5bk0 A 3.15 BS01 III E 1 F27D Y32 T91 V92 Y96 F31 Y36 T95 V96 Y100 DIVMTQSPLSLPVSPGEPASISCRSTQSLIFGEHNYLDWYLQKPGQSPQLLIYLASNRASGVPDRFSGSGSGTYFTLKISRVEAEDFGVYYCVQTVQVPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 5bk0 B 3.15 BS01 III E 1 Y32 A33 I50 Y52 T94 L96 I97 Y98 Y32 A33 I50 Y52 T98 L100 I101 Y102 EVQLLESGGGLEQPGGSLRLSCVVSGFTFSNYAFNWVRQAPGKGLEWVAIIYRSGSRMYHADSVKGRFTISRDDSKNTLFLQMNNLRAEDTAVYYCTTLLIYESDVGVDFWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 5bk3 L 2.80 BS01 FUC L 1 N29 R30 T31 W50 S52 S67 N35 R36 T37 W56 S58 S73 DIVMTQSPDSLAVSLGERATINCKSSQSVFFSSNNRTYFAWYQQKPGQPPKVLISWASTRESGVPDRFSGSGSGTDFTLTINSLQAEDVAVYFCQQYYSSPITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 5bk3 B 2.80 BS01 FUC B 1 N29 R30 T31 W50 S52 N35 R36 T37 W56 S58 DIVMTQSPDSLAVSLGERATINCKSSQSVFFSSNNRTYFAWYQQKPGQPPKVLISWASTRESGVPDRFSGSGSGTDFTLTINSLQAEDVAVYFCQQYYSSPITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 5bk3 D 2.80 BS01 FUC D 1 N29 R30 T31 W50 S52 T53 N35 R36 T37 W56 S58 T59 DIVMTQSPDSLAVSLGERATINCKSSQSVFFSSNNRTYFAWYQQKPGQPPKVLISWASTRESGVPDRFSGSGSGTDFTLTINSLQAEDVAVYFCQQYYSSPITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 5bk3 F 2.80 BS01 FUC F 1 T31 W50 S52 T37 W56 S58 DIVMTQSPDSLAVSLGERATINCKSSQSVFFSSNNRTYFAWYQQKPGQPPKVLISWASTRESGVPDRFSGSGSGTDFTLTINSLQAEDVAVYFCQQYYSSPITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 5h7o B 2.80 BS03 7Q7 B 1 V236 C239 L240 L246 A248 D249 K252 L253 N256 M257 V313 A314 A315 N347 N348 K350 A352 I368 V234 C237 L238 L244 A246 D247 K250 L251 N254 M255 V311 A312 A313 N345 N346 K348 A350 I366 Q6B856 29180476 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5h7o D 2.80 BS02 7Q7 D 1 V236 C239 L240 L246 N247 A248 K252 L253 N256 M257 V313 A315 I316 N347 N348 K350 A352 I368 V236 C239 L240 L246 N247 A248 K252 L253 N256 M257 V303 A305 I306 N337 N338 K340 A342 I358 Q6B856 29180476 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5h7o F 2.80 BS01 ACP F 1 K74 I148 Q183 K184 Y185 L186 K198 D200 R202 R222 L240 T241 N242 D318 M320 E331 N333 K74 I126 Q150 K151 Y152 L153 K165 D167 R169 R189 L207 T208 N209 D281 M283 E294 N296 E1BQ43 29180476 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGREGNVWIALISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH 5kdi A 1.45 BS01 6S8 A 1 F311 F312 V345 F354 V357 D360 L361 N364 K367 E403 W407 G411 F414 L433 L441 H445 V452 F453 A456 L470 V519 F3 F4 V37 F46 V49 D52 L53 N56 K59 E95 W99 G103 F106 L125 L133 H137 V144 F145 A148 L162 V211 Q96JA3 PTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKAKFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVAALTVKEGDHQKEAFSIGMQRDLSLYLPAMEKQLAILDTLYEVHGLESDEVV 5kdi B 1.45 BS01 6S8 B 1 V345 L346 V353 F354 V357 D360 N364 K367 E403 W407 G411 F414 L415 F418 H445 V452 F453 A456 V519 V37 L38 V45 F46 V49 D52 N56 K59 E95 W99 G103 F106 L107 F110 H137 V144 F145 A148 V211 Q96JA3 PTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKAKFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVAALTVKEGDHQKEAFSIGMQRDLSLYLPAMEKQLAILDTLYEVHGLESDEVV 5lw1 B 3.20 BS01 III C 1 Q117 V118 M121 L123 E126 R127 Y130 S161 D162 C163 H286 V323 W324 D326 E329 Q110 V111 M114 L116 E119 R120 Y123 S154 D155 C156 H279 V316 W317 D319 E322 2.7.11.24 P45983 NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMD 5lw1 B 3.20 BS02 ADN B 1 G33 V40 A53 M108 E109 M111 N114 S155 L168 G26 V33 A46 M101 E102 M104 N107 S148 L161 2.7.11.24 P45983 NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMD 5lw1 E 3.20 BS01 III F 1 Q117 V118 M121 R127 Y130 S161 D162 V323 W324 D326 E329 Q110 V111 M114 R120 Y123 S154 D155 V316 W317 D319 E322 2.7.11.24 P45983 NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMD 5lw1 E 3.20 BS02 ADN E 1 G33 V40 A53 I86 M108 E109 M111 N114 S155 L168 G26 V33 A46 I79 M101 E102 M104 N107 S148 L161 2.7.11.24 P45983 NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMD 5lw1 H 3.20 BS01 III I 1 V118 M121 R127 Y130 S161 D162 C163 H286 V323 W324 D326 E329 V111 M114 R120 Y123 S154 D155 C156 H279 V316 W317 D319 E322 2.7.11.24 P45983 NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMD 5lw1 H 3.20 BS02 ADN H 1 G33 S34 V40 A53 M108 E109 M111 N114 S155 L168 G26 S27 V33 A46 M101 E102 M104 N107 S148 L161 2.7.11.24 P45983 NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMD 5n0k A 2.30 BS01 CU A 1 H162 H974 H1014 H162 H974 H1014 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n0k A 2.30 BS02 CU A 2 H275 C318 H323 L328 H275 C318 H323 L328 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n0k A 2.30 BS03 CU A 3 H101 H103 H972 H974 H101 H103 H972 H974 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n0k A 2.30 BS04 CU A 4 L968 H969 C1015 H1020 M1025 L968 H969 C1015 H1020 M1025 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n0k A 2.30 BS06 CU A 6 H631 C674 H679 M684 H631 C674 H679 M684 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n0k A 2.30 BS07 CU A 7 H596 D678 H596 D678 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n0k A 2.30 BS09 CU A 9 H290 D292 G459 K512 H290 D292 G459 K512 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n0k A 2.30 BS10 CA A 1 K109 Q124 D127 D128 K109 Q124 D127 D128 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n4l A 3.20 BS06 CA A 1 K109 E112 A114 D118 Q124 D127 D128 K109 E112 A114 D118 Q124 D127 D128 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n4l B 3.20 BS01 CU B 1 H969 C1015 V1017 H1020 M1025 H969 C1015 V1017 H1020 M1025 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n4l B 3.20 BS04 CU B 4 H631 C674 T676 H679 M684 H631 C674 T676 H679 M684 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n4l B 3.20 BS07 CA B 1 K109 E112 D118 T120 Q124 D127 D128 K109 E112 D118 T120 Q124 D127 D128 G3V7K3 29177316 REKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGLLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSALFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENLTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKQRGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGILGPLIHADVGDKVKVVFKNMASRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYSDHPEKVNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPN 5n81 A 1.60 BS01 8Q2 A 1 F212 F216 F232 D233 V234 S237 A299 G300 S301 A302 N319 A320 Y321 G322 P323 T324 L327 V328 D411 F423 F181 F185 F201 D202 V203 S206 A268 G269 S270 A271 N288 A289 Y290 G291 P292 T293 L296 V297 D380 F392 5.1.1.11 P09095 ALVPYAQGKSIHQLFEEQAEAFPDRVAIVFENRRLSYQELNRKANQLARALLEKGVQTDSIVGVMMEKSIENVIAILAVLKAGGAYVPIDIEYPRDRIQYILQDSQTKIVLTQKSVSQLVHDVGYSGEVVVLDEEQLDARETANLHQPSKPTDLAYVIYTSGKPKGTMLEHKGIANLQSFFQNSFGVTEQDRIGLFASMSFDVSVSEMFMALLSGASLYILSKQTIHDFAAFEHYLSENELTIITLPPTYLTHLTPERITSLRIMITAGSASSAPLVNKWKDKLRYINAYGPTECLVATIWEAPSNQLSVQSVPIGKPIQNTHIYIVNEDLQLLPTGSEGELCIGGVGLARGYWNRPDLTAEKFVDNPFVPGEKMYRTGDLAKWLTDGTIEFLGRI 5n82 A 1.71 BS01 8PZ A 1 F232 D233 V234 W237 A299 G300 S301 A302 N319 A320 Y321 G322 P323 T324 L327 V328 D411 F423 F201 D202 V203 W206 A268 G269 S270 A271 N288 A289 Y290 G291 P292 T293 L296 V297 D380 F392 5.1.1.11 P09095 LVPYAQGKSIHQLFEEQAEAFPDRVAIVFENRRLSYQELNRKANQLARALLEKGVQTDSIVGVMMEKSIENVIAILAVLKAGGAYVPIDIEYPRDRIQYILQDSQTKIVLTQKSVSQLVHDVGYSGEVVVLDEEQLDARETANLHQPSKPTDLAYVIYTSGGKPKGTMLEHKGIANLQSFFQNSFGVTEQDRIGLFASMSFDVSVWEMFMALLSGASLYILSKQTIHDFAAFEHYLSENELTIITLPPTYLTHLTPERITSLRIMITAGSASSAPLVNKWKDKLRYINAYGPTECLVATIWEAPSNQLSVQSVPIGKPIQNTHIYIVNEDLQLLPTGSEGELCIGGVGLARGYWNRPDLTAEKFVDNPFVPGEKMYRTGDLAKWLTDGTIEFLGRI 5njj A 2.70 BS01 III H 1 S52 R53 I111 E112 K113 V114 S115 F116 C117 A118 R132 W139 S155 H156 G159 F162 S26 R27 I85 E86 K87 V88 S89 F90 C91 A92 R106 W113 S129 H130 G133 F136 P49757 TDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERK 5njj B 2.70 BS01 III F 1 R53 I111 E112 K113 V114 S115 F116 C117 A118 R132 S155 H156 G159 F162 R27 I82 E83 K84 V85 S86 F87 C88 A89 R103 S126 H127 G130 F133 P49757 TDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLER 5njj D 2.70 BS01 III G 1 R53 I111 E112 K113 V114 S115 F116 C117 A118 P119 R132 W139 S155 H156 G159 F162 L166 K169 R26 I84 E85 K86 V87 S88 F89 C90 A91 P92 R105 W112 S128 H129 G132 F135 L139 K142 P49757 DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQ 5njk A 3.13 BS01 III G 1 R53 I111 E112 K113 V114 S115 F116 C117 R132 W139 S155 H156 G159 F162 K169 R29 I87 E88 K89 V90 S91 F92 C93 R108 W115 S131 H132 G135 F138 K145 P49757 WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQK 5njk E 3.13 BS01 III H 1 R53 I111 E112 K113 V114 S115 F116 C117 R132 W139 S155 H156 F162 L166 R26 I75 E76 K77 V78 S79 F80 C81 R96 W103 S119 H120 F126 L130 P49757 DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERK 5nwx A 2.51 BS01 III B 1 G270 I273 S274 I275 T277 E289 R293 I296 F300 A310 R311 G11 I14 S15 I16 T18 E30 R34 I37 F41 A51 R52 2.3.1.48 P70365 29203888 ESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTRCKLCYPFIMGIHIIDR 5o6b A 2.03 BS01 NUC C 1 T290 G291 T301 H303 S304 G309 L310 V385 K387 S463 T464 R465 N526 N533 S703 H705 K706 F723 E724 T55 G56 T66 H68 S69 G74 L75 V150 K152 S224 T225 R226 N287 N294 S453 H455 K456 F473 E474 3.6.4.12 P07271 29202194 GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADE 5o6b A 2.03 BS02 ADP A 1 G236 L237 Q241 G261 T262 G263 K264 S265 I266 F416 R417 G1 L2 Q6 G26 T27 G28 K29 S30 I31 F177 R178 3.6.4.12 P07271 29202194 GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADE 5o6b A 2.03 BS03 ALF A 1 A260 G261 K264 E342 Q381 R417 G709 R734 A25 G26 K29 E107 Q146 R178 G459 R484 3.6.4.12 P07271 29202194 GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADE 5o6b B 2.03 BS01 NUC C 1 T464 R502 T228 R266 3.6.4.12 P07271 29202194 LSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKPVSPLDSSVFDFMKRIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTL 5o6b B 2.03 BS02 NUC D 1 S289 T290 G291 T301 H303 S304 G309 L310 K312 V385 K387 S463 T464 R465 K525 N526 N533 S703 H705 K706 F723 E724 S53 T54 G55 T65 H67 S68 G73 L74 K76 V149 K151 S227 T228 R229 K289 N290 N297 S446 H448 K449 F466 E467 3.6.4.12 P07271 29202194 LSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKPVSPLDSSVFDFMKRIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTL 5o6d A 3.28 BS01 NUC C 1 T290 G291 T301 H303 S304 G309 L310 V385 K387 T464 R465 N526 N533 S703 H705 K706 R721 F723 T54 G55 T65 H67 S68 G73 L74 V149 K151 T224 R225 N286 N293 S452 H454 K455 R470 F472 3.6.4.12 P07271 29202194 LSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADE 5o6d A 3.28 BS02 AGS A 1 L237 Q241 G261 G263 K264 S265 I266 E342 Q381 F416 R417 T711 R734 L1 Q5 G25 G27 K28 S29 I30 E106 Q145 F176 R177 T460 R483 3.6.4.12 P07271 29202194 LSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADE 5o6d A 3.28 BS03 MG A 1 S265 N296 G709 S29 N60 G458 3.6.4.12 P07271 29202194 LSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADE 5o6d B 3.28 BS01 NUC D 1 T290 G291 T301 H303 S304 G309 L310 V385 S386 S463 T464 L508 K525 N526 N533 S703 H705 K706 R721 F723 T54 G55 T65 H67 S68 G73 L74 V149 S150 S223 T224 L268 K285 N286 N293 S452 H454 K455 R470 F472 3.6.4.12 P07271 29202194 LSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADE 5o6d B 3.28 BS02 AGS B 1 L237 Q241 G261 T262 G263 K264 S265 I266 E342 Q381 F416 R417 G709 T711 R734 L1 Q5 G25 T26 G27 K28 S29 I30 E106 Q145 F176 R177 G458 T460 R483 3.6.4.12 P07271 29202194 LSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADE 5o6d B 3.28 BS03 MG B 1 S265 N296 D341 G709 S29 N60 D105 G458 3.6.4.12 P07271 29202194 LSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAVTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIGALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVSKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRKSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSAGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWSLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRIKAHQKVIDFYLTLSSAESAYKQLEADE 5oaf A 4.06 BS01 ADP A 1 H18 H20 G38 L39 V40 P72 G73 G75 K76 T77 A78 Y366 I374 R378 R404 H8 H10 G28 L29 V30 P62 G63 G65 K66 T67 A68 Y350 I358 R362 R388 3.6.4.12 Q9Y265 KTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETEGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQD 5oaf B 4.06 BS01 ADP A 1 E317 R353 E286 R322 3.6.4.12 Q9Y230 VTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDA 5oaf B 4.06 BS02 ADP B 1 A24 H25 H27 G45 M46 V47 Q78 P79 G80 T81 G82 K83 T84 A85 N329 Y362 I370 R374 R400 I403 A9 H10 H12 G30 M31 V32 Q63 P64 G65 T66 G67 K68 T69 A70 N298 Y331 I339 R343 R369 I372 3.6.4.12 Q9Y230 VTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDA 5oaf C 4.06 BS01 ADP C 1 S17 H18 G38 L39 V40 G73 T74 G75 K76 T77 Y366 I374 R378 R404 S7 H8 G28 L29 V30 G63 T64 G65 K66 T67 Y338 I346 R350 R376 3.6.4.12 Q9Y265 KTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQD 5oaf D 4.06 BS01 ADP C 1 R314 R353 R276 R315 3.6.4.12 Q9Y230 VTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDA 5oaf D 4.06 BS02 ADP D 1 H25 H27 P79 G80 T81 G82 K83 T84 A85 Y362 I370 R374 R400 I403 H10 H12 P64 G65 T66 G67 K68 T69 A70 Y324 I332 R336 R362 I365 3.6.4.12 Q9Y230 VTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDA 5oaf E 4.06 BS01 ADP E 1 H18 H20 V40 G73 T74 G75 K76 T77 Y366 I374 R404 H8 H10 V30 G63 T64 G65 K66 T67 Y356 I364 R394 3.6.4.12 Q9Y265 KTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQD 5oaf F 4.06 BS02 ADP F 1 A24 H25 H27 G45 M46 V47 G80 T81 G82 K83 T84 A85 Y362 R374 R400 A9 H10 H12 G30 M31 V32 G65 T66 G67 K68 T69 A70 Y318 R330 R356 3.6.4.12 Q9Y230 VTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFL 5ohj A 1.60 BS02 9VE A 1 S454 T517 M519 D564 L565 N567 P568 Y575 W578 T579 I582 F586 Q589 P602 M603 C604 S614 Q615 F618 I622 S132 T195 M197 D242 L243 N245 P246 Y253 W256 T257 I260 F264 Q267 P280 M281 C282 S292 Q293 F296 I300 3.1.4.53 Q07343 29200281 TSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQ 5on0 B 1.90 BS01 9YH B 1 Y22 M27 R97 W100 R137 Y382 W398 Y402 T490 Y20 M25 R95 W98 R135 Y380 W396 Y400 T488 P33590 29148757 PDEITTAWPVNVGPLNPHLYTPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFDAEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRPFRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITFNVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPSQYDPQKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYAPIATEIPFEQIKPV 5on4 A 2.30 BS01 9YK A 1 Y22 T23 M27 W100 R137 W398 H416 Y21 T22 M26 W99 R136 W397 H415 P33590 29148757 APDEITTAWPVNVGPLNPHLYTPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFDAEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRPFRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITFNVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPSQYDPQKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYAPIATEIPFEQIKP 5on4 B 2.30 BS01 9YK B 1 Y22 T23 M27 R97 W100 R137 W398 Y402 H416 Y21 T22 M26 R96 W99 R136 W397 Y401 H415 P33590 29148757 APDEITTAWPVNVGPLNPHLYTPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFDAEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRPFRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITFNVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPSQYDPQKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYAPIATEIPFEQIKP 5on8 A 1.60 BS01 9YH A 1 Y22 T23 M27 R97 W100 R137 W398 Y402 Y21 T22 M26 R96 W99 R136 W397 Y401 P33590 29148757 APDEITTAWPVNVGPLNPHLYTPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFDAEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRPFRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITFNVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPSQYDPQKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYAPIATEIPFEQIKP 5on9 A 1.70 BS01 9YH A 1 Y22 T23 M27 W100 R137 W398 Y21 T22 M26 W99 R136 W397 P33590 29148757 APDEITTAWPVNVGPLNPHLYTPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFDAEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRPFRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITFNVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPSQYDPQKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYAPIATEIPFEQIKP 5opf A 1.08 BS01 CU A 1 H37 H144 Y221 H1 H108 Y185 D9SZQ3 HGSVVDPASRSYSCWQRWGGDFQNPAMATQDPMCWQAWQADPNAMWNWNGLFREGVAGNHQGAIPDGQLCSGGRTQSGRYNALDTVGAWKTVPVTNNFRVKFFDQASHGADYIRVYVTKQGYNALTSPLRWSDLELVGQIGNTPASQWTREVDGVSIQIPANAPGRTGRHVVYTIWQASHLDQSYYLCSDVDFG 5osi A 2.52 BS01 III C 1 L25 L26 K30 Y163 Y165 V172 R176 L25 L26 K30 Y163 Y165 V172 R176 Q9UBQ0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP 5osi D 2.52 BS01 III F 1 L25 K30 L152 Y163 Y165 V172 V174 L25 K30 L152 Y163 Y165 V172 V174 Q9UBQ0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP 5osi G 2.52 BS01 III I 1 L25 L26 K30 I31 Y163 Y165 V172 V174 R176 L25 L26 K30 I31 Y163 Y165 V172 V174 R176 Q9UBQ0 MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP 5owp H 1.85 BS01 III D 1 N31 Y32 W33 V101 Q103 Y1041 P1065 W1100 S1102 W1105 N31 Y32 W33 V101 Q103 Y150 P174 W209 S211 W214 P01726 29166012 QVQLQESGGGLVQPGGSMKLSCVASGFTFSNYWMNWVRQSPEKGLEWVAEIRLKSNNYATHYAESVKGRFTISRDDSKSSVYLQMNNLRAEDTGIYYCTGVGQFAYWGQGTTVTVSDIVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGVPARFSGSLIGDKAALTITGAQTEDEAIYFCALWYSNHWVFGGGTKLTVLG 5u6v A 1.78 BS01 7WY A 1 W370 P371 F372 V376 L381 N429 H433 D434 V435 M438 W24 P25 F26 V30 L35 N83 H87 D88 V89 M92 P25440 SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 5ufm A 1.77 BS01 SAH A 1 L32 F36 Y40 W47 M53 G74 A75 G76 R79 D80 D95 L96 P119 V120 N135 G136 C137 Q141 L29 F33 Y37 W44 M50 G71 A72 G73 R76 D77 D92 L93 P116 V117 N132 G133 C134 Q138 Q2T5S0 AEPHYIDAQRAIAPVDAPLAAPHEYAAVLRSDFVSSYHDGRDVWTDEAAMRPASAILHAHLGRPAVVLDAGAGRGRDTAYFLEQGHRVTAVDLVEPPEWAPLAQRWGERVRFVACPVSELDGEARFDGALDNGCLHHQHPDAYGTYLARIHALLRPDGRFTISVFESDGPGRLYANHAQRLYREFTEPELAELLRAAHFTPVDSQRVPRPKAGLHYLVMTARKTD 5ufm A 1.77 BS02 AZ8 A 1 D10 R13 W47 G136 H139 H140 F168 R183 Y185 R212 Y219 D7 R10 W44 G133 H136 H137 F165 R180 Y182 R209 Y216 Q2T5S0 AEPHYIDAQRAIAPVDAPLAAPHEYAAVLRSDFVSSYHDGRDVWTDEAAMRPASAILHAHLGRPAVVLDAGAGRGRDTAYFLEQGHRVTAVDLVEPPEWAPLAQRWGERVRFVACPVSELDGEARFDGALDNGCLHHQHPDAYGTYLARIHALLRPDGRFTISVFESDGPGRLYANHAQRLYREFTEPELAELLRAAHFTPVDSQRVPRPKAGLHYLVMTARKTD 5ufm B 1.77 BS02 AZ8 B 1 D10 W47 M53 G136 H139 H140 F168 R183 Y185 R212 Y219 D5 W42 M48 G131 H134 H135 F163 R178 Y180 R207 Y214 Q2T5S0 PHYIDAQRAIAPVDAPLAAPHEYAAVLRSDFVSSYHDGRDVWTDEAAMRPASAILHAHLGRPAVVLDAGAGRGRDTAYFLEQGHRVTAVDLVEPPEWAPLAQRWGERVRFVACPVSELDGEARFDGALDNGCLHHQHPDAYGTYLARIHALLRPDGRFTISVFESDGPGRLYANHAQRLYREFTEPELAELLRAAHFTPVDSQRVPRPKAGLHYLVMTARKTD 5uph A 3.00 BS01 CLR A 1 V60 D212 V214 E230 V268 V277 V297 F339 T365 V367 I376 A379 A380 K381 E413 V415 V10 D146 V148 E155 V172 V181 V201 F226 T252 V254 I263 A266 A267 K268 E300 V302 Q14108 DSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTKIVEWNGKTSPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMI 5uph B 3.00 BS01 M6D A 1 R275 L324 N325 R186 L219 N220 Q14108 DSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDFTKIVEWNGKTSHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEICLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMI 5vra A 2.35 BS02 CLR A 1 P248 I252 C262 S263 P331 I335 C345 S346 P29274 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHV 5vua B 2.20 BS01 8GX B 1 L44 S46 F49 V52 A65 K67 I104 L120 E121 R122 D128 E171 L174 I185 D186 L9 S11 F14 V17 A30 K32 I69 L85 E86 R87 D93 E136 L139 I150 D151 2.7.11.1 P11309 29111719 SQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5vuc B 2.00 BS01 8GR B 1 L44 G45 S46 F49 V52 A65 K67 L120 E121 R122 D128 E171 L174 I185 D186 L9 G10 S11 F14 V17 A30 K32 L85 E86 R87 D93 E136 L139 I150 D151 2.7.11.1 P11309 29111719 SQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5w11 A 2.31 BS01 CTR A 1 N37 W38 Y51 N104 I105 R108 D180 K182 D199 N201 Y248 D373 D374 H375 N37 W38 Y51 N104 I105 R108 D180 K182 D199 N201 Y248 D373 D374 H375 3.2.1.176 G2Q665 QNACTLTAENHPSLTWSKCTSGGSCTSVQGSITIDANWRWTHRTDSATNCYEGNKWDTSYCSDGPSCASKCCIDGADYSSTYGITTSGNSLNLKFVTKGQYSTNIGSRTYLMESDTKYQMFQLLGNEFTFDVDVSNLGCGLNGALYFVSMDADGGMSKYSGNKAGAKYGTGYCDSQCPRDLKFINGEANVENWQSSTNDANAGTGKYGSCCSEMDVWEANNMAAAFTPHPCTVIGQSRCEGDSCGGTYSTDRYAGICDPDGCDFNSYRQGNKTFYGKGMTVDTTKKITVVTQFLKNSAGELSEIKRFYVQNGKVIPNSESTIPGVEGNSITQDWCDRQKAAFGDVTDFQDKGGMVQMGKALAGPMVLVMSIWDDHAVNMLWLDSTWPIDGAGKPGAERGACPTTSGVPAEVEAEAPNSNVIFSNIRFGPIGSTVSGL 5w11 A 2.31 BS02 CTR A 2 Q176 T247 Y248 R252 P259 D260 R268 D344 W372 D374 V377 W381 R398 Q176 T247 Y248 R252 P259 D260 R268 D344 W372 D374 V377 W381 R398 3.2.1.176 G2Q665 QNACTLTAENHPSLTWSKCTSGGSCTSVQGSITIDANWRWTHRTDSATNCYEGNKWDTSYCSDGPSCASKCCIDGADYSSTYGITTSGNSLNLKFVTKGQYSTNIGSRTYLMESDTKYQMFQLLGNEFTFDVDVSNLGCGLNGALYFVSMDADGGMSKYSGNKAGAKYGTGYCDSQCPRDLKFINGEANVENWQSSTNDANAGTGKYGSCCSEMDVWEANNMAAAFTPHPCTVIGQSRCEGDSCGGTYSTDRYAGICDPDGCDFNSYRQGNKTFYGKGMTVDTTKKITVVTQFLKNSAGELSEIKRFYVQNGKVIPNSESTIPGVEGNSITQDWCDRQKAAFGDVTDFQDKGGMVQMGKALAGPMVLVMSIWDDHAVNMLWLDSTWPIDGAGKPGAERGACPTTSGVPAEVEAEAPNSNVIFSNIRFGPIGSTVSGL 5w2m A 3.70 BS01 NUC E 1 Y333 P350 K352 P353 W354 G356 L357 K358 Y359 Y144 P161 K163 P164 W165 G167 L168 K169 Y170 3.5.4.- Q8IUX4 29191651 NPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 5w2m A 3.70 BS02 ZN A 1 H247 H249 H58 H60 3.5.4.- Q8IUX4 29191651 NPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 5w2m B 3.70 BS01 NUC E 1 Y333 K337 P350 F351 K352 P353 K355 G356 L357 K358 Y359 Y144 K148 P161 F162 K163 P164 K166 G167 L168 K169 Y170 3.5.4.- Q8IUX4 29191651 NPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 5w2m C 3.70 BS01 NUC E 1 Y333 P353 W354 K355 G356 K358 Y359 Y144 P164 W165 K166 G167 K169 Y170 3.5.4.- Q8IUX4 29191651 NPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 5w2m D 3.70 BS01 NUC E 1 Y333 W354 G356 L357 K358 Y359 Y144 W165 G167 L168 K169 Y170 3.5.4.- Q8IUX4 29191651 NPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 5w2m D 3.70 BS02 NUC N 1 K352 K355 K163 K166 3.5.4.- Q8IUX4 29191651 NPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 5w2m M 3.70 BS02 NUC N 1 Y333 P353 W354 G356 L357 K358 Y359 Y144 P164 W165 G167 L168 K169 Y170 3.5.4.- Q8IUX4 29191651 NPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 5w8q A 1.17 BS01 BU4 A 1 Y31 L65 T189 F192 F193 G206 Q207 F210 Y22 L56 T180 F183 F184 G197 Q198 F201 2.3.1.177 K9MST3 29199980 QHAKILAIGTANPPNVYHQKDYPDFLFRVTKNEHRTDLREKFDRICEKSRTKKRYLHLTEEMLKANPNIYTYGAPSLDVRQDICNIEVPKLGQEAALKAIKEWGQPISRITHLIFCTASCVDMPGCDFQLIKLLGLDPSVTRTMIYEAGCYAGATVLRMAKDFAENNKGARVLVVCAEITTVFFHGLTDTHLDILVGQALFADGASAVIVGANPEPEIERPLFEIVACRQTILPNSEHGVVANIREMGFNYYLSGDVPKFVGGNVVDFMTKTFEKVDGKKKDWNSLFFSVHPGGPAIVDQVEEKLGLKEGKLRATRHVLSEYGNMGAPTVHFILDEMRNKSIEEGKTTTGEGLEWGVVIGIGPGLTVETAVLRSESIRC 5w8q B 1.17 BS01 BU4 B 1 Y31 R63 L65 T189 F192 F193 G206 Q207 F210 Y22 R54 L56 T180 F183 F184 G197 Q198 F201 2.3.1.177 K9MST3 29199980 QHAKILAIGTANPPNVYHQKDYPDFLFRVTKNEHRTDLREKFDRICEKSRTKKRYLHLTEEMLKANPNIYTYGAPSLDVRQDICNIEVPKLGQEAALKAIKEWGQPISRITHLIFCTASCVDMPGCDFQLIKLLGLDPSVTRTMIYEAGCYAGATVLRMAKDFAENNKGARVLVVCAEITTVFFHGLTDTHLDILVGQALFADGASAVIVGANPEPEIERPLFEIVACRQTILPNSEHGVVANIREMGFNYYLSGDVPKFVGGNVVDFMTKTFEKVDGKKKDWNSLFFSVHPGGPAIVDQVEEKLGLKEGKLRATRHVLSEYGNMGAPTVHFILDEMRNKSIEEGKTTTGEGLEWGVVIGIGPGLTVETAVLRSESIR 5wc4 A 1.20 BS02 BYC A 1 K50 R53 I54 K57 S58 C159 F192 V205 L209 F210 V249 L262 S263 G264 P267 G302 G303 P304 A305 I306 K41 R44 I45 K48 S49 C150 F183 V196 L200 F201 V240 L253 S254 G255 P258 G293 G294 P295 A296 I297 2.3.1.177 K9MST3 29199980 QHAKILAIGTANPPNVYHQKDYPDFLFRVTKNEHRTDLREKFDRICEKSRTKKRYLHLTEEMLKANPNIYTYGAPSLDVRQDICNIEVPKLGQEAALKAIKEWGQPISRITHLIFCTASCVDMPGCDFQLIKLLGLDPSVTRTMIYEAGCYAGATVLRMAKDFAENNKGARVLVVCAEITTVFFHGLTDTHLDILVGQALFADGASAVIVGANPEPEIERPLFEIVACRQTILPNSEHGVVANIREMGFNYYLSGDVPKFVGGNVVDFMTKTFEKVDGKKKDWNSLFFSVHPGGPAIVDQVEEKLGLKEGKLRATRHVLSEYGNMGAPTVHFILDEMRNKSIEEGKTTTGEGLEWGVVIGIGPGLTVETAVLRSESIRC 5wej A 1.95 BS01 V45 A 1 H30 I109 V114 T134 P136 C139 H157 A158 A159 A160 H30 I109 V113 T133 P135 C138 H156 A157 A158 A159 3.6.1.15,3.4.22.66,2.7.7.48 Q83883 APPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQRLVHGQSGMLLTGANAKGMDLGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTVVCAVQA 5wej B 1.95 BS01 V45 B 1 H30 Q110 T134 C139 H157 A158 A159 A160 H27 Q107 T124 C129 H147 A148 A149 A150 3.6.1.15,3.4.22.66,2.7.7.48 Q83883 TLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHGQSGMLLTGLGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTVVCAVQ 5whc A 2.55 BS01 AJJ A 1 C300 R301 L304 D305 Y348 D349 H403 C92 R93 L96 D97 Y140 D141 H195 3.4.19.12 Q93009 29166018 KHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQK 5wjk A 2.00 BS01 HEM A 1 T40 K43 F44 R46 H65 T68 A72 L90 S93 H94 H98 I100 Y104 L105 T39 K42 F43 R45 H64 T67 A71 L89 S92 H93 H97 I99 Y103 L104 P02185 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5wkn A 2.65 BS01 III C 1 F270 L271 L273 K274 L277 R280 L284 A285 K297 M300 R311 F220 L221 L223 K224 L227 R230 L234 A235 K247 M250 R261 Q88435 PVIRVFILTSNNPELRSRLLLFCLRIVLSNGARDSHRFGALLTMFSLPSATMLNHVKLADQRVEIDGFEEGSFRLIPNARSGMSRGEINAYAALAEDLPDTLNHATPFVDSEVEGTAWDEIETFLDMCYSVLMQAWIVTCKIEKRLQKYRQQGRINPRYLLQPEARRIIQNVIRKGMVVRHFLTFELQLARAQSLVSNRYYAMVGDVGKYIENCGMGGFFLTLKYALGTRWPTLALAAFSGELTKLKSLMALYQTLGEQARYLALLESPHLMDFAAANYPLLYSYAMGIGYVLDVNMRNYAFSRSYMNKTYFQLGMETARKQM 5wkn B 2.65 BS01 III D 1 R241 K259 F270 L271 L273 L277 R280 L293 K297 M300 R311 R197 K215 F226 L227 L229 L233 R236 L249 K253 M256 R267 Q88435 PVIRVFILTSNNPELRSRLLLFCLRIVLSNGARDSHRFGALLTMFSLPSATMLNHVKLADQSPEADIERVEIDGFEEGSFRLIPNARSGMSRGEINAYAALAEDLPDTLNHATPFVDSEVEGTAWDEIETFLDMCYSVLMQAWIVTCKEKRLQKYRQQGRINPRYLLQPEARRIIQNVIRKGMVVRHFLTFELQLARAQSLVSNRYYAMVGDVGKYIENCGMGGFFLTLKYALGTRWPTLALAAFSGELTKLKSLMALYQTLGEQARYLALLESPHLMDFAAANYPLLYSYAMGIGYVLDVNMRNYAFSRSYMNKTYFQLGMETARKQ 5wkt A 3.20 BS01 III B 1 L72 R135 V138 V139 K141 A233 T242 A246 E249 V250 L72 R135 V138 V139 K141 A233 T242 A246 E249 V250 P02699 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN 5wkt A 3.20 BS02 TRE A 1 K66 R69 Y74 K66 R69 Y74 P02699 MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN 5wp6 A 3.80 BS01 DVT A 1 R1138 R1141 R1147 R922 R925 R931 Q8TD43 EQSWIPKIFKKKTCHTTEKPTDAYGELDFTGAGRKHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTRQGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGSYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQAPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGGSLASGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQALEHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLKVLEREVQQCSRVLGWVAEAL 5wp6 A 3.80 BS02 DVT B 1 T160 R214 T109 R163 Q8TD43 EQSWIPKIFKKKTCHTTEKPTDAYGELDFTGAGRKHSNFLRLSDRTDPAAVYSLVTRTWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGVQFPLDYNYSAFFLVDDGTHGCLGGENRFRLRLESYISQQKTGVGGTGIDIPVLLLLIDGDEKMLTRIENATQAQLPCLLVAGSGGAADCLAETLEDTRQGEARDRIRRFFPKGDLEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLKALVKACGSYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQAPWSDLLLWALLLNRAQMAMYFWEMGSNAVSSALGACLLLRVMARLEPDAEEAARRKDLAFKFEGMGVDLFGECYRSSEVRAARLLLRRCPLWGDATCLQLAMQADARAFFAQDGVQSLLTQKWWGDMASTTPIWALVLAFFCPPLIYTRLITFRRCLRRWFHFWGAPVTIFMGNVVSYLLFLLLFSRVLLVDFQPAPPGSLELLLYFWAFTLLCEELRQGLSGGSLASGGPGPGHASLSQRLRLYLADSWNQCDLVALTCFLLGVGCRLTPGLYHLGRTVLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREFHSRPALAPPFIVISHLRLLLRQALEHFRVYLSKEAERKLLTWESVHKENFLLARARDKRESDSERLKRTSQKVDLALKQLGHIREYEQRLKVLEREVQQCSRVLGWVAEAL 5ws3 A 2.30 BS01 7MA A 1 T111 P131 Q134 Q187 M191 E212 H224 F227 I320 S321 N324 H350 V353 Y354 T77 P97 Q100 Q153 M157 E178 H190 F193 I443 S444 N447 H473 V476 Y477 O43614 DDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQGIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAGDPGELANAILKALELSRSDLSKFRENCKKRAMSFSKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCC 5wt1 A 2.60 BS01 NUC C 1 R8 A11 K12 L15 K19 G26 K29 R32 V37 F39 R62 R65 Q66 I67 Y68 K69 N70 L83 R85 L86 D87 L115 Y116 K118 R125 F127 H128 R133 R135 K151 E152 N153 G154 F165 R169 K171 G172 P262 K263 F284 D317 Y318 K319 P320 H321 Y323 K324 R8 A11 K12 L15 K19 G26 K29 R32 V37 F39 R62 R65 Q66 I67 Y68 K69 N70 L83 R85 L86 D87 L115 Y116 K118 R125 F127 H128 R133 R135 K151 E152 N153 G154 F165 R169 K171 G172 P262 K263 F284 D317 Y318 K319 P320 H321 Y323 K324 2.1.1.228 Q9V2G1 MSGVKVRREDAKKVLELLKSVGILDGKRKAIRDEKYVIFPVTDTNIAKSLGLEVVDVELPMRPERQIYKNLEDLLPREIFKKLGRLDIVGDIAIVSIPDEILSEREVIVSAIRKLYPKVKVIARRGFHSGLYRIRELEVIWGENRLHTIHKENGVLIKVDLSKVFFNPRMKGERYRIAQLVNDGERILVPFAGVIPYPLVIARFKNVEVYAVEINEFAVKLAEENLELNRDRLKGKIKIIHGDVFEVLPNLPNFDRVVSPTPKGVDALSLTLSKAEKFLHYYDFVHESEIERFRERVLEECRRQGKECRVSVRKVSDYKPHVYKVCADVEIL 5wt1 A 2.60 BS02 SAH A 1 L131 Y132 F165 R174 F191 P196 Y197 E213 I214 G242 D243 V244 P260 P262 L131 Y132 F165 R174 F191 P196 Y197 E213 I214 G242 D243 V244 P260 P262 2.1.1.228 Q9V2G1 MSGVKVRREDAKKVLELLKSVGILDGKRKAIRDEKYVIFPVTDTNIAKSLGLEVVDVELPMRPERQIYKNLEDLLPREIFKKLGRLDIVGDIAIVSIPDEILSEREVIVSAIRKLYPKVKVIARRGFHSGLYRIRELEVIWGENRLHTIHKENGVLIKVDLSKVFFNPRMKGERYRIAQLVNDGERILVPFAGVIPYPLVIARFKNVEVYAVEINEFAVKLAEENLELNRDRLKGKIKIIHGDVFEVLPNLPNFDRVVSPTPKGVDALSLTLSKAEKFLHYYDFVHESEIERFRERVLEECRRQGKECRVSVRKVSDYKPHVYKVCADVEIL 5wt1 B 2.60 BS01 NUC F 1 R8 A11 K12 G26 K29 F39 R62 R65 Q66 I67 Y68 K69 N70 L83 R85 L86 L115 Y116 R125 F127 H128 R133 R135 K151 E152 N153 G154 F165 R169 K171 G172 P262 K263 F284 D317 Y318 K319 P320 H321 Y323 R6 A9 K10 G24 K27 F37 R60 R63 Q64 I65 Y66 K67 N68 L81 R83 L84 L113 Y114 R123 F125 H126 R131 R133 K149 E150 N151 G152 F163 R167 K169 G170 P260 K261 F282 D315 Y316 K317 P318 H319 Y321 2.1.1.228 Q9V2G1 GVKVRREDAKKVLELLKSVGILDGKRKAIRDEKYVIFPVTDTNIAKSLGLEVVDVELPMRPERQIYKNLEDLLPREIFKKLGRLDIVGDIAIVSIPDEILSEREVIVSAIRKLYPKVKVIARRGFHSGLYRIRELEVIWGENRLHTIHKENGVLIKVDLSKVFFNPRMKGERYRIAQLVNDGERILVPFAGVIPYPLVIARFKNVEVYAVEINEFAVKLAEENLELNRDRLKGKIKIIHGDVFEVLPNLPNFDRVVSPTPKGVDALSLTLSKAEKFLHYYDFVHESEIERFRERVLEECRRQGKECRVSVRKVSDYKPHVYKVCADVEIL 5wt1 B 2.60 BS02 SAH B 1 L131 Y132 F165 M170 F191 A192 G193 P196 Y197 E213 I214 G242 D243 V244 P260 P262 L129 Y130 F163 M168 F189 A190 G191 P194 Y195 E211 I212 G240 D241 V242 P258 P260 2.1.1.228 Q9V2G1 GVKVRREDAKKVLELLKSVGILDGKRKAIRDEKYVIFPVTDTNIAKSLGLEVVDVELPMRPERQIYKNLEDLLPREIFKKLGRLDIVGDIAIVSIPDEILSEREVIVSAIRKLYPKVKVIARRGFHSGLYRIRELEVIWGENRLHTIHKENGVLIKVDLSKVFFNPRMKGERYRIAQLVNDGERILVPFAGVIPYPLVIARFKNVEVYAVEINEFAVKLAEENLELNRDRLKGKIKIIHGDVFEVLPNLPNFDRVVSPTPKGVDALSLTLSKAEKFLHYYDFVHESEIERFRERVLEECRRQGKECRVSVRKVSDYKPHVYKVCADVEIL 5wt2 A 2.30 BS01 PLP A 1 C72 A73 T74 H104 D180 V182 Q183 S203 H205 K206 C71 A72 T73 H103 D179 V181 Q182 S202 H204 K205 2.8.1.7 O25008 VQRIYLDNNATTRIDPKVKEIMDPFLRDHYGNPSSLHQFGTETHPAIAEALDKLYKGINARDIDDVIITSCATESNNWVLKGVYFDECLKKGKNHIVTTVAEHPAVRSTCNFLESLGVEVTYLPINEHGSITAEQVREAITEKTALVSVMWANNETGLIFPIEEIGAICKEKGVLFHTDAVQAIGKIPVDVLKANADFLSFSAHKFHGPKGIGGLYIRSGVGLTPLFHGGEHMNGRRSGTLNVPYIVGMGEAMKLAVEHLDYEKEVVGKLRDKLEEALLKIPDVMVVGDRIHRVPNTTLVSVRGIEGEAMLWDLNRSNIAASTGSATAIRLSLSRFNTEAEIDKTIEVFSQAAVR 5wt3 A 3.20 BS01 NUC C 1 R8 A11 K12 R62 R65 Q66 I67 Y68 K69 N70 R85 L86 D87 Y116 R125 F127 H128 R133 R135 K151 E152 N153 G154 R169 K171 G172 P262 K263 F284 D317 Y318 K319 P320 H321 Y323 R8 A11 K12 R62 R65 Q66 I67 Y68 K69 N70 R85 L86 D87 Y116 R125 F127 H128 R133 R135 K151 E152 N153 G154 R169 K171 G172 P262 K263 F284 D317 Y318 K319 P320 H321 Y323 2.1.1.228 Q9V2G1 MSGVKVRREDAKKVLELLKSVGILDGKRKAIRDEKYVIFPVTDTNIAKSLGLEVVDVELPMRPERQIYKNLEDLLPREIFKKLGRLDIVGDIAIVSIPDEILSEREVIVSAIRKLYPKVKVIARRGFHSGLYRIRELEVIWGENRLHTIHKENGVLIKVDLSKVFFNPRMKGERYRIAQLVNDGERILVPFAGVIPYPLVIARFKNVEVYAVEINEFAVKLAEENLELNRDRLKGKIKIIHGDVFEVLPNLPNFDRVVSPTPKGVDALSLTLSKAEKFLHYYDFVHESEIERFRERVLEECRRQGKECRVSVRKVSDYKPHVYKVCADVEIL 5wt3 A 3.20 BS02 MTA A 1 F165 F191 G193 E213 I214 N215 G242 D243 V244 P262 F165 F191 G193 E213 I214 N215 G242 D243 V244 P262 2.1.1.228 Q9V2G1 MSGVKVRREDAKKVLELLKSVGILDGKRKAIRDEKYVIFPVTDTNIAKSLGLEVVDVELPMRPERQIYKNLEDLLPREIFKKLGRLDIVGDIAIVSIPDEILSEREVIVSAIRKLYPKVKVIARRGFHSGLYRIRELEVIWGENRLHTIHKENGVLIKVDLSKVFFNPRMKGERYRIAQLVNDGERILVPFAGVIPYPLVIARFKNVEVYAVEINEFAVKLAEENLELNRDRLKGKIKIIHGDVFEVLPNLPNFDRVVSPTPKGVDALSLTLSKAEKFLHYYDFVHESEIERFRERVLEECRRQGKECRVSVRKVSDYKPHVYKVCADVEIL 5wt4 A 2.92 BS01 C6P A 1 C72 A73 T74 H104 N155 D180 Q183 S203 H205 K206 C71 A72 T73 H103 N154 D179 Q182 S202 H204 K205 2.8.1.7 O25008 VQRIYLDNNATTRIDPKVKEIMDPFLRDHYGNPSSLHQFGTETHPAIAEALDKLYKGINARDIDDVIITSCATESNNWVLKGVYFDECLKKGKNHIVTTVAEHPAVRSTCNFLESLGVEVTYLPINEHGSITAEQVREAITEKTALVSVMWANNETGLIFPIEEIGAICKEKGVLFHTDAVQAIGKIPVDVLKANADFLSFSAHKFHGPKGIGGLYIRSGVGLTPLFHGGEHMNGRRSGTLNVPYIVGMGEAMKLAVEHLDYEKEVVGKLRDKLEEALLKIPDVMVVGDRIHRVPNTTLVSVRGIEGEAMLWDLNRSNIAASTGTAIRLSLSRFNTEAEIDKTIEVFSQAAVRLRNIS 5wt6 A 3.30 BS01 PDA A 1 N10 C72 A73 T74 H104 N155 D180 V182 Q183 S203 H205 K206 R354 N9 C71 A72 T73 H103 N154 D179 V181 Q182 S202 H204 K205 R335 2.8.1.7 O25008 VQRIYLDNNATTRIDPKVKEIMDPFLRDHYGNPSSLHQFGTETHPAIAEALDKLYKGINARDIDDVIITSCATESNNWVLKGVYFDECLKKGKNHIVTTVAEHPAVRSTCNFLESLGVEVTYLPINEHGSITAEQVREAITEKTALVSVMWANNETGLIFPIEEIGAICKEKGVLFHTDAVQAIGKIPVDVLKANADFLSFSAHKFHGPKGIGGLYIRSGVGLTPLFHGGEHMNGRRSGTLNVPYIVGMGEAMKLAVEHLDYEKEVVGKLRDKLEEALLKIPDVMVVGDRIHRVPNTTLVSVRGIEGEAMLWDLNRSNIAASTGSACASAHTAIRLSLSRFNTEAEIDKTIEVFSQAAVRLRNISS 5wtl A 2.30 BS01 CA A 1 D198 D200 D202 I204 D209 D1 D3 D5 I7 D12 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl A 2.30 BS02 CA A 2 D200 D202 D209 C211 P212 V214 G216 G222 D3 D5 D12 C14 P15 V17 G19 G25 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl A 2.30 BS04 CA A 4 D227 D229 D236 C238 P239 V241 G249 D30 D32 D39 C41 P42 V44 G52 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl A 2.30 BS06 CA A 6 D254 D256 D263 C265 V268 A269 G270 G276 D57 D59 D66 C68 V71 A72 G73 G79 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl A 2.30 BS08 CA A 8 D281 D283 D290 C292 P293 V295 A296 G297 G303 D84 D86 D93 C95 P96 V98 A99 G100 G106 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl A 2.30 BS09 CA A 9 D308 D310 D312 V314 D319 D111 D113 D115 V117 D122 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl A 2.30 BS11 CA A 11 E424 Q426 E227 Q229 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl B 2.30 BS02 CA B 2 D200 D202 D209 C211 V214 P215 G216 G222 D3 D5 D12 C14 V17 P18 G19 G25 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl B 2.30 BS04 CA B 4 D227 D229 D236 C238 P239 V241 K242 G243 G249 D30 D32 D39 C41 P42 V44 K45 G46 G52 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl B 2.30 BS10 CA B 10 D310 D312 D319 C321 V324 A325 G332 D113 D115 D122 C124 V127 A128 G135 C2M2E7 DTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl C 2.30 BS04 CA C 4 D227 D229 D236 C238 P239 V241 K242 G249 D32 D34 D41 C43 P44 V46 K47 G54 C2M2E7 SKDTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl C 2.30 BS08 CA C 8 D281 D283 D290 C292 P293 V295 A296 G303 D86 D88 D95 C97 P98 V100 A101 G108 C2M2E7 SKDTDKDGIPDNKDACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl D 2.30 BS01 CA D 1 D209 C211 V214 P215 G216 G222 D1 C3 V6 P7 G8 G14 C2M2E7 DACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wtl D 2.30 BS08 CA D 8 D308 D310 D312 V314 D316 D319 D100 D102 D104 V106 D108 D111 C2M2E7 DACPEVPGLKEFNGCPDTDGDGIPDKDDACPQVKGPKEFNGCPDTDGDGIPDKDDACPEVAGPKEFNGCPDTDGDGIPDKDDKCPDVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGPASNKGCPEPDEKEQKQLNQYAKTILFDTGKATIKFQSAEVLNQIINVLKKYPNSRFRIEGHTDSTGKKAKNMILSQNRADAVKVYLIQGGIDAGRLESQGFGPEKPIASNKNKKGRELNRRVEINLIK 5wyx A 2.40 BS01 CU8 A 1 F495 A518 Q519 V520 F427 A450 Q451 V452 Q9NR97 29155428 RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE 5wyx A 2.40 BS02 CU8 B 1 F261 Y348 G351 S352 G376 V378 F405 F219 Y306 G309 S310 G334 V336 F363 Q9NR97 29155428 RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE 5wyx B 2.40 BS01 CU8 A 1 F261 Y348 K350 G351 S352 G376 V378 F405 F218 Y305 K307 G308 S309 G333 V335 F362 Q9NR97 29155428 RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLEL 5wyx B 2.40 BS02 CU8 B 1 F494 F495 A518 Q519 V520 F426 F427 A450 Q451 V452 Q9NR97 29155428 RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLEL 5wyz A 2.30 BS01 7VF A 1 F494 F495 A518 Q519 V520 Y567 F426 F427 A450 Q451 V452 Y499 Q9NR97 29155428 RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE 5wyz A 2.30 BS02 7VF B 1 F261 Y348 K350 G351 S352 V378 I403 F405 F219 Y306 K308 G309 S310 V336 I361 F363 Q9NR97 29155428 RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE 5wyz B 2.30 BS01 7VF A 1 F261 Y348 I349 K350 G351 S352 V378 I403 F405 F219 Y306 I307 K308 G309 S310 V336 I361 F363 Q9NR97 29155428 RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE 5x3z A BS01 NUC B 1 K110 F112 G114 G115 V118 M139 M141 T146 R148 H149 R150 G151 F152 F154 E180 K182 K183 A184 Q185 K187 M190 S195 R197 R199 K6 F8 G10 G11 V14 M35 M37 T42 R44 H45 R46 G47 F48 F50 E76 K78 K79 A80 Q81 K83 M86 S91 R93 R95 Q61474 28753936 GSHMKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRS 5xdl A 2.70 BS01 8JC A 1 L718 G719 V726 A743 T790 L792 M793 P794 G796 C797 R841 L844 L23 G24 V31 A48 T93 L95 M96 P97 G99 C100 R144 L147 2.7.10.1 P00533 28881827 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKEEATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPEDMDDVVDADEYLI 5xkt A 1.80 BS01 GNP A 1 V16 G17 S18 G19 K20 T21 A22 D49 E104 N151 K152 D154 L155 N183 L184 K185 V11 G12 S13 G14 K15 T16 A17 D44 E99 N146 K147 D149 L150 N178 L179 K180 R4YE37 HPLRVGVGGPVGSGKTALLEALCKAMRDTWQLAVVTNDIYTKEDQRILTEAGTLAPERIVGVETGGCPHTAIREDASMNLAAVEALSEKFGNLDLIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITRSDFLVINKTDLAPYVGASLKVMASDTQRMRGDRPWTFTNLKQGDGLSTIIAFLEDKGMLG 5xkt A 1.80 BS02 NI A 1 T21 D49 E104 T16 D44 E99 R4YE37 HPLRVGVGGPVGSGKTALLEALCKAMRDTWQLAVVTNDIYTKEDQRILTEAGTLAPERIVGVETGGCPHTAIREDASMNLAAVEALSEKFGNLDLIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITRSDFLVINKTDLAPYVGASLKVMASDTQRMRGDRPWTFTNLKQGDGLSTIIAFLEDKGMLG 5xkt A 1.80 BS03 GNP B 1 A129 E130 G131 K133 K137 Y158 V159 A124 E125 G126 K128 K132 Y153 V154 R4YE37 HPLRVGVGGPVGSGKTALLEALCKAMRDTWQLAVVTNDIYTKEDQRILTEAGTLAPERIVGVETGGCPHTAIREDASMNLAAVEALSEKFGNLDLIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITRSDFLVINKTDLAPYVGASLKVMASDTQRMRGDRPWTFTNLKQGDGLSTIIAFLEDKGMLG 5xkt B 1.80 BS02 NI A 2 C72 H74 C67 H69 R4YE37 HPLRVGVGGPVGSGKTALLEALCKAMRDTWQLAVVTNDIYTKEDQRILTEAGTLAPERIVGVETGGCPHTAIREDASMNLAAVEALSEKFGNLDLIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITRSDFLVINKTDLAPYVGASLKVMASDTQRMRGDRPWTFTNLKQGDGLSTIIAFLEDKGMLG 5xmf A 2.10 BS01 III C 1 Y8 Y10 M46 R63 E64 K67 V68 N70 I74 D78 T81 L82 Y85 I96 R98 Y100 D117 S118 Y124 T144 K147 W148 E153 W157 Y160 T164 W168 Y172 Y7 Y9 M45 R62 E63 K66 V67 N69 I73 D77 T80 L81 Y84 I95 R97 Y99 D116 S117 Y123 T143 K146 W147 E152 W156 Y159 T163 W167 Y171 C6ZK72 GSHSLRYFYTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDAPNPRMEPRAPWVEQEGPEYWDRETRKVKNTAQIFRVDLNTLLRYYNQSESGSHNIQRMYGCDVEPDGRLLRGYNQDSYDGKDYIALNEDLRSWTAADTAAQITGRKWEEAGEAERWRNYLQGTCVEWLAKYLDMGKETLLRAESPNTRVTRHPISDREVTLRCWALGFYPAEITLTWQRDGQDHTQDAELVETRPAGDGTFQKWAAVVVSSGEEQRYTCHVQHEGLREPITLRWE 5xmm A 2.90 BS01 III C 1 Y8 Y10 M46 Y60 R63 E64 K67 V68 N70 I74 D78 T81 L82 Y85 I96 R98 Y100 D117 S118 Y124 T144 K147 W148 E153 R156 W157 Y160 S168 K171 Y172 Y7 Y9 M45 Y59 R62 E63 K66 V67 N69 I73 D77 T80 L81 Y84 I95 R97 Y99 D116 S117 Y123 T143 K146 W147 E152 R155 W156 Y159 S167 K170 Y171 C6ZK72 GSHSLRYFYTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDAPNPRMEPRAPWVEQEGPEYWDRETRKVKNTAQIFRVDLNTLLRYYNQSESGSHNIQRMYGCDVEPDGRLLRGYNQDSYDGKDYIALNEDLRSWTAADTAAQITGRKWEEAGEAERWRNYLQGTCVESLAKYLDMGKETLLRAESPNTRVTRHPISDREVTLRCWALGFYPAEITLTWQRDGQDHTQDAELVETRPAGDGTFQKWAAVVVSSGEEQRYTCHVQHEGLREPITLRWE 5xxl A 1.60 BS01 MG A 1 D699 V701 D672 V674 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVTGEITTGQAKSSDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTDYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLKL 5xxm A 1.70 BS02 LGC A 1 T59 F80 D110 F154 R168 K207 H208 M251 F254 D286 Y287 M317 E523 T35 F56 D86 F130 R144 K183 H184 M227 F230 D262 Y263 M293 E499 Q8A1U1 29131329 SPQDMDRFIDALMKKMTVEEKIGQLNLPVTGEITTGQAKSSDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTDYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLKLE 5xxm B 1.70 BS02 LGC B 1 T59 D110 F154 R168 K207 H208 M251 F254 D286 Y287 M317 E523 T32 D83 F127 R141 K180 H181 M224 F227 D259 Y260 M290 E496 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVTGEITTGQAKSSDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTDYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLK 5xxn A 2.05 BS02 BGC A 1 F254 Y287 E523 F219 Y252 E488 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVTGSSDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTNYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLKLEHHHHHH 5xxn A 2.05 BS03 BGC A 2 F80 D110 F154 R168 K207 H208 M251 F254 N286 M317 E523 F45 D75 F119 R133 K172 H173 M216 F219 N251 M282 E488 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVTGSSDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTNYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLKLEHHHHHH 5xxn A 2.05 BS04 GLC A 1 D426 S427 R428 T429 D442 D391 S392 R393 T394 D407 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVTGSSDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTNYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLKLEHHHHHH 5xxn A 2.05 BS05 BGC B 1 R622 F633 R587 F598 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVTGSSDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTNYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLKLEHHHHHH 5xxn B 2.05 BS04 BGC B 2 D110 F154 R168 K207 H208 M251 N286 M317 W435 E523 D70 F114 R128 K167 H168 M211 N246 M277 W395 E483 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTNYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLK 5xxo A 2.02 BS02 BGC A 1 T59 F80 D110 F154 R168 K207 H208 M251 F254 N286 M317 W435 E523 T32 F53 D83 F127 R141 K180 H181 M224 F227 N259 M290 W408 E496 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVTGEITTGQAKSSDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTNYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLKL 5xxo B 2.02 BS03 BGC B 2 N81 D110 W435 V437 N42 D71 W396 V398 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTNYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLK 5xxo B 2.02 BS04 BGC B 3 N81 D110 F154 R168 K207 H208 M251 F254 N286 M317 W435 E523 N42 D71 F115 R129 K168 H169 M212 F215 N247 M278 W396 E484 Q8A1U1 29131329 DMDRFIDALMKKMTVEEKIGQLNLPVDIAAKIKRGEVGGLFNLKGVEKIRDVQKQAVEQSRLGIPLLFGMDVIHGYETMFPIPLGLSCTWDMTAIEESARIAAIEASADGISWTFSPMVDISRDPRWGRVSEGSGEDPFLGAMIAEAMVLGYQGKDMQRNDEIMACVKHFALYGAGEGGRDYNTVDMSRQRMFNEYMLPYEAAVEAGVGSVMASFNEVDGVPATANKWLMTDVLRGQWGFNGFVVTNYTGISEMIDHGIGDLQTVSARAINAGVDMDMVSEGFVSTLKKSIQEGKVSMETLNTACRRILEAKYKLGLFDNPYKYCDLKRPARDIFTKAHRDAARRIAAESFVLLKNDNVTLRPGTPAEPLLPFNPKGNIAVIGPLADSRTNMPGTWSVAAVLDRCPSLVEGLKEMTAGKANILYAKGSNLISDASYEERATMFGRSLNRDNRTDEQLLNEALTVANQSDIIIAALGESSEMSGESSSRTDLNIPDVQQNLLKELLKTGKPVVLVLFTGRPLTLTWEQEHVPAILNVWFGGSEAAYAIGDALFGYVNPGGKLTMSFPKNVGQIPLYYAHKNTGRPLAQGKWFEKFRSNYLDVDNEPLYPFGYGLSYTTFSYGDIDLSRSTIDMTGELTAAVMVTNTGTWPGSEVVQLYIRDLVGSTTRPVKELKGFQKIFLEPGQSEIVRFKIAPEMLRYYNYDLQLVAEPGEFEVMIGTNSRDVKSARFTLK 5xyf A 2.20 BS01 III C 1 R52 R56 M59 F87 K106 E109 A110 T113 F114 E138 Y139 P142 F143 A146 R48 R52 M55 F83 K99 E102 A103 T106 F107 E131 Y132 P135 F136 A139 Q9BSI4 29160297 LVAGPAALRFAAAASWQVVRGRCVEHFPRVLEFLRSLRAVAPGLVRYRHHERLCMGLKAKVVVELILQGRPWAQVLKALNHHFPESGRDPKATKQDLRKILEAQETFYQQVKQLSEAPVDLASKLQELEQEYGEPFLAAMEKLLFEYLCQLEKALPTPQAQQLQDVLSWMQPGVSITSSLAWRQYGVDMGWL 5xyf A 2.20 BS02 III B 1 G8 A11 L12 F14 A18 Q21 V22 H30 R33 F37 S40 V44 A45 L158 A161 L162 P163 L170 L174 M177 S186 A188 G4 A7 L8 F10 A14 Q17 V18 H26 R29 F33 S36 V40 A41 L151 A154 L155 P156 L163 L167 M170 S179 A181 Q9BSI4 29160297 LVAGPAALRFAAAASWQVVRGRCVEHFPRVLEFLRSLRAVAPGLVRYRHHERLCMGLKAKVVVELILQGRPWAQVLKALNHHFPESGRDPKATKQDLRKILEAQETFYQQVKQLSEAPVDLASKLQELEQEYGEPFLAAMEKLLFEYLCQLEKALPTPQAQQLQDVLSWMQPGVSITSSLAWRQYGVDMGWL 5xzr A 2.80 BS01 8J6 A 1 T108 E110 R111 F113 H114 N217 T218 E249 E250 T253 L254 P491 K492 T108 E110 R111 F113 H114 N217 T218 E246 E247 T250 L251 P476 K477 3.1.3.48 Q06124 29155585 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAALVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAEKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQK 6au5 B 2.48 BS01 III E 1 P9 Q39 P41 T90 A91 I92 Y94 Q111 G112 L114 E154 P173 P9 Q39 P41 T90 A91 I92 Y94 Q111 G112 L114 E154 P173 S6B291 29199990 QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 6axp A 2.48 BS01 III E 1 Q38 R39 T40 N41 G42 A84 D85 Y87 A100 G101 K103 Q38 R39 T40 N41 G42 A84 D85 Y87 A100 G101 K103 P01834 29199990 DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG 6axp B 2.48 BS01 III E 1 Q39 S40 P41 T90 A91 I92 Y94 Q111 G112 L114 E154 P155 P173 Q39 S40 P41 T90 A91 I92 Y94 Q111 G112 L114 E154 P155 P173 S6B291 29199990 QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 6axp C 2.48 BS01 III F 1 R39 T40 N41 G42 A84 D85 Y87 K103 E165 R39 T40 N41 G42 A84 D85 Y87 K103 E165 P01834 29199990 DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG 6ayn A 2.48 BS01 III F 1 V9 I10 Q38 R39 T40 N41 G42 A84 D85 Y87 G101 K103 E165 V9 I10 Q38 R39 T40 N41 G42 A84 D85 Y87 G101 K103 E165 P01834 29199990 DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG 6ayn B 2.48 BS01 III F 1 Q39 S40 P41 T90 I92 Q111 G112 E154 P173 Q39 S40 P41 T90 I92 Q111 G112 E154 P173 S6B291 29199990 QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 6ayn C 2.48 BS01 III E 1 Q38 R39 T40 N41 G42 A84 D85 Y87 G101 K103 E165 Q38 R39 T40 N41 G42 A84 D85 Y87 G101 K103 E165 P01834 29199990 DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG 6ayn D 2.48 BS01 III E 1 Q39 S40 P41 T90 A91 I92 Y94 Q111 G112 E154 P173 Q39 S40 P41 T90 A91 I92 Y94 Q111 G112 E154 P173 S6B291 29199990 QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 6azk B 2.48 BS01 III E 1 P9 Q39 P41 T90 A91 I92 Y94 Q111 G112 T113 L114 E154 P155 P173 P9 Q39 P41 T90 A91 I92 Y94 Q111 G112 T113 L114 E154 P155 P173 S6B291 29199990 QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP 6azk C 2.48 BS01 III F 1 V9 Q38 R39 T40 N41 G42 S43 A84 D85 Y87 G101 K103 E165 V9 Q38 R39 T40 N41 G42 S43 A84 D85 Y87 G101 K103 E165 P01834 29199990 DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG 6azl D 2.48 BS01 III F 1 Q39 P41 T90 A91 I92 Y94 Q111 E154 P155 P173 Q39 P41 T90 A91 I92 Y94 Q111 E149 P150 P168 S6B291 29199990 QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 6azm A 1.60 BS01 III E 1 Y27D Y32 W50 Y92 Y31 Y38 W56 Y98 DIVMTQSPDSLAVSLGERATINCKSSQSVLYSSNNKNYLAWYQQKPGQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYSTPITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6azm B 1.60 BS01 III E 1 S100 S100A P100B R100E S104 S105 P106 R109 EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDPGGDSSPAGRTWFDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 6azm D 1.60 BS01 III F 1 S100 S100A R100E T100F S104 S105 R109 T110 EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDPGGDSSPAGRTWFDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 6b04 A 1.83 BS01 C6J A 1 D147 D151 R156 Q215 K244 T245 Y248 Q284 D287 K301 D91 D95 R100 Q159 K188 T189 Y192 Q228 D231 K245 2.5.1.- Q1XAB1 29183817 TKKESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMERRQKSDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b04 A 1.83 BS02 MG A 1 D147 D151 D91 D95 2.5.1.- Q1XAB1 29183817 TKKESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMERRQKSDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b06 A 2.60 BS01 C6J A 1 D147 D151 R156 K244 T245 Q284 D287 K301 D91 D95 R100 K185 T186 Q225 D228 K242 2.5.1.- Q1XAB1 29183817 TKKESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMQKSDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b06 A 2.60 BS04 MG A 3 D287 D291 D305 D228 D232 D246 2.5.1.- Q1XAB1 29183817 TKKESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMQKSDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b06 A 2.60 BS05 IPE A 1 G100 K101 R104 Q140 R157 Y248 D287 G44 K45 R48 Q84 R101 Y189 D228 2.5.1.- Q1XAB1 29183817 TKKESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMQKSDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b06 B 2.60 BS01 C6J B 1 D147 D151 R156 Q215 K244 T245 Q284 D287 K301 D90 D94 R99 Q158 K185 T186 Q225 D228 K242 2.5.1.- Q1XAB1 29183817 KKESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMRQKSDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b06 B 2.60 BS02 MG B 1 D147 D151 Q215 D90 D94 Q158 2.5.1.- Q1XAB1 29183817 KKESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMRQKSDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b06 C 2.60 BS01 C6J C 1 L143 D147 D151 R156 K244 T245 Y248 Q284 D287 K301 L84 D88 D92 R97 K181 T182 Y185 Q221 D224 K238 2.5.1.- Q1XAB1 29183817 ESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMESDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b06 C 2.60 BS04 IPE C 1 K101 R104 Q140 Y248 F283 Q284 D287 K42 R45 Q81 Y185 F220 Q221 D224 2.5.1.- Q1XAB1 29183817 ESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMESDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b07 A 1.98 BS01 C6M A 1 R104 D147 D151 R156 Q215 K244 T245 Y248 F283 Q284 D287 K301 R48 D91 D95 R100 Q159 K188 T189 Y192 F227 Q228 D231 K245 2.5.1.- Q1XAB1 29183817 TKKESFEDVLPSILNTITTNSELTEVPEVANWLKKVLEYNLAGGKKARGLTTLFAYEMLEKPENITEETIYLAKTLGWCVEILQGFLVMLDDIMDGSTTRRGVPCWYQLPEVGLAAVNDSSLMFSSIFYVLHAHFADKKIYTNLVELFNESLMHTSIGQHLDVTMERRQKSDYSLFTIERYNAIVKYKTAYYTYQLPVCLGMLLANISDPVLHQKAEDMCLEIGKFFQIQDDYIDCYGDESLTGKMGTDIQEAKCSWLAVMALQRCSASQKIVFTTCYGSKEPAHIERIKELYKQLQLPELYAQEETRMYESLIKQAHGLPSELSPALFVRLIHMIYKRNH 6b2w A 2.50 BS01 AG2 A 1 W79 D82 W104 F108 D195 T196 H199 Q309 N310 S315 W87 D90 W112 F116 D203 T204 H207 Q317 N318 S323 Q0P9V0 29190068 ENLYFQGHMIKSIPEWSEQEYLMLSLPHEKSDWNPYLEEILQSYKEFVKVVSEFQKVLLIAPKQSDFENFKDIKNVEFFKCDTNDTWIRDFGAIDIVENGRLKALDFTFNAWGNKFQSELDNAVNSKLFKEKFKEELKKVDFILEGGSIDFNGEGVMLTSSHCLLNENRNSHLNKTQIDTKLKEIFGLKQIIWLENGFIKGDDTDHHIDTLARFIDKNTIAHCICEDEEDEHYLPLQKMKEELKKTGFDLLELPIPKPLYYEERRLGATYANFVFINNALIVPFYKDKNDEIIAKRLSKALPNHKIIGVDARVFLRQNGSLHSSCQNRFKGLR 6b2w B 2.50 BS01 AG2 B 1 D77 W79 D82 W104 F108 D195 T196 Q309 N310 S315 D85 W87 D90 W112 F116 D203 T204 Q317 N318 S323 Q0P9V0 29190068 ENLYFQGHMIKSIPEWSEQEYLMLSLPHEKSDWNPYLEEILQSYKEFVKVVSEFQKVLLIAPKQSDFENFKDIKNVEFFKCDTNDTWIRDFGAIDIVENGRLKALDFTFNAWGNKFQSELDNAVNSKLFKEKFKEELKKVDFILEGGSIDFNGEGVMLTSSHCLLNENRNSHLNKTQIDTKLKEIFGLKQIIWLENGFIKGDDTDHHIDTLARFIDKNTIAHCICEDEEDEHYLPLQKMKEELKKTGFDLLELPIPKPLYYEERRLGATYANFVFINNALIVPFYKDKNDEIIAKRLSKALPNHKIIGVDARVFLRQNGSLHSSCQNRFKGLR 6b82 A 3.03 BS01 HEM A 1 R109 A126 W134 R138 I310 A313 T317 T318 T321 V377 L381 H384 P445 F446 R451 C453 L454 G455 A459 R71 A88 W96 R100 I268 A271 T275 T276 T279 V335 L339 H342 P403 F404 R409 C411 L412 G413 A417 A2ATX9 RSPPSLPSLPIIGSLMSLVSDSPPHIFFQDLQKKYGDLYSLMMGSHKLLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKFHRKMVHGALCMFGEGSVSIEKIICREASSMCEVLTESQNLGPELTRAVTNVVCALCFNSSYKRGDAEFESMLQYSQGIVDTVAKDSLVDIFPWLQIFPNKDLRILRQCISIRDKLLQKKYEEHKVTYSDNVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGEIFGAGVETTTTTLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATICEVMRIRPVSPLLIPHVALQDSSVGEYTVQKGTRVVINMWSLHHDEKEWKNPELFDPGRFLNEEGDGLCCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFGVVLQPKKFKVVAKVR 6b82 A 3.03 BS02 AER A 1 A126 S215 I218 V219 E309 G312 T317 V377 S378 A88 S173 I176 V177 E267 G270 T275 V335 S336 A2ATX9 RSPPSLPSLPIIGSLMSLVSDSPPHIFFQDLQKKYGDLYSLMMGSHKLLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKFHRKMVHGALCMFGEGSVSIEKIICREASSMCEVLTESQNLGPELTRAVTNVVCALCFNSSYKRGDAEFESMLQYSQGIVDTVAKDSLVDIFPWLQIFPNKDLRILRQCISIRDKLLQKKYEEHKVTYSDNVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGEIFGAGVETTTTTLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATICEVMRIRPVSPLLIPHVALQDSSVGEYTVQKGTRVVINMWSLHHDEKEWKNPELFDPGRFLNEEGDGLCCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFGVVLQPKKFKVVAKVR 6b82 B 3.03 BS02 AER B 1 S215 V219 E309 G312 T317 V377 V493 S177 V181 E271 G274 T279 V339 V455 A2ATX9 RSPPSLPSLPIIGSLMSLVSDSPPHIFFQDLQKKYGDLYSLMMGSHKLLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKFHRKMVHGALCMFGEGSVSIEKIICREASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFNSSYKRGDAEFESMLQYSQGIVDTVAKDSLVDIFPWLQIFPNKDLRILRQCISIRDKLLQKKYEEHKVTYSDNVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGEIFGAGVETTTTTLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATICEVMRIRPVSPLLIPHVALQDSSVGEYTVQKGTRVVINMWSLHHDEKEWKNPELFDPGRFLNEEGDGLCCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFGVVLQPKKFKVVAKVRA 6bc0 F 2.20 BS02 GSP F 1 D13 G14 A15 C16 G17 K18 T19 C20 F30 Y34 P36 T37 A61 G62 Q63 K118 D120 L121 S160 A161 K162 D11 G12 A13 C14 G15 K16 T17 C18 F28 Y32 P34 T35 A59 G60 Q61 K116 D118 L119 S158 A159 K160 P61586 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQA 6bc1 A 2.90 BS01 GSP A 1 D11 G12 A13 G15 K16 T17 C18 F28 Y32 P34 T35 T58 G60 K116 D118 L119 S158 A159 L160 D11 G12 A13 G15 K16 T17 C18 F28 Y32 P34 T35 T58 G60 K116 D118 L119 S158 A159 L160 P63000 PQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 6bc1 B 2.90 BS01 GSP B 1 A13 G15 K16 T17 C18 F28 Y32 I33 P34 T35 D57 T58 G60 K116 D118 L119 A159 L160 A13 G15 K16 T17 C18 F28 Y32 I33 P34 T35 D57 T58 G60 K116 D118 L119 A159 L160 P63000 PQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 6bca F 2.00 BS02 GSP F 1 D13 G14 A15 C16 G17 K18 T19 C20 F30 Y34 V35 P36 T37 G62 K118 D120 L121 S160 A161 K162 D11 G12 A13 C14 G15 K16 T17 C18 F28 Y32 V33 P34 T35 G60 K116 D118 L119 S158 A159 K160 P61586 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQA 6bco B 2.88 BS01 ATP B 1 H160 R172 W214 R215 L226 D227 Y228 H106 R118 W160 R161 L172 D173 Y174 Q7TN37 PKIFRKKVCTTFITTEKPTDAYGDLDFTYSGRKHSNFLRLSDRTDPATVYSLVTRSWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQTASTGSSKVVAMGVAPWGVVRNRDMLINPKGSFPARYRWRGDPEDGVEFPLDYNYSAFFLVDDGTYGRLGGENRFRLRFESYVAQQKTGVGGTGIDIPVLLLLIDGDEKMLKRIEDATQAQLPCLLVAGSGGAADCLVETLEEARDRIRRYFPKGDPEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLRALVKACGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPVRLAQLYSAVSPNSLIRNLLDQASHAPNVGQVLRTLLGETCAPRYAPWSDLLIWALLLNRAQMAIYFWEKGSNSVASALGACLLLRVMARLESEAEEAARRKDLAATFESMSVDLFGECYHNSEERAARLLLRRCPLWGEATCLQLAMQADARAFFAQDGVQSLLTQKWWGEMDSTTPIWALLLAFFCPPLIYTNLIVFRKSKRWSDFWGAPVTAFLGNVVSYLLFLLLFAHVLLVDFQPTKPSVSELLLYFWAFTLLCEELRQGLGLRHRLHLYLSDTWNQCDLLALTCFLLGVGCRLTPGLFDLGRTVLCLDFMIFTLRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLCVWLVAYGVATEGILRPQDRSLPSILRRVFYRPYLQIFGQIPQEEMDVALMIPGNCSMERGSWAHPEGPVAGSCVSQYANWLVVLLLIVFLLVANILLLNLLIAMFSYTFSKVHGNSDLYWKAQRYSLIREFHSRPALAPPLIIISHVRLLIKWLRRLSKEAERKLLTWESVHKENFLLAQARDKRDSDSERLKRTSQKVDTALKQLG 6bco B 2.88 BS02 ATP A 1 R422 S423 G449 R355 S356 G382 Q7TN37 PKIFRKKVCTTFITTEKPTDAYGDLDFTYSGRKHSNFLRLSDRTDPATVYSLVTRSWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQTASTGSSKVVAMGVAPWGVVRNRDMLINPKGSFPARYRWRGDPEDGVEFPLDYNYSAFFLVDDGTYGRLGGENRFRLRFESYVAQQKTGVGGTGIDIPVLLLLIDGDEKMLKRIEDATQAQLPCLLVAGSGGAADCLVETLEEARDRIRRYFPKGDPEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLRALVKACGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPVRLAQLYSAVSPNSLIRNLLDQASHAPNVGQVLRTLLGETCAPRYAPWSDLLIWALLLNRAQMAIYFWEKGSNSVASALGACLLLRVMARLESEAEEAARRKDLAATFESMSVDLFGECYHNSEERAARLLLRRCPLWGEATCLQLAMQADARAFFAQDGVQSLLTQKWWGEMDSTTPIWALLLAFFCPPLIYTNLIVFRKSKRWSDFWGAPVTAFLGNVVSYLLFLLLFAHVLLVDFQPTKPSVSELLLYFWAFTLLCEELRQGLGLRHRLHLYLSDTWNQCDLLALTCFLLGVGCRLTPGLFDLGRTVLCLDFMIFTLRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLCVWLVAYGVATEGILRPQDRSLPSILRRVFYRPYLQIFGQIPQEEMDVALMIPGNCSMERGSWAHPEGPVAGSCVSQYANWLVVLLLIVFLLVANILLLNLLIAMFSYTFSKVHGNSDLYWKAQRYSLIREFHSRPALAPPLIIISHVRLLIKWLRRLSKEAERKLLTWESVHKENFLLAQARDKRDSDSERLKRTSQKVDTALKQLG 6bcq B 3.25 BS02 ATP A 1 R422 S423 H448 G449 R355 S356 H381 G382 Q7TN37 PKIFRKKVCTTFITTEKPTDAYGDLDFTYSGRKHSNFLRLSDRTDPATVYSLVTRSWGFRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVRDHQTASTGSSKVVAMGVAPWGVVRNRDMLINPKGSFPARYRWRGDPEDGVEFPLDYNYSAFFLVDDGTYGRLGGENRFRLRFESYVAQQKTGVGGTGIDIPVLLLLIDGDEKMLKRIEDATQAQLPCLLVAGSGGAADCLVETLEEARDRIRRYFPKGDPEVLQAQVERIMTRKELLTVYSSEDGSEEFETIVLRALVKACGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHGLSLGHFLTPVRLAQLYSAVSPNSLIRNLLDQASHAPNVGQVLRTLLGETCAPRYAPWSDLLIWALLLNRAQMAIYFWEKGSNSVASALGACLLLRVMARLESEAEEAARRKDLAATFESMSVDLFGECYHNSEERAARLLLRRCPLWGEATCLQLAMQADARAFFAQDGVQSLLTQKWWGEMDSTTPIWALLLAFFCPPLIYTNLIVFRKSKRWSDFWGAPVTAFLGNVVSYLLFLLLFAHVLLVDFQPTKPSVSELLLYFWAFTLLCEELRQGLGLRHRLHLYLSDTWNQCDLLALTCFLLGVGCRLTPGLFDLGRTVLCLDFMIFTLRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLCVWLVAYGVATEGILRPQDRSLPSILRRVFYRPYLQIFGQIPQEEMDVALMIPGNCSMERGSWAHPEGPVAGSCVSQYANWLVVLLLIVFLLVANILLLNLLIAMFSYTFSKVHGNSDLYWKAQRYSLIREFHSRPALAPPLIIISHVRLLIKWLRRLSKEAERKLLTWESVHKENFLLAQARDKRDSDSERLKRTSQKVDTALKQLGQIREYDRRLRGLEREVQHCSRVLTWMAEALS 6bcz A 2.23 BS01 HEM A 1 R105 I118 S119 W126 R130 F137 F302 A305 G306 V313 I369 A370 L373 R375 P434 F435 G436 S437 R440 N441 C442 I443 G444 F447 A448 M452 R79 I92 S93 W100 R104 F111 F267 A270 G271 V278 I334 A335 L338 R340 P399 F400 G401 S402 R405 N406 C407 I408 G409 F412 A413 M417 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDVDFLQLMIDSQNSSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6bcz A 2.23 BS02 D7Y A 1 F108 S119 I120 R212 F304 A305 T309 A370 R372 F82 S93 I94 R186 F269 A270 T274 A335 R337 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDVDFLQLMIDSQNSSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6bd5 A 2.50 BS02 D7M A 1 F108 S119 I120 I301 F304 A305 T309 R372 E374 F80 S91 I92 I262 F265 A266 T270 R333 E335 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDVDFLQLMIDSQNSKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6bd6 A 2.50 BS02 80K A 1 R105 F108 S119 I120 F213 F241 I301 F304 A305 T309 R78 F81 S92 I93 F186 F214 I262 F265 A266 T270 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDVDFLQLMIDSQNKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6bd7 A 2.42 BS02 D7J A 1 R105 F108 S119 I120 R212 F213 F215 F304 A305 T309 I369 A370 R372 E374 R78 F81 S92 I93 R185 F186 F188 F269 A270 T274 I334 A335 R337 E339 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDRVDFLQLMIDSQNSSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 6bd8 A 2.38 BS02 D81 A 1 R105 F108 S119 I120 L211 R212 F213 F215 F241 I301 F304 A305 T309 R77 F80 S91 I92 L183 R184 F185 F187 F213 I262 F265 A266 T270 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDVDFLQLMIDSQNSKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6bdh A 2.25 BS01 HEM A 1 R105 I118 S119 W126 R130 F302 A305 G306 T309 V313 I369 A370 L373 R375 P434 F435 G436 S437 R440 N441 C442 I443 G444 A448 M452 R78 I91 S92 W99 R103 F245 A248 G249 T252 V256 I312 A313 L316 R318 P377 F378 G379 S380 R383 N384 C385 I386 G387 A391 M395 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESDFLQLMIDSQNKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6bdh A 2.25 BS02 DEV A 1 R105 M114 S119 F241 I300 I301 F304 A305 T309 I369 L482 R78 M87 S92 F201 I243 I244 F247 A248 T252 I312 L425 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESDFLQLMIDSQNKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6bdi A 2.57 BS02 DEJ A 1 R105 S119 R212 F213 F215 I301 F304 A305 T309 I369 A370 R372 E374 R79 S93 R186 F187 F189 I266 F269 A270 T274 I334 A335 R337 E339 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDRVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 6bdm A 2.60 BS01 HEM A 1 R105 I118 S119 W126 R130 I301 F302 G306 T309 I369 A370 L373 R375 P434 F435 G436 S437 R440 N441 C442 I443 G444 F447 A448 M452 R78 I91 S92 W99 R103 I261 F262 G266 T269 I329 A330 L333 R335 P394 F395 G396 S397 R400 N401 C402 I403 G404 F407 A408 M412 1.14.13.-,1.14.13.157,1.14.13.32,1.14.14.1,1.14.13.67,1.14.13.97 P08684 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6bgf A 2.25 BS01 CYS A 1 Y58 R60 L75 H86 H88 H140 V142 H155 Y157 Y54 R56 L71 H82 H84 H136 V138 H151 Y153 1.13.11.20 Q16878 EVLKPRTLADLIRILHQLFAGDEVNVEEVQAIMEAYESDPTEWAMYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGNLKETLFAWPDKKSNEMVKKSERVLRENQCAYINDSVGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTPNA 6bn5 A 2.22 BS01 DZJ A 1 R111 N217 E250 T253 L254 Q257 P491 K492 Q495 M496 R87 N175 E197 T200 L201 Q204 P418 K419 Q422 M423 3.1.3.48 Q06124 29089257 WFHPNITGVEAENLLLTRGVDGSFLARPSDFTLSVRAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHIELKYPLNCADPTSERWFHGHLSGKEAEKLLTHGSFLVREPGDFVLSVRTGDSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPNTTRINAAIESRVRELSQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPSDHTRVVLHSDYINANIIMPKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHY 6bo7 A 2.86 BS02 YPG A 1 K77 G78 R112 E144 I146 D148 T149 G150 K151 T152 K176 A196 F197 V198 L203 D204 R210 K79 G80 R114 E136 I138 D140 T141 G142 K143 T144 K168 A188 F189 V190 L195 D196 R202 2.4.2.8 A0A1G4HBT9 29161011 HHHKIPNNPGAGENALEPIYIKDDDGYDIDTFLIPDHYKNYITKVLIPNGVLKNRIEKLAFDIKQVYRNEEFHVICLLKGSRGFFSALLKYLNRIHNYSSTESPKHLYVEHYVRVKIEIVSEDLSCLKDKHVLIVEDIIDTGKTLLKFCEYLKKFEVKTIAITCLFIKRTPLWNGFKADFVGFSIPDAFVVGYSLDYNEKFRDLDHLCLVNDEGIKKFRT 6bo7 C 2.86 BS03 YPG C 1 K77 R112 E144 I146 I147 D148 T149 G150 K151 T152 K176 A196 F197 V198 D204 R210 K77 R112 E135 I137 I138 D139 T140 G141 K142 T143 K167 A187 F188 V189 D195 R201 2.4.2.8 A0A1G4HBT9 29161011 HKIPNNPGAGENALEPIYIKDDDGYDIDTFLIPDHYKNYITKVLIPNGVLKNRIEKLAFDIKQVYRNEEFHVICLLKGSRGFFSALLKYLNRIHNYSSTESPKHLYVEHYVRVKSIEIVSEDLSCLKDKHVLIVEDIIDTGKTLLKFCEYLKKFEVKTIAITCLFIKRTPLWNGFKADFVGFSIPDAFVVGYSLDYNEKFRDLDHLCLVNDEGIKKFRT 6bo7 D 2.86 BS03 YPG D 1 K77 G78 R112 E144 I146 D148 T149 G150 T152 K176 F197 V198 L203 D204 R210 K76 G77 R111 E134 I136 D138 T139 G140 T142 K166 F187 V188 L193 D194 R200 2.4.2.8 A0A1G4HBT9 29161011 KIPNNPGAGENALEPIYIKDDDGYDIDTFLIPDHYKNYITKVLIPNGVLKNRIEKLAFDIKQVYRNEEFHVICLLKGSRGFFSALLKYLNRIHNYSSTESPKHLYVEHYVRVKSIEIVSEDLSCLKDKHVLIVEDIIDTGKTLLKFCEYLKKFEVKTIAITCLFIKRTPLWNGFKADFVGFSIPDAFVVGYSLDYNEKFRDLDHLCLVNDEGIKKFRT 6bo7 F 2.86 BS03 YPG F 1 L76 K77 E144 I146 D148 T149 G150 K151 T152 K176 A196 F197 V198 L203 D204 L77 K78 E136 I138 D140 T141 G142 K143 T144 K168 A188 F189 V190 L195 D196 2.4.2.8 A0A1G4HBT9 29161011 HHKIPNNPGAGENALEPIYIKDDDGYDIDTFLIPDHYKNYITKVLIPNGVLKNRIEKLAFDIKQVYRNEEFHVICLLKGSRGFFSALLKYLNRIHNYSSTESPKHLYVEHYVRVKSIEIVSEDLSCLKDKHVLIVEDIIDTGKTLLKFCEYLKKFEVKTIAITCLFIKRTPLWNGFKADFVGFSIPDAFVVGYSLDYNEKFRDLDHLCLVNDEGIKKFRT 6bo7 J 2.86 BS02 YPG J 1 K77 R112 E144 I146 D148 T149 G150 T152 K176 A196 F197 V198 D204 R210 K76 R111 E134 I136 D138 T139 G140 T142 K166 A186 F187 V188 D194 R200 2.4.2.8 A0A1G4HBT9 29161011 KIPNNPGAGENALEPIYIKDDDGYDIDTFLIPDHYKNYITKVLIPNGVLKNRIEKLAFDIKQVYRNEEFHVICLLKGSRGFFSALLKYLNRIHNYSSTESPKHLYVEHYVRVKSIEIVSEDLSCLKDKHVLIVEDIIDTGKTLLKFCEYLKKFEVKTIAITCLFIKRTPLWNGFKADFVGFSIPDAFVVGYSLDYNEKFRDLDHLCLVNDEGIKKFRT 6bq1 A 3.60 BS01 E4S A 1 S1797 K1850 I1896 C1898 I1899 D1901 S1904 Q1907 N1962 M1964 I1974 S1273 K1290 I1336 C1338 I1339 D1341 S1344 Q1347 N1396 M1398 I1408 2.7.1.67 P42356 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGMMQCVIAVADKVFDAFLNMMADKAKTKENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLSERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFDLNKMMVQDLHSALDRSHPQHYTQAMFKLTAMLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKDGVEVPFMREMAGAWHMTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYPMQSAAKAPYLAKFWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSN 6bq1 E 3.60 BS01 E4S E 1 S1797 K1850 Y1884 I1896 E1897 C1898 I1899 S1904 Q1907 N1962 M1964 I1974 S1274 K1291 Y1325 I1337 E1338 C1339 I1340 S1345 Q1348 N1397 M1399 I1409 2.7.1.67 P42356 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGMMQCVIAVADKVFDAFLNMMADKAKTKENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLSERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFDLNKMMVQDLHSALDRSHPQHYTQAMFKLTAMLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKDGVEVPFMREMAGAWHMTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYPMQSAAKAPYLAKFWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSN 6bql A 2.00 BS01 BI9 A 1 I171 G172 Y176 A192 F267 E268 L269 V270 N271 G273 N317 L319 I13 G14 Y18 A34 F97 E98 L99 V100 N101 G103 N147 L149 2.7.11.17 Q96RR4 SMQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTR 6bqp A 1.95 BS01 6T2 A 1 I171 G172 G174 V179 A192 F267 E268 L269 V270 N271 Q272 G273 P274 S316 N317 L319 A329 D330 I12 G13 G15 V20 A33 F82 E83 L84 V85 N86 Q87 G88 P89 S131 N132 L134 A144 D145 2.7.11.17 Q96RR4 MQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTR 6bqq A 1.80 BS01 R78 A 1 I171 G172 V179 A192 V249 F267 E268 L269 V270 N271 L319 I13 G14 V21 A34 V73 F91 E92 L93 V94 N95 L143 2.7.11.17 Q96RR4 SMQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTR 6bqz A 2.30 BS01 TYR A 1 K46 G48 L80 Q182 D185 Q200 K39 G41 L73 Q170 D173 Q188 6.1.1.1 A0A086HYS2 HHHLPAEEQLALIQRGTHEIISEEDLLKKLKENRPLKIKAGFDPTAPDLHLGHTVLINKLKTFQDLGHEVTFLIGDYTAMIGDPTRPPLSREQVEANAKTYQEQVFKILDPNKTKVRFNSEWFNQKSAADLIQLASQQTVSRMLERDDFTKRYNNHQPIAIHEFLYPLVQGYDSIALEADVELGGTDQTFNLLMGRTLQSRYGQESQVCITVPIL 6bqz A 2.30 BS02 MG A 1 R129 F130 E133 R117 F118 E121 6.1.1.1 A0A086HYS2 HHHLPAEEQLALIQRGTHEIISEEDLLKKLKENRPLKIKAGFDPTAPDLHLGHTVLINKLKTFQDLGHEVTFLIGDYTAMIGDPTRPPLSREQVEANAKTYQEQVFKILDPNKTKVRFNSEWFNQKSAADLIQLASQQTVSRMLERDDFTKRYNNHQPIAIHEFLYPLVQGYDSIALEADVELGGTDQTFNLLMGRTLQSRYGQESQVCITVPIL 6brc A 2.20 BS01 E5J A 1 G172 V179 A192 F267 E268 L269 V270 N271 G273 P274 L319 A329 G14 V21 A34 F84 E85 L86 V87 N88 G90 P91 L136 A146 2.7.11.17 Q96RR4 SMQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTR 6brd A 3.32 BS02 RFP A 1 Q43 H46 V69 F74 V93 L176 M192 R196 R201 A204 M205 R213 V215 T285 G286 M342 Q43 H46 V69 F74 V93 L176 M192 R196 R201 A204 M205 R213 V215 T285 G286 M342 F2R776 MFDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQGLHVRSIEVMAQRGLLERFLERGHTVAVGGFFAGLATSWPERLDTAHSYVLAVPQVITEQLLAEHATALGAEIRRGRALVGLRQDEDGVTVDLADGEQLRARYVVGCDGGRSTVRKLLGVAFPGEPSRVETLLGEMEMTASQEELTSVMTEVRKTQQRFGAMPLGDGVFRVVVPAEGVAEDRTASPTLDEFKQQLRAHAGTDFGVHSPRWLSRFGDATRQAERYRVDRVFLAGDAAHIHPPTGGQGLNLGIQDAFNLGWKLAAEVDGWAPEGLLDTYHAERHPVATEVLDNTRAQIQLMSTEPGPQAVRRLMAELVEFENVNRYLIEKITAISVRYDVGEGHELLGRRMRDLALKHGRLYERMHEGRGLLLDQTGRLSVAGWEDRVDHVVEVSEELDVPAVLLRPDGHVVWAGEDQQELLTRMPAWFGAAT 6brd B 3.32 BS01 FAD B 1 V7 G8 G10 P11 T12 L30 E31 K32 R41 A42 Q43 Q98 R120 L122 C150 D151 G152 T156 L176 F257 D277 P284 G287 G289 L290 N291 V7 G8 G10 P11 T12 L30 E31 K32 R41 A42 Q43 Q98 R120 L122 C150 D151 G152 T156 L176 F257 D277 P284 G287 G289 L290 N291 F2R776 MFDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQGLHVRSIEVMAQRGLLERFLERGHTVAVGGFFAGLATSWPERLDTAHSYVLAVPQVITEQLLAEHATALGAEIRRGRALVGLRQDEDGVTVDLADGEQLRARYVVGCDGGRSTVRKLLGVAFPGEPSRVETLLGEMEMTASQEELTSVMTEVRKTQQRFGAMPLGDGVFRVVVPAEGVAEDRTASPTLDEFKQQLRAHAGTDFGVHSPRWLSRFGDATRQAERYRVDRVFLAGDAAHIHPPTGGQGLNLGIQDAFNLGWKLAAEVDGWAPEGLLDTYHAERHPVATEVLDNTRAQIQLMSTEPGPQAVRRLMAELVEFENVNRYLIEKITAISVRYDVGEGHELLGRRMRDLALKHGRLYERMHEGRGLLLDQTGRLSVAGWEDRVDHVVEVSEELDVPAVLLRPDGHVVWAGEDQQELLTRMPAWFGAAT 6brd B 3.32 BS02 RFP B 1 Q43 H46 F74 V93 L176 M192 R196 G203 M205 R213 V215 P284 T285 G286 M342 Q43 H46 F74 V93 L176 M192 R196 G203 M205 R213 V215 P284 T285 G286 M342 F2R776 MFDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQGLHVRSIEVMAQRGLLERFLERGHTVAVGGFFAGLATSWPERLDTAHSYVLAVPQVITEQLLAEHATALGAEIRRGRALVGLRQDEDGVTVDLADGEQLRARYVVGCDGGRSTVRKLLGVAFPGEPSRVETLLGEMEMTASQEELTSVMTEVRKTQQRFGAMPLGDGVFRVVVPAEGVAEDRTASPTLDEFKQQLRAHAGTDFGVHSPRWLSRFGDATRQAERYRVDRVFLAGDAAHIHPPTGGQGLNLGIQDAFNLGWKLAAEVDGWAPEGLLDTYHAERHPVATEVLDNTRAQIQLMSTEPGPQAVRRLMAELVEFENVNRYLIEKITAISVRYDVGEGHELLGRRMRDLALKHGRLYERMHEGRGLLLDQTGRLSVAGWEDRVDHVVEVSEELDVPAVLLRPDGHVVWAGEDQQELLTRMPAWFGAAT 6brd C 3.32 BS01 FAD C 1 V7 G8 G10 P11 T12 L30 E31 K32 E33 R41 A42 Q43 Q98 R120 L122 C150 D151 G152 T156 L176 F257 G276 D277 P284 G287 Q288 G289 L290 N291 V7 G8 G10 P11 T12 L30 E31 K32 E33 R41 A42 Q43 Q98 R120 L122 C150 D151 G152 T156 L176 F251 G270 D271 P278 G281 Q282 G283 L284 N285 F2R776 MFDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQGLHVRSIEVMAQRGLLERFLERGHTVAVGGFFAGLATSWPERLDTAHSYVLAVPQVITEQLLAEHATALGAEIRRGRALVGLRQDEDGVTVDLADGEQLRARYVVGCDGGRSTVRKLLGVAFPGEPSRVETLLGEMASQEELTSVMTEVRKTQQRFGAMPGVFRVVVPAEGVAEDRTASPTLDEFKQQLRAHAGTDFGVHSPRWLSRFGDATRQAERYRVDRVFLAGDAAHIHPPTGGQGLNLGIQDAFNLGWKLAAEVDGWAPEGLLDTYHAERHPVATEVLDNTRAQIQLMSTEPGPQAVRRLMAELVEFENVNRYLIEKITAISVRYDVGEGHELLGRRMRDLALKHGRLYERMHEGRGLLLDQTGRLSVAGWEDRVDHVVEVSEELDVPAVLLRPDGHVVWAGEDQQELLTRMPAWFGAAT 6brd C 3.32 BS02 RFP C 1 Q43 V69 V71 F74 V93 M192 R196 G203 A204 M205 R213 V215 P284 T285 G286 Q43 V69 V71 F74 V93 M189 R193 G200 A201 M202 R207 V209 P278 T279 G280 F2R776 MFDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQGLHVRSIEVMAQRGLLERFLERGHTVAVGGFFAGLATSWPERLDTAHSYVLAVPQVITEQLLAEHATALGAEIRRGRALVGLRQDEDGVTVDLADGEQLRARYVVGCDGGRSTVRKLLGVAFPGEPSRVETLLGEMASQEELTSVMTEVRKTQQRFGAMPGVFRVVVPAEGVAEDRTASPTLDEFKQQLRAHAGTDFGVHSPRWLSRFGDATRQAERYRVDRVFLAGDAAHIHPPTGGQGLNLGIQDAFNLGWKLAAEVDGWAPEGLLDTYHAERHPVATEVLDNTRAQIQLMSTEPGPQAVRRLMAELVEFENVNRYLIEKITAISVRYDVGEGHELLGRRMRDLALKHGRLYERMHEGRGLLLDQTGRLSVAGWEDRVDHVVEVSEELDVPAVLLRPDGHVVWAGEDQQELLTRMPAWFGAAT 6bru B 1.80 BS01 E5M B 1 I43 V69 K71 P111 M131 D132 R133 F134 L184 V196 I21 V36 K38 P75 M91 D92 R93 F94 L144 V156 2.7.11.1 Q99986 FAVGEIITDMAAAAWKVGLPICIYLADMNSSDAPCVVKVEPGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6enb A 1.84 BS01 III B 1 Q136 Y267 G268 G269 M270 E271 H295 Q296 H299 F314 E318 Y378 Y383 R563 K565 Q133 Y264 G265 G266 M267 E268 H292 Q293 H296 F311 E315 Y375 Y380 R560 K562 3.3.2.6 P09960 29051536 VDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHQISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD 6enc A 1.95 BS02 BGW A 1 Q136 Y267 G269 M270 H295 E296 W311 F314 E318 V367 L369 P374 D375 A377 Y378 P382 Y383 Q134 Y265 G267 M268 H293 E294 W309 F312 E316 V365 L367 P372 D373 A375 Y376 P380 Y381 3.3.2.6 P09960 29051536 IVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD 6end A 2.24 BS02 BGK A 1 Q136 A137 Y267 W311 F314 V367 L369 P374 D375 A377 Y378 P382 Q133 A134 Y264 W308 F311 V364 L366 P371 D372 A374 Y375 P379 3.3.2.6 P09960 29051536 VDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD 6eo8 H 1.94 BS01 III L 1 E23 I24 G25 M26 P28 W29 S115 D116 H119 P120 C122 G133 Y134 K135 R137 N159 Y184A K186D M201 K202 N205 R206 W207 E8 I9 G10 M11 P13 W14 S112 D113 H116 P117 C119 G133 Y134 K135 R137 N155 Y181 K187 M202 K203 N208 R209 W210 3.4.21.5 P00734 25268757 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 6eo8 H 1.94 BS03 2FN H 1 Y60A E97A I174 D189 A190 E192 V213 W215 G216 E217 G219 C220 R221A K224 G226 F227 Y228 Y47 E94 I170 D190 A191 E193 V216 W218 G219 E220 G221 C222 R224 K227 G229 F230 Y231 3.4.21.5 P00734 25268757 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 6eo9 H 1.84 BS03 2OJ H 1 Y60A E97A I174 D189 A190 C191 E192 V213 W215 G216 E217 G219 G226 F227 Y228 Y47 E94 I172 D192 A193 C194 E195 V218 W220 G221 E222 G223 G231 F232 Y233 3.4.21.5 P00734 25268757 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 6ep4 A 2.30 BS01 DME A 1 W82 Y128 E197 P285 Y332 H438 W80 Y126 E195 P283 Y330 H432 3.1.1.8 P06276 29186056 DIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNPQETQNQSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6ep4 A 2.30 BS02 FUL A 1 L249 F278 V280 P281 L247 F276 V278 P279 3.1.1.8 P06276 29186056 DIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNPQETQNQSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6eqp A 2.35 BS01 BUW A 1 W82 G116 G117 Q119 T120 S198 W231 P285 L286 S287 F329 Y332 W79 G113 G114 Q116 T117 S195 W228 P282 L283 S284 F326 Y329 3.1.1.8 P06276 29186056 IIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNPQETQNQSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6eqq A 2.40 BS01 H19 A 1 D70 S72 G116 G117 T120 W231 L286 S287 V288 Y332 F398 D67 S69 G113 G114 T117 W228 L283 S284 V285 Y329 F395 3.1.1.8 P06276 29186056 IIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNPQETQNQSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6eqq A 2.40 BS03 UNL A 1 P285 F329 Y332 P282 F326 Y329 3.1.1.8 P06276 29186056 IIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNPQETQNQSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6equ A 1.65 BS02 BVE A 1 N62 H64 N67 Q92 H94 H96 H119 F131 L198 T199 T200 W209 N63 H65 N68 Q93 H95 H97 H120 F131 L198 T199 T200 W209 4.2.1.1 P00918 29199489 GMSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 6esj A 2.98 BS01 PRM A 1 W82 G116 G117 T120 Y128 E197 S198 W231 P285 L286 S287 Y332 F398 H438 W80 G114 G115 T118 Y126 E195 S196 W229 P283 L284 S285 Y330 F396 H436 3.1.1.8 P06276 29186056 DIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6esj B 2.98 BS01 GLY B 1 L29 D129 L26 D126 3.1.1.8 P06276 29186056 IIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6esj B 2.98 BS02 PRM B 1 D70 W82 G116 G117 E197 S198 W231 P285 L286 S287 F329 Y332 F398 H438 I442 D67 W79 G113 G114 E194 S195 W228 P282 L283 S284 F326 Y329 F395 H435 I439 3.1.1.8 P06276 29186056 IIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6esy A 2.80 BS01 TFX A 1 G116 G117 T120 S198 W231 L286 G114 G115 T118 S196 W229 L284 3.1.1.8 P06276 29186056 DIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6esy A 2.80 BS02 TFX A 2 W82 P285 F329 Y332 H438 W80 P283 F327 Y330 H436 3.1.1.8 P06276 29186056 DIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6esy B 2.80 BS03 TFX B 2 W82 P285 F329 Y332 W79 P282 F326 Y329 3.1.1.8 P06276 29186056 IIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6euv A 2.70 BS01 21G A 1 F323 F325 R355 H357 E361 K376 F404 Q406 M431 N510 V511 L512 F72 F74 R104 H106 E110 K125 F153 Q155 M180 N255 V256 L257 P31345 29202182 NDDIDQSLIIAARNIVRRASVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMGVSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETHGTERLTITYS 6euv A 2.70 BS02 21G A 2 L281 H285 R293 R299 L30 H34 R42 R48 P31345 29202182 NDDIDQSLIIAARNIVRRASVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMGVSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETHGTERLTITYS 6euv C 2.70 BS02 21G C 2 L281 E282 H285 R293 V295 L33 E34 H37 R45 V47 P31345 29202182 EVRNDDIDQSLIIAARNIVRRASVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMGVSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETHGTERLTITYSSS 6euw A 1.00 BS01 BYB A 1 I319 S320 F323 S324 R332 H357 E361 F363 K376 F404 Q406 N425 M427 H428 I1 S2 F5 S6 R14 H39 E43 F45 K58 F86 Q88 N103 M105 H106 Q2LG68 29202182 ISSSFSFGGFTFKRTSGSSVKKEEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEMSLRGVRVSK 6eux A 2.05 BS01 BYB A 1 Q325 R326 F327 W359 E363 K378 F406 Y434 E511 V512 Q40 R41 F42 W74 E78 K93 F121 Y149 E217 V218 Q5V8X3 29202182 SQSMIVACRKIIRRSIVPLELAVEIANVACDIIRAALGRQRFGRLELKRISGRGFKNDEEILIGNGTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDLIILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFDQWGYEESPKASELHGINESMNASDYTLKGVVVTRNVIDDFITKNLSLIKRTGEVIMGANDV 6euy A 3.00 BS01 BYB A 1 F323 F325 R332 R355 H357 E361 F363 K376 F404 Q406 M431 N510 V511 L512 F72 F74 R81 R104 H106 E110 F112 K125 F153 Q155 M180 N254 V255 L256 P31345 29202182 NDDIDQSLIIAARNIVRRASVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETHGTERLTITYSS 6evj A 3.90 BS02 NUC V 1 R279 H326 K328 W363 G364 G366 G368 Q369 A370 P371 K373 Y388 K389 S390 P392 P393 R503 H505 V512 N514 K534 R561 T562 N563 G564 K569 N691 R274 H321 K323 W358 G359 G361 G363 Q364 A365 P366 K368 Y383 K384 S385 P387 P388 R498 H500 V507 N509 K529 R556 T557 N558 G559 K564 N686 H6QM92 29202182 SMENFVRTNFNPMILERAEKTMKEYGENPQNEGNKFAAISTHMEVCFMYSDFHFIDLEGNTIVKENDDAMLKHRFEIIEGQERNIAWTIVNSICNMTENSKPRFLPDLYDYKTNKFIEIGVTRRKVEDYYYEKASKLKGENVYIHIFSFDGEEMATDDEYILDEESRARIKTRLFVLRQELATAGLWDSFRQSEKLEEEFSYPPTFQRLANQSLPPSFKDYHQFKAYVSSFKANGNIEAKLGAMSEKVNAQIESFDPRTIRELELPEGKFCTQRSKFLLMDAMKLSVLNPAHEGEGIPMKDAKACLDTFWGWKKATIIKKHEKGVNTNYLMIWEQLLESIKEMEGKFLNLKKTNHLKWGLGEGQAPEKMDFEDCKEVPDLFQYKSEPPEKRKLASWIQSEFNKASELTNSNWIEFDELGNDVAPIEHIASRRRNFFTAEVSQCRASEYIMKAVYINTALLNSSCTAMEEYQVIPIITKCRDTSGQRRTNLYGFIIKGRSHLRNDTDVVNFISLEFSLTDPRNEIHKWEKYCVLEIGDMEIRTSISTIMKPVYLYVRTNGTSKIKMKWGMEMRRCLLQSLQQVESMIEAESAVKEKDMTEPFFRNRENDWPIGESPQGIEKGTIGKVCRVLLAKSVFNSIYASAQLEGFSAESRKLLLLIQAFRDNLDPGTFDLKGLYEAIEECIINDPWVLLNASWFNSFLKAVQLSMG 6evj B 3.90 BS01 NUC R 1 R135 R353 K669 N671 R672 S673 I674 L675 N676 T677 R135 R348 K664 N666 R667 S668 I669 L670 N671 T672 2.7.7.48 H6QM91 29202182 MDVNPMLIFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVIRTHDYSSRGIWKTNSETGAQQLNPIDGPLPEDNEPSGYAQTDCVLELIEGLDRSHPGLFETACQETIDAIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRKNGYKLNESGRLIDFLKDVLLSFENDSMEVTTHFQKKKRIRDMITQRTIGKKRVKLTKKNYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVELLARNICERLEQSGLPVGGNEKKAKLANVIKKMMAKSTDEELSYTITGDNTKWNENQNPRIFLAMVLRITAGQPEWFRDLLAVAPIMFSNKVARLGRGYMFESKSMHLRTQISAENLSDINLRYFNEDTKKKIEKIRHLMVEGTASLSPGMMMGMFNMLSTVLGVSVLNLGQREILKRTYWWDGLQSSDDFALIINGHFKEDIQQGVNHFYRTCKLVGINMSQKKSYINKTGTFEFTSFFYRYGFVANFSMELPSFGVAGNNESADMSIGTTVIKTNMINNDLGPATAQMAIQLFIKDYRYTYRCHRGDTNLETRRTKSIKRLWTETISKAGLLVADGGPNPYNLRNLHIPEVCLKWSLMDPDYRGRLCNPNNPFVHHMEVESTNLAVVMPAHGPAKSLEYDAVATTHSWTPKRNRSILNTNQRGILEDERIYQKCCQVFEKFFPSSTYRRPIGMASMLDAMLSRARIDARIDLESGRISSQDFSEITNTCKAIEALKRQG 6evj B 3.90 BS02 NUC V 1 H32 G33 T34 G37 Y38 T201 K237 Y355 M356 E358 R365 N676 H32 G33 T34 G37 Y38 T196 K232 Y350 M351 E353 R360 N671 2.7.7.48 H6QM91 29202182 MDVNPMLIFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVIRTHDYSSRGIWKTNSETGAQQLNPIDGPLPEDNEPSGYAQTDCVLELIEGLDRSHPGLFETACQETIDAIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRKNGYKLNESGRLIDFLKDVLLSFENDSMEVTTHFQKKKRIRDMITQRTIGKKRVKLTKKNYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVELLARNICERLEQSGLPVGGNEKKAKLANVIKKMMAKSTDEELSYTITGDNTKWNENQNPRIFLAMVLRITAGQPEWFRDLLAVAPIMFSNKVARLGRGYMFESKSMHLRTQISAENLSDINLRYFNEDTKKKIEKIRHLMVEGTASLSPGMMMGMFNMLSTVLGVSVLNLGQREILKRTYWWDGLQSSDDFALIINGHFKEDIQQGVNHFYRTCKLVGINMSQKKSYINKTGTFEFTSFFYRYGFVANFSMELPSFGVAGNNESADMSIGTTVIKTNMINNDLGPATAQMAIQLFIKDYRYTYRCHRGDTNLETRRTKSIKRLWTETISKAGLLVADGGPNPYNLRNLHIPEVCLKWSLMDPDYRGRLCNPNNPFVHHMEVESTNLAVVMPAHGPAKSLEYDAVATTHSWTPKRNRSILNTNQRGILEDERIYQKCCQVFEKFFPSSTYRRPIGMASMLDAMLSRARIDARIDLESGRISSQDFSEITNTCKAIEALKRQG 6evj C 3.90 BS01 NUC R 1 G37 R38 E40 R46 W49 G38 R39 E41 R47 W50 H6QM90 29202182 GMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMKWMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTWWNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDINPGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKISPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGGEAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEILRSNPTDEQAVNICKAALGIRINNSFSFGGYNFKRVKGSSQRTEKAVLTGNLQTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLMITLMVFSQEEKMLKAVRGDLNFVNRANQRLNPMYQLLRHFQKDSSTLLKNWGTEEIDPIMGIAGIMPDGTINKTQTLMGVRLSQGGVDEYSFNERIRVNIDKYLRVRNEKGELLISPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTNTYHWIIKNWELLKTQWMTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRTLFQQMRDVEGTFDSIQIIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLLIRGNSQVFNYNQMENVIIVLGKSVGSPSILTESSSIESAVLRGFLILGKANSKYGPVLTIGELDKLGRGEKANVLIGQGDTVLVMKRKRDSSILTDSQT 6evj C 3.90 BS02 NUC M 1 Q257 I260 R264 D304 E305 Q306 F323 S337 F357 E361 K376 F404 N422 L428 N429 Y432 S519 A521 Q258 I261 R265 D305 E306 Q307 F324 S338 F358 E362 K377 F405 N423 L429 N430 Y433 S520 A522 H6QM90 29202182 GMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMKWMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTWWNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDINPGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKISPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGGEAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEILRSNPTDEQAVNICKAALGIRINNSFSFGGYNFKRVKGSSQRTEKAVLTGNLQTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLMITLMVFSQEEKMLKAVRGDLNFVNRANQRLNPMYQLLRHFQKDSSTLLKNWGTEEIDPIMGIAGIMPDGTINKTQTLMGVRLSQGGVDEYSFNERIRVNIDKYLRVRNEKGELLISPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTNTYHWIIKNWELLKTQWMTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRTLFQQMRDVEGTFDSIQIIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLLIRGNSQVFNYNQMENVIIVLGKSVGSPSILTESSSIESAVLRGFLILGKANSKYGPVLTIGELDKLGRGEKANVLIGQGDTVLVMKRKRDSSILTDSQT 6evj E 3.90 BS01 NUC S 1 R135 N671 R672 S673 I674 N676 T677 R135 N663 R664 S665 I666 N668 T669 2.7.7.48 H6QM91 29202182 MDVNPMLIFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVIRTHDYSSRGIWKTNSETGAQQLNPIDGPLPEDNEPSGYAQTDCVLELIEGLDRSHPGLFETACQETIDAIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRKNGYKLNESGRLIDFLKDVLLSFENDSMEVTTHFQKKKRMITQRTIGKKRVKLTKKNYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVELLARNICERLEQSGLPVGGNEKKAKLANVIKKMMAKSTDEELSYTITGDNTKWNENQNPRIFLAMVLRITAGQPEWFRDLLAVAPIMFSNKVARLGRGYMFESKSMHLRTQISAENLSDINLRYFNEDTKKKIEKIRHLMVEGTASLSPGMMMGMFNMLSTVLGVSVLNLGQREILKRTYWWDGLQSSDDFALIINGHFKEDIQQGVNHFYRTCKLVGINMSQKKSYINKTGTFEFTSFFYRYGFVANFSMELPSFGVAGNNESADMSIGTTVIKTNMINNDLGPATAQMAIQLFIKDYRYTYRCHRGDTNLETRRTKSIKRLWTETISKAGLLVADGGPNPYNLRNLHIPEVCLKWSLMDPDYRGRLCNPNNPFVHHMEVESTNLAVVMPAHGPAKSLEYDAVATTHSWTPKRNRSILNTNQRGILEDERIYQKCCQVFEKFFPSSTYRRPIGMASMLDAMLSRARIDARIDLESGRISSQDFSEITNTCKAIEALKRQG 6evj F 3.90 BS01 NUC N 1 I260 D304 Q306 F323 S337 F357 E361 F363 K376 F404 N422 N429 Y432 S519 A521 I262 D306 Q308 F325 S339 F359 E363 F365 K378 F406 N424 N431 Y434 S521 A523 H6QM90 29202182 SGMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMKWMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTWWNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDINPGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKISPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGGEAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEILRSNPTDEQAVNICKAALGIRINNSFSFGGYNFKRVKGSSQRTEKAVLTGNLQTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLMITLMVFSQEEKMLKAVRGDLNFVNRANQRLNPMYQLLRHFQKDSSTLLKNWGTEEIDPIMGIAGIMPDGTINKTQTLMGVRLSQGGVDEYSFNERIRVNIDKYLRVRNEKGELLISPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTNTYHWIIKNWELLKTQWMTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRTLFQQMRDVEGTFDSIQIIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLLIRGNSQVFNYNQMENVIIVLGKSVGSPERSILTESSSIESAVLRGFLILGKANSKYGPVLTIGELDKLGRGEKANVLIGQGDTVLVMKRKRDSSIL 6evj F 3.90 BS02 NUC S 1 G37 R38 E40 R46 W49 M53 G39 R40 E42 R48 W51 M55 H6QM90 29202182 SGMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMKWMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTWWNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDINPGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKISPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGGEAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEILRSNPTDEQAVNICKAALGIRINNSFSFGGYNFKRVKGSSQRTEKAVLTGNLQTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLMITLMVFSQEEKMLKAVRGDLNFVNRANQRLNPMYQLLRHFQKDSSTLLKNWGTEEIDPIMGIAGIMPDGTINKTQTLMGVRLSQGGVDEYSFNERIRVNIDKYLRVRNEKGELLISPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTNTYHWIIKNWELLKTQWMTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRTLFQQMRDVEGTFDSIQIIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLLIRGNSQVFNYNQMENVIIVLGKSVGSPERSILTESSSIESAVLRGFLILGKANSKYGPVLTIGELDKLGRGEKANVLIGQGDTVLVMKRKRDSSIL 6evk C 2.90 BS02 MGP C 1 F323 R339 T355 F357 E361 F363 K376 F404 Q406 N429 M431 F324 R340 T356 F358 E362 F364 K377 F405 Q407 N427 M429 H6QM90 29202182 SGMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMKWMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTWWNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDINPGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKISPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGGEAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEILRSNPTDEQAVNICKAALGIRINSFSFGGYNFKRVKGSSQRTEKAVLTGNLQTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLMITLMVFSQEEKMLKAVRGDLNFVNQRLNPMYQLLRHFQKDSSTLLKNWGTEEIDPIMGIAGIMPDGTINKTQTLMGVRLSQRVNIDKYLRVRNEKGELLISPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTNTYHWIIKNWELLKTQWMTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRTLFQQMRDVEGTFDSIQIIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLLIRGNSQVFNYNQMENVIIVLGKSVGSPERSILTESSSIESAVLRGFLILGKANSKYGPVLTIGELDKLGRGEKANVLIGQGDTVLVMKRKRDS 6ex7 A 1.95 BS01 UNL A 1 H122 D124 H189 C208 K211 G219 N220 H250 H92 D94 H159 C178 K181 G189 N190 H220 3.5.2.6 C7C422 IRPTIGQQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR 6eyu A 2.50 BS01 RET A 1 W77 T81 L114 G118 Y130 F174 Y177 P178 W181 C212 K213 W77 T81 L114 G118 Y130 F174 Y177 P178 W181 C212 K213 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS02 MUN A 1 F67 L68 Y71 M75 F67 L68 Y71 M75 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS03 MUN A 2 S27 F218 L219 Y222 L223 K226 S27 F218 L219 Y222 L223 K226 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS04 MUN A 3 L86 Y101 L86 Y101 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS05 MUN A 4 D102 G105 G109 F112 T113 D102 G105 G109 F112 T113 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS06 MUN A 5 I47 F50 L83 I47 F50 L83 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS07 MUN A 6 T128 Y131 L135 T128 Y131 L135 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS08 MUN A 7 I195 L196 Q200 V207 I195 L196 Q200 V207 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS09 MUN A 8 I21 I22 M25 L63 N64 I21 I22 M25 L63 N64 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS10 MUN A 9 R100 L143 R100 L143 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS11 MUN C 1 F67 M75 F67 M75 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu A 2.50 BS12 MUN C 2 L32 Q42 I46 L32 Q42 I46 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu B 2.50 BS02 MUN A 10 K43 I46 I47 F50 W54 K43 I46 I47 F50 W54 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu B 2.50 BS03 RET B 1 W77 T81 I84 L114 G118 Y130 G133 L137 F174 Y177 P178 W181 C212 K213 W77 T81 I84 L114 G118 Y130 G133 L137 F174 Y177 P178 W181 C212 K213 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu B 2.50 BS05 MUN B 2 R100 A110 G139 Y142 L143 P147 E150 R100 A110 G139 Y142 L143 P147 E150 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu B 2.50 BS08 MUN B 5 Q14 P15 A19 I22 Q14 P15 A19 I22 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu B 2.50 BS09 MUN B 6 I21 L63 N64 I21 L63 N64 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAELEHH 6eyu C 2.50 BS01 MUN A 11 D102 G109 F112 D102 G109 F112 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAEL 6eyu C 2.50 BS02 MUN B 7 I46 F50 W54 V79 L83 I46 F50 W54 V79 L83 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAEL 6eyu C 2.50 BS03 RET C 1 W77 T81 I84 L114 T117 G118 G133 L137 F174 Y177 P178 P209 C212 K213 W77 T81 I84 L114 T117 G118 G133 L137 F174 Y177 P178 P209 C212 K213 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAEL 6eyu C 2.50 BS05 MUN C 4 Y101 G105 F112 Y101 G105 F112 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAEL 6eyu C 2.50 BS07 MUN C 5 R100 G139 L143 R100 G139 L143 G0QG75 28948217 MVYEAITAGGFGSQPFILAYIITAMISGLLFLYLPRKLDVPQKFGIIHFFIVVWSGLMYTNFLNQSFLSDYAWYMDWMVSTPLILLALGLTAFHGADTKRYDLLGALLGAEFTLVITGLLAQAQGSITPYYVGVLLLLGVVYLLAKPFREIAEESSDGLARAYKILAGYIGIFFLSYPTVWYISGIDALPGSLNILDPTQTSIALVVLPFFCKQVYGFLDMYLIHKAEL 6ezq A 2.39 BS01 C7K A 1 Y150 L198 K199 S202 F211 W214 R222 L238 H242 R257 I290 A291 Y144 L192 K193 S196 F205 W208 R216 L232 H236 R251 I284 A285 P02768 29193545 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPCTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 6ezq A 2.39 BS02 C7K A 2 S342 V344 L345 R348 P384 L387 I388 N391 Y411 V426 L430 A449 L453 L457 R485 F488 S489 S336 V338 L339 R342 P378 L381 I382 N385 Y405 V420 L424 A443 L447 L451 R479 F482 S483 P02768 29193545 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPCTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 6f07 B 3.60 BS01 ZN B 1 P13 C14 C17 C24 P11 C12 C15 C22 P40969 NRTTQLKSKHPCSVCTRRKVKCDRMIPCGNCRKRGQDSECMKSTKLITASSSKEYLPDLLLFWQNYEYWITNIGLYKTKQRDLTRTPANLDTDTEECMFWMNYLQKDQSFQLMNFAMENLGALYFGSIGDISELYLRVEQYWDRRADKNHSVDGKYWDALIWSVFTMCIYYMPVEKLAEIFSVYPLHEYLGSNKRLNWEDGMQLVMCQNFARCSLFQLKQCDFMAHPDIRLVQAYLILATTTFPYDEPLLANSLLTQCIHTFKNFHVDDFRPLLNDDPVESIAKVTLGRIFYRLCGCDYLQSGPRKPIALHTEVSSLLVYREENSTEVLYWKIISLDRDLDQYLNKSSKPPLKTLDAIRRELDIFQYKVDSLEEDFRSNNSRFQKFIALFQISTVSWKLFKMYLIYYDTADSLLKVIHYSKVIISLIVNNFHAKSEFFNRHPMVMQTITRVVSFISFYQIFVESAAVKQLLVDLTELTANLPTIFGSKLDKLVYLTERLSKLKLLWDKVQLLDSGDSFYHPVFKILQNDIKIIELKNDEMFSLIKGLGSLVPLNSDFRTIVEEFQSEYNISDILS 6f07 B 3.60 BS02 ZN B 2 C14 C30 C33 C42 C12 C28 C31 C40 P40969 NRTTQLKSKHPCSVCTRRKVKCDRMIPCGNCRKRGQDSECMKSTKLITASSSKEYLPDLLLFWQNYEYWITNIGLYKTKQRDLTRTPANLDTDTEECMFWMNYLQKDQSFQLMNFAMENLGALYFGSIGDISELYLRVEQYWDRRADKNHSVDGKYWDALIWSVFTMCIYYMPVEKLAEIFSVYPLHEYLGSNKRLNWEDGMQLVMCQNFARCSLFQLKQCDFMAHPDIRLVQAYLILATTTFPYDEPLLANSLLTQCIHTFKNFHVDDFRPLLNDDPVESIAKVTLGRIFYRLCGCDYLQSGPRKPIALHTEVSSLLVYREENSTEVLYWKIISLDRDLDQYLNKSSKPPLKTLDAIRRELDIFQYKVDSLEEDFRSNNSRFQKFIALFQISTVSWKLFKMYLIYYDTADSLLKVIHYSKVIISLIVNNFHAKSEFFNRHPMVMQTITRVVSFISFYQIFVESAAVKQLLVDLTELTANLPTIFGSKLDKLVYLTERLSKLKLLWDKVQLLDSGDSFYHPVFKILQNDIKIIELKNDEMFSLIKGLGSLVPLNSDFRTIVEEFQSEYNISDILS 6f58 A 2.25 BS01 NUC C 1 K66 N150 S162 L163 T196 P212 F213 K215 A216 K27 N105 S117 L118 T151 P167 F168 K170 A171 O15178 GELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSH 6f58 A 2.25 BS02 NUC D 1 R69 R70 K147 Y198 T204 K207 N211 F213 F217 R30 R31 K102 Y153 T159 K162 N166 F168 F172 O15178 GELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSH 6f58 B 2.25 BS01 NUC C 1 R69 R70 K147 Y198 T204 K207 I208 N211 F213 F217 R30 R31 K102 Y153 T159 K162 I163 N166 F168 F172 O15178 GELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDA 6f58 B 2.25 BS02 NUC D 1 K66 K103 N150 S162 L163 T196 P212 K215 A216 K27 K64 N105 S117 L118 T151 P167 K170 A171 O15178 GELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDA 6f59 B 2.15 BS02 NUC D 1 K66 R101 K103 N150 S162 L163 T196 P212 A216 K27 R62 K64 N111 S123 L124 T157 P173 A177 O15178 GELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGDPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERS