5b1s A 1.58 BS01 S4M A 1 Q40 L59 Q64 V65 Y73 H74 G95 D98 D118 I119 D120 V123 D149 G150 D168 T169 T170 P175 A176 L179 Y237 Q40 L59 Q64 V65 Y73 H74 G95 D98 D118 I119 D120 V123 D149 G150 D168 T169 T170 P175 A176 L179 Y237 2.5.1.16 Q4DA73 MPGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 5b1s A 1.58 BS02 BSX A 1 W19 Q64 Y73 T169 T170 D171 Q201 Y237 P238 I242 W19 Q64 Y73 T169 T170 D171 Q201 Y237 P238 I242 2.5.1.16 Q4DA73 MPGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 5b1s B 1.58 BS01 S4M B 1 Q40 M57 L59 Q64 Y73 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 T170 P175 A176 L179 Y237 Q40 M57 L59 Q64 Y73 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 T170 P175 A176 L179 Y237 2.5.1.16 Q4DA73 MPGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 5b6v A 2.00 BS01 RET A 1 Y83 W86 T90 L93 M118 G122 W138 S141 T142 M145 W182 Y185 P186 W189 D212 K216 Y80 W83 T87 L90 M115 G119 W135 S138 T139 M142 W179 Y182 P183 W186 D209 K213 P02945 ITGRPEWIWLALGTALMGLGTLYFLVKGMGVSDPDAKKFYAITTLVPAIAFTMYLSMLLGYGLTMVPFGGEQNPIYWARYADWLFTTPLLLLDLALLVDADQGTILALVGADGIMIGTGLVGALTKVYSYRFVWWAISTAAMLYILYVLFFGFTSKAESMRPEVASTFKVLRNVTVVLWSAYPVVWLIGSEGAGIVPLNIETLLFMVLDVSAKVGFGLILLRSRAIFGEAE 5b7n A 1.40 BS01 SAH A 1 A36 M37 V78 T104 A105 G106 E198 W199 E218 E219 M220 E221 R240 N244 A9 M10 V51 T77 A78 G79 E171 W172 E191 E192 M193 E194 R213 N217 3.2.2.16,3.2.2.9 A0KGU9 SAPILIQGAMDVEVETLVAALKDKQELTVGSWTYWQGTLSGYPVVVSRTEVGLANAAAATTLAMERFQPRLVINQGTAGGHDPALHRGDIVIGTKSFNMGAYRSDLTPAEQGVDPSKWHNFEVTMRLRDNGKLVEHSSFAGDPELVGRALGMADRYRHGRVVPGIIGTADEWNRQVARINWLHQTYQTAAEEMETSSAALVAEAYKVPFVGIRVLSNTDLHGEEFDPQTAIHCQQFVIDYAKALINGF 5b7n A 1.40 BS02 SAH B 1 F148 R153 F121 R126 3.2.2.16,3.2.2.9 A0KGU9 SAPILIQGAMDVEVETLVAALKDKQELTVGSWTYWQGTLSGYPVVVSRTEVGLANAAAATTLAMERFQPRLVINQGTAGGHDPALHRGDIVIGTKSFNMGAYRSDLTPAEQGVDPSKWHNFEVTMRLRDNGKLVEHSSFAGDPELVGRALGMADRYRHGRVVPGIIGTADEWNRQVARINWLHQTYQTAAEEMETSSAALVAEAYKVPFVGIRVLSNTDLHGEEFDPQTAIHCQQFVIDYAKALINGF 5bx1 A 1.90 BS01 4XA A 1 Y14 K15 N16 M124 F132 R159 Y7 K8 N9 M117 F125 R152 3.1.3.48 Q93096 APVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 5c3v A 3.15 BS01 ATP A 1 G154 A155 S156 S158 F160 I169 K171 N222 N223 L224 D236 T257 L303 I377 D378 G98 A99 S100 S102 F104 I113 K115 N166 N167 L168 D180 T201 L247 I275 D276 Q503I3 TTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILHMGGIPAFNSKGERLLVFIGIIDILQSYRTVSVHRPSFYADRFQKFMCSTVFRK 5c3v A 3.15 BS02 CA A 1 K238 D299 S301 D378 K182 D243 S245 D276 Q503I3 TTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILHMGGIPAFNSKGERLLVFIGIIDILQSYRTVSVHRPSFYADRFQKFMCSTVFRK 5eub A 1.81 BS02 5S7 A 1 A94 C95 G96 I172 F177 I194 N195 M196 T219 D220 D222 V233 V236 A85 C86 G87 I163 F168 I185 N186 M187 T210 D211 D213 V224 V227 2.4.2.28 Q13126 VKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKNMAQFSVLLP 5f5n A 1.30 BS01 NAD A 1 G12 T14 G15 T16 Q17 R37 D58 L59 V78 Q79 T80 F81 V114 K129 P148 T149 F151 N154 G8 T10 G11 T12 Q13 R33 D54 L55 V74 Q75 T76 F77 V110 K125 P144 T145 F147 N150 A0A023GUL3 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAGVSLVTGDLNDQASLRAAMADVHGVFSVQTFMTPGGLGAELRQGRAVADAAAATGVRHVVYSSVGGADRASGVPHFETKWTIERHLRSLGVPTTVLRPTFFMDNFAAWGPQAVDGTLVVRLPLKPQTRVQLIAAEDIGVFAATAFDDPDTYVGAALELAGDELTGPELAARFGELAGMPARFEERSLDEAAADPWIPYSHEIAVMFEWFQTDGYAADIAALRARHPGLRTFADWLRAIGWRVP 5f5n A 1.30 BS02 5VD A 1 F81 M82 H125 F150 N154 F155 W158 L171 I246 I252 M255 F259 Y264 F77 M78 H121 F146 N150 F151 W154 L167 I242 I248 M251 F255 Y260 A0A023GUL3 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAGVSLVTGDLNDQASLRAAMADVHGVFSVQTFMTPGGLGAELRQGRAVADAAAATGVRHVVYSSVGGADRASGVPHFETKWTIERHLRSLGVPTTVLRPTFFMDNFAAWGPQAVDGTLVVRLPLKPQTRVQLIAAEDIGVFAATAFDDPDTYVGAALELAGDELTGPELAARFGELAGMPARFEERSLDEAAADPWIPYSHEIAVMFEWFQTDGYAADIAALRARHPGLRTFADWLRAIGWRVP 5f5n B 1.30 BS01 NAD B 1 G12 T14 G15 T16 Q17 R37 D58 L59 Q79 F81 V114 K129 P148 T149 F151 N154 G8 T10 G11 T12 Q13 R33 D54 L55 Q75 F77 V110 K125 P144 T145 F147 N150 A0A023GUL3 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAGVSLVTGDLNDQASLRAAMADVHGVFSVQTFMTPGGLGAELRQGRAVADAAAATGVRHVVYSSVGGADRASGVPHFETKWTIERHLRSLGVPTTVLRPTFFMDNFAAWGPQAVDGTLVVRLPLKPQTRVQLIAAEDIGVFAATAFDDPDTYVGAALELAGDELTGPELAARFGELAGMPARFEERSLDEAAADPWIPYSHEIAVMFEWFQTDGYAADIAALRARHPGLRTFADWLRAIGWRVP 5f5n B 1.30 BS03 MG B 1 V32 S53 V28 S49 A0A023GUL3 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAGVSLVTGDLNDQASLRAAMADVHGVFSVQTFMTPGGLGAELRQGRAVADAAAATGVRHVVYSSVGGADRASGVPHFETKWTIERHLRSLGVPTTVLRPTFFMDNFAAWGPQAVDGTLVVRLPLKPQTRVQLIAAEDIGVFAATAFDDPDTYVGAALELAGDELTGPELAARFGELAGMPARFEERSLDEAAADPWIPYSHEIAVMFEWFQTDGYAADIAALRARHPGLRTFADWLRAIGWRVP 5f7d A 2.30 BS01 III C 1 M5 Y7 F9 M45 E63 R65 K66 V67 H70 T73 H74 D77 T80 L81 R97 Y99 Y116 K146 W147 V152 L156 Y159 W167 Y171 M4 Y6 F8 M44 E62 R64 K65 V66 H69 T72 H73 D76 T79 L80 R96 Y98 Y115 K145 W146 V151 L155 Y158 W166 Y170 P01892 SHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 5f9j A 2.51 BS01 III C 1 Y7 F9 M45 E63 K66 V67 H70 T73 D77 L81 Y99 Y123 T143 K146 W147 Q155 Y159 T163 W167 Y171 Y7 F9 M45 E63 K66 V67 H70 T73 D77 L81 Y99 Y123 T143 K146 W147 Q155 Y159 T163 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 5f9l A 2.59 BS01 NUC T 1 Q38 Y39 W42 G46 R61 S62 K86 R93 K293 K311 R313 P316 K317 T318 I319 G320 S322 K323 N324 P326 G327 T329 R351 Q41 Y42 W45 G49 R64 S65 K89 R96 K292 K310 R312 P315 K316 T317 I318 G319 S321 K322 N323 P325 G326 T328 R350 2.7.7.7 Q9Y253 GPHMATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSAS 5f9n A 2.23 BS01 NUC T 1 Q38 Y39 W42 R61 S62 W64 K86 R93 K293 K311 R313 P316 K317 T318 I319 G320 C321 S322 K323 N324 P326 G327 T329 R351 L378 Q41 Y42 W45 R64 S65 W67 K89 R96 K291 K309 R311 P314 K315 T316 I317 G318 C319 S320 K321 N322 P324 G325 T327 R349 L376 2.7.7.7 Q9Y253 GPHMATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSAS 5fa4 A 2.40 BS01 III C 1 M5 Y7 F9 M45 E63 K66 V67 H70 T73 D77 L81 Y84 Y99 Y116 Y123 T143 K146 W147 Q155 Y159 T163 W167 Y171 M4 Y6 F8 M44 E62 K65 V66 H69 T72 D76 L80 Y83 Y98 Y115 Y122 T142 K145 W146 Q154 Y158 T162 W166 Y170 P01892 SHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 5fac A 2.80 BS01 PLP A 1 K46 Y50 W96 W179 H181 S222 R237 P238 G239 I240 Y374 K39 Y43 W89 W172 H174 S215 R230 P231 G232 I233 Y367 5.1.1.1 O86786 RDADAVLRARAEIDLAALRANVRALRERAPGAALMAVVKADAYGHGAIPCARAAVAAGATWLGTATPQEALALRAAEPGLPDDVRIMCWLWTPGGPWREAVEARLDVSVSAMWAMEEVTGAARAAGVPARVQLKADTGLGRGGCQPGADWERLVGAALRAEEEGLLRVTGLWSHFACADEPGHPSIAAQLTRFREMTAYAEQRGLRPEVRHIANSPATLTLPDAHFDLVRPGIAMYGVSPSPEIGTPADFGLRPVMTLAASLALVKQVPGGHGVSYGHHYTTPGETTLGLVPLGYADGIPRHASSSGPVLVDGKWRTVAGRIAMDQFVVDLGGDRPEPGAEAVLFGPGDRGEPTAEDWAQAAGTIAYEIVTRIGSRVPRVYVNE 5fac B 2.80 BS01 PLP B 1 K46 Y50 W96 W179 N221 S222 R237 G239 I240 Y374 K36 Y40 W86 W169 N211 S212 R227 G229 I230 Y364 5.1.1.1 O86786 DAVLRARAEIDLAALRANVRALRERAPGAALMAVVKADAYGHGAIPCARAAVAAGATWLGTATPQEALALRAAEPGLPDDVRIMCWLWTPGGPWREAVEARLDVSVSAMWAMEEVTGAARAAGVPARVQLKADTGLGRGGCQPGADWERLVGAALRAEEEGLLRVTGLWSHFACADEPGHPSIAAQLTRFREMTAYAEQRGLRPEVRHIANSPATLTLPDAHFDLVRPGIAMYGVSPSPEIGTPADFGLRPVMTLAASLALVKQVPGGHGVSYGHHYTTPGETTLGLVPLGYADGIPRHASSSGPVLVDGKWRTVAGRIAMDQFVVDLGGDRPEPGAEAVLFGPGDRGEPTAEDWAQAAGTIAYEIVTRIGSRVPRVYVNE 5fag A 1.51 BS01 PLP A 1 K46 Y50 W96 K141 W179 H181 N221 S222 R237 P238 G239 I240 Y374 K45 Y49 W95 K140 W178 H180 N220 S221 R236 P237 G238 I239 Y373 5.1.1.1 O86786 SETTARRDADAVLRARAEIDLAALRANVRALRERAPGAALMAVVKADAYGHGAIPCARAAVAAGATWLGTATPQEALALRAAEPGLPDDVRIMCWLWTPGGPWREAVEARLDVSVSAMWAMEEVTGAARAAGVPARVQLKADTGLGRGGCQPGADWERLVGAALRAEEEGLLRVTGLWSHFACADEPGHPSIAAQLTRFREMTAYAEQRGLRPEVRHIANSPATLTLPDAHFDLVRPGIAMYGVSPSPEIGTPADFGLRPVMTLAASLALVKQVPGGHGVSYGHHYTTPGETTLGLVPLGYADGIPRHASSSGPVLVDGKWRTVAGRIAMDQFVVDLGGDRPEPGAEAVLFGPGDRGEPTAEDWAQAAGTIAYEIVTRIGSRVPRVYVNE 5faj A 1.64 BS02 DCS B 1 Y283 Y302 A330 M331 Y277 Y296 A324 M325 5.1.1.1 O86786 RRDADAVLRARAEIDLAALRANVRALRERAPGAALMAVVKADAYGHGAIPCARAAVAAGATWLGTATPQEALALRAAEPGLPDDVRIMCWLWTPGGPWREAVEARLDVSVSAMWAMEEVTGAARAAGVPARVQLKADTGLGRGGCQPGADWERLVGAALRAEEEGLLRVTGLWSHFACADEPGHPSIAAQLTRFREMTAYAEQRGLRPEVRHIANSPATLTLPDAHFDLVRPGIAMYGVSPSPEIGTPADFGLRPVMTLAASLALVKQVPGGHGVSYGHHYTTPGETTLGLVPLGYADGIPRHASSSGPVLVDGKWRTVAGRIAMDQFVVDLGGDRPEPGAEAVLFGPGDRGEPTAEDWAQAAGTIAYEIVTRIGSRVPRVYVNE 5faj D 1.64 BS02 DCS D 1 K46 Y50 W96 R148 W179 H181 N221 S222 P223 R237 P238 G239 I240 Y374 K37 Y41 W87 R139 W170 H172 N212 S213 P214 R228 P229 G230 I231 Y365 5.1.1.1 O86786 ADAVLRARAEIDLAALRANVRALRERAPGAALMAVVKADAYGHGAIPCARAAVAAGATWLGTATPQEALALRAAEPGLPDDVRIMCWLWTPGGPWREAVEARLDVSVSAMWAMEEVTGAARAAGVPARVQLKADTGLGRGGCQPGADWERLVGAALRAEEEGLLRVTGLWSHFACADEPGHPSIAAQLTRFREMTAYAEQRGLRPEVRHIANSPATLTLPDAHFDLVRPGIAMYGVSPSPEIGTPADFGLRPVMTLAASLALVKQVPGGHGVSYGHHYTTPGETTLGLVPLGYADGIPRHASSSGPVLVDGKWRTVAGRIAMDQFVVDLGGDRPEPGAEAVLFGPGDRGEPTAEDWAQAAGTIAYEIVTRIGSRVPRVYVNE 5fdw A 2.70 BS01 III C 1 Y7 F9 M45 E63 K66 V67 H70 T73 D77 T80 L81 Y84 R97 Y99 Y116 Y123 T143 K146 W147 V152 Q155 Y159 T163 W167 Y171 Y7 F9 M45 E63 K66 V67 H70 T73 D77 T80 L81 Y84 R97 Y99 Y116 Y123 T143 K146 W147 V152 Q155 Y159 T163 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 5fen A 1.55 BS01 RET A 1 F16 Y19 M20 T51 C53 Y60 V62 L77 K108 F16 Y19 M20 T51 C53 Y60 V62 L77 K108 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTLVIDQDGDNFKTKCTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 5fen B 1.55 BS01 RET B 1 F16 Y19 M20 T51 F57 Y60 V62 L77 W106 K108 F16 Y19 M20 T51 F57 Y60 V62 L77 W106 K108 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTLVIDQDGDNFKTKCTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 5ffh A 1.68 BS01 RET A 1 F16 W19 M20 A33 T53 W58 Y60 L77 W106 K108 L117 F16 W19 M20 A33 T53 W58 Y60 L77 W106 K108 L117 P50120 TRDQNGTWEMESNENFEGWMKALDIDFATRKIAVRLTQTLVIDQDGDNFKVKTTSTFWNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 5ffz A 2.59 BS01 ET A 1 N31 G34 H35 G38 F104 N32 G35 H36 G39 F105 Q5Y812 SNEFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 5fgl A 2.40 BS01 6HY A 1 R91 Y114 Q118 L138 Y154 V185 I188 R62 Y85 Q89 L105 Y121 V152 I155 A0A0B4KIF6 MELILNEAEKVFAMHGFLGATLKQIAQNSNVTQALITYYYGTKQNLFMEVYRRGLSDIDKKRQNYLDELKSRPEGYNTYDIVRTYLRPQFEHQAWMHFARLQSRLASEPEEVAVPLRKELYDHTLKAFIHEIMECEGEDDAAAVSWGAVFMVSMILYMLRGVDRIGELTDGHLHAESEDDIVERMTIFITGGINSLKQAT 5fgl A 2.40 BS02 6HY B 1 Y190 R193 R197 Y157 R160 R164 A0A0B4KIF6 MELILNEAEKVFAMHGFLGATLKQIAQNSNVTQALITYYYGTKQNLFMEVYRRGLSDIDKKRQNYLDELKSRPEGYNTYDIVRTYLRPQFEHQAWMHFARLQSRLASEPEEVAVPLRKELYDHTLKAFIHEIMECEGEDDAAAVSWGAVFMVSMILYMLRGVDRIGELTDGHLHAESEDDIVERMTIFITGGINSLKQAT 5fgl B 2.40 BS02 6HY B 1 R91 Y114 Q118 L138 R150 Y154 V185 I188 R62 Y85 Q89 L109 R121 Y125 V156 I159 A0A0B4KIF6 MELILNEAEKVFAMHGFLGATLKQIAQNSNVTQALITYYYGTKQNLFMEVYRRGLSDIDKKRQNYLDELKSRPEGYNTYDIVRTYLRPQFEHREAGQAWMHFARLQSRLASEPEEVAVPLRKELYDHTLKAFIHEIMECEGEDDAAAVSWGAVFMVSMILYMLRGVDRIGELTDGHLHAESEDDIVERMTIFITGGINSLKQATQD 5fgl C 2.40 BS01 6HY C 1 R91 Y114 Q118 L138 Y154 V185 I188 L189 R62 Y85 Q89 L106 Y122 V153 I156 L157 A0A0B4KIF6 MELILNEAEKVFAMHGFLGATLKQIAQNSNVTQALITYYYGTKQNLFMEVYRRGLSDIDKKRQNYLDELKSRPEGYNTYDIVRTYLRPQFEHRQAWMHFARLQSRLASEPEEVAVPLRKELYDHTLKAFIHEIMECEGEDDAAAVSWGAVFMVSMILYMLRGVDRIGELTDGHLHAESEDDIVERMTIFITGGINSLKQATQDKY 5fgl D 2.40 BS02 6HY D 1 R91 Y114 Q118 R150 Y154 V185 I188 R62 Y85 Q89 R118 Y122 V153 I156 A0A0B4KIF6 MELILNEAEKVFAMHGFLGATLKQIAQNSNVTQALITYYYGTKQNLFMEVYRRGLSDIDKKRQNYLDELKSRPEGYNTYDIVRTYLRPQFEHRQAWMHFARLQSRLASEPEEVAVPLRKELYDHTLKAFIHEIMECEGEDDAAAVSWGAVFMVSMILYMLRGVDRIGELTDGHLHAESEDDIVERMTIFITGGINSLKQATQD 5fgl E 2.40 BS01 6HY E 1 R91 Y114 Q118 Y154 V185 I188 R62 Y85 Q89 Y125 V156 I159 A0A0B4KIF6 MELILNEAEKVFAMHGFLGATLKQIAQNSNVTQALITYYYGTKQNLFMEVYRRGLSDIDKKRQNYLDELKSRPEGYNTYDIVRTYLRPQFEHREAGQAWMHFARLQSRLASEPEEVAVPLRKELYDHTLKAFIHEIMECEGEDDAAAVSWGAVFMVSMILYMLRGVDRIGELTDGHLHAESEDDIVERMTIFITGGINSLKQATQD 5fq6 A 2.80 BS01 III P 1 E54 N56 Q57 Q71 Y75 E54 N56 Q57 Q71 Y75 Q8A5H6 CDLNINDDPNYPMNDQVTADLIFPSISASIASAVGGEIYNYAGFFAQYYEQKPESNQYNTLCEYTFTESSQQMDYSYRILFAGALEDAKQVLEKTTNPADRFATTILRAYAFQIMVDNTSDSPYSEALQGNANATPKWDTGETVYKGILGEIDAAEAALDGSGMDVPDLIFNKNIAQWKGFANALRLRMYLRFIDANIDAASYTEKVKTLVQNNEFFTGDVKLDCFLDETDKRNPWYNTNAVGLTGNHCAAYPLVSYLSSTGDPRIAYGISKTDADGKYVGQLPGGKTHMQSILGTDNWKNKNVSAIDYSIGATKPVYFFTQAELQFLIAEVYARFHNDDANAKSAYEAGVTADFAVRGFAGQENTILEGACAWSAASTQADKLNLIYMQKWVSLFYMDHMEAWSEIRRTDCPKLSSYSAAQIQASESVYTPGELVAPWTNGLEAGGLMKRMTYPLSARQQNVNTPAGVPGSTPVWWDIK 5fq6 B 2.80 BS01 III P 1 L120 W202 E210 N211 Q326 Y363 F616 T743 G746 L747 N748 F839 L84 W166 E174 N175 Q290 Y327 F573 T700 G703 L704 N705 F796 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq6 B 2.80 BS02 KR0 B 1 Y402 M404 I457 Q459 G482 N483 E484 Y366 M368 I421 Q423 G446 N447 E448 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq6 B 2.80 BS03 CA B 1 D280 G281 I283 P284 T285 D288 D244 G245 I247 P248 T249 D252 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq6 C 2.80 BS01 III G 1 E54 N56 Q57 Y75 E54 N56 Q57 Y75 Q8A5H6 CDLNINDDPNYPMNDQVTADLIFPSISASIASAVGGEIYNYAGFFAQYYEQKPESNQYNTLCEYTFTESSQQMDYSYRILFAGALEDAKQVLEKTTNPADRFATTILRAYAFQIMVDNTSDSPYSEALQGNANATPKWDTGETVYKGILGEIDAAEAALDGSGMDVPDLIFNKNIAQWKGFANALRLRMYLRFIDANIDAASYTEKVKTLVQNNEFFTGDVKLDCFLDETDKRNPWYNTNAVGLTGNHCAAYPLVSYLSSTGDPRIAYGISKTDADGKYVGQLPGGKTHMQSILGTDNWKNKNVSAIDYSIGATKPVYFFTQAELQFLIAEVYARFHNDDANAKSAYEAGVTADFAVRGFAGQENTILEGACAWSAASTQADKLNLIYMQKWVSLFYMDHMEAWSEIRRTDCPKLSSYSAAQIQASESVYTPGELVAPWTNGLEAGGLMKRMTYPLSARQQNVNTPAGVPGSTPVWWDIK 5fq6 D 2.80 BS01 III G 1 L120 W202 E210 N211 Q326 F616 G746 L747 N748 F839 L84 W166 E174 N175 Q290 F577 G707 L708 N709 F800 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLLQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq6 D 2.80 BS02 KR0 D 1 Y402 M404 Q459 G482 N483 E484 Y366 M368 Q423 G446 N447 E448 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLLQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq6 H 2.80 BS01 III K 1 E54 S55 N56 Q57 E54 S55 N56 Q57 Q8A5H6 CDLNINDDPNYPMNDQVTADLIFPSISASIASAVGGEIYNYAGFFAQYYEQKPESNQYNTLCEYTFTESSQQMDYSYRILFAGALEDAKQVLEKTTNPADRFATTILRAYAFQIMVDNTSDSPYSEALQGNANATPKWDTGETVYKGILGEIDAAEAALDGSGMDVPDLIFNKNIAQWKGFANALRLRMYLRFIDANIDAASYTEKVKTLVQNNEFFTGDVKLDCFLDETDKRNPWYNTNAVGLTGNHCAAYPLVSYLSSTGDPRIAYGISKTDADGKYVGQLPGGKTHMQSILGTDNWKNKNVSAIDYSIGATKPVYFFTQAELQFLIAEVYARFHNDDANAKSAYEAGVTADFAVRGFAGQENTILEGACAWSAASTQADKLNLIYMQKWVSLFYMDHMEAWSEIRRTDCPKLSSYSAAQIQASESVYTPGELVAPWTNGLEAGGLMKRMTYPLSARQQNVNTPAGVPGSTPVWWDIK 5fq6 I 2.80 BS02 KR0 I 1 Y402 M404 I457 Q459 I461 G482 N483 E484 Y365 M367 I420 Q422 I424 G445 N446 E447 Q8A5H5 KALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLNDNLQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq6 M 2.80 BS01 III O 1 L120 E210 N211 Q326 Y363 F616 T743 G746 L747 N748 F839 L84 E174 N175 Q290 Y327 F580 T707 G710 L711 N712 F803 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLNDNLQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq6 M 2.80 BS02 KR0 M 1 Y402 I457 Q459 I461 G482 E484 M524 Y366 I421 Q423 I425 G446 E448 M488 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLNDNLQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq7 B 3.40 BS01 III P 1 W202 E210 N211 Q326 F616 G746 L747 N748 W166 E174 N175 Q290 F575 G705 L706 N707 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq7 B 3.40 BS02 MG B 1 S630 A631 N633 S589 A590 N592 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq7 C 3.40 BS02 MG D 1 A82 G83 A82 G83 Q8A5H6 CDLNINDDPNYPMNDQVTADLIFPSISASIASAVGGEIYNYAGFFAQYYEQKPESNQYNTLCEYTFTESSQQMDYSYRILFAGALEDAKQVLEKTTNPADRFATTILRAYAFQIMVDNTSDSPYSEALQGNANATPKWDTGETVYKGILGEIDAAEAALDGSGMDVPDLIFNKNIAQWKGFANALRLRMYLRFIDANIDAASYTEKVKTLVQNNEFFTGDVKLDCFLDETDKRNPWYNTNAVGLTGNHCAAYPLVSYLSSTGDPRIAYGISKTDADGKYVGQLPGGKTHMQSILGTDNWKNKNVSAIDYSIGATKPVYFFTQAELQFLIAEVYARFHNDDANAKSAYEAGVTADFAVRGFAGQENTILEGACAWSAASTQADKLNLIYMQKWVSLFYMDHMEAWSEIRRTDCPKLSSYSAAQIQASESVYTPGELVAPWTNGLEAGGLMKRMTYPLSARQQNVNTPAGVPGSTPVWWDIK 5fq7 D 3.40 BS01 III I 1 W202 E210 N211 Q326 Y363 F616 G746 L747 N748 F839 W165 E173 N174 Q289 Y326 F575 G705 L706 N707 F798 Q8A5H5 KALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq8 A 2.75 BS01 III P 1 E54 S55 N56 Q57 Q71 E54 S55 N56 Q57 Q71 Q8A5H6 CDLNINDDPNYPMNDQVTADLIFPSISASIASAVGGEIYNYAGFFAQYYEQKPESNQYNTLCEYTFTESSQQMDYSYRILFAGALEDAKQVLEKTTNPADRFATTILRAYAFQIMVDNTSDSPYSEALQGNANATPKWDTGETVYKGILGEIDAAEAALDGSGMDVPDLIFNKNIAQWKGFANALRLRMYLRFIDANIDAASYTEKVKTLVQNNEFFTGDVKLDCFLDETDKRNPWYNTNAVGLTGNHCAAYPLVSYLSSTGDPRIAYGISKTDADGKYVGQLPGGKTHMQSILGTDNWKNKNVSAIDYSIGATKPVYFFTQAELQFLIAEVYARFHNDDANAKSAYEAGVTADFAVRGFAGQENTILEGACAWSAASTQADKLNLIYMQKWVSLFYMDHMEAWSEIRRTDCPKLSSYSAAQIQASESVYTPGELVAPWTNGLEAGGLMKRMTYPLSARQQNVNTPAGVPGSTPVWWDIK 5fq8 B 2.75 BS02 KR0 B 1 Y402 M404 Q459 I461 G482 E484 Y366 M368 Q423 I425 G446 E448 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLLQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq8 B 2.75 BS03 MG B 1 A631 N633 A592 N594 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLLQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIVNGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq8 C 2.75 BS02 MG C 1 R408 D411 D478 I479 R408 D411 D478 I479 Q8A5H6 CDLNINDDPNYPMNDQVTADLIFPSISASIASAVGGEIYNYAGFFAQYYEQKPESNQYNTLCEYTFTESSQQMDYSYRILFAGALEDAKQVLEKTTNPADRFATTILRAYAFQIMVDNTSDSPYSEALQGNANATPKWDTGETVYKGILGEIDAAEAALDGSGMDVPDLIFNKNIAQWKGFANALRLRMYLRFIDANIDAASYTEKVKTLVQNNEFFTGDVKLDCFLDETDKRNPWYNTNAVGLTGNHCAAYPLVSYLSSTGDPRIAYGISKTDADGKYVGQLPGGKTHMQSILGTDNWKNKNVSAIDYSIGATKPVYFFTQAELQFLIAEVYARFHNDDANAKSAYEAGVTADFAVRGFAGQENTILEGACAWSAASTQADKLNLIYMQKWVSLFYMDHMEAWSEIRRTDCPKLSSYSAAQIQASESVYTPGELVAPWTNGLEAGGLMKRMTYPLSARQQNVNTPAGVPGSTPVWWDI 5fq8 D 2.75 BS02 KR0 D 1 Y402 I457 Q459 F480 G482 N483 E484 Y366 I421 Q423 F444 G446 N447 E448 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq8 D 2.75 BS05 CA D 2 E197 D850 E161 D809 Q8A5H5 EKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNEFGMGWNGNHTELENGSWGPRFDGSMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAGFRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINALVGFNGNERKVSYQYSEVNDLTIPTWFNLKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDWSSTLPKENRSFFYPGITGSFIFSELLDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGSLTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFSLAMDPASGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWSKVISLPEELGGITTIYGLNGGTSMYAITGMPVGVFKAQVAERDPQGRIVVNSSTGLPVEASEFGICGDMNNKYQMGVSTNLKYKGISLGIDFDIRQGGVMYSRTKDINYFTGNAIQTAYNDRNPLIVPNSVNKIGENVTYVENTTPITSSNIYKYWGDGGSDMGSCFLVDKSYVKLRSVVLGWDLPKRWLAKTPFQAVKVSAYGNNLFVWTPSSNTFIDPEMTSFGNDLEGNYGEYTANPSSRRFGFNLMVKF 5fq8 F 2.75 BS01 CA B 2 E13 K14 E11 K12 Q8A5H8 NDTEPGGTAVEKMAGDWWVTVNAFIDGKEVEDPFGAGHLQMSTYNTASNSETEMWLDDLGNFWEYKLKVNVNYAARTFSTTGFVDNVTYESKVKITDGKVLEKAATTPSGMPADSIVYMVQFDDDEDGLTYKVSGFRRTGFPADDF 5fqj A 2.27 BS01 6NT A 1 L225 D229 I250 P252 I259 V261 V286 F290 H291 L198 D202 I222 P224 I230 V232 V257 F261 H262 3.5.2.6 AQLSEQLAELEKRSGGRLGVAVLDTATGRRIAYRGDERFPMCSTFKALLAAAVLARVDQGKERLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITLSDNTAANLLLEALGGPAALTAFLRSIGDEVTRLDRWEPELNEAAPGDPRDTTTPAAMAATLRTLLLGDALSPASRQQLVDWLVANKTGDKRLRAGLPADDRVGDKTGTGGHGTTNDIAVIWPPGRAPIVVTVYLTESQVDADARDAVIAEVGRLVVEAFHHHH 5fqk A 1.77 BS01 6NT A 1 V48 P226 D229 I250 P252 I259 V261 V286 V287 W290 H291 V22 P199 D202 I222 P224 I230 V232 V257 V258 W261 H262 3.5.2.6 AALSEQLAELEKRSGGRLGVAVLDTATGRRFGYRGDERFPMCSTFKALLAAAVLARVDQGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITYSDNTAANLLLEALGGPAALTAFLRSIGDNVTRLDRWEPELNTAAPGDPRDTTTPAAMAATLRTLLLGDVLSPASRQQLVDWLIANKTGDKRLRAGLPADDRVGDKTGTGEHGTTNDIAVIWPPNRAPILVAVYLTESQVDADARDAVIAEVARLVVAAWHH 5gov B 2.33 BS03 ZN B 3 D106 D108 D83 D85 2.7.-.- A0A0R6L508 TIYHAKDAVQATKPMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSCGTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAITPTLLKLFDVTADKVKDRTAFI 5h1b A 4.40 BS01 NUC D 1 R235 R241 V270 A271 Q272 V273 K285 I287 G288 G289 N290 I291 R214 R220 V249 A250 Q251 V252 K257 I259 G260 G261 N262 I263 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1b A 4.40 BS02 ANP A 1 F129 R130 T131 G132 K133 T134 Q135 E163 R170 R310 I329 A331 F108 R109 T110 G111 K112 T113 Q114 E142 R149 R282 I301 A303 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1b A 4.40 BS03 MG A 1 K133 T134 K112 T113 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1b B 4.40 BS01 NUC D 1 R229 R235 L238 S239 R241 V270 A271 Q272 V273 K285 I287 G288 G289 N290 I291 R208 R214 L217 S218 R220 V249 A250 Q251 V252 K257 I259 G260 G261 N262 I263 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1b B 4.40 BS02 ANP A 1 A293 H294 D316 S317 P318 L320 P321 E322 A265 H266 D288 S289 P290 L292 P293 E294 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1b C 4.40 BS02 ANP B 1 A293 H294 S296 D316 S317 L320 P321 E322 A265 H266 S268 D288 S289 L292 P293 E294 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1c A 4.50 BS01 NUC D 1 R241 A271 Q272 I287 G288 G289 N290 I291 R220 A250 Q251 I262 G263 G264 N265 I266 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAADPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1c A 4.50 BS02 MG A 1 T134 D222 T113 D201 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAADPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1c A 4.50 BS03 ANP A 1 R130 T131 G132 K133 T134 Q135 E163 R170 R310 I329 R109 T110 G111 K112 T113 Q114 E142 R149 R285 I304 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAADPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1c B 4.50 BS01 NUC D 1 L238 S239 R241 Q242 V270 A271 Q272 I287 G288 G289 N290 L217 S218 R220 Q221 V249 A250 Q251 I262 G263 G264 N265 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAADPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1c B 4.50 BS02 NUC E 1 R235 G236 D274 R214 G215 D253 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAADPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1c B 4.50 BS03 ANP A 1 H294 S296 D316 S317 P318 C319 L320 P321 H269 S271 D291 S292 P293 C294 L295 P296 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAADPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h1c C 4.50 BS01 NUC D 1 R229 L238 S239 R241 Q242 I287 G288 G289 I291 R208 L217 S218 R220 Q221 I262 G263 G264 I266 Q06609 PQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAADPKKPIGGNIIAHASTTRLYLRKGRGETRICQIYDSPCLPEAEAMFAINADGVGD 5h7p A BS01 III B 1 Y25 L29 V32 E33 D40 L53 I56 E57 K60 Y25 L29 V32 E33 D40 L53 I56 E57 K60 Q06263 27924850 MASNAARVVATAKDFDKVGLGIIGYYLQLYAVELILSEEDRSQEMTALATELLDTIEAFKKEIGGESEAEDSDKSLHVMNTLIHDQEKAKIYMLNFTMSLYNEKLKQLKDGPWDVMLKRSLWCCIDLFSCILHLWKENISETSTNSLQKRIKYCKIYLSKLAKGEIG 5hl7 A 3.55 BS01 MN A 1 Y6 I9 R13 Y4 I7 R11 P60430 27958389 IKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSIQYDPNRSANIALVVYADGEKRYIIAPKGLEVGQIVESGAEADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGASAQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIV 5hl7 A 3.55 BS02 MG A 1 S223 G235 G237 S221 G233 G235 P60430 27958389 IKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSIQYDPNRSANIALVVYADGEKRYIIAPKGLEVGQIVESGAEADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGASAQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIV 5hl7 C 3.55 BS01 MG C 1 K63 W65 Q67 Q75 K61 W63 Q65 Q73 Q2FW07 27958389 NYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKAQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKK 5hl7 D 3.55 BS01 NUC Y 1 S24 M26 T61 Q63 G86 S20 M22 T57 Q59 G82 Q2FW18 27958389 KEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEAREL 5hl7 I 3.55 BS01 MG I 1 Q54 L55 L57 Q54 L55 L57 P0A0F8 27958389 MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKARSGGGVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLDQLNKFEDGTEVTPALLVESGVVKNEKSGIKILGNGSLDKKLTVKAHKFSAS 5hl7 L 3.55 BS01 NUC Y 1 D6 R11 H15 R30 Y34 R35 S36 N37 K38 H39 Y41 Q43 I45 G50 V51 T52 Q55 T66 A67 D95 Y99 D5 R10 H14 R29 Y33 R34 S35 N36 K37 H38 Y40 Q42 I44 G49 V50 T51 Q54 T65 A66 D94 Y98 Q2FW22 27958389 ISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAE 5hl7 S 3.55 BS01 NUC Y 1 R15 D17 L18 K19 R22 V30 Y32 N38 Q78 H88 D90 L92 R13 D15 L16 K17 R20 V28 Y30 N36 Q76 H86 D88 L90 Q2G0S0 27958389 SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN 5hl7 T 3.55 BS01 MN T 1 E25 K27 E7 K9 Q2FXT0 27958389 KNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAVA 5hzh A 2.60 BS01 GTP A 1 G12 A13 V14 G15 K16 T17 C18 F28 Y32 P34 T35 T207 G209 K265 D267 L268 S307 A308 L309 G10 A11 V12 G13 K14 T15 C16 F26 Y28 P30 T31 T200 G202 K258 D260 L261 S300 A301 L302 P63000 AIKCVVVGDGAVGKTCLLISYTTNAFPYIPTVFDNYSANVMVDGSTTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNARFLQGPETDRATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDAAEREGVMLIKKTAENIDEAAKELGSGGKPVNLGLWDTAGLEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC 5hzh A 2.60 BS02 FMN A 1 V63 T65 N72 N96 A97 R98 L100 Q101 V110 I113 R114 I117 L127 N129 N139 F141 L143 F156 I157 G158 Q160 V56 T58 N65 N89 A90 R91 L93 Q94 V103 I106 R107 I110 L120 N122 N132 F134 L136 F149 I150 G151 Q153 P63000 AIKCVVVGDGAVGKTCLLISYTTNAFPYIPTVFDNYSANVMVDGSTTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNARFLQGPETDRATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDAAEREGVMLIKKTAENIDEAAKELGSGGKPVNLGLWDTAGLEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC 5hzh A 2.60 BS03 MG A 1 T17 T35 D206 T15 T31 D199 P63000 AIKCVVVGDGAVGKTCLLISYTTNAFPYIPTVFDNYSANVMVDGSTTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNARFLQGPETDRATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDAAEREGVMLIKKTAENIDEAAKELGSGGKPVNLGLWDTAGLEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC 5hzi A 2.60 BS01 FMN A 1 V1321 T1323 N1330 N1354 M1355 R1356 L1358 Q1359 V1368 I1371 R1372 I1375 L1385 N1387 N1397 F1399 L1401 F1414 I1415 G1416 Q1418 V91 T93 N100 N124 M125 R126 L128 Q129 V138 I141 R142 I145 L155 N157 N167 F169 L171 F184 I185 G186 Q188 Q15811 LTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGELATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNMRFLQGPETDRATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDAAEREGVMLIKKTAENIDEAAKELKMPVKMIGDILSAQLPHMQPYIRFCSRQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITVFSPKSNLQYKMYKTPIFLNEVLVKLPPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKK 5hzk A 3.30 BS01 GDP A 1 D11 A13 V14 G15 K16 T17 C18 F28 Q116 D118 L119 S158 A159 L160 D9 A11 V12 G13 K14 T15 C16 F26 Q114 D116 L117 S156 A157 L158 P60953 TIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALE 5i4f A 1.55 BS01 6DM A 1 V169 H170 S171 T236 H237 V155 H156 S157 T222 H223 MEIQLQQSGPELVKPGASVKISCKASGYSFTDYIMLWVKQSHGKSLEWIGNINPYYGSTSYNLKFKGKATLTVDKSSSTAYMQLNSLTSEDSAVYYCARKNYYGSSLDYWGQGTTLTVSSAKTGSDVVMTQTPFSLPVSLGDQASISCRSSQSLVHSNGNTYLHWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCSQSTHVPYTFGGGTKLEIK 5i77 A 1.80 BS01 CA A 1 I48 P86 I18 P56 A0A023UH08 27154222 VFEWFGSNESGAEFGTNIPGVWGTDYIFPDPSAISTLIDKGMNFFRVQFMMERLLPDSMTGSYDEEYLANLTTVIKAVTDGGAHALVDPHNYGRYNGEIISSTSDFQTFWENLAGQYKDNDLVMFDTNNEYHDMDQDLVLNLNQAAINGIRAAGATSQYIFVEGNSWTGAWTWVDVNDNMKNLTDPEDKIVYEMHQYLDSDGSGTSETCVSETIGKERVTEATQWLKDNKKVGFIGEYAGGSNDVCRSAVSGMLEYMANNTDVWKGASWWAAGPWWGDYIFSLEPPDGTAYTGMLDILEAYL 5i77 A 1.80 BS02 PEG A 1 Y122 E160 Y227 E267 Y92 E130 Y197 E237 A0A023UH08 27154222 VFEWFGSNESGAEFGTNIPGVWGTDYIFPDPSAISTLIDKGMNFFRVQFMMERLLPDSMTGSYDEEYLANLTTVIKAVTDGGAHALVDPHNYGRYNGEIISSTSDFQTFWENLAGQYKDNDLVMFDTNNEYHDMDQDLVLNLNQAAINGIRAAGATSQYIFVEGNSWTGAWTWVDVNDNMKNLTDPEDKIVYEMHQYLDSDGSGTSETCVSETIGKERVTEATQWLKDNKKVGFIGEYAGGSNDVCRSAVSGMLEYMANNTDVWKGASWWAAGPWWGDYIFSLEPPDGTAYTGMLDILEAYL 5i78 A 1.58 BS01 CA A 1 E29 L332 E2 L305 A0A023UH08 27154222 AEFVFEWFGSNESGAEFGTNIPGVWGTDYIFPDPSAISTLIDKGMNFFRVQFMMERLLPDSMTGSYDEEYLANLTTVIKAVTDGGAHALVDPHNYGRYNGEIISSTSDFQTFWENLAGQYKDNDLVMFDTNNEYHDMDQDLVLNLNQAAINGIRAAGATSQYIFVEGNSWTGAWTWVDVNDNMKNLTDPEDKIVYEMHQYLDSDGSGTSETCVSETIGKERVTEATQWLKDNKKVGFIGAYAGGSNDVCRSAVSGMLEYMANNTDVWKGASWWAAGPWWGDYIFSLEPPDGTAYTGMLDILEAYL 5i79 A 2.35 BS01 CTT A 1 E43 F44 G45 T54 D55 H120 Y122 N159 E160 Y227 S233 G234 W300 W306 E13 F14 G15 T24 D25 H90 Y92 N129 E130 Y197 S203 G204 W270 W276 A0A023UH08 27154222 VFEWFGSNESGAEFGTNIPGVWGTDYIFPDPSAISTLIDKGMNFFRVQFMMERLLPDSMTGSYDEEYLANLTTVIKAVTDGGAHALVDPHNYGRYNGEIISSTSDFQTFWENLAGQYKDNDLVMFDTNNEYHDMDQDLVLNLNQAAINGIRAAGATSQYIFVEGNSWTGAWTWVDVNDNMKNLTDPEDKIVYEMHQYLDSDGSGTSETCVSETIGKERVTEATQWLKDNKKVGFIGAYAGGSNDVCRSAVSGMLEYMANNTDVWKGASWWAAGPWWGDYIFSLEPPDGTAYTGMLDILEAYL 5i79 B 2.35 BS02 CA B 1 E329 A330 L332 E301 A302 L304 A0A023UH08 27154222 EFVFEWFGSNESGAEFGTNIPGVWGTDYIFPDPSAISTLIDKGMNFFRVQFMMERLLPDSMTGSYDEEYLANLTTVIKAVTDGGAHALVDPHNYGRYNGEIISSTSDFQTFWENLAGQYKDNDLVMFDTNNEYHDMDQDLVLNLNQAAINGIRAAGATSQYIFVEGNSWTGAWTWVDVNDNMKNLTDPEDKIVYEMHQYLDSDGSGTSETCVSETIGKERVTEATQWLKDNKKVGFIGAYAGGSNDVCRSAVSGMLEYMANNTDVWKGASWWAAGPWWGDYIFSLEPPDGTAYTGMLDILEAYL 5icp A 2.18 BS01 69Z A 1 V27 G28 Y32 V35 A50 K52 F97 D98 Y99 A100 N156 L158 D173 R356 V27 G28 Y32 V35 A50 K52 F97 D98 Y99 A100 N149 L151 D166 R337 2.7.11.22,2.7.11.23 P49336 27490956 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQESNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEE 5ict A 1.68 BS01 GLU A 1 Y66 A95 M96 T97 R102 L144 G147 S148 T149 E198 Y66 A95 M96 T97 R102 L144 G147 S148 T149 E198 Q03445 27889096 GSYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKGTPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSVHTTDEGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTEC 5idp A 2.65 BS01 6A6 A 1 V27 G28 Y32 V35 A50 F97 D98 Y99 A100 D103 A155 N156 L158 D173 R356 V28 G29 Y33 V36 A51 F98 D99 Y100 A101 D104 A151 N152 L154 D169 R339 2.7.11.22,2.7.11.23 P49336 27490956 KMDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQETSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFL 5iuj A 3.20 BS01 ACP A 1 E289 N293 H297 S298 D320 T323 F324 K325 G326 H335 G336 L337 E135 N139 H143 S144 D166 T169 F170 K171 G172 H179 G180 L181 2.7.13.3 O34757 KERERLEEKLEDANERIAELVKLEERQRIARDLEDTLGQKLSLIGLKSDLARKLIYKDPEQAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDELINIKQILEAADIMFIYEEEKWPENISLLNENILSMCLKEAVTNVVKHSQAKTCRVDIQQLWKEVVITVSDDGTFKGEENSFSHGLLGMRERLEFANGSLHIDTENGTKLTMAIPN 5iuj A 3.20 BS02 MG A 1 E289 N293 E135 N139 2.7.13.3 O34757 KERERLEEKLEDANERIAELVKLEERQRIARDLEDTLGQKLSLIGLKSDLARKLIYKDPEQAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDELINIKQILEAADIMFIYEEEKWPENISLLNENILSMCLKEAVTNVVKHSQAKTCRVDIQQLWKEVVITVSDDGTFKGEENSFSHGLLGMRERLEFANGSLHIDTENGTKLTMAIPN 5iuj B 3.20 BS01 ACP B 1 E289 N293 K296 H297 S298 D320 T323 F324 K325 G326 S330 H335 G336 L337 T359 E136 N140 K143 H144 S145 D167 T170 F171 K172 G173 S177 H182 G183 L184 T206 2.7.13.3 O34757 RKERERLEEKLEDANERIAELVKLEERQRIARDLEDTLGQKLSLIGLKSDLARKLIYKDPEQAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDELINIKQILEAADIMFIYEEEKWPENISLLNENILSMCLKEAVTNVVKHSQAKTCRVDIQQLWKEVVITVSDDGTFKGEENSFSKGHGLLGMRERLEFANGSLHIDTENGTKLTMAIPNN 5iuk C 2.90 BS01 MG C 1 D9 D54 E56 D10 D55 E57 O34723 SMISIFIAEDQQMLLGALGSLLNLEDDMEVVGKGTTGQDAVDFVKKRQPDVCIMDIEMPGKTGLEAAEELKDTGCKIIILTTFARPGYFQRAIKAGVKGYLLKDSPSEELANAIRSVMNGKRIYAPELMEDL 5ium A 3.16 BS01 ACP A 1 E289 N293 V294 H297 S298 D320 T323 F324 K325 H335 G336 L337 T359 E136 N140 V141 H144 S145 D167 T170 F171 K172 H176 G177 L178 T200 2.7.13.3 O34757 RKERERLEEKLEDANERIAELVKLEERQRIARDLHDTLGQKLSLIGLKSDLARKLIYKDPEQAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDELINIKQILEAADIMFIYEEEKWPENISLLNENILSMCLKEAVTNVVKHSQAKTCRVDIQQLWKEVVITVSDDGTFKGEEHGLLGMRERLEFANGSLHIDTENGTKLTMAIPNN 5ium B 3.16 BS01 ACP B 1 E289 N293 V294 K296 H297 S298 D320 T323 F324 K325 G326 F331 G334 H335 G336 L337 E121 N125 V126 K128 H129 S130 D150 T153 F154 K155 G156 F161 G164 H165 G166 L167 2.7.13.3 O34757 EDANERIAELVKLEERQRIARDLHDTLGQKLSLIGLKSDLARKLIYKDPEQAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDELINIKQILEAAIMFIYEEEENISLLNENILSMCLKEAVTNVVKHSQAKRVDIQQLWKEVVITVSDDGTFKGEENSFSKGHGLLGMRERLEFANGSLHITENLTMAIPNNS 5iun C 2.79 BS02 BEF C 1 D54 I55 E56 T80 T81 K102 D55 I56 E57 T81 T82 K103 O34723 SMISIFIAEDQQMLLGALGSLLNLEDDMEVVGKGTTGQDAVDFVKKRQPDVCIMDIEMPGKTGLEAAEELKDTGCKIIILTTFARPGYFQRAIKAGVKGYLLKDSPSEELANAIRSVMNGKRIYAPELMED 5jmn A 2.50 BS01 FUA A 1 I27 K334 H338 V341 I27 K334 H338 V341 P31224 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFS 5jmn B 2.50 BS01 FUA B 1 I27 L300 H338 V341 I27 L300 H338 V341 P31224 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFS 5jmn C 2.50 BS01 FUA C 1 K334 H338 V341 K334 H338 V341 P31224 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRF 5jqr A 1.81 BS01 HEM A 1 P34 R38 W41 P132 A134 L141 F145 L159 G162 H163 I165 G166 A167 A168 H169 R172 S173 W179 L205 S207 Y235 P33 R37 W40 P131 A133 L140 F144 L158 G161 H162 I164 G165 A166 A167 H168 R171 S172 W178 L204 S206 Y234 1.11.1.11 Q43758 27897163 GKSYPTVSADYQKAVEKAKKKLRGFIAEKRCAPLMLRLAWHSAGTFDKGTKTGGPFGTIKHPAELAHSANNGLDIAVRLLEPLKAEFPILSYADFYQLAGVVAVEVTGGPEVPFHPGREDKPEPPPEGRLPDATKGSDHLRDVFGKAMGLTDQDIVALSGGHTIGAAHKERSGFEGPWTSNPLIFDNSYFTELLSGEKEGLLQLPSDKALLSDPVFRPLVDKYAADEDAFFADYAEAHQKLSELGFADA 5jrh A 1.64 BS01 COA A 1 F163 G164 G165 R191 D306 S523 H525 R584 P589 F159 G160 G161 R187 D302 S519 H521 R580 P585 6.2.1.1 Q8ZKF6 HKHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDLGDTSTLADPGVVEKLLEEKQA 5jrh A 1.64 BS02 CMP A 1 G387 E388 P389 D411 T412 W413 W414 Q415 T416 D500 I512 R515 N521 R526 G383 E384 P385 D407 T408 W409 W410 Q411 T412 D496 I508 R511 N517 R522 6.2.1.1 Q8ZKF6 HKHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDLGDTSTLADPGVVEKLLEEKQA 5jrh A 1.64 BS04 BU3 A 1 G173 K270 P271 G169 K266 P267 6.2.1.1 Q8ZKF6 HKHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDLGDTSTLADPGVVEKLLEEKQA 5jrh A 1.64 BS05 BU3 A 2 W97 K106 P143 E144 L220 K221 R222 W93 K102 P139 E140 L216 K217 R218 6.2.1.1 Q8ZKF6 HKHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDLGDTSTLADPGVVEKLLEEKQA 5jrh B 1.64 BS01 COA B 1 F163 G164 G165 R191 I196 D306 P334 N335 A363 P589 F158 G159 G160 R186 I191 D301 P329 N330 A358 P584 6.2.1.1 Q8ZKF6 KHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNLGDTSTLADPGVVEKLLEE 5jrh B 1.64 BS04 BU3 B 1 G173 D177 Y263 K270 P271 G168 D172 Y258 K265 P266 6.2.1.1 Q8ZKF6 KHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNLGDTSTLADPGVVEKLLEE 5jrh B 1.64 BS05 BU3 B 2 W97 K106 P143 E144 R222 W92 K101 P138 E139 R217 6.2.1.1 Q8ZKF6 KHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGKILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNLGDTSTLADPGVVEKLLEE 5jy6 A 2.00 BS01 NAD A 1 N8 G9 G11 R12 I13 N33 D34 L35 R78 A96 T97 G98 F99 F100 T121 A122 C152 N316 Y320 N7 G8 G10 R11 I12 N32 D33 L34 R77 A95 T96 G97 F98 F99 T120 A121 C151 N315 Y319 1.2.1.- Q9ALW2 27875551 VVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIA 5jy6 A 2.00 BS02 MG A 1 I21 V24 V27 I20 V23 V26 1.2.1.- Q9ALW2 27875551 VVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIA 5jya A 2.85 BS01 NAD A 1 G9 G11 R12 I13 D34 L35 R78 A96 T97 G98 F99 F100 T121 A122 S152 N316 Y320 G7 G9 R10 I11 D32 L33 R76 A94 T95 G96 F97 F98 T118 A119 S149 N311 Y315 1.2.1.- Q9ALW2 27875551 VKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHEGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASSTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIA 5jya A 2.85 BS02 G3H A 1 S151 S152 T153 H179 T212 G213 R235 S148 S149 T150 H176 T209 G210 R230 1.2.1.- Q9ALW2 27875551 VKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHEGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASSTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIA 5jya B 2.85 BS02 G3H B 1 S151 S152 T153 H179 D184 G213 S150 S151 T152 H178 D183 G212 1.2.1.- Q9ALW2 27875551 VVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASSTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIA 5jya C 2.85 BS02 G3H C 1 S151 S152 T153 H179 T212 G213 S150 S151 T152 H178 T211 G212 1.2.1.- Q9ALW2 27875551 VVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASSTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIAK 5jye A 2.23 BS01 NAD A 1 G9 F10 G11 R12 I13 D34 L35 R78 A96 T97 G98 F99 F100 T121 A122 C152 N316 Y320 G8 F9 G10 R11 I12 D33 L34 R77 A95 T96 G97 F98 F99 T120 A121 C151 N315 Y319 1.2.1.- Q9ALW2 27875551 VVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIA 5k1i A 2.61 BS01 6PT A 1 Y159 M273 L319 N321 W332 I336 M337 F340 M357 S368 Q369 F372 Y73 M187 L230 N232 W243 I247 M248 F251 M268 S279 Q280 F283 3.1.4.53 Q08499 27933955 EQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 5k1i B 2.61 BS01 6PT B 1 Y159 H160 M273 L319 N321 W332 T333 I336 M337 F340 M357 S368 Q369 F372 Y74 H75 M188 L234 N236 W247 T248 I251 M252 F255 M272 S283 Q284 F287 3.1.4.53 Q08499 27933955 TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 5k1i B 2.61 BS03 MG B 1 D201 H233 D116 H148 3.1.4.53 Q08499 27933955 TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 5k1i D 2.61 BS01 6PT D 1 Y159 M273 L319 N321 W332 T333 I336 M337 F340 S368 Q369 F372 Y74 M188 L234 N236 W247 T248 I251 M252 F255 S283 Q284 F287 3.1.4.53 Q08499 27933955 TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 5k7h A 2.35 BS01 IVC A 1 W169 K172 W173 F174 K175 G178 R179 L180 W156 K159 W160 F161 K162 G165 R166 L167 Q1D4I5 27940564 RYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5k7h A 2.35 BS02 IVC B 1 M69 F72 D128 K131 K132 Y134 V135 T157 F161 L168 M56 F59 D115 K118 K119 Y121 V122 T144 F148 L155 Q1D4I5 27940564 RYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5k7h B 2.35 BS01 IVC A 1 M69 F72 D128 K131 K132 Y134 D136 F161 L168 M56 F59 D115 K118 K119 Y121 D123 F148 L155 Q1D4I5 27940564 RYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5kcl A 2.10 BS01 6C7 A 1 K95 R104 K188 Y190 R264 K266 Y344 N411 Y413 K85 R94 K178 Y180 R254 K256 Y321 N388 Y390 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLRLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kcl B 2.10 BS01 6C7 B 1 K95 R104 K188 Y190 R264 K266 Y268 Q342 Y344 N411 Y413 K85 R94 K178 Y180 R254 K256 Y258 Q318 Y320 N387 Y389 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kcq A 2.00 BS01 GST A 1 E91 R104 K188 Y190 Y268 Q342 Y344 N411 Y413 E81 R94 K178 Y180 Y258 Q319 Y321 N388 Y390 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLRLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kcq B 2.00 BS01 GST B 1 R104 K188 Y190 R264 K266 Y268 N328 Q342 Y344 W397 N411 Y413 R94 K178 Y180 R254 K256 Y258 N304 Q318 Y320 W373 N387 Y389 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kcy A 2.30 BS01 XBU A 1 H88 E91 S177 Y190 L252 L323 R396 W397 H61 E64 S150 Y163 L225 L283 R356 W357 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLRLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kcy A 2.30 BS02 GST A 1 K95 R104 Y190 R264 K266 Y268 A270 F325 G326 N328 Q342 Y344 W397 Y413 K68 R77 Y163 R237 K239 Y241 A243 F285 G286 N288 Q302 Y304 W357 Y373 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLRLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kcy B 2.30 BS01 XBU B 1 H88 E91 C175 S177 P324 R396 W397 H64 E67 C151 S153 P288 R360 W361 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLKLLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kcy B 2.30 BS02 GST B 1 K95 R104 K188 Y190 R264 K266 Y268 L269 G326 N328 Q342 Y344 W397 Y413 K71 R80 K164 Y166 R240 K242 Y244 L245 G290 N292 Q306 Y308 W361 Y377 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLKLLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kd0 A 2.82 BS01 XBU A 1 L83 A91 S93 R104 G106 S177 R396 W397 Y413 L73 A81 S83 R94 G96 S167 R373 W374 Y390 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLAISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLRLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kd0 A 2.82 BS02 GST A 1 K95 R104 K188 Y190 R264 K266 Y268 G326 Y344 W397 N411 Y413 K85 R94 K178 Y180 R254 K256 Y258 G303 Y321 W374 N388 Y390 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLAISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLRLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kd0 B 2.82 BS01 GST B 1 K95 R104 K188 Y190 R264 K266 Y268 G326 Q342 Y344 W397 Y413 K85 R94 K178 Y180 R254 K256 Y258 G302 Q318 Y320 W373 Y389 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLAISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kd6 A 1.84 BS01 6C7 A 1 E91 K95 R104 K188 Y190 R264 K266 N328 Q342 Y344 N411 Y413 E83 K87 R96 K180 Y182 R256 K258 N307 Q321 Y323 N390 Y392 GSRPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLRLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kd6 B 1.84 BS01 LBU B 1 G82 L83 S170 N172 V174 C175 L323 R396 W397 G74 L75 S162 N164 V166 C167 L301 R374 W375 GSRPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kd6 B 1.84 BS02 6C7 B 1 K95 R104 K188 Y190 R264 N328 Q342 Y344 N411 Y413 K87 R96 K180 Y182 R256 N306 Q320 Y322 N389 Y391 GSRPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kda A 2.00 BS01 GEN A 1 G82 E169 R396 W397 G74 E161 R375 W376 GSRPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLRLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kda A 2.00 BS02 6C7 A 1 R104 K188 Y190 Q342 Y344 N411 Y413 R96 K180 Y182 Q321 Y323 N390 Y392 GSRPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLRLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kda B 2.00 BS01 6C7 B 1 R104 K188 Y190 R264 Q342 Y344 N411 Y413 R94 K178 Y180 R254 Q318 Y320 N387 Y389 RPWQILSQALGFPNYDQELWWQNTAETLNRVLEQCDYSVHLQYKYLAFYHKYILPSLGPFRRPGVEPEYISGLSHGGHPLEISVKIDKSKTICRLGLQAIGPLAGTARDPLNSFGDRELLKNLATLLPHVDLRLFDHFNAQVGLDRAQCAVATTKLIKESHNIVCTSLDLKDGEVIPKVYFSTIPKGLVTETPLFDLTFAAIEQMEVYHKDAPLRTALSSLKDFLRPRVPTDASITPPLTGLIGVDCIDPMLSRLKVYLATFRMDLSLIRDYWTLGGLLTDAGTMKGLEMVETLAKTLLPFGINYAMKPGTAELAPPQIYFPLLGINDGFIADALVEFFQYMGWEDQANRYKDELKAKFPNVDISQTKNVHRWLGVAYSETKGPSMNIYYDVVAGNV 5kpn A 2.30 BS01 6WX A 1 D766 D770 H862 G863 R878 A880 Y889 G894 I895 Y896 F897 S904 Y907 E988 D106 D110 H202 G203 R218 A220 Y229 G234 I235 Y236 F237 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5kpn B 2.30 BS01 6WX B 1 D766 L769 H862 G863 L877 R878 I879 A880 G894 I895 Y896 F897 S904 Y907 E988 D105 L108 H201 G202 L216 R217 I218 A219 G233 I234 Y235 F236 S243 Y246 E327 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5kpo A 2.65 BS01 6WY A 1 D766 L769 H862 G863 R878 Y889 G894 I895 Y896 F897 S904 Y907 E988 D106 L109 H202 G203 R218 Y229 G234 I235 Y236 F237 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5kpo B 2.65 BS01 6WY B 1 D766 D770 H862 G863 L877 R878 Y889 G894 I895 Y896 F897 S904 Y907 E988 D105 D109 H201 G202 L216 R217 Y228 G233 I234 Y235 F236 S243 Y246 E327 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5kyt A 2.00 BS01 SLU A 1 H245 G246 F247 T251 G315 G316 A317 P318 Q338 G339 Y340 G341 L342 T343 S347 A348 V362 D422 R437 K529 H242 G243 F244 T248 G312 G313 A314 P315 Q335 G336 Y337 G338 L339 T340 S344 A345 V359 D419 R434 K518 1.13.12.7 P08659 27861940 AKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQTALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPFDAGVAGLPDDDAGELPAAVVVLEEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAK 5kyt B 2.00 BS01 SLU B 1 H245 G246 F247 T251 G315 G316 A317 P318 Q338 G339 Y340 G341 L342 T343 T346 S347 A348 D422 R437 K529 H238 G239 F240 T244 G308 G309 A310 P311 Q331 G332 Y333 G334 L335 T336 T339 S340 A341 D415 R430 K522 1.13.12.7 27861940 AKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQTALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAKKGGKSKL 5kyv A 2.50 BS01 SLU A 1 H245 A246 F247 T251 A313 G315 G316 A317 P318 Q338 G339 Y340 G341 L342 T343 S347 A348 V362 D422 R437 L526 H238 A239 F240 T244 A306 G308 G309 A310 P311 Q331 G332 Y333 G334 L335 T336 S340 A341 V355 D415 R430 L513 1.13.12.7 P08659 AKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVIPFHHAFGMSTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHFDAGVAGLPDDDAGELPAAVVVLKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAK 5kyv B 2.50 BS01 SLU B 1 H245 A246 F247 T251 G315 G316 A317 P318 G339 Y340 G341 L342 T343 S347 A348 D422 I434 R437 K529 H238 A239 F240 T244 G308 G309 A310 P311 G332 Y333 G334 L335 T336 S340 A341 D415 I427 R430 K522 1.13.12.7 P08659 AKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVIPFHHAFGMSTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAKKGGKSKL 5l2l A 1.55 BS01 NUC C 1 K416 F417 H420 C421 T422 N423 E456 D457 C458 R459 F460 N463 C464 K465 F471 K9 F10 H13 C14 T15 N16 E49 D50 C51 R52 F53 N56 C57 K58 F64 27932457 SEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVL 5l2l A 1.55 BS02 NUC D 1 T419 R432 H434 I435 C437 R438 R445 D447 C448 L449 F450 T12 R25 H27 I28 C30 R31 R38 D40 C41 L42 F43 27932457 SEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVL 5l2l A 1.55 BS03 NUC G 1 E413 Q414 C415 K416 F417 T422 N423 K424 R425 Y428 E6 Q7 C8 K9 F10 T15 N16 K17 R18 Y21 27932457 SEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVL 5l2l A 1.55 BS04 ZN A 1 C415 C421 C426 H430 C8 C14 C19 H23 27932457 SEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVL 5l2l B 1.55 BS01 NUC C 1 T419 H420 R432 H434 I435 M436 C437 R438 R445 D447 C448 L449 F450 T13 H14 R26 H28 I29 M30 C31 R32 R39 D41 C42 L43 F44 27932457 GSEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVLP 5l2l B 1.55 BS03 NUC H 1 Q414 C415 K416 F417 T422 N423 K424 R425 K427 Y428 Q8 C9 K10 F11 T16 N17 K18 R19 K21 Y22 27932457 GSEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVLP 5l2l E 1.55 BS01 NUC D 1 E413 Q414 C415 K416 F417 T422 N423 R425 K427 Y428 E5 Q6 C7 K8 F9 T14 N15 R17 K19 Y20 27932457 EKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVLP 5l2l E 1.55 BS02 NUC G 1 T419 R432 I435 M436 C437 R438 R445 D447 C448 L449 F450 T11 R24 I27 M28 C29 R30 R37 D39 C40 L41 F42 27932457 EKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVLP 5l2l F 1.55 BS01 NUC C 1 Q414 C415 K416 F417 T422 N423 R425 Y428 Q8 C9 K10 F11 T16 N17 R19 Y22 27932457 GSEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVLPE 5l3u E 1.23 BS06 6NG E 1 N112 A113 F114 N116 L133 V139 H142 E143 H146 Y157 E166 L202 R203 H231 N112 A113 F114 N116 L133 V139 H142 E143 H146 Y157 E166 L202 R203 H231 3.4.24.27 P00800 27933956 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 5l47 B 3.30 BS01 6JA B 1 T226 S230 I233 T222 S226 I229 Q7NDN8 VSPPPPIADEPLTVNTGIYLIESYSLDDCAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNCPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5l4e B 3.50 BS01 EDP D 1 T226 S230 T222 S226 Q7NDN8 VSPPPPIADEPLTVNTGIYLIESYSLDDCAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNCPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5l7t A 1.98 BS02 6QJ A 1 H93 P96 S141 V143 Q148 A149 Y154 N186 W192 L195 H90 P93 S138 V140 Q145 A146 Y151 N183 W189 L192 1.1.1.- Q9BPX1 27933965 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKPSG 5l7w A 1.76 BS02 6QU A 1 H93 S141 V143 Q148 A149 Q150 Y154 N186 W192 L195 H90 S138 V140 Q145 A146 Q147 Y151 N183 W189 L192 1.1.1.- Q9BPX1 27933965 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGPSG 5l7w A 1.76 BS03 BGC A 1 G20 W188 T189 P190 E193 P221 G17 W185 T186 P187 E190 P218 1.1.1.- Q9BPX1 27933965 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGPSG 5l7y A 1.91 BS02 6QO A 1 G18 R27 S44 G45 A48 G15 R24 S41 G42 A45 1.1.1.- Q9BPX1 27933965 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKPSG 5li6 A 1.95 BS01 HEM A 1 L95 N96 H103 R107 M157 G254 T257 T258 S261 P299 K303 R305 G355 F356 G357 H361 C363 G365 A369 L89 N90 H97 R101 M151 G219 T222 T223 S226 P264 K268 R270 G320 F321 G322 H326 C328 G330 A334 1.14.-.- P9WPN8 LSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVDAGSRLYTYALELIAGKRAEPADDMLSVVANALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELR 5li6 A 1.95 BS02 6XF A 1 V84 L88 V90 N96 M97 L249 L250 A253 G254 T257 S300 K303 R400 H401 V78 L82 V84 N90 M91 L214 L215 A218 G219 T222 S265 K268 R365 H366 1.14.-.- P9WPN8 LSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVDAGSRLYTYALELIAGKRAEPADDMLSVVANALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELR 5li6 B 1.95 BS01 HEM B 1 L95 N96 H103 R107 M157 L161 T257 T258 P299 K303 R305 G355 F356 G357 H361 C363 G365 A369 L89 N90 H97 R101 M151 L155 T221 T222 P263 K267 R269 G319 F320 G321 H325 C327 G329 A333 1.14.-.- P9WPN8 LSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVAGSRLYTYALELIAGKRAEPADDMLSVVANALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELR 5li6 B 1.95 BS02 6XF B 1 V84 L88 N96 M97 L249 A253 G254 T257 S300 K303 R400 H401 V78 L82 N90 M91 L213 A217 G218 T221 S264 K267 R364 H365 1.14.-.- P9WPN8 LSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVAGSRLYTYALELIAGKRAEPADDMLSVVANALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELR 5li7 A 1.58 BS01 HEM A 1 L95 N96 H103 R107 M157 L249 A253 T257 T258 S261 P299 K303 R305 G355 F356 G357 H361 C363 G365 A369 L89 N90 H97 R101 M151 L210 A214 T218 T219 S222 P260 K264 R266 G316 F317 G318 H322 C324 G326 A330 1.14.-.- P9WPN8 LSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVRLYTYALELIAGKRAEPADDMLSVVANALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELR 5li7 A 1.58 BS02 6XD A 1 N96 L245 H248 L249 S252 A253 T257 N90 L206 H209 L210 S213 A214 T218 1.14.-.- P9WPN8 LSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVRLYTYALELIAGKRAEPADDMLSVVANALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELR 5li8 A 1.83 BS01 HEM A 1 L95 N96 H103 R107 M157 L161 L250 T257 T258 S261 P299 K303 R305 G355 F356 G357 H361 C363 G365 A369 L85 N86 H93 R97 M147 L151 L226 T233 T234 S237 P275 K279 R281 G331 F332 G333 H337 C339 G341 A345 1.14.-.- P9WPN8 GLSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVEPLNVEDAGSRLYTYALELIAGKRAEPADDMLSVVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELRGG 5li8 A 1.83 BS02 KKK A 1 T13 P46 V94 N96 F246 A253 S302 K303 R304 N399 R400 T8 P41 V84 N86 F222 A229 S278 K279 R280 N375 R376 1.14.-.- P9WPN8 GLSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVEPLNVEDAGSRLYTYALELIAGKRAEPADDMLSVVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELRGG 5lie A 1.80 BS02 IMD A 1 L249 A253 T257 L216 A220 T224 1.14.-.- P9WPN8 LSGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVVEDAGSRLYTYALELIAGKRAEPADDMLSVVANALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELR 5lie B 1.80 BS01 HEM B 1 N96 H103 R107 M157 I158 L161 A253 G254 T257 T258 S261 P299 K303 R305 E328 G355 F356 G357 H361 C363 G365 L368 A369 N89 H96 R100 M150 I151 L154 A238 G239 T242 T243 S246 P284 K288 R290 E313 G340 F341 G342 H346 C348 G350 L353 A354 1.14.-.- P9WPN8 SGIDLTDLDNFADGFPHHLFAIHRREAPVYWHRPTEHTPDGEGFWSVATYAETLEVLRDPVTYSSVTGGQRRFGGTVLQDLPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVEDDLRRRARGLLDGVEPGAPFDFVVEIAAELPMQMICILLGVPETDRHWLFEAVEPGFDFRGSRRATMPRLNVEDAGSRLYTYALELIAGKRAEPADDMLSVVANPALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFELLPTAIEEIVRWTSPSPSKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELR 5lif E 1.31 BS06 6XO E 1 N112 A113 F114 W115 N116 F130 L133 V139 H142 E143 H146 Y157 E166 L202 R203 H231 N112 A113 F114 W115 N116 F130 L133 V139 H142 E143 H146 Y157 E166 L202 R203 H231 3.4.24.27 P00800 27959500 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 5lwd E 1.23 BS06 79E E 1 N111 N112 A113 W115 F130 L133 V139 H142 E143 H146 Y157 E166 L202 R203 H231 N111 N112 A113 W115 F130 L133 V139 H142 E143 H146 Y157 E166 L202 R203 H231 3.4.24.27 P00800 27959500 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 5lxp A 2.07 BS01 7AG A 1 H1682 G1683 Y1714 F1715 A1716 Y1721 S1722 T1726 Y1727 H72 G73 Y95 F96 A97 Y102 S103 T107 Y108 2.4.2.30 Q460N5 27918638 DMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK 5lxp B 2.07 BS01 7AG B 1 H1682 G1683 Y1714 F1715 A1716 Y1721 S1722 Y1727 G1751 T1774 L1782 V1784 H73 G74 Y94 F95 A96 Y101 S102 Y107 G131 T154 L162 V164 2.4.2.30 Q460N5 27918638 MDMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK 5lyh A 2.17 BS01 7B8 A 1 H1682 G1683 T1684 S1688 H1691 F1697 N1698 S1700 V1707 G1712 T1713 Y1714 F1715 A1716 Y1721 S1722 Y1727 H71 G72 T73 S77 H80 F86 N87 S89 V91 G96 T97 Y98 F99 A100 Y105 S106 Y111 2.4.2.30 Q460N5 27918638 MKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK 5lyh B 2.17 BS01 7B8 B 1 H1682 G1683 T1684 S1688 H1691 V1692 S1700 K1711 G1712 Y1714 A1716 Y1721 S1722 Y1727 H70 G71 T72 S76 H79 V80 S88 K92 G93 Y95 A97 Y102 S103 Y108 2.4.2.30 Q460N5 27918638 KQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK 5lyy A 2.17 BS01 7BJ A 1 L107 F110 G152 L153 G154 A155 L159 H272 S273 F274 W298 F322 H351 Q352 A355 F357 L53 F56 G98 L99 G100 A101 L105 H218 S219 F220 W244 F268 H297 Q298 A301 F303 3.1.1.47 Q13093 27933945 KIPRGNGPYSVGCTDLMFDHTNKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNILRLLFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGIDLASHGFIVAAVEHRDRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMFPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFATGKIIGHMLKLKGDIDSNVAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGTNINTT 5lz2 A 2.10 BS01 7BX A 1 F110 G152 L153 G154 A155 L159 Y160 H272 Q352 A355 F357 F56 G98 L99 G100 A101 L105 Y106 H218 Q298 A301 F303 3.1.1.47 Q13093 27933945 KIPRGNGPYSVGCTDLMFDHTNKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNILRLLFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGIDLASHGFIVAAVEHRDRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFRCGIALDAWMFPLGDEVYSRIPQPLFFINSEYFQYPANIIKMKKCYSPDKERKMITIRGSVHQNFADFTFATGKIIGHMLKLKGDIDSNVAIDLSNKASLAFLQKHLGLHKDFDQWDCLIEGDDENLIPGTNINTT 5m3e A 2.50 BS01 APR A 1 G7 N8 L9 T20 N22 K29 G30 V31 A32 Q34 T79 P115 G117 A118 G119 N120 G121 Y147 P149 G9 N10 L11 T22 N24 K31 G32 V33 A34 Q36 T81 P117 G119 A120 G121 N122 G123 Y149 P151 B7A854 27939941 GGMLRFVRGNLLEAPVEALVNTVNTVGVMGKGVALQFKRAFPDNYQAYVKACERGQVQIGRIFVYDRGPLAQPRYIFNFPTKKHWRHPSRMEYVEEGLKDLVCRIQELRVRSIALPPLGAGNGGLPWPEVKQRIQEALEALEGVEVWVYEPV 5m3h A 2.50 BS02 NUC V 1 R279 K281 H326 K328 Y334 W363 G364 G366 E367 G368 Q369 A370 P371 Y388 K389 S390 P392 P393 R503 H505 D511 V512 N514 K534 R561 T562 N563 G564 K569 N691 R264 K266 H311 K313 Y319 W348 G349 G351 E352 G353 Q354 A355 P356 Y373 K374 S375 P377 P378 R488 H490 D496 V497 N499 K519 R546 T547 N548 G549 K554 N676 H6QM92 MENFVRTNFNPMILERAEKTMKEYGENPQNEGNKFAAISTHMEVCFMYSDFHFIDLEGNTIVKENDDDNAMLKHRFEIIEGQERNIAWTIVNSICNMTENSKPRFLPDLYDYKTNKFIEIGVTRRKVEDYYYEKASKLKGENVYIHIFSFDGEEMATDDEYILDEESRARIKTRLFVLRQELATALEEEFSYPPTFQRLANQSLPPSFKDYHQFKAYVSSFKANGNIEAKLGAMSEKVNAQIESFDPRTIRELELPEGKFCTQRSKFLLMDAMKLSVLNPAHEGEGIPMKDAKACLDTFWGWKKATIIKKHEKGVNTNYLMIWEQLLESIKEMEGKFLNLKKTNHLKWGLGEGQAPEKMDFEDCKEVPDLFQYKSEPPEKRKLASWIQSEFNKASELTNSNWIEFDELGNDVAPIEHIASRRRNFFTAEVSQCRASEYIMKAVYINTALLNSSCTAMEEYQVIPIITKCRDTSGQRRTNLYGFIIKGRSHLRNDTDVVNFISLEFSLTDPRNEIHKWEKYCVLEIGDMEIRTSISTIMKPVYLYVRTNGTSKIKMKWGMEMRRCLLQSLQQVESMIEAESAVKEKDMTEPFFRNRENDWPIGESPQGIEKGTIGKVCRVLLAKSVFNSIYASAQLEGFSAESRKLLLLIQAFRDNLDPGTFDLKGLYEAIEECIINDPWVLLNASWFNSFLKAVQLSMG 5m3h A 2.50 BS03 III X 1 L412 F440 A443 E444 Q447 F607 K630 R633 L397 F425 A428 E429 Q432 F592 K615 R618 H6QM92 MENFVRTNFNPMILERAEKTMKEYGENPQNEGNKFAAISTHMEVCFMYSDFHFIDLEGNTIVKENDDDNAMLKHRFEIIEGQERNIAWTIVNSICNMTENSKPRFLPDLYDYKTNKFIEIGVTRRKVEDYYYEKASKLKGENVYIHIFSFDGEEMATDDEYILDEESRARIKTRLFVLRQELATALEEEFSYPPTFQRLANQSLPPSFKDYHQFKAYVSSFKANGNIEAKLGAMSEKVNAQIESFDPRTIRELELPEGKFCTQRSKFLLMDAMKLSVLNPAHEGEGIPMKDAKACLDTFWGWKKATIIKKHEKGVNTNYLMIWEQLLESIKEMEGKFLNLKKTNHLKWGLGEGQAPEKMDFEDCKEVPDLFQYKSEPPEKRKLASWIQSEFNKASELTNSNWIEFDELGNDVAPIEHIASRRRNFFTAEVSQCRASEYIMKAVYINTALLNSSCTAMEEYQVIPIITKCRDTSGQRRTNLYGFIIKGRSHLRNDTDVVNFISLEFSLTDPRNEIHKWEKYCVLEIGDMEIRTSISTIMKPVYLYVRTNGTSKIKMKWGMEMRRCLLQSLQQVESMIEAESAVKEKDMTEPFFRNRENDWPIGESPQGIEKGTIGKVCRVLLAKSVFNSIYASAQLEGFSAESRKLLLLIQAFRDNLDPGTFDLKGLYEAIEECIINDPWVLLNASWFNSFLKAVQLSMG 5m3h A 2.50 BS04 III Y 1 M285 A287 M288 K289 L290 S291 T313 W417 R449 L522 M543 E544 I545 R546 T547 K554 M270 A272 M273 K274 L275 S276 T298 W402 R434 L507 M528 E529 I530 R531 T532 K539 H6QM92 MENFVRTNFNPMILERAEKTMKEYGENPQNEGNKFAAISTHMEVCFMYSDFHFIDLEGNTIVKENDDDNAMLKHRFEIIEGQERNIAWTIVNSICNMTENSKPRFLPDLYDYKTNKFIEIGVTRRKVEDYYYEKASKLKGENVYIHIFSFDGEEMATDDEYILDEESRARIKTRLFVLRQELATALEEEFSYPPTFQRLANQSLPPSFKDYHQFKAYVSSFKANGNIEAKLGAMSEKVNAQIESFDPRTIRELELPEGKFCTQRSKFLLMDAMKLSVLNPAHEGEGIPMKDAKACLDTFWGWKKATIIKKHEKGVNTNYLMIWEQLLESIKEMEGKFLNLKKTNHLKWGLGEGQAPEKMDFEDCKEVPDLFQYKSEPPEKRKLASWIQSEFNKASELTNSNWIEFDELGNDVAPIEHIASRRRNFFTAEVSQCRASEYIMKAVYINTALLNSSCTAMEEYQVIPIITKCRDTSGQRRTNLYGFIIKGRSHLRNDTDVVNFISLEFSLTDPRNEIHKWEKYCVLEIGDMEIRTSISTIMKPVYLYVRTNGTSKIKMKWGMEMRRCLLQSLQQVESMIEAESAVKEKDMTEPFFRNRENDWPIGESPQGIEKGTIGKVCRVLLAKSVFNSIYASAQLEGFSAESRKLLLLIQAFRDNLDPGTFDLKGLYEAIEECIINDPWVLLNASWFNSFLKAVQLSMG 5m3h B 2.50 BS01 NUC R 1 R135 N671 R672 S673 I674 N676 R135 N667 R668 S669 I670 N672 2.7.7.48 H6QM91 MDVNPMLIFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVIRTHDYSSRGIWKTNSETGAQQLNPIDGPLPEDNEPSGYAQTDCVLELIEGLDRSHPGLFETACQETIDAIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRKNGYKLNESGRLIDFLKDVLLSFENDSMEVTTHFQKKKRIRDNKKMITQRTIGKKRVKLTKKNYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVELLARNICERLEQSGLPVGGNEKKAKLANVIKKMMAKSTDEELSYTITGDNTKWNENQNPRIFLAMVLRITAGQPEWFRDLLAVAPIMFSNKVARLGRGYMFESKSMHLRTQISAENLSDINLRYFNEDTKKKIEKIRHLMVEGTASLSPGMMMGMFNMLSTVLGVSVLNLGQREILKRTYWWDGLQSSDDFALIINGHFKEDIQQGVNHFYRTCKLVGINMSQKKSYINKTGTFEFTSFFYRYGFVANFSMELPSFGVAGNNESADMSIGTTVIKTNMINNDLGPATAQMAIQLFIKDYRYTYRCHRGDTNLETRRTKSIKRLWTETISKAGLLVADGGPNPYNLRNLHIPEVCLKWSLMDPDYRGRLCNPNNPFVHHMEVESTNLAVVMPGPAKSLEYDAVATTHSWTPKRNRSILNTNQRGILEDERIYQKCCQVFEKFFPSSTYRRPIGMASMLDAMLSRARIDARIDLESGRISSQDFSEITNTCKAIEALK 5m3h B 2.50 BS02 NUC V 1 H32 G33 T34 Y38 K188 I200 T201 K237 M356 E358 R365 N676 H32 G33 T34 Y38 K188 I198 T199 K235 M354 E356 R363 N672 2.7.7.48 H6QM91 MDVNPMLIFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVIRTHDYSSRGIWKTNSETGAQQLNPIDGPLPEDNEPSGYAQTDCVLELIEGLDRSHPGLFETACQETIDAIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRKNGYKLNESGRLIDFLKDVLLSFENDSMEVTTHFQKKKRIRDNKKMITQRTIGKKRVKLTKKNYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVELLARNICERLEQSGLPVGGNEKKAKLANVIKKMMAKSTDEELSYTITGDNTKWNENQNPRIFLAMVLRITAGQPEWFRDLLAVAPIMFSNKVARLGRGYMFESKSMHLRTQISAENLSDINLRYFNEDTKKKIEKIRHLMVEGTASLSPGMMMGMFNMLSTVLGVSVLNLGQREILKRTYWWDGLQSSDDFALIINGHFKEDIQQGVNHFYRTCKLVGINMSQKKSYINKTGTFEFTSFFYRYGFVANFSMELPSFGVAGNNESADMSIGTTVIKTNMINNDLGPATAQMAIQLFIKDYRYTYRCHRGDTNLETRRTKSIKRLWTETISKAGLLVADGGPNPYNLRNLHIPEVCLKWSLMDPDYRGRLCNPNNPFVHHMEVESTNLAVVMPGPAKSLEYDAVATTHSWTPKRNRSILNTNQRGILEDERIYQKCCQVFEKFFPSSTYRRPIGMASMLDAMLSRARIDARIDLESGRISSQDFSEITNTCKAIEALK 5m3j A 3.50 BS02 NUC V 1 K330 W364 A365 T366 G367 D368 G369 L370 T371 Y372 P391 K392 P394 Q504 H506 D512 V513 T515 R558 V559 N560 G561 Q566 N692 K324 W358 A359 T360 G361 D362 G363 L364 T365 Y366 P385 K386 P388 Q498 H500 D506 V507 T509 R552 V553 N554 G555 Q560 N686 Q5V8Z9 SMDTFITRNFQTTIIQKAKNTMAEFSEDPELQPAMLFNICVHLEVCYVISDMNFLDEEGKAYTAQNLRPQYEVIEGMPRTIAWMVQRSLAQEHGIETPKYLADLFDYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIFSYNQDYSLSNESSLDEEGKGRVLSRLTELQAELSLKNLWQVLIGEEDVEKGIDFKLGQTISRLRDISVPAGFSNFEGMRSYIDNIDPKGAIERNLARMSPLVSVTPKKLTWEDLRPIGPHIYNHELPEVPYNAFLLMSDELGLANMTEGKSKKPKTLAKECLEKYSTLRDQTDPILIMKSEKANENFLWKLWRDCVNTISNEEMSNELQKTNYAKWATGDGLTYQKIMKEVAIDDETMCQEEPKIPNKCRVAAWVQTEMNLLSTLTSKRALDLPEIGPDVAPVEHVGSERRKYFVNEINYCKASTVMMKYVLFHTSLLNESNASMGKYKVIPITNRVVNEKGESFDMLYGLAVKGQSHLRGDTDVVTVVTFEFSSTDPRVDSGKWPKYTVFRIGSLFVSGREKSVYLYCRVNGTNKIQMKWGMEARRCLLQSMQQMEAIVEQESSIQGYDMTKACFKGDRVNSPKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSAESRRLLLLIQALKDRKGPWVFDLEGMYSGIEECISNNPWVIQSAYWFNEWLGFEKEGSKVLESVDE 5m3j A 3.50 BS03 III X 1 T412 L413 T414 S415 K440 Y441 E445 Y448 K605 K631 R634 T406 L407 T408 S409 K434 Y435 E439 Y442 K599 K625 R628 Q5V8Z9 SMDTFITRNFQTTIIQKAKNTMAEFSEDPELQPAMLFNICVHLEVCYVISDMNFLDEEGKAYTAQNLRPQYEVIEGMPRTIAWMVQRSLAQEHGIETPKYLADLFDYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIFSYNQDYSLSNESSLDEEGKGRVLSRLTELQAELSLKNLWQVLIGEEDVEKGIDFKLGQTISRLRDISVPAGFSNFEGMRSYIDNIDPKGAIERNLARMSPLVSVTPKKLTWEDLRPIGPHIYNHELPEVPYNAFLLMSDELGLANMTEGKSKKPKTLAKECLEKYSTLRDQTDPILIMKSEKANENFLWKLWRDCVNTISNEEMSNELQKTNYAKWATGDGLTYQKIMKEVAIDDETMCQEEPKIPNKCRVAAWVQTEMNLLSTLTSKRALDLPEIGPDVAPVEHVGSERRKYFVNEINYCKASTVMMKYVLFHTSLLNESNASMGKYKVIPITNRVVNEKGESFDMLYGLAVKGQSHLRGDTDVVTVVTFEFSSTDPRVDSGKWPKYTVFRIGSLFVSGREKSVYLYCRVNGTNKIQMKWGMEARRCLLQSMQQMEAIVEQESSIQGYDMTKACFKGDRVNSPKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSAESRRLLLLIQALKDRKGPWVFDLEGMYSGIEECISNNPWVIQSAYWFNEWLGFEKEGSKVLESVDE 5m3j C 3.50 BS01 NUC R 1 T38 S39 R40 E42 R48 W51 T38 S39 R40 E42 R48 W51 Q5V8X3 MTLAKIELLKQLLRDNEAKTVLKQTTVDQYNIIRKFNTSRIEKNPSLRMKWAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVTWWNTYGPIGDTEGFERVYESFFLRKMRLDNATWGRITFGPVERVRKRVLLNPLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTMITPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPGGNKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSCLAAIDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIGNGTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDLIILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFDQWGYEESPKASELHGINESMNASDYTLKGVVVTRNVKVSITKNLSLIKRTGEVIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQNTYQWVLKNLVTLKAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARAVLKQMRDQEVMKTDQFIKLLPFCFSPPKLRSNGEPYQFLKLVLKGGGENFIEVRKGSPLFSYNPQTEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPDLGDFKTIEELEKLKPGEKANILLYQGKPVKVVK 5m5x A 4.00 BS01 NUC R 1 S371 N380 R591 D631 S301 N304 R505 D545 2.7.7.6 P10964 27867008 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSHENSQNQLLSKVLTTSLLIRDLNDDLSKLRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 5m5x A 4.00 BS02 NUC S 1 Y95 R99 H221 R446 T1228 Q1601 Y95 R99 H192 R360 T1128 Q1393 2.7.7.6 P10964 27867008 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSHENSQNQLLSKVLTTSLLIRDLNDDLSKLRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 5m5x A 4.00 BS03 NUC T 1 S229 F248 K259 H378 T441 E464 R475 R481 Q592 P593 T1013 S1014 Y1018 E1616 T1617 S200 F219 K230 H302 T355 E378 R389 R395 Q506 P507 T927 S928 Y932 E1408 T1409 2.7.7.6 P10964 27867008 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSHENSQNQLLSKVLTTSLLIRDLNDDLSKLRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 5m5x A 4.00 BS05 ZN A 2 G55 C62 C65 C72 H75 G55 C62 C65 C72 H75 2.7.7.6 P10964 27867008 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSHENSQNQLLSKVLTTSLLIRDLNDDLSKLRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 5m5x B 4.00 BS01 NUC R 1 R204 S482 G483 R495 S507 P538 Q720 Q724 H875 K916 K924 H1038 V1060 R1065 R183 S461 G462 R474 S486 P517 Q699 Q703 H849 K890 K898 H1012 V1034 R1039 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m5x B 4.00 BS02 NUC S 1 R219 P220 S221 S263 R444 S447 R448 M451 Q479 F508 R198 P199 S200 S242 R423 S426 R427 M430 Q458 F487 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m5x B 4.00 BS03 NUC T 1 I199 N423 M430 R452 N454 Y463 S466 T467 K513 N739 Q1045 G1062 R1063 K1064 R1070 M1074 I178 N402 M409 R431 N433 Y442 S445 T446 K492 N718 Q1019 G1036 R1037 K1038 R1044 M1048 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m5x B 4.00 BS04 ZN B 1 C1104 E1106 C1107 C1128 C1131 C1078 E1080 C1081 C1102 C1105 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m5x I 4.00 BS01 ZN I 1 C10 C13 C30 C9 C12 C29 P32529 27867008 SVVGSLIFCLDCGDLLENPNAVLGSNVECSQCKAIYPKSQFSNLKVVTTTADDAFPSSLRAKKS 5m5y A 4.00 BS01 NUC R 1 D629 D631 D549 D551 2.7.7.6 P10964 27867008 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 5m5y A 4.00 BS02 NUC S 1 R99 R244 T1228 Q1601 R99 R215 T1134 Q1404 2.7.7.6 P10964 27867008 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 5m5y A 4.00 BS03 NUC T 1 F248 E464 R468 R475 Y1018 E1616 T1617 C1619 Q1620 F219 E384 R388 R395 Y938 E1419 T1420 C1422 Q1423 2.7.7.6 P10964 27867008 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 5m5y B 4.00 BS01 NUC R 1 R204 G483 S507 Y717 Q720 K916 K924 R1037 R183 G462 S486 Y696 Q699 K890 K898 R1011 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m5y B 4.00 BS02 NUC S 1 R219 S221 F508 Q511 R198 S200 F487 Q490 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m5y B 4.00 BS03 NUC T 1 Q1045 G1062 R1063 K1064 R1070 Q1019 G1036 R1037 K1038 R1044 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m64 A 4.60 BS01 NUC S 1 K225 K245 T1228 A1229 Q1601 K196 K216 T1134 A1135 Q1404 2.7.7.6 P10964 27867008 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 5m64 A 4.60 BS02 NUC T 1 R230 F248 E464 Q592 P593 T1013 S1014 Y1018 R1021 R1600 E1616 T1617 R201 F219 E384 Q512 P513 T933 S934 Y938 R941 R1403 E1419 T1420 2.7.7.6 P10964 27867008 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 5m64 B 4.60 BS01 NUC S 1 R219 S221 F508 K513 R198 S200 F487 K492 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m64 B 4.60 BS02 NUC T 1 K1061 G1062 R1063 K1064 R1070 M1074 K1035 G1036 R1037 K1038 R1044 M1048 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m64 B 4.60 BS03 NUC R 1 S482 G483 S507 D535 Q720 S461 G462 S486 D514 Q699 2.7.7.6 P22138 27867008 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNISNSGYLGNKLSVSVEQVSIAKPMSNDVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 5m64 I 4.60 BS01 ZN I 1 C13 C30 C12 C29 P32529 27867008 SVVGSLIFCLDCGDLLENPNAVLGSNVECSQCKAIYPKSQFSNLKVVTTTADDAFPSSLRAKKS 5m64 L 4.60 BS01 ZN L 1 C31 C34 C48 D50 C51 C4 C7 C21 D23 C24 P40422 27867008 KYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR 5meh A 0.95 BS01 DMJ A 1 I124 L310 R363 P364 E365 Y423 E427 T451 E452 I100 L286 R339 P340 E341 Y399 E403 T427 E428 3.2.1.113 B0SWV2 ASETTPEDWKALAADVRSEFQWAWQGYVAKAWGKDEINPVSGTSRSFFIEGHDLGLSLVEALDTLWIMGLDAEFQAGVDWVKANLSFDVDGNAQVFETNIRLVGGLLSAHLASGDPVLLAKARDLADRLAKAFEASPHGLPWRYVNLRTGAVSDPETNLAEIGTYLSEFGVLSQLTGERKYFDMAKRAMRHTLDRRSKIGLMAANIHAMTGAFTSRNASIDVYADSFYEYLWDAWALFGDEDCKRWAVECVDAQLAHQAKRYDGRLWFPMVDFETGAVTGTAQSELAAYYAGLLGQVGRKAQGDDYLASFTYLQATFGVIPESIDVTTGQPRRKHTGLRPEYPDACLNLWLIDRDPRYRRLAAIHYREMKATSRAAFGYTALKDITTRPMTQDDNCPGYWWSEQMKYYYLLFSDTPRIDYGQLQLSTEANVLRGFRKV 5mf5 A 1.77 BS01 C2E A 1 Q25 E39 L41 M42 R43 R53 P54 D55 L74 N98 D160 D161 Q184 G218 E220 G238 Y239 P244 Q21 E35 L37 M38 R39 R49 P50 D51 L70 N94 D156 D157 Q180 G214 E216 G234 Y235 P240 A0A140SMD7 ASPSSELRRALEANEFIPYYQPLSPGQGGRWIGVEVLMRWRHPREGLIRPDLFIPFAERSGLIVPMTRALMRQVAEDLGGHAGKLEPGFHIGFNISATHCHELALVDDCRELLAAFPPGHITLVLELTERELIESSEVTDRLFDELHALGVKIAIDDFGTGHSSLAYLRKFQVDCLKIDQSFVARIGIDTLSGHILDSIVELSAKLDLDIVAEGVETPEQRDYLAARGVDYLQGYLIGRPMPLESLLSSLTVQEQQ 5mf5 A 1.77 BS02 MG A 1 V40 N98 V36 N94 A0A140SMD7 ASPSSELRRALEANEFIPYYQPLSPGQGGRWIGVEVLMRWRHPREGLIRPDLFIPFAERSGLIVPMTRALMRQVAEDLGGHAGKLEPGFHIGFNISATHCHELALVDDCRELLAAFPPGHITLVLELTERELIESSEVTDRLFDELHALGVKIAIDDFGTGHSSLAYLRKFQVDCLKIDQSFVARIGIDTLSGHILDSIVELSAKLDLDIVAEGVETPEQRDYLAARGVDYLQGYLIGRPMPLESLLSSLTVQEQQ 5mgb A 2.80 BS01 CAA A 1 P20 V21 A59 G60 A61 D62 I63 F66 V96 G100 E103 R118 E123 L126 I128 Y156 P25 V26 A64 G65 A66 D67 I68 F71 V101 G105 E108 R123 E128 L131 I133 Y161 4.2.1.17,5.3.3.8,1.1.1.35 P07896 PRGSHMAEYLRLPHSLAMIRLCNPPVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFSAFTPGLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPVEEAIKFAQKIIDKPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQASVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSTFLSQYREVHHIEQRTISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYRQNPDIPQLEPSDYLRRLVAQGSPPLKEWQSLAGPHGS 5mgb B 2.80 BS01 CAA B 1 P20 V21 A59 G60 A61 D62 I63 F66 L75 V96 L98 G100 E103 P122 E123 L126 Y156 K275 K463 P22 V23 A61 G62 A63 D64 I65 F68 L77 V98 L100 G102 E105 P124 E125 L128 Y158 K277 K465 4.2.1.17,5.3.3.8,1.1.1.35 P07896 SHMAEYLRLPHSLAMIRLCNPPVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFSAFTPGLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPVEEAIKFAQKIIDKPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQASVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSTFLSQYREVHHIEQRTISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYRQNPDIPQLEPSDYLRRLVAQGSPPLKEWQSLAGPH 5mn5 A 2.80 BS01 GTP A 1 G20 G21 G22 N25 G104 M105 G107 G108 T109 G110 P135 E139 R143 F183 A186 D187 L190 G8 G9 G10 N13 G81 M82 G84 G85 T86 G87 P112 E116 R120 F160 A163 D164 L167 P0A031 TLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQIGNPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGF 5sz4 A 1.60 BS02 72D A 1 H94 H96 H119 V121 V135 V143 L198 T199 T200 W209 H91 H93 H116 V118 V131 V139 L194 T195 T196 W205 4.2.1.1 P00918 27860128 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5t04 A 3.30 BS01 III B 1 D54 L55 F128 H132 H133 Y146 M208 R213 T226 T231 I238 R327 F331 I334 D336 W339 F344 Y347 D12 L13 F78 H82 H83 Y96 M158 R163 T176 T181 I188 R413 F417 I420 D422 W425 F430 Y433 3.2.1.17 P20789 27924846 TSESDTAGPNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMVNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLNNKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYGSGSPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALAYASSAINPILYNLV 5t04 A 3.30 BS02 TCE A 1 M1106 G1113 F1114 K1135 S1136 R1137 W1138 M323 G330 F331 K352 S353 R354 W355 3.2.1.17 P20789 27924846 TSESDTAGPNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMVNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLNNKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYGSGSPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALAYASSAINPILYNLV 5t14 A 3.00 BS01 NUC C 1 Q59 V60 R63 S196 D198 E199 K321 V354 S355 G356 I357 G358 V360 T361 R454 T469 R470 A471 S472 T473 Q29 V30 R33 S166 D168 E169 K234 V267 S268 G269 I270 G271 V273 T274 R367 T382 R383 A384 S385 T386 2.7.7.7 Q9UBT6 27894903 LDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPN 5t14 A 3.00 BS02 NUC D 1 T44 F49 M133 S134 M135 A151 P153 F155 I156 F171 S388 T390 S391 R413 K414 S415 M416 S417 V418 E419 T421 F465 R507 L508 T14 F19 M103 S104 M105 A121 P123 F125 I126 F141 S301 T303 S304 R326 K327 S328 M329 S330 V331 E332 T334 F378 R420 L421 2.7.7.7 Q9UBT6 27894903 LDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPN 5t14 A 3.00 BS05 DZ4 A 1 D107 M108 D109 A110 F111 Y112 S137 T138 Y141 R144 D198 E199 K328 D77 M78 D79 A80 F81 Y82 S107 T108 Y111 R114 D168 E169 K241 2.7.7.7 Q9UBT6 27894903 LDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPN 5t14 B 3.00 BS01 NUC P 1 V60 R63 S196 E199 K321 S355 G356 I357 G358 K359 V360 T361 R454 K468 T469 R470 A471 S472 T473 V30 R33 S166 E169 K234 S268 G269 I270 G271 K272 V273 T274 R367 K381 T382 R383 A384 S385 T386 2.7.7.7 Q9UBT6 27894903 LDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPN 5t14 B 3.00 BS05 DZ4 B 1 D107 M108 D109 A110 F111 Y112 S137 T138 Y141 R144 A151 D198 K328 D77 M78 D79 A80 F81 Y82 S107 T108 Y111 R114 A121 D168 K241 2.7.7.7 Q9UBT6 27894903 LDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPN 5t6m B 1.80 BS01 78U B 1 K82 E104 T105 G106 A107 Q109 H110 L161 V187 G228 G298 Y301 K82 E104 T105 G106 A107 Q109 H110 L161 V187 G228 G298 Y301 4.2.1.20 Q8U093 MWFGEFGGQYVPETLIEPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKIYLKREDLVHGGAHKTNNAIGQALLAKFMGKTRLIAETGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVFHGMLSYFLQDEEGQIKPTHSIAPGLDYPGVGPEHAYLKKIQRAEYVTVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKVSG 5t6m C 1.80 BS01 78U C 1 K82 E104 T105 G106 A107 Q109 H110 L161 S185 V187 G298 Y301 K82 E104 T105 G106 A107 Q109 H110 L161 S185 V187 G298 Y301 4.2.1.20 Q8U093 MWFGEFGGQYVPETLIEPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKIYLKREDLVHGGAHKTNNAIGQALLAKFMGKTRLIAETGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVFHGMLSYFLQDEEGQIKPTHSIAPGLDYPGVGPEHAYLKKIQRAEYVTVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKVSGNVLEH 5t6m D 1.80 BS01 78U D 1 E104 L169 Y181 I183 V187 P189 H275 Y301 E104 L169 Y181 I183 V187 P189 H275 Y298 4.2.1.20 Q8U093 MWFGEFGGQYVPETLIEPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKIYLKREDLVHGGAHKTNNAIGQALLAKFMGKTRLIAETGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVFHGMLSYFLQDQIKPTHSIAPGLDYPGVGPEHAYLKKIQRAEYVTVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKVS 5tct A 2.90 BS01 NUC W 1 K331 D455 K66 D190 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct A 2.90 BS02 NUC K 1 K334 T335 R456 F459 K511 K512 K69 T70 R191 F194 K246 K247 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct A 2.90 BS03 ADP A 1 D429 S430 G431 K432 T433 T434 E473 D474 R548 K550 L553 K554 L557 D164 S165 G166 K167 T168 T169 E208 D209 R283 K285 L288 K289 L292 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct B 2.90 BS01 NUC W 1 K331 H513 K66 H248 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct B 2.90 BS02 NUC K 1 T335 Q338 D455 R456 F459 T70 Q73 D190 R191 F194 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct B 2.90 BS04 ADP B 1 W393 L397 I428 D429 S430 G431 K432 T433 T434 P549 K550 L553 L557 W128 L132 I163 D164 S165 G166 K167 T168 T169 P284 K285 L288 L292 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct E 2.90 BS01 NUC W 1 T335 R456 T70 R191 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct E 2.90 BS02 ADP E 1 W393 D429 S430 G431 K432 T433 T434 E473 D474 R548 P549 K550 L553 K554 L557 W128 D164 S165 G166 K167 T168 T169 E208 D209 R283 P284 K285 L288 K289 L292 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct F 2.90 BS01 NUC W 1 D455 R456 D190 R191 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct F 2.90 BS02 NUC K 1 K331 N332 T335 K512 H513 K66 N67 T70 K247 H248 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct C 2.90 BS01 NUC W 1 N332 K512 H513 N67 K247 H248 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct C 2.90 BS02 ADP C 1 D429 S430 G431 K432 T433 T434 E473 D474 R548 P549 K550 L553 L557 D164 S165 G166 K167 T168 T169 E208 D209 R283 P284 K285 L288 L292 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tct D 2.90 BS01 NUC W 1 N332 F459 K512 N67 F194 K247 3.6.4.- P03070 27921994 KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD 5tgq A 1.88 BS01 CA A 1 D76 D93 F94 D76 D93 F94 27913730 MNFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFMDREEEIWIDFKAFKITNMDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQMQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEIMLKDLEDKLKNSNDNSI 5tgx A 2.30 BS01 NUC H 1 R35 T71 K72 N73 D76 K95 A96 F97 K98 N101 D103 S104 N105 P106 D107 G109 T110 N112 K113 K166 P167 Q168 Q170 R34 T70 K71 N72 D75 K93 A94 F95 K96 N99 D100 S101 N102 P103 D104 G106 T107 N109 K110 K163 P164 Q165 Q166 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5tgx A 2.30 BS02 NUC I 1 R35 E69 K70 T71 K72 R162 I163 N164 K166 Q170 R199 R34 E68 K69 T70 K71 R159 I160 N161 K163 Q166 R195 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5tgx A 2.30 BS03 CA A 1 D76 D93 F94 K95 D75 D91 F92 K93 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5tgx B 2.30 BS01 NUC H 1 R35 K70 T71 K72 R162 I163 N164 P165 K166 Q170 R199 R34 K69 T70 K71 R159 I160 N161 P162 K163 Q166 R195 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 A 2.33 BS01 NUC H 1 T71 K72 N73 G109 T110 N112 K113 K166 P167 Q168 T70 K71 N72 G106 T107 N109 K110 K163 P164 Q165 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 A 2.33 BS02 NUC h 1 R35 A38 S41 D76 K95 A96 F97 K98 N101 D103 S104 N105 P106 D107 K166 Q170 R34 A37 S40 D75 K93 A94 F95 K96 N99 D100 S101 N102 P103 D104 K163 Q166 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 A 2.33 BS03 NUC I 1 R35 N105 R162 N164 P165 K166 Q170 R199 K207 R34 N102 R159 N161 P162 K163 Q166 R195 K203 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 A 2.33 BS04 NUC i 1 R35 K70 T71 K72 R34 K69 T70 K71 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 A 2.33 BS06 MG A 2 D76 D93 D75 D91 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 B 2.33 BS01 NUC H 1 R35 R162 I163 N164 P165 K166 Q170 R199 R34 R159 I160 N161 P162 K163 Q166 R195 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 B 2.33 BS03 NUC I 1 T71 K72 N73 G109 T110 N112 K113 K166 Q168 T70 K71 N72 G106 T107 N109 K110 K163 Q165 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 B 2.33 BS04 NUC i 1 R35 S41 D76 K95 A96 F97 K98 N101 D103 S104 N105 P106 D107 K166 Q170 R34 S40 D75 K93 A94 F95 K96 N99 D100 S101 N102 P103 D104 K163 Q166 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 C 2.33 BS02 NUC j 1 R35 A38 D76 K95 A96 F97 K98 N101 D103 S104 N105 P106 D107 K166 Q170 K206 R34 A37 D75 K93 A94 F95 K96 N99 D100 S101 N102 P103 D104 K163 Q166 K202 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5th3 C 2.33 BS03 NUC K 1 R35 N105 R162 I163 N164 P165 K166 Q170 R199 R34 N102 R159 I160 N161 P162 K163 Q166 R195 27913730 NFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCKFKFDREEEIWIDFKAFKITNDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNESFRINPKPQQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEILKDLEDKLKNSNDNSI 5ths A 1.90 BS02 B3N A 1 D101 H142 H143 F152 D178 H180 F208 D267 Y306 D88 H129 H130 F139 D165 H167 F195 D254 Y293 3.5.1.98 Q9BY41 LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILAGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 5ths B 1.90 BS02 B3N B 1 H142 H143 F152 D178 H180 F208 D267 G304 Y306 H122 H123 F132 D158 H160 F188 D247 G284 Y286 3.5.1.98 Q9BY41 LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDHPDSIEYGLATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILAGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 5tht C 2.41 BS01 B3N C 1 K33 D101 H142 H143 G151 F152 D178 H180 F208 D267 P273 M274 Y306 K20 D77 H118 H119 G127 F128 D154 H156 F184 D243 P249 M250 Y282 3.5.1.98 Q9BY41 LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEEYGLDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGAGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 5tht D 2.41 BS01 B3N D 1 H142 H143 G151 F152 D178 H180 F208 D267 P273 M274 Y306 H112 H113 G121 F122 D148 H150 F178 D237 P243 M244 Y276 3.5.1.98 Q9BY41 LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGAGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 5thu A 1.95 BS01 ZN A 1 D178 H180 D267 A304 D158 H160 D247 A284 3.5.1.98 Q9BY41 LVPVYIYSPEYVSMCDSKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGAGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVVI 5thu A 1.95 BS02 B3N A 1 H142 H143 G151 D178 H180 F208 D267 A304 Y306 H122 H123 G131 D158 H160 F188 D247 A284 Y286 3.5.1.98 Q9BY41 LVPVYIYSPEYVSMCDSKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGAGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVVI 5thu B 1.95 BS02 B3N B 1 H142 H143 F152 D178 H180 F208 D267 A304 Y306 H109 H110 F119 D145 H147 F175 D234 A271 Y273 3.5.1.98 Q9BY41 LVPVYIYSPEYVSMCDSPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEYGLTEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGAGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 5thu B 1.95 BS03 GGG B 1 E335 F336 T338 A339 E302 F303 T305 A306 3.5.1.98 Q9BY41 LVPVYIYSPEYVSMCDSPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEYGLTEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGAGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 5thv B 1.87 BS02 B3N B 1 H142 H143 G151 F152 D178 H180 F208 D267 G304 Y306 H112 H113 G121 F122 D148 H150 F178 D237 G274 Y276 3.5.1.98 Q9BY41 VPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEYGLTEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGAYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 5tjx A 1.41 BS01 GBT A 1 H434 S478 E479 G480 D483 Y555 I557 M561 D572 A573 C574 K575 S578 T596 S597 W598 G599 G601 C602 H44 S88 E89 G90 D93 Y160 I162 M166 D177 A178 C179 K180 S183 T201 S202 W203 G204 G206 C207 3.4.21.34 P03952 IVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 5to8 A 1.98 BS01 7FM A 1 L431 G432 E433 V487 M502 E503 L504 Y505 G508 E509 R553 L556 D567 L12 G13 E14 V66 M79 E80 L81 Y82 G85 E86 R128 L131 D142 2.7.10.2 Q14289 27876318 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTNKEKFMSEAVIMKNLDHPHIVKLIGIIEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESCVHRDIAVRNILVASPECVKLGDFGLSRIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAM 5ttf A 1.72 BS06 7KZ A 1 D1078 D1083 L1086 D1088 C1098 R1157 F1158 K1162 D161 D166 L169 D171 C177 R236 F237 K241 2.1.1.-,2.1.1.43 Q96KQ7 TEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQ 5ttf B 1.72 BS06 7KZ B 1 A1077 D1078 R1080 D1083 L1086 D1088 C1098 R1157 F1158 I1161 K1162 A160 D161 R163 D166 L169 D171 C178 R237 F238 I241 K242 2.1.1.-,2.1.1.43 Q96KQ7 TEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSR 5txe A 2.20 BS01 III C 1 S53 W111 I113 S115 W116 N121 A122 S124 A126 H214 L216 Y438 P482 A527 T557 N562 L570 Y573 H638 S19 W77 I79 S81 W82 N87 A88 S90 A92 H180 L182 Y404 P448 A493 T523 N528 L536 Y539 H604 E8RUP5 APPVTPEVLVRLADIGTMSASETTPLLSLSPDGRYVAFQVRQADPVTNLNVFRMVVKATDGATDAIDVDVGGEYLFWTIPSWGYARNAPSGANLTIQPRWSPSGTHLAYLRQDQGRVRVWRASVKGEGASPVIEDAYDIEDVQWLDDNTLIYSGRPGFVEAEAEIEREGRRGWVYDERFHPLTGARPRVLEPISIVYQVLDLKTGTRRAATPTEVARLREKPDPLRAMVGRTTFSVSRTDPQNINAPTTLVARRGEGEPVRCDEEACQNITRMWGDETANVLYFLRREGWASNEMALYRMPADALKPVRIWHATGLLQGCERQAKRLICAQESALQPRRLVTLNLTSGQMSPLYDPNPDLSRYRLPKVERLTLRNRNGIEVFSDLVLPPDYQLGTRLPLVIVQYSSRGFLRGGTGDENPILPLATAGFAVLSFHSPRSEASYQRFTSPIAQSKAEYSNWRNRWNILHTLEDLIDDLDRRGVIDPARVGLTGLADGATTVHFGLINSHRFAAAVTSSCCTDSFTASVMNGPRISGALKAYGIETDQADDGPFWAATSFVVNASRLDTPLLIQSADEEYLGALPGFTALQQARKPVELIIYPNEHHVKWQPAHRLAVYNRTIDWFRFWLMDQSDPAPDKAAQYDRWRALRALRQ 5u1p A 1.90 BS01 NAP A 1 S10 R11 G12 L13 R33 L51 D52 I53 T54 V77 S78 G79 V80 T102 V128 S129 S130 Y146 K150 P174 G175 W176 V177 T179 D180 M181 S10 R11 G12 L13 R33 L51 D52 I53 T54 V77 S78 G79 V80 T102 V128 S129 S130 Y146 K150 P174 G175 W176 V177 T179 D180 M181 1.1.1.184 A0A0H3KHT8 MKTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIAALGWKLDGERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIASLQTRHAACISLHPGWVRTDMGGAQAALDPATSVTGMRRVIAEAGADVSQSNGRFFQYDGVELSW 5u25 A 2.30 BS01 FAD A 1 L123 G124 G126 P127 G128 V146 E147 R148 Y149 G154 V155 C156 G160 C161 K165 G226 D227 G228 Y246 A266 A267 G268 S286 I307 G434 D435 M441 L442 A443 H444 A446 Y474 L10 G11 G13 P14 G15 V33 E34 R35 Y36 G41 V42 C43 G47 C48 K52 G113 D114 G115 Y133 A153 A154 G155 S173 I194 G321 D322 M328 L329 A330 H331 A333 Y361 1.8.1.4 A0A1D3G1L2 ADAEYDVVVLGGGPGGYSAAFAAADEGLKVAIVERYKTLGGVCLNVGCIPSKALLHNAAVIDEVRHLAANGIKYPEPELDIDMLRAYKDGVVSRLTGGLAGMAKSRKVDVIQGDGQFLDPHHLEVSLTAGDAYEQAAPTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALALKEVPGKLLIIGGGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGANAPKEPQRYDAVLVAAGRAPNGKLISAEKAGVAVTDRGFIEVDKQMRTNVPHIYAIGDIVGQPMLAHKAVHEGHVAAENCAGHKAYFDARVIPGVAYTSPEVAWVGETELSAKASGRKITKANFPWAASGRAIANGCDNGFTKLIFDAETGRIIGGGIVGPNGGDMIGEVCLAIEMGCDAADIGKTIHPHPTLGESIGMAAEVALGVCTDLPPQ 5u26 A 1.85 BS01 MMV A 1 I5 W6 I20 D27 Q28 F31 R32 L50 P51 L57 R60 I94 Y100 I12 W13 I27 D34 Q35 F38 R39 L57 P58 L64 R67 I101 Y107 1.5.1.3 A0A0E8UVJ4 LVPRGSHMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS 5u26 A 1.85 BS02 NAP A 1 W6 A7 I14 G15 R16 G18 D19 I20 G43 R44 R45 T46 S49 L65 S66 R67 Q68 G80 I94 G95 G96 G97 Q98 V99 Y100 L102 A126 W13 A14 I21 G22 R23 G25 D26 I27 G50 R51 R52 T53 S56 L72 S73 R74 Q75 G87 I101 G102 G103 G104 Q105 V106 Y107 L109 A133 1.5.1.3 A0A0E8UVJ4 LVPRGSHMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS 5u27 A 2.05 BS02 P65 A 1 I5 W6 A7 D19 I20 R23 D27 Q28 F31 L50 P51 I94 Y100 I12 W13 A14 D26 I27 R30 D34 Q35 F38 L57 P58 I101 Y107 1.5.1.3 A0A0E8UVJ4 LVPRGSHMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS 5u4x A 1.88 BS02 7VM A 1 Y150 F153 Y154 M163 E258 M260 Y262 N266 E267 H415 W416 Q447 K471 P473 F475 Y4 F7 Y8 M17 E112 M114 Y116 N120 E121 H269 W270 Q301 K325 P327 F329 2.1.1.319 Q86X55 AVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRY 5u63 A 1.99 BS01 FAD A 1 G13 S14 G15 P16 A17 T36 G37 L38 Q39 G42 Q43 L44 T47 I50 N52 H84 I85 A112 T113 G114 A115 E160 H245 G285 D286 R293 Q294 A295 S298 G11 S12 G13 P14 A15 T34 G35 L36 Q37 G40 Q41 L42 T45 I48 N50 H82 I83 A110 T111 G112 A113 E158 H243 G283 D284 R291 Q292 A293 S296 1.8.1.9 P43788 DIKHAKLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTDEIENWPGDFEMTTGSGLMQRMLQHAEKFETEIVFDHINRVDLSSRPFKLFGDVQNFTCDALIIATGASARYIGLPSEENYKGRGVSACATCDGFFYRNKPVGVIGGGNTAVEEALYLANIASTVHLIHRRDSFRAEKILIDRLYKKVEEGKIVLHTDRTLDEVLGDNMGVTGLRLANTKTGEKEELKLDGLFVAIGHSPNTEIFQGQLELNNGYIVVKSGLDGNATATSVEGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDAQE 5u63 A 1.99 BS02 NAP A 1 R118 G154 G155 H176 R177 R178 R182 I243 G244 H245 R116 G152 G153 H174 R175 R176 R180 I241 G242 H243 1.8.1.9 P43788 DIKHAKLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTDEIENWPGDFEMTTGSGLMQRMLQHAEKFETEIVFDHINRVDLSSRPFKLFGDVQNFTCDALIIATGASARYIGLPSEENYKGRGVSACATCDGFFYRNKPVGVIGGGNTAVEEALYLANIASTVHLIHRRDSFRAEKILIDRLYKKVEEGKIVLHTDRTLDEVLGDNMGVTGLRLANTKTGEKEELKLDGLFVAIGHSPNTEIFQGQLELNNGYIVVKSGLDGNATATSVEGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDAQE 5u63 B 1.99 BS02 NAP B 1 R118 G154 G155 H176 R177 R178 I243 G244 H245 R293 R121 G157 G158 H179 R180 R181 I246 G247 H248 R296 1.8.1.9 P43788 SNAMSDIKHAKLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGGQLTTTDEIENWPGDFEMTTGSGLMQRMLQHAEKFETEIVFDHINRVDLSSRPFKLFGDVQNFTCDALIIATGASARYIGLPSEENYKGRGVSACATCDGFFYRNKPVGVIGGGNTAVEEALYLANIASTVHLIHRRDSFRAEKILIDRLYKKVEEGKIVLHTDRTLDEVLGDNMGVTGLRLANTKTGEKEELKLDGLFVAIGHSPNTEIFQGQLELNNGYIVVKSGLDGNATATSVEGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDAQ 5u71 A 3.87 BS01 III R 1 E543 T844 R975 E1046 S1049 K1165 E503 T606 R712 E783 S786 K902 3.6.3.49 P13569 PLEKASVVSKLFFSWTRPILRKGYRQRLELSDIYQIPSVDSADNLSEKLEREWDRELASKKNPKLINALRRCFFWRFMFYGIFLYLGEVTKAVQPLLLGRIIASYDPDNKEERSIAIYLGIGLCLLFIVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQLVSLLSNNLNKFDEGLALAHFVWIAPLQVALLMGLIWELLQASAFCGLGFLIVLALFQAGLGRMMMKYRDQRAGKISERLVITSEMIENIQSVKAYCWEEAMEKMIENLRQTELKLTRKAAYVRYFNSSAFFFSGFFVVFLSVLPYALIKGIILRKIFTTISFCIVLRMAVTRQFPWAVQTWYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVVMENVTAFWEPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSKLMTTWNTYLRYITVHKSLIFVLIWCLVIFLAEVAASLVVLWLSTSSYYVFYIYVGVADTLLAMGFFRGLPLVHTLITVSKILHHKMLHSVLQAPMSTLNTLKAGGILNRFSKDIAILDDLLPLTIFDFIQLLLIVIGAIAVVAVLQPYIFVATVPVIVAFIMLRAYFLQTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGEGEGRVGIILTLAMNIMSTLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEGGQMTVKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSGTFRKNLDPYEQWSDQEIWKVADEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLLNERSL 5wsi A 1.49 BS01 EOH A 1 W78 Y185 W331 W78 Y185 W330 Q7YS85 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLNTLKNRNPKLKTLLSVGGWNFGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGWRDKRHLTTLVKEMKAEFVREAQAGTEQLLLSAAVPAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSPLFRGQEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGKSYTLASSKTDVGAPISGPGIPGQFTKEKGILAYYEICDFLHGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLAFPLTNAIKDVLAGV