5gv5 A 2.89 BS01 MSW A 1 G39 T40 W104 S105 Q106 D134 Q157 I189 H224 L278 A281 I285 G39 T40 W104 S105 Q106 D134 Q157 I189 H224 L278 A281 I285 3.1.1.3 P41365 LPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSTQLGYTPCWISPPPFMLNDTQVNTEYMVNAITALYAGSGNNKLPVLTWSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAVSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPAAAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIVTP 5gv5 B 2.89 BS01 MSW B 1 T40 W104 S105 Q106 Q157 I189 H224 L278 A281 I285 T40 W104 S105 Q106 Q157 I189 H224 L278 A281 I285 3.1.1.3 P41365 LPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSTQLGYTPCWISPPPFMLNDTQVNTEYMVNAITALYAGSGNNKLPVLTWSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAVSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPAAAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIVTP 5gv5 C 2.89 BS01 MSW C 1 T40 W104 S105 Q106 D134 Q157 I189 H224 L278 I285 T40 W104 S105 Q106 D134 Q156 I188 H223 L277 I284 3.1.1.3 P41365 LPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSTQLGYTPCWISPPPFMLNDTQVNTEYMVNAITALYAGSGNNKLPVLTWSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDAAVSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPAAAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIVTP 5gv5 F 2.89 BS01 MSW F 1 G39 T40 W104 S105 Q106 Q157 I189 H224 L278 I285 G39 T40 W104 S105 Q106 Q157 I189 H224 L278 I285 3.1.1.3 P41365 LPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSTQLGYTPCWISPPPFMLNDTQVNTEYMVNAITALYAGSGNNKLPVLTWSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAVSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPAAAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIVTP 5gv5 H 2.89 BS01 MSW H 1 T40 G41 S105 Q106 Q157 I189 H224 L278 A281 A282 I285 T40 G41 S105 Q106 Q157 I189 H224 L278 A281 A282 I285 3.1.1.3 P41365 LPSGSDPAFSQPKSVLDAGLTCQGASPSSVSKPILLVPGTGTTGPQSFDSNWIPLSTQLGYTPCWISPPPFMLNDTQVNTEYMVNAITALYAGSGNNKLPVLTWSQGGLVAQWGLTFFPSIRSKVDRLMAFAPDYKGTVLAGPLDALAVSAPSVWQQTTGSALTTALRNAGGLTQIVPTTNLYSATDEIVQPQVSNSPLDSSYLFNGKNVQAQAVCGPLFVIDHAGSLTSQFSYVVGRSALRSTTGQARSADYGITDCNPLPANDLTPEQKVAAAALLAPAAAAIVAGPKQNCEPDLMPYARPFAVGKRTCSGIVTP 5gvi A 1.87 BS01 ZN A 1 C230 C233 C280 C283 C125 C128 C171 C174 A0A0R4ILB8 SHMGMVPGLLNLGNTAFMNSLLQGLAACPSFIRWLEDFTSERETQLSRSLMQLLKALSSHVPGEDDVLDAGGLLEALRLYRWHISSFEEQDAHELFHVLTSSLEEEQERRTRHPFHGRLTSYMACKRCEQQSPVHYDSFDSLSLSIPSRPVTLDQCLQHFISSETIKEVECENCTKQQAGELVGEVLESQRTTFVKQLKLGKLPQCLCIHLQRLTWSKEGSPIKRQEHVQFTEYLSLDRYKAIANGVDSEHCSEYLFRLTAVLVHHGDMHSGHFITYRRCPAAPRGTSPFSSQWLWVSDDSVRKASLQEVLSSSAYLLFYERMQRP 5gwo A 2.82 BS01 MG A 1 D220 K239 D306 D310 D159 K178 D245 D249 3.1.3.16 Q6L5H6 28827170 PVWGCASTRGRSAEMEDASAAVPRFADVPVRLLASRRDLDALGLDADALRLPAHLFGVFDGHGGAEVANYCRERIHVVLSAALARLGKNLGEMGEVDMKEHWDDVFTKCFQRVDDEVSGRVTRVVNEVRSEPVTAENVGSTAVVALVCSSHVVVANCGDSRIVLCRGKEPVALSIDHKPDRKDERARIEAQGGKVIQWNGYRVFGMLAMSRSIGDRYLKPFVIPKPEVMVVPRAKDDDCLILASDGLWDVVSNEEACKVARRQILLWHKNNSTDPAAQAAADYLMRLALKKGSEDNITVIVVDLKP 5gwo A 2.82 BS02 MG A 2 D118 G119 D60 G61 3.1.3.16 Q6L5H6 28827170 PVWGCASTRGRSAEMEDASAAVPRFADVPVRLLASRRDLDALGLDADALRLPAHLFGVFDGHGGAEVANYCRERIHVVLSAALARLGKNLGEMGEVDMKEHWDDVFTKCFQRVDDEVSGRVTRVVNEVRSEPVTAENVGSTAVVALVCSSHVVVANCGDSRIVLCRGKEPVALSIDHKPDRKDERARIEAQGGKVIQWNGYRVFGMLAMSRSIGDRYLKPFVIPKPEVMVVPRAKDDDCLILASDGLWDVVSNEEACKVARRQILLWHKNNSTDPAAQAAADYLMRLALKKGSEDNITVIVVDLKP 5gwo A 2.82 BS03 MG A 3 D118 D306 D368 D60 D245 D295 3.1.3.16 Q6L5H6 28827170 PVWGCASTRGRSAEMEDASAAVPRFADVPVRLLASRRDLDALGLDADALRLPAHLFGVFDGHGGAEVANYCRERIHVVLSAALARLGKNLGEMGEVDMKEHWDDVFTKCFQRVDDEVSGRVTRVVNEVRSEPVTAENVGSTAVVALVCSSHVVVANCGDSRIVLCRGKEPVALSIDHKPDRKDERARIEAQGGKVIQWNGYRVFGMLAMSRSIGDRYLKPFVIPKPEVMVVPRAKDDDCLILASDGLWDVVSNEEACKVARRQILLWHKNNSTDPAAQAAADYLMRLALKKGSEDNITVIVVDLKP 5gwo C 2.82 BS01 A8S C 1 K76 L102 S107 F125 H130 L132 F174 L178 L179 N182 K46 L72 S77 F95 H100 L102 F144 L148 L149 N152 K4N2F7 28827170 TEYVRRFHRHEPRDHQCSSAVAKHIKAPVHLVWSLVRRFDQPQLFKPFVSRCEMKGNIEIGSVREVNVKSGLPATRSTERLELLDDNEHILSVRFVGGDHRLKNYSSILTVHPEVIDGRPGTLVIESFVVDVPEGNTKDETCYFVEALLKCNLKSLAEVSERLVV 5gwp A 2.58 BS02 MG A 2 D306 D310 D245 D249 3.1.3.16 Q6L5H6 28827170 PVWGCASTRGRSAEMEDASAAVPRFADVPVRLLASRRDLDALGLDADALRLPAHLFGVFDGHGGAEVANYCRERIHVVLSAALARLGKNLGEMGEVDMKEHWDDVFTKCFQRVDDEVSGRVTRVVGEVRSEPVTAENVGSTAVVALVCSSHVVVANCGDSRIVLCRGKEPVALSIDHKPDRKDERARIEAQGGKVIQWNGYRVSGILAMSRSIGDRYLKPFVIPKPEVMVVPRAKDDDCLILASDGLWDVVSNEEACKVARRQILLWHKNNSTDPAAQAAADYLMRLALKKGSEDNITVIVVDLK 5gwp C 2.58 BS01 A8S C 1 K76 F78 V98 A104 S107 F125 H130 L132 F174 L178 N182 K42 F44 V64 A70 S73 F91 H96 L98 F140 L144 N148 K4N2F7 28827170 RRFHRHEPRDHQCSSAVAKHIKAPVHLVWSLVRRFDQPQLFKPFVSRCEMKGNIEIGSVREVNVKSGLPATRSTERLELLDDNEHILSVRFVGGDHRLKNYSSILTVHPEVIDGRPGTLVIESFVVDVPEGNTKDETCYFVEALLKCNLKSLAEVSERLVV 5gwp D 2.58 BS01 A8S D 1 K76 F78 V98 S107 F125 H130 L132 L178 L179 N182 K30 F32 V52 S61 F79 H84 L86 L132 L133 N136 K4N2F7 28827170 CSSAVAKHIKAPVHLVWSLVRRFDQPQLFKPFVSRCEMKGNIEIGSVREVNVKSGLPATRSTERLELLDDNEHILSVRFVGGDHRLKNYSSILTVHPEVIDGRPGTLVIESFVVDVPEGNTKDETCYFVEALLKCNLKSLAEVSERLVV 5h4r A 1.70 BS01 CTT A 1 N55 D58 W76 H141 H142 N187 Q188 W198 H272 Y274 L281 E326 W360 N362 E370 F372 N34 D37 W55 H120 H121 N166 Q167 W177 H251 Y253 L260 E305 W339 N341 E349 F351 R9RX81 28838949 RAKIPEIKIASRKIPNNAALKFVKDMKIGWNLGNTFDAAFENPSFDDELLYETAWCGVKTTKQMIDTVKKAGFNTIRIPVSWHNHVTGSNFTISKRWLDRVQQVVDYAMKNKMYVIINIHHDIMPGYYYPNSQHLQTSIKYVKSIWTQVATRFKNYNDHLIFEAVNQPRLTGSRFEWWLDMNNPECRDAVEAINKLNQVFVDTVRSTGGNNVSRYLMVPGYAAAPEYVLIDEFKIPKDSSKYKNRIIISVHAYRPYNFALQAPNESGSVSEWSVNSEESRRDIDYFMDKLYDKFVSKGIPVVIGEFGARDKNGNLQSRVEFAAYYVRAARARGITCCWWDNNAFYGNGENFGLLDRKTLKWVYPEIVSAMMKYAR 5i4e A 2.25 BS01 AOV A 1 N146 P147 Y148 K149 Y154 S200 G201 A202 G203 K204 T205 E206 N256 S259 S260 A480 G481 N98 P99 Y100 K101 Y106 S152 G153 A154 G155 K156 T157 E158 N208 S211 S212 A432 G433 P05095 EWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERASEQTKSDYLKRANELVQWINDKQASLESRDFGDSIESVQSFMNAHKEYKKTEKPPKGQEVSELEAIYNSLQTKLREPFVAPAGLTPNEIDSTWSALEKAEQEHAEALRIELKRQKKIAVLLQKYNRILKKLENWATTKSVYLGSNETGDSITAVQAKLKNLEAFDGECQSLEGQSNSDLLSILAQLTELNYNGVPELTERKDTFFAQQWTGVKSSAETYKNT 5i4e A 2.25 BS02 MG A 1 T205 S260 T157 S212 P05095 EWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERASEQTKSDYLKRANELVQWINDKQASLESRDFGDSIESVQSFMNAHKEYKKTEKPPKGQEVSELEAIYNSLQTKLREPFVAPAGLTPNEIDSTWSALEKAEQEHAEALRIELKRQKKIAVLLQKYNRILKKLENWATTKSVYLGSNETGDSITAVQAKLKNLEAFDGECQSLEGQSNSDLLSILAQLTELNYNGVPELTERKDTFFAQQWTGVKSSAETYKNT 5l7p B 1.90 BS01 BUU B 1 G34 E36 I65 A67 L69 A70 L73 G105 A109 Y151 M154 Q155 A158 Q173 G34 E36 I65 A67 L69 A70 L73 G105 A109 Y151 M154 Q155 A158 Q173 6.1.1.1 Q57834 28650092 MDEFEMIKRNTSEIISEEELREVLKKDEKSAAIGFEPSGKIHLGHYLQIKKMIDLQNAGFDIIIILADLAAYLNQKGELDEIRKIGDYNKKVFEAMGLKAKYVYGSEFALDKDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVIYPIMQVNAAHYMGVDVNVGGMEQRKIHMLQRELLPKKVVCIHNPVLTGLDGEGKMSSSKGNFIAVDDSPEEIRAKIKKAYCPAGVVEGNPIMEIAKYFLEYPLTIKRPEKFGGDLTVNSYEELESLFKNKELHPMRLKNAVAEELIKILEPIRKRL 5lry S 1.40 BS02 F3S S 1 T226 N228 C230 W235 P242 C249 L250 C252 T222 N224 C226 W231 P238 C245 L246 C248 1.12.99.6 P69740 PRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAEEVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTCASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVDRMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACSSTRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRV 5lry L 1.40 BS01 FCO L 1 C79 V82 H83 A507 P508 R509 L512 V530 P531 T532 C579 C78 V81 H82 A506 P507 R508 L511 V529 P530 T531 C578 1.12.99.6 P0ACD8 STQYETQGYTINNAGRRLVVDPITRIDGHMRCEVNINDQNVITNAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDNANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSPGYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVKIHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMIPDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNVLPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLGRILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAPRGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEILRTLHSFDPCLACSTH 5lrz A 2.00 BS01 73Y A 1 F22 N51 S52 A55 D93 M98 L103 I104 L107 G108 G135 F138 Y139 W162 F170 T184 F6 N35 S36 A39 D77 M82 L87 I88 L91 G92 G119 F122 Y123 W146 F154 T168 P07900 METFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 5ls7 B 1.16 BS01 ACO B 1 W23 E25 Y26 S65 L66 R67 V68 R73 R74 R75 G76 G78 Q79 G101 V102 E103 V107 M108 A110 F111 A114 W23 E25 Y26 S65 L66 R67 V68 R73 R74 R75 G76 G78 Q79 G101 V102 E103 V107 M108 A110 F111 A114 P37613 28832133 MKLTIIRLEKFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARFNERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPGVSCWWMADAGVEDRGVMTAFMQALGFTAQQGGWEKCS 5ls7 D 1.16 BS01 III A 1 F32 A36 G37 Y58 I60 R67 I68 I69 S70 V71 N72 G73 A76 H77 A79 S80 V81 G82 D83 I84 V85 I86 I87 A88 S89 F90 V91 T92 M93 P94 D95 A98 W101 P103 N104 A106 Y107 F108 G110 D111 N112 F7 A11 G12 Y33 I35 R42 I43 I44 S45 V46 N47 G48 A51 H52 A54 S55 V56 G57 D58 I59 V60 I61 I62 A63 S64 F65 V66 T67 M68 P69 D70 A73 W76 P78 N79 A81 Y82 F83 G85 D86 N87 4.1.1.11 P0A790 28832133 CAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA 5ls7 D 1.16 BS02 74C D 1 D31 F32 M114 D6 F7 M89 4.1.1.11 P0A790 28832133 CAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA 5lsp A 2.61 BS01 III X 1 Y566 F569 T582 C584 Y48 F51 T64 C66 2.7.10.1 P08581 28827556 GCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYRE 5lsp P 2.61 BS01 III Y 1 Y566 K567 F569 T582 C584 T618 N620 T621 Y48 K49 F51 T64 C66 T100 N102 T103 2.7.10.1 P08581 28827556 GCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYRE 5ltf A 2.43 BS01 MG A 1 D88 E101 C102 D89 E102 C103 2.7.7.48 A0A059U381 HDEIISELRELCLNYIEQDERLSRQKLNFLGQREPRMVLIEGLKLLSRCIEIDSADKSGCTHNHDDKSVETILVESGIVCPGLPLIIPDGYKLIDNSLILLECFVRSTPASFEKKFIEDTNKLACIREDLAVAGVTLVPIVDGRCDYDNSFMPEWANFKFRDLLFKLLEYSNQDEKVFEESEYFRLCE 5ltf A 2.43 BS02 MG A 2 E50 D88 E51 D89 2.7.7.48 A0A059U381 HDEIISELRELCLNYIEQDERLSRQKLNFLGQREPRMVLIEGLKLLSRCIEIDSADKSGCTHNHDDKSVETILVESGIVCPGLPLIIPDGYKLIDNSLILLECFVRSTPASFEKKFIEDTNKLACIREDLAVAGVTLVPIVDGRCDYDNSFMPEWANFKFRDLLFKLLEYSNQDEKVFEESEYFRLCE 5ltn A 1.88 BS01 MG A 1 D88 E101 D89 E102 2.7.7.48 A0A059U381 HDEIISELRELCLNYIEQDERLSRQKLNFLGQREPRMVLIEGLKLLSRCIEIDSADKSGCTHNHDDKSVETILVESGIVCPGLPLIIPDGYKLIDNSLILLECFVRSTPASFEKKFIEDTNKLACIREDLAVAGVTLVPIVDGRCDYDNSFMPEWANFKFRDLLFKLLEYSNQDEKVFEESEY 5ltn A 1.88 BS03 XI7 A 1 S46 E50 D88 E101 S47 E51 D89 E102 2.7.7.48 A0A059U381 HDEIISELRELCLNYIEQDERLSRQKLNFLGQREPRMVLIEGLKLLSRCIEIDSADKSGCTHNHDDKSVETILVESGIVCPGLPLIIPDGYKLIDNSLILLECFVRSTPASFEKKFIEDTNKLACIREDLAVAGVTLVPIVDGRCDYDNSFMPEWANFKFRDLLFKLLEYSNQDEKVFEESEY 5ltn B 1.88 BS02 MG B 2 D88 C102 D89 C103 2.7.7.48 A0A059U381 HDEIISELRELCLNYIEQDERLSRQKLNFLGQREPRMVLIEGLKLLSRCIEIDSADKSGCTHNHDDKSVETILVESGIVCPGLPLIIPDGYKLIDNSLILLECFVRSTPASFEKKFIEDTNKLACIREDLAVAGVTLVPIVDGRCDYDNSFMPEWANFKFRDLLFKLLEYSNQDEKVFEESEYFRLCESLKTTI 5lyg A 1.60 BS01 MLI A 1 R442 R448 R499 R116 R122 R173 O00481 28862425 SAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA 5lyk A 1.70 BS01 FLC A 1 W421 R442 R448 R499 W95 R116 R122 R173 O00481 28862425 SAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA 5m3l A 3.80 BS01 HEM A 1 L52 F53 H69 L97 H101 R104 F112 I115 L48 F49 H65 L93 H97 R100 F108 I111 P13579 DCCSYEDRREIRHIWDDVWSSSFTDRRVAIVRAVFDDLFKHYPTSKALFERVKIDEPESGEFKSHLVRVANGLKLLINLLDDTLVLQSHLGHLADQHIQRKGVTKEYFRGIGEAFARVLPQVLSCFNVDAWNRCFHRLVARIAKDLP 5m3l B 3.80 BS01 HEM B 1 F48 H64 R67 L72 L92 H96 R99 Y105 F106 F109 E138 F48 H64 R67 L72 L92 H96 R99 Y105 F106 F109 E138 P02218 KKQCGVLEGLKVKSEWGRAYGSGHDREAFSQAIWRATFAQVPESRSLFKRVHGDDTSHPAFIAHADRVLGGLDIAISTLDQPATLKEELDHLQVQHEGRKIPDNYFDAFKTAILHVVAAQLGRCYDREAWDACIDHIEDGIKGHH 5m3l C 3.80 BS01 HEM C 1 L43 R56 V57 H70 R73 I74 L98 Q101 H102 R105 H112 F113 F116 L41 R54 V55 H68 R71 I72 L96 Q99 H100 R103 H110 F111 F114 P11069 HEHCCSEEDHRIVQKQWDILWRDTESSKIKIGFGRLLLTKLAKDIPEVNDLFKRVDIEHAEGPKFSAHALRILNGLDLAINLLDDPPALDAALDHLAHQHEVREGVQKAHFKKFGEILATGLPQVLDDYDALAWKSCLKGILTKISSRL 5m3l D 3.80 BS01 HEM D 1 F53 H69 L97 H101 R104 F111 F114 F46 H62 L90 H94 R97 F104 F107 O61233 ECLVTESLKVKLQWASAFGHAHERVAFGLELWRDIIDDHPEIKAPFSRVRGDNIYSPEFGAHSQRVLSGLDITISMLDTPDMLAAQLAHLKVQHVERNLKPEFFDIFLKHLLHVLGDRLGTHFDFGAWHDCVDQIIDGIK 5m3l E 3.80 BS01 HEM E 1 L52 F53 R55 H69 L97 H101 R104 F112 I115 L48 F49 R51 H65 L93 H97 R100 F108 I111 P13579 DCCSYEDRREIRHIWDDVWSSSFTDRRVAIVRAVFDDLFKHYPTSKALFERVKIDEPESGEFKSHLVRVANGLKLLINLLDDTLVLQSHLGHLADQHIQRKGVTKEYFRGIGEAFARVLPQVLSCFNVDAWNRCFHRLVARIAKDLP 5m3l F 3.80 BS01 HEM F 1 F48 H64 R67 L72 L92 Q95 H96 R99 F106 F109 F48 H64 R67 L72 L92 Q95 H96 R99 F106 F109 P02218 KKQCGVLEGLKVKSEWGRAYGSGHDREAFSQAIWRATFAQVPESRSLFKRVHGDDTSHPAFIAHADRVLGGLDIAISTLDQPATLKEELDHLQVQHEGRKIPDNYFDAFKTAILHVVAAQLGRCYDREAWDACIDHIEDGIKGHH 5m3l G 3.80 BS01 HEM G 1 L43 F54 V57 H70 R73 I74 L98 H102 R105 H112 F113 F116 L41 F52 V55 H68 R71 I72 L96 H100 R103 H110 F111 F114 P11069 HEHCCSEEDHRIVQKQWDILWRDTESSKIKIGFGRLLLTKLAKDIPEVNDLFKRVDIEHAEGPKFSAHALRILNGLDLAINLLDDPPALDAALDHLAHQHEVREGVQKAHFKKFGEILATGLPQVLDDYDALAWKSCLKGILTKISSRL 5m3l H 3.80 BS01 HEM H 1 F53 R55 H69 R72 Q100 H101 R104 F111 F114 F46 R48 H62 R65 Q93 H94 R97 F104 F107 O61233 ECLVTESLKVKLQWASAFGHAHERVAFGLELWRDIIDDHPEIKAPFSRVRGDNIYSPEFGAHSQRVLSGLDITISMLDTPDMLAAQLAHLKVQHVERNLKPEFFDIFLKHLLHVLGDRLGTHFDFGAWHDCVDQIIDGIK 5m3l K 3.80 BS01 HEM K 1 L43 V57 H70 R73 I74 L98 H102 R105 H112 F113 F116 L41 V55 H68 R71 I72 L96 H100 R103 H110 F111 F114 P11069 HEHCCSEEDHRIVQKQWDILWRDTESSKIKIGFGRLLLTKLAKDIPEVNDLFKRVDIEHAEGPKFSAHALRILNGLDLAINLLDDPPALDAALDHLAHQHEVREGVQKAHFKKFGEILATGLPQVLDDYDALAWKSCLKGILTKISSRL 5m3l L 3.80 BS01 HEM L 1 F53 R55 H69 L77 L97 H101 F114 F46 R48 H62 L70 L90 H94 F107 O61233 ECLVTESLKVKLQWASAFGHAHERVAFGLELWRDIIDDHPEIKAPFSRVRGDNIYSPEFGAHSQRVLSGLDITISMLDTPDMLAAQLAHLKVQHVERNLKPEFFDIFLKHLLHVLGDRLGTHFDFGAWHDCVDQIIDGIK 5mfe A 1.95 BS01 III E 1 R33 S36 Q37 G41 N43 E72 W75 N79 S82 G83 G84 N85 I88 W117 S120 N121 S124 G125 E156 W159 N163 W201 R22 S25 Q26 G30 N32 E61 W64 N68 S71 G72 G73 N74 I77 W106 S109 N110 S113 G114 E145 W148 N152 W190 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfe A 1.95 BS03 CA A 2 E282 E285 E271 E274 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfe B 1.95 BS01 CA B 1 Q284 E285 E288 Q273 E274 E277 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQSH 5mfe C 1.95 BS06 CA C 6 Q18 N21 Q8 N11 28864298 SELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQSH 5mfe C 1.95 BS07 CA C 7 E288 Q291 E278 Q281 28864298 SELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQSH 5mff A 1.90 BS01 III E 1 Q71 E72 W75 Q113 E114 W117 E156 W159 E198 W201 Q239 E240 W243 Q60 E61 W64 Q102 E103 W106 E145 W148 E187 W190 Q228 E229 W232 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQ 5mff B 1.90 BS01 III E 1 Q71 E72 W75 E114 W117 E156 W159 E198 W201 E240 W243 E282 Q60 E61 W64 E103 W106 E145 W148 E187 W190 E229 W232 E271 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQ 5mff D 1.90 BS01 III F 1 E72 W75 E114 W117 E156 W159 E198 W201 E240 W243 E61 W64 E103 W106 E145 W148 E187 W190 E229 W232 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKL 5mfg A 1.90 BS01 III E 1 Q29 R33 S36 Q71 E72 L74 W75 S78 N79 E114 L116 W117 S120 N121 L158 W159 S162 N163 W201 W243 K260 E261 A262 G263 L265 E266 Q18 R22 S25 Q60 E61 L63 W64 S67 N68 E103 L105 W106 S109 N110 L147 W148 S151 N152 W190 W232 K249 E250 A251 G252 L254 E255 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQSH 5mfg C 1.90 BS01 III E 1 W75 S78 N79 W117 S120 N121 W159 Q194 Q197 W53 S56 N57 W95 S98 N99 W137 Q172 Q175 28864298 QMVQQLQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfg D 1.90 BS01 III E 1 W159 Q197 W201 S204 N205 W243 S246 N247 W148 Q186 W190 S193 N194 W232 S235 N236 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGG 5mfg D 1.90 BS08 CA D 1 N163 S166 N152 S155 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGG 5mfh A 2.00 BS01 III E 1 N43 I46 W75 N79 S82 G83 N85 I88 W117 S120 N121 S124 G125 G126 N127 I130 E156 W159 N163 S166 G167 N34 I37 W66 N70 S73 G74 N76 I79 W108 S111 N112 S115 G116 G117 N118 I121 E147 W150 N154 S157 G158 28864298 GSELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfh C 2.00 BS01 III F 1 R33 S36 N43 I46 E72 W75 N79 S82 G83 N85 I88 W117 S120 N121 S124 G125 N127 E156 W159 N163 S166 W201 R22 S25 N32 I35 E61 W64 N68 S71 G72 N74 I77 W106 S109 N110 S113 G114 N116 E145 W148 N152 S155 W190 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfi A 1.45 BS01 III C 1 G83 N84 N85 I88 N121 S124 G125 N126 N127 I130 E156 W159 N163 S166 G167 N168 N169 I172 W201 N205 S208 N240 G72 N73 N74 I77 N110 S113 G114 N115 N116 I119 E145 W148 N152 S155 G156 N157 N158 I161 W190 N194 S197 N229 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLEEAGAEPALEKLQSSPNEEVQKNAQAALEALNS 5mfi A 1.45 BS02 III D 1 E72 W75 E110 W117 E156 E61 W64 E99 W106 E145 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLEEAGAEPALEKLQSSPNEEVQKNAQAALEALNS 5mfi B 1.45 BS01 III D 1 G125 N127 I130 S166 G167 N168 N169 I172 E198 W201 A204 N205 S208 E236 N240 G115 N117 I120 S156 G157 N158 N159 I162 E188 W191 A194 N195 S198 E226 N230 28864298 SELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLEEAGAEPALEKLQSSPNEEVQKNAQAALEALNS 5mfk A 2.30 BS01 III C 1 S82 G83 W117 N121 S124 G125 N127 I130 K155 E156 W159 N163 S166 G167 I172 W201 N205 S72 G73 W107 N111 S114 G115 N117 I120 K145 E146 W149 N153 S156 G157 I162 W191 N195 28864298 SELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQKLIEAGALSPLVKLLDDASEEVIKEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIKEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIKEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIKEAVWAIANIASGNNEMKQKLEEAGALPALEKLQSHANEEVQKNAQAALEAFN 5mfm A 2.30 BS06 MG A 1 E193 N234 Q236 E183 N224 Q226 28864298 SELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLGGGKRKRKRKRKR 5mfm B 2.30 BS05 MG B 2 Q71 N108 Q110 Q60 N97 Q99 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLGGKRKRKRKRKR 5mfm C 2.30 BS05 MG C 1 E151 Q155 Q194 I195 E141 Q145 Q184 I185 28864298 SELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLGGKRKRKRKRKR 5mfm F 2.30 BS01 MG F 1 E193 N234 E182 N223 28864298 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLGGGKRKRKRKRKR 5mfo A 1.30 BS01 CA A 1 Q18 N21 Q9 N12 28864298 GSELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGAEPALEQLQSSPNEKIQKEAQEALEKIQS 5mfo B 1.30 BS01 CA B 1 P65 N66 E67 P55 N56 E57 28864298 SELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGAEPALEQLQSSPNEKIQKEAQEALEKIQS 5mfo D 1.30 BS01 CA D 1 S124 G125 S117 G118 28864298 GPGSELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGAEPALEQLQSSPNEKIQKEAQEALEKIQ 5mfo D 1.30 BS02 CA D 2 P149 E151 P142 E144 28864298 GPGSELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGAEPALEQLQSSPNEKIQKEAQEALEKIQ 5mfo D 1.30 BS04 CA D 4 E12 Q15 E5 Q8 28864298 GPGSELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGAEPALEQLQSSPNEKIQKEAQEALEKIQ 5n2n A 2.05 BS02 BEF A 1 D1050 C1051 Q1052 V1081 S1082 G1083 K1105 D79 C80 Q81 V110 S111 G112 K134 2.7.13.3 O22267 28860196 SSGLVPSDDEFLRGKRVLVVDDNFISRKVATGKLKKMGVSEVEQCDSGKEALRLVTEGLTQREEQGSVDKLPFDYIFMDCQMPEMDGYEATREIRKVEKSYGVRTPIIAVSGHDPGSEEARETIQAGMDAFLDKSLNQLANVIREIESK 5n6i A 3.60 BS01 NUC G 1 R161 S165 A168 N172 N196 Y200 Y201 K372 R443 R13 S17 A20 N24 N48 Y52 Y53 K224 R295 2.7.7.86 Q8C6L5 KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD 5n6i A 3.60 BS03 NUC I 1 K240 K315 G316 R342 K92 K167 G168 R194 2.7.7.86 Q8C6L5 KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD 5n6i A 3.60 BS04 NUC J 1 P243 T334 K335 T338 P95 T186 K187 T190 2.7.7.86 Q8C6L5 KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD 5n6i B 3.60 BS02 NUC H 1 P243 R244 K323 T334 K335 T338 P95 R96 K175 T186 K187 T190 2.7.7.86 Q8C6L5 KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD 5n6i B 3.60 BS03 NUC I 1 R161 S165 N172 N196 Y200 Y201 K372 R13 S17 N24 N48 Y52 Y53 K224 2.7.7.86 Q8C6L5 KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD 5n6i C 3.60 BS02 NUC H 1 K240 K315 R342 K92 K167 R194 2.7.7.86 Q8C6L5 KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD 5n6i E 3.60 BS03 NUC M 1 R244 T334 K335 T338 R96 T186 K187 T190 2.7.7.86 Q8C6L5 KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD 5n6i F 3.60 BS01 NUC K 1 P243 K323 T334 K335 T338 P95 K175 T186 K187 T190 2.7.7.86 Q8C6L5 KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD 5ne1 B 2.09 BS01 OK3 B 1 C69 S70 K73 H105 S130 N132 N170 T235 G236 S237 N238 G240 C49 S50 K53 H85 S110 N112 N150 T215 G216 S217 N218 G219 3.5.2.6 Q9RBQ1 NAPTDAAITAASDFAALEKACAGRLGVTLLDTASGRRIGHRQDERFPMCSTFKSMLAATVLSQAERMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGPPAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQQLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVAGGAPWVLTAYLQAGAISYEQRASVLAQVGRIADRLIG 5ne2 A 1.19 BS01 DGL A 1 S70 H105 S130 N132 N170 G236 S237 S50 H85 S110 N112 N150 G216 S217 3.5.2.6 Q9RBQ1 NAPTDAAITAASDFAALEKACAGRLGVTLLDTASGRRIGHRQDERFPMCSTFKSMLAATVLSQAERMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGPPAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQQLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVAGGAPWVLTAYLQAGAISYEQRASVLAQVGRIADRLIG 5ne3 A 1.35 BS01 NXL A 1 C68 S69 K72 H104 S129 N131 N169 T215 K233 T234 G235 S236 C48 S49 K52 H84 S109 N111 N149 T195 K213 T214 G215 S216 3.5.2.6 B2FRP5 APTDAAITAASDFAALEKACAGRLGVTLLDTASGRRIGHRQDERFPMCSTFKSMLAATVLSQAERMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGPPAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQQLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVAGGAPWVLTAYLQAGAISYEQRASVLAQVGRIADRLIG 5nes A 1.61 BS01 III E 1 S23 G24 N70 D99 S23 G24 N70 D99 A0A069Q9V4 ATQGVFTLPANTRFGVTAFANSSGTQTVNVLVNNETAATFSGQSTNNAVIGTQVLNSGSSGKVQVQVSVNGRPSDLVSAQVILTNELNFALVGSEDGTDNDYNDAVVVINWPLG 5ney B 1.55 BS01 III E 1 V69 N70 R72 D96 G97 T98 V69 N70 R72 D96 G97 T98 A0A069Q9V4 ATQGVFTLPANTRFGVTAFANSSGTQTVNVLVNNETAATFSGQSTNNAVIGTQVLNSGSSGKVQVQVSVNGRPSDLVSAQVILTNELNFALVGSEDGTDNDYNDAVVVINWPLG 5nf0 A 1.27 BS01 III H 1 L113 G114 L113 G114 A0A069Q9V4 ATQGVFTLPANTRFGVTAFANSSGTQTVNVLVNNETAATFSGQSTNNAVIGTQVLNSGSSGKVQVQVSVNGRPSDLVSAQVILTNELNFALVGSEDGTDNDYNDAVVVINWPLG 5nf0 B 1.27 BS01 III E 1 S23 G24 T98 D99 S23 G24 T98 D99 A0A069Q9V4 ATQGVFTLPANTRFGVTAFANSSGTQTVNVLVNNETAATFSGQSTNNAVIGTQVLNSGSSGKVQVQVSVNGRPSDLVSAQVILTNELNFALVGSEDGTDNDYNDAVVVINWPLG 5nf0 B 1.27 BS06 OXE E 1 V69 N70 V69 N70 A0A069Q9V4 ATQGVFTLPANTRFGVTAFANSSGTQTVNVLVNNETAATFSGQSTNNAVIGTQVLNSGSSGKVQVQVSVNGRPSDLVSAQVILTNELNFALVGSEDGTDNDYNDAVVVINWPLG 5nf0 C 1.27 BS05 OXE H 1 R72 D96 G97 T98 R72 D96 G97 T98 A0A069Q9V4 ATQGVFTLPANTRFGVTAFANSSGTQTVNVLVNNETAATFSGQSTNNAVIGTQVLNSGSSGKVQVQVSVNGRPSDLVSAQVILTNELNFALVGSEDGTDNDYNDAVVVINWPLG 5ngb A 2.90 BS01 8WH A 1 K708 M752 W760 I777 Y813 I825 E826 V827 V828 M900 I910 D911 K512 M556 W564 I581 Y617 I629 E630 V631 V632 M697 I707 D708 Q3UDT3 28857471 VKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNLWSLEQPFSIELIEGRKVNAMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVDCPIAWANLMLFDYKDQLKTGERCLYMWPSVLLNPAGTVRGNPNTESAAALVIYLPEVAPVYFPALEKILELLREILERELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLTAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESW 5nm8 A 1.93 BS01 PLP A 1 V24 K26 N47 L70 M152 M194 S195 R210 G212 T213 V22 K24 N45 L68 M150 M192 S193 R208 G210 T211 Q31LH9 QIAERLASLRSQLPPSVQLIAVSKNHPAAAIREAYAAGQRHFGENRVQEAIAKQAELTDLPDLTWHLLGKLQSNKARKAVEHFDWIHSVDSWALAERLDRIAGELGRSPKLCLQVKLLPDPNKAGWDPADLRAELPQLSQLQQVQIRGLMVIAPLGLTAAETQALFAQARTFAAELQQQAPQLRLTELSMGMSSDWPLAVAEGATWIRVGTQLFGPR 5nm8 B 1.93 BS01 PLP B 1 V24 K26 N47 L70 I154 M194 S195 R210 V211 G212 T213 V22 K24 N45 L68 I149 M189 S190 R205 V206 G207 T208 Q31LH9 QIAERLASLRSQLPPSVQLIAVSKNHPAAAIREAYAAGQRHFGENRVQEAIAKQAELTDLPDLTWHLLGKLQSNKARKAVEHFDWIHSVDSWALAERLDRIAGELGRSPKLCLQVKLLPDAGWDPADLRAELPQLSQLQQVQIRGLMVIAPLGLTAAETQALFAQARTFAAELQQQAPQLRLTELSMGMSSDWPLAVAEGATWIRVGTQLFG 5o3m A 2.23 BS01 9JE A 1 C150 L320 H327 C147 L317 H324 B9A9M6 28857436 PIQDLRDAIALLQQHDNQYLETDHPVDPNAELAGVYRHIGAGGTVKRPTRIGPAMMFNNIKGYPHSRILVGMHASRQRAALLLGCEASQLALEVGKAVKKPVAPVVVPASSAPCQEQIFLADDPDFDLRTLLPAPTNTPIDAGPFFCLGLALASDPVDASLTDVTIHRLCVQGRDELSMFLAAGRHIEVFRQKAEAAGKPLPITINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQRPVELVQGVSVPEKAIARAEIVIEGELLPGVRVREDQHTNSGHAMPEFPGYCGGANPSLPVIKVKAVTMRNNAILQTLVGPGEEHTTLAGLPTEASIWNAVEAAIPGFLQNVYAHTAGGGKFLGILQVKKRQPADEGRQGQAALLALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTIPGIRGHQLDPSQTPEYSPSIRGNGISCKTIFDCTVPWALKSHFERAPFADVDPRPFAPEYFARLEK 5o3m A 2.23 BS02 9JE A 2 D402 E403 D404 K470 D399 E400 D401 K467 B9A9M6 28857436 PIQDLRDAIALLQQHDNQYLETDHPVDPNAELAGVYRHIGAGGTVKRPTRIGPAMMFNNIKGYPHSRILVGMHASRQRAALLLGCEASQLALEVGKAVKKPVAPVVVPASSAPCQEQIFLADDPDFDLRTLLPAPTNTPIDAGPFFCLGLALASDPVDASLTDVTIHRLCVQGRDELSMFLAAGRHIEVFRQKAEAAGKPLPITINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQRPVELVQGVSVPEKAIARAEIVIEGELLPGVRVREDQHTNSGHAMPEFPGYCGGANPSLPVIKVKAVTMRNNAILQTLVGPGEEHTTLAGLPTEASIWNAVEAAIPGFLQNVYAHTAGGGKFLGILQVKKRQPADEGRQGQAALLALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTIPGIRGHQLDPSQTPEYSPSIRGNGISCKTIFDCTVPWALKSHFERAPFADVDPRPFAPEYFARLEK 5o3m B 2.23 BS01 9JE B 1 D402 E403 D404 V465 K470 D399 E400 D401 V462 K467 B9A9M6 28857436 PIQDLRDAIALLQQHDNQYLETDHPVDPNAELAGVYRHIGAGGTVKRPTRIGPAMMFNNIKGYPHSRILVGMHASRQRAALLLGCEASQLALEVGKAVKKPVAPVVVPASSAPCQEQIFLADDPDFDLRTLLPAPTNTPIDAGPFFCLGLALASDPVDASLTDVTIHRLCVQGRDELSMFLAAGRHIEVFRQKAEAAGKPLPITINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQRPVELVQGVSVPEKAIARAEIVIEGELLPGVRVREDQHTNSGHAMPEFPGYCGGANPSLPVIKVKAVTMRNNAILQTLVGPGEEHTTLAGLPTEASIWNAVEAAIPGFLQNVYAHTAGGGKFLGILQVKKRQPADEGRQGQAALLALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTIPGIRGHQLDPSQTPEYSPSIRGNGISCKTIFDCTVPWALKSHFERAPFADVDPRPFAPEYFAR 5o3m C 2.23 BS02 9JE C 2 C150 I169 C147 I166 B9A9M6 28857436 PIQDLRDAIALLQQHDNQYLETDHPVDPNAELAGVYRHIGAGGTVKRPTRIGPAMMFNNIKGYPHSRILVGMHASRQRAALLLGCEASQLALEVGKAVKKPVAPVVVPASSAPCQEQIFLADDPDFDLRTLLPAPTNTPIDAGPFFCLGLALASDPVDASLTDVTIHRLCVQGRDELSMFLAAGRHIEVFRQKAEAAGKPLPITINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQRPVELVQGVSVPEKAIARAEIVIEGELLPGVRVREDQHTNSGHAMPEFPGYCGGANPSLPVIKVKAVTMRNNAILQTLVGPGEEHTTLAGLPTEASIWNAVEAAIPGFLQNVYAHTAGGGKFLGILQVKKRQPADEGRQGQAALLALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTIPGIRGHQLDPSQTPEYSPSIRGNGISCKTIFDCTVPWALKSHFERAPFADVDPRPFAPEYFA 5o3m C 2.23 BS03 9JE C 3 P107 V109 F229 P104 V106 F226 B9A9M6 28857436 PIQDLRDAIALLQQHDNQYLETDHPVDPNAELAGVYRHIGAGGTVKRPTRIGPAMMFNNIKGYPHSRILVGMHASRQRAALLLGCEASQLALEVGKAVKKPVAPVVVPASSAPCQEQIFLADDPDFDLRTLLPAPTNTPIDAGPFFCLGLALASDPVDASLTDVTIHRLCVQGRDELSMFLAAGRHIEVFRQKAEAAGKPLPITINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQRPVELVQGVSVPEKAIARAEIVIEGELLPGVRVREDQHTNSGHAMPEFPGYCGGANPSLPVIKVKAVTMRNNAILQTLVGPGEEHTTLAGLPTEASIWNAVEAAIPGFLQNVYAHTAGGGKFLGILQVKKRQPADEGRQGQAALLALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTIPGIRGHQLDPSQTPEYSPSIRGNGISCKTIFDCTVPWALKSHFERAPFADVDPRPFAPEYFA 5o3m D 2.23 BS02 9JE D 2 Q369 V405 D406 Q366 V402 D403 B9A9M6 28857436 PIQDLRDAIALLQQHDNQYLETDHPVDPNAELAGVYRHIGAGGTVKRPTRIGPAMMFNNIKGYPHSRILVGMHASRQRAALLLGCEASQLALEVGKAVKKPVAPVVVPASSAPCQEQIFLADDPDFDLRTLLPAPTNTPIDAGPFFCLGLALASDPVDASLTDVTIHRLCVQGRDELSMFLAAGRHIEVFRQKAEAAGKPLPITINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQRPVELVQGVSVPEKAIARAEIVIEGELLPGVRVREDQHTNSGHAMPEFPGYCGGANPSLPVIKVKAVTMRNNAILQTLVGPGEEHTTLAGLPTEASIWNAVEAAIPGFLQNVYAHTAGGGKFLGILQVKKRQPADEGRQGQAALLALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTIPGIRGHQLDPSQTPEYSPSIRGNGISCKTIFDCTVPWALKSHFERAPFADVDPRPFAPEYFARL 5o3m E 2.23 BS01 9JE E 1 D402 E403 D404 V465 K470 E474 D399 E400 D401 V462 K467 E471 B9A9M6 28857436 PIQDLRDAIALLQQHDNQYLETDHPVDPNAELAGVYRHIGAGGTVKRPTRIGPAMMFNNIKGYPHSRILVGMHASRQRAALLLGCEASQLALEVGKAVKKPVAPVVVPASSAPCQEQIFLADDPDFDLRTLLPAPTNTPIDAGPFFCLGLALASDPVDASLTDVTIHRLCVQGRDELSMFLAAGRHIEVFRQKAEAAGKPLPITINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQRPVELVQGVSVPEKAIARAEIVIEGELLPGVRVREDQHTNSGHAMPEFPGYCGGANPSLPVIKVKAVTMRNNAILQTLVGPGEEHTTLAGLPTEASIWNAVEAAIPGFLQNVYAHTAGGGKFLGILQVKKRQPADEGRQGQAALLALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTIPGIRGHQLDPSQTPEYSPSIRGNGISCKTIFDCTVPWALKSHFERAPFADVDPRPFAPEYFARL 5o3m F 2.23 BS01 9JE F 1 D402 D404 K470 E474 D398 D400 K466 E470 B9A9M6 28857436 IQDLRDAIALLQQHDNQYLETDHPVDPNAELAGVYRHIGAGGTVKRPTRIGPAMMFNNIKGYPHSRILVGMHASRQRAALLLGCEASQLALEVGKAVKKPVAPVVVPASSAPCQEQIFLADDPDFDLRTLLPAPTNTPIDAGPFFCLGLALASDPVDASLTDVTIHRLCVQGRDELSMFLAAGRHIEVFRQKAEAAGKPLPITINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQRPVELVQGVSVPEKAIARAEIVIEGELLPGVRVREDQHTNSGHAMPEFPGYCGGANPSLPVIKVKAVTMRNNAILQTLVGPGEEHTTLAGLPTEASIWNAVEAAIPGFLQNVYAHTAGGGKFLGILQVKKRQPADEGRQGQAALLALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTIPGIRGHQLDPSQTPEYSPSIRGNGISCKTIFDCTVPWALKSHFERAPFADVDPRPFAPEYFA 5o3n A 2.05 BS01 MN A 1 D166 H189 E233 D163 H186 E230 B2DCZ6 28857436 PINDLRSAIALLQRHPGHYIETDHPVDPNAELAGVYRHIGAGGTVKRPTRTGPAMMFNSVKGYPGSRILVGMHASRERAALLLGCVPSKLAQHVGQAVKNPVAPVVVPASQAPCQEQVFYADDPDFDLRKLLPAPTNTPIDAGPFFCLGLVLASDPEDTSLTDVTIHRLCVQERDELSMFLAAGRHIEVFRKKAEAAGKPLPVTINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQQPVELVQGVAVKEKAIARAEIIIEGELLPGVRVREDQHTNTGHAMPEFPGYCGEANPSLPVIKVKAVTMRNHAILQTLVGPGEEHTTLAGLPTEASIRNAVEEAIPGFLQNVYAHTAGGGKFLGILQVKKRQPSDEGRQGQAALIALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTLPGIRGHQLDPSQSPDYSTSIRGNGISCKTIFDCTVPWALKARFERAPFMEVDPTPWAPELF 5o3n A 2.05 BS02 4LU A 1 C150 D166 T168 I169 H170 R171 F183 A185 R188 H189 C221 F222 E223 E233 L320 H327 C147 D163 T165 I166 H167 R168 F180 A182 R185 H186 C218 F219 E220 E230 L317 H324 B2DCZ6 28857436 PINDLRSAIALLQRHPGHYIETDHPVDPNAELAGVYRHIGAGGTVKRPTRTGPAMMFNSVKGYPGSRILVGMHASRERAALLLGCVPSKLAQHVGQAVKNPVAPVVVPASQAPCQEQVFYADDPDFDLRKLLPAPTNTPIDAGPFFCLGLVLASDPEDTSLTDVTIHRLCVQERDELSMFLAAGRHIEVFRKKAEAAGKPLPVTINMGLDPAIYIGACFEAPTTPFGYNELGVAGALRQQPVELVQGVAVKEKAIARAEIIIEGELLPGVRVREDQHTNTGHAMPEFPGYCGEANPSLPVIKVKAVTMRNHAILQTLVGPGEEHTTLAGLPTEASIRNAVEEAIPGFLQNVYAHTAGGGKFLGILQVKKRQPSDEGRQGQAALIALATYSELKNIILVDEDVDIFDSDDILWAMTTRMQGDVSITTLPGIRGHQLDPSQSPDYSTSIRGNGISCKTIFDCTVPWALKARFERAPFMEVDPTPWAPELF 5o86 A 1.69 BS01 FAD A 1 Y252 L264 S265 N266 L267 S268 L271 F298 E301 I302 W305 K306 S309 K372 G375 R378 M379 W381 A382 N403 D409 G410 N414 G415 G418 I419 W421 S422 Y241 L253 S254 N255 L256 S257 L260 F287 E290 I291 W294 K295 S298 K361 G364 R367 M368 W370 A371 N392 D398 G399 N403 G404 G407 I408 W410 S411 4.1.99.3 Q8PYK9 28858395 MNPKRIRALKSGKQGDGPVVYWMSRDQRAEDNWALLFSRAIAKEANVPVVVVFCLTDEFLEAGIRQYEFMLKGLQELEVSLSRKKIPSFFLRGDPGEKISRFVKDYNAGTLVTDFSPLRIKNQWIEKVISGISIPFFEVDAHNVVPCWEASQKHEYAAHTFRPKLYALLPEFLEEFPELEPNSVTPETLSDVLETGVKALLPERALLKNKDPLFEPWHFEPGEKAAKKVMESFIADRLDSYGALRNDPTKNMLSNLSPYLHFGQISSQRVVLEVEKAESNPGSKKAFLDEILIWKEISDNFCYYNPGYDGFESFPSWAKESLNAHRNDVRSHIYTLEEFEAGKTHDPLWNASQMELLSTGKMHGYTRMYWAKKILEFSESPEKALEIAICLNDRYELDGRDPNGYAGIAWSIGGVHDRAWGEREVTGKIRYMSYEGCKRKFDVKLYIEKYS 5of4 B 4.40 BS01 SF4 B 1 L115 C116 H118 C134 T138 C155 F157 C190 F193 L105 C106 H108 C124 T128 C145 F147 C180 F183 3.6.4.12 P18074 YFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHREDQL 5oik A 3.70 BS01 NUC N 1 K149 K331 S1131 H1417 K139 K287 S1075 H1351 2.7.7.6 SACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEHGGCGRYQPRIRRSGLELYAEWKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIP 5oik A 3.70 BS03 NUC T 1 P323 K331 K346 R351 R358 Q461 P462 T854 A855 Y859 R1416 E1433 D1437 P279 K287 K302 R307 R314 Q417 P418 T810 A811 Y815 R1350 E1367 D1371 2.7.7.6 SACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEHGGCGRYQPRIRRSGLELYAEWKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIP 5oik B 3.70 BS01 NUC N 1 M200 K210 R385 D386 K427 I489 P498 M173 K183 R358 D359 K400 I462 P471 2.7.7.6 A5PJW8 EITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELEGTNRRYTKRDCSTFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV 5oik B 3.70 BS02 NUC P 1 G465 Q468 Q731 R841 H842 R890 K942 G438 Q441 Q704 R814 H815 R863 K915 2.7.7.6 A5PJW8 EITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELEGTNRRYTKRDCSTFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV 5oik B 3.70 BS03 NUC T 1 S190 V469 L747 R897 G1077 R1078 R1085 M1089 S163 V442 L720 R870 G1050 R1051 R1058 M1062 2.7.7.6 A5PJW8 EITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELEGTNRRYTKRDCSTFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV 5oik E 3.70 BS01 NUC N 1 I84 T111 S113 I83 T110 S112 Q2T9T3 DDEEETYRLWKIRKTIMQLCHDRGYLVTQDGLDQTLEEFKAQFGGKPSEGRPRRTDLTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVARYFGIKRGQVVKIIRPSETAGRYITYRLVQ 5oik Z 3.70 BS01 NUC P 1 K579 R619 K369 R409 O00267 DPNLWTVKCKIGEERATAISLMRKFIAYQFTDTPLQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVKEVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKAPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFREHNFQPGDNVEVCEGELINLQGKILSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPQTVGVIVRLERETFQVLNMYGKVVTVRHQAVTRKKDNRFAVALDSEQNNIHVKDIVKVIDGPHSGREGEIRHLFRSFAFLHCKKLVENGGMFVCKTRHLVLANELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVG 5ool I 3.06 BS01 III l 1 G77 L78 E85 G38 L39 E46 Q7Z7H8 SKAVTRHRRVMHFQRQKLMAVTEYIPPKPAIHPSCLPGLIRLLRREIAAVFQDNRMIAVCQNVALSAEDKLLMRHQLRKHKILMKVFPNQVLKPFLEDSKYQNLLPLFVGHNMLLVSEEPKVKEMVRILRTVPFLPLLGGCIDDTILSRQGFINYSKL 5ool J 3.06 BS01 III t 1 A109 L111 A92 L94 Q9Y3B7 GVIRAIVRAGLAMPGPPLGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARQTGKEVAGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVK 5ool N 3.06 BS01 III l 1 E168 E170 E171 E122 E124 E125 Q9NX20 KPKLRFIERAPLVPKVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGKYWGKFYMPKRV 5ool P 3.06 BS01 NUC B 1 T86 Q87 H88 H89 R108 K113 S118 R120 N121 V122 W151 E152 S155 S157 T48 Q49 H50 H51 R70 K75 S80 R82 N83 V84 W113 E114 S117 S119 Q9H0U6 VENEAVAPEFTNRNPRNLELLSVARKERGWRTVFPSREFWHRLRVIRTQHHVEALVEHQNGKVVVSASTREWAIKKHLYSTRNVVACESIGRVLAQRCLEAGINFMVYQPTPWEAASDSMKRLQSAMTEGGVVLREPQRIY 5ool 0 3.06 BS01 ZN 0 1 C110 C113 C123 C126 C32 C35 C45 C48 Q9BYC8 AAPKNRRTIEVNRCRRRNPQKLIKVKNNIDVCPECGHLKQKHVLCAYCYEKVCKETAEIRRQIGKQEGGPFKAPTIETVVLYTGETPSEQDQGKRIIERDRKRPSWFT 5ool 6 3.06 BS01 NUC B 1 R52 S53 R56 R59 R126 R26 S27 R30 R33 R81 Q96DV4 RRTPPLGPMPNSDIDLSNLERLEKYRSFDRYRRRAEQEAQAPHWWRTYREYFGRTQQLLERKQAIQELRANVEEERAARLRTASVPLDAVRAEWERTCGPYHKQRLAEYYGLYRDLFHGATFVPRVPLHVAYAVGEDDLMPVYCGNEVTPTEAAQAPEVTYEAELWTLLLTSLDGHLLEPDAEYLHWLLTNIPGNRVAEGQVTCPYLPPFPARGSGIHRLAFLLFKQDQPIDFSYQLAQRTFRTFDFYKKHQETMTPAGLSFFQCRWDDSVTYIFHQLLDMREPVFEFVRPPPYHPKQKRFPHRQPLRYLDRYRDSHEPTYGIY 5ool 8 3.06 BS01 NUC B 1 F88 K119 W121 S122 L123 K125 Q126 R129 R133 F6 K37 W39 S40 L41 K43 Q44 R47 R51 Q9NQ50 IPIEDFITPLKFLDKARERPQVELTFEETERRALLLKKWSLYKQQERKMERDTIRAMLEAQQEALEELQLESPKLHAEAIKRDPNLFPFEKEGPHYTPP 5ool f 3.06 BS01 NUC B 1 E104 Q108 H111 N115 S124 E47 Q51 H54 N58 S67 Q96GC5 YKTKPTHGIGKYKHLIKAEVRAINLGTDYEYGVLNIHLTAYDMTLAESYAQYVHNLCNSLSIKVEESYAMPTKTILTTHERVVQISGLSATFAEIFLEIIQSSLPEGVRLSVKEHT 5ool v 3.06 BS01 PNS v 1 R6 Q43 K44 E46 A50 R51 Q54 L55 R5 Q42 K43 E45 A49 R50 Q53 L54 L0R8F8 APWSREAVLSLYRALLRQGRQLRYTDRDFYFASIRREFRKNQKLEDAEARERQLEKGLVFLNGKLGRII 5ool w 3.06 BS01 PNS v 1 D111 S112 D38 S39 O14561 LTLEGIQDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKK 5oom N 3.03 BS01 III l 1 D114 E168 E170 E171 D68 E122 E124 E125 Q9NX20 KPKLRFIERAPLVPKVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGKYWGKFYMPKRV 5oom P 3.03 BS01 NUC B 1 T86 Q87 H88 H89 K113 R120 N121 V122 W151 E152 S157 T48 Q49 H50 H51 K75 R82 N83 V84 W113 E114 S119 Q9H0U6 VENEAVAPEFTNRNPRNLELLSVARKERGWRTVFPSREFWHRLRVIRTQHHVEALVEHQNGKVVVSASTREWAIKKHLYSTRNVVACESIGRVLAQRCLEAGINFMVYQPTPWEAASDSMKRLQSAMTEGGVVLREPQRIY 5oom f 3.03 BS01 NUC B 1 Q108 H111 N112 N115 S124 Q51 H54 N55 N58 S67 Q96GC5 YKTKPTHGIGKYKHLIKAEVRAINLGTDYEYGVLNIHLTAYDMTLAESYAQYVHNLCNSLSIKVEESYAMPTKTILTTHERVVQISGLSATFAEIFLEIIQSSLPEGVRLSVKEHT 5oom v 3.03 BS01 PNS v 1 P3 R6 N42 Q43 E46 A50 R51 Q54 L55 P2 R5 N41 Q42 E45 A49 R50 Q53 L54 L0R8F8 APWSREAVLSLYRALLRQGRQLRYTDRDFYFASIRREFRKNQKLEDAEARERQLEKGLVFLNGKLGRII 5or8 A 2.40 BS01 JR4 A 1 P1817 F1818 V1822 L1826 V1827 Y1830 F1872 N1873 V1879 P22 F23 V27 L31 V32 Y35 F77 N78 V84 Q9UIF9 28862840 HSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFY 5or9 A 2.00 BS01 JR5 A 1 W1887 P1888 F1889 L1891 P1892 V1893 F1943 N1944 I1950 W32 P33 F34 L36 P37 V38 F88 N89 I95 Q9UIF8 28862840 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFKV 5owq A 2.70 BS01 38O A 1 L42 A63 I110 E111 F112 C113 G116 L164 L13 A34 I74 E75 F76 C77 G80 L128 2.7.11.1 O94804 LDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIEEEELEDYIVEIEILATCDHPYIVKLLGAYKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADPYWMAPEVVMCEYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEE 5owq B 2.70 BS01 38O B 1 L42 A63 I110 E111 F112 C113 G116 L164 D175 V314 L11 A32 I72 E73 F74 C75 G78 L126 D137 V251 2.7.11.1 O94804 PNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIEEEELEDYIVEIEILATCDHPYIVKLLGAYKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADPYWMAPEVVMCETMDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEE 5owr A 2.30 BS01 1N1 A 1 A63 K65 I110 E111 F112 C113 P114 L164 D175 V314 A37 K39 I82 E83 F84 C85 P86 L136 D147 V279 2.7.11.1 O94804 YEHVRRDLDPNEVWEIVGELGGKVYKAKNKETGALAAAKVIETKEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEE 5suv A 1.75 BS01 COA B 1 D8 I30 E57 K61 G64 T65 G66 I67 F73 D9 I31 E58 K62 G65 T66 G67 I68 F74 2.7.8.7 A1KVH5 AMIYGIGTDIVSLKRIIRLNKKFGQAFAGRILTPEELLEFPQAGKPVNYLAKRFAAKEAFAKAVGTGIRGAVSFRNIGIGHDALGKPEFFYGPALSKWLEEQGISRVSLSMSDEEDTVLAFVVAEK 5suv A 1.75 BS02 COA C 1 K51 H80 L83 G84 K85 P86 M110 S111 K52 H81 L84 G85 K86 P87 M111 S112 2.7.8.7 A1KVH5 AMIYGIGTDIVSLKRIIRLNKKFGQAFAGRILTPEELLEFPQAGKPVNYLAKRFAAKEAFAKAVGTGIRGAVSFRNIGIGHDALGKPEFFYGPALSKWLEEQGISRVSLSMSDEEDTVLAFVVAEK 5suv B 1.75 BS01 COA B 1 K51 H80 L83 G84 K85 P86 M110 S111 D112 K52 H81 L84 G85 K86 P87 M111 S112 D113 2.7.8.7 A1KVH5 AMIYGIGTDIVSLKRIIRLNKKFGQAFAGRILTPEELLEFPQAGKPVNYLAKRFAAKEAFAKAVGTGIRGAVSFRNIGIGHDALGKPEFFYGPALSKWLEEQGISRVSLSMSDEEDTVLAFVVAEK 5suv B 1.75 BS02 COA B 2 D8 I30 F53 E57 K61 G64 T65 G66 I67 F73 D9 I31 F54 E58 K62 G65 T66 G67 I68 F74 2.7.8.7 A1KVH5 AMIYGIGTDIVSLKRIIRLNKKFGQAFAGRILTPEELLEFPQAGKPVNYLAKRFAAKEAFAKAVGTGIRGAVSFRNIGIGHDALGKPEFFYGPALSKWLEEQGISRVSLSMSDEEDTVLAFVVAEK 5suv C 1.75 BS02 COA C 1 D8 F26 R29 I30 E57 K61 G64 T65 G66 I67 F73 D8 F26 R29 I30 E57 K61 G64 T65 G66 I67 F73 2.7.8.7 A1KVH5 MIYGIGTDIVSLKRIIRLNKKFGQAFAGRILTPEELLEFPQAGKPVNYLAKRFAAKEAFAKAVGTGIRGAVSFRNIGIGHDALGKPEFFYGPALSKWLEEQGISRVSLSMSDEEDTVLAFVVAEK 5t2t A 1.97 BS02 MN A 2 I86 D88 I87 D89 2.7.7.48 A0A059U382 HDEIISELRELCLNYIEQDERLSRQKLNFLGQREPRMVLIEGLKLLSRCIEIDSADKSGCTHNHDDKSVETILVESGIVCPGLPLIIPDGYKLIDNSLILLECFVRSTPASFEKKFIEDTNKLACIREDLAVAGVTLVPIVDGRCDYDNSFMPEWANFKFRDLLFKLLEYSNQDEKVFEESEYFRLCES 5t2t A 1.97 BS03 0N8 A 1 K43 S46 R47 L84 I86 D88 C102 K114 K44 S47 R48 L85 I87 D89 C103 K115 2.7.7.48 A0A059U382 HDEIISELRELCLNYIEQDERLSRQKLNFLGQREPRMVLIEGLKLLSRCIEIDSADKSGCTHNHDDKSVETILVESGIVCPGLPLIIPDGYKLIDNSLILLECFVRSTPASFEKKFIEDTNKLACIREDLAVAGVTLVPIVDGRCDYDNSFMPEWANFKFRDLLFKLLEYSNQDEKVFEESEYFRLCES 5t5u A 1.80 BS01 MYA A 1 H146 Y147 V148 V210 I212 N213 F214 L215 C216 I217 R222 S223 K224 R225 L226 T227 P228 I231 T235 C238 Y239 Y244 A246 Y248 T249 L254 Y462 H46 Y47 V48 V110 I112 N113 F114 L115 C116 I117 R122 S123 K124 R125 L126 T127 P128 I131 T135 C138 Y139 Y144 A146 Y148 T149 L154 Y362 2.3.1.97 Q9UVX3 GGPIKIIDPEKVSKEPDALLEGFEWATLDLTNETELQELWDLLTYHYVEDDNAMFRFRYSQSFLHWALMSPGWKKEWHVGVRATKSRKLVASICGVPTEINVRNQKLKVVEINFLCIHKKLRSKRLTPVLIKEITRRCYLNGIYQAIYTAGVVLPTPVSSCRYYHRPLDWLKLYEVGFSPLPAGSTKARQITKNHLPSTTSTPGLRPMEPKDIDTVHDLLQRYLSRFALNQAFTREEVDHWLVHKPETVKEQVVWAYVVEDPETHKITDFFSFYNLESTVIQNPKHDNVRAAYLYYYATETAFTNNMKALKERLLMLMNDALILAKKAHFDVFNALTLHDNPLFLEQLKFGAGDGQLHFYLYNYRTAPVPGGVNEKNLPDEKRMGGVGIVML 5t5u A 1.80 BS02 75T A 1 D150 F155 R156 F157 Y263 H265 F278 S378 Y393 N434 L436 M491 L492 D50 F55 R56 F57 Y163 H165 F178 S278 Y293 N334 L336 M391 L392 2.3.1.97 Q9UVX3 GGPIKIIDPEKVSKEPDALLEGFEWATLDLTNETELQELWDLLTYHYVEDDNAMFRFRYSQSFLHWALMSPGWKKEWHVGVRATKSRKLVASICGVPTEINVRNQKLKVVEINFLCIHKKLRSKRLTPVLIKEITRRCYLNGIYQAIYTAGVVLPTPVSSCRYYHRPLDWLKLYEVGFSPLPAGSTKARQITKNHLPSTTSTPGLRPMEPKDIDTVHDLLQRYLSRFALNQAFTREEVDHWLVHKPETVKEQVVWAYVVEDPETHKITDFFSFYNLESTVIQNPKHDNVRAAYLYYYATETAFTNNMKALKERLLMLMNDALILAKKAHFDVFNALTLHDNPLFLEQLKFGAGDGQLHFYLYNYRTAPVPGGVNEKNLPDEKRMGGVGIVML 5t65 A 2.20 BS01 ILE A 1 Y101 F109 M111 M117 Y121 R126 W128 Y144 D146 A147 A148 I153 D173 Y72 F80 M82 M88 Y92 R97 W99 Y115 D117 A118 A119 I124 D144 G3XD24 NDYLQRNAIREDLESYLREMGDVTSSNIQNWLGGRLLLVEQTAQTLARDHSPETVSALLEQPALTSTFSFTYLGQQDGVFTMRPDSPMPAGYDPRSRPWYKDAVAAGGLTLTEPYVDAATQELIITAATPVKAAGNTLGVVGGDLSLKTLVQIINSLDFSGMGYAFLVSGDGKILVHPDKEQVMKTLSEVYPQNTPKIATGFSEAELHGHTRILAFTPIKGLPSVTWYLALSIDKDKAYA 5t65 B 2.20 BS01 ILE B 1 F99 Y101 M111 Y121 R126 W128 Y144 D146 A147 I153 D173 F65 Y67 M77 Y87 R92 W94 Y110 D112 A113 I119 D139 G3XD24 RNAIREDLESYLREMGDVTSSNIQNWLGGRLLLVEQTAQTLARDHSPETVSALLEQPALTSTFSFTYLGQQDGVFTMRPDSPMPAGYDPRSRPWYKDAVAAGGLTLTEPYVDAATQELIITAATPVKAAGNTLGVVGGDLSLKTLVQIINSLDFSGMGYAFLVSGDGKILVHPDKEQVMKTLSEVYPQNTPKIATGFSEAELHGHTRILAFTPIKGLPSVTWYLALSIDKDKAYAMLSK 5t6c A 1.90 BS02 75S A 1 V148 E149 D150 F155 R156 F157 T249 A250 G251 Y263 F278 S378 Y393 G455 Q456 L457 L492 V48 E49 D50 F55 R56 F57 T149 A150 G151 Y163 F178 S278 Y293 G355 Q356 L357 L392 2.3.1.97 Q9UVX3 GGPIKIIDPEKVSKEPDALLEGFEWATLDLTNETELQELWDLLTYHYVEDDNAMFRFRYSQSFLHWALMSPGWKKEWHVGVRATKSRKLVASICGVPTEINVRNQKLKVVEINFLCIHKKLRSKRLTPVLIKEITRRCYLNGIYQAIYTAGVVLPTPVSSCRYYHRPLDWLKLYEVGFSPLPAGSTKARQITKNHLPSTTSTPGLRPMEPKDIDTVHDLLQRYLSRFALNQAFTREEVDHWLVHKPETVKEQVVWAYVVEDPETHKITDFFSFYNLESTVIQNPKHDNVRAAYLYYYATETAFTNNMKALKERLLMLMNDALILAKKAHFDVFNALTLHDNPLFLEQLKFGAGDGQLHFYLYNYRTAPVPGGVNEKNLPDEKRMGGVGIVML 5t6e A 2.30 BS01 MYA A 1 H146 Y147 V148 I212 F214 L215 I217 R222 S223 K224 R225 L226 T227 I231 T235 C238 Y244 Q245 A246 Y248 T249 L254 Y462 H46 Y47 V48 I112 F114 L115 I117 R122 S123 K124 R125 L126 T127 I131 T135 C138 Y144 Q145 A146 Y148 T149 L154 Y362 2.3.1.97 Q9UVX3 GGPIKIIDPEKVSKEPDALLEGFEWATLDLTNETELQELWDLLTYHYVEDDNAMFRFRYSQSFLHWALMSPGWKKEWHVGVRATKSRKLVASICGVPTEINVRNQKLKVVEINFLCIHKKLRSKRLTPVLIKEITRRCYLNGIYQAIYTAGVVLPTPVSSCRYYHRPLDWLKLYEVGFSPLPAGSTKARQITKNHLPSTTSTPGLRPMEPKDIDTVHDLLQRYLSRFALNQAFTREEVDHWLVHKPETVKEQVVWAYVVEDPETHKITDFFSFYNLESTVIQNPKHDNVRAAYLYYYATETAFTNNMKALKERLLMLMNDALILAKKAHFDVFNALTLHDNPLFLEQLKFGAGDGQLHFYLYNYRTAPVPGGVNEKNLPDEKRMGGVGIVML 5t6e A 2.30 BS02 75R A 1 D150 F155 F157 T249 G251 Y263 H265 F278 S378 Y393 G455 L492 D50 F55 F57 T149 G151 Y163 H165 F178 S278 Y293 G355 L392 2.3.1.97 Q9UVX3 GGPIKIIDPEKVSKEPDALLEGFEWATLDLTNETELQELWDLLTYHYVEDDNAMFRFRYSQSFLHWALMSPGWKKEWHVGVRATKSRKLVASICGVPTEINVRNQKLKVVEINFLCIHKKLRSKRLTPVLIKEITRRCYLNGIYQAIYTAGVVLPTPVSSCRYYHRPLDWLKLYEVGFSPLPAGSTKARQITKNHLPSTTSTPGLRPMEPKDIDTVHDLLQRYLSRFALNQAFTREEVDHWLVHKPETVKEQVVWAYVVEDPETHKITDFFSFYNLESTVIQNPKHDNVRAAYLYYYATETAFTNNMKALKERLLMLMNDALILAKKAHFDVFNALTLHDNPLFLEQLKFGAGDGQLHFYLYNYRTAPVPGGVNEKNLPDEKRMGGVGIVML 5t6h A 1.80 BS02 75Q A 1 V148 E149 D150 F155 R156 F157 T249 G251 Y263 F278 G455 L457 L492 V48 E49 D50 F55 R56 F57 T149 G151 Y163 F178 G355 L357 L392 2.3.1.97 Q9UVX3 GGPIKIIDPEKVSKEPDALLEGFEWATLDLTNETELQELWDLLTYHYVEDDNAMFRFRYSQSFLHWALMSPGWKKEWHVGVRATKSRKLVASICGVPTEINVRNQKLKVVEINFLCIHKKLRSKRLTPVLIKEITRRCYLNGIYQAIYTAGVVLPTPVSSCRYYHRPLDWLKLYEVGFSPLPAGSTKARQITKNHLPSTTSTPGLRPMEPKDIDTVHDLLQRYLSRFALNQAFTREEVDHWLVHKPETVKEQVVWAYVVEDPETHKITDFFSFYNLESTVIQNPKHDNVRAAYLYYYATETAFTNNMKALKERLLMLMNDALILAKKAHFDVFNALTLHDNPLFLEQLKFGAGDGQLHFYLYNYRTAPVPGGVNEKNLPDEKRMGGVGIVML 5t99 A 2.40 BS01 GIF A 1 R186 H374 E442 E519 S522 W555 W578 F612 R131 H319 E387 E464 S467 W492 W515 F529 MASVTDGISFNENWRFFKGEIKGAEAISFDDDSWRKLNLPHDWAIEGPGLPFHGTGWYRKTFIGDAQWKDKIVRIGFDGAMSEAKVWINGVKVGEHPYGYTGFEIDITKYLKIGEENVLAVQLTPRDLSSRWYPGAGIYRNVWLRVDNKVYIPEHGVYVTTPTVTKSKAVVQIETTVKNATFGNGKFNIRHSIINAQGETVAILNDNVEVAAGEQGKTLAYINMLNPNIWGQKNPYMYKLKTEIYDGKDLTDTYFTDFGIRKICFTKDGFFLNGEKIRFNGVCLHHDNGPMGAAVNVRADERKLQIMKEMGVNAIRTSHNPPSPEFLDLCDRMGLVVLDEAFDEWTKAKVDNGYHLYFDEWSKKDLTSLIMRDRNHPSVIMWSIGNEILEQSDKKKGFTVAKYLADICRELDPTRPSTCGFNYYPAPFDNNMAQQVDIAGMNYKPGKYAEVQRLYPDLPLYGSETSSCTSSRGVYHLPTNQVTSYDLIGPKWAYPPDIEFHFQEMNPRFMGEFIWTGFDYLGESRSSYFGAVDLCGLPKDRFYLYQSQWTDKPMVHILPHWNWKKGMNIPVYVYTNCYEAELFLNGKSLGKRVKGRDLTEIMVNTFQSKYRLSWDVPFEPGELTVKAYNNLGELKAEKTIRTAGKPAQIKLIPDRKVITADGKDLSYITVRIEDRDGNLCPEADNLVEFSVEGAGHFRAVGNGNAATTESFIEPKRKAFSGMCMLIVQSDENKQGKMNITATSKGLKTAKTTINVEL 5t9g A 2.40 BS01 GIF A 1 R166 H355 N390 E436 E552 W575 E583 R135 H324 N359 E405 E514 W537 E545 SDFNNGWKFTLSDSVCYSFVNYNPSSWKTVNLPHDWSVDLPFESTAEGCTGFLKGGIGWYSKTFDTPDNFVDKKCYIVFDGVYNNSEYWINGRKLGFHPYGYSPFFYDISDYLNPKGQENRISVRIDHSRYADSRWYTGSGIYRETQLIFTDKLHIPVWGTFVTTPVVSSERATVNIEVRVKNDYSGPRAGEVRTSYFDSKNKKVGEKLTSFLIEAGKEMKINQSVEISNPSLWDVDSPSMYLAKSEILVDGNVVDTKETPFGIRSIKFDAKKGFFLNGKNMKIKGVCLHHDASMIGAALVEDVWRRRLQTLKDGGCNAIRLSHNPGADAFLELCDEMGFLVQEEFFDEWDYPKDKRLNMDEQSIDYITRGYCEYFQEWAERDLKNVMLRSRNHPCIFQWSIGNEIEWTYKGCKESTGFFYFWNQPPYSTQRIREEWAKQPKQTYDIGRTAKKLAAWTREMDTTRPVTANCILPSISYETGYIDALDVAGFSYRRVMYDYAHKNYPDKPAMGTENLGQWHEWKAVIERDYIPGMFIWTGVDYLGEVGTKGREWPQRAIGCGLLDLAGFEKPSFHMMKSLWTDAPFIAIYSQTANKSSYVEKDGKFTDKDPKKPWTQRLWVWEDVNSHWNYTKGEKVVVEIYSNCDEIELFQNGKSLGKRFLKDFEDHIYKWSVDFKDGNIVAKGKKNGKKTTSAIYTTKETNSIKLSVDKVAVDANNTDVIHVTAQLIDRNGRNISWEEKEITFNIGGNYRLLGVENGDHLNVLNYKSNTVKTYKGRALLVLQATDKAGILNINANSGSISSNDLKVEVK 5ta0 A 1.40 BS01 GAL A 1 G83 Q138 W374 G63 Q118 W354 QTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISQYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIRGI 5ta0 A 1.40 BS02 AAL A 1 H49 T82 Q138 N199 Q322 M369 H29 T62 Q118 N179 Q302 M349 QTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISQYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIRGI 5ta0 A 1.40 BS03 GAL A 2 E200 Q322 H384 E180 Q302 H364 QTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISQYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIRGI 5ta0 A 1.40 BS04 AAL A 2 E200 W203 F246 Q326 E180 W183 F226 Q306 QTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISQYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIRGI 5ta0 A 1.40 BS05 GAL A 3 W203 F246 F282 K285 Q326 H328 W183 F226 F262 K265 Q306 H308 QTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISQYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIRGI 5ta0 A 1.40 BS06 CA A 1 E200 P201 L202 W203 Y242 T244 A245 E180 P181 L182 W183 Y222 T224 A225 QTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISQYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIRGI 5ta0 A 1.40 BS07 CA A 2 Y242 F246 P247 D248 F249 R256 R260 Y222 F226 P227 D228 F229 R236 R240 QTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISQYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIRGI 5ta1 A 2.30 BS02 CA A 2 D430 N587 F588 G590 D411 N568 F569 G571 SQTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISEYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIRGI 5ta5 A 1.65 BS02 GAL A 1 W203 F246 K285 Q326 H328 W183 F226 K265 Q306 H308 QTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISEYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIR 5ta5 A 1.65 BS04 AAL A 2 H49 T82 Q138 F367 H29 T62 Q118 F347 QTHVQLNLNVKHKLGDVTEFNRPKFINFHATINENYWDSANKIADLRDDLIRKYDVYVGRETGMIKTVLRNVKEDPERPGFADPDDLARLCSQNKKRYVQNTKVHPYEKYSNLILCNQFSPFYPDGTKTLKGWALSQKDTEDEPFGTASGEFYGRYIKEYFGEGGESGEPKPGFCEVINEPLWDIYDKPKAPKSSITKLFEFHSTIAAQVKKFNPDMKVGGYCTAFPDFELQNFGRWNARWKQFIDIAGKDMDFFTIHLYDFPCKDGKQMYRKGSNMEATMDMIEQYSMIKLGEVKPLMISEYSAQTHDYNRKPWSPYRDWLRLKSTNSMLMQFMERTDNICYAMPFAMLKSEWGYNPKTGLAHTARMLRRENEPESFTGEYVYSELIKFYQLWKDVKGTRVETNCDNPDIMCDAYVDGKNVYFIINNLDFKPVDLNLSVNGTSKDAKSIEVRHLYLKGGKDGVPILDVYDAKSLDHFTLETEATCVICYNFDRKVKINETMEEVKYYATDYLKEIAAGKELVFNINNVKKTEYGEAVIRLGLGRNHGLSLLPELLVNGKKVDIPDNFRGDVQKDRASFFGVIEVPVDYSILKGNNTISLKFPDNGGHVSTVTMQIFNFSNNIR 5ta9 A 2.40 BS01 GAL A 1 F125 K260 E262 R273 H302 F92 K227 E229 R240 H269 YDQRKADSLGIPKGNKLSAAMKRAMEWPQRDNSWFFEYKMMPLKGDLAYEEGIVRRDPSAMIKVGDKYYVWYSKSYGETQGFAGDVENEKVFPWDRCDIWYATSKDGITWKEEGVAVKRGEKGAYDDRSVFTPEVMQWNGKYYLCYQTVKSPYTVRVKENVAMAWADSPDGPWEKTDKPVLTPSDNGVWEGEEDNRFKVKAKGDFDSHKVHDPCIIPYNGKFYLYYKGERMGEEITWGGREIKHGVAIADNPLGPYTKSEYNPISNSGHEICVWPYKGGIASLITTDGPEKNTLQWSPDGINFEIMSVIPGAPHAIGLNRSADNDKEPTEILRWGLTHQYITYNYQCIMRFETWTKQTHTAIGESTKRK 5ta9 A 2.40 BS02 AAL A 1 W127 T165 Q180 H244 D245 K260 E303 W94 T132 Q147 H211 D212 K227 E270 YDQRKADSLGIPKGNKLSAAMKRAMEWPQRDNSWFFEYKMMPLKGDLAYEEGIVRRDPSAMIKVGDKYYVWYSKSYGETQGFAGDVENEKVFPWDRCDIWYATSKDGITWKEEGVAVKRGEKGAYDDRSVFTPEVMQWNGKYYLCYQTVKSPYTVRVKENVAMAWADSPDGPWEKTDKPVLTPSDNGVWEGEEDNRFKVKAKGDFDSHKVHDPCIIPYNGKFYLYYKGERMGEEITWGGREIKHGVAIADNPLGPYTKSEYNPISNSGHEICVWPYKGGIASLITTDGPEKNTLQWSPDGINFEIMSVIPGAPHAIGLNRSADNDKEPTEILRWGLTHQYITYNYQCIMRFETWTKQTHTAIGESTKRK 5ta9 B 2.40 BS01 GAL B 1 W127 K260 E262 R273 H302 W94 K227 E229 R240 H269 YDQRKADSLGIPKGNKLSAAMKRAMEWPQRDNSWFFEYKMMPLKGDLAYEEGIVRRDPSAMIKVGDKYYVWYSKSYGETQGFAGDVENEKVFPWDRCDIWYATSKDGITWKEEGVAVKRGEKGAYDDRSVFTPEVMQWNGKYYLCYQTVKSPYTVRVKENVAMAWADSPDGPWEKTDKPVLTPSDNGVWEGEEDNRFKVKAKGDFDSHKVHDPCIIPYNGKFYLYYKGERMGEEITWGGREIKHGVAIADNPLGPYTKSEYNPISNSGHEICVWPYKGGIASLITTDGPEKNTLQWSPDGINFEIMSVIPGAPHAIGLNRSADNDKEPTEILRWGLTHQYITYNYQCIMRFETWTKQTHTAIGESTKRK 5ta9 B 2.40 BS02 AAL B 1 R89 W127 T165 Q180 H244 D245 K260 H302 E303 R56 W94 T132 Q147 H211 D212 K227 H269 E270 YDQRKADSLGIPKGNKLSAAMKRAMEWPQRDNSWFFEYKMMPLKGDLAYEEGIVRRDPSAMIKVGDKYYVWYSKSYGETQGFAGDVENEKVFPWDRCDIWYATSKDGITWKEEGVAVKRGEKGAYDDRSVFTPEVMQWNGKYYLCYQTVKSPYTVRVKENVAMAWADSPDGPWEKTDKPVLTPSDNGVWEGEEDNRFKVKAKGDFDSHKVHDPCIIPYNGKFYLYYKGERMGEEITWGGREIKHGVAIADNPLGPYTKSEYNPISNSGHEICVWPYKGGIASLITTDGPEKNTLQWSPDGINFEIMSVIPGAPHAIGLNRSADNDKEPTEILRWGLTHQYITYNYQCIMRFETWTKQTHTAIGESTKRK 5ta9 C 2.40 BS01 GAL C 1 K260 E262 R273 H302 K227 E229 R240 H269 YDQRKADSLGIPKGNKLSAAMKRAMEWPQRDNSWFFEYKMMPLKGDLAYEEGIVRRDPSAMIKVGDKYYVWYSKSYGETQGFAGDVENEKVFPWDRCDIWYATSKDGITWKEEGVAVKRGEKGAYDDRSVFTPEVMQWNGKYYLCYQTVKSPYTVRVKENVAMAWADSPDGPWEKTDKPVLTPSDNGVWEGEEDNRFKVKAKGDFDSHKVHDPCIIPYNGKFYLYYKGERMGEEITWGGREIKHGVAIADNPLGPYTKSEYNPISNSGHEICVWPYKGGIASLITTDGPEKNTLQWSPDGINFEIMSVIPGAPHAIGLNRSADNDKEPTEILRWGLTHQYITYNYQCIMRFETWTKQTHTAIGESTKRK 5ta9 C 2.40 BS02 AAL C 1 R89 D90 W127 F164 T165 Q180 E192 H244 D245 K260 E303 R56 D57 W94 F131 T132 Q147 E159 H211 D212 K227 E270 YDQRKADSLGIPKGNKLSAAMKRAMEWPQRDNSWFFEYKMMPLKGDLAYEEGIVRRDPSAMIKVGDKYYVWYSKSYGETQGFAGDVENEKVFPWDRCDIWYATSKDGITWKEEGVAVKRGEKGAYDDRSVFTPEVMQWNGKYYLCYQTVKSPYTVRVKENVAMAWADSPDGPWEKTDKPVLTPSDNGVWEGEEDNRFKVKAKGDFDSHKVHDPCIIPYNGKFYLYYKGERMGEEITWGGREIKHGVAIADNPLGPYTKSEYNPISNSGHEICVWPYKGGIASLITTDGPEKNTLQWSPDGINFEIMSVIPGAPHAIGLNRSADNDKEPTEILRWGLTHQYITYNYQCIMRFETWTKQTHTAIGESTKRK 5ta9 D 2.40 BS01 GAL D 1 F125 W127 K260 E262 R273 H302 F92 W94 K227 E229 R240 H269 YDQRKADSLGIPKGNKLSAAMKRAMEWPQRDNSWFFEYKMMPLKGDLAYEEGIVRRDPSAMIKVGDKYYVWYSKSYGETQGFAGDVENEKVFPWDRCDIWYATSKDGITWKEEGVAVKRGEKGAYDDRSVFTPEVMQWNGKYYLCYQTVKSPYTVRVKENVAMAWADSPDGPWEKTDKPVLTPSDNGVWEGEEDNRFKVKAKGDFDSHKVHDPCIIPYNGKFYLYYKGERMGEEITWGGREIKHGVAIADNPLGPYTKSEYNPISNSGHEICVWPYKGGIASLITTDGPEKNTLQWSPDGINFEIMSVIPGAPHAIGLNRSADNDKEPTEILRWGLTHQYITYNYQCIMRFETWTKQTHTAIGESTKRK 5tt3 A 2.20 BS02 EZL A 1 H110 H112 H129 L190 T191 A192 P193 W201 H89 H91 H108 L166 T167 A168 P169 W177 A0A0M3KL20 28002963 KWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tt3 B 2.20 BS02 EZL B 1 H110 H112 H129 V141 L190 T191 A192 P193 W201 H82 H84 H101 V113 L155 T156 A157 P158 W166 A0A0M3KL20 28002963 KWDYKNHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAVFFHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tt3 F 2.20 BS02 EZL F 1 H110 H112 V131 V141 L190 T191 P193 W201 H88 H90 V109 V119 L163 T164 P166 W174 A0A0M3KL20 28002963 WDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tt3 G 2.20 BS02 EZL G 1 H110 H112 H129 V131 V141 L190 T191 P193 W201 H87 H89 H106 V108 V118 L161 T162 P164 W172 A0A0M3KL20 28002963 TKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQLDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tt3 H 2.20 BS02 EZL H 1 H110 H112 V131 L190 T191 P193 H88 H90 V109 L166 T167 P169 A0A0M3KL20 28002963 WDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tt8 A 2.40 BS02 D8W A 1 K88 D107 N108 H110 H112 H129 V131 V141 L190 T191 W201 K58 D77 N78 H80 H82 H99 V101 V104 L146 T147 W157 A0A0M3KL20 28002963 ENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHLVLAIGFEEGKENPNLDPILNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAE 5tt8 B 2.40 BS02 D8W B 1 K88 N108 H110 H112 H129 V131 L190 T191 W201 K65 N85 H87 H89 H106 V108 L164 T165 W175 A0A0M3KL20 28002963 TKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tt8 C 2.40 BS02 D8W C 1 D107 N108 H110 H112 K133 L139 L190 T191 A192 W201 D87 N88 H90 H92 K113 L119 L170 T171 A172 W181 A0A0M3KL20 28002963 TKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tt8 D 2.40 BS01 ZN D 1 H110 H112 H129 H82 H84 H101 A0A0M3KL20 28002963 KENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFKENPNLDPILNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSASPNQRPVQPDYNTVIIKSSAET 5tt8 D 2.40 BS02 D8W D 1 K88 D107 N108 H110 H112 K133 L190 T191 A192 K60 D79 N80 H82 H84 K105 L152 T153 A154 A0A0M3KL20 28002963 KENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFKENPNLDPILNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSASPNQRPVQPDYNTVIIKSSAET 5tt8 E 2.40 BS02 D8W E 1 K88 D107 N108 H110 H112 H129 L190 T191 A192 K65 D84 N85 H87 H89 H106 L167 T168 A169 A0A0M3KL20 28002963 KWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tt8 G 2.40 BS02 D8W G 1 K88 D107 N108 H110 H112 V131 L190 T191 K66 D85 N86 H88 H90 V108 L160 T161 A0A0M3KL20 28002963 NTKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tt8 H 2.40 BS02 D8W H 1 K88 D107 N108 H110 H112 H129 V141 L190 T191 A192 W201 K64 D83 N84 H86 H88 H105 V117 L166 T167 A168 W177 A0A0M3KL20 28002963 WDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo A 2.50 BS02 1SA A 1 H84 T86 H110 H112 H129 L190 T191 A192 H61 T63 H87 H89 H106 L167 T168 A169 4.2.1.1 A0A0M3KL20 28002963 TKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo B 2.50 BS02 1SA B 1 H110 H112 H129 V131 L190 T191 A192 H87 H89 H106 V108 L160 T161 A162 4.2.1.1 A0A0M3KL20 28002963 KWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo C 2.50 BS02 1SA C 1 T83 H84 T86 H110 H112 H129 L190 T191 A192 T62 H63 T65 H89 H91 H108 L169 T170 A171 4.2.1.1 A0A0M3KL20 28002963 KWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo D 2.50 BS02 1SA D 1 W23 T83 H84 H110 H112 L190 T191 A192 W1 T58 H59 H85 H87 L163 T164 A165 4.2.1.1 A0A0M3KL20 28002963 WDYKNENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKKNSPNQRPVQPDYNTVIIKSSAETR 5tuo E 2.50 BS02 1SA E 1 H110 H112 H129 V131 L190 T191 A192 W201 H91 H93 H110 V112 L171 T172 A173 W182 4.2.1.1 A0A0M3KL20 28002963 NTKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo F 2.50 BS02 1SA F 1 H110 H112 H129 L190 T191 A192 H83 H85 H99 L151 T152 A153 4.2.1.1 A0A0M3KL20 28002963 WDYENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKLSAHFVHKDAKGRLLVLAIGFENPNLDPILEGIQKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIVSAKQLAEIKKRMPNQRPVQPDYNTVIIKSSAET 5tuo G 2.50 BS02 1SA G 1 H110 H112 H129 L190 T191 H88 H90 H107 L168 T169 4.2.1.1 A0A0M3KL20 28002963 TKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo H 2.50 BS02 1SA H 1 W23 H84 T86 H110 H112 L190 T191 A192 W1 H60 T62 H86 H88 L161 T162 A163 4.2.1.1 A0A0M3KL20 28002963 WDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5u1m A 1.80 BS01 III B 1 L208 M209 I211 R212 R213 C214 G215 H216 S217 F222 G226 R227 H250 L254 M257 S261 L48 M49 I51 R52 R53 C54 G55 H56 S57 F62 G66 R67 H90 L94 M97 S101 P35568 28345670 KEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDAFR 5ue3 A 1.60 BS04 CA A 2 S129 E130 D206 S89 E90 D166 3.4.24.35 P14780 28860188 DRQLAEEYLYRYGYTRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY 5ue3 A 1.60 BS05 CA A 3 A164 D165 G197 I198 Q199 D201 A124 D125 G157 I158 Q159 D161 3.4.24.35 P14780 28860188 DRQLAEEYLYRYGYTRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY 5ue4 A 1.80 BS05 CA A 3 S129 D131 D206 E208 L209 W210 S88 D90 D165 E167 L168 W169 3.4.24.35 P14780 28860188 TDRQLAEEYLYRYGYTRVAEMRGESLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY 5ue4 B 1.80 BS05 5XQ B 1 V101 P102 R106 F110 L114 Y179 H190 A191 F192 P193 H230 G233 L234 V55 P56 R60 F61 L65 Y130 H141 A142 F143 P144 H181 G184 L185 3.4.24.35 P14780 28860188 DRQLAEEYLYRYGYTRVAESLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYG 5uqd A 1.80 BS01 AKG A 1 W1410 T1449 H1452 D1454 A1499 K1526 Y1585 L1587 H1593 F1595 W189 T206 H209 D211 A220 K240 Y299 L301 H307 F309 Q9GRZ3 28867287 NATMRITNRNLKMLTRQFDLPKMSSRFRKFVRIRRHPNGMATIISCDYNQIKQHLGPNEMKHFERQFVRLGFAENNGVPLFAIGVMENAAEALHDQFEWLAKNSPNTQVKVGSLTNKQFIETMPMKKYYESAMETLDMGTFRFGPLMSLSMVGNFKEMLDALNAAPFLGPIMPWGDFSEVTSDDGPIFWVRPGEQMVPETAFNDRTNAHADQVRVKSTAAVGVLQGIRNPYYEDERKAVKEVIVFDAHDLHKVAHHLAMDLYEPPVSQCHRWVDDAILNTMRREGIRYAKLELHENDMYFLPRNVIHQFRTVSACSSVAWHVRL 5uqd A 1.80 BS02 FE2 A 1 H1452 D1454 H1593 H209 D211 H307 Q9GRZ3 28867287 NATMRITNRNLKMLTRQFDLPKMSSRFRKFVRIRRHPNGMATIISCDYNQIKQHLGPNEMKHFERQFVRLGFAENNGVPLFAIGVMENAAEALHDQFEWLAKNSPNTQVKVGSLTNKQFIETMPMKKYYESAMETLDMGTFRFGPLMSLSMVGNFKEMLDALNAAPFLGPIMPWGDFSEVTSDDGPIFWVRPGEQMVPETAFNDRTNAHADQVRVKSTAAVGVLQGIRNPYYEDERKAVKEVIVFDAHDLHKVAHHLAMDLYEPPVSQCHRWVDDAILNTMRREGIRYAKLELHENDMYFLPRNVIHQFRTVSACSSVAWHVRL 5v4a A 1.75 BS01 UDP A 1 R27 Y43 S115 R116 G148 S151 P172 S173 R174 N175 A176 M199 L200 G201 K205 G222 H223 H245 R23 Y39 S111 R112 G144 S147 P168 S169 R170 N171 A172 M195 L196 G197 K201 G218 H219 H241 A3CM53 QISVLSINQSLDYLLEKGASVVRFGDGEMDLVAGRSIVYQDFDPELSARLREIMSMESDERLMVCLPDVFTGLERYSIDAQNFWSLNHLPHFLEKYKNICRAPWYGSTFISRPYIDLEDKTPSVGYFAKLKQLWQDKDLLIVEGLTSRSGVGNDLFDGARSIKRIICPSRNAYSKLEAIKQAVREHADNRLILTMLGPTAKVLVYDLVQEGYRALDIGHIDSEYEWFQMGASHKVKLSHKHTAEHNFDQDIEFRDDQAYDSQIVANLA 5v4y A 1.90 BS01 8FM A 1 D25 G27 A28 D29 D30 G48 G49 P81 V82 I84 D25 G27 A28 D29 D30 G48 G49 P81 V82 I84 Q72874 PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF 5vaj A 1.95 BS01 NUC C 1 D71 V72 S74 Q75 G76 N77 N105 E109 N132 Q134 K180 T183 D10 V11 S13 Q14 G15 N16 N44 E48 N71 Q73 K119 T122 3.1.26.4 Q9KEI9 28854734 EIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEFLAIVHGLRYLKERNSRKPIYSNSQTAIKWVKDKKAKSTLVRNEETALIWKLVDEAEEWLNTHTYETPILKWQTDKWGEIKADYGRK 5vaj B 1.95 BS01 NUC C 1 D71 V72 G73 S74 Q75 G76 N105 E109 N132 Q134 K180 T183 D13 V14 G15 S16 Q17 G18 N47 E51 N74 Q76 K122 T125 3.1.26.4 Q9KEI9 28854734 AKEEIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEFLAIVHGLRYLKERNSRKPIYSNSQTAIKWVKDKKAKSTLVRNEETALIWKLVDEAEEWLNTHTYETPILKWQTDKWGEIKADYG 5vf3 A 3.30 BS01 III Z 1 Q335 P337 Q270 P272 P04535 AEIGGDHGYNATNIAAGQTSGAVTQIGPAVMGMVRRAIPNLIAFDICGVQPMNSPTGQVFALRAVYGKDPVAAGAKEAFHPMYGPDAMFSGQGAAKKFPALAASTQTTVGDIYTHFFQETGTVYLQASVQVTIDAGATDAAKLDAEIKKQMEAGALVEIAEGMATSIAELQEGFNGSTDNPWNEMGFRIDKQVIEAKSRQLKAAYSIELTQDLRAVHGMDADAELSGILATEIMLEINREVVDWINYSAQVGKSGMTLTPGSKAGVFDFQDPIDIRGARWAGESFKALLFQIDKEAVEIARQTGRGEGNFIIASRNVVNVLASVDTGISYAAQGLATGFSTDTTKSVFAGVLGGKYRVYIDQYAKQDYFTVGYKGPNEMDAGIYYAPYVALTPLRGSDPKNFQPVMGFKTRYGIGINPFAESAAQAPASRIQSGMPSILNSLGKNAYFRRVYVKGI 5vf3 B 3.30 BS01 III Z 1 P337 G342 A343 P272 G277 A278 P04535 AEIGGDHGYNATNIAAGQTSGAVTQIGPAVMGMVRRAIPNLIAFDICGVQPMNSPTGQVFALRAVYGKDPVAAGAKEAFHPMYGPDAMFSGQGAAKKFPALAASTQTTVGDIYTHFFQETGTVYLQASVQVTIDAGATDAAKLDAEIKKQMEAGALVEIAEGMATSIAELQEGFNGSTDNPWNEMGFRIDKQVIEAKSRQLKAAYSIELTQDLRAVHGMDADAELSGILATEIMLEINREVVDWINYSAQVGKSGMTLTPGSKAGVFDFQDPIDIRGARWAGESFKALLFQIDKEAVEIARQTGRGEGNFIIASRNVVNVLASVDTGISYAAQGLATGFSTDTTKSVFAGVLGGKYRVYIDQYAKQDYFTVGYKGPNEMDAGIYYAPYVALTPLRGSDPKNFQPVMGFKTRYGIGINPFAESAAQAPASRIQSGMPSILNSLGKNAYFRRVYVKGI 5vf3 C 3.30 BS01 III z 1 G342 A343 R344 G277 A278 R279 P04535 AEIGGDHGYNATNIAAGQTSGAVTQIGPAVMGMVRRAIPNLIAFDICGVQPMNSPTGQVFALRAVYGKDPVAAGAKEAFHPMYGPDAMFSGQGAAKKFPALAASTQTTVGDIYTHFFQETGTVYLQASVQVTIDAGATDAAKLDAEIKKQMEAGALVEIAEGMATSIAELQEGFNGSTDNPWNEMGFRIDKQVIEAKSRQLKAAYSIELTQDLRAVHGMDADAELSGILATEIMLEINREVVDWINYSAQVGKSGMTLTPGSKAGVFDFQDPIDIRGARWAGESFKALLFQIDKEAVEIARQTGRGEGNFIIASRNVVNVLASVDTGISYAAQGLATGFSTDTTKSVFAGVLGGKYRVYIDQYAKQDYFTVGYKGPNEMDAGIYYAPYVALTPLRGSDPKNFQPVMGFKTRYGIGINPFAESAAQAPASRIQSGMPSILNSLGKNAYFRRVYVKGI 5w0c A 2.00 BS01 HEM A 1 R97 I112 V113 W120 L294 A297 G298 T301 T302 T305 L361 L362 S365 L366 H368 P427 F428 S429 R433 C435 V436 G437 A441 R71 I86 V87 W94 L268 A271 G272 T275 T276 T279 L335 L336 S339 L340 H342 P401 F402 S403 R407 C409 V410 G411 A415 1.14.13.-,1.14.13.80,1.14.13.48,1.14.13.49,1.14.99.38 P11712 28815830 GKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPI 5w0c A 2.00 BS02 9W6 A 1 F100 L102 A103 A106 R108 V113 F114 L208 L233 V237 G296 A297 L366 F476 F74 L76 A77 A80 R82 V87 F88 L182 L207 V211 G270 A271 L340 F450 1.14.13.-,1.14.13.80,1.14.13.48,1.14.13.49,1.14.99.38 P11712 28815830 GKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPI 5w1h A 1.99 BS01 NUC B 1 K14 T16 T21 A22 V23 R127 R189 R231 A232 Q235 V236 R238 S239 N242 M243 N244 M245 S260 T264 S266 R270 K274 R332 R369 I373 Y376 R377 H403 R404 E406 Y407 E410 K411 K417 F422 K423 K432 Y440 I443 K444 K450 S483 Y486 E487 K490 K639 S642 R668 Q671 V672 P673 S674 N676 K677 V680 N683 L711 N715 Y719 K722 Y726 M810 Y813 N814 C820 M821 Q822 K823 K840 M841 A913 N916 Q927 Y928 D931 V968 G972 T973 R1036 Q1076 I1090 F1093 Q1094 K1097 N1098 R1103 R1128 F1267 D1268 K1276 Y1277 R1278 K1279 N1280 P1282 I1284 N1287 F1293 F1300 S1302 K1305 K1320 E1321 C1322 A1323 F1338 T1339 Y1340 K1341 R1352 K1 T3 T8 A9 V10 R108 R170 R212 A213 Q216 V217 R219 S220 N223 M224 N225 M226 S241 T245 S247 R251 K255 R313 R345 I349 Y352 R353 H379 R380 E382 Y383 E386 K387 K393 F398 K399 K408 Y416 I419 K420 K426 S459 Y462 E463 K466 K613 S616 R642 Q645 V646 P647 S648 N650 K651 V654 N657 L683 N687 Y691 K694 Y698 M753 Y756 N757 C758 M759 Q760 K761 K766 M767 A839 N842 Q853 Y854 D857 V894 G898 T899 R962 Q1002 I1016 F1019 Q1020 K1023 N1024 R1029 R1054 F1193 D1194 K1202 Y1203 R1204 K1205 N1206 P1208 I1210 N1213 F1219 F1226 S1228 K1231 K1243 E1244 C1245 A1246 F1261 T1262 Y1263 K1264 R1275 KLTVNAKTAVVSENRSQEGILYNDPSRYGKSRKNDEDRDRYIESRLKSSGKLYRIFNETDELQWFLSEIVKKINRRNGLVLSDMLSVDDRAFEKAFEKYAELSYTNRRNKVSGSPAFETCGVDAATAERLKGIISETNFINRIKNNIDNKVSEDIIDRIIAKYLKKSLCRERVKRGLKKLLMNAFDLPYSDPDIDVQRDFIDYVLEDFYHVRAKSQVSRSIKNMNMPVQPEGDGKFAITVSKGGTESGNKRSAEKEAFKKFLSDYASLDERVRDDMLRRMRRLVVLYFYGSDDSKLSDVNEKFDVWEDHAARRVDNREFIKLPLENKTDKDAERIRKNTVKELYRNQNIGCYRQAVKAVEEDNNGRYFDDKMLNMFFIHRIEYGVEKIYANLKQVTEFKARTGYLSEKIWKDLINYISIKYIAMGKAVYNYAMDELNASDKKEIELGKISEEYLSGISSFDYELIKAEEMLQRETAVYVAFAARHLSSQTVELDSENSDFLLLKPKGTMDKNDKNKLASNNILNFLKDKETLRDTILQYFGGHSLWTDFPFDKYLAGGKDDVDFLTDLKDVIYSMRNDSFHYATHNNGKWNKELISAMFEHETERMTVVMKDKFYSNNLPMFYKNDDLKKLLIDLYKDNVERASQVPSFNKVFVRKNFPALVRDKDNLGIELDLDADKGENELKFYNALYYMFKEIYYNAFLNDKNVRERFITKATKVADNNYIAENDFGQRIKNIVQVNPDYTLAQICQLIMTEYNCMQKKSAYKMLLLVNLRKAFLEFIKENYAFVLKPYKHDLCDKADFVPDFAKYVKPYAGLISRVAGSSELQKWYIVSRFLSPAQANHMLGFLHSYKQYVWDIYRRASETGTEINHSIAEDKIAGVDITDVDAVIDLSVKLCGTISSEISDYFKDDEVYAEYISSYLDFEYDGGNYKDSLNRFCNSDAVNDQKVALYYDGEHPKLNRNIILSKLYGERRFLEKITDRVSRSDIVEYYKLKKETSQYQTKGIFDSEDEQKNIKKFQEMKNIVEFRDLMDYSEIADELQGQLINWIYLRERDLMNFQLGYHYACLNNDSNKQATYVTLDYQGKKNRKINGAILYQICAMYINGLPLYYVDKDSSEWTVSDGKESTGAKIGEFYRYAKSFENTSDCYASGLEIFENISEHDNITELRNYIEHFRYYSSFDRSFLGIYSEVFDRFFTYDLKYRKNVPTILYNILLQHFVNVRFEFVSGKKMIGIDKKIAKEKECARITIREKNGVYSEQFTYKLKNGTVYVDARDKRYLQSIIRLLFYPEKVNMDEMIEV 5w1i A 2.20 BS01 NUC B 1 K14 L15 T16 T21 A22 V23 R127 R189 R231 A232 Q235 V236 R238 S239 I240 N242 M243 N244 M245 S260 T264 S266 R270 K274 R332 R369 I373 Y376 R377 H403 R404 E406 Y407 E410 K411 K417 F422 K423 K432 Y440 I443 K444 K450 S483 Y486 E487 K490 M494 K639 S642 N643 R668 Q671 V672 S674 N676 K677 V680 K682 N683 L711 N715 Y719 K722 Y726 N814 C820 M821 K823 K840 N916 Q927 Y928 D931 V968 G972 T973 R1036 Q1076 I1090 F1093 Q1094 K1097 R1128 F1267 D1268 K1276 Y1277 R1278 K1279 N1280 P1282 I1284 N1287 H1292 F1293 F1300 S1302 K1320 E1321 C1322 A1323 F1338 T1339 Y1340 K1341 R1352 K1 L2 T3 T8 A9 V10 R107 R169 R211 A212 Q215 V216 R218 S219 I220 N222 M223 N224 M225 S240 T244 S246 R250 K254 R312 R343 I347 Y350 R351 H377 R378 E380 Y381 E384 K385 K391 F396 K397 K406 Y414 I417 K418 K424 S457 Y460 E461 K464 M468 K610 S613 N614 R639 Q642 V643 S645 N647 K648 V651 K653 N654 L678 N682 Y686 K689 Y693 N752 C753 M754 K756 K762 N838 Q849 Y850 D853 V890 G894 T895 R958 Q998 I1012 F1015 Q1016 K1019 R1050 F1186 D1187 K1195 Y1196 R1197 K1198 N1199 P1201 I1203 N1206 H1211 F1212 F1219 S1221 K1236 E1237 C1238 A1239 F1254 T1255 Y1256 K1257 R1268 KLTVNAKTAVVSENRSQEGILYNDPSRYGKSRKNDEDRDRYIESRLKSSGKLYRIFNEDELQWFLSEIVKKINRRNGLVLSDMLSVDDRAFEKAFEKYAELSYTNRRNKVSGSPAFETCGVDAATAERLKGIISETNFINRIKNNIDNKVSEDIIDRIIAKYLKKSLCRERVKRGLKKLLMNAFDLPYSDPDIDVQRDFIDYVLEDFYHVRAKSQVSRSIKNMNMPVQPEGDGKFAITVSKGGTESGNKRSAEKEAFKKFLSDYASLDERVRDDMLRRMRRLVVLYFYGSDDSKLSDVNEKFDVWEDHAARRVDNREFIKLPLENTDKDAERIRKNTVKELYRNQNIGCYRQAVKAVEEDNNGRYFDDKMLNMFFIHRIEYGVEKIYANLKQVTEFKARTGYLSEKIWKDLINYISIKYIAMGKAVYNYAMDELNASDKKEIELGKISEEYLSGISSFDYELIKAEEMLQRETAVYVAFAARHLSSQTVELDSENSDFLLLKPKGTMDKNDKNKLASNNILNFLKDKETLRDTILQYFGGHSLWTDFPFDKYLAGGKDDVDFLTDLKDVIYSMRNDSFHYATNNGKWNKELISAMFEHETERMTVVMKDKFYSNNLPMFYKNDDLKKLLIDLYKDNVERASQVPSFNKVFVRKNFPALVRDKDNLGIELDLDKGENELKFYNALYYMFKEIYYNAFLNDKNVRERFITKATKVADNNYIAENDFGQRIKNIVQVNPDYTLAQICQLIMTEYNCMQKKSAHYKMLLLVNLRKAFLEFIKENYAFVLKPYKHDLCDKADFVPDFAKYVKPYAGLISRVAGSSELQKWYIVSRFLSPAQANHMLGFLHSYKQYVWDIYRRASETGTEINHSIAEDKIAGVDITDVDAVIDLSVKLCGTISSEISDYFKDDEVYAEYISSYLDFEYDGGNYKDSLNRFCNSDAVNDQKVALYYDGEHPKLNRNIILSKLYGERRFLEKITDRVSRSDIVEYYKLKKETSQYQTKGIFDSEDEQKNIKKFQEMKNIVEFRDLMDYSEIADELQGQLINWIYLRERDLMNFQLGYHYACLNNDSNKQATYVTLDYQGKKNRKINGAILYQICAMYINGLPLYYVDKDSSEWTVSDGKESTGAKIGEFYRYAKSFSDCYASGLEIFENISEHDNITELRNYIEHFRYYSSFDRSFLGIYSEVFDRFFTYDLKYRKNVPTILYNILLQHFVNVRFEFVSGKKMIGIDKKIAKEKECARITIREKNGVYSEQFTYKLKNGTVYVDARDKRYLQSIIRLLFYPEKVNMDEMIEV 5w1i C 2.20 BS01 NUC D 1 K14 L15 T16 T21 A22 V23 R127 K129 R189 R231 A232 V236 R238 S239 I240 N242 M243 N244 M245 S260 T264 S266 R270 K274 R332 R369 I373 Y376 R377 H403 R404 E406 Y407 E410 K411 K417 F422 K423 K432 Y440 I443 K444 K450 S483 Y486 E487 K490 K639 R668 Q671 V672 S674 N676 K677 V680 N683 Y719 K722 Y726 C820 M821 Q822 K823 A913 N916 Q927 Y928 D931 V968 G972 R1036 R1103 R1128 F1267 D1268 K1276 Y1277 R1278 K1279 N1280 P1282 I1284 N1287 H1292 F1293 F1300 S1302 K1305 K1320 E1321 C1322 A1323 F1338 T1339 Y1340 K1341 R1352 K1 L2 T3 T8 A9 V10 R108 K110 R170 R212 A213 V217 R219 S220 I221 N223 M224 N225 M226 S241 T245 S247 R251 K255 R313 R345 I349 Y352 R353 H379 R380 E382 Y383 E386 K387 K393 F398 K399 K408 Y416 I419 K420 K426 S459 Y462 E463 K466 K613 R642 Q645 V646 S648 N650 K651 V654 N657 Y691 K694 Y698 C758 M759 Q760 K761 A840 N843 Q854 Y855 D858 V895 G899 R963 R1028 R1053 F1190 D1191 K1199 Y1200 R1201 K1202 N1203 P1205 I1207 N1210 H1215 F1216 F1223 S1225 K1228 K1240 E1241 C1242 A1243 F1258 T1259 Y1260 K1261 R1272 KLTVNAKTAVVSENRSQEGILYNDPSRYGKSRKNDEDRDRYIESRLKSSGKLYRIFNETDELQWFLSEIVKKINRRNGLVLSDMLSVDDRAFEKAFEKYAELSYTNRRNKVSGSPAFETCGVDAATAERLKGIISETNFINRIKNNIDNKVSEDIIDRIIAKYLKKSLCRERVKRGLKKLLMNAFDLPYSDPDIDVQRDFIDYVLEDFYHVRAKSQVSRSIKNMNMPVQPEGDGKFAITVSKGGTESGNKRSAEKEAFKKFLSDYASLDERVRDDMLRRMRRLVVLYFYGSDDSKLSDVNEKFDVWEDHAARRVDNREFIKLPLENKTDKDAERIRKNTVKELYRNQNIGCYRQAVKAVEEDNNGRYFDDKMLNMFFIHRIEYGVEKIYANLKQVTEFKARTGYLSEKIWKDLINYISIKYIAMGKAVYNYAMDELNASDKKEIELGKISEEYLSGISSFDYELIKAEEMLQRETAVYVAFAARHLSSQTVELDSENSDFLLLKPKGTMDKNDKNKLASNNILNFLKDKETLRDTILQYFGGHSLWTDFPFDKYLAGGKDDVDFLTDLKDVIYSMRNDSFHYATHNNGKWNKELISAMFEHETERMTVVMKDKFYSNNLPMFYKNDDLKKLLIDLYKDNVERASQVPSFNKVFVRKNFPALVRDKDNLGIELDLDADKGENELKFYNALYYMFKEIYYNAFLNDKNVRERFITKATKVADNNYIAENDFGQRIKNIVQVNPDYTLAQICQLIMTEYNCMQKKSAHYKMLLLVNLRKAFLEFIKENYAFVLKPYKHDLCDKADFVPDFAKYVKPYAGLISRVAGSSELQKWYIVSRFLSPAQANHMLGFLHSYKQYVWDIYRRASETGTEINHSIAEDKIAGVDITDVDAVIDLSVKLCGTISSEISDYFKDDEVYAEYISSYLDFEYDGGNYKDSLNRFCNSDAVNDQKVALYYDGEHPKLNRNIILSKLYGERRFLEKITDRVSRSDIVEYYKLKKETSQYQGIFDSEDEQKNIKKFQEMKNIVEFRDLMDYSEIADELQGQLINWIYLRERDLMNFQLGYHYACLNNDSNKQATYVTLDYQGKKNRKINGAILYQICAMYINGLPLYYVDKDSSEWTVSDGKESTGAKIGEFYRYAKSFTSDCYASGLEIFENISEHDNITELRNYIEHFRYYSSFDRSFLGIYSEVFDRFFTYDLKYRKNVPTILYNILLQHFVNVRFEFVSGKKMIGIDKKIAKEKECARITIREKNGVYSEQFTYKLKNGTVYVDARDKRYLQSIIRLLFYPEKVNMDEMIEV 5w2h A 1.90 BS01 ADP A 1 I65 V73 K75 P111 E131 D132 V133 D144 L254 D275 I1 V9 K11 P47 E67 D68 V69 D80 L190 D206 2.7.1.151 Q8NFU5 ILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELRKYLPKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQKQLNFYASSLLFVYEGSGGEVEVRMIDFAHVFPSNTIDEGYVYGLKHLISVLRSILDN 5w2h A 1.90 BS02 I3P A 1 R82 K146 K160 Q163 Q164 K167 Q196 A250 H278 R18 K82 K96 Q99 Q100 K103 Q132 A186 H209 2.7.1.151 Q8NFU5 ILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELRKYLPKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQKQLNFYASSLLFVYEGSGGEVEVRMIDFAHVFPSNTIDEGYVYGLKHLISVLRSILDN 5w5n B 1.85 BS02 FUC B 1 Q295 F296 N297 Q62 F63 N64 P01861 EAAASSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLS 5wbm A 2.16 BS01 A4G A 1 A226 G229 A230 A244 P246 A256 F260 C282 A285 C289 A224 G227 A228 A242 P244 A254 F258 C280 A283 C287 2.7.1.3 P50053 28853885 GSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbm B 2.16 BS01 A4G B 1 R77 W88 R81 W92 2.7.1.3 P50053 28853885 SGLVPRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbm B 2.16 BS02 A4G B 2 A226 G229 A244 A256 F260 C282 A285 G286 C289 A230 G233 A248 A260 F264 C286 A289 G290 C293 2.7.1.3 P50053 28853885 SGLVPRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbo A 2.25 BS01 A1Y A 1 A224 A226 P246 A256 F260 C282 A285 G286 A222 A224 P244 A254 F258 C280 A283 G284 2.7.1.3 P50053 28853885 GSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbo B 2.25 BS01 A1Y B 1 A224 A226 E227 T253 A256 F260 C282 A285 C289 A227 A229 E230 T256 A259 F263 C285 A288 C292 2.7.1.3 P50053 28853885 GLVPRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbp A 2.74 BS01 A2J A 1 A226 E227 P246 P247 F260 A285 C289 A224 E225 P244 P245 F258 A283 C287 2.7.1.3 P50053 28853885 GSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbq A 2.40 BS01 A3J A 1 A224 A226 P246 P247 V250 T253 A256 G257 F260 A285 G286 C289 A222 A224 P244 P245 V248 T251 A254 G255 F258 A283 G284 C287 2.7.1.3 P50053 28853885 GSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbq B 2.40 BS01 A3J B 1 A224 A226 E227 P246 P247 A256 G257 F260 C289 A227 A229 E230 P249 P250 A259 G260 F263 C292 2.7.1.3 P50053 28853885 GLVPRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbr A 2.58 BS01 A3Y A 1 N107 A224 A226 E227 V250 T253 A256 G257 F260 C289 N105 A222 A224 E225 V248 T251 A254 G255 F258 C287 2.7.1.3 P50053 28853885 GSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbr B 2.58 BS01 A3Y B 1 A224 A226 E227 P246 P247 V250 T253 A256 G257 F260 C282 A285 G286 C289 A227 A229 E230 P249 P250 V253 T256 A259 G260 F263 C285 A288 G289 C292 2.7.1.3 P50053 28853885 GLVPRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbz A 2.40 BS01 A4J A 1 N107 A224 A226 E227 P246 P247 T253 A256 G257 F260 A285 G286 C289 N105 A222 A224 E225 P244 P245 T251 A254 G255 F258 A283 G284 C287 2.7.1.3 P50053 28853885 GSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5wbz B 2.40 BS01 A4J B 1 A224 A226 E227 P247 T253 A256 G257 F260 G286 C289 A227 A229 E230 P250 T256 A259 G260 F263 G289 C292 2.7.1.3 P50053 28853885 GLVPRGSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 5weh A 3.45 BS01 HEA A 1 L34 G37 G38 V45 T48 M51 R52 W95 I99 H102 G103 M106 M107 V110 V111 A114 G171 W172 Y414 F420 H421 M424 S425 V429 M460 T467 F468 Q471 R481 R482 A501 S504 F508 F511 L21 G24 G25 V32 T35 M38 R39 W82 I86 H89 G90 M93 M94 V97 V98 A101 G158 W159 Y401 F407 H408 M411 S412 V416 M447 T454 F455 Q458 R468 R469 A488 S491 F495 F498 1.9.3.1 P33517 28842531 RGFFTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTFEQLPKREDW 5weh A 3.45 BS02 HEA A 2 W172 W280 V287 V291 H333 T352 A356 T359 G360 I363 F364 F391 T392 G395 V396 G398 I399 L401 S402 D407 H411 V416 H419 F420 V423 M424 R481 W159 W267 V274 V278 H320 T339 A343 T346 G347 I350 F351 F378 T379 G382 V383 G385 I386 L388 S389 D394 H398 V403 H406 F407 V410 M411 R468 1.9.3.1 P33517 28842531 RGFFTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTFEQLPKREDW 5weh G 3.45 BS01 HEA G 1 L34 G38 V45 T48 M51 R52 I99 H102 G103 M106 M107 V110 V111 G171 W172 Y414 F420 H421 M424 S425 V429 I432 I436 M460 F468 Q471 R481 R482 A501 S504 F508 F511 L21 G25 V32 T35 M38 R39 I86 H89 G90 M93 M94 V97 V98 G158 W159 Y401 F407 H408 M411 S412 V416 I419 I423 M447 F455 Q458 R468 R469 A488 S491 F495 F498 1.9.3.1 P33517 28842531 RGFFTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTFEQLPKREDW 5weh G 3.45 BS02 HEA G 2 W172 W280 V287 V291 H333 H334 T352 I355 A356 T359 G360 I363 F364 F391 T392 G395 G398 I399 L401 S402 D407 H411 V416 H419 F420 V423 M424 R481 W159 W267 V274 V278 H320 H321 T339 I342 A343 T346 G347 I350 F351 F378 T379 G382 G385 I386 L388 S389 D394 H398 V403 H406 F407 V410 M411 R468 1.9.3.1 P33517 28842531 RGFFTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTFEQLPKREDW 5weh G 3.45 BS05 CA G 1 E54 A57 P58 G59 Q61 D485 E41 A44 P45 G46 Q48 D472 1.9.3.1 P33517 28842531 RGFFTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSESGYSTDLAIFAVHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEAFATWNFVSSLGAFLSFASFLFFLGVIFYTLTRGARVTANNYWNEHADTLEWTLTSPPPEHTFEQLPKREDW 5weh H 3.45 BS02 MG G 1 D229 E254 D200 E225 1.9.3.1 Q03736 28842531 LEIIGRPQPGGTGFQPSASPVATQIHWLDGFILVIIAAITIFVTLLILYAVWRFHEKRNKVPARFTHNSPLEIAWTIVPIVILVAIGAFSLPVLFNQQEIPEADVTVKVTGYQWYWGYEYPDEEISFESYMIGSPATGGDNRMSPEVEQQLIEAGYSRDEFLLATDTAMVVPVNKTVVVQVTGADVIHSWTVPAFGVKQDAVPGRLAQLWFRAEREGIFFGQCSELCGISHAYMPITVKVVSEEAYAAWLEQH 5wlh A 1.80 BS01 NUC B 1 K14 L15 T16 T21 A22 V23 R127 K129 R189 R231 Q235 V236 R238 S239 I240 N242 M243 N244 M245 S260 T264 S266 G267 R270 K274 W325 R332 R369 I373 Y376 R377 H403 R404 E406 Y407 E410 K411 N415 K417 F422 K423 K432 K435 Y440 I443 K444 K450 S483 Y486 E487 K490 M494 K639 S642 N643 R668 Q671 V672 P673 S674 N676 K677 V680 N683 L711 N715 Y719 K722 Y726 C820 M821 Q822 K823 K840 M841 A913 N916 Q927 Y928 D931 V968 G972 T973 R1036 Q1076 I1090 F1093 Q1094 K1097 N1098 R1103 R1128 E1228 E1231 N1232 I1233 F1267 D1268 K1276 Y1277 R1278 K1279 N1280 P1282 T1283 I1284 N1287 F1293 F1300 S1302 K1305 K1320 E1321 C1322 A1323 F1338 T1339 Y1340 K1341 R1352 K1 L2 T3 T8 A9 V10 R108 K110 R170 R212 Q216 V217 R219 S220 I221 N223 M224 N225 M226 S241 T245 S247 G248 R251 K255 W306 R313 R345 I349 Y352 R353 H379 R380 E382 Y383 E386 K387 N391 K393 F398 K399 K408 K411 Y416 I419 K420 K426 S459 Y462 E463 K466 M470 K613 S616 N617 R642 Q645 V646 P647 S648 N650 K651 V654 N657 L683 N687 Y691 K694 Y698 C746 M747 Q748 K749 K754 M755 A827 N830 Q841 Y842 D845 V882 G886 T887 R950 Q990 I1004 F1007 Q1008 K1011 N1012 R1017 R1042 E1142 E1145 N1146 I1147 F1181 D1182 K1190 Y1191 R1192 K1193 N1194 P1196 T1197 I1198 N1201 F1207 F1214 S1216 K1219 K1231 E1232 C1233 A1234 F1249 T1250 Y1251 K1252 R1263 KLTVNAKTAVVSENRSQEGILYNDPSRYGKSRKNDEDRDRYIESRLKSSGKLYRIFNETDELQWFLSEIVKKINRRNGLVLSDMLSVDDRAFEKAFEKYAELSYTNRRNKVSGSPAFETCGVDAATAERLKGIISETNFINRIKNNIDNKVSEDIIDRIIAKYLKKSLCRERVKRGLKKLLMNAFDLPYSDPDIDVQRDFIDYVLEDFYHVRAKSQVSRSIKNMNMPVQPEGDGKFAITVSKGGTESGNKRSAEKEAFKKFLSDYASLDERVRDDMLRRMRRLVVLYFYGSDDSKLSDVNEKFDVWEDAAARRVDNREFIKLPLENKTDKDAERIRKNTVKELYRNQNIGCYRQAVKAVEEDNNGRYFDDKMLNMFFIHRIEYGVEKIYANLKQVTEFKARTGYLSEKIWKDLINYISIKYIAMGKAVYNYAMDELNASDKKEIELGKISEEYLSGISSFDYELIKAEEMLQRETAVYVAFAARHLSSQTVELDSENSDFLLLKPKGTMDKNDKNKLASNNILNFLKDKETLRDTILQYFGGHSLWTDFPFDKYLAGGKDDVDFLTDLKDVIYSMRNDSFHYATHNNGKWNKELISAMFEHETERMTVVMKDKFYSNNLPMFYKNDDLKKLLIDLYKDNVERASQVPSFNKVFVRKNFPALVRDKDNLGIELDLDADKGENELKFYNALYYMFKEIYYNAFLNDKNVRERFITKAAENDFGQRIKNIVQVNPDYTLAQICQLIMTCMQKKSAYKMLLLVNLRKAFLEFIKENYAFVLKPYKHDLCDKADFVPDFAKYVKPYAGLISRVAGSSELQKWYIVSRFLSPAQANHMLGFLHSYKQYVWDIYRRASETGTEINHSIAEDKIAGVDITDVDAVIDLSVKLCGTISSEISDYFKDDEVYAEYISSYLDFEYDGGNYKDSLNRFCNSDAVNDQKVALYYDGEHPKLNRNIILSKLYGERRFLEKITDRVSRSDIVEYYKLKKETSQYQTKGIFDSEDEQKNIKKFQEMKNIVEFRDLMDYSEIADELQGQLINWIYLRERDLMNFQLGYHYACLNNDSNKQATYVTLDYQGKKNRKINGAILYQICAMYINGLPLYYVDKDSSEWTVSDGKESTGAKIGEFYRYAKSFENTSDCYASGLEIFENISEHDNITELRNYIEHFRYYSSFDRSFLGIYSEVFDRFFTYDLKYRKNVPTILYNILLQHFVNVRFEFVSGKKMIGIDKKIAKEKECARITIREKNGVYSEQFTYKLKNGTVYVDARDKRYLQSIIRLLFYPEKVNMDEMIEV 5wnx A 2.55 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 R258 Y271 R283 L287 T292 I293 N294 E295 Y296 H25 S220 K221 G222 E223 T224 K225 R249 Y262 R274 L278 T283 I284 N285 E286 Y287 2.7.7.7,4.2.99.- P06746 28862449 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5wo6 A 3.31 BS01 DTB A 1 L88 Y115 V151 L61 Y88 V124 Q9R186 SWAQSRDEQNLLQQKRIWESPLLLAAKENNVQALYKLLKFEGCEVHQKGAMGETALHIAALYDNNEAAQVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRQTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWQMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQD 5wo9 A 3.70 BS01 DTB A 1 R33 Q40 L88 Y115 V151 N158 R5 Q12 L60 Y87 V123 N130 Q9R186 WAQSRDEQNLLQQKRIWESPLLLAAKENNVQALYKLLKFEGCEVHQKGAMGETALHIAALYDNNEAAQVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDLGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQD 5wri A 1.60 BS01 III D 1 P78 E100 R102 R106 P161 F162 K165 V198 T199 I200 A201 F203 A218 R285 P14 E36 R38 R42 P97 F98 K101 V134 T135 I136 A137 F139 A154 R221 2.8.2.20 O60507 28821720 YHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKP 5wri A 1.60 BS02 III E 1 W114 S117 E120 R123 W50 S53 E56 R59 2.8.2.20 O60507 28821720 YHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKP 5wri A 1.60 BS03 A3P A 1 R79 S80 G81 T82 T83 L84 R184 S192 R196 Y239 S286 Q289 V290 K292 P293 V294 N295 K301 R15 S16 G17 T18 T19 L20 R120 S128 R132 Y175 S222 Q225 V226 K228 P229 V230 N231 K237 2.8.2.20 O60507 28821720 YHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKP 5wri B 1.60 BS01 III D 1 M113 W114 S117 E120 R123 M50 W51 S54 E57 R60 2.8.2.20 O60507 28821720 AYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYG 5wri B 1.60 BS05 ZN B 1 H267 E269 E270 H204 E206 E207 2.8.2.20 O60507 28821720 AYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYG 5x3d A 1.93 BS01 7XL A 1 G9 M10 S11 A12 H16 G18 H19 I22 Y45 K46 Y77 H91 G92 D94 Q100 Y123 T124 I127 G8 M9 S10 A11 H15 G17 H18 I21 Y44 K45 Y76 H90 G91 D93 Q99 Y122 T123 I126 P96074 28727444 QRPIVYVGMSADLIHPGHINILSRAAELGDITIGLLTDAAIASYKRLPHMTYEQRKAVVENLKGVASVVPQRTLDYAENLRTVRPDFVVHGDDWQTGVQRHTRERVIEVLSEWGGKLVEIPYTPGI 5x79 A 1.90 BS01 GF5 A 1 Y8 F9 V11 R14 W39 K45 Q52 L53 P54 Q65 S66 Y109 N205 G206 Y8 F9 V11 R14 W39 K45 Q52 L53 P54 Q65 S66 Y109 N205 G206 2.5.1.18 P09211 28848941 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ 5x7b A 2.45 BS01 III L 1 E17 R32 S34 K35 S36 T42 T52 H53 K89 E15 R30 S32 K33 S34 T40 T50 H51 K87 3.1.3.48 Q06124 SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR 5x7b A 2.45 BS02 III N 1 R138 S140 Q141 S142 V148 T168 H169 V170 M171 M202 E204 T205 R136 S138 Q139 S140 V146 T154 H155 V156 M157 M188 E190 T191 3.1.3.48 Q06124 SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR 5x94 A 2.60 BS01 III L 1 E17 R32 S34 K35 S36 T42 T52 H53 I54 K55 L65 G67 G68 Y81 L88 K89 E90 E14 R29 S31 K32 S33 T39 T49 H50 I51 K52 L62 G64 G65 Y78 L85 K86 E87 3.1.3.48 Q06124 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTT 5x94 A 2.60 BS02 III N 1 G119 K120 R138 S140 Q141 S142 V148 T168 H169 V181 G182 G183 M202 V203 E204 T205 L210 G116 K117 R135 S137 Q138 S139 V145 T155 H156 V168 G169 G170 M189 V190 E191 T192 L197 3.1.3.48 Q06124 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTT 5x94 B 2.60 BS01 III M 1 R32 S34 K35 S36 T42 T52 H53 K55 G67 L88 K89 E90 R30 S32 K33 S34 T40 T50 H51 K53 G65 L86 K87 E88 3.1.3.48 Q06124 SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR 5x94 B 2.60 BS02 III O 1 R138 S140 Q141 S142 V148 T168 H169 M171 V181 G182 G183 G184 M202 V203 E204 T205 R136 S138 Q139 S140 V146 T155 H156 M158 V168 G169 G170 G171 M189 V190 E191 T192 3.1.3.48 Q06124 SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR 5xfn A 1.90 BS01 ZN A 1 C107 C110 C136 C139 C82 C85 C105 C108 O43189 GPRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSRLLSALNSHKDRFISGCLFGLHARMPPPV 5xfn A 1.90 BS02 ZN A 2 C90 C93 H115 C118 C65 C68 H90 C93 O43189 GPRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSRLLSALNSHKDRFISGCLFGLHARMPPPV 5xfp B 2.30 BS01 NUC C 1 K323 K324 R325 K326 K288 K289 R290 K291 O43189 RLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSRLLSALNSHKDRFISGREIKKRKCLFGLHARMPPPVE 5xfp B 2.30 BS02 NUC D 1 K268 K269 Y270 I322 K323 K324 K233 K234 Y235 I287 K288 K289 O43189 RLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSRLLSALNSHKDRFISGREIKKRKCLFGLHARMPPPVE 5xfq A 2.40 BS02 NUC D 1 R320 K323 K324 R293 K296 K297 Q9Z1B8 RPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPGEGEGASWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSQLLSALNSHKDRFISGREIKKRKCLFGLHARTPPPV 5xfq A 2.40 BS03 III E 1 L38 W41 L45 L46 Y47 F65 E66 D67 F71 C110 C139 A142 T145 R147 L11 W14 L18 L19 Y20 F38 E39 D40 F44 C83 C112 A115 T118 R120 Q9Z1B8 RPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPGEGEGASWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSQLLSALNSHKDRFISGREIKKRKCLFGLHARTPPPV 5xfq A 2.40 BS04 III F 1 E59 Y169 G170 E32 Y142 G143 Q9Z1B8 RPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPGEGEGASWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSQLLSALNSHKDRFISGREIKKRKCLFGLHARTPPPV 5xfq B 2.40 BS01 III F 1 L38 W41 L45 L46 Y47 F65 E66 D67 C139 A142 I143 L9 W12 L16 L17 Y18 F36 E37 D38 C99 A102 I103 Q9Z1B8 RLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSQLLSALNSHKDRFISGREIKKRKCLFGLHARTPPPVE 5xfr A 2.25 BS01 III C 1 W56 L60 F61 Y62 F80 D82 S84 R162 W13 L17 F18 Y19 F37 D39 S41 R114 Q9Y483 CKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGAMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDCSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNV 5xfr A 2.25 BS02 ZN A 1 C105 C108 H130 C133 C57 C60 H82 C85 Q9Y483 CKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGAMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDCSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNV 5xfr A 2.25 BS03 ZN A 2 C122 C125 C151 C154 C74 C77 C103 C106 Q9Y483 CKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGAMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDCSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNV 5xfr B 2.25 BS02 NUC E 1 K282 K284 Y285 I337 K338 K339 K222 K224 Y225 I277 K278 K279 Q9Y483 KFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDCKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVA 5xfr B 2.25 BS03 NUC F 1 K338 K339 K340 K341 K278 K279 K280 K281 Q9Y483 KFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDCKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVA 5xja A 3.43 BS01 ADP A 1 R260 R262 P263 Q345 T346 G347 S348 G349 K350 T351 H352 L358 R37 R39 P40 Q122 T123 G124 S125 G126 K127 T128 H129 L135 Q922S8 PNWEFARMIKEFRVTMECSPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLQNASKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLEDSRQQVQVVGLQEYLVTCADDVIKMINMGSACRTSSRSHACFQILLRTKGRLHGKFSLVDLAGNERGARQTRMEGAEINKSLLALKECIRALGQFRESKLTQVLRDSFIGENSRTCMIAMISPGISSCEYTLNTLRYADRVKELS 5xja A 3.43 BS02 AF3 A 1 T351 R452 S463 S464 D488 T128 R225 S227 S228 D252 Q922S8 PNWEFARMIKEFRVTMECSPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLQNASKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLEDSRQQVQVVGLQEYLVTCADDVIKMINMGSACRTSSRSHACFQILLRTKGRLHGKFSLVDLAGNERGARQTRMEGAEINKSLLALKECIRALGQFRESKLTQVLRDSFIGENSRTCMIAMISPGISSCEYTLNTLRYADRVKELS 5xja B 3.43 BS01 ADP B 1 R260 P263 T346 G347 S348 G349 K350 T351 H352 L358 R37 P40 T123 G124 S125 G126 K127 T128 H129 L135 Q922S8 PNWEFARMIKEFRVTMECSPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLQNASKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLEDSRQQVQVVGLQEYLVTCADDVIKMINMGSACRTSSRSHACFQILLRTKGRLHGKFSLVDLAGNERRMEGAEINKSLLALKECIRALGQFRESKLTQVLRDSFIGENSRTCMIAMISPGISSCEYTLNTLRYADRVKELS 5xja B 3.43 BS02 AF3 B 1 T351 S463 S464 D488 L489 T128 S227 S228 D252 L253 Q922S8 PNWEFARMIKEFRVTMECSPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLQNASKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLEDSRQQVQVVGLQEYLVTCADDVIKMINMGSACRTSSRSHACFQILLRTKGRLHGKFSLVDLAGNERRMEGAEINKSLLALKECIRALGQFRESKLTQVLRDSFIGENSRTCMIAMISPGISSCEYTLNTLRYADRVKELS 5xjb A 3.10 BS01 ADP A 1 R260 R262 P263 T346 G347 S348 G349 K350 T351 H352 R37 R39 P40 T123 G124 S125 G126 K127 T128 H129 Q922S8 PNWEFARMIKEFRVTMECSPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGQNASKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLEDSRQQVQVVGLQEYLVTCADDVIKMINMGSACRTSGQSSRSHACFQILLRTKGRLHGKFSLVDLAGNERGADRMEGAEINKSLLALKECIRALGQNKHTPFRESKLTQVLRDSFIGENSRTCMIAMISPGISSCEYTLNTLRYADRVKELS 5xjb A 3.10 BS02 BEF A 1 K350 R452 S463 S464 S466 D488 L489 A490 K127 R223 S228 S229 S231 D253 L254 A255 Q922S8 PNWEFARMIKEFRVTMECSPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGQNASKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLEDSRQQVQVVGLQEYLVTCADDVIKMINMGSACRTSGQSSRSHACFQILLRTKGRLHGKFSLVDLAGNERGADRMEGAEINKSLLALKECIRALGQNKHTPFRESKLTQVLRDSFIGENSRTCMIAMISPGISSCEYTLNTLRYADRVKELS 5xjb A 3.10 BS03 MG A 1 T351 S463 T128 S228 Q922S8 PNWEFARMIKEFRVTMECSPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGQNASKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLEDSRQQVQVVGLQEYLVTCADDVIKMINMGSACRTSGQSSRSHACFQILLRTKGRLHGKFSLVDLAGNERGADRMEGAEINKSLLALKECIRALGQNKHTPFRESKLTQVLRDSFIGENSRTCMIAMISPGISSCEYTLNTLRYADRVKELS 5xjb B 3.10 BS02 BEF B 1 K350 R452 S463 S464 S466 D488 L489 K127 R224 S225 S226 S228 D250 L251 Q922S8 PNWEFARMIKEFRVTMECSPLTVTDPIEEHRICVCVRKRPLNKQELAKKEIDVISVPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDQNASKGIYAMASRDVFLLKNQPRYRNLNLEVYVTFFEIYNGKVFDLLNKKAKLRVLEDSRQQVQVVGLQEYLVTCADDVIKMINMGSACRSSRSHACFQILLRTKGRLHGKFSLVDLAGNERGARMEGAEINKSLLALKECIRALGQPFRESKLTQVLRDSFIGENSRTCMIAMISPGISSCEYTLNTLRYADRVKELS 5xpd A 2.79 BS01 DCM A 1 S20 L23 F24 I75 W180 P195 N196 S15 L18 F19 I70 W175 P190 N191 NLWAFVFGILGNIISFVLFLAPVPTFVRICKKKSTEGFQSLPYVSALFNAMLWIYYAMQKDGTAFLLITINAFGCVIETIYIVLFVSYANKKTRISTLKVLGLLNFLGFAAIVLVCELLTKGSTREKVLGGICVGFSVSMFAAPLSIMRVVVRTRSVEFMPFSLSLFLTINAVTWLFYGLAIKDFYVALPNVLGAFLGAVQMILYIIFKYYKTPVAQMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGVGKDQFEEV 5xs3 A 2.50 BS01 III C 1 Y7 D9 S24 Y59 R62 E63 K66 Y67 R69 Q70 N77 K80 L81 Y84 W97 Y99 Y123 T143 K146 W147 E152 Q155 W156 Y159 W167 Y171 Y6 D8 S21 Y56 R59 E60 K63 Y64 R66 Q67 N74 K77 L78 Y81 W94 Y96 Y120 T140 K143 W144 E149 Q152 W153 Y156 W164 Y168 28655516 SHSMRYFDTAVSRPGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVNLRKLRGYYNQSEDGSHTLQWMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQWRAYLEGTCVEWLRRYLENGKETLQRAEHPKTHVTHHPVSDHEATLRCWALGFYPARITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRW 5xtn A 2.54 BS01 FAD A 1 R10 F106 T107 I109 W110 M113 H114 F151 M157 A158 H161 Y162 M222 H225 N226 I228 N229 K232 Q235 M247 Y252 R10 F98 T99 I101 W102 M105 H106 F141 M147 A148 H151 Y152 M209 H212 N213 I215 N216 K219 Q222 M229 Y234 1.8.3.2 P41480 MIPLTPLFSRYKDSYLLYSFRLIDLLRASKSTHLTKLLSSQATYLYHFIQKYEVQQLIEWAINASPDMDLQQFRIEFMDKTTELNLRSCQPKSFTYTFTTIWDTMHFLSLIIDDMVYTRDKLDFVMQQLKTMKVLFYNVFFILQAAMARDHYMNVKGFIIYHIELIEIALDKEKYGTDITFVDSYQQETAGADVSNNMLMKNLMAYVSMTFHNHINDYKWIQRNKKPRMTWGEYKKLLNL 5xto D 2.56 BS01 FAD D 1 R10 F106 T107 I109 W110 M113 V149 F150 M157 C158 H161 Y162 M222 H225 N226 I228 N229 K232 Q235 R236 M247 Y252 R13 F105 T106 I108 W109 M112 V148 F149 M156 C157 H160 Y161 M218 H221 N222 I224 N225 K228 Q231 R232 M239 Y244 1.8.3.2 P41480 RGSMIPLTPLFSRYKDSYLLYSFRLIDLLRASKSTHLTKLLSSQATYLYHFACKDIQKYEVQQLIEWAINASPDMDLQQFRIEFMDKTTELNLRSCQPKSFTYTFTTIWDTMAFLSLIIDDMVYTRDKSSLDFVMQQLKTMKVLFYNVFFILQCAMCRDHYMNVKGFIIYHIELIEIALDKEKYGTDITFVDSYQQETAGADVSNNMLMKNLMAYVSMTFHNHINDYKWIQRNKKPERMTWGEYKKLLNLQ 5xtp C 2.40 BS01 FAD C 1 F106 T107 I109 W110 M113 H114 V149 F150 C158 H161 Y162 M222 H225 N226 I228 N229 K232 Q235 R236 M247 Y252 F103 T104 I106 W107 M110 H111 V146 F147 C155 H158 Y159 M215 H218 N219 I221 N222 K225 Q228 R229 M238 Y243 1.8.3.2 P41480 SMIPLTPLFSRYKDSYLLYSFRLIDLLRASKSTHLTKLLSSQATYLYHFACKDIQKYEVQQLIEWAINASPDMDLQQFRIEFMDKTTELNLRSCQPKSFTYTFTTIWDTMHFLSLIIDDMVYTRDKSSLDFVMQQLKTMKVLFYNVFFILQCAMCRDHYMNVKGFIIYHIELIEIALDKEKYGTDITFVDSYQQETAGADVNNMLMKNLMAYVSMTFHNAINDYKWIQRNKKPPAERMTWGEYKKLLNL 5xwp A 3.09 BS01 NUC C 1 S0 M1 K2 V3 T4 K5 S10 H11 K13 N139 K140 S143 L144 Y146 S147 F148 K150 N151 R172 Y176 R224 H228 R233 K237 A241 Y245 Q271 Y274 K275 Y276 H294 E297 I298 S301 K305 Y307 Y309 R311 K319 R322 K336 N339 K340 S363 I366 A367 R370 Q371 A374 F375 R377 N378 I380 G381 V546 N547 K548 N549 V553 S555 K558 Y601 K718 Q719 D722 K723 H771 T775 S780 K783 Y784 S786 A787 N804 L805 N808 R809 K845 D849 N852 R857 I897 E898 H901 Y938 K942 H962 R963 G966 Y967 R973 R1079 K1080 N1083 A1084 M1086 K1087 S1088 F1102 I1104 G1105 A1106 S1 M2 K3 V4 T5 K6 S11 H12 K14 N135 K136 S139 L140 Y142 S143 F144 K146 N147 R168 Y172 R220 H224 R229 K233 A237 Y241 Q267 Y270 K271 Y272 H290 E293 I294 S297 K301 Y303 Y305 R307 K311 R314 K328 N331 K332 S355 I358 A359 R362 Q363 A366 F367 R369 N370 I372 G373 V538 N539 K540 N541 V545 S547 K550 Y593 K690 Q691 D694 K695 H743 T747 S752 K755 Y756 S758 A759 N776 L777 N780 R781 K817 D821 N824 R829 I869 E870 H873 Y910 K914 H934 R935 G938 Y939 R945 R1051 K1052 N1055 A1056 M1058 K1059 S1060 F1074 I1076 G1077 A1078 C7NBY4 28757251 SMKVTKVGGISHKKYTSEGRLVKSESEENRTDERLSALLNMRLDMYIKNPSSTETKENQKRIGKLKKFFSNKMVYLKDNTLSLKNGKKENIDREYSETDVRDKKNFAVLKKIYLNENVNSEELEVFRNDIKKKLNKINSLKYSFEKNKANYQKINENNIEKVEGKSKRNIIYDYYRESAKRDAYVSNVKEAFDKLYKEEDIAKLVLEIENLTKLEKYKIREFYHEIIGRKNDKENFAKIIYEEIQNVNNMKELIEKVPDMSELKKSQVFYKYYLDKEELNDKNIKYAFCHFVEIEMSQLLKNYVYKRSNDKIKRIFEYQNLKKLIENKLLNKLDTYVRNCGKYNYYLQDGEIATSDFIARNRQNEAFLRNIIGVSSVAYFSLRNILETENENDITGRMRGKTVKNNKGEEKYVSGEVDKIYNENKKNEVKENLKMFYSYDFNMDNKNEIEDFFANIDEAISSIRHGIVHFNLELEGKDIFAFKNIAPSEISKKMFQNEINEKKLKLKIFRQLNSANVFRYLEKYKILNYLKRTRFEFVNKNIPFVPSFTKLYSRIDDLKNSLGIYWKTPKTNDDNKTKEIIDAQIYLLKNIYYGEFLNYFMSNNGNFFEISKEIIELNKNDFEDIQEKIPKEYLANIQSLYMINAGDTYIDFIQKIFLKGFMTYLANNGRLSLIYIGSDEETNTSLAEKKQEFDKFLKKYEQNNNIKIPYEINEFLREIKLGNILKYTERLNMFYLILKLLNHKELTNLKGSLEKYQSANKEEAFSDQLELINLLNLDNNRVTEDFELEADEIGKFLDFNGNKVKDNKELKKFDTNKIYFDGENIIKHRAFYNIKKYGMLNLLEKIADKAGYKISIEELKKYSNKKNEIEKNHKMQENLHRKYARPRKDEKFTDEDYESYKQAIENIEEYTHLKNKVEFNELNLLQGLLLRILHRLVGYTSIWERDLRFRLKGEFPENQYIEEIFNFENKKNVKYKGGQIVEKYIKFYKELHQNDEVKINKYSSANIKVLKQEKKDLYIANYIAAFNYIPHAEISLLEVLENLRKLLSYDRKLKNAVMKSVVDILKEYGFVATFKIGADKKIGIQTLESEKIVHLKNLKKKKLMTDRNSEELCKLVKIMFEYKME 5xwp A 3.09 BS02 NUC D 1 S0 R41 M44 K47 K86 R518 Q519 S522 N549 P551 T557 D590 K597 A656 Q659 S660 M663 K772 T775 G779 E782 K783 S786 R809 V810 I854 K855 H856 R857 K894 Q904 H908 E1095 I1120 R1135 S1 R42 M45 K48 K87 R510 Q511 S514 N541 P543 T549 D582 K589 A635 Q638 S639 M642 K744 T747 G751 E754 K755 S758 R781 V782 I826 K827 H828 R829 K866 Q876 H880 E1067 I1092 R1107 C7NBY4 28757251 SMKVTKVGGISHKKYTSEGRLVKSESEENRTDERLSALLNMRLDMYIKNPSSTETKENQKRIGKLKKFFSNKMVYLKDNTLSLKNGKKENIDREYSETDVRDKKNFAVLKKIYLNENVNSEELEVFRNDIKKKLNKINSLKYSFEKNKANYQKINENNIEKVEGKSKRNIIYDYYRESAKRDAYVSNVKEAFDKLYKEEDIAKLVLEIENLTKLEKYKIREFYHEIIGRKNDKENFAKIIYEEIQNVNNMKELIEKVPDMSELKKSQVFYKYYLDKEELNDKNIKYAFCHFVEIEMSQLLKNYVYKRSNDKIKRIFEYQNLKKLIENKLLNKLDTYVRNCGKYNYYLQDGEIATSDFIARNRQNEAFLRNIIGVSSVAYFSLRNILETENENDITGRMRGKTVKNNKGEEKYVSGEVDKIYNENKKNEVKENLKMFYSYDFNMDNKNEIEDFFANIDEAISSIRHGIVHFNLELEGKDIFAFKNIAPSEISKKMFQNEINEKKLKLKIFRQLNSANVFRYLEKYKILNYLKRTRFEFVNKNIPFVPSFTKLYSRIDDLKNSLGIYWKTPKTNDDNKTKEIIDAQIYLLKNIYYGEFLNYFMSNNGNFFEISKEIIELNKNDFEDIQEKIPKEYLANIQSLYMINAGDTYIDFIQKIFLKGFMTYLANNGRLSLIYIGSDEETNTSLAEKKQEFDKFLKKYEQNNNIKIPYEINEFLREIKLGNILKYTERLNMFYLILKLLNHKELTNLKGSLEKYQSANKEEAFSDQLELINLLNLDNNRVTEDFELEADEIGKFLDFNGNKVKDNKELKKFDTNKIYFDGENIIKHRAFYNIKKYGMLNLLEKIADKAGYKISIEELKKYSNKKNEIEKNHKMQENLHRKYARPRKDEKFTDEDYESYKQAIENIEEYTHLKNKVEFNELNLLQGLLLRILHRLVGYTSIWERDLRFRLKGEFPENQYIEEIFNFENKKNVKYKGGQIVEKYIKFYKELHQNDEVKINKYSSANIKVLKQEKKDLYIANYIAAFNYIPHAEISLLEVLENLRKLLSYDRKLKNAVMKSVVDILKEYGFVATFKIGADKKIGIQTLESEKIVHLKNLKKKKLMTDRNSEELCKLVKIMFEYKME 5xwp B 3.09 BS01 NUC E 1 S0 M1 K2 V3 T4 K5 S10 H11 K13 N139 K140 S143 L144 Y146 S147 F148 K150 N151 K171 R172 Y176 R224 H228 R233 K237 A241 K242 Y245 K268 Q271 Y274 K275 Y276 H294 E297 S301 Q302 K305 Y307 Y309 N339 K340 S363 I366 A367 R370 Q371 A374 F375 R377 N378 I380 G381 V546 N547 K548 N549 V553 S555 N583 E587 Y601 K718 Q719 D722 H771 T775 K778 S780 K783 Y784 A787 N804 L805 N808 R809 K845 D849 G850 E851 I897 E898 H901 Y938 T939 K942 N943 H962 R963 G966 Y967 I970 R973 R1079 K1080 L1081 K1082 N1083 M1086 K1087 S1088 F1102 I1104 A1106 S1 M2 K3 V4 T5 K6 S11 H12 K14 N131 K132 S135 L136 Y138 S139 F140 K142 N143 K163 R164 Y168 R216 H220 R225 K229 A233 K234 Y237 K260 Q263 Y266 K267 Y268 H286 E289 S293 Q294 K297 Y299 Y301 N326 K327 S350 I353 A354 R357 Q358 A361 F362 R364 N365 I367 G368 V533 N534 K535 N536 V540 S542 N570 E574 Y588 K679 Q680 D683 H732 T736 K739 S741 K744 Y745 A748 N765 L766 N769 R770 K806 D810 G811 E812 I858 E859 H862 Y899 T900 K903 N904 H923 R924 G927 Y928 I931 R934 R1040 K1041 L1042 K1043 N1044 M1047 K1048 S1049 F1063 I1065 A1067 C7NBY4 28757251 SMKVTKVGGISHKKYTSEGRLVKSESEENRTDERLSALLNMRLDMYIKNPSSTETKENQKRIGKLKKFFSNKMVYLKDNTLSLKNGKKENIDRSDVRDKKNFAVLKKIYLNENVNSEELEVFRNDIKKKLNKINSLKYSFEKNKANYQKINENNIEKVEGKSKRNIIYDYYRESAKRDAYVSNVKEAFDKLYKEEDIAKLVLEIENLTKLEKYKIREFYHEIIGRKNDKENFAKIIYEEIQNVNNMKELIEKVPDMSELKKSQVFYKYYLDKEELNDKNIKYAFCHFVEIEMSQLLKNYVYKRNDKIKRIFEYQNLKKLIENKLLNKLDTYVRNCGKYNYYLQDGEIATSDFIARNRQNEAFLRNIIGVSSVAYFSLRNILETENENDITGRMRGKTVKNNKGEEKYVSGEVDKIYNENKKNEVKENLKMFYSYDFNMDNKNEIEDFFANIDEAISSIRHGIVHFNLELEGKDIFAFKNIAPSEISKKMFQNEINEKKLKLKIFRQLNSANVFRYLEKYKILNYLKRTRFEFVNKNIPFVPSFTKLYSRIDDLKNSLGIYWKTPKTNDDNKTKEIIDAQIYLLKNIYYGEFLNYFMSNNGNFFEISKEIIELNKNDKRNPKEYLANIQSLYMINADTYIDFIQKIFLKGFMTYLANNGRLSLIYIGSDEETNTSLAEKKQEFDKFLKKYEQNNNIKIPYEINEFLREIKLGNILKYTERLNMFYLILKLLNHKELTNLKGSLEKYQSANKEEAFSDQLELINLLNLDNNRVTEDFELEADEIGKFLDFNGNKVKDNKELKKFDTNKIYFDGENIIKHRAFYNIKKYGMLNLLEKIADKAGYKISIEELKKYSNKKNEIEKNHKMQENLHRKYARPRKDEKFTDEDYESYKQAIENIEEYTHLKNKVEFNELNLLQGLLLRILHRLVGYTSIWERDLRFRLKGEFPENQYIEEIFNFENKKNVKYKGGQIVEKYIKFYKELHQNDEVKINKYSSANIKVLKQEKKDLYIANYIAAFNYIPHAEISLLEVLENLRKLLSYDRKLKNAVMKSVVDILKEYGFVATFKIGADKKIGIQTLESEKIVHLKNLKKKKLMTDRNSEELCKLVKIMFEYKME 5xwp B 3.09 BS02 NUC F 1 R41 R518 Q519 S522 A523 F552 T557 K586 D590 I593 K597 S660 M663 K772 T775 G779 E782 K783 S786 R809 V810 I854 K855 H856 R857 Q904 H908 E1095 I1120 R1135 R42 R505 Q506 S509 A510 F539 T544 K573 D577 I580 K584 S629 M632 K733 T736 G740 E743 K744 S747 R770 V771 I815 K816 H817 R818 Q865 H869 E1056 I1081 R1096 C7NBY4 28757251 SMKVTKVGGISHKKYTSEGRLVKSESEENRTDERLSALLNMRLDMYIKNPSSTETKENQKRIGKLKKFFSNKMVYLKDNTLSLKNGKKENIDRSDVRDKKNFAVLKKIYLNENVNSEELEVFRNDIKKKLNKINSLKYSFEKNKANYQKINENNIEKVEGKSKRNIIYDYYRESAKRDAYVSNVKEAFDKLYKEEDIAKLVLEIENLTKLEKYKIREFYHEIIGRKNDKENFAKIIYEEIQNVNNMKELIEKVPDMSELKKSQVFYKYYLDKEELNDKNIKYAFCHFVEIEMSQLLKNYVYKRNDKIKRIFEYQNLKKLIENKLLNKLDTYVRNCGKYNYYLQDGEIATSDFIARNRQNEAFLRNIIGVSSVAYFSLRNILETENENDITGRMRGKTVKNNKGEEKYVSGEVDKIYNENKKNEVKENLKMFYSYDFNMDNKNEIEDFFANIDEAISSIRHGIVHFNLELEGKDIFAFKNIAPSEISKKMFQNEINEKKLKLKIFRQLNSANVFRYLEKYKILNYLKRTRFEFVNKNIPFVPSFTKLYSRIDDLKNSLGIYWKTPKTNDDNKTKEIIDAQIYLLKNIYYGEFLNYFMSNNGNFFEISKEIIELNKNDKRNPKEYLANIQSLYMINADTYIDFIQKIFLKGFMTYLANNGRLSLIYIGSDEETNTSLAEKKQEFDKFLKKYEQNNNIKIPYEINEFLREIKLGNILKYTERLNMFYLILKLLNHKELTNLKGSLEKYQSANKEEAFSDQLELINLLNLDNNRVTEDFELEADEIGKFLDFNGNKVKDNKELKKFDTNKIYFDGENIIKHRAFYNIKKYGMLNLLEKIADKAGYKISIEELKKYSNKKNEIEKNHKMQENLHRKYARPRKDEKFTDEDYESYKQAIENIEEYTHLKNKVEFNELNLLQGLLLRILHRLVGYTSIWERDLRFRLKGEFPENQYIEEIFNFENKKNVKYKGGQIVEKYIKFYKELHQNDEVKINKYSSANIKVLKQEKKDLYIANYIAAFNYIPHAEISLLEVLENLRKLLSYDRKLKNAVMKSVVDILKEYGFVATFKIGADKKIGIQTLESEKIVHLKNLKKKKLMTDRNSEELCKLVKIMFEYKME 5xwy A 3.20 BS01 NUC B 1 M1 V3 T4 K5 S10 H11 K12 K135 N139 K140 S143 L144 Y146 S147 F148 K150 N151 R172 Y176 R224 H228 R233 D236 K237 A241 Y245 K268 Q271 K275 Y276 E297 K305 Y307 Y309 I315 K319 R322 K336 N339 K340 S363 I366 A367 R370 Q371 R377 F552 S555 K558 D565 S569 K597 Y601 N626 R631 N632 F637 Y638 K639 Q659 S660 Y662 M663 I664 I678 K683 H771 T775 N776 K778 G779 K783 N804 N807 R809 H901 Q904 H908 A912 R963 Y967 R1072 R1079 K1080 L1081 K1082 N1083 M1086 K1087 S1088 E1095 F1102 I1104 A1106 K1108 I1120 V1121 H1122 L1123 K1124 N1125 K1127 M1 V3 T4 K5 S10 H11 K12 K99 N103 K104 S107 L108 Y110 S111 F112 K114 N115 R136 Y140 R188 H192 R197 D200 K201 A205 Y209 K232 Q235 K239 Y240 E261 K269 Y271 Y273 I279 K283 R286 K300 N303 K304 S327 I330 A331 R334 Q335 R341 F516 S519 K522 D529 S533 K561 Y565 N590 R595 N596 F601 Y602 K603 Q623 S624 Y626 M627 I628 I642 K647 H735 T739 N740 K742 G743 K747 N768 N771 R773 H865 Q868 H872 A876 R927 Y931 R1036 R1043 K1044 L1045 K1046 N1047 M1050 K1051 S1052 E1059 F1066 I1068 A1070 K1072 I1084 V1085 H1086 L1087 K1088 N1089 K1091 C7NBY4 28757251 MKVTKVGGISHKKYTSEGRLVKSESEENRTDERLSALLNMRLDMYINQKRIGKLKKFFSNKMVYLKDNTLSLKNGFAVLKKIYLNENSEELEVFRNDIKKKLNKINSLKYSFEKNKANYQKINENNIEKVEGKSKRNIIYDYYRESAKRDAYVSNVKEAFDKLYKEEDIAKLVLEIENLTKLEKYKIREFYHEIIGRKNDKENFAKIIYEEIQNVNNMKELIEKVPDMSELKKSQVFYKYYLDKEELNDKNIKYAFCHFVEIEMSQLLKNYVYKRLSNISNDKIKRIFEYQNLKKLIENKLLNKLDTYVRNCGKYNYYLQDGEIATSDFIARNRQNEAFLRNIIGVSSVAYFSLRNILETENENDITGRMRGKTVKNNKGEEKYVSGEVDKIYNENKKNEVKENLKMFYSYDFNMDNKNEIEDFFANIDEAISSIRHGIVHFNLELEGKDIFAFKNIAPSEISKKMFQNEINEKKLKLKIFRQLNSANVFRYLEKYKILNYLKRTRFEFVNKNIPFVPSFTKLYSRIDDLKNSLGIYWKTPKTNDDNKTKEIIDAQIYLLKNIYYGEFLNYFMSNNGNFFEISKEIIELNKNDKRNLKTGFYKLQKFEDIQEKIPKEYLANIQSLYMINAGNQDEEEKDTYIDFIQKIFLKGFMTYLANNGRLSLIYIGSDEETNTSLAEKKQEFDKFLKKYEQNNNIKIPYEINEFLREIKLGNILKYTERLNMFYLILKLLNHKELTNLKGSLEKYQSANKEEAFSDQLELINLLNLDNNRVTEDFELEADEIGKFLDFNGNKVKDNKELKKFDTNKIYFDGENIIKHRAFYNIKKYGMLNLLEKIADKAGYKISIEELKKYSNKKNEIEKNHKMQENLHRKYARPRKDEKFTDEDYESYKQAIENIEEYTHLKNKVEFNELNLLQGLLLRILHRLVGYTSIWERDLRFRLKGEFPENQYIEEIFNFENKKNVKYKGGQIVEKYIKFYKELHQNDEVKINKYSSANIKVLKQEKKDLYIANYIAAFNYIPHAEISLLEVLENLRKLLSYDRKLKNAVMKSVVDILKEYGFVATFKIGADKKIGIQTLESEKIVHLKNLKKKKLMTDRNSEELCKLVKIMFEYKME 5y1i A 2.00 BS01 HEM A 1 H75 F99 A100 H107 R111 F118 M244 A248 G249 T252 T253 M256 I296 A297 R303 L326 A355 F356 G357 H361 C363 L364 G365 A369 H57 F76 A77 H84 R88 F95 M218 A222 G223 T226 T227 M230 I270 A271 R277 L300 A329 F330 G331 H335 C337 L338 G339 A343 E0D207 28869713 APEWPMTGCPFDPPPGVRKLLAEKPLSRARIWDGSTPWVVTRHADQRALLSDPRVSHDGLRDGYPHISADFKFLSFAGQDDPEHGRIRRMVTLPFTARRIEAMRPAIQKITDELIDGMLAGPKPVDLVEALALPVPVRVICEMLGVPYEDREFLQQNNNAMIYRDTAQGDAQKAAIAQAMYLKELVGTKLGDDILSDLAVQVEAGEITQDDAAGIGMMLLGAGHETTANMIALGTLALLENPEQLAEVRDSDDPKVIVNTVEELLRYLTIAQDTVRRIAAEDIEIGGVVIKAGEGIVFPLNAANWDPDLYPEAPDRLDIHRANARRHLAFGYGVHQCLGATLARVELQIVYSTLLRRIPTLALAGTLDEIPFKHDQIAHGVYELPVTW 5y9a A 1.10 BS01 AR3 A 1 A18 Q19 W27 K152 Q158 D162 A21 Q22 W30 K155 Q161 D165 3.1.1.29 D0C9L6 GSHMSNISLIVGLGNPGSEYAQTRHNAGFWFVEQLADKYGITLKNDPKFHGISGRGNIEGHDVRLLLPMTYMNRSGQSVVPFSKFYQIAPEAILIAHDELDMNPGVIRLKTGGGHGGHNGLRDIVPHIGPNFHRLRIGIGHPGSKERVSGHVLGKAPSNEQSLMDGAIDHALSKVKLLVQGQVPQAMNQINAYKPA 6atf A 1.90 BS01 III C 1 Q9 E11 F24 I31 F32 A52 S53 F54 N62 V65 N69 I72 M73 R76 Q7 E9 F22 I29 F30 A50 S51 F52 N60 V63 N67 I70 M71 R74 P01903 28801345 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDT 6atf B 1.90 BS01 III C 1 E9 S11 T12 S13 E28 Y30 N37 D57 Y60 W61 R71 Y78 H81 N82 V85 G86 F89 E8 S10 T11 S12 E27 Y29 N36 D56 Y59 W60 R70 Y77 H80 N81 V84 G85 F88 A0A0A1I7H6 28801345 DTRPRFLEYSTSECHFFNGTERVRFLERYFHNQEENVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA 6ati B 1.98 BS01 III C 1 E9 F26 Y30 N37 V38 D57 Y60 W61 Q70 R71 A74 Y78 H81 N82 V85 G86 E8 F25 Y29 N36 V37 D56 Y59 W60 Q69 R70 A73 Y77 H80 N81 V84 G85 A0A0A1I7H6 28801345 DTRPRFLEYSTSECHFFNGTERVRFLERYFHNQEENVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAT 6ati E 1.98 BS01 III F 1 E9 S13 F26 Y30 N37 D57 Y60 W61 Q70 R71 Y78 H81 N82 V85 G86 E8 S12 F25 Y29 N36 D56 Y59 W60 Q69 R70 Y77 H80 N81 V84 G85 A0A0A1I7H6 28801345 DTRPRFLEYSTSECHFFNGTERVRFLERYFHNQEENVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAT