5giq A 1.80 BS01 ZN A 1 D221 H285 E314 E328 D221 H284 E313 E327 Q9RUY4 SSKMDQLRPVLGRAGVDALWVSAPANVRWLSGFTSAEDGKVLVSPDGATLYTDARYTVQAQEESSLPQYIARPPATYEHAADTVRGLRVGFEAESLTVAELEDLRQAWPNSTLVALRGTLGGLRAVKTPEEIGAIRAAQDLADRVYTEVRPMIRAGVRELDVAVEIETRLRRAGGESAFELIVASGPNGAKPHGHASKRVIEDGDLVTIDMGARLGGYNSDMTRTVAVGTPSAEMKRVYDAVLEAEEAAIAAIRPGVRAADLDKLARDLLTRHGLGEAFHSLGHGVGLEVHEGPGLRGTSQDVLEAGMVITIEPGAYLPGVGGVRIEDLILVTEDGYEVLSHSAKESV 5giq A 1.80 BS02 ZN A 2 D210 D221 E328 D210 D221 E327 Q9RUY4 SSKMDQLRPVLGRAGVDALWVSAPANVRWLSGFTSAEDGKVLVSPDGATLYTDARYTVQAQEESSLPQYIARPPATYEHAADTVRGLRVGFEAESLTVAELEDLRQAWPNSTLVALRGTLGGLRAVKTPEEIGAIRAAQDLADRVYTEVRPMIRAGVRELDVAVEIETRLRRAGGESAFELIVASGPNGAKPHGHASKRVIEDGDLVTIDMGARLGGYNSDMTRTVAVGTPSAEMKRVYDAVLEAEEAAIAAIRPGVRAADLDKLARDLLTRHGLGEAFHSLGHGVGLEVHEGPGLRGTSQDVLEAGMVITIEPGAYLPGVGGVRIEDLILVTEDGYEVLSHSAKESV 5git A 2.19 BS01 XXT A 1 R135 K150 C151 R85 K100 C101 Q14145 TFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACADFLVQQLD 5gj0 A 2.40 BS01 HEM A 1 T72 Y87 Q88 R89 L190 H192 T193 T204 A205 A206 Y225 L283 T34 Y49 Q50 R51 L152 H154 T155 T166 A167 A168 Y187 L245 B4EKB3 SKRVIVIGGALAETAFALGGAETPRYRLVGADTTCTYPDAAKRLPKVGYQRALSAEGLLSLRPDLVLASAEAGPPTAIAQVKGAGVTVTTFDERHDVESVRAKITGVAQALDVRDAGAALLQRFDRDWQAARDAVAARVPGGAQPPRVLFVLNHTGTQALVAGQRTAADAMIRYAGARNAMQGFDHYKPLTTEALAAAAPDVVLISDEGLAAVGGHAALLATPGFGATPAGRARRVVSLDALFLLGFGPRLPLAVTTLHRRLSDALA 5gj1 A 1.50 BS01 HEM A 1 T71 T72 Y87 Q88 R89 E109 T37 T38 Y53 Q54 R55 E75 B4EKB3 GPLGSKRVIVIGGALAETAFALGGAETPRYRLVGADTTCTYPDAAKRLPKVGYQRALSAEGLLSLRPDLVLASAEAGPPTAIAQVKGAGVTVTTFDERHDVESVRAKITGVAQALDVRDAGAALLQRFDRDWQAARDAVAARVPGGAQPPRVLFVLNHTGTQALVAGQRTAADAMIRYAGARNAMQGFDHYKPLTTEALAAAAPDVVLISDEGLAAVGGHAALLATPGFGATPAGRARRVVSLDALFLLGFGPRLPLAVTTLHRRLSDALA 5gj1 A 1.50 BS02 HEM A 2 L190 Y225 L156 Y191 B4EKB3 GPLGSKRVIVIGGALAETAFALGGAETPRYRLVGADTTCTYPDAAKRLPKVGYQRALSAEGLLSLRPDLVLASAEAGPPTAIAQVKGAGVTVTTFDERHDVESVRAKITGVAQALDVRDAGAALLQRFDRDWQAARDAVAARVPGGAQPPRVLFVLNHTGTQALVAGQRTAADAMIRYAGARNAMQGFDHYKPLTTEALAAAAPDVVLISDEGLAAVGGHAALLATPGFGATPAGRARRVVSLDALFLLGFGPRLPLAVTTLHRRLSDALA 5gj1 B 1.50 BS01 HEM B 1 T71 Y87 R89 T34 Y50 R52 B4EKB3 GSKRVIVIGGALAETAFALGGAETPRYRLVGADTTCTYPDAAKRLPKVGYQRALSAEGLLSLRPDLVLASAEAGPPTAIAQVKGAGVTVTTFDERHDVESVRAKITGVAQALDVRDAGAALLQRFDRDWQAARDAVAARVPGGAQPPRVLFVLNHTGTQALVAGQRTAADAMIRYAGARNAMQGFDHYKPLTTEALAAAAPDVVLISDEGLAAVGGHAALLATPGFGATPAGRARRVVSLDALFLLGFGPRLPLAVTTLHRRLSDALA 5gj1 B 1.50 BS02 HEM B 2 T204 A205 A206 H224 Y225 L283 T167 A168 A169 H187 Y188 L246 B4EKB3 GSKRVIVIGGALAETAFALGGAETPRYRLVGADTTCTYPDAAKRLPKVGYQRALSAEGLLSLRPDLVLASAEAGPPTAIAQVKGAGVTVTTFDERHDVESVRAKITGVAQALDVRDAGAALLQRFDRDWQAARDAVAARVPGGAQPPRVLFVLNHTGTQALVAGQRTAADAMIRYAGARNAMQGFDHYKPLTTEALAAAAPDVVLISDEGLAAVGGHAALLATPGFGATPAGRARRVVSLDALFLLGFGPRLPLAVTTLHRRLSDALA 5gj2 A 2.40 BS01 MG A 1 D104 D160 D184 D11 D67 D91 A5UZ69 GSERIVSLNGDITEIIFALGMGEYVVGVDSSATYPPERTKMLPNIGYQRRLSAEGILSLNPTLVIGDEAAGPPETLAQIRAAGVPLAITADPPSLDAPQQKIRFVAQALGIPQRGERLAAQVEAEIAAARDLARRITNPPHVLFLYLRGTDVQQVAGRNTAVDVMIAAAGGINAAADAGIVEFKPLSPEVVIAAQPDVLLVLDKGLESVGGVDGLLKIPGLADTPAGRQRRIIALDDLYLLGMGPRTGQALTDLTIAFYDAAQ 5gj3 A 2.00 BS01 HEM A 1 S124 Y140 R142 R143 D330 S34 Y50 R52 R53 D240 A5UZ69 GPLGSERIVSLNGDITEIIFALGMGEYVVGVDSSATYPPERTKMLPNIGYQRRLSAEGILSLNPTLVIGDEAAGPPETLAQIRAAGVPLAITADPPSLDAPQQKIRFVAQALGIPQRGERLAAQVEAEIAAARDLARRITNPPHVLFLYLRGTDVQQVAGRNTAVDVMIAAAGGINAAADAGIVEFKPLSPEVVIAAQPDVLLVLDKGLESVGGVDGLLKIPGLADTPAGRQRRIIALDDLYLLGMGPRTGQALTDLTIAFYDAAQGSRP 5gj3 A 2.00 BS02 HEM A 2 Y239 R241 F276 L295 D330 L334 Y149 R151 F186 L205 D240 L244 A5UZ69 GPLGSERIVSLNGDITEIIFALGMGEYVVGVDSSATYPPERTKMLPNIGYQRRLSAEGILSLNPTLVIGDEAAGPPETLAQIRAAGVPLAITADPPSLDAPQQKIRFVAQALGIPQRGERLAAQVEAEIAAARDLARRITNPPHVLFLYLRGTDVQQVAGRNTAVDVMIAAAGGINAAADAGIVEFKPLSPEVVIAAQPDVLLVLDKGLESVGGVDGLLKIPGLADTPAGRQRRIIALDDLYLLGMGPRTGQALTDLTIAFYDAAQGSRP 5gj3 A 2.00 BS04 ZN A 2 H234 D270 H144 D180 A5UZ69 GPLGSERIVSLNGDITEIIFALGMGEYVVGVDSSATYPPERTKMLPNIGYQRRLSAEGILSLNPTLVIGDEAAGPPETLAQIRAAGVPLAITADPPSLDAPQQKIRFVAQALGIPQRGERLAAQVEAEIAAARDLARRITNPPHVLFLYLRGTDVQQVAGRNTAVDVMIAAAGGINAAADAGIVEFKPLSPEVVIAAQPDVLLVLDKGLESVGGVDGLLKIPGLADTPAGRQRRIIALDDLYLLGMGPRTGQALTDLTIAFYDAAQGSRP 5gmp A 2.80 BS01 F62 A 1 L718 V726 A743 M790 Q791 L792 M793 P794 G796 C797 R841 L844 L23 V31 A48 M95 Q96 L97 M98 P99 G101 C102 R146 L149 2.7.10.1 P00533 28033579 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPRALMDEEDMDDVVDADEYLIP 5gtc A 2.70 BS02 NUC J 1 H39 R40 Y41 P43 G44 T45 V46 A47 R49 K56 R63 K64 L65 P66 R69 D81 R83 H2 R3 Y4 P6 G7 T8 V9 A10 R12 K19 R26 K27 L28 P29 R32 D44 R46 P68431 28534629 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5gtc C 2.70 BS01 NUC I 1 A12 A14 K15 T16 R17 G28 R29 R32 R42 A2 A4 K5 T6 R7 G18 R19 R22 R32 P04908 28534629 RAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 5gtc D 2.70 BS01 NUC I 1 S32 G53 I54 S55 S56 R86 S87 T88 S1 G22 I23 S24 S25 R55 S56 T57 P06899 28534629 SRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5gtc G 2.70 BS03 III K 1 L23 A53 E56 Y57 E61 E64 L65 D90 E92 L12 A42 E45 Y46 E50 E53 L54 D79 E81 P04908 28534629 AKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 5gtc H 2.70 BS03 III K 1 Q47 E105 L106 H109 E113 K116 Q15 E73 L74 H77 E81 K84 P06899 28534629 RKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5h56 A 1.70 BS01 ADP A 1 G10 S11 G12 K13 T14 T15 R139 K143 R145 G176 E177 E178 G10 S11 G12 K13 T14 T15 R139 K143 R145 G176 E177 E178 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLR 5h56 A 1.70 BS02 TYD A 1 D9 K13 E36 R47 L51 F64 R90 T95 Y98 Q99 R145 D9 K13 E36 R47 L51 F64 R90 T95 Y98 Q99 R145 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLR 5h56 A 1.70 BS03 MG A 1 E57 K103 E57 K103 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLR 5h56 A 1.70 BS04 MG A 2 I96 N114 I96 N114 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLR 5h5b B 2.05 BS01 FLC B 1 D9 G10 S11 G12 K13 T14 T15 R145 D9 G10 S11 G12 K13 T14 T15 R145 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLR 5h5k A 2.30 BS01 ATP A 1 D9 G10 S11 G12 K13 T14 T15 R90 R139 R145 G176 E177 E178 D9 G10 S11 G12 K13 T14 T15 R90 R139 R145 G176 E177 E178 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVL 5h5k A 2.30 BS02 C5P A 1 D9 R47 F64 R90 S94 T95 Y98 R145 D9 R47 F64 R90 S94 T95 Y98 R145 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVL 5h5k B 2.30 BS02 C5P B 1 D9 R47 F64 R90 S94 T95 Y98 Q99 D9 R47 F64 R90 S94 T95 Y98 Q99 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVL 5h75 A 2.74 BS01 FAD A 1 G17 S18 T43 T45 D48 L49 T91 A92 N93 N105 N123 M124 M128 G10 S11 T36 T38 D41 L42 T74 A75 N76 N88 N106 M107 M111 4.1.1.- P38507 28572639 DKKLLIGICGSISSVGISSYLLYFKSFFKEIRVVMTKTAEDLIPAHTVSYFCDHVYSEHEIGRWADIYCIIPATANILGQTANGVAMNLVATTVLAHPHNTIFFPNMNDLMWNKTVVSRNIEQLRKDGHIVIEPVEIMAFEIATGTRKPNRGLITPDKALLAIEQGFAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDAQA 5h75 A 2.74 BS02 FAD B 1 E65 A103 M104 T109 E58 A86 M87 T92 4.1.1.- P38507 28572639 DKKLLIGICGSISSVGISSYLLYFKSFFKEIRVVMTKTAEDLIPAHTVSYFCDHVYSEHEIGRWADIYCIIPATANILGQTANGVAMNLVATTVLAHPHNTIFFPNMNDLMWNKTVVSRNIEQLRKDGHIVIEPVEIMAFEIATGTRKPNRGLITPDKALLAIEQGFAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDAQA 5h75 B 2.74 BS01 FAD B 1 C16 G17 T43 K44 T45 T91 A92 N93 N105 N123 M124 C10 G11 T37 K38 T39 T75 A76 N77 N89 N107 M108 4.1.1.- P38507 28572639 KDKKLLIGICGSISSVGISSYLLYFKSFFKEIRVVMTKTAEDLIPAHTVSYFCDHVYSEHEIGRWADIYCIIPATANILGQTANGVAMNLVATTVLAHPHNTIFFPNMNDLMWNKTVVSRNIEQLRKDGHIVIEPVEIRGLITPDKALLAIEQGFAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDAQA 5h75 B 2.74 BS02 FAD C 1 A103 M104 T109 A87 M88 T93 4.1.1.- P38507 28572639 KDKKLLIGICGSISSVGISSYLLYFKSFFKEIRVVMTKTAEDLIPAHTVSYFCDHVYSEHEIGRWADIYCIIPATANILGQTANGVAMNLVATTVLAHPHNTIFFPNMNDLMWNKTVVSRNIEQLRKDGHIVIEPVEIRGLITPDKALLAIEQGFAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDAQA 5h75 C 2.74 BS02 FAD C 1 C16 G17 S18 I19 T43 T45 T91 A92 N93 N105 N123 M124 M128 C12 G13 S14 I15 T39 T41 T77 A78 N79 N91 N109 M110 M114 4.1.1.- P38507 28572639 ILKDKKLLIGICGSISSVGISSYLLYFKSFFKEIRVVMTKTAEDLIPAHTVSYFCDHVYSEHEIGRWADIYCIIPATANILGQTANGVAMNLVATTVLAHPHNTIFFPNMNDLMWNKTVVSRNIEQLRKDGHIVIEPVEIRGLITPDKALLAIEQGFAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDAQA 5h75 D 2.74 BS01 FAD D 1 C16 G17 S18 T43 T45 L49 T91 A92 N93 M104 N105 N123 M124 M128 I159 C20 G21 S22 T47 T49 L53 T87 A88 N89 M100 N101 N119 M120 M124 I155 4.1.1.- P38507 28572639 GGGSMSISILKDKKLLIGICGSISSVGISSYLLYFKSFFKEIRVVMTKTAEDLIPAHTVSYFCDHVYSEHHVEIGRWADIYCIIPATANILGQTANGVAMNLVATTVLAHPHNTIFFPNMNDLMWNKTVVSRNIEQLRKDGHIVIEPVEIMAFEIATGTRKPNRGLITPDKALLAIEQGFAFYEILHLPNLNEEQRNAFIQSLKDDPSQSANLLAEAKKLNDAQA 5h7d E 2.57 BS01 CA E 1 D165 D167 D169 T171 E176 D59 D61 D63 T65 E70 O16305 28572639 KETQEASWEIFTLPNLNGRQVAAFISSLLDDPSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 5h7d E 2.57 BS02 CA E 2 D201 D203 N205 T207 D209 E212 D95 D97 N99 T101 D103 E106 O16305 28572639 KETQEASWEIFTLPNLNGRQVAAFISSLLDDPSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 5h7d F 2.57 BS02 CA F 2 D201 D203 N205 T207 E212 D95 D97 N99 T101 E106 O16305 28572639 KETQEASWEIFTLPNLNGRQVAAFISSLLDDPSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 5hw1 A 1.70 BS01 XE A 1 L40 V44 I263 T265 Q278 I279 I282 L15 V19 I236 T238 Q251 I252 I255 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 5hw1 A 1.70 BS02 XE A 2 L51 L194 I208 A249 P257 L26 L169 I183 A223 P230 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 5hw1 A 1.70 BS03 XE A 3 L221 A224 L225 L250 G283 L286 I287 L196 A199 L200 L224 G256 L259 I260 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 5hw1 B 1.70 BS02 XE B 2 L51 L194 T195 I208 A249 P257 L26 L169 T170 I183 A223 P230 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 5hw1 C 1.70 BS03 XE C 3 L221 A224 L225 L250 G283 I287 L196 A199 L200 L224 G256 I260 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 5hw5 B 1.41 BS04 XE B 4 P27 E28 V31 P2 E3 V6 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 5i63 A 1.95 BS01 XE A 1 L40 V44 T265 Q278 I279 L15 V19 T238 Q251 I252 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW 5i63 A 1.95 BS02 XE A 2 Y46 L221 I246 N263 I279 Y21 L196 I220 N236 I252 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW 5i63 B 1.95 BS01 XE B 1 L40 V44 N263 T265 Q278 I279 L15 V19 N236 T238 Q251 I252 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW 5i63 B 1.95 BS02 XE B 2 L221 I246 V261 N263 I279 L196 I220 V234 N236 I252 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW 5i63 C 1.95 BS01 XE C 1 A36 L40 V44 N263 Q278 I279 I282 A11 L15 V19 N236 Q251 I252 I255 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW 5i63 C 1.95 BS02 XE C 2 L221 V261 N263 I279 I282 G283 L196 V234 N236 I252 I255 G256 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW 5i63 D 1.95 BS01 XE D 1 A36 L40 V44 N263 T265 Q278 I279 I282 A11 L15 V19 N236 T238 Q251 I252 I255 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW 5i63 D 1.95 BS02 XE D 2 L221 V261 I279 I282 G283 L196 V234 I252 I255 G256 3.5.2.6 P62593 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW 5isp X 1.84 BS02 U06 X 1 L5 V6 A7 N18 Q19 L20 D27 L28 V31 T46 S49 I50 F92 Y98 L5 V6 A7 N18 Q19 L20 D27 L28 V31 T46 S49 I50 F92 Y98 1.5.1.3 P0A017 27308944 TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLYEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK 5ist X 1.72 BS01 U06 X 1 L5 V6 A7 N18 Q19 L20 D27 L28 V31 S49 I50 L54 F92 L5 V6 A7 N18 Q19 L20 D27 L28 V31 S49 I50 L54 F92 1.5.1.3 P0A017 27308944 TLSILVAHDLQRVIGFENQLPWHLPNDLKNVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK 5ist X 1.72 BS02 XNP X 1 I14 N18 Q19 L20 G43 R44 K45 T46 L62 T63 S64 G94 Q95 T96 L97 E100 T121 I14 N18 Q19 L20 G43 R44 K45 T46 L62 T63 S64 G94 Q95 T96 L97 E100 T121 1.5.1.3 P0A017 27308944 TLSILVAHDLQRVIGFENQLPWHLPNDLKNVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK 5jxd A 2.03 BS01 6OU A 1 T40 T41 S47 V50 L51 L75 V79 H86 R87 F102 K103 F162 L171 I189 N197 I198 T28 T29 S35 V38 L39 L63 V67 H74 R75 F90 K91 F150 L159 I177 N185 I186 Q921Z5 TDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAERVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHEIIQRHLTAKSHGRVNNVFDHFSDSDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI 5k97 A 2.10 BS01 NUC D 1 F42 I44 A45 V46 R47 M65 Y69 R70 R73 K128 S197 R239 G240 I241 G242 P243 K244 R245 F41 I43 A44 V45 R46 M64 Y68 R69 R72 K127 S196 R238 G239 I240 G241 P242 K243 R244 3.1.-.- P39748 GIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSNYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTLEVLFQ 5k97 A 2.10 BS02 NUC E 1 G2 M37 Y40 K93 E160 D179 D181 N233 R245 Y268 G1 M36 Y39 K92 E159 D178 D180 N232 R244 Y267 3.1.-.- P39748 GIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSNYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTLEVLFQ 5k97 A 2.10 BS03 NUC F 1 R47 Q48 L53 Q54 T61 M65 K314 Q315 F316 S317 R320 R46 Q47 L52 Q53 T60 M64 K313 Q314 F315 S316 R319 3.1.-.- P39748 GIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSNYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTLEVLFQ 5k97 A 2.10 BS04 NUC G 1 D86 G87 K88 L97 R100 S101 K132 D85 G86 K87 L96 R99 S100 K131 3.1.-.- P39748 GIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSNYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTLEVLFQ 5ki9 A 1.60 BS01 TFA A 1 R14 R16 R20 R14 R16 R20 Q8WTQ1 EFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDES 5kjx A 1.90 BS01 CMP A 1 V283 V302 Q304 F324 G325 E326 I327 A328 R335 A336 A337 V339 Y373 N374 S375 V43 V62 Q64 F84 G85 E86 I87 A88 R95 A96 A97 V99 Y133 N134 S135 P10644 28583991 RKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 5kjy A 2.00 BS01 CMP A 1 V283 V302 Q304 R316 F324 G325 E326 I327 A328 R335 T336 A337 Y373 N374 S375 V46 V65 Q67 R77 F85 G86 E87 I88 A89 R96 T97 A98 Y134 N135 S136 P10644 28583991 STLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSEEFVEVRRLGPSDYFGEIALLMNRPRTATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSL 5kjz A 1.35 BS01 PCG A 1 V302 Q304 V315 R316 F324 G325 E326 I327 A328 R335 T336 A337 Y373 V70 Q72 V83 R84 F92 G93 E94 I95 A96 R103 T104 A105 Y141 P10644 28583991 SILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVRRLGPSDYFGEIALLMNRPRTATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 5kks A 3.30 BS01 6U1 A 1 I82 R84 G85 A86 F87 G88 E89 V90 A103 K105 V137 M153 E154 Y155 M156 L205 A215 D216 F368 I77 R79 G80 A81 F82 G83 E84 V85 A98 K100 V132 M148 E149 Y150 M151 L200 A210 D211 F363 2.7.11.1 Q13464 SFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEETFPIPKAFVGNQLPFVGFTYYSNRRY 5kks B 3.30 BS01 6U1 B 1 I82 R84 G85 A86 F87 G88 E89 V90 A103 K105 L107 F120 E124 V137 M153 E154 Y155 M156 L205 A215 D216 F368 I78 R80 G81 A82 F83 G84 E85 V86 A99 K101 L103 F116 E120 V133 M149 E150 Y151 M152 L201 A211 D212 F364 2.7.11.1 Q13464 MSFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEGEEETFPIPKAFVGNQLPFVGFTYYSN 5kkt A 2.80 BS01 6U2 A 1 I82 G85 A86 F87 G88 E89 V90 A103 K105 L107 F120 V137 M153 E154 Y155 M156 L205 A215 D216 G218 F368 I77 G80 A81 F82 G83 E84 V85 A98 K100 L102 F111 V128 M144 E145 Y146 M147 L196 A206 D207 G209 F359 2.7.11.1 Q13464 SFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLETFPIPKAFVGNQLPFVGFTYYSNRRY 5kly B 1.30 BS01 6UR A 1 M121 W123 M107 W109 3.-.-.- P49773 GDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVNLHVLGGRQMHWPPG 5km2 A 1.25 BS01 C5P A 1 I18 F19 D43 I44 S45 L53 N99 S107 V108 H112 H114 I7 F8 D32 I33 S34 L42 N88 S96 V97 H101 H103 3.-.-.- P49773 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 5km4 A 1.40 BS01 IU A 1 I18 F19 D43 I44 S45 L53 N99 G105 Q106 S107 V108 H112 H114 I7 F8 D32 I33 S34 L42 N88 G94 Q95 S96 V97 H101 H103 3.-.-.- P49773 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 5km5 B 2.10 BS01 TR5 B 1 F56 I59 L64 F78 R79 D80 V81 A82 N136 A142 S144 V145 H149 H151 F5 I8 L13 F27 R28 D29 V30 A31 N85 A91 S93 V94 H98 H100 3.-.-.- Q9BX68 APTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIHVLGGRQLQWPPG 5km6 A 1.60 BS01 6US A 1 I18 F19 F41 H42 D43 I44 N99 G105 Q106 S107 V108 N112 H114 I3 F4 F26 H27 D28 I29 N84 G90 Q91 S92 V93 N97 H99 3.-.-.- P49773 DTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVNLHVLGGRQMHWPPG 5km7 A 1.25 BS01 D5M A 1 F19 F41 H42 D43 I44 L53 N99 G105 Q106 S107 V108 H112 H114 F6 F28 H29 D30 I31 L40 N86 G92 Q93 S94 V95 H99 H101 3.-.-.- P49773 GGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 5km8 B 2.00 BS01 L8P B 1 N136 A142 Q143 S144 V145 H149 H151 N85 A91 Q92 S93 V94 H98 H100 3.-.-.- Q9BX68 APTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIHVLGGRQLQWPPG 5km9 B 1.45 BS01 ADN B 1 F56 I59 L64 F78 R79 D80 V81 A82 L90 Q143 V145 H151 F5 I8 L13 F27 R28 D29 V30 A31 L39 Q92 V94 H100 3.-.-.- Q9BX68 APTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIHVLGGRQLQWPPG 5kmc A 1.35 BS01 6UU A 1 I18 F19 F41 D43 I44 L53 N99 Q106 S107 V108 H112 H114 I7 F8 F30 D32 I33 L42 N88 Q95 S96 V97 H101 H103 3.-.-.- P49773 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 5kse A 2.11 BS01 NUC D 1 Q41 F42 I44 A45 V46 M65 Y69 R70 R73 S197 K201 R239 G240 G242 P243 K244 R245 R320 Q40 F41 I43 A44 V45 M64 Y68 R69 R72 S196 K200 R238 G239 G241 P242 K243 R244 R319 3.1.-.- P39748 GIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKASERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTLEVLFQ 5kse A 2.11 BS02 NUC E 1 G2 I3 A7 M37 Y40 L97 A100 S101 R104 K132 V133 T134 K135 E160 E178 D179 R192 R245 K267 Y268 G1 I2 A6 M36 Y39 L96 A99 S100 R103 K131 V132 T133 K134 E159 E177 D178 R191 R244 K266 Y267 3.1.-.- P39748 GIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKASERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTLEVLFQ 5l6x A 2.00 BS01 AZI A 1 R13 I104 R14 I105 2.5.1.18 P09211 MAPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ 5l6x A 2.00 BS04 AZI A 4 D57 G58 D58 G59 2.5.1.18 P09211 MAPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ 5l6x A 2.00 BS05 6SG A 1 Y7 F8 V10 R13 V35 W38 K44 Q51 L52 Q64 S65 Y108 G205 Y8 F9 V11 R14 V36 W39 K45 Q52 L53 Q65 S66 Y109 G206 2.5.1.18 P09211 MAPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ 5l6x A 2.00 BS06 AZI B 1 R74 Y79 R75 Y80 2.5.1.18 P09211 MAPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ 5l9c A 1.85 BS01 CBI A 1 E142 Y179 W183 Y209 D213 G214 S215 E132 Y169 W173 Y199 D203 G204 S205 SSFEWFGSNESGAEFGSGNIPGVEGTDYTFPNTTAIQILIDAGMNIFRVPFLMERMIPTEMTGSLDTAYFEGYSEVINYITGKGAHAVVDPHNFGRYYGTPISSTSDFQTFWSTLASQFKSNDLVIFDTNNEYHDMDESVVVALNQAAIDGIRDAGATTQYIFVEGNAYSGAWTWTTYNTAMVNLTDPSDLIVYEMHQYLDSDGSGTSDQCVSSTVGQERVVDATTWLQSNGKLGILGEFAGGANSVCEEAVEGMLDYLAENSDVWLGASWWSAGPWWQDYIYSMEPPNGIAYESYLSILETYF 5l9c A 1.85 BS02 CBI A 2 E24 F25 G26 W282 W288 Y291 E14 F15 G16 W272 W278 Y281 SSFEWFGSNESGAEFGSGNIPGVEGTDYTFPNTTAIQILIDAGMNIFRVPFLMERMIPTEMTGSLDTAYFEGYSEVINYITGKGAHAVVDPHNFGRYYGTPISSTSDFQTFWSTLASQFKSNDLVIFDTNNEYHDMDESVVVALNQAAIDGIRDAGATTQYIFVEGNAYSGAWTWTTYNTAMVNLTDPSDLIVYEMHQYLDSDGSGTSDQCVSSTVGQERVVDATTWLQSNGKLGILGEFAGGANSVCEEAVEGMLDYLAENSDVWLGASWWSAGPWWQDYIYSMEPPNGIAYESYLSILETYF 5l9c B 1.85 BS01 CBI B 1 E142 Y179 W183 Y209 D213 S215 E132 Y169 W173 Y199 D203 S205 SSFEWFGSNESGAEFGSGNIPGVEGTDYTFPNTTAIQILIDAGMNIFRVPFLMERMIPTEMTGSLDTAYFEGYSEVINYITGKGAHAVVDPHNFGRYYGTPISSTSDFQTFWSTLASQFKSNDLVIFDTNNEYHDMDESVVVALNQAAIDGIRDAGATTQYIFVEGNAYSGAWTWTTYNTAMVNLTDPSDLIVYEMHQYLDSDGSGTSDQCVSSTVGQERVVDATTWLQSNGKLGILGEFAGGANSVCEEAVEGMLDYLAENSDVWLGASWWSAGPWWQDYIYSMEPPNGIAYESYLSILETYF 5lg7 A BS02 ZN A 2 C35 M36 H37 C54 C57 C35 M36 H37 C54 C57 6.3.2.- Q6ZNA4 MKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQRLITNKKCPICRVDIEAQLPSES 5lhp A 2.63 BS01 PBZ A 1 D189 S190 S195 V213 W215 G216 G218 C220 G226 D193 S194 S199 V217 W219 G220 G222 C223 G230 3.4.21.73 P06869 28611361 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVYLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLDWIQSHIG 5lhq A 2.60 BS01 0GJ A 1 H57 Y99 D189 S190 C191 K192 G193 S195 V213 S214 W215 G216 G218 H47 Y95 D193 S194 C195 K196 G197 S199 V217 S218 W219 G220 G222 3.4.21.73 P06869 28611361 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVYLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLDWIQSHIG 5lqv A BS01 PGM A 1 T8 L11 L15 L18 L35 L36 A48 C49 L52 K53 A55 A56 S58 I59 L62 A67 I82 T84 T8 L11 L15 L18 L35 L36 A48 C49 L52 K53 A55 A56 S58 I59 L62 A67 I82 T84 A0AT29 28266846 AISCGAVTSDLSPCLTYLTGGPGPSPQCCGGVKKLLAAANTTPDRQAACNCLKSAAGSITKLNTNNAAALPGKCGVNIPYKISTTTNCNTVKF 5lvw A 2.90 BS01 FAD A 1 W87 S121 V122 F123 Y144 T146 W186 T367 H371 W83 S117 V118 F119 Y140 T142 W182 T363 H367 I7IIA9 RSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5lvw A 2.90 BS02 IND A 1 L98 S121 F123 I237 M373 L94 S117 F119 I233 M369 I7IIA9 RSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5lwk A 2.11 BS01 BEF A 1 D54 I55 R56 T82 A83 D54 I55 R56 T82 A83 28577341 MTNILIVEDDPMVQFIHRNYLEKIGTFDTIYSSETIADAKKLLASRSIQLVLLDIRLKDGNGIDFLTDLRRTKQTVDVILITAANEVNIVNDALHLGVIDYLIKPFTLERFEKSIQRYRTKH 5lwk A 2.11 BS02 MG A 1 D9 D54 R56 D9 D54 R56 28577341 MTNILIVEDDPMVQFIHRNYLEKIGTFDTIYSSETIADAKKLLASRSIQLVLLDIRLKDGNGIDFLTDLRRTKQTVDVILITAANEVNIVNDALHLGVIDYLIKPFTLERFEKSIQRYRTKH 5lwl A 3.10 BS01 SO4 A 1 I55 R56 T82 A83 I56 R57 T83 A84 28577341 AATNILIVEDDPMVQFIHRNYLEKIGTFDTIYSSETIADAKKLLASRSIQLVLLAIRLKDGNGIDFLTDLRRTKQTVDVILITAANEVNIVNDALHLGVIDYLIKPFTLERFEKSIQRYRTK 5lwl B 3.10 BS01 SO4 B 1 A54 I55 R56 T82 A83 A55 I56 R57 T83 A84 28577341 AATNILIVEDDPMVQFIHRNYLEKIGTFDTIYSSETIADAKKLLASRSIQLVLLAIRLKDGNGIDFLTDLRRTKQTVDVILITAANEVNIVNDALHLGVIDYLIKPFTLERFEKSIQRYRTK 5m23 A 1.97 BS01 7DC A 1 A47 S49 A65 G89 I90 S91 D107 Y131 F133 K259 Y260 C261 F263 I305 A15 S17 A33 G57 I58 S59 D75 Y99 F101 K227 Y228 C229 F231 I273 P61964 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 5m3z A 1.45 BS02 NLE A 1 Y113 H115 K210 V338 S339 R374 Y111 H113 K208 V336 S337 R372 4.4.1.11 A0A0A5P8W7 28602917 DCRTYGFNTQIVHAGQQPDPSTGALSTPIFQTSTFVFDSAEQGAARFALEESGYIYTRLGNPTTDALEKKLAVLERGEAGLATASGISAITTTLLTLCQQGDHIVSASAIYGHTHAFLSHSMPKFGINVSFVDAAKPEEIRAAMRPETKVVYIETPANPTLSLVDIETVAGIAHQQGALLVVDNTFMSPYCQQPLQLGADIVVHSVTKYINGHGDVIGGIIVGKQEFIDQARFVGLKDITGGCMSPFNAWLTLRGVKTLGIRMERHCENALKIARFLEGHPSITRVYYPGLSSHPQYELGQRQMSLPGGIISFEIAGGLEAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPEERLKAGITDGLIRLSVGLEDPEDIINDLEHAIRKAT 5m3z A 1.45 BS03 PY6 A 1 S87 G88 I89 Y113 H115 E156 D185 T187 S207 T209 K210 V338 S339 R374 S85 G86 I87 Y111 H113 E154 D183 T185 S205 T207 K208 V336 S337 R372 4.4.1.11 A0A0A5P8W7 28602917 DCRTYGFNTQIVHAGQQPDPSTGALSTPIFQTSTFVFDSAEQGAARFALEESGYIYTRLGNPTTDALEKKLAVLERGEAGLATASGISAITTTLLTLCQQGDHIVSASAIYGHTHAFLSHSMPKFGINVSFVDAAKPEEIRAAMRPETKVVYIETPANPTLSLVDIETVAGIAHQQGALLVVDNTFMSPYCQQPLQLGADIVVHSVTKYINGHGDVIGGIIVGKQEFIDQARFVGLKDITGGCMSPFNAWLTLRGVKTLGIRMERHCENALKIARFLEGHPSITRVYYPGLSSHPQYELGQRQMSLPGGIISFEIAGGLEAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPEERLKAGITDGLIRLSVGLEDPEDIINDLEHAIRKAT 5mkw A 2.00 BS01 ZN A 1 C20 C23 C96 C99 C20 C23 C96 C99 3.6.4.-,3.1.-.- Q5FWF4 28621305 SMSNNSYLRAKVFETEHGVCQLCNVNAQELFLRLRDAPKSQRKNLLYATWTSKLPLEQLNEMIRNPGEGHFWQVDHIKPVYGGGGQCSLDNLQTLCTVCHKERTARQAKERSQVRRQSL 5mr6 A 2.40 BS01 FAD A 1 W87 N91 S121 V122 F123 A124 Y144 T146 W186 T367 R370 H371 A372 M373 W86 N90 S120 V121 F122 A123 Y143 T145 W185 T366 R369 H370 A371 M372 I7IIA9 TDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5mr6 A 2.40 BS02 GOL A 1 S121 F123 M240 S120 F122 M239 I7IIA9 TDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5mr6 A 2.40 BS03 FAD D 1 A269 P270 A349 A268 P269 A348 I7IIA9 TDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5mr6 D 2.40 BS03 GOL D 1 S121 F123 M240 M373 S120 F122 M239 M372 I7IIA9 TDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5mr6 F 2.40 BS03 FAD G 1 A269 A349 A268 A348 I7IIA9 TDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5mr6 G 2.40 BS03 GOL G 1 S121 M240 M373 S120 M239 M372 I7IIA9 TDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5mr6 N 2.40 BS02 GOL N 1 L98 S121 F123 M240 M373 L97 S120 F122 M239 M372 I7IIA9 TDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5mr6 T 2.40 BS03 GOL T 1 F123 M240 M373 F122 M239 M372 I7IIA9 TDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVNGSNLLASKFPRAALDEVFGDAPGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPARDLTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDANTAARHAMLNVHVGHELYGGSFFGLDPIVPSL 5mwe A 2.02 BS01 III C 1 V1122 D1125 I1126 Q1129 K1132 T1133 V1136 V41 D44 I45 Q48 K51 T52 V55 P54623 28575671 HDCAKVDLENAELRRKLIRTKRAFEDTYEKLRMANKAKAQVEKDIKNQILKTHNVLRNV 5mwe A 2.02 BS02 III D 1 E1123 I1126 Q1129 I1130 T1133 H1134 V1136 L1137 E42 I45 Q48 I49 T52 H53 V55 L56 P54623 28575671 HDCAKVDLENAELRRKLIRTKRAFEDTYEKLRMANKAKAQVEKDIKNQILKTHNVLRNV 5mwe A 2.02 BS04 TCE B 1 A1115 K1119 A34 K38 P54623 28575671 HDCAKVDLENAELRRKLIRTKRAFEDTYEKLRMANKAKAQVEKDIKNQILKTHNVLRNV 5mwe B 2.02 BS01 III C 1 E1123 I1126 Q1129 I1130 T1133 H1134 L1137 E43 I46 Q49 I50 T53 H54 L57 P54623 28575671 SHDCAKVDLENAELRRKLIRTKRAFEDTYEKLRMANKAKAQVEKDIKNQILKTHNVLRNVR 5mwe B 2.02 BS02 III D 1 D1125 I1126 Q1129 K1132 T1133 V1136 V1140 D45 I46 Q49 K52 T53 V56 V60 P54623 28575671 SHDCAKVDLENAELRRKLIRTKRAFEDTYEKLRMANKAKAQVEKDIKNQILKTHNVLRNVR 5mwe B 2.02 BS04 TCE B 1 A1115 A1118 K1119 E1123 A35 A38 K39 E43 P54623 28575671 SHDCAKVDLENAELRRKLIRTKRAFEDTYEKLRMANKAKAQVEKDIKNQILKTHNVLRNVR 5my4 A 2.21 BS01 III C 1 S96 H98 V99 P101 S96 H98 V99 P101 28623233 DVVMTQTPLSLPVSLGDQASISCRSSQSLVHSDGNTYLHWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCSQSTHVPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5my4 B 2.21 BS01 III C 1 D31 W47 F50 S52 N53 L54 A55 Y56 Y59 Y99 Y101 I104 L105 D106 D31 W47 F50 S52 N53 L54 A55 Y56 Y59 Y99 Y101 I104 L105 D106 28623233 EVKLVESGGGLVQPGGSRKLSCAASGFTFSDYGMAWVRQAPGKGPEWVAFISNLAYSIYYADTVTGRFTISRENAKNTLYLEMSSLRSEDTAMYYCARYDYDNILDYVMDYWGQGTSVTVSSAKTTPPSVYPLAPGGSSVTLGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSQTVTCSVAHPASSTTVDKKLEPS 5myo A 1.59 BS01 III E 1 Y37 N39 R51 V94 G96 T97 F101 F103 Y37 N39 R51 V94 G96 T97 F101 F103 28623233 DVVMTQTPLTLSVTIGQPASISCKSSQSLLYSDGKTYLNWLLQRPGQSPMRLIYLVSKLDSGVPDRFTGSGSGTDFTLKISRVEAEDLGVYYCVQGTHFPFTFGSGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 5myo B 1.59 BS01 III E 1 T33 N35 V37 L50 N52 T97 R98 E99 A100 K101 E103 T107 W109 T33 N35 V37 L50 N52 T97 R98 E99 A100 K101 E103 T107 W109 28623233 EVQLQQSGPELVKPGASMKISCKASGYSFTGYTMNWVKQSHGKNLEWIGLINPYNGVTRYNQKFKGKATLIVDKSSSTAYMELLSLTSEDSAVYYCTREAKREWDETYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDC 5myx A 1.49 BS01 III E 1 Y31 K35 Y37 N39 R51 Y54 V55 V94 G96 T97 F99 F101 F103 Y31 K35 Y37 N39 R51 Y54 V55 V94 G96 T97 F99 F101 F103 28623233 DVVLTQTPLTLSVTIGQPASISCKSSQSLLYSNGKTYLNWLLQRPGQSPKRLIYVVSKLDSGVPDRFTGSGSGTDFTLKISRVEAEDLGVYYCVQGTHFPFTFGSGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 5myx B 1.49 BS01 III E 1 N31 W33 N35 W47 Y52 E99 G100 Y101 V103 W105 N30 W32 N34 W46 Y51 E98 G99 Y100 V102 W104 28623233 VQLQQSGAELVRPGSSVKISCKASGYIFNNYWINWVKQRPGQGLEWIGQIYPGDGDTNYNGKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYFCAREGYIVYWGQGTLVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDC 5myx D 1.49 BS01 III F 1 N31 Y32 W33 N35 W47 Y52 D55 D57 E99 G100 Y101 V103 W105 N30 Y31 W32 N34 W46 Y51 D54 D56 E98 G99 Y100 V102 W104 28623233 VQLQQSGAELVRPGSSVKISCKASGYIFNNYWINWVKQRPGQGLEWIGQIYPGDGDTNYNGKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYFCAREGYIVYWGQGTLVTVSAAKTTPPSVYPLAPSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR 5n2d A 2.35 BS01 8J8 B 1 A18 F19 T20 I54 Y56 M115 I116 S117 A121 D122 Y123 A1 F2 T3 I37 Y39 M98 I99 S100 A104 D105 Y106 Q9NZQ7 28613862 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHHH 5n2d B 2.35 BS01 8J8 B 1 I54 Y56 Q66 V68 M115 I116 S117 A121 I37 Y39 Q49 V51 M98 I99 S100 A104 Q9NZQ7 28613862 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHH 5n2d C 2.35 BS01 8J8 D 1 T20 I54 Y56 M115 I116 A121 D122 Y123 K124 T3 I37 Y39 M98 I99 A104 D105 Y106 K107 Q9NZQ7 28613862 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHHHHH 5n2f A 1.70 BS01 8HW B 1 F19 T20 I54 Y56 Q66 M115 A121 D122 F2 T3 I37 Y39 Q49 M98 A104 D105 Q9NZQ7 28613862 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHHHH 5n2f B 1.70 BS01 8HW B 1 I54 Y56 Q66 V68 M115 I116 S117 A121 D122 I37 Y39 Q49 V51 M98 I99 S100 A104 D105 Q9NZQ7 28613862 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHH 5n7j A 2.00 BS01 MLR A 1 A362 T363 E365 D413 H414 F417 F426 A362 T363 E365 D413 H414 F417 F426 2.4.1.4 Q9ZEU2 SPNSQYLKTRILDIYTPEQRAGIEKSEDWRQFSRRMDTHFPKLMNELDSVYGNNEALLPMLEMLLAQAWQSYSQRNSSLKDIDIARENNPDWILSNKQVGGVCYVDLFAGDLKGLKDKIPYFQELGLTYLHLMPLFKCPEGKSDGGYAVSSYRDVNPALGTIGDLREVIAALHEAGISAVVDFIFNHTSNEHEWAQRCAAGDPLFDNFYYIFPDRRMPDQYDRTLKEVFPDQHPGGFSQLEDGRWVWTTFNSFQWDLNYSNPWVFRAMAGEMLFLANLGVDILRMDAVIYIWKQMGTSCINLPQAHALIRAFNAVMRIAAPAVFFKSEAITHPDQVVQYIGQDECQIGYNPLQMALLWNTLATREVNLLHQALTYRHNLPEHTAWVNYVRSHDDIGWTFADEDAAYLGISGYDHRQFLNRFFVNRFDGSFARGVPFSYDPSTGDARVSGTAAALVGLAQDDPHAVDRIKLLYSIALSTGGLPLIYLGDEVGTLNDDDWSQDSNKSDDSRWAHRPRYNEALYAQRNDPSTAAGQIYQDLRHMIAVRQSNPRFDGGRLVTFNTNNKHIIGYIRNNALLAFGNFSEYPQTVTAHTLQAMPFKAHDLIGGKTVSLNQDLTLQPYQVMWLEIA 5n91 A 1.49 BS01 III F 1 Y16 W23 K69 N71 A73 T74 F77 Q79 R81 V86 Y18 W25 K71 N73 A75 T76 F79 Q81 R83 V88 Q8N8S7 GSMSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVL 5nar A 1.55 BS01 8RW A 1 H40 L41 C42 H57 W141 G142 I143 R151 C191 K192 G193 S195 T214 S215 G216 S217 R218 C220 H24 L25 C26 H41 W124 G125 I126 R133 C166 K167 G168 S170 T185 S186 G187 S188 R189 C191 3.4.21.46 P00746 28621538 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNTERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLASA 5nb6 A 1.75 BS01 8S2 A 1 H40 L41 C42 H57 W141 I143 R151 C191 K192 G193 S195 V213 T214 S215 G216 R218 C220 H24 L25 C26 H41 W124 I126 R133 C165 K166 G167 S169 V183 T184 S185 G186 R188 C190 3.4.21.46 P00746 28621538 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLASA 5nbw L 2.40 BS01 8SK L 1 N34 F36 T46 Y49 L89 Y91 N34 F36 T46 Y49 L89 Y91 28603847 DIELTQSPSSMYASLGERVTITCKASQDINSYLNWFQQKPGKSPKTLIYHTNRLVDGVPSRFSGSGSGQDYSLIISSLEFEDMGIYYCLQYDEFPYTFGGGTKLELKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 5nbw H 2.40 BS01 8SK L 1 E35 V37 K98 K99 Y100 G101 W104 E35 V37 K98 K99 Y100 G101 W104 28603847 EVKLHQSGAELVNPGASVKISCKAPGYTFNNYWIEWVKQRPGHGLEWIGEILPGSGRINYNEKFKDKATFTADTSSNTAYMQLSSLTSDDSAVYYCAKKYGDYWGQGTTVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDC 5nj8 A 3.30 BS01 NUC E 1 S36 R40 D65 K66 L67 S3 R7 D32 K33 L34 P35869 28602820 NPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWPPENSPLMERCFICRLRCLLDSSGFLAMNFQGKLKYLHGQKPQLALFAIATPL 5nj8 A 3.30 BS02 NUC F 1 R38 H39 R42 R5 H6 R9 P35869 28602820 NPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWPPENSPLMERCFICRLRCLLDSSGFLAMNFQGKLKYLHGQKPQLALFAIATPL 5nj8 A 3.30 BS03 ER3 B 1 L112 E116 L59 E63 P35869 28602820 NPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWPPENSPLMERCFICRLRCLLDSSGFLAMNFQGKLKYLHGQKPQLALFAIATPL 5nj8 B 3.30 BS01 NUC E 1 H94 E98 R101 H10 E14 R17 P27540 28602820 DKERLARENHSEIERRRRNKMTAYITELSDMVPTCPDKLTILRMAVSHMKSLRGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSSRRSFICRMRCHFVVVHCTGYIKAWPDDDPEAKFCLVAIGRLQV 5nj8 B 3.30 BS02 NUC F 1 R88 H94 E98 R102 T106 D127 K128 L129 R4 H10 E14 R18 T22 D37 K38 L39 P27540 28602820 DKERLARENHSEIERRRRNKMTAYITELSDMVPTCPDKLTILRMAVSHMKSLRGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSSRRSFICRMRCHFVVVHCTGYIKAWPDDDPEAKFCLVAIGRLQV 5nj8 B 3.30 BS03 ER3 B 2 E87 R91 E3 R7 P27540 28602820 DKERLARENHSEIERRRRNKMTAYITELSDMVPTCPDKLTILRMAVSHMKSLRGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSSRRSFICRMRCHFVVVHCTGYIKAWPDDDPEAKFCLVAIGRLQV 5nj8 C 3.30 BS01 NUC G 1 N34 S36 R40 N44 D65 K66 N3 S5 R9 N13 D34 K35 P35869 28602820 KSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQENSPLMERCFICRLRCLFLAMNFQGKLKYLHGQKKDGSILPPQLALFAIATP 5nj8 C 3.30 BS03 ER3 C 1 E165 E169 E116 E120 P35869 28602820 KSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQENSPLMERCFICRLRCLFLAMNFQGKLKYLHGQKKDGSILPPQLALFAIATP 5nj8 C 3.30 BS04 ER3 C 2 L112 Q113 E116 L63 Q64 E67 P35869 28602820 KSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQENSPLMERCFICRLRCLFLAMNFQGKLKYLHGQKKDGSILPPQLALFAIATP 5nj8 D 3.30 BS01 NUC G 1 H94 I97 E98 R101 H11 I14 E15 R18 P27540 28602820 ADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTSTDGSYKPSFLTDQELKHLILEAADFLFYVSDSVTPVQPQSESTLYDSRRSFICRMRCHCTGYIKALVAIGR 5nj8 D 3.30 BS02 NUC H 1 H94 S95 E98 R99 R102 T106 D127 K128 L129 H11 S12 E15 R16 R19 T23 D44 K45 L46 P27540 28602820 ADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTSTDGSYKPSFLTDQELKHLILEAADFLFYVSDSVTPVQPQSESTLYDSRRSFICRMRCHCTGYIKALVAIGR 5nj8 D 3.30 BS03 ER3 D 1 E92 N93 E9 N10 P27540 28602820 ADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTSTDGSYKPSFLTDQELKHLILEAADFLFYVSDSVTPVQPQSESTLYDSRRSFICRMRCHCTGYIKALVAIGR 5nkl A 1.70 BS02 NUC C 1 N483 N485 S486 Q489 I503 K505 S513 S515 A517 V518 S543 T544 T569 A570 T571 R573 S575 S576 S577 D578 N580 T664 F667 G668 Y671 G672 M673 S674 H676 R677 Q680 R728 R746 M747 N750 Q754 N191 N193 S194 Q197 I211 K213 S221 S223 A225 V226 S251 T252 T277 A278 T279 R281 S283 S284 S285 D286 N288 T372 F375 G376 Y379 G380 M381 S382 H384 R385 Q388 R436 R454 M455 N458 Q462 2.7.7.7 P19821 28594080 ALEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWIEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE 5nkl A 1.70 BS05 91T A 1 R573 D610 Y611 S612 Q613 I614 E615 H639 R659 R660 K663 F667 Y671 D785 R281 D318 Y319 S320 Q321 I322 E323 H347 R367 R368 K371 F375 Y379 D493 2.7.7.7 P19821 28594080 ALEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWIEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE 5nkl A 1.70 BS06 91R A 1 R573 V586 D610 Y611 S612 Q613 I614 E615 H639 R659 R660 K663 F667 Y671 D785 R281 V294 D318 Y319 S320 Q321 I322 E323 H347 R367 R368 K371 F375 Y379 D493 2.7.7.7 P19821 28594080 ALEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWIEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE 5nsr M 3.80 BS01 NUC F 1 S379 M452 A454 R456 T457 V458 S294 M365 A367 R369 T370 V371 A0A0J4U551 28579332 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGQTLQDYLMWQVELTPFTDTDRAIATSIVDAVDDTGYLTIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQSLDGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGMGNSARNDADGQFIRSNLQEARWLIKSLESRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSPRGIGGGGGGGGGGGGGGGGASSTAIRALVKKLIAAENPAKPLSDSKLTSMLSEQGIMVARRTVAKYRESLSIPPSNQR 5nsr M 3.80 BS02 NUC G 1 S379 S382 G405 L437 S438 D439 S440 K441 R456 S470 S294 S297 G319 L350 S351 D352 S353 K354 R369 S383 A0A0J4U551 28579332 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGQTLQDYLMWQVELTPFTDTDRAIATSIVDAVDDTGYLTIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQSLDGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGMGNSARNDADGQFIRSNLQEARWLIKSLESRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSPRGIGGGGGGGGGGGGGGGGASSTAIRALVKKLIAAENPAKPLSDSKLTSMLSEQGIMVARRTVAKYRESLSIPPSNQR 5nss M 5.80 BS01 NUC H 1 G12 G13 G16 A454 G5 G6 G9 A365 28579332 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGLQDYLMWQVELTPFTDTDRAIATSIVDAVDDTGYLTIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQSLDGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGMGNSARRSNLQEARWLIKSLESRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSPRGIGGGGGGGGGGGGGGGGASSTAIRALVKKLIAAENPAKPLSDSKLTSMLSEQGIMVARRTVAKYRESLSIPPSNQRKQLV 5nug A 3.80 BS01 ADP A 1 L1879 V1880 T1885 G1911 K1912 T1913 E1914 D1958 I2049 L2090 R2091 K2094 D2320 R2358 L430 V431 T436 G462 K463 T464 E465 D509 I592 L633 R634 K637 D850 R888 Q14204 28602352 AIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWTPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLETLHTTASNWLHLIPQTLSHLKRTENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQSVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE 5nug A 3.80 BS02 ATP A 1 L2191 T2192 W2203 S2226 G2227 G2229 K2230 S2231 M2232 E2344 L2369 M2373 N2377 R2684 R2726 R2729 L721 T722 W733 S756 G757 G759 K760 S761 M762 E874 L899 M903 N907 R1195 R1237 R1240 Q14204 28602352 AIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWTPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLETLHTTASNWLHLIPQTLSHLKRTENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQSVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE 5nug A 3.80 BS03 MG A 1 K2230 S2231 E2344 E2688 K760 S761 E874 E1199 Q14204 28602352 AIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWTPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLETLHTTASNWLHLIPQTLSHLKRTENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQSVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE 5nug A 3.80 BS04 ADP A 2 T2571 T2574 P2597 G2598 S2599 G2600 K2601 T2602 M2603 P2739 I2747 P2796 R2797 T2800 T1082 T1085 P1108 G1109 S1110 G1111 K1112 T1113 M1114 P1250 I1258 P1307 R1308 T1311 Q14204 28602352 AIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWTPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLETLHTTASNWLHLIPQTLSHLKRTENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQSVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE 5nug A 3.80 BS05 ADP A 3 V2907 L2909 V2910 S2939 G2940 A2941 G2942 K2943 T2944 T2945 W3097 R3174 L3177 V1418 L1420 V1421 S1450 G1451 A1452 G1453 K1454 T1455 T1456 W1608 R1685 L1688 Q14204 28602352 AIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWTPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLETLHTTASNWLHLIPQTLSHLKRTENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQSVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE 5o08 A 1.55 BS01 COD A 1 G8 S9 F10 G16 H17 V20 L36 N38 K41 L72 L73 K87 G88 R90 Y97 E98 M101 M104 N105 T118 Y122 G8 S9 F10 G16 H17 V20 L36 N38 K41 L72 L73 K87 G88 R90 Y97 E98 M101 M104 N105 T118 Y122 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLRGQA 5o08 A 1.55 BS02 COD B 1 L129 E132 L129 E132 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLRGQA 5o0a A 1.81 BS01 9FH A 1 T14 G16 H17 V20 R90 T118 Y122 V125 S126 S127 T14 G16 H17 V20 R90 T118 Y122 V125 S126 S127 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0b A 1.74 BS01 9FE A 1 G8 S9 F10 H17 V20 G88 G8 S9 F10 H17 V20 G88 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0b A 1.74 BS02 9FE A 2 G16 H17 V20 G88 R90 D94 S126 S127 G16 H17 V20 G88 R90 D94 S126 S127 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0b B 1.74 BS01 9FE B 1 C6 G8 S9 F10 H17 V20 G88 C6 G8 S9 F10 H17 V20 G88 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0b C 1.74 BS01 9FE C 1 C6 G8 S9 F10 H17 K87 G88 C6 G8 S9 F10 H17 K84 G85 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0c A 1.64 BS01 9F8 A 1 P7 G8 S9 F10 H17 V20 K87 G88 T118 P7 G8 S9 F10 H17 V20 K87 G88 T118 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0c B 1.64 BS01 9F8 B 1 P7 G8 S9 F10 H17 V20 G88 P7 G8 S9 F10 H17 V20 G86 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0c C 1.64 BS01 9F8 C 1 P7 G8 S9 H17 V20 K87 G88 T118 P7 G8 S9 H17 V20 K83 G84 T114 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLIAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0d B 1.54 BS01 9F5 B 1 P7 G8 S9 A34 L36 G69 G71 L73 P7 G8 S9 A34 L36 G69 G71 L73 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0f B 1.70 BS01 IOP B 1 G8 A34 L36 G69 Q70 G71 L73 K87 G8 A34 L36 G67 Q68 G69 L71 K85 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0f C 1.70 BS01 IOP C 1 P7 G8 A34 L36 G69 G71 L73 K87 P7 G8 A34 L36 G65 G67 L69 K83 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLIAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0h A 1.60 BS01 9FN B 1 E132 Y136 E132 Y136 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0h B 1.60 BS01 9FN B 1 P7 G8 A34 V35 L36 G69 G71 L73 P7 G8 A34 V35 L36 G69 G71 L73 2.7.7.3 B1MDL6 MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0h C 1.60 BS01 9FN C 1 A34 V35 L36 G69 Q70 G71 L72 L73 A35 V36 L37 G68 Q69 G70 L71 L72 2.7.7.3 B1MDL6 SMTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLR 5o0t A 2.05 BS01 HEM A 1 I269 L270 M273 I296 H299 K300 G303 Q304 F348 M351 W352 A355 Q356 R360 F365 F368 H372 Y375 W378 F379 I63 L64 M67 I90 H93 K94 G97 Q98 F142 M145 W146 A149 Q150 R154 F159 F162 H166 Y169 W172 F173 K9WT99 28607049 GSAYIKYYIENNWVKIAFLALYVFVNMFFFMSAVEKYESQGANLYVQIARGCGATLNLNGALILIPMLRHFMTWLRKTTINNYIPIDESIEFHKLVGQVMFALAIVHTGAHFLNYTTLPIPFAQSLFGTKAGISGFLLLLVFIIMWVTAQAPIRKGGKFALFYIAHMGYVLWFALALIHGPVFWQWVLLPVVGFIIELVIRWKAAE 5o0t A 2.05 BS02 HEM A 2 R256 G259 L262 N263 H313 T314 H317 F318 Y321 L332 A337 G341 F342 L344 L345 F348 W378 H385 P387 R50 G53 L56 N57 H107 T108 H111 F112 Y115 L126 A131 G135 F136 L138 L139 F142 W172 H179 P181 K9WT99 28607049 GSAYIKYYIENNWVKIAFLALYVFVNMFFFMSAVEKYESQGANLYVQIARGCGATLNLNGALILIPMLRHFMTWLRKTTINNYIPIDESIEFHKLVGQVMFALAIVHTGAHFLNYTTLPIPFAQSLFGTKAGISGFLLLLVFIIMWVTAQAPIRKGGKFALFYIAHMGYVLWFALALIHGPVFWQWVLLPVVGFIIELVIRWKAAE 5o0x A 2.20 BS01 FAD A 1 Y445 H459 P460 F461 T462 H476 R478 V480 G481 S482 W483 T484 I538 T541 W695 Y35 H49 P50 F51 T52 H66 R68 V70 G71 S72 W73 T74 I128 T131 W258 K9WT99 28607049 GSEPTFVVNASLLPSKVLGLQVQRPQSFNYQPGDYLFIKCPGISKFEWHPFTISSAPEMPDVLTLHIRAVGSWTGKLYQLIREQREEWIRSGSSQSLPGVPVYIDGPYGTPSTHIFESKYAILICAGIGVTPFASILKSILHRNQQNPAKMPLKKVHFYWLNREQKAFEWFVELLSKIEAEDTNNLFDLNLYLTLITGLKSRTKTGRPDWEEIFKDVAKQHAPDNVEVFFCGPTGLALQLRHLCTKYGFGYRKENFPWLEL 5o1o A 2.48 BS01 PRO A 1 D604 G635 T724 R726 D124 G155 T244 R246 1.5.1.8,1.5.1.9 Q9UDR5 RKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMESIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTLLRGTLRYKGYMKALNGFVKLGLINREALPNPLTWKQLLCDLVGISPSSEHDVLKEAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRDSFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFSKEIYGPILERIKAEGIIYTTQSTIK 5o1o B 2.48 BS01 PRO B 1 L603 D604 G634 G635 T724 R726 L123 D124 G154 G155 T244 R246 1.5.1.8,1.5.1.9 Q9UDR5 RKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMESIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTLLRGTLRYKGYMKALNGFVKLGLINREALPPLTWKQLLCDLVSSEHDVLKEAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRDSFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFSKEIYGPILERIKAEGIIYTTQSTIKP 5o21 A 2.06 BS01 CL A 1 K159 D294 G296 L297 K25 D160 G162 L163 2.7.11.1 Q9BYP7 MKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDRKLTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMRTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAE 5o26 A 2.38 BS01 ANP A 1 R155 G156 A157 F158 K159 V161 E228 M230 D275 K277 D279 N280 F282 D294 R21 G22 A23 F24 K25 V27 E87 M89 D134 K136 D138 N139 F141 D153 2.7.11.1 Q9BYP7 MKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESIKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMRTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRVE 5o26 A 2.38 BS02 MG A 1 N280 D294 N139 D153 2.7.11.1 Q9BYP7 MKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESIKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMRTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRVE 5o26 B 2.38 BS01 ANP B 1 G154 R155 G156 A157 F158 K159 V161 E228 L229 M230 D275 K277 D279 N280 F282 D294 G19 R20 G21 A22 F23 K24 V26 E82 L83 M84 D129 K131 D133 N134 F136 D148 2.7.11.1 Q9BYP7 KAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDEQQRFKEEAEMLKGLQHPNIVRFYDSWESKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMRTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRV 5o26 B 2.38 BS02 MG B 1 D279 N280 D294 D133 N134 D148 2.7.11.1 Q9BYP7 KAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDEQQRFKEEAEMLKGLQHPNIVRFYDSWESKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMRTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRV 5o2b A 2.04 BS01 9HE A 1 K159 V161 A174 C176 L225 T227 E228 L229 M230 F282 D294 L297 K29 V31 A44 C46 L88 T90 E91 L92 M93 F145 D157 L160 2.7.11.1 Q9BYP7 MEAEMKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQLTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESIKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRVE 5o2b B 2.04 BS01 9HE B 1 G154 R155 K159 V161 A174 C176 T227 E228 L229 M230 T234 F282 D294 G20 R21 K25 V27 A40 C42 T90 E91 L92 M93 T97 F145 D157 2.7.11.1 Q9BYP7 MKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLMTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFA 5o32 D 4.21 BS01 CA D 1 Y276 N279 E281 D283 D289 E290 Y251 N254 E256 D258 D264 E265 3.4.21.45 P05156 EDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATNRRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTFTKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGEETEILTADMDAERRRIKSLLPKLSCGVKNR 5o32 D 4.21 BS02 CA D 2 K239 A240 C241 D242 I244 D246 D252 E253 K214 A215 C216 D217 I219 D221 D227 E228 3.4.21.45 P05156 EDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATNRRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTFTKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGEETEILTADMDAERRRIKSLLPKLSCGVKNR 5t1e A 1.83 BS01 FAD A 1 V13 G14 G16 G17 T18 I19 D41 A42 S47 Q49 S50 A51 K57 I58 G184 S185 F186 A215 A216 G217 W219 L223 C343 C345 D370 G372 H373 S374 F375 K376 V13 G14 G16 G17 T18 I19 D41 A42 S47 Q49 S50 A51 K57 I58 G184 S185 F186 A215 A216 G217 W219 L223 C343 C345 D370 G372 H373 S374 F375 K376 Q0UIL6 28584265 MAPSRANTSVIVVGGGGTIGSSTALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLNKIMGVSLRNPVDLQLALEARQMWNEDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLSRDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVETVDGTRYYADKVVLAAGAWSPTLVELHEQCVSKAWVYGHIQLTPEEAARYKNSPVVYNGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDASDVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKLLPNIGKHVVELLEGTLADDLAHAWRWRPGSGDALKSRRSAPAKDLADMPGWNHD 5t4a A 2.10 BS01 GLC A 1 R463 D530 W615 R437 D504 W589 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4a A 2.10 BS02 BGC A 1 H458 N465 D466 A529 D530 F535 N540 W615 H432 N439 D440 A503 D504 F509 N514 W589 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4a A 2.10 BS03 BGC A 2 Y387 H458 D466 F469 H470 E542 S543 E546 W615 I626 Y361 H432 D440 F443 H444 E516 S517 E520 W589 I600 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4a A 2.10 BS04 BGC A 3 Y387 K391 H458 W616 W664 R704 Y361 K365 H432 W590 W638 R678 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4a A 2.10 BS05 BGC A 4 W616 E699 R704 W590 E673 R678 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4c A 1.80 BS02 BGC A 2 H458 N465 D466 A529 D530 N540 W615 H432 N439 D440 A503 D504 N514 W589 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4c A 1.80 BS03 BGC A 3 Y387 H458 D466 F469 H470 Q542 E546 W615 I626 Y361 H432 D440 F443 H444 Q516 E520 W589 I600 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4c A 1.80 BS04 BGC A 4 Y387 K391 H458 W616 I626 W664 R704 Y361 K365 H432 W590 I600 W638 R678 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4c A 1.80 BS06 BGC A 6 M91 F535 D536 M65 F509 D510 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4c A 1.80 BS07 BGC A 7 F535 D536 A537 W606 K609 F509 D510 A511 W580 K583 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4c A 1.80 BS08 BGC A 8 I604 W606 K609 D611 T614 W615 I578 W580 K583 D585 T588 W589 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4c A 1.80 BS09 BGC A 9 T614 W615 W616 N617 T588 W589 W590 N591 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4g A 1.80 BS01 GLC A 1 Y387 H458 D466 F469 H470 E542 E546 W615 I626 Y361 H432 D440 F443 H444 E516 E520 W589 I600 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4g A 1.80 BS02 BGC A 1 Y387 K391 H458 W616 I626 L629 W664 R704 Y361 K365 H432 W590 I600 L603 W638 R678 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4g A 1.80 BS04 BGC A 3 R463 D530 F535 W615 R437 D504 F509 W589 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4g A 1.80 BS07 BGC A 6 F535 D536 A537 W606 K609 W615 F509 D510 A511 W580 K583 W589 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4g A 1.80 BS08 BGC A 7 I604 W606 D611 T614 W615 I578 W580 D585 T588 W589 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4g A 1.80 BS09 BGC A 8 T614 W615 N617 T588 W589 N591 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4g A 1.80 BS10 BGC A 9 D51 G53 D25 G27 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4g A 1.80 BS11 BGC A 10 D51 G53 F54 Q57 D25 G27 F28 Q31 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t4g A 1.80 BS12 BGC A 11 F54 G383 S384 D385 F28 G357 S358 D359 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5t8x B 1.69 BS01 NAP B 1 G16 G18 N19 F20 S39 R40 S41 Y43 C72 T73 S74 S77 E80 V81 V99 L100 S101 H124 P125 F127 G128 P129 S223 L226 G9 G11 N12 F13 S32 R33 S34 Y36 C65 T66 S67 S70 E73 V74 V92 L93 S94 H117 P118 F120 G121 P122 S216 L219 1.3.1.13 I1MYY4 QSLKIGIVGFGNFGQFLAKTMIKQGHTLTATSRSDYSELCLQMGIHFFRDVSAFLTADIDVIVLCTSILSLSEVVGSMPLTSLKRPTLFVDVLSVKEHPRELLLRELPEDSDILCTHPMFGPQTAKNGWTDHTFMYDKVRIRDEVICSNFIQIFATEGCKMVQMSCEEHDRAAAKSQFITHTIGRTLGEMDIQSTPIDTKGFETLVKLKETMMRNSFDLYSGLFVYNRFARQELENLEHALHKVKETLMIQRT 5t95 A 1.69 BS01 NAP A 1 G16 F17 G18 N19 F20 S39 R40 S41 Y43 C72 T73 S74 S77 E80 V81 V99 L100 S101 P125 F127 G128 P129 D222 S223 L226 G8 F9 G10 N11 F12 S31 R32 S33 Y35 C64 T65 S66 S69 E72 V73 V91 L92 S93 P117 F119 G120 P121 D214 S215 L218 1.3.1.13 I1MYY4 SLKIGIVGFGNFGQFLAKTMIKQGHTLTATSRSDYSELCLQMGIHFFRDVSAFLTADIDVIVLCTSILSLSEVVGSMPLTSLKRPTLFVDVLSVKEHPRELLLRELPEDSDILCTHPMFGPQTAKNGWTDHTFMYDKVRIRDEVICSNFIQIFATEGCKMVQMSCEEHDRAAAKSQFITHTIGRTLGEMDIQSTPIDTKGFETLVKLKETTMRDSFDLYSGLFVYNRFARQELENLEHALHKVKETLMI 5t95 A 1.69 BS02 TYR A 1 S101 H124 G128 P129 Q130 T131 Q184 D222 S93 H116 G120 P121 Q122 T123 Q176 D214 1.3.1.13 I1MYY4 SLKIGIVGFGNFGQFLAKTMIKQGHTLTATSRSDYSELCLQMGIHFFRDVSAFLTADIDVIVLCTSILSLSEVVGSMPLTSLKRPTLFVDVLSVKEHPRELLLRELPEDSDILCTHPMFGPQTAKNGWTDHTFMYDKVRIRDEVICSNFIQIFATEGCKMVQMSCEEHDRAAAKSQFITHTIGRTLGEMDIQSTPIDTKGFETLVKLKETTMRDSFDLYSGLFVYNRFARQELENLEHALHKVKETLMI 5t95 B 1.69 BS02 TYR B 1 S101 H124 G128 P129 Q130 T131 Q184 H188 D222 S94 H117 G121 P122 Q123 T124 Q177 H181 D215 1.3.1.13 I1MYY4 QSLKIGIVGFGNFGQFLAKTMIKQGHTLTATSRSDYSELCLQMGIHFFRDVSAFLTADIDVIVLCTSILSLSEVVGSMPLTSLKRPTLFVDVLSVKEHPRELLLRELPEDSDILCTHPMFGPQTAKNGWTDHTFMYDKVRIRDEVICSNFIQIFATEGCKMVQMSCEEHDRAAAKSQFITHTIGRTLGEMDIQSTPIDTKGFETLVKLKETTMRDSFDLYSGLFVYNRFARQELENLEHALHKVKETLMI 5t9f A 1.99 BS02 TYR A 1 S101 H124 F127 G128 P129 Q130 T131 Q184 H188 D222 S93 H116 F119 G120 P121 Q122 T123 Q176 H180 D214 1.3.1.13 I1MYY4 SLKIGIVGFGNFGQFLAKTMIKQGHTLTATSRSDYSELCLQMGIHFFRDVSAFLTADIDVIVLCTSILSLSEVVGSMPLTSLKRPTLFVDVLSVKEHPRELLLRELPEDSDILCTHPMFGPQTAKNGWTDHTFMYDKVRIRDEVICSNFIQIFATEGCKMVQMSCEEHDRAAAKSQFITHTIGRTLGEMDIQSTPIDTKGFETLVKLKETMMRDSFDLYSGLFVYNRFARQELENLEHALHKVKETLMI 5t9f B 1.99 BS01 NAP B 1 G16 G18 N19 F20 S39 R40 S41 Y43 C72 T73 S74 I75 S77 E80 V81 V99 L100 S101 H124 P125 F127 G128 P129 D222 S223 G9 G11 N12 F13 S32 R33 S34 Y36 C65 T66 S67 I68 S70 E73 V74 V92 L93 S94 H117 P118 F120 G121 P122 D215 S216 1.3.1.13 I1MYY4 QSLKIGIVGFGNFGQFLAKTMIKQGHTLTATSRSDYSELCLQMGIHFFRDVSAFLTADIDVIVLCTSILSLSEVVGSMPLTSLKRPTLFVDVLSVKEHPRELLLRELPEDSDILCTHPMFGPQTAKNGWTDHTFMYDKVRIRDEVICSNFIQIFATEGCKMVQMSCEEHDRAAAKSQFITHTIGRTLGEMDIQSTPIDTKGFETLVKLKETMMRDSFDLYSGLFVYNRFARQELENLEHALHKVKETLMIQRT 5tgi A 1.98 BS01 III C 1 I35 P36 D37 A38 L39 S40 M106 K125 E129 Y132 L133 F136 K137 E144 I6 P7 D8 A9 L10 S11 M77 K96 E100 Y103 L104 F107 K108 E115 Q9Y5X3 SLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYD 5toa A 2.50 BS01 EST A 1 L298 L301 E305 M336 L339 M340 F356 I373 I376 G472 H475 L476 L36 L39 E43 M74 L77 M78 F94 I111 I114 G201 H204 L205 Q92731 28615710 ALSPEQLVLTLLEAEPPHVLISRPAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYDSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLR 5toa B 2.50 BS01 EST B 1 M295 L298 L301 E305 M336 L339 M340 L343 F356 I373 I376 G472 H475 L476 M35 L38 L41 E45 M76 L79 M80 L83 F96 I113 I116 G203 H206 L207 Q92731 28615710 MALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLR 5tuq A 2.71 BS01 J63 A 1 L100 K101 K102 K103 V106 V179 Y188 P225 F227 W229 L234 H235 P236 Y318 L101 K102 K103 K104 V107 V180 Y189 P226 F228 W230 L235 H236 P237 Y319 3.4.23.16,2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 28182989 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 5tw6 A 1.70 BS01 CAZ A 1 C69 S70 N104 Y105 S130 N132 N170 T171 K234 T235 G236 S237 G238 D240 R276 C42 S43 N77 Y78 S103 N105 N143 T144 K207 T208 G209 S210 G211 D212 R247 3.5.2.6 Q9L5C7 28613873 SAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTASTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAE 5twe A 1.50 BS01 CAZ A 1 C69 G70 N104 Y105 S130 N132 S167 N170 T171 K234 T235 G236 S237 G238 D240 C43 G44 N78 Y79 S104 N106 S141 N144 T145 K208 T209 G210 S211 G212 D213 3.5.2.6 Q9L5C7 28613873 TSAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCGTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAEGL 5u2n A 1.73 BS01 7TA A 1 Y188 H191 F193 R196 D219 V242 A244 S275 P307 I309 R311 R349 I351 A379 Y168 H171 F173 R176 D199 V222 A224 S255 P287 I289 R291 R329 I331 A359 2.4.2.12 P43490 28468779 FNILLATDSYKVTHYKQYPPNTSKVYSYFECREYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIE 5u53 A 1.40 BS01 CAZ A 1 C69 S70 N104 Y105 S130 N132 P167 N170 T235 G236 S237 G238 D240 C42 S43 N77 Y78 S103 N105 P140 N143 T208 G209 S210 G211 D212 3.5.2.6 H6UQI0 28613873 SAVQQKLAALEKSSTGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTAPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAEGL 5u7d A 1.75 BS01 19F A 1 Y655 H656 T768 L770 H773 T805 L809 Q812 I826 Y827 F830 M847 L858 Q859 S861 F862 I866 I870 Y77 H78 T190 L192 H195 T227 L231 Q234 I248 Y249 F252 M269 L280 Q281 S283 F284 I288 I292 3.1.4.17 O00408 28574706 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5u7i A 2.00 BS01 7XS A 1 Y655 H656 L774 D808 L809 Q812 I822 I826 F830 M847 Q859 F862 I866 Y77 H78 L196 D230 L231 Q234 I244 I248 F252 M269 Q281 F284 I288 3.1.4.17 O00408 28574706 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5u7i D 2.00 BS01 7XS D 1 Y655 H656 L770 L774 D808 L809 Q812 I826 Y827 F830 M847 Q859 F862 Y66 H67 L181 L185 D219 L220 Q223 I237 Y238 F241 M258 Q270 F273 3.1.4.17 O00408 28574706 IQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSL 5u7j A 1.90 BS01 7XV A 1 Y655 H656 L770 L809 Q812 I826 F830 M847 Q859 F862 I866 Y77 H78 L192 L231 Q234 I248 F252 M269 Q281 F284 I288 3.1.4.17 O00408 28574706 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5u7j D 1.90 BS01 7XV D 1 H656 L770 L774 L809 Q812 I826 F830 M847 Q859 F862 I866 H67 L181 L185 L220 Q223 I237 F241 M258 Q270 F273 I277 3.1.4.17 O00408 28574706 IQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5u7k A 2.06 BS02 7Y1 A 1 L770 H773 T805 D808 L809 I826 F830 M847 Q859 F862 L194 H197 T229 D232 L233 I250 F254 M271 Q283 F286 3.1.4.17 O00408 28574706 AMDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5u7l A 2.38 BS01 7Y4 A 1 Y655 L770 T805 D808 L809 Q812 I826 F830 M847 Q859 F862 Y77 L192 T227 D230 L231 Q234 I248 F252 M269 Q281 F284 3.1.4.17 O00408 28574706 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLD 5u7l A 2.38 BS03 MG A 1 H696 D697 H118 D119 3.1.4.17 O00408 28574706 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLD 5u7l B 2.38 BS01 7Y4 B 1 Y655 T805 D808 L809 Q812 I826 M847 Q859 F862 I870 Y66 T198 D201 L202 Q205 I219 M240 Q252 F255 I263 3.1.4.17 O00408 28574706 IQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLD 5u7l C 2.38 BS01 7Y4 C 1 Y655 H656 L770 T805 L809 Q812 I826 M847 Q859 F862 Y77 H78 L192 T227 L231 Q234 I248 M269 Q281 F284 3.1.4.17 O00408 28574706 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 5ues A 1.62 BS01 87S A 1 W374 P375 F376 V380 N433 H437 E438 V439 M442 W26 P27 F28 V32 N85 H89 E90 V91 M94 O60885 SHMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKM 5uf0 A 1.35 BS01 89J A 1 F376 V380 L387 C429 N433 F27 V31 L38 C80 N84 O60885 28368119 HMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKM 5uhv A 1.67 BS01 GNP A 1 G12 G13 V14 G15 K16 S17 A18 F28 D30 E31 P34 T35 G60 N116 K117 D119 L120 S145 A146 K147 G12 G13 V14 G15 K16 S17 A18 F28 D30 E31 P34 T35 G60 N116 K117 D119 L120 S145 A146 K147 P01111 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQY 5uj6 A 1.90 BS01 CA A 1 D176 D341 D367 D145 D310 D336 A0A078SUX9 28578872 QRQTQTINDSWKFLKGECTAAADSAFDDSKWTSIHLPHTWNTDAYTEKDYYRGTGWYRRQLTLPQGWKEKQIILRLDAAGKSATIYINGKNVGEHAGGYTACSFNITPFLSFDTPNTLAVCVDNARQDIAPISGDFTFFGGIYRDVWLTAVPNQHFNLTNHGSDGLFISTPQVSEEQATLSIRGEVKNDAPEKATLELTHTIYRPDGTLLQTLKKNIQLKAGETYAFSNEATPVLKPELWTPETPRLYRVETTLRNRKTKTLLDQSNHYTAFRWFRFDGDEGFFLNGKPYKLRGICRHQDQKPIGPALTDEMHRRDFLLMKEMGANFIRISHYPQDDALLEMCDKLGMLAWEEIPIIDIVPNTPGYGDNCERNLREMIRQHYNHPSIITWGYMNEILLVTQRKYKTEAELKPVLERTLALANRLERVLKEEDSTRISTMAFHGSNSYNETGLSKITDIVGWNLYQGWYGGDLTGFEKFLAQQHQNHPTHPMIVSEYGAGSDKRLHSLHPRAFDFSIEYQQKYLEHYLPVLEDTPYICGGTHWNFIDFSSALRDESMPRINNKGLVYADRTPKDVYHYYQAAWRKDIPVLHIASRDWTDRAGVQQGNAPVYLPVKIYTNLSEVELFIDGISLGKQKTENYTATFEVPFSNRNPFLFAQGNYQGKTVQDGLRINFTPIPACLDANNLKGLELAVNVGSQCFFTSDESQLTWLPDQPYAAGSWGYIGGKEGTAQTEIQNTADGPLFQTLRNEIEGYRFDAPQGVYEIELLFTDIFRRESTFGISINGEVVEESLSPCKESGYFRALRKKYYITNDKEYIDIRFHSTSGTCFLNGIKLRNIY 5um9 A 2.81 BS01 NUC D 1 Q41 F42 I44 A45 V46 M65 Y69 R70 R73 R103 R129 T195 S197 K201 G240 I241 G242 P243 K244 R245 Q40 F41 I43 A44 V45 M64 Y68 R69 R72 R102 R128 T194 S196 K200 G239 I240 G241 P242 K243 R244 3.1.-.- P39748 GIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFNGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTLEVLFQ 5um9 A 2.81 BS02 NUC E 1 G2 A7 K8 M37 Y40 N86 G87 K93 R100 R103 K135 N138 E160 E178 D179 R192 R245 Y268 G1 A6 K7 M36 Y39 N85 G86 K92 R99 R102 K134 N137 E159 E177 D178 R191 R244 Y267 3.1.-.- P39748 GIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFNGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTLEVLFQ 5upf A 1.69 BS01 8HV A 1 Y188 K189 H191 F193 R196 D219 V242 A244 S275 I309 R311 R349 I351 A379 Y168 K169 H171 F173 R176 D199 V222 A224 S255 I289 R291 R329 I331 A359 2.4.2.12 P43490 28610984 FNILLATDSYKVTHYKQYPPNTSKVYSYFECREYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNI 5upm A 1.70 BS03 GLC A 1 Y387 H458 D466 F469 H470 Q542 S543 E546 W615 I626 Y361 H432 D440 F443 H444 Q516 S517 E520 W589 I600 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNGD 5upm A 1.70 BS07 BGC A 6 I604 W606 K609 D611 A613 T614 W615 I578 W580 K583 D585 A587 T588 W589 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNGD 5upn A 1.80 BS03 BGC A 3 Y387 H458 D466 F469 H470 Q542 E546 W615 Y360 H431 D439 F442 H443 Q515 E519 W588 Q9KG76 HAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNGD 5upo A 1.70 BS01 BGC A 1 R463 N465 D530 W615 R437 N439 D504 W589 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQQSSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5uxa A 1.95 BS01 CA A 1 A143 L145 A142 L144 O32553 SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEVQGS 5v1w A 2.15 BS02 BGC A 2 R463 D530 F535 R437 D504 F509 Q9KG76 MHAVSVGKGSYATEFPEIDFGGINDPGFRDQQGEPPATIYRSDRVTGPMQTNSWWGSLAVDRFSMNQYPHPFSVRHRAEGLHVFYDAPHNMVVHENREAGTWHIHGAIGTDFTIKHSGTANFEQAVVDDYNDWYVRGLLENGAHQMAITYGVGSPYIFVEYEDGSAVLDFDIAPDVWEMNGHVIGFSTHDHKHYAAFAPPGQNWSGIGSKTLTNNADYIAIAKLPEKDGNMLAKFEQYAYSVVRDAVADWTYDEATGTVTTTFEVTTEAKVQGAPDGTIFALYPHQYRHLASSSENQLLQNYQYEIIRGTMIGLEGKRFTTELTYPGVLPSLPDLGDYDRERLIGYLHDATSDYPTGSDTYELGKYIGKLATLAPIADQMGEYELAEQFRGELKDILEDWLQATNASGQLKGKNLFYYNENWGTILGYHAAHSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYLRMFDPYSGNSWADGLATFDAGNNQESSSEAMHAWTNVILWAEATGNKALRDRAIYLYTTEMSAINEYFFDVHQEIFPEEYGPEIVTINWGGKMDHATWWNSGKVEKYAINWLPFHGGSLYLGHHPDYVDRAYEELRRDIGSTDWNLWSNLVWMYRAFTNPDDALQQMEASIDDYGLFDPGNEKIIERGSTKAQTYHWIHNLAELGRVDPTVTANHPIYAVFNKNGNRTYIVYNFSDSPITVQFSDGHSIQVEPHSFNIGNG 5v6s A 1.70 BS02 8YD A 1 G10 C12 K16 P34 T58 A59 G60 Q61 E62 E63 Y64 R68 D69 M72 H95 Y96 Q99 I100 V103 G11 C13 K17 P35 T59 A60 G61 Q62 E63 E64 Y65 R69 D70 M73 H96 Y97 Q100 I101 V104 P01116 28621541 GMTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK 5v6v A 1.72 BS02 8YA A 1 C12 T58 A59 G60 Y64 R68 D69 M72 H95 Y96 Q99 I100 V103 C11 T57 A58 G59 Y63 R67 D68 M71 H94 Y95 Q98 I99 V102 P01116 28621541 TEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHK 5v6v B 1.72 BS02 CA B 1 E3 Y4 E76 E2 Y3 E75 P01116 28621541 TEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKE 5v6v B 1.72 BS03 8YA B 1 G10 C12 A59 G60 Q61 E62 Y64 R68 D69 M72 Y96 Q99 I100 V103 G9 C11 A58 G59 Q60 E61 Y63 R67 D68 M71 Y95 Q98 I99 V102 P01116 28621541 TEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKE 5val A 2.26 BS01 92D A 1 I463 V471 A481 V482 K483 E501 V504 L505 L514 I527 T529 Q530 W531 C532 H574 G593 D594 F595 I18 V26 A36 V37 K38 E56 V59 L60 L69 I82 T84 Q85 W86 C87 H129 G148 D149 F150 2.7.11.1 P15056 28557458 SSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGSILWMAPEVIRMKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARS 5val B 2.26 BS01 92D B 1 V471 A481 V482 K483 E501 L505 L514 I527 T529 Q530 W531 C532 H574 F583 G593 D594 F595 V24 A34 V35 K36 E54 L58 L67 I80 T82 Q83 W84 C85 H127 F136 G146 D147 F148 2.7.11.1 P15056 28557458 DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLGSILWMAPEVIRMNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 5vam A 2.10 BS01 92J A 1 I463 V471 A481 K483 E501 L505 I513 L514 I527 T529 Q530 W531 C532 H574 F583 G593 D594 F595 W604 I15 V23 A33 K35 E53 L57 I65 L66 I79 T81 Q82 W83 C84 H126 F135 G145 D146 F147 W156 2.7.11.1 P15056 28557458 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 5vam B 2.10 BS01 92J B 1 I463 V471 A481 K483 E501 V504 L505 L514 I527 T529 W531 C532 F583 G593 D594 F595 W604 I15 V23 A33 K35 E53 V56 L57 L66 I79 T81 W83 C84 F135 G145 D146 F147 W152 2.7.11.1 P15056 28557458 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLARWSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 5vc8 A 1.80 BS01 NUC W 1 K304 A305 K84 A85 2.1.1.43 O96028 HLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFT 5vc9 C 2.10 BS01 NUC A 1 R136 H164 Q165 I166 R170 K171 R3 H31 Q32 I33 R37 K38 Q9H2H0 KKRKRCGVCVPCKRLINCGVCSSCRNRKTGHQICKFRKCEELKKKP 5vc9 C 2.10 BS02 NUC B 1 T162 G163 H164 Q165 T29 G30 H31 Q32 Q9H2H0 KKRKRCGVCVPCKRLINCGVCSSCRNRKTGHQICKFRKCEELKKKP 5vc9 C 2.10 BS03 ZN C 1 C139 C142 C145 C172 C6 C9 C12 C39 Q9H2H0 KKRKRCGVCVPCKRLINCGVCSSCRNRKTGHQICKFRKCEELKKKP 5vc9 F 2.10 BS01 NUC D 1 R136 H164 Q165 I166 R170 K171 L175 R3 H31 Q32 I33 R37 K38 L42 Q9H2H0 KKRKRCGVCVPCKRLINCGVCSSCRNRKTGHQICKFRKCEELKK 5vfc A 1.64 BS01 9BA A 1 A47 V48 S49 A65 G89 I90 S91 D92 D107 Y131 F133 C134 F149 S175 K259 Y260 C261 F263 I305 L321 A17 V18 S19 A35 G59 I60 S61 D62 D77 Y101 F103 C104 F119 S145 K229 Y230 C231 F233 I275 L291 P61964 28603984 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 5vtq A 2.95 BS01 SIA A 1 Y98 G134 G135 S136 N137 W153 T155 E190 L194 S228 Y90 G126 G127 S128 N129 W145 T147 E182 L186 S220 Q91MA7 28618270 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRLSSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTR 5vtq E 2.95 BS02 GAL E 1 W222 L225 W214 L217 Q91MA7 28618270 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRLSSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPE 5vtr A 2.50 BS01 SIA A 1 Y98 G134 G135 S136 N137 W153 H183 E190 L194 S228 Y90 G126 G127 S128 N129 W145 H175 E182 L186 S220 Q91MA7 28618270 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRLSSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTR 5vtr E 2.50 BS01 SIA E 1 Y98 G134 G135 S136 N137 W153 E190 L194 S228 Y90 G126 G127 S128 N129 W145 E182 L186 S220 Q91MA7 28618270 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRLSSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPE 5vtv A 2.25 BS01 SIA A 1 Y98 G134 G135 S136 N137 W153 H183 E190 L194 A228 Y90 G126 G127 S128 N129 W145 H175 E182 L186 A220 Q91MA7 28618270 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRMTSARISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTR 5vtv C 2.25 BS02 GAL C 1 W222 M225 W214 M217 Q91MA7 28618270 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRMTSARISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPE 5vtw A 2.35 BS01 SIA A 1 Y98 G134 G135 S136 N137 H183 E190 A228 Y90 G126 G127 S128 N129 H175 E182 A220 Q91MA7 28618270 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRMTSARISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTR 5vty E 2.36 BS01 SIA E 1 Y98 G134 G135 S136 N137 W153 E190 L194 Y90 G126 G127 S128 N129 W145 E182 L186 Q91MA7 28618270 PGATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRQASSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTR 5vw1 A 2.60 BS01 NUC C 1 K33 L35 G56 E57 T58 A59 T62 R63 K65 R66 R69 R70 R71 Y72 R74 R75 K76 N77 R78 Y81 L101 S104 F105 L106 V107 K111 R115 H116 I122 V123 E125 V126 H129 P133 T134 I135 H160 K163 F164 R165 G166 F168 Y325 H328 H329 K336 R340 F351 F352 Y359 A360 I363 D364 G366 K401 Q402 R403 T404 F405 N407 G408 F446 R447 I448 Y450 G453 P454 L455 A456 R457 N459 S460 F462 W464 R467 T472 I473 P475 F491 M495 N497 R661 S730 P731 K734 K735 L738 Q739 K742 K749 V750 G752 R753 K1097 E1099 V1100 T1102 G1103 G1104 F1105 I1110 P1112 K1113 R1122 K1123 K1124 W1126 K1130 Y1131 M1169 H1349 Q1350 S1351 Y1356 E1357 K34 L36 G57 E58 T59 A60 T63 R64 K66 R67 R70 R71 R72 Y73 R75 R76 K77 N78 R79 Y82 L102 S105 F106 L107 V108 K112 R116 H117 I123 V124 E126 V127 H130 P134 T135 I136 H161 K164 F165 R166 G167 F169 Y326 H329 H330 K337 R341 F352 F353 Y360 A361 I364 D365 G367 K402 Q403 R404 T405 F406 N408 G409 F447 R448 I449 Y451 G454 P455 L456 A457 R458 N460 S461 F463 W465 R468 T473 I474 P476 F492 M496 N498 R662 S728 P729 K732 K733 L736 Q737 K740 K747 V748 G750 R751 K1091 E1093 V1094 T1096 G1097 G1098 F1099 I1104 P1106 K1107 R1116 K1117 K1118 W1120 K1124 Y1125 M1163 H1343 Q1344 S1345 Y1350 E1351 3.1.-.- Q99ZW2 28602637 SMDKKYSIGLAIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDAIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEITAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLGGD 5vyj B 3.30 BS01 GLY A 1 S100 F225 R226 T227 E229 L938 S65 F175 R176 T177 E179 L885 4.1.1.31 Q84KR7 EYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKSDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 5vyj D 3.30 BS01 GLY C 1 F225 T227 D228 E229 F176 T178 D179 E180 4.1.1.31 Q84KR7 EYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKLSDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 5w0b A 2.61 BS01 ZN A 1 C1347 C1350 H1355 C1360 C320 C323 H328 C333 2.7.7.52 Q5VYS8 QLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLAVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEICGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPGFPKDYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCP 5w0m A 2.30 BS01 NUC H 1 F1045 G1046 A1060 I1099 A1102 K1103 V1104 I1106 N1124 A1127 N1130 T1131 A1163 S1164 Y1171 H1286 L1288 A1290 G1291 R1345 I1353 G1354 H1355 F59 G60 A74 I113 A116 K117 V118 I120 N138 A141 N144 T145 A177 S178 Y185 H295 L297 A299 G300 R354 I362 G363 H364 2.7.7.52 Q5VYS8 LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLAVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMR 5w0m A 2.30 BS02 ZN A 1 C1347 C1350 H1355 C1360 C356 C359 H364 C369 2.7.7.52 Q5VYS8 LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLAVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMR 5w0m B 2.30 BS01 NUC I 1 F1045 G1046 A1060 I1099 T1101 A1102 K1103 V1104 I1106 N1124 A1127 N1130 T1131 A1163 S1164 Y1171 H1286 L1288 A1290 G1291 R1345 F58 G59 A73 I112 T114 A115 K116 V117 I119 N137 A140 N143 T144 A176 S177 Y184 H297 L299 A301 G302 R348 2.7.7.52 Q5VYS8 EPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLAVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVSKMEYFFDPDVLTEGELAPNDRCC 5w0m C 2.30 BS01 NUC J 1 F1045 G1046 A1060 I1099 T1101 A1102 K1103 V1104 I1106 D1119 N1124 A1127 N1130 T1131 A1163 S1164 Y1171 K1274 H1286 L1288 A1290 G1291 R1345 I1353 G1354 H1355 F58 G59 A73 I112 T114 A115 K116 V117 I119 D132 N137 A140 N143 T144 A176 S177 Y184 K287 H299 L301 A303 G304 R354 I362 G363 H364 2.7.7.52 Q5VYS8 EPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLAVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPPKDYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPM 5w0n A 2.50 BS01 MG A 1 D1058 D1060 D74 D76 2.7.7.52 Q5VYS8 IQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMR 5w0n A 2.50 BS02 2KH A 1 F1045 G1046 S1047 S1057 D1058 D1060 A1127 N1130 K1152 S1169 S1170 Y1171 H1286 L1288 F61 G62 S63 S73 D74 D76 A143 N146 K168 S185 S186 Y187 H302 L304 2.7.7.52 Q5VYS8 IQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMR 5w0n A 2.50 BS03 UPU A 1 F1045 D1058 D1060 I1099 A1102 V1104 I1106 D1119 N1124 A1163 S1164 K1352 I1353 G1354 H1355 F61 D74 D76 I115 A118 V120 I122 D135 N140 A179 S180 K368 I369 G370 H371 2.7.7.52 Q5VYS8 IQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMR 5w0n B 2.50 BS01 MG B 1 S1047 D1058 D1060 S61 D72 D74 2.7.7.52 Q5VYS8 LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPM 5w0n C 2.50 BS03 UPU C 1 F1045 D1058 D1060 I1099 T1101 A1102 V1104 I1106 D1119 N1124 A1163 S1164 F59 D72 D74 I113 T115 A116 V118 I120 D133 N138 A177 S178 2.7.7.52 Q5VYS8 LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVSKMEYFFDPDVLTEGELAPND 5w0o A 2.49 BS01 NUC C 1 I1099 T1101 A1102 K1103 V1104 D1119 N1124 A1163 S1164 I109 T111 A112 K113 V114 D129 N134 A173 S174 2.7.7.52 Q5VYS8 LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLT 5w0o A 2.49 BS02 NUC D 1 L1097 I1099 S1164 R1165 L107 I109 S174 R175 2.7.7.52 Q5VYS8 LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLT 5w0o A 2.49 BS03 UTP A 1 F1045 G1046 S1047 N1050 N1130 K1152 S1169 S1170 Y1171 T1174 H1286 L1288 F59 G60 S61 N64 N140 K162 S179 S180 Y181 T184 H288 L290 2.7.7.52 Q5VYS8 LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLT 5w0o B 2.49 BS01 NUC C 1 L1097 I1099 S1164 R1165 S1293 L102 I104 S169 R170 S293 2.7.7.52 Q5VYS8 PLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFEYFFDP 5w0o B 2.49 BS02 NUC D 1 I1099 T1101 A1102 K1103 V1104 I1106 D1119 N1124 A1163 S1164 A1290 G1291 I104 T106 A107 K108 V109 I111 D124 N129 A168 S169 A290 G291 2.7.7.52 Q5VYS8 PLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFEYFFDP 5w0o B 2.49 BS03 UTP B 1 F1045 G1046 S1047 S1057 D1058 N1130 S1170 Y1171 H1286 F54 G55 S56 S66 D67 N135 S175 Y176 H286 2.7.7.52 Q5VYS8 PLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFEYFFDP 5w10 A 2.15 BS01 CMP A 1 N46 W47 S48 E65 I67 G82 I83 A84 F105 S106 V109 F115 T117 I120 E136 V138 N44 W45 S46 E63 I65 G80 I81 A82 F103 S104 V107 F113 T115 I118 E134 V136 Q72MQ6 28601495 LKDSKPELIKLYSSLGKIITSSLEQQEVLSAVMEEVRLFFSPKNWSLMRYDENSEELFFLIAEGIQFNHIRSIRLKSGEGIAGSVVQTKSPIFVENVKNDPRFSKKVDEKTGFETKTIIAVPMIFRGEVHGVIELVNRFDGSSFSPEDLVILQTIADFTAISLAHSDQYEKTK 5w10 B 2.15 BS01 CMP B 1 N46 W47 S48 F61 E65 I67 L77 G82 I83 A84 F105 S106 V109 F115 T117 I120 E136 V138 N43 W44 S45 F58 E62 I64 L74 G79 I80 A81 F102 S103 V106 F112 T114 I117 E133 V135 Q72MQ6 28601495 KDSKPELIKLYSSLGKIITSSLEQQEVLSAVMEEVRLFFSPKNWSLMRYDENSEELFFLIAEGIQFNHIRSIRLKSGEGIAGSVVQTKSPIFVENVKNDPRFSKKVDEKTGFETKTIIAVPMIFRGEVHGVIELVNRFDGSSFSPEDLVILQTIADFTAISLAHSDQYEKTK 5w49 A 2.40 BS01 NAD A 1 D190 N191 C195 G220 G222 D223 V224 T242 E243 I244 D245 N248 T275 T276 G277 C278 I281 I299 G300 L344 N346 D187 N188 C192 G217 G219 D220 V221 T239 E240 I241 D242 N245 T272 T273 G274 C275 I278 I296 G297 L341 N343 3.3.1.1 P23526 28533090 KLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 5w49 A 2.40 BS02 9W1 A 1 H55 T57 E59 S83 Q85 L347 A350 M351 H353 M358 F362 H52 T54 E56 S80 Q82 L344 A347 M348 H350 M355 F359 3.3.1.1 P23526 28533090 KLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 5w4b A 2.65 BS02 9W4 A 1 H55 T57 E59 N80 S83 Q324 R343 L347 H353 M358 H51 T53 E55 N76 S79 Q320 R339 L343 H349 M354 3.3.1.1 P23526 28533090 LPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 5w4b B 2.65 BS03 9W4 B 1 H55 T57 E59 N80 F82 S83 R343 L347 H353 M358 H52 T54 E56 N77 F79 S80 R340 L344 H350 M355 3.3.1.1 P23526 28533090 KLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 5w4b C 2.65 BS02 9W4 C 1 H55 T57 E59 N80 S83 R343 L347 H353 M358 H51 T53 E55 N76 S79 R339 L343 H349 M354 3.3.1.1 P23526 28533090 LPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 5w4b F 2.65 BS03 9W4 F 1 H55 T57 E59 F82 S83 Q324 R343 L347 M351 H353 M358 H51 T53 E55 F78 S79 Q320 R339 L343 M347 H349 M354 3.3.1.1 P23526 28533090 LPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 5w4w A 1.99 BS01 9WG A 1 I15 S17 G18 I23 A36 K38 Y56 M80 M82 E83 L84 L85 L135 I148 D149 I13 S15 G16 I21 A34 K36 Y54 M78 M80 E81 L82 L83 L133 I146 D147 2.7.11.1,2.7.11.26 P48730 28609096 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNML 5w5i A 2.65 BS01 NUC B 1 R38 K151 G153 G154 Y157 Y186 R187 G190 F191 A194 Y218 Y252 R255 Y256 K259 R262 L286 H289 Q290 L293 K336 F339 V341 L344 D345 V372 V373 D379 L413 R30 K129 G131 G132 Y135 Y164 R165 G168 F169 A172 Y196 Y227 R230 Y231 K234 R237 L261 H264 Q265 L268 K297 F300 V302 L305 D306 V333 V334 D340 L374 P09914 QVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLSVGIHNLLAYVKHLKGQNEEALKSLKEAENLVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQEKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAAD 5w7n A 1.80 BS01 NUC B 1 N132 Q134 K180 T183 N71 Q73 K119 T122 3.1.26.4 Q9KEI9 EIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEFLAIVHGLRYLKERNSRKPIYSNSQTAIKWVKDKKAKSTLVRNEETALIWKLVDEAEEWLNTHTYETPILKWQTDKWGEIKADY 5wwr A 3.10 BS01 NUC C 1 T53 T54 Q119 C120 A123 R126 G127 A128 H129 Y131 P133 G134 Q140 F141 K159 K160 G161 A162 R181 K182 F185 S186 G187 L188 K192 G193 P206 F208 D209 L218 Q219 N220 S223 P245 K248 I268 K271 D323 A324 C326 Q331 W339 K342 E343 S346 Y347 P349 L350 R352 K353 S371 T372 C373 F458 T52 T53 Q118 C119 A122 R125 G126 A127 H128 Y130 P132 G133 Q139 F140 K158 K159 G160 A161 R180 K181 F184 S185 G186 L187 K191 G192 P205 F207 D208 L217 Q218 N219 S222 P244 K247 I267 K270 D318 A319 C321 Q326 W334 K337 E338 S341 Y342 P344 L345 R347 K348 S366 T367 C368 F453 2.1.1.- Q8TEA1 28531330 SIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTHLASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKC 5wwr A 3.10 BS02 SFG A 1 L241 C242 A243 A244 P245 G247 K248 D266 K271 D293 G294 D323 L240 C241 A242 A243 P244 G246 K247 D265 K270 D292 G293 D318 2.1.1.- Q8TEA1 28531330 SIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTHLASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKC 5wwr B 3.10 BS02 SFG B 1 C242 A243 A244 P245 G247 K248 D266 K267 K271 F292 D293 G294 D323 P325 C241 A242 A243 P244 G246 K247 D265 K266 K270 F291 D292 G293 D314 P316 2.1.1.- Q8TEA1 28531330 SIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTHLASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKC 5wxm A 2.30 BS01 III U 1 K46 I50 D53 I54 L57 K60 L61 L64 D68 F70 L77 L78 K81 M85 Y148 L149 K19 I23 D26 I27 L30 K33 L34 L37 D41 F43 L50 L51 K54 M58 Y121 L122 P32899 28244370 RDTQVMRTYHIQNREDYHKYNRICGDIRRLANKLSLLPPTDPFRRKHEQLLLDKLYAMGVLTTKSKISDLENKVTVSAICRRRLPVIMHRLKMAETIQDAVKFIEQGHVRVGPNLINDPAYLVTRNMEDYVTWVD 5x4x A 2.31 BS01 SO4 A 1 N183 H196 R215 S216 N147 H160 R179 S180 2.1.1.45 P04818 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMKLPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEM 5x4x A 2.31 BS02 SO4 A 2 R50 R185 L189 R23 R149 L153 2.1.1.45 P04818 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMKLPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEM 5x4y A 2.20 BS01 SO4 A 1 N183 R185 R215 S216 N150 R152 R182 S183 2.1.1.45 P04818 PHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLKALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEM 5x5d A 2.00 BS01 UMP A 1 C195 H196 Q214 R215 S216 G217 D218 G222 N226 H256 Y258 C170 H171 Q189 R190 S191 G192 D193 G197 N201 H231 Y233 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 5x5q A 2.79 BS02 D16 A 1 I108 D218 L221 G222 F225 Y258 M311 I83 D193 L196 G197 F200 Y233 M286 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEM 5x5q B 2.79 BS02 D16 B 1 F80 I108 W109 D218 L221 G222 F225 Y258 I307 K308 M309 M311 F55 I83 W84 D193 L196 G197 F200 Y233 I282 K283 M284 M286 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMA 5x5q D 2.79 BS03 D16 D 1 K77 I108 D218 L221 G222 F225 Y258 K50 I81 D191 L194 G195 F198 Y231 2.1.1.45 P04818 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPT 5x5q F 2.79 BS03 D16 F 1 R78 F80 I108 D218 L221 F225 Y258 R53 F55 I83 D193 L196 F200 Y233 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHP 5x66 A 1.99 BS02 MTX A 1 R78 F80 I108 D218 G222 F225 Y258 M311 R53 F55 I83 D193 G197 F200 Y233 M286 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 5x66 B 1.99 BS01 UMP B 1 R50 C195 H196 R215 S216 D218 G222 N226 H256 Y258 R25 C170 H171 R190 S191 D193 G197 N201 H231 Y233 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 5x66 B 1.99 BS02 MTX B 1 F80 I108 D218 G222 F225 Y258 T306 M311 A312 F55 I83 D193 G197 F200 Y233 T281 M286 A287 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 5x66 C 1.99 BS02 MTX C 1 F80 I108 D218 L221 G222 F225 Y258 M309 M311 A312 F55 I83 D193 L196 G197 F200 Y233 M284 M286 A287 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 5x66 D 1.99 BS03 MTX D 1 R78 F80 I108 D218 G222 F225 Y258 M311 A312 R53 F55 I83 D193 G197 F200 Y233 M286 A287 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 5x66 E 1.99 BS03 MTX E 1 F80 K107 I108 D218 L221 G222 F225 Y258 M311 A312 F55 K82 I83 D193 L196 G197 F200 Y233 M286 A287 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMA 5x66 F 1.99 BS03 MTX F 1 K77 R78 F80 I108 D218 G222 F225 Y258 T306 M311 A312 V313 K52 R53 F55 I83 D193 G197 F200 Y233 T281 M286 A287 V288 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 5x67 A 2.13 BS02 7Z9 A 1 I108 W109 N112 D218 L221 G222 F225 M311 A312 I81 W82 N85 D191 L194 G195 F198 M284 A285 2.1.1.45 P04818 HGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV 5x69 A 2.69 BS01 7ZC A 1 G143 N183 R185 G118 N158 R160 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMA 5x69 A 2.69 BS02 UMP A 1 C195 H196 R215 S216 D218 N226 H256 Y258 C170 H171 R190 S191 D193 N201 H231 Y233 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMA 5x69 B 2.69 BS01 UMP B 1 R50 C195 H196 R215 S216 D218 N226 H256 Y258 R25 C170 H171 R190 S191 D193 N201 H231 Y233 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEM 5x69 B 2.69 BS02 7ZC E 1 G143 E145 N183 R185 G118 E120 N158 R160 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEM 5x69 D 2.69 BS01 7ZC A 1 G143 A144 N183 R185 D186 G118 A119 N158 R160 D161 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKME 5x69 D 2.69 BS03 UMP D 1 R50 C195 R215 S216 D218 N226 H256 Y258 R25 C170 R190 S191 D193 N201 H231 Y233 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKME 5x69 E 2.69 BS02 7ZC E 1 G143 N183 R185 D186 G113 N153 R155 D156 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPT 5x69 F 2.69 BS01 UMP F 1 R50 C195 R215 S216 G217 D218 N226 H256 Y258 R25 C170 R190 S191 G192 D193 N201 H231 Y233 2.1.1.45 P04818 PPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPT 5xai B 2.00 BS01 TMP B 1 D9 K13 E36 R47 F64 R90 T95 Y98 Q99 D9 K13 E36 R47 F64 R90 T95 Y98 Q99 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGV 5xao A 1.80 BS02 CL A 1 M59 G60 R94 G156 V255 M59 G60 R94 G156 V255 Q0UIL6 28584265 MAPSRANTSVIVVGGGGTIGSSTALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLAKIMGVSLRNPVDLQLALEARQMWNEDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLSRDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVETVDGTRYYADKVVLAAGAWSPTLVELHEQCVSKAWVYGHIQLTPEEAARYKNSPVVYNGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDASDVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKLLPNIGKHVVELLEGTLADDLAHAWRWRPGSGDALKSRRSAPAKDLADMPGWNHD 5xao A 1.80 BS03 CL A 2 R284 R303 H308 R284 R303 H308 Q0UIL6 28584265 MAPSRANTSVIVVGGGGTIGSSTALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLAKIMGVSLRNPVDLQLALEARQMWNEDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLSRDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVETVDGTRYYADKVVLAAGAWSPTLVELHEQCVSKAWVYGHIQLTPEEAARYKNSPVVYNGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDASDVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKLLPNIGKHVVELLEGTLADDLAHAWRWRPGSGDALKSRRSAPAKDLADMPGWNHD 5xao A 1.80 BS04 CL A 3 R249 Q331 F332 R249 Q331 F332 Q0UIL6 28584265 MAPSRANTSVIVVGGGGTIGSSTALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLAKIMGVSLRNPVDLQLALEARQMWNEDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLSRDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVETVDGTRYYADKVVLAAGAWSPTLVELHEQCVSKAWVYGHIQLTPEEAARYKNSPVVYNGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDASDVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKLLPNIGKHVVELLEGTLADDLAHAWRWRPGSGDALKSRRSAPAKDLADMPGWNHD 5xao A 1.80 BS05 NA A 1 S48 N53 D54 S48 N53 D54 Q0UIL6 28584265 MAPSRANTSVIVVGGGGTIGSSTALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLAKIMGVSLRNPVDLQLALEARQMWNEDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLSRDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVETVDGTRYYADKVVLAAGAWSPTLVELHEQCVSKAWVYGHIQLTPEEAARYKNSPVVYNGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDASDVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKLLPNIGKHVVELLEGTLADDLAHAWRWRPGSGDALKSRRSAPAKDLADMPGWNHD 5xao A 1.80 BS06 NA A 2 L133 P137 L138 L139 S140 L133 P137 L138 L139 S140 Q0UIL6 28584265 MAPSRANTSVIVVGGGGTIGSSTALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLAKIMGVSLRNPVDLQLALEARQMWNEDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLSRDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVETVDGTRYYADKVVLAAGAWSPTLVELHEQCVSKAWVYGHIQLTPEEAARYKNSPVVYNGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDASDVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKLLPNIGKHVVELLEGTLADDLAHAWRWRPGSGDALKSRRSAPAKDLADMPGWNHD 5xao C 1.80 BS02 CL C 1 E246 R249 Q331 F332 E246 R249 Q331 F332 Q0UIL6 28584265 MAPSRANTSVIVVGGGGTIGSSTALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLAKIMGVSLRNPVDLQLALEARQMWNEDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLSRDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVETVDGTRYYADKVVLAAGAWSPTLVELHEQCVSKAWVYGHIQLTPEEAARYKNSPVVYNGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDASDVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKLLPNIGKHVVELLEGTLADDLAHAWRWRPGSGDALKSRRSAPAKDLADMPGWNHD 5xao C 1.80 BS05 NA C 2 S48 N53 Y237 S48 N53 Y237 Q0UIL6 28584265 MAPSRANTSVIVVGGGGTIGSSTALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLAKIMGVSLRNPVDLQLALEARQMWNEDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLSRDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVETVDGTRYYADKVVLAAGAWSPTLVELHEQCVSKAWVYGHIQLTPEEAARYKNSPVVYNGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDASDVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKLLPNIGKHVVELLEGTLADDLAHAWRWRPGSGDALKSRRSAPAKDLADMPGWNHD 5xb2 B 2.16 BS01 ADP B 1 G10 S11 G12 K13 T14 T15 R139 G176 E177 E178 G10 S11 G12 K13 T14 T15 R139 G176 E177 E178 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLR 5xb2 B 2.16 BS02 TMP B 1 D9 E36 R47 L51 F64 R68 R90 T95 Y98 Q99 R145 D9 E36 R47 L51 F64 R68 R90 T95 Y98 Q99 R145 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLR 5xb2 B 2.16 BS03 MG B 1 T14 D89 T14 D89 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLR 5xb3 A 1.77 BS02 TMP A 1 D9 E36 R47 L51 F64 R90 T95 Y98 Q99 D9 E36 R47 L51 F64 R90 T95 Y98 Q99 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVL 5xb3 B 1.77 BS02 TMP B 1 D9 E36 R47 F64 R90 T95 Y98 Q99 R145 D9 E36 R47 F64 R90 T95 Y98 Q99 R145 2.7.4.9 O67099 MLIAFEGIDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLLFEASRSKLIEEKIIPDLKRDKVVILDRFVLSTIAYQGYGKGLDVEFIKNLNEFATRGVKPDITLLLDIPVDIALRRLKEKNRFENKEFLEKVRKGFLELAKEEENVVVIDASGEEEEVFKEILRALSGVLR 5xe0 A 2.30 BS01 GTP A 1 K155 R159 K163 R170 L171 I172 Y230 T231 G232 Y233 D234 S284 K355 K155 R159 K163 R170 L171 I172 Y230 T231 G232 Y233 D234 S284 K355 F1T146 GEIVSNEKSGVCINAPAKTKLQPSVFHQVFEGSKEPAVLNSKDPRLKTDFEEAIFSKYTGNKIMLMDEYMEEAVDHYVGCLEPLDISVDPIPLESAMYGMDGLEALDLTTSAGFPYLLQGKKKRDIFNRHTRDTTEMTKMLEKYGVDLPFVTFVKDELRSKEKVEKGKSRLIEASSLNDSVAMRVAFGNLYATFHSNPGTATGSAVGCDPDIFWSKIPILLDGEIFAFDYTGYDASLSPVWFACLKKVLIKLGYTHQTSFIDYLCHSVHLYKDRKYIVNGGMPSGSSGTSIFNTMINNIIIRTLLIRVYKGIDLDQFKMIAYGDDVIASYPHKIDPALLAEAGKHYGLVMTPADKGTSFVDTNWENVTFLKRYFRADDQYPFLIHPVMPMKEIHESIRWTKDPRNTQDHVRSLCYLAWHNGEEAYNEFCRKIRSVPVGRALTLPAYSSLRRKWLDSF 5xe9 B 3.10 BS01 6CH B 1 R66 K69 A70 D71 T73 L74 Y77 D79 T81 F137 R48 K51 A52 D53 T55 L56 Y59 D61 T63 F119 Q8DW05 YKLVPQIDTRDCGPAVLASVRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPSVKVTRMSKERFQSEWTGLAIFLAP 5xql A 2.49 BS01 C2E A 1 M1 R31 G33 D35 N36 Y40 M1 R31 G33 D35 N36 Y40 A0A069Q416 MLTIGQLARIFEISTKTLRHYDAIGLFVPARTGSDNGYRYYQPEQIEQLSRILALRRLDVPLEAIDRLKRDGALDDPQRLRHFLQRHQHTLREEISARQRLLAELDRTLATLAHWRIRNMHARIVERPAFSVVGMEYFGSAPTIGQLWERFIPREHEIAGKHDPEVSYGICAQQPNGEFHYVAGFEVQEGWPVPEGMVRFQVPAQKYAVFTHKGTAPQIAESFQAIYSHLLAERGLEPKAGVDFEYYDQRFRGPLDPNSQVDLYIPIY 5xql A 2.49 BS02 C2E A 2 P61 E63 A64 R67 R70 F83 R86 P61 E63 A64 R67 R70 F83 R86 A0A069Q416 MLTIGQLARIFEISTKTLRHYDAIGLFVPARTGSDNGYRYYQPEQIEQLSRILALRRLDVPLEAIDRLKRDGALDDPQRLRHFLQRHQHTLREEISARQRLLAELDRTLATLAHWRIRNMHARIVERPAFSVVGMEYFGSAPTIGQLWERFIPREHEIAGKHDPEVSYGICAQQPNGEFHYVAGFEVQEGWPVPEGMVRFQVPAQKYAVFTHKGTAPQIAESFQAIYSHLLAERGLEPKAGVDFEYYDQRFRGPLDPNSQVDLYIPIY 5xsq A 2.60 BS01 III B 1 R206 F207 V213 K214 L217 L221 Q222 K223 L230 R235 K247 L250 S251 L253 A254 G257 A260 R202 F203 V209 K210 L213 L217 Q218 K219 L226 R231 K243 L246 S247 L249 A250 G253 A256 Q6UY69 KKVILFDTNHQVSICNQIIDAINSGIDLGDLLEGGLLTLCVEHYYNSDKDKFNTSPIAKYLRDAGYEFDVIKNADATRFLDVIPNEPHYSPLILALKTLESTESQRGRIGLFLSFCSLFLPKLVVGDRASIEKALRQVTVHQEQGIVTYPNHWLTTGHMKVIFGILRSSFILKFVLIHQGVNLVTGHDAYDSIISNSVGQTRFSGLLIVKTVLEFILQKTDSGVTLHPLVRTSKVKNEVASFKQALSNLARHGEYAPFARVLNLSGINNLEHGLYPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAAHDAEVKL 5xsq C 2.60 BS01 III D 1 R206 F207 V213 K214 L217 E218 L221 Q222 K223 V228 L230 R235 V243 K247 S251 L253 A254 G257 A260 R202 F203 V209 K210 L213 E214 L217 Q218 K219 V224 L226 R231 V239 K243 S247 L249 A250 G253 A256 Q6UY69 KKVILFDTNHQVSICNQIIDAINSGIDLGDLLEGGLLTLCVEHYYNSDKDKFNTSPIAKYLRDAGYEFDVIKNADATRFLDVIPNEPHYSPLILALKTLESTESQRGRIGLFLSFCSLFLPKLVVGDRASIEKALRQVTVHQEQGIVTYPNHWLTTGHMKVIFGILRSSFILKFVLIHQGVNLVTGHDAYDSIISNSVGQTRFSGLLIVKTVLEFILQKTDSGVTLHPLVRTSKVKNEVASFKQALSNLARHGEYAPFARVLNLSGINNLEHGLYPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAAHDAEVKL 5xsq E 2.60 BS01 III F 1 R206 F207 V213 K214 L217 L221 V228 R235 K247 L250 S251 L253 A254 G257 A260 P261 R198 F199 V205 K206 L209 L213 V220 R227 K239 L242 S243 L245 A246 G249 A252 P253 Q6UY69 KKVILFDTNHQVSICNQIIDAINSGIDLGDLLEGGLLTLCVEHYYNSDKDKFNTSPIAKYLRDAGYEFDVIKNADATRFLDVIPNEPHYSPLILALKTLESTESQRGRIGLFLSFCSLFLPKLVVGDRASIEKALRQVTVHQEQGIVTYPNHWLTTGHMKVIFGILRSSFILKFVLIHQGVNLDAYDSIISNSVGQTRFSGLLIVKTVLEFILQKTDSGVTLHPLVRTSKVKNEVASFKQALSNLARHGEYAPFARVLNLSGINNLEHGLYPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAAHDAEVKL