFRNELDAFDGTFSYTTDDDTSISFTWRGETSQATLTFEPKRGLGVDNTTPVAMLEWEDSAGDHRSDDLIANPPVVA 5mab A 2.44 BS01 HEC A 1 F53 P57 A58 C59 C62 H63 Y72 R73 L75 L77 S87 R93 I106 R110 L111 M230 P231 P232 F53 P57 A58 C59 C62 H63 Y72 R73 L75 L77 S87 R93 I106 R110 L111 M230 P231 P232 A3DTD8 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mab A 2.44 BS02 HEC A 2 N114 M116 P117 L118 F156 F162 P167 H168 C169 C172 H173 F182 H183 L185 A197 K220 H224 L225 R240 N114 M116 P117 L118 F156 F162 P167 H168 C169 C172 H173 F182 H183 L185 A197 K220 H224 L225 R240 A3DTD8 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mab A 2.44 BS03 HEC C 1 S6 Y9 A26 L30 S6 Y9 A26 L30 A3DTD8 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mab B 2.44 BS01 HEC A 1 S6 Y9 A26 S6 Y9 A26 A3DTD8 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mab B 2.44 BS02 HEC B 1 F53 P57 A58 C59 C62 H63 Y72 R73 S87 R93 I106 I107 R110 L111 M230 P231 P232 F53 P57 A58 C59 C62 H63 Y72 R73 S87 R93 I106 I107 R110 L111 M230 P231 P232 A3DTD8 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mab B 2.44 BS03 HEC B 2 N114 M116 P117 L118 F162 P167 H168 C169 C172 H173 F182 H183 A197 D198 V210 K220 H224 L225 R240 N114 M116 P117 L118 F162 P167 H168 C169 C172 H173 F182 H183 A197 D198 V210 K220 H224 L225 R240 A3DTD8 DTRTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5mab C 2.44 BS03 HEC C 2 N114 M116 P117 L118 F162 P167 H168 C169 C172 H173 F182 H183 L185 L187 A197 H224 L225 R240 N112 M114 P115 L116 F160 P165 H166 C167 C170 H171 F180 H181 L183 L185 A195 H222 L223 R238 A3DTD8 RTLSQQYLDDVRSGAIVIEGDSAAVSELILKRDIPIPYSYIAQLFATPNAFGSGPACIICHGSNNPTHAYRGLNLSTCDGLRNGSTEQPARAIFTPGEDPKNAIIGRRLRANRMPLGIAFNNPTDSAPILAIKEWILAGAPNDEHFTKEILPLFATDNTFGPDTPHCTTCHFSNQEPPSFHELNLTTYEGIMLGADSVAKGVDNATKVIIPGDPEASKVFQHLTEDRMPPGIDPSEDRDHPNTQILFAWIKQGAKCE 5man B 2.04 BS01 NGR B 1 D50 P134 R135 F156 N192 Y196 E232 V233 H234 H289 D290 R399 D50 P134 R135 F156 N192 Y196 E232 V233 H234 H289 D290 R399 2.4.1.7 A0ZZH6 29057405 MKNKVQLITYADRLGDGTIKSMTDILRTRFDGVYDGVHILPFFTPFDGADAGFDPIDHTKVDERLGSWDDVAELSKTHNIMVDAIVNHMSWESKQFQDVLAKGEESEYYPMFLTMSSVFPNGATEEDLAGIYRPRPGLPFTHYKFAGKTRLVWVSFTPQQVDIDTDSDKGWEYLMSIFDQMAASHVSYIRLNAVGYGAKEAGTSCFMTPKTFKLISRLREEGVKRGLEILIEVHSYYKKQVEIASKVDRVYDFALPPLLLHALSTGHVEPVAHWTDIRPNNAVTVLDTHDGIGVIDIGSDQLDRSLKGLVPDEDVDNLVNTIHANTHGESQAATGAAASNLDLYFVNSTYYSALGCNDQHYIAARAVQFFLPGVPQVYYVGALAGKNDMELLRKTNNGRDINRHYYSTAEIDENLKRPVVKALNALAKFRNELDAFDGTFSYTTDDDTSISFTWRGETSQATLTFEPKRGLGVDNTTPVAMLEWEDSAGDHRSDDLIANPPVVA 5maq A 2.46 BS01 ADP A 1 F91 G92 V93 P94 R106 R122 E126 D127 V130 V131 F91 G92 V93 P94 R106 R122 E126 D127 V130 V131 A0A0S7ASE9 MKKYRVQPDGRFELKRFDPDDTSAFEGGKQAALEALAVLNRRLEKLQELLYAEGQHKVLVVLQAMDAGGKDGTIRVVFDGVNPSGVRVASFGVPTEQELARDYLWRVHQQVPRKGELVIFNRSHYEDVLVVRVKNLVPQQVWQKRYRHIREFERMLADEGTTILKFFLHISKDEQRQRLQERLDNPEKRWKFRMGDLEDRRLWDRYQEAYEAAIRETSTEYAPWYVIPANKNWYRNWLVSHILVETLEGLAMQYPQP 5maq B 2.46 BS02 MG B 1 D66 D196 D66 D196 A0A0S7ASE9 MKKYRVQPDGRFELKRFDPDDTSAFEGGKQAALEALAVLNRRLEKLQELLYAEGQHKVLVVLQAMDAGGKDGTIRVVFDGVNPSGVRVASFGVPTEQELARDYLWRVHQQVPRKGELVIFNRSHYEDVLVVRVKNLVPQQVWQKRYRHIREFERMLADEGTTILKFFLHISKDEQRQRLQERLDNPEKRWKFRMGDLEDRRLWDRYQEAYEAAIRETSTEYAPWYVIPANKNWYRNWLVSHILVETLEGLAMQYPQ 5maq C 2.46 BS01 ADP C 1 F91 G92 V93 P94 R106 R122 E126 D127 V130 F91 G92 V93 P94 R106 R122 E126 D127 V130 A0A0S7ASE9 MKKYRVQPDGRFELKRFDPDDTSAFEGGKQAALEALAVLNRRLEKLQELLYAEGQHKVLVVLQAMDAGGKDGTIRVVFDGVNPSGVRVASFGVPTEQELARDYLWRVHQQVPRKGELVIFNRSHYEDVLVVRVKNLVPQQVWQKRYRHIREFERMLADEGTTILKFFLHISKDEQRQRLQERLDNPEKRWKFRMGDLEDRRLWDRYQEAYEAAIRETSTEYAPWYVIPANKNWYRNWLVSHILVETLEGLAMQYPQPE 5maq D 2.46 BS01 ADP D 1 D66 F91 G92 V93 P94 R106 R122 E126 D127 V130 D66 F91 G92 V93 P94 R106 R122 E126 D127 V130 A0A0S7ASE9 MKKYRVQPDGRFELKRFDPDDTSAFEGGKQAALEALAVLNRRLEKLQELLYAEGQHKVLVVLQAMDAGGKDGTIRVVFDGVNPSGVRVASFGVPTEQELARDYLWRVHQQVPRKGELVIFNRSHYEDVLVVRVKNLVPQQVWQKRYRHIREFERMLADEGTTILKFFLHISKDEQRQRLQERLDNPEKRWKFRMGDLEDRRLWDRYQEAYEAAIRETSTEYAPWYVIPANKNWYRNWLVSHILVETLEGLAMQYPQPIVIE 5mau A 1.30 BS01 HEM A 1 I59 R60 Y61 A62 L70 I90 K92 W96 F108 H114 T115 G118 L119 L122 V125 R127 L129 F141 T143 F145 F155 L158 L159 M162 E167 W168 E174 I50 R51 Y52 A53 L61 I81 K83 W87 F99 H105 T106 G109 L110 L113 V116 R118 L120 F132 T134 F136 F146 L149 L150 M153 E158 W159 E165 B8HNS6 NNRYSFIGGRTGQWQVVKIRNVLGPGLQLVEKVNILNGSAWRLQGFASNIRYAIRTELEALQAVQPMLNRAEAILAVLIPIKKSAQWWEMAQDERRDIFERESHHTAVGLEYLPGVARRLLHCRDLGEEFDFLTWFEFAPEHSSAFNELLLRMRASKEWEYVEREVEVWLKRL 5may A 1.65 BS02 CA A 2 E95 D96 D99 D101 D104 E95 D96 D99 D101 D104 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5may A 1.65 BS04 PK6 A 1 S22 A23 G24 D96 S97 S22 A23 G24 D96 S97 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5may B 1.65 BS04 PK6 B 1 S22 A23 G24 R72 D96 S22 A23 G24 R72 D96 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5may C 1.65 BS04 PK6 C 1 S22 A23 G24 D96 S22 A23 G24 D96 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5maz A 1.45 BS04 IGF A 1 S22 G24 D96 S97 S22 G24 D96 S97 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5maz B 1.45 BS02 IGF B 1 S22 A23 G24 V69 D96 S97 S22 A23 G24 V69 D96 S97 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5maz C 1.45 BS04 IGF C 1 S22 G24 V69 N70 R72 D96 S97 S22 G24 V69 N70 R72 D96 S97 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5maz D 1.45 BS02 IGF D 1 S22 G24 V69 D96 S97 S22 G24 V69 D96 S97 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5mb0 A 1.15 BS01 47V A 1 D35 Y79 D81 S83 S115 F116 G221 D35 Y79 D81 S83 S115 F116 G221 3.4.23.22 P11838 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 5mb0 A 1.15 BS02 F91 A 1 D35 Y79 D81 F116 L125 G221 D35 Y79 D81 F116 L125 G221 3.4.23.22 P11838 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 5mb0 A 1.15 BS04 F63 A 1 D11 D15 A16 S115 D119 I122 T223 D11 D15 A16 S115 D119 I122 T223 3.4.23.22 P11838 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 5mb1 A 1.65 BS04 7KT A 1 S22 A23 G24 V69 R72 D96 S97 S22 A23 G24 V69 R72 D96 S97 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5mb1 C 1.65 BS01 CA C 1 N21 D99 D101 N103 D104 N21 D99 D101 N103 D104 A0A0H2ZE85 ATQGVFTLPANTQFGVTAFANSAGTQTVNVQVNNETVATFTGQSTNNAIIGSKVLNSGGGGKVQILVSVNGRSSDLVSAQVILANELNFALVGSEDSTDNDYNDAVVVINWPLG 5mb3 A 1.05 BS01 5GL A 1 D15 G250 F280 F291 Q295 D15 G250 F280 F291 Q295 3.4.23.22 P11838 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 5mb7 A 1.30 BS01 4AV A 1 D33 Y79 D81 S83 S115 F116 D119 I122 G221 D33 Y79 D81 S83 S115 F116 D119 I122 G221 3.4.23.22 P11838 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 5mbs A 3.20 BS01 GDP A 1 P184 N185 V186 G187 K188 S189 S190 K236 K295 P164 N165 V166 G167 K168 S169 S170 K207 K266 A0A164XD11 KPVVAIVGRPNVGKSTIFNRIAERISIVEDTPDRIYSSAEWLNYDFNLIDTGQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHFKNIPETKYNEEVIQFCLIGRPNVGKSSLVNAMLGEERVIVAVDTSFTYNQQEFVIVDTAGMRKKGKVYETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVDSTMKEFEENIRDHFQFLDYAPILFMSALTKKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVSVKPPSFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIFARAR 5mby A 1.55 BS03 GLY A 1 Y241 I244 D276 D287 H377 Y236 I239 D271 D282 H372 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECQVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDAFTPFS 5mby B 1.55 BS03 GLY B 1 Y241 I244 H255 D276 D287 H377 Y236 I239 H250 D271 D282 H372 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECQVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDAFTPF 5mbz A 1.50 BS03 GLY A 1 D276 D287 H370 H377 D268 D279 H362 H369 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKIFSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5mbz A 1.50 BS04 PRO A 1 H255 H366 H377 R398 E412 H247 H358 H369 R390 E404 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKIFSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5mbz B 1.50 BS02 MN B 2 D276 D287 T289 E412 E452 D266 D277 T279 E402 E442 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKIFSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSCICGSGENSAVLHYAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTP 5mc1 A 1.43 BS02 GLY A 1 N276 D287 H370 H377 N271 D282 H365 H372 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFNMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPF 5mc2 A 1.70 BS02 GLY A 1 I244 D276 D287 H370 H377 I237 D265 D276 H359 H366 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYICGSGENSAVLHYAPNDRTIQNGDMCLFDMDGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFT 5mc2 B 1.70 BS03 PRO B 1 H366 H377 R398 E412 R450 H357 H368 R389 E403 R441 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYICGSGSAVLHYGHAGAPNDRTIQNGDMCLFDMDGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTP 5mc3 A 1.52 BS01 MN A 1 Y241 D276 D287 T289 K412 E452 Y236 D271 D282 T284 K407 E447 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVKPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCAFTPF 5mc3 A 1.52 BS02 GLY A 1 Y241 I244 H255 D276 H377 K412 Y236 I239 H250 D271 H372 K407 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVKPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCAFTPF 5mc3 A 1.52 BS03 PRO A 1 L254 H255 H366 H377 R398 K412 R450 L249 H250 H361 H372 R393 K407 R445 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVKPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCAFTPF 5mc4 A 1.80 BS04 PRO A 1 H366 H377 R398 E412 H348 H359 R380 E394 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGRVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCD 5mc4 B 1.80 BS03 GLY B 1 Y241 D276 D287 H370 H377 Y233 D262 D273 H356 H363 3.4.13.9 P12955 GPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGRVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFT 5mg5 C 3.44 BS01 13X C 1 H56 N87 C88 Y124 I128 H144 Y298 L300 H347 S349 H53 N84 C85 Y121 I125 H141 Y295 L297 H344 S346 Q4K420 RRVAIVSAAYTPKPGSSRVRQTFKEMIVESAYKALKDAKMHPREIQAVAYGYHGEGISEYGGLGPTISDALGISPAPTFMSTANCTSSSVSFQMGHQMVASGEYDIVLCGGFEKMTDHFNYAEYIGSSTECEYDYFLGISHTDAFALATAEYFQKFGYAGREADVLATFGRQMRIYAQNTPTATRYGQPIPSLEVLKNSEACGSMLAWGEASGCAILVAEHLAHKYTDKPVFVRGCAYTGVSHYFGTRFHNPTLHHPGLPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGAGLIQMESMGICGKGQAGDFVLEGGIALDGQLPLNTDGGNIGRGHASGCDGILHITELFRQLRGESDNQVKGARIGVSQNLGGYAAHNSVIVLSND 5mg5 L 3.44 BS01 13X L 1 H56 C88 Y124 I128 H144 H347 S349 H54 C86 Y122 I126 H142 H345 S347 Q4K420 ARRVAIVSAAYTPKPGSSRVRQTFKEMIVESAYKALKDAKMHPREIQAVAYGYHGEGISEYGGLGPTISDALGISPAPTFMSTANCTSSSVSFQMGHQMVASGEYDIVLCGGFEKMTDHFNYAEYIGSSTECEYDYFLGISHTDAFALATAEYFQKFGYAGREADVLATFGRQMRIYAQNTPTATRYGQPIPSLEVLKNSEACGSMLAWGEASGCAILVAEHLAHKYTDKPVFVRGCAYTGVSHYFGTRFHNPTLHHPGLPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGAGLIQMESMGICGKGQAGDFVLEGGIALDGQLPLNTDGGNIGRGHASGCDGILHITELFRQLRGESDNQVKGARIGVSQNLGGYAAHNSVIVLSND 5mg5 O 3.44 BS01 13X O 1 H56 C88 Y124 I128 H144 F148 W211 H347 H54 C86 Y122 I126 H142 F146 W209 H345 Q4K420 ARRVAIVSAAYTPKPGSSRVRQTFKEMIVESAYKALKDAKMHPREIQAVAYGYHGEGISEYGGLGPTISDALGISPAPTFMSTANCTSSSVSFQMGHQMVASGEYDIVLCGGFEKMTDHFNYAEYIGSSTECEYDYFLGISHTDAFALATAEYFQKFGYAGREADVLATFGRQMRIYAQNTPTATRYGQPIPSLEVLKNSEACGSMLAWGEASGCAILVAEHLAHKYTDKPVFVRGCAYTGVSHYFGTRFHNPTLHHPGLPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGAGLIQMESMGICGKGQAGDFVLEGGIALDGQLPLNTDGGNIGRGHASGCDGILHITELFRQLRGESDNQVKGARIGVSQNLGGYAAHNSVIVLSND 5mg5 R 3.44 BS01 13X R 1 H56 C88 I128 H144 F148 Y298 H347 S349 H53 C85 I125 H141 F145 Y295 H344 S346 Q4K420 RRVAIVSAAYTPKPGSSRVRQTFKEMIVESAYKALKDAKMHPREIQAVAYGYHGEGISEYGGLGPTISDALGISPAPTFMSTANCTSSSVSFQMGHQMVASGEYDIVLCGGFEKMTDHFNYAEYIGSSTECEYDYFLGISHTDAFALATAEYFQKFGYAGREADVLATFGRQMRIYAQNTPTATRYGQPIPSLEVLKNSEACGSMLAWGEASGCAILVAEHLAHKYTDKPVFVRGCAYTGVSHYFGTRFHNPTLHHPGLPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGAGLIQMESMGICGKGQAGDFVLEGGIALDGQLPLNTDGGNIGRGHASGCDGILHITELFRQLRGESDNQVKGARIGVSQNLGGYAAHNSVIVLSND 5mhf A 2.10 BS01 6A9 A 1 P436 F440 F441 R443 F445 W447 D448 G578 D580 Y746 W747 W822 P349 F353 F354 R356 F358 W360 D361 G491 D493 Y659 W660 W735 3.2.1.106 Q80UM7 LAWLRVRRALTLHPAPSALPPDSSSPAVAPELFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGATPGTPPKLRHTCEQGDGVGPYGWEFHDGRTFGRQHIHDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQASFPLVSLFFYVVTDGQEVLLPEIQLKSISGHTSELGDFRLTLLPPTSPGDTVPKHGSYNVFWSSNPGLPQLTDMVKSRLNSWFQHRPPGASPDRYLGLPGSLKWEESGQGQFLIQQVTLKAPFSVEFVFESGSAARLVGSQLTQALESHAAAFKERFEKTFQLKEKGLSPEEQALGQVALSGLLGGIGYFYGQGLVLPDTMDPALFPPVPLFSGVPSRSFFPRGFLWDEGFHQLVVQRWDPHLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAAHANPPTLLLPVVHMLEGHDPDDLAFLRKAFPRLHAWFSWLHQSQAGPVPLSYRWRGRDLALPTLLNPKTLPSGLDDYPRASHPSTAERHLDLRCWVALGARVLSQLAEQLGETEAAAELGPLAASLEEPGSLDELHWAPELGVFADFGNHTKAVQLKSRPPQGLVRVVGRPPPRLQYVDALGYVSLFPLLLQLLDPSSPRLGPLLDVLADSRHLWSPFGLRSLSASSLFYKQRNTEHDPPYWRGAVWLNINYLALGALHHYGHVEGPHKVQAAKLYHELRANVVRNVRQQYQATGFLWEQYSDQDGRGMGCRPFQGWTSLVLLIMAEEYASWS 5mhf D 2.10 BS01 6A9 D 1 P436 S439 F440 F441 R443 F445 W447 D448 G578 D580 Y746 W747 W822 P366 S369 F370 F371 R373 F375 W377 D378 G508 D510 Y676 W677 W752 3.2.1.106 Q80UM7 ETGWVLAWLRVRRALTLHPAPSALPPDSSSPAVAPELFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGATPGTPPKLRHTCEQGDGVGPYGWEFHDGRTFGRQHIHDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQASGTPSFPLVSLFFYVVTDGQEVLLPEIQLKSISGHTSELGDFRLTLLPPTSPGDTVPKHGSYNVFWSSNPGLPQLTDMVKSRLNSWFQHRPPGASPDRYLGLPGSLKWEESGQGQFLIQQVTLKAPFSVEFVFESGSAATGGNQASGRLVGSQLTQALESHAAAFKERFEKTFQLKEKGLSPEEQALGQVALSGLLGGIGYFYGQGLVLPDTMDPALFPPVPLFSGVPSRSFFPRGFLWDEGFHQLVVQRWDPHLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAAHANPPTLLLPVVHMLEGHDPDDLAFLRKAFPRLHAWFSWLHQSQAGPVPLSYRWRGRDLALPTLLNPKTLPSGLDDYPRASHPSTAERHLDLRCWVALGARVLSQLAEQLGETEAAAELGPLAASLEEPGSLDELHWAPELGVFADFGNHTKAVQLKSRPPQGLVRVVGRPPPRLQYVDALGYVSLFPLLLQLLDPSSPRLGPLLDVLADSRHLWSPFGLRSLSASSLFYKQRNTEHDPPYWRGAVWLNINYLALGALHHYGHVEGPHKVQAAKLYHELRANVVRNVRQQYQATGFLWEQYSDQDGRGMGCRPFQGWTSLVLLIMAEEYASW 5mhi A 1.49 BS01 III B 1 Q84 H87 E127 F129 S130 R133 D166 K168 P169 E170 F187 T197 L198 C199 G200 T201 P202 E203 Y204 E230 P236 F239 A240 D241 Y247 D328 Y330 Q85 H88 E128 F130 S131 R134 D167 K169 P170 E171 F188 T198 L199 C200 G201 T202 P203 E204 Y205 E231 P237 F240 A241 D242 Y248 D329 Y331 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5mhi A 1.49 BS02 7N9 A 1 L49 V57 A70 M120 E121 V123 E127 L173 T183 F327 L50 V58 A71 M121 E122 V124 E128 L174 T184 F328 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5mhi A 1.49 BS03 7N9 A 2 G136 A233 Y235 G137 A234 Y236 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5mhl A 2.40 BS01 III K 1 W279 Q313 C314 I352 T365 S368 V369 W370 N371 Y372 H373 L439 H459 W265 Q299 C300 I338 T351 S354 V355 W356 N357 Y358 H359 L425 H439 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQ 5mhl B 2.40 BS01 III O 1 Y214 W279 Q313 C314 T365 D367 S368 V369 W370 N371 Y372 H373 Y441 Y200 W265 Q299 C300 T351 D353 S354 V355 W356 N357 Y358 H359 Y427 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGRSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQRRPS 5mhl B 2.40 BS03 CA B 2 N436 A457 E485 E490 R491 N422 A438 E466 E471 R472 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGRSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQRRPS 5mhm A 2.12 BS01 III H 1 Y214 R223 W279 C314 W315 F339 M350 I352 V360 T365 D367 S368 V369 W370 N371 Y372 H373 T398 L439 Y200 R209 W265 C300 W301 F325 M336 I338 V340 T345 D347 S348 V349 W350 N351 Y352 H353 T378 L419 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYIVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQ 5mhn A 2.48 BS01 III H 1 Y214 R223 W279 Q313 C314 W315 F339 M350 I352 T365 D367 S368 V369 W370 N371 Y372 H373 T398 L439 Y441 Y200 R209 W265 Q299 C300 W301 F325 M336 I338 T346 D348 S349 V350 W351 N352 Y353 H354 T379 L420 Y422 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 5mhn A 2.48 BS04 CA A 3 N436 A457 T458 K482 E485 E490 N417 A434 T435 K459 E462 E467 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 5mhn B 2.48 BS01 III I 1 Y214 R223 W279 C314 W315 F339 M350 I352 S368 V369 W370 N371 Y372 H373 T398 L439 Y441 Y200 R209 W265 C300 W301 F325 M336 I338 S349 V350 W351 N352 Y353 H354 T379 L420 Y422 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 5mho A 2.92 BS01 III G 1 Y214 R223 W279 C314 W315 I352 D367 V369 W370 N371 Y372 H373 T398 Q400 Y200 R209 W265 C300 W301 I338 D347 V349 W350 N351 Y352 H353 T378 Q380 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYIHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPRKLIASMSSDSLRHVYGELDVQI 5mho A 2.92 BS02 CA A 1 A264 N267 K269 D270 D271 Y407 A250 N253 K255 D256 D257 Y387 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYIHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPRKLIASMSSDSLRHVYGELDVQI 5mho B 2.92 BS01 III H 1 W279 C314 W315 M350 I352 D367 S368 V369 W370 N371 Y372 H373 T398 Q400 L439 Y441 W265 C300 W301 M336 I338 D347 S348 V349 W350 N351 Y352 H353 T378 Q380 L419 Y421 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWRKLIASMSSDSLRHVYGELDVQI 5mho B 2.92 BS04 CA B 3 N436 D438 A457 T458 E485 E490 N416 D418 A431 T432 E459 E464 2.3.2.13 P00488 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWRKLIASMSSDSLRHVYGELDVQI 5mhq A 1.30 BS01 8QT A 1 I10 G11 V18 A31 K33 F80 E81 L83 H84 Q85 K89 Q131 N132 L134 A144 D145 I13 G14 V21 A34 K36 F74 E75 L77 H78 Q79 K83 Q125 N126 L128 A138 D139 2.7.11.22 P24941 PEFMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 5mi3 B 2.80 BS01 GDP B 1 D22 G24 K25 T26 T27 F47 N136 K137 D139 M140 S174 A175 L176 D14 G16 K17 T18 T19 F39 N128 K129 D131 M132 S166 A167 L168 A8A5E6 TKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG 5mi9 A 3.30 BS01 GDP A 1 H20 D22 H23 G24 K25 T26 T27 F47 K137 S174 A175 L176 H12 D14 H15 G16 K17 T18 T19 F39 K129 S166 A167 L168 A8A5E6 TKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGIEINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSICGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVL 5mi9 B 3.30 BS01 GDP B 1 H20 V21 D22 H23 G24 K25 T26 T27 F47 N136 K137 D139 S174 A175 L176 H12 V13 D14 H15 G16 K17 T18 T19 F39 N122 K123 D125 S160 A161 L162 A8A5E6 TKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKANTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSICGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVL 5min A 1.76 BS03 CA A 3 Y343 A350 L376 R406 Y343 A350 L376 R406 1.1.5.2 P13650 DVPLTPSQFAKAKSENFDKKVILSNLNKPHALLWGPDNQIWLTERATGKILRVNPESGSVKTVFQVPEIVNDADGQNGLLGFAFHPDFKNNPYIYISGTFKNPKSTDKALPNQTIIRRYTYNKSTDTLEKPVDLLAGLPSSKDHQSGRLVIGPDQKIYYTIGDQGRNQLAYLFLPNQAQHTPTQQELNGKDYHTYMGKVLRLNLDGSIPKDNPSFNGVVSHIYTLGHRNPQGLAFTPNGKLLQSEQGPNSDDEINLIVKGGNYGWPNVAGYKDDSGYAYANYSAAANKSIKDLAQNGVKVAAGVPVTKESEWTGKNFVPPLKTLYTVQDTYNYNDPTCGEMTYICWPTVAPSSAYVYKGGKKAITGWENTLLVPSLKRGVIFRIKLDPTYSTTYDDAVPMFKSNNRYRDVIASPDGNVLYVLTDTAGNVQKDDGSVTNTLENPGSLIKFTYK 5min B 1.76 BS03 CA B 3 H193 T194 H193 T194 1.1.5.2 P13650 DVPLTPSQFAKAKSENFDKKVILSNLNKPHALLWGPDNQIWLTERATGKILRVNPESGSVKTVFQVPEIVNDADGQNGLLGFAFHPDFKNNPYIYISGTFKNPKSTDKALPNQTIIRRYTYNKSTDTLEKPVDLLAGLPSSKDHQSGRLVIGPDQKIYYTIGDQGRNQLAYLFLPNQAQHTPTQQELNGKDYHTYMGKVLRLNLDGSIPKDNPSFNGVVSHIYTLGHRNPQGLAFTPNGKLLQSEQGPNSDDEINLIVKGGNYGWPNVAGYKDDSGYAYANYSAAANKSIKDLAQNGVKVAAGVPVTKESEWTGKNFVPPLKTLYTVQDTYNYNDPTCGEMTYICWPTVAPSSAYVYKGGKKAITGWENTLLVPSLKRGVIFRIKLDPTYSTTYDDAVPMFKSNNRYRDVIASPDGNVLYVLTDTAGNVQKDDGSVTNTLENPGSLIKFTYKA 5miw A 1.28 BS01 URA A 1 T94 G95 F161 Q165 R167 F194 E195 M196 T93 G94 F160 Q164 R166 F193 E194 M195 2.4.2.3 Q9K4U1 TKTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5miw C 1.28 BS01 URA C 1 T93 T94 G95 F161 Q165 R167 E195 M196 T91 T92 G93 F159 Q163 R165 E193 M194 2.4.2.3 Q9K4U1 KTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5mjc A 1.62 BS02 OXY A 1 L113 W133 L136 Y137 V140 L111 W131 L134 Y135 V138 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5mjd A 1.70 BS01 HEM A 1 L38 L41 F42 Y44 H64 K67 V68 V71 L92 H96 V101 F106 V109 L36 L39 F40 Y42 H62 K65 V66 V69 L90 H94 V99 F104 V107 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5mjd A 1.70 BS02 OXY A 1 W133 L136 Y137 W131 L134 Y135 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5mjs A 4.60 BS01 GDP A 1 G10 Q11 C12 N99 G140 G141 G142 T143 G144 D177 N204 Y222 G10 Q11 C12 N99 G140 G141 G142 T143 G144 D177 N204 Y222 P05219 29235477 MREIVHIQAGQCGNQVGAAFWSTIADEHGLDSAGIYHGTSEAQHERLNVYFNEAAGGKYVPRAVLVDLEPGTMDAVKSGKFGNLFRPDNIIYGQSGAGNIWAKGHYTEGAELADAVLDVVRREAEACDALQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRMMATFSVAPAPKSSDTVVEPYNATLSMHQLVENSDETFCIDNEALSSIFANTLKIKSPSYDDLNHLVSAVMAGVTTSFRFPGELNSDLRKLAVNMVPFPRHFFMVGFAPLAAIGSSSFQAVSVPELTQQMFDANNMMVAADPRHGRYLTVAALFRGKVSMKEVDEQIRSVQTKNSAYFVEWIPDNVLKAVCSVPPKDLKMSATFIGNSTSIQEIFRRLGDQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEAG 5mjs E 4.60 BS01 GTP E 1 G10 Q11 A12 Q15 S104 S144 G146 G147 G148 T149 G150 T183 N210 Y228 N232 G10 Q11 A12 Q15 S94 S134 G136 G137 G138 T139 G140 T173 N200 Y218 N222 P04688 29235477 MREVISVHVGQAGVQIGNACWELYCLEHGIGPDGFPTELNDGFGTFFSETGQGKFVPRSIYVDLEPNVIDQVRTGPYKDLFHPEQMVTGKEDASNNYARGHYTVGKEMIDSVLERIRRMADNCSGLQGFLVFHSFGGGTGSGLGALLLERLNMEYGKKSNLQFSVYPAPQVSTSVVEPYNSVLTTHATLDNSDCTFMVDNEACYDICRRNLDIERPTYENLNRLIAQVVSSITASLRFAGSLNVDLNEFQTNLVPYPRIHFPLVTYSPIVSAAKAFHESNSVQEITNQCFEPYNQMVKCDPRTGRYMATCLLYRGDVIPRDVQAAVTSIKSRRTIQFVDWCPTGFKIGICYEPPQHVPGSGIAKVNRAVCMLSNTTSIAEAWSRLDHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALERDYEEVGQDSM 5mjs B 4.60 BS01 GDP B 1 G10 Q11 C12 N99 S138 G140 G141 G142 T143 G144 D177 N204 Y222 N226 G10 Q11 C12 N99 S138 G140 G141 G142 T143 G144 D177 N204 Y222 N226 P05219 29235477 MREIVHIQAGQCGNQVGAAFWSTIADEHGLDSAGIYHGTSEAQHERLNVYFNEAAGGKYVPRAVLVDLEPGTMDAVKSGKFGNLFRPDNIIYGQSGAGNIWAKGHYTEGAELADAVLDVVRREAEACDALQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRMMATFSVAPAPKSSDTVVEPYNATLSMHQLVENSDETFCIDNEALSSIFANTLKIKSPSYDDLNHLVSAVMAGVTTSFRFPGELNSDLRKLAVNMVPFPRHFFMVGFAPLAAIGSSSFQAVSVPELTQQMFDANNMMVAADPRHGRYLTVAALFRGKVSMKEVDEQIRSVQTKNSAYFVEWIPDNVLKAVCSVPPKDLKMSATFIGNSTSIQEIFRRLGDQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEAG 5mjt H 1.40 BS01 III D 1 F34 K36 Q38 L40 L65 R67 R73 T74 R75 Y76 K81 I82 F19 K21 Q24 L26 L60 R62 R68 T69 R70 Y71 K77 I78 3.4.21.5 P00734 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDSCEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 5mjt H 1.40 BS02 23U H 1 H57 Y60A W60D E97A N98 L99 I174 S190 C191 S195 V213 S214 W215 G216 E217 G219 G226 F227 H43 Y47 W50 E94 N95 L96 I172 S193 C194 S198 V218 S219 W220 G221 E222 G223 G231 F232 3.4.21.5 P00734 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDSCEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 5mki C 2.05 BS01 CA C 1 N18 L72 N16 L70 A6UPF5 DTQRPLDALGKSINTNVTVYLKDGKLVKGRLKAYDLHMNVALENAKIESDEEKEFPMLVVRGDNVLYVSL 5mki D 2.05 BS01 CA D 1 H39 N41 R63 H37 N39 R58 A6UPF5 DTQRPLDALGKSINTNVTVYLKDGKLVKGRLKAYDLHMNVALENAKIEEKEFPMLVVRGDNVLYVSL 5mki F 2.05 BS01 CA F 1 H39 R63 H37 R61 A6UPF5 DTQRPLDALGKSINTNVTVYLKDGKLVKGRLKAYDLHMNVALENAKIESDEEKEFPMLVVRGDNVLYVSL 5mki K 2.05 BS01 CA K 1 N41 R63 N39 R61 A6UPF5 DTQRPLDALGKSINTNVTVYLKDGKLVKGRLKAYDLHMNVALENAKIESDEEKEFPMLVVRGDNVLYVSL 5mkn A 2.55 BS01 U5P A 1 H39 N41 R63 D65 H38 N40 R62 D64 A6UPF5 MDTQRPLDALGKSINTNVTVYLKDGKLVKGRLKAYDLHMNVALENAKIESDEEKEFPMLVVRGDNVLYVSL 5mkn A 2.55 BS02 U5P B 1 L38 M40 L37 M39 A6UPF5 MDTQRPLDALGKSINTNVTVYLKDGKLVKGRLKAYDLHMNVALENAKIESDEEKEFPMLVVRGDNVLYVSL 5mkn F 2.55 BS02 U5P F 2 R6 P7 L8 L38 R5 P6 L7 L37 A6UPF5 MDTQRPLDALGKSINTNVTVYLKDGKLVKGRLKAYDLHMNVALENAKIESDEEKEFPMLVVRGDNVLYVSL 5mkn J 2.55 BS01 U5P J 1 H39 N41 R63 G64 D65 H38 N40 R62 G63 D64 A6UPF5 MDTQRPLDALGKSINTNVTVYLKDGKLVKGRLKAYDLHMNVALENAKIESDEEKEFPMLVVRGDNVLYVSL 5mkn R 2.55 BS02 U5P d 1 L38 H39 M40 L37 H38 M39 A6UPF5 MDTQRPLDALGKSINTNVTVYLKDGKLVKGRLKAYDLHMNVALENAKIESDEEKEFPMLVVRGDNVLYVSL 5mkx A 1.68 BS01 82I A 1 P747 F748 V752 E756 A757 Y802 N803 Y809 P22 F23 V27 E31 A32 Y77 N78 Y84 2.3.1.48 Q92831 DQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLID 5mkx B 1.68 BS01 82I B 1 P747 F748 V752 A757 Y802 N803 Y809 P23 F24 V28 A33 Y78 N79 Y85 2.3.1.48 Q92831 PDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLID 5mky A 1.67 BS01 I0D A 1 F44 F45 F47 P48 V49 I53 A54 Y99 N100 Y106 F23 F24 F26 P27 V28 I32 A33 Y78 N79 Y85 Q9H8M2 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMS 5mky A 1.67 BS02 I0D A 2 L28 H31 F32 M121 S122 L7 H10 F11 M100 S101 Q9H8M2 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMS 5mkz A 1.62 BS01 RNK A 1 W81 F83 V87 L92 Y139 N140 I146 W40 F42 V46 L51 Y98 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 5ml0 A 1.64 BS01 P2L A 1 P746 F747 P750 E755 Y759 Y801 N802 Y808 P23 F24 P27 E32 Y36 Y78 N79 Y85 2.3.1.48 Q9JHD1 PEQLYSTLKNILQQVKNHPNAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLRNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCASILEKFFFSKIKEAGLIDK 5mld C 1.70 BS01 8DP B 1 E105 N108 E104 N107 K4REZ6 ALKALILNTTLRRSPSRSQTQGLIDKAVPLYEKEGIETEVVRVIDHDIEQEYWDDYDDWNAGEKARREDEWPWLLEKIREADILVIATPITLNMCTSAAHVILEKLNLMDELNGDTKQFPLYNKVAGLLMCGNEDGAHHVAGTVLNNLGRLGYSVPPNAAAYWLGPAGTGPGYIEGKGDRHFHTNKLIRFMVANTSHLARMLQETPYTTDLEACAQAAREESDDVFAIRVNVNTPAIRYKRFQKLGEVKVEE 5mld F 1.70 BS02 8DP G 1 E105 L109 E104 L108 K4REZ6 ALKALILNTTLRRSPSRSQTQGLIDKAVPLYEKEGIETEVVRVIDHDIEQEYWDDYDDWNAGEKARREDEWPWLLEKIREADILVIATPITLNMCTSAAHVILEKLNLMDELNGDTKQFPLYNKVAGLLMCGNEDGAHHVAGTVLNNLGRLGYSVPPNAAAYWLGPAGTGPGYIEGKGDRHFHTNKLIRFMVANTSHLARMLQETPYTTDLEACAQAAREESDDVFAIRVNVNTPAIRYKRFQKLGEVKVEE 5mli A 1.63 BS01 82I A 1 P82 F83 V87 L92 L94 Y139 N140 I146 P41 F42 V46 L51 L53 Y98 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 5mlj A 1.80 BS01 9ST A 1 W751 P752 F753 P756 V757 E761 Y807 N808 Y814 W23 P24 F25 P28 V29 E33 Y79 N80 Y86 2.3.1.48 Q92830 DPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 5mlj B 1.80 BS01 9ST B 1 W751 P752 F753 P756 V757 E761 A762 Y765 Y807 N808 Y814 W22 P23 F24 P27 V28 E32 A33 Y36 Y78 N79 Y85 2.3.1.48 Q92830 PDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGG 5mln A 1.60 BS01 NAP A 1 G11 S13 R14 G15 I16 S35 R36 S37 L62 D63 L64 N89 A90 G91 V112 I142 S143 S144 Y157 K161 P187 G188 Y189 T190 T192 M194 T195 G7 S9 R10 G11 I12 S31 R32 S33 L58 D59 L60 N85 A86 G87 V108 I138 S139 S140 Y153 K157 P183 G184 Y185 T186 T188 M190 T191 B8K244 SNALVTGGSRGIGAASAIKLAQEGYNVTLASRSVDKLNEVKAKLPIVQDGQKHYIWELDLADVEAASSFKGAPLPARSYDVFVSNAGVAAFSPTADHDDKEWQNLLAVNLSSPIALTKALLKDVSERPVDKPLQIIYISSVAGLHGAAQVAVYSASKAGLDGFMRSVAREVGPKGIHVNSINPGYTKTEMTAGIEALPDLPIKGWIEPEAIADAVLFLAKSKNITGTNIVVDNGLIA 5mls H 1.62 BS01 III L 1 E23 I24 G25 M26 P28 W29 S115 D116 Y117 H119 P120 V121 C122 G133 Y134 K135 G136 R137 N159 Y184A M201 K202 P204 N204B N205 R206 W207 E8 I9 G10 M11 P13 W14 S112 D113 Y114 H116 P117 V118 C119 G133 Y134 K135 G136 R137 N157 Y183 M204 K205 P207 N209 N210 R211 W212 3.4.21.5 P00734 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDSCEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 5mls H 1.62 BS03 22U H 1 H57 Y60A W60D E97A N98 I174 S190 C191 S195 V213 S214 W215 G216 G226 F227 H43 Y47 W50 E94 N95 I172 S193 C194 S198 V218 S219 W220 G221 G231 F232 3.4.21.5 P00734 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDSCEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 5mm6 H 1.29 BS03 32U H 1 H57 Y60A W60D E97A N98 L99 I174 D189 S190 E192 S195 V213 S214 W215 G216 G219 G226 H43 Y47 W50 E94 N95 L96 I172 D192 S193 E195 S198 V218 S219 W220 G221 G223 G231 3.4.21.5 P00734 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDSCEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG 5mme A 1.35 BS01 8Q6 A 1 L1109 P1110 Q1113 V1115 L1120 N1168 R1173 V1174 F1177 L31 P32 Q35 V37 L42 N90 R95 V96 F99 2.3.1.48 Q92793 SMRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 5mmg A 1.23 BS01 UT0 A 1 L1109 P1110 Q1113 V1115 L1120 I1122 N1168 R1173 V1174 L27 P28 Q31 V33 L38 I40 N86 R91 V92 2.3.1.48 Q92793 KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 5mmv B 2.15 BS01 WE0 A 1 V338 S339 W340 R341 H342 R383 V21 S22 W23 R24 H25 R66 3.4.22.36 P29466 IKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH 5mxc A 1.14 BS01 MFU A 1 R24 E36 I76 Y92 W97 R24 E36 I76 Y92 W97 P18891 29232414 PTEFLYTSKIAAISWAATGGRQQRVYFQDLNGKIREAQRGGDNPWTGGSSQNVIGEAKLFSPLAAVTWKSAQGIQIRVYCVNKDNILSEFVYDGSKWITGQLGSVGVKVGSNSKLAALQWGGSESAPPNIRVYYQKSNGSGSSIHEYVWSGKWTAGASFGSTVPGTGIGATAIGPGRLRIYYQATDNKIREHCWDSNSWYVGGFSASASAGVSIAAISWGSTPQIRVYWQKGREELYEAAYGGSWNTPGQIKDASRPTPSLPDTFIAANSSGNIDISVFFQASGVSLQQWQWISGKGWSIGAVVPTGTPAGWL 5mxc A 1.14 BS03 MFU A 3 R131 E146 L178 W194 W199 R131 E146 L178 W194 W199 P18891 29232414 PTEFLYTSKIAAISWAATGGRQQRVYFQDLNGKIREAQRGGDNPWTGGSSQNVIGEAKLFSPLAAVTWKSAQGIQIRVYCVNKDNILSEFVYDGSKWITGQLGSVGVKVGSNSKLAALQWGGSESAPPNIRVYYQKSNGSGSSIHEYVWSGKWTAGASFGSTVPGTGIGATAIGPGRLRIYYQATDNKIREHCWDSNSWYVGGFSASASAGVSIAAISWGSTPQIRVYWQKGREELYEAAYGGSWNTPGQIKDASRPTPSLPDTFIAANSSGNIDISVFFQASGVSLQQWQWISGKGWSIGAVVPTGTPAGWL 5npo B 1.95 BS01 MG B 1 I285 K286 I219 K220 3.5.2.6 D3INY1 29211984 KRVGYIELDLASGKILVSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEERDTTTPVAMATTLRKLLTGELLTAASRQQLIDWMEALPAGWFIADKSRGIIAALGPDGKPSRIVVIYMTGATMDERNRQIAEIGASLIKHWA 5nqa A 1.90 BS01 NGA A 1 D459 N461 F475 H478 Q480 G481 N483 Q484 D395 N397 F411 H414 Q416 G417 N419 Q420 2.4.1.41 Q8N4A0 29208955 DLSRPLYKKPPADSRALGEWGKASKLQLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVYLKTQLETYISNLDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDWRLTFQWHSVPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKNFLQNTARAAEVWMDEYKEHFYNRNPPARKEAYGDISERKLLRERLRCKSFDWYLKNVFPNLHVPEDRPGWHGAIRSRGISSECLDYNSPDNNPTGANLSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPEQKNYVGMQNCPKDGFPVPANIIWHFKEDGTIFHPHSGLCLSAYRTPEGRPDVQMRTCDALDKNQIWSFEK 5nqa B 1.90 BS01 NGA G 1 D459 N461 F475 H478 Q480 N483 Q484 D395 N397 F411 H414 Q416 N419 Q420 2.4.1.41 Q8N4A0 29208955 LSRPLYKKPPADSRALGEWGKASKLQLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVYLKTQLETYISNLDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDWRLTFQWHSVPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRNFLQNTARAAEVWMDEYKEHFYNRNPPARKEAYGDISERKLLRERLRCKSFDWYLKNVFPNLHVPEDRPGWHGAIRSRGISSECLDYNSPDNNPTGANLSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPEQKNYVGMQNCPKDGFPVPANIIWHFKEDGTIFHPHSGLCLSAYRTPEGRPDVQMRTCDALDKNQIWSFEK 5ns3 A 2.40 BS01 NUC C 1 K36 V38 N40 R91 S124 F125 D126 R128 N130 N132 G134 D156 A158 K32 V34 N36 R66 S96 F97 D98 R100 N102 N104 G106 D110 A112 P41201 29211987 VALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLILEKAAQELALITGQKPAVTRAPIGLRVTLRRDRMWIFLEKLLNVALPRIRGLNPNSFDGRGNYNLGLGMDIAVVTTAETDEEARALLELLGFPFR 5ns3 A 2.40 BS02 NUC D 1 Q66 K67 A69 R91 V92 T93 R95 R96 R98 Q54 K55 A57 R66 V67 T68 R70 R71 R73 P41201 29211987 VALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLILEKAAQELALITGQKPAVTRAPIGLRVTLRRDRMWIFLEKLLNVALPRIRGLNPNSFDGRGNYNLGLGMDIAVVTTAETDEEARALLELLGFPFR 5ns3 B 2.40 BS02 NUC D 1 K36 V38 N40 T71 I88 R91 S124 F125 D126 R128 N130 N132 L133 G134 D156 A158 V160 K32 V34 N36 T56 I64 R67 S99 F100 D101 R103 N105 N107 L108 G109 D113 A115 V117 P41201 29211987 VALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINILEKAAQELALITGQKPAVTRAKKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRFRGLNPNSFDGRGNYNLGLGMDIAVVTTAETDEEARALLELLGFPFR 5ns4 A 2.40 BS02 MG A 1 R128 G129 N130 T161 A163 R100 G101 N102 T118 A120 P41201 29211987 DVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLILEKAAQELALITGQKPAVTRAGMPIGLRVTLRRDRMWIFLEKLLNVALPGLNPNSFDGRGNYNLGLREQGMDIAVVTTAETDEEARALLELLGFPFR 5o6e A 3.35 BS01 NUC C 1 T290 G291 T301 H303 S304 G309 L310 K312 V385 K387 S463 T464 R465 K525 N526 N533 A679 S703 H705 K706 R721 F723 T55 G56 T66 H68 S69 G74 L75 K77 V150 K152 S228 T229 R230 K290 N291 N298 A428 S452 H454 K455 R470 F472 3.6.4.12 P07271 29202194 GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLT 5o6e A 3.35 BS02 ADP A 1 G236 L237 Q241 G261 T262 G263 K264 S265 I266 F416 R417 R419 T711 G1 L2 Q6 G26 T27 G28 K29 S30 I31 F181 R182 R184 T460 3.6.4.12 P07271 29202194 GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLT 5o6e A 3.35 BS03 ALF A 1 A260 G261 K264 S265 E342 Q381 R417 G709 R734 A25 G26 K29 S30 E107 Q146 R182 G458 R483 3.6.4.12 P07271 29202194 GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLT 5o6e A 3.35 BS04 MG A 1 S265 D341 E342 S30 D106 E107 3.6.4.12 P07271 29202194 GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLT 5o6e B 3.35 BS01 NUC D 1 T290 G291 T301 S304 L310 K312 V385 K387 T464 R465 N506 F507 K525 S703 H705 K706 F723 T55 G56 T66 S69 L75 K77 V150 K152 T229 R230 N271 F272 K290 S452 H454 K455 F472 3.6.4.12 P07271 29202194 GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTL 5o6e B 3.35 BS02 ADP B 1 G236 L237 S238 Q241 A260 G261 T262 G263 K264 S265 I266 F416 R417 R419 T711 G1 L2 S3 Q6 A25 G26 T27 G28 K29 S30 I31 F181 R182 R184 T460 3.6.4.12 P07271 29202194 GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTL 5okc A 2.30 BS01 III I 1 P13 K16 F39 S41 K44 D45 S47 E48 V49 L60 K61 Q62 R63 K64 H65 S66 N67 F108 E109 P12 K15 F38 S40 K43 D44 S46 E47 V48 L59 K60 Q61 R62 K63 H64 S65 N66 F107 E108 P25559 29225079 SINLHSAPEYDPSYKLIQLTPELLDIIQDPVQNHQLRFKSLDKDKSEVVLCSHDKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGFAKTESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENSPCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQHLNVEDTHHAVGKDIEDEFNPYTREIIETVLNKFAVQEQNTWRLRIPFIAQWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEELNSRGMKIDSFIMKYARRKTVVTS 5okc B 2.30 BS01 III G 1 K16 F39 S41 D43 K44 D45 S47 E48 V49 L60 K61 Q62 R63 K64 H65 S66 N67 F108 E109 R111 K15 F38 S40 D42 K43 D44 S46 E47 V48 L59 K60 Q61 R62 K63 H64 S65 N66 F107 E108 R110 P25559 29225079 SINLHSAPEYDPSYKLIQLTPELLDIIQDPVQNHQLRFKSLDKDKSEVVLCSHDKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGFAKTESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENSPCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQHLNVEDTHHAVGKDIEDEFNPYTREIIETVLNKFAVQEQENNTWRLRIPFIAQWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEELNSRGMKIDSFIMKYARRKRLGKKTVVTSR 5okc F 2.30 BS01 III G 1 P2 S3 V4 I35 Q36 G37 E38 E40 R58 I68 F70 V84 G85 Q88 F106 N107 S108 N111 K126 D127 R128 P129 P1 S2 V3 I34 Q35 G36 E37 E39 R57 I67 F69 V83 G84 Q87 F105 N106 S107 N110 K125 D126 R127 P128 P38877 29225079 PSVDIDASQWQKLTQSREKQTTVITPLGMMMLEIQGELELPKDFASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKKQRLLGKVTKLDVPMGIMHFNSKDNKVELVDVMKYKVIFKDRPLPIM 5okc H 2.30 BS01 III I 1 P2 S3 V4 Q36 G37 E38 E40 L48 R51 R58 F59 I68 F70 V84 G85 Q88 F106 N107 S108 N111 V113 K126 D127 R128 P129 P1 S2 V3 Q31 G32 E33 E35 L43 R46 R53 F54 I63 F65 V79 G80 Q83 F101 N102 S103 N106 V108 K121 D122 R123 P124 P38877 29225079 PSVDIDASQWQKLTQSRTVITPLGMMMLEIQGELELPKDFASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKKQRLLGKVTKLDVPMGIMHFNSKDNKVELVDVMKYKVIFKDRPLPIM 5oki C 4.50 BS01 III E 1 K44 D45 E48 V49 L60 K61 Q62 R63 K64 S66 N67 K43 D44 E47 V48 L59 K60 Q61 R62 K63 S65 N66 P25559 29225079 SINLHSAPEYDPSYKLIQLTPELLDIIQDPVQNHQLRFKSLDKDKSEVVLCSHDKTWVLKQRKHSNTVLLMREFVPEQPITTLLFSKPYMDVVGFAKTESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENSPCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQHLNVEDTHHAVGKDIEDEFNPYTREIIETVLNKFAVQENNTWRLRIPFIAQWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGYHFKKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEELNSRGMKIDSFIMKYARRKRLGKKTVVTSR 5oki D 4.50 BS01 III E 1 P2 V4 I35 Q36 G37 E38 L39 E40 P42 F70 K87 Q88 F106 S108 N111 K126 D127 R128 P1 V3 I34 Q35 G36 E37 L38 E39 P41 F69 K86 Q87 F105 S107 N110 K125 D126 R127 P38877 29225079 PSVDIDASQWQKLTQSREKQTTVITPLGMMMLEIQGELELPKDFASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKKQRLLGKVTKLDVPMGIMHFNSKDNKVELVDVMKYKVIFKDRPLPI 5oki G 4.50 BS01 III I 1 K16 D43 K44 D45 E48 V49 L60 K61 Q62 R63 K64 H65 S66 N67 K15 D42 K43 D44 E47 V48 L59 K60 Q61 R62 K63 H64 S65 N66 P25559 29225079 SINLHSAPEYDPSYKLIQLTPELLDIIQDPVQNHQLRFKSLDKDKSEVVLCSHDKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGFAKTESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENSPCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQHLNVEDTHHAVGKDIEDEFNPYTREIIETVLNKFAVQEQENTWRLRIPFIAQWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGYHFKKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEELNSRGMKIDSFIMKYARRKRLGKKTVVTSR 5oki H 4.50 BS01 III I 1 P2 I35 Q36 G37 E38 L39 E40 L41 I68 F70 V84 K87 Q88 S108 N111 R128 P129 P1 I34 Q35 G36 E37 L38 E39 L40 I67 F69 V83 K86 Q87 S107 N110 R127 P128 P38877 29225079 PSVDIDASQWQKLTQSREKQTTVITPLGMMMLEIQGELELPKDFASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKKQRLLGKVTKLDVPMGIMHFNSKDNKVELVDVMKYKVIFKDRPLPI 5omf A 2.09 BS01 NUC T 1 S348 T349 G350 S383 Y384 E385 G386 G387 V389 S492 Y494 G495 Y496 G498 Y499 R501 T590 K591 K592 K593 W615 T676 P678 R709 I710 G711 Y731 N735 P739 R743 S348 T349 G350 S383 Y384 E385 G386 G387 V389 S492 Y494 G495 Y496 G498 Y499 R501 T590 K591 K592 K593 W615 T676 P678 R709 I710 G711 Y731 N735 P739 R743 2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.- P77933 29211756 MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEEVKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKIREHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGEEFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKEKDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWETGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIPSLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSYYGYYGYARARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPGADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGYRKEDLR 5omf A 2.09 BS02 NUC P 1 D540 T541 K592 Y594 R606 G607 V611 R612 R613 D614 Q665 T667 R668 Y673 K674 A675 H679 D540 T541 K592 Y594 R606 G607 V611 R612 R613 D614 Q665 T667 R668 Y673 K674 A675 H679 2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.- P77933 29211756 MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEEVKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKIREHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGEEFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKEKDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWETGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIPSLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSYYGYYGYARARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPGADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGYRKEDLR 5omf A 2.09 BS03 MN A 1 D404 F405 E580 D404 F405 E580 2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.- P77933 29211756 MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEEVKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKIREHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGEEFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKEKDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWETGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIPSLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSYYGYYGYARARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPGADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGYRKEDLR 5omf A 2.09 BS04 MN A 2 D404 F405 D542 D404 F405 D542 2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.- P77933 29211756 MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEEVKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKIREHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGEEFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKEKDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWETGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIPSLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSYYGYYGYARARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPGADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGYRKEDLR 5omf A 2.09 BS05 MG A 1 Y402 D404 D542 Y402 D404 D542 2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.- P77933 29211756 MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEEVKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKIREHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGEEFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKEKDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWETGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIPSLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSYYGYYGYARARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPGADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGYRKEDLR 5omf A 2.09 BS06 DTP A 1 D404 F405 R406 S407 L408 Y409 P410 R460 K487 I488 N491 D542 D404 F405 R406 S407 L408 Y409 P410 R460 K487 I488 N491 D542 2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.-,2.7.7.7,3.1.-.- P77933 29211756 MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYFYALLKDDSAIEEVKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIRDKIREHPAVIDIYEYDIPFAKRYLIDKGLVPMEGDEELKMLAFAIATLYHEGEEFAEGPILMISYADEEGARVITWKNVDLPYVDVVSTEREMIKRFLRVVKEKDPDVLITYNGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWETGENLERVARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYERNELAPNKPDEKELARRRQSYEGGYVKEPERGLWENIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIPSLLGDLLEERQKIKKKMKATIDPIERKLLDYRQRAIKILANSYYGYYGYARARWYCKECAESVTAWGREYITMTIKEIEEKYGFKVIYSDTDGFFATIPGADAETVKKKAMEFLKYINAKLPGALELEYEGFYKRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPFDEFDPTKHKYDAEYYIENQVLPAVERILRAFGYRKEDLR 5omq A 2.20 BS01 NUC T 1 S348 T349 G350 Y384 A385 G386 G387 V389 I488 S492 G495 G498 Y499 K501 T590 K591 K592 K593 W615 P678 R709 I710 G711 Y731 N735 P739 R743 S348 T349 G350 Y384 A385 G386 G387 V389 I488 S492 G495 G498 Y499 K501 T590 K591 K592 K593 W615 P678 R709 I710 G711 Y731 N735 P739 R743 2.7.7.7 Q56366 29211756 MILDTDYITENGKPVIRVFKKENGEFKIEYDRTFEPYFYALLKDDSAIEDVKKVTAKRHGTVVKVKRAEKVQKKFLGRPIEVWKLYFNHPQDVPAIRDRIRAHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELTMLAFAIATLYHEGEEFGTGPILMISYADGSEARVITWKKIDLPYVDVVSTEKEMIKRFLRVVREKDPDVLITYNGDNFDFAYLKKRCEELGIKFTLGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGKPKEKVYAEEIAQAWESGEGLERVARYSMEDAKVTYELGREFFPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYKRNELAPNKPDERELARRRGGYAGGYVKEPERGLWDNIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPEVGHKFCKDFPGFIPSLLGDLLEERQKIKRKMKATVDPLEKKLLDYRQRAIKILANSFYGYYGYAKARWYCKECAESVTAWGREYIEMVIRELEEKFGFKVLYADTDGLHATIPGADAETVKKKAKEFLKYINPKLPGLLELEYEGFYVRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEAILKHGDVEEAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLRDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPADEFDPTKHRYDAEYYIENQVLPAVERILKAFGYRKEDLRYQ 5omq A 2.20 BS03 MG A 1 D404 D542 D404 D542 2.7.7.7 Q56366 29211756 MILDTDYITENGKPVIRVFKKENGEFKIEYDRTFEPYFYALLKDDSAIEDVKKVTAKRHGTVVKVKRAEKVQKKFLGRPIEVWKLYFNHPQDVPAIRDRIRAHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELTMLAFAIATLYHEGEEFGTGPILMISYADGSEARVITWKKIDLPYVDVVSTEKEMIKRFLRVVREKDPDVLITYNGDNFDFAYLKKRCEELGIKFTLGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGKPKEKVYAEEIAQAWESGEGLERVARYSMEDAKVTYELGREFFPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYKRNELAPNKPDERELARRRGGYAGGYVKEPERGLWDNIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPEVGHKFCKDFPGFIPSLLGDLLEERQKIKRKMKATVDPLEKKLLDYRQRAIKILANSFYGYYGYAKARWYCKECAESVTAWGREYIEMVIRELEEKFGFKVLYADTDGLHATIPGADAETVKKKAKEFLKYINPKLPGLLELEYEGFYVRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEAILKHGDVEEAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLRDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPADEFDPTKHRYDAEYYIENQVLPAVERILKAFGYRKEDLRYQ 5omq A 2.20 BS04 MG A 2 D404 E580 D404 E580 2.7.7.7 Q56366 29211756 MILDTDYITENGKPVIRVFKKENGEFKIEYDRTFEPYFYALLKDDSAIEDVKKVTAKRHGTVVKVKRAEKVQKKFLGRPIEVWKLYFNHPQDVPAIRDRIRAHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELTMLAFAIATLYHEGEEFGTGPILMISYADGSEARVITWKKIDLPYVDVVSTEKEMIKRFLRVVREKDPDVLITYNGDNFDFAYLKKRCEELGIKFTLGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGKPKEKVYAEEIAQAWESGEGLERVARYSMEDAKVTYELGREFFPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYKRNELAPNKPDERELARRRGGYAGGYVKEPERGLWDNIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPEVGHKFCKDFPGFIPSLLGDLLEERQKIKRKMKATVDPLEKKLLDYRQRAIKILANSFYGYYGYAKARWYCKECAESVTAWGREYIEMVIRELEEKFGFKVLYADTDGLHATIPGADAETVKKKAKEFLKYINPKLPGLLELEYEGFYVRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEAILKHGDVEEAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLRDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPADEFDPTKHRYDAEYYIENQVLPAVERILKAFGYRKEDLRYQ 5omv A 2.00 BS02 NUC P 1 N269 D540 T541 K592 Y594 R606 G607 V611 R612 R613 D614 E664 Q665 T667 R668 Y673 K674 A675 H679 N269 D540 T541 K592 Y594 R606 G607 V611 R612 R613 D614 E664 Q665 T667 R668 Y673 K674 A675 H679 2.7.7.7 Q56366 29211756 MILDTDYITENGKPVIRVFKKENGEFKIEYDRTFEPYFYALLKDDSAIEDVKKVTAKRHGTVVKVKRAEKVQKKFLGRPIEVWKLYFNHPQDVPAIRDRIRAHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELTMLAFAIATLYHEGEEFGTGPILMISYADGSEARVITWKKIDLPYVDVVSTEKEMIKRFLRVVREKDPDVLITYNGDNFDFAYLKKRCEELGIKFTLGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGKPKEKVYAEEIAQAWESGEGLERVARYSMEDAKVTYELGREFFPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYKRNELAPNKPDERELARRRGGYAGGYVKEPERGLWDNIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPEVGHKFCKDFPGFIPSLLGDLLEERQKIKRKMKATVDPLEKKLLDYRQRAIKILANSFYGYYGYAKARWYCKECAESVTAWGREYIEMVIRELEEKFGFKVLYADTDGLHATIPGADAETVKKKAKEFLKYINPKLPGLLELEYEGFYVRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEAILKHGDVEEAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLRDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPADEFDPTKHRYDAEYYIENQVLPAVERILKAFGYRKEDLRYQ 5org A 1.99 BS01 6DB A 1 E30 Y33 W71 A88 A89 M90 S91 R96 G109 N111 Q159 T162 T163 N202 F230 V233 E11 Y14 W52 A69 A70 M71 S72 R77 G90 N92 Q140 T143 T144 N183 F211 V214 P0A4F8 MQEKSITIATEGGYAPWNFSGPGGKLDGFEIDLANALCEKMKAKCQIVAQNWDGIMPSLTGKKYDAIMAAMSVTPKRQEVIGFSIPYAAGINGFAVMGDSKLAEMPGLGETYSLDSQADAAKKAIADISSFLNGTTVGVQGSTTASTFLDKYFKGSVDIKEYKSVEEHNLDLTSGRLDAVLANATVLAAAIEKPEMKGAKLVGPLFSGGEFGVVAVGLRKEDTALKADFDAAIKAASEDGTIKTLSLKWFKVDVTPQ 5osk B 2.11 BS02 A9Q B 1 V238 C241 L242 L248 A250 L255 N258 M259 T314 V315 A317 I318 N349 N350 K352 A354 V236 C239 L240 L246 A247 L252 N255 M256 T306 V307 A309 I310 N341 N342 K344 A346 Q6B856 29227648 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLADLRKLAVNMVPFPRLHFFMPGFAPLTQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 5osk D 2.11 BS01 GDP D 1 Q11 C12 Q15 S140 G143 G144 T145 G146 E183 N206 Y224 N228 Q10 C11 Q14 S137 G140 G141 T142 G143 E180 N203 Y221 N225 Q6B856 29227648 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5osk F 2.11 BS01 MG F 1 E331 N333 E276 N278 E1BQ43 29227648 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGGNVWIAKSSEASEHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSADKTCHLTNHCIQKYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH 5osk F 2.11 BS02 ACP F 1 K74 I148 K150 Q183 K184 Y185 L186 K198 R222 L240 T241 D318 M320 I330 E331 N333 K74 I124 K126 Q136 K137 Y138 L139 K151 R175 L190 T191 D263 M265 I275 E276 N278 E1BQ43 29227648 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGGNVWIAKSSEASEHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSADKTCHLTNHCIQKYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH 5ot8 A 2.35 BS01 6DB A 1 E36 Y39 W77 A94 A95 S97 R102 M117 Q165 T168 S169 H170 S207 V239 E10 Y13 W51 A68 A69 S71 R76 M91 Q139 T142 S143 H144 S181 V213 P35120 DYKSITIATEGSYAPYNFKDAGGKLIGFDIDLGNDLCKRMNIECKFVEQAWDGIIPSLTAGRYDAIMAAMSIQPAREKVIAFSRPYLLTPMTFLTTADSPLLKTQVAIENLPLDNITPEQKAELDKFTKIFEGVKFGVQAGTSHEAFMKQMMPSVQISTYDTIDNVVMDLKAGRIDASLASVSFLKPLTDKPDNKDLKMFGPRMTGGLFGKGVGVGIRKEDADLKALFDKAIDAAIADGTVQKLSQQWFGYDASPK 5ot9 B 2.45 BS01 AOZ B 1 E36 Y39 W77 A94 A95 G97 R102 M117 Q165 T168 S169 H170 S207 E8 Y11 W49 A66 A67 G69 R74 M89 Q137 T140 S141 H142 S179 P35120 KSITIATEGSYAPYNFKDAGGKLIGFDIDLGNDLCKRMNIECKFVEQAWDGIIPSLTAGRYDAIMAAMGIQPAREKVIAFSRPYLLTPMTFLTTADSPLLKTQVAIENLPLDNITPEQKAELDKFTKIFEGVKFGVQAGTSHEAFMKQMMPSVQISTYDTIDNVVMDLKAGRIDASLASVSFLKPLTDKPDNKDLKMFGPRMTGGLFGKGVGVGIRKEDADLKALFDKAIDAAIADGTVQKLSQQWFGYDASP 5ota A 2.10 BS01 AQQ A 1 E36 Y39 W77 A95 G97 R102 M117 Q165 T168 S169 H170 S207 F210 V239 E9 Y12 W50 A68 G70 R75 M90 Q138 T141 S142 H143 S180 F183 V212 P35120 YKSITIATEGSYAPYNFKDAGGKLIGFDIDLGNDLCKRMNIECKFVEQAWDGIIPSLTAGRYDAIMAAMGIQPAREKVIAFSRPYLLTPMTFLTTADSPLLKTQVAIENLPLDNITPEQKAELDKFTKIFEGVKFGVQAGTSHEAFMKQMMPSVQISTYDTIDNVVMDLKAGRIDASLASVSFLKPLTDKPDNKDLKMFGPRMTGGLFGKGVGVGIRKEDADLKALFDKAIDAAIADGTVQKLSQQWFGYDASP 5oug A 2.57 BS01 L0B A 1 L36 W53 L104 L106 Q114 L116 L37 W54 L105 L107 Q115 L117 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug A 2.57 BS02 9Z0 A 1 L54 I88 R96 I119 F142 L55 I89 R97 I120 F143 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug A 2.57 BS03 9Z0 A 2 L6 Y7 E9 L10 L63 Q64 Y70 V76 V78 V107 L7 Y8 E10 L11 L64 Q65 Y71 V77 V79 V108 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug B 2.57 BS03 9Z0 B 1 L54 I88 L89 L90 R96 P97 I119 Q121 F142 L55 I89 L90 L91 R97 P98 I120 Q122 F143 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug C 2.57 BS03 9Z0 C 1 L54 I88 L89 L90 P97 I119 Q121 F142 L55 I89 L90 L91 P98 I120 Q122 F143 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug C 2.57 BS04 9Z0 C 2 L6 Y7 E9 L10 Y62 L63 Q64 W65 V76 V107 L7 Y8 E10 L11 Y63 L64 Q65 W66 V77 V108 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug C 2.57 BS05 L0B C 1 W145 T146 C186 W146 T147 C187 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug D 2.57 BS03 9Z0 D 1 L54 I88 L89 L90 R96 P97 I119 Q121 L55 I89 L90 L91 R97 P98 I120 Q122 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug D 2.57 BS04 9Z0 D 2 L6 Y7 E9 L10 Y62 L63 Q64 V76 V107 L7 Y8 E10 L11 Y63 L64 Q65 V77 V108 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug E 2.57 BS04 9Z0 E 1 L54 I88 L90 R96 P97 I119 Q121 F142 L55 I89 L91 R97 P98 I120 Q122 F143 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oug E 2.57 BS05 9Z0 E 2 L6 Y7 E9 L10 L63 Q64 W65 Y70 V76 V107 L7 Y8 E10 L11 L64 Q65 W66 Y71 V77 V108 GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEVLTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHSRELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVTFRKKG 5oyb A 3.75 BS01 CA A 1 E654 E702 E705 E734 D738 E476 E510 E513 E542 D546 Q8BHY3 2017 MDYHEDDKRFRREELCREAEFLKLKMPTKKVYHISETRGLLKTINSVLQKITDPIQPKVAEHRPQTTKRLSYPFSREKQHLFDLTDRDSFFDSKTRSTIVYEILKRTTCGITSLLANGVYSAAYPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKRKQRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMR 5oyb A 3.75 BS02 CA A 2 N650 N651 E654 E705 E734 N472 N473 E476 E513 E542 Q8BHY3 2017 MDYHEDDKRFRREELCREAEFLKLKMPTKKVYHISETRGLLKTINSVLQKITDPIQPKVAEHRPQTTKRLSYPFSREKQHLFDLTDRDSFFDSKTRSTIVYEILKRTTCGITSLLANGVYSAAYPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKRKQRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMR 5qbu A 2.78 BS01 B8J A 1 W26 K60 G62 G69 F70 M71 T73 Y118 G137 Q160 N161 V162 N163 H164 G165 F211 W26 K60 G62 G69 F70 M71 T73 Y118 G137 Q160 N161 V162 N163 H164 G165 F211 3.4.22.27 P25774 LPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQ 5qbw A 3.01 BS01 B8S A 1 G62 K64 N67 G68 G69 F70 M71 T73 G137 V162 N163 H164 G165 F211 G62 K64 N67 G68 G69 F70 M71 T73 G137 V162 N163 H164 G165 F211 3.4.22.27 P25774 LPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEIL 5qbx B 2.10 BS01 B8V B 1 K60 G62 G69 F70 M71 T73 G137 V162 N163 H164 G165 F211 K61 G63 G70 F71 M72 T74 G138 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEIL 5qc0 A 1.90 BS01 BQJ A 1 W26 G62 G69 F70 M71 T72 E115 G137 V162 N163 H164 G165 F211 W27 G63 G70 F71 M72 T73 E116 G138 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQ 5qc1 A 2.08 BS01 B9S A 1 W26 G62 K64 N67 G68 G69 F70 M71 G137 N161 V162 N163 H164 G165 F211 W27 G63 K65 N68 G69 G70 F71 M72 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQG 5qc2 A 2.26 BS01 BQP A 1 W26 K60 Y61 G62 K64 G68 G69 F70 M71 T72 E115 G137 V162 N163 H164 G165 F211 W26 K60 Y61 G62 K64 G68 G69 F70 M71 T72 E115 G137 V162 N163 H164 G165 F211 3.4.22.27 P25774 LPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQ 5qc3 A 2.00 BS01 B9Y A 1 W26 G62 K64 G68 G69 F70 M71 Y118 G137 N161 V162 N163 H164 G165 F211 W27 G63 K65 G69 G70 F71 M72 Y119 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQG 5qc3 B 2.00 BS01 B9Y B 1 W26 K64 G69 F70 M71 T73 Y118 G137 N161 V162 N163 H164 G165 F211 W27 K65 G70 F71 M72 T74 Y119 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQG 5qc4 A 2.00 BS01 BC7 A 1 K64 N67 G68 G69 F70 M71 G137 N161 V162 N163 H164 G165 F211 K65 N68 G69 G70 F71 M72 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 20188543 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQG 5qc7 A 1.90 BS01 BQS A 1 K60 Y61 G62 K64 G69 F70 M71 T72 T73 E115 G137 V162 N163 H164 G165 F211 K61 Y62 G63 K65 G70 F71 M72 T73 T74 E116 G138 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQ 5qc7 B 1.90 BS01 BQS B 1 Y61 G62 K64 G69 F70 M71 T72 E115 G137 V162 N163 H164 G165 F211 Y62 G63 K65 G70 F71 M72 T73 E116 G138 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQG 5qc8 B 1.74 BS01 BFV B 1 G23 G62 K64 N67 G68 G69 F70 M71 T73 G137 N161 V162 N163 H164 G165 F211 G24 G63 K65 N68 G69 G70 F71 M72 T74 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQG 5qca A 2.29 BS01 BGJ A 1 S21 C22 G23 Y61 G62 C66 N67 G68 G69 F70 M71 T73 G137 N161 V162 N163 H164 G165 F211 S22 C23 G24 Y62 G63 C67 N68 G69 G70 F71 M72 T74 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEIL 5qca B 2.29 BS01 BGJ B 1 G69 F70 M71 G137 N161 V162 N163 H164 G165 F211 G70 F71 M72 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 5qcc A 1.80 BS01 BGY A 1 F70 M71 V162 N163 H164 G165 F211 F71 M72 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQG 5qcd A 1.95 BS01 BHJ A 1 G23 N67 G68 G69 F70 M71 T73 G137 N161 V162 N163 H164 G165 F211 G24 N68 G69 G70 F71 M72 T74 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQGGG 5qce A 2.78 BS01 BJD A 1 G23 S25 G62 K64 N67 G68 G69 F70 M71 T73 G137 N161 V162 N163 H164 G165 F211 G24 S26 G63 K65 N68 G69 G70 F71 M72 T74 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQ 5qce B 2.78 BS01 BJD B 1 G23 S25 N67 G68 F70 M71 T73 G137 N161 V162 N163 H164 G165 F211 G23 S25 N67 G68 F70 M71 T73 G137 N161 V162 N163 H164 G165 F211 3.4.22.27 P25774 LPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQGG 5qcf A 2.10 BS01 BJD A 1 F70 M71 T73 A140 R141 F146 N161 V162 N163 H164 G165 W186 F211 F70 M71 T73 A140 R141 F146 N161 V162 N163 H164 G165 W186 F211 3.4.22.27 P25774 LPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQG 5qcg A 2.70 BS01 BJJ A 1 F70 M71 T73 A140 R141 N161 V162 N163 H164 G165 F211 F70 M71 T73 A140 R141 N161 V162 N163 H164 G165 F211 3.4.22.27 P25774 LPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQ 5qcg B 2.70 BS01 BJJ B 1 F70 M71 A140 N161 V162 N163 H164 G165 F211 F71 M72 A141 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQGGG 5qch A 2.20 BS01 BJS A 1 F70 T73 A140 R141 F146 N161 V162 N163 H164 G165 F211 F71 T74 A141 R142 F147 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQGGG 5qcj A 2.00 BS01 BJY A 1 K60 Y61 G62 G69 F70 M71 T73 G137 N161 V162 N163 H164 G165 F211 K61 Y62 G63 G70 F71 M72 T74 G138 N162 V163 N164 H165 G166 F212 3.4.22.27 P25774 ILPDSVDWREKGCVTEVKYQGSCGASWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEILQG 5u93 A 2.00 BS01 RM4 A 1 L7 R25 Q28 F31 H34 H36 E40 H74 Y76 N86 L2 R20 Q23 F26 H29 H31 E35 H69 Y71 N81 C5A074 KLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFNASAGQPHWRLGSMGMAQARQVIGQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYT 5u93 B 2.00 BS01 RM4 B 1 L7 F12 R25 Q28 F31 H34 H36 E40 H74 Y76 N86 L3 F8 R21 Q24 F27 H30 H32 E36 H70 Y72 N82 C5A074 LKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFNASAGQPHWRLGSMGMAQARQVIGQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYT 5u94 A 2.20 BS01 G93 A 1 L17 G18 F19 V25 A38 K40 E59 A63 V72 V74 M92 E93 Y94 V95 A142 M145 M155 D156 F157 L15 G16 F17 V23 A36 K38 E57 A61 V70 V72 M90 E91 Y92 V93 A140 M143 M153 D154 F155 2.7.11.1 P9WI81 TPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIARAIIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHN 5u9e A 2.02 BS01 RM4 A 1 L7 F12 A23 F31 H34 H36 F38 E40 H74 Y76 N86 I88 L5 F10 A21 F24 H27 H29 F31 E33 H67 Y69 N79 I81 C5A074 HQLKLLKDDFFASDQQAVAVADVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFNASAGQPHWRLGSMGMAQARQVIGQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYT 5u9l A 2.52 BS01 MG A 1 W700 E701 K704 Y794 Y798 W34 E35 K38 Y128 Y132 Q8VY16 GIVGNIKVLIDMLKMHCHKRPMDTEEAEELVRQWENVKAEALGPTHQVYSLSEVLDESMLVQWQTLAQTAEAKSCYWRFVLLHLEVLQAHIFEDGIAGEAAEIEALLEEAAELVDESQPKNAKYYSTYKIRYILKKQEDGLWKFCQSDIQIQ 5u9l B 2.52 BS01 MG B 1 W700 Y798 W34 Y132 Q8VY16 IVGNIKVLIDMLKMHCLHKRPMDTEEAEELVRQWENVKAEALGPTHQVYSLSEVLDESMLVQWQTLAQTAEAKSCYWRFVLLHLEVLQAHIFEDGIAGEAAEIEALLEEAAELVDESQPKNAKYYSTYKIRYILKKQEDGLWKFCQSDIQI 5u9z A 2.00 BS01 MN A 1 E488 T530 D711 H712 E46 T88 D269 H270 A0A127X8Q2 GMEKPTNYSQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPNIKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHTISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTSDKTVYNNILSLINPSESQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARLLSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNGTNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQNDLKNIQYDVTIGKGYLLKHKTFFKI 5ua2 A 2.90 BS01 NUC M 1 R38 R61 D68 V69 A70 T73 Y77 R8 R31 D38 V39 A40 T43 Y47 P96856 GSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIG 5ub9 A 1.90 BS01 ZN A 1 H33 H35 H29 H31 2.4.2.17 Q5HSJ4 29208762 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARE 5ubg A 1.90 BS02 PRT A 1 Q12 G15 R16 R54 D55 D56 N75 V76 G102 Y103 C104 L170 S172 S173 G174 A175 T176 Q9 G12 R13 R51 D52 D53 N72 V73 G99 Y100 C101 L167 S169 S170 G171 A172 T173 2.4.2.17 Q5HSJ4 29208762 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARE 5ubg A 1.90 BS03 ZN A 2 D55 D56 D52 D53 2.4.2.17 Q5HSJ4 29208762 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARE 5ubg B 1.90 BS02 PRT B 1 Q12 G15 R16 R54 D55 D56 G73 N75 V76 G102 Y103 C104 L170 V171 S172 S173 G174 A175 T176 Q9 G12 R13 R51 D52 D53 G70 N72 V73 G99 Y100 C101 L167 V168 S169 S170 G171 A172 T173 2.4.2.17 Q5HSJ4 29208762 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARE 5ubh A 2.00 BS03 ATP A 1 Q12 G15 R16 L17 R54 D55 D56 G73 N75 V76 Y103 C104 L170 S172 Q9 G12 R13 L14 R51 D52 D53 G70 N72 V73 Y100 C101 L167 S169 2.4.2.17 Q5HSJ4 29208762 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGV 5ubh B 2.00 BS02 ATP B 1 Q12 G15 R16 R54 D55 D56 G73 N75 V76 C104 Y131 L170 S172 Q9 G12 R13 R51 D52 D53 G70 N72 V73 C101 Y128 L167 S169 2.4.2.17 Q5HSJ4 29208762 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARE 5ubi A 2.14 BS04 PRP A 1 Q12 D55 D169 L170 V171 S172 S173 G174 A175 T176 Q9 D52 D166 L167 V168 S169 S170 G171 A172 T173 2.4.2.17 Q5HSJ4 29208762 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVM 5ubi B 2.14 BS02 ZN B 2 D100 E225 D97 E222 2.4.2.17 Q5HSJ4 29208762 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARE 5ubi B 2.14 BS03 PRP B 1 R16 D55 E156 D169 L170 S172 S173 G174 T176 R13 D52 E153 D166 L167 S169 S170 G171 T173 2.4.2.17 Q5HSJ4 29208762 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARE 5ubi B 2.14 BS04 MG B 1 Q12 G15 R16 Q9 G12 R13 2.4.2.17 Q5HSJ4 29208762 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARE 5ujt A 1.94 BS01 III C 1 Y9 Y22 H24 W43 R52 R53 F54 F58 N62 V65 L66 H68 N69 C72 V73 K75 R76 Y10 Y24 H26 W45 R54 R55 F56 F60 N64 V67 L68 H70 N71 C74 V75 K77 R78 Q5Y7C3 DIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNCVIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSDDEIYDCKVEHWGLDEPLLKHWEPE 5ujt B 1.94 BS01 III C 1 F11 G13 L26 Y30 Y37 A57 Y60 W61 R70 E74 T77 V78 H81 N82 L85 F9 G11 L24 Y28 Y35 A55 Y58 W59 R68 E72 T75 V76 H79 N80 L83 O19707 SPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTISPSTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQ 5ujt D 1.94 BS01 III F 1 Y9 Y22 H24 W43 R52 R53 F54 F58 N62 V65 H68 N69 C72 V73 R76 Y11 Y25 H27 W46 R55 R56 F57 F61 N65 V68 H71 N72 C75 V76 R79 Q5Y7C3 EDIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNCVIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSDDEIYDCKVEHWGLDEPLLKHW 5v3q A 2.25 BS01 MLX A 1 M29 C32 P33 F34 L56 K57 V127 W222 Y229 M27 C30 P31 F32 L54 K55 V125 W220 Y227 2.5.1.18,1.8.5.1,1.20.4.2 P78417 GESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL 5vfm A 2.06 BS01 HC4 A 1 K16 K20 K115 R118 Y119 K15 K19 K105 R108 Y109 Q9IAT9 28751219 SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGQPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKADPC 5vs6 A 2.27 BS01 9QD A 1 Y224 D295 V296 Q297 L406 M407 R408 F409 K420 H456 N460 H461 Y465 Y514 Y17 D88 V89 Q90 L199 M200 R201 F202 K213 H249 N253 H254 Y258 Y299 3.4.19.12 Q93009 29056421 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQK 5vsb B 1.85 BS01 9QA B 1 Y224 M292 D295 V296 Q297 Q405 M407 F409 M410 K420 H456 Y465 Y514 Y17 M85 D88 V89 Q90 Q198 M200 F202 M203 K213 H249 Y258 Y300 3.4.19.12 Q93009 29056421 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEK 5vsk A 3.33 BS01 9HS A 1 Y224 H294 D295 V296 Q297 Q351 Q405 M407 R408 F409 K420 H456 Y465 Y514 Y17 H87 D88 V89 Q90 Q144 Q198 M200 R201 F202 K206 H242 Y251 Y292 3.4.19.12 Q93009 29056421 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEA 5vsk A 3.33 BS02 ZN A 1 C300 D349 H403 C93 D142 H196 3.4.19.12 Q93009 29056421 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEA 5vsk A 3.33 BS03 ZN A 2 H464 D481 H250 D267 3.4.19.12 Q93009 29056421 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEA 5vsk B 3.33 BS01 9HS B 1 Y224 D295 V296 Q297 L406 M407 R408 F409 M410 K420 H456 H461 Y465 Y514 Y17 D82 V83 Q84 L168 M169 R170 F171 M172 K182 H218 H223 Y227 Y268 3.4.19.12 Q93009 29056421 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIDYRSDDYYDIQLSIKGKKNIFESFVDYVAVEQEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIE 5vsk B 3.33 BS02 ZN B 1 C300 H403 C87 H165 3.4.19.12 Q93009 29056421 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIDYRSDDYYDIQLSIKGKKNIFESFVDYVAVEQEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIE 5vsk B 3.33 BS03 ZN B 2 H464 D481 H226 D243 3.4.19.12 Q93009 29056421 KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIDYRSDDYYDIQLSIKGKKNIFESFVDYVAVEQEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIE 5w3d A 2.79 BS01 ADP A 1 R354 R356 P357 T436 G437 S438 G439 K440 T441 Y442 R63 R65 P66 T138 G139 S140 G141 K142 T143 Y144 P20480 29123223 MHAALSTEVVHLRQRTEELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPESVGVIPRTVDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSNITEETVLDPNHLRHLMHTAKMNRERSSRSHAVTKLELIGRHAEKQEISVGSINLVDLAGSESPINRSLSELTNVILALLQKQDHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCK 5w3d B 2.79 BS01 MG B 1 T441 S551 T145 S221 P20480 29123223 MHAALSTEVVHLRQRTEELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDAMGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPESVGVIPRTVDLLFDSIRGYRNGWEYEIKATFLEIYNEVLYDLLTEETVLDPNHLRHLMHTAKMNRASSRSHAVTKLELIGRHSVGSINLVDLAGSESPNRSLSELTNVILALLQKPYRNSKLTHLLMPNSKTLMFINVSPFQDCFQESVKSLRFAASVNS 5w3d B 2.79 BS02 ADP B 1 R354 R356 P357 G437 S438 G439 K440 T441 Y442 R63 R65 P66 G141 S142 G143 K144 T145 Y146 P20480 29123223 MHAALSTEVVHLRQRTEELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDAMGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPESVGVIPRTVDLLFDSIRGYRNGWEYEIKATFLEIYNEVLYDLLTEETVLDPNHLRHLMHTAKMNRASSRSHAVTKLELIGRHSVGSINLVDLAGSESPNRSLSELTNVILALLQKPYRNSKLTHLLMPNSKTLMFINVSPFQDCFQESVKSLRFAASVNS 5w3u A 2.50 BS02 CO A 1 H22 K137 H170 H199 D256 H21 K136 H169 H198 D255 3.1.8.1 Q97VT7 29196634 RIPLVGKDSIESKDIGFTLIHEHLRAFSEAVRQQWPHLYNEDEEFRNAVNEVKRAMQFGVKTIVDPTVMGLGRDTRFMEKVVKATGINLVAGTGIWIFIDLPFYFLNRSIDEIADLFIHDIKEGIQGTPNKAGFVKIAADEPGITKDVEKVIRAAAIANKETKVPIITHSNAHNNTGLEQQRILTEEGVDPGKILIGHLGDTDNIDYIKKIADKGSFIGLDRYGVDLFLPVDKRNETTLRLIKDGYSDKIMISHDYWSITLIFEDTIPFLKRNGVNEEVIATIFKENPKKFFS 5w3u B 2.50 BS02 CO B 1 W97 K137 H170 H199 W97 K137 H170 H199 3.1.8.1 Q97VT7 29196634 MRIPLVGKDSIESKDIGFTLIHEHLRAFSEAVRQQWPHLYNEDEEFRNAVNEVKRAMQFGVKTIVDPTVMGLGRDTRFMEKVVKATGINLVAGTGIWIFIDLPFYFLNRSIDEIADLFIHDIKEGIQGTPNKAGFVKIAADEPGITKDVEKVIRAAAIANKETKVPIITHSNAHNNTGLEQQRILTEEGVDPGKILIGHLGDTDNIDYIKKIADKGSFIGLDRYGVDLFLPVDKRNETTLRLIKDGYSDKIMISHDYCPRWSITLIFEDTIPFLKRNGVNEEVIATIFKENPKKFFS 5w3u D 2.50 BS02 CO D 1 W97 K137 H170 H199 W97 K137 H170 H199 3.1.8.1 Q97VT7 29196634 MRIPLVGKDSIESKDIGFTLIHEHLRAFSEAVRQQWPHLYNEDEEFRNAVNEVKRAMQFGVKTIVDPTVMGLGRDTRFMEKVVKATGINLVAGTGIWIFIDLPFYFLNRSIDEIADLFIHDIKEGIQGTPNKAGFVKIAADEPGITKDVEKVIRAAAIANKETKVPIITHSNAHNNTGLEQQRILTEEGVDPGKILIGHLGDTDNIDYIKKIADKGSFIGLDRYGVDLFLPVDKRNETTLRLIKDGYSDKIMISHDYCSITLIFEDTIPFLKRNGVNEEVIATIFKENPKKFFS 5wbh D 1.75 BS01 III W 1 L2031 E2032 S2035 R2036 F2039 W2101 D2102 Y2105 F2108 L10 E11 S14 R15 F18 W80 D81 Y84 F87 2.7.11.1 P42345 LWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISK 5wbj A 3.00 BS01 III T 1 R103 R336 T348 F368 R369 L372 A375 Q470 L472 L473 R478 Y507 K510 L511 Q513 R43 R276 T288 F308 R309 L312 A315 Q410 L412 L413 R418 Y447 K450 L451 Q453 Q93YQ1 ATSMAYLPQTIVLCELRHDASEASAPLGTSEIVLVPKWRLKERMKTGCVALVLCLNITVDPPDVIKISPCARIEAWIDPFSMAPPKALETIGKNLSTQYERWQPRARYKVQLDPTVDEVRKLCLTCRKYAKTERVLFHYNGHGVPKPTANGEIWVFNKSYTQYIPLPISELDSWLKTPSIYVFDCSAARMILNAFAELHDWGSSGSSGSSRDCILLAACDVHETLPQSVEFPADVFTSCLTTPIKMALKWFCRRSLLKEIIDESLIDRIPGRQNDRKTLLGELNWIFTAVTDTIAWNVLPHELFQRLFRQDLLVASLFRNFLLAERIMRSANCNPISHPMLPPTHQHHMWDAWDMAAEICLSQLPQLVLDPSTEFQPSPFFTEQLTAFEVWLDHGSEHKKPPEQLPIVLQVLLSQCHRFRALVLLGRFLDMGSWAVDLALSVGIFPYVLKLLQTTTNELRQILVFIWTKILALDKSCQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFVLAVIVDGHRRGQEACLEANLIGVCLGHLEEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLAPLLSEPQPEVRAAAVFALGTLLDEFDDDEKIRAEDAIIKSLLDVVSDGSPLVRAEVAVALARFAFGHKQHLKLAAASYWAVYSQCVRAMFALAKDPSPRIASLGRRVLSIIGIEERSLLPLSTIYGWSCGHFSKPLSQEIAAKREEKEKFALEHIAKCQHSSISKLNNNPIANWDTRFETGTKTALLHPFSPIVVAADENERIRVWNYEEATLLNGFDNHDFPDKGISKLCLINELDDSLLLVASCDGSVRIWKNYATKGKQKLVTGFSSIQLNAVVDWQQQSGYLYASGETSTVTLWDLEKEQLVRSVPSESECGVTALSASQVHGGQLAAGFADGSLRLYDVRSPEPLVCATRPHQKVERVVGLSFQPGLDPAKVVSASQAGDIQFLDLRTTRDTYLTIDAHRGSLTALAVHRHAPIIASGSAKQLIKVFSLQGEQLGIIRYYPSFMAQKIGSVSCLTFHPYQVLLAAGAADSFVSIYTHD 5wbk A 3.11 BS01 III T 1 R103 R336 T348 D352 R369 L372 A375 R379 L469 Q470 L473 R478 P506 Y507 K510 R43 R271 T283 D287 R304 L307 A310 R314 L404 Q405 L408 R413 P441 Y442 K445 Q93YQ1 ATSMAYLPQTIVLCELRHDASEASAPLGTSEIVLVPKWRLKERMKTGCVALVLCLNITVDPPDVCARIEAWIDPFSMAPPKALETIGKNLSTQYERWQPRARYKVQLDPTVDEVRKLCLTCRKYAKTERVLFHYNGHGVPKPTANGEIWVFNKSYTQYIPLPISELDSWLKTPSIYVFDCSAARMILNAFAELHDWGSSGSSGSSRDCILLAACDVHETLPQSVEFPADVFTSCLTTPIKMALKWFCRRSLLKEIIDESLIDRIPGRQNDRKTLLGELNWIFTAVTDTIAWNVLPHELFQRLFRQDLLVASLFRNFLLAERIMRSANCNPISHPMLPPTHQHHMWDAWDMAAEICLSQLPQLVLDPSTEFQPSPFFTEQLTAFEVWLDHGSEHKKPPEQLPIVLQVLLSQCHRFRALVLLGRFLDMGSWAVDLALSVGIFPYVLKLLQTTTNELRQILVFIWTKILALDKSCQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFVLAVIVDGHRRGQEACLEANLIGVCLGHLEEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLAPLLSEPQPEVRAAAVFALGTLLDEFDDDEKIRAEDAIIKSLLDVVSDGSPLVRAEVAVALARFAFGHKQHLKLAAASYWAVYSQCVRAMFALAKDPSPRIASLGRRVLSIIGIEERSLLPLSTIYGWSCGHFSKPLSQEIAAKREEKEKFALEHIAKCQHSSISKLNNNPIANWDTRFETGTKTALLHPFSPIVVAADENERIRVWNYEEATLLNGFDNHDFPDKGISKLCLINELDDSLLLVASCDGSVRIWKNYATKGKQKLVTGFSSIQLNAVVDWQQQSGYLYASGETSTVTLWDLEKEQLVRSVPSESECGVTALSASQVHGGQLAAGFADGSLRLYDVRSPEPLVCATRPHQKVERVVGLSFQPGLDPAKVVSASQAGDIQFLDLRTTRDTYLTIDAHRGSLTALAVHRHAPIIASGSAKQLIKVFSLQGEQLGIIRYYPSFMAQKIGSVSCLTFHPYQVLLAAGAADSFVSIYTHD 5wbl A 3.35 BS01 III T 1 R103 R336 T348 D352 F368 R369 L372 Q470 L472 L473 P506 Y507 K510 R43 R271 T283 D287 F303 R304 L307 Q405 L407 L408 P441 Y442 K445 Q93YQ1 ATSMAYLPQTIVLCELRHDASEASAPLGTSEIVLVPKWRLKERMKTGCVALVLCLNITVDPPDVCARIEAWIDPFSMAPPKALETIGKNLSTQYERWQPRARYKVQLDPTVDEVRKLCLTCRKYAKTERVLFHYNGHGVPKPTANGEIWVFNKSYTQYIPLPISELDSWLKTPSIYVFDCSAARMILNAFAELHDWGSSGSSGSSRDCILLAACDVHETLPQSVEFPADVFTSCLTTPIKMALKWFCRRSLLKEIIDESLIDRIPGRQNDRKTLLGELNWIFTAVTDTIAWNVLPHELFQRLFRQDLLVASLFRNFLLAERIMRSANCNPISHPMLPPTHQHHMWDAWDMAAEICLSQLPQLVLDPSTEFQPSPFFTEQLTAFEVWLDHGSEHKKPPEQLPIVLQVLLSQCHRFRALVLLGRFLDMGSWAVDLALSVGIFPYVLKLLQTTTNELRQILVFIWTKILALDKSCQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFVLAVIVDGHRRGQEACLEANLIGVCLGHLEEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLAPLLSEPQPEVRAAAVFALGTLLDEFDDDEKIRAEDAIIKSLLDVVSDGSPLVRAEVAVALARFAFGHKQHLKLAAASYWAVYSQCVRAMFALAKDPSPRIASLGRRVLSIIGIEERSLLPLSTIYGWSCGHFSKPLSQEIAAKREEKEKFALEHIAKCQHSSISKLNNNPIANWDTRFETGTKTALLHPFSPIVVAADENERIRVWNYEEATLLNGFDNHDFPDKGISKLCLINELDDSLLLVASCDGSVRIWKNYATKGKQKLVTGFSSIQLNAVVDWQQQSGYLYASGETSTVTLWDLEKEQLVRSVPSESECGVTALSASQVHGGQLAAGFADGSLRLYDVRSPEPLVCATRPHQKVERVVGLSFQPGLDPAKVVSASQAGDIQFLDLRTTRDTYLTIDAHRGSLTALAVHRHAPIIASGSAKQLIKVFSLQGEQLGIIRYYPSFMAQKIGSVSCLTFHPYQVLLAAGAADSFVSIYTHD 5wbu B 3.42 BS01 III R 1 H2028 S2035 R2036 Y2038 F2039 V2094 T2098 W2101 Y2105 F2108 R2109 L2115 H592 S599 R600 Y602 F603 V658 T662 W665 Y669 F672 R673 L679 2.7.11.1 P42345 29236692 ERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 5wbu D 3.42 BS01 III P 1 Q164 L165 I166 P167 Y195 V196 W197 P212 K213 T214 Q157 L158 I159 P160 Y188 V189 W190 P205 K206 T207 Q9BVC4 29236692 VGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSV 5wbu A 3.42 BS01 III Q 1 H2028 S2035 Y2038 F2039 T2098 W2101 Y2105 F2108 R2109 L2115 K2166 H586 S593 Y596 F597 T656 W659 Y663 F666 R667 L673 K724 2.7.11.1 P42345 29236692 ERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 5wbu C 3.42 BS01 III O 1 L165 I166 P167 Y195 V196 W197 P212 K213 T214 K215 L158 I159 P160 Y188 V189 W190 P205 K206 T207 K208 Q9BVC4 29236692 VGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSV 5wbx B 1.90 BS01 AJY R 1 A477 L480 V481 A83 L86 V87 Q9H2S1 29214998 GRKLELTKAEKHVHAFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQLE 5wbx R 1.90 BS03 AJY R 1 I27 L32 M51 E54 V55 I63 F68 M71 M72 K75 I26 L31 M50 E53 V54 I62 F67 M70 M71 K74 P0DP23 29214998 AALTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 5wby C 3.10 BS01 III O 1 Q164 L165 I166 P167 Y195 W197 P212 K213 T214 Q157 L158 I159 P160 Y188 W190 P205 K206 T207 Q9BVC4 29236692 VGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSV 5wc5 R 2.30 BS03 AJV R 1 F19 M51 V55 F68 M71 F18 M50 V54 F67 M70 P0DP23 29214998 AALTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 5we0 A 2.30 BS01 III B 1 F18 Y24 M26 S31 N35 L38 R39 L41 G42 Y43 M47 C48 H49 M52 M56 F60 Y63 C64 N66 Q88 L90 E92 L95 N98 R102 F18 Y24 M26 S31 N35 L38 R39 L41 G42 Y43 M47 C48 H49 M52 M56 F60 Y63 C64 N66 Q74 L76 E78 L81 N84 R88 O13852 29149597 SNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLDPSQQILWEYSLISNALERLENIELERQNCMRELLNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKML 5we0 A 2.30 BS02 III C 1 T132 L133 E136 L140 C143 R150 E181 L185 Y199 H203 M207 K211 F212 V215 R218 Q221 C222 L225 T108 L109 E112 L116 C119 R126 E157 L161 Y175 H179 M183 K187 F188 V191 R194 Q197 C198 L201 O13852 29149597 SNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLDPSQQILWEYSLISNALERLENIELERQNCMRELLNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKML 5we0 D 2.30 BS01 III E 1 F18 Y24 M26 R28 S31 N35 L38 R39 L41 G42 Y43 K45 M47 C48 H49 M52 P53 F60 Y63 C64 Q88 I89 L90 E92 L95 N98 R102 F18 Y24 M26 R28 S31 N35 L38 R39 L41 G42 Y43 K45 M47 C48 H49 M52 P53 F60 Y63 C64 Q72 I73 L74 E76 L79 N82 R86 O13852 29149597 SNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLSQQILWEYSLISNALERLENIELERQNCMRELNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKM 5we0 D 2.30 BS02 III F 1 T132 L133 E136 R150 K180 E181 A184 L185 R187 K195 Y199 H203 K211 F212 V215 R218 C222 L225 T105 L106 E109 R123 K153 E154 A157 L158 R160 K168 Y172 H176 K184 F185 V188 R191 C195 L198 O13852 29149597 SNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLSQQILWEYSLISNALERLENIELERQNCMRELNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKM 5we0 G 2.30 BS01 III H 1 F18 Y24 M26 S31 N35 L38 R39 L41 G42 Y43 M47 C48 H49 M52 F60 Y63 C64 Q88 I89 E92 L95 N98 R102 F18 Y24 M26 S31 N35 L38 R39 L41 G42 Y43 M47 C48 H49 M52 F60 Y63 C64 Q74 I75 E78 L81 N84 R88 O13852 29149597 SNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLDPSQQILWEYSLISNALERLENIELERQNCMRELLNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKMLT 5we0 G 2.30 BS02 III I 1 L128 T132 L133 E136 L140 C143 R150 E181 Y199 K211 F212 V215 R218 Q221 C222 L225 L244 L104 T108 L109 E112 L116 C119 R126 E154 Y172 K184 F185 V188 R191 Q194 C195 L198 L217 O13852 29149597 SNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLDPSQQILWEYSLISNALERLENIELERQNCMRELLNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKMLT 5we0 J 2.30 BS02 III L 1 L128 N129 T132 L133 E136 C143 R150 N178 L185 Y199 H203 K211 F212 R218 C222 L225 L101 N102 T105 L106 E109 C116 R123 N151 L158 Y172 H176 K184 F185 R191 C195 L198 O13852 29149597 SNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLSQQILWEYSLISNALERLENIELERQNCMRELNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKMLT 5we1 A 3.20 BS01 III B 1 L38 G42 M47 C48 H49 K51 M52 M56 F60 Y63 C64 N66 Q88 L90 E92 L95 N98 R102 L7 G11 M16 C17 H18 K20 M21 M25 F29 Y32 C33 N35 Q40 L42 E44 L47 N50 R54 O13852 29149597 SIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSSQQILWEYSLISNALERLENIELERQNCMRLLNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQ 5we1 C 3.20 BS01 III B 1 I33 V34 Y40 I3 V4 Y10 O13852 29149597 SSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLSQQILWEYSLISNALERLENIELERQNCMRLLNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQ 5we1 D 3.20 BS01 ZN C 1 C479 C482 H488 C2 C5 H11 O14246 29149597 ACEMCRLGLPHGSFFELLRDWKKIEEFRNK 5we2 C 2.50 BS01 III D 1 F18 Y24 M26 S31 N35 L38 R39 L41 G42 Y43 K45 M47 C48 H49 M52 M56 F60 Y63 C64 N66 Q87 Q88 I89 L90 E92 S94 L95 N98 R102 F18 Y24 M26 S31 N35 L38 R39 L41 G42 Y43 K45 M47 C48 H49 M52 M56 F60 Y63 C64 N66 Q85 Q86 I87 L88 E90 S92 L93 N96 R100 O13852 29149597 SNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLDPFQNLPITQTQPDSQQILWEYSLISNALERLENIELERQNCMRENKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKM 5we2 C 2.50 BS02 III F 1 K139 S142 E181 M207 K125 S128 E167 M193 O13852 29149597 SNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLDPFQNLPITQTQPDSQQILWEYSLISNALERLENIELERQNCMRENKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKM 5wsh A 2.00 BS01 III C 1 M5 Y7 E63 R65 K66 H70 T73 D77 Y84 Y99 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 M5 Y7 E63 R65 K66 H70 T73 D77 Y84 Y99 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE 5wtt H 2.70 BS01 III P 1 S34 H36 W48 Y51 H53 T100 I101 G104 S105 S34 H36 W48 Y51 H53 T100 I101 G104 S105 DVQLQESGPDLVKPSQSPSLTCTVTGYSITSDYSWHWIRQFPGDKLEWMGYIHYSGSTNYNPSLKSRISITRDTSKNQFFLQLSSVTIEDTATYYCARGTIYEGSLDYWGQGTTLTVSSAKTTPPSVYPLAPGSSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR 5wtt L 2.70 BS01 III P 1 Y31 Y37 G96 T97 H98 F99 Q101 Y31 Y37 G96 T97 H98 F99 Q101 DVVMTQTPLTLSVTIGQPASISCKSSQSLLYSDGKTYLNWLFQRPGQSPKRLIYLVSKLDSGVPDRFTGSGSGIDFKLKISRVEAEDLGVYYCVQGTHFPQTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNR 5wtt A 2.70 BS01 III C 1 S34 H36 W48 Y51 H53 N59 T100 I101 G104 S105 L106 S34 H36 W48 Y51 H53 N59 T100 I101 G104 S105 L106 DVQLQESGPDLVKPSQSPSLTCTVTGYSITSDYSWHWIRQFPGDKLEWMGYIHYSGSTNYNPSLKSRISITRDTSKNQFFLQLSSVTIEDTATYYCARGTIYEGSLDYWGQGTTLTVSSAKTTPPSVYPLAPGNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDC 5wtt B 2.70 BS01 III C 1 Y31 Y37 G96 H98 F99 Q101 Y31 Y37 G96 H98 F99 Q101 DVVMTQTPLTLSVTIGQPASISCKSSQSLLYSDGKTYLNWLFQRPGQSPKRLIYLVSKLDSGVPDRFTGSGSGIDFKLKISRVEAEDLGVYYCVQGTHFPQTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNR 5wyq A 2.16 BS01 SAM A 1 Y91 L92 S93 P94 Q95 G118 Y120 E121 W136 S137 I138 G139 Y141 V142 L143 S144 G145 G146 P149 Y89 L90 S91 P92 Q93 G116 Y118 E119 W134 S135 I136 G137 Y139 V140 L141 S142 G143 G144 P147 2.1.1.228 Q02RL6 SMLWVGVVSIFPEMFRAISDYGITSRAVKQGLLTLTCWNPRVYTEDRHQTVDDRPFGGGPGMVMKIKPLEGALADARQAAGGRKAKVIYLSPQGRQLTQAGVRELAEEEALILIAGRYEGIDERFIEEHVDEEWSIGDYVLSGGELPAMVLVDAVTRLLPGALFTDGLLDCPHYTRPEVYADKRVPEVLLSGNHEHIRRWRLQQALGRTWERRADLLDSRSLSGEEQKLLAEYIRQRD 5wyq A 2.16 BS02 SAM B 1 D182 H185 D170 H173 2.1.1.228 Q02RL6 SMLWVGVVSIFPEMFRAISDYGITSRAVKQGLLTLTCWNPRVYTEDRHQTVDDRPFGGGPGMVMKIKPLEGALADARQAAGGRKAKVIYLSPQGRQLTQAGVRELAEEEALILIAGRYEGIDERFIEEHVDEEWSIGDYVLSGGELPAMVLVDAVTRLLPGALFTDGLLDCPHYTRPEVYADKRVPEVLLSGNHEHIRRWRLQQALGRTWERRADLLDSRSLSGEEQKLLAEYIRQRD 5wyq B 2.16 BS01 SAM A 1 S175 D182 H185 S165 D172 H175 2.1.1.228 Q02RL6 SMLWVGVVSIFPEMFRAISDYGITSRAVKQGLLTLTCWNPRVYTEDRHQTVDDRPFGGGPGMVMKIKPLEGALADARQAAGGRKAKVIYLSPQGRQLTQAGVRELAEEEALILIAGRYEGIDERFIEEHVDEEWSIGDYVLSGGELPAMVLVDAVTRLLPGALDSFTDGLLDCPHYTRPEVYADKRVPEVLLSGNHEHIRRWRLQQALGRTWERRADLLDSRSLSGEEQKLLAEYIRQRD 5wyq B 2.16 BS02 SAM B 1 Y91 L92 S93 P94 Q95 G118 Y120 E121 I138 G139 Y141 L143 G145 G146 P149 Y89 L90 S91 P92 Q93 G116 Y118 E119 I136 G137 Y139 L141 G143 G144 P147 2.1.1.228 Q02RL6 SMLWVGVVSIFPEMFRAISDYGITSRAVKQGLLTLTCWNPRVYTEDRHQTVDDRPFGGGPGMVMKIKPLEGALADARQAAGGRKAKVIYLSPQGRQLTQAGVRELAEEEALILIAGRYEGIDERFIEEHVDEEWSIGDYVLSGGELPAMVLVDAVTRLLPGALDSFTDGLLDCPHYTRPEVYADKRVPEVLLSGNHEHIRRWRLQQALGRTWERRADLLDSRSLSGEEQKLLAEYIRQRD 5wyr A 2.45 BS01 SFG A 1 Y91 L92 S93 P94 Q95 G118 Y120 E121 G122 W136 S137 I138 G139 Y141 L143 G145 G146 P149 Y89 L90 S91 P92 Q93 G116 Y118 E119 G120 W134 S135 I136 G137 Y139 L141 G143 G144 P147 2.1.1.228 Q02RL6 SMLWVGVVSIFPEMFRAISDYGITSRAVKQGLLTLTCWNPRVYTEDRHQTVDDRPFGGGPGMVMKIKPLEGALADARQAAGGRKAKVIYLSPQGRQLTQAGVRELAEEEALILIAGRYEGIDERFIEEHVDEEWSIGDYVLSGGELPAMVLVDAVTRLLPGALGEDSFTDGLLDCPHYTRPEVYADKRVPEVLLSGNHEHIRRWRLQQALGRTWERRADLLDSRSLSGEEQKLLAEYIRQRD 5wyr A 2.45 BS02 SFG B 1 R159 L165 S175 D182 R157 L163 S167 D174 2.1.1.228 Q02RL6 SMLWVGVVSIFPEMFRAISDYGITSRAVKQGLLTLTCWNPRVYTEDRHQTVDDRPFGGGPGMVMKIKPLEGALADARQAAGGRKAKVIYLSPQGRQLTQAGVRELAEEEALILIAGRYEGIDERFIEEHVDEEWSIGDYVLSGGELPAMVLVDAVTRLLPGALGEDSFTDGLLDCPHYTRPEVYADKRVPEVLLSGNHEHIRRWRLQQALGRTWERRADLLDSRSLSGEEQKLLAEYIRQRD 5wyr B 2.45 BS01 SFG A 1 D169 D174 S175 D182 D167 D172 S173 D180 2.1.1.228 Q02RL6 SMLWVGVVSIFPEMFRAISDYGITSRAVKQGLLTLTCWNPRVYTEDRHQTVDDRPFGGGPGMVMKIKPLEGALADARQAAGGRKAKVIYLSPQGRQLTQAGVRELAEEEALILIAGRYEGIDERFIEEHVDEEWSIGDYVLSGGELPAMVLVDAVTRLLPGALGHADSAEEDSFTDGLLDCPHYTRPEVYADKRVPEVLLSGNHEHIRRWRLQQALGRTWERRADLLDSRSLSGEEQKLLAEYIRQRD 5wyr B 2.45 BS02 SFG B 1 Y91 L92 S93 P94 G118 Y120 E121 I138 G139 Y141 V142 L143 S144 G145 G146 P149 Y89 L90 S91 P92 G116 Y118 E119 I136 G137 Y139 V140 L141 S142 G143 G144 P147 2.1.1.228 Q02RL6 SMLWVGVVSIFPEMFRAISDYGITSRAVKQGLLTLTCWNPRVYTEDRHQTVDDRPFGGGPGMVMKIKPLEGALADARQAAGGRKAKVIYLSPQGRQLTQAGVRELAEEEALILIAGRYEGIDERFIEEHVDEEWSIGDYVLSGGELPAMVLVDAVTRLLPGALGHADSAEEDSFTDGLLDCPHYTRPEVYADKRVPEVLLSGNHEHIRRWRLQQALGRTWERRADLLDSRSLSGEEQKLLAEYIRQRD 5x3s B 2.90 BS01 III D 1 W414 D416 Y417 Y485 H489 L490 L491 R516 H538 K540 R557 W44 D46 Y47 Y115 H119 L120 L121 R146 H168 K170 R187 2.7.11.21 Q07832 29191835 ECHLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS 5x3s A 2.90 BS01 III C 1 W414 D416 Y417 Y485 H489 L490 L491 H538 K540 W44 D46 Y47 Y115 H119 L120 L121 H168 K170 2.7.11.21 Q07832 29191835 ECHLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS 5xaf B 2.55 BS04 84F B 1 G237 V238 C241 L242 L248 A250 D251 L255 N258 M259 V315 A316 A317 I318 N350 K352 T353 G235 V236 C239 L240 L246 A248 D249 L253 N256 M257 V307 A308 A309 I310 N342 K344 T345 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5xaf D 2.55 BS01 GDP D 1 G10 Q11 C12 Q15 A99 S140 G143 G144 T145 G146 V177 E183 N206 Y224 N228 G10 Q11 C12 Q15 A97 S138 G141 G142 T143 G144 V175 E181 N204 Y222 N226 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5xaf D 2.55 BS03 84F D 1 G237 V238 C241 L242 L248 A250 D251 K254 L255 N258 M259 A316 A317 I318 N350 K352 A354 I378 G235 V236 C239 L240 L246 A248 D249 K252 L253 N256 M257 A304 A305 I306 N338 K340 A342 I358 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5xaf F 2.55 BS01 MG F 1 D200 R222 N242 D318 D153 R175 N192 D267 E1BQ43 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSCTWFPESYVIYPTDEREVFLAAYNGNVWIAKSISSEASELLDFIHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSADKTCHLTNHCIQKEYSNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKL 5xaf F 2.55 BS02 ACP F 1 K74 P95 Q183 K184 L186 K198 H239 L240 T241 M320 I330 E331 K74 P93 Q136 K137 L139 K151 H189 L190 T191 M269 I279 E280 E1BQ43 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSCTWFPESYVIYPTDEREVFLAAYNGNVWIAKSISSEASELLDFIHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSADKTCHLTNHCIQKEYSNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKL 5xgd A 2.80 BS01 GTP A 1 L413 Q415 F416 K417 N420 H425 G428 D429 R451 G454 D455 K525 R529 L601 L164 Q166 F167 K168 N171 H176 G179 D180 R202 G205 D206 K276 R280 L352 Q9I580 29109186 DAERERAQITLASIGDGVITADTQGGISYLNPAAEQMTNWTLDKARGLPLASLFRIVDESEQILSGEIDGGREHSKLVLRHDGSSVPVTLVGAPIHRGAEITGVVLVLHDMTRERQYMARLSWQATHDALTGLTNRREFEYRLQIALERLERNSGRHALMFLDLDQFKLVNDTCGHAAGDELLRQVCTLLQQGLREGDTLARLGGDEFGILLENCPAEKAVEIADHLRKTIQDLHFTWSGQPFNCTVSVGLVHLLPGISTLEEALRSADMACYMAKEKGRNRVQVFHQDDVELSMRFGEMTWVQRIHLALEEDRFSLYAQPIVPLGEGAEEGLHVELLLRLRDEGGRLVPPLSFIPAAERYGLMTLIDRWVVENAFRTLVERAQDPRAEPIGTCAINLSGATIGDESFLQFLTELFARYRIPPQTICFEVTETVAVANLASAIRFINELKDTGCRFSLDDFCAGMSSFIYLKHLPVDYLKIDGSFVKDMLEDPIDRAMVQVINHIGHVMGKRTIAEFVETVEVMEALREIGIDYAQGLAIGAPLPFSR 5xgd A 2.80 BS02 MG A 1 D412 L413 D455 K525 D163 L164 D206 K276 Q9I580 29109186 DAERERAQITLASIGDGVITADTQGGISYLNPAAEQMTNWTLDKARGLPLASLFRIVDESEQILSGEIDGGREHSKLVLRHDGSSVPVTLVGAPIHRGAEITGVVLVLHDMTRERQYMARLSWQATHDALTGLTNRREFEYRLQIALERLERNSGRHALMFLDLDQFKLVNDTCGHAAGDELLRQVCTLLQQGLREGDTLARLGGDEFGILLENCPAEKAVEIADHLRKTIQDLHFTWSGQPFNCTVSVGLVHLLPGISTLEEALRSADMACYMAKEKGRNRVQVFHQDDVELSMRFGEMTWVQRIHLALEEDRFSLYAQPIVPLGEGAEEGLHVELLLRLRDEGGRLVPPLSFIPAAERYGLMTLIDRWVVENAFRTLVERAQDPRAEPIGTCAINLSGATIGDESFLQFLTELFARYRIPPQTICFEVTETVAVANLASAIRFINELKDTGCRFSLDDFCAGMSSFIYLKHLPVDYLKIDGSFVKDMLEDPIDRAMVQVINHIGHVMGKRTIAEFVETVEVMEALREIGIDYAQGLAIGAPLPFSR 5xge A 3.31 BS01 C2E A 1 Q569 E585 L587 L588 R589 D617 V620 N646 D708 E765 F766 E768 G786 L787 Q320 E336 L338 L339 R340 D368 V371 N397 D459 E516 F517 E519 G537 L538 Q9I580 29109186 DAERERAQITLASIGDGVITADTQGGISYLNPAAEQMTNWTLDKARGLPLASLFRIVDLIEQILSGEIDGGREHSKLVLRHDGSSVPVTLVGAPIHRGAEITGVVLVLHDMTRERQYMARLSWQATHDALTGLTNRREFEYRLQIALERLERNSGRHALMFLDLDQFKLVNDTCGHAAGDELLRQVCTLLQQGLREGDTLARLGGDEFGILLENCPAEKAVEIADHLRKTIQDLHFTWSGQPFNCTVSVGLVHLLPGISTLEEALRSADMACYMAKEKGRNRVQVFHQDDVELSMRFGEMTWVQRIHLALEEDRFSLYAQPIVPLGEGAEEGLHVELLLRLRDEGGRLVPPLSFIPAAERYGLMTLIDRWVVENAFRTLVERAQDPRAEPIGTCAINLSGATIGDESFLQFLTELFARYRIPPQTICFEVTETVAVANLASAIRFINELKDTGCRFSLDDFCAGMSSFIYLKHLPVDYLKIDGSFVKDMLEDPIDRAMVQVINHIGHVMGKRTIAEFVETVEVMEALREIGIDYAQGLAIGAPLPFSR 5xh2 A 1.20 BS01 NPO A 1 M132 W156 I179 M133 W157 I180 3.1.1.101 A0A0K8P6T7 MNPYARGPNPTAASLEASAGPFTVRSFTVSRPSGYGAGTVYYPTNAGGTVGAIAIVPGYTARQSSIKWWGPRLASHGFVVITIDTNSTLDQPSSRSSQQMAALGQVASLNGTSSSPIYGKVDTARMGVMGWAMGGGGSLISAANNPSLKAAAPQAPWDSSTNFSSVTVPTLIFACENDSIAPVNSSALPIYDSMSRNAKQFLEINGGSHSCANSGNSNQALIGKKGVAWMKRFMDNDTRYSTFACENPNSTRVSDFRTANC 5xh3 A 1.30 BS01 856 A 1 G57 Y58 W130 A131 M132 W156 I179 H208 G57 Y58 W130 A131 M132 W156 I179 H208 3.1.1.101 A0A0K8P6T7 NPYARGPNPTAASLEASAGPFTVRSFTVSRPSGYGAGTVYYPTNAGGTVGAIAIVPGYTARQSSIKWWGPRLASHGFVVITIDTNSTLDQPSSRSSQQMAALGQVASLNGTSSSPIYGKVDTARMGVMGWAMGGGGSLISAANNPSLKAAAPQAPWDSSTNFSSVTVPTLIFACENDSIAPVNSSALPIYDSMSRNAKQFLEINGGSHSCANSGNSNQALIGKKGVAWMKRFMDNDTRYSTFACENPNSTRVSDFRTANCS 5xhg A 1.76 BS01 OAZ A 1 V150 A153 K155 H189 V150 A153 K155 H189 28727448 DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALKSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 5xt5 D 2.34 BS01 ZN D 1 D43 C66 C128 D38 C61 C123 2.-.-.- O32163 NLDTLYRQVIMDHYKNPRNKGVLNDSIVVDMNNPTCGDRIRLTMKLDGDIVEDAKFEGEGCSISMASASMMTQAIKGKDIETALSMSKIFSDMMQGKEYDDSIDLGDIEALQGVSKFPARIKCATLSWKALEKGVAK 5xt5 A 2.34 BS01 PLP A 1 T92 T93 H121 A123 D198 A200 Q201 S221 H223 K224 T93 T94 H122 A124 D199 A201 Q202 S222 H224 K225 2.8.1.7 O32164 HMNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQYNSNVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDEISRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVLDAEGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLVEALQKTKEYFTN 5xt6 A 3.50 BS01 PDA A 1 A28 A29 T92 T93 H121 N173 D198 A200 Q201 S221 H223 K224 R356 H360 R376 A29 A30 T93 T94 H122 N174 D199 A201 Q202 S222 H224 K225 R357 H361 R377 2.8.1.7 O32164 HMNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQYNSNVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDEISRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVLDAEGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLVEALQKTKEYFTN 5xt6 A 3.50 BS02 PDA B 1 R54 G274 T275 R55 G275 T276 2.8.1.7 O32164 HMNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQYNSNVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDEISRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVLDAEGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLVEALQKTKEYFTN 5xt6 B 3.50 BS01 PDA A 1 G274 T275 G274 T275 2.8.1.7 O32164 MNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQYNSNVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDEISRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVLDAEGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLVEALQKTKEYFTNV 5xt6 B 3.50 BS02 PDA B 1 A28 T92 T93 H121 N173 D198 A200 Q201 S221 H223 K224 R356 R376 A28 T92 T93 H121 N173 D198 A200 Q201 S221 H223 K224 R356 R376 2.8.1.7 O32164 MNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQYNSNVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDEISRHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVLDAEGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLVEALQKTKEYFTNV 5xxf A 3.10 BS01 III E 1 N129 T132 L133 E136 K139 C143 A146 R150 E181 Y199 M207 K211 F212 R218 Q221 C222 L225 N105 T108 L109 E112 K115 C119 A122 R126 E157 Y175 M183 K187 F188 R194 Q197 C198 L201 O13852 29160296 GSNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLDPDSQQILWEYSLISNALERLENIELERQNCMRENKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKMLTS 5xxf B 3.10 BS01 III F 1 N129 T132 L133 E136 C143 A146 R150 E181 M207 F212 R218 Q221 C222 L225 N111 T114 L115 E118 C125 A128 R132 E163 M189 F194 R200 Q203 C204 L207 O13852 29160296 GSNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSQILWEYSLISNALERLENIELERQNCMREDGLVKYTNELLLNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKMLTSN 5xzi A 2.65 BS01 HEM A 1 E4 M7 L10 N11 M33 P46 F61 G64 F65 T97 C98 C101 H102 Y105 R106 E4 M7 L10 N11 M33 P46 F61 G64 F65 T97 C98 C101 H102 Y105 R106 P0ABE7 28992705 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSATPPKLEDKSPDSPEMHDFRHGFWILIGQIHDALHLANEGKVKDAQEAAEHLKCTCNHCHQKYR 5xzj A 1.98 BS01 HEM A 1 E4 M7 M33 P45 F61 C98 C101 H102 R106 E4 M7 M33 P45 F61 C98 C101 H102 R106 P0ABE7 28992705 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSATPPKLEDKSPDSPEMHDFRHGFWILIGQIHDALHLANEGKVKDAQEAAEHLKTTCNHCHQKYR 5xzj B 1.98 BS01 HEM B 1 E4 M7 N11 P45 P46 F61 C98 C101 H102 R106 E4 M7 N11 P45 P46 F61 C98 C101 H102 R106 P0ABE7 28992705 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSATPPKLEDKSPDSPEMHDFRHGFWILIGQIHDALHLANEGKVKDAQEAAEHLKTTCNHCHQKYR 5xzj B 1.98 BS04 ZN B 3 E81 K83 E81 K83 P0ABE7 28992705 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSATPPKLEDKSPDSPEMHDFRHGFWILIGQIHDALHLANEGKVKDAQEAAEHLKTTCNHCHQKYR 5xzj C 1.98 BS01 HEM C 1 M7 N11 P45 P46 F61 C98 C101 H102 Y105 R106 M7 N11 P45 P46 F61 C98 C101 H102 Y105 R106 P0ABE7 28992705 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSATPPKLEDKSPDSPEMHDFRHGFWILIGQIHDALHLANEGKVKDAQEAAEHLKTTCNHCHQKYR 5xzj D 1.98 BS01 HEM D 1 M7 N11 P45 P46 F61 F65 C98 C101 H102 R106 M7 N11 P45 P46 F61 F65 C98 C101 H102 R106 P0ABE7 28992705 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSATPPKLEDKSPDSPEMHDFRHGFWILIGQIHDALHLANEGKVKDAQEAAEHLKTTCNHCHQKYR 5y2o A 1.80 BS01 8N6 A 1 F282 C285 S289 H323 Y327 I341 F363 M364 H449 Y473 F67 C70 S74 H108 Y112 I126 F148 M149 H234 Y258 P37231 29203903 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 5y2t A 1.70 BS01 8LX A 1 L255 G258 I281 F282 G284 C285 Q286 S289 H323 Y327 L330 I341 M348 M364 H449 L453 Y473 L49 G52 I66 F67 G69 C70 Q71 S74 H108 Y112 L115 I126 M133 M149 H234 L238 Y258 P37231 29203903 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDL 5y2t B 1.70 BS01 8LX B 1 L255 E259 F264 H266 R280 I281 F282 C285 Q286 S289 H323 Y327 I341 M348 F363 M364 H449 L453 L49 E53 F58 H60 R68 I69 F70 C73 Q74 S77 H111 Y115 I129 M136 F151 M152 H237 L241 P37231 29203903 SAMGSESADLRALAKHLYDSYIKSFPLTKAKARAILTGSPFVIYDMNSLMMGEDKIKFKHITKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKD 5y58 A 2.80 BS01 NUC X 1 T291 H292 E293 K294 V297 R298 Y299 K300 R316 F318 K333 M353 K422 N424 S425 H426 D453 R456 T255 H256 E257 K258 V261 R262 Y263 K264 R280 F282 K297 M317 K386 N388 S389 H390 D417 R420 3.6.4.12 P32807 IHEGILFCIELSETMFKESSDLEYKSPLLEILESLDELMSQLVITRPGTAIGCYFYYCNREDAKEGIYELFPLRDINATFMKKLNDLLEDLSSGRISLYDYFMFQQTGSEKQVRLSVLFTFMLDTFLEEIPGQKQLSNKRVFLFTDIDKPQEAQDIDERARLRRLTIDLFDNKVNFATFFIGYADKPFDNEFYSDILQLGDSEFDGPSTKPIDAKYIKSRILRKKEVKRIMFQCPLILDEKTNFIVGVKGYTMYTHEKAGVRYKLVYEHEDIRQEAYSKRKFLNPITGEDVTGKTVKVYPYGDLDINLSDSQDQIVMEAYTQKDAFLKIIGFRSSSKSIHYFNNIDKSSFIVPDEAKYEGSIRTLASLLKILRKKDKIAILWGKLKSNSHPSLYTLSPSSVKDYNEGFYLYRVPFLDEIRKFPSLLSYDDGSEHKLDYDNMKKVTQSIMGYFNLRDGYNPSDFKNPLLQKHYKVLHDYLLQIETTFDENETPNTKKDRMMREDDSLRKLYYIRNKILESEKSEDPIIQRLNKYVKIWNMFYKKFNDDN 5y58 B 2.80 BS01 NUC X 1 K39 R41 K42 T43 S204 V211 K251 L256 N257 R258 S278 R318 Y323 V531 Q535 K38 R40 K41 T42 S187 V194 K234 L239 N240 R241 S261 R290 Y295 V503 Q507 3.6.4.12 Q04437 SSESTTFIVDVSPSMMKNNNVSKSMAYLEYTLLNKSKKSRKTDWISCYLANCPVSENSQEIPNVFQIQSFLAPVTTTATIGFIKRLKQYCDQHSHDSMIQCLLVVSLDIKQQFQARKILKQIVVFTDNLDDLDITDEEIDLLTEELSTRIILIDCGSNWLKLVEAIPNSRIYNMNELLVEITSPATSVVKPVRVFSGELRLGADILSTQTSNPSGSMQDENCLCIKVEAFPATKAVSGLNRKTAVEVEDSQKKERYVGVKSIIEYEIHNEGGSSYIPVTISKDSVTKAYRYGADYVVLPSVLVDQTVYESFPGLDLRGFLNREALPRYFLTSESSFITADTRLGCQSDLMAFSALVDVMLENRKIAVARYVSKKDSEVNMCALCPVLIEHSNINSEKKFVKSLTLCRLPFAEDERVTDFPKLLDRTTTSGVPLKKETDGHQIDELMEQFVDSMDTDELPEIPLGNYYQPIGEVTTDTTLPLPSLNKDQEENKKDPLRIPTVFVYRQQQVLLEWIHQLMINDSREFEIPELPDSLKNKISPYTHKKFDSTKLVEVLGIKKVKRGEQHSR 5y59 B 2.40 BS01 III C 1 I62 Q108 L111 L115 K118 D141 L149 E153 I61 Q107 L110 L114 K117 D140 L146 E150 3.6.4.12 Q04437 SSESTTFIVDVSPSMMKNNNVSKSMAYLEYTLLNKSKKSRKTDWISCYLANCPVSENSQEIPNVFQIQSFLAPVTTTATIGFIKRLKQYCDQHSHDSSNEGLQSMIQCLLVVSLDIKQQFQARKILKQIVVFTDNLDDLDIEEIDLLTEELSTRIILIDCGKSNWLKLVEAIPNSRIYNMNELLVEIT 5y5a A 2.21 BS01 III B 1 L151 I183 V186 M187 V232 S234 R266 L267 F514 K522 E523 F529 D536 L539 L549 L112 I139 V142 M143 V188 S190 R222 L223 F428 K436 E437 F443 D450 L453 L463 Q6CJ80 TDLQETFSGFQKQLQSVDSLMKGAIQMIHSKIMQMLLQSLISDAHRILDLTWKHVHYPIFKYFQNWRNRNVAPNYAGHRQLNSILQKIFPQIHKLYYSTLELIFANYNLTALIPSDTRSKLNISTDASNVLKPEDSFSIDCVMASQRCLLYIGCSQRYKIIMEHLSDRYQQADFQKPLRYLDIASTIVPSVGETFLQRGICYTHTKNFGNAAYQFVRSSLSRLPSDAGIPNFTNLLGDPNGSLFKKLLNSLDDLKVQETIKKRIINMEIMEFYILPLIGSHIFPQTWKNNRHSDRLKHFQTLLFDKIEIRYIKNISMIFQDLILLIGSFHMYQMINGVSSNIRSIQSETKFLEFIFKFFTHLIDKVIMKEFKNCEMFQYLAMARIMMCWIKSHKNVLKFAHRSTSFCQSMVNLTNELLSSHRPTRDYFYEEDIMLKEFGPTKFTLSDFNDEKLLSMDNLPDRLVGKSKNKLTAKEEHSSRVQVLVYSNKKFLEKNCCGFKLDTEKKRYVHTAVK 5y5a A 2.21 BS02 III B 2 M463 K467 K470 L473 H477 R508 K576 F577 K580 M387 K391 K394 L397 H401 R422 K490 F491 K494 Q6CJ80 TDLQETFSGFQKQLQSVDSLMKGAIQMIHSKIMQMLLQSLISDAHRILDLTWKHVHYPIFKYFQNWRNRNVAPNYAGHRQLNSILQKIFPQIHKLYYSTLELIFANYNLTALIPSDTRSKLNISTDASNVLKPEDSFSIDCVMASQRCLLYIGCSQRYKIIMEHLSDRYQQADFQKPLRYLDIASTIVPSVGETFLQRGICYTHTKNFGNAAYQFVRSSLSRLPSDAGIPNFTNLLGDPNGSLFKKLLNSLDDLKVQETIKKRIINMEIMEFYILPLIGSHIFPQTWKNNRHSDRLKHFQTLLFDKIEIRYIKNISMIFQDLILLIGSFHMYQMINGVSSNIRSIQSETKFLEFIFKFFTHLIDKVIMKEFKNCEMFQYLAMARIMMCWIKSHKNVLKFAHRSTSFCQSMVNLTNELLSSHRPTRDYFYEEDIMLKEFGPTKFTLSDFNDEKLLSMDNLPDRLVGKSKNKLTAKEEHSSRVQVLVYSNKKFLEKNCCGFKLDTEKKRYVHTAVK 5yxc A 1.76 BS02 CIT A 1 Y101 H167 H176 H178 Y200 M213 H216 Y72 H138 H147 H149 Y171 M184 H187 P76344 GKPLTEVEQKAANGVFDDANVQNRTLSDWDGVWQSVYPLLQSGKLDPVFQKKADADKTKTFAEIKDYYHKGYATDIEMIGIEDGIVEFHRNNETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPKYIQFSDHIIAPRKSSHFHIFMGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH 6amg A 1.45 BS01 HEM A 1 S63 F76 H80 V82 I104 V105 K106 A131 A132 M133 F149 F150 G151 Q163 T167 C168 C171 H172 V181 F182 F185 Y186 S27 F40 H44 V46 I68 V69 K70 A95 A96 M97 F113 F114 G115 Q127 T131 C132 C135 H136 V145 F146 F149 Y150 F9ZFJ0 LNYGSFTKEHVLLTPKGYREWVFIGASVTPNELNDDKAAFPEFHNVYIDPTSWGHWKKTGEFRDGTVIVKELAGVGSKASPSGNGYFPGEFNGIAAMVKDSKRYPERPGNWAFFGFESYEAKQGIIQTDETCAACHKEHAAHDMVFTQFYPVLRAGKP 6amg A 1.45 BS02 HEM B 1 S116 P117 S118 F123 S80 P81 S82 F87 F9ZFJ0 LNYGSFTKEHVLLTPKGYREWVFIGASVTPNELNDDKAAFPEFHNVYIDPTSWGHWKKTGEFRDGTVIVKELAGVGSKASPSGNGYFPGEFNGIAAMVKDSKRYPERPGNWAFFGFESYEAKQGIIQTDETCAACHKEHAAHDMVFTQFYPVLRAGKP 6ap4 C 2.95 BS01 MG C 1 L187 Q218 L190 Q221 V5V7W3 HHHMRLKIAKESLLNVLSHVVGAVERRHTLNILSNVKIQTNAQALTITGSDLEVELVASTALSEGACLEAGETTVPARKLMEICKSLPTAALIDLQITEDQRCILKSGNSRFVLGTLPAEDYPLLTTENSQGTQVQVTQRELKRLFEKTAFAMAVQDVRFYLTGTLLEIDENQLRAVTTDGHRLALCEILASSTSSQLVQAIVPRKAVGELQRLLSIEDEQLTLLIGRELLNVTINDKEQGDITVRFTTKLIDGKFPDYRRVIPRGGDKHVLIGHDVFKQSLQRVAILSNEKLRGVFLNFNQDSLQLRANNPEQDEAIEDLAIQYQSAPLEMSFNAQYLLDVLGVLDGDDVNMSMTEANQSVLVQDPAHPDQTYVVMPM 6apl A 2.35 BS01 C5P A 1 N156 G157 L178 N179 G180 S304 T305 G306 G324 F325 I326 D335 H336 N86 G87 L108 N109 G110 S228 T229 G230 G248 F249 I250 D259 H260 2.4.99.- Q9UJ37 CRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLILYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPANHDLSLEAALWRDLHKAGILQLYQR 6apl B 2.35 BS01 C5P B 1 N156 G157 L178 N179 G180 S304 G306 F325 I326 D335 H336 N87 G88 L109 N110 G111 S233 G235 F254 I255 D264 H265 2.4.99.- Q9UJ37 CRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPYANHDLSLEAALWRDLHKAGILQLYQR 6apl C 2.35 BS01 C5P C 1 G155 N156 G157 L178 N179 G180 S304 G306 F325 I326 D335 H336 L345 G87 N88 G89 L110 N111 G112 S236 G238 F257 I258 D267 H268 L277 2.4.99.- Q9UJ37 CRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR 6avj A 1.90 BS01 FES A 1 C60 V61 C62 S65 C71 D72 S74 C75 P84 C25 V26 C27 S30 C36 D37 S39 C40 P49 P0C7P0 PARSVVALKTPIKVELVAGKTYRWCVCGRSKKQPFCDGSCFFQRTGLSPLKFKAQETRMVALCTCKATQRPPYCDGTCRSERVQKAEVGSPL 6avj A 1.90 BS02 FES A 2 P46 C98 T99 C100 T103 C109 D110 G111 T112 C113 P11 C63 T64 C65 T68 C74 D75 G76 T77 C78 P0C7P0 PARSVVALKTPIKVELVAGKTYRWCVCGRSKKQPFCDGSCFFQRTGLSPLKFKAQETRMVALCTCKATQRPPYCDGTCRSERVQKAEVGSPL 6avj B 1.90 BS02 FES B 2 P46 C98 T99 C100 K101 T103 C109 D110 T112 C113 P11 C63 T64 C65 K66 T68 C74 D75 T77 C78 P0C7P0 PARSVVALKTPIKVELVAGKTYRWCVCGRSKKQPFCDGSCFFQRTGLSPLKFKAQETRMVALCTCKATQRPPYCDGTCRSERVQKAEVGSPL 6ayh A 2.05 BS01 C3G A 1 D68 R71 A72 H75 F76 E99 Q103 V107 K127 L161 L162 T165 Y166 D63 R66 A67 H70 F71 E94 Q98 V102 K122 L156 L157 T160 Y161 A0A1S0ZXA5 NKLTEPLPTRMRILRAARQCFAENGFHSTSMKTICKASDMSPGTLYHHFPSKEALIEAIILEDQERALTHFREPLEGVGLVDYLVESTIAVTREDYAQRALVVEIMAEGMRNPQVAEMLTNKYHTIIASLVARFNDAQAKGEIGADVDKEMAARLLLATTYGVLSDSSSAENARHVSFATTLRTMLTGLLKC 6ayi A 2.09 BS01 C3G A 1 D66 R69 A70 R73 F74 M87 S90 E97 Q101 V105 K125 I129 L160 T163 Y164 D56 R59 A60 R63 F64 M77 S80 E87 Q91 V95 K115 I119 L150 T153 Y154 P0ACT8 PTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLLDLTYGVLADIEAEDLAREASFAQGLRAMIGGIL 6ayi B 2.09 BS01 C3G B 1 R69 A70 R73 F74 M87 I91 L94 E97 V105 K125 I129 L160 T163 Y164 R16 A17 R20 F21 M34 I38 L41 E44 V52 K72 I76 L107 T110 Y111 P0ACT8 SKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLLDLTYGVLADIEAEDLAREASFAQGLRAMIGGILT 6ayi C 2.09 BS01 C3G C 1 R69 A70 R73 F74 M87 E97 Q101 V105 K125 I129 T163 Y164 R59 A60 R63 F64 M77 E87 Q91 V95 K115 I119 T153 Y154 P0ACT8 PTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLLDLTYGVLADIEAEDLAREASFAQGLRAMIGGIL 6b3r A 3.80 BS01 III B 1 Y1359 A2527 K2528 F2531 W2542 Y706 A1483 K1484 F1487 W1498 E2JF22 LVTGIYVKYWIYVCAGMFIVVSFAVYKIVYMFLFLLCLTLFQVYYTLWRKLLRVFWWLVVAYTMLVLIAVYTFQFQDFPTYWRNLTGFTDEQLGDLGLEQFSVSELFSSILIPGFFLLACILQLHYFHRPFMQLTDLRLLDLAASFSAVLTRIQVFVRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCIIIVCKMLYQLKIVNPHNCTEPFPQPLEINQSLLYRGPVDPANWFGVRKGYPNLGYIQNHLQILLLLVFEAVVYRRQEHYRRQHQQAPLPAQAVCADGTRQRLDQDLLSCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFMVILHGCWLVAILTRRRREAIARLWPNYCLFLTLFLLYQYLLCLGMPPALCIDYPWRWSKAIPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGINTDHLEPLRGEPNPIPNFIHCRSYLDMLKVAVFRYLFWLVLVVVFVAGATRISIFGLGYLLACFYLLLFGTTLLQKDTRAQLVLWDCLILYNVTVIISKNMLSLLSCVFVEQMQSNFCWVIQLFSLVCTVKGYYDPKEMMTRDRDCLLPVEEAGIIWDSICFFFLLLQRRIFLSHYFLHVSADLKATALQASRGFALYNAANLKSINFHRQIEEKSLAQLKRQMKRIRAKQEKYRQSQASHMMQRVLSTMQFLWVLGQATVDGLTRWLRAFTKHHRTMSDVLCAERYLLTQELLRVGEVRRGVLDQLYVGEDEATLSGPVETRDGPHIPELEEAERFEAQQGRTLRLLRAGYQCVAAHSELLCYFIIILNHMVTASAASLVLPVLVFLWAMLTIPRPSKRFWMTAIVFTEVMVVTKYLFQFGFFPWNSYVVLRRYENKPYFPPRILGLEKTDSYIKYDLVQLMALFFHRSQLLCYGLWDQSFYQPLQRFFHDILHTKYRAATDVYALMFLADIVDIIIIIFGFWAQVPQAFLFMLLVQFGTMVIDRALYLRKTVLGKLAFQVVLVVAIHIWMFFILQNAVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLIRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTPQAYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKQELYNGTADITLRFTWNFQRDLAKGGTVEYTNEKHTLELAPNSTARRQLAQLLEGRPDQSVVIPHLFPKYIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGSDFLEWWVIELQDCKADCNLLPMVIFSDKVSPPGYGIVGLYVSIVLVVGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTRER 6b3r C 3.80 BS02 III F 1 R2169 P2498 R1143 P1454 E2JF22 LVTGIYVKYWIYVCAGMFIVVSFAVYKIVYMFLFLLCLTLFQVYYTLWRKLLRVFWWLVVAYTMLVLIAVYTFQFQDFPTYWRNLTGFTDEQLGDLGLEQFSVSELFSSILIPGFFLLACILQLHYFHRPFMQLTDLRLLDLAASFSAVLTRIQVFVRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCIIIVCKMLYQLKIVNPHNCTEPFPQPLEINQSLLYRGPVDPANWFGVRKGYPNLGYIQNHLQILLLLVFEAVVYRRQEHYRRQHQQAPLPAQAVCADGTRQRLDQDLLSCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFMVILHGCWLVAILTRRRREAIARLWPNYCLFLTLFLLYQYLLCLGMPPALCIDYPWRWSKAIPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGINTDHLEPLRGEPNPIPNFIHCRSYLDMLKVAVFRYLFWLVLVVVFVAGATRISIFGLGYLLACFYLLLFGTTLLQKDTRAQLVLWDCLILYNVTVIISKNMLSLLSCVFVEQMQSNFCWVIQLFSLVCTVKGYYDPKEMMTRDRDCLLPVEEAGIIWDSICFFFLLLQRRIFLSHYFLHVSADLKATALQASRGFALYNAANLKSINFHRQIEEKSLAQLKRQMKRIRAKQEKYRQSQASHMMQRVLSTMQFLWVLGQATVDGLTRWLRAFTKHHRTMSDVLCAERYLLTQELLRVGEVRRGVLDQLYVGEDEATLSGPVETRDGPHIPELEEAERFEAQQGRTLRLLRAGYQCVAAHSELLCYFIIILNHMVTASAASLVLPVLVFLWAMLTIPRPSKRFWMTAIVFTEVMVVTKYLFQFGFFPWNSYVVLRRYENKPYFPPRILGLEKTDSYIKYDLVQLMALFFHRSQLLCYGLWDQSFYQPLQRFFHDILHTKYRAATDVYALMFLADIVDIIIIIFGFWAQVPQAFLFMLLVQFGTMVIDRALYLRKTVLGKLAFQVVLVVAIHIWMFFILQNAVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLIRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTPQAYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKQELYNGTADITLRFTWNFQRDLAKGGTVEYTNEKHTLELAPNSTARRQLAQLLEGRPDQSVVIPHLFPKYIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGSDFLEWWVIELQDCKADCNLLPMVIFSDKVSPPGYGIVGLYVSIVLVVGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTRER 6b3r E 3.80 BS01 III B 1 Q2177 P2498 Q1151 P1454 E2JF22 LVTGIYVKYWIYVCAGMFIVVSFAVYKIVYMFLFLLCLTLFQVYYTLWRKLLRVFWWLVVAYTMLVLIAVYTFQFQDFPTYWRNLTGFTDEQLGDLGLEQFSVSELFSSILIPGFFLLACILQLHYFHRPFMQLTDLRLLDLAASFSAVLTRIQVFVRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCIIIVCKMLYQLKIVNPHNCTEPFPQPLEINQSLLYRGPVDPANWFGVRKGYPNLGYIQNHLQILLLLVFEAVVYRRQEHYRRQHQQAPLPAQAVCADGTRQRLDQDLLSCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFMVILHGCWLVAILTRRRREAIARLWPNYCLFLTLFLLYQYLLCLGMPPALCIDYPWRWSKAIPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGINTDHLEPLRGEPNPIPNFIHCRSYLDMLKVAVFRYLFWLVLVVVFVAGATRISIFGLGYLLACFYLLLFGTTLLQKDTRAQLVLWDCLILYNVTVIISKNMLSLLSCVFVEQMQSNFCWVIQLFSLVCTVKGYYDPKEMMTRDRDCLLPVEEAGIIWDSICFFFLLLQRRIFLSHYFLHVSADLKATALQASRGFALYNAANLKSINFHRQIEEKSLAQLKRQMKRIRAKQEKYRQSQASHMMQRVLSTMQFLWVLGQATVDGLTRWLRAFTKHHRTMSDVLCAERYLLTQELLRVGEVRRGVLDQLYVGEDEATLSGPVETRDGPHIPELEEAERFEAQQGRTLRLLRAGYQCVAAHSELLCYFIIILNHMVTASAASLVLPVLVFLWAMLTIPRPSKRFWMTAIVFTEVMVVTKYLFQFGFFPWNSYVVLRRYENKPYFPPRILGLEKTDSYIKYDLVQLMALFFHRSQLLCYGLWDQSFYQPLQRFFHDILHTKYRAATDVYALMFLADIVDIIIIIFGFWAQVPQAFLFMLLVQFGTMVIDRALYLRKTVLGKLAFQVVLVVAIHIWMFFILQNAVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLIRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTPQAYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKQELYNGTADITLRFTWNFQRDLAKGGTVEYTNEKHTLELAPNSTARRQLAQLLEGRPDQSVVIPHLFPKYIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGSDFLEWWVIELQDCKADCNLLPMVIFSDKVSPPGYGIVGLYVSIVLVVGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTRER 6b9r A 1.80 BS01 FE A 1 N146 H149 Q153 H190 N138 H141 Q145 H182 29217579 SDAARAARAAALLRAAANDLKRNDRAAEADLGLPPGSFGDYVSGRLPITWDLISRAAQAWPLNERDLLPIHNDTPQGLRMMRVKESEASSRIIERGGGPYYEYRDTAMSRQASYRPEWISMLRVVEDDDPDNPLVEWNKGHLLYQFTYFVGPVNYYFRSGGRSHCVPMNTGDSVWGLPFAPHSFTARSADEPAYILALTYGGELTGDAQRELATFGRAVTSSLALTPGDHGAMLRSVMAARLTTVTELADRSGLKTDRVAALCRTPARAEWPELSALAEALGVSVRELLVPHTTTEADVRIQPGRTASRWSYPGPDAPAYRFTQLAGDPLHPHTTSLAVDVLTARPDAPLPPTYQHQYLYVLGEQPVSVRWRYNGEQYDGRLEPGDSAYVIPGIEFSLSAEKPTELLMLRIGGSATPDVRFALGAMPDGAIGRYIAEDRLWY 6b9r A 1.80 BS02 2HE A 1 R103 Y109 Y111 I127 N146 H149 Q153 H190 F192 R95 Y101 Y103 I119 N138 H141 Q145 H182 F184 29217579 SDAARAARAAALLRAAANDLKRNDRAAEADLGLPPGSFGDYVSGRLPITWDLISRAAQAWPLNERDLLPIHNDTPQGLRMMRVKESEASSRIIERGGGPYYEYRDTAMSRQASYRPEWISMLRVVEDDDPDNPLVEWNKGHLLYQFTYFVGPVNYYFRSGGRSHCVPMNTGDSVWGLPFAPHSFTARSADEPAYILALTYGGELTGDAQRELATFGRAVTSSLALTPGDHGAMLRSVMAARLTTVTELADRSGLKTDRVAALCRTPARAEWPELSALAEALGVSVRELLVPHTTTEADVRIQPGRTASRWSYPGPDAPAYRFTQLAGDPLHPHTTSLAVDVLTARPDAPLPPTYQHQYLYVLGEQPVSVRWRYNGEQYDGRLEPGDSAYVIPGIEFSLSAEKPTELLMLRIGGSATPDVRFALGAMPDGAIGRYIAEDRLWY 6b9r A 1.80 BS03 2HE D 1 K29 W449 K21 W441 29217579 SDAARAARAAALLRAAANDLKRNDRAAEADLGLPPGSFGDYVSGRLPITWDLISRAAQAWPLNERDLLPIHNDTPQGLRMMRVKESEASSRIIERGGGPYYEYRDTAMSRQASYRPEWISMLRVVEDDDPDNPLVEWNKGHLLYQFTYFVGPVNYYFRSGGRSHCVPMNTGDSVWGLPFAPHSFTARSADEPAYILALTYGGELTGDAQRELATFGRAVTSSLALTPGDHGAMLRSVMAARLTTVTELADRSGLKTDRVAALCRTPARAEWPELSALAEALGVSVRELLVPHTTTEADVRIQPGRTASRWSYPGPDAPAYRFTQLAGDPLHPHTTSLAVDVLTARPDAPLPPTYQHQYLYVLGEQPVSVRWRYNGEQYDGRLEPGDSAYVIPGIEFSLSAEKPTELLMLRIGGSATPDVRFALGAMPDGAIGRYIAEDRLWY 6b9r C 1.80 BS02 FE C 1 N146 H149 H190 N142 H145 H186 29217579 DALGSDAARAARAAALLRAAANDLKRNDRAAEADLGLPPGSFGDYVSGRLPITWDLISRAAQAWPLNERDLLPIHNDTPQGLRMMRVKESEASSRIIERGGGPYYEYRDTAMSRQASYRPEWISMLRVVEDDDPDNPLVEWNKGHLLYQFTYFVGPVNYYFRSGGRSHCVPMNTGDSVWGLPFAPHSFTARSADEPAYILALTYGGELTGDAQRELATFGRAVTSSLALTPGDHGAMLRSVMAARLTTVTELADRSGLKTDRVAALCRTPARAEWPELSALAEALGVSVRELLVPHTTTEADVRIQPGRTASRWSYPGPDAPAYRFTQLAGDPLHPHTTSLAVDVLTARPDAPLPPTYQHQYLYVLGEQPVSVRWRYNGEQYDGRLEPGDSAYVIPGIEFSLSAEKPTELLMLRIGGSATPDVRFALGAMPDGAIGRYIAEDRLWY 6b9r C 1.80 BS03 2HE C 1 R103 Y109 Y111 I127 N146 H149 H190 F192 R99 Y105 Y107 I123 N142 H145 H186 F188 29217579 DALGSDAARAARAAALLRAAANDLKRNDRAAEADLGLPPGSFGDYVSGRLPITWDLISRAAQAWPLNERDLLPIHNDTPQGLRMMRVKESEASSRIIERGGGPYYEYRDTAMSRQASYRPEWISMLRVVEDDDPDNPLVEWNKGHLLYQFTYFVGPVNYYFRSGGRSHCVPMNTGDSVWGLPFAPHSFTARSADEPAYILALTYGGELTGDAQRELATFGRAVTSSLALTPGDHGAMLRSVMAARLTTVTELADRSGLKTDRVAALCRTPARAEWPELSALAEALGVSVRELLVPHTTTEADVRIQPGRTASRWSYPGPDAPAYRFTQLAGDPLHPHTTSLAVDVLTARPDAPLPPTYQHQYLYVLGEQPVSVRWRYNGEQYDGRLEPGDSAYVIPGIEFSLSAEKPTELLMLRIGGSATPDVRFALGAMPDGAIGRYIAEDRLWY 6b9s A 2.37 BS01 FE A 1 H148 Q152 H190 H140 Q144 H182 1.13.11.73 A9A1T2 29217579 PDSYLIRSGNNFLGILNDIKRRPEDAANELGVSIEEINSIISGKQKISPSLIEKAVNIWPVNERDFYIVSDDCSSGILIMTSQDSIKSSRIMERAGKPYYEYRDTAMSKTAPFRPEWILELCKVENNDPENPKAQWNNGHFMHQFTYFIGEVNFYYKDPEGKKHVAIMNTGDSMYITPFTPHTFTTRDGASQNGLILALTYGSKLTGDIQQELSSLSLDCGSQYALDFTNHENASLSLLEYYFELSNLTKEKFAKRTNFSMETLADFFTKKKLPTFDELKIIAKALNVNSRDLMPNDLTESKVIVKTHDQCDHWKYPESGNYEFYELASTTALPHSKAFEIDVSSSEDLNLDLKVGLHQYVYNIGDSALTINWNYENKTYQKSLNPGDSAYIKPFVPHNFRGNGKILILRIGGKISGDSQRELSFVGRENTQRAISETMQWF 6b9t A 2.35 BS02 2HE A 1 R102 Y108 Y110 I126 N145 H148 Q152 H190 F192 R93 Y99 Y101 I117 N136 H139 Q143 H181 F183 1.13.11.73 A9A1T2 29217579 DSYLIRSGNNFLGILNDIKRRPEDAANELGVSIEEINSIISGKQKISPSLIEKAVNIWPVNERDFYIVSDDCSSGILIMTSQDSIKSSRIMERAGKPYYEYRDTAMSKTAPFRPEWILELCKVENNDPENPKAQWNNGHFMHQFTYFIGEVNFYYKDPEGKKHVAIMNTGDSMYITPFTPHTFTTRDGASQNGLILALTYGSKLTGDIQQELSSLSLDCGSQYALDFTNHENASLSLLEYYFELSNLTKEKFAKRTNFSMETLADFFTKKKLPTFDELKIIAKALNVNSRDLMPNDLTESKVIVKTHDQCDHWKYPESGNYEFYELASTTALPHSKAFEIDVSSSEDLNLDLKVGLHQYVYNIGDSALTINWNYENKTYQKSLNPGDSAYIKPFVPHNFRGNGKILILRIGGKISGDSQRELSFVGRENTQRAISETMQWFDPKGSN 6b9t A 2.35 BS03 2HE B 1 K28 W449 K19 W440 1.13.11.73 A9A1T2 29217579 DSYLIRSGNNFLGILNDIKRRPEDAANELGVSIEEINSIISGKQKISPSLIEKAVNIWPVNERDFYIVSDDCSSGILIMTSQDSIKSSRIMERAGKPYYEYRDTAMSKTAPFRPEWILELCKVENNDPENPKAQWNNGHFMHQFTYFIGEVNFYYKDPEGKKHVAIMNTGDSMYITPFTPHTFTTRDGASQNGLILALTYGSKLTGDIQQELSSLSLDCGSQYALDFTNHENASLSLLEYYFELSNLTKEKFAKRTNFSMETLADFFTKKKLPTFDELKIIAKALNVNSRDLMPNDLTESKVIVKTHDQCDHWKYPESGNYEFYELASTTALPHSKAFEIDVSSSEDLNLDLKVGLHQYVYNIGDSALTINWNYENKTYQKSLNPGDSAYIKPFVPHNFRGNGKILILRIGGKISGDSQRELSFVGRENTQRAISETMQWFDPKGSN 6b9t D 2.35 BS02 FE D 1 N145 H148 Q152 H190 N142 H145 Q149 H187 1.13.11.73 A9A1T2 29217579 KIDFKPDSYLIRSGNNFLGILNDIKRRPEDAANELGVSIEEINSIISGKQKISPSLIEKAVNIWPVNERDFYIVSDDCSSGILIMTSQDSIKSSRIMERAGKPYYEYRDTAMSKTAPFRPEWILELCKVENNDPENPKAQWNNGHFMHQFTYFIGEVNFYYKDPEGKKHVAIMNTGDSMYITPFTPHTFTTRDGASQNGLILALTYGSKLTGDIQQELSSLSLDCGSQYALDFTNHENASLSLLEYYFELSNLTKEKFAKRTNFSMETLADFFTKKKLPTFDELKIIAKALNVNSRDLMPNDLTESKVIVKTHDQCDHWKYPESGNYEFYELASTTALPHSKAFEIDVSSSEDLNLDLKVGLHQYVYNIGDSALTINWNYENKTYQKSLNPGDSAYIKPFVPHNFRGNGKILILRIGGKISGDSQRELSFVGRENTQRAISETMQWFDPKGSN 6b9t F 2.35 BS03 2HE F 1 R102 Y110 I126 N145 H148 Q152 H190 F192 R93 Y101 I117 N136 H139 Q143 H181 F183 1.13.11.73 A9A1T2 29217579 DSYLIRSGNNFLGILNDIKRRPEDAANELGVSIEEINSIISGKQKISPSLIEKAVNIWPVNERDFYIVSDDCSSGILIMTSQDSIKSSRIMERAGKPYYEYRDTAMSKTAPFRPEWILELCKVENNDPENPKAQWNNGHFMHQFTYFIGEVNFYYKDPEGKKHVAIMNTGDSMYITPFTPHTFTTRDGASQNGLILALTYGSKLTGDIQQELSSLSLDCGSQYALDFTNHENASLSLLEYYFELSNLTKEKFAKRTNFSMETLADFFTKKKLPTFDELKIIAKALNVNSRDLMPNDLTESKVIVKTHDQCDHWKYPESGNYEFYELASTTALPHSKAFEIDVSSSEDLNLDLKVGLHQYVYNIGDSALTINWNYENKTYQKSLNPGDSAYIKPFVPHNFRGNGKILILRIGGKISGDSQRELSFVGRENTQRAISETMQWFDPKGSN 6blj A 2.10 BS01 AMP A 1 R306 E308 F320 R321 V322 F325 L399 V400 S401 T436 A439 R442 R309 E311 F323 R324 V325 F328 L402 V403 S404 T432 A435 R438 HHHMLDINLFREYKGGNPEIIRESQRRRFADVTLVDKVIELDEVWRATIGKLNHIKSFTGIISKEVGNRMKNKVPLGDDLELPKEVTDDVYALFTKEALEQGSLAKLNTNQLKKLSTYITEVHIKNSEEEVKQKEKERDDVLLQIGNIVHETVVVSDNEDNNGIVRMVGNPRPKVDPETGYKCLKHIDIMRKLGGLATEEGTQVGGGRGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTVTGEGEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVGAHGKDTLGIFRVHQFEKIEQFVVTSPKDNKSWEMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNAAAKKFDLEAWFPGADEGNEYRELVSCSNCTDYQTRRLEVKYGEVEFCHMLNSTLTATSRTLCCIVENYQTPEGVNVPEVLQPYMGGTKFIKFKN 6blj B 2.10 BS01 AMP B 1 R306 E308 F320 R321 V322 F325 E398 L399 V400 S401 T436 A439 R442 R264 E266 F278 R279 V280 F283 E356 L357 V358 S359 T394 A397 R400 HHHMLDINLFREYKGGNPEIIRESQRRRFADVTLVDKVIELDEVWRATIGKLNHIKSFTGIISKEQLKKLSTYITEVHIKNSEEEVKQKEKERDDVLLQIGNIVHETVVVSDNEDNNGIVRMVGNPRPKVDPETGYKCLKHIDIMRKLGGLATEEGTQVGGGRGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTVTGEGEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVGAHGKDTLGIFRVHQFEKIEQFVVTSPKDNKSWEMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNAAAKKFDLEAWFPGADEGNEYRELVSCSNCTDYQTRRLEVKYGKSKKQGSEVEFCHMLNSTLTATSRTLCCIVENYQTPEGVNVPEVLQPYMGGTKFIKFKN 6bmb A 2.08 BS01 SKM A 1 I328 S336 S338 S379 K385 N406 D423 Y550 F575 Q578 Q582 I239 S247 S249 S290 K296 N317 D334 Y436 F461 Q464 Q468 4.2.1.10,1.1.1.25 Q9SQT8 VKNPSLICAPVMADSIDKMVIETSKAHELGADLVEIRLDWLKDFNPLEDLKTIIKKSPLPTLFTYRPKWEGGQYEGDENERRDVLRLAMELGADYIDVELQVASEFIKSIDGKKPGKFKVIVSSHNYQNTPSVEDLDGLVARIQQTGADIVKIATTAVDIADVARMFHITSKAQVPTIGLVMGERGLMSRILCSKFGGYLTFGTLDSSKVSAPGQPTIKDLLDLYNFRRIGPDTKVYGIIGKPVSHSKSPIVHNQAFKSVDFNGVYVHLLVDNLVSFLQAYSSSDFAGFSCGIPHKEAALQCCDEVDPLAKSIGAVNTILRRKSDGKLLGYNTDCIGSISAIEDGLTVVVIGAGGAGKALAYGAKEKGAKVVIANRTYERELAEAIGALSLTDLDNYEDGMVLANTTSMGMQPNVEETPISKDALKHYALVFDAVYTPRITRLLREAEESGAITVSGSEMFVRQAYEQFEIFTGLPAPKELYWQIMSKYGSRENLYFQ 6bme A 1.90 BS01 HEM A 1 F64 F65 T72 A75 K76 R79 F80 Y91 H100 H102 L103 L109 F114 V117 L142 V145 F149 F33 F34 T41 A44 K45 R48 F49 Y60 H69 H71 L72 L78 F83 V86 L111 V114 F118 R9RY64 STLHAKLGGAAAVAATVDVFYKKLMNDPDLEPFFRGVDMVTLIAKQNRFLAYAFGATTHYHGKDIVMGHAHLIINRGLNLTHFDKVAGHFVDSLKEMGVGQELIDEAAGVLIGVRPLFDPERYKGKV 6bme B 1.90 BS01 HEM B 1 F64 F65 T72 K76 R79 F80 Y91 H100 L103 L109 F114 V117 L142 V145 F149 F32 F33 T40 K44 R47 F48 Y59 H68 L71 L77 F82 V85 L110 V113 F117 R9RY64 TLHAKLGGAAAVAATVDVFYKKLMNDPDLEPFFRGVDMVTLIAKQNRFLAYAFGATTHYHGKDIVMGHAHLIINRGLNLTHFDKVAGHFVDSLKEMGVGQELIDEAAGVLIGVRPLFDPERYKGK 6bn6 A 2.40 BS01 XGH A 1 C285 Q286 W317 C320 H323 L324 A327 M358 V361 R364 M365 R367 A368 V376 F378 F388 I397 I400 F401 H479 L483 C21 Q22 W53 C56 H59 L60 A63 M94 V97 R100 M101 R103 A104 V112 F114 F124 I133 I136 F137 H215 L219 P51449 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPI 6bn6 B 2.40 BS01 XGH B 1 Q286 L287 W317 C320 H323 L324 M358 V361 R364 M365 R367 V376 F388 L396 I397 I400 F401 H479 L483 Q23 L24 W54 C57 H60 L61 M95 V98 R101 M102 R104 V113 F125 L133 I134 I137 F138 H216 L220 P51449 MASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIF 6bnh A BS01 III B 1 Y12 R16 S19 L20 I22 N23 L30 G31 V34 P49 D50 E51 I52 E53 I54 F56 E57 Y12 R16 S19 L20 I22 N23 L30 G31 V34 P49 D50 E51 I52 E53 I54 F56 E57 O60885 29176719 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA 6bns A 2.56 BS01 XGH A 1 L206 L209 V211 P227 I236 L239 L240 M243 S247 Y306 H407 L411 F420 M425 L51 L54 V56 P72 I81 L84 L85 M88 S92 Y151 H246 L250 F259 M264 2.3.1.48 Q15788 GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITSLTERHKILHRLLQE 6bns B 2.56 BS01 XGH B 1 L206 L209 K210 V211 P227 I236 L239 L240 M243 S247 F288 W299 Y306 M323 H407 F420 M425 L47 L50 K51 V52 P68 I77 L80 L81 M84 S88 F129 W140 Y147 M159 H243 F256 M261 2.3.1.48 Q15788 GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITSLTERHKILHRLLQE 6bqr A 3.20 BS01 Y01 A 1 W680 I690 V694 F698 F783 V787 V788 N913 W539 I549 V553 F557 F588 V592 V593 N703 Q8TD43 29217581 YGELDFTGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLAPGSGGARQGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASHSVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCRRPRHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREY 6bqr A 3.20 BS02 Y01 A 2 L934 L937 G938 L941 P960 L963 F967 Y968 Y971 L724 L727 G728 L731 P750 L753 F757 Y758 Y761 Q8TD43 29217581 YGELDFTGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLAPGSGGARQGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASHSVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCRRPRHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREY 6bqr A 3.20 BS03 Y01 A 3 W864 V904 L907 I920 V923 S924 M927 F931 W654 V694 L697 I710 V713 S714 M717 F721 Q8TD43 29217581 YGELDFTGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLAPGSGGARQGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASHSVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCRRPRHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREY 6bqr A 3.20 BS04 Y01 B 1 W1018 V1021 L1022 V1025 W808 V811 L812 V815 Q8TD43 29217581 YGELDFTGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLAPGSGGARQGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASHSVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCRRPRHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREY 6bqr A 3.20 BS05 Y01 B 2 F936 W940 V1025 I1026 L1029 V1030 F726 W730 V815 I816 L819 V820 Q8TD43 29217581 YGELDFTGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLAPGSGGARQGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASHSVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCRRPRHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREY 6bqv A 3.10 BS01 CA A 1 E828 Q831 Y859 N865 D868 E603 Q606 Y628 N634 D637 Q8TD43 29217581 TGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWVQFPLDYNYSAFFLVDDLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCREHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLKVL 6bqv A 3.10 BS02 Y01 A 1 W680 I690 V694 F783 V787 V788 L791 L795 N913 W510 I520 V524 F558 V562 V563 L566 L570 N682 Q8TD43 29217581 TGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWVQFPLDYNYSAFFLVDDLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCREHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLKVL 6bqv A 3.10 BS03 Y01 A 2 L934 L937 G938 L941 P960 L963 R964 F967 Y968 Y971 L703 L706 G707 L710 P729 L732 R733 F736 Y737 Y740 Q8TD43 29217581 TGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWVQFPLDYNYSAFFLVDDLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCREHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLKVL 6bqv A 3.10 BS04 Y01 A 3 L907 H908 I920 V923 S924 M927 L676 H677 I689 V692 S693 M696 Q8TD43 29217581 TGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWVQFPLDYNYSAFFLVDDLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCREHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLKVL 6bqv A 3.10 BS05 Y01 B 1 W1018 V1021 V1025 W787 V790 V794 Q8TD43 29217581 TGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWVQFPLDYNYSAFFLVDDLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCREHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLKVL 6bqv A 3.10 BS06 Y01 B 2 V1025 I1026 L1029 V1030 V794 I795 L798 V799 Q8TD43 29217581 TGAGRHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWVQFPLDYNYSAFFLVDDLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTLGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASVGHVLRMLLGPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGSGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQLCREHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLKVL 6btw A 1.90 BS01 E8D A 1 I43 I51 V69 K71 E83 Y87 P111 M131 D132 R133 F134 V196 D197 I24 I27 V45 K47 E59 Y63 P87 M107 D108 R109 F110 V172 D173 2.7.11.1 Q99986 AEQFAVGEIITDMAAAAWKVGLPIGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6btw B 1.90 BS01 E8D B 1 I43 I51 V69 K71 P111 M131 D132 R133 F134 V196 D197 I21 I23 V36 K38 P75 M91 D92 R93 F94 V156 D157 2.7.11.1 Q99986 FAVGEIITDMAAAAWKVGLPICIYLADMNSSDAPCVVKVEPGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6bu6 A 1.80 BS01 E8V A 1 I43 G44 F48 I51 V69 K71 E83 D132 R133 F134 L184 V196 I24 G25 F29 I32 V50 K52 E64 D113 R114 F115 L165 V177 2.7.11.1 Q99986 AEQFAVGEIITDMAAAAWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6bu6 B 1.80 BS01 E8V B 1 G44 Q45 F48 I51 V69 K71 E83 M131 D132 R133 F134 D137 K140 L184 G22 Q23 F26 I29 V42 K44 E53 M97 D98 R99 F100 D103 K106 L150 2.7.11.1 Q99986 FAVGEIITDMAAAAWKVGLPIGQGGFGCIYLADMNGSDAPCVVKVEPSPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6bu6 D 1.80 BS01 E8V D 1 I43 G44 F48 I51 V69 K71 M131 D132 R133 F134 G135 D137 K140 L184 V196 D197 I22 G23 F25 I28 V46 K48 M108 D109 R110 F111 G112 D114 K117 L161 V173 D174 2.7.11.1 Q99986 QFAVGEIITDMAAAAWKVGLPIGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6buz A 3.92 BS01 NUC I 1 Q45 R63 R72 N85 W86 Q87 A88 R118 V119 T120 F122 Q1 R19 R28 N41 W42 Q43 A44 R74 V75 T76 F78 P49450 QGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGL 6buz A 3.92 BS02 NUC J 1 Q45 R63 K64 L65 P66 R69 N85 Q1 R19 K20 L21 P22 R25 N41 P49450 QGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGL 6buz B 3.92 BS01 NUC I 1 T31 R37 K45 R46 T8 R14 K22 R23 P62805 RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 6buz C 3.92 BS01 NUC I 1 R12 A13 K14 K16 T17 R18 R21 G29 R30 R33 R78 R1 A2 K3 K5 T6 R7 R10 G18 R19 R22 R67 P04908 RAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLP 6buz E 3.92 BS01 NUC I 1 Q45 W47 K49 R63 K64 L65 P66 R69 N85 Q1 W3 K5 R19 K20 L21 P22 R25 N41 P49450 QGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGL 6buz E 3.92 BS02 NUC J 1 R63 R72 N85 W86 Q87 R118 V119 T120 R19 R28 N41 W42 Q43 R74 V75 T76 P49450 QGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGL 6buz G 3.92 BS02 NUC J 1 R12 A13 K16 R18 R21 G29 R33 R78 R1 A2 K5 R7 R10 G18 R22 R67 P04908 RAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLP 6buz N 3.92 BS01 NUC I 1 M18 K45 R169 R170 M18 K41 R118 R119 Q96H22 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQRQRKESVVQHLIHLCEEKRSDAALLDIIYMQFHQHQKMKQFKNSFKKVTVSFRETAVWIRIAWGTKPNQYKPTYVVYYSQRRNTPLLGQALTIASKH 6en5 A 1.75 BS02 BJ2 A 1 Q259 H331 A332 S333 A334 H361 E362 H365 Y369 E389 K489 F490 H491 T496 Y498 Y501 Q254 H326 A327 S328 A329 H356 E357 H360 Y364 E384 K484 F485 H486 T491 Y493 Y496 3.2.1.-,3.4.15.1 P12821 29206036 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLPCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEG 6eql A 2.38 BS01 UDP A 1 L9 T10 T11 Y15 V82 D102 A103 D104 H212 L214 G215 K218 L9 T10 T11 Y15 V82 D102 A103 D104 H211 L213 G214 K217 2.4.1.186 P46976 MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRRLVVLATPQVSDSMRKVLETVFDEVIMVDVLDSGDSAHLTLMKRPELGVTLTKLHCWSLTQYSKCVFMDADTLVLANIDDLFDREELSAAPDPGWPDCFNSGVFVYQPSVETYNQLLHLASEQGSFDGGDQGILNTFFSSWATTDIRKHLPFIYNLSSISISYLPAFKVFGASAKVVHFLGRVKPWNYTYDPKTKSVPNMTHPEFLILWWNIFTTNVLPLL 6eql A 2.38 BS02 MN A 1 D102 D104 H212 D102 D104 H211 2.4.1.186 P46976 MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRRLVVLATPQVSDSMRKVLETVFDEVIMVDVLDSGDSAHLTLMKRPELGVTLTKLHCWSLTQYSKCVFMDADTLVLANIDDLFDREELSAAPDPGWPDCFNSGVFVYQPSVETYNQLLHLASEQGSFDGGDQGILNTFFSSWATTDIRKHLPFIYNLSSISISYLPAFKVFGASAKVVHFLGRVKPWNYTYDPKTKSVPNMTHPEFLILWWNIFTTNVLPLL 6eql B 2.38 BS02 MN B 1 D102 D104 H212 L214 D100 D102 H195 L197 2.4.1.186 P46976 DQAFVTLTTNDAYAKGALVLGSSLKQHRTTRRLVVLATPQVSDSMRKVLETVFDEVIMVDVLDSGDSAHLTLMKRPELGVTLTKLHCWSLTQYSKCVFMDADTLVLANIDDLFDREELSAAPDPGWPDCFNSGVFVYQPSVETYNQLLHLASEQGSFDGGDQGILNTFFSSWATTDIRKHLPFIYNLSSSAKVVHFLGRVKPWNYTPEFLILWWNIFTTNVLPL 6eqn B 1.96 BS01 PLP B 1 H110 K111 Q138 V260 G262 G263 G264 S265 N266 A381 E383 S412 G413 H99 K100 Q127 V239 G241 G242 G243 S244 N245 A360 E362 S391 G392 4.2.1.20 Q97TX6 RIRIDLPQDEIPAQWYNILPDLPEELPPPQDLKEVLPSKVLELEFAKERYVKIPDEVLERYLQVGRPTPIIRAKRLEEYLGNNIKIYLKMESYTYTGSHKINSALAHVYYAKLDNAKFVTTETGAGQWGSSVALASALFRMKAHIFMVRTSYYAKPYRKYMMQMYGAEVHPSPLTKDSNHPGSLGIAISDAVEYAHKNGGKYVVGSVVNSDIMFKTIAGMEAKKQMELIGEDPDYIIGVVGGGSNYAALAYPFLGDELRSGKVRRKYIASGSSEVPKMTKGVYKYDYPDTAKLLPMLKMYTIGSDFVPPPVYAGGLRYHGVAPTLSLLISKGIVQARDYSQEESFKWAKLFSELEGYIPAPETSHALPILAEIAEEAKKSGERKTVLVSFSGHGLLDLGNYASVLFK 6esf A 3.70 BS01 NUC I 1 K37 R40 Y41 T45 R72 R83 F84 R116 V117 T118 M120 K1 R4 Y5 T9 R36 R47 F48 R80 V81 T82 M84 P84233 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esf A 3.70 BS02 NUC J 1 R40 Y41 R42 P43 G44 V46 A47 R49 R63 K64 L65 P66 R69 R83 R4 Y5 R6 P7 G8 V10 A11 R13 R27 K28 L29 P30 R33 R47 P84233 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esf B 3.70 BS02 NUC J 1 H18 R45 I46 S47 G48 R78 K79 T80 H1 R28 I29 S30 G31 R61 K62 T63 P62799 HRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6esf C 3.70 BS01 NUC I 1 R17 R20 G28 R29 R42 R77 R2 R5 G13 R14 R27 R62 Q6AZJ8 TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPKK 6esf D 3.70 BS02 NUC J 1 K28 R30 K31 I36 Y37 K1 R3 K4 I9 Y10 P02281 KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6esf E 3.70 BS01 NUC I 1 R40 Y41 R42 P43 G44 V46 R49 R63 K64 L65 R69 R83 R4 Y5 R6 P7 G8 V10 R13 R27 K28 L29 R33 R47 P84233 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esf G 3.70 BS01 NUC I 1 R29 E41 R42 V43 G44 A45 K75 T76 R77 K119 R14 E26 R27 V28 G29 A30 K60 T61 R62 K104 Q6AZJ8 TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPKKT 6esg A 5.40 BS01 NUC I 1 R40 Y41 R42 T45 R63 R72 R83 F84 R116 V117 T118 M120 R3 Y4 R5 T8 R26 R35 R46 F47 R79 V80 T81 M83 P84233 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esg B 5.40 BS01 NUC I 1 T30 P32 K44 R45 K77 T7 P9 K21 R22 K54 P62799 DNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6esg B 5.40 BS02 NUC J 1 R35 K44 R45 I46 K79 T80 R12 K21 R22 I23 K56 T57 P62799 DNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6esg C 5.40 BS02 NUC J 1 R29 E41 R42 V43 G44 T76 R77 R14 E26 R27 V28 G29 T61 R62 Q6AZJ8 TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVL 6esg D 5.40 BS02 NUC J 1 I36 Y37 T85 I4 Y5 T53 P02281 SYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6esg E 5.40 BS01 NUC I 1 P43 G44 A47 R49 R63 K64 L65 P66 R69 R83 K115 P2 G3 A6 R8 R22 K23 L24 P25 R28 R42 K74 P84233 RPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE 6esg E 5.40 BS02 NUC J 1 R63 R72 F84 R116 V117 T118 M120 R22 R31 F43 R75 V76 T77 M79 P84233 RPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE 6esg F 5.40 BS01 NUC I 1 R35 R39 K44 R45 I46 S47 G48 R78 K79 T80 R12 R16 K21 R22 I23 S24 G25 R55 K56 T57 P62799 DNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6esg G 5.40 BS01 NUC I 1 R35 R42 V43 G44 T76 R77 R20 R27 V28 G29 T61 R62 Q6AZJ8 TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLP 6esg H 5.40 BS01 NUC I 1 I36 Y37 K40 I4 Y5 K8 P02281 SYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6esh A 5.10 BS01 NUC I 1 K37 R40 Y41 R42 T45 R63 R72 R83 F84 Q85 K115 R116 V117 T118 M120 K1 R4 Y5 R6 T9 R27 R36 R47 F48 Q49 K79 R80 V81 T82 M84 P84233 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esh A 5.10 BS02 NUC J 1 H39 R40 Y41 R42 P43 G44 R49 R63 K64 L65 P66 R69 R83 H3 R4 Y5 R6 P7 G8 R13 R27 K28 L29 P30 R33 R47 P84233 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esh C 5.10 BS01 NUC I 1 R17 G28 R29 R32 R77 R2 G13 R14 R17 R62 Q6AZJ8 TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVL 6esh C 5.10 BS02 NUC J 1 R29 R35 E41 R42 V43 G44 A45 R14 R20 E26 R27 V28 G29 A30 Q6AZJ8 TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVL 6esh D 5.10 BS01 NUC I 1 Y39 R83 S84 Y9 R53 S54 P02281 KESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6esh D 5.10 BS02 NUC J 1 K31 I36 Y37 K1 I6 Y7 P02281 KESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6esh E 5.10 BS01 NUC I 1 R40 Y41 V46 A47 R63 K64 L65 R69 R83 R2 Y3 V8 A9 R25 K26 L27 R31 R45 P84233 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE 6esh E 5.10 BS02 NUC J 1 P43 R63 R72 L82 R83 F84 Q85 R116 V117 T118 P5 R25 R34 L44 R45 F46 Q47 R78 V79 T80 P84233 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE 6esh F 5.10 BS01 NUC I 1 R35 R39 R45 I46 G48 Y51 R78 K79 T80 R14 R18 R24 I25 G27 Y30 R57 K58 T59 P62799 LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6esh G 5.10 BS01 NUC I 1 T16 R29 R42 V43 A45 K75 T76 R77 K119 T1 R14 R27 V28 A30 K60 T61 R62 K104 Q6AZJ8 TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPKK 6esi A 6.30 BS01 NUC I 1 R40 Y41 R42 P43 T45 L48 R52 L61 I62 R63 R83 R116 V117 T118 R4 Y5 R6 P7 T9 L12 R16 L25 I26 R27 R47 R80 V81 T82 P84233 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esi A 6.30 BS02 NUC J 1 H39 Y41 V46 R53 K56 R63 P66 R83 H3 Y5 V10 R17 K20 R27 P30 R47 P84233 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esi B 6.30 BS01 NUC I 1 T30 P32 A33 K77 T6 P8 A9 K53 P62799 NIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 6esi B 6.30 BS02 NUC J 1 R35 R39 R45 I46 G48 Y51 K79 T80 R11 R15 R21 I22 G24 Y27 K55 T56 P62799 NIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 6esi C 6.30 BS01 NUC I 1 R17 S18 G28 R29 R32 R42 R1 S2 G12 R13 R16 R26 Q6AZJ8 RSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIA 6esi C 6.30 BS02 NUC J 1 E41 R42 V43 R77 E25 R26 V27 R61 Q6AZJ8 RSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIA 6esi D 6.30 BS01 NUC I 1 K43 T49 I51 R83 S84 T85 K13 T19 I21 R53 S54 T55 P02281 KESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAR 6esi D 6.30 BS02 NUC J 1 K31 I36 Y37 G50 K1 I6 Y7 G20 P02281 KESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAR 6esi E 6.30 BS01 NUC I 1 R49 Y54 R63 L65 P66 R69 K115 R2 Y7 R16 L18 P19 R22 K68 P84233 LREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esi E 6.30 BS02 NUC J 1 L61 R63 R83 R116 V117 T118 M120 L14 R16 R36 R69 V70 T71 M73 P84233 LREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6esi F 6.30 BS01 NUC I 1 K31 R35 R39 R45 I46 S47 G48 Y51 R78 K79 T80 K12 R16 R20 R26 I27 S28 G29 Y32 R59 K60 T61 P62799 KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6esi F 6.30 BS02 NUC J 1 T30 P32 K44 R45 T80 T11 P13 K25 R26 T61 P62799 KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6esi G 6.30 BS01 NUC I 1 R35 E41 R42 T76 R77 R20 E26 R27 T61 R62 Q6AZJ8 TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLP 6esi G 6.30 BS02 NUC J 1 T16 R17 R29 E41 K74 R77 T1 R2 R14 E26 K59 R62 Q6AZJ8 TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLP 6esi H 6.30 BS01 NUC I 1 R30 Y37 K40 R1 Y8 K11 P02281 RKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6esi H 6.30 BS02 NUC J 1 G50 R83 S84 T85 K122 G21 R54 S55 T56 K93 P02281 RKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6ev3 A 1.30 BS01 4LU A 1 T153 N168 S170 I171 A172 R173 Q190 H191 S223 S224 M225 P226 E233 C316 E322 T323 I327 K391 T150 N165 S167 I168 A169 R170 Q187 H188 S220 S221 M222 P223 E230 C313 E319 T320 I324 K388 4.1.1.102 A2QHE5 QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGRLARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPDGTWTNWSIARAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGSSLELVKCDTNDLYVPATSEIVLEGTLSISETGPEGPFGEMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDETHTMIGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVGDDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPEDLKQKVLDNWTKMGFSHHHH 6ev3 A 1.30 BS03 FZZ A 1 T153 N168 S170 I171 A172 Q190 H191 S223 S224 M225 P226 E233 C316 T323 I327 K391 T395 F437 L439 T150 N165 S167 I168 A169 Q187 H188 S220 S221 M222 P223 E230 C313 T320 I324 K388 T392 F434 L436 4.1.1.102 A2QHE5 QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGRLARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPDGTWTNWSIARAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGSSLELVKCDTNDLYVPATSEIVLEGTLSISETGPEGPFGEMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDETHTMIGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVGDDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPEDLKQKVLDNWTKMGFSHHHH 6ev7 A 1.06 BS02 4LU A 1 T153 N168 S170 I171 A172 R173 Q190 H191 S223 S224 M225 P226 E233 D282 C316 T323 I327 K391 T150 N165 S167 I168 A169 R170 Q187 H188 S220 S221 M222 P223 E230 D279 C313 T320 I324 K388 4.1.1.102 A2QHE5 QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGRLARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPDGTWTNWSIARAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGSSLELVKCDTNDLYVPATSEIVLEGTLSISETGPEGPFGDMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDETHTMIGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVGDDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPEDLKQKVLDNWTKMGFSHHHH 6ev9 A 1.64 BS02 BYN A 1 T153 N168 S170 I171 A172 R173 Q190 H191 S223 S224 M225 P226 E233 T323 I327 K391 T150 N165 S167 I168 A169 R170 Q187 H188 S220 S221 M222 P223 E230 T320 I324 K388 4.1.1.102 A2QHE5 QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGRLARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPDGTWTNWSIARAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGSSLELVKCDTNDLYVPATSEIVLEGTLSISETGPDGPFGEMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDETHTMIGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVGDDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPEDLKQKVLDNWTKMGFS 6eva A 1.64 BS02 4MJ A 1 T153 N168 S170 I171 A172 R173 L185 Q190 H191 S223 S224 M225 P226 E233 M283 C316 T323 I327 K391 F437 L439 T150 N165 S167 I168 A169 R170 L182 Q187 H188 S220 S221 M222 P223 E230 M280 C313 T320 I324 K388 F434 L436 4.1.1.102 A2QHE5 QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGRLARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPDGTWTNWSIARAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGSSLELVKCDTNDLYVPATSEIVLEGTLSISETGPQGPFGEMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDETHTMIGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVGDDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPEDLKQKVLDNWTKMGFSHHHH 6evc A 1.18 BS03 F5C A 1 R173 I187 Q190 Q282 M283 I327 Y394 T395 F437 L439 R170 I184 Q187 Q279 M280 I324 Y391 T392 F434 L436 4.1.1.102 A2QHE5 QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGRLARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPDGTWTNWSIARAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGSSLELVKCDTNDLYVPATSEIVLEGTLSISETGPEGPFGQMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDETHTMIGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVGDDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPEDLKQKVLDNWTKMGFSHHHH 6evd A 1.19 BS02 BYN A 1 T153 N168 S170 I171 A172 A173 Q190 H191 S223 S224 M225 P226 E233 C316 T323 I327 K391 T150 N165 S167 I168 A169 A170 Q187 H188 S220 S221 M222 P223 E230 C313 T320 I324 K388 4.1.1.102 A2QHE5 QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGRLARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPDGTWTNWSIAAAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGSSLELVKCDTNDLYVPATSEIVLEGTLSISETGPEGPFGEMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDETHTMIGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVGDDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPEDLKQKVLDNWTKMGFS 6eve A 2.05 BS01 4LU A 1 T155 N170 S172 I173 A174 A175 Q192 H193 S226 S227 M228 P229 E236 S317 P319 I330 K394 T155 N170 S172 I173 A174 A175 Q192 H193 S226 S227 M228 P229 E236 S314 P316 I327 K391 4.1.1.102 Q03034 MRKLNPALEFRDFIQVLKDEDDLIEITEEIDPNLEVGAIMRKAYESHLPAPLFKNLKGASKDLFSILGCPAGLRSKEKGDHGRIAHHLGLDPKTTIKEIIDYLLECKEKEPLPPITVPVSSAPCKTHILSEEKIHLQSLPTPYLHVSDGGKYLQTYGMWILQTPDKKWTNWSIAAGMVVDDKHITGLVIKPQHIRQIADSWAAIGKANEIPFALCFGVPPAAILVSSMPIPEGVSESDYVGAILGESVPVVKCETNDLMVPATSEMVFEGTLSLTDTHLEGPFGEMHGYVFKSPCPLYTVKAMSYRDNAILPVSNPGLCTDETHTLIGSLVATEAKELAIESGLPILDAFMPYEAQALWLILKVDLKGLQALKTTPEEFCKKVGDIYFRTKVGFIVHEIILVADDIDIFNFKEVIWAYVTRHTPVADQMAFDDVTSFPLAPFVSQSSRSKTMKGGKCVTNCIFRQQYERSFDYITCNFEKGYPKGLVDKVNENWKRYGYK 6eve D 2.05 BS03 MN D 2 W171 V225 S226 M228 E236 W168 V222 S223 M225 E233 4.1.1.102 Q03034 LNPALEFRDFIQVLKDEDDLIEITEEIDPNLEVGAIMRKAYESHLPAPLFKNLKGASKDLFSILGCPAGLRSKEKGDHGRIAHHLGLDPKTTIKEIIDYLLECKEKEPLPPITVPVSSAPCKTHILSEEKIHLQSLPTPYLHVSDGGKYLQTYGMWILQTPDKKWTNWSIAAGMVVDDKHITGLVIKPQHIRQIADSWAAIGKANEIPFALCFGVPPAAILVSSMPIPEGVSESDYVGAILGESVPVVKCETNDLMVPATSEMVFEGTLSLTDTHLEGPFGEMHGYVFKSPCPLYTVKAMSYRDNAILPVSNPGLCTDETHTLIGSLVATEAKELAIESGLPILDAFMPYEAQALWLILKVDLKGLQALKTTPEEFCKKVGDIYFRTKVGFIVHEIILVADDIDIFNFKEVIWAYVTRHTPVADQMAFDDVTSFPLAPFVSQSSRSKTMKGGKCVTNCIFRQQYERSFDYITCNFEKGYPKGLVDKVNENWKRYGYK 6evf A 2.06 BS01 4LU A 1 T155 N170 S172 I173 A174 R175 L187 Q192 H193 S226 S227 M228 P229 E236 S317 P319 T326 I330 K394 T155 N170 S172 I173 A174 R175 L187 Q192 H193 S226 S227 M228 P229 E236 S317 P319 T326 I330 K394 4.1.1.102 Q03034 MRKLNPALEFRDFIQVLKDEDDLIEITEEIDPNLEVGAIMRKAYESHLPAPLFKNLKGASKDLFSILGCPAGLRSKEKGDHGRIAHHLGLDPKTTIKEIIDYLLECKEKEPLPPITVPVSSAPCKTHILSEEKIHLQSLPTPYLHVSDGGKYLQTYGMWILQTPDKKWTNWSIARGMVVDDKHITGLVIKPQHIRQIADSWAAIGKANEIPFALCFGVPPAAILVSSMPIPEGVSESDYVGAILGESVPVVKCETNDLMVPATSEMVFEGTLSLTDTHLEGPFGDMHGYVFKSQGHPCPLYTVKAMSYRDNAILPVSNPGLCTDETHTLIGSLVATEAKELAIESGLPILDAFMPYEAQALWLILKVDLKGLQALKTTPEEFCKKVGDIYFRTKVGFIVHEIILVADDIDIFNFKEVIWAYVTRHTPVADQMAFDDVTSFPLAPFVSQSSRSKTMKGGKCVTNCIFRQQYERSFDYITCNFEKGYPKGLVDKVNENWKRYGYK 6evf B 2.06 BS01 4LU B 1 T155 N170 S172 I173 A174 R175 L187 Q192 H193 S227 M228 P229 E236 D285 S317 P319 T326 I330 K394 T154 N169 S171 I172 A173 R174 L186 Q191 H192 S226 M227 P228 E235 D284 S316 P318 T325 I329 K393 4.1.1.102 Q03034 RKLNPALEFRDFIQVLKDEDDLIEITEEIDPNLEVGAIMRKAYESHLPAPLFKNLKGASKDLFSILGCPAGLRSKEKGDHGRIAHHLGLDPKTTIKEIIDYLLECKEKEPLPPITVPVSSAPCKTHILSEEKIHLQSLPTPYLHVSDGGKYLQTYGMWILQTPDKKWTNWSIARGMVVDDKHITGLVIKPQHIRQIADSWAAIGKANEIPFALCFGVPPAAILVSSMPIPEGVSESDYVGAILGESVPVVKCETNDLMVPATSEMVFEGTLSLTDTHLEGPFGDMHGYVFKSQGHPCPLYTVKAMSYRDNAILPVSNPGLCTDETHTLIGSLVATEAKELAIESGLPILDAFMPYEAQALWLILKVDLKGLQALKTTPEEFCKKVGDIYFRTKVGFIVHEIILVADDIDIFNFKEVIWAYVTRHTPVADQMAFDDVTSFPLAPFVSQSSRSKTMKGGKCVTNCIFRQQYERSFDYITCNFEKGYPKGLVDKVNENWKRYGYK 6eyz A 2.20 BS01 C5W A 1 T750 M752 P758 W760 I777 K779 L784 D787 I825 E826 V827 V828 D832 T833 M900 I910 D911 T588 M590 P596 W598 I615 K617 L622 D625 I663 E664 V665 V666 D670 T671 M738 I748 D749 Q3UDT3 29232121 DRVKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPASLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVDCPIAWANLMLFDYKDQLKTGERCLYMWPSVLLNPAGTVRGNPNTESAAALVIYLPEVAPHPVYFPALEKILELGRHGERRITEEEQLQLREILERGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVN