5b4x A 3.20 BS01 CA A 1 T1961 D1963 D1994 S1995 D2125 T8 D10 D41 S42 D167 3.4.21.- Q60841 NPVLLLDTFDFGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLSVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLCYHSSLCSTEHHPSSTYYAGTTQGWRREVVHFGKLHLAGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCYGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLVTRDLDLSHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEMPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFSTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPSYTRSQATRFRWHQPAPFDKQQTWAIDNVYIGDGCLDMCSGHGRCVQGSCVCDEQWGGLYCDEPETSLPTQLKDNFNRAPSNQNWLTVSGGKLSTVCGAVASGLALHFSGGCSRLLVTVDLNLTNAEFIQFYFMYGCLITPSNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLISRLENLY 5b4x A 3.20 BS02 CA A 2 D2173 L2198 G2201 N2202 D2310 D215 L240 G243 N244 D352 3.4.21.- Q60841 NPVLLLDTFDFGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLSVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLCYHSSLCSTEHHPSSTYYAGTTQGWRREVVHFGKLHLAGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCYGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLVTRDLDLSHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEMPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFSTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPSYTRSQATRFRWHQPAPFDKQQTWAIDNVYIGDGCLDMCSGHGRCVQGSCVCDEQWGGLYCDEPETSLPTQLKDNFNRAPSNQNWLTVSGGKLSTVCGAVASGLALHFSGGCSRLLVTVDLNLTNAEFIQFYFMYGCLITPSNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLISRLENLY 5b4x A 3.20 BS03 CA A 3 D2327 T2351 G2352 D2353 D2474 N2475 D369 T393 G394 D395 D516 N517 3.4.21.- Q60841 NPVLLLDTFDFGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLSVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLCYHSSLCSTEHHPSSTYYAGTTQGWRREVVHFGKLHLAGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCYGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLVTRDLDLSHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEMPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFSTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPSYTRSQATRFRWHQPAPFDKQQTWAIDNVYIGDGCLDMCSGHGRCVQGSCVCDEQWGGLYCDEPETSLPTQLKDNFNRAPSNQNWLTVSGGKLSTVCGAVASGLALHFSGGCSRLLVTVDLNLTNAEFIQFYFMYGCLITPSNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLISRLENLY 5b4x A 3.20 BS04 CA A 4 N2522 S2549 L2551 D2657 N2658 N564 S591 L593 D699 N700 3.4.21.- Q60841 NPVLLLDTFDFGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLSVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLCYHSSLCSTEHHPSSTYYAGTTQGWRREVVHFGKLHLAGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCYGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLVTRDLDLSHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEMPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFSTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPSYTRSQATRFRWHQPAPFDKQQTWAIDNVYIGDGCLDMCSGHGRCVQGSCVCDEQWGGLYCDEPETSLPTQLKDNFNRAPSNQNWLTVSGGKLSTVCGAVASGLALHFSGGCSRLLVTVDLNLTNAEFIQFYFMYGCLITPSNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLISRLENLY 5b4x B 3.20 BS01 CA B 1 W63 D66 D68 D70 D76 E77 W20 D23 D25 D27 D33 E34 D3DQ39 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRA 5b4x B 3.20 BS02 CA B 2 W102 K103 C104 D105 E107 E109 D115 E116 W59 K60 C61 D62 E64 E66 D72 E73 D3DQ39 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRA 5b4x B 3.20 BS03 CA B 3 E209 D223 L224 G227 E81 D95 L96 G99 D3DQ39 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRA 5b4x B 3.20 BS04 CA B 4 G235 D246 I247 E249 N262 Y263 G265 Y266 G107 D118 I119 E121 N134 Y135 G137 Y138 D3DQ39 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRA 5b4x C 3.20 BS01 CA C 1 T1961 F1962 D1963 D1994 S1995 D2125 T7 F8 D9 D40 S41 D166 3.4.21.- Q60841 PVLLLDTFDFGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLSVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLCYHSSLCSTEHHPSSTYYAGTTQGWRREVVHFGKLHLAGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCYGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLVTRDLDLSHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEMPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFSTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPSYTRSQATRFRWHQPAPFDKQQTWAIDNVYIGDGCLDMCSGHGRCVQGSCVCDEQWGGLYCDEPETSLPTQLKDNFNRAPSNQNWLTVSGGKLSTVCGAVASGLALHFSGGCSRLLVTVDLNLTNAEFIQFYFMYGCLITPSNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLISRLENLY 5b4x C 3.20 BS02 CA C 2 D2173 E2175 G2201 N2202 D2310 Q2311 D214 E216 G242 N243 D351 Q352 3.4.21.- Q60841 PVLLLDTFDFGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLSVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLCYHSSLCSTEHHPSSTYYAGTTQGWRREVVHFGKLHLAGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCYGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLVTRDLDLSHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEMPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFSTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPSYTRSQATRFRWHQPAPFDKQQTWAIDNVYIGDGCLDMCSGHGRCVQGSCVCDEQWGGLYCDEPETSLPTQLKDNFNRAPSNQNWLTVSGGKLSTVCGAVASGLALHFSGGCSRLLVTVDLNLTNAEFIQFYFMYGCLITPSNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLISRLENLY 5b4x C 3.20 BS03 CA C 3 D2327 T2351 G2352 D2353 D2474 N2475 D368 T392 G393 D394 D515 N516 3.4.21.- Q60841 PVLLLDTFDFGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLSVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLCYHSSLCSTEHHPSSTYYAGTTQGWRREVVHFGKLHLAGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCYGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLVTRDLDLSHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEMPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFSTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPSYTRSQATRFRWHQPAPFDKQQTWAIDNVYIGDGCLDMCSGHGRCVQGSCVCDEQWGGLYCDEPETSLPTQLKDNFNRAPSNQNWLTVSGGKLSTVCGAVASGLALHFSGGCSRLLVTVDLNLTNAEFIQFYFMYGCLITPSNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLISRLENLY 5b4x C 3.20 BS04 CA C 4 N2522 S2549 G2550 L2551 D2657 N2658 N563 S590 G591 L592 D698 N699 3.4.21.- Q60841 PVLLLDTFDFGPREDNWFFYPGGNIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLSVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLCYHSSLCSTEHHPSSTYYAGTTQGWRREVVHFGKLHLAGSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCYGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLVTRDLDLSHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEMPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFSTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDSFLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPSYTRSQATRFRWHQPAPFDKQQTWAIDNVYIGDGCLDMCSGHGRCVQGSCVCDEQWGGLYCDEPETSLPTQLKDNFNRAPSNQNWLTVSGGKLSTVCGAVASGLALHFSGGCSRLLVTVDLNLTNAEFIQFYFMYGCLITPSNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLISRLENLY 5b4x D 3.20 BS01 CA D 1 W63 D66 D68 D70 D76 E77 W20 D23 D25 D27 D33 E34 D3DQ39 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRA 5b4x D 3.20 BS02 CA D 2 W102 K103 D105 E107 E109 D115 E116 W59 K60 D62 E64 E66 D72 E73 D3DQ39 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRA 5b4x D 3.20 BS03 CA D 3 E209 D223 L224 E81 D95 L96 D3DQ39 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRA 5b4x D 3.20 BS04 CA D 4 D246 I247 E249 N262 Y263 G265 Y266 D118 I119 E121 N134 Y135 G137 Y138 D3DQ39 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRA 5b4y B 1.90 BS01 CA B 1 W63 D66 D68 D70 D76 E77 W20 D23 D25 D27 D33 E34 Q14114 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCT 5b4y B 1.90 BS02 CA B 2 W102 D105 E107 E109 D115 E116 W59 D62 E64 E66 D72 E73 Q14114 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCT 5b53 A 2.91 BS01 PLP A 1 K46 N76 G182 V183 G184 T185 G186 G187 T188 E228 G229 I230 S272 P298 D299 Y304 K45 N75 G181 V182 G183 T184 G185 G186 T187 E227 G228 I229 S271 P297 D298 Y303 2.5.1.47 Q8REP3 EQKKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISDEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRV 5b54 A 2.07 BS01 PLP A 1 K46 N76 G182 V183 G184 T185 G186 T188 G229 I230 S272 P298 D299 Y304 K41 N71 G177 V178 G179 T180 G181 T183 G224 I225 S267 P293 D294 Y299 2.5.1.47 Q8REP3 MKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISDEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRVI 5b54 B 2.07 BS01 PLP B 1 K46 N76 V183 G184 T185 G186 G187 T188 G229 I230 S272 P298 D299 K47 N77 V184 G185 T186 G187 G188 T189 G230 I231 S273 P299 D300 2.5.1.47 Q8REP3 GSEQKKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISDEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRV 5b54 C 2.07 BS01 PLP C 1 K46 N76 V183 G184 T185 G186 G187 T188 G229 I230 S272 P298 D299 Y304 K43 N73 V180 G181 T182 G183 G184 T185 G226 I227 S269 P295 D296 Y301 2.5.1.47 Q8REP3 KKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISDEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRVI 5b54 D 2.07 BS01 PLP D 1 K46 N76 G182 V183 G184 T185 G186 T188 G229 I230 S272 P298 D299 Y304 K43 N73 G179 V180 G181 T182 G183 T185 G226 I227 S269 P295 D296 Y301 2.5.1.47 Q8REP3 KKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISDEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRV 5b55 A 2.14 BS01 PLP A 1 K46 N76 G184 T185 G186 G187 T188 E228 G229 I230 S272 P298 D299 Y304 K44 N74 G182 T183 G184 G185 T186 E226 G227 I228 S270 P296 D297 Y302 2.5.1.47 Q8REP3 QKKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISNEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRVI 5b55 A 2.14 BS02 0JO A 1 K46 T73 S74 N76 T77 Q147 G182 V183 G184 T185 G186 T188 G229 I230 N232 S272 P298 D299 Y304 K44 T71 S72 N74 T75 Q145 G180 V181 G182 T183 G184 T186 G227 I228 N230 S270 P296 D297 Y302 2.5.1.47 Q8REP3 QKKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISNEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRVI 5b55 B 2.14 BS01 PLP B 1 K46 N76 G184 T185 G186 G187 T188 E228 G229 I230 S272 D299 Y304 K44 N74 G182 T183 G184 G185 T186 E226 G227 I228 S270 D297 Y302 2.5.1.47 Q8REP3 QKKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISNEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRV 5b55 B 2.14 BS02 0JO B 1 K46 T73 S74 N76 T77 Q147 G182 V183 G184 T185 G186 T188 G229 I230 N232 S272 P298 D299 Y304 K44 T71 S72 N74 T75 Q145 G180 V181 G182 T183 G184 T186 G227 I228 N230 S270 P296 D297 Y302 2.5.1.47 Q8REP3 QKKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISNEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRV 5eg6 C 2.09 BS01 NUC B 1 K84 Y86 S191 K192 K32 Y34 S137 K138 P31266 PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKQSLKNADLCIASGTKVALFNRLTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTPE 5eg6 C 2.09 BS02 III R 1 G234 N235 F236 H249 E259 E260 F261 T262 V263 R264 D265 K275 G282 M283 A284 L285 P286 I331 I332 Q333 F334 G175 N176 F177 H190 E200 E201 F202 T203 V204 R205 D206 K216 G223 M224 A225 L226 P227 I272 I273 Q274 F275 P31266 PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKQSLKNADLCIASGTKVALFNRLTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTPE 5eg6 C 2.09 BS03 NUC A 1 K90 R91 F92 K192 R218 T223 K38 R39 F40 K138 R162 T164 P31266 PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKQSLKNADLCIASGTKVALFNRLTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTPE 5frb A 2.99 BS01 HEM A 1 Y136 L143 K147 L304 G308 S311 L367 P372 I376 R378 P455 F456 H461 C463 I464 G465 Y87 L94 K98 L255 G259 S262 L318 P323 I327 R329 P406 F407 H412 C414 I415 G416 1.14.13.70 A0A0J5PJX1 KTPPVVFHWFPFIGSTISYGIDPYKFFFDCRAKYGDIFTFILLGKKTTVYLGTKGNDFILNGKLRDVCAEEVYSPLTTPVFGRHVVYDCPNAKLMEQKKFVKYGLTSDALRSYVPLITDEVESFVKNSPAFQGHKGVFDVCKTIAEITIYTASRSLQGKEVRSKFDSTFAELYHNLDMGFAPINFMLPWAPLPHNRKRDAAQRKLTETYMEIIKARRQAGSKKDSEDMVWNLMSCVYKNGTPVPDEEIAHMMIALLMAGQHSSSSTASWIVLRLATRPDIMEELYQEQIRVLGSDLPPLTYDNLQKLDLHAKVIKETLRLHAPIHSIIRAVKNPMAVDGTSYVIPTSHNVLSSPGVTARSEEHFPNPLEWNPHRWDENIAASAEDDEKVDYGYGLVSKGTNSPYLPFGAGRHRCIGEQFAYLQLGTITAVLVRLFRFRNLPGVDGIPDTDYSSLFSKPLGRSFVEFEKRH 5frb A 2.99 BS02 VT2 A 1 Y68 G69 F130 Y136 A303 A307 H374 Y500 S501 S502 L503 F504 Y19 G20 F81 Y87 A254 A258 H325 Y451 S452 S453 L454 F455 1.14.13.70 A0A0J5PJX1 KTPPVVFHWFPFIGSTISYGIDPYKFFFDCRAKYGDIFTFILLGKKTTVYLGTKGNDFILNGKLRDVCAEEVYSPLTTPVFGRHVVYDCPNAKLMEQKKFVKYGLTSDALRSYVPLITDEVESFVKNSPAFQGHKGVFDVCKTIAEITIYTASRSLQGKEVRSKFDSTFAELYHNLDMGFAPINFMLPWAPLPHNRKRDAAQRKLTETYMEIIKARRQAGSKKDSEDMVWNLMSCVYKNGTPVPDEEIAHMMIALLMAGQHSSSSTASWIVLRLATRPDIMEELYQEQIRVLGSDLPPLTYDNLQKLDLHAKVIKETLRLHAPIHSIIRAVKNPMAVDGTSYVIPTSHNVLSSPGVTARSEEHFPNPLEWNPHRWDENIAASAEDDEKVDYGYGLVSKGTNSPYLPFGAGRHRCIGEQFAYLQLGTITAVLVRLFRFRNLPGVDGIPDTDYSSLFSKPLGRSFVEFEKRH 5gsr A 2.20 BS01 III P 1 Y7 V9 A24 F45 Y59 E62 Q63 R66 D70 W73 V76 S77 T80 A81 Y84 F95 R97 T143 K146 W147 A150 D152 Y155 Y156 Y159 E163 W167 Y171 Y7 V9 A24 F45 Y59 E62 Q63 R66 D70 W73 V76 S77 T80 A81 Y84 F95 R97 T143 K146 W147 A150 D152 Y155 Y156 Y159 E163 W167 Y171 P01902 27903740 GPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYQQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRW 5gsr C 2.20 BS01 III Q 1 Y7 V9 A24 F45 Y59 E62 Q63 R66 D70 W73 V76 S77 T80 A81 Y84 F95 R97 F99 Q114 T143 K146 W147 D152 Y155 Y156 Y159 E163 W167 Y171 Y7 V9 A24 F45 Y59 E62 Q63 R66 D70 W73 V76 S77 T80 A81 Y84 F95 R97 F99 Q114 T143 K146 W147 D152 Y155 Y156 Y159 E163 W167 Y171 P01902 27903740 GPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYQQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRW 5gsv A 2.00 BS01 III C 1 Y7 V9 F45 Y59 Q63 R66 S69 D70 W73 S77 T80 Y84 R97 F99 Y123 T143 K146 W147 A150 D152 Y155 Y156 Y159 E163 W167 Y171 Y7 V9 F45 Y59 Q63 R66 S69 D70 W73 S77 T80 Y84 R97 F99 Y123 T143 K146 W147 A150 D152 Y155 Y156 Y159 E163 W167 Y171 P01902 27903740 GPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYQQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRW 5gug A 7.40 BS01 I3P A 1 T267 G268 R269 A275 K508 Y567 T255 G256 R257 A263 K444 Y481 P11881 SSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKASTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRWNSLFRFKHLATGHYLAAEVMVYSLVSVPEGNDISSIFELDPVPRNSYVRLRHLCTNTWVHSTNIPKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPSRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEF 5gug B 7.40 BS01 I3P B 1 T267 G268 R269 R504 K508 Y567 R568 K569 T254 G255 R256 R439 K443 Y480 R481 K482 P11881 SSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKASTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRWNSLFRFKHLATGHYLAAEVMVYSLVSVPEGNDISSIFELDPVPRNSYVRLRHLCTNTWVHSTNIPKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPSRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEF 5icj A 2.40 BS01 69Y A 1 E70 M74 M77 I93 A96 V97 W100 I113 F126 A130 S134 T138 L141 L167 D168 E59 M63 M66 I82 A85 V86 W89 I102 F115 A119 S123 T127 L130 L156 D157 O53623 28302858 SAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG 5icj B 2.40 BS01 69Y B 1 E70 M74 I93 A96 V97 W100 I113 F126 A130 S134 T138 L141 L167 D168 E59 M63 I78 A81 V82 W85 I98 F111 A115 S119 T123 L126 L152 D153 O53623 28302858 SAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG 5igi A 1.20 BS01 GMP A 1 I38 V50 R52 Y94 M96 L97 E98 D99 S100 T101 G204 H205 L207 I218 D219 I37 V49 R51 Y93 M95 L96 E97 D98 S99 T100 G203 H204 L206 I217 D218 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igi A 1.20 BS02 ZIT A 1 M103 I105 S110 P112 D200 Y202 H205 E222 A234 M237 V238 G273 T276 Y277 F280 M102 I104 S109 P111 D199 Y201 H204 E221 A233 M236 V237 G272 T275 Y276 F279 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igj A 1.40 BS01 GMP A 1 I38 V50 R52 Y94 M96 L97 E98 D99 S100 T101 G204 H205 L207 I218 D219 I37 V49 R51 Y93 M95 L96 E97 D98 S99 T100 G203 H204 L206 I217 D218 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igj A 1.40 BS02 CTY A 1 M103 I105 P112 D200 Y202 A234 M237 V238 G273 Y277 F280 M102 I104 P111 D199 Y201 A233 M236 V237 G272 Y276 F279 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igp A 1.60 BS01 GDP A 1 I38 V50 R52 Y94 M96 L97 E98 D99 S100 T101 G204 H205 L207 I218 D219 I37 V49 R51 Y93 M95 L96 E97 D98 S99 T100 G203 H204 L206 I217 D218 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igp A 1.60 BS02 ERY A 1 M103 I105 S110 P112 D200 Y202 A234 M237 V238 G273 Y277 F280 M102 I104 S109 P111 D199 Y201 A233 M236 V237 G272 Y276 F279 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igr A 1.60 BS01 GDP A 1 I38 V50 R52 Y94 M96 L97 E98 D99 S100 T101 G204 H205 L207 I218 D219 I37 V49 R51 Y93 M95 L96 E97 D98 S99 T100 G203 H204 L206 I217 D218 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igr A 1.60 BS02 ZIO A 1 M103 S110 D200 Y202 A233 A234 M237 G273 Y277 F280 M102 S109 D199 Y201 A232 A233 M236 G272 Y276 F279 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igs A 1.38 BS01 ZIO A 1 M103 I105 S110 D200 Y202 A233 A234 G273 Y277 F280 M102 I104 S109 D199 Y201 A232 A233 G272 Y276 F279 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igs A 1.38 BS02 GMP A 1 I38 V50 R52 Y94 M96 L97 E98 D99 S100 T101 G204 H205 L207 I218 D219 I37 V49 R51 Y93 M95 L96 E97 D98 S99 T100 G203 H204 L206 I217 D218 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igt A 1.39 BS01 GMP A 1 I38 V50 R52 Y94 M96 L97 E98 D99 S100 T101 G204 H205 L207 I218 D219 I37 V49 R51 Y93 M95 L96 E97 D98 S99 T100 G203 H204 L206 I217 D218 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igt A 1.39 BS02 ERY A 1 M103 I105 S110 P112 D200 Y202 A234 M237 V238 G273 Y277 F280 M102 I104 S109 P111 D199 Y201 A233 M236 V237 G272 Y276 F279 Q47396 TVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDDGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFALDSGNEEYLAAAKAQLAAAE 5igv A 1.55 BS01 MG A 1 H205 D219 H204 D218 O32553 SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igv A 1.55 BS02 CA A 1 D219 T221 D218 T220 O32553 SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igv A 1.55 BS03 GDP A 1 N27 F33 F37 V47 Y92 K94 L95 G97 P99 G204 H205 M207 I218 D219 N26 F32 F36 V46 Y91 K93 L94 G96 P98 G203 H204 M206 I217 D218 O32553 SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igv A 1.55 BS04 ZIT A 1 I103 G108 N109 Y110 D200 V201 H202 H205 E222 I233 F234 R237 A238 S276 I277 F280 Y289 M292 I102 G107 N108 Y109 D199 V200 H201 H204 E221 I232 F233 R236 A237 S275 I276 F279 Y288 M291 O32553 SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igw A 2.10 BS01 GDP A 1 N27 F33 F37 V47 R49 Y92 K94 L95 H205 M207 I218 D219 N26 F32 F36 V46 R48 Y91 K93 L94 H202 M204 I215 D216 O32553 SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igw A 2.10 BS02 MG A 1 D219 T221 D216 T218 O32553 SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igw A 2.10 BS03 MG A 2 H205 D219 H202 D216 O32553 SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igw A 2.10 BS04 CTY A 1 I103 G108 D200 V201 H202 E222 I233 F234 R237 A238 S276 I277 F280 I102 G105 D197 V198 H199 E219 I230 F231 R234 A235 S273 I274 F277 O32553 SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igy A 1.45 BS01 CA A 1 H205 D219 H202 D216 O32553 DIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALE 5igy A 1.45 BS02 GDP A 1 N27 S29 G30 L31 D32 F33 A35 F37 V47 R49 Y92 K94 L95 G97 P99 G204 H205 M207 I218 D219 N24 S26 G27 L28 D29 F30 A32 F34 V44 R46 Y89 K91 L92 G94 P96 G201 H202 M204 I215 D216 O32553 DIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALE 5igy A 1.45 BS03 ERY A 1 H105 G108 N109 Y110 D200 V201 H202 E222 H230 I233 F234 R237 Y273 S276 I277 F280 Y289 M292 H102 G105 N106 Y107 D197 V198 H199 E219 H227 I230 F231 R234 Y270 S273 I274 F277 Y286 M289 O32553 DIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALE 5igz A 1.60 BS01 GDP A 1 N27 S29 G30 L31 D32 F33 A35 F37 R49 Y92 K94 L95 G97 P99 T102 G204 H205 M207 I218 D219 N27 S29 G30 L31 D32 F33 A35 F37 R49 Y92 K94 L95 G97 P99 T102 G204 H205 M207 I218 D219 O32553 MSKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igz A 1.60 BS02 MG A 1 D32 D219 T221 D32 D219 T221 O32553 MSKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igz A 1.60 BS03 MG A 2 H205 D219 H205 D219 O32553 MSKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5igz A 1.60 BS04 SPR A 1 L31 D32 R59 I103 H105 G108 N109 Y110 D200 H202 E222 F234 R237 Y273 S276 I277 E279 F280 E288 Y289 M292 L31 D32 R59 I103 H105 G108 N109 Y110 D200 H202 E222 F234 R237 Y273 S276 I277 E279 F280 E288 Y289 M292 O32553 MSKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5ih0 A 1.65 BS01 MG A 1 H205 D219 H205 D219 O32553 MSKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAMKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5ih0 A 1.65 BS02 GDP A 1 F33 A35 F37 V47 R49 K94 L95 G97 V98 P99 G204 H205 M207 I218 D219 F33 A35 F37 V47 R49 K94 L95 G97 V98 P99 G204 H205 M207 I218 D219 O32553 MSKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAMKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5ih0 A 1.65 BS03 ERY A 1 I103 H105 G108 N109 Y110 D200 V201 H202 E222 H230 I233 F234 R237 A238 Y273 S276 I277 F280 Y289 M292 I103 H105 G108 N109 Y110 D200 V201 H202 E222 H230 I233 F234 R237 A238 Y273 S276 I277 F280 Y289 M292 O32553 MSKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAMKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5ih1 A 1.31 BS01 GDP A 1 F37 R49 Y92 K94 L95 G97 P99 H205 M207 I218 D219 F35 R47 Y90 K92 L93 G95 P97 H203 M205 I216 D217 O32553 KDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5ih1 A 1.31 BS02 MG A 1 H205 D219 H203 D217 O32553 KDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5ih1 A 1.31 BS03 CA A 1 D219 T221 D217 T219 O32553 KDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5ih1 A 1.31 BS04 6BQ A 1 H105 G108 N109 Y110 H202 E222 F234 R237 A238 Y273 S276 I277 E279 F280 V283 Y289 M292 H103 G106 N107 Y108 H200 E220 F232 R235 A236 Y271 S274 I275 E277 F278 V281 Y287 M290 O32553 KDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5irr A 2.04 BS01 MG A 1 T124 T146 T20 T42 A8IYS5 IWKKKYIKLIVVGDSGLGKTTLIKSLISIPGERLQVHDGSYTPTEQFRRDPESLSSTVSWRDEEDRVIWVYKIQDTPGYGDELDVFRNLKMVQDYIESQNRKWLELEQARIEDPRVDLCIFCIPPHRLRPIDLKYMFELGKHVPVVPVVTKADTMTIREANTYRTEVANRIANPMVPGIHDKINIFKFERDTLERAGVQDHATPHPPFLVIASNDISEELAAAEPPLFWPERRYPWGTAEAFNKEHSDLLAVRALLMKEALEEISKTKRARYEAWRRT 5irr A 2.04 BS02 GSP A 1 S119 G120 L121 G122 K123 T124 T125 H141 Y145 T146 G182 K263 D265 I323 A324 R344 Y346 S15 G16 L17 G18 K19 T20 T21 H37 Y41 T42 G78 K151 D153 I211 A212 R232 Y234 A8IYS5 IWKKKYIKLIVVGDSGLGKTTLIKSLISIPGERLQVHDGSYTPTEQFRRDPESLSSTVSWRDEEDRVIWVYKIQDTPGYGDELDVFRNLKMVQDYIESQNRKWLELEQARIEDPRVDLCIFCIPPHRLRPIDLKYMFELGKHVPVVPVVTKADTMTIREANTYRTEVANRIANPMVPGIHDKINIFKFERDTLERAGVQDHATPHPPFLVIASNDISEELAAAEPPLFWPERRYPWGTAEAFNKEHSDLLAVRALLMKEALEEISKTKRARYEAWRRT 5irr B 2.04 BS01 MG B 1 T124 T146 T21 T43 A8IYS5 KIWKKKYIKLIVVGDSGLGKTTLIKSLISIPGERLQVHDGSYTPTEQFRRDPESLSSTVSWRDEEDRVIWVYKIQDTPGYGDELDVFRNLKMVQDYIESQNRKWLELEQARIEDPRVDLCIFCIPPHRLRPIDLKYMFELGKHVPVVPVVTKADTMTIREANTYRTEVANRIANPMVPGIHDKINIFKFERDTLERAGVQDHATPHPPFLVIASNDISEELAAAEPPLFWPERRYPWGTAEAFNKEHSDLLAVRALLMKEALEEISKTKRARYEAWRRTTL 5irr B 2.04 BS02 GSP B 1 S119 G120 L121 G122 K123 T124 T125 H141 Y145 T146 G182 K263 D265 I323 A324 R344 Y346 S16 G17 L18 G19 K20 T21 T22 H38 Y42 T43 G79 K152 D154 I212 A213 R233 Y235 A8IYS5 KIWKKKYIKLIVVGDSGLGKTTLIKSLISIPGERLQVHDGSYTPTEQFRRDPESLSSTVSWRDEEDRVIWVYKIQDTPGYGDELDVFRNLKMVQDYIESQNRKWLELEQARIEDPRVDLCIFCIPPHRLRPIDLKYMFELGKHVPVVPVVTKADTMTIREANTYRTEVANRIANPMVPGIHDKINIFKFERDTLERAGVQDHATPHPPFLVIASNDISEELAAAEPPLFWPERRYPWGTAEAFNKEHSDLLAVRALLMKEALEEISKTKRARYEAWRRTTL 5iwu A 1.30 BS01 ERY A 1 H105 G108 N109 Y110 D200 V201 H202 E222 H230 I233 F234 R237 Y273 S276 I277 F280 Y289 M292 H105 G108 N109 Y110 D200 V201 H202 E222 H230 I233 F234 R237 Y273 S276 I277 F280 Y289 M292 O32553 MSKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV 5jfe A 2.03 BS01 FAD A 1 R78 H79 R80 I81 N169 L173 R174 H178 R75 H76 R77 I78 N166 L170 R171 H175 2.1.1.148 Q9WYT0 HMKIDILDKGFVELVDVMGNDLSAVRAARVSFDMEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGRYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILK 5jfe A 2.03 BS02 UMC A 1 Q75 R78 R174 Q72 R75 R171 2.1.1.148 Q9WYT0 HMKIDILDKGFVELVDVMGNDLSAVRAARVSFDMEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGRYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILK 5jfy A 2.10 BS01 ZN A 1 H80 C110 C113 H60 C90 C93 H2EMX8 GHQQAVLDSDHKFLTQAVEEAYKGVDCGDGGPFGAVIVHKNEVVASCHNMVLKYTDPTAHAEVTAIREACKKLNQIELSECEIYASCEPCPMCFGAIHLSRLKRLVYGAKAEAAIAIGF 5jfy B 2.10 BS01 ZN B 1 H80 C110 C113 H60 C90 C93 H2EMX8 GHQQAVLDSDHKFLTQAVEEAYKGVDCGDGGPFGAVIVHKNEVVASCHNMVLKYTDPTAHAEVTAIREACKKLNQIELSECEIYASCEPCPMCFGAIHLSRLKRLVYGAKAEAAIAIGF 5jfy C 2.10 BS01 ZN C 1 H80 C110 C113 H61 C91 C94 H2EMX8 AGHQQAVLDSDHKFLTQAVEEAYKGVDCGDGGPFGAVIVHKNEVVASCHNMVLKYTDPTAHAEVTAIREACKKLNQIELSECEIYASCEPCPMCFGAIHLSRLKRLVYGAKAEAAIAIGFD 5jfy D 2.10 BS01 ZN D 1 H80 C110 C113 H60 C90 C93 H2EMX8 GHQQAVLDSDHKFLTQAVEEAYKGVDCGDGGPFGAVIVHKNEVVASCHNMVLKYTDPTAHAEVTAIREACKKLNQIELSECEIYASCEPCPMCFGAIHLSRLKRLVYGAEAAIAIGF 5jgg A 1.70 BS01 HEM A 1 M32 Y42 F43 H45 Y46 H59 K62 A66 L84 L87 H88 L92 V94 N98 F99 L102 L137 M32 Y42 F43 H45 Y46 H59 K62 A66 L84 L87 H88 L92 V94 N98 F99 L102 L137 TLTSADKSHVKSIWSKASGKAEELGAEALGRMLEVFPNTKTYFSHYADLSVTSGQVHTHGKKILDAITTAVNHIDDITGVLTALSTLHAKTLRVDPANFKILSHTILVVLALYFPADFTPEVHLACDKFLASVSHTLATKYR 5jgg B 1.70 BS01 HEM B 1 T38 Y41 F42 H63 V67 S70 L88 F91 H92 L96 V98 N102 F103 F106 I137 L141 T37 Y40 F41 H62 V66 S69 L87 F90 H91 L95 V97 N101 F102 F105 I136 L140 EWTDSERFAIVTLWAKVNVETVGAQALVRLLVVYPWTQRYFGAFGNISDAAAIAGNAQVHAHGKTVLDSVGNAIAHMDDVADAFTALSTFHSETLHVDPDNFQHFGDCLSIVLAATFGTAYTPDVQAAWQKMIAVIISALSKEY 5jhh B 2.30 BS01 RA0 B 1 G14 A15 G17 K18 T19 C20 K118 D120 L121 A161 K162 G12 A13 G15 K16 T17 C18 K116 D118 L119 A159 K160 P61586 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 5jhh F 2.30 BS01 RA0 F 1 G14 A15 G17 K18 T19 C20 V35 A61 K118 D120 S160 A161 K162 G12 A13 G15 K16 T17 C18 V33 A59 K116 D118 S158 A159 K160 P61586 AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 5ji0 A 1.98 BS01 III F 1 F277 V280 K284 L294 Q297 V298 T449 F450 E453 F41 V44 K48 L58 Q61 V62 T210 F211 E214 P19793 NEDMPVERILEAELAVEPKTETYVENDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRFIGLKCLEHLFFFKLIGDTTFLMEML 5ji0 A 1.98 BS02 9CR A 1 I268 Q275 W305 F313 R316 L326 A327 V342 C432 L436 I32 Q39 W69 F77 R80 L90 A91 V106 C196 L200 P19793 NEDMPVERILEAELAVEPKTETYVENDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRFIGLKCLEHLFFFKLIGDTTFLMEML 5ji0 D 1.98 BS01 III E 1 Q294 K301 F306 L311 N312 Q314 V315 T316 L318 K319 L468 E471 Q86 K93 F98 L103 N104 Q106 V107 T108 L110 K111 L260 E263 P37231 GPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 5ji0 D 1.98 BS02 BRL D 1 F282 G284 C285 Q286 S289 H323 Y327 V339 I341 M364 H449 L453 Y473 F74 G76 C77 Q78 S81 H115 Y119 V131 I133 M156 H241 L245 Y265 P37231 GPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 5jk5 A 2.07 BS01 FE A 1 H273 H278 E318 H259 H264 E304 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVLEMGSDLTSDHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDN 5jk5 A 2.07 BS02 PIN A 1 T226 R249 P285 D289 R388 T212 R235 P271 D275 R374 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVLEMGSDLTSDHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDN 5jk5 A 2.07 BS03 HBI A 1 V233 G235 L236 L237 F242 L243 S310 Y313 V219 G221 L222 L223 F228 L229 S296 Y299 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVLEMGSDLTSDHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDN 5jk5 A 2.07 BS04 PIN B 1 K58 N403 Y405 K44 N389 Y391 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVLEMGSDLTSDHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDN 5jk5 B 2.07 BS01 PIN A 1 N403 Y405 N379 Y381 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDNK 5jk5 B 2.07 BS02 FE B 1 H273 H278 E318 H249 H254 E294 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDNK 5jk5 B 2.07 BS03 PIN B 1 T226 P285 D289 K384 R388 T202 P261 D265 K360 R364 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDNK 5jk5 B 2.07 BS04 HBI B 1 V233 G235 L236 L237 A239 F242 L243 S310 Y313 V209 G211 L212 L213 A215 F218 L219 S286 Y289 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDNK 5jk6 A 2.07 BS01 PIN A 1 T226 R249 P285 D289 R388 T212 R235 P271 D275 R374 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVLEMGSDLTSDHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDN 5jk6 A 2.07 BS02 FE A 1 H273 H278 E318 H259 H264 E304 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVLEMGSDLTSDHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDN 5jk6 A 2.07 BS03 PIN B 1 K58 N403 Y405 K44 N389 Y391 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKVLEMGSDLTSDHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDN 5jk6 B 2.07 BS01 PIN A 1 N403 Y405 T406 N377 Y379 T380 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDNK 5jk6 B 2.07 BS02 PIN B 1 C225 T226 R249 P285 D289 K384 R388 C199 T200 R223 P259 D263 K358 R362 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDNK 5jk6 B 2.07 BS03 FE B 1 H273 H278 E318 H247 H252 E292 1.14.16.1,1.14.16.4 Q54XS1 QSYHSSIFFSISKGSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDYDFFLDLEYPTENNKEVEKVIKDLEEKGVKATTLQESSNQTYAPWFPRKISDLDLFANKPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQGLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDEDIQLLSTCYWFTVEFGLCKEGDTIRAYGAGILSSTGEMEHFLTDKAKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDNK 5jkv A 2.75 BS01 HEM A 1 M107 R115 I132 I133 W141 R145 L152 A306 S314 M364 V370 V373 R375 F430 G431 R435 G436 C437 M446 M447 M63 R71 I88 I89 W97 R101 L108 A262 S270 M320 V326 V329 R331 F386 G387 R391 G392 C393 M402 M403 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5jkv A 2.75 BS02 ASD A 1 R115 I133 W224 A306 D309 T310 V370 L372 M374 L477 R71 I89 W180 A262 D265 T266 V326 L328 M330 L433 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5jkw A 3.00 BS01 HEM A 1 M107 R115 I132 W141 R145 L152 M303 A306 T310 S314 M364 V370 V373 R375 F430 R435 G436 C437 M446 M447 M63 R71 I88 W97 R101 L108 M259 A262 T266 S270 M320 V326 V329 R331 F386 R391 G392 C393 M402 M403 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5jkw A 3.00 BS02 TES A 1 R115 I133 F134 W224 A306 D309 T310 V370 L372 V373 M374 L477 R71 I89 F90 W180 A262 D265 T266 V326 L328 V329 M330 L433 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5jl6 A 3.00 BS01 HEM A 1 M107 R115 I132 W141 R145 L152 M303 A306 T310 S314 M364 V370 V373 R375 F430 R435 G436 C437 M446 M447 M63 R71 I88 W97 R101 L108 M259 A262 T266 S270 M320 V326 V329 R331 F386 R391 G392 C393 M402 M403 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5jl6 A 3.00 BS02 ASD A 1 R115 I133 W224 A306 D309 T310 V370 L372 M374 L477 R71 I89 W180 A262 D265 T266 V326 L328 M330 L433 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5jl7 A 3.10 BS01 HEM A 1 M107 R115 I132 W141 R145 L152 M303 A306 T310 S314 M364 V370 V373 R375 F430 R435 G436 C437 A438 G439 M446 M447 M63 R71 I88 W97 R101 L108 M259 A262 T266 S270 M320 V326 V329 R331 F386 R391 G392 C393 A394 G395 M402 M403 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5jl7 A 3.10 BS02 ASD A 1 R115 I133 W224 I305 A306 D309 T310 V370 L372 M374 L477 R71 I89 W180 I261 A262 D265 T266 V326 L328 M330 L433 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5jl9 A 3.10 BS01 HEM A 1 M107 R115 I132 I133 W141 R145 L152 A306 T310 S314 M364 V373 R375 P429 F430 R435 G436 C437 M446 M447 M63 R71 I88 I89 W97 R101 L108 A262 T266 S270 M320 V329 R331 P385 F386 R391 G392 C393 M402 M403 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5jl9 A 3.10 BS02 ASD A 1 R115 I133 W224 A306 D309 T310 V370 L372 V373 M374 L477 R71 I89 W180 A262 D265 T266 V326 L328 V329 M330 L433 1.14.14.14 P11511 SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRN 5ju7 A 2.05 BS01 ZN A 1 E30 E74 E30 E74 P23890 AQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMVPVIWY 5ju7 A 2.05 BS02 ZN A 2 E30 E74 E30 E74 P23890 AQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMVPVIWY 5ju7 A 2.05 BS03 ZN A 3 Q42 H43 E46 Q42 H43 E46 P23890 AQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMVPVIWY 5ju7 A 2.05 BS04 ZN A 4 H43 E46 H43 E46 P23890 AQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMVPVIWY 5k4k A 1.76 BS01 ZN A 1 H120 H122 H189 H78 H80 H147 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k A 1.76 BS02 ZN A 2 D124 C208 H250 D82 C166 H208 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k A 1.76 BS03 MG A 1 E152 E223 E110 E181 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k A 1.76 BS04 SV7 A 1 L65 H120 H122 D124 H189 H250 L23 H78 H80 D82 H147 H208 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k A 1.76 BS05 NPO A 1 A99 L102 A131 A134 A135 A57 L60 A89 A92 A93 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k K 1.76 BS01 NPO K 1 A99 L102 A131 A134 A135 A57 L60 A89 A92 A93 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k K 1.76 BS02 ZN K 1 H120 H122 H189 H78 H80 H147 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k K 1.76 BS03 ZN K 2 D124 C208 H250 D82 C166 H208 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k K 1.76 BS04 MG K 1 E152 E223 E110 E181 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k K 1.76 BS05 SV7 K 1 R52 Y64 R10 Y22 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4k K 1.76 BS06 SV7 K 2 H120 H122 D124 H189 H250 H78 H80 D82 H147 H208 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4m A 1.98 BS01 ZN A 1 H120 H122 H189 H78 H80 H147 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4m A 1.98 BS02 ZN A 2 D124 C208 H250 D82 C166 H208 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4m A 1.98 BS03 MG A 1 E152 E223 E110 E181 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4m A 1.98 BS04 NPO A 1 A96 A99 A54 A57 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4m A 1.98 BS05 SV7 A 1 M67 V73 H120 H122 D124 H189 C208 H250 M25 V31 H78 H80 D82 H147 C166 H208 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4n A 1.68 BS01 SV7 A 1 L65 M67 H120 H122 D124 H189 H250 L23 M25 H78 H80 D82 H147 H208 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4n A 1.68 BS02 6QV A 1 T62 Y64 A74 N76 F251 A252 T20 Y22 A32 N34 F209 A210 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4n A 1.68 BS03 MG A 1 E152 E223 E110 E181 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4n A 1.68 BS04 ZN A 1 H120 H122 H189 H78 H80 H147 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5k4n A 1.68 BS05 ZN A 2 D124 C208 H250 D82 C166 H208 3.5.2.6 C7C422 DQRFGDPVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLMVDTAGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLGNLDEADTEHYAASVRAFGAAFPKASMIVMSHFAPDSRAAITHTARMADKLR 5khp A 2.65 BS01 ZR A 1 Y106 K125 Y102 K121 P80188 SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5khp A 2.65 BS02 7K9 A 1 K125 Y132 K134 K121 Y128 K130 P80188 SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5khp B 2.65 BS01 ZR B 1 K125 K134 K120 K129 P80188 DLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCI 5khp B 2.65 BS02 7K9 B 1 A40 K125 Y132 F133 K134 A35 K120 Y127 F128 K129 P80188 DLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCI 5khp C 2.65 BS01 ZR C 1 Y106 K125 Y102 K121 P80188 SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5khp C 2.65 BS02 7K9 C 1 K125 Y132 K134 K121 Y128 K130 P80188 SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5kic A 2.70 BS01 4OL A 1 A40 I41 Y52 S68 W79 R81 Y106 F123 K125 Y132 F133 K134 A36 I37 Y48 S64 W75 R77 Y102 F119 K121 Y128 F129 K130 P80188 SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5kic B 2.70 BS01 4OL B 1 A40 I41 Y52 S68 W79 R81 Y100 Y106 F123 K125 Y132 F133 K134 A38 I39 Y50 S66 W77 R79 Y98 Y104 F121 K123 Y130 F131 K132 P80188 STSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5kic C 2.70 BS01 4OL C 1 A40 I41 Y52 S68 W79 R81 Y100 Y106 F123 K125 Y132 F133 K134 A38 I39 Y50 S66 W77 R79 Y98 Y104 F121 K123 Y130 F131 K132 P80188 STSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5kid A 2.15 BS01 7K9 A 1 Y106 F123 K125 Y132 K134 Y102 F119 K121 Y128 K130 P80188 SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5kid B 2.15 BS01 7K9 B 1 Y106 F123 K125 Y132 F133 K134 Y98 F115 K117 Y124 F125 K126 P80188 SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILRPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5kid C 2.15 BS01 7K9 C 1 A40 Y106 F123 K125 Y132 F133 K134 A37 Y103 F120 K122 Y129 F130 K131 P80188 TSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 5kik A 2.20 BS01 FE A 1 H305 H307 E377 D403 H294 H296 E366 D392 F2RB80 27668828 HMRYSLRQDIAVEPVIAGWYGWSYLLPPQTLARFVHNRFNRIVESYLDDPQVHAAAVRQRRMHGGPWIHAHEHRDAIEAWYRETAPRRERLDELFEAVRRLEEDILPRHHGECLDPVYQELPAALAGRVEVFYGRDNRTADYRFVEPLMYASEYYDESWQQVRFRPVTEDAREFALTTPMLEYGPEQLLVNVPLNSPLLDAVFRGGLTGTELDDLAARFGLDGERAARFASYFEPTPEEDVLEYVGHACVFARHRGTTFLVDPVLSYSGYPGGAENRFTFADLPERIDHLLITHNHQDHMLFETLLRIRHRVGRVLVPKSTNASLVDPGLGGILRRLGFTDVVEVDDLETLSCGSAEVVALPFLGEHGDLRIRSKTGWLIRFGERSVLFAADSTNISPTMYTKVAEVIGPVDTVFIGMESIGAAASWIYGPLYGEPLDRRTDQSRRLNGSNFPQAREIVDALEPDEVYVYAMGLEPWMGVVMAVDYDESHPAIVDSDLLVRHVQDKGGTAERLHLRRTLRL 5kik A 2.20 BS02 FE A 2 H258 D309 H310 D403 H247 D298 H299 D392 F2RB80 27668828 HMRYSLRQDIAVEPVIAGWYGWSYLLPPQTLARFVHNRFNRIVESYLDDPQVHAAAVRQRRMHGGPWIHAHEHRDAIEAWYRETAPRRERLDELFEAVRRLEEDILPRHHGECLDPVYQELPAALAGRVEVFYGRDNRTADYRFVEPLMYASEYYDESWQQVRFRPVTEDAREFALTTPMLEYGPEQLLVNVPLNSPLLDAVFRGGLTGTELDDLAARFGLDGERAARFASYFEPTPEEDVLEYVGHACVFARHRGTTFLVDPVLSYSGYPGGAENRFTFADLPERIDHLLITHNHQDHMLFETLLRIRHRVGRVLVPKSTNASLVDPGLGGILRRLGFTDVVEVDDLETLSCGSAEVVALPFLGEHGDLRIRSKTGWLIRFGERSVLFAADSTNISPTMYTKVAEVIGPVDTVFIGMESIGAAASWIYGPLYGEPLDRRTDQSRRLNGSNFPQAREIVDALEPDEVYVYAMGLEPWMGVVMAVDYDESHPAIVDSDLLVRHVQDKGGTAERLHLRRTLRL 5kil A 2.72 BS01 FEO A 1 H258 H305 H307 D309 H310 D377 D403 H244 H291 H293 D295 H296 D363 D389 F2RB80 27668828 RYSLRQDIAVEPVIAGWYGWSYLLPPQTLARFVHNRFNRIVESYLDDPQVHAAAVRQRRMHGGPWIHAHEHRDAIEAWYRETAPRRERLDELFEAVRRLEEDILPRHHGECLDPVYQELPAALAGRVEVFYGRDNRTADYRFVEPLMYASEYYDESWQQVRFRPVTEDAREFALTTPMLEYGPEQLLVNVPLNSPLLDAVFRGGLTGTELDDLAARFGLDGERAARFASYFEPTPEDVLEYVGHACVFARHRGTTFLVDPVLSYSGYPGGAENRFTFADLPERIDHLLITHNHQDHMLFETLLRIRHRVGRVLVPKSTNASLVDPGLGGILRRLGFTDVVEVDDLETLSCGSAEVVALPFLGDHGDLRIRSKTGWLIRFGERSVLFAADSTNISPTMYTKVAEVIGPVDTVFIGMESIGAAASWIYGPLYGEPLDRRTDQSRRLNGSNFPQAREIVDALEPDEVYVYAMGLEPWMGVVMPAIVDSDLLVRHVQDKGGTAERLHLRRTLRL 5kq0 A 1.80 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 F261 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 F226 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPDSNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq0 A 1.80 BS02 OXY A 1 R108 W111 H112 D141 R73 W76 H77 D106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPDSNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq0 B 1.80 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPDSNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq0 B 1.80 BS02 OXY B 1 R108 W111 H112 D141 R73 W76 H77 D106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPDSNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq2 A 1.90 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPDGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq2 A 1.90 BS02 OXY A 1 R108 W111 H112 R73 W76 H77 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPDGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq2 B 1.90 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPDGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq2 B 1.90 BS02 OXY B 1 R108 W111 H112 D141 R73 W76 H77 D106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPDGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq3 A 1.85 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq3 A 1.85 BS02 OXY A 1 R108 W111 H112 A141 R73 W76 H77 A106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq3 B 1.85 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq3 B 1.85 BS02 OXY B 1 R108 W111 H112 A141 R73 W76 H77 A106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq6 A 1.62 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 F261 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 F226 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGDHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq6 A 1.62 BS02 OXY A 1 R108 W111 H112 D141 R73 W76 H77 D106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGDHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq6 B 1.62 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 P241 F261 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 F226 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGDHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kq6 B 1.62 BS02 OXY B 1 R108 W111 H112 D141 R73 W76 H77 D106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGDHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqh A 1.82 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 F261 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 F226 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNDGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqh A 1.82 BS02 OXY A 1 R108 W111 H112 R73 W76 H77 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNDGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqh B 1.82 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNDGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqh B 1.82 BS02 OXY B 1 R108 W111 H112 R73 W76 H77 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNDGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqi A 1.87 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 F416 W420 G70 L71 I73 R74 W77 V205 P207 L240 I241 G244 H245 G248 K249 T250 H251 T289 S290 W296 T354 F382 W386 1.11.1.21 Q3JNW6 28409923 NGTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGDEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqi A 1.87 BS02 OXY A 1 R108 W111 H112 R74 W77 H78 1.11.1.21 Q3JNW6 28409923 NGTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGDEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqi B 1.87 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 F416 W420 G70 L71 I73 R74 W77 V205 P207 L240 I241 G244 H245 G248 K249 T250 H251 T289 S290 W296 T354 F382 W386 1.11.1.21 Q3JNW6 28409923 NGTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGDEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqi B 1.87 BS02 OXY B 1 R108 W111 H112 D141 R74 W77 H78 D107 1.11.1.21 Q3JNW6 28409923 NGTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGDEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqk A 1.75 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 L326 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 L291 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqk A 1.75 BS02 OXY A 1 R108 W111 H112 D141 R73 W76 H77 D106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqk B 1.75 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5kqk B 1.75 BS02 OXY B 1 R108 W111 H112 R73 W76 H77 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5ksf A 1.75 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 F261 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 F226 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5ksf A 1.75 BS02 OXY A 1 R108 H112 A141 R73 H77 A106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5ksf B 1.75 BS01 HEM B 1 G104 L105 I107 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 F416 W420 G69 L70 I72 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5ksf B 1.75 BS02 OXY B 1 R108 H112 A141 R73 H77 A106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5ksk A 1.69 BS01 HEM A 1 G104 L105 I107 W111 V239 P241 F261 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 L326 W330 T388 F416 W420 G69 L70 I72 W76 V204 P206 F226 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 L291 W295 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5ksk A 1.69 BS02 OXY A 1 R108 W111 H112 D141 R73 W76 H77 D106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5ksk B 1.69 BS01 HEM B 1 G104 L105 I107 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5ksk B 1.69 BS02 OXY B 1 R108 W111 H112 D141 R73 W76 H77 D106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5lai G 2.50 BS01 MG G 1 T8 Y119 R122 A123 M125 T7 Y118 R121 A122 M124 3.4.25.1 P21243 27709817 GYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIAEQ 5lai I 2.50 BS01 MG I 1 A174 D177 S180 A174 D177 S180 3.4.25.1 P25451 27709817 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 5lai I 2.50 BS02 MG I 2 R27 A178 D204 R27 A178 D204 3.4.25.1 P25451 27709817 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 5lai J 2.50 BS01 MG J 1 Q118 D120 T124 Q118 D120 T124 3.4.25.1 P22141 27709817 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDF 5lai K 2.50 BS01 3K4 K 1 T2 D17 K33 G130 S131 G132 Y170 S171 T1 D16 K32 G129 S130 G131 Y169 S170 3.4.25.1 P30656 27709817 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5lai K 2.50 BS02 MG K 1 R19 A165 D168 A169 S171 R18 A164 D167 A168 S170 3.4.25.1 P30656 27709817 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5lai K 2.50 BS03 MG K 2 I82 N85 I81 N84 3.4.25.1 P30656 27709817 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5lai N 2.50 BS01 MG N 1 R19 I163 D166 S169 R19 I163 D166 S169 3.4.25.1 P38624 27709817 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL 5lai V 2.50 BS01 MG V 1 G162 I163 D166 S169 G162 I163 D166 S169 3.4.25.1 P25043 27709817 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 5lai Y 2.50 BS01 3K4 Y 1 T2 D17 K33 G130 S131 G132 Y170 S171 T1 D16 K32 G129 S130 G131 Y169 S170 3.4.25.1 P30656 27709817 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5lai Y 2.50 BS02 MG Y 1 R19 A165 D168 A169 S171 R18 A164 D167 A168 S170 3.4.25.1 P30656 27709817 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5lai Z 2.50 BS01 MG Z 1 T192 H195 I196 V198 T192 H195 I196 V198 3.4.25.1 P23724 27709817 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 5laj G 2.90 BS01 MG G 1 T8 Y119 R122 A123 M125 T7 Y118 R121 A122 M124 3.4.25.1 P21243 27709817 GYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIAEQ 5laj I 2.90 BS01 MG I 1 A174 D177 S180 D204 A174 D177 S180 D204 3.4.25.1 P25451 27709817 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 5laj I 2.90 BS02 MG I 2 R27 A178 D204 R27 A178 D204 3.4.25.1 P25451 27709817 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 5laj J 2.90 BS01 MG J 1 Q118 D120 T124 Q118 D120 T124 3.4.25.1 P22141 27709817 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDF 5laj K 2.90 BS01 MG K 1 A165 D168 A169 S171 A165 D168 A169 S171 3.4.25.1 P30656 27709817 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5laj N 2.90 BS01 MG N 1 R19 I163 D166 S169 R19 I163 D166 S169 3.4.25.1 P38624 27709817 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL 5laj V 2.90 BS01 MG V 1 I163 D166 L167 S169 I163 D166 L167 S169 3.4.25.1 P25043 27709817 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 5laj Y 2.90 BS01 MG Y 1 R19 A165 D168 A169 S171 R19 A165 D168 A169 S171 3.4.25.1 P30656 27709817 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5laj Z 2.90 BS01 MG Z 1 T192 H195 I196 V198 T192 H195 I196 V198 3.4.25.1 P23724 27709817 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 5lb7 A 1.50 BS01 III C 1 V504 Y574 V20 Y90 Q8BG40 LVDEDAMSQIRKGHDTMFVVLTSRHKNLDTVRAVWTTGDIKTSVDSAVAINDLSVVVDLLNIVNQKASLWKLDLCTTVLPQIEKLLQSKYESYVQTGCTSLKLILQRFLPLITDILAAPPSREERLHKCRLCFKQLKSISGLVKSKSGLSGRHGSAFRELHLLMAS 5lb7 B 1.50 BS01 III C 1 L18 L19 L18 L19 3.6.4.3 Q9WV86 MSLQMIVENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSVKDTHLRQKWQQVWQEINVEAKQVKDIMKTLESFKL 5lbh A 2.55 BS01 FE A 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh A 2.55 BS02 FE J 1 H24 H36 H24 H36 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh B 2.55 BS01 FE B 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh B 2.55 BS02 FE E 1 H24 H36 Y43 H24 H36 Y43 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh C 2.55 BS01 FE C 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh C 2.55 BS02 FE I 1 H24 H36 Q40 H24 H36 Q40 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh D 2.55 BS01 FE D 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh D 2.55 BS02 FE G 1 H24 H36 Y43 H24 H36 Y43 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh E 2.55 BS01 FE B 1 H24 H36 Y43 H24 H36 Y43 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh E 2.55 BS02 FE E 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh F 2.55 BS01 FE F 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh F 2.55 BS02 FE L 1 H24 H36 Y43 H24 H36 Y43 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh G 2.55 BS01 FE D 1 H24 H36 H24 H36 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh G 2.55 BS02 FE G 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh H 2.55 BS01 FE H 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh H 2.55 BS02 FE K 1 H24 Y43 H24 Y43 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh I 2.55 BS01 FE I 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh J 2.55 BS01 FE A 1 H24 H36 Y43 H24 H36 Y43 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh J 2.55 BS02 FE J 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh K 2.55 BS01 FE H 1 H24 H36 Y43 H24 H36 Y43 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh K 2.55 BS02 FE K 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh L 2.55 BS01 FE F 1 H24 H36 Y43 H24 H36 Y43 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lbh L 2.55 BS02 FE L 1 D51 E55 D51 E55 28074932 KVVELLKQIQADASVFYVKVHNFHWNVKGMDFHPTHKATQEIYEQFADVFDDVAERVLQLGEMPYVTLADMLKAAKIKEESKTSFCSKEIAQAVLADYEYFLKLFTELSAQADSQGDKVSAAYADDKVGELQKAIWMLKSQLA 5lyq A 2.17 BS01 III B 1 F277 V280 K284 L294 V298 L301 R302 T449 F450 E453 E456 A457 P458 F31 V34 K38 L48 V52 L55 R56 T203 F204 E207 E210 A211 P212 P19793 28407400 DMPVERILEAELAVEPDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 5lyq A 2.17 BS02 7BE A 1 I268 A271 A272 Q275 N306 L309 I310 F313 R316 I324 L326 A327 V342 I345 F346 C432 H435 L436 F439 I22 A25 A26 Q29 N60 L63 I64 F67 R70 I78 L80 A81 V96 I99 F100 C186 H189 L190 F193 P19793 28407400 DMPVERILEAELAVEPDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 5mmn A 1.90 BS01 O54 A 1 V43 N46 A47 E50 V71 D73 R76 G77 I78 P79 I94 V37 N40 A41 E44 V65 D67 R70 G71 I72 P73 I88 5.99.1.3 P0AES7 28406299 SSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYE 5mmo A 1.81 BS01 9JG A 1 V43 N46 A47 E50 V71 D73 R76 G77 I78 P79 I94 R136 T165 V37 N40 A41 E44 V65 D67 R70 G71 I72 P73 I88 R123 T152 5.99.1.3 P0AES7 28406299 SSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYE 5mmp A 2.05 BS01 G3Z A 1 N46 A47 E50 V71 D73 R76 G77 I78 P79 I94 V120 R136 T165 N37 A38 E41 V62 D64 R67 G68 I69 P70 I85 V92 R108 T137 5.99.1.3 P0AES7 28406299 IKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYE 5mul A 1.39 BS01 BDP A 1 P148 L149 T150 D151 G152 V202 D203 G206 E389 K392 K393 P114 L115 T116 D117 G118 V168 D169 G172 E350 K353 K354 Q8A1H5 28396425 LRQQKLVEVAKGYSLVTHGDEQYISYYDADGYLVLGKRKLNSKQWTLHRTQYRGAHNIISIMVDGEGYLHVSFDHHGHKLNYCRSIAPGSLELGDKMPMTGVDEGNVTYPEFYPLTDGDLLFVYRSGSSGRGNLVMNRYSLKDHKWARVQDVLIDGEDKRNAYWQLYVDEKGTIHLSWVWRETWQVETNHDLCYARSFDNGVTWYKSDGEQYKLPITASNAEYACRIPQNSELINQTSMSADAGGNPYIATYWRSSDSEVPQYRIVWNDGKTWHNRQVTDRKTPFTLKMIPVARPRIVVEDGEIFYIFRDEERGSRVSMAHTADVANGKWIVTDLTDFSVDAWEPSHDTELWKKQRKLNLFVQHTCPQMIYVLEANTN 5my1 Y 7.60 BS01 ZN Y 1 C70 C72 C85 C88 C70 C72 C85 C88 2.7.7.6 P0A8T7 MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 5n07 A 1.95 BS01 SF4 A 1 V91 C93 C99 L101 R102 C105 L107 R108 V84 C86 C92 L94 R95 C98 L100 R101 Q9L132 RLTKFTDLALRSLMRLAVVRDGDEPLATREVAEVVGVPYTHAAKAITRLQHLGVVEAGLTLTDLGRRVSVGWLVRELEGEAEVVDCEGDNPCPLRGACRLRRALRDAQEAFYAALDPLTVTDLVAAPTGPVLLGLTD 5n2i A 1.80 BS01 NAP A 1 G26 T28 G29 D30 Q31 S50 R51 R55 A87 V88 P89 G92 C112 V113 N114 F150 H151 V153 A155 G19 T21 G22 D23 Q24 S43 R44 R48 A80 V81 P82 G85 C105 V106 N107 F143 H144 V146 A148 1.6.99.- Q47RA9 28411200 KSSPHDLPDVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAGAAEAGDVVIVAVPWDGHRALLESLKDVLAGKIVVDCVNPLGFDKRGAYALPVEEGSAAEQAAAILPDSRVVAAFHHVSAVLLLDPEVEKVDLDVLVLGDDREATDVVRALAARIPGVRGVYGGRLRNAHQVEAFTANLISINRRYKAHAGIRITDI 5n2i B 1.80 BS01 NAP B 1 G26 T28 G29 D30 Q31 S50 R51 R55 A87 V88 P89 G92 C112 V113 N114 F150 H151 V153 A155 G17 T19 G20 D21 Q22 S41 R42 R46 A78 V79 P80 G83 C103 V104 N105 F141 H142 V144 A146 1.6.99.- Q47RA9 28411200 SPHDLPDVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAGAAEAGDVVIVAVPWDGHRALLESLKDVLAGKIVVDCVNPLGFDKRGAYALPVEEGSAAEQAAAILPDSRVVAAFHHVSAVLLLDPEVEKVDLDVLVLGDDREATDVVRALAARIPGVRGVYGGRLRNAHQVEAFTANLISINRRYKAHAGIRITDI 5n2i C 1.80 BS01 NAP C 1 G26 T28 G29 D30 Q31 S50 R51 R55 A87 V88 P89 G92 C112 V113 N114 F150 H151 V153 A155 G17 T19 G20 D21 Q22 S41 R42 R46 A78 V79 P80 G83 C103 V104 N105 F141 H142 V144 A146 1.6.99.- Q47RA9 28411200 SPHDLPDVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAGAAEAGDVVIVAVPWDGHRALLESLKDVLAGKIVVDCVNPLGFDKRGAYALPVEEGSAAEQAAAILPDSRVVAAFHHVSAVLLLDPEVEKVDLDVLVLGDDREATDVVRALAARIPGVRGVYGGRLRNAHQVEAFTANLISINRRYKAHAGIRITDI 5n2i D 1.80 BS01 NAP D 1 G26 T28 G29 D30 Q31 S50 R51 R55 A87 V88 P89 G92 C112 V113 N114 F150 H151 V153 A155 G16 T18 G19 D20 Q21 S40 R41 R45 A77 V78 P79 G82 C102 V103 N104 F140 H141 V143 A145 1.6.99.- Q47RA9 28411200 PHDLPDVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAGAAEAGDVVIVAVPWDGHRALLESLKDVLAGKIVVDCVNPLGFDKRGAYALPVEEGSAAEQAAAILPDSRVVAAFHHVSAVLLLDPEVEKVDLDVLVLGDDREATDVVRALAARIPGVRGVYGGRLRNAHQVEAFTANLISINRRYKAHAGIRITDI 5n7o A 2.30 BS01 69Y A 1 E70 M74 M77 A96 V97 W100 I113 F126 A130 S134 T138 L141 L167 D168 E60 M64 M67 A86 V87 W90 I103 F116 A120 S124 T128 L131 L157 D158 O53623 28416386 RSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG 5n7o B 2.30 BS01 69Y B 1 E70 M74 M77 I93 A96 V97 W100 I113 F126 A130 S134 T138 L141 L167 D168 E60 M64 M67 I83 A86 V87 W90 I103 F116 A120 S124 T128 L131 L157 D158 O53623 28416386 RSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG 5nhz A 1.85 BS01 ZN A 1 H116 H118 H196 H83 H85 H148 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5nhz A 1.85 BS02 ZN A 2 D120 C221 H263 D87 C167 H209 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5nhz A 1.85 BS03 8XZ A 1 F61 Y67 W87 H118 D119 D120 H196 C221 R228 N233 H263 F31 Y36 W56 H85 D86 D87 H148 C167 R174 N179 H209 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5nhz B 1.85 BS01 ZN B 1 V134 A135 T136 T169 V100 A101 T102 T121 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5nhz B 1.85 BS02 ZN B 2 H116 H118 H196 H83 H85 H148 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5nhz B 1.85 BS03 ZN B 3 D120 R121 C221 H263 D87 R88 C167 H209 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5nhz B 1.85 BS04 8XZ B 1 F61 Y67 W87 H118 D119 D120 H196 C221 R228 G232 N233 H263 F31 Y36 W56 H85 D86 D87 H148 C167 R174 G178 N179 H209 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5ni0 A 1.67 BS01 ZN A 1 H116 H118 H196 H83 H85 H148 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5ni0 A 1.67 BS02 ZN A 2 D120 C221 H263 D87 C167 H209 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5ni0 A 1.67 BS03 8XW A 1 F61 Y67 W87 H118 D120 H196 C221 R228 N233 H263 F31 Y36 W56 H85 D87 H148 C167 R174 N179 H209 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5ni0 E 1.67 BS01 ZN E 1 H116 H118 H196 H83 H85 H148 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHT 5ni0 E 1.67 BS02 ZN E 2 D120 R121 C221 H263 D87 R88 C167 H209 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHT 5ni0 E 1.67 BS03 8XW E 1 F61 Y67 W87 H118 D119 D120 H196 C221 R228 G232 N233 H263 F31 Y36 W56 H85 D86 D87 H148 C167 R174 G178 N179 H209 Q9K2N0 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHT 5nkq A 2.17 BS01 NA A 1 G77 G78 T80 T81 G76 G77 T79 T80 Q7VYU0 26344196 LTYAPLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq A 2.17 BS02 F A 1 N43 F85 Y104 S108 N42 F84 Y103 S107 Q7VYU0 26344196 LTYAPLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq A 2.17 BS03 F B 1 N43 S112 N42 S111 Q7VYU0 26344196 LTYAPLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq B 2.17 BS01 NA A 1 G77 G78 T80 T81 G73 G74 T76 T77 Q7VYU0 26344196 APLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq B 2.17 BS02 F A 2 N43 G47 S112 N39 G43 S108 Q7VYU0 26344196 APLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq B 2.17 BS03 F B 2 L40 N43 Y104 S108 L36 N39 Y100 S104 Q7VYU0 26344196 APLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq C 2.17 BS01 NA C 1 G77 G78 T80 T81 G75 G76 T78 T79 Q7VYU0 26344196 TYAPLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq C 2.17 BS02 F C 1 N43 G47 S112 N41 G45 S110 Q7VYU0 26344196 TYAPLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq C 2.17 BS03 F C 2 L40 N43 Y104 S108 L38 N41 Y102 S106 Q7VYU0 26344196 TYAPLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq D 2.17 BS01 NA C 1 G77 G78 T80 T81 G73 G74 T76 T77 Q7VYU0 26344196 APLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq D 2.17 BS02 F C 3 N43 G47 S112 N39 G43 S108 Q7VYU0 26344196 APLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nkq D 2.17 BS03 F D 1 L40 N43 Y104 S108 L36 N39 Y100 S104 Q7VYU0 26344196 APLNFIAIGIGATLGAWLRWVLGLKLNGAGWPWGTLTANLVGGYLIGVMVALIASHPEWPAWIRLAAVTGFLGGLTTFSTFSAETVDMLCRGVYATAAAYAGASLAGSLAMTGLGLATVRLLLR 5nl4 B 1.32 BS01 ZN B 1 K6 H68 K6 H68 P0CG48 MQIFVKTLTGKTITLVVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR 5nl5 B 1.96 BS01 ZN B 1 K6 H68 K6 H68 P0CG47 MQIFVKTLTGKTITLVVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR 5nlj B 1.53 BS01 ZN B 1 K11 E34 K11 E34 P0CG47 MQIFVKTLTGKTITLVVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVL 5nnx A 3.29 BS01 NUC C 1 K88 Q89 S92 Q95 R100 K58 Q59 S62 Q65 R70 P28347 AEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRD 5nnx A 3.29 BS02 NUC F 1 I58 G68 R69 N70 E71 R87 K88 Q95 I28 G38 R39 N40 E41 R57 K58 Q65 P28347 AEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRD 5t8e A 2.71 BS01 77U A 1 L704 N705 L707 Q711 M742 M745 M749 R752 F764 M780 L873 T877 L34 N35 L37 Q41 M72 M75 M79 R82 F94 M110 L203 T207 P10275 28363748 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ 5t8j A 2.70 BS01 77T A 1 L704 L707 G708 Q711 M742 M745 R752 F764 M780 L873 T877 L34 L37 G38 Q41 M72 M75 R82 F94 M110 L203 T207 P10275 28363748 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ 5th4 A 1.47 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSGTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5th4 A 1.47 BS02 BEW A 1 H94 H96 H119 V121 T199 T200 W209 H91 H93 H116 V118 T195 T196 W205 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSGTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5th4 A 1.47 BS03 DMS A 1 G198 T200 P202 L203 L204 G194 T196 P198 L199 L200 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSGTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thi A 1.50 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSGTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thi A 1.50 BS02 0TR A 1 H94 H96 H119 V121 G198 T199 T200 H91 H93 H116 V118 G194 T195 T196 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSGTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thj A 1.50 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thj A 1.50 BS02 0TR A 1 H94 H96 H119 V121 L198 T199 T200 H91 H93 H116 V118 L194 T195 T196 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thj A 1.50 BS03 DMS A 1 S99 L100 D101 R227 S96 L97 D98 R223 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thj A 1.50 BS04 DMS A 2 Y7 D243 W245 P247 Y4 D239 W241 P243 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thj A 1.50 BS05 DMS A 3 K159 F176 T177 F179 K155 F172 T173 F175 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thj A 1.50 BS06 DMS A 4 D52 A54 N178 D180 D49 A51 N174 D176 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thj A 1.50 BS07 DMS A 5 Y7 G8 V242 D243 Y4 G5 V238 D239 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thn A 1.33 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5thn A 1.33 BS02 7CZ A 1 H94 H96 H119 V121 L198 T199 T200 W209 H91 H93 H116 V118 L194 T195 T196 W205 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ti0 A 1.42 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSGTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ti0 A 1.42 BS02 7CZ A 1 H94 H96 H119 T199 T200 W209 H91 H93 H116 T195 T196 W205 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSGTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ti0 A 1.42 BS03 DMS A 1 V135 L141 G198 T200 P202 L203 L204 V131 L137 G194 T196 P198 L199 L200 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSGTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ti0 A 1.42 BS04 DMS A 2 Y7 P13 D243 W245 P247 Y4 P10 D239 W241 P243 4.2.1.1 P00918 28389830 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSGTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5tid A 1.20 BS01 OCA A 1 D9 S10 L11 G44 G72 N73 L76 R108 P110 H157 D10 S11 L12 G45 G73 N74 L77 R109 P111 H158 3.1.2.-,3.1.1.5 P0ADA1 GMDTLLILGDSLSAGYRMSASAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLRGFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVPLLPFFLEEVKKKPQWMQDDGIHPNRDAQPFIADWMAKQLQPL 5tie A 1.15 BS01 OCA A 1 D9 S10 L11 G44 G72 N73 L76 R108 L109 H157 D10 S11 L12 G45 G73 N74 L77 R109 L110 H158 3.1.2.-,3.1.1.5 P0ADA1 GMDTLLILGDSLSAGYRMSASAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLRGFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVPLLPFFLEEVKKKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNH 5tif A 0.97 BS01 OCA A 1 D9 S10 L11 G44 G72 N73 L76 R108 L109 H157 D10 S11 L12 G45 G73 N74 L77 R109 L110 H158 3.1.2.-,3.1.1.5 P0ADA1 GMDTLLILGDSLSAGYRMSASAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLRGFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVPLLPFFLEEVKKKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHD 5tkv A 2.70 BS01 GLN A 1 G351 G352 F353 C379 L380 Q383 E403 R468 H469 R470 Y471 H515 G351 G352 F353 C379 L380 Q383 E403 R457 H458 R459 Y460 H504 6.3.4.2 P0A7E5 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNAPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQ 5tkv A 2.70 BS02 CTP B 1 S14 D147 I148 E149 S14 D147 I148 E149 6.3.4.2 P0A7E5 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNAPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQ 5tkv A 2.70 BS03 CTP B 2 K187 T188 K189 Q192 K223 F227 K187 T188 K189 Q192 K223 F227 6.3.4.2 P0A7E5 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNAPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQ 5tkv B 2.70 BS01 CTP B 1 K187 T188 K189 Q192 K223 F227 K187 T188 K189 Q192 K223 F227 6.3.4.2 P0A7E5 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNAPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5tkv B 2.70 BS02 CTP B 3 S14 D147 I148 E149 S14 D147 I148 E149 6.3.4.2 P0A7E5 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNAPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5tkv B 2.70 BS03 GLN B 1 G351 G352 F353 C379 L380 Q383 E403 H469 R470 Y471 G351 G352 F353 C379 L380 Q383 E403 H460 R461 Y462 6.3.4.2 P0A7E5 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNAPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5tnt A 1.40 BS01 7GQ A 1 Y99 H147 F174 D189 S190 C191 Q192 S195 I213 W215 G216 E217 C220 G226 Y86 H135 F162 D179 S180 C181 Q182 S185 I203 W205 G206 E207 C209 G216 3.4.21.22 P00740 28408226 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGASALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT 5tqm A 2.90 BS01 NAP A 1 G38 G41 Y42 I43 R63 D89 L90 T109 A110 S111 P112 V113 T147 S148 S149 Y183 K187 P210 V211 V213 S225 G8 G11 Y12 I13 R33 D59 L60 T79 A80 S81 P82 V83 T117 S118 S119 Y153 K157 P180 V181 V183 S195 C5YLL4 GQTVCVTGAAGYIASWLVKMLLEKGYTVKGTVRNPDDPKNAHLKALDGAAERLILCKADLLDYDAICRAVQGCQGVFHTASPVTDDPEQMVEPAVRGTEYVINAAAEAGTVRRVVFTSSIGAVTMDPSRGPDVVVDESCWSDLEFCKKTRNWYCYGKAVAEQAAWDAARQRGVDLVVVNPVLVVGPLLQPTVNASIAHVLKYLDGSARTFANAVQAYVDVRDVADAHLRVFESPAASGRYLCAERVLHREDVVRILAKLFPEYPVPTRCSDEVNPRKQPYKFSNQKLRDLGLEFRPVSQSLYDTVKNLQEKGHLP 5tqm B 2.90 BS01 NAP B 1 G38 G41 Y42 I43 R63 A88 D89 L90 T109 A110 S111 V113 T147 S148 S149 Y183 K187 P210 V211 V213 S225 G8 G11 Y12 I13 R33 A58 D59 L60 T79 A80 S81 V83 T117 S118 S119 Y153 K157 P180 V181 V183 S195 C5YLL4 GQTVCVTGAAGYIASWLVKMLLEKGYTVKGTVRNPDDPKNAHLKALDGAAERLILCKADLLDYDAICRAVQGCQGVFHTASPVTDDPEQMVEPAVRGTEYVINAAAEAGTVRRVVFTSSIGAVTMDPSRGPDVVVDESCWSDLEFCKKTRNWYCYGKAVAEQAAWDAARQRGVDLVVVNPVLVVGPLLQPTVNASIAHVLKYLDGSARTFANAVQAYVDVRDVADAHLRVFESPAASGRYLCAERVLHREDVVRILAKLFPEYPVPTRCSDEVNPRKQPYKFSNQKLRDLGLEFRPVSQSLYDTVKNLQEKGHLP 5ts5 A 2.30 BS01 FAD A 1 V39 G40 G42 M43 S44 L62 E63 A64 G70 R71 V72 G87 P88 M89 R90 A259 R260 V261 C293 T294 T295 A298 Y372 W420 G429 I430 G456 E457 G464 W465 I466 T469 V38 G39 G41 M42 S43 L61 E62 A63 G69 R70 V71 G86 P87 M88 R89 A258 R259 V260 C292 T293 T294 A297 Y371 W419 G428 I429 G455 E456 G463 W464 I465 T468 1.4.3.2 A0A0S1LJ33 28137621 DDRNPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 A 2.30 BS02 ZN A 1 H314 H440 H313 H439 1.4.3.2 A0A0S1LJ33 28137621 DDRNPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 B 2.30 BS01 ZN A 2 H314 H440 H311 H437 1.4.3.2 A0A0S1LJ33 28137621 RNPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 B 2.30 BS02 FAD B 1 V39 G40 G42 S44 L62 E63 A64 G70 R71 V72 G87 P88 M89 R90 A259 R260 V261 C293 T294 A298 Y372 W420 Y425 G429 I430 G456 E457 G464 W465 I466 T469 V36 G37 G39 S41 L59 E60 A61 G67 R68 V69 G84 P85 M86 R87 A256 R257 V258 C290 T291 A295 Y369 W417 Y422 G426 I427 G453 E454 G461 W462 I463 T466 1.4.3.2 A0A0S1LJ33 28137621 RNPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 B 2.30 BS03 ZN B 1 K334 E337 K331 E334 1.4.3.2 A0A0S1LJ33 28137621 RNPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 B 2.30 BS04 ZN B 2 E8 D225 E5 D222 1.4.3.2 A0A0S1LJ33 28137621 RNPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 C 2.30 BS01 FAD C 1 V39 G40 G42 S44 L62 E63 A64 G70 R71 V72 G87 P88 M89 R90 L91 A259 R260 V261 C293 T294 A298 Y372 W420 Y425 G429 I430 G456 E457 G464 W465 I466 T469 V35 G36 G38 S40 L58 E59 A60 G66 R67 V68 G83 P84 M85 R86 L87 A255 R256 V257 C289 T290 A294 Y368 W416 Y421 G425 I426 G452 E453 G460 W461 I462 T465 1.4.3.2 A0A0S1LJ33 28137621 NPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 C 2.30 BS02 ZN C 1 H314 H440 H310 H436 1.4.3.2 A0A0S1LJ33 28137621 NPLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 D 2.30 BS01 ZN C 2 H314 H440 H309 H435 1.4.3.2 A0A0S1LJ33 28137621 PLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 D 2.30 BS02 FAD D 1 V39 G40 G42 M43 S44 L62 E63 A64 G70 R71 V72 G87 P88 M89 R90 A259 R260 V261 C293 T294 T295 A298 Y372 W420 Y425 G429 I430 G456 E457 G464 W465 I466 T469 V34 G35 G37 M38 S39 L57 E58 A59 G65 R66 V67 G82 P83 M84 R85 A254 R255 V256 C288 T289 T290 A293 Y367 W415 Y420 G424 I425 G451 E452 G459 W460 I461 T464 1.4.3.2 A0A0S1LJ33 28137621 PLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5ts5 D 2.30 BS03 ZN D 1 E93 E230 E88 E225 1.4.3.2 A0A0S1LJ33 28137621 PLEECFRETDYEEFLEIAKNGLSTTSNPKRVVIVGAGMSGLSAAYVLANAGHQVTVLEASERAGGRVKTYRNEKEGWYANLGPMRLPEKHRIVREYIRKFDLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEVGKSAGQLYEESLQKAVEELRRTNCSYMLNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVGGMDKLPTSMYQAIQEKVHLNARVIKIQQDVKEVTVTYQTSEKETLSVTADYVIVCTTSRAARRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSTTDLPSRFIYYPNHNFPNGVGVIIAYGIGDDANYFQALDFEDCGDIVINDLSLIHQLPKEEIQAICRPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLRAARDVNRAS 5txq A 1.90 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNDNLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5txq A 1.90 BS02 OXY A 1 R108 W111 H112 R73 W76 H77 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNDNLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5txq B 1.90 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G69 L70 I72 R73 W76 V204 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 L351 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNDNLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5txq B 1.90 BS02 OXY B 1 R108 W111 H112 R73 W76 H77 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNDNLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5u03 A 6.10 BS01 ATP A 1 G13 I14 G15 K16 G17 I18 D70 E146 R217 V247 I250 G13 I14 G15 K16 G17 I18 D70 E146 R217 V247 I250 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 A 6.10 BS02 UTP A 1 S12 K38 D40 P41 Y42 G148 G149 E155 S12 K38 D40 P41 Y42 G148 G149 E155 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 A 6.10 BS03 UTP B 1 K193 T194 K195 Q198 F233 K193 T194 K195 Q198 F233 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 B 6.10 BS01 UTP A 1 K193 T194 K195 Q198 F233 K193 T194 K195 Q198 F233 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 B 6.10 BS02 ATP B 1 G13 I14 G15 K16 G17 I18 D70 E146 R217 V247 I250 G13 I14 G15 K16 G17 I18 D70 E146 R217 V247 I250 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 B 6.10 BS03 UTP B 1 S12 K38 D40 P41 Y42 G148 G149 E155 S12 K38 D40 P41 Y42 G148 G149 E155 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 C 6.10 BS01 ATP C 1 G13 I14 G15 K16 G17 I18 D70 E146 R217 V247 I250 G13 I14 G15 K16 G17 I18 D70 E146 R217 V247 I250 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 C 6.10 BS02 UTP C 1 S12 K38 D40 P41 Y42 G148 G149 E155 S12 K38 D40 P41 Y42 G148 G149 E155 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 C 6.10 BS03 UTP D 1 K193 T194 K195 Q198 F233 K193 T194 K195 Q198 F233 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 D 6.10 BS01 UTP C 1 K193 T194 K195 Q198 F233 K193 T194 K195 Q198 F233 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 D 6.10 BS02 ATP D 1 G13 I14 G15 K16 G17 I18 D70 E146 R217 V247 I250 G13 I14 G15 K16 G17 I18 D70 E146 R217 V247 I250 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u03 D 6.10 BS03 UTP D 1 S12 K38 D40 P41 Y42 G148 G149 E155 S12 K38 D40 P41 Y42 G148 G149 E155 6.3.4.2 P17812 MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKALEHSALAINHKLEIKYIDSADLEPITSQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQAIAWARNQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPTTSHPVVVDMPEHNPGQMGGTMRLGKRRTLFQTKNSVMRKLYGDADYLEERHRHRFEVNPVWKKCLEEQGLKFVGQDVEGERMEIVELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSHYLQKGC 5u0l A 2.29 BS01 8YP A 1 K109 H154 L155 G158 H159 T224 E248 F446 S458 A459 K107 H152 L153 G156 H157 T222 E246 F444 S456 A457 1.2.1.71 A1U5W8 28389542 NLTGNVYIDGLWLPGHGAPFESVQPVTGETVWDGNAASLEDVDAAVREARKAFLAWRRKSLAERQAVIEAFGELLEANKEELAHQIGLETGKPLWESRTEVAAMMGKIPISVKAYNERTGHTESDVAGGHAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPGVAELTVRLWEKAGLPDGVINLVQGGSDTGKCLARHSLIDGLFFTGSSTVGHLLHEQFGGQPEKILALEMGGNNPLIVQNVSDLDGAVHHALQSAFLSAGQRCTCARRLLVPKGKKGDEFLARLVEVAARITVAEFDADPQPFMGSVISAEAANQLLKAQAAMLEKGATSLLEMKQLKPDTGLLSPGIVDATGIELEDQEFFGPLLTVYRYKGFDEALELANNTRYGLSAGILSDDRKLYNRLVEEVRAGIVNWNRPLTGASSAAPFGGVGASGNHRPSAYYAADYCAWPMASLEAGKSELPDSLAPGLNF 5u0m A 3.08 BS01 NAD A 1 F146 Y149 N150 L155 K173 P174 S175 E176 G209 T224 G225 S226 V229 E248 M249 G250 C282 E379 F381 F144 Y147 N148 L153 K171 P172 S173 E174 G207 T222 G223 S224 V227 E246 M247 G248 C280 E377 F379 1.2.1.71 A1U5W8 28389542 NLTGNVYIDGLWLPGHGAPFESVQPVTGETVWDGNAASLEDVDAAVREARKAFLAWRRKSLAERQAVIEAFGELLEANKEELAHQIGLETGKPLWESRTEVAAMMGKIPISVKAYNERTGHTESDVAGGHAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPGVAELTVRLWEKAGLPDGVINLVQGGSDTGKCLARHSLIDGLFFTGSSTVGHLLHEQFGGQPEKILALEMGGNNPLIVQNVSDLDGAVHHALQSAFLSAGQRCTCARRLLVPKGKKGDEFLARLVEVAARITVAEFDADPQPFMGSVISAEAANQLLKAQAAMLEKGATSLLEMKQLKPDTGLLSPGIVDATGIELEDQEFFGPLLTVYRYKGFDEALELANNTRYGLSAGILSDDRKLYNRLVEEVRAGIVNWNRPLTGASSAAPFGGVGASGNHRPSAYYAADYCAWPMASLEAGKSELPDSLAPGLNF 5u0m B 3.08 BS01 NAD B 1 F146 G147 P148 Y149 N150 L155 K173 P174 S175 E176 G209 T224 G225 S226 V229 E248 M249 G250 C282 E379 F381 F446 F143 G144 P145 Y146 N147 L152 K170 P171 S172 E173 G206 T221 G222 S223 V226 E245 M246 G247 C279 E376 F378 F443 1.2.1.71 A1U5W8 28389542 LTGNVYIDGLWLPGHGAPFESVQPVTGETVWDGNAASLEDVDAAVREARKAFLAWRRKSLAERQAVIEAFGELLEANKEELAHQIGLETGKPLWESRTEVAAMMGKIPISVKAYNERTGHTESDVAGGHAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPGVAELTVRLWEKAGLPDGVINLVQGGSDTGKCLARHSLIDGLFFTGSSTVGHLLHEQFGGQPEKILALEMGGNNPLIVQNVSDLDGAVHHALQSAFLSAGQRCTCARRLLVPKGKKGDEFLARLVEVAARITVAEFDADPQPFMGSVISAEAANQLLKAQAAMLEKGATSLLEMKQLKPDTGLLSPGIVDATGIELEDQEFFGPLLTVYRYKGFDEALELANNTRYGLSAGILSDDRKLYNRLVEEVRAGIVNWNRPLTGASSAAPFGGVGASGNHRPSAYYAADYCAWPMASLEAGKSELPDSLAPGLNF 5u2b A 2.22 BS01 6WV A 1 M343 L346 T347 A350 E353 L387 M388 L391 R394 M421 H524 L525 M528 M43 L46 T47 A50 E53 L87 M88 L91 R94 M121 H223 L224 M227 P03372 28306507 KRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCLSDLLLEMLDAHR 5u2b B 2.22 BS01 6WV B 1 L346 A350 E353 L387 M388 L391 R394 F404 M421 H524 L38 A42 E45 L79 M80 L83 R86 F96 M113 H204 P03372 28306507 NSLALSLTADQMVSALLDAEPPILYSEYDPTASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5u2b C 2.22 BS01 6WV C 1 M343 E353 L387 M388 L391 R394 F404 M421 H524 L525 M528 M44 E54 L88 M89 L92 R95 F105 M122 H222 L223 M226 P03372 28306507 RSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCVPLSDLLLEMLDAHRL 5u2b D 2.22 BS01 6WV D 1 E353 L387 M388 L391 R394 M421 H524 L525 E41 L75 M76 L79 R82 M109 H202 L203 P03372 28306507 NSLALSLTADQMVSALLDAEPPILYSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKVPLSDLLLEMLDAHRLH 5u2b E 2.22 BS01 6WV E 1 A350 E353 L387 M388 L391 R394 F404 M421 L428 H524 A41 E44 L78 M79 L82 R85 F95 M112 L119 H206 P03372 28306507 LALSLTADQMVSALLDAEPPILYSEYDPSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSSDLLLEMLDAHR 5u2b F 2.22 BS01 6WV F 1 L346 A350 E353 L387 M388 M421 I424 H524 L34 A38 E41 L75 M76 M109 I112 H205 P03372 28306507 KKNSLALSLTADQMVSALLDAEPPILYSSMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKLSDLLLEMLDAHR 5u3c A 4.60 BS01 CTP A 1 D147 I148 E149 D147 I148 E149 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c A 4.60 BS02 ADP A 1 L16 G17 K18 I20 R211 K239 D240 V241 L16 G17 K18 I20 R211 K239 D240 V241 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c A 4.60 BS03 CTP B 1 Q114 I116 Q114 I116 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c A 4.60 BS04 CTP C 1 T188 K189 K196 T188 K189 K196 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c B 4.60 BS01 CTP A 1 Q114 I116 Q114 I116 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c B 4.60 BS02 CTP B 1 D147 I148 E149 D147 I148 E149 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c B 4.60 BS03 ADP B 1 L16 G17 K18 G19 I20 R211 K239 D240 V241 L16 G17 K18 G19 I20 R211 K239 D240 V241 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c B 4.60 BS04 CTP D 1 T188 K189 K196 T188 K189 K196 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c C 4.60 BS01 CTP A 1 T188 K189 K196 T188 K189 K196 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c C 4.60 BS02 CTP C 1 S14 D147 I148 E149 S14 D147 I148 E149 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c C 4.60 BS03 ADP C 1 L16 G17 K18 G19 I20 R211 K239 D240 V241 L16 G17 K18 G19 I20 R211 K239 D240 V241 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c D 4.60 BS01 CTP B 1 T188 K189 K196 T188 K189 K196 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c D 4.60 BS02 CTP D 1 S14 D147 I148 E149 S14 D147 I148 E149 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u3c D 4.60 BS03 ADP D 1 L16 G17 K18 G19 I20 R211 K239 D240 V241 L16 G17 K18 G19 I20 R211 K239 D240 V241 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r A 5.70 BS01 CTP A 1 D147 I148 E149 D147 I148 E149 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r A 5.70 BS02 ADP A 1 L16 G17 K18 I20 R211 K239 D240 V241 L16 G17 K18 I20 R211 K239 D240 V241 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r A 5.70 BS03 CTP B 1 Q114 I116 Q114 I116 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r A 5.70 BS04 CTP C 1 T188 K189 K196 T188 K189 K196 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r B 5.70 BS01 CTP A 1 Q114 I116 Q114 I116 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r B 5.70 BS02 CTP B 1 D147 I148 E149 D147 I148 E149 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r B 5.70 BS03 ADP B 1 L16 G17 K18 G19 I20 R211 K239 D240 V241 L16 G17 K18 G19 I20 R211 K239 D240 V241 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r B 5.70 BS04 CTP D 1 T188 K189 K196 T188 K189 K196 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r C 5.70 BS01 CTP A 1 T188 K189 K196 T188 K189 K196 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r C 5.70 BS02 CTP C 1 S14 D147 I148 E149 S14 D147 I148 E149 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r C 5.70 BS03 ADP C 1 L16 G17 K18 G19 I20 R211 K239 D240 V241 L16 G17 K18 G19 I20 R211 K239 D240 V241 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r D 5.70 BS01 CTP B 1 T188 K189 K196 T188 K189 K196 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r D 5.70 BS02 CTP D 1 S14 D147 I148 E149 S14 D147 I148 E149 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u6r D 5.70 BS03 ADP D 1 L16 G17 K18 G19 I20 R211 K239 D240 V241 L16 G17 K18 G19 I20 R211 K239 D240 V241 6.3.4.2 B7MLA1 MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVETMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQA 5u8g A 2.17 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 Y296 H24 S214 K215 G216 E217 T218 K219 Y251 Y276 2.7.7.7,4.2.99.- P06746 28402631 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5u8g A 2.17 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 K234 R254 D256 S94 G95 G97 P98 S99 A100 K219 R234 D236 2.7.7.7,4.2.99.- P06746 28402631 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5u8g A 2.17 BS03 NUC D 1 K35 A38 Y39 P63 G64 G66 K68 I69 K25 A28 Y29 P53 G54 G56 K58 I59 2.7.7.7,4.2.99.- P06746 28402631 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5u8h A 2.16 BS01 NUC T 1 H34 S229 K230 D231 E232 T233 K234 Y271 Y296 H26 S215 K216 D217 E218 T219 K220 Y252 Y277 2.7.7.7,4.2.99.- P06746 28402631 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSKLLHQVVEQLQKVHFITDTLSKDETKFMGVCQLPSEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5u8h A 2.16 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 D190 K234 R254 D256 S96 G97 G99 P100 S101 A102 D182 K220 R235 D237 2.7.7.7,4.2.99.- P06746 28402631 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSKLLHQVVEQLQKVHFITDTLSKDETKFMGVCQLPSEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5u8h A 2.16 BS03 NUC D 1 K35 A38 Y39 G64 G66 K68 I69 K27 A30 Y31 G56 G58 K60 I61 2.7.7.7,4.2.99.- P06746 28402631 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSKLLHQVVEQLQKVHFITDTLSKDETKFMGVCQLPSEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5u8i A 2.45 BS01 NUC T 1 H34 L229 K230 G231 E232 T233 K234 Y271 Y296 H26 L215 K216 G217 E218 T219 K220 Y254 Y279 2.7.7.7,4.2.99.- P06746 28402631 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSKLLHQVVEQLQKVHFITDTLLKGETKFMGVCQLPSKKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5u8i A 2.45 BS02 NUC P 1 S104 G105 I106 G107 P108 S109 A110 D190 K234 M236 D256 S96 G97 I98 G99 P100 S101 A102 D182 K220 M222 D239 2.7.7.7,4.2.99.- P06746 28402631 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSKLLHQVVEQLQKVHFITDTLLKGETKFMGVCQLPSKKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5u8i A 2.45 BS03 NUC D 1 K35 A38 Y39 G64 G66 K68 I69 K27 A30 Y31 G56 G58 K60 I61 2.7.7.7,4.2.99.- P06746 28402631 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSKLLHQVVEQLQKVHFITDTLLKGETKFMGVCQLPSKKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5u9t C 1.92 BS01 ZN C 1 E24 E27 E23 E26 28384393 EWEALEKKLAALESKQALEKKLEALEHG 5u9u A 1.69 BS01 ZN A 1 E24 E27 H28 E23 E26 H27 28384393 EWEALEKKLAALESKQALEKKLEALEHG 5u9u B 1.69 BS01 ZN B 1 E24 H28 E23 H27 28384393 EWEALEKKLAALESKQALEKKLEALEHG 5ufs A 2.12 BS01 III D 1 V41 V44 K48 F53 L58 Q61 M62 L65 Q66 E220 M221 E224 I225 N228 V44 V47 K51 F56 L61 Q64 M65 L68 Q69 E223 M224 E227 I228 N231 28396564 APTLISLLEVIEPEVLYSGYDSTLPDTSTRLMSTLNRLGGRQVVSAVKWAKALPGFRNLHLDDQMTLLQYSWMSLMAFSLGWRSYKQSNGNMLCFAPDLVINEERMQLPYMYDQCQQMLKISSEFVRLQVSYDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEMVGGLLQFCFYTFVNKSLSVEFPEMLAEIISNQLPKFKAGSVKPLLFHQ 5ufs A 2.12 BS02 1TA A 1 M29 L32 N33 L35 G36 Q39 M70 M73 L77 R80 F92 Y107 M108 Q111 M115 F204 C205 T208 V216 F218 M32 L35 N36 L38 G39 Q42 M73 M76 L80 R83 F95 Y110 M111 Q114 M118 F207 C208 T211 V219 F221 28396564 APTLISLLEVIEPEVLYSGYDSTLPDTSTRLMSTLNRLGGRQVVSAVKWAKALPGFRNLHLDDQMTLLQYSWMSLMAFSLGWRSYKQSNGNMLCFAPDLVINEERMQLPYMYDQCQQMLKISSEFVRLQVSYDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEMVGGLLQFCFYTFVNKSLSVEFPEMLAEIISNQLPKFKAGSVKPLLFHQ 5ufs B 2.12 BS01 III C 1 V41 V44 K48 F53 L58 Q61 M62 L65 Q66 E220 M221 E224 I225 N228 V44 V47 K51 F56 L61 Q64 M65 L68 Q69 E223 M224 E227 I228 N231 28396564 APTLISLLEVIEPEVLYSGYDSTLPDTSTRLMSTLNRLGGRQVVSAVKWAKALPGFRNLHLDDQMTLLQYSWMSLMAFSLGWRSYKQSNGNMLCFAPDLVINEERMQLPYMYDQCQQMLKISSEFVRLQVSYDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEMVGGLLQFCFYTFVNKSLSVEFPEMLAEIISNQLPKFKAGSVKPLLFHQ 5ufs B 2.12 BS02 1TA B 1 M29 L32 N33 L35 G36 Q39 M70 M73 L77 R80 F92 Y107 M108 Q111 M115 F204 C205 T208 V216 F218 M32 L35 N36 L38 G39 Q42 M73 M76 L80 R83 F95 Y110 M111 Q114 M118 F207 C208 T211 V219 F221 28396564 APTLISLLEVIEPEVLYSGYDSTLPDTSTRLMSTLNRLGGRQVVSAVKWAKALPGFRNLHLDDQMTLLQYSWMSLMAFSLGWRSYKQSNGNMLCFAPDLVINEERMQLPYMYDQCQQMLKISSEFVRLQVSYDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEMVGGLLQFCFYTFVNKSLSVEFPEMLAEIISNQLPKFKAGSVKPLLFHQ 5uj3 A 1.45 BS01 CE4 A 1 S70 K73 W105 S130 N132 N170 K234 T235 G236 T237 C238 G239 S47 K50 W82 S107 N109 N147 K211 T212 G213 T214 C215 G216 3.5.2.6 Q9F663 28388065 HMLTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAARLALEGLGVN 5uj3 A 1.45 BS02 CE4 A 2 P104 L167 N170 S171 V240 K270 P81 L144 N147 S148 V217 K246 3.5.2.6 Q9F663 28388065 HMLTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAARLALEGLGVN 5uj4 A 1.40 BS01 SFR A 1 S70 K73 W105 S130 N132 T216 K234 T235 G236 T237 S47 K50 W82 S107 N109 T193 K211 T212 G213 T214 3.5.2.6 Q9F663 28388065 HMLTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAARLALEGLGV 5uoy A 1.82 BS01 ZN A 1 H227 H263 D264 D370 H78 H114 D115 D221 3.1.4.17 Q01064 28406621 YSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVPDVVSFRSTWVKRIQENKQKWKERAA 5uoy A 1.82 BS02 8HM A 1 Y222 M336 H373 L388 M389 F392 P408 L409 T415 S420 Q421 F424 Y73 M187 H224 L239 M240 F243 P259 L260 T266 S271 Q272 F275 3.1.4.17 Q01064 28406621 YSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVPDVVSFRSTWVKRIQENKQKWKERAA 5uoy A 1.82 BS03 8HM A 2 Y150 R181 T182 F185 T201 M205 Y1 R32 T33 F36 T52 M56 3.1.4.17 Q01064 28406621 YSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVPDVVSFRSTWVKRIQENKQKWKERAA 5up0 A 2.04 BS01 ZN A 1 H227 H263 D264 D370 H78 H114 D115 D221 3.1.4.17 Q01064 28406621 YSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVPDVVSFRSTWVKRIQENKQKWKERAA 5up0 A 2.04 BS02 8HP A 1 H373 L388 M389 F392 L409 S420 Q421 F424 H224 L239 M240 F243 L260 S271 Q272 F275 3.1.4.17 Q01064 28406621 YSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVPDVVSFRSTWVKRIQENKQKWKERAA 5uv4 A 2.30 BS01 ANP A 1 I767 G768 S770 H772 S775 K789 Y838 A839 A841 S843 N888 K890 S892 N893 L895 D907 I24 G25 S27 H29 S32 K46 Y95 A96 A98 S100 N145 K147 S149 N150 L152 D164 K7VIQ3 DLHLFDNSVVFTAEELSCAPAEIIGRSCHGTSYKATLDNGYMLTVKWLKEGFAKSKKEFSREIKKLGSVRHPNLVPLRGYYWGPKEHERIMISDYADATSLSTYLSEFDERNLPPLSAGQRLNIAIDIARCLDYLHNERVIPHGNIKSSNVLIQNSTPSALVTDYSLHRLMTPIGMAEQVLNAGALGYSPPEFSSTSKPCPSLKSDVYAFGVILLELLTGKIAGEIICMVDLTDWVRMLDLEERVSECYDRHIAPQALDGMLRIALRCIRSASERPEVRTVFEDLLSLSS 5uv4 A 2.30 BS02 MG A 1 N893 T906 D907 N150 T163 D164 K7VIQ3 DLHLFDNSVVFTAEELSCAPAEIIGRSCHGTSYKATLDNGYMLTVKWLKEGFAKSKKEFSREIKKLGSVRHPNLVPLRGYYWGPKEHERIMISDYADATSLSTYLSEFDERNLPPLSAGQRLNIAIDIARCLDYLHNERVIPHGNIKSSNVLIQNSTPSALVTDYSLHRLMTPIGMAEQVLNAGALGYSPPEFSSTSKPCPSLKSDVYAFGVILLELLTGKIAGEIICMVDLTDWVRMLDLEERVSECYDRHIAPQALDGMLRIALRCIRSASERPEVRTVFEDLLSLSS 5uwf C 1.87 BS01 8Q7 C 1 Y524 H525 L675 S677 V678 I692 Y693 F696 I711 M713 M714 Q726 F729 Y79 H80 L230 S232 V233 I247 Y248 F251 I266 M268 M269 Q281 F284 3.1.4.17,3.1.4.35 Q9Y233 28406621 SMASICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRG 5uwf C 1.87 BS02 ZN C 1 H529 H563 D564 D674 H84 H118 D119 D229 3.1.4.17,3.1.4.35 Q9Y233 28406621 SMASICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRG 5uwf D 1.87 BS01 8Q7 D 1 Y524 H525 L675 V678 I692 Y693 E695 F696 M713 Q726 F729 V733 Y79 H80 L230 V233 I247 Y248 E250 F251 M268 Q281 F284 V288 3.1.4.17,3.1.4.35 Q9Y233 28406621 SMASICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5uwf D 1.87 BS02 ZN D 1 H529 H563 D564 D674 H84 H118 D119 D229 3.1.4.17,3.1.4.35 Q9Y233 28406621 SMASICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5ux5 A 2.70 BS01 FAD A 1 D230 M231 V261 Q263 Y265 R294 V296 K297 G298 A299 L301 Y318 T320 K321 V324 A348 S349 H350 N351 E374 M375 L376 N420 D138 M139 V169 Q171 Y173 R202 V204 K205 G206 A207 L209 Y226 T228 K229 V232 A256 S257 H258 N259 E282 M283 L284 N328 1.5.5.22,1.2.1.88 LMSYINRDLENLQERIIARANEWLAARLRQMVSHLVLDAEGKALNKLLDESKAKGYRLNVNLLGEAVLGDGEANNRLTRTMELLKNPRVDYVSIKATSVVAQLNPWDIDGNTELLKERLRPLYRLALQRSPHPFINLDMEEYKDLHVTIRLFEELLMEEEFLGLEAGIVLQAYLPDSFQALQQLADFAKRRAAAGGAKIKIRLVKGANLSMEKVDAELHGWYPAPYATKEEVDANFLRMMDYILRPEHENVRVGIASHNLFSVASAYELSVERGVETQLDVEMLQGMAPAQAEAVRQAVGTVILYTPVVHAEDFDVAVSYLVRRLEENLTEQEARFRESVAQRWKVAEDSRRLSTPETFNASDSDPALLSTLEWARTLEDPQPKWRLITDVEEVDKTVAGLLKSPRLDIAERTALLQRAADELENIRQDLLGVMTHEAGKTIAEADPEVSEAIDFARYYARCANALNTPGHSKFTPHNLVVVASPWNFPVAIPLGGVFASLAAGAKAILKPAPEVRRCAEVALTALRKAGIGEDLVQLMHTDEADAGRRLMSHPDVDAIILTGASETASLFRGWKPEMNIHAETSGKNAIIVTPSADPDLAVADVYKSAFGHAGQKCSAASLVILVGDVGRFTDQLIDATRTLRVGYGHELSTTMNGLISPPGEKLHRGLTTLETGESWLVKPEKLNDEGTLWSPGIRDNVRPGSWFHTHECFGPVLGIMHAESLEQAIEWQNSTGFGLTGGIHSLDEDEVELWKEKVEVGNAYINRGITGAIVQRQPFGGWKNSSVGVGAKAGGPNYVAQLGTWEDIESDVPSVSLPPAYRELANTEFLKRAAALDEIAWRTEFGVEQDFTGLRCESNVFRYRPLETLYVVGDDEEQFNRLKLAALRTGTELRKLETHEWFPPHSRIRAIGDAPVPTTIYEWAALNGSVVIDGPVLADGRRELLHFLKEQAVSTTNHRFGYI 5ux5 A 2.70 BS02 NAD A 1 S590 W592 K616 P617 A618 P619 D648 E649 G653 G669 A670 T673 F677 W680 E817 F819 S484 W486 K510 P511 A512 P513 D542 E543 G547 G563 A564 T567 F571 W574 E711 F713 1.5.5.22,1.2.1.88 LMSYINRDLENLQERIIARANEWLAARLRQMVSHLVLDAEGKALNKLLDESKAKGYRLNVNLLGEAVLGDGEANNRLTRTMELLKNPRVDYVSIKATSVVAQLNPWDIDGNTELLKERLRPLYRLALQRSPHPFINLDMEEYKDLHVTIRLFEELLMEEEFLGLEAGIVLQAYLPDSFQALQQLADFAKRRAAAGGAKIKIRLVKGANLSMEKVDAELHGWYPAPYATKEEVDANFLRMMDYILRPEHENVRVGIASHNLFSVASAYELSVERGVETQLDVEMLQGMAPAQAEAVRQAVGTVILYTPVVHAEDFDVAVSYLVRRLEENLTEQEARFRESVAQRWKVAEDSRRLSTPETFNASDSDPALLSTLEWARTLEDPQPKWRLITDVEEVDKTVAGLLKSPRLDIAERTALLQRAADELENIRQDLLGVMTHEAGKTIAEADPEVSEAIDFARYYARCANALNTPGHSKFTPHNLVVVASPWNFPVAIPLGGVFASLAAGAKAILKPAPEVRRCAEVALTALRKAGIGEDLVQLMHTDEADAGRRLMSHPDVDAIILTGASETASLFRGWKPEMNIHAETSGKNAIIVTPSADPDLAVADVYKSAFGHAGQKCSAASLVILVGDVGRFTDQLIDATRTLRVGYGHELSTTMNGLISPPGEKLHRGLTTLETGESWLVKPEKLNDEGTLWSPGIRDNVRPGSWFHTHECFGPVLGIMHAESLEQAIEWQNSTGFGLTGGIHSLDEDEVELWKEKVEVGNAYINRGITGAIVQRQPFGGWKNSSVGVGAKAGGPNYVAQLGTWEDIESDVPSVSLPPAYRELANTEFLKRAAALDEIAWRTEFGVEQDFTGLRCESNVFRYRPLETLYVVGDDEEQFNRLKLAALRTGTELRKLETHEWFPPHSRIRAIGDAPVPTTIYEWAALNGSVVIDGPVLADGRRELLHFLKEQAVSTTNHRFGYI 5ux5 B 2.70 BS01 FAD B 1 M231 V261 Q263 Y265 R294 V296 K297 G298 A299 L301 Y318 T320 K321 V324 A348 S349 H350 N351 E374 M375 L376 Y397 N420 M138 V168 Q170 Y172 R201 V203 K204 G205 A206 L208 Y225 T227 K228 V231 A255 S256 H257 N258 E281 M282 L283 Y304 N327 1.5.5.22,1.2.1.88 LMSYINRDLENLQERIIARANEWLARLRQMVSHLVLDAEGKALNKLLDESKAKGYRLNVNLLGEAVLGDGEANNRLTRTMELLKNPRVDYVSIKATSVVAQLNPWDIDGNTELLKERLRPLYRLALQRSPHPFINLDMEEYKDLHVTIRLFEELLMEEEFLGLEAGIVLQAYLPDSFQALQQLADFAKRRAAAGGAKIKIRLVKGANLSMEKVDAELHGWYPAPYATKEEVDANFLRMMDYILRPEHENVRVGIASHNLFSVASAYELSVERGVETQLDVEMLQGMAPAQAEAVRQAVGTVILYTPVVHAEDFDVAVSYLVRRLEENLTEQEARFRESVAQRWKVAEDSRRLSTPETFNASDSDPALLSTLEWARTLEDPQPKWRLITDVEEVDKTVAGLLKSPRLDIAERTALLQRAADELENIRQDLLGVMTHEAGKTIAEADPEVSEAIDFARYYARCANALNTPGHSKFTPHNLVVVASPWNFPVAIPLGGVFASLAAGAKAILKPAPEVRRCAEVALTALRKAGIGEDLVQLMHTDEADAGRRLMSHPDVDAIILTGASETASLFRGWKPEMNIHAETSGKNAIIVTPSADPDLAVADVYKSAFGHAGQKCSAASLVILVGDVGRFTDQLIDATRTLRVGYGHELSTTMNGLISPPGEKLHRGLTTLETGESWLVKPEKLNDEGTLWSPGIRDNVRPGSWFHTHECFGPVLGIMHAESLEQAIEWQNSTGFGLTGGIHSLDEDEVELWKEKVEVGNAYINRGITGAIVQRQPFGGWKNSSVGVGAKAGGPNYVAQLGTWEDIESDVPSVSLPPAYRELANTEFLKRAAALDEIAWRTEFGVEQDFTGLRCESNVFRYRPLETLYVVGDDEEQFNRLKLAALRTGTELRKLETHEWFPPHSRIRAIGDAPVPTTIYEWAALNGSVVIDGPVLADGRRELLHFLKEQAVSTTNHRFGYI 5ux5 B 2.70 BS02 NAD B 1 S590 W592 K616 A618 P619 D648 E649 G653 M657 G669 A670 T673 F677 W680 F819 S483 W485 K509 A511 P512 D541 E542 G546 M550 G562 A563 T566 F570 W573 F712 1.5.5.22,1.2.1.88 LMSYINRDLENLQERIIARANEWLARLRQMVSHLVLDAEGKALNKLLDESKAKGYRLNVNLLGEAVLGDGEANNRLTRTMELLKNPRVDYVSIKATSVVAQLNPWDIDGNTELLKERLRPLYRLALQRSPHPFINLDMEEYKDLHVTIRLFEELLMEEEFLGLEAGIVLQAYLPDSFQALQQLADFAKRRAAAGGAKIKIRLVKGANLSMEKVDAELHGWYPAPYATKEEVDANFLRMMDYILRPEHENVRVGIASHNLFSVASAYELSVERGVETQLDVEMLQGMAPAQAEAVRQAVGTVILYTPVVHAEDFDVAVSYLVRRLEENLTEQEARFRESVAQRWKVAEDSRRLSTPETFNASDSDPALLSTLEWARTLEDPQPKWRLITDVEEVDKTVAGLLKSPRLDIAERTALLQRAADELENIRQDLLGVMTHEAGKTIAEADPEVSEAIDFARYYARCANALNTPGHSKFTPHNLVVVASPWNFPVAIPLGGVFASLAAGAKAILKPAPEVRRCAEVALTALRKAGIGEDLVQLMHTDEADAGRRLMSHPDVDAIILTGASETASLFRGWKPEMNIHAETSGKNAIIVTPSADPDLAVADVYKSAFGHAGQKCSAASLVILVGDVGRFTDQLIDATRTLRVGYGHELSTTMNGLISPPGEKLHRGLTTLETGESWLVKPEKLNDEGTLWSPGIRDNVRPGSWFHTHECFGPVLGIMHAESLEQAIEWQNSTGFGLTGGIHSLDEDEVELWKEKVEVGNAYINRGITGAIVQRQPFGGWKNSSVGVGAKAGGPNYVAQLGTWEDIESDVPSVSLPPAYRELANTEFLKRAAALDEIAWRTEFGVEQDFTGLRCESNVFRYRPLETLYVVGDDEEQFNRLKLAALRTGTELRKLETHEWFPPHSRIRAIGDAPVPTTIYEWAALNGSVVIDGPVLADGRRELLHFLKEQAVSTTNHRFGYI 5ux5 C 2.70 BS01 FAD C 1 M231 V261 Q263 R294 V296 K297 G298 A299 L301 Y318 A319 T320 K321 V324 A348 S349 H350 N351 E374 M375 L376 M138 V168 Q170 R201 V203 K204 G205 A206 L208 Y225 A226 T227 K228 V231 A255 S256 H257 N258 E281 M282 L283 1.5.5.22,1.2.1.88 LMSYINRDLENLQERIIARANEWLARLRQMVSHLVLDAEGKALNKLLDESKAKGYRLNVNLLGEAVLGDGEANNRLTRTMELLKNPRVDYVSIKATSVVAQLNPWDIDGNTELLKERLRPLYRLALQRSPHPFINLDMEEYKDLHVTIRLFEELLMEEEFLGLEAGIVLQAYLPDSFQALQQLADFAKRRAAAGGAKIKIRLVKGANLSMEKVDAELHGWYPAPYATKEEVDANFLRMMDYILRPEHENVRVGIASHNLFSVASAYELSVERGVETQLDVEMLQGMAPAQAEAVRQAVGTVILYTPVVHAEDFDVAVSYLVRRLEENLTEQEARFRESVAQRWKVAEDSRRLSTPETFNASDSDPALLSTLEWARTLEDPQPKWRLITDVEEVDKTVAGLLKSPRLDIAERTALLQRAADELENIRQDLLGVMTHEAGKTIAEADPEVSEAIDFARYYARCANALNTPGHSKFTPHNLVVVASPWNFPVAIPLGGVFASLAAGAKAILKPAPEVRRCAEVALTALRKAGIGEDLVQLMHTDEADAGRRLMSHPDVDAIILTGASETASLFRGWKPEMNIHAETSGKNAIIVTPSADPDLAVADVYKSAFGHAGQKCSAASLVILVGDVGRFTDQLIDATRTLRVGYGHELSTTMNGLISPPGEKLHRGLTTLETGESWLVKPEKLNDEGTLWSPGIRDNVRPGSWFHTHECFGPVLGIMHAESLEQAIEWQNSTGFGLTGGIHSLDEDEVELWKEKVEVGNAYINRGITGAIVQRQPFGGWKNSSVGVGAKAGGPNYVAQLGTWEDIESDVPSVSLPPAYRELANTEFLKRAAALDEIAWRTEFGVEQDFTGLRCESNVFRYRPLETLYVVGDDEEQFNRLKLAALRTGTELRKLETHEWFPPHSRIRAIGDAPVPTTIYEWAALNGSVVIDGPVLADGRRELLHFLKEQAVSTTNHRFGYI 5ux5 C 2.70 BS02 NAD C 1 S590 W592 K616 A618 P619 D648 E649 G653 L667 T668 G669 A670 T673 L676 F677 W680 E817 F819 S483 W485 K509 A511 P512 D541 E542 G546 L560 T561 G562 A563 T566 L569 F570 W573 E710 F712 1.5.5.22,1.2.1.88 LMSYINRDLENLQERIIARANEWLARLRQMVSHLVLDAEGKALNKLLDESKAKGYRLNVNLLGEAVLGDGEANNRLTRTMELLKNPRVDYVSIKATSVVAQLNPWDIDGNTELLKERLRPLYRLALQRSPHPFINLDMEEYKDLHVTIRLFEELLMEEEFLGLEAGIVLQAYLPDSFQALQQLADFAKRRAAAGGAKIKIRLVKGANLSMEKVDAELHGWYPAPYATKEEVDANFLRMMDYILRPEHENVRVGIASHNLFSVASAYELSVERGVETQLDVEMLQGMAPAQAEAVRQAVGTVILYTPVVHAEDFDVAVSYLVRRLEENLTEQEARFRESVAQRWKVAEDSRRLSTPETFNASDSDPALLSTLEWARTLEDPQPKWRLITDVEEVDKTVAGLLKSPRLDIAERTALLQRAADELENIRQDLLGVMTHEAGKTIAEADPEVSEAIDFARYYARCANALNTPGHSKFTPHNLVVVASPWNFPVAIPLGGVFASLAAGAKAILKPAPEVRRCAEVALTALRKAGIGEDLVQLMHTDEADAGRRLMSHPDVDAIILTGASETASLFRGWKPEMNIHAETSGKNAIIVTPSADPDLAVADVYKSAFGHAGQKCSAASLVILVGDVGRFTDQLIDATRTLRVGYGHELSTTMNGLISPPGEKLHRGLTTLETGESWLVKPEKLNDEGTLWSPGIRDNVRPGSWFHTHECFGPVLGIMHAESLEQAIEWQNSTGFGLTGGIHSLDEDEVELWKEKVEVGNAYINRGITGAIVQRQPFGGWKNSSVGVGAKAGGPNYVAQLGTWEDIESDVPSVSLPPAYRELANTEFLKRAAALDEIAWRTEFGVEQDFTGLRCESNVFRYRPLETLYVVGDDEEQFNRLKLAALRTGTELRKLETHEWFPPHSRIRAIGDAPVPTTIYEWAALNGSVVIDGPVLADGRRELLHFLKEQAVSTTNHRFGYI 5ux5 D 2.70 BS01 FAD D 1 M231 V261 Q263 R294 V296 K297 G298 A299 L301 T320 K321 V324 A348 S349 H350 N351 E374 M375 L376 N420 M138 V168 Q170 R201 V203 K204 G205 A206 L208 T227 K228 V231 A255 S256 H257 N258 E281 M282 L283 N327 1.5.5.22,1.2.1.88 LMSYINRDLENLQERIIARANEWLARLRQMVSHLVLDAEGKALNKLLDESKAKGYRLNVNLLGEAVLGDGEANNRLTRTMELLKNPRVDYVSIKATSVVAQLNPWDIDGNTELLKERLRPLYRLALQRSPHPFINLDMEEYKDLHVTIRLFEELLMEEEFLGLEAGIVLQAYLPDSFQALQQLADFAKRRAAAGGAKIKIRLVKGANLSMEKVDAELHGWYPAPYATKEEVDANFLRMMDYILRPEHENVRVGIASHNLFSVASAYELSVERGVETQLDVEMLQGMAPAQAEAVRQAVGTVILYTPVVHAEDFDVAVSYLVRRLEENLTEQEARFRESVAQRWKVAEDSRRLSTPETFNASDSDPALLSTLEWARTLEDPQPKWRLITDVEEVDKTVAGLLKSPRLDIAERTALLQRAADELENIRQDLLGVMTHEAGKTIAEADPEVSEAIDFARYYARCANALNTPGHSKFTPHNLVVVASPWNFPVAIPLGGVFASLAAGAKAILKPAPEVRRCAEVALTALRKAGIGEDLVQLMHTDEADAGRRLMSHPDVDAIILTGASETASLFRGWKPEMNIHAETSGKNAIIVTPSADPDLAVADVYKSAFGHAGQKCSAASLVILVGDVGRFTDQLIDATRTLRVGYGHELSTTMNGLISPPGEKLHRGLTTLETGESWLVKPEKLNDEGTLWSPGIRDNVRPGSWFHTHECFGPVLGIMHAESLEQAIEWQNSTGFGLTGGIHSLDEDEVELWKEKVEVGNAYINRGITGAIVQRQPFGGWKNSSVGVGAKAGGPNYVAQLGTWEDIESDVPSVSLPPAYRELANTEFLKRAAALDEIAWRTEFGVEQDFTGLRCESNVFRYRPLETLYVVGDDEEQFNRLKLAALRTGTELRKLETHEWFPPHSRIRAIGDAPVPTTIYEWAALNGSVVIDGPVLADGRRELLHFLKEQAVSTTNHRFGYI 5ux5 D 2.70 BS02 NAD D 1 S590 W592 K616 A618 P619 D648 E649 G653 M657 T668 G669 A670 T673 F677 W680 S483 W485 K509 A511 P512 D541 E542 G546 M550 T561 G562 A563 T566 F570 W573 1.5.5.22,1.2.1.88 LMSYINRDLENLQERIIARANEWLARLRQMVSHLVLDAEGKALNKLLDESKAKGYRLNVNLLGEAVLGDGEANNRLTRTMELLKNPRVDYVSIKATSVVAQLNPWDIDGNTELLKERLRPLYRLALQRSPHPFINLDMEEYKDLHVTIRLFEELLMEEEFLGLEAGIVLQAYLPDSFQALQQLADFAKRRAAAGGAKIKIRLVKGANLSMEKVDAELHGWYPAPYATKEEVDANFLRMMDYILRPEHENVRVGIASHNLFSVASAYELSVERGVETQLDVEMLQGMAPAQAEAVRQAVGTVILYTPVVHAEDFDVAVSYLVRRLEENLTEQEARFRESVAQRWKVAEDSRRLSTPETFNASDSDPALLSTLEWARTLEDPQPKWRLITDVEEVDKTVAGLLKSPRLDIAERTALLQRAADELENIRQDLLGVMTHEAGKTIAEADPEVSEAIDFARYYARCANALNTPGHSKFTPHNLVVVASPWNFPVAIPLGGVFASLAAGAKAILKPAPEVRRCAEVALTALRKAGIGEDLVQLMHTDEADAGRRLMSHPDVDAIILTGASETASLFRGWKPEMNIHAETSGKNAIIVTPSADPDLAVADVYKSAFGHAGQKCSAASLVILVGDVGRFTDQLIDATRTLRVGYGHELSTTMNGLISPPGEKLHRGLTTLETGESWLVKPEKLNDEGTLWSPGIRDNVRPGSWFHTHECFGPVLGIMHAESLEQAIEWQNSTGFGLTGGIHSLDEDEVELWKEKVEVGNAYINRGITGAIVQRQPFGGWKNSSVGVGAKAGGPNYVAQLGTWEDIESDVPSVSLPPAYRELANTEFLKRAAALDEIAWRTEFGVEQDFTGLRCESNVFRYRPLETLYVVGDDEEQFNRLKLAALRTGTELRKLETHEWFPPHSRIRAIGDAPVPTTIYEWAALNGSVVIDGPVLADGRRELLHFLKEQAVSTTNHRFGYI 5uy9 A 1.85 BS01 III B 1 K63 R68 R69 S114 S115 D121 L122 M130 S154 K46 R51 R52 S97 S98 D104 L105 M113 S137 5.2.1.8 Q13526 KLPPGWEKAMSRSSGRVYYFNHITNASQWERPSEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 5uyj A 1.60 BS01 8R7 A 1 I171 K173 G174 V179 A192 K194 F267 E268 L269 V270 N271 G273 S316 N317 L319 A329 D330 I13 K15 G16 V21 A34 K36 F99 E100 L101 V102 N103 G105 S148 N149 L151 A161 D162 2.7.11.17 Q96RR4 SMQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRH 5uz9 A 3.40 BS01 NUC M 1 I73 S173 L174 K176 Q177 L178 Y179 Y187 L193 I63 S163 L164 K166 Q167 L168 Y169 Y177 L183 Q02ML9 28340349 QELRQFIESFIQERLQGKLDKLQPDEDDKRQTLLATHRREAWLADAARRVGQLQLVTHTLKPIHPDARGSNLHSLPQAPGQPGLAGSHELGDRLVSDVVGNAAALDVFKFLSLQYQGKNLLNWLTEDSAEALQALSDNAEQAREWRQAFIGITTVKGAPASHSLAKQLYFPLPGSGYHLLAPLFPTSLVHHVHALLREARFGDAAKAAREARSRQESWPHGFSEYPNLAIQKFGGTKPQNISQLNNERRGENWLLPSLPPNWQRQNVNAPMRHSSVFEHDFGRTPEVSRLTRTLQRFLAKTVHNNLAIRQRRAQLVAQICDEALQYAARLRELEPGWSATPGCQLHDAEQLWLDPLRAQTDETFLQRRLRGDWPAEVGNRFANWLNRAVSSDSQILGSPEAAQWSQELSKELTMFKEILEDERD 5uz9 B 3.40 BS01 NUC M 1 N21 P26 A36 F40 R46 T84 R85 N86 M137 R138 L139 G141 R271 N19 P24 A34 F38 R44 T82 R83 N84 M135 R136 L137 G139 R254 Q02MM0 28340349 VTDPEALLLLPRLSIQNANAISSPLTWGFPSPGAFTGFVHALQRRVGISLDIELDGVGIVCHRFEAQISQPAGKRTKVFNLTRNPLNRDGSTAAIVEEGRAHLEVSLLLGVHGDGLDDHPAQEIARQVQEQAGAMRLAGGSILPWCNERFPAPNAELLMLGGSDEQRRKNQRRLTRRLLPGFALVSREALLQQHLETLRTTLPEATTLDALLDLCRINFEPWQVRDKPGWLVPIPAGYNALSPLYLPGEVRNARDRETPLRFVENLFGLGEWLSPHRVAALSDLLWYHHAEPDKGLYRWSTPRFV 5uz9 C 3.40 BS01 NUC M 1 F33 E34 R35 Q96 W168 Q248 E249 L250 K263 Q277 K278 N281 R284 T308 G353 V354 F9 E10 R11 Q44 W116 Q196 E197 L198 K199 Q213 K214 N217 R220 T244 G289 V290 Q02MM1 28340349 LSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSQTVDVANLPSDADTLKVRFTLRVLGGAGTPSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVGAEAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLSGSGHVLLEVVAFARIGDGQEVFPSQELKTLYSVRDAAAIHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFYTLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGE 5uz9 D 3.40 BS01 NUC M 1 F33 E34 R35 V68 R69 G70 T71 L95 R169 Q248 E249 L250 H275 Q277 K278 N281 R284 T308 S309 R351 G353 V354 F9 E10 R11 V44 R45 G46 T47 L71 R145 Q224 E225 L226 H251 Q253 K254 N257 R260 T284 S285 R327 G329 V330 Q02MM1 28340349 LSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISNRLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAGTPSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVGAEAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLSGSGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAAIHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFYTLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGE 5uz9 E 3.40 BS01 NUC M 1 E34 R35 V68 R69 G70 L95 W168 R169 Q248 L250 H275 Q277 K278 N281 R284 T308 S309 R351 G353 V354 E11 R12 V45 R46 G47 L72 W145 R146 Q225 L227 H252 Q254 K255 N258 R261 T285 S286 R328 G330 V331 Q02MM1 28340349 ILSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISNRLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAGTPSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVGAEAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLSGSGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAAIHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFYTLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGE 5uz9 F 3.40 BS01 NUC M 1 E34 R35 V68 R69 G70 L95 W168 R169 S247 Q248 E249 L250 H275 Q277 K278 N281 R284 T308 R351 G353 V354 E11 R12 V45 R46 G47 L72 W145 R146 S224 Q225 E226 L227 H252 Q254 K255 N258 R261 T285 R328 G330 V331 Q02MM1 28340349 ILSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISNRLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAGTPSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVGAEAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLSGSGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAAIHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFYTLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGEA 5uz9 G 3.40 BS01 NUC M 1 F33 E34 R35 V68 R69 L95 Q96 R169 Q248 L250 H275 Q277 K278 N281 R284 S309 R351 G353 V354 F9 E10 R11 V44 R45 L71 Q72 R145 Q224 L226 H251 Q253 K254 N257 R260 S285 R327 G329 V330 Q02MM1 28340349 LSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISNRLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAGTPSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVGAEAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLSGSGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAAIHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFYTLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGE 5uz9 H 3.40 BS01 NUC M 1 A32 F33 R35 V68 R69 G70 L95 A127 W168 R169 Q248 E249 H275 Q277 K278 N281 R284 T308 G353 V354 A8 F9 R11 V44 R45 G46 L71 A103 W144 R145 Q224 E225 H251 Q253 K254 N257 R260 T284 G329 V330 Q02MM1 28340349 LSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISNRLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAGTPSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVGAEAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLSGSGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAAIHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFYTLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGE 5uz9 J 3.40 BS01 NUC M 1 Y14 L62 Y13 L61 L7P7M1 28340349 KFIKYLSTAHLNYMNIAVYENGSKIKARVENVVNGKSVGARDFDSTEQLESWFYGLPGSGLGRIENAMNEISRREN 5uz9 L 3.40 BS01 NUC M 1 P13 V103 Q104 R111 R115 L146 S148 Q149 S150 F155 R156 P15 V105 Q106 R113 R117 L148 S150 Q151 S152 F157 R158 3.1.-.- Q02MM2 28340349 FTMDHYLDIRLRPDPEFPPAQLMCVLFGKLHQALVAQGGDRIGVSFPDLDESRSRLGERLRIHASADDLRALLARPWLEGLRDHLQFGEPAVVPHPTPYRQVSRVQAKSNPERLRRRLMRRHDLSEEEARKRIPDTVARALDLPFVTLRSQSTGQHFRLFIRHGPLQVTAEEGGFTCYGLSKGGFVPWF 5v3u A 2.50 BS01 HEM A 1 I38 F39 P40 T46 K49 Q50 F53 L54 Y64 L73 H77 F80 I82 A87 L90 A119 M122 I37 F38 P39 T45 K48 Q49 F52 L53 Y63 L72 H76 F79 I81 A86 L89 A118 M121 Q81TQ7 SKQPMTPFEAIGGEQCIEILVDTFYSYVSKHPDLSPIFPDDLTETARKQKQFLTQYLGGPNLYTEEHGHPMLRARHLPFEITPKRAEALLSCMEQAMDDTGVHGHIREFVFERLALTAQHMVNTPNETGEI 5v3u B 2.50 BS01 HEM A 1 R114 L117 R110 L113 Q81TQ7 PMTPFEAIGGEQCIEILVDTFYSYVSKHPDLSPIFPDDLTETARKQKQFLTQYLGGPNLYTEEHGHPMLRARHLPFEITPKRAEALLSCMEQAMDDTGVHGHIREFVFERLALTAQHMVNTPN 5v3u B 2.50 BS02 HEM B 1 I38 F39 T46 K49 Q50 F53 Y64 L73 H77 F80 I82 A87 L90 T118 A119 I34 F35 T42 K45 Q46 F49 Y60 L69 H73 F76 I78 A83 L86 T114 A115 Q81TQ7 PMTPFEAIGGEQCIEILVDTFYSYVSKHPDLSPIFPDDLTETARKQKQFLTQYLGGPNLYTEEHGHPMLRARHLPFEITPKRAEALLSCMEQAMDDTGVHGHIREFVFERLALTAQHMVNTPN 5v4o A 1.95 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5v4o A 1.95 BS02 OXY A 1 R108 W111 H112 R73 W76 H77 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5v4o B 1.95 BS01 HEM B 1 G104 L105 I107 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 W420 G69 L70 I72 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 T353 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5v4o B 1.95 BS02 OXY B 1 R108 W111 H112 R73 W76 H77 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5v53 A 1.70 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 F261 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 L326 W330 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 F226 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 L291 W295 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5v53 A 1.70 BS02 OXY A 1 R108 H112 A141 R73 H77 A106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5v53 B 1.70 BS01 HEM B 1 G104 L105 I107 R108 W111 V239 P241 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 T388 F416 W420 G69 L70 I72 R73 W76 V204 P206 L239 I240 G243 H244 G247 K248 T249 H250 T288 S289 W295 T353 F381 W385 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5v53 B 1.70 BS02 OXY B 1 R108 H112 A141 R73 H77 A106 1.11.1.21 Q3JNW6 28409923 GTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPANANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVEMGLIYVDPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 5v78 K 5.90 BS01 5QF K 1 F136 V139 Q176 L177 F178 G179 I277 A279 S287 G288 P326 Y327 M573 F610 V612 F615 R620 F628 L668 F136 V139 Q176 L177 F178 G179 I277 A279 S287 G288 P326 Y327 M573 F610 V612 F615 R620 F628 L668 P31224 28355133 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKN 5v78 L 5.90 BS01 5QF L 1 F136 V139 F178 G179 I277 A279 S287 G288 P326 Y327 M573 F610 V612 F615 R620 F628 L668 F136 V139 F178 G179 I277 A279 S287 G288 P326 Y327 M573 F610 V612 F615 R620 F628 L668 P31224 28355133 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKN 5v78 J 5.90 BS01 5QF J 1 F136 V139 Q151 F178 G179 I277 A279 A286 S287 G288 P326 Y327 V571 M573 F610 V612 F615 F617 R620 F628 L668 F136 V139 Q151 F178 G179 I277 A279 A286 S287 G288 P326 Y327 V571 M573 F610 V612 F615 F617 R620 F628 L668 P31224 28355133 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRF 5va8 A 1.60 BS01 NAP A 1 A14 S16 K17 G18 L19 A38 R39 T40 C64 D65 I66 T67 N88 A89 G90 G91 T139 R157 P183 G184 I185 F186 T188 R190 I191 A16 S18 K19 G20 L21 A40 R41 T42 C66 D67 I68 T69 N90 A91 G92 G93 T141 R159 P185 G186 I187 F188 T190 R192 I193 B2JE32 HHMDLGIAGKSALVCAASKGLGRGCAEALAAEGVNVTIVARTPETLDATAAAIRANAGVDVQAVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHDDWIRALEANMLTPIELIRATIDGMISRGFGRVVNITSSSVKAPIDVLGLSNGARSGLTGFIAGVARKVAPNGVTINNLLPGIFDTDRIAVTFDAAAKAQNISVDEARKQRMATIPARRFGTPDEFGRACAFLCSVHAGYITGQNWLIDGGAYPGTY 5va8 A 1.60 BS02 TCE A 1 S140 S141 I147 L150 S153 R157 G184 I185 T194 R213 S142 S143 I149 L152 S155 R159 G186 I187 T196 R215 B2JE32 HHMDLGIAGKSALVCAASKGLGRGCAEALAAEGVNVTIVARTPETLDATAAAIRANAGVDVQAVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHDDWIRALEANMLTPIELIRATIDGMISRGFGRVVNITSSSVKAPIDVLGLSNGARSGLTGFIAGVARKVAPNGVTINNLLPGIFDTDRIAVTFDAAAKAQNISVDEARKQRMATIPARRFGTPDEFGRACAFLCSVHAGYITGQNWLIDGGAYPGTY 5va8 B 1.60 BS01 NAP B 1 A14 S16 K17 G18 L19 A38 R39 T40 C64 D65 I66 T67 N88 A89 G90 G91 T139 R157 P183 G184 I185 F186 T188 I191 A16 S18 K19 G20 L21 A40 R41 T42 C66 D67 I68 T69 N90 A91 G92 G93 T141 R159 P185 G186 I187 F188 T190 I193 B2JE32 HHMDLGIAGKSALVCAASKGLGRGCAEALAAEGVNVTIVARTPETLDATAAAIRANAGVDVQAVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHDDWIRALEANMLTPIELIRATIDGMISRGFGRVVNITSSSVKAPIDVLGLSNGARSGLTGFIAGVARKVAPNGVTINNLLPGIFDTDRIAVTFDAAAKAQNISVDEARKQRMATIPARRFGTPDEFGRACAFLCSVHAGYITGQNWLIDGGAYPGTY 5va8 B 1.60 BS02 TCE B 1 S140 S141 I147 L150 S153 R157 G184 I191 T194 R213 S142 S143 I149 L152 S155 R159 G186 I193 T196 R215 B2JE32 HHMDLGIAGKSALVCAASKGLGRGCAEALAAEGVNVTIVARTPETLDATAAAIRANAGVDVQAVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHDDWIRALEANMLTPIELIRATIDGMISRGFGRVVNITSSSVKAPIDVLGLSNGARSGLTGFIAGVARKVAPNGVTINNLLPGIFDTDRIAVTFDAAAKAQNISVDEARKQRMATIPARRFGTPDEFGRACAFLCSVHAGYITGQNWLIDGGAYPGTY 5va8 C 1.60 BS01 NAP C 1 A14 S16 K17 G18 L19 A38 R39 T40 C64 D65 I66 T67 N88 A89 G90 G91 T139 R157 P183 G184 I185 F186 T188 R190 I191 A16 S18 K19 G20 L21 A40 R41 T42 C66 D67 I68 T69 N90 A91 G92 G93 T141 R159 P185 G186 I187 F188 T190 R192 I193 B2JE32 HHMDLGIAGKSALVCAASKGLGRGCAEALAAEGVNVTIVARTPETLDATAAAIRANAGVDVQAVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHDDWIRALEANMLTPIELIRATIDGMISRGFGRVVNITSSSVKAPIDVLGLSNGARSGLTGFIAGVARKVAPNGVTINNLLPGIFDTDRIAVTFDAAAKAQNISVDEARKQRMATIPARRFGTPDEFGRACAFLCSVHAGYITGQNWLIDGGAYPGTY 5va8 C 1.60 BS02 TCE C 1 S140 S141 I147 L150 S153 R157 G184 T194 R213 S142 S143 I149 L152 S155 R159 G186 T196 R215 B2JE32 HHMDLGIAGKSALVCAASKGLGRGCAEALAAEGVNVTIVARTPETLDATAAAIRANAGVDVQAVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHDDWIRALEANMLTPIELIRATIDGMISRGFGRVVNITSSSVKAPIDVLGLSNGARSGLTGFIAGVARKVAPNGVTINNLLPGIFDTDRIAVTFDAAAKAQNISVDEARKQRMATIPARRFGTPDEFGRACAFLCSVHAGYITGQNWLIDGGAYPGTY 5va8 D 1.60 BS01 NAP D 1 A14 S16 K17 G18 L19 A38 R39 T40 C64 D65 I66 T67 N88 A89 G90 G91 T139 R157 P183 G184 I185 F186 T188 R190 I191 A16 S18 K19 G20 L21 A40 R41 T42 C66 D67 I68 T69 N90 A91 G92 G93 T141 R159 P185 G186 I187 F188 T190 R192 I193 B2JE32 HHMDLGIAGKSALVCAASKGLGRGCAEALAAEGVNVTIVARTPETLDATAAAIRANAGVDVQAVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHDDWIRALEANMLTPIELIRATIDGMISRGFGRVVNITSSSVKAPIDVLGLSNGARSGLTGFIAGVARKVAPNGVTINNLLPGIFDTDRIAVTFDAAAKAQNISVDEARKQRMATIPARRFGTPDEFGRACAFLCSVHAGYITGQNWLIDGGAYPGTY 5va8 D 1.60 BS02 TCE D 1 P92 S140 S141 I147 L150 S153 R157 G184 T194 R213 P94 S142 S143 I149 L152 S155 R159 G186 T196 R215 B2JE32 HHMDLGIAGKSALVCAASKGLGRGCAEALAAEGVNVTIVARTPETLDATAAAIRANAGVDVQAVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHDDWIRALEANMLTPIELIRATIDGMISRGFGRVVNITSSSVKAPIDVLGLSNGARSGLTGFIAGVARKVAPNGVTINNLLPGIFDTDRIAVTFDAAAKAQNISVDEARKQRMATIPARRFGTPDEFGRACAFLCSVHAGYITGQNWLIDGGAYPGTY 5vc7 A 3.90 BS01 ATP A 1 D191 I192 G193 L195 P233 G234 T235 G236 K237 T238 L239 I366 H370 G399 A400 D9 I10 G11 L13 P51 G52 T53 G54 K55 T56 L57 I184 H188 G217 A218 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 A 3.90 BS02 ATP A 2 D468 I469 G470 L472 P510 G511 V512 G513 K514 T515 L516 D567 E568 I644 H648 G672 E676 D286 I287 G288 L290 P328 G329 V330 G331 K332 T333 L334 D385 E386 I462 H466 G490 E494 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 C 3.90 BS01 ATP C 1 D191 I192 G193 L195 P233 G234 T235 G236 K237 T238 L239 I366 H370 G399 A400 D9 I10 G11 L13 P51 G52 T53 G54 K55 T56 L57 I184 H188 G217 A218 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 C 3.90 BS02 ATP C 2 D468 I469 G470 L472 P510 G511 V512 G513 K514 T515 L516 D567 E568 I644 H648 G672 E676 D286 I287 G288 L290 P328 G329 V330 G331 K332 T333 L334 D385 E386 I462 H466 G490 E494 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 D 3.90 BS01 ATP D 1 D191 I192 G193 L195 P233 G234 T235 G236 K237 T238 L239 I366 H370 G399 A400 D9 I10 G11 L13 P51 G52 T53 G54 K55 T56 L57 I184 H188 G217 A218 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 D 3.90 BS02 ATP D 2 D468 I469 G470 L472 P510 G511 V512 G513 K514 T515 L516 D567 E568 I644 H648 G672 E676 D286 I287 G288 L290 P328 G329 V330 G331 K332 T333 L334 D385 E386 I462 H466 G490 E494 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 E 3.90 BS01 ATP E 1 D191 I192 G193 L195 P233 G234 T235 G236 K237 T238 L239 I366 H370 G399 A400 D9 I10 G11 L13 P51 G52 T53 G54 K55 T56 L57 I184 H188 G217 A218 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 E 3.90 BS02 ATP E 2 D468 I469 G470 L472 P510 G511 V512 G513 K514 T515 L516 D567 E568 I644 H648 G672 E676 D286 I287 G288 L290 P328 G329 V330 G331 K332 T333 L334 D385 E386 I462 H466 G490 E494 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 F 3.90 BS01 ATP F 1 D191 I192 G193 L195 P233 G234 T235 G236 K237 T238 L239 I366 H370 G399 A400 D9 I10 G11 L13 P51 G52 T53 G54 K55 T56 L57 I184 H188 G217 A218 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 F 3.90 BS02 ATP F 2 D468 I469 G470 L472 P510 G511 V512 G513 K514 T515 L516 D567 E568 I644 H648 G672 E676 D286 I287 G288 L290 P328 G329 V330 G331 K332 T333 L334 D385 E386 I462 H466 G490 E494 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 G 3.90 BS01 ATP G 1 D191 I192 G193 L195 P233 G234 T235 G236 K237 T238 L239 I366 H370 G399 A400 D9 I10 G11 L13 P51 G52 T53 G54 K55 T56 L57 I184 H188 G217 A218 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vc7 G 3.90 BS02 ATP G 2 D468 I469 G470 L472 P510 G511 V512 G513 K514 T515 L516 D567 E568 I644 H648 G672 E676 D286 I287 G288 L290 P328 G329 V330 G331 K332 T333 L334 D385 E386 I462 H466 G490 E494 O05209 28390173 EVSRISYEDIGGLSEQLGKIREMIELPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANESGANFLSINGPEIMSKYYGQSEQKLREIFSKAEETAPSIIFIDEIDSIAPKREEVQGEVERRVVAQLLTLMDGMKERGHVIVIGATNRIDAIDPALRRPGRFDREIEIGVPDRNGRKEILMIHTRNMPLGMSEEEKNKFLEEMADYTYGFVGADLAALVRESAMNALRRYLPEIDLDKPIPTEILEKMVVTEDDFKNALKSIEPSSLREVMVEVPNVHWDDIGGLEDVKREIKETVELPLLKPDVFKRLGIRPSKGFLLYGPPGVGKTLLAKAVATESNANFISIKGPEVLSKWVGESEKAIREIFKKAKQVAPAIVFLDEIDSIAPRRGTTSDSGVTERIVNQLLTSLDGIEVMNGVVVIGATNRPDIMDPALLRAGRFDKLIYIPPPDKEARLSILKVHTKNMPLAPDVDLNDIAQRTEGYVGADLENLCREAGMNAYRENPDATSVSQKNFLDALKTIRPSVDEEVIKFYRTLSET 5vcn A 3.00 BS01 CA A 1 R26 E44 D56 L57 E59 E91 R26 E44 D56 L57 E59 E91 Q3HWZ5 26026055 TNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCASQHGCHGDTIPRGIEYIQHNGVVQESYYRYVAREQSCRRPNAQRFGISNYCQIYPPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIEEYPYVVIL 5vcn B 3.00 BS01 CA B 1 R26 E44 D56 L57 E59 E91 R26 E44 D56 L57 E59 E91 Q3HWZ5 26026055 TNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCASQHGCHGDTIPRGIEYIQHNGVVQESYYRYVAREQSCRRPNAQRFGISNYCQIYPPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIEEYPYVVIL 5vco E 2.74 BS01 CA E 1 D56 L57 E59 E91 D56 L57 E59 E91 Q3HWZ5 26026055 TNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCASQHGCHGDTIPRGIEYIQHNGVVQESYYRYVAREQSCRRPNAQRFGISNYCQIYPPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIEEYPYVVIL 5vco F 2.74 BS01 CA F 1 R26 E44 D56 L57 E59 E91 R26 E44 D56 L57 E59 E91 Q3HWZ5 26026055 TNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCASQHGCHGDTIPRGIEYIQHNGVVQESYYRYVAREQSCRRPNAQRFGISNYCQIYPPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIEEYPYVVIL 5vg6 A 2.20 BS01 NDP A 1 A78 G79 R96 M106 L151 G152 D153 L154 G155 W172 S173 R174 T175 M204 L205 P206 E210 V232 A233 R234 D258 H282 A284 S285 Y319 A73 G74 R91 M101 L146 G147 D148 L149 G150 W167 S168 R169 T170 M199 L200 P201 E205 V227 A228 R229 D253 H277 A279 S280 Y314 A7IIH0 SGALVFYSAVDIGQDWKSALQAAHPGLDVRIARAGDGHVEGDPEEVRYALVWKPPHGFFARFPNLKLVINLGAGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vg6 B 2.20 BS01 NDP B 1 A78 G79 R96 M106 G150 L151 G152 D153 L154 W172 S173 R174 T175 K177 M204 L205 P206 E210 T211 V232 R234 D258 H282 A284 S285 Y319 A74 G75 R92 M102 G146 L147 G148 D149 L150 W168 S169 R170 T171 K173 M200 L201 P202 E206 T207 V228 R230 D254 H278 A280 S281 Y315 A7IIH0 ASGALVFYSAVDIGQDWKSALQAAHPGLDVRIARAGDGHVEGDPEEVRYALVWKPPHGFFARFPNLKLVINLGAGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vg6 C 2.20 BS01 NDP C 1 A78 G79 R96 M102 M106 G150 L151 G152 D153 L154 W172 S173 R174 T175 K177 M204 L205 P206 V232 A233 R234 D258 H282 A284 S285 Y319 A74 G75 R92 M98 M102 G146 L147 G148 D149 L150 W168 S169 R170 T171 K173 M200 L201 P202 V228 A229 R230 D254 H278 A280 S281 Y315 A7IIH0 ASGALVFYSAVDIGQDWKSALQAAHPGLDVRIARAGDGHVEGDPEEVRYALVWKPPHGFFARFPNLKLVINLGAGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vg6 D 2.20 BS01 NDP D 1 A78 G79 R96 M106 G150 L151 G152 D153 L154 W172 S173 R174 T175 M204 L205 P206 V232 A233 R234 D258 H282 A284 S285 Y319 A71 G72 R89 M99 G143 L144 G145 D146 L147 W165 S166 R167 T168 M193 L194 P195 V221 A222 R223 D247 H271 A273 S274 Y308 A7IIH0 ALVFYSAVDIGQDWKSALQAAHPGLDVRIARAGDGHVEGDPEEVRYALVWKPPHGFFARFPNLKLVINLGAGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vg6 E 2.20 BS01 NDP E 1 A78 G79 R96 M106 G150 L151 G152 D153 L154 W172 S173 R174 T175 M204 L205 P206 E210 T211 V232 A233 R234 D258 H282 A284 S285 Y319 A73 G74 R91 M101 G145 L146 G147 D148 L149 W167 S168 R169 T170 M199 L200 P201 E205 T206 V227 A228 R229 D253 H277 A279 S280 Y314 A7IIH0 SGALVFYSAVDIGQDWKSALQAAHPGLDVRIARAGDGHVEGDPEEVRYALVWKPPHGFFARFPNLKLVINLGAGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vg6 F 2.20 BS01 NDP F 1 A78 G79 R96 M106 G150 L151 G152 D153 L154 G155 W172 S173 R174 T175 M204 L205 P206 T211 V232 A233 R234 D258 H282 A284 Y319 A71 G72 R89 M99 G143 L144 G145 D146 L147 G148 W165 S166 R167 T168 M197 L198 P199 T204 V225 A226 R227 D251 H275 A277 Y312 A7IIH0 ALVFYSAVDIGQDWKSALQAAHPGLDVRIARAGDGHVEGDPEEVRYALVWKPPHGFFARFPNLKLVINLGAGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vg6 G 2.20 BS01 NDP G 1 A78 G79 R96 M106 L151 G152 D153 L154 W172 S173 R174 T175 M204 L205 P206 E210 T211 V232 A233 R234 D258 V259 H282 A284 S285 Y319 A1 G2 R19 M29 L74 G75 D76 L77 W95 S96 R97 T98 M127 L128 P129 E133 T134 V155 A156 R157 D181 V182 H205 A207 S208 Y242 A7IIH0 AGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vg6 H 2.20 BS01 NDP H 1 A78 G79 R96 M106 L151 G152 D153 L154 W172 S173 R174 T175 L205 P206 E210 T211 V232 A233 R234 D258 H282 A284 Y319 A1 G2 R19 M29 L74 G75 D76 L77 W95 S96 R97 T98 L128 P129 E133 T134 V155 A156 R157 D181 H205 A207 Y242 A7IIH0 AGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vg6 I 2.20 BS01 NDP I 1 A78 G79 R96 M106 L151 G152 D153 L154 W172 S173 R174 T175 K177 M204 L205 P206 V232 A233 R234 D258 H282 A284 S285 Y319 A74 G75 R92 M102 L147 G148 D149 L150 W168 S169 R170 T171 K173 M200 L201 P202 V228 A229 R230 D254 H278 A280 S281 Y315 A7IIH0 ASGALVFYSAVDIGQDWKSALQAAHPGLDVRIARAGDGHVEGDPEEVRYALVWKPPHGFFARFPNLKLVINLGAGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vg6 J 2.20 BS01 NDP J 1 A78 G79 R96 M106 L151 G152 D153 L154 G155 W172 S173 R174 T175 M204 L205 P206 E210 V232 A233 R234 D258 H282 A284 S285 Y319 A74 G75 R92 M102 L147 G148 D149 L150 G151 W168 S169 R170 T171 M200 L201 P202 E206 V228 A229 R230 D254 H278 A280 S281 Y315 A7IIH0 ASGALVFYSAVDIGQDWKSALQAAHPGLDVRIARAGDGHVEGDPEEVRYALVWKPPHGFFARFPNLKLVINLGAGVDALVARDDLPDVPVTRLSDPNMSQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAIPRTAAPQIVENIRRIEAGEPVLNQVDPRRGY 5vgm A 1.95 BS01 ZN A 1 K98 H135 H173 K96 H124 H162 3.5.2.3 A0A0H6AFA4 AMTTLTITRPDDWHVHLRDGDVLADTVRDISRYNGRALIMPNTVPPVTTTEMALAYRERIMAAQHFEPLMALYLTDNTSPEEIRKAKASGKVVAAKLYPGVTSAKNIYPVLQAMQEVGMLLLVHGEVTTHEVDIFDREKTFLDTVLAPIVNDFPQLKIVLEHITTADAVTFVQQAGDNVAATITAHHLLFNRNHMLVGGIRPHFYCLPILKRATHQHALVAAATSGSKKFFLGTDSAPHAKGRKEAACGCAGSYTAHAALELYAEVFEKEGKLENLEAFASFNGPDFYGLPRNQETVTLTKQAWPVAESMPFGSDIVVPIRAGENIEWTVK 5vgm A 1.95 BS02 ZN A 2 H13 H15 K98 D246 H14 H16 K96 D235 3.5.2.3 A0A0H6AFA4 AMTTLTITRPDDWHVHLRDGDVLADTVRDISRYNGRALIMPNTVPPVTTTEMALAYRERIMAAQHFEPLMALYLTDNTSPEEIRKAKASGKVVAAKLYPGVTSAKNIYPVLQAMQEVGMLLLVHGEVTTHEVDIFDREKTFLDTVLAPIVNDFPQLKIVLEHITTADAVTFVQQAGDNVAATITAHHLLFNRNHMLVGGIRPHFYCLPILKRATHQHALVAAATSGSKKFFLGTDSAPHAKGRKEAACGCAGSYTAHAALELYAEVFEKEGKLENLEAFASFNGPDFYGLPRNQETVTLTKQAWPVAESMPFGSDIVVPIRAGENIEWTVK 5vgm B 1.95 BS01 ZN B 1 K98 H135 H173 K101 H135 H173 3.5.2.3 A0A0H6AFA4 SNAMTTLTITRPDDWHVHLRDGDVLADTVRDISRYNGRALIMPNTVPPVTTTEMALAYRERIMAAQPQAHFEPLMALYLTDNTSPEEIRKAKASGKVVAAKLYPAGNSDSGVTSAKNIYPVLQAMQEVGMLLLVHGEVTTHEVDIFDREKTFLDTVLAPIVNDFPQLKIVLEHITTADAVTFVQQAGDNVAATITAHHLLFNRNHMLVGGIRPHFYCLPILKRATHQHALVAAATSGSKKFFLGTDSAPHAKGRKEAACGCAGSYTAHAALELYAEVFEKEGKLENLEAFASFNGPDFYGLPRNQETVTLTKQAWPVAESMPFGSDIVVPIRAGENIEWTVK 5vgm B 1.95 BS02 ZN B 2 H13 H15 K98 D246 H16 H18 K101 D246 3.5.2.3 A0A0H6AFA4 SNAMTTLTITRPDDWHVHLRDGDVLADTVRDISRYNGRALIMPNTVPPVTTTEMALAYRERIMAAQPQAHFEPLMALYLTDNTSPEEIRKAKASGKVVAAKLYPAGNSDSGVTSAKNIYPVLQAMQEVGMLLLVHGEVTTHEVDIFDREKTFLDTVLAPIVNDFPQLKIVLEHITTADAVTFVQQAGDNVAATITAHHLLFNRNHMLVGGIRPHFYCLPILKRATHQHALVAAATSGSKKFFLGTDSAPHAKGRKEAACGCAGSYTAHAALELYAEVFEKEGKLENLEAFASFNGPDFYGLPRNQETVTLTKQAWPVAESMPFGSDIVVPIRAGENIEWTVK 5vi8 D 2.76 BS01 NUC O 1 Y36 R37 Y33 R34 2.7.7.6 A0QS66 28067618 VNFFDELRIGLATADDIRNWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDDEMRHNELSTLEAEMAVEKKAVEDQRDADLEARAQKLEADLAELEAEGAKSDVRRKVRDSGEREMRQLRDRAQRELDRLDEIWNTFTKLAPKQLIVDEVLYRELQDRYGEYFTGAMGAESIKKLIENFDIDAEAESLREVIRSGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGKPLAMPRLDMVTGLYYLTTLVEGATGEYQAATKDAPEQGVYSSPAEAIMAMDRGALSVRAKIKVRLTELRPPTDLEAQLFENGWKPGDAWTAETTLGRVMFNELLPKSYPFVNEQMHKKVQARIINDLAERFPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPQKQEILERHEAEADAIERKYQRGALNHTERNESLVKIWQDATEEVGKALEEFYPADNPIITIVKSGATGNLTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERGPDIRDAHVETSAFARTLATDAVDANGNVIIERGHDLGDPAIDALLAAGITTVKVRSVLTCTSATGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTGGLPRVQELFEARVPRNKAPIADVAGRVRLEESDKFFKITIVPDDGGEEVVYDKLSKRQRLRVIGVLSDGDHVEVGDQLMEGAADPHEVLRVQGPREVQIHLVKEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLTERAEFEAENRRVVAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGISRYRNIQVQPTEEARAAA 5vi8 D 2.76 BS02 ZN D 1 C890 C967 C974 C977 C887 C961 C968 C971 2.7.7.6 A0QS66 28067618 VNFFDELRIGLATADDIRNWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDDEMRHNELSTLEAEMAVEKKAVEDQRDADLEARAQKLEADLAELEAEGAKSDVRRKVRDSGEREMRQLRDRAQRELDRLDEIWNTFTKLAPKQLIVDEVLYRELQDRYGEYFTGAMGAESIKKLIENFDIDAEAESLREVIRSGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGKPLAMPRLDMVTGLYYLTTLVEGATGEYQAATKDAPEQGVYSSPAEAIMAMDRGALSVRAKIKVRLTELRPPTDLEAQLFENGWKPGDAWTAETTLGRVMFNELLPKSYPFVNEQMHKKVQARIINDLAERFPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPQKQEILERHEAEADAIERKYQRGALNHTERNESLVKIWQDATEEVGKALEEFYPADNPIITIVKSGATGNLTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERGPDIRDAHVETSAFARTLATDAVDANGNVIIERGHDLGDPAIDALLAAGITTVKVRSVLTCTSATGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTGGLPRVQELFEARVPRNKAPIADVAGRVRLEESDKFFKITIVPDDGGEEVVYDKLSKRQRLRVIGVLSDGDHVEVGDQLMEGAADPHEVLRVQGPREVQIHLVKEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLTERAEFEAENRRVVAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGISRYRNIQVQPTEEARAAA 5vi8 D 2.76 BS03 ZN D 2 C60 C62 C75 C78 C57 C59 C72 C75 2.7.7.6 A0QS66 28067618 VNFFDELRIGLATADDIRNWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDDEMRHNELSTLEAEMAVEKKAVEDQRDADLEARAQKLEADLAELEAEGAKSDVRRKVRDSGEREMRQLRDRAQRELDRLDEIWNTFTKLAPKQLIVDEVLYRELQDRYGEYFTGAMGAESIKKLIENFDIDAEAESLREVIRSGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGKPLAMPRLDMVTGLYYLTTLVEGATGEYQAATKDAPEQGVYSSPAEAIMAMDRGALSVRAKIKVRLTELRPPTDLEAQLFENGWKPGDAWTAETTLGRVMFNELLPKSYPFVNEQMHKKVQARIINDLAERFPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPQKQEILERHEAEADAIERKYQRGALNHTERNESLVKIWQDATEEVGKALEEFYPADNPIITIVKSGATGNLTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERGPDIRDAHVETSAFARTLATDAVDANGNVIIERGHDLGDPAIDALLAAGITTVKVRSVLTCTSATGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTGGLPRVQELFEARVPRNKAPIADVAGRVRLEESDKFFKITIVPDDGGEEVVYDKLSKRQRLRVIGVLSDGDHVEVGDQLMEGAADPHEVLRVQGPREVQIHLVKEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLTERAEFEAENRRVVAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGISRYRNIQVQPTEEARAAA 5vi8 D 2.76 BS04 MG D 1 D535 D537 D539 D532 D534 D536 2.7.7.6 A0QS66 28067618 VNFFDELRIGLATADDIRNWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDDEMRHNELSTLEAEMAVEKKAVEDQRDADLEARAQKLEADLAELEAEGAKSDVRRKVRDSGEREMRQLRDRAQRELDRLDEIWNTFTKLAPKQLIVDEVLYRELQDRYGEYFTGAMGAESIKKLIENFDIDAEAESLREVIRSGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGKPLAMPRLDMVTGLYYLTTLVEGATGEYQAATKDAPEQGVYSSPAEAIMAMDRGALSVRAKIKVRLTELRPPTDLEAQLFENGWKPGDAWTAETTLGRVMFNELLPKSYPFVNEQMHKKVQARIINDLAERFPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPQKQEILERHEAEADAIERKYQRGALNHTERNESLVKIWQDATEEVGKALEEFYPADNPIITIVKSGATGNLTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERGPDIRDAHVETSAFARTLATDAVDANGNVIIERGHDLGDPAIDALLAAGITTVKVRSVLTCTSATGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTGGLPRVQELFEARVPRNKAPIADVAGRVRLEESDKFFKITIVPDDGGEEVVYDKLSKRQRLRVIGVLSDGDHVEVGDQLMEGAADPHEVLRVQGPREVQIHLVKEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLTERAEFEAENRRVVAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGISRYRNIQVQPTEEARAAA 5vi8 F 2.76 BS01 NUC O 1 L178 A236 N237 R239 L240 R268 K272 F273 D274 K277 Y279 K280 S282 T283 Y284 T286 W287 W288 Q291 R295 R305 P307 V308 H309 R408 V436 T437 E439 R440 Q443 L33 A91 N92 R94 L95 R123 K127 F128 D129 K132 Y134 K135 S137 T138 Y139 T141 W142 W143 Q146 R150 R160 P162 V163 H164 R261 V289 T290 E292 R293 Q296 A0QW02 28067618 AKKAPAKRAAKSAAAKAADSVRAYLKQIGKVALLNAEEEVELAKRIEAGLYATQKLAELAEKGEKLPVQQRRDMQWICRDGDRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDDSQLGDFIEDSEAVVAVDAVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD 5vi8 F 2.76 BS02 NUC P 1 R295 E312 R319 R416 T426 L427 R438 E439 R442 R150 E167 R174 R269 T279 L280 R291 E292 R295 A0QW02 28067618 AKKAPAKRAAKSAAAKAADSVRAYLKQIGKVALLNAEEEVELAKRIEAGLYATQKLAELAEKGEKLPVQQRRDMQWICRDGDRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDDSQLGDFIEDSEAVVAVDAVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD 5vi8 T 2.76 BS01 NUC O 1 V258 R259 N262 N288 V8 R9 N12 N38 2.7.7.6 A0QSL8 28067618 IDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIKLHQ 5vi8 T 2.76 BS02 NUC P 1 R259 N288 F289 G290 Q291 K292 S293 R9 N38 F39 G40 Q41 K42 S43 2.7.7.6 A0QSL8 28067618 IDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIKLHQ 5vih A 2.40 BS01 GLY A 1 F92 P124 L125 T126 R131 S179 S180 D224 F250 F78 P107 L108 T109 R114 S162 S163 D207 F233 P35439 RLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGTRITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVR 5vih B 2.40 BS01 5DZ B 1 H88 S114 T116 R121 T134 G135 I136 G172 S173 T174 Y214 D215 A241 T243 Y245 H81 S107 T109 R114 T127 G128 I129 G165 S166 T167 Y207 D208 A234 T236 Y238 Q00959 DNHLSIVTLEEAPFVIVEDIDPLTCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGICH 5vii A 1.95 BS01 GLY A 1 F92 P124 T126 R131 S179 S180 W223 D224 F250 F78 P107 T109 R114 S162 S163 W206 D207 F233 P35439 RLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGTRITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVR 5vii B 1.95 BS01 5DY B 1 H88 S114 T116 N118 R121 G135 I136 G172 S173 T174 Y214 D215 A241 T243 Y245 H81 S107 T109 N111 R114 G128 I129 G165 S166 T167 Y207 D208 A234 T236 Y238 G3V9C5 DNHLSIVTLEEAPFVIVEDIDTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC 5vij A 2.11 BS01 GLY A 1 F92 P124 L125 T126 R131 S179 S180 W223 D224 F78 P107 L108 T109 R114 S162 S163 W206 D207 P35439 RLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGTRITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRY 5vij B 2.11 BS01 5DX B 1 H88 S114 T116 R121 G135 I136 G172 S173 T174 Y214 D215 A241 T243 Y245 H83 S109 T111 R116 G130 I131 G167 S168 T169 Y209 D210 A236 T238 Y240 Q00959 DNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGICH 5vir A 1.70 BS01 9CG A 1 W184 Y185 W163 Y164 2.7.7.18 B1MMZ4 RRRLGVMGGTFDPIHNGHLVAASEVADRFALDEVIFVPTGQPWQKQGRKVSPAEHRYLMTVIATASNPRFTVSRADIDRGGATYTVDTLTDLRTAHPDADLYFITGADALASILSWENWEQLFTLAKFIGVSRPGGLSLVEVPALAISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYS 5vir A 1.70 BS02 NAP A 1 M12 G13 G14 T15 F16 H20 H23 T44 K50 T88 Y89 T90 F108 T110 G111 W121 E122 V136 S169 S170 M7 G8 G9 T10 F11 H15 H18 T39 K45 T83 Y84 T85 F103 T105 G106 W116 E117 V131 S148 S149 2.7.7.18 B1MMZ4 RRRLGVMGGTFDPIHNGHLVAASEVADRFALDEVIFVPTGQPWQKQGRKVSPAEHRYLMTVIATASNPRFTVSRADIDRGGATYTVDTLTDLRTAHPDADLYFITGADALASILSWENWEQLFTLAKFIGVSRPGGLSLVEVPALAISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYS 5vir A 1.70 BS03 9CG B 1 S71 N72 P73 S66 N67 P68 2.7.7.18 B1MMZ4 RRRLGVMGGTFDPIHNGHLVAASEVADRFALDEVIFVPTGQPWQKQGRKVSPAEHRYLMTVIATASNPRFTVSRADIDRGGATYTVDTLTDLRTAHPDADLYFITGADALASILSWENWEQLFTLAKFIGVSRPGGLSLVEVPALAISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYS 5vir B 1.70 BS01 9CG A 1 S71 N72 P73 S65 N66 P67 2.7.7.18 B1MMZ4 RRRLGVMGGTFDPIHNGHLVAASEVADRFALDEVIFVPTGQPWQKQRKVSPAEHRYLMTVIATASNPRFTVSRADIDRGGATYTVDTLTDLRTAHPDADLYFITGADALASILSWENWEQLFTLAKFIGVSRPGYELSSDHIAHAELPPDGLSLVEVPALAISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYS 5vir B 1.70 BS02 9CG B 1 W184 Y185 W178 Y179 2.7.7.18 B1MMZ4 RRRLGVMGGTFDPIHNGHLVAASEVADRFALDEVIFVPTGQPWQKQRKVSPAEHRYLMTVIATASNPRFTVSRADIDRGGATYTVDTLTDLRTAHPDADLYFITGADALASILSWENWEQLFTLAKFIGVSRPGYELSSDHIAHAELPPDGLSLVEVPALAISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYS 5vir B 1.70 BS03 NAP B 1 M12 G13 G14 T15 H20 H23 T44 W48 T88 T90 F108 T110 G111 A114 S117 I118 E122 V136 R138 S169 S170 M7 G8 G9 T10 H15 H18 T39 W43 T82 T84 F102 T104 G105 A108 S111 I112 E116 V130 R132 S163 S164 2.7.7.18 B1MMZ4 RRRLGVMGGTFDPIHNGHLVAASEVADRFALDEVIFVPTGQPWQKQRKVSPAEHRYLMTVIATASNPRFTVSRADIDRGGATYTVDTLTDLRTAHPDADLYFITGADALASILSWENWEQLFTLAKFIGVSRPGYELSSDHIAHAELPPDGLSLVEVPALAISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYS 5wro A 2.02 BS01 CO A 1 N221 H225 N160 H164 4.2.1.11 P15007 28368282 GAMDPEFTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ 5wvw A 1.80 BS01 NUC C 1 K24 W26 A27 A28 A29 P30 K31 R33 L40 Y49 R51 K22 W24 A25 A26 A27 P28 K29 R31 L38 Y47 R49 Q97ZE3 28377493 SGKKPVKVKTPAGKEAELVPEKVWAAAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvw A 1.80 BS02 NUC D 1 R33 K34 G35 V36 I38 R51 H52 K53 R31 K32 G33 V34 I36 R49 H50 K51 Q97ZE3 28377493 SGKKPVKVKTPAGKEAELVPEKVWAAAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvw B 1.80 BS01 NUC E 1 K24 W26 A27 A28 A29 P30 K31 R33 L40 Y49 R51 K22 W24 A25 A26 A27 P28 K29 R31 L38 Y47 R49 Q97ZE3 28377493 SGKKPVKVKTPAGKEAELVPEKVWAAAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvw B 1.80 BS02 NUC F 1 R33 K34 G35 V36 I38 R51 H52 K53 R31 K32 G33 V34 I36 R49 H50 K51 Q97ZE3 28377493 SGKKPVKVKTPAGKEAELVPEKVWAAAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvy A 2.00 BS01 NUC C 1 K24 W26 A27 V28 A29 P30 K31 R33 L40 Y49 R51 K23 W25 A26 V27 A28 P29 K30 R32 L39 Y48 R50 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAVAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvy A 2.00 BS02 NUC D 1 R33 G35 V36 I38 R51 H52 K53 R32 G34 V35 I37 R50 H51 K52 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAVAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvy B 2.00 BS01 NUC E 1 K24 W26 A27 V28 A29 P30 K31 R33 L40 Y49 R51 K23 W25 A26 V27 A28 P29 K30 R32 L39 Y48 R50 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAVAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvy B 2.00 BS02 NUC F 1 R33 G35 V36 I38 R51 H52 K53 R32 G34 V35 I37 R50 H51 K52 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAVAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvz A 2.30 BS01 NUC C 1 K24 W26 A27 F28 A29 P30 K31 L40 Y49 R51 K23 W25 A26 F27 A28 P29 K30 L39 Y48 R50 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAFAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvz A 2.30 BS02 NUC D 1 R33 V36 R51 H52 K53 R32 V35 R50 H51 K52 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAFAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvz B 2.30 BS01 NUC E 1 K24 W26 A27 F28 A29 P30 K31 R33 L40 Y49 R51 K23 W25 A26 F27 A28 P29 K30 R32 L39 Y48 R50 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAFAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wvz B 2.30 BS02 NUC F 1 R33 V36 R51 H52 K53 R32 V35 R50 H51 K52 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAFAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wwc A 1.90 BS01 NUC C 1 K24 W26 A27 M28 A29 Y49 R51 K20 W22 A23 M24 A25 Y45 R47 Q97ZE3 28377493 KKPVKVKTPAGKEAELVPEKVWAMAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wwc A 1.90 BS02 NUC D 1 M28 V36 I38 F50 R51 H52 K53 M24 V32 I34 F46 R47 H48 K49 Q97ZE3 28377493 KKPVKVKTPAGKEAELVPEKVWAMAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wwc B 1.90 BS01 NUC E 1 K24 W26 A27 M28 A29 P30 L40 K48 Y49 R51 K23 W25 A26 M27 A28 P29 L39 K47 Y48 R50 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAMAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wwc B 1.90 BS02 NUC F 1 M28 R33 V36 R51 K53 M27 R32 V35 R50 K52 Q97ZE3 28377493 SSGKKPVKVKTPAGKEAELVPEKVWAMAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 5wx3 A 1.80 BS01 COA A 1 K48 R51 M52 K55 S56 C157 L200 D201 V204 I208 L261 S262 R263 V265 P266 G299 P301 N330 K40 R43 M44 K47 S48 C149 L192 D193 V196 I200 L253 S254 R255 V257 P258 G291 P293 N322 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADLDTTTERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFTPLGINDWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMWGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAI 5wx3 B 1.80 BS01 COA B 1 K48 R51 M52 K55 S56 C157 L200 V204 I248 L261 S262 R263 V265 G299 P301 N330 K40 R43 M44 K47 S48 C149 L192 V196 I235 L248 S249 R250 V252 G279 P281 N310 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMWGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAI 5wx3 C 1.80 BS01 COA C 1 K48 R51 M52 K55 C157 L200 V204 I208 F209 I248 L261 S262 R263 V265 P266 G299 G300 P301 A302 R305 N330 K40 R43 M44 K47 C149 L192 V196 I200 F201 I240 L253 S254 R255 V257 P258 G269 G270 P271 A272 R275 N300 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADLDTTTERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMWGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAI 5wx3 D 1.80 BS01 COA D 1 K48 R51 M52 K55 S56 C157 V204 I208 L261 S262 R263 P266 G299 P301 N330 K40 R43 M44 K47 S48 C149 V196 I200 L248 S249 R250 P253 G286 P288 N317 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFTPLGINDWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMWGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAI 5wx6 A 1.80 BS01 COA A 1 K48 R51 M52 K55 S56 C157 V204 I248 L261 S262 R263 V265 P266 H297 G299 P301 N330 K40 R43 M44 K47 S48 C149 V196 I232 L245 S246 R247 V249 P250 H276 G278 P280 N309 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGAPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFTDWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMQGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAIN 5wx6 B 1.80 BS01 COA B 1 K48 R51 M52 K55 S56 C157 L200 V204 L261 S262 R263 P266 G299 G300 N330 K40 R43 M44 K47 S48 C149 L192 V196 L253 S254 R255 P258 G291 G292 N322 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADLDTTTERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFTPLGINDWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMQGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAIN 5wx6 C 1.80 BS01 COA C 1 K48 R51 M52 K55 C157 L200 V204 L261 S262 R263 P266 G299 P301 A302 N330 K40 R43 M44 K47 C149 L192 V196 L253 S254 R255 P258 G284 P286 A287 N315 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADLDTTTERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMQGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAI 5wx6 D 1.80 BS01 COA D 1 R51 M52 K55 S56 C157 L200 D201 V204 L261 S262 R263 G299 P301 F367 R49 M50 K53 S54 C155 L198 D199 V202 L259 S260 R261 G291 P293 F359 28411241 SKVESRQAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADLDTTTERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFDWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMQGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAI 5wx7 A 1.90 BS01 COA A 1 K48 R51 M52 K55 S56 C157 L200 V204 L261 S262 R263 H297 G299 P301 N330 K40 R43 M44 K47 S48 C149 L192 V196 L253 S254 R255 H283 G285 P287 N316 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADLDTTTERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFDWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMGGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAIN 5wx7 B 1.90 BS01 COA B 1 K48 R51 M52 K55 S56 C157 V204 L261 S262 R263 P266 H297 G299 G300 P301 N330 F367 K40 R43 M44 K47 S48 C149 V196 L253 S254 R255 P258 H282 G284 G285 P286 N315 F352 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADLDTTTERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMGGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAI 5wx7 C 1.90 BS01 COA C 1 K48 R51 M52 K55 S56 C157 L200 V204 I208 I248 L261 S262 R263 P266 H297 G299 P301 N330 K40 R43 M44 K47 S48 C149 L192 V196 I200 I240 L253 S254 R255 P258 H289 G291 P293 N322 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADLDTTTERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFTPLGINDWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMGGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAIN 5wx7 D 1.90 BS01 COA D 1 K48 R51 M52 K55 C157 V204 I248 L261 S262 R263 P266 H297 G299 P301 A302 N330 K40 R43 M44 K47 C149 V196 I240 L253 S254 R255 P258 H282 G284 P286 A287 N315 28411241 QAAVLAIATANPPNIFYQADYPDFYFRVTKSEHMTQLKDKFKRMCEKSMIRKRHMYLTEDVIKENPNIGILNAPSFNARQEIMVEEVPKLGKEAALKAIKEWGQPLSKLTHLIFCTSSGVNMPSADYHLAKIMGLPPYVQRTMIYQQGCFAGATALRLAKDIAENNGGHTRILIVCVELMVVCFQAPSDTYLDLLVGNAIFSDGAAAAIVGADLDTTTERPIFNIVSANQTTIPDSEDGIVGHIREMGMKYYLSRTVPQVIGNNIVQCCRDTFWNSMFYIVHPGGPAVLRMMEEKLGLSKERMRASWHVLSEYGNMGGPSVLFILDEMRNKSMEEGKSTTGEGLEWGVMFGFGPGLTVETVVLRSVAI 5x7g A 2.20 BS01 CA A 1 E425 E427 T444 G447 D542 E386 E388 T405 G408 D503 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7g A 2.20 BS02 CA A 2 D665 Q667 N670 D626 Q628 N631 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS01 CA A 1 E425 E427 T444 G447 D542 E386 E388 T405 G408 D503 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS02 CA A 2 Y389 D665 Q667 Y350 D626 Q628 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS03 GLC A 1 F208 R210 Y582 P584 F169 R171 Y543 P545 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS04 GLC A 2 P500 E513 T514 W515 P461 E474 T475 W476 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS05 GLC A 3 E513 H580 Y582 N585 E474 H541 Y543 N546 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS06 GLC A 4 F208 Y582 F169 Y543 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS07 GLC A 5 Y183 D184 M186 H189 F208 Y234 M236 M276 Y582 Y144 D145 M147 H150 F169 Y195 M197 M237 Y543 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS08 GLC A 6 Y183 Y234 M236 D309 Q310 M311 N355 E381 E581 Y144 Y195 M197 D270 Q271 M272 N316 E342 E542 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS09 GLC A 7 H440 N540 H401 N501 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS10 GLC A 8 A453 A538 A414 A499 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS11 GLC A 9 N480 S481 N441 S442 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS12 GLC A 10 Y519 D574 Y480 D535 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5x7h A 2.60 BS13 GLC A 11 E154 E159 E163 Y470 E573 D574 R586 E115 E120 E124 Y431 E534 D535 R547 2.4.1.248 G9MBW2 28385816 MASGDVERVYTDKSRYDPGDPVTITAQVRNTDSIAWTGTVQLRIAHLEDQVHTASQTVTIGGGQTEDVQFTWTSPATDFKGYLADIDAGALGSGTTAIDVSSDFARYPRYGYVSEFHPDETAAESAAKIDELAQDYKINAWQFYDWMWRHETMIKRTGSAIDSTWIDLFNREISWQTIQNQIDAVHDQNGAAMAYAMIYAAREDYESYGVDSEWGIYQDPNHLQQLDVDFGNNSTYMYLFNPANTDWQSFIHAQYLDAINTAGFDGIHVDQMGQRNNVYDYWGNPLNFPATFTPFINEAKSTLTANNSDKDRITYNIVDGTVDGWAANEVSGGADVDFLYSEIWHLSDSYIQLKDYIDSLKANSGNKAVVLAAYMNYRENIGDRYEAESAALTNTATNNNHSGYTGSGFVDQFADPGDAVTFSITVPEEGYYSLVFRFANNSGFTATRNLYVDSAFEIELPFQNQPSWSAWSHETWHQVYLTPGTHTIKLAYDAGNVGAINLDSLTLGTFDPHSIRLANAMMAASGATHIELGEDSQMLAHEYYPNRSKSMRSELKEALKQHYNFITAYENLLFDPDVVDNDSGSQFVNLDMVSASGDASPNTVWHQVKRTPEYNIVHFINLANNDNQWRNSANPPTLHTNIATKVYVSPDETISGVYLASPDHDDNRTQSLAYTTGTDIHGDYVAFTLPSLEYWSMVYM 5xdf A 2.00 BS01 HSE A 1 K99 N150 G151 T152 Y178 E180 D186 D191 K195 G288 K96 N147 G148 T149 Y175 E177 D183 D188 K192 G285 1.1.1.3 Q5SL04 MEALKIALLGGGTVGSAFYNLVLERAEELSAFGVVPRFLGVLVRDPRAIPQELLRAEPFDLLEADLVVEAMGGVEAPLRLVLPALEAGIPLITANKALLAEAWESLRPFAEEGLIYHEASVMAGTPALSFLETLRGSELLELHGILNGTTLYILQEMEKGRTYAEALLEAQRLGYAEADPTLDVEGIDAAHKLTLLARLLVDPGFPFAEVEAQGIARLTPEVLQKAEARGERVRLVASLFGEGGRWRAAVAPRRLPQDHPLARARGNALWVRARPLGEAFVTGPGAGGGATASGLFADLLRFLSGAPGHLPAPRARPPLEEGS 5xdf B 2.00 BS01 HSE B 1 K99 N150 G151 T152 Y178 E180 D186 K195 G288 A289 K99 N150 G151 T152 Y178 E180 D186 K195 G288 A289 1.1.1.3 Q5SL04 MEALKIALLGGGTVGSAFYNLVLERAEELSAFGVVPRFLGVLVRDPRKPRAIPQELLRAEPFDLLEADLVVEAMGGVEAPLRLVLPALEAGIPLITANKALLAEAWESLRPFAEEGLIYHEASVMAGTPALSFLETLRGSELLELHGILNGTTLYILQEMEKGRTYAEALLEAQRLGYAEADPTLDVEGIDAAHKLTLLARLLVDPGFPFAEVEAQGIARLTPEVLQKAEARGERVRLVASLFGEGGRWRAAVAPRRLPQDHPLARARGNALWVRARPLGEAFVTGPGAGGGATASGLFADLLRFLSGAPGHLPAPRARPPLEEGSWPGV