5ayk A 2.25 BS01 1PS A 1 Y112 E113 S114 Y79 E80 S81 1.8.4.- QNFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRKKYDKYGEKGLEDNQGGQYESWSYYRYDFGIYDDDPEIITLERREFDAAVNSGELWFVNFYSPGSSHSHDLAPTWREFAKEVDGLLRIGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAAVKYNGDRSKESLVAFAMQHVRSTVTELSTGNFVNAIETAFAAGVGWLITFCSKGEDCLTSQTRLRLSGMLDGLVNVGWVDCDAQDSLCKSLDSTTAYFPPGATLNDREKSSVLFLNSLDAKEIYMEIIHNLPDFELLSANQLEDRLAHHRWLVFFHFGKNNDPELKKLKTLLKNEHIQVVRFDCSSAPGICSDLYVFQPSLAVFKGQGTKEYEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPASDKEPWLVDFFAPWSPPSRALLPELRKASTLLYGQLKVGTLDCTIHEGLCNMYNIQAYPTTVVFNQSSIHEYEGHHSAEQILEFIEDLRNPSVVSLTPSTFNELVKQRKHDEVWMVDFYSPWSHPSQVLMPEWKRMARTLTGLINVGSVDCQQYHSFCTQENVQRYPEIRFYPQKSSKAYQYHSYNGWNRDAYSLRSWGLGFLPQASIDLTPQTFNEKVLQGKTHWVVDFYAPWSGPSQNFAPEFELLARMIKGKVRAGKVDCQAYPQTCQKAGIKAYPSVKLYQYERAKKSIWEEQINSRDAKTIAALIYGKLETLQ 5ayl A 2.40 BS01 1PS A 1 E761 Q762 N764 S765 E721 Q722 N724 S725 1.8.4.- DQNFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNAHGDFLKINRAYEVLKDEDLRKKYDKYGEKGLEDQYESWSYYRYDFGIYDDDPEIITLERREFDAAVNSGELWFVNFYSPGSSHSHDLAPTWREFAKEVDGLLRIGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAAVKYNGDRSKESLVAFAMQHVRSTVTELSTGNFVNAIETAFAAGVGWLITFCSKGEDCLTSQTRLRLSGMLDGLVNVGWVDCDAQDSLCKSLDTTASTTAYFPPGATLNDREKSSVLFLNSLDAKEIYMEIIHNLPDFELLSANQLEDRLAHHRWLVFFHFGKNENANDPELKKLKTLLKNEHIQVVRFDCSSAPGICSDLYVFQPSLAVFKGQGTKEYEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPASDKEPWLVDFFAPWSPPSRALLPELRKASTLLYGQLKVGTLDCTIHEGLCNMYNIQAYPTTVVFNQSSIHEYEGHHSAEQILEFIEDLRNPSVVSLTPSTFNELVKQRKHDEVWMVDFYSPWSHPSQVLMPEWKRMARTLTGLINVGSVDCQQYHSFCTQENVQRYPEIRFYPQKSAYQYHSYNGWNRDAYSLRSWGLGFLPQASIDLTPQTFNEKVLQGKTHWVVDFYAPWSGPSQNFAPEFELLARMIKGKVRAGKVDCQAYPQTCQKAGIKAYPSVKLYQYERAKKSIWEEQINSRDAKTIAALIYGKLETLQ 5b1l A 2.35 BS01 NUC I 1 Y41 H42 P43 T45 R63 R72 R83 F84 Q85 R116 V117 T118 M120 Y4 H5 P6 T8 R26 R35 R46 F47 Q48 R79 V80 T81 M83 28099840 PHRYHPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACESYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5b1l D 2.35 BS01 NUC I 1 G32 R33 E35 Y42 G53 I54 S55 S56 R86 S87 T88 G1 R2 E4 Y11 G22 I23 S24 S25 R55 S56 T57 28099840 GRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSS 5b1l G 2.35 BS02 NUC J 1 K15 T16 R17 R20 R29 R32 R42 K74 R77 K1 T2 R3 R6 R15 R18 R28 K60 R63 28099840 KTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 5b1m A 2.34 BS01 NUC I 1 R40 Y41 R42 P43 T45 R72 R83 F84 Q85 R116 V117 T118 M120 R3 Y4 R5 P6 T8 R35 R46 F47 Q48 R79 V80 T81 M83 28099840 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5b1m C 2.34 BS02 NUC J 1 R11 T16 R29 R42 V43 G44 A45 K75 T76 R77 K118 R1 T6 R19 R32 V33 G34 A35 K65 T66 R67 K108 28099840 RAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 5b3r A 2.00 BS01 ZN A 1 H95 H97 H157 H71 H73 H133 3.5.2.6 27381398 LPDLKIEKLEKGVYVHTSFEGWGVVTKHGLVVLVKNDAYLIDTPITAKDTEKLVNWFIEHGYRIKGSISTHFHGDSTAGIEWLNSQSISTYASELTNELLKKDNKVQATNSFSGVSYSLIKNKIEVFYPGPGHTQDNVVVWLPEKKILFGGCFVKPDGLGNLGDANLEAWPKSAKILMSKYGKAKLVVSSHSEIGNASLLQRTWEQAVKGLNES 5b3r A 2.00 BS02 ZN A 2 D99 C176 H215 D75 C152 H191 3.5.2.6 27381398 LPDLKIEKLEKGVYVHTSFEGWGVVTKHGLVVLVKNDAYLIDTPITAKDTEKLVNWFIEHGYRIKGSISTHFHGDSTAGIEWLNSQSISTYASELTNELLKKDNKVQATNSFSGVSYSLIKNKIEVFYPGPGHTQDNVVVWLPEKKILFGGCFVKPDGLGNLGDANLEAWPKSAKILMSKYGKAKLVVSSHSEIGNASLLQRTWEQAVKGLNES 5b3u B 2.70 BS01 NAP B 1 G17 T18 G19 Y20 A21 N43 S44 N47 A78 T79 I80 N81 H84 E101 Y102 E128 R167 W168 Q174 G10 T11 G12 Y13 A14 N36 S37 N40 A71 T72 I73 N74 H77 E94 Y95 E121 R160 W161 Q167 ATPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGY 5b3v B 2.59 BS01 NAP B 1 G17 T18 G19 Y20 A21 N43 S44 N47 A78 T79 I80 N81 H84 E101 Y102 E128 I130 R167 W168 F284 G9 T10 G11 Y12 A13 N35 S36 N39 A70 T71 I72 N73 H76 E93 Y94 E120 I122 R159 W160 F276 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGY 5b3v B 2.59 BS02 BLA B 1 M159 R185 Y235 K237 R246 R280 M151 R177 Y227 K229 R238 R272 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGY 5b3v B 2.59 BS03 BLA B 2 Y20 Y102 E131 S184 R185 R188 L283 Y12 Y94 E123 S176 R177 R180 L275 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGY 5b3v A 2.59 BS01 NAP A 1 T18 G19 Y20 A21 N43 S44 N47 A78 T79 I80 N81 L83 H84 E101 Y102 E128 R167 W168 F284 T10 G11 Y12 A13 N35 S36 N39 A70 T71 I72 N73 L75 H76 E93 Y94 E120 R159 W160 F276 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGYK 5b3v A 2.59 BS02 BLA A 1 Y20 Y102 I130 A182 S184 R185 R188 R280 Y12 Y94 I122 A174 S176 R177 R180 R272 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGYK 5b3v A 2.59 BS03 BLA A 2 M159 Q161 T169 Y170 R185 K237 R246 R280 M151 Q153 T161 Y162 R177 K229 R238 R272 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGYK 5b3v C 2.59 BS02 BLA C 1 Y20 Y102 I130 E131 A182 S184 R185 R188 L283 Y12 Y94 I122 E123 A174 S176 R177 R180 L275 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGY 5b3v C 2.59 BS03 BLA C 2 T157 M159 Q161 T169 R185 K237 R246 T149 M151 Q153 T161 R177 K229 R238 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGY 5b3v D 2.59 BS02 BLA D 1 Y20 Y102 I130 R167 S184 R185 R188 R280 Y12 Y94 I122 R159 S176 R177 R180 R272 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGY 5b3v D 2.59 BS03 BLA D 2 M159 Q161 T169 R185 K237 R246 R280 M151 Q153 T161 R177 K229 R238 R272 TPVRVGIVGTGYAAQRRAEVFRGDRRSQLVSFWGNSEANTAKFADTFGVRPQQSWQALINDPEIDLVLIATINQLHGAIAEAALQAGKHVVLEYPLALTYAMGKKLQQLAREKGKLLHVEHIELLGGVHQAIRQNLGKIGEVFYARYSTIMGQNPAPQRWTYHHQQFGFPLVAALSRISRFTDLFGTVQQVDAQCRFWDQPNPEYFRACLATAYLQFNNGLKAEVIYGKGEVFHQNERIFTLHGDRGTLIFVGETGRLIQGQTETEITVGSRRGLFRQDTEAVLDYLTTGKPLYVDLEASLYALEVADLCAQACGY 5ff7 A 2.09 BS02 G3H A 1 Q28 R29 G30 A31 R34 T94 G95 Q27 R28 G29 A30 R33 T93 G94 4.1.2.40 ITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM 5ff7 B 2.09 BS01 G3P B 1 D27 Q28 K205 S249 L275 G277 R278 D26 Q27 K204 S248 L274 G276 R277 4.1.2.40 ITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM 5ff7 B 2.09 BS02 CA B 1 N312 D316 N311 D315 4.1.2.40 ITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM 5fgn A 2.75 BS01 ZN A 1 E240 T280 D452 H453 E233 T273 D445 H446 PKLGSSALIAFLSLYSSLVLNYAFFAKVVELHPFNGTGADIFLYTMPVVLFFLSNFVFHVIALPFVHKVLIPLILVISAAVSYQEIFFNIYFNKSMLNNVLQTTAAESARLITPGYVLWIVCLGVLPALAYIAVKVKYRVWYKEFLTRLVLAAVSFLCALGIAMLQYQDYASFFRNNKSVTHLIVPSNFIGAGVSKYKDWKRSNIPYTQLDMAVVQNRPAGSLRRFVVLVVGETTRAANWGLNGYSRQTTPLLAARGDEIVNFPQVRSCGTSTAHSLPCMFSTFDRTDYDEIKAEHQDNLLDIVQRAGVEVTWLENDSGCKGVCGKVPNTDVTSLNLPEYCRNGECLDNILLTKFDEVLNKNDKDAVLILHTIGSHGPTYYERYTEAERKFTPTCDTNEINKCTRATLVNTYDNTVLYVDQFIDKVIRKLENRDDLESVVHYVSDHGESLGENGMYLHAAPYAIAPSGQTHIPMVMWFSKAFRQHGGIDFQCLKQKAAENEYSHDHYFSTVLGLMDISNSQTYRKEMDILAACRRP 5g1z A 1.50 BS01 NHW A 1 Y28 K29 F30 W31 N94 Y95 V96 N161 F162 L163 C164 V165 R170 S171 K172 R173 L174 A175 P176 T183 I186 N187 W192 Q193 A194 Y196 T197 A198 L202 Y393 Y3 K4 F5 W6 N69 Y70 V71 N136 F137 L138 C139 V140 R145 S146 K147 R148 L149 A150 P151 T158 I161 N162 W167 Q168 A169 Y171 T172 A173 L177 Y368 2.3.1.97 IDYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSSLNSRLTMSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5g1z C 1.50 BS02 U53 C 1 V96 E97 D98 F103 F105 F226 S319 L330 A332 Y334 V363 N365 V70 E71 D72 F77 F79 F200 S279 L290 A292 Y294 V323 N325 2.3.1.97 DYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5g20 A 1.52 BS02 MYA A 1 H12 A13 F14 W15 N79 Y80 V81 I166 F168 L169 C170 V171 R176 E177 K178 R179 L180 A181 P182 T189 V192 N193 W198 Q199 A200 Y202 T203 L208 Y404 H2 A3 F4 W5 N69 Y70 V71 I156 F158 L159 C160 V161 R166 E167 K168 R169 L170 A171 P172 T179 V182 N183 W188 Q189 A190 Y192 T193 L198 Y394 2.3.1.97 AHAFWSTQPVPQTEDETEKIVFAGPMDEPKTVADIPEEPYPIASTFEWWTPNMEAADDIHAIYELLRDNYVEDDDSMFRFNYSEEFLQWALCPPNYIPDWHVAVRRKADKKLLAFIAGVPVTLRMGTPKYMKVKAQEKGEGEEAAKYDEPRHICEINFLCVHKQLREKRLAPILIKEATRRVNRTNVWQAVYTAGVLLPTPYASGQYFHRSLNPEKLVEIRFSGIPAQYQKFQNPMAMLKRNYQLPSAPKNSGLREMKPSDVPQVRRILMNYLDSFDVGPVFSDAEISHYLLPRDGVVFTYVVENDKKVTDFFSFYRIPSTVIGNSNYNLLNAAYVHYYAATSIPLHQLILDLLIVAHSRGFDVCNMVEILDNRSFVEQLKFGAGDGHLRYYFYNWAYPKIKPSQVALVML 5g20 A 1.52 BS03 QBY A 1 V81 E82 D83 F88 F90 G205 Y217 H219 R231 S330 L341 Y345 N376 V71 E72 D73 F78 F80 G195 Y207 H209 R221 S320 L331 Y335 N366 2.3.1.97 AHAFWSTQPVPQTEDETEKIVFAGPMDEPKTVADIPEEPYPIASTFEWWTPNMEAADDIHAIYELLRDNYVEDDDSMFRFNYSEEFLQWALCPPNYIPDWHVAVRRKADKKLLAFIAGVPVTLRMGTPKYMKVKAQEKGEGEEAAKYDEPRHICEINFLCVHKQLREKRLAPILIKEATRRVNRTNVWQAVYTAGVLLPTPYASGQYFHRSLNPEKLVEIRFSGIPAQYQKFQNPMAMLKRNYQLPSAPKNSGLREMKPSDVPQVRRILMNYLDSFDVGPVFSDAEISHYLLPRDGVVFTYVVENDKKVTDFFSFYRIPSTVIGNSNYNLLNAAYVHYYAATSIPLHQLILDLLIVAHSRGFDVCNMVEILDNRSFVEQLKFGAGDGHLRYYFYNWAYPKIKPSQVALVML 5g21 A 1.50 BS03 YN4 A 1 V81 E82 D83 F88 F90 N167 T203 Y217 F232 S330 L341 Y345 N376 L399 L421 V71 E72 D73 F78 F80 N157 T193 Y207 F222 S320 L331 Y335 N366 L389 L411 2.3.1.97 AHAFWSTQPVPQTEDETEKIVFAGPMDEPKTVADIPEEPYPIASTFEWWTPNMEAADDIHAIYELLRDNYVEDDDSMFRFNYSEEFLQWALCPPNYIPDWHVAVRRKADKKLLAFIAGVPVTLRMGTPKYMKVKAQEKGEGEEAAKYDEPRHICEINFLCVHKQLREKRLAPILIKEATRRVNRTNVWQAVYTAGVLLPTPYASGQYFHRSLNPEKLVEIRFSGIPAQYQKFQNPMAMLKRNYQLPSAPKNSGLREMKPSDVPQVRRILMNYLDSFDVGPVFSDAEISHYLLPRDGVVFTYVVENDKKVTDFFSFYRIPSTVIGNSNYNLLNAAYVHYYAATSIPLHQLILDLLIVAHSRGFDVCNMVEILDNRSFVEQLKFGAGDGHLRYYFYNWAYPKIKPSQVALVML 5g22 A 2.32 BS02 YN4 A 1 V96 E97 D98 F103 F105 T197 Y211 H213 F226 S319 L330 Y334 N365 L388 L410 V71 E72 D73 F78 F80 T172 Y186 H188 F201 S294 L305 Y309 N340 L363 L385 2.3.1.97 IDYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSSLNSRLTMSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5g22 B 2.32 BS02 YN4 B 1 V96 E97 D98 F103 F105 Y211 H213 L221 F226 S319 Y334 N365 L388 L410 V71 E72 D73 F78 F80 Y186 H188 L196 F201 S294 Y309 N340 L363 L385 2.3.1.97 IDYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSSLNSRLTMSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5g22 C 2.32 BS01 NHW C 1 Y28 K29 F30 W31 N94 Y95 V96 N161 F162 L163 C164 V165 R170 S171 R173 L174 A175 P176 I179 T183 I186 W192 Q193 A194 Y196 T197 A198 L202 Y393 Y2 K3 F4 W5 N68 Y69 V70 N135 F136 L137 C138 V139 R144 S145 R147 L148 A149 P150 I153 T157 I160 W166 Q167 A168 Y170 T171 A172 L176 Y352 2.3.1.97 DYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5g22 C 2.32 BS02 YN4 C 1 V96 E97 D98 F103 F105 Y107 T197 G199 Y211 H213 L221 F226 S319 L330 Y334 N365 L388 L410 V70 E71 D72 F77 F79 Y81 T171 G173 Y185 H187 L195 F200 S278 L289 Y293 N324 L347 L369 2.3.1.97 DYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5g26 A 2.42 BS01 97N A 1 Y235 L259 A261 Q263 Y274 I278 Y27 L51 A53 Q55 Y66 I70 27976759 HYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPANMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLIYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKSWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYK 5g26 A 2.42 BS02 97N A 2 G292 G293 F330 Y354 G84 G85 F122 Y146 27976759 HYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPANMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLIYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKSWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYK 5g26 A 2.42 BS03 97M A 1 F230 L232 V246 A257 F22 L24 V38 A49 27976759 HYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPANMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLIYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKSWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYK 5g26 A 2.42 BS04 97N A 3 L217 Q218 S219 D224 G225 L344 V377 Y379 I389 Y403 L9 Q10 S11 D16 G17 L136 V169 Y171 I181 Y195 27976759 HYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPANMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLIYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKSWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYK 5g2s A 2.84 BS01 MOO A 1 P295 G296 R369 S400 P274 G275 R344 S375 2.10.1.1 27803248 EMIPTEEALRIVFGVSKRLPPVIVSLYEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGPGEYPVITESRAGNDVTVTPGTVAYVTTGGPIPDGADAVVQVEDTKVITESKRVKILIQTKKGTDIRRVGCDIEKDATVLTTGERIGASEIGLLATAGVTMVKVYPMPIVAILSTGDELVEPTAGTLGRGQIRDSNRAMLVAAVMQQQCKVVDLGIVRDDRKELEKVLDEAVSSGVDIILTSGGVSMGDRDFVKPLLEEKGKVYFSKVLMKPGKPLTFAEIRAKPLGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPHPLRVRLRLQEPIKSDPIRPEFHRAIIKWKDNDGSGTPGFVAESTGHQMSSRLLSMRSANALLELPATGNVLSAGSSVSAIIVSDISAF 5g3j A 2.40 BS01 III B 1 I572 V575 K579 R585 L589 M593 Q597 E751 M752 E755 N759 I44 V47 K51 R57 L61 M65 Q69 E223 M224 E227 N231 28043796 TPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQMIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ 5g3j A 2.40 BS02 E7T A 1 M560 L563 N564 L566 G567 Q570 W600 M601 M604 R611 F623 Q642 M646 Y735 T739 F749 L753 M32 L35 N36 L38 G39 Q42 W72 M73 M76 R83 F95 Q114 M118 Y207 T211 F221 L225 28043796 TPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQMIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ 5g5w A 2.20 BS02 R8C A 1 M560 L563 N564 L566 G567 Q570 M601 M604 A607 L608 R611 F623 Q642 M646 Y735 C736 T739 L753 M31 L34 N35 L37 G38 Q41 M72 M75 A78 L79 R82 F94 Q113 M117 Y206 C207 T210 L224 27810243 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQMIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ 5glb A 1.60 BS01 CB4 A 1 C69 S70 Y105 Y129 S130 N132 N170 T226 G246 T247 C48 S49 Y84 Y108 S109 N111 N149 T195 G215 T216 3.5.2.6 27827433 GSHMRNVAAEQQLRELESTFDGRLGFVALDTATGARIAHRADERFPFCSTFKTMLSAAVLARSAGDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGPQAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRAQLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTMRSRNAQARDDVIASAARIAARAFV 5gld A 1.70 BS01 CB4 A 1 C69 S70 V103 R104 S130 N132 G256 T257 G258 D260 C48 S49 V82 R83 S109 N111 G208 T209 G210 D211 3.5.2.6 27827433 GSHMRNVAAEQQLRELESTFDGRLGFVALDTATGARIAHRADERFPFCSTFKTMLSAAVLARSAGDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGPQAVTAYARSIGDATFRLDRRLPGDERDTTTPAAMAASVRRLLVGDALGTAQRAQLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTMRSRNAQARDDVIASAARIAARAFV 5gre A 2.65 BS01 MG A 1 D230 D234 D217 D221 1.1.1.41 28098230 VQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQWMIPSEAKESMDKNKMGLKGPLKTPPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDL 5gre A 2.65 BS02 CIT B 1 K173 N175 I176 K160 N162 I163 1.1.1.41 28098230 VQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQWMIPSEAKESMDKNKMGLKGPLKTPPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDL 5gre B 2.65 BS01 ADP B 1 I26 N78 P252 R272 N273 T274 G275 K276 I278 N285 D326 I12 N64 P238 R258 N259 T260 G261 K262 I264 N271 D312 1.1.1.41 28098230 RHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVI 5gre B 2.65 BS02 MG B 1 N78 R272 N64 R258 1.1.1.41 28098230 RHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVI 5gre B 2.65 BS03 CIT B 1 N78 T81 S91 N93 R97 R128 Y135 N239 R272 N64 T67 S77 N79 R83 R114 Y121 N225 R258 1.1.1.41 28098230 RHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVI 5grf A 2.50 BS01 CIT B 1 K173 N175 K160 N162 1.1.1.41 28098230 VQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQWMIPSEAKESMDKNKMGLKGPLKTPPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGNAKCSDFTEEICRRVKDL 5grf B 2.50 BS02 ADP B 1 I26 P252 R272 N273 T274 G275 K276 I278 N285 D326 I12 P238 R258 N259 T260 G261 K262 I264 N271 D312 1.1.1.41 28098230 RHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLAIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVING 5grl B 2.79 BS02 ICT B 1 N78 S91 N93 R97 R128 Y135 N239 R272 N64 S77 N79 R83 R114 Y121 N225 R258 1.1.1.41 28098230 RHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVING 5gro B 2.00 BS01 BUA B 1 R39 G43 L44 K87 R38 G42 L43 K86 6.1.1.23 RSHFCTEISEKDVGKIVKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKALEVRSEFVLVAKGKVRLRGAGLENPKLKTGKIEIVLEELIIENKS 5gsu C 3.10 BS01 NUC I 1 K15 S16 K17 R19 R34 R44 R79 K1 S2 K3 R5 R20 R30 R65 27992841 KSKSRSSRAGLQFPVGRIHRLLRKGNYAERIGAGAPVYLAAVLEYLTAEILELAGNASRDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPK 5gsu C 3.10 BS02 NUC J 1 S16 R31 R44 I45 G46 A47 K77 T78 R79 S2 R17 R30 I31 G32 A33 K63 T64 R65 27992841 KSKSRSSRAGLQFPVGRIHRLLRKGNYAERIGAGAPVYLAAVLEYLTAEILELAGNASRDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPK 5gsu D 3.10 BS01 NUC I 1 K28 T30 R31 G51 I52 S53 S54 R84 S85 T86 K123 K2 T4 R5 G25 I26 S27 S28 R58 S59 T60 K97 27992841 RKRTRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 5gsu D 3.10 BS03 MN D 1 Q45 V46 Q19 V20 27992841 RKRTRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 5gsu H 3.10 BS02 NUC J 1 T30 Y40 I52 S54 R84 S85 T86 T1 Y11 I23 S25 R55 S56 T57 27992841 TRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 5gt0 A 2.82 BS01 NUC I 1 R40 Y41 R42 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 R4 Y5 R6 T9 R27 R36 R47 F48 Q49 S50 R80 V81 T82 27992841 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 5gt0 E 2.82 BS03 MN E 1 E73 D77 E37 D41 27992841 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 5gt0 C 2.82 BS01 NUC I 1 S14 K15 R17 R20 G28 R32 R42 R77 S1 K2 R4 R7 G15 R19 R29 R64 27992841 SKSRSSRAGLQFPVGRIHRLLRKGNYAERIGAGAPVYLAAVLEYLTAEILELAGNASRDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKK 5gt0 G 2.82 BS01 NUC I 1 K13 R29 R42 I43 G44 A45 K75 R77 K1 R17 R30 I31 G32 A33 K63 R65 27992841 KSKSRSSRAGLQFPVGRIHRLLRKGNYAERIGAGAPVYLAAVLEYLTAEILELAGNASRDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPK 5gt0 D 2.82 BS01 NUC I 1 R29 K30 S32 R33 Y42 G53 I54 S55 S56 R86 S87 T88 R2 K3 S5 R6 Y15 G26 I27 S28 S29 R59 S60 T61 27992841 KRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 5gt0 D 2.82 BS02 NUC J 1 K28 R29 R31 R33 K34 E35 S36 V39 Y40 K1 R2 R4 R6 K7 E8 S9 V12 Y13 27992841 KRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 5gt3 A 2.91 BS01 NUC I 1 Y41 R42 P43 T45 R72 R83 F84 Q85 V117 T118 M120 Y4 R5 P6 T8 R35 R46 F47 Q48 V80 T81 M83 27992841 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 5gt3 C 2.91 BS01 NUC I 1 A14 K15 T16 R17 R32 R77 A2 K3 T4 R5 R20 R65 27992841 KAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPK 5gt3 D 2.91 BS01 NUC I 1 R31 T32 R33 Y42 G53 I54 S55 S56 R86 S87 T88 K125 R1 T2 R3 Y12 G23 I24 S25 S26 R56 S57 T58 K95 27992841 RTRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 5gt3 G 2.91 BS02 NUC J 1 T16 R17 R29 R32 R77 T1 R2 R14 R17 R62 27992841 TRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPK 5gt3 H 2.91 BS02 NUC J 1 K34 S55 S56 R86 S87 T88 K1 S22 S23 R53 S54 T55 27992841 KESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 5gt3 H 2.91 BS03 MN G 1 S90 S91 S57 S58 27992841 KESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 5gzz A 2.39 BS01 JAA A 1 T121 F125 T166 Y170 F220 V222 H328 G331 W336 T115 F119 T160 Y164 F214 V216 H322 G325 W330 6.3.2.- TFDMNRVIDEFDEMTRNAHQVQKQTLKEILLKNQSAIYLQNCGLNGNATDPEEAFKSMVPLVTDVELEPYIKRMVDGDTSPILTGHPVPAISLSSGTSQGRPKFIPFTDELMENTLQLFRTAFAFRNRDFPIDDNGKALQFIFSSKQYISTGGVPVGTATTNVYRNPNFKAGMKSITSPSCSPDEVIFSPDVHQALYCHLLSGILFRDQVQYVFAVFAHGLVHAFRTFEQVWEEIVTDIKDGVLSNRITVPSVRTAMSKLLTPNPELAETIRTKCMSLSNWYGLIPALFPNAKYVYGIMTGSMEPYVPKLRHYAGDLPLVSHDYGSSEGWIAANVTPRLSPEEATFAVIPNLGYFEFLPVSETGEGEEKPVGLTQVKIGEEYEVVITNYAGLYRYRLGDVVKVIGFYNNTPQLKFICRRNLILSINIDKNTERDLQLSVESAAKRLSEEKIEVIDFSSYIDVSTDPGHYAIFWEISGETNEDVLQDCCNCLDRAFIDAGYVSSRKCKTIGALELRVVAKGTFRKIQEHFLGLGSSAGQFKMPRCVKPSNAKVLQILCENVVSSYFSTAF 5gzz B 2.39 BS01 GSH B 1 W8 L13 W41 N54 L55 Q67 W8 L13 W41 N54 L55 Q67 2.5.1.18 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHP 5gzz C 2.39 BS01 GSH C 1 W8 L13 N54 L55 Q67 W8 L13 N54 L55 Q67 2.5.1.18 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHP 5gzz D 2.39 BS01 GSH D 1 L13 K45 N54 L55 P56 Q67 S68 L13 K45 N54 L55 P56 Q67 S68 2.5.1.18 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHP 5gzz E 2.39 BS01 GSH E 1 L13 N54 L55 P56 Q67 S68 L13 N54 L55 P56 Q67 S68 2.5.1.18 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHP 5gzz F 2.39 BS01 GSH F 1 W8 W41 N54 L55 Q67 S68 Y104 W8 W41 N54 L55 Q67 S68 Y104 2.5.1.18 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHP 5gzz G 2.39 BS01 GSH F 1 D101 Y104 D101 Y104 2.5.1.18 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHP 5gzz G 2.39 BS02 GSH G 1 L13 W41 N54 L55 Q67 S68 L13 W41 N54 L55 Q67 S68 2.5.1.18 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHP 5h7n A 1.85 BS01 MTT A 1 D15 K16 K43 E45 E46 W63 A64 D66 R67 E112 E154 P155 Y156 W231 W341 Y342 R345 D14 K15 K42 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 Y341 R344 28112203 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAARAAALCRLSTYLEELEAVELKKFKLYLGTATEEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLV 5h7n B 1.85 BS01 MTT B 1 D15 K16 E45 E46 W63 A64 D66 R67 E112 E154 P155 Y156 W231 W341 Y342 R345 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 Y341 R344 28112203 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAARAAALCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVR 5h7q A 1.45 BS01 MAL A 1 D15 K16 W63 A64 D66 R67 E112 E154 P155 Y156 F157 W231 W341 R345 D14 K15 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 W340 R344 28112203 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAARAFAAAEYKKILLLKGFELMDDYHFTSIKSLLAYDLGLTTKMQEEYNRIKITDLMEKKFQGVACLDKLIELAKDMPSLKNLVNNLRKEKSKVAKKIKTQE 5h9y A 1.97 BS01 BGC A 1 E194 S195 T238 E185 S186 T229 3.2.1.39 ADFTQGADVSGNNVTLWFKSSVNTTWVDVHYKVNSGVQQNVRMSFNAGAARFEHTILTAAQAEIEYFFTYNNGVPAYDTTTFTYRTNSIYSIPASSIPQPSEGGVSLKVMNGTGGAYTDDQIYWGVIGINPVNGKWSYLDLAGRLLPISSDLNNAPGHLTKDGINYANIYHKISDANWVNLPKIESGRLFLSVGSPLYMKTFDDGFAGPDLNNPTDPNLNIIFDFVAFTVDKDGYHGNTTRVDQFGFPIQHRLVNLAGNYDRTVGELESETRSGLFAKYVNEVPYEFKSLGTLQAPYRILSPMKGPFQEGGAYENYFAGYSSISTQDILLGVGEASNPEVCAALNRHVYTEPDNWNRVDQYYQAAPANYYAKFWHDHSIDGLAYGFCYDDVNGQAAYLEVGDPKGLIVRVGW 5h9y A 1.97 BS02 BGC A 2 S195 G196 R197 A236 F237 S186 G187 R188 A227 F228 3.2.1.39 ADFTQGADVSGNNVTLWFKSSVNTTWVDVHYKVNSGVQQNVRMSFNAGAARFEHTILTAAQAEIEYFFTYNNGVPAYDTTTFTYRTNSIYSIPASSIPQPSEGGVSLKVMNGTGGAYTDDQIYWGVIGINPVNGKWSYLDLAGRLLPISSDLNNAPGHLTKDGINYANIYHKISDANWVNLPKIESGRLFLSVGSPLYMKTFDDGFAGPDLNNPTDPNLNIIFDFVAFTVDKDGYHGNTTRVDQFGFPIQHRLVNLAGNYDRTVGELESETRSGLFAKYVNEVPYEFKSLGTLQAPYRILSPMKGPFQEGGAYENYFAGYSSISTQDILLGVGEASNPEVCAALNRHVYTEPDNWNRVDQYYQAAPANYYAKFWHDHSIDGLAYGFCYDDVNGQAAYLEVGDPKGLIVRVGW 5h9y A 1.97 BS03 BGC A 3 F234 V251 D252 F225 V242 D243 3.2.1.39 ADFTQGADVSGNNVTLWFKSSVNTTWVDVHYKVNSGVQQNVRMSFNAGAARFEHTILTAAQAEIEYFFTYNNGVPAYDTTTFTYRTNSIYSIPASSIPQPSEGGVSLKVMNGTGGAYTDDQIYWGVIGINPVNGKWSYLDLAGRLLPISSDLNNAPGHLTKDGINYANIYHKISDANWVNLPKIESGRLFLSVGSPLYMKTFDDGFAGPDLNNPTDPNLNIIFDFVAFTVDKDGYHGNTTRVDQFGFPIQHRLVNLAGNYDRTVGELESETRSGLFAKYVNEVPYEFKSLGTLQAPYRILSPMKGPFQEGGAYENYFAGYSSISTQDILLGVGEASNPEVCAALNRHVYTEPDNWNRVDQYYQAAPANYYAKFWHDHSIDGLAYGFCYDDVNGQAAYLEVGDPKGLIVRVGW 5h9y A 1.97 BS04 BGC A 4 L339 C396 L330 C387 3.2.1.39 ADFTQGADVSGNNVTLWFKSSVNTTWVDVHYKVNSGVQQNVRMSFNAGAARFEHTILTAAQAEIEYFFTYNNGVPAYDTTTFTYRTNSIYSIPASSIPQPSEGGVSLKVMNGTGGAYTDDQIYWGVIGINPVNGKWSYLDLAGRLLPISSDLNNAPGHLTKDGINYANIYHKISDANWVNLPKIESGRLFLSVGSPLYMKTFDDGFAGPDLNNPTDPNLNIIFDFVAFTVDKDGYHGNTTRVDQFGFPIQHRLVNLAGNYDRTVGELESETRSGLFAKYVNEVPYEFKSLGTLQAPYRILSPMKGPFQEGGAYENYFAGYSSISTQDILLGVGEASNPEVCAALNRHVYTEPDNWNRVDQYYQAAPANYYAKFWHDHSIDGLAYGFCYDDVNGQAAYLEVGDPKGLIVRVGW 5h9y A 1.97 BS05 BGC A 5 T238 D240 H245 T229 D231 H236 3.2.1.39 ADFTQGADVSGNNVTLWFKSSVNTTWVDVHYKVNSGVQQNVRMSFNAGAARFEHTILTAAQAEIEYFFTYNNGVPAYDTTTFTYRTNSIYSIPASSIPQPSEGGVSLKVMNGTGGAYTDDQIYWGVIGINPVNGKWSYLDLAGRLLPISSDLNNAPGHLTKDGINYANIYHKISDANWVNLPKIESGRLFLSVGSPLYMKTFDDGFAGPDLNNPTDPNLNIIFDFVAFTVDKDGYHGNTTRVDQFGFPIQHRLVNLAGNYDRTVGELESETRSGLFAKYVNEVPYEFKSLGTLQAPYRILSPMKGPFQEGGAYENYFAGYSSISTQDILLGVGEASNPEVCAALNRHVYTEPDNWNRVDQYYQAAPANYYAKFWHDHSIDGLAYGFCYDDVNGQAAYLEVGDPKGLIVRVGW 5h9y A 1.97 BS06 BGC A 6 A236 F237 T238 H245 N247 A227 F228 T229 H236 N238 3.2.1.39 ADFTQGADVSGNNVTLWFKSSVNTTWVDVHYKVNSGVQQNVRMSFNAGAARFEHTILTAAQAEIEYFFTYNNGVPAYDTTTFTYRTNSIYSIPASSIPQPSEGGVSLKVMNGTGGAYTDDQIYWGVIGINPVNGKWSYLDLAGRLLPISSDLNNAPGHLTKDGINYANIYHKISDANWVNLPKIESGRLFLSVGSPLYMKTFDDGFAGPDLNNPTDPNLNIIFDFVAFTVDKDGYHGNTTRVDQFGFPIQHRLVNLAGNYDRTVGELESETRSGLFAKYVNEVPYEFKSLGTLQAPYRILSPMKGPFQEGGAYENYFAGYSSISTQDILLGVGEASNPEVCAALNRHVYTEPDNWNRVDQYYQAAPANYYAKFWHDHSIDGLAYGFCYDDVNGQAAYLEVGDPKGLIVRVGW 5h9y A 1.97 BS07 BGC A 7 T249 V251 Y393 C396 T240 V242 Y384 C387 3.2.1.39 ADFTQGADVSGNNVTLWFKSSVNTTWVDVHYKVNSGVQQNVRMSFNAGAARFEHTILTAAQAEIEYFFTYNNGVPAYDTTTFTYRTNSIYSIPASSIPQPSEGGVSLKVMNGTGGAYTDDQIYWGVIGINPVNGKWSYLDLAGRLLPISSDLNNAPGHLTKDGINYANIYHKISDANWVNLPKIESGRLFLSVGSPLYMKTFDDGFAGPDLNNPTDPNLNIIFDFVAFTVDKDGYHGNTTRVDQFGFPIQHRLVNLAGNYDRTVGELESETRSGLFAKYVNEVPYEFKSLGTLQAPYRILSPMKGPFQEGGAYENYFAGYSSISTQDILLGVGEASNPEVCAALNRHVYTEPDNWNRVDQYYQAAPANYYAKFWHDHSIDGLAYGFCYDDVNGQAAYLEVGDPKGLIVRVGW 5h9y A 1.97 BS08 BGC A 8 L339 G340 C396 Y397 L330 G331 C387 Y388 3.2.1.39 ADFTQGADVSGNNVTLWFKSSVNTTWVDVHYKVNSGVQQNVRMSFNAGAARFEHTILTAAQAEIEYFFTYNNGVPAYDTTTFTYRTNSIYSIPASSIPQPSEGGVSLKVMNGTGGAYTDDQIYWGVIGINPVNGKWSYLDLAGRLLPISSDLNNAPGHLTKDGINYANIYHKISDANWVNLPKIESGRLFLSVGSPLYMKTFDDGFAGPDLNNPTDPNLNIIFDFVAFTVDKDGYHGNTTRVDQFGFPIQHRLVNLAGNYDRTVGELESETRSGLFAKYVNEVPYEFKSLGTLQAPYRILSPMKGPFQEGGAYENYFAGYSSISTQDILLGVGEASNPEVCAALNRHVYTEPDNWNRVDQYYQAAPANYYAKFWHDHSIDGLAYGFCYDDVNGQAAYLEVGDPKGLIVRVGW 5hxf A 1.39 BS01 AG7 A 1 Q23 F26 H41 E72 Y123 L126 N127 L128 S129 K131 T143 K144 A145 G146 C148 H162 I163 G164 G165 N166 F171 Q23 F26 H41 E72 Y123 L126 N127 L128 S129 K131 T143 K144 A145 G146 C148 H162 I163 G164 G165 N166 F171 MGPSLDFALSLLRRNIRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWVEHKLVNVLDAVELVDEQGVDLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKVVGIHIGGNGRQGFCAGLKRSYFAS 5i02 A 1.25 BS02 PK2 A 1 L68 G69 N70 D102 Y106 D156 C158 I201 Q203 G229 G230 L231 A232 M260 G261 D280 V282 L46 G47 N48 D80 Y84 D127 C129 I172 Q174 G200 G201 L202 A203 M231 G232 D251 V253 2.4.2.29 DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAAGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFARN 5i03 A 1.73 BS02 NEZ A 1 L68 D102 Y106 D156 C158 I201 Q203 G229 G230 L231 A232 M260 G261 D280 V282 L53 D87 Y91 D131 C133 I176 Q178 G204 G205 L206 A207 M235 G236 D255 V257 2.4.2.29 DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSTKQSEEGVTFHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFAR 5i06 A 1.36 BS02 E89 A 1 L68 D102 Y106 Q107 D156 C158 I201 Q203 G229 G230 L231 A232 Y258 M260 G261 D280 L50 D84 Y88 Q89 D129 C131 I174 Q176 G202 G203 L204 A205 Y231 M233 G234 D253 2.4.2.29 DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKAGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSTKQSEEGVTFKHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFAR 5i07 A 1.89 BS02 NE8 A 1 D102 Y106 D156 C158 I201 Q203 G229 G230 L231 A232 Y258 M260 G261 D280 D84 Y88 D138 C140 I183 Q185 G211 G212 L213 A214 Y240 M242 G243 D262 2.4.2.29 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSHLDGSRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFARNS 5i07 B 1.89 BS02 NE8 B 1 L68 D102 S103 Y106 D156 C158 I201 Q203 G229 G230 L231 A232 Y258 M260 G261 D280 L50 D84 S85 Y88 D138 C140 I183 Q185 G211 G212 L213 A214 Y240 M242 G243 D262 2.4.2.29 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSHLDGSRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFARNS 5i1v A 1.84 BS01 FAD A 1 D23 V59 R60 S61 G62 G63 H64 C65 F69 V70 L81 A100 G122 F123 C124 V127 G128 G130 G131 H132 G137 Y138 G191 G192 G195 I197 I328 Y446 N448 Y449 D21 V57 R58 S59 G60 G61 H62 C63 F67 V68 L79 A98 G120 F121 C122 V125 G126 G128 G129 H130 G135 Y136 G189 G190 G193 I195 I326 Y444 N446 Y447 TRAAVTVKPDDHRYDLLARADNYRFVAQPEYFRLPYSTAQVVEAVSEAVAAGKRLTVRSGGHCGEAFVASPDVDVIVDLSSMSHVGYDEERGAFEVEAGATVGQIYRVLYKNYGVTFPGGFCMGVGAGGHISGGGYGPLSRLLGLTVDYLHAVEVVVVDAEGVVSTVVATREEDDPNRDLWWAHTGGGGGNFGVITRYWLRSPDAVGDAPEEALPRPPASFHVARVSWSWAELTEADYVRLVSNFLDWQLRNCTVDSPNIGLYALLECFHRSAGHLAMHAQIPVDVPDAEERMSWFLAELNEGVAVAPSLTRRRLPWLATSQLLAIPDVGPGAIGVRRKVKSADLRGPHTREQLAAAYRHLSRADYHCPSAAMEYIAYGGRVNTVDPAATAVPRGASLKTFYMVAWTDPDEDEEHLRWIREIYRDIHSATGGVPTPDEVNTGAYINYPDIDLADPEWNTSGVPWHTIYYGDNYPRLQEIKSRWDPRNVFRHAFSIRPR 5i1w A 2.15 BS02 67L A 1 H64 G66 F123 C124 F403 M405 N448 Y449 H62 G64 F121 C122 F401 M403 N446 Y447 TRAAVTVKPDDHRYDLLARADNYRFVAQPEYFRLPYSTAQVVEAVSEAVAAGKRLTVRSGGHCGEAFVASPDVDVIVDLSSMSHVGYDEERGAFEVEAGATVGQIYRVLYKNYGVTFPGGFCMGVGAGGHISGGGYGPLSRLLGLTVDYLHAVEVVVVDAEGVVSTVVATREEDDPNRDLWWAHTGGGGGNFGVITRYWLRSPDAVGDAPEEALPRPPASFHVARVSWSWAELTEADYVRLVSNFLDWQLRNCTVDSPNIGLYALLECFHRSAGHLAMHAQIPVDVPDAEERMSWFLAELNEGVAVAPSLTRRRLPWLATSQLLAIPDVGPGAIGVRRKVKSADLRGPHTREQLAAAYRHLSRADYHCPSAAMEYIAYGGRVNTVDPAATAVPRGASLKTFYMVAWTDPDEDEEHLRWIREIYRDIHSATGGVPTPDEVNTGAYINYPDIDLADPEWNTSGVPWHTIYYGDNYPRLQEIKSRWDPRNVFRHAFSIRPR 5i1w B 2.15 BS01 FAD B 1 D23 V59 R60 S61 G62 G63 H64 C65 V70 L81 A100 G122 F123 C124 V127 G128 G130 G131 H132 G137 Y138 G191 G192 G195 I197 Y446 N448 D21 V57 R58 S59 G60 G61 H62 C63 V68 L79 A98 G120 F121 C122 V125 G126 G128 G129 H130 G135 Y136 G189 G190 G193 I195 Y444 N446 TRAAVTVKPDDHRYDLLARADNYRFVAQPEYFRLPYSTAQVVEAVSEAVAAGKRLTVRSGGHCGEAFVASPDVDVIVDLSSMSHVGYDEERGAFEVEAGATVGQIYRVLYKNYGVTFPGGFCMGVGAGGHISGGGYGPLSRLLGLTVDYLHAVEVVVVDAEGVVSTVVATREEDDPNRDLWWAHTGGGGGNFGVITRYWLRSPDAVGDAPEEALPRPPASFHVARVSWSWAELTEADYVRLVSNFLDWQLRNCTVDSPNIGLYALLECFHRSAGHLAMHAQIPVDVPDAEERMSWFLAELNEGVAVAPSLTRRRLPWLATSQLLAIPDVGPGAIGVRRKVKSADLRGPHTREQLAAAYRHLSRADYHCPSAAMEYIAYGGRVNTVDPAATAVPRGASLKTFYMVAWTDPDEDEEHLRWIREIYRDIHSATGGVPTPDEVNTGAYINYPDIDLADPEWNTSGVPWHTIYYGDNYPRLQEIKSRWDPRNVFRHAFSIRPR 5i1w B 2.15 BS02 67L B 1 H64 G66 F123 F403 M405 Y449 H62 G64 F121 F401 M403 Y447 TRAAVTVKPDDHRYDLLARADNYRFVAQPEYFRLPYSTAQVVEAVSEAVAAGKRLTVRSGGHCGEAFVASPDVDVIVDLSSMSHVGYDEERGAFEVEAGATVGQIYRVLYKNYGVTFPGGFCMGVGAGGHISGGGYGPLSRLLGLTVDYLHAVEVVVVDAEGVVSTVVATREEDDPNRDLWWAHTGGGGGNFGVITRYWLRSPDAVGDAPEEALPRPPASFHVARVSWSWAELTEADYVRLVSNFLDWQLRNCTVDSPNIGLYALLECFHRSAGHLAMHAQIPVDVPDAEERMSWFLAELNEGVAVAPSLTRRRLPWLATSQLLAIPDVGPGAIGVRRKVKSADLRGPHTREQLAAAYRHLSRADYHCPSAAMEYIAYGGRVNTVDPAATAVPRGASLKTFYMVAWTDPDEDEEHLRWIREIYRDIHSATGGVPTPDEVNTGAYINYPDIDLADPEWNTSGVPWHTIYYGDNYPRLQEIKSRWDPRNVFRHAFSIRPR 5i1w C 2.15 BS02 67L C 1 H64 G66 F123 C124 F403 M405 Y449 H62 G64 F121 C122 F401 M403 Y447 TRAAVTVKPDDHRYDLLARADNYRFVAQPEYFRLPYSTAQVVEAVSEAVAAGKRLTVRSGGHCGEAFVASPDVDVIVDLSSMSHVGYDEERGAFEVEAGATVGQIYRVLYKNYGVTFPGGFCMGVGAGGHISGGGYGPLSRLLGLTVDYLHAVEVVVVDAEGVVSTVVATREEDDPNRDLWWAHTGGGGGNFGVITRYWLRSPDAVGDAPEEALPRPPASFHVARVSWSWAELTEADYVRLVSNFLDWQLRNCTVDSPNIGLYALLECFHRSAGHLAMHAQIPVDVPDAEERMSWFLAELNEGVAVAPSLTRRRLPWLATSQLLAIPDVGPGAIGVRRKVKSADLRGPHTREQLAAAYRHLSRADYHCPSAAMEYIAYGGRVNTVDPAATAVPRGASLKTFYMVAWTDPDEDEEHLRWIREIYRDIHSATGGVPTPDEVNTGAYINYPDIDLADPEWNTSGVPWHTIYYGDNYPRLQEIKSRWDPRNVFRHAFSIRPR 5i1w D 2.15 BS02 67K D 1 H64 G66 F123 C124 I328 F403 M405 Y449 H62 G64 F121 C122 I326 F401 M403 Y447 TRAAVTVKPDDHRYDLLARADNYRFVAQPEYFRLPYSTAQVVEAVSEAVAAGKRLTVRSGGHCGEAFVASPDVDVIVDLSSMSHVGYDEERGAFEVEAGATVGQIYRVLYKNYGVTFPGGFCMGVGAGGHISGGGYGPLSRLLGLTVDYLHAVEVVVVDAEGVVSTVVATREEDDPNRDLWWAHTGGGGGNFGVITRYWLRSPDAVGDAPEEALPRPPASFHVARVSWSWAELTEADYVRLVSNFLDWQLRNCTVDSPNIGLYALLECFHRSAGHLAMHAQIPVDVPDAEERMSWFLAELNEGVAVAPSLTRRRLPWLATSQLLAIPDVGPGAIGVRRKVKSADLRGPHTREQLAAAYRHLSRADYHCPSAAMEYIAYGGRVNTVDPAATAVPRGASLKTFYMVAWTDPDEDEEHLRWIREIYRDIHSATGGVPTPDEVNTGAYINYPDIDLADPEWNTSGVPWHTIYYGDNYPRLQEIKSRWDPRNVFRHAFSIRPR 5i4x A 1.61 BS01 URE A 1 A10 R14 L129 A10 R14 L129 3.2.1.17 27573790 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 5i4y A 1.61 BS04 URE A 4 G67 R68 T69 P70 S72 G67 R68 T69 P70 S72 3.2.1.17 27573790 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 5i4y A 1.61 BS06 URE A 6 E35 D52 Q57 A107 W108 V109 E35 D52 Q57 A107 W108 V109 3.2.1.17 27573790 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 5i4y A 1.61 BS07 URE A 7 C30 R114 T118 D119 W123 C30 R114 T118 D119 W123 3.2.1.17 27573790 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 5i4y A 1.61 BS08 URE A 8 N27 T118 V120 N27 T118 V120 3.2.1.17 27573790 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 5i4y A 1.61 BS09 URE A 9 G16 D18 N19 Y20 G16 D18 N19 Y20 3.2.1.17 27573790 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 5i51 A 1.54 BS01 TPP A 1 A30 H66 G114 P115 L116 D155 G156 E160 N185 I187 I189 H261 A29 H65 G113 P114 L115 D154 G155 E159 N184 I186 I188 H260 2.2.1.1 SSVDQKAISTIRLLAVDAVAAANSGHPGAPLGLAPAAHAVFKKMRFNPKDTKWINRDRFVLSNGHACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLGQGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGNLIAFWDDNKISIDGSTEVAFTEDVIARYKSYGWHIVEVSDADTDITAIAAAIDEAKKVTNKPTLVRLTTTIGFGSLAQGTHGVHGAPLKADDIKQLKTKWGFNPEESFAVPAEVTASYNEHVAENQKIQQQWNELFAAYKQKYPELGAELQRRLDGKLPENWDKALPVYTPADAAVATLKLSEIVLSKIIPEVPEIIGGSADLTPSNLTKAKGTVDFQPAATGLGDYSGRYIRYGVREHAMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGAVRLSALSEFPITWVATHDSIGLGEDGPTHQPIETLAHFRATPNISVWRPADGNETSAAYKSAIESTHTPHILALTRQNLPQLEGSSIEKASKGGYTLVQQDKADIIIVATGSEVSLAVDALKVLEGQGIKAGVVSLPDQLTFDKQSEEYKLSVLPDGVPILSVEVMSTFGWSKYSHQQFGLNRFGASGKAPEIFKLFEFTPEGVAERAAKTVAFYKGKDVVSPLRSAF 5i51 A 1.54 BS02 F6R A 1 H27 H66 H100 I189 H261 H26 H65 H99 I188 H260 2.2.1.1 SSVDQKAISTIRLLAVDAVAAANSGHPGAPLGLAPAAHAVFKKMRFNPKDTKWINRDRFVLSNGHACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLGQGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGNLIAFWDDNKISIDGSTEVAFTEDVIARYKSYGWHIVEVSDADTDITAIAAAIDEAKKVTNKPTLVRLTTTIGFGSLAQGTHGVHGAPLKADDIKQLKTKWGFNPEESFAVPAEVTASYNEHVAENQKIQQQWNELFAAYKQKYPELGAELQRRLDGKLPENWDKALPVYTPADAAVATLKLSEIVLSKIIPEVPEIIGGSADLTPSNLTKAKGTVDFQPAATGLGDYSGRYIRYGVREHAMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGAVRLSALSEFPITWVATHDSIGLGEDGPTHQPIETLAHFRATPNISVWRPADGNETSAAYKSAIESTHTPHILALTRQNLPQLEGSSIEKASKGGYTLVQQDKADIIIVATGSEVSLAVDALKVLEGQGIKAGVVSLPDQLTFDKQSEEYKLSVLPDGVPILSVEVMSTFGWSKYSHQQFGLNRFGASGKAPEIFKLFEFTPEGVAERAAKTVAFYKGKDVVSPLRSAF 5i53 A 1.61 BS06 URE A 6 E35 Q57 A107 W108 V109 E35 Q57 A107 W108 V109 3.2.1.17 27573790 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 5i5e A 1.62 BS01 TPP A 1 A30 C66 G114 P115 L116 D155 G156 E160 N185 I187 S188 I189 I248 C261 A29 C65 G113 P114 L115 D154 G155 E159 N184 I186 S187 I188 I247 C260 2.2.1.1 SSVDQKAISTIRLLAVDAVAAANSGHPGAPLGLAPAAHAVFKKMRFNPKDTKWINRDRFVLSNGCACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLGQGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGNLIAFWDDNKISIDGSTEVAFTEDVIARYKSYGWHIVEVSDADTDITAIAAAIDEAKKVTNKPTLVRLTTTIGFGSLAQGTHGVCGAPLKADDIKQLKTKWGFNPEESFAVPAEVTASYNEHVAENQKIQQQWNELFAAYKQKYPELGAELQRRLDGKLPENWDKALPVYTPADAAVATRKLSEIVLSKIIPEVPEIIGGSADLTPSNLTKAKGTVDFQPAATGLGDYSGRYIRYGVREHAMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGAVRLSALSEFPITWVATHDSIGLGEDGPTHQPIETLAHFRATPNISVWRPADGNETSAAYKSAIESTHTPHILALTRQNLPQLEGSSIEKASKGGYTLVQQDKADIIIVATGSEVSLAVDALKVLEGQGIKAGVVSLPDQLTFDKQSEEYKLSVLPDGVPILSVEVMSTFGWSKYSHQQFGLNRFGASGKAPEIFKLFEFTPEGVAERAAKTVAFYKGKDVVSPLRSAF 5i5e A 1.62 BS02 5SP A 1 H27 H100 I189 H26 H99 I188 2.2.1.1 SSVDQKAISTIRLLAVDAVAAANSGHPGAPLGLAPAAHAVFKKMRFNPKDTKWINRDRFVLSNGCACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLGQGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGNLIAFWDDNKISIDGSTEVAFTEDVIARYKSYGWHIVEVSDADTDITAIAAAIDEAKKVTNKPTLVRLTTTIGFGSLAQGTHGVCGAPLKADDIKQLKTKWGFNPEESFAVPAEVTASYNEHVAENQKIQQQWNELFAAYKQKYPELGAELQRRLDGKLPENWDKALPVYTPADAAVATRKLSEIVLSKIIPEVPEIIGGSADLTPSNLTKAKGTVDFQPAATGLGDYSGRYIRYGVREHAMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGAVRLSALSEFPITWVATHDSIGLGEDGPTHQPIETLAHFRATPNISVWRPADGNETSAAYKSAIESTHTPHILALTRQNLPQLEGSSIEKASKGGYTLVQQDKADIIIVATGSEVSLAVDALKVLEGQGIKAGVVSLPDQLTFDKQSEEYKLSVLPDGVPILSVEVMSTFGWSKYSHQQFGLNRFGASGKAPEIFKLFEFTPEGVAERAAKTVAFYKGKDVVSPLRSAF 5i5g A 1.95 BS01 POP A 1 A30 H66 G154 D155 G156 N185 I187 I248 H261 A29 H65 G153 D154 G155 N184 I186 I247 H260 2.2.1.1 SSVDQKAISTIRLLAVDAVAAANSGHPGAPLGLAPAAHAVFKKMRFNPKDTKWINRDRFVLSNGHACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLGQGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGNLIAFWDDNKISIDGSTEVAFTEDVIARYKSYGWHIVEVSDADTDITAIAAAIDEAKKVTNKPTLVRLTTTIGFGSLAQGTHGVHGAPLKADDIKQLKTKWGFNPEESFAVPAEVTASYNEHVAENQKIQQQWNELFAAYKQKYPELGAELQRRLDGKLPENWDKALPVYTPADAAVATRKLSEIVLSKIIPEVPEIIGGSADLTPSNLTKAKGTVDFQPAATGLGDYSGRYIRYGVREHAMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGAVRLSALSEFPITWVATHDSIGLGEDGPTHQPIETLAHFRATPNISVWRPADGNETSAAYKSAIESTHTPHILALTLQNLPQLEGSSIEKASKGGYTLVQQDKADIIIVATGSEVSLAVDALKVLEGQGIKAGVVSLPDQLTFDKQSEEYKLSVLPDGVPILSVEVMSTFGWSKYSHQQFGLNRFGASGKAPEIFKLFEFTPEGVAERAAKTVAFYKGKDVVSPLRSAF 5ims A 1.98 BS01 FAD A 1 R241 G307 A308 G309 N312 T334 L335 L352 G353 M354 H355 G356 G374 A375 R376 D378 R380 V381 E407 V408 N412 G425 D426 A427 R159 G218 A219 G220 N223 T245 L246 L263 G264 M265 H266 G267 G285 A286 R287 D289 R291 V292 E318 V319 N323 G336 D337 A338 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDK 5ims A 1.98 BS04 OXY A 1 G116 A117 T162 S163 Q202 G34 A35 T80 S81 Q120 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDK 5ims A 1.98 BS05 OXY A 2 A551 Q600 A462 Q494 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDK 5ims A 1.98 BS06 TPP B 1 Y113 P114 G115 E139 T162 P165 N169 Y31 P32 G33 E57 T80 P83 N87 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDK 5ims B 1.98 BS02 OXY A 3 Y113 K137 Y31 K55 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 5ims B 1.98 BS03 FAD B 1 R241 G307 A308 G309 N312 T334 L335 Q336 L352 M354 H355 G374 A375 R376 D378 R380 V381 E407 V408 N412 G425 D426 A427 Q501 M502 G520 R159 G225 A226 G227 N230 T252 L253 Q254 L270 M272 H273 G292 A293 R294 D296 R298 V299 E325 V326 N330 G343 D344 A345 Q419 M420 G438 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 5ims B 1.98 BS07 OXY B 2 E578 Q580 H599 Q600 E496 Q498 H517 Q518 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 5ims B 1.98 BS08 OXY B 3 E578 Q600 L601 N602 E496 Q518 L519 N520 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 5inu A 1.98 BS04 PYR A 1 G115 G116 F201 Q202 G33 G34 F119 Q120 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEESHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKK 5inu A 1.98 BS05 PYR A 2 G116 A117 S163 F201 Q202 K251 G34 A35 S81 F119 Q120 K169 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEESHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKK 5inu A 1.98 BS07 OXY A 2 G115 G116 A117 T162 S163 Q202 G33 G34 A35 T80 S81 Q120 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEESHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKK 5inu B 1.98 BS07 PYR B 2 G116 S163 G34 S81 2.2.1.6 PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVD 5inv B 2.28 BS08 OXY B 3 E578 L601 N602 E486 L505 N506 2.2.1.6 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQIEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 5inv B 2.28 BS09 FAD B 1 R241 G307 A308 G309 N312 T334 L335 L352 M354 H355 G374 A375 R376 D378 R380 V381 E407 V408 G425 D426 A427 M502 G520 G521 R158 G220 A221 G222 N225 T247 L248 L265 M267 H268 G287 A288 R289 D291 R293 V294 E320 V321 G338 D339 A340 M410 G428 G429 2.2.1.6 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQIEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 5j7s A 2.37 BS01 6H3 A 1 V42 G43 V50 A61 M104 E105 Y106 A107 G110 L163 C174 F176 V16 G17 V22 A33 M65 E66 Y67 A68 G71 L124 C135 F137 2.7.11.25 28011204 SLHMIDYKEIEVEEVVGRGGVVCKAKWRAKDVAIKKAFIVELRQLSRVNHPNIVKLYLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQHSLPPGEDGRVEPYVDFAEFYRLWSVDHG 5j8i A 2.40 BS01 6H4 A 1 V42 V50 A61 M104 E105 Y106 A107 L163 C174 D175 V16 V22 A33 M75 E76 Y77 A78 L134 C145 D146 2.7.11.25 28011204 SLHMIDYKEIEVEEVVGRFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGCLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQHSLPPGEDGRVEPYVDFAEFYRLWSVDHG 5j9l A 2.75 BS01 6HF A 1 V42 V50 A61 V90 M104 E105 Y106 A107 G110 S111 Y113 N114 P160 L163 F176 V16 V22 A31 V60 M72 E73 Y74 A75 G78 S79 Y81 N82 P128 L131 F144 2.7.11.25 28011204 SLHMIDYKEIEVEEVVGRGGVVCKAWRADVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYCLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQHSLPPGEDGRVEPYVDFAEFYRLWSVDHG 5jgn A 1.53 BS01 V1A A 1 R8 C9 L164 R8 C9 L164 3.2.1.17 MNIFEMLRCDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKNL 5jgr A 1.46 BS01 V1A A 1 L39 N40 C43 N55 G56 L39 N40 C43 N55 G56 3.2.1.17 MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAACSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKNL 5jgu A 1.47 BS01 V1A A 1 C119 Q122 Q123 C119 Q122 Q123 3.2.1.17 MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLCMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKNL 5jgv A 1.73 BS01 V1A A 1 C73 R76 R80 C73 R76 R80 3.2.1.17 MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDCAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKN 5jgz A 1.53 BS01 V1A A 1 C151 R154 T155 D159 C151 R154 T155 D159 3.2.1.17 MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVICTFRTGTWDAYKN 5jh6 A 2.37 BS01 T92 A 1 V42 V50 A61 M104 E105 Y106 A107 L163 C174 F176 V16 V23 A34 M74 E75 Y76 A77 L133 C144 F146 2.7.11.25 28011204 SLHMIDYKEIEVEEVVGRGAFVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQHSLPPGEDGRVEPYVDFAEFYRLWSVDHG 5jk3 A 2.37 BS01 6L4 A 1 V42 E105 Y106 A107 G110 P160 L163 C174 V12 E57 Y58 A59 G62 P112 L115 C126 2.7.11.25 28011204 SLHMIIEVEEVVGRVCKAIKQISESERKAFIVELRQLSRVNHPNIVKLYNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQHSLPPGEDGRVEPYVDFAEFYRLWSVDHG 5jw7 B 2.85 BS01 ZN B 1 C21 C24 C41 C44 C4 C7 C24 C27 6.3.2.- 28084320 FLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNFF 5jw7 B 2.85 BS02 ZN B 2 C36 H38 C56 C59 C19 H21 C39 C42 6.3.2.- 28084320 FLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNFF 5kgr A 1.47 BS01 V1A A 1 C9 L164 C9 L164 3.2.1.17 MNIFEMLRCDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAACNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKNL 5kia A 2.10 BS01 ZN A 1 C93 C96 C99 C107 C91 C94 C97 C105 1.1.1.103 HMKALAKLEPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVMHVGHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNREGAFAEYLAIPAFNAFKIPPEISDDLAAIFDPFGNATHTALSFNLVGEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMTEGFDVGLEMSGVPSAFTSLLESMNHGGKVALLGIPPAQTAIDWNQVIFKGLEIKGIYGREMFETWYKMVAMLQSGLDLSPIITHRFAVDDYEKGFAAMLSGESGKVILDWA 5kia A 2.10 BS02 CA A 1 D148 N152 E290 D146 N150 E288 1.1.1.103 HMKALAKLEPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVMHVGHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNREGAFAEYLAIPAFNAFKIPPEISDDLAAIFDPFGNATHTALSFNLVGEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMTEGFDVGLEMSGVPSAFTSLLESMNHGGKVALLGIPPAQTAIDWNQVIFKGLEIKGIYGREMFETWYKMVAMLQSGLDLSPIITHRFAVDDYEKGFAAMLSGESGKVILDWA 5kkh A 2.13 BS01 RET A 1 Y91 W94 T97 T98 L101 M126 G130 W146 S149 T150 M153 W190 Y193 P194 W197 A223 K224 Y81 W84 T87 T88 L91 M116 G120 W136 S139 T140 M143 W180 Y183 P184 W187 A213 K214 LGVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYADWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 5kkh B 2.13 BS01 RET B 1 Y91 W94 T98 M126 W146 S149 T150 M153 W190 Y193 P194 W197 D220 A223 K224 Y81 W84 T88 M116 W136 S139 T140 M143 W180 Y183 P184 W187 D210 A213 K214 LGVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYADWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 5kkk A 1.70 BS01 HEM A 1 T40 K43 F44 R46 H65 T68 V69 A72 L90 S93 H94 H98 I100 Y104 L105 T40 K43 F44 R46 H65 T68 V69 A72 L90 S93 H94 H98 I100 Y104 L105 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG 5ko7 A 2.25 BS01 FMN A 1 R34 R35 T36 R38 L170 T171 H172 T173 L194 L210 R212 R30 R31 T32 R34 L148 T149 H150 T151 L172 L188 R190 PAFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYHH 5ko7 A 2.25 BS02 FMN B 1 P61 S62 G63 H65 Y146 E149 S150 I153 P57 S58 G59 H61 Y124 E127 S128 I131 PAFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYHH 5ko7 B 2.25 BS01 FMN A 1 P61 S62 G63 H65 Y146 E149 S150 I153 P57 S58 G59 H61 Y122 E125 S126 I129 PAFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYHH 5ko7 B 2.25 BS02 FMN B 1 R34 R35 T36 R38 L170 T171 H172 T173 L194 L210 R212 R30 R31 T32 R34 L146 T147 H148 T149 L170 L186 R188 PAFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYHH 5ko8 A 2.15 BS01 FMN A 1 R34 R35 T36 R38 F110 T112 L170 T171 H172 T173 L194 L210 R212 R29 R30 T31 R33 F102 T104 L162 T163 H164 T165 L186 L202 R204 AFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESYNGNEWLEDLQPFGTDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYH 5ko8 A 2.15 BS02 IYR A 1 E91 Y95 W103 L107 T112 K116 H172 E86 Y90 W95 L99 T104 K108 H164 AFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESYNGNEWLEDLQPFGTDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYH 5ko8 B 2.15 BS01 FMN B 1 R34 R35 T36 R38 F110 L170 T171 T173 L194 L210 R212 R29 R30 T31 R33 F105 L165 T166 T168 L189 L205 R207 AFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESYNGRMSNEWLEDLQPFGTDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYH 5ko8 B 2.15 BS02 IYR B 1 E91 Y95 L107 T112 K116 E86 Y90 L102 T107 K111 AFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESYNGRMSNEWLEDLQPFGTDWHKPFLEIAPYLIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTPSPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYH 5kr9 A 2.25 BS02 CUE A 1 M343 L346 L349 A350 E353 L387 M388 L391 R394 M421 L428 H524 L525 M40 L43 L46 A47 E50 L84 M85 L88 R91 M118 L125 H211 L212 28042045 NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL 5kr9 B 2.25 BS02 CUE B 1 M343 L346 E353 L387 M388 L391 R394 M421 L428 H524 L525 M39 L42 E49 L83 M84 L87 R90 M117 L124 H209 L210 28042045 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5kra A 2.40 BS02 6WS A 1 L346 A350 E353 L387 R394 F404 M421 I424 F425 L428 L525 L37 A41 E44 L78 R85 F95 M109 I112 F113 L116 L203 28042045 SLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5kra B 2.40 BS02 6WT B 1 M343 L346 T347 A350 E353 M388 R394 F404 M421 I424 F425 L428 L525 M39 L42 T43 A46 E49 M84 R90 F100 M114 I117 F118 L121 L216 28042045 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL 5krc A 2.40 BS02 ZER A 1 L346 T347 L349 A350 E353 L387 M388 L391 M421 I424 L428 G521 M528 L41 T42 L44 A45 E48 L82 M83 L86 M116 I119 L123 G206 M213 28042045 NSLALSLTADQMVSALLDAEPPILYSEYDRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5krf A 2.19 BS02 6WL A 1 M343 L346 E353 L387 M388 L391 R394 F404 M421 G521 H524 M40 L43 E50 L84 M85 L88 R91 F101 M118 G207 H210 28042045 NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5krf B 2.19 BS02 6WL B 1 L349 A350 E353 L387 M388 L391 R394 M421 G521 L45 A46 E49 L83 M84 L87 R90 M113 G208 28042045 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL 5krh A 2.24 BS02 6WN A 1 M343 A350 E353 L387 L391 R394 F404 G420 M421 I424 G521 H524 L525 M37 A44 E47 L81 L85 R88 F98 G114 M115 I118 G204 H207 L208 28042045 SLALSLTADQMVSALLDAEPPILYSEYDRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5krh B 2.24 BS02 6WN B 1 M343 E353 L387 M388 R394 F404 G420 I424 M517 K520 G521 H524 L525 M39 E49 L83 M84 R90 F100 G114 I118 M206 K209 G210 H213 L214 28042045 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5lca A 1.93 BS03 B06 A 1 F62 Y67 W87 H116 D118 H179 Y201 G209 N210 D213 H240 F24 Y29 W49 H78 D80 H141 Y163 G171 N172 D175 H202 IPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHT 5lcf A 1.86 BS03 6TJ A 1 F62 Y67 W87 H116 D118 H179 G209 N210 H240 F24 Y29 W49 H78 D80 H141 G171 N172 H202 IPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHT 5lch A 1.94 BS03 6TU A 1 F62 Y67 W87 H116 D118 H179 R205 G209 N210 H240 F30 Y35 W55 H84 D86 H147 R173 G177 N178 H208 YPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 5le1 A 1.40 BS03 6UW A 1 F62 Y67 W87 H116 D117 D118 H179 G209 N210 H240 F31 Y36 W56 H85 D86 D87 H148 G178 N179 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5le1 A 1.40 BS04 FMT A 1 S138 R141 L142 S107 R110 L111 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 5lgx A 1.50 BS01 FMN A 1 A23 P24 L25 T26 A58 Q100 H181 H184 R233 L275 G301 A302 F322 G323 R324 F350 Y351 A22 P23 L24 T25 A57 Q99 H180 H183 R232 L274 G300 A301 F321 G322 R323 F349 Y350 AEKLFTPLKVGAVTAPNRVFMAPLTRLRSIEPGDIPTPLMGEYYRQRASAGLIISEATQISAQAKGYAGAPGLHSPEQIAAWKKITAGVHAEDGRIAVQLWHTGRISHSSIQPGGQAPVSASALNANTRTSLRDENGNAIRVDTTTPRALELDEIPGIVNDFRQAVANAREAGFDLVELHSAHGYLLHQFLSPSSNQRTDQYGGSVENRARLVLEVVDAVCNEWSADRIGIRVSPIGTFQNVDNGPNEEADALYLIEELAKRGIAYLHMSETDLAGGKPYSEAFRQKVRERFHGVIIGAGAYTAEKAEDLIGKGLIDAVAFGRDYIANPDLVARLQKKAELNPQRPESFYGGGAEGYTDYPSL 5lm6 A 1.17 BS03 H32 A 1 Y67 W87 H116 D117 D118 H179 G209 N210 H240 Y36 W56 H85 D86 D87 H148 G178 N179 H209 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNR 5lsw A 2.15 BS01 III B 1 H85 N88 Q98 R130 P131 E133 Y134 L137 T138 G141 G144 K148 L177 T180 V181 F184 R227 H231 H73 N76 Q86 R118 P119 E121 Y122 L125 T126 G129 G132 K136 L165 T168 V169 F172 R215 H219 28165457 GPHMLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5lsw A 2.15 BS02 III D 1 R274 W275 Q278 R262 W263 Q266 28165457 GPHMLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5lsw C 2.15 BS01 III B 1 R274 Q278 R262 Q266 28165457 GPHMLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5lsw C 2.15 BS02 III D 1 R46 H85 N88 Q98 R130 Y134 L137 T138 G141 G144 K148 F184 R227 H231 R34 H73 N76 Q86 R118 Y122 L125 T126 G129 G132 K136 F172 R215 H219 28165457 GPHMLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQE 5lu3 A 1.50 BS01 2NV A 1 W54 E86 W54 E86 GEYLEMDLPFSYDGAGEYLWKTDDFSTTVDWGRYVNSWNLDLLEINGNDYTNRWVAQHQVPPASDGYWYIHYKGSLAWSHVEMKLEHH 5lu3 A 1.50 BS02 CA A 1 D7 D23 D24 D7 D23 D24 GEYLEMDLPFSYDGAGEYLWKTDDFSTTVDWGRYVNSWNLDLLEINGNDYTNRWVAQHQVPPASDGYWYIHYKGSLAWSHVEMKLEHH 5m2f X 1.50 BS02 UV8 X 1 W21 Y49 W80 H111 W112 F123 P124 R125 G129 A131 L301 L302 W21 Y49 W80 H111 W112 F123 P124 R125 G129 A131 L301 L302 1.1.1.- 28161411 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPRDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNLLQSSHLEDYPFNAEY 5m58 A 2.05 BS01 SAH A 1 E4 P5 I6 F14 Y25 C47 C48 G49 D70 L71 S72 M75 G95 D96 A97 R116 H117 A118 L122 E4 P5 I6 F14 Y25 C47 C48 G49 D70 L71 S72 M75 G95 D96 A97 R116 H117 A118 L122 2.1.1.- 28152088 MKIEPITGSEAEAFHRMGSRAFERYNEFVDLLVGAGIADGQTVVDLCCGSGELEIILTSRFPSLNLVGVDLSEDMVRIARDYAAEQGKELEFRHGDAQSPAGMEDLLGKADLVVSRHAFHRLTRLPAGFDTMLRLVKPGGAILNVSFLHLSDFDEPGFRTWVRFLKERPWDAEMQVAWALAHYYAPRLQDYRDALAQAADETPVSEQRIWVDDQGYGVATVKCFARRAAA 5msm A 2.29 BS01 III C 1 K16 S41 D43 K44 D45 K46 S47 E48 V49 K61 Q62 R63 K64 H65 S66 N67 R111 K15 S37 D39 K40 D41 K42 S43 E44 V45 K57 Q58 R59 K60 H61 S62 N63 R107 SINLHSAPEYDPSYKLIQLTPELLDIIQDPHQLRFKSLDKDKSEVVLCSHDKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGFAKTESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENSPCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQHLNVEDTHHAVGKDIEDEFNPYTREIIETVLNKFAVQENTWRLRIPFIAQWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEELNSRGMKIDSFIMKYARRKRLGKKTVVTSR 5msm B 2.29 BS01 III C 1 P2 V4 Q36 G37 E38 E40 L41 P42 R51 R58 I68 V84 G85 K86 K87 Q88 F106 N107 S108 N111 K112 K126 D127 R128 P129 P1 V3 Q35 G36 E37 E39 L40 P41 R50 R57 I67 V83 G84 K85 K86 Q87 F105 N106 S107 N110 K111 K125 D126 R127 P128 PSVDIDASQWQKLTQSREKQTTVITPLGMMMLEIQGELELPKDFASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKKQRLLGKVTKLDVPMGIMHFNSKDNKVELVDVMKYKVIFKDRPLPIM 5msm D 2.29 BS01 III F 1 K16 S41 D43 K44 D45 S47 E48 V49 L60 K61 Q62 R63 K64 H65 S66 N67 F108 K15 S37 D39 K40 D41 S43 E44 V45 L56 K57 Q58 R59 K60 H61 S62 N63 F104 SINLHSAPEYDPSYKLIQLTPELLDIIQDPHQLRFKSLDKDKSEVVLCSHDKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGFAKTESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENSPCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQHLNVEDTHHAVGKDIEDEFNPYTREIIETVLNKFAVQEQNTWRLRIPFIAQWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEESRGMKIDSFIMKYARRKRLGKKTVVTSR 5msm E 2.29 BS01 III F 1 P2 S3 V4 Q36 G37 E38 E40 R58 I68 R69 F70 V84 G85 Q88 F106 N107 S108 N111 K112 K126 D127 R128 P129 P1 S2 V3 Q28 G29 E30 E32 R50 I60 R61 F62 V76 G77 Q80 F98 N99 S100 N103 K104 K118 D119 R120 P121 PSVDIDASQWQKLTTVITPLGMMMLEIQGELELPKDFASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKKQRLLGKVTKLDVPMGIMHFNSKDNKVELVDVMKYKVIFKDRPLPI 5mt0 A 1.29 BS01 QJS A 1 H40 L41 C42 H57 W141 G142 I143 R151 K192 G193 S195 S215 H24 L25 C26 H41 W128 G129 I130 R137 K180 G181 S183 S199 3.4.21.46 28157311 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLASA 5mt4 A 1.65 BS01 M7O A 1 H40 L41 H57 C58 W141 G142 I143 R151 K192 G193 S195 S215 H24 L25 H41 C42 W128 G129 I130 R137 K180 G181 S183 S199 3.4.21.46 28157311 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 5mtp A 2.00 BS02 53K A 1 G96 F97 M103 F149 M155 P156 A157 Y158 M161 A198 M199 I202 V203 Q214 L217 L218 G95 F96 M102 F148 M154 P155 A156 Y157 M160 A197 M198 I201 V202 Q213 L216 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5mtp B 2.00 BS02 53K B 1 G96 F97 M103 F149 M155 P156 Y158 M161 A198 M199 I202 Q214 L217 L218 G95 F96 M102 F148 M154 P155 Y157 M160 A197 M198 I201 Q213 L216 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5mtp C 2.00 BS02 53K C 1 G96 F97 M98 M103 F149 M155 P156 A157 Y158 A198 M199 V203 Q214 L217 L218 G95 F96 M97 M102 F148 M154 P155 A156 Y157 A197 M198 V202 Q213 L216 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5mtq A 2.60 BS02 XT3 A 1 G96 F97 M103 F149 M155 Y158 M161 A198 M199 I202 V203 L218 G95 F96 M102 F148 M154 Y157 M160 A197 M198 I201 V202 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5mtq E 2.60 BS02 XT3 E 1 G96 F97 M103 F149 M155 Y158 M161 A198 M199 V203 Q214 L217 L218 G95 F96 M102 F148 M154 Y157 M160 A197 M198 V202 Q213 L216 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5mtr B 2.00 BS02 XT0 B 1 G96 F97 M103 F149 M155 P156 A157 Y158 M161 K165 A198 M199 I202 Q214 L218 G95 F96 M102 F148 M154 P155 A156 Y157 M160 K164 A197 M198 I201 Q213 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5mtr C 2.00 BS02 XT0 C 1 G96 F97 M103 F149 M155 P156 A157 Y158 M161 A198 M199 I202 V203 Q214 G95 F96 M102 F148 M154 P155 A156 Y157 M160 A197 M198 I201 V202 Q213 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5mtr F 2.00 BS02 XT0 F 1 G96 F97 M98 M103 F149 M155 P156 Y158 M161 A198 M199 I202 V203 Q214 L217 L218 G95 F96 M97 M102 F148 M154 P155 Y157 M160 A197 M198 I201 V202 Q213 L216 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5n1y A 1.39 BS01 III C 1 M5 Y7 M45 E63 K66 H70 T73 D77 Y84 Y99 Y116 T143 W147 A150 V152 L156 Y159 T163 W167 Y171 M6 Y8 M46 E64 K67 H71 T74 D78 Y85 Y100 Y117 T144 W148 A151 V153 L157 Y160 T164 W168 Y172 27183389 MGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP 5sw8 A 3.30 BS01 70S A 1 E620 K656 E602 K638 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRETSTKSLWVINSALRIKILCATYVNVIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNWNEWLNYDIYIPDLPRAARLCLSICSVCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTT 5sw8 A 3.30 BS02 FB1 A 1 D84 T86 E707 D98 T100 E689 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRETSTKSLWVINSALRIKILCATYVNVIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNWNEWLNYDIYIPDLPRAARLCLSICSVCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTT 5swg A 3.11 BS01 AX7 A 1 R818 C838 R808 C828 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSTSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWT 5swo A 3.50 BS01 70T A 1 K271 F666 C838 K287 F665 C837 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPTSMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWT 5swo B 3.50 BS01 2ZV B 1 N344 N377 N378 N15 N46 N47 28129991 SLQDAEWYWGREEVNEKLRDTADGTFLVRDTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWL 5swp A 3.41 BS01 70W A 1 D84 R87 R115 F119 R704 E707 D107 R110 R138 F142 R710 E713 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPTTFQGAMGSMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTK 5swp A 3.41 BS02 70V A 1 D725 E726 D731 E732 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPTTFQGAMGSMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTK 5swr A 3.31 BS01 718 A 1 Q296 Q760 Q316 Q761 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPQGAMGSMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWT 5swt A 3.49 BS01 71B A 1 R704 E707 R710 E713 2.7.1.153,2.7.11.1 28129991 MSYYHHHHHHDYDIPTTFQGAMGSMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTK 5sx8 A 3.47 BS01 LUZ A 1 S464 Q682 S466 Q681 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPTFQGAMGPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTK 5sx9 A 3.52 BS01 71L A 1 E542 N605 E539 N602 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPTQGAMGSMPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGAFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTT 5sxa A 3.35 BS01 71N A 1 Y265 D625 Y281 D622 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPTTLYQGPRSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWI 5sxd B 3.50 BS01 71F B 1 N377 N378 N44 N45 28129991 SLQDAEWYREEVNEKLRDTADGTFLVRDTKMHGDYTLTLRKGGNNKLIKIFHGKYLTFSSVVELINHYRNESLAQYNPVKLLYPVQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKKLNEWL 5sxj A 3.42 BS01 BHO A 1 R502 D578 R502 D574 2.7.1.153,2.7.11.1 28129991 SYYHHHHHHDYDIPTTQGAMPRSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLLQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGW 5t0x A BS01 III B 1 E11 F12 E14 A15 L18 F19 I27 V35 M36 L39 P43 M51 I52 E54 V55 I63 F68 M71 M72 K75 E11 F12 E14 A15 L18 F19 I27 V35 M36 L39 P43 M51 I52 E54 V55 I63 F68 M71 M72 K75 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 5t0x A BS02 III C 1 E84 I85 E87 A88 F92 I100 L105 V108 M109 L112 E114 L116 E120 E123 M124 I125 R126 E127 A128 V136 F141 M144 M145 T146 E84 I85 E87 A88 F92 I100 L105 V108 M109 L112 E114 L116 E120 E123 M124 I125 R126 E127 A128 V136 F141 M144 M145 T146 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 5t2u A 2.20 BS01 NAP A 1 G12 T14 S15 G16 I17 G36 R37 D38 R41 A58 D59 L60 N82 A83 Y86 T105 I132 T133 T134 Y147 K151 P177 G178 P179 T180 T182 T184 T185 G13 T15 S16 G17 I18 G37 R38 D39 R42 A59 D60 L61 N83 A84 Y87 T106 I133 T134 T135 Y148 K152 P178 G179 P180 T181 T183 T185 T186 28126742 HMELEGLTALVTGGTSGIGLESARLMAAEGADVVITGRDAQRGEQAAADIGHGARFVQADLGDLDSVADLAAQAPDVDILVNNAGIYPQASTFDQDVAGFQQLFDTNVRGTYFLVAAAAKGMVARGHGSIVNITTLAAHKGFPGTSVYGATKAALESLTRTWAAEFGANGVRVNSVSPGPTRTPTTLEQLGDFIDDVAAGLPLRRTAAPEEIAQAVLFLASPRASFVTGSTLYVDGGGYAV 5t2u C 2.20 BS01 NAP C 1 G12 T14 S15 G16 I17 R37 D38 R41 A58 D59 L60 N82 G84 Y86 T105 I132 T133 T134 Y147 K151 P177 G178 T180 T182 T184 T185 G13 T15 S16 G17 I18 R38 D39 R42 A59 D60 L61 N83 G85 Y87 T106 I133 T134 T135 Y148 K152 P178 G179 T181 T183 T185 T186 28126742 HMELEGLTALVTGGTSGIGLESARLMAAEGADVVITGRDAQRGEQAAADIGHGARFVQADLGDLDSVADLAAQAPDVDILVNNAGIYPQASTFDQDVAGFQQLFDTNVRGTYFLVAAAAKGMVARGHGSIVNITTLAAHKGFPGTSVYGATKAALESLTRTWAAEFGANGVRVNSVSPGPTRTPTTLEQLGDFIDDVAAGLPLRRTAAPEEIAQAVLFLASPRASFVTGSTLYVDGGGYAV 5t66 A 1.95 BS01 C6S A 1 C72 S73 K76 N107 Y108 S133 N135 N173 T238 G239 S240 C42 S43 K46 N77 Y78 S103 N105 N143 T208 G209 S210 3.5.2.6 28115348 ADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESRRDVLASAAKIVTDGL 5t6q A 2.70 BS01 HEM A 1 K105 Y110 L121 W129 R133 F140 F307 E310 G311 T314 P374 V375 V378 P440 F441 S442 R446 N447 C448 I449 G450 F453 A454 M458 K86 Y91 L102 W110 R114 F121 F278 E281 G282 T285 P345 V346 V349 P411 F412 S413 R417 N418 C419 I420 G421 F424 A425 M429 1.14.14.1 GFLKLLRLLLRRQRLARAMDSFPGPPTHWLFGHALEIQKTGSLDKVVTWTQQFPYAHPLWVGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFADSTRIMLEKWEKKACEGKSFDIFSDVGHMALDTLMKCTFGKGHRDSSYYVAVSELTLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACRAAHDHTDRVIRQRKAALQDEKEREKHLDFLDILLDVRGESGVQLSDTDLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQRCREEVREILGDQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFVDGRSLPAGSLISLHIYALHRNSDVWPDPEVFDPLRFSPENSSGRHPYAFIPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSVDPLRLPIKLPQLVLRSKNGIHLYLKPLG 5t6q A 2.70 BS02 OCT A 1 E310 T314 Q377 E281 T285 Q348 1.14.14.1 GFLKLLRLLLRRQRLARAMDSFPGPPTHWLFGHALEIQKTGSLDKVVTWTQQFPYAHPLWVGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGKGLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFADSTRIMLEKWEKKACEGKSFDIFSDVGHMALDTLMKCTFGKGHRDSSYYVAVSELTLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACRAAHDHTDRVIRQRKAALQDEKEREKHLDFLDILLDVRGESGVQLSDTDLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQRCREEVREILGDQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFVDGRSLPAGSLISLHIYALHRNSDVWPDPEVFDPLRFSPENSSGRHPYAFIPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSVDPLRLPIKLPQLVLRSKNGIHLYLKPLG 5t79 A 1.86 BS01 NDP A 1 G31 W33 N35 D61 Y66 K97 H138 S168 N169 Q193 F221 S222 L224 A225 G226 G227 T230 R232 S278 L295 I296 G297 A298 S299 Q303 D306 G31 W33 N35 D61 Y66 K97 H138 S168 N169 Q193 F221 S222 L224 A225 G226 G227 T230 R232 S263 L280 I281 G282 A283 S284 Q288 D291 28130301 MIYQPDENRYHTMEYRRCGRSGVKLPAISLGLWHNFGDTTRVENSRALLQRAFDLGITHFDLANNYGPPPGSAECNFGRILQEDFLPWRDELIISTKAGYTMWDGPYGDWGSRKYLIASLDQSLKRMGLEYVDIFYHHRPDPETPLKETMKALDHLVRHGKALYVGISNYPADLARQAIDILEDLGTPCLIHQPKYSLFERWVEDGLLALLQEKGVGSIAFSPLAGGQLTDRYLLKPEQITADKLEKVRRLNELAARRGQKLSQMALAWVLRNDNVTSVLIGASKPSQIEDAVGMLANRRFSAAECAEIDAILEG 5tbd E 2.20 BS01 III I 1 K30 D31 D32 Y33 H35 R50 D52 A54 G99 G100 K30 D31 D32 Y33 H35 R50 D52 A54 G99 G100 QVRLQQSGAELVKPGASVKLSCTASGFNIKDDYMHWVKQRPEQGLEWIGRIDPANGNTQYAPKFQDKATITADTSSNTAYLQLTSLTSEDTAVYYCARGGLLRWGQGTSVTVS 5tbd F 2.20 BS01 III I 1 H31 Y37 N39 R51 Y54 W94 G96 F99 H31 Y37 N39 R51 Y54 W94 G96 F99 DVVMTQTPLTLSVTIGQPASISCKSSQSLLHSNGKTYLNWLLQRPGQSPKRLIYLVSKLDSGVPDRFTGSGSGTDFTLKISSVEAEDLGVYYCWQGTHFPITFGSGTKLEI 5tbd B 2.20 BS01 III C 1 H31 Y37 N39 R51 Y54 L55 W94 G96 F99 H31 Y37 N39 R51 Y54 L55 W94 G96 F99 DVVMTQTPLTLSVTIGQPASISCKSSQSLLHSNGKTYLNWLLQRPGQSPKRLIYLVSKLDSGVPDRFTGSGSGTDFTLKISSVEAEDLGVYYCWQGTHFPITFGSGTKLE 5tbd D 2.20 BS01 III H 1 K30 D31 D32 Y33 H35 R50 D52 G99 G100 K30 D31 D32 Y33 H35 R50 D52 G99 G100 QVRLQQSGAELVKPGASVKLSCTASGFNIKDDYMHWVKQRPEQGLEWIGRIDPANGNTQYAPKFQDKATITADTSSNTAYLQLTSLTSEDTAVYYCARGGLLRWGQGTSVTVS 5tbd G 2.20 BS01 III H 1 H31 Y37 N39 R51 Y54 L55 W94 G96 H31 Y37 N39 R51 Y54 L55 W94 G96 DVVMTQTPLTLSVTIGQPASISCKSSQSLLHSNGKTYLNWLLQRPGQSPKRLIYLVSKLDSGVPDRFTGSGSGTDFTLKISSVEAEDLGVYYCWQGTHFPITFGSGTKLEIK 5tn9 A 2.25 BS01 7EC A 1 L346 A350 D351 E353 W383 L387 M388 R394 F404 I424 G521 N532 V533 P535 L41 A45 D46 E48 W78 L82 M83 R89 F99 I112 G203 N208 V209 P211 28032978 LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHKNVVPSYDLLLEMLDA 5tn9 B 2.25 BS01 7EC B 1 L346 T347 A350 D351 E353 L354 M388 R394 F404 I424 G521 L525 V533 P535 L539 L32 T33 A36 D37 E39 L40 M74 R80 F90 I105 G191 L195 V198 P200 L204 28032978 SLALSLTADQMVSALLDAEPPILYSESMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSVVPSYDLLLEMLDA 5tn9 C 2.25 BS01 7EC C 1 L346 A350 D351 E353 W383 L387 R394 F404 I424 G521 L525 V533 V534 P535 L40 A44 D45 E47 W77 L81 R88 F98 I111 G204 L208 V211 V212 P213 28032978 ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSVVPSYDLLLEMLDA 5tn9 D 2.25 BS01 7EC D 1 L346 T347 A350 D351 E353 L354 L387 M388 R394 F404 I424 G521 L525 P535 L539 L34 T35 A38 D39 E41 L42 L75 M76 R82 F92 I107 G201 L205 P208 L212 28032978 SLALSLTADQMVSALLDAEPPILYSEYDSMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYVPSYDLLLEMLDA 5tnb A 2.08 BS01 7EB A 1 L346 T347 A350 D351 E353 L387 R394 F404 M421 I424 F425 L428 G521 V534 P535 L41 T42 A45 D46 E48 L82 R89 F99 M108 I111 F112 L115 G206 V215 P216 28032978 LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKVPSYDLLLEMLDA 5tnb B 2.08 BS01 7EB B 1 T347 A350 D351 E353 L387 R394 M421 I424 F425 L428 G521 V534 P535 T39 A42 D43 E45 L79 R86 M109 I112 F113 L116 G195 V203 P204 28032978 SLALSLTADQMVSALLDAEPPILYSEYDPTRPSMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMVPSYDLLLEMLDA 5tnb C 2.08 BS01 7EB C 1 M342 M343 L346 T347 A350 D351 E353 W383 L387 L391 R394 F404 M421 I424 F425 L428 G521 L525 V533 P535 M37 M38 L41 T42 A45 D46 E48 W78 L82 L86 R89 F99 M110 I113 F114 L117 G208 L212 V216 P218 28032978 LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMVVPSYDLLLEMLDA 5tnb D 2.08 BS01 7EB D 1 M342 L346 T347 A350 D351 E353 R394 F404 M421 I424 F425 G521 V534 P535 M33 L37 T38 A41 D42 E44 R85 F95 M109 I112 F113 G208 V215 P216 28032978 SLALSLTADQMVSALLDAEPPILYSEYDPTRSMMGLLTNLADRELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSVPSYDLLLEMLDA 5tqc A 3.00 BS01 III B 1 K377 A380 D384 L419 A423 W460 E498 T506 E509 D543 K327 A330 D334 L369 A373 W410 E448 T456 E459 D493 28148929 EWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPTRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 5u16 A 2.00 BS01 7WO A 1 Y7 T34 K43 H58 Y62 W156 Y8 T35 K44 H59 Y63 W157 MRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHSGVHMVLQV 5u3j H 2.74 BS01 III A 1 T28 S30 N31 W33 R52A K52C D53 G97 P99 V100 V100A F100D F100E W100G G100H Y100J T28 S30 N31 W33 R53 K55 D56 G103 P105 V106 V107 F110 F111 W113 G114 Y116 EVQLVESGGGLVKPGGSLRLSCAASGFTFSNTWMSWVRQAPGKGLEWVGRISRNKDGAKTEYAAPVRGRFTISRDDSRDTLYLQMTSLKIEDSGRYFCTADLGEPVVSRFFEWGSYYYYMDLWGKGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS 5u3k H 2.64 BS01 III P 1 F28 D30 N31 W33 R52 R52A L52B K52C D53 E96 G97 P99 V100 F100C L100D W100F G100G Y100H F100I F28 D30 N31 W33 R52 R53 L54 K55 D56 E102 G103 P105 V106 F109 L110 W112 G113 Y114 F115 QVQLVQSGGGLVKPGGSLTLSCSASGFFFDNSWMGWVRQAPGKGLEWVGRIRRLKDGATGEYGAAVKDRFTISRDDSRNMLYLHMRTLKTEDSGTYYCTMDEGTPVTRFLEWGYFYYYMAVWGRGTTVIVSSASTKGPSVFPLAPSAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTPSSSLGTQTYICNVNHKPSNTKVDKRVE 5u3k H 2.64 BS02 CA H 1 D30 D73 N76 D30 D76 N79 QVQLVQSGGGLVKPGGSLTLSCSASGFFFDNSWMGWVRQAPGKGLEWVGRIRRLKDGATGEYGAAVKDRFTISRDDSRNMLYLHMRTLKTEDSGTYYCTMDEGTPVTRFLEWGYFYYYMAVWGRGTTVIVSSASTKGPSVFPLAPSAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTPSSSLGTQTYICNVNHKPSNTKVDKRVE 5u3k A 2.64 BS01 III C 1 F28 D30 N31 S32 W33 R52A K52C D53 E96 G97 P99 V100 F100C L100D W100F G100G Y100H F100I F28 D30 N31 S32 W33 R53 K55 D56 E102 G103 P105 V106 F109 L110 W112 G113 Y114 F115 QVQLVQSGGGLVKPGGSLTLSCSASGFFFDNSWMGWVRQAPGKGLEWVGRIRRLKDGATGEYGAAVKDRFTISRDDSRNMLYLHMRTLKTEDSGTYYCTMDEGTPVTRFLEWGYFYYYMAVWGRGTTVIVSSASTKGPSVFPLAGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSYICNVNHKPSNTKVDKRVEP 5u3l H 2.17 BS01 III P 1 F28 D30 N31 W33 R52 R52A K52C D53 E96 G97 P99 V100 F100C W100F G100G Y100H F100I Y100K F28 D30 N31 W33 R52 R53 K55 D56 E102 G103 P105 V106 F109 W112 G113 Y114 F115 Y117 QVQLVQSGGGLVKPGGSLTLSCSASGFFFDNSWMGWVRQAPGKGLEWVGRIRRLKDGATGEYGAAVKDRFTISRDDSRNMLYLHMRTLKTEDSGTYYCTMDEGTPVTRFLEWGYFYYYMAVWGRGTTVIVSSASTKGPSVFPLAPSSSTSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSYICNVNHKPSNTKVDKRVEP 5u3l A 2.17 BS01 III C 1 N31 S32 W33 R52 R52A K52C D53 E96 G97 P99 V100 F100C L100D W100F G100G Y100H F100I N31 S32 W33 R52 R53 K55 D56 E102 G103 P105 V106 F109 L110 W112 G113 Y114 F115 QVQLVQSGGGLVKPGGSLTLSCSASGFFFDNSWMGWVRQAPGKGLEWVGRIRRLKDGATGEYGAAVKDRFTISRDDSRNMLYLHMRTLKTEDSGTYYCTMDEGTPVTRFLEWGYFYYYMAVWGRGTTVIVSSASTKGPSVFPLAGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTTYICNVNHKPSNTKVDKRVEP 5u3m H 2.42 BS01 III A 1 T28 S30 N31 W33 R52A D53 I56 E96 G97 P99 I100 L100A F100C F100D E100E W100F G100G Y100H Y100I T28 S30 N31 W33 R53 D56 I59 E102 G103 P105 I106 L107 F109 F110 E111 W112 G113 Y114 Y115 QVQLVQSGGGLVKPGGSLTLSCVTSGFTFSNTWMSWVRQTPGKGLEWVARISRVGDGPIIDYAAPVKGRFIISRDDSRNTLFLHMNNLKTEDTAVYYCTADEGAPILRFFEWGYYNYYMDVWGKGTTVIVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSC 5u3o H 1.76 BS01 III A 1 N31 W33 R52 R52A K52C D53 G97 P99 V100 F100C L100D W100F G100G Y100H F100I Y100K N31 W33 R52 R53 K55 D56 G103 P105 V106 F109 L110 W112 G113 Y114 F115 Y117 QVQLVQSGGGLVKPGGSLTLSCSASGFFFDNSWMGWVRQAPGKGLEWVGRIRRLKDGATGEYGAAVKDRFTISRDDSRNMLYLHMRTLKTEDSGTYYCTMDEGTPVTRFLEWGYFYYYMAVWGRGTTVIVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSC 5u8u A 1.35 BS01 FAD A 1 I10 G11 A12 G13 P14 G15 E34 K35 Y36 G47 T48 C49 V52 G53 C54 S57 K58 G120 H121 G122 A150 S151 G152 S153 S171 L175 I192 R279 G318 D319 M325 L326 A327 H328 Y358 I8 G9 A10 G11 P12 G13 E32 K33 Y34 G45 T46 C47 V50 G51 C52 S55 K56 G118 H119 G120 A148 S149 G150 S151 S169 L173 I190 R277 G316 D317 M323 L324 A325 H326 Y356 1.8.1.4 QKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHIAN 5u8v A 1.45 BS02 NAD A 1 I187 G188 G190 V191 I192 L210 E211 A212 L213 A243 V245 A276 V277 G278 I185 G186 G188 V189 I190 L208 E209 A210 L211 A241 V243 A274 V275 G276 1.8.1.4 QKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHIAN 5u8v C 1.45 BS02 NAD C 1 I187 G188 A189 G190 V191 I192 L210 E211 A212 L213 A276 V277 G278 I186 G187 A188 G189 V190 I191 L209 E210 A211 L212 A275 V276 G277 1.8.1.4 SQKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHIANR 5u8v D 1.45 BS03 NAD D 1 I187 G188 A189 G190 V191 I192 L210 E211 A212 L213 A243 R244 V245 A276 V277 G278 I188 G189 A190 G191 V192 I193 L211 E212 A213 L214 A244 R245 V246 A277 V278 G279 1.8.1.4 HMSQKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHIAN 5u8w A 1.79 BS01 FAD A 1 I10 G11 A12 G13 P14 G15 I33 E34 K35 Y36 G47 T48 C49 V52 G53 C54 S57 K58 G120 H121 G122 A150 S151 G152 S171 L175 I192 L196 R279 L286 G318 D319 M325 L326 A327 H328 Y358 I9 G10 A11 G12 P13 G14 I32 E33 K34 Y35 G46 T47 C48 V51 G52 C53 S56 K57 G119 H120 G121 A149 S150 G151 S170 L174 I191 L195 R278 L285 G317 D318 M324 L325 A326 H327 Y357 1.8.1.4 SQKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHIAN 5u8w A 1.79 BS02 NAI A 1 I187 G188 A189 G190 V191 I192 E195 L210 E211 A212 L213 A276 V277 G278 R279 M325 L326 V356 Y358 I186 G187 A188 G189 V190 I191 E194 L209 E210 A211 L212 A275 V276 G277 R278 M324 L325 V355 Y357 1.8.1.4 SQKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHIAN 5u8w C 1.79 BS02 NAI C 1 K58 I158 I187 G188 G190 V191 I192 E195 L210 E211 A212 L213 A276 V277 G278 R279 M325 L326 V356 Y358 K57 I157 I186 G187 G189 V190 I191 E194 L209 E210 A211 L212 A275 V276 G277 R278 M324 L325 V355 Y357 1.8.1.4 SQKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHIAN 5u8w D 1.79 BS03 NAI D 1 K58 I187 G188 G190 V191 I192 E195 L210 E211 A212 L213 A243 R244 V245 A276 V277 G278 R279 M325 L326 V356 Y358 K56 I185 G186 G188 V189 I190 E193 L208 E209 A210 L211 A241 R242 V243 A274 V275 G276 R277 M323 L324 V354 Y356 1.8.1.4 QKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHEAALAVNGHAIHIAN 5uc9 A 1.90 BS01 MYR A 1 F53 A70 L74 Y134 R156 L167 A226 N230 I233 F234 F23 A40 L44 Y104 R126 L137 A196 N200 I203 F204 1.14.14.18 28132836 ADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQ 5uc9 B 1.90 BS01 MYR B 1 E49 F53 A70 L74 R156 L167 N230 I233 F234 E20 F24 A41 L45 R127 L138 N201 I204 F205 1.14.14.18 28132836 MADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQA 5uc9 C 1.90 BS01 MYR C 1 F53 A70 L74 Y134 R156 A226 N230 I233 F234 F23 A40 L44 Y104 R126 A196 N200 I203 F204 1.14.14.18 28132836 ADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQA 5uc9 D 1.90 BS01 MYR D 1 F53 F57 A70 L74 T77 R156 L167 N230 I233 F234 F23 F27 A40 L44 T47 R126 L137 N200 I203 F204 1.14.14.18 28132836 ADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQA 5ue8 A 3.35 BS01 ZN A 1 C580 C583 H605 C608 C40 C43 H65 C68 28177287 NNEELKNHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDRTQNIIMVLKDRMKIRERNKPEIFELIQEVFAVTKSAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQAGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIKVRVWDESDDFLGQTIIEVRTLSGEMDVWYNLDKSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHFVTDVQNNGVVKIPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYANVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYGREYQPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWSLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVAELPTFKDRVPEYPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQLFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIVSKDFASYCSKEKEKVPCILMNNTQQLRVQLEKMFEAMGGKELDAEASGTLKELQVKLNNVLDELSHVFATSFQPHIEECVRQMGDILSQVKGVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMERTIKQCAVVELALDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQA 5ue8 A 3.35 BS02 ZN A 2 H567 C597 C600 C616 H27 C57 C60 C76 28177287 NNEELKNHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDRTQNIIMVLKDRMKIRERNKPEIFELIQEVFAVTKSAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQAGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIKVRVWDESDDFLGQTIIEVRTLSGEMDVWYNLDKSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHFVTDVQNNGVVKIPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYANVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYGREYQPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWSLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVAELPTFKDRVPEYPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQLFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIVSKDFASYCSKEKEKVPCILMNNTQQLRVQLEKMFEAMGGKELDAEASGTLKELQVKLNNVLDELSHVFATSFQPHIEECVRQMGDILSQVKGVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMERTIKQCAVVELALDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQA 5ufl A 3.00 BS01 ZN A 1 H334 C337 H299 C302 TACLKSLLLTVSQYKANATQLLRHLEVISRLFTSNQILTSECLSCLVELLEDPSASLILSIIGLLSQLAVDIETRDCLQNTLNSVLAGVVCRTDSVFLQCIQLLQKLTYNVKIFYSGANIDELITFLIDHIQSELKMPCLGLLANLCRHNLSVQTHIKTLSNSFYRTLITLLAHSSLTVVVFALSILSSLTLNEEVGEKLFHARNIHQTFQLIFNILINGDGTLTRKYSVDLLMDLLKNPKIADYLTRYEHFSSCLHQVLGLLNGKDPDSSSKVLELLLAFCSVTQLRHMLTQMMFESHTKCLEPTVALLRWLSQPLDGNCSVLALELFKEIFEDVIDAANCSSADRFVTLLLPTILDQLQFTEQNLDEALTRKKCERIAKAIEVLLTLCGDDTLKMHIAKILTTVKCTTLIEQQFTYGKIDLGFGTKVADSELCKLAADVILKTLDLINKLKPLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLRILLEAAPLPDFPALVLGESIAANNAYRQQE 5ugs A 2.80 BS02 XT5 A 1 G96 F97 M103 F149 M155 P156 A157 Y158 A198 M199 I202 Q214 L218 G95 F96 M102 F148 M154 P155 A156 Y157 A197 M198 I201 Q213 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5ugs A 2.80 BS03 XT5 A 2 T17 R43 L46 T196 L197 S200 T16 R42 L45 T195 L196 S199 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5ugs B 2.80 BS02 XT5 B 1 G96 F97 M98 M103 F149 A157 Y158 M161 A198 M199 V203 L218 G95 F96 M97 M102 F148 A156 Y157 M160 A197 M198 V202 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5ugs D 2.80 BS02 XT5 D 1 G96 F97 M103 F149 A157 Y158 A198 M199 I202 V203 Q214 L218 G95 F96 M102 F148 A156 Y157 A197 M198 I201 V202 Q213 L217 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5ugt A 2.60 BS02 XTW A 1 G96 F97 M98 M103 F149 A157 Y158 M161 A198 V203 L218 E219 G95 F96 M97 M102 F148 A156 Y157 M160 A197 V202 L217 E218 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5ugt B 2.60 BS02 XTW B 1 G96 F97 M103 F149 P156 A157 Y158 M161 A198 I202 L218 E219 G95 F96 M102 F148 P155 A156 Y157 M160 A197 I201 L210 E211 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5ugt E 2.60 BS02 XTW E 1 G96 F97 M103 F149 P156 A157 Y158 M161 A198 M199 V203 L218 E219 G95 F96 M102 F148 P155 A156 Y157 M160 A197 M198 V202 L217 E218 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5ugt G 2.60 BS02 XTW G 1 G96 F97 M103 F149 M155 P156 Y158 M161 A198 M199 I202 L218 E219 G95 F96 M102 F148 M154 P155 Y157 M160 A197 M198 I201 L213 E214 1.3.1.9 28151657 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5ul0 A 2.20 BS01 HEM A 1 F113 Y126 Y140 L147 K151 V311 G315 T318 H378 P379 L380 L383 R385 P462 F463 G464 H468 C470 G472 F475 A476 F107 Y120 Y134 L141 K145 V305 G309 T312 H372 P373 L374 L377 R379 P456 F457 G458 H462 C464 G466 F469 A470 IVGEALEYVNIGLSHFLALPLAQRISLIIIIPFIYNIVWQLLYSLRKDRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNNDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKIIWEKRNPEQKIGGRH 5ul0 A 2.20 BS02 VT1 A 1 Y72 Y126 L129 F134 I139 Y140 F236 P238 G310 G314 T318 L380 H381 S382 F384 M509 Y66 Y120 L123 F128 I133 Y134 F230 P232 G304 G308 T312 L374 H375 S376 F378 M503 IVGEALEYVNIGLSHFLALPLAQRISLIIIIPFIYNIVWQLLYSLRKDRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNNDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKIIWEKRNPEQKIGGRH 5umf A 1.40 BS01 ZN A 1 H34 D36 H67 D180 H32 D34 H65 D178 5.1.3.1 AYRIAPSILSADFARLGEEVANVIAAGADLIHFDVMDNHYVPNLTFGPMVCAALKPYASVPIDVHLMVEPVDDLIQSFAKAGASIITFHPEASRHIDRSLSLIRDMGCQAGLVLNPATPVYVLENVLDRLDMVLLMSVNPGFGGQSFIPHTLEKIRQVRAMLDRYEGKSGRRIAIEVDGGIKTDNIAAVARAGADTFVAGSAIFGKPDYKAVIAAMRAELEKA 5umf A 1.40 BS02 PO4 A 1 G145 G146 G182 A201 G202 S203 G143 G144 G180 A199 G200 S201 5.1.3.1 AYRIAPSILSADFARLGEEVANVIAAGADLIHFDVMDNHYVPNLTFGPMVCAALKPYASVPIDVHLMVEPVDDLIQSFAKAGASIITFHPEASRHIDRSLSLIRDMGCQAGLVLNPATPVYVLENVLDRLDMVLLMSVNPGFGGQSFIPHTLEKIRQVRAMLDRYEGKSGRRIAIEVDGGIKTDNIAAVARAGADTFVAGSAIFGKPDYKAVIAAMRAELEKA 5umf B 1.40 BS02 PO4 B 1 G146 G182 A201 G202 S203 G144 G180 A199 G200 S201 5.1.3.1 AYRIAPSILSADFARLGEEVANVIAAGADLIHFDVMDNHYVPNLTFGPMVCAALKPYASVPIDVHLMVEPVDDLIQSFAKAGASIITFHPEASRHIDRSLSLIRDMGCQAGLVLNPATPVYVLENVLDRLDMVLLMSVNPGFGGQSFIPHTLEKIRQVRAMLDRYEGKSGRRIAIEVDGGIKTDNIAAVARAGADTFVAGSAIFGKPDYKAVIAAMRAELEKA 5umh A 1.35 BS01 ZN A 1 Y164 H224 H226 Y162 H222 H224 1.13.11.1 VKVFDTKEVQDLLKAAANLNGDAGNARFRQIVHRLLSDLFKAIDDLDITPDEVWAGVNYLNKLGQDGEAALLAAGIGLEKYLDIRMDAADRAAGLDGGTPRTIEGPLYVAGAPVRDGVAKIDLDDDADAGPLVIRGTVTGTDGKPLAGALVECWHANSKGFYSHFDPTGAQTAFNLRGAVRTDANGKYEFRTLMPVGYGCPPQGATQQLLNGLGRHGNRPAHVHFFVSGDGHRKLTTQFNIEGDPLIWDDFAYATREELIPHVVDKTGGAALGMKSDAYKEIEFDIVLTPLLDGRDNQVVHRPRASA 5umh B 1.35 BS01 ZN B 1 Y164 Y200 H224 H226 Y163 Y199 H223 H225 1.13.11.1 SVKVFDTKEVQDLLKAAANLNGDAGNARFRQIVHRLLSDLFKAIDDLDITPDEVWAGVNYLNKLGQDGEAALLAAGIGLEKYLDIRMDAADRAAGLDGGTPRTIEGPLYVAGAPVRDGVAKIDLDDDADAGPLVIRGTVTGTDGKPLAGALVECWHANSKGFYSHFDPTGAQTAFNLRGAVRTDANGKYEFRTLMPVGYGCPPQGATQQLLNGLGRHGNRPAHVHFFVSGDGHRKLTTQFNIEGDPLIWDDFAYATREELIPHVVDKTGGAALGMKSDAYKEIEFDIVLTPLLDGRDNQVVHRPRASADA 5uof B 1.70 BS01 SER B 1 F107 P177 P178 F99 P169 P170 2.4.1.15 MSRLIVVSNRVAIGEDTRPSAGGLAVGVMDALQETGGVWFGWNGEIVGTPDAAPAIRRDGNVTYATVGLTRRDYDQYYRGFSNATLWPVFHYRGDLARFDRQEYAGYLRVNAMLAKQLAALLRPDDLIWVHDYHLLPFAHALRELGVKNPIGFFLHIPFPSPDVLRLVPPHDELVKFMCAYDVTGFQTDADRQAFTDYIERRGIGTASEDGMLHAHGRVVKVAAYPIGVYPDAIAQAAVQYGARKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAPPTDVQTYQRIRETLEGEAGRINGRFSQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELTGALLVNPYDLSQMADALERALSMPLAERQARHEENLARLRANDLSVWRDTFVADLRSVAAAAS 5wpz B 2.00 BS01 MAL B 1 N12 D14 K15 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 N12 D14 K15 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 28112203 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAARAAAEYKKILLLKGFELMDDYHFTSIKSLLAYDLGLTTKMQEEYNRIKITDLMEKKFQGVACLDKLIELAKDMPSLKNLVNNLRKEKSKVAKK 5wt9 G 2.40 BS01 FUC G 1 E61 F63 F82 Q99 E37 F39 F58 Q66 LDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPERFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAEL 5wv3 A 2.07 BS09 OSM A 7 R76 P149 N419 R76 P149 N419 1.11.1.7 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDSRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQKKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKMSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 5wv3 A 2.07 BS12 OSM A 10 V215 N216 Q217 E218 P228 V215 N216 Q217 E218 P228 1.11.1.7 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDSRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQKKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKMSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN