4zfi A 2.00 BS01 4NJ A 1 L54 F55 G58 I61 Y67 F91 V93 H96 I99 Y100 L37 F38 G41 I44 Y50 F74 V76 H79 I82 Y83 6.3.2.- Q00987 27709883 QIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQ 4zfi C 2.00 BS01 4NJ C 1 L54 F55 G58 I61 Y67 H96 I99 Y100 L37 F38 G41 I44 Y50 H79 I82 Y83 6.3.2.- Q00987 27709883 QIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVV 4zfi D 2.00 BS01 4NJ D 1 L54 F55 G58 I61 Y67 V93 H96 I99 Y100 L36 F37 G40 I43 Y49 V75 H78 I81 Y82 6.3.2.- Q00987 27709883 IPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVN 5a6l A 1.80 BS01 XYP A 1 W23 E142 W26 E145 3.2.1.8 A3DJS9 MASATINLSAEKQVIRGFGGMNHPVWISDLTPQQRDTAFGNGEGQLGFTILRIHVDENRNNWSKEVATARRAIELGAIVSASPWNPPSNMVETFTRNGVPNQKRLRYDKYGDYVQHLNDFVAYMKSNGVDLYAISVQNEPDYAHEWTWWTPQEMLRFMRDYAGQINCRVMAPESFQYLKNMSDPILNDPQALANLDILGAHFYGTTVNNMPYPLFEQKGAGKELWMTAVYVPNSDSNSADRWPEALEVAHNMHNALVEGNFQAYVWWYIRRSYGPMKEDGTISKRGYMMAHYSKFVRPGYVRVDATKNPTYNVYLSACKNKKDNSVVAVVINKSTEAKTINISVPGTSIRKWERYVTTGSKNLRKESDINASGTTFQVTLEPQSVTTFV 5a6l A 1.80 BS02 XYP A 2 W23 E142 W143 W26 E145 W146 3.2.1.8 A3DJS9 MASATINLSAEKQVIRGFGGMNHPVWISDLTPQQRDTAFGNGEGQLGFTILRIHVDENRNNWSKEVATARRAIELGAIVSASPWNPPSNMVETFTRNGVPNQKRLRYDKYGDYVQHLNDFVAYMKSNGVDLYAISVQNEPDYAHEWTWWTPQEMLRFMRDYAGQINCRVMAPESFQYLKNMSDPILNDPQALANLDILGAHFYGTTVNNMPYPLFEQKGAGKELWMTAVYVPNSDSNSADRWPEALEVAHNMHNALVEGNFQAYVWWYIRRSYGPMKEDGTISKRGYMMAHYSKFVRPGYVRVDATKNPTYNVYLSACKNKKDNSVVAVVINKSTEAKTINISVPGTSIRKWERYVTTGSKNLRKESDINASGTTFQVTLEPQSVTTFV 5a6l A 1.80 BS04 XYP A 4 F172 Q173 Y200 G201 F175 Q176 Y203 G204 3.2.1.8 A3DJS9 MASATINLSAEKQVIRGFGGMNHPVWISDLTPQQRDTAFGNGEGQLGFTILRIHVDENRNNWSKEVATARRAIELGAIVSASPWNPPSNMVETFTRNGVPNQKRLRYDKYGDYVQHLNDFVAYMKSNGVDLYAISVQNEPDYAHEWTWWTPQEMLRFMRDYAGQINCRVMAPESFQYLKNMSDPILNDPQALANLDILGAHFYGTTVNNMPYPLFEQKGAGKELWMTAVYVPNSDSNSADRWPEALEVAHNMHNALVEGNFQAYVWWYIRRSYGPMKEDGTISKRGYMMAHYSKFVRPGYVRVDATKNPTYNVYLSACKNKKDNSVVAVVINKSTEAKTINISVPGTSIRKWERYVTTGSKNLRKESDINASGTTFQVTLEPQSVTTFV 5a6m A 1.17 BS03 XYS A 1 W81 N135 E136 W143 Y200 W264 W84 N138 E139 W146 Y203 W267 3.2.1.8 A3DJS9 MASATINLSAEKQVIRGFGGMNHPVWISDLTPQQRDTAFGNGEGQLGFTILRIHVDENRNNWSKEVATARRAIELGAIVSASPWNPPSNMVETFTRNGVPNQKRLRYDKYGDYVQHLNDFVAYMKSNGVDLYAISVQNEPDYAHEWTWWTPQEMLRFMRDYAGQINCRVMAPESFQYLKNMSDPILNDPQALANLDILGAHFYGTTVNNMPYPLFEQKGAGKELWMTAVYVPNSDSNSADRWPEALEVAHNMHNALVEGNFQAYVWWYIRRSYGPMKEDGTISKRGYMMAHYSKFVRPGYVRVDATKNPTYNVYLSACKNKKDNSVVAVVINKSTEAKTINISVPGTSIRKWERYVTTGSKNLRKESDINASGTTFQVTLEPQSVTTFV 5azi A 2.45 BS01 4NP A 1 T11 T12 G277 T13 T14 G279 2.7.1.30 D3KVM3 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 5azj A 2.61 BS01 4NP A 1 T11 T12 T13 T14 2.7.1.30 D3KVM3 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 5b6q A 1.78 BS01 HEM A 1 V6 C11 C14 H15 A20 A22 P23 W31 R34 Q37 L42 V46 K50 A52 M53 P54 G57 M58 A70 I71 M74 V6 C11 C14 H15 A20 A22 P23 W31 R34 Q37 L42 V46 K50 A52 M53 P54 G57 M58 A70 I71 M74 Q9RHJ6 27648635 QEGKAVYDKACHICHSMGVAGAPKAHDAAAWEPRIAQGLDTLVSTVKTGKGAMPPGGMCTDCTDEDYKSAIEYMSK 5b6q B 1.78 BS01 HEM B 1 C11 I13 C14 H15 A20 A22 P23 W31 R34 V46 M53 P54 G57 M58 I71 M74 C11 I13 C14 H15 A20 A22 P23 W31 R34 V46 M53 P54 G57 M58 I71 M74 Q9RHJ6 27648635 QEGKAVYDKACHICHSMGVAGAPKAHDAAAWEPRIAQGLDTLVSTVKTGKGAMPPGGMCTDCTDEDYKSAIEYMSK 5c9l A 1.65 BS01 CA A 1 D132 R134 H203 D116 R118 H187 Q7N8J0 IENSAIALSGIVSVANNADNRLEVFGVSTDSAVWHNWQTAPLPNSSWAGWNKFNGVVTSKPAVHRNSDGRLEVFVRGTDNALWHNWQTAADTNTWSSWQPLYGGITSNPEVCLNSDGRLEVFVRGSDNALWHIWQTAAHTNSWSNWKSLGGTLTSNPAAHLNADGRIEVFARGADNALWHIWQTAAHTDQWSNWQSLKSVITSDPVVINNCDGRLEVFARGADSTLRHISQIGSDSVSWSNWQCLDGVITSAPAAVKNISGQLEVFARGADNTLWRTWQTSHNGPWSNWSSFTGIIASAPTVAKNSDGRIEVFVLGLDKALWHLWQTTSSTTSSWTTWALIGGITLIDASVIK 5c9p A 1.75 BS01 FUC A 1 G119 G120 G141 S142 W147 W162 G103 G104 G125 S126 W131 W146 Q7N8J0 IENSAIALSGIVSVANNADNRLEVFGVSTDSAVWHNWQTAPLPNSSWAGWNKFNGVVTSKPAVHRNSDGRLEVFVRGTDNALWHNWQTAADTNTWSSWQPLYGGITSNPEVCLNSDGRLEVFVRGSDNALWHIWQTAAHTNSWSNWKSLGGTLTSNPAAHLNADGRIEVFARGADNALWHIWQTAAHTDQWSNWQSLKSVITSDPVVINNCDGRLEVFARGADSTLRHISQIGSDSVSWSNWQCLDGVITSAPAAVKNISGQLEVFARGADNTLWRTWQTSHNGPWSNWSSFTGIIASAPTVAKNSDGRIEVFVLGLDKALWHLWQTTSSTTSSWTTWALIGGITLIDASVILE 5c9p A 1.75 BS02 FUC A 2 G71 V72 G93 T94 W99 W114 G55 V56 G77 T78 W83 W98 Q7N8J0 IENSAIALSGIVSVANNADNRLEVFGVSTDSAVWHNWQTAPLPNSSWAGWNKFNGVVTSKPAVHRNSDGRLEVFVRGTDNALWHNWQTAADTNTWSSWQPLYGGITSNPEVCLNSDGRLEVFVRGSDNALWHIWQTAAHTNSWSNWKSLGGTLTSNPAAHLNADGRIEVFARGADNALWHIWQTAAHTDQWSNWQSLKSVITSDPVVINNCDGRLEVFARGADSTLRHISQIGSDSVSWSNWQCLDGVITSAPAAVKNISGQLEVFARGADNTLWRTWQTSHNGPWSNWSSFTGIIASAPTVAKNSDGRIEVFVLGLDKALWHLWQTTSSTTSSWTTWALIGGITLIDASVILE 5c9p A 1.75 BS03 FUC A 3 I311 I312 G332 L333 W338 I295 I296 G316 L317 W322 Q7N8J0 IENSAIALSGIVSVANNADNRLEVFGVSTDSAVWHNWQTAPLPNSSWAGWNKFNGVVTSKPAVHRNSDGRLEVFVRGTDNALWHNWQTAADTNTWSSWQPLYGGITSNPEVCLNSDGRLEVFVRGSDNALWHIWQTAAHTNSWSNWKSLGGTLTSNPAAHLNADGRIEVFARGADNALWHIWQTAAHTDQWSNWQSLKSVITSDPVVINNCDGRLEVFARGADSTLRHISQIGSDSVSWSNWQCLDGVITSAPAAVKNISGQLEVFARGADNTLWRTWQTSHNGPWSNWSSFTGIIASAPTVAKNSDGRIEVFVLGLDKALWHLWQTTSSTTSSWTTWALIGGITLIDASVILE 5drz L 2.54 BS01 III P 1 N28 K30 W50 M53 N33 K35 W55 M58 FLLTQSPDSLAVTLGETATITCRSSRNILHSLNNKNYLAWYQQRPGQAPKLLVIWASMRVSGVADRFSGSGSGTDFALTISSLQPEDAAVYYCQHYYTTHRTFGQGTRVEIRRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 5drz L 2.54 BS02 MG L 1 P80 A83 I106 D167 S171 P85 A88 I111 D172 S176 FLLTQSPDSLAVTLGETATITCRSSRNILHSLNNKNYLAWYQQRPGQAPKLLVIWASMRVSGVADRFSGSGSGTDFALTISSLQPEDAAVYYCQHYYTTHRTFGQGTRVEIRRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 5drz H 2.54 BS01 III P 1 D31 Y32 Y33 K52A D95 D96 G97 Y98 Y99 D100 R100A Y100D V100G D31 Y32 Y33 K53 D99 D100 G101 Y102 Y103 D104 R105 Y108 V111 QVQLVQSGGGVVKPGASSRLSCAASGFTFTDYYMSWIRQAPGKGLEWVAYITKDGSEKKYADSLQHRFAVSRDNANNLVFLQLNTVEDDDTGVYYCARDDGYYDRSGYYGVFDLWGQGIRVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS 5e5i B 1.70 BS01 5NJ A 1 S315 T316 S296 T297 2.6.1.13 S8EY38 TNIEAYRDGLKLKTEEDFFACDRQYVCQNYAPVPVVISKGKGARVWDINGNEYYDFLAGVSSLSQGHCHPRVIAALCRQAERLTLTLRAFGNDVTGPACRFMAEMFGYDRVLLMNTGAEAGESALKIARKWAYEVKEIPPDSAKVILCNNNYWGRTITACSSSTTFDCYNNFGPFTPGFELIDYDDVGALEEALKDPNVAAFFVEPIQGEGGVNVPKPGYLKRAHELCRSKNVLLIVDEIQTGLCRTGRLLAADHDEVHPDILLLGKSLSAGVVPISAVMGRADVMDVLKPGTHGSTFGGNPLACAVAVEALTVLKDEKLADRAERLGAQFRDCLRRELYGKVPWIKEIRGRGLLNAVEVDSDAIDPNDVVMKLKENGILSKPTRGRVMRFIPPLVITDEEHRDATTRIIKSFLAVEEERK 5e6i A 4.00 BS01 III E 1 N97 G99 N95 G97 K7N5M3 QLNQSPQSMFIQEGEDVSMNCTSSSIFNTWLWYKQEPGEGPVLLIALYKAGELTSNGRLTAQFGITRKDSFLNISASIPSDVGIYFCAGPGGSSNTGKLIFGQGTTLQVKPDIQNPDPAVYQLRDSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFF 5e6i B 4.00 BS01 III E 1 E30 M50 N51 I96 Y97 E29 M49 N50 I95 Y96 AQVTQNPRYLITVTGKELTVTCSQNMNHEYMSWYRQDPGLGLRQIYYSMNVEVTDKGDVPEGYKVSRKEKRNFPLILESPSPNQTSLYFCASSLIYPGELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 5e6i C 4.00 BS01 III E 1 Y7 E63 K66 A69 T73 D77 L81 R97 Y99 H114 Y116 K146 W147 V152 Q155 L156 Y159 W167 Y171 Y6 E62 K65 A68 T72 D76 L80 R96 Y98 H113 Y115 K145 W146 V151 Q154 L155 Y158 W166 Y170 P01892 SHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWDTELVETRPAGDGTFQKWAAVVVPSTCHVQHEGLPKPLTLRW 5e6i L 4.00 BS01 III O 1 M50 N51 I96 Y97 M50 N51 I96 Y97 EAQVTQNPRYLITVTGKELTVTCSQNMNHEYMSWYRQDPGLGLRQIYYSMNVEVTDKGDVPEGYKVSRKEKRNFPLILESPSPNQTSLYFCASSLIYPGELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 5e6i M 4.00 BS01 III O 1 Y7 E63 K66 T73 D77 Y99 H114 Y116 W147 V152 L156 Y159 W167 Y6 E62 K65 T72 D76 Y98 H113 Y115 W146 V151 L155 Y158 W166 P01892 SHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDEATLRCWALSFYPAEITLTWQRDGEDTQDTELVETRPAGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLR 5e6i P 4.00 BS01 III T 1 N97 T98 N95 T96 K7N5M3 QLNQSPQSMFIQEGEDVSMNCTSSSIFNTWLWYKQEPGEGPVLLIALYKAGELTSNGRLTAQFGITRKDSFLNISASIPSDVGIYFCAGPGGSSNTGKLIFGQGTTLQVKPDIQNPDPAVYQLRDSSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRFKSNSAVAWSNKSDFACANAFNNSIIPEDTFF 5e6i Q 4.00 BS01 III T 1 M50 I96 Y97 M49 I95 Y96 AQVTQNPRYLITVTGKELTVTCSQNMNHEYMSWYRQDPGLGLRQIYYSMNVEVTDKGDVPEGYKVSRKEKRNFPLILESPSPNQTSLYFCASSLIYPGELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQKPVTQIVSAEAWGRAD 5e6i R 4.00 BS01 III T 1 Y7 F9 M45 E63 K66 H70 T73 D77 L81 R97 Y99 Y116 Y123 T143 K146 Q155 L156 Y159 Y7 F9 M43 E61 K64 H68 T71 D75 L79 R95 Y97 Y114 Y121 T141 K144 Q153 L154 Y157 P01892 GSHSMRYFFTSVSRPGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDLRCWALSFYPAEITLTWDTELVETRPAGDGTFQKWAAVVRYTCHVQHEGLPKPLTLR 5e7x A 1.80 BS01 PLM A 1 I47 A69 V76 I83 Q113 S121 V124 L132 S136 S140 L147 I46 A68 V75 I82 Q112 S120 V123 L131 S135 S139 L146 A8HBN5 TKDQRDVNVFKKVLENIGNAVTQFNNDILAYTGGDANHLIHDGDAIIKATENGLQELGPQPPLSLTEALALVGPVQGVNKLIMKTVDHLIEKKGPLVGGGYGPQVKASLQKQAHAAVTLSELVSSKVPSPLAPISKQLSDQVAQALQKGIEAFSI 5e93 A 1.41 BS01 5LL A 1 S44 C45 T46 N67 M69 G70 L71 N73 S99 N127 C130 P131 N132 N194 S195 S45 C46 T47 N68 M70 G71 L72 N74 S100 N128 C131 P132 N133 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 5e93 A 1.41 BS02 FMN A 1 A18 A19 G20 V21 K43 S44 Y58 N67 M69 N127 K164 V193 N194 G221 G222 I225 C248 G249 G250 G271 T272 A19 A20 G21 V22 K44 S45 Y59 N68 M70 N128 K165 V194 N195 G222 G223 I226 C249 G250 G251 G272 T273 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 5ecf B 2.60 BS01 ACD B 1 F11 L15 I18 A69 L72 V76 N80 S121 V124 V128 S136 L139 S140 F5 L9 I12 A63 L66 V70 N74 S115 V118 V122 S130 L133 S134 A8HBN5 DVNVFKKVLENIGNAVTQFNNDILAYTGGDANHLIHDGDAIIKATENGLQELGPQPPLSLTEALALVGPVQGVNKLIMKTVDHLIEKKGPLVGGGYGPQVKASLQKQAHAAVTLSELVSSKVPSPLAPISKQLSDQVAQALQKGIEAFSI 5ecf I 2.60 BS01 ACD I 1 F11 L15 L64 L72 V73 V76 S121 V124 V128 L132 I135 S136 L139 S140 F5 L9 L58 L66 V67 V70 S115 V118 V122 L126 I129 S130 L133 S134 A8HBN5 DVNVFKKVLENIGNAVTQFNNDILAYTGGDANHLIHDGDAIIKATENGLQELGPQPPLSLTEALALVGPVQGVNKLIMKTVDHLIEKKGPLVGGGYGPQVKASLQKQAHAAVTLSELVSSKVPSPLAPISKQLSDQVAQALQKGIEAFS 5ecf I 2.60 BS02 ACD I 2 V22 F25 G44 I47 V79 N80 I83 S109 L110 Q113 V143 L147 V16 F19 G38 I41 V73 N74 I77 S103 L104 Q107 V137 L141 A8HBN5 DVNVFKKVLENIGNAVTQFNNDILAYTGGDANHLIHDGDAIIKATENGLQELGPQPPLSLTEALALVGPVQGVNKLIMKTVDHLIEKKGPLVGGGYGPQVKASLQKQAHAAVTLSELVSSKVPSPLAPISKQLSDQVAQALQKGIEAFS 5ecf J 2.60 BS01 ACD J 1 F11 L72 V73 V76 N80 S121 V124 V128 L139 S140 V143 F3 L60 V61 V64 N68 S100 V103 V107 L118 S119 V122 A8HBN5 NVFKKVLENIGNAVTQFNNDILAYTNHLIHDGDAIIKATENGLQELGPQPPLSLTEALALVGPVQGVNKLIMKTVDHLIEKGPQVKASLQKQAHAAVTLSELVSSKVPSPLAPISKQLSDQVAQALQKGIEAF 5ejd B 2.49 BS01 5PD A 1 H179 W182 G184 T283 A285 K289 T310 V311 N312 L329 Y358 Q390 H391 Q392 N393 I394 H160 W163 G165 T247 A249 K253 T274 V275 N276 L293 Y322 Q354 H355 Q356 N357 I358 F1CWE4 EPFSLSPIKDPQALHKELCSKNVIPVTSTLEDLLPATQAQHVFIKRGTFHSYNWTIKGRSLNMDRLRETCQSLVDRHSILRTSFVEHEGHPIQLVLANLDVKVREVQCWPGEDPMEVCKALWDGKDWPTLNVLGGSLPVRFTLVSCPGNEHVVLTIQISHSQWDGVSIPKLFSDFAAIYNQTPLPPTSDFAHYLYHRVSSAREDVQQDPTFQFWRHYLDGAKMAVPFAQTLWTFKGIVPPTLPSGITMATLVKAATALFLSYHLGSRDVVFGHTVNGRNLPMDNIESLLGCTLNFVPLRVTFPEDSTDWTVMDLLHHTQTQYTRALSHEHVELRDIFQHSTNWPAETPLSLIVQHQNIDLSFSLPLRSLDVQYSKFARFDPLDEVWIFTEPHADRLEVQVCANSRVLGQEQATELANNISAIITKFSTDPTARLLD 5ejd A 2.49 BS01 5PD A 1 H39 S40 I41 H38 S39 I40 F1CWE4 KQLSTDAERELANIWATVLDIPIGTISASDNFFFRGGHSIDAMKASALGRAAGMSFGVADIFDHPVLSELASVAV 5ejd I 2.49 BS01 5PD I 1 H39 S40 H37 S38 F1CWE4 QLSTDAERELANIWATVLDIPIGTISASDNFFFRGGHSIDAMKASALGRAAGMSFGVADIFDHPVLSELASV 5ejl A 2.30 BS01 C2E A 1 R106 R107 R108 R111 D138 I139 S140 G142 G143 C144 A145 K182 S203 C204 Q205 R113 R114 R115 R118 D145 I146 S147 G149 G150 C151 A152 K189 S210 C211 Q212 G3FT00 27650952 SSGLVPRGSHMTEGTIKTSKYEIIAIFREELRKRTEIEIFFNNTSIITQLTRVDFAEFHIQTHRKIPSGHKIRFLLHSDSGKIEFNAALTKHDNDKGIRYAFSLPECLQVVQRRRDPRFRLRHEHDFYCRGRHKNGENYLFDIKDISDGGCALMTKTPNLKFLSHNALLKNAVLMLAEYGEITIDLVVKNVIVITLDNANEESESYYQISCQFKFRHLDDQRRIEKILLDLILEA 5ejl A 2.30 BS02 C2E A 2 L65 H67 G71 K72 Q105 R106 R107 R111 N183 I185 Q201 L75 H77 G81 K82 Q112 R113 R114 R118 N190 I192 Q208 G3FT00 27650952 SSGLVPRGSHMTEGTIKTSKYEIIAIFREELRKRTEIEIFFNNTSIITQLTRVDFAEFHIQTHRKIPSGHKIRFLLHSDSGKIEFNAALTKHDNDKGIRYAFSLPECLQVVQRRRDPRFRLRHEHDFYCRGRHKNGENYLFDIKDISDGGCALMTKTPNLKFLSHNALLKNAVLMLAEYGEITIDLVVKNVIVITLDNANEESESYYQISCQFKFRHLDDQRRIEKILLDLILEA 5eob A 1.75 BS01 5QQ A 1 I1084 V1092 A1108 L1157 P1158 Y1159 M1160 D1164 N1167 R1208 M1211 A1221 D1222 A1226 Y1230 I30 V38 A54 L103 P104 Y105 M106 D110 N113 R154 M157 A167 D168 A172 Y176 2.7.10.1 P08581 27061987 LSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFI 5eu2 A 2.00 BS01 HEM A 1 F28 L31 L41 F42 Y44 H64 K67 V68 V71 Y88 L92 K95 H96 F101 V109 F26 L29 L39 F40 Y42 H62 K65 V66 V69 Y86 L90 K93 H94 F99 V107 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGFRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5eys A 1.75 BS01 HEM A 1 L38 L41 F42 Y44 H64 K67 V68 V71 Y88 L92 K95 H96 V99 V101 W106 V109 L36 L39 F40 Y42 H62 K65 V66 V69 Y86 L90 K93 H94 V97 V99 W104 V107 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSWSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5f0b A 2.15 BS01 HEM A 1 L41 F42 Y44 H64 K67 V68 V71 Y88 L92 K95 H96 V101 W106 V109 M144 L39 F40 Y42 H62 K65 V66 V69 Y86 L90 K93 H94 V99 W104 V107 M142 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSWSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5f5u D 2.75 BS01 III F 1 G55 N57 E58 A59 D60 V62 D63 V66 D100 I101 E104 Y105 F108 G109 K112 F113 G41 N43 E44 A45 D46 V48 D49 V52 D86 I87 E90 Y91 F94 G95 K98 F99 G0S1D3 LDERGSSGPLAPNGLNPATIMEKAVRERIVESYFWKEQCFGVNEADIVDRVVEHVRFVGGVTGVTQKPSPFLCLAFKLLQLAPGDDILKEYLYFGGEKFKYLRALAAFYIRLTRPDKEVYTLLEPFLEDRRKLRRKGKNGTSLTYMDEFIDDLLTKDRVCSTSLWKMRRRDILEDLDLLEPRVSPLGSLEDILEEEEQAAKN 5f5u G 2.75 BS01 III I 1 E58 A59 D60 V62 D63 V66 D100 I101 E104 Y105 F108 K112 F113 E37 A38 D39 V41 D42 V45 D79 I80 E83 Y84 F87 K91 F92 G0S1D3 GPLAPNGLNPATIMEKAVRERIVESYFWKEQCFGVNEADIVDRVVEHVRFVGGVTGVTQKPSPFLCLAFKLLQLAPGDDILKEYLYFGGEKFKYLRALAAFYIRLTRPDKEVYTLLEPFLEDRRKLRRKGKNGTSLTYMDEFIDDLLTKDRVCSTSLWKMRRRDILEDLDLLEPRVSPLGSLEDILEEEEQAAK 5fos A 1.35 BS01 III C 1 M169 W170 I171 N175 P179 E180 R183 L197 K198 I200 A201 Y202 A203 H210 L214 Q217 M62 W63 I64 N68 P72 E73 R76 L90 K91 I93 A94 Y95 A96 H103 L107 Q110 3.6.4.- O74036 27725183 ATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSVMWIDTENTFRPERIREIAQNRGLDPDEVLKHIAYARAFNSNHQMLLVQQAEDMIKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLADLHRLANLYDIAVFVTNQVHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED 5fxq A 2.30 BS01 GD5 A 1 L1005 V1013 A1031 M1079 E1080 M1082 T1083 G1085 M1142 D1153 M1156 L27 V35 A53 M100 E101 M103 T104 G106 M161 D172 M175 2.7.10.1 P08069 SYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENK 5fxr A 2.40 BS01 8LN A 1 L1005 V1013 A1031 K1033 M1079 E1080 M1082 G1085 M1156 L26 V34 A52 K54 M99 E100 M102 G105 M176 2.7.10.1 P08069 GYFSADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSE 5g28 A 1.57 BS01 CL A 1 N98 W99 T102 K235 N97 W98 T101 K234 W8VZW3 27554809 KNIESLFDYSAGQFEFIDHLLTMGVGVHFAALIFFLVVSQFVAPKYRIATALSCIVMVSAGLILNSQAVMWTDAYAYVDGSYQLQDLTFSNGYRYVNWMATIPCLLLQLLIVLNLKGKELFSTATWLILAAWGMIITGYVGQLYEVDDIAQLMIWGAVSTAFFVVMNWIVGTKIFKNRATMLGGTDSTITKVFWLMMFAWTLYPIAYLVPAFMNNADGVVLRQLLFTIADISSKVIYGLMITYIAIQQSAAAGYVPAQQALGRI 5g28 A 1.57 BS02 RET A 1 W99 I103 L106 M135 G139 S160 F164 W201 Y204 P205 Y208 S234 K235 W98 I102 L105 M134 G138 S159 F163 W200 Y203 P204 Y207 S233 K234 W8VZW3 27554809 KNIESLFDYSAGQFEFIDHLLTMGVGVHFAALIFFLVVSQFVAPKYRIATALSCIVMVSAGLILNSQAVMWTDAYAYVDGSYQLQDLTFSNGYRYVNWMATIPCLLLQLLIVLNLKGKELFSTATWLILAAWGMIITGYVGQLYEVDDIAQLMIWGAVSTAFFVVMNWIVGTKIFKNRATMLGGTDSTITKVFWLMMFAWTLYPIAYLVPAFMNNADGVVLRQLLFTIADISSKVIYGLMITYIAIQQSAAAGYVPAQQALGRI 5g2d A 1.80 BS02 CL A 1 N98 W99 N102 K235 N100 W101 N104 K237 W8VZW3 27554809 NSMKNIESLFDYSAGQFEFIDHLLTMGVGVHFAALIFFLVVSQFVAPKYRIATALSCIVMVSAGLILNSQAVMWTDAYAYVDGSYQLQDLTFSNGYRYVNWMANIPCLLLQLLIVLNLKGKELFSTATWLILAAWGMIITGYVGQLYEVDDIAQLMIWGAVSTAFFVVMNWIVGTKIFKNRATMLGGTDSTITKVFWLMMFAWTLYPIAYLVPAFMNNADGVVLRQLLFTIADISSKVIYGLMITYIAIQQSAAAGYVPAQQALGRI 5g4i A 1.50 BS01 PLP A 1 G120 S121 Y147 H148 D251 V253 Q254 K281 G103 S104 Y130 H131 D234 V236 Q237 K264 4.2.3.2 A1RDF1 27709756 DLLARRYATIGPHSPLFYRQPLELVSGSGVWLTDAQGKVYLDGYNNVPHVGHANPAVADAIYQQLLTVNLHTRYLNSRVVEYAEALLSKFDGALERLFLTNSGSEANELALRIARQHTGNTGVLVSDFSYHGNTTSLAEITTGLTVHEPLGAHVRALRIPDVSGIAEVDVPVLLEQSLADVDAAIASLQAAGHGVSVFLFDPLFSTEGLLQLPSGYIEGVATRVRAAGGLVISDEVQSGFGRTGSGMWGYQMFNVEPELVTMGKPMGNGHPIGAVVTTAELLDEFGRHNMFFNTFAGNPVSSAAGLAVLRYMDQEDLMAKADQLGKYIRKRLENIAQRSGNVGSVRGRGLFFGIDIIESDGSRNPAPALTKILIEDMRERGVLISRVGPHDNVLKMRPPLVFGREHADILLGQLELSLASLPQ 5g4j A 1.87 BS01 EXT A 1 Y61 G120 S121 N124 Y147 H148 D251 V253 Q254 K281 K412 R414 Y44 G103 S104 N107 Y130 H131 D234 V236 Q237 K264 K395 R397 4.2.3.2 A1RDF1 27709756 DLLARRYATIGPHSPLFYRQPLELVSGSGVWLTDAQGKVYLDGYNNVPHVGHANPAVADAIYQQLLTVNLHTRYLNSRVVEYAEALLSKFDGALERLFLTNSGSEANELALRIARQHTGNTGVLVSDFSYHGNTTSLAEITTGLTVHEPLGAHVRALRIPDVSGIAEVDVPVLLEQSLADVDAAIASLQAAGHGVSVFLFDPLFSTEGLLQLPSGYIEGVATRVRAAGGLVISDEVQSGFGRTGSGMWGYQMFNVEPELVTMGKPMGNGHPIGAVVTTAELLDEFGRHNMFFNTFAGNPVSSAAGLAVLRYMDQEDLMAKADQLGKYIRKRLENIAQRSGNVGSVRGRGLFFGIDIIESDGSRNPAPALTKILIEDMRERGVLISRVGPHDNVLKMRPPLVFGREHADILLGQLELSLASLPQ 5g4j A 1.87 BS02 EXT B 1 R90 F309 T311 R73 F292 T294 4.2.3.2 A1RDF1 27709756 DLLARRYATIGPHSPLFYRQPLELVSGSGVWLTDAQGKVYLDGYNNVPHVGHANPAVADAIYQQLLTVNLHTRYLNSRVVEYAEALLSKFDGALERLFLTNSGSEANELALRIARQHTGNTGVLVSDFSYHGNTTSLAEITTGLTVHEPLGAHVRALRIPDVSGIAEVDVPVLLEQSLADVDAAIASLQAAGHGVSVFLFDPLFSTEGLLQLPSGYIEGVATRVRAAGGLVISDEVQSGFGRTGSGMWGYQMFNVEPELVTMGKPMGNGHPIGAVVTTAELLDEFGRHNMFFNTFAGNPVSSAAGLAVLRYMDQEDLMAKADQLGKYIRKRLENIAQRSGNVGSVRGRGLFFGIDIIESDGSRNPAPALTKILIEDMRERGVLISRVGPHDNVLKMRPPLVFGREHADILLGQLELSLASLPQ 5g54 A 2.00 BS01 CL A 1 A61 N98 W99 T102 K235 A64 N101 W102 T105 K238 W8VZW3 27554809 PNSMKNIESLFDYSAGQFEFIDHLLTMGVGVHFAALIFFLVVSQFVAPKYRIATALSCIVMVSAGLILNSQAVMWTDAYAYVDGSYQLQDLTFSNGYRYVNWMATIPCLLLQLLIVLNLKGKELFSTATWLILAAWGMIITGYVGQLYEVDDIAQLMIWGAVSTAFFVVMNWIVGTKIFKNRATMLGGTDSTITKVFWLMMFAWTLYPIAYLVPAFMNNADGVVLRQLLFTIADISSKVIYGLMITYIAIQQSAAAGYVPAQQALGRIG 5guh A 2.40 BS01 NUC B 1 Y350 R353 Y355 F370 Y379 Y382 Y383 K386 Y387 E414 I416 Y417 L599 N602 Y603 A604 Y607 K611 T622 Q623 V624 C626 N629 I638 K641 V642 Q645 K649 Y857 N859 C860 Q871 K875 L899 Y216 R219 Y221 F235 Y244 Y247 Y248 K251 Y252 E279 I281 Y282 L464 N467 Y468 A469 Y472 K476 T487 Q488 V489 C491 N494 I503 K506 V507 Q510 K514 Y717 N719 C720 Q731 K735 L759 A8D8P8 27693359 ISILRTRPEAVTSKKGTSGTPLDLLANYFTVETTPKWGLYQYHVDISPEEDSTGVRKALMRVHSKTLGGYLFDGTVLYTVNRLHPDPMELYSDRKTDNERMRILIKLTCEVSPGDYHYIQIFNIIIRKCFNLLKLQLMGRDYFDPEAKIDIPEFKLQIWPGYKTTINQYEDRLLLVTEIAHKVLRMDTVLQMLSEYAATKKIFLEDVVGKIVMTDYNKRTYRVDDVANVSPKSTFKMRDENITYIEYYYKKYNLRIQDPGQPLLISRSKPREIRAGLPELIYLVPELCRQTGLSDEMRANFKLMRSLDVHTKIGPDKRIEKLNNFNRRFTSTPEVVEELATWSLKLSKELVKIKGRQLPPENIIQANNVKYPAGDTTEGWTRDMRSKHLLAIAQLNSWVVITPERQRRDTESFIDLIIKTGGGVGFRMRSPDLVVIRHDGPIEYANMCEEVIARKNPALILCVLARNYADRYEAIKKKCTVDRAVPTQVVCARNMSSKSAMSIATKVAIQINCKLGGSPWTVDIPLPSLMVVGYDVCHDTRSKEKSFGAFVATLDKQMTQYYSIVNAHLSSHMGFNIASAVKKFREKNGTYPARIFIYRDGVGDGQIPYVHSHEVAEIKKKLAEIYAGVEIKLAFIIVSKRINTRIFVQRGRSGENPRPGTVIDDVVTLPERYDFYLVSQNVREGTIAPTSYNVIEDTTGLNPDRIQRLTYKLTHLYFNCSSQVRVPSVCQYAHKLAFLAANSLHNQPHYSLNETLYFL 5guh A 2.40 BS02 MG A 1 Q645 K875 L899 Q510 K735 L759 A8D8P8 27693359 ISILRTRPEAVTSKKGTSGTPLDLLANYFTVETTPKWGLYQYHVDISPEEDSTGVRKALMRVHSKTLGGYLFDGTVLYTVNRLHPDPMELYSDRKTDNERMRILIKLTCEVSPGDYHYIQIFNIIIRKCFNLLKLQLMGRDYFDPEAKIDIPEFKLQIWPGYKTTINQYEDRLLLVTEIAHKVLRMDTVLQMLSEYAATKKIFLEDVVGKIVMTDYNKRTYRVDDVANVSPKSTFKMRDENITYIEYYYKKYNLRIQDPGQPLLISRSKPREIRAGLPELIYLVPELCRQTGLSDEMRANFKLMRSLDVHTKIGPDKRIEKLNNFNRRFTSTPEVVEELATWSLKLSKELVKIKGRQLPPENIIQANNVKYPAGDTTEGWTRDMRSKHLLAIAQLNSWVVITPERQRRDTESFIDLIIKTGGGVGFRMRSPDLVVIRHDGPIEYANMCEEVIARKNPALILCVLARNYADRYEAIKKKCTVDRAVPTQVVCARNMSSKSAMSIATKVAIQINCKLGGSPWTVDIPLPSLMVVGYDVCHDTRSKEKSFGAFVATLDKQMTQYYSIVNAHLSSHMGFNIASAVKKFREKNGTYPARIFIYRDGVGDGQIPYVHSHEVAEIKKKLAEIYAGVEIKLAFIIVSKRINTRIFVQRGRSGENPRPGTVIDDVVTLPERYDFYLVSQNVREGTIAPTSYNVIEDTTGLNPDRIQRLTYKLTHLYFNCSSQVRVPSVCQYAHKLAFLAANSLHNQPHYSLNETLYFL 5guh A 2.40 BS03 MG A 2 D740 S779 K780 D600 S639 K640 A8D8P8 27693359 ISILRTRPEAVTSKKGTSGTPLDLLANYFTVETTPKWGLYQYHVDISPEEDSTGVRKALMRVHSKTLGGYLFDGTVLYTVNRLHPDPMELYSDRKTDNERMRILIKLTCEVSPGDYHYIQIFNIIIRKCFNLLKLQLMGRDYFDPEAKIDIPEFKLQIWPGYKTTINQYEDRLLLVTEIAHKVLRMDTVLQMLSEYAATKKIFLEDVVGKIVMTDYNKRTYRVDDVANVSPKSTFKMRDENITYIEYYYKKYNLRIQDPGQPLLISRSKPREIRAGLPELIYLVPELCRQTGLSDEMRANFKLMRSLDVHTKIGPDKRIEKLNNFNRRFTSTPEVVEELATWSLKLSKELVKIKGRQLPPENIIQANNVKYPAGDTTEGWTRDMRSKHLLAIAQLNSWVVITPERQRRDTESFIDLIIKTGGGVGFRMRSPDLVVIRHDGPIEYANMCEEVIARKNPALILCVLARNYADRYEAIKKKCTVDRAVPTQVVCARNMSSKSAMSIATKVAIQINCKLGGSPWTVDIPLPSLMVVGYDVCHDTRSKEKSFGAFVATLDKQMTQYYSIVNAHLSSHMGFNIASAVKKFREKNGTYPARIFIYRDGVGDGQIPYVHSHEVAEIKKKLAEIYAGVEIKLAFIIVSKRINTRIFVQRGRSGENPRPGTVIDDVVTLPERYDFYLVSQNVREGTIAPTSYNVIEDTTGLNPDRIQRLTYKLTHLYFNCSSQVRVPSVCQYAHKLAFLAANSLHNQPHYSLNETLYFL 5hmq A 2.37 BS01 MG A 1 E134 D165 Q191 E239 E136 D167 Q193 E241 4.2.1.118 Q88JU3 AKMQRSIATVSLSGTLPEKLEAIAAAGFDGVEIFENDLLYYAGSPRQVRQMCADLGIAITLFQPFRDFEGCRRDRLQKNLDRAERKFDLMQELGTDLVLVCSNVQADALGDEQLLVDDLRLLGEHAGKRGLRIGYEALAWGRHVNTYQQVWNLVRQADHPALGVILDSFHTLSLKGDPSAIRDIPGDKIFFVQMADAPILAMDVLEWSRHFRCFPGQGEMDMAGFLAPILATGYRGPLSLEIFNDGFRAAPTRQNAADGLRSLLYLEEQTRLRLEQENTPIEPGVLFSPPPASAYDGVEFLEFAVDEAVGARLGNWLKRLGFAEAGKHRSKEVQLLRQGDINIVLNAEPYSFGHNFFEAHGPSLCATALRVKDQQAALKRATAFRGQPFRGLVGPNECEVPAVRAPDGSLLYLVEQGTLYDTDFSLDNNATATGGLRRIDHMALALPAESLDSWVLFYKSLFDFAADDEVVLPGLVKSRALRSQCGTLRLPLNISENRNTAIAHALSSYRGSGVHHIAFDCDDIFREVARAKLAGVPLLEIPLNYYDDLAARFDFDDEFLSELAYYNVLYDRDAQGGELFHVYTEPFEERFFFEIIQRKAGYAGYGAANVAVRLAAMAKAR 5hmq A 2.37 BS02 MG A 2 H443 H521 E599 H441 H516 E594 4.2.1.118 Q88JU3 AKMQRSIATVSLSGTLPEKLEAIAAAGFDGVEIFENDLLYYAGSPRQVRQMCADLGIAITLFQPFRDFEGCRRDRLQKNLDRAERKFDLMQELGTDLVLVCSNVQADALGDEQLLVDDLRLLGEHAGKRGLRIGYEALAWGRHVNTYQQVWNLVRQADHPALGVILDSFHTLSLKGDPSAIRDIPGDKIFFVQMADAPILAMDVLEWSRHFRCFPGQGEMDMAGFLAPILATGYRGPLSLEIFNDGFRAAPTRQNAADGLRSLLYLEEQTRLRLEQENTPIEPGVLFSPPPASAYDGVEFLEFAVDEAVGARLGNWLKRLGFAEAGKHRSKEVQLLRQGDINIVLNAEPYSFGHNFFEAHGPSLCATALRVKDQQAALKRATAFRGQPFRGLVGPNECEVPAVRAPDGSLLYLVEQGTLYDTDFSLDNNATATGGLRRIDHMALALPAESLDSWVLFYKSLFDFAADDEVVLPGLVKSRALRSQCGTLRLPLNISENRNTAIAHALSSYRGSGVHHIAFDCDDIFREVARAKLAGVPLLEIPLNYYDDLAARFDFDDEFLSELAYYNVLYDRDAQGGELFHVYTEPFEERFFFEIIQRKAGYAGYGAANVAVRLAAMAKAR 5hob F 1.22 BS01 MG F 1 K372 E376 K20 E24 O15350 DTYYLQVRGRKNFEILMELKRSLELMELVPQPLVDSYEQQQQLL 5hru A 1.71 BS01 NUC C 1 M14 V36 V37 F82 T83 D97 L98 L101 I105 L232 S234 Y236 M11 V33 V34 F79 T80 D86 L87 L90 I94 L221 S223 Y225 1.1.1.27 Q4PRK9 KPKIVLVGSGMIGGVMATLIVQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDLKGADVVIVTAGFTKAPRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPVDVMVQLLFEHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNALIVGAHGNKMVLLKRYITVGGIPLQEFINNKKITDEEVEGIFDRTVNTALEIVNLLASPYVAPAAAIIEMAESYLKDIKKVLVCSTLLEGQYGHSNIFGGTPLVIGGTGVEQVIELQLNAEEKTKFDEAVAETKRMKALI 5hru B 1.71 BS01 NUC C 1 G13 M14 D35 V36 V37 K38 M40 K44 A80 G81 F82 I105 G11 M12 D33 V34 V35 K36 M38 K42 A78 G79 F80 I95 1.1.1.27 Q4PRK9 PKPKIVLVGSGMIGGVMATLIVQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDLKGADVVIVTAGFTKANRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPVDVMVQLLFEHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNALIVGAHGNKMVLLKRYITVGGIPLQEFINNKKITDEEVEGIFDRTVNTALEIVNLLASPYVAPAAAIIEMAESYLKDIKKVLVCSTLLEGQYGHSNIFGGTPLVIGGTGVEQVIELQLNAEEKTKFDEAVAETKRMKALI 5hto A 1.90 BS01 NUC C 1 M14 V36 V37 F82 T83 L98 I105 L232 S234 M11 V33 V34 F79 T80 L84 I91 L218 S220 1.1.1.27 Q4PRK9 KPKIVLVGSGMIGGVMATLIVQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDLKGADVVIVTAGFTKAPLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPVDVMVQLLFEHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNALIVGAHGNKMVLLKRYITVGGIPLQEFINNKKITDEEVEGIFDRTVNTALEIVNLLASPYVAPAAAIIEMAESYLKDIKKVLVCSTLLEGQYGHSNIFGGTPLVIGGTGVEQVIELQLNAEEKTKFDEAVAETKRMKALI 5hto D 1.90 BS01 NUC F 1 M14 V36 V37 F82 T83 K84 L98 I105 L232 S234 M11 V33 V34 F79 T80 K81 L86 I93 L220 S222 1.1.1.27 Q4PRK9 KPKIVLVGSGMIGGVMATLIVQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDLKGADVVIVTAGFTKAPDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPVDVMVQLLFEHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNALIVGAHGNKMVLLKRYITVGGIPLQEFINNKKITDEEVEGIFDRTVNTALEIVNLLASPYVAPAAAIIEMAESYLKDIKKVLVCSTLLEGQYGHSNIFGGTPLVIGGTGVEQVIELQLNAEEKTKFDEAVAETKRMKALI 5hw4 A 2.21 BS01 SAM A 1 I21 A93 G94 T95 I98 N99 D100 C123 A124 F144 Y169 A195 E197 L198 E227 M228 V229 I11 A80 G81 T82 I85 N86 D87 C110 A111 F131 Y156 A182 E184 L185 E214 M215 V216 2.1.1.198 P67087 27711192 MGQLYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHEQQKAETLLAKLQEGQNIALVSDAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIEAEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVLIVEGHKAQEED 5igk A 1.70 BS01 BMF A 1 W81 P82 F83 Q85 P86 V87 D88 K91 L92 L94 Y139 N140 I146 W40 P41 F42 Q44 P45 V46 D47 K50 L51 L53 Y98 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 5igl A 2.10 BS01 BMF A 1 F1547 H1549 P1550 V1551 N1552 F1555 V1556 Y1601 N1602 Y1608 F36 H38 P39 V40 N41 F44 V45 Y90 N91 Y97 Q8IZX4 LGTENLYFQSMQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAALEEAEL 5igm A 1.60 BS01 BMF A 1 G159 F160 F161 F163 P164 V165 I169 A170 Y215 N216 Y222 G22 F23 F24 F26 P27 V28 I32 A33 Y78 N79 Y85 Q9H8M2 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMS 5it5 F 2.65 BS01 ZN F 1 C782 C785 C817 C820 C277 C280 C312 C315 Q8VRL1 SAAQKFVKQVIREAFLQDASDIHIEPRQNDVQVRLRIDGALRPYSTLPKGALNAVISVVKIMGGLNIAEKRLPQDGRVRYREGAIDVDLRLSTLPTVYGEKAVMRLLKKASDIPEIEDLGFAPGVFERFKEVISKPYGIFLITGPTGSGKSFTTFSILKRIATPDKNTQTIEDPVEYEIPGINQTQVNPQAGLTFARALRAFLRQDPDIIMVGEIRDSETAKIATEAALTGHLVIATLHTNDAAQAITRLDEMGVEPFNISAALIGVLSQRLVRRVCEHCKVEVKPDPETLRRLGLSEAEIQGARLYKGMGCERCGGTGYKGRYAIHELLVVDDEIRHAIVAGKSATEIKEIARRKGMKTLREDGLYKALQGITTLEEVLARTIE 5it5 F 2.65 BS02 ATP F 1 K613 G652 S653 G654 K655 S656 F657 E681 L777 R828 A830 K108 G147 S148 G149 K150 S151 F152 E176 L272 R323 A325 Q8VRL1 SAAQKFVKQVIREAFLQDASDIHIEPRQNDVQVRLRIDGALRPYSTLPKGALNAVISVVKIMGGLNIAEKRLPQDGRVRYREGAIDVDLRLSTLPTVYGEKAVMRLLKKASDIPEIEDLGFAPGVFERFKEVISKPYGIFLITGPTGSGKSFTTFSILKRIATPDKNTQTIEDPVEYEIPGINQTQVNPQAGLTFARALRAFLRQDPDIIMVGEIRDSETAKIATEAALTGHLVIATLHTNDAAQAITRLDEMGVEPFNISAALIGVLSQRLVRRVCEHCKVEVKPDPETLRRLGLSEAEIQGARLYKGMGCERCGGTGYKGRYAIHELLVVDDEIRHAIVAGKSATEIKEIARRKGMKTLREDGLYKALQGITTLEEVLARTIE 5it5 A 2.65 BS01 AGS A 1 K613 T651 G652 S653 G654 K655 S656 F657 E681 Y682 L777 R828 K108 T146 G147 S148 G149 K150 S151 F152 E176 Y177 L272 R323 Q8VRL1 SAAQKFVKQVIREAFLQDASDIHIEPRQNDVQVRLRIDGALRPYSTLPKGALNAVISVVKIMGGLNIAEKRLPQDGRVRYREGAIDVDLRLSTLPTVYGEKAVMRLLKKASDIPEIEDLGFAPGVFERFKEVISKPYGIFLITGPTGSGKSFTTFSILKRIATPDKNTQTIEDPVEYEIPGINQTQVNPQAGLTFARALRAFLRQDPDIIMVGEIRDSETAKIATEAALTGHLVIATLHTNDAAQAITRLDEMGVEPFNISAALIGVLSQRLVRRVCEHCKVEVKPDPETLRRLGLSEAEIQGARLYKGMGCERCGGTGYKGRYAIHELLVVDDEIRHAIVAGKSATEIKEIARRKGMKTLREDGLYKALQGITTLEEVLARTIE 5it5 B 2.65 BS01 AGS B 1 R582 R595 T651 G652 S653 G654 K655 S656 F657 L777 R828 A830 R77 R90 T146 G147 S148 G149 K150 S151 F152 L272 R323 A325 Q8VRL1 SAAQKFVKQVIREAFLQDASDIHIEPRQNDVQVRLRIDGALRPYSTLPKGALNAVISVVKIMGGLNIAEKRLPQDGRVRYREGAIDVDLRLSTLPTVYGEKAVMRLLKKASDIPEIEDLGFAPGVFERFKEVISKPYGIFLITGPTGSGKSFTTFSILKRIATPDKNTQTIEDPVEYEIPGINQTQVNPQAGLTFARALRAFLRQDPDIIMVGEIRDSETAKIATEAALTGHLVIATLHTNDAAQAITRLDEMGVEPFNISAALIGVLSQRLVRRVCEHCKVEVKPDPETLRRLGLSEAEIQGARLYKGMGCERCGGTGYKGRYAIHELLVVDDEIRHAIVAGKSATEIKEIARRKGMKTLREDGLYKALQGITTLEEVLARTIE 5it5 B 2.65 BS03 MG B 1 S656 E681 S151 E176 Q8VRL1 SAAQKFVKQVIREAFLQDASDIHIEPRQNDVQVRLRIDGALRPYSTLPKGALNAVISVVKIMGGLNIAEKRLPQDGRVRYREGAIDVDLRLSTLPTVYGEKAVMRLLKKASDIPEIEDLGFAPGVFERFKEVISKPYGIFLITGPTGSGKSFTTFSILKRIATPDKNTQTIEDPVEYEIPGINQTQVNPQAGLTFARALRAFLRQDPDIIMVGEIRDSETAKIATEAALTGHLVIATLHTNDAAQAITRLDEMGVEPFNISAALIGVLSQRLVRRVCEHCKVEVKPDPETLRRLGLSEAEIQGARLYKGMGCERCGGTGYKGRYAIHELLVVDDEIRHAIVAGKSATEIKEIARRKGMKTLREDGLYKALQGITTLEEVLARTIE 5it5 C 2.65 BS01 AGS C 1 K613 L624 T651 G652 S653 G654 K655 S656 F657 E681 L777 R828 K108 L119 T146 G147 S148 G149 K150 S151 F152 E176 L272 R323 Q8VRL1 SAAQKFVKQVIREAFLQDASDIHIEPRQNDVQVRLRIDGALRPYSTLPKGALNAVISVVKIMGGLNIAEKRLPQDGRVRYREGAIDVDLRLSTLPTVYGEKAVMRLLKKASDIPEIEDLGFAPGVFERFKEVISKPYGIFLITGPTGSGKSFTTFSILKRIATPDKNTQTIEDPVEYEIPGINQTQVNPQAGLTFARALRAFLRQDPDIIMVGEIRDSETAKIATEAALTGHLVIATLHTNDAAQAITRLDEMGVEPFNISAALIGVLSQRLVRRVCEHCKVEVKPDPETLRRLGLSEAEIQGARLYKGMGCERCGGTGYKGRYAIHELLVVDDEIRHAIVAGKSATEIKEIARRKGMKTLREDGLYKALQGITTLEEVLARTIE 5j1l A 2.27 BS01 ZN A 1 D173 H219 H250 H252 D34 H80 H111 H113 O26068 27711177 GLQKSFIMRLIPNDYPLESYRRVSAVLHNHTGLDLSTAINTPVYASASGVVGLASKGWNGGYGNLIKVFHPFGFKTYYAHLNKIVVKTGEFVKKGQLIGYSGNTGMSTGPHLHYEVRFLDQPINPMSFTKWNMKDFEEVFNKERSIRWQSLITIINRLMQ 5j1l C 2.27 BS01 ZN C 1 H169 D173 H252 H32 D36 H115 O26068 27711177 ITGLQKSFIMRLIPNDYPLESYRRVSAAFNNHTGLDLSTAINTPVYASASGVVGLASKGWNGGYGNLIKVFHPFGFKTYYAHLNKIVVKTGEFVKKGQLIGYSGNTGMSTGPHLHYEVRFLDQPINPMSFTKWNMKDFEEVFNKERSIRWQSLITIINRLMQ 5j31 A 2.40 BS01 III C 1 R41 N42 V46 K49 K120 Y128 P165 L172 N173 D213 L216 I217 N224 R41 N42 V46 K49 K120 Y128 P165 L172 N173 D212 L215 I216 N223 P63104 27596722 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLEESYKDSTLIMQLLRDNLTLWTS 5j31 B 2.40 BS01 III D 1 R41 N42 V46 K49 F117 K120 Y128 G169 L172 N173 D213 N224 R41 N42 V46 K49 F117 K120 Y128 G169 L172 N173 D212 N223 P63104 27596722 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLEESYKDSTLIMQLLRDNLTLWTS 5j3r A 2.46 BS01 FES A 1 C136 S137 Y138 C25 S26 Y27 Q12438 27710937 AFNVQKEYSLILDLSPIIIFSKSTCSYSKGMKELLENEYQFIPNYYIIELDKHGHGEELQEYIKLVTGRGTVPNLLVNGVSRGGNEEIKKLHTQGKLLESLQVWSDGKFSVEQR 5j4h A 1.37 BS01 1F1 A 1 M169 Y170 I171 A201 Y202 A203 L214 Q217 A218 M62 Y63 I64 A94 Y95 A96 L107 Q110 A111 O74036 27725183 ATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSAMYIDTENTFRPERLREIAQNRGLDPDEVLDNVAYARAFNSNHQMLLVQQAEDMIKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLADLHRLANLYDIAVFVTNQVHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED 5j4h A 1.37 BS02 CA A 1 G141 G143 K144 T145 Q146 G34 G36 K37 T38 Q39 O74036 27725183 ATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSAMYIDTENTFRPERLREIAQNRGLDPDEVLDNVAYARAFNSNHQMLLVQQAEDMIKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLADLHRLANLYDIAVFVTNQVHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED 5j5r A 1.60 BS01 6G1 A 1 A145 G194 V195 G196 T203 M284 G285 E318 A132 G181 V182 G183 T190 M271 G272 E281 1.1.1.205 G7CNL4 27726334 PVPTGGDDPTKIAMLGLTFDDVLLLPAASDVLPANADTSSQLTKKIRLKVPLVSSAMDTVTEARMAIAMARAGGMGVLHRNLPVAEQAAQVETVKRSGGLLVGAAVGVGDDAWERAMALRDAGVDVLVVDTAHAHNRKVLDMVHRLKTTVGDEIEVVGGNVATRAAAAALVEAGADAVKVGVGPGSICTTRVVAGVGAPQITAILEAVAACAPHGVPVIADGGLQYSGDIAKALAAGASTAMLGSLLAGTAESPGELILVNGKQFKSYRGMGSLGAMQVPEGIEGRVPFRGPLSTVIHQLVGGLRAAMGYTGSATIEELQQAQFVQITAAGL 5j5r A 1.60 BS02 IMP A 1 S68 M70 G198 S199 I200 C201 D234 G235 G236 M255 G257 S258 Y281 G283 M284 G285 E318 G319 S55 M57 G185 S186 I187 C188 D221 G222 G223 M242 G244 S245 Y268 G270 M271 G272 E281 G282 1.1.1.205 G7CNL4 27726334 PVPTGGDDPTKIAMLGLTFDDVLLLPAASDVLPANADTSSQLTKKIRLKVPLVSSAMDTVTEARMAIAMARAGGMGVLHRNLPVAEQAAQVETVKRSGGLLVGAAVGVGDDAWERAMALRDAGVDVLVVDTAHAHNRKVLDMVHRLKTTVGDEIEVVGGNVATRAAAAALVEAGADAVKVGVGPGSICTTRVVAGVGAPQITAILEAVAACAPHGVPVIADGGLQYSGDIAKALAAGASTAMLGSLLAGTAESPGELILVNGKQFKSYRGMGSLGAMQVPEGIEGRVPFRGPLSTVIHQLVGGLRAAMGYTGSATIEELQQAQFVQITAAGL 5jq0 A 1.40 BS02 6M4 A 1 Q92 H94 H96 H119 V121 L141 L198 T199 T200 Q89 H91 H93 H116 V118 L137 L194 T195 T196 4.2.1.1 P00918 27722534 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5jqt A 1.36 BS02 6M4 A 1 Q92 H94 H96 H119 V121 L141 V143 L198 T199 T200 Q92 H94 H96 H119 V121 L140 V142 L197 T198 T199 4.2.1.1 P00918 27722534 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5jqt A 1.36 BS06 6M9 A 2 H4 H10 N11 K18 D19 H4 H10 N11 K18 D19 4.2.1.1 P00918 27722534 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5jqt A 1.36 BS07 6M4 A 3 H4 N11 F231 N232 E239 H4 N11 F230 N231 E238 4.2.1.1 P00918 27722534 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5jqt A 1.36 BS08 6M4 A 4 G8 K9 H10 N11 G8 K9 H10 N11 4.2.1.1 P00918 27722534 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5juy A 4.10 BS01 DTP A 1 V125 F126 V127 C158 G159 K160 S161 R265 P321 Y359 V21 F22 V23 C54 G55 K56 S57 R161 P217 Y255 O14727 27697150 GITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE 5juy H 4.10 BS01 HEC H 1 K13 C14 C17 H18 T28 P30 L32 L35 T40 G41 F46 Y48 T49 N52 W59 L68 T78 K79 M80 I81 F82 I85 L94 K13 C14 C17 H18 T28 P30 L32 L35 T40 G41 F46 Y48 T49 N52 W59 L68 T78 K79 M80 I81 F82 I85 L94 P62894 27697150 GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFSYTDANKNKGITWGEETLMEYLENPKKYIPGTKMIFAGIKKKGEREDLIAYLKKATNE 5jxu A 1.75 BS01 HEM A 1 N214 Q218 L219 G221 T222 V223 I256 M258 R277 H312 I313 A316 H317 M325 R327 F348 V362 Q363 L366 L373 T377 N171 Q175 L176 G178 T179 V180 I213 M215 R234 H269 I270 A273 H274 M282 R284 F305 V319 Q320 L323 L330 T334 D1A807 TTGTATEPFHGPHQAGIATPPQAHAVFLGLDLRKGTGRKELGRLMRLLTDDARRLTQGRPALADPEPDLAPLPSRLTFTFGFGPGLFKAAGLEKQRPEGLRPLPPFKVDRLEDRWSGGDLLVQICCDDPITLAHALRMTVKDARAFTRVRWVQRGFRRSPGVQSSGATQRNLMGQLDGTVNPVPGTADFDQAVWVQDGPEWLRGGTTLVLRRIRMELEKWDEADPAGKEFAVGRRLTSGAPLTGRHEHDEPDFDAVDSAGFPVIAENAHIRLAHVDSPRLRMLRRPYNYDEGLTADGRSDAGLLFAAYQADIDRQFIPVQRRLDEGGDLLNLWTTPIGSAVFAIPPGCDENGWIGQGLLG 5jze A 2.47 BS01 AYE B 1 V38 G41 C43 W102 A153 H154 V35 G38 C40 W99 A150 H151 J3RTH4 27412597 VNRLDAIVWENIEGNLSRAFLTLDLHAFFNVNKEVGDGNCFYRALSRLHSESRTSNEHLYYRLLIPDAVDKYFDIEPEAIGLGLNKQEYVSKAILDGEWAGSLEASMLSKFLDITIIIWIVDDSGTIISANRYGEGRPSQAYNLCMVGNAHFDSLYIRV 5k1p A 1.50 BS01 ANP A 1 R330 E332 H338 L339 F342 E396 L397 S398 S399 G421 F422 G423 R426 I437 R142 E144 H150 L151 F154 E208 L209 S210 S211 G233 F234 G235 R238 I249 6.1.1.26 Q8PWY1 27711380 ALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLAFAQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTNLHHHH 5k4x A 1.37 BS01 6Q9 A 1 R93 A145 G194 V195 G196 T203 M284 G285 E318 R79 A131 G180 V181 G182 T189 M270 G271 E280 1.1.1.205,1.1.1.205 A0A100XBM0 27704782 VPTGGDDPTKIAMLGLTFDDVLLLPAASDVLPANADTSSQLTKKIRLKVPLVSSAMDTVTEARMAIAMARAGGMGVLHRNLPVAEQAAQVETVKRSGGLLVGAAVGVGDDAWERAMALRDAGVDVLVVDTAHAHNRKVLDMVHRLKTTVGDEIEVVGGNVATRAAAAALVEAGADAVKVGVGPGSICTTRVVAGVGAPQITAILEAVAACAPHGVPVIADGGLQYSGDIAKALAAGASTAMLGSLLAGTAESPGELILVNGKQFKSYRGMGSLGAMQVPEGIEGRVPFRGPLSTVIHQLVGGLRAAMGYTGSATIEELQQAQFVQITAAG 5k4z A 1.64 BS02 6Q8 A 1 T144 A145 H146 N149 V152 G194 V195 G196 T203 M284 G285 E318 T130 A131 H132 N135 V138 G180 V181 G182 T189 M270 G271 E281 1.1.1.205,1.1.1.205 A0A100XBM0 27704782 VPTGGDDPTKIAMLGLTFDDVLLLPAASDVLPANADTSSQLTKKIRLKVPLVSSAMDTVTEARMAIAMARAGGMGVLHRNLPVAEQAAQVETVKRSGGLLVGAAVGVGDDAWERAMALRDAGVDVLVVDTAHAHNRKVLDMVHRLKTTVGDEIEVVGGNVATRAAAAALVEAGADAVKVGVGPGSICTTRVVAGVGAPQITAILEAVAACAPHGVPVIADGGLQYSGDIAKALAAGASTAMLGSLLAGTAESPGELILVNGKQFKSYRGMGSLGAMQLVPEGIEGRVPFRGPLSTVIHQLVGGLRAAMGYTGSATIEELQQAQFVQITAAGL 5kho C 2.78 BS02 GNP C 1 G13 V14 G15 K16 S17 A18 F28 V29 E30 Y32 P34 T35 G60 N116 K117 D119 L120 S147 A148 G13 V14 G15 K16 S17 A18 F28 V29 E30 Y32 P34 T35 G60 N114 K115 D117 L118 S145 A146 P61224 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR 5kho D 2.78 BS02 GNP D 1 G13 G15 K16 S17 A18 F28 V29 E30 Y32 T35 G60 N116 K117 D119 L120 S147 A148 G13 G15 K16 S17 A18 F28 V29 E30 Y32 T35 G60 N116 K117 D119 L120 S147 A148 P61224 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR 5kj7 A 3.50 BS01 CA A 1 K59 E62 K33 E36 P63025 GSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYW 5kj7 F 3.50 BS03 CA F 3 D303 D309 Y364 D161 D165 Y220 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5kj7 F 3.50 BS04 CA F 4 F153 F252 G253 F13 F112 G113 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5kj8 E 4.10 BS04 CA E 4 D172 D178 D230 F231 D32 D38 D90 F91 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5kj8 F 4.10 BS02 CA F 2 D172 D230 D232 D238 D32 D90 D92 D98 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5kj8 F 4.10 BS04 CA F 4 D172 T176 S177 D178 D230 D32 T36 S37 D38 D90 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5kj8 K 4.10 BS01 CA K 1 M302 D303 L307 S308 D309 D363 M162 D163 L167 S168 D169 D223 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5kj8 K 4.10 BS04 CA K 4 D172 D178 F231 D32 D38 F91 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ks8 C 3.01 BS01 PYR C 1 Q16 G48 L81 R83 F116 K174 M176 Q14 G46 L79 R81 F114 K172 M174 Q1H157 27708276 KVHVTDVVLRDGHQSLIATRMRTDDMLPICSKLDAVGYWSLEAWGGATFDACVRYLREDPWERLKKLRKALPNSRLQMLLRGQNLLGYRHYSDDVVRAFVQKSADNGIDVFRIFDAMNDLRNLKVSIESVKAVGKHAEGTISYTTSPVHDIPYFVNLAKELESFGCDTIAIKDMASLLTPQVTGDLVKALREAVSLPIHLHAHATSGLASMSIQRAVDNGVAIVDGCISSFAEGASLPATESIVAALKGTEYDTGLDIGLLQEISAYFREVRKKYWQFESEFTGVDTRVLVNQVPGGMISNLSNQLKEQGALDRMDAVLDEIPRVREDLGYPPLVTPTSQIVGTQAVLNVMTGARYKSVTNEVKNYLLGHYGKAPSTVNPDVRNLAVGNAQVIECRPADLLTAEMEKLRNEVEGLAASAADVLTYAMFPDLAKTFLQERNAGSLKPEPLLDKEAVTSRESHSRFAPTEFNVTLHGETFHIKLTGSGHHGEEQRPFYVSVDGVTEEVVVEILNEAKRKASSAASSGRPRPTHAGCVTTAMPGTIVDVKVNVGDKVSAGDAVLVIEAMKMENEIQASKSGVVVAINVKKGDSVTPDEALLEIQPD 5ks8 C 3.01 BS02 MN C 1 R12 D13 K174 M176 H203 H205 R10 D11 K172 M174 H201 H203 Q1H157 27708276 KVHVTDVVLRDGHQSLIATRMRTDDMLPICSKLDAVGYWSLEAWGGATFDACVRYLREDPWERLKKLRKALPNSRLQMLLRGQNLLGYRHYSDDVVRAFVQKSADNGIDVFRIFDAMNDLRNLKVSIESVKAVGKHAEGTISYTTSPVHDIPYFVNLAKELESFGCDTIAIKDMASLLTPQVTGDLVKALREAVSLPIHLHAHATSGLASMSIQRAVDNGVAIVDGCISSFAEGASLPATESIVAALKGTEYDTGLDIGLLQEISAYFREVRKKYWQFESEFTGVDTRVLVNQVPGGMISNLSNQLKEQGALDRMDAVLDEIPRVREDLGYPPLVTPTSQIVGTQAVLNVMTGARYKSVTNEVKNYLLGHYGKAPSTVNPDVRNLAVGNAQVIECRPADLLTAEMEKLRNEVEGLAASAADVLTYAMFPDLAKTFLQERNAGSLKPEPLLDKEAVTSRESHSRFAPTEFNVTLHGETFHIKLTGSGHHGEEQRPFYVSVDGVTEEVVVEILNEAKRKASSAASSGRPRPTHAGCVTTAMPGTIVDVKVNVGDKVSAGDAVLVIEAMKMENEIQASKSGVVVAINVKKGDSVTPDEALLEIQPD 5ks8 D 3.01 BS01 BTI C 1 Q16 A49 D52 Y57 R83 Y90 M300 T338 S341 Q342 Q15 A48 D51 Y56 R82 Y89 M299 T337 S340 Q341 Q1H157 27708276 AKVHVTDVVLRDGHQSLIATRMRTDDMLPICSKLDAVGYWSLEAWGGATFDACVRYLREDPWERLKKLRKALPNSRLQMLLRGQNLLGYRHYSDDVVRAFVQKSADNGIDVFRIFDAMNDLRNLKVSIESVKAVGKHAEGTISYTTSPVHDIPYFVNLAKELESFGCDTIAIKDMASLLTPQVTGDLVKALREAVSLPIHLHAHATSGLASMSIQRAVDNGVAIVDGCISSFAEGASLPATESIVAALKGTEYDTGLDIGLLQEISAYFREVRKKYWQFESEFTGVDTRVLVNQVPGGMISNLSNQLKEQGALDRMDAVLDEIPRVREDLGYPPLVTPTSQIVGTQAVLNVMTGARYKSVTNEVKNYLLGHYGKAPSTVNPDVRNLAVGNAQVIECRPADLLTAEMEKLRNEVEGLAASAADVLTYAMFPDLAKTFLQERNAGSLKPEPLLDKEAVTSRESHSRFAPTEFNVTLHGETFHIKLTPFYVSVDGVTEEVVVEILNRPRPTHAGCVTTAMPGTIVDVKVNVGDKVSAGDAVLVIEAMKMENEIQASKSGVVVAINVKKGDSVTPDEALLEIQP 5ks8 D 3.01 BS02 PYR D 1 R12 Q16 G48 A49 L81 R83 F116 T338 R11 Q15 G47 A48 L80 R82 F115 T337 Q1H157 27708276 AKVHVTDVVLRDGHQSLIATRMRTDDMLPICSKLDAVGYWSLEAWGGATFDACVRYLREDPWERLKKLRKALPNSRLQMLLRGQNLLGYRHYSDDVVRAFVQKSADNGIDVFRIFDAMNDLRNLKVSIESVKAVGKHAEGTISYTTSPVHDIPYFVNLAKELESFGCDTIAIKDMASLLTPQVTGDLVKALREAVSLPIHLHAHATSGLASMSIQRAVDNGVAIVDGCISSFAEGASLPATESIVAALKGTEYDTGLDIGLLQEISAYFREVRKKYWQFESEFTGVDTRVLVNQVPGGMISNLSNQLKEQGALDRMDAVLDEIPRVREDLGYPPLVTPTSQIVGTQAVLNVMTGARYKSVTNEVKNYLLGHYGKAPSTVNPDVRNLAVGNAQVIECRPADLLTAEMEKLRNEVEGLAASAADVLTYAMFPDLAKTFLQERNAGSLKPEPLLDKEAVTSRESHSRFAPTEFNVTLHGETFHIKLTPFYVSVDGVTEEVVVEILNRPRPTHAGCVTTAMPGTIVDVKVNVGDKVSAGDAVLVIEAMKMENEIQASKSGVVVAINVKKGDSVTPDEALLEIQP 5ks8 D 3.01 BS03 MN D 1 R12 D13 K174 H203 H205 R11 D12 K173 H202 H204 Q1H157 27708276 AKVHVTDVVLRDGHQSLIATRMRTDDMLPICSKLDAVGYWSLEAWGGATFDACVRYLREDPWERLKKLRKALPNSRLQMLLRGQNLLGYRHYSDDVVRAFVQKSADNGIDVFRIFDAMNDLRNLKVSIESVKAVGKHAEGTISYTTSPVHDIPYFVNLAKELESFGCDTIAIKDMASLLTPQVTGDLVKALREAVSLPIHLHAHATSGLASMSIQRAVDNGVAIVDGCISSFAEGASLPATESIVAALKGTEYDTGLDIGLLQEISAYFREVRKKYWQFESEFTGVDTRVLVNQVPGGMISNLSNQLKEQGALDRMDAVLDEIPRVREDLGYPPLVTPTSQIVGTQAVLNVMTGARYKSVTNEVKNYLLGHYGKAPSTVNPDVRNLAVGNAQVIECRPADLLTAEMEKLRNEVEGLAASAADVLTYAMFPDLAKTFLQERNAGSLKPEPLLDKEAVTSRESHSRFAPTEFNVTLHGETFHIKLTPFYVSVDGVTEEVVVEILNRPRPTHAGCVTTAMPGTIVDVKVNVGDKVSAGDAVLVIEAMKMENEIQASKSGVVVAINVKKGDSVTPDEALLEIQP 5ks8 F 3.01 BS01 MN F 1 R12 D13 K174 M176 H203 H205 R10 D11 K172 M174 H201 H203 Q1H157 27708276 KVHVTDVVLRDGHQSLIATRMRTDDMLPICSKLDAVGYWSLEAWGGATFDACVRYLREDPWERLKKLRKALPNSRLQMLLRGQNLLGYRHYSDDVVRAFVQKSADNGIDVFRIFDAMNDLRNLKVSIESVKAVGKHAEGTISYTTSPVHDIPYFVNLAKELESFGCDTIAIKDMASLLTPQVTGDLVKALREAVSLPIHLHAHATSGLASMSIQRAVDNGVAIVDGCISSFAEGASLPATESIVEYDTGLDIGLLQEISAYFREVRKKYWQFESEFTGVDTRTNEVKNYLLGHYGKAPSTVNPDVRNQVIECRPADLLTAEMEKLRNEVEGLAASAADVLTYAMFPDLAKTFLQERNAGSLKPEPLLDAPTEFNVTLHGETFHIKLTFYVSVDGVTEEVVVEILGRPRPTHAGCVTTAMPGTIVDVKVNVGDKVSAGDAVLVIEAMKMENEIQASKSGVVVAINVKKGDSVTPDEALLEIQP 5l1e A 4.37 BS01 6ZQ A 1 K509 K511 S516 F517 D519 P520 Y616 L620 F623 L624 N791 K500 K502 S507 F508 D510 P511 Y577 L581 F584 L585 N752 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1e B 4.37 BS01 6ZQ B 1 K511 S516 F517 D519 P520 Y616 F623 L624 R628 N791 K502 S507 F508 D510 P511 Y573 F580 L581 R585 N748 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1e C 4.37 BS01 6ZQ C 1 S516 F517 D519 P520 W526 Y616 L620 F623 N791 S507 F508 D510 P511 W517 Y573 L577 F580 N748 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1e D 4.37 BS01 6ZQ D 1 K509 S510 S516 F517 D519 P520 Y616 F623 L624 E627 V630 N791 K500 S501 S507 F508 D510 P511 Y577 F584 L585 E588 V591 N752 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1f A 4.00 BS01 6ZP A 1 K511 S516 F517 D519 P520 Y616 F623 N791 K502 S507 F508 D510 P511 Y577 F584 N752 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1f B 4.00 BS01 6ZP B 1 S510 K511 S516 F517 L518 D519 P520 Y616 F623 N791 S501 K502 S507 F508 L509 D510 P511 Y573 F580 N748 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1f C 4.00 BS01 6ZP C 1 K511 S516 F517 L518 D519 P520 Y616 F623 S788 N791 K502 S507 F508 L509 D510 P511 Y573 F580 S745 N748 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1f D 4.00 BS01 6ZP D 1 K511 S516 F517 D519 P520 Y616 N619 F623 S788 N791 K502 S507 F508 D510 P511 Y577 N580 F584 S749 N752 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1g A 4.51 BS01 GYB A 1 S516 D519 P520 L620 F623 L787 S788 S790 N791 S507 D510 P511 L581 F584 L748 S749 S751 N752 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1g B 4.51 BS01 GYB A 2 I613 S614 I570 S571 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1g B 4.51 BS02 GYB B 1 S510 S516 D519 P520 Y616 L620 F623 L624 S788 N791 S501 S507 D510 P511 Y573 L577 F580 L581 S745 N748 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1g C 4.51 BS01 GYB A 3 W606 T609 L610 I613 W564 T567 L568 I571 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1g C 4.51 BS02 GYB C 1 S516 F517 D519 P520 Y616 F623 S788 N791 S507 F508 D510 P511 Y574 F581 S746 N749 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1g D 4.51 BS02 GYB A 4 W606 I613 W567 I574 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1g D 4.51 BS03 GYB D 1 S516 D519 P520 Y616 F623 L624 S788 N791 S507 D510 P511 Y577 F584 L585 S749 N752 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1h A 3.80 BS01 GYK A 1 S516 F517 D519 P520 L620 F623 S788 N791 S507 F508 D510 P511 L577 F580 S745 N748 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1h B 3.80 BS01 GYK B 1 S510 S516 F517 D519 P520 Y616 L620 F623 S788 N791 S501 S507 F508 D510 P511 Y573 L577 F580 S745 N748 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1h C 3.80 BS01 GYK C 1 P512 S516 D519 P520 F623 S788 S790 N791 P503 S507 D510 P511 F580 S745 S747 N748 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5l1h D 3.80 BS01 GYK D 1 K511 S516 D519 P520 Y616 F623 L624 M629 S788 N791 K502 S507 D510 P511 Y576 F583 L584 M589 S748 N751 P19491 27618672 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSIFNSLWFSLGAFMQQGSPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 5lga A 2.50 BS01 III B 1 I270 K274 F279 A284 Q287 I288 L291 K292 P442 E446 V447 E451 I56 K60 F65 A70 Q73 I74 L77 K78 P228 E232 V233 E237 Q9PTN2 27650654 HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV 5lga A 2.50 BS02 6VH A 1 Y175 Y179 L255 L261 V262 S265 I296 R302 S303 S306 W314 C316 H333 L337 L341 H423 Y427 V444 F448 Y22 Y26 L41 L47 V48 S51 I82 R88 S89 S92 W100 C102 H119 L123 L127 H209 Y213 V230 F234 Q9PTN2 27650654 HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV 5lmc A 1.90 BS01 FEO A 1 H79 E81 D83 H84 H147 D166 H227 H78 E80 D82 H83 H146 D165 H226 Q46877 27725182 SIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGIAETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALKLCREHGREIARQWALAP 5lmd A 1.70 BS02 RC4 A 1 H94 H96 H119 V121 F131 V135 L198 T199 T200 P202 W209 H91 H93 H116 V118 F127 V131 L194 T195 T196 P198 W205 4.2.1.1 P00918 27722534 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5lva A 2.53 BS01 FMN A 1 H9 S15 V16 V17 N18 P65 L66 Y67 W68 Y69 S106 A107 G108 A109 Y114 A151 H9 S15 V16 V17 N18 P65 L66 Y67 W68 Y69 S106 A107 G108 A109 Y114 A151 Q75V96 27714222 MKVLVLAFHPNMEQSVVNRAFADTLKDAPGITLRDLYQEYPDEAIDVEKEQKLCEEHDRIVFQFPLYWYSSPPLLKKWLDHVLLYGWAYGTNGTALRGKEFMVAVSAGAPEEAYQAGGSNHYAISELLRPFQATSNFIGTTYLPPYVFYQAGTAGKSELAEGATQYREHVLKSF 5lvl A 1.40 BS01 537 A 1 L88 V96 A109 L159 S160 Y161 A162 G165 L212 T222 L15 V23 A36 L86 S87 Y88 A89 G92 L139 T149 2.7.11.1 O15530 27693059 PRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvm A 1.26 BS01 ADE A 1 V96 A109 V143 L159 S160 Y161 A162 L212 V21 A34 V68 L84 S85 Y86 A87 L137 2.7.11.1 O15530 27693059 KKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvn A 1.38 BS01 ADN A 1 G89 V96 A109 V143 L159 S160 Y161 A162 E166 E209 L212 G14 V21 A34 V68 L84 S85 Y86 A87 E91 E134 L137 2.7.11.1 O15530 27693059 KKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvo A 1.09 BS01 ATP A 1 G89 E90 G91 S92 S94 V96 A109 K111 V143 L159 S160 Y161 A162 E166 L212 G16 E17 G18 S19 S21 V23 A36 K38 V70 L86 S87 Y88 A89 E93 L139 2.7.11.1 O15530 27693059 PRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvo A 1.09 BS02 78W A 1 K115 I118 I119 V127 T128 T148 F149 Q150 L155 Y156 F157 K42 I45 I46 V54 T55 T75 F76 Q77 L82 Y83 F84 2.7.11.1 O15530 27693059 PRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvp A 2.50 BS01 III F 1 K115 V124 R131 S135 L145 Y146 F147 T148 F149 Q150 L155 F157 K41 V50 R57 S61 L71 Y72 F73 T74 F75 Q76 L81 F83 2.7.11.1 O15530 27693059 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLNSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvp B 2.50 BS01 III G 1 K115 V124 R131 L145 Y146 F147 T148 Q150 L155 F157 K42 V51 R58 L72 Y73 F74 T75 Q77 L82 F84 2.7.11.1 O15530 27693059 PRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvp C 2.50 BS01 III E 1 K115 V124 R131 L145 F147 T148 F149 Q150 L155 F157 K41 V50 R57 L71 F73 T74 F75 Q76 L81 F83 2.7.11.1 O15530 27693059 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLNSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvp C 2.50 BS02 ATP C 1 G89 G91 S92 S94 V96 A109 K111 S160 Y161 A162 E166 L212 G15 G17 S18 S20 V22 A35 K37 S86 Y87 A88 E92 L138 2.7.11.1 O15530 27693059 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLNSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvp D 2.50 BS01 III H 1 R75 K76 K77 K115 V124 R131 S135 L145 F147 T148 F149 Q150 L155 F157 R2 K3 K4 K42 V51 R58 S62 L72 F74 T75 F76 Q77 L82 F84 2.7.11.1 O15530 27693059 PRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLNSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lvp D 2.50 BS02 ATP D 1 L88 G89 E90 G91 S94 V96 A109 K111 S160 Y161 A162 L212 L15 G16 E17 G18 S21 V23 A36 K38 S87 Y88 A89 L139 2.7.11.1 O15530 27693059 PRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLNSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEGLIFAKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT 5lxv B 2.40 BS01 CA B 1 D892 D894 D896 E898 D903 D4 D6 D8 E10 D15 VYGDLDGDGEVDVFDLILMRKAVENGDTERFEAADLNCDGVIDSDDLTYHSEYLHGIRKTLPVEY 5lxv B 2.40 BS02 CA B 2 D923 N925 D927 V929 D934 D35 N37 D39 V41 D46 VYGDLDGDGEVDVFDLILMRKAVENGDTERFEAADLNCDGVIDSDDLTYHSEYLHGIRKTLPVEY 5szl A 4.20 BS01 CA A 1 N208 N210 D240 D242 N246 D295 L299 N207 N209 D239 D241 N245 D294 L298 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLV 5szl A 4.20 BS02 CA A 2 E116 E175 D206 V207 D209 D242 E115 E174 D205 V206 D208 D241 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLV 5szl A 4.20 BS03 CA A 3 E116 D173 R174 E175 D209 E115 D172 R173 E174 D208 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLV 5szl A 4.20 BS04 CA A 4 E9 E65 D97 I98 D100 D133 E8 E64 D96 I97 D99 D132 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLV 5szl A 4.20 BS05 CA A 5 N99 N101 D131 D133 N137 D188 N98 N100 D130 D132 N136 D187 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLV 5szl A 4.20 BS06 CA A 6 E9 E10 R61 D63 E65 D100 E8 E9 R60 D62 E64 D99 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLV 5szl A 4.20 BS08 CA A 8 E225 D280 F281 E282 D314 N315 E224 D279 F280 E281 D313 N314 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLV 5szl B 4.20 BS03 CA B 3 E9 E10 D63 E65 D100 N101 E8 E9 D62 E64 D99 N100 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLL 5szl B 4.20 BS06 CA B 6 E116 D173 E175 D209 E115 D172 E174 D208 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLL 5szl B 4.20 BS07 CA B 7 E225 D280 E282 D314 N315 D347 E224 D279 E281 D313 N314 D346 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLL 5szl B 4.20 BS08 CA B 8 E225 D311 V312 D314 D347 E224 D310 V311 D313 D346 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLL 5szl C 4.20 BS03 CA C 3 E116 D173 E175 D209 N210 E115 D172 E174 D208 N209 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLVTDIND 5szl C 4.20 BS04 CA C 4 E9 E65 D97 I98 D100 N101 D133 E8 E64 D96 I97 D99 N100 D132 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLVTDIND 5szl C 4.20 BS06 CA C 6 E9 E10 D63 E65 D100 E8 E9 D62 E64 D99 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLVTDIND 5szl D 4.20 BS08 CA D 8 E225 D280 F281 E282 D314 E224 D279 F280 E281 D313 A0A0A6YW27 NIRYSVPEETDKGSFVGSIAKDLGLETRELMERGIRIVSRGRSQLFSLNPRSGSLVTAGRIDREELCAQSTPCVVSFNILMEDEMKLLPIEVEIIDINDNTPQFQLEELELKMSEITTPGTRIPLPLGQDLDVGINSLQSYQLSANPHFSLDVQQGPEGPQQPEMVLQRPLDREKDAVHYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKAEYHVSVPENVPLGTRLLKVNATDPDEGANGRVTYSFHKVDHSVVRKFQLDAYTGELSNKEPLDFEEYKVYPMEIQAQDGAGLMARAKVLVTVLDVNDNAPEVGITSVTNTVPENFPPGTTIALISVHDQDADNNGHITCSIPGNLPFKLEKLVDNYYRLVTERTLDREQSSRHNITITATDQGTPPLSTQAHISLLVTDI 5szm A 3.60 BS01 CA A 1 E8 E9 D62 E64 D99 E8 E9 D62 E64 D99 Q91XY0 QIRYSVPEETDKGTVVGNISKDLGLEPRELAERGVRIVSRGRSQLFSLNPRGGSLVTAGRIDREELCAQSTPCLVNINILVEEKGKLFGVEIEITDINDNNPKFHVGDLEVKINEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTASDGGEPRRSSTALIQITVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGVNGKVTYKFRKINEKQSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDVGALLGRSKVIIMVEDVNDNRPEVTITSLFNPVLENSLPGTVIAFLNVHDQDSGKNGQVVCYTHDNLPFKLEKSIDNYYRLVTWKYLDREKVSTYNITVIASDLGAPPLSTETYIALTVADT 5szm A 3.60 BS02 CA A 2 E8 E64 D96 I97 N98 D99 D132 E8 E64 D96 I97 N98 D99 D132 Q91XY0 QIRYSVPEETDKGTVVGNISKDLGLEPRELAERGVRIVSRGRSQLFSLNPRGGSLVTAGRIDREELCAQSTPCLVNINILVEEKGKLFGVEIEITDINDNNPKFHVGDLEVKINEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTASDGGEPRRSSTALIQITVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGVNGKVTYKFRKINEKQSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDVGALLGRSKVIIMVEDVNDNRPEVTITSLFNPVLENSLPGTVIAFLNVHDQDSGKNGQVVCYTHDNLPFKLEKSIDNYYRLVTWKYLDREKVSTYNITVIASDLGAPPLSTETYIALTVADT 5szm A 3.60 BS03 CA A 3 N98 N100 D130 D132 N136 D187 N98 N100 D130 D132 N136 D187 Q91XY0 QIRYSVPEETDKGTVVGNISKDLGLEPRELAERGVRIVSRGRSQLFSLNPRGGSLVTAGRIDREELCAQSTPCLVNINILVEEKGKLFGVEIEITDINDNNPKFHVGDLEVKINEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTASDGGEPRRSSTALIQITVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGVNGKVTYKFRKINEKQSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDVGALLGRSKVIIMVEDVNDNRPEVTITSLFNPVLENSLPGTVIAFLNVHDQDSGKNGQVVCYTHDNLPFKLEKSIDNYYRLVTWKYLDREKVSTYNITVIASDLGAPPLSTETYIALTVADT 5szm A 3.60 BS04 CA A 4 E115 E174 D205 T206 D208 D241 E115 E174 D205 T206 D208 D241 Q91XY0 QIRYSVPEETDKGTVVGNISKDLGLEPRELAERGVRIVSRGRSQLFSLNPRGGSLVTAGRIDREELCAQSTPCLVNINILVEEKGKLFGVEIEITDINDNNPKFHVGDLEVKINEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTASDGGEPRRSSTALIQITVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGVNGKVTYKFRKINEKQSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDVGALLGRSKVIIMVEDVNDNRPEVTITSLFNPVLENSLPGTVIAFLNVHDQDSGKNGQVVCYTHDNLPFKLEKSIDNYYRLVTWKYLDREKVSTYNITVIASDLGAPPLSTETYIALTVADT 5szm A 3.60 BS06 CA A 6 E115 D172 E174 D208 N209 E115 D172 E174 D208 N209 Q91XY0 QIRYSVPEETDKGTVVGNISKDLGLEPRELAERGVRIVSRGRSQLFSLNPRGGSLVTAGRIDREELCAQSTPCLVNINILVEEKGKLFGVEIEITDINDNNPKFHVGDLEVKINEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTASDGGEPRRSSTALIQITVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGVNGKVTYKFRKINEKQSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDVGALLGRSKVIIMVEDVNDNRPEVTITSLFNPVLENSLPGTVIAFLNVHDQDSGKNGQVVCYTHDNLPFKLEKSIDNYYRLVTWKYLDREKVSTYNITVIASDLGAPPLSTETYIALTVADT 5szm A 3.60 BS07 CA A 7 E224 D279 E281 D313 E224 D279 E281 D313 Q91XY0 QIRYSVPEETDKGTVVGNISKDLGLEPRELAERGVRIVSRGRSQLFSLNPRGGSLVTAGRIDREELCAQSTPCLVNINILVEEKGKLFGVEIEITDINDNNPKFHVGDLEVKINEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTASDGGEPRRSSTALIQITVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGVNGKVTYKFRKINEKQSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDVGALLGRSKVIIMVEDVNDNRPEVTITSLFNPVLENSLPGTVIAFLNVHDQDSGKNGQVVCYTHDNLPFKLEKSIDNYYRLVTWKYLDREKVSTYNITVIASDLGAPPLSTETYIALTVADT 5szm A 3.60 BS08 CA A 8 E224 E281 D310 V311 N312 D313 D346 E224 E281 D310 V311 N312 D313 D346 Q91XY0 QIRYSVPEETDKGTVVGNISKDLGLEPRELAERGVRIVSRGRSQLFSLNPRGGSLVTAGRIDREELCAQSTPCLVNINILVEEKGKLFGVEIEITDINDNNPKFHVGDLEVKINEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTASDGGEPRRSSTALIQITVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGVNGKVTYKFRKINEKQSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDVGALLGRSKVIIMVEDVNDNRPEVTITSLFNPVLENSLPGTVIAFLNVHDQDSGKNGQVVCYTHDNLPFKLEKSIDNYYRLVTWKYLDREKVSTYNITVIASDLGAPPLSTETYIALTVADT 5szn A 2.94 BS01 CA A 1 E116 D173 E175 D209 N210 E110 D167 E169 D203 N204 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szn A 2.94 BS02 CA A 2 E116 R174 E175 D206 T207 D209 N210 D242 E110 R168 E169 D200 T201 D203 N204 D236 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szn A 2.94 BS03 CA A 3 N208 N210 D240 D242 N246 D295 N202 N204 D234 D236 N240 D289 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szn A 2.94 BS05 CA A 5 E225 E282 D311 V312 D314 N315 D347 E219 E276 D305 V306 D308 N309 D341 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szn A 2.94 BS06 CA A 6 E330 R384 E385 D416 I417 D419 D452 E324 R378 E379 D410 I411 D413 D446 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szn A 2.94 BS09 CA A 9 E9 E10 D63 E65 D100 N101 E7 E8 D57 E59 D94 N95 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szn A 2.94 BS10 CA A 10 E9 E65 D97 I98 D100 D133 E7 E59 D91 I92 D94 D127 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szn A 2.94 BS13 CA A 13 E435 D493 Y494 E495 D526 D529 E429 D487 Y488 E489 D520 D523 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szn A 2.94 BS14 CA A 14 E435 D493 D529 E429 D487 D523 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szn A 2.94 BS15 CA A 15 S326 T411 S320 T405 Q91XX9 IRYSVPEETEKGYIVGNISKDLGLEPERGVRIISKGKTQLFSLSPRSGSLVTAGRIDREELCAQSATCLLNFKVLVEDRVKLYGVEVEVVDINDNAPKFEAENLFVKISEIAAPGARYPLPEAVDPDVGINSLQSYQLSPNRHFSLHLQTGDDGTINPELVLERTLDREEEPTHHLVLTAYDGGNPRRSSTALIQVTVLDTNDNAPVFDQPVYRVKVLENVAPGTLLLTVRASDPDEGANGKVTYKFRKINEKHSLLFHLHENTGEMTVAKNLDYEECSLYEMEIQAEDGGGLKGRTKVVVMVEDVNDNRPEVTITSLFSPVREDAPPGTVILLFNAHDQDSGKNGQVVCSIQENPSFKLENSVDDYYRLLTAQILDREKASEYNITVTATDRGTPSMSTEVHITLYVADINDNPPAFSQTSYSVYLPENNPRGTSIFSVSAHDPDDEENAKVTYSLVENTIQGAPLSSYVSINSDTGVLYALQSFDYEQFQNLQMQVKASDNGHPPLSSNVSLSVFLLDQND 5szo A 3.61 BS01 CA A 1 E9 E10 D61 E63 D98 H99 E8 E9 D60 E62 D97 H98 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADV 5szo A 3.61 BS02 CA A 2 E9 E63 D95 V96 D98 H99 D131 E8 E62 D94 V95 D97 H98 D130 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADV 5szo A 3.61 BS03 CA A 3 N97 H99 P101 D129 D131 N135 D186 N96 H98 P100 D128 D130 N134 D185 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADV 5szo A 3.61 BS04 CA A 4 E114 D171 E173 D207 N208 E113 D170 E172 D206 N207 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADV 5szo A 3.61 BS05 CA A 5 E114 E173 D204 A205 D207 D240 E113 E172 D203 A204 D206 D239 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADV 5szo A 3.61 BS06 CA A 6 N206 N208 D238 D240 N244 D291 L295 N205 N207 D237 D239 N243 D290 L294 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADV 5szo A 3.61 BS08 CA A 8 E223 E278 D307 E308 D310 N311 D343 E222 E277 D306 E307 D309 N310 D342 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADV 5szo A 3.61 BS09 CA A 9 N309 N311 D341 D343 N347 D394 N308 N310 D340 D342 N346 D393 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADV 5szp A 3.10 BS02 CA A 2 E9 R62 E63 D95 V96 D98 H99 D131 E8 R61 E62 D94 V95 D97 H98 D130 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNV 5szp A 3.10 BS05 CA A 5 E114 R172 E173 D204 A205 D207 D240 E113 R171 E172 D203 A204 D206 D239 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNV 5szp A 3.10 BS07 CA A 7 E223 D276 E278 D310 E222 D275 E277 D309 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNV 5szp A 3.10 BS08 CA A 8 E223 E278 D307 E308 D310 D343 E222 E277 D306 E307 D309 D342 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNV 5szp A 3.10 BS10 TMO A 1 R121 E163 R120 E162 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNV 5szp B 3.10 BS02 CA B 2 E9 E63 D95 V96 D98 D131 E8 E62 D94 V95 D97 D130 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNV 5szp B 3.10 BS03 CA B 3 N97 H99 D129 D131 N135 D186 N96 H98 D128 D130 N134 D185 Q91XX3 PVRYSIPEELDRGSVVGKLAKDLGLSVLEVSARKLRVSAEKLHFSVDSESGDLLVKDRIDREQICKGRRKCELQLEAVLENPLNIFHVVVEIEDVNDHAPQFPKDEINLEISESDSPGARTILESAKDLDIGMNSLSKYQLSPNDYFLLLVKDNPDGSKYPELELQKMLDREAESTHHLMLTAVDGGDPPRTGTTQLRIRVVDANDNRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNV 5szr A 2.30 BS01 CA A 1 E223 D278 E280 D312 E15 D65 E67 D99 Q91XX7 PPMFSQDVFSVTLREDVPPGFSVLQVTATDQAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADS 5szr A 2.30 BS02 CA A 2 E223 E280 D309 E310 D312 D345 E15 E67 D96 E97 D99 D132 Q91XX7 PPMFSQDVFSVTLREDVPPGFSVLQVTATDQAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADS 5szr A 2.30 BS03 CA A 3 N311 C313 D343 D345 N349 D396 N98 C100 D130 D132 N136 D183 Q91XX7 PPMFSQDVFSVTLREDVPPGFSVLQVTATDQAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADS 5szr A 2.30 BS05 CA A 5 E328 E383 D414 V415 D417 N418 D450 E115 E170 D201 V202 D204 N205 D237 Q91XX7 PPMFSQDVFSVTLREDVPPGFSVLQVTATDQAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADS 5szr A 2.30 BS06 CA A 6 N416 N418 D448 D450 N454 D506 N203 N205 D235 D237 N241 D293 Q91XX7 PPMFSQDVFSVTLREDVPPGFSVLQVTATDQAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADS 5szr A 2.30 BS08 CA A 8 E433 E493 D524 R525 D527 N528 D567 E220 E280 D311 R312 D314 N315 D354 Q91XX7 PPMFSQDVFSVTLREDVPPGFSVLQVTATDQAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADS 5szr C 2.30 BS08 CA C 8 E433 E493 D524 R525 D527 D567 E211 E271 D302 R303 D305 D345 Q91XX7 PMFSQDVFSVTLREDVPPGFSVLQVTATDEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADS 5t0g A 4.40 BS01 ATP A 1 D176 G178 P218 G219 T220 G221 K222 T223 G382 A383 R386 D104 G106 P146 G147 T148 G149 K150 T151 G310 A311 R314 P35998 APPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN 5t0g A 4.40 BS02 ATP F 1 D307 M332 D235 M260 P35998 APPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN 5t0g B 4.40 BS01 ATP A 1 D317 P344 D225 P252 P62191 EEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEG 5t0g B 4.40 BS02 ATP B 1 D186 I187 G188 G229 T230 K232 T233 I364 H368 G392 A393 D94 I95 G96 G137 T138 K140 T141 I272 H276 G300 A301 P62191 EEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEG 5t0g D 4.40 BS01 ATP D 1 I167 P207 C210 G211 K212 T213 M214 E266 I344 N376 S377 I129 P169 C172 G173 K174 T175 M176 E228 I306 N338 S339 P43686 DLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 5t0g E 4.40 BS01 ATP D 1 D265 R291 R294 D229 R255 R258 A0A087X2I1 TKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV 5t0g E 4.40 BS02 ATP E 1 I135 P175 T178 G179 K180 T181 L182 I312 A341 R344 I99 P139 T142 G143 K144 T145 L146 I276 A305 R308 A0A087X2I1 TKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV 5t0g F 4.40 BS01 ATP E 1 D318 A341 R344 R347 D245 A268 R271 R274 P17980 THELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA 5t0g F 4.40 BS02 ATP F 1 I188 L191 P229 G230 T231 G232 K233 T234 L235 D286 N333 I365 H369 G393 A394 K397 I115 L118 P156 G157 T158 G159 K160 T161 L162 D213 N260 I292 H296 G320 A321 K324 P17980 THELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA 5t0g C 4.40 BS01 ATP B 1 L274 N278 P308 R310 L264 N268 P298 R300 P62195 LEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKD 5t0g C 4.40 BS02 ATP C 1 I151 G152 P192 T194 G195 K196 T197 L198 E250 I328 H332 G356 V359 K360 I141 G142 P182 T184 G185 K186 T187 L188 E240 I318 H322 G346 V349 K350 P62195 LEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKD 5t0g c 4.40 BS01 ZN c 1 H113 H115 S123 D126 H90 H92 S100 D103 3.4.19.- O00487 AVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 5t0h A 6.80 BS01 ADP A 1 D176 V177 G178 C180 P218 G219 T220 G221 G382 R386 D104 V105 G106 C108 P146 G147 T148 G149 G310 R314 P35998 APPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN 5t0h A 6.80 BS02 ADP F 1 D307 G335 D235 G263 P35998 APPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN 5t0h B 6.80 BS02 ADP B 1 D186 I187 G229 T230 G231 K232 T233 I364 I367 H368 G392 A393 K396 D94 I95 G137 T138 G139 K140 T141 I272 I275 H276 G300 A301 K304 P62191 EEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEG 5t0h C 6.80 BS01 ADP C 1 I151 G152 G193 T194 G195 K196 T197 L198 E250 I328 G356 V359 K360 I141 G142 G183 T184 G185 K186 T187 L188 E240 I318 G346 V349 K350 P62195 LEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKD 5t0h D 6.80 BS01 ADP D 1 I167 M170 P207 C210 G211 K212 T213 M214 E266 N376 S377 I129 M132 P169 C172 G173 K174 T175 M176 E228 N338 S339 P43686 DLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 5t0h E 6.80 BS01 ADP D 1 D265 R291 P292 G293 R294 D229 R255 P256 G257 R258 A0A087X2I1 TKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV 5t0h E 6.80 BS02 ADP E 1 P175 T178 G179 K180 T181 L182 I312 H316 G340 A341 P139 T142 G143 K144 T145 L146 I276 H280 G304 A305 A0A087X2I1 TKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV 5t0h F 6.80 BS02 ADP F 1 I188 G227 P228 P229 T231 G232 K233 T234 L235 N333 I365 H369 G393 A394 K397 I115 G154 P155 P156 T158 G159 K160 T161 L162 N260 I292 H296 G320 A321 K324 P17980 THELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA 5t0h V 6.80 BS01 III e 1 L67 T71 K209 T249 E284 R287 P317 H319 T320 A321 F324 K325 L50 T54 K192 T232 E267 R270 P300 H302 T303 A304 F307 K308 O43242 PPGGGEQEPPPPPAPQDVEMKEEAATGGGSTGEADGKTAAAAAEHSQRELDTVTLEDIKEHVKQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVQGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASTPLLPEVEAYLQLLVVIFMMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQADGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFP 5t0h Y 6.80 BS01 III e 2 S269 F272 Q273 A276 E279 Q280 K283 Y292 V296 R300 V325 F329 E333 R336 F337 A340 S258 F261 Q262 A265 E268 Q269 K272 Y281 V285 R289 V314 F318 E322 R325 F326 A329 Q15008 PKNPDLRIAQLRFLLSLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 5t0h c 6.80 BS01 ZN c 1 H113 H115 D126 H90 H92 D103 3.4.19.- O00487 AVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 5t0i A 8.00 BS01 ATP A 1 D176 G178 P218 G219 T220 G221 K222 T223 T321 N322 T381 G382 A383 D104 G106 P146 G147 T148 G149 K150 T151 T249 N250 T309 G310 A311 P35998 APPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN 5t0i B 8.00 BS01 ATP A 1 D317 A340 R343 P344 D225 A248 R251 P252 P62191 EEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 5t0i D 8.00 BS01 ATP D 1 C210 K212 T213 M214 I344 T347 N376 Q380 C172 K174 T175 M176 I306 T309 N338 Q342 P43686 DLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 5t0i E 8.00 BS01 ATP E 1 I135 P175 T178 G179 K180 T181 L182 I312 I315 H316 N339 G340 A341 I99 P139 T142 G143 K144 T145 L146 I276 I279 H280 N303 G304 A305 A0A087X2I1 TKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV 5t0i F 8.00 BS02 ATP F 1 I188 L191 G230 T231 G232 K233 T234 L235 D286 N333 I365 H369 G393 A394 K397 I115 L118 G157 T158 G159 K160 T161 L162 D213 N260 I292 H296 G320 A321 K324 P17980 THELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA 5t0i c 8.00 BS01 ZN c 1 H115 S123 D126 H92 S100 D103 3.4.19.- O00487 AVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 5t0j A 8.00 BS01 ATP A 1 V172 D176 V177 P218 G219 T220 G221 K222 I354 G382 R386 V100 D104 V105 P146 G147 T148 G149 K150 I282 G310 R314 P35998 APPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN 5t0j A 8.00 BS02 ATP F 1 M332 G335 M260 G263 P35998 APPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN 5t0j D 8.00 BS01 ATP D 1 D166 I167 P207 C210 G211 K212 T213 M214 I344 N376 S377 Q380 D128 I129 P169 C172 G173 K174 T175 M176 I306 N338 S339 Q342 P43686 DLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 5t0j E 8.00 BS01 ATP D 1 D265 R294 D229 R258 A0A087X2I1 TKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV 5t0j E 8.00 BS02 ATP E 1 P175 T178 G179 K180 T181 L182 I312 H316 N339 G340 A341 R344 P139 T142 G143 K144 T145 L146 I276 H280 N303 G304 A305 R308 A0A087X2I1 TKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV 5t0j F 8.00 BS01 ATP E 1 D318 A341 L343 R344 R347 D245 A268 L270 R271 R274 P17980 THELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA 5t0j F 8.00 BS02 ATP F 1 D187 I188 P229 G230 T231 G232 K233 T234 L235 D286 E287 N333 I365 H369 G393 A394 K397 D114 I115 P156 G157 T158 G159 K160 T161 L162 D213 E214 N260 I292 H296 G320 A321 K324 P17980 THELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA 5t5i A 1.90 BS01 ZN A 1 K178 H231 H271 K178 H231 H271 MEYIIKNGFVYCPLNGVDGEKMDICVKDGKIVESVSDSAKVIDASGKIVMPGGVDPHSHIAGAKVNVGRMYRPEDSKRDAEKFKGGRAGSGFSVPSTFMTGYRYAQMGYTTAMEAAMPPLLARHTHEEFHDTPIIDHAAYPLFGNNWFVMEYLKEGDVDACAAYASWLLRATKGYTIKIVNPAGTEAWGWGGNVHGIYDPAPYFDITPAEIIKGLAEVNEKLQLPHSIHLHCNDLGHPGNYETTLASFDVPKNIKPNPATGSRDTVLYATHVQFHSYGGTTWRDFVSEAPKIADYVNKNDHIVIDVGQITLDETTTMTADGPMEYDLHSLNGLKWANCDVELETGSGVVPFIYSARAPVPAVQWAIGMELFLLIDNPEKVCLTTDSPNAGPFTRYPRVIAWLMSNKYRMNLIEGELHKWAQRKSTVATIDREYTFSEIAQITRATSAKVLGLSDTKGHLGVGADADIAVYDINPETVDPSAEYMAIEEAFSRAACVLKDGEIVVKDGEVVASPHGRTYWVDTQVDESIYSEVLANVESKFKQYYSVNFANYPVQDDYLPKSAPVKGVML 5t5i A 1.90 BS02 ZN A 2 H57 H59 K178 D385 H57 H59 K178 D385 MEYIIKNGFVYCPLNGVDGEKMDICVKDGKIVESVSDSAKVIDASGKIVMPGGVDPHSHIAGAKVNVGRMYRPEDSKRDAEKFKGGRAGSGFSVPSTFMTGYRYAQMGYTTAMEAAMPPLLARHTHEEFHDTPIIDHAAYPLFGNNWFVMEYLKEGDVDACAAYASWLLRATKGYTIKIVNPAGTEAWGWGGNVHGIYDPAPYFDITPAEIIKGLAEVNEKLQLPHSIHLHCNDLGHPGNYETTLASFDVPKNIKPNPATGSRDTVLYATHVQFHSYGGTTWRDFVSEAPKIADYVNKNDHIVIDVGQITLDETTTMTADGPMEYDLHSLNGLKWANCDVELETGSGVVPFIYSARAPVPAVQWAIGMELFLLIDNPEKVCLTTDSPNAGPFTRYPRVIAWLMSNKYRMNLIEGELHKWAQRKSTVATIDREYTFSEIAQITRATSAKVLGLSDTKGHLGVGADADIAVYDINPETVDPSAEYMAIEEAFSRAACVLKDGEIVVKDGEVVASPHGRTYWVDTQVDESIYSEVLANVESKFKQYYSVNFANYPVQDDYLPKSAPVKGVML 5t5i A 1.90 BS03 MG A 1 V340 T344 V340 T344 MEYIIKNGFVYCPLNGVDGEKMDICVKDGKIVESVSDSAKVIDASGKIVMPGGVDPHSHIAGAKVNVGRMYRPEDSKRDAEKFKGGRAGSGFSVPSTFMTGYRYAQMGYTTAMEAAMPPLLARHTHEEFHDTPIIDHAAYPLFGNNWFVMEYLKEGDVDACAAYASWLLRATKGYTIKIVNPAGTEAWGWGGNVHGIYDPAPYFDITPAEIIKGLAEVNEKLQLPHSIHLHCNDLGHPGNYETTLASFDVPKNIKPNPATGSRDTVLYATHVQFHSYGGTTWRDFVSEAPKIADYVNKNDHIVIDVGQITLDETTTMTADGPMEYDLHSLNGLKWANCDVELETGSGVVPFIYSARAPVPAVQWAIGMELFLLIDNPEKVCLTTDSPNAGPFTRYPRVIAWLMSNKYRMNLIEGELHKWAQRKSTVATIDREYTFSEIAQITRATSAKVLGLSDTKGHLGVGADADIAVYDINPETVDPSAEYMAIEEAFSRAACVLKDGEIVVKDGEVVASPHGRTYWVDTQVDESIYSEVLANVESKFKQYYSVNFANYPVQDDYLPKSAPVKGVML 5t5i B 1.90 BS01 SF4 B 1 C9 F11 C12 T14 L15 C16 A34 C35 G38 P158 R159 C9 F11 C12 T14 L15 C16 A34 C35 G38 P158 R159 MEYVKNVVCPFCGTLCDDIICKVEGNEIVGTINACRIGHSKFVHAEGAMRYKKPLIRKNGEFVEVSYDEAIDKAAKILAESKRPLMYGWSCTECEAQAVGVELAEEAGAVIDNTASVCHGPSVLALQDVGYPICTFGEVKNRADVVVYWGCNPMHAHPRHMSRNVFARGFFRERGRSDRTLIVVDPRKTDSAKLADIHLQLDFDRDYELLDAMRACLLGHEILYDEVAGVPREQIEEAVEVLKNAQFGILFFGMGITHSRGKHRNIDTAIMMVQDLNDYAKWTLIPMRGHYNVTGFNQVCTWESGYPYCVDFSGGEPRYNPGETGANDLLQNREADAMMVIASDPGAHFPQRALERMAEIPVIAIEPHRTPTTEMADIIIPPAIVGMEAEGTAYRMEGVPIRMKKVVDSDLLSDREILERLLEKVREYKA 5t5i B 1.90 BS02 MGD B 1 K41 C91 T114 V117 C118 M254 H258 H290 A342 S343 D344 H348 I365 E366 P367 H368 T370 P382 I384 V385 D414 K41 C91 T114 V117 C118 M254 H258 H290 A342 S343 D344 H348 I365 E366 P367 H368 T370 P382 I384 V385 D414 MEYVKNVVCPFCGTLCDDIICKVEGNEIVGTINACRIGHSKFVHAEGAMRYKKPLIRKNGEFVEVSYDEAIDKAAKILAESKRPLMYGWSCTECEAQAVGVELAEEAGAVIDNTASVCHGPSVLALQDVGYPICTFGEVKNRADVVVYWGCNPMHAHPRHMSRNVFARGFFRERGRSDRTLIVVDPRKTDSAKLADIHLQLDFDRDYELLDAMRACLLGHEILYDEVAGVPREQIEEAVEVLKNAQFGILFFGMGITHSRGKHRNIDTAIMMVQDLNDYAKWTLIPMRGHYNVTGFNQVCTWESGYPYCVDFSGGEPRYNPGETGANDLLQNREADAMMVIASDPGAHFPQRALERMAEIPVIAIEPHRTPTTEMADIIIPPAIVGMEAEGTAYRMEGVPIRMKKVVDSDLLSDREILERLLEKVREYKA 5t5i B 1.90 BS03 MGD B 2 F11 I37 C118 G150 C151 N152 H155 A156 H157 V184 D185 P186 R187 T189 F203 D204 D206 G253 M254 G255 S259 G289 H290 F11 I37 C118 G150 C151 N152 H155 A156 H157 V184 D185 P186 R187 T189 F203 D204 D206 G253 M254 G255 S259 G289 H290 MEYVKNVVCPFCGTLCDDIICKVEGNEIVGTINACRIGHSKFVHAEGAMRYKKPLIRKNGEFVEVSYDEAIDKAAKILAESKRPLMYGWSCTECEAQAVGVELAEEAGAVIDNTASVCHGPSVLALQDVGYPICTFGEVKNRADVVVYWGCNPMHAHPRHMSRNVFARGFFRERGRSDRTLIVVDPRKTDSAKLADIHLQLDFDRDYELLDAMRACLLGHEILYDEVAGVPREQIEEAVEVLKNAQFGILFFGMGITHSRGKHRNIDTAIMMVQDLNDYAKWTLIPMRGHYNVTGFNQVCTWESGYPYCVDFSGGEPRYNPGETGANDLLQNREADAMMVIASDPGAHFPQRALERMAEIPVIAIEPHRTPTTEMADIIIPPAIVGMEAEGTAYRMEGVPIRMKKVVDSDLLSDREILERLLEKVREYKA 5t5i C 1.90 BS01 CA B 1 S139 Y140 G142 D143 E164 Y165 S138 Y139 G141 D142 E163 Y164 1.2.99.5 SEIILTPKEQPEVPLEAPNIKPDVFAGKSIEEIKNIQIMHGNEVVKLGDFFEVSGEPADAPEDIKIIIDGDVYNTKRIGQEMTAGEIIVRGNVNMYVGAGMKGGKITVEGNAGSWAGQDMRGGEIEILGDAGDYVGSSYRGDWRGMSGGTITVHGNADNEIGEYMNGGKIIIKGDVNIMPGIHMNNGLIIIEGNVVARAGGEMAGGTIVVKGMMQEFLAGFKYLGVEKDIEVDGEELPGAFYKFEGDHAIKGAKGIVYAAVGCNGHIAP 5t5i D 1.90 BS01 MGD B 1 T7 R9 K21 M80 N85 F100 K101 T7 R9 K21 M80 N85 F100 K101 MRVILNTGRTIWQGQAIESGKDLKMYVDAAAIIQMNPEMMKQLGIAEGDNVKVISEYGDVVVKAVEAKEPLPEGMVYIPMGPWANRVIRPYTDSTATPSFKNIPVEIIPTDEEVLDMPTLMKVYGKVGQI 5t5i D 1.90 BS02 MGD B 3 N6 G8 R9 T10 Q13 G14 I17 M80 K101 N102 N6 G8 R9 T10 Q13 G14 I17 M80 K101 N102 MRVILNTGRTIWQGQAIESGKDLKMYVDAAAIIQMNPEMMKQLGIAEGDNVKVISEYGDVVVKAVEAKEPLPEGMVYIPMGPWANRVIRPYTDSTATPSFKNIPVEIIPTDEEVLDMPTLMKVYGKVGQI 5t5i F 1.90 BS01 SF4 F 1 L264 C281 P282 C283 V285 C308 I309 Y310 C311 G312 C314 L250 C267 P268 C269 V271 C294 I295 Y296 C297 G298 C300 TTEVIEGKNITVERTNRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5i F 1.90 BS02 SF4 F 2 C271 Q272 A273 C274 E275 C277 L301 C318 V320 A322 I323 C257 Q258 A259 C260 E261 C263 L287 C304 V306 A308 I309 TTEVIEGKNITVERTNRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5i F 1.90 BS03 SF4 F 3 L24 C41 I46 C71 V72 L73 C74 G75 C77 L19 C36 I41 C66 V67 L68 C69 G70 C72 TTEVIEGKNITVERTNRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5i F 1.90 BS04 SF4 F 4 F26 C31 A32 V33 C34 G35 C37 C81 F83 A85 L86 F21 C26 A27 V28 C29 G30 C32 C76 F78 A80 L81 TTEVIEGKNITVERTNRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5i F 1.90 BS05 SF4 F 5 C125 P126 I130 I234 C239 V240 N241 C242 G243 W244 C245 V256 C120 P121 I125 I220 C225 V226 N227 C228 G229 W230 C231 V242 TTEVIEGKNITVERTNRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5i F 1.90 BS06 SF4 F 6 I110 C115 I116 Q117 C118 K119 C121 I132 C249 P250 V251 A253 I105 C110 I111 Q112 C113 K114 C116 I127 C235 P236 V237 A239 TTEVIEGKNITVERTNRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5i F 1.90 BS07 SF4 F 7 C154 I155 Y156 C157 G158 C160 I171 I187 C204 P205 V206 I209 C149 I150 Y151 C152 G153 C155 I166 I182 C199 P200 V201 I204 TTEVIEGKNITVERTNRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5i F 1.90 BS08 SF4 F 8 I147 C164 P165 V166 I169 C194 V195 H196 C197 G198 C200 I142 C159 P160 V161 I164 C189 V190 H191 C192 G193 C195 TTEVIEGKNITVERTNRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5i G 1.90 BS01 SF4 G 1 C12 H13 G14 C15 G16 N17 C18 V53 C71 V73 A75 I76 C11 H12 G13 C14 G15 N16 C17 V52 C70 V72 A74 I75 AIGLKAYPELCHGCGNCVIACPVNALRSPEVAGGKGPTDDVEIIMIVEDGVVNIKNPDLCGKCGTCVESCPVDAIRLEEL 5t5i G 1.90 BS02 SF4 G 2 L5 C22 P23 V24 I45 M46 C61 G62 K63 C64 G65 T66 C67 L4 C21 P22 V23 I44 M45 C60 G61 K62 C63 G64 T65 C66 AIGLKAYPELCHGCGNCVIACPVNALRSPEVAGGKGPTDDVEIIMIVEDGVVNIKNPDLCGKCGTCVESCPVDAIRLEEL 5t5i K 1.90 BS01 CA J 1 S139 Y140 R141 G142 D143 E164 Y165 S138 Y139 R140 G141 D142 E163 Y164 1.2.99.5 SEIILTPKEQPEVPLEAPNIKPDVFAGKSIEEIKNIQIMHGNEVVKLGDFFEVSGEPADAPEDIKIIIDGDVYNTKRIGQEMTAGEIIVRGNVNMYVGAGMKGGKITVEGNAGSWAGQDMRGGEIEILGDAGDYVGSSYRGDWRGMSGGTITVHGNADNEIGEYMNGGKIIIKGDVNIMPGIHMNNGLIIIEGNVVARAGGEMAGGTIVVKGMMQEFLAGFKYLGVEKDIEVDGEELPGAFYKFEGDHAIKGAKGIVYAAVGCNGHIAP 5t5i L 1.90 BS02 MGD J 3 T7 G8 R9 K21 M80 N85 F100 K101 T7 G8 R9 K21 M80 N85 F100 K101 MRVILNTGRTIWQGQAIESGKDLKMYVDAAAIIQMNPEMMKQLGIAEGDNVKVISEYGDVVVKAVEAKEPLPEGMVYIPMGPWANRVIRPYTDSTATPSFKNIPVEIIPTDEEVLDMPTLMKVYGKVGQI 5t5i N 1.90 BS01 SF4 N 1 L264 C281 P282 C283 V285 L286 C308 I309 Y310 C311 G312 A313 C314 L244 C261 P262 C263 V265 L266 C288 I289 Y290 C291 G292 A293 C294 GKNITVERTGEENRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5i N 1.90 BS07 SF4 N 7 L24 C41 V43 I46 C71 V72 L73 C74 G75 C77 L16 C33 V35 I38 C63 V64 L65 C66 G67 C69 GKNITVERTGEENRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5m A 2.50 BS04 MG A 2 R69 R72 S76 R69 R72 S76 1.2.99.5 MEYIIKNGFVYCPLNGVDGEKMDICVKDGKIVESVSDSAKVIDASGKIVMPGGVDPHSHIAGAKVNVGRMYRPEDSKRDAEKFKGGRAGSGFSVPSTFMTGYRYAQMGYTTAMEAAMPPLLARHTHEEFHDTPIIDHAAYPLFGNNWFVMEYLKEGDVDACAAYASWLLRATKGYTIKIVNPAGTEAWGWGGNVHGIYDPAPYFDITPAEIIKGLAEVNEKLQLPHSIHLHCNDLGHPGNYETTLASFDVPKNIKPNPATGSRDTVLYATHVQFHSYGGTTWRDFVSEAPKIADYVNKNDHIVIDVGQITLDETTTMTADGPMEYDLHSLNGLKWANCDVELETGSGVVPFIYSARAPVPAVQWAIGMELFLLIDNPEKVCLTTDSPNAGPFTRYPRVIAWLMSNKYRMNLIEGELHKWAQRKSTVATIDREYTFSEIAQITRATSAKVLGLSDTKGHLGVGADADIAVYDINPETVDPSAEYMAIEEAFSRAACVLKDGEIVVKDGEVVASPHGRTYWVDTQVDESIYSEVLANVESKFKQYYSVNFANYPVQDDYLPKSAPVKGVML 5t5m B 2.50 BS01 SF4 B 1 C9 F11 C12 T14 C16 C35 G38 P158 R159 C9 F11 C12 T14 C16 C35 G38 P158 R159 1.2.99.5 MEYVKNVVCPFCGTLCDDIICKVEGNEIVGTINACRIGHSKFVHAEGAMRYKKPLIRKNGEFVEVSYDEAIDKAAKILAESKRPLMYGWSCTECEAQAVGVELAEEAGAVIDNTASVCHGPSVLALQDVGYPICTFGEVKNRADVVVYWGCNPMHAHPRHMSRNVFARGFFRERGRSDRTLIVVDPRKTDSAKLADIHLQLDFDRDYELLDAMRACLLGHEILYDEVAGVPREQIEEAVEVLKNAQFGILFFGMGITHSRGKHRNIDTAIMMVQDLNDYAKWTLIPMRGHYNVTGFNQVCTWESGYPYCVDFSGGEPRYNPGETGANDLLQNREADAMMVIASDPGAHFPQRALERMAEIPVIAIEPHRTPTTEMADIIIPPAIVGMEAEGTAYRMEGVPIRMKKVVDSDLLSDREILERLLEKVREYK 5t5m C 2.50 BS01 MG C 1 S139 Y140 G142 D143 Y165 S138 Y139 G141 D142 Y164 1.2.99.5 SEIILTPKEQPEVPLEAPNIKPDVFAGKSIEEIKNIQIMHGNEVVKLGDFFEVSGEPADAPEDIKIIIDGDVYNTKRIGQEMTAGEIIVRGNVNMYVGAGMKGGKITVEGNAGSWAGQDMRGGEIEILGDAGDYVGSSYRGDWRGMSGGTITVHGNADNEIGEYMNGGKIIIKGDVNIMPGIHMNNGLIIIEGNVVARAGGEMAGGTIVVKGMMQEFLAGFKYLGVEKDIEVDGEELPGAFYKFEGDHAIKGAKGIVYAAVGCNGHIAP 5t5m F 2.50 BS01 SF4 F 1 C154 I155 Y156 C157 G158 C160 I187 C204 P205 I209 C153 I154 Y155 C156 G157 C159 I186 C203 P204 I208 ETTEVIEGKNITVERTGEENRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRYEIKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5m F 2.50 BS05 SF4 F 5 L24 C41 P42 V43 A45 I46 C71 V72 L73 C74 G75 M76 C77 L23 C40 P41 V42 A44 I45 C70 V71 L72 C73 G74 M75 C76 ETTEVIEGKNITVERTGEENRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRYEIKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5m F 2.50 BS06 SF4 F 6 C31 V33 C34 G35 C37 C81 F83 A85 L86 C30 V32 C33 G34 C36 C80 F82 A84 L85 ETTEVIEGKNITVERTGEENRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRYEIKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5m F 2.50 BS07 SF4 F 7 C125 I130 C239 V240 N241 C242 G243 C245 V256 C124 I129 C232 V233 N234 C235 G236 C238 V249 ETTEVIEGKNITVERTGEENRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRYEIKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5m F 2.50 BS08 SF4 F 8 C115 I116 Q117 C118 K119 C121 C249 P250 V251 A253 C114 I115 Q116 C117 K118 C120 C242 P243 V244 A246 ETTEVIEGKNITVERTGEENRRLIFQDCLCAVCGLCGEICPVSAIEVNPTGAMVRTEQEKSKIAIDENKCVLCGMCSSICPFQALDLQIDGTSIKELAEYPKIIKSAEIDDETCIQCKACETACPQDAITITRELPERKDLVTGEIEIDKDTCIYCGMCEEMCPVDAIEIDHQTPSSASPVVATDIRVDEDKCVHCGICKRICPVDAIMQVCRYEIKTPEVTGTSYIDPELCVNCGWCQEICPVDAATVTKPFEGELIIDQDTCQACETCVMVCPCNVLSFPKPEKPGEKTTKLHKDERFCIYCGACERSCPVTAITVKRNRINTTPIRSKAWKNAFDSLLK 5t5m G 2.50 BS02 SF4 G 2 L5 C22 I45 M46 C61 G62 K63 C64 G65 T66 C67 L4 C21 I44 M45 C60 G61 K62 C63 G64 T65 C66 AIGLKAYPELCHGCGNCVIACPVNALRSPEVAGGKGPTDDVEIIMIVEDGVVNIKNPDLCGKCGTCVESCPVDAIRLEEL 5t9t A 3.50 BS01 CA A 1 E9 E10 D61 E63 D98 E9 E10 D61 E63 D98 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t A 3.50 BS02 CA A 2 E9 E63 D95 V96 D98 D131 E9 E63 D95 V96 D98 D131 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t A 3.50 BS03 CA A 3 N97 N99 P101 D129 D131 N135 D186 N97 N99 P101 D129 D131 N135 D186 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t A 3.50 BS04 CA A 4 E114 D171 E173 D207 E114 D171 E173 D207 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t A 3.50 BS05 CA A 5 E114 E173 D204 I205 D207 D240 E114 E173 D204 I205 D207 D240 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t A 3.50 BS06 CA A 6 N206 N208 D238 D240 N244 D293 N206 N208 D238 D240 N244 D293 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t A 3.50 BS08 CA A 8 E223 E280 D309 E310 D312 D345 E223 E280 D309 E310 D312 D345 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t A 3.50 BS09 CA A 9 N311 C313 P315 D343 D345 N349 D396 N311 C313 P315 D343 D345 N349 D396 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t A 3.50 BS10 CA A 10 E328 D381 E383 D417 N418 E328 D381 E383 D417 N418 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t A 3.50 BS11 CA A 11 E328 E383 D414 V415 D417 N418 D450 E328 E383 D414 V415 D417 N418 D450 Q8K486 DQIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRN 5t9t B 3.50 BS01 CA B 1 E9 E10 D61 E63 D98 N99 E8 E9 D60 E62 D97 N98 Q8K486 QIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRND 5t9t B 3.50 BS09 CA B 9 N311 C313 D343 D345 N349 D396 N310 C312 D342 D344 N348 D395 Q8K486 QIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRND 5t9t B 3.50 BS13 CA B 13 E433 E493 D524 R525 N526 D527 E432 E492 D523 R524 N525 D526 Q8K486 QIRYSIPEELAKNSIVGNLARDLGLSVQNLPTRKLRVSAEKDYFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVILQDVNDNAPLFKQSEVDLNIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGRKYPELILKRFLDREEHNFHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLREDVPPGFSVLQVTATDQDEGVNAEITYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETAKSYTLNVEAKDPGDLASHCSIQVKILDENDCVPEVIVTSVFTPLPEDSPLGTVIALIKTRDRDSGENGDVYCHVLGNEGFVLKSSSKNYYKLVTDRTLDREAIPEYNVTIVAADRGKPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIASDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRVLVGDRND 5tca A 3.15 BS01 J55 A 1 H39 L40 C41 H56 C57 W143 G144 R152 C194 K195 G196 S198 V212 T213 S214 G215 S216 R217 C219 H24 L25 C26 H41 C42 W128 G129 R137 C179 K180 G181 S183 V197 T198 S199 G200 S201 R202 C204 3.4.21.46 P00746 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 5tca C 3.15 BS02 J55 C 2 G18 R20 G135 L137 H158 V159 L160 P162 R191 G3 R5 G120 L122 H143 V144 L145 P147 R176 3.4.21.46 P00746 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 5tca D 3.15 BS02 J55 D 2 R20 G135 L137 H158 V159 L160 P162 E187 R191 R5 G120 L122 H143 V144 L145 P147 E172 R176 3.4.21.46 P00746 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 5tcc A 3.37 BS01 J56 A 1 H39 L40 C41 H56 C57 W143 G144 R152 K195 G196 S198 T213 S214 G215 S216 R217 C219 H24 L25 C26 H41 C42 W128 G129 R137 K180 G181 S183 T198 S199 G200 S201 R202 C204 3.4.21.46 P00746 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 5tcc C 3.37 BS02 J56 C 2 R20 G135 L137 H158 V159 L160 P162 R191 R5 G120 L122 H143 V144 L145 P147 R176 3.4.21.46 P00746 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 5tcc D 3.37 BS01 J56 D 1 H39 L40 C41 H56 C57 E59 W143 G144 I145 R152 K195 G196 S198 T213 S214 G215 S216 R217 C219 H24 L25 C26 H41 C42 E44 W128 G129 I130 R137 K180 G181 S183 T198 S199 G200 S201 R202 C204 3.4.21.46 P00746 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 5tcc E 3.37 BS02 J56 E 2 G18 L137 L160 P162 E187 G3 L122 L145 P147 E172 3.4.21.46 P00746 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 5tdw A 1.70 BS01 III B 1 G14 F15 T16 I17 Q18 C19 D20 N23 W25 I36 P40 D41 Y43 G14 F15 T16 I17 Q18 C19 D20 N23 W25 I36 P40 D41 Y43 P36124 27697561 GIITCICDLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLCNSCDPREVDINLARKIQQERINVK 5tdw A 1.70 BS02 ZN A 1 C5 C7 H27 C30 C5 C7 H27 C30 P36124 27697561 GIITCICDLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLCNSCDPREVDINLARKIQQERINVK 5tdw A 1.70 BS03 ZN A 2 C19 C22 C45 C48 C19 C22 C45 C48 P36124 27697561 GIITCICDLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLCNSCDPREVDINLARKIQQERINVK 5tef A 1.95 BS01 GTG A 1 Y474 T540 E541 L580 N582 K641 T643 Y660 R684 Y440 T498 E499 L538 N540 K599 T601 Y618 R642 Q8TEQ6 QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGECYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHQGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQ 5tf9 A 2.50 BS01 7AV A 1 L252 R255 F265 E268 L272 V281 F283 L299 T301 I345 D368 L369 G370 A372 L43 R46 F56 E59 L63 V72 F74 L87 T89 I133 D156 L157 G158 A160 2.7.11.1 Q9H4A3 27712055 KAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEET 5tf9 A 2.50 BS02 ANP A 1 G228 G230 S231 K233 V235 A248 T301 E302 M304 K351 F356 G19 G21 S22 K24 V26 A39 T89 E90 M92 K139 F144 2.7.11.1 Q9H4A3 27712055 KAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEET 5tf9 A 2.50 BS03 MN A 1 N354 D368 N142 D156 2.7.11.1 Q9H4A3 27712055 KAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEET 5tf9 A 2.50 BS04 CA A 1 S423 C425 S202 C204 2.7.11.1 Q9H4A3 27712055 KAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEET 5tf9 B 2.50 BS01 7AV B 1 F265 E268 M271 L272 L275 V281 F283 L299 I345 D368 L369 G370 A372 F60 E63 M66 L67 L70 V76 F78 L94 I140 D163 L164 G165 A167 2.7.11.1 Q9H4A3 27712055 ELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQ 5tf9 B 2.50 BS02 ANP B 1 G228 R229 G230 S231 K233 E302 L303 M304 K351 D368 G23 R24 G25 S26 K28 E97 L98 M99 K146 D163 2.7.11.1 Q9H4A3 27712055 ELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQ 5tha A 1.80 BS01 GP3 A 1 Y474 T540 L580 N582 K641 Y660 Y442 T501 L541 N543 K602 Y621 Q8TEQ6 QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQSRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHQGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQG 5thx A 1.55 BS01 NAP A 1 A18 Y19 I69 T115 G143 V144 R145 Y146 K148 D149 S181 R182 R190 A223 M224 D227 A17 Y18 I68 T114 G142 V143 R144 Y145 K147 D148 S180 R181 R189 A222 M223 D226 A0A0M3GW31 AAFNTQKVLSVHHWTDAYFTFTCIRDESLRFENGQFVMVGLMADGKPLMRAYSVASANWEEHLEFFSIKVQDGPLTSRLQHLKVGDEVLISKKPTGTLVACDLNPGKHLYLLSTGTGIAPFLSITKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDLVKEKLIYYPIVSREEFEHRGRLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDDFGLTVSPKTGVRGDYLIERAFVDQ 5thx A 1.55 BS02 MG A 1 R26 R31 F32 N59 R25 R30 F31 N58 A0A0M3GW31 AAFNTQKVLSVHHWTDAYFTFTCIRDESLRFENGQFVMVGLMADGKPLMRAYSVASANWEEHLEFFSIKVQDGPLTSRLQHLKVGDEVLISKKPTGTLVACDLNPGKHLYLLSTGTGIAPFLSITKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDLVKEKLIYYPIVSREEFEHRGRLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDDFGLTVSPKTGVRGDYLIERAFVDQ 5thx A 1.55 BS03 FAD A 1 F37 R51 A52 Y53 S54 F67 S68 I69 V71 G74 P75 L76 T77 T117 A120 E252 R253 A254 F255 V256 D257 Q258 F36 R50 A51 Y52 S53 F66 S67 I68 V70 G73 P74 L75 T76 T116 A119 E251 R252 A253 F254 V255 D256 Q257 A0A0M3GW31 AAFNTQKVLSVHHWTDAYFTFTCIRDESLRFENGQFVMVGLMADGKPLMRAYSVASANWEEHLEFFSIKVQDGPLTSRLQHLKVGDEVLISKKPTGTLVACDLNPGKHLYLLSTGTGIAPFLSITKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDLVKEKLIYYPIVSREEFEHRGRLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDDFGLTVSPKTGVRGDYLIERAFVDQ 5thy A 2.09 BS01 SAH A 1 Y169 G205 A206 G207 G209 G210 T211 D230 I231 F235 L254 D255 I256 E257 A276 N277 V278 Y175 G211 A212 G213 G215 G216 T217 D236 I237 F241 L260 D261 I262 E263 A282 N283 V284 F4Y426 YFQSNALPPDFLLDPVEVSQQLAPSLTELVTLLDNARTSEIGTQLEELSVDYIVQGLLQMGWSYQPTESFDLDAAAQCLGVVPTQVRLFERLLQILAEVGILQSNQQQWQVQKTAQKVNPSKQSQSLLSQYPDEAATLTLLERCASQLSGVLRGEIDPVQLVFPQGDLTTATQLYKDSAVAKVMNTIVEKVIMKAMEKLPPSRGIRLLEIGAGTGGTTSYILPHLNPNQTEYIFTDIGALFTSKAQEKFQDYRFLGYQTLDIEVDPSSQGFESHRYDVIIAANVLHATTSLKQTLSHVRQLLAPGGILVLYEATTRSRWVDLIFGLLEGWWKFTDYELRPDYPLLNREQWKKVLSETGFTQVVTLPEVEGMAEALSQQTVIVAQAAS 5thy B 2.09 BS02 GDS B 1 E41 V44 D45 I95 K107 T108 Q110 V112 E36 V39 D40 I90 K102 T103 Q105 V107 F4Y426 LLDPVEVSQQLAPSLTELVTLLDNARTSEIGTQLEELSVDYIVQGLLQMGWSYQPTESFDLDAAAQCLGVVPTQVRLFERLLQILAEVGILQSNQQQWQVQKTAQKVNPSKQSQSLLSQYPDEAATLTLLERCASQLSGVLRGEIDPVQLVFPQGDLTTATQLYKDSAVAKVMNTIVEKVIMKAMEKLPPSRGIRLLEIGAGTGGTTSYILPHLNPNQTEYIFTDIGALFTSKAQEKFQDYRFLGYQTLDIEVDPSSQGFESHRYDVIIAANVLHATTSLKQTLSHVRQLLAPGGILVLYEATTRSRWVDLIFGLLEGWWKFTDYELRPDYPLLNREQWKKVLSETGFTQVVTLPEVEGMAEALSQQTVIVAQAAS 5thz B 2.10 BS01 SAH B 1 F157 T166 Y169 G205 A206 G207 G210 T211 D230 I231 F235 L254 D255 I256 E257 A276 N277 V278 F163 T172 Y175 G211 A212 G213 G216 T217 D236 I237 F241 L260 D261 I262 E263 A282 N283 V284 F4Y426 YFQSNALPPDFLLDPVEVSQQLAPSLTELVTLLDNARTSEIGTQLEELSVDYIVQGLLQMGWSYQPTESFDLDAAAQCLGVVPTQVRLFERLLQILAEVGILQSNQQQWQVQKTAQKVNPSKQSQSLLSQYPDEAATLTLLERCASQLSGVLRGEIDPVQLVFPQGDLTTATQLYKDSAVAKVMNTIVEKVIMKAMEKLPPSRGIRLLEIGAGTGGTTSYILPHLNPNQTEYIFTDIGALFTSKAQEKFQDYRFLGYQTLDIEVDPSSQGFESHRYDVIIAANVLHATTSLKQTLSHVRQLLAPGGILVLYEATTRSRWVDLIFGLLEGWWKFTDYELRPDYPLLNREQWKKVLSETGFTQVVTLPEVEGMAEALSQQTVIVAQAAS 5thz A 2.10 BS01 SAH A 1 T166 G205 A206 G207 T208 G210 T211 D230 I231 F235 L254 D255 I256 E257 A276 N277 V278 T161 G200 A201 G202 T203 G205 T206 D225 I226 F230 L249 D250 I251 E252 A271 N272 V273 F4Y426 LLDPVEVSQQLAPSLTELVTLLDNARTSEIGTQLEELSVDYIVQGLLQMGWSYQPTESFDLDAAAQCLGVVPTQVRLFERLLQILAEVGILQSNQQQWQVQKTAQKVNPSKQSQSLLSQYPDEAATLTLLERCASQLSGVLRGEIDPVQLVFPQGDLTTATQLYKDSAVAKVMNTIVEKVIMKAMEKLPPSRGIRLLEIGAGTGGTTSYILPHLNPNQTEYIFTDIGALFTSKAQEKFQDYRFLGYQTLDIEVDPSSQGFESHRYDVIIAANVLHATTSLKQTLSHVRQLLAPGGILVLYEATTRSRWVDLIFGLLEGWWKFTDYELRPDYPLLNREQWKKVLSETGFTQVVTLPEVEGMAEALSQQTVIVAQAAS 5tj9 A 2.60 BS01 7CY A 1 H53 T55 E57 T58 D137 E211 T212 K241 D245 H356 L401 L404 T408 G409 H410 M415 F419 H52 T54 E56 T57 D136 E210 T211 K240 D244 H355 L400 L403 T407 G408 H409 M414 F418 3.3.1.1 Q5CPH1 KMESRIKDISLAEFGLQDMEIAKTDMMGLVELQRKYRDSKPLKGARITGSLHLTIETSVLVETLYELGAEIRWCSCNIYSTQDHAAAALVKKNIATVFAWKNETIEDYWVCLNDAMTWRNPNDKDKICGPNLIVDDGGDATLILHEGVKAEIEYEKYNKIPEYLETELDENGKQLSMDLKCMYKVLKMELLKNPFRWRGMLKDLYGVSEETTTGVLRLKIMESEGKLLLPAINVNDSVTKSKFDNTYGCRQSLLHGLFNGCIQMLAGKKIVVLGYGEVGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDVVSEADIFITATGNKDVITVEHMRKMKENAYIANIGHFDDEIDVYGLENYPGIKVIEVKQNVHKFTFPDTQKSVILLCKGRLVNLGCATGHPPLVMSMSFTNQVLAQMDLWKSRELVDRSKTRFFVKKLSKELDEYVARLHLDVLGIKLTKLTETQAKYINVSINGPYKSEDYRY 5tj9 A 2.60 BS02 NAD A 1 T212 T213 T214 N246 C250 G275 G277 E278 V279 T297 E298 I299 D300 C303 T331 G332 N333 I354 G355 H356 N403 H410 T211 T212 T213 N245 C249 G274 G276 E277 V278 T296 E297 I298 D299 C302 T330 G331 N332 I353 G354 H355 N402 H409 3.3.1.1 Q5CPH1 KMESRIKDISLAEFGLQDMEIAKTDMMGLVELQRKYRDSKPLKGARITGSLHLTIETSVLVETLYELGAEIRWCSCNIYSTQDHAAAALVKKNIATVFAWKNETIEDYWVCLNDAMTWRNPNDKDKICGPNLIVDDGGDATLILHEGVKAEIEYEKYNKIPEYLETELDENGKQLSMDLKCMYKVLKMELLKNPFRWRGMLKDLYGVSEETTTGVLRLKIMESEGKLLLPAINVNDSVTKSKFDNTYGCRQSLLHGLFNGCIQMLAGKKIVVLGYGEVGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDVVSEADIFITATGNKDVITVEHMRKMKENAYIANIGHFDDEIDVYGLENYPGIKVIEVKQNVHKFTFPDTQKSVILLCKGRLVNLGCATGHPPLVMSMSFTNQVLAQMDLWKSRELVDRSKTRFFVKKLSKELDEYVARLHLDVLGIKLTKLTETQAKYINVSINGPYKSEDYRY