2n4q B BS01 III A 1 L507 V508 H511 Q524 V527 I538 T542 F543 D544 F545 D546 L547 L9 V10 H13 Q26 V29 I40 T44 F45 D46 F47 D48 L49 P42568 MDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS 4xnh A 2.10 BS01 I6P A 1 K349 I422 R426 K429 H430 K457 K460 Y461 R464 K323 I396 R400 K403 H404 K431 K434 Y435 R438 P12945 QFLEALKLYEGKQYKKSLKLLDAILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPTQDPIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKNDDSVNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLASLKKEQIANDIKENQWLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLKKRKETEAKSVAAYPSDQDNDVFGEKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVLLHATRNDTPFDPILKKVVTKSLEKEYSENFPLNEISNNSFDWLNFYQEKFGKNDINGLLFLYRYRDDVPIGSSNLKEMIISSLSPLEPHSQNEILQYYL 4xnh B 2.10 BS01 III F 1 E26 Y28 Y32 T116 H153 Y180 Y181 Q182 E25 Y27 Y31 T92 H129 Y156 Y157 Q158 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDCEDRTIKLDPTYLAPGEKLVGYVLVKMNDDPNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRREKLEDDLESDLLE 4xnh B 2.10 BS02 I6P A 1 K80 Y85 K91 T123 Y124 K59 Y64 K70 T99 Y100 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDCEDRTIKLDPTYLAPGEKLVGYVLVKMNDDPNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRREKLEDDLESDLLE 4xnh B 2.10 BS03 CMC B 1 N23 L24 S117 L118 S119 V120 R125 R126 M127 G128 A130 E131 H153 V154 N158 R159 A160 A161 H163 L164 Y165 T168 R207 N22 L23 S93 L94 S95 V96 R101 R102 M103 G104 A106 E107 H129 V130 N134 R135 A136 A137 H139 L140 Y141 T144 R183 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDCEDRTIKLDPTYLAPGEKLVGYVLVKMNDDPNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRREKLEDDLESDLLE 4xnh C 2.10 BS01 ACO C 1 T26 V27 L30 Y31 E94 F95 L96 G97 V98 R103 H104 K105 S106 I107 G108 S109 V129 Y130 L131 T138 W141 T24 V25 L28 Y29 E77 F78 L79 G80 V81 R86 H87 K88 S89 I90 G91 S92 V112 Y113 L114 T121 W124 2.3.1.- Q08689 RDICTLDNVYANNLGMLTKLAHVTVPNLYQDAFFSALFAEKDVHFTQMAYYSEIPVGGLVAKLVPKNELSLKGIQIEFLGVLPNYRHKSIGSKLLKFAEDKCSECHQHNVFVYLPAVDDLTKQWFIAHGFEQVGETVNNFIKGVNGDEQDAILLKKHIS 4xpd A 2.81 BS01 G4P A 1 K349 Q353 R426 K429 K457 K460 Y461 K323 Q327 R400 K403 K431 K434 Y435 P12945 DQFLEALKLYEGKQYKKSLKLLDAILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKISPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPTQDPIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKNDDSVNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLASLKKQIANDIKENQWLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLKKRKETEAKSVAAYPSDQDNDVFGEKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVLLHATRNDTPFVVTKSLEKEYSENFPLNEFDWLNFYQEKFGKNDINGLLFLYRYRDDVPIGSSNLKEMIISSLSPLEPHSQNEILQYYL 4xpd B 2.81 BS01 III F 1 E26 Y28 Y32 T116 H153 Y180 Y181 Q182 E25 Y27 Y31 T83 H120 Y147 Y148 Q149 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDPTYLAPGEKLVGYVLVKMNDDQNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRRKLEDDLESDLLE 4xpd B 2.81 BS02 G4P A 1 P83 Y85 K91 P53 Y55 K61 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDPTYLAPGEKLVGYVLVKMNDDQNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRRKLEDDLESDLLE 4xpd B 2.81 BS03 CMC F 1 N23 L24 S117 L118 S119 V120 R125 R126 M127 G128 I129 A130 E131 L152 H153 V154 N158 A160 A161 H163 L164 Y165 T168 N22 L23 S84 L85 S86 V87 R92 R93 M94 G95 I96 A97 E98 L119 H120 V121 N125 A127 A128 H130 L131 Y132 T135 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDPTYLAPGEKLVGYVLVKMNDDQNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRRKLEDDLESDLLE 4xpd C 2.81 BS01 ACO C 1 V27 L30 Y31 I93 E94 L96 R103 H104 K105 S106 G108 S109 V129 Y130 L131 W141 H145 V25 L28 Y29 I72 E73 L75 R82 H83 K84 S85 G87 S88 V108 Y109 L110 W120 H124 2.3.1.- Q08689 RDICTLDNVYANNLGMLTKLAHVTVPNLYQDAFFSALFAEDVHFTQMAYYSEIPVGGLVAKLVPLSLKGIQIEFLGVLPNYRHKSIGSKLLKFAEDKCSECHQHNVFVYLPAVDDLTKQWFIAHGFEQVGETVNNFIKGVNGDEQDAILLKKHIS 4ymp A 3.15 BS01 HEM A 1 K19 S26 Y27 Y31 F55 F56 M103 I105 Y112 K114 F116 I118 K10 S17 Y18 Y22 F46 F47 M87 I89 Y96 K98 F100 I102 VFDAVIKAYKDNSDEESYATVYIKDPKLTIENGKRIITATLKDSDFFDYLKVEFHDVKVLSEDKRKHGTKVIQFEVGELGKRYNMQMHILIPTLGYDKEFKIQFEVNMRTFV 4ymp C 3.15 BS01 HEM C 1 K19 S26 Y27 Y31 I105 Y112 K114 F116 I118 K8 S15 Y16 Y20 I80 Y87 K89 F91 I93 DAVIKAYKDNSDEESYATVYIKDPKLTIRIITATLKDSDFFDYLKVFHDVKVLSEDKRKHGTKVIQFEVLGKRYNMQMHILIPTLGYDKEFKIQFEVNMRTFV 4ysf A 1.94 BS01 FE2 A 1 H86 H88 H140 H83 H85 H137 1.13.11.20 P21816 TELLKPRTLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLNLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTP 4z0x A 2.00 BS01 III C 1 G28 D29 K30 Y31 D50 W90 S93 G27 D28 K29 Y30 D49 W89 S92 YVLTQPPSVSVAPGQTASITCSGDKLGDKYVSWYQQRPGQSPVLVLYQDSKRPSGIPERFSGSNSGNTATLTISGTQAMDEADYYCQAWDSSALVFGGGTKLTVL 4z0x B 2.00 BS01 III C 1 I77 F80 T82 M84 L126 S127 R128 G129 I51 F54 T56 M58 L100 S101 R102 G103 VQPVQSGAEVKKPGSSVKVSCEASGGTHSNYVITWVRQAPGQGLEWMGGFIPDFRTAMYAQGFQGRVTITADESTSLAYMELTNLRSEDTAVYYCARGPLSRGYYDYWGPGTLVTVSSGST 4z9h A 1.45 BS01 ASP B 1 R69 R73 R43 R47 P07017 27292793 SLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNAMGEAFAQYALSSEKLYRDIVTDNADDYRFAQ 4z9h B 1.45 BS01 ASP B 1 R64 Y149 F150 Q152 T154 R32 Y117 F118 Q120 T122 P07017 27292793 LHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNAMGEAFAQYALSSEKLYRDIVTDNADDYRFA 4z9i A 1.57 BS01 ASP B 1 R69 R73 R42 R46 P07017 27292793 LFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNAMGEAFAQYALSSEKLYRDIVTDNADDYRFAQ 4z9i B 1.57 BS01 ASP B 1 R64 Y149 F150 Q152 T154 R33 Y118 F119 Q121 T123 P07017 27292793 SLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNAMGEAFAQYALSSEKLYRDIVTDNADDYRFAQ 4z9k A 1.50 BS01 ZN A 1 E103 H107 E99 H103 3.2.2.22 P02879 KQYPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAITHLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYSTGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALMVYRCAP 4zcw A 1.99 BS01 4NG A 1 G38 A39 S40 Q166 E167 E210 D245 E293 D318 L341 K343 H371 R372 S373 K394 G37 A38 S39 Q165 E166 E209 D244 E292 D317 L340 K342 H370 R371 S372 K393 4.2.1.11 P09104 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 4zcw A 1.99 BS02 MG A 1 D245 E293 D318 K394 D244 E292 D317 K393 4.2.1.11 P09104 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 4zcw B 1.99 BS01 4NG B 1 G38 A39 S40 Q166 E167 E210 D245 E293 D318 L341 K343 H371 R372 S373 K394 G37 A38 S39 Q165 E166 E209 D244 E292 D317 L340 K342 H370 R371 S372 K393 4.2.1.11 P09104 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 4zcw B 1.99 BS02 MG B 1 D245 E293 D318 K343 K394 D244 E292 D317 K342 K393 4.2.1.11 P09104 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 4zrp A 2.10 BS01 CNC A 1 G85 Q86 Y137 Q138 D176 N224 Y226 S227 M270 Q273 S357 L358 S359 G360 P361 Y362 L363 F376 W377 Q378 L379 L387 L388 G390 W409 G76 Q77 Y128 Q129 D167 N215 Y217 S218 M261 Q264 S348 L349 S350 G351 P352 Y353 L354 F367 W368 Q369 L370 L378 L379 G381 W400 P20062 EMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVQEEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW 4zrp A 2.10 BS02 CA A 1 Y226 A264 Q266 N267 Q389 Y217 A255 Q257 N258 Q380 P20062 EMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVQEEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW 4zrp B 2.10 BS01 CNC B 1 G85 Q86 Y137 Q138 D176 N224 Y226 S227 M270 Q273 S357 L358 S359 G360 P361 Y362 L363 F376 W377 Q378 L379 L387 L388 G390 W409 G75 Q76 Y127 Q128 D166 N214 Y216 S217 M260 Q263 S347 L348 S349 G350 P351 Y352 L353 F366 W367 Q368 L369 L377 L378 G380 W399 P20062 EMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVQEEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW 4zrp C 2.10 BS01 CA C 1 W150 D153 H155 D157 D163 E164 W58 D61 H63 D65 D71 E72 Q9NPF0 SCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCGTN 4zrp C 2.10 BS02 CA C 2 W72 D75 D77 D79 D85 E86 W20 D23 D25 D27 D33 E34 Q9NPF0 SCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCGTN 4zrp D 2.10 BS01 CA D 1 W150 D153 H155 D157 D163 E164 W58 D61 H63 D65 D71 E72 Q9NPF0 SCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCGTNE 4zrp D 2.10 BS02 CA D 2 W72 D75 D77 D79 D85 E86 W20 D23 D25 D27 D33 E34 Q9NPF0 SCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCGTNE 4zrq A 2.60 BS01 CNC A 1 G85 Q86 T134 Y137 Q138 D176 N224 Y226 S227 M270 S357 L358 S359 G360 P361 Y362 L363 F376 W377 Q378 L379 L387 L388 G390 W409 G76 Q77 T125 Y128 Q129 D167 N215 Y217 S218 M261 S348 L349 S350 G351 P352 Y353 L354 F367 W368 Q369 L370 L378 L379 G381 W400 P20062 EMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVQEEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW 4zrq B 2.60 BS01 CNC B 1 G85 Q86 T134 Y137 Q138 D176 N224 Y226 S227 M270 Q273 S357 L358 S359 G360 P361 Y362 L363 F376 W377 Q378 L379 L387 L388 G390 W409 G75 Q76 T124 Y127 Q128 D166 N214 Y216 S217 M260 Q263 S347 L348 S349 G350 P351 Y352 L353 F366 W367 Q368 L369 L377 L378 G380 W399 P20062 EMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVQEEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW 4zrq C 2.60 BS01 CA C 1 W150 D153 H155 D157 D163 E164 W55 D58 H60 D62 D68 E69 Q9NPF0 SCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCGTNE 4zrq C 2.60 BS02 CA C 2 W72 C74 D75 D77 D79 D85 W20 C22 D23 D25 D27 D33 Q9NPF0 SCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCGTNE 4zrq D 2.60 BS01 CA D 1 W150 D153 H155 D157 D163 E164 W55 D58 H60 D62 D68 E69 Q9NPF0 SCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCGTN 4zrq D 2.60 BS02 CA D 2 W72 C74 D75 D77 D79 D85 W20 C22 D23 D25 D27 D33 Q9NPF0 SCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGCGTN 4zs0 A 3.00 BS01 4QV A 1 L139 V147 A160 L194 E211 Y212 A213 G216 L263 D274 L13 V21 A34 L68 E85 Y86 A87 G90 L137 D148 2.7.11.1 O14965 27391133 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 4ztq A 2.80 BS01 4RM A 1 L139 G140 G142 V147 A160 K162 Q185 L196 L210 E211 Y212 A213 L263 A273 D274 L13 G14 G16 V21 A34 K36 Q59 L70 L84 E85 Y86 A87 L137 A147 D148 2.7.11.1 O14965 27391133 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVGTLDYLPPEMIEGEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 4ztr A 2.85 BS01 4RJ A 1 R137 L139 G140 G142 V147 A160 K162 L194 R195 L196 L210 E211 Y212 A213 G216 R220 L263 A273 D274 F275 R11 L13 G14 G16 V21 A34 K36 L68 R69 L70 L84 E85 Y86 A87 G90 R94 L137 A147 D148 F149 2.7.11.1 O14965 27391133 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 4zts A 2.90 BS01 4RK A 1 R137 L139 G140 G142 V147 A160 K162 Q185 L196 L210 E211 A213 P214 G216 L263 A273 D274 F275 R11 L13 G14 G16 V21 A34 K36 Q59 L70 L84 E85 A87 P88 G90 L137 A147 D148 F149 2.7.11.1 O14965 27391133 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 5anz A 1.61 BS01 CA A 1 D219 D221 D223 K225 D234 D174 D176 D178 K180 D189 Q9HX28 27035839 GQSFEQWRDAFRQQALAGGIDAQTFDRAFAGVQPDPAVVEADRSQPEFTRPVWKYLEGALDPLRVRQGQARLAQHARILGEVDARYAVDADAVVAIWGMESNYGSHMGNKNVIRSLATLAYEGRRPEFAHAQLLAALKILQHGDVPASFMIGSWAGAMGQTQFIPTTHNQYAVDFDGDGKRDIWGSPGDALASTANYLKASGWIAGQPWGFEVRLPAGFDYSLAELTIRKPLGEWQGMGVQGVNGGPLPSGLSGEQASLLLPAGHRGPAFLVLHNFRAILKYNNSSAYALAVGLLADSFKGGGRIVGAWPLEDVPLSRSQRIELQRQLAARGHDPGAVDGIIGANTRKAIRACQQEFGWPADGYPTPALLDRLRT 5ao7 A 2.09 BS01 CA A 1 D219 D221 D223 K225 D234 D174 D176 D178 K180 D189 Q9HX28 27035839 GQSFEQWRDAFRQQALAGGIDAQTFDRAFAGVQPDPAVVEADRSQPEFTRPVWKYLEGALDPLRVRQGQARLAQHARILGEVDARYAVDADAVVAIWGMESNYGSHMGNKNVIRSLATLAYEGRRPEFAHAQLLAALKILQHGDVPASFMIGSWAGAMGQTQFIPTTHNQYAVDFDGDGKRDIWGSPGDALASTANYLKASGWIAGQPWGFEVRLPAGFDYSLAELTIRKPLGEWQGMGVQGVNGGPLPSGLSGEQASLLLPAGHRGPAFLVLHNFRAILKYNNSSAYALAVGLLADSFKGGGRIVGAWPLEDVPLSRSQRIELQRQLAARGHDPGAVDGIIGANTRKAIRACQQEFGWPADGYPTPALLDRLRT 5ao7 A 2.09 BS02 AH0 A 1 M144 E145 N147 M99 E100 N102 Q9HX28 27035839 GQSFEQWRDAFRQQALAGGIDAQTFDRAFAGVQPDPAVVEADRSQPEFTRPVWKYLEGALDPLRVRQGQARLAQHARILGEVDARYAVDADAVVAIWGMESNYGSHMGNKNVIRSLATLAYEGRRPEFAHAQLLAALKILQHGDVPASFMIGSWAGAMGQTQFIPTTHNQYAVDFDGDGKRDIWGSPGDALASTANYLKASGWIAGQPWGFEVRLPAGFDYSLAELTIRKPLGEWQGMGVQGVNGGPLPSGLSGEQASLLLPAGHRGPAFLVLHNFRAILKYNNSSAYALAVGLLADSFKGGGRIVGAWPLEDVPLSRSQRIELQRQLAARGHDPGAVDGIIGANTRKAIRACQQEFGWPADGYPTPALLDRLRT 5ao7 A 2.09 BS03 NAG A 1 M144 E145 H151 M152 G153 Q207 N328 Y333 M99 E100 H106 M107 G108 Q162 N283 Y288 Q9HX28 27035839 GQSFEQWRDAFRQQALAGGIDAQTFDRAFAGVQPDPAVVEADRSQPEFTRPVWKYLEGALDPLRVRQGQARLAQHARILGEVDARYAVDADAVVAIWGMESNYGSHMGNKNVIRSLATLAYEGRRPEFAHAQLLAALKILQHGDVPASFMIGSWAGAMGQTQFIPTTHNQYAVDFDGDGKRDIWGSPGDALASTANYLKASGWIAGQPWGFEVRLPAGFDYSLAELTIRKPLGEWQGMGVQGVNGGPLPSGLSGEQASLLLPAGHRGPAFLVLHNFRAILKYNNSSAYALAVGLLADSFKGGGRIVGAWPLEDVPLSRSQRIELQRQLAARGHDPGAVDGIIGANTRKAIRACQQEFGWPADGYPTPALLDRLRT 5ao7 A 2.09 BS04 NAG A 2 Q207 F208 I209 T212 Y242 K326 Y327 Q162 F163 I164 T167 Y197 K281 Y282 Q9HX28 27035839 GQSFEQWRDAFRQQALAGGIDAQTFDRAFAGVQPDPAVVEADRSQPEFTRPVWKYLEGALDPLRVRQGQARLAQHARILGEVDARYAVDADAVVAIWGMESNYGSHMGNKNVIRSLATLAYEGRRPEFAHAQLLAALKILQHGDVPASFMIGSWAGAMGQTQFIPTTHNQYAVDFDGDGKRDIWGSPGDALASTANYLKASGWIAGQPWGFEVRLPAGFDYSLAELTIRKPLGEWQGMGVQGVNGGPLPSGLSGEQASLLLPAGHRGPAFLVLHNFRAILKYNNSSAYALAVGLLADSFKGGGRIVGAWPLEDVPLSRSQRIELQRQLAARGHDPGAVDGIIGANTRKAIRACQQEFGWPADGYPTPALLDRLRT 5ao8 A 2.09 BS01 CA A 1 D219 D221 D223 K225 D234 D174 D176 D178 K180 D189 Q9HX28 27035839 GQSFEQWRDAFRQQALAGGIDAQTFDRAFAGVQPDPAVVEADRSQPEFTRPVWKYLEGALDPLRVRQGQARLAQHARILGEVDARYAVDADAVVAIWGMESNYGSHMGNKNVIRSLATLAYEGRRPEFAHAQLLAALKILQHGDVPASFMIGSWAGAMGQTQFIPTTHNQYAVDFDGDGKRDIWGSPGDALASTANYLKASGWIAGQPWGFEVRLPAGFDYSLAELTIRKPLGEWQGMGVQGVNGGPLPSGLSGEQASLLLPAGHRGPAFLVLHNFRAILKYNNSSAYALAVGLLADSFKGGGRIVGAWPLDDVPLSRSQRIELQRQLAARGHDPGAVDGIIGANTRKAIRACQQEFGWPADGYPTPALLDRLR 5ao8 A 2.09 BS02 NAG A 1 Q207 F208 I209 T212 Y242 K326 Y327 Q162 F163 I164 T167 Y197 K281 Y282 Q9HX28 27035839 GQSFEQWRDAFRQQALAGGIDAQTFDRAFAGVQPDPAVVEADRSQPEFTRPVWKYLEGALDPLRVRQGQARLAQHARILGEVDARYAVDADAVVAIWGMESNYGSHMGNKNVIRSLATLAYEGRRPEFAHAQLLAALKILQHGDVPASFMIGSWAGAMGQTQFIPTTHNQYAVDFDGDGKRDIWGSPGDALASTANYLKASGWIAGQPWGFEVRLPAGFDYSLAELTIRKPLGEWQGMGVQGVNGGPLPSGLSGEQASLLLPAGHRGPAFLVLHNFRAILKYNNSSAYALAVGLLADSFKGGGRIVGAWPLDDVPLSRSQRIELQRQLAARGHDPGAVDGIIGANTRKAIRACQQEFGWPADGYPTPALLDRLR 5ao8 A 2.09 BS03 NAG A 2 Y100 M144 E145 H151 M152 G153 Q207 N328 Y333 Y55 M99 E100 H106 M107 G108 Q162 N283 Y288 Q9HX28 27035839 GQSFEQWRDAFRQQALAGGIDAQTFDRAFAGVQPDPAVVEADRSQPEFTRPVWKYLEGALDPLRVRQGQARLAQHARILGEVDARYAVDADAVVAIWGMESNYGSHMGNKNVIRSLATLAYEGRRPEFAHAQLLAALKILQHGDVPASFMIGSWAGAMGQTQFIPTTHNQYAVDFDGDGKRDIWGSPGDALASTANYLKASGWIAGQPWGFEVRLPAGFDYSLAELTIRKPLGEWQGMGVQGVNGGPLPSGLSGEQASLLLPAGHRGPAFLVLHNFRAILKYNNSSAYALAVGLLADSFKGGGRIVGAWPLDDVPLSRSQRIELQRQLAARGHDPGAVDGIIGANTRKAIRACQQEFGWPADGYPTPALLDRLR 5ao8 A 2.09 BS04 NM9 A 1 R109 G143 M144 E145 S146 N147 H151 R64 G98 M99 E100 S101 N102 H106 Q9HX28 27035839 GQSFEQWRDAFRQQALAGGIDAQTFDRAFAGVQPDPAVVEADRSQPEFTRPVWKYLEGALDPLRVRQGQARLAQHARILGEVDARYAVDADAVVAIWGMESNYGSHMGNKNVIRSLATLAYEGRRPEFAHAQLLAALKILQHGDVPASFMIGSWAGAMGQTQFIPTTHNQYAVDFDGDGKRDIWGSPGDALASTANYLKASGWIAGQPWGFEVRLPAGFDYSLAELTIRKPLGEWQGMGVQGVNGGPLPSGLSGEQASLLLPAGHRGPAFLVLHNFRAILKYNNSSAYALAVGLLADSFKGGGRIVGAWPLDDVPLSRSQRIELQRQLAARGHDPGAVDGIIGANTRKAIRACQQEFGWPADGYPTPALLDRLR 5aq1 A 2.65 BS01 BG6 A 1 K217 H247 Y248 K251 E285 D304 H309 K403 R408 Q437 K156 H186 Y187 K190 E224 D243 H248 K342 R347 Q376 1.1.1.49 Q4E0B2 27391210 PELRSRALTIVVLGASGDLAKKKTFPALFQLYCNGMLPRDVNILGYARSTMEDVEKWKKDTLAGFFTRLDERGCHVGNFLRRISYMTGSYDRDEDFARLNERILRMEEAFQGPEKGGNRLFYLALPPSVFVGVCRGLSKGAMQKPELGWVRLIVEKPFGRDTETSEQLSNQLKPLFNERQVFRIDHYLGKEMVQNIIVTRFANRVFSALWNSNSIACVQITFKEKIGTAGRGGYFDSIGIIRDVIQNHLTQILSLLTMEKPRSLSAEDIRDEKVQVLRQVVPANPAECVLGQYTASADGSTPGYLDDPSVPKGSHCPTFAVLRLHVNNDRWHGVPFIIRAGKALEERLLDIRIQFKDEIRPFGESTQRNELVIRAQPSEAMYLKLTAKTPGLLNDTHQTELDLTYERRYDVTLPDAYESLIHEALLGNSTNFVRVDELDAAWRIYTPLLHAIDRGEVKVLPYAAGSCGPEEAQEFIRISGYKTT 5aq1 A 2.65 BS02 NDP A 1 S77 G78 D79 L80 A108 R109 S110 Y151 A185 L186 P187 V190 E216 K217 P218 S16 G17 D18 L19 A47 R48 S49 Y90 A124 L125 P126 V129 E155 K156 P157 1.1.1.49 Q4E0B2 27391210 PELRSRALTIVVLGASGDLAKKKTFPALFQLYCNGMLPRDVNILGYARSTMEDVEKWKKDTLAGFFTRLDERGCHVGNFLRRISYMTGSYDRDEDFARLNERILRMEEAFQGPEKGGNRLFYLALPPSVFVGVCRGLSKGAMQKPELGWVRLIVEKPFGRDTETSEQLSNQLKPLFNERQVFRIDHYLGKEMVQNIIVTRFANRVFSALWNSNSIACVQITFKEKIGTAGRGGYFDSIGIIRDVIQNHLTQILSLLTMEKPRSLSAEDIRDEKVQVLRQVVPANPAECVLGQYTASADGSTPGYLDDPSVPKGSHCPTFAVLRLHVNNDRWHGVPFIIRAGKALEERLLDIRIQFKDEIRPFGESTQRNELVIRAQPSEAMYLKLTAKTPGLLNDTHQTELDLTYERRYDVTLPDAYESLIHEALLGNSTNFVRVDELDAAWRIYTPLLHAIDRGEVKVLPYAAGSCGPEEAQEFIRISGYKTT 5aq1 B 2.65 BS01 BG6 B 1 K217 H247 Y248 K251 E285 D304 H309 K403 R408 Q437 K156 H186 Y187 K190 E224 D243 H248 K342 R347 Q376 1.1.1.49 Q4E0B2 27391210 PELRSRALTIVVLGASGDLAKKKTFPALFQLYCNGMLPRDVNILGYARSTMEDVEKWKKDTLAGFFTRLDERGCHVGNFLRRISYMTGSYDRDEDFARLNERILRMEEAFQGPEKGGNRLFYLALPPSVFVGVCRGLSKGAMQKPELGWVRLIVEKPFGRDTETSEQLSNQLKPLFNERQVFRIDHYLGKEMVQNIIVTRFANRVFSALWNSNSIACVQITFKEKIGTAGRGGYFDSIGIIRDVIQNHLTQILSLLTMEKPRSLSAEDIRDEKVQVLRQVVPANPAECVLGQYTASADGSTPGYLDDPSVPKGSHCPTFAVLRLHVNNDRWHGVPFIIRAGKALEERLLDIRIQFKDEIRPFGESTQRNELVIRAQPSEAMYLKLTAKTPGLLNDTHQTELDLTYERRYDVTLPDAYESLIHEALLGNSTNFVRVDELDAAWRIYTPLLHAIDRGEVKVLPYAAGSCGPEEAQEFIRISGYKTT 5aq1 B 2.65 BS02 NDP B 1 S77 G78 D79 L80 A108 R109 S110 Y151 A185 L186 P187 V190 E216 K217 P218 S16 G17 D18 L19 A47 R48 S49 Y90 A124 L125 P126 V129 E155 K156 P157 1.1.1.49 Q4E0B2 27391210 PELRSRALTIVVLGASGDLAKKKTFPALFQLYCNGMLPRDVNILGYARSTMEDVEKWKKDTLAGFFTRLDERGCHVGNFLRRISYMTGSYDRDEDFARLNERILRMEEAFQGPEKGGNRLFYLALPPSVFVGVCRGLSKGAMQKPELGWVRLIVEKPFGRDTETSEQLSNQLKPLFNERQVFRIDHYLGKEMVQNIIVTRFANRVFSALWNSNSIACVQITFKEKIGTAGRGGYFDSIGIIRDVIQNHLTQILSLLTMEKPRSLSAEDIRDEKVQVLRQVVPANPAECVLGQYTASADGSTPGYLDDPSVPKGSHCPTFAVLRLHVNNDRWHGVPFIIRAGKALEERLLDIRIQFKDEIRPFGESTQRNELVIRAQPSEAMYLKLTAKTPGLLNDTHQTELDLTYERRYDVTLPDAYESLIHEALLGNSTNFVRVDELDAAWRIYTPLLHAIDRGEVKVLPYAAGSCGPEEAQEFIRISGYKTT 5aq1 C 2.65 BS01 BG6 C 1 K217 H247 Y248 K251 E285 D304 H309 K403 Q437 K156 H186 Y187 K190 E224 D243 H248 K342 Q376 1.1.1.49 Q4E0B2 27391210 PELRSRALTIVVLGASGDLAKKKTFPALFQLYCNGMLPRDVNILGYARSTMEDVEKWKKDTLAGFFTRLDERGCHVGNFLRRISYMTGSYDRDEDFARLNERILRMEEAFQGPEKGGNRLFYLALPPSVFVGVCRGLSKGAMQKPELGWVRLIVEKPFGRDTETSEQLSNQLKPLFNERQVFRIDHYLGKEMVQNIIVTRFANRVFSALWNSNSIACVQITFKEKIGTAGRGGYFDSIGIIRDVIQNHLTQILSLLTMEKPRSLSAEDIRDEKVQVLRQVVPANPAECVLGQYTASADGSTPGYLDDPSVPKGSHCPTFAVLRLHVNNDRWHGVPFIIRAGKALEERLLDIRIQFKDEIRPFGESTQRNELVIRAQPSEAMYLKLTAKTPGLLNDTHQTELDLTYERRYDVTLPDAYESLIHEALLGNSTNFVRVDELDAAWRIYTPLLHAIDRGEVKVLPYAAGSCGPEEAQEFIRISGYKTT 5aq1 C 2.65 BS02 NDP C 1 S77 G78 D79 L80 A108 R109 S110 Y151 A185 L186 P187 V190 E216 K217 P218 S16 G17 D18 L19 A47 R48 S49 Y90 A124 L125 P126 V129 E155 K156 P157 1.1.1.49 Q4E0B2 27391210 PELRSRALTIVVLGASGDLAKKKTFPALFQLYCNGMLPRDVNILGYARSTMEDVEKWKKDTLAGFFTRLDERGCHVGNFLRRISYMTGSYDRDEDFARLNERILRMEEAFQGPEKGGNRLFYLALPPSVFVGVCRGLSKGAMQKPELGWVRLIVEKPFGRDTETSEQLSNQLKPLFNERQVFRIDHYLGKEMVQNIIVTRFANRVFSALWNSNSIACVQITFKEKIGTAGRGGYFDSIGIIRDVIQNHLTQILSLLTMEKPRSLSAEDIRDEKVQVLRQVVPANPAECVLGQYTASADGSTPGYLDDPSVPKGSHCPTFAVLRLHVNNDRWHGVPFIIRAGKALEERLLDIRIQFKDEIRPFGESTQRNELVIRAQPSEAMYLKLTAKTPGLLNDTHQTELDLTYERRYDVTLPDAYESLIHEALLGNSTNFVRVDELDAAWRIYTPLLHAIDRGEVKVLPYAAGSCGPEEAQEFIRISGYKTT 5awa A 2.20 BS01 M8D A 1 G351 S352 Y353 V378 I403 F405 G305 S306 Y307 V332 I357 F359 Q9NR97 RSYPCDEKKQSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICARGKSIVS 5awc A 2.50 BS01 M4D A 1 V520 D543 D545 G572 T574 V451 D474 D476 G503 T505 Q9NR97 SRSYPCDEKKQVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE 5awc A 2.50 BS02 M4D B 1 F346 Y348 S352 Y353 G376 V378 I403 F405 F301 Y303 S307 Y308 G331 V333 I358 F360 Q9NR97 SRSYPCDEKKQVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE 5awc B 2.50 BS01 M4D A 1 Y348 S352 Y353 G376 V378 I403 F405 Y303 S307 Y308 G331 V333 I358 F360 Q9NR97 SRSYPCDEKKQVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSL 5awc B 2.50 BS02 M4D B 1 V520 D543 D545 G572 T574 V450 D473 D475 G502 T504 Q9NR97 SRSYPCDEKKQVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSL 5awc C 2.50 BS01 M4D C 1 V520 D543 D545 G572 T574 V447 D470 D472 G499 T501 Q9NR97 SRSYPCDEKVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPLKHLDLSSNLLKTINKSKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSL 5awc C 2.50 BS02 M4D D 1 F346 S352 Y353 V378 F405 F298 S304 Y305 V330 F357 Q9NR97 SRSYPCDEKVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPLKHLDLSSNLLKTINKSKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSL 5awc D 2.50 BS01 M4D C 1 Y348 G351 S352 Y353 G376 V378 I403 F405 Y291 G294 S295 Y296 G319 V321 I346 F348 Q9NR97 SYPCDEAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNEQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIV 5awc D 2.50 BS02 M4D D 1 D543 D545 G572 T574 D459 D461 G488 T490 Q9NR97 SYPCDEAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNEQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIV 5btv A 1.70 BS01 III P 1 K49 R56 R129 Y130 L174 N175 V178 N226 K53 R60 R126 Y127 L171 N172 V175 N223 P31947 26103986 AMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQCSNGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 5byt A 2.00 BS01 MG A 1 S119 E252 S96 E229 2.4.2.18 P9WFX5 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 5byt A 2.00 BS02 PRP A 1 V106 G107 G109 G110 N117 S119 T120 K135 N138 A140 A141 S142 S143 G146 G147 E252 V83 G84 G86 G87 N94 S96 T97 K112 N115 A117 A118 S119 S120 G123 G124 E229 2.4.2.18 P9WFX5 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 5byt B 2.00 BS01 MG B 1 S119 E252 S96 E229 2.4.2.18 P9WFX5 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 5byt B 2.00 BS02 PRP B 1 V106 G107 G109 G110 N117 L118 S119 T120 K135 N138 R139 A140 A141 S142 S143 G146 G147 E252 V83 G84 G86 G87 N94 L95 S96 T97 K112 N115 R116 A117 A118 S119 S120 G123 G124 E229 2.4.2.18 P9WFX5 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 5c1r A 1.80 BS01 MG A 1 S119 E252 S95 E228 2.4.2.18 P9WFX5 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 5c1r A 1.80 BS02 MG A 2 D111 V113 D87 V89 2.4.2.18 P9WFX5 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 5c1r A 1.80 BS03 51N A 1 V106 G107 G109 G110 N117 S119 T120 K135 N138 R139 A140 A141 S142 S143 E252 V82 G83 G85 G86 N93 S95 T96 K111 N114 R115 A116 A117 S118 S119 E228 2.4.2.18 P9WFX5 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 5c1r B 1.80 BS01 MG B 1 S119 E252 S96 E229 2.4.2.18 P9WFX5 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 5c1r B 1.80 BS02 MG B 2 D111 V113 D88 V90 2.4.2.18 P9WFX5 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 5c1r B 1.80 BS03 51N B 1 V106 G107 G109 G110 N117 L118 S119 T120 K135 N138 R139 A140 A141 S142 S143 E252 V83 G84 G86 G87 N94 L95 S96 T97 K112 N115 R116 A117 A118 S119 S120 E229 2.4.2.18 P9WFX5 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 5c80 A 2.24 BS01 URI A 1 I68 T93 T94 G95 Q165 R167 E195 M196 E197 I220 I66 T91 T92 G93 Q163 R165 E193 M194 E195 I218 2.4.2.3 Q9K4U1 KTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5c80 B 2.24 BS01 URI B 1 I68 R90 T93 T94 G95 F161 Q165 R167 E195 M196 E197 I220 I67 R89 T92 T93 G94 F160 Q164 R166 E194 M195 E196 I219 2.4.2.3 Q9K4U1 TKTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5c80 C 2.24 BS01 URI C 1 T93 T94 G95 F161 Q165 M196 E197 T91 T92 G93 F159 Q163 M194 E195 2.4.2.3 Q9K4U1 KTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5c80 D 2.24 BS01 URI D 1 I68 T93 T94 G95 F161 Q165 R167 E195 M196 E197 I220 I66 T91 T92 G93 F159 Q163 R165 E193 M194 E195 I218 2.4.2.3 Q9K4U1 KTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPATLKETEARSIKVVVEAARKMLK 5c80 E 2.24 BS01 URI E 1 I68 T93 T94 G95 F161 Q165 R167 F194 E195 M196 E197 I219 I220 I66 T91 T92 G93 F159 Q163 R165 F192 E193 M194 E195 I217 I218 2.4.2.3 Q9K4U1 KTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5c80 F 2.24 BS01 URI F 1 I68 T93 T94 G95 F161 Q165 R167 E195 M196 E197 I66 T91 T92 G93 F159 Q163 R165 E193 M194 E195 2.4.2.3 Q9K4U1 KTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5cbf A 3.61 BS01 CA A 1 S59 L62 P63 M64 G65 S55 L58 P59 M60 G61 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbf B 3.61 BS01 CA B 1 P63 M64 P59 M60 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbf D 3.61 BS01 CA B 1 S59 L62 P63 M64 G65 S55 L58 P59 M60 G61 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbf E 3.61 BS01 CA A 1 P63 M64 P59 M60 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbg A 3.14 BS01 CA A 1 S59 L62 P63 M64 G65 S55 L58 P59 M60 G61 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbg D 3.14 BS01 CA B 1 S59 L62 P63 M64 G65 S55 L58 P59 M60 G61 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbg E 3.14 BS01 CA E 1 G65 N66 G61 N62 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbg F 3.14 BS01 CA F 1 S59 L62 P63 M64 G65 S55 L58 P59 M60 G61 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbg F 3.14 BS02 CA F 2 P71 K77 P67 K73 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbh A 3.37 BS01 CA A 1 S59 L62 P63 M64 G65 N66 S55 L58 P59 M60 G61 N62 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbh B 3.37 BS01 CA A 2 S59 L62 P63 G65 S55 L58 P59 G61 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbh B 3.37 BS02 CA D 1 P63 M64 P59 M60 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbh D 3.37 BS01 CA D 1 S59 L62 P63 M64 G65 S55 L58 P59 M60 G61 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbh D 3.37 BS02 CA E 1 P63 M64 P59 M60 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbh E 3.37 BS01 CA E 1 S59 L62 P63 M64 G65 S55 L58 P59 M60 G61 D5UM26 TLMFKRFFGAVRTSWRDPSTRGAVLSLAIIVTAATIFYTLAEKWSVIDSLFYAVSVGLPMGNGPLSPTLTLSKIFTLVYAILVVGLFVTVGGSLASAIVQNN 5cbt A 1.45 BS01 4ZL A 1 R55 F60 M61 Q63 G72 A101 N102 T107 Q111 F113 H126 R54 F59 M60 Q62 G71 A100 N101 T106 Q110 F112 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5cbu A 1.40 BS01 4ZM A 1 R55 F60 M61 Q63 G72 R82 A101 N102 A103 T107 Q111 F113 H126 R54 F59 M60 Q62 G71 R81 A100 N101 A102 T106 Q110 F112 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5cbu A 1.40 BS02 4ZM A 2 T52 H54 H70 N71 G150 S153 K154 K155 T51 H53 H69 N70 G149 S152 K153 K154 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5cbv A 1.80 BS01 4ZP A 1 R55 F60 M61 Q63 G72 T73 R82 A101 N102 Q111 F113 H126 R54 F59 M60 Q62 G71 T72 R81 A100 N101 Q110 F112 H125 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5cbw A 1.80 BS01 4ZO A 1 R55 F60 M61 Q63 G72 R82 A101 N102 A103 T107 Q111 F113 H126 R54 F59 M60 Q62 G71 R81 A100 N101 A102 T106 Q110 F112 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5ccn A 1.80 BS01 4ZZ A 1 R55 F60 M61 Q63 G72 T73 A101 N102 T107 Q111 F113 H126 R54 F59 M60 Q62 G71 T72 A100 N101 T106 Q110 F112 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5ccq A 1.80 BS01 502 A 1 R55 F60 M61 Q63 G72 T73 G74 A101 N102 Q111 F113 H126 R54 F59 M60 Q62 G71 T72 G73 A100 N101 Q110 F112 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5ccr A 1.90 BS01 4ZT A 1 R55 F60 M61 Q63 G72 R82 A101 N102 A103 G104 T107 G109 Q111 F113 H126 R54 F59 M60 Q62 G71 R81 A100 N101 A102 G103 T106 G108 Q110 F112 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5ccs X 2.10 BS01 C4Y X 1 R55 M61 Q63 G72 A101 N102 T107 G109 Q111 F113 H126 R54 M60 Q62 G71 A100 N101 T106 G108 Q110 F112 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGQHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5cfu A 1.82 BS01 MN A 1 D44 D46 D42 D44 Q6X3H6 TTQVTLIHKILAAADERNLPLWIGGGWAIDARLGRVTRKHDDIDLTFPGERRGELEAIVEMLGGRVMEELDYGFLAEIGDELLDCEPAWWADEAYEIAEAPQGSCPEAAEGVIAGRPVRCNSWEAIIWDYFYYADEVPPVDWPTKHIESYRLACTSLGAEKVEVLRAAFRSRYA 5cfu A 1.82 BS02 MN A 2 K147 H148 K145 H146 Q6X3H6 TTQVTLIHKILAAADERNLPLWIGGGWAIDARLGRVTRKHDDIDLTFPGERRGELEAIVEMLGGRVMEELDYGFLAEIGDELLDCEPAWWADEAYEIAEAPQGSCPEAAEGVIAGRPVRCNSWEAIIWDYFYYADEVPPVDWPTKHIESYRLACTSLGAEKVEVLRAAFRSRYA 5cfu A 1.82 BS03 51H A 1 D44 D46 Y74 D86 E88 I99 A100 D131 Y132 Y134 Y135 E138 H148 D42 D44 Y72 D84 E86 I97 A98 D129 Y130 Y132 Y133 E136 H146 Q6X3H6 TTQVTLIHKILAAADERNLPLWIGGGWAIDARLGRVTRKHDDIDLTFPGERRGELEAIVEMLGGRVMEELDYGFLAEIGDELLDCEPAWWADEAYEIAEAPQGSCPEAAEGVIAGRPVRCNSWEAIIWDYFYYADEVPPVDWPTKHIESYRLACTSLGAEKVEVLRAAFRSRYA 5cfu A 1.82 BS04 POP A 1 G28 R40 H42 D43 D44 D46 K147 H148 G26 R38 H40 D41 D42 D44 K145 H146 Q6X3H6 TTQVTLIHKILAAADERNLPLWIGGGWAIDARLGRVTRKHDDIDLTFPGERRGELEAIVEMLGGRVMEELDYGFLAEIGDELLDCEPAWWADEAYEIAEAPQGSCPEAAEGVIAGRPVRCNSWEAIIWDYFYYADEVPPVDWPTKHIESYRLACTSLGAEKVEVLRAAFRSRYA 5cfu A 1.82 BS05 POP A 2 D43 K147 D41 K145 Q6X3H6 TTQVTLIHKILAAADERNLPLWIGGGWAIDARLGRVTRKHDDIDLTFPGERRGELEAIVEMLGGRVMEELDYGFLAEIGDELLDCEPAWWADEAYEIAEAPQGSCPEAAEGVIAGRPVRCNSWEAIIWDYFYYADEVPPVDWPTKHIESYRLACTSLGAEKVEVLRAAFRSRYA 5cgb A 1.60 BS01 51C A 1 F1 I13 N46 D47 Y48 I52 D54 Q133 N135 Y137 N138 D140 F142 F1 I13 N46 D47 Y48 I52 D54 Q133 N135 Y137 N138 D140 F142 P08191 FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPT 5cgb B 1.60 BS01 51C B 1 F1 I13 N46 D47 Y48 I52 D54 Q133 N135 D140 F1 I13 N46 D47 Y48 I52 D54 Q133 N135 D140 P08191 FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPT 5chz A 1.83 BS01 NUC C 1 L447 V448 Q449 L466 R468 T469 S470 G471 Y540 D560 K562 L10 V11 Q12 L29 R31 T32 S33 G34 Y103 D123 K125 3.2.2.- O95243 WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL 5chz A 1.83 BS02 NUC D 1 R468 T469 K472 M473 K504 P505 L506 G507 L508 Y509 D510 L511 R31 T32 K35 M36 K67 P68 L69 G70 L71 Y72 D73 L74 3.2.2.- O95243 WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL 5chz A 1.83 BS03 NUC B 1 N467 R468 L534 H535 G536 I537 G538 K539 Y540 G541 D560 N30 R31 L97 H98 G99 I100 G101 K102 Y103 G104 D123 3.2.2.- O95243 WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL 5chz A 1.83 BS04 MG A 1 I532 L534 I537 I95 L97 I100 3.2.2.- O95243 WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL 5cik A 2.20 BS01 CIT A 1 P233 H234 H327 R328 H331 H338 E360 M362 R372 P231 H232 H325 R326 H329 H336 E358 M360 R370 3.4.13.9 Q8P839 TQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA 5cik B 2.20 BS01 CIT A 1 R72 F91 R70 F89 3.4.13.9 Q8P839 TQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA 5cik B 2.20 BS02 CIT B 1 P233 H327 R328 H331 H338 E360 M362 R372 P231 H325 R326 H329 H336 E358 M360 R370 3.4.13.9 Q8P839 TQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA 5cje A 2.50 BS01 HEM A 1 K64 L83 L84 H91 R95 F102 L230 A233 G234 T237 T238 L241 V280 A283 T284 R286 L309 A336 F337 G338 H342 C344 L345 G346 A350 K61 L80 L81 H88 R92 F99 L227 A230 G231 T234 T235 L238 V277 A280 T281 R283 L306 A333 F334 G335 H339 C341 L342 G343 A347 Q82LM3 VIDLGEYGARFTEDPYPVYAELRERGPVHWVRTPPPEAFEGWLVVGHEEARAALADPRLSKDGTKKGLTSLDVELMGPYLLVVDPPEHTRLRSLVARAFTMRRVEALRPRIQEITDGLLDEMLPRGRADLVDSFAYPLPITVICELLGVPDIDRVTFRALSNEIVAPTGGDAELAAYERLAAYLDELIDDKRSTAPADDLLGDLIRTRAEDDDRLSGEELRAMAFILLVAGHETTVNLITNGVHTLLTHPDQLAALRADMTLLDGAVEEVLRFEGPVETATYRYAAESMEIGGTAIAEGDPVMIGLDAAGRDPARHPDPHVFDIHRAPQGHLAFGHGIHYCLGAPLARLEARVALRSLLERCPDLALDGPPGARPPGMLIRGVRRLPVRW 5cjo A 3.29 BS01 III a 1 H332 G335 H336 G339 E341 L359 V360 G361 Q363 I374 Y609 H290 G293 H294 G297 E299 L317 V318 G319 Q321 I332 Y567 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINF 5cjo A 3.29 BS02 III a 2 Q111 H112 A140 F141 T142 E189 W199 T220 Y831 Q69 H70 A98 F99 T100 E147 W157 T178 Y789 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINF 5cjo A 3.29 BS03 ZN A 1 H108 H112 E189 H66 H70 E147 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINF 5ck6 A 2.50 BS01 3ZS A 1 N55 M78 L103 F134 N60 M83 L108 F139 3.3.2.8 Q9ZAG3 HHHHHHTSKIEQPRWASKDSAAGAASTPDEKIVLEFMDALTSNDAAKLIEYFAEDTMYQNMPLPPAYGRDAVEQTLAGLFTVMSYDAVETFHIGSSNGLVYTERVDVLRALPTGKSYNVSVLGVFQLTEGKITGWRDYFDLREFEEAVDLPLRG 5ck6 B 2.50 BS01 3ZS B 1 N55 M78 Y80 L103 F134 N52 M75 Y77 L100 F131 3.3.2.8 Q9ZAG3 KIEQPRWASKDSAAGAASTPDEKIVLEFMDALTSNDAAKLIEYFAEDTMYQNMPLPPAYGRDAVEQTLAGLFTVMSYDAVETFHIGSSNGLVYTERVDVLRALPTGKSYNVSVLGVFQLTEGKITGWRDYFDLREFEEAVDLPLRG 5clk A 2.70 BS01 3ZQ A 1 N55 M78 Y80 D101 L103 V116 D132 F134 N60 M83 Y85 D106 L108 V121 D137 F139 3.3.2.8 Q9ZAG3 HHHHHHTSKIEQPRWASKDSAAGAASTPDEKIVLEFMDALTSNDAAKLIEYFAEDTMYQNMPLPPAYGRDAVEQTLAGLFTVMSYDAVETFHIGSSNGLVYTERVDVLRALPTGKSYNVSVLGVFQLTEGKITGWRDYFDLREFEEAVDLPLRG 5clk B 2.70 BS01 3ZQ B 1 N55 Y80 D101 L103 D132 F134 N53 Y78 D99 L101 D130 F132 3.3.2.8 Q9ZAG3 SKIEQPRWASKDSAAGAASTPDEKIVLEFMDALTSNDAAKLIEYFAEDTMYQNMPLPPAYGRDAVEQTLAGLFTVMSYDAVETFHIGSSNGLVYTERVDVLRALPTGKSYNVSVLGVFQLTEGKITGWRDYFDLREFEEAVDLPLRG 5cmb A 1.34 BS01 GLY A 1 F63 D91 L92 S93 R98 K144 H145 E188 Y214 F59 D87 L88 S89 R94 K140 H141 E184 Y210 LIGRHLRLGSVEEQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSKHPETLLKTHRDSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSG 5cmb A 1.34 BS02 MG A 1 D110 E213 D106 E209 LIGRHLRLGSVEEQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSKHPETLLKTHRDSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSG 5cmb B 1.34 BS01 MG A 1 D110 E213 D110 E213 GSKNLIGRHLRLGSVEEQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSKHPETLLKTHRDSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSGNSVC 5cmb B 1.34 BS02 GLY B 1 F63 D91 L92 S93 R98 K144 H145 E188 Y214 F63 D91 L92 S93 R98 K144 H145 E188 Y214 GSKNLIGRHLRLGSVEEQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSKHPETLLKTHRDSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSGNSVC 5cmc A 1.28 BS01 GLY A 1 F63 D91 S93 R98 R144 H145 E188 F59 D87 S89 R94 R140 H141 E184 LIGRHLRLGSVESQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSRHPETLLKTHRDSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSG 5cmc A 1.28 BS02 MG B 1 D110 E213 D106 E209 LIGRHLRLGSVESQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSRHPETLLKTHRDSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSG 5cmc B 1.28 BS01 GLY B 1 F63 D91 S93 R98 R144 H145 E188 F63 D91 S93 R98 R144 H145 E188 GSKNLIGRHLRLGSVESQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSRHPETLLKTHRDSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSGNSVC 5cmc B 1.28 BS02 MG B 1 D110 E213 D110 E213 GSKNLIGRHLRLGSVESQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSRHPETLLKTHRDSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSGNSVC 5cmh A 1.61 BS01 HG A 1 C284 H305 Y309 C203 H219 Y223 2.4.1.40,2.4.1.37 P16442 EFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEDSHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 5cmk A 1.80 BS01 GLU A 1 Y61 P89 L90 T91 R96 G141 S142 T143 E191 Y217 Y59 P87 L88 T89 R94 G139 S140 T141 E189 Y215 P42260 NRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTSDYALLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWR 5cmk B 1.80 BS01 LY5 B 1 Y61 P89 L90 T91 R96 V138 G141 S142 T143 M190 E191 Y217 Y60 P88 L89 T90 R95 V137 G140 S141 T142 M189 E190 Y216 P42260 SNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTSDYALLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRG 5cmm A 1.27 BS01 SYM A 1 E13 Y61 P89 L90 T91 R96 V138 G141 S142 T143 S174 E191 Y217 E13 Y61 P89 L90 T91 R96 V138 G141 S142 T143 S174 E191 Y217 Q13002 GSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTSDYALLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGCPE 5cnx A 2.60 BS01 ZN A 1 D223 H292 E321 E335 D223 H292 E321 E335 3.4.11.- P76524 STLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISRESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSWETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHLLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLLTGE 5cnx A 2.60 BS02 ZN A 2 D212 D223 E335 D212 D223 E335 3.4.11.- P76524 STLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISRESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSWETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHLLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLLTGE 5cnx B 2.60 BS01 ZN B 1 D223 H292 E321 E335 D223 H292 E321 E335 3.4.11.- P76524 STLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISRESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSWETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHLLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLLTGE 5cnx B 2.60 BS02 ZN B 2 D212 D223 E335 D212 D223 E335 3.4.11.- P76524 STLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISRESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSWETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHLLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLLTGE 5cnx C 2.60 BS01 ZN C 1 D223 H292 E321 E335 D223 H292 E321 E335 3.4.11.- P76524 STLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISRESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSWETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHLLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLLTGE 5cnx C 2.60 BS02 ZN C 2 D212 D223 E335 D212 D223 E335 3.4.11.- P76524 STLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISRESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSWETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHLLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLLTGE 5co4 B 1.70 BS01 MTA B 1 F79 S80 A81 F100 G101 P102 E103 G106 L118 I120 M122 S128 L129 L131 A134 F92 S93 A94 F113 G114 P115 E116 G119 L131 I133 M135 S141 L142 L144 A147 2.1.1.207 Q72G96 HHHHLEVLFQGPHMLHLVLYQPEIPQNAGNVARTAAALGWPLHLIRPLGFLLSSPKLKRAGLDYWPHVDLRLHDSFAAFLEALPRGARVFAFSARGEASLYEARFREGDYLLFGPESRGLPEEVLARFPTLKIPMPGPVRSLNLAVAVGVAAYEAYRQLTG 5co4 A 1.70 BS01 MTA A 1 F79 S80 A81 F100 G101 P102 E103 G106 L118 I120 M122 L129 L131 A134 F82 S83 A84 F103 G104 P105 E106 G109 L121 I123 M125 L132 L134 A137 2.1.1.207 Q72G96 GPHMLHLVLYQPEIPQNAGNVARTAAALGWPLHLIRPLGFLLSSPKLKRAGLDYWPHVDLRLHDSFAAFLEALPRGARVFAFSARGEASLYEARFREGDYLLFGPESRGLPEEVLARFPTLKIPMPGPVRSLNLAVAVGVAAYEAYRQLTGR 5co5 A 2.10 BS01 III F 1 Y91 W145 V146 Y186 C188 C189 E191 Y193 Y92 W146 V147 Y187 C189 C190 E192 Y194 Q8WSF8 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5co5 A 2.10 BS02 III C 1 Y53 Q55 D75 R77 V106 T108 S112 M114 I116 D157 D162 S164 S165 Y54 Q56 D76 R78 V107 T109 S113 M115 I117 D158 D163 S165 S166 Q8WSF8 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5co5 B 2.10 BS01 III C 1 Y91 W145 Y186 C188 C189 E191 Y193 Y92 W146 Y187 C189 C190 E192 Y194 Q8WSF8 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5co5 B 2.10 BS02 III E 1 T34 Y53 Q55 R77 V106 S112 M114 I116 D157 D162 S164 S165 T35 Y54 Q56 R78 V107 S113 M115 I117 D158 D163 S165 S166 Q8WSF8 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5co5 D 2.10 BS01 III E 1 Y91 W145 V146 Y186 C188 C189 E191 Y193 Y92 W146 V147 Y187 C189 C190 E192 Y194 Q8WSF8 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5co5 D 2.10 BS02 III J 1 Y53 Q55 D75 R77 V106 T108 S112 M114 I116 D162 S164 Y54 Q56 D76 R78 V107 T109 S113 M115 I117 D163 S165 Q8WSF8 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5co5 G 2.10 BS01 III F 1 T34 Y53 Q55 R57 R77 V106 S112 M114 I116 D157 D162 S164 S165 T35 Y54 Q56 R58 R78 V107 S113 M115 I117 D158 D163 S165 S166 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5co5 G 2.10 BS02 III H 1 Y91 W145 V146 Y186 C188 C189 E191 Y193 Y92 W146 V147 Y187 C189 C190 E192 Y194 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5co5 I 2.10 BS01 III H 1 Y53 Q55 R57 R77 M114 I116 D162 S164 Y54 Q56 R58 R78 M115 I117 D163 S165 Q8WSF8 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5co5 I 2.10 BS02 III J 1 Y91 W145 Y186 C188 C189 E191 Y193 Y92 W146 Y187 C189 C190 E192 Y194 Q8WSF8 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5d4u A 2.00 BS01 SAM A 1 K34 G54 Y56 L57 W58 D77 I78 H79 L97 L117 T118 G122 I123 E139 G184 T185 K23 G43 Y45 L46 W47 D66 I67 H68 L86 L106 T107 G111 I112 E128 G173 T174 Q57913 27391308 EMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d4u B 2.00 BS01 SAM B 1 K34 G54 Y56 L57 W58 D77 I78 H79 M82 L117 T118 G122 I123 E139 G184 T185 F221 K23 G43 Y45 L46 W47 D66 I67 H68 M71 L106 T107 G111 I112 E128 G173 T174 F210 Q57913 27391308 EMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d4u C 2.00 BS01 SAM C 1 K34 G54 Y56 L57 W58 D77 I78 H79 M82 L117 T118 G122 I123 E139 G184 T185 K23 G43 Y45 L46 W47 D66 I67 H68 M71 L106 T107 G111 I112 E128 G173 T174 Q57913 27391308 EMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d4u D 2.00 BS01 SAM D 1 K34 G54 Y56 L57 W58 D77 I78 H79 M82 L97 L117 T118 G122 I123 E139 G184 T185 K23 G43 Y45 L46 W47 D66 I67 H68 M71 L86 L106 T107 G111 I112 E128 G173 T174 Q57913 27391308 EMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d4v A 1.60 BS01 SAH A 1 K34 G54 Y56 L57 W58 D77 I78 H79 M82 L97 L117 T118 I123 E139 G184 T185 K23 G43 Y45 L46 W47 D66 I67 H68 M71 L86 L106 T107 I112 E128 G173 T174 Q57913 27391308 EMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d4v B 1.60 BS01 SAH B 1 K34 G54 V55 Y56 L57 W58 D77 I78 H79 M82 L97 L117 T118 I123 E139 G184 T185 K26 G46 V47 Y48 L49 W50 D69 I70 H71 M74 L89 L109 T110 I115 E131 G176 T177 Q57913 27391308 GITEMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d4v B 1.60 BS02 YGP B 1 Y156 K157 A160 E266 Y148 K149 A152 E258 Q57913 27391308 GITEMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d4v C 1.60 BS01 SAH C 1 K34 G54 V55 Y56 L57 W58 D77 I78 H79 M82 L117 T118 I123 E139 G184 T185 F221 K26 G46 V47 Y48 L49 W50 D69 I70 H71 M74 L109 T110 I115 E131 G176 T177 F213 Q57913 27391308 GITEMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d4v C 1.60 BS02 YGP C 1 Y156 K157 A160 E266 Y148 K149 A152 E258 Q57913 27391308 GITEMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d4v D 1.60 BS01 SAH D 1 K34 G54 Y56 L57 W58 D77 I78 H79 M82 L97 L117 T118 G122 I123 E139 G184 T185 K23 G43 Y45 L46 W47 D66 I67 H68 M71 L86 L106 T107 G111 I112 E128 G173 T174 Q57913 27391308 EMVKTIDTKTRVVDVTNEIAKKKYQAIRDFLEGEEFKEVVIFGVYLWGNYTAQMLSKYADKVYLVDIHEFMKGFVPNNNSIKFLNLNEFKLKFIRGEVNPDLIVDLTGLGGIEPEFLAKFNPKVFIVEDPKGVFDVDIYEADNTYKRTAPFIEKAKVGVLKTYRKARVSKTSGTMTLTIDTIVDASREITSLDGVLYAIPNLRYYEGILFHENDIHKFLSEISQPAITISTLNDVLDEAEEILSNNINLIYSFVEEL 5d6r B 2.28 BS01 MG B 1 D447 D474 G476 D439 D466 G468 2.2.1.6 P27696 VRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITGKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPVTKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPVSGKVLPASPQMGAAPDDAIDQVAKLIAQAKNPIFLLGLMASQPENSKALRRLLETSHIPVTSTYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIGYSPVEYEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEILRDRQHQRELLDRRGAQLNQFALHPLRIVRAMQDIVNSDVTLTVDMGSFHIWIARYLYSFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKANVLHLIWVDNGYNMVAIQEEKKYQRLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTLRAAMDVDGPAVVAIPVDYRDNPLLMGQLHLS 5d6r B 2.28 BS02 MG B 2 S129 T132 S123 T126 2.2.1.6 P27696 VRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITGKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPVTKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPVSGKVLPASPQMGAAPDDAIDQVAKLIAQAKNPIFLLGLMASQPENSKALRRLLETSHIPVTSTYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIGYSPVEYEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEILRDRQHQRELLDRRGAQLNQFALHPLRIVRAMQDIVNSDVTLTVDMGSFHIWIARYLYSFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKANVLHLIWVDNGYNMVAIQEEKKYQRLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTLRAAMDVDGPAVVAIPVDYRDNPLLMGQLHLS 5d6r B 2.28 BS03 MG B 3 R69 Q220 P221 R63 Q212 P213 2.2.1.6 P27696 VRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITGKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPVTKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPVSGKVLPASPQMGAAPDDAIDQVAKLIAQAKNPIFLLGLMASQPENSKALRRLLETSHIPVTSTYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIGYSPVEYEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEILRDRQHQRELLDRRGAQLNQFALHPLRIVRAMQDIVNSDVTLTVDMGSFHIWIARYLYSFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKANVLHLIWVDNGYNMVAIQEEKKYQRLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTLRAAMDVDGPAVVAIPVDYRDNPLLMGQLHLS 5d6r B 2.28 BS04 EN0 B 1 M394 G395 S396 F397 Q420 M422 G446 D447 G448 G449 D474 G476 Y477 N478 M479 V480 Y543 M386 G387 S388 F389 Q412 M414 G438 D439 G440 G441 D466 G468 Y469 N470 M471 V472 Y535 2.2.1.6 P27696 VRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITGKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPVTKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPVSGKVLPASPQMGAAPDDAIDQVAKLIAQAKNPIFLLGLMASQPENSKALRRLLETSHIPVTSTYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIGYSPVEYEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEILRDRQHQRELLDRRGAQLNQFALHPLRIVRAMQDIVNSDVTLTVDMGSFHIWIARYLYSFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKANVLHLIWVDNGYNMVAIQEEKKYQRLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTLRAAMDVDGPAVVAIPVDYRDNPLLMGQLHLS 5d6r M 2.28 BS01 MG M 1 D447 D474 G476 D446 D473 G475 2.2.1.6 P27696 PRGSHMDKQYPVRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITGKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPVTKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPVSGKVLPASGAPQMGAAPDDAIDQVAKLIAQAKNPIFLLGLMASQPENSKALRRLLETSHIPVTSTYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIGYSPVEYEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEILRDRQHQRELQLNQFALHPLRIVRAMQDIVNSDVTLTVDMGSFHIWIARYLYSFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKANVLHLIWVDNGYNMVAIQEEKKYQRLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTLRAAMDVDGPAVVAIPVDYRDNPLLMGQLH 5d6r M 2.28 BS02 MG M 2 S129 T132 S134 T137 2.2.1.6 P27696 PRGSHMDKQYPVRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITGKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPVTKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPVSGKVLPASGAPQMGAAPDDAIDQVAKLIAQAKNPIFLLGLMASQPENSKALRRLLETSHIPVTSTYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIGYSPVEYEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEILRDRQHQRELQLNQFALHPLRIVRAMQDIVNSDVTLTVDMGSFHIWIARYLYSFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKANVLHLIWVDNGYNMVAIQEEKKYQRLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTLRAAMDVDGPAVVAIPVDYRDNPLLMGQLH 5d6r M 2.28 BS03 EN0 M 1 M394 G395 S396 F397 Q420 M422 G446 D447 G448 G449 D474 G476 Y477 N478 M479 V480 Q483 Y543 M393 G394 S395 F396 Q419 M421 G445 D446 G447 G448 D473 G475 Y476 N477 M478 V479 Q482 Y542 2.2.1.6 P27696 PRGSHMDKQYPVRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITGKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPVTKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPVSGKVLPASGAPQMGAAPDDAIDQVAKLIAQAKNPIFLLGLMASQPENSKALRRLLETSHIPVTSTYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIGYSPVEYEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEILRDRQHQRELQLNQFALHPLRIVRAMQDIVNSDVTLTVDMGSFHIWIARYLYSFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKANVLHLIWVDNGYNMVAIQEEKKYQRLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTLRAAMDVDGPAVVAIPVDYRDNPLLMGQLH 5djt A 1.40 BS01 FMN A 1 V416 T418 N425 N449 A450 R451 L453 Q454 V463 R467 I470 L480 N482 N492 F494 L496 F509 I510 G511 Q513 V14 T16 N23 N47 A48 R49 L51 Q52 V61 R65 I68 L78 N80 N90 F92 L94 F107 I108 G109 Q111 O49004 SLATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNARFLQGPETDRATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDAAEREGVMLIKKTAENIDEAAKEL 5dju A 2.10 BS01 FMN A 1 V416 T418 N425 N449 A450 R451 L453 Q454 V463 R467 I470 L480 N482 N492 F494 F509 I510 G511 Q513 V15 T17 N24 N48 A49 R50 L52 Q53 V62 R66 I69 L79 N81 N91 F93 F108 I109 G110 Q112 O49004 GSLATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNARFLQGPETDRATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDAAEREGVMLIKKTAENIDEAAKEL 5dju C 2.10 BS01 FMN C 1 V416 T418 N425 N449 A450 R451 L453 Q454 V463 I466 R467 I470 L480 N482 N492 F494 F509 G511 Q513 V15 T17 N24 N48 A49 R50 L52 Q53 V62 I65 R66 I69 L79 N81 N91 F93 F108 G110 Q112 O49004 GSLATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNARFLQGPETDRATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDAAEREGVMLIKKTAENIDEAAKEL 5dn2 A 1.95 BS01 III G 1 Y299 S300 T319 D323 S349 T352 Y356 G417 I418 Y26 S27 T46 D50 S76 T79 Y83 G144 I145 O60462 26991001 MFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 5dn2 C 1.95 BS01 III E 1 Y299 S300 W304 T319 D323 S349 E351 T352 Y356 G417 I418 Y26 S27 W31 T46 D50 S76 E78 T79 Y83 G144 I145 O60462 26991001 MFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 5dn2 D 1.95 BS01 III F 1 Y299 W304 T319 D323 S349 E351 T352 Y356 G417 I418 Y26 W31 T46 D50 S76 E78 T79 Y83 G144 I145 O60462 26991001 MFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 5dn3 A 2.05 BS01 MG A 1 N261 D274 N137 D150 2.7.11.1 O14965 27339427 KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 5dn3 A 2.05 BS02 5DN A 1 K166 L169 E175 L178 V182 Y199 H201 K42 L45 E51 L54 V58 Y75 H77 2.7.11.1 O14965 27339427 KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 5dn3 A 2.05 BS03 ATP A 1 L139 G140 K141 G142 K143 V147 A160 K162 E181 L194 E211 A213 T217 E260 N261 L263 D274 G276 L15 G16 K17 G18 K19 V23 A36 K38 E57 L70 E87 A89 T93 E136 N137 L139 D150 G152 2.7.11.1 O14965 27339427 KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 5dnr A 1.95 BS01 MG A 1 N261 D274 N136 D149 2.7.11.1 O14965 27339427 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dnr A 1.95 BS02 ATP A 1 L139 G140 K141 G142 K143 V147 A160 K162 E181 L194 E211 A213 T217 N261 L263 D274 G276 L14 G15 K16 G17 K18 V22 A35 K37 E56 L69 E86 A88 T92 N136 L138 D149 G151 2.7.11.1 O14965 27339427 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dnr A 1.95 BS03 MG A 2 K162 E181 K37 E56 2.7.11.1 O14965 27339427 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dos A 2.98 BS01 MG A 1 E260 N261 D274 E134 N135 D148 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dos A 2.98 BS02 5DN A 1 K166 E175 L178 R179 V182 Y199 H201 V206 K40 E49 L52 R53 V56 Y73 H75 V80 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dos A 2.98 BS03 ATP A 1 L139 G140 K141 G142 K143 V147 A160 K162 E181 L194 E211 Y212 A213 T217 N261 L263 D274 L13 G14 K15 G16 K17 V21 A34 K36 E55 L68 E85 Y86 A87 T91 N135 L137 D148 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dpv A 2.29 BS01 5DN A 1 K166 L169 E175 L178 R179 V182 Y199 H201 V206 K40 L43 E49 L52 R53 V56 Y73 H75 V80 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 5dpv A 2.29 BS02 SKE A 1 R137 L139 G140 V147 A160 E211 Y212 A213 G216 T217 R220 E260 L263 R11 L13 G14 V21 A34 E85 Y86 A87 G90 T91 R94 E134 L137 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 5dr2 A 2.46 BS01 5E1 A 1 K166 L169 E170 E175 L178 R179 V182 Y199 H201 V206 K40 L43 E44 E49 L52 R53 V56 Y73 H75 V80 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRATLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dr2 A 2.46 BS02 MG A 1 E260 N261 D274 E134 N135 D148 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRATLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dr2 A 2.46 BS03 ATP A 1 G140 K141 G142 K143 F144 V147 A160 K162 E181 L194 E211 A213 T217 E260 N261 L263 D274 G276 G14 K15 G16 K17 F18 V21 A34 K36 E55 L68 E85 A87 T91 E134 N135 L137 D148 G150 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRATLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dr6 A 2.53 BS01 5E1 A 1 K166 E170 E175 L178 R179 V182 Y199 H201 V206 K40 E44 E49 L52 R53 V56 Y73 H75 V80 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dr6 A 2.53 BS02 SKE A 1 R137 L139 G140 V147 A160 E211 Y212 A213 G216 R220 E260 L263 R11 L13 G14 V21 A34 E85 Y86 A87 G90 R94 E134 L137 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dr9 A 2.47 BS01 SKE A 1 R137 L139 G140 V147 A160 L194 L210 E211 A213 G216 R220 E260 L263 R11 L13 G14 V21 A34 L68 L84 E85 A87 G90 R94 E134 L137 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dr9 A 2.47 BS02 5E2 A 1 K166 E170 E175 L178 R179 V182 Y199 H201 V206 K40 E44 E49 L52 R53 V56 Y73 H75 V80 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5drd A 2.13 BS01 MG A 1 N261 D274 N135 D148 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5drd A 2.13 BS02 ATP A 1 L139 G140 K141 G142 K143 F144 G145 V147 A160 K162 E181 L194 E211 A213 T217 E260 N261 L263 D274 L13 G14 K15 G16 K17 F18 G19 V21 A34 K36 E55 L68 E85 A87 T91 E134 N135 L137 D148 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dt0 A 2.15 BS01 SKE A 1 R137 L139 G140 V147 A160 L194 L210 E211 Y212 A213 G216 R220 E260 L263 A273 R11 L13 G14 V21 A34 L68 L84 E85 Y86 A87 G90 R94 E134 L137 A147 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dt3 A 2.33 BS01 MG A 1 N261 D274 N135 D148 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dt3 A 2.33 BS02 ATP A 1 L139 G140 K141 G142 K143 V147 A160 K162 E181 L194 E211 A213 T217 E260 N261 L263 D274 G276 L13 G14 K15 G16 K17 V21 A34 K36 E55 L68 E85 A87 T91 E134 N135 L137 D148 G150 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dt4 A 2.86 BS01 MG A 1 N261 D274 N135 D148 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dt4 A 2.86 BS02 5DN A 1 K166 L169 E170 E175 L178 R179 Y199 H201 V206 K40 L43 E44 E49 L52 R53 Y73 H75 V80 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dt4 A 2.86 BS03 ATP A 1 L139 G140 K141 G142 K143 F144 V147 A160 K162 E181 L194 E211 A213 T217 E260 N261 L263 D274 G276 L13 G14 K15 G16 K17 F18 V21 A34 K36 E55 L68 E85 A87 T91 E134 N135 L137 D148 G150 2.7.11.1 O14965 27339427 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5dx3 A 2.09 BS01 III C 1 I358 K362 F367 L372 Q375 V376 L379 E380 D538 L539 E542 M543 I52 K56 F61 L66 Q69 V70 L73 E74 D222 L223 E226 M227 P03372 26928945 ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAH 5dx3 A 2.09 BS02 EST A 1 M343 L346 L349 A350 E353 L387 R394 H524 L525 M37 L40 L43 A44 E47 L81 R88 H208 L209 P03372 26928945 ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAH 5dx3 B 2.09 BS01 III D 1 I358 K362 F367 L372 Q375 V376 L379 E380 L539 M543 I45 K49 F54 L59 Q62 V63 L66 E67 L215 M219 P03372 26928945 LSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKMVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5dx3 B 2.09 BS02 EST B 1 L346 E353 L387 M388 R394 F404 M421 H524 L525 L33 E40 L74 M75 R81 F91 M108 H200 L201 P03372 26928945 LSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKMVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5e3t A 3.30 BS01 ANP A 1 S158 F160 I169 K171 N222 N223 L224 D236 K238 T257 D299 L303 D378 S98 F100 I109 K111 N162 N163 L164 D176 K178 T197 D239 L243 D272 Q503I3 TTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILHMGGIPAFNSKGERLLVFIGIIDILQSYRSVHRPSFYADRFQKFMCSTVFRKS 5e3t A 3.30 BS02 MN A 1 D299 D378 D239 D272 Q503I3 TTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILHMGGIPAFNSKGERLLVFIGIIDILQSYRSVHRPSFYADRFQKFMCSTVFRKS 5e3t A 3.30 BS03 MN A 2 D299 S301 D378 D239 S241 D272 Q503I3 TTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILHMGGIPAFNSKGERLLVFIGIIDILQSYRSVHRPSFYADRFQKFMCSTVFRKS 5e3u A 3.60 BS01 ANP A 1 G157 F160 I169 K171 N222 N223 L224 D236 T257 L303 D378 G97 F100 I109 K111 N162 N163 L164 D176 T197 L243 D272 Q503I3 TTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILHMGGIPAFNSKGERLLVFIGIIDILQSYRSVHRPSFYADRFQKFMCSTVFRKS 5e3u A 3.60 BS02 MN A 1 D299 D378 Q381 D239 D272 Q275 Q503I3 TTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILHMGGIPAFNSKGERLLVFIGIIDILQSYRSVHRPSFYADRFQKFMCSTVFRKS 5e3u A 3.60 BS03 MN A 2 D299 S301 D378 D239 S241 D272 Q503I3 TTSSALKGAIQLGITHSVGSLSQKPERDVLMQDFEVVESIFFPSQGSSSTPGHHHGDFKFKTYAPIAFRYFREMFGIRPDDYLYSLCNEPLIELSNGSLFYVSSDDEFIIKTVQHKEAEFLQTLLPGYFMNLNQNMRTLLPKFYGLYCVQADGKNIRIVVMNNLLPRAVPMHLKFDLKGSTYKRRASPKERSKGVPTYKDLDFMQDMPEGILLENDHYTALSRTMQRDCRVLQSFKIMDYSLLVGIHILHMGGIPAFNSKGERLLVFIGIIDILQSYRSVHRPSFYADRFQKFMCSTVFRKS 5e6m A 2.93 BS01 NUC C 1 P234 M238 K255 R256 E259 K264 E429 Y512 V513 P148 M152 K169 R170 E173 K178 E340 Y353 V354 6.1.1.14 P41250 27261259 EEVLAPLRLAVRQQGDLVRKLKEDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETG 5e6m A 2.93 BS02 NUC E 1 R67 D72 R76 Q82 G88 G89 S91 H140 F144 L226 P244 R277 I280 S281 R283 R288 D545 Q547 R548 L567 S568 Q569 N570 S599 I600 G601 R602 Y604 A605 R606 E609 T617 D619 F620 T631 R633 M638 Q640 F672 Q675 R55 D60 R64 Q70 G76 G77 S79 H128 F132 L140 P158 R191 I194 S195 R197 R202 D386 Q388 R389 L408 S409 Q410 N411 S440 I441 G442 R443 Y445 A446 R447 E450 T458 D460 F461 T472 R474 M479 Q481 F513 Q516 6.1.1.14 P41250 27261259 EEVLAPLRLAVRQQGDLVRKLKEDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETG 5e6m A 2.93 BS03 GAP A 1 E245 R277 E279 I287 R288 V289 F292 M294 E296 E403 I404 G406 E522 S524 G526 R529 E159 R191 E193 I201 R202 V203 F206 M208 E210 E314 I315 G317 E363 S365 G367 R370 6.1.1.14 P41250 27261259 EEVLAPLRLAVRQQGDLVRKLKEDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETG 5e6m B 2.93 BS01 NUC C 1 R67 D72 R76 Q82 G88 G89 V90 S91 H140 F144 L226 P244 E245 R277 I280 S281 R283 R288 Q547 R548 L567 S568 N570 S597 S599 I600 G601 R602 Y604 A605 R606 E609 T617 D619 F620 T631 R633 M638 Q640 F672 Q675 R4 D9 R13 Q19 G25 G26 V27 S28 H77 F81 L123 P141 E142 R174 I177 S178 R180 R185 Q375 R376 L395 S396 N398 S425 S427 I428 G429 R430 Y432 A433 R434 E437 T445 D447 F448 T459 R461 M466 Q468 F500 Q503 6.1.1.14 P41250 27261259 IVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETG 5e6m B 2.93 BS02 NUC E 1 P234 K255 R256 E259 Q262 K264 E429 Y512 V513 P131 K152 R153 E156 Q159 K161 E324 Y340 V341 6.1.1.14 P41250 27261259 IVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETG 5e6m B 2.93 BS03 GAP B 1 E245 R277 L286 I287 R288 V289 F292 E296 E403 I404 E522 S524 G526 R529 E142 R174 L183 I184 R185 V186 F189 E193 E298 I299 E350 S352 G354 R357 6.1.1.14 P41250 27261259 IVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETG 5e83 A 1.80 BS01 HEM A 1 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 N97 F98 L101 L136 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 N97 F98 L101 L136 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 5e83 A 1.80 BS02 5L7 A 1 V1 P77 A130 S131 T134 V135 V1 P77 A130 S131 T134 V135 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 5e83 B 1.80 BS01 HEM B 1 T38 F41 F42 H63 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 T38 F41 F42 H63 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 P68871 VHLTPVEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 5e83 C 1.80 BS01 5L7 A 1 V1 S131 T134 V1 S131 T134 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 5e83 C 1.80 BS02 HEM C 1 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 5e83 D 1.80 BS01 HEM D 1 T38 F41 F42 F45 H63 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 T38 F41 F42 F45 H63 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 P68871 VHLTPVEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 5efw A 2.10 BS01 FMN A 1 V416 T418 N425 N449 A450 R451 L453 Q454 V463 I466 R467 I470 L480 N482 N492 F494 L496 F509 I510 G511 Q513 V11 T13 N20 N44 A45 R46 L48 Q49 V58 I61 R62 I65 L75 N77 N87 F89 L91 F104 I105 G106 Q108 O49003 TTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNARFLQGPETDRATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDAAEREGVMLIKKTAENIDEAAKEL 5ete A 2.10 BS01 DIO A 1 N236 Y237 D238 G243 F244 S245 N79 Y80 D81 G86 F87 S88 A0A0C6AG41 27344972 DLSDFASSVLAEHNKKRALHKDTPALSWSDTLASYAQDYADNYDCSGTLTHSGGPYGENLALGYDGPAAVDAWYNEISNYDFSNPGFSSNTGHFTQVVWKSTTQVGCGIKTCGGAWGDYVICSYDPAGNYEGEYADNVEPLA 5ete A 2.10 BS02 DIO A 2 L189 Y213 Q261 L32 Y56 Q104 A0A0C6AG41 27344972 DLSDFASSVLAEHNKKRALHKDTPALSWSDTLASYAQDYADNYDCSGTLTHSGGPYGENLALGYDGPAAVDAWYNEISNYDFSNPGFSSNTGHFTQVVWKSTTQVGCGIKTCGGAWGDYVICSYDPAGNYEGEYADNVEPLA 5ete A 2.10 BS03 DIO A 3 G211 P212 Y213 A284 Y287 G54 P55 Y56 A127 Y130 A0A0C6AG41 27344972 DLSDFASSVLAEHNKKRALHKDTPALSWSDTLASYAQDYADNYDCSGTLTHSGGPYGENLALGYDGPAAVDAWYNEISNYDFSNPGFSSNTGHFTQVVWKSTTQVGCGIKTCGGAWGDYVICSYDPAGNYEGEYADNVEPLA 5eyp A 1.90 BS01 GTP A 1 G10 Q11 A12 Q15 I16 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 S178 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 I16 D89 A90 N92 S131 G134 G135 T136 G137 I162 V168 S169 E174 N197 Y215 N219 I222 D0VWZ0 27380724 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 5eyp A 1.90 BS02 LOC B 1 S178 T179 A180 V181 S169 T170 A171 V172 D0VWZ0 27380724 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 5eyp B 1.90 BS01 GDP B 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 P173 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 P171 V175 D177 E181 N204 Y222 N226 D0VWY9 27380724 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5eyp B 1.90 BS02 LOC B 1 C241 L242 L248 A250 K254 L255 N258 M259 T314 V315 A316 I318 N350 K352 A354 I378 C239 L240 L246 A248 K252 L253 N256 M257 T306 V307 A308 I310 N342 K344 A346 I362 D0VWY9 27380724 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5ezt X 1.54 BS01 ZN X 1 H93 H95 H118 H91 H93 H116 4.2.1.1 P00921 27292012 HWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSRRMVNNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHLVHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDPGSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLMLANWRPAQPLKNRQVRGFPK 5f84 A 2.50 BS01 UDP A 1 I200 R229 G230 S231 T233 R237 E275 V276 F278 G292 S296 R298 I159 R188 G189 S190 T192 R196 E234 V235 F237 G251 S255 R257 2.4.1.- Q8T045 NEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGP 5f84 A 2.50 BS02 BGC B 1 D151 W184 V293 A294 A295 S296 F297 D110 W143 V252 A253 A254 S255 F256 2.4.1.- Q8T045 NEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGP 5f85 A 2.15 BS01 UDP A 1 P191 I200 R229 G230 S231 T233 R237 E275 V276 F278 G292 S296 R298 P150 I159 R188 G189 S190 T192 R196 E234 V235 F237 G251 S255 R257 2.4.1.- Q8T045 NEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGP 5f87 A 3.20 BS01 UDP A 1 P191 R229 G230 S231 T233 R237 E275 V276 F278 G292 S296 F297 R298 P150 R188 G189 S190 T192 R196 E234 V235 F237 G251 S255 F256 R257 2.4.1.- Q8T045 NEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGP 5f87 B 3.20 BS01 UDP B 1 P191 R229 G230 S231 T233 R237 E275 V276 F278 G292 S296 F297 R298 P150 R188 G189 S190 T192 R196 E234 V235 F237 G251 S255 F256 R257 2.4.1.- Q8T045 NEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGP 5f87 C 3.20 BS01 UDP C 1 P191 R229 G230 S231 T233 R237 E275 V276 F278 G292 S296 F297 R298 P150 R188 G189 S190 T192 R196 E234 V235 F237 G251 S255 F256 R257 2.4.1.- Q8T045 NEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGP 5f87 D 3.20 BS01 UDP D 1 P191 R229 G230 S231 T233 R237 E275 V276 F278 S296 R298 P150 R188 G189 S190 T192 R196 E234 V235 F237 S255 R257 2.4.1.- Q8T045 NEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGP 5f87 E 3.20 BS01 UDP E 1 R229 G230 S231 T233 R237 E275 V276 F278 G292 S296 F297 R298 R188 G189 S190 T192 R196 E234 V235 F237 G251 S255 F256 R257 2.4.1.- Q8T045 NEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGP 5f87 F 3.20 BS01 UDP F 1 R229 G230 S231 T233 R237 E275 V276 F278 G292 S296 F297 R298 R188 G189 S190 T192 R196 E234 V235 F237 G251 S255 F256 R257 2.4.1.- Q8T045 NEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSARYGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATKLHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGP 5fgs B 2.00 BS01 ZN B 1 D248 K249 D73 K74 C7T9P4 27349405 TTYERTFVKKDAETKEVLEGAGFKISNSDGKFLKLTDKDGQSVSIGEGFIDVLANNYRLTWVAESDATVFTSDKSGKFGLNGFADNTTTYTAVETNVPDGYDAAANTDFKADNSSSDILDAPS 5fgs D 2.00 BS01 ZN D 1 K185 D292 K10 D117 27349405 TTYERTFVKKDAETKEVLEGAGFKISNSDGKFLKLTDKDGQSVSIGEGFIDVLANNYRLTWVAESDATVFTSDKSGKFGLNGFADNTTTYTAVETNVPDGYDAAANTDFKADNSSSDILDAPS 5fgs D 2.00 BS02 ZN D 2 D212 Q216 D37 Q41 27349405 TTYERTFVKKDAETKEVLEGAGFKISNSDGKFLKLTDKDGQSVSIGEGFIDVLANNYRLTWVAESDATVFTSDKSGKFGLNGFADNTTTYTAVETNVPDGYDAAANTDFKADNSSSDILDAPS 5fra A 2.00 BS01 SIA A 1 I46 Y65 E74 R76 R153 N158 Y160 I54 Y73 E82 R84 R161 N166 Y168 A0A0H2YQR1 27208171 SPDPNWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fra B 2.00 BS01 SIA B 1 Y61 Y65 E74 R76 R153 N158 Y160 Y66 Y70 E79 R81 R158 N163 Y165 A0A0H2YQR1 27208171 PNWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fra C 2.00 BS01 SIA C 1 Y61 Y65 E74 R76 H93 R153 N158 Y160 Y66 Y70 E79 R81 H98 R158 N163 Y165 A0A0H2YQR1 27208171 PNWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fra D 2.00 BS01 SIA D 1 I46 Y65 E74 R76 R153 N158 Y160 I51 Y70 E79 R81 R158 N163 Y165 A0A0H2YQR1 27208171 PNWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fra E 2.00 BS01 SIA E 1 I46 Y65 E74 R76 R153 N158 Y160 I50 Y69 E78 R80 R157 N162 Y164 A0A0H2YQR1 27208171 NWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fra F 2.00 BS01 SIA F 1 I46 Y61 Y65 E74 R76 R153 N158 Y160 I50 Y65 Y69 E78 R80 R157 N162 Y164 A0A0H2YQR1 27208171 NWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre A 1.90 BS01 SIA A 1 I46 Y65 E74 R76 R153 N158 Y160 I51 Y70 E79 R81 R158 N163 Y165 A0A0H2YQR1 27208171 PNWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre A 1.90 BS02 CA A 1 N40 S41 D102 N45 S46 D107 A0A0H2YQR1 27208171 PNWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre A 1.90 BS03 CA A 2 D131 N133 D136 N138 A0A0H2YQR1 27208171 PNWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre A 1.90 BS04 CA A 3 N152 R153 E159 N157 R158 E164 A0A0H2YQR1 27208171 PNWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre B 1.90 BS01 SIA B 1 I46 Y65 E74 R76 R153 N158 Y160 I50 Y69 E78 R80 R157 N162 Y164 A0A0H2YQR1 27208171 NWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre B 1.90 BS02 CA B 1 N152 R153 E159 N156 R157 E163 A0A0H2YQR1 27208171 NWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre B 1.90 BS03 CA B 2 N40 S41 D102 N44 S45 D106 A0A0H2YQR1 27208171 NWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre B 1.90 BS04 CA B 3 D131 N133 D135 N137 A0A0H2YQR1 27208171 NWELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre C 1.90 BS01 SIA C 1 I46 Y65 E74 R76 R153 N158 Y160 I48 Y67 E76 R78 R155 N160 Y162 A0A0H2YQR1 27208171 WELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre C 1.90 BS02 CA C 1 N40 S41 D102 N43 S44 D104 A0A0H2YQR1 27208171 WELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fre C 1.90 BS03 CA C 2 N152 R153 E159 N154 R155 E161 A0A0H2YQR1 27208171 WELLSSLGEYKDINLESSNASNITYDLEKYKNLDEGTIVVRFNSDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQNGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKMIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETK 5fsi A 1.63 BS01 8DG A 1 Y7 T8 L9 F27 N33 G36 G37 K38 F72 M81 W117 D119 D120 W123 Y5 T6 L7 F25 N31 G34 G35 K36 F70 M79 W115 D117 D118 W121 3.6.1.55,3.6.1.56 P36639 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 5fsk A 1.56 BS01 H6Y A 1 Y7 F27 G28 N33 G36 G37 K38 E52 E56 F72 M81 W117 D119 D120 Y5 F25 G26 N31 G34 G35 K36 E50 E54 F70 M79 W115 D117 D118 3.6.1.55,3.6.1.56 P36639 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 5fsl A 1.25 BS01 UAN A 1 N33 F72 F74 W117 D119 D120 W123 N31 F70 F72 W115 D117 D118 W121 3.6.1.55,3.6.1.56 P36639 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 5fsm A 1.67 BS01 N91 A 1 L9 F27 N33 G34 F72 M81 W117 D119 D120 W123 F124 L7 F25 N31 G32 F70 M79 W115 D117 D118 W121 F122 3.6.1.55,3.6.1.56 P36639 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 5fsn A 1.69 BS01 6Q3 A 1 T8 F27 G36 F72 F74 M81 W117 D119 D120 F139 T6 F25 G34 F70 F72 M79 W115 D117 D118 F137 3.6.1.55,3.6.1.56 P36639 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 5fw5 A 1.92 BS01 III C 1 P6 L10 V11 E14 F15 R17 Q18 T21 L22 Q25 M29 R32 F33 E117 N122 K123 F124 P7 L11 V12 E15 F16 R18 Q19 T22 L23 Q26 M30 R33 F34 E118 N123 K124 F125 3.6.4.12,3.6.4.13 Q13283 27383630 SMVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF 5fws A 1.90 BS01 CA A 1 Y234 D263 D266 D306 N309 Y200 D229 D232 D272 N275 Q96MU8 PECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK 5fwt A 2.10 BS01 CA A 1 Y234 D263 D266 D306 N309 Y205 D234 D237 D277 N280 Q96MU8 PECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK 5fww B 3.50 BS01 CA B 1 Y234 T236 D266 S305 D306 N309 Y200 T202 D232 S271 D272 N275 Q96MU8 PECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK 5g4b A 2.24 BS01 PZE A 1 M135 E136 K138 Y183 W250 M20 E21 K23 Y68 W135 3.4.21.90 Q86925 DRTFAVKNEDGKIMGYAVAMEGKVIKPLHVKGTIDHPALAKLKFTKSSSYDMEFAKLPTEMKSDAFGYTTEHPEGFYNWHHGAVQFSGGRFTIPTGAGGPGDSGRPILDNSGKVVAIVLGGANEGARTALSVVTWNKKGAAIKTTHEDTVEW 5gjb A 1.70 BS01 NUC B 1 T225 R226 T245 C262 A264 T265 D291 S365 V366 S387 R388 T409 D410 I411 L430 K431 P432 L442 H486 K537 D540 R598 T48 R49 T68 C85 A87 T88 D114 S188 V189 S210 R211 T232 D233 I234 L253 K254 P255 L265 H309 K360 D363 R421 A0A142DS38 CFEPSMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAPTRVVAAEMEEALRGLPVRYMTTAVNVTHSGTEIVDLMCHATFTSRLLQPIRVPNYNLYIMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEVPERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKTKHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQRRGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIMEDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKR 5gjc A 2.20 BS01 MN A 1 T201 D285 E286 T20 D97 E98 A0A142DS38 SMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAPTRVVAAEMEEALRGLPVRYMTTGTEIVDLMCHATFTSRLLQPIRVPNYNLYIMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEVPERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKTKHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQRRGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIMEDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKR 5gjc A 2.20 BS02 ATP A 1 P196 G197 A198 G199 K200 T201 R202 E286 N330 R459 R462 P15 G16 A17 G18 K19 T20 R21 E98 N142 R271 R274 A0A142DS38 SMLKKKQLTVLDLHPGAGKTRRVLPEIVREAIKTRLRTVILAPTRVVAAEMEEALRGLPVRYMTTGTEIVDLMCHATFTSRLLQPIRVPNYNLYIMDEAHFTDPSSIAARGYISTRVEMGEAAAIFMTATPPGTRDAFPDSNSPIMDTEVEVPERAWSSGFDWVTDHSGKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETEFQKTKHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQRRGRIGRNPNKPGDEYLYGGGCAETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMKRGDLPVWLAYQVASAGITYTDRRWCFDGTTNNTIMEDSVPAEVWTRHGEKRVLKPRWMDARVCSDHAALKSFKEFAAGKR 5hct A 1.36 BS01 61P A 1 D33 D35 Y79 G80 D81 F116 D219 G221 T222 Y226 I300 D33 D35 Y79 G80 D81 F116 D219 G221 T222 Y226 I300 3.4.23.22 P11838 27400756 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 5hin A 1.60 BS01 FMN A 1 A95 A96 G97 K100 S120 N145 Y147 N181 N212 K255 T283 N284 T285 S305 G306 L309 V333 G334 G335 L355 Y356 T357 A64 A65 G66 K69 S89 N114 Y116 N150 N181 K224 T252 N253 T254 S274 G275 L278 V302 G303 G304 L324 Y325 T326 1.3.5.2 Q02127 TGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR 5hin A 1.60 BS02 1KL A 1 Y38 M43 L46 H56 L58 A59 F62 L67 L68 P69 F98 Y356 L359 T360 P364 Y7 M12 L15 H25 L27 A28 F31 L36 L37 P38 F67 Y325 L328 T329 P333 1.3.5.2 Q02127 TGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR 5hyp A 3.02 BS01 III B 1 V38 R39 S40 H41 S42 K63 R64 C65 R66 H67 E70 L82 V39 R40 S41 H42 S43 K64 R65 C66 R67 H68 E71 L83 P04003 SNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 5hyt B 2.54 BS01 III A 1 R39 S40 H41 S42 I61 R64 R66 H67 R39 S40 H41 S42 I61 R64 R66 H67 P04003 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 5hyt B 2.54 BS02 III C 1 S42 R64 I78 T80 L82 S42 R64 I78 T80 L82 P04003 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 5hyt D 2.54 BS01 III A 1 R64 I78 K79 T80 L82 R65 I79 K80 T81 L83 P04003 SNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 5hyt D 2.54 BS02 III C 1 T7 L8 L34 P35 Y62 R66 H67 E70 T8 L9 L35 P36 Y63 R67 H68 E71 P04003 SNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 5hyt F 2.54 BS01 III G 1 R64 I78 K79 T80 L82 R64 I78 K79 T80 L82 P04003 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 5hyt F 2.54 BS02 III E 1 T7 L34 P35 Y62 R64 R66 H67 E70 L82 T7 L34 P35 Y62 R64 R66 H67 E70 L82 P04003 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 5hyt H 2.54 BS01 III G 1 R39 S40 S42 I61 R64 R66 H67 E70 L82 R40 S41 S43 I62 R65 R67 H68 E71 L83 P04003 SNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 5hyt H 2.54 BS02 III E 1 R64 I78 K79 T80 L82 R65 I79 K80 T81 L83 P04003 SNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 5hzr A 2.33 BS01 KH2 A 1 N865 D866 R870 Y1090 V1099 N355 D356 R360 Y518 V527 G2QDW1 ANDEEAYLKLLDQAKDTRITHLLRQTDGFLKQLASSIDYYAVAHRIKEEVTEQASILVGGTLKEYQLKGLQWMLSLYNNNLNGILADEMGLGKTIQTISLITYLIEKKHQQGPYLVIVPLSTLTNWNLEFDKWAPSVAKVVYKGPPNARKMQQEKIRQGKFQVLLTTYEYIIKDRPLLSKIKWFHMIIDEGHRMSKLSATIQQYYSTRFRLILTGTPLQNNLAELWAMLNFVLPNIFKSAKTFDEWFNTPFAQDKMELTEEEQILVIRRLHKVLRPFLLRRLKKDVEKDLPDKTEKVIKCKFSALQARLYKQMVTHQKIAARGLSNMIMQLRKLCNHPFVFDEVENQMNPANVSNDLLWRTAGKFELLDRILPKYKATGHRVLMFFQMTAIMDIMEDFLRFRGLHYLRLDGTTKSEDRSELLRQFNQPDSPYFMFLLSTRALNLQTADTVIIYDSDIGQKNEVRILRLISSASVEEKILEGEQEEMDDDELNMILARNEEELAIFQKLDEERSRDPIYGTAPGCQGVPRLMTEDELPDIYLPVEEEVEMALG 5hzr A 2.33 BS02 KH2 A 2 Y569 N570 Q602 Y77 N78 Q110 G2QDW1 ANDEEAYLKLLDQAKDTRITHLLRQTDGFLKQLASSIDYYAVAHRIKEEVTEQASILVGGTLKEYQLKGLQWMLSLYNNNLNGILADEMGLGKTIQTISLITYLIEKKHQQGPYLVIVPLSTLTNWNLEFDKWAPSVAKVVYKGPPNARKMQQEKIRQGKFQVLLTTYEYIIKDRPLLSKIKWFHMIIDEGHRMSKLSATIQQYYSTRFRLILTGTPLQNNLAELWAMLNFVLPNIFKSAKTFDEWFNTPFAQDKMELTEEEQILVIRRLHKVLRPFLLRRLKKDVEKDLPDKTEKVIKCKFSALQARLYKQMVTHQKIAARGLSNMIMQLRKLCNHPFVFDEVENQMNPANVSNDLLWRTAGKFELLDRILPKYKATGHRVLMFFQMTAIMDIMEDFLRFRGLHYLRLDGTTKSEDRSELLRQFNQPDSPYFMFLLSTRALNLQTADTVIIYDSDIGQKNEVRILRLISSASVEEKILEGEQEEMDDDELNMILARNEEELAIFQKLDEERSRDPIYGTAPGCQGVPRLMTEDELPDIYLPVEEEVEMALG 5hzr A 2.33 BS03 KH2 A 3 R768 R769 K772 R775 R268 R269 K272 R275 G2QDW1 ANDEEAYLKLLDQAKDTRITHLLRQTDGFLKQLASSIDYYAVAHRIKEEVTEQASILVGGTLKEYQLKGLQWMLSLYNNNLNGILADEMGLGKTIQTISLITYLIEKKHQQGPYLVIVPLSTLTNWNLEFDKWAPSVAKVVYKGPPNARKMQQEKIRQGKFQVLLTTYEYIIKDRPLLSKIKWFHMIIDEGHRMSKLSATIQQYYSTRFRLILTGTPLQNNLAELWAMLNFVLPNIFKSAKTFDEWFNTPFAQDKMELTEEEQILVIRRLHKVLRPFLLRRLKKDVEKDLPDKTEKVIKCKFSALQARLYKQMVTHQKIAARGLSNMIMQLRKLCNHPFVFDEVENQMNPANVSNDLLWRTAGKFELLDRILPKYKATGHRVLMFFQMTAIMDIMEDFLRFRGLHYLRLDGTTKSEDRSELLRQFNQPDSPYFMFLLSTRALNLQTADTVIIYDSDIGQKNEVRILRLISSASVEEKILEGEQEEMDDDELNMILARNEEELAIFQKLDEERSRDPIYGTAPGCQGVPRLMTEDELPDIYLPVEEEVEMALG 5hzr A 2.33 BS04 KH2 A 4 F486 N572 L573 N574 R704 V728 L729 F29 N80 L81 N82 R208 V232 L233 G2QDW1 ANDEEAYLKLLDQAKDTRITHLLRQTDGFLKQLASSIDYYAVAHRIKEEVTEQASILVGGTLKEYQLKGLQWMLSLYNNNLNGILADEMGLGKTIQTISLITYLIEKKHQQGPYLVIVPLSTLTNWNLEFDKWAPSVAKVVYKGPPNARKMQQEKIRQGKFQVLLTTYEYIIKDRPLLSKIKWFHMIIDEGHRMSKLSATIQQYYSTRFRLILTGTPLQNNLAELWAMLNFVLPNIFKSAKTFDEWFNTPFAQDKMELTEEEQILVIRRLHKVLRPFLLRRLKKDVEKDLPDKTEKVIKCKFSALQARLYKQMVTHQKIAARGLSNMIMQLRKLCNHPFVFDEVENQMNPANVSNDLLWRTAGKFELLDRILPKYKATGHRVLMFFQMTAIMDIMEDFLRFRGLHYLRLDGTTKSEDRSELLRQFNQPDSPYFMFLLSTRALNLQTADTVIIYDSDIGQKNEVRILRLISSASVEEKILEGEQEEMDDDELNMILARNEEELAIFQKLDEERSRDPIYGTAPGCQGVPRLMTEDELPDIYLPVEEEVEMALG 5ic4 A 2.65 BS01 III I 1 R64 S65 H121 G122 Q161 C163 R30 S31 H87 G88 Q127 C129 3.4.22.56 27367566 NSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIE 5ic4 B 2.65 BS01 III I 1 Y204 S205 W206 R207 N208 S209 W214 S249 F250 Y20 S21 W22 R23 N24 S25 W30 S65 F66 3.4.22.56 P42574 27367566 HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 5ic4 C 2.65 BS01 III J 1 R64 H121 G122 Q161 C163 R30 H87 G88 Q127 C129 3.4.22.56 P42574 27367566 NSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIE 5ic4 D 2.65 BS01 III J 1 Y204 S205 W206 R207 N208 S209 W214 E248 S249 F250 Y19 S20 W21 R22 N23 S24 W29 E63 S64 F65 3.4.22.56 P42574 27367566 KIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 5ic4 E 2.65 BS01 III K 1 R64 H121 G122 Q161 C163 R30 H87 G88 Q127 C129 3.4.22.56 P42574 27367566 NSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIE 5ic4 F 2.65 BS01 III K 1 Y204 S205 W206 R207 N208 W214 E248 S249 F250 Y19 S20 W21 R22 N23 W29 E63 S64 F65 3.4.22.56 P42574 27367566 KIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 5ic4 G 2.65 BS01 III L 1 R64 H121 G122 Q161 C163 R29 H86 G87 Q126 C128 3.4.22.56 P42574 27367566 SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIET 5ic4 H 2.65 BS01 III L 1 Y204 S205 W206 R207 N208 S209 W214 S249 F250 Y20 S21 W22 R23 N24 S25 W30 S65 F66 3.4.22.56 P42574 27367566 HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 5ic6 A 2.70 BS01 III E 1 R87 H144 G145 Q184 C186 R31 H88 G89 Q128 C130 3.4.22.60 P55210 27367566 TYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQ 5ic6 B 2.70 BS01 III E 1 Y230 S231 W232 R233 S234 P235 S275 Q276 Y19 S20 W21 R22 S23 P24 S64 Q65 3.4.22.60 P55210 27367566 KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 5ic6 C 2.70 BS01 III F 1 R87 H144 G145 Q184 C186 R31 H88 G89 Q128 C130 3.4.22.60 P55210 27367566 TYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQ 5ic6 D 2.70 BS01 III F 1 Y230 S231 W232 R233 S234 W240 S275 Q276 Y19 S20 W21 R22 S23 W29 S64 Q65 3.4.22.60 P55210 27367566 KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 5iko A 2.50 BS01 PLP A 1 Y90 G135 W491 K568 Y648 R649 V650 G675 T676 G677 K680 Y70 G115 W459 K536 Y616 R617 V618 G643 T644 G645 K648 2.4.1.1 P11216 LGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDDFNVGDYIEAVLDRNLAENISRVLYPNDFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNI 5ikp A 3.40 BS01 PLP A 1 Y90 G135 K568 R569 K574 R649 A653 G675 T676 G677 K680 Y70 G115 K535 R536 K541 R616 A620 G642 T643 G644 K647 2.4.1.1 P11216 LGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDDFNVGDYIEAVLDRNLAENISRVLYPNDFEGKELRLKQEYFVVAATLQDIIRRFKSSKFTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNI 5ikp A 3.40 BS02 AMP A 1 Q71 Q72 Y75 Y196 R309 Q51 Q52 Y55 Y176 R283 2.4.1.1 P11216 LGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDDFNVGDYIEAVLDRNLAENISRVLYPNDFEGKELRLKQEYFVVAATLQDIIRRFKSSKFTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNI 5iql A 2.10 BS01 III B 1 H259 P260 S261 Y262 G281 W282 G283 E284 F285 L309 R311 Y313 H58 P59 S60 Y61 G80 W81 G82 E83 F84 L108 R110 Y112 Q9ULM3 27103431 SRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHR 5iwq A 2.00 BS01 PLP A 1 S103 S104 L105 Y142 V186 N191 D220 A222 Y223 S256 S258 K259 S100 S101 L102 Y139 V183 N188 D217 A219 Y220 S253 S255 K256 2.6.1.1 27355211 VSLQDFDAERIGLFHEDIKRKFDELKSKNLKLDLTRGKPSSEQLDFADELLALPGKGDFKAADGTDVRNYGGLDGIVDIRQIWADLLGVPVEQVLAGDASSLNIMFDVISWSYIFGNNDSVQPWSKEETVKWICPVPGYDRHFSITERFGFEMISVPMNEDGPDMDAVEELVKNPQVKGMWVVPVFSNPTGFTVTEDVAKRLSAMETAAPDFRVVWDNAYAVHTLTDEFPEVIDIVGLGEAAGNPNRFWAFTSTSKITLAGAGVSFFLTSAENRKWYTGHAGIRGIGPNKVNQLAHARYFGDAEGVRAVMRKHAASLAPKFNKVLEILDSRLAEYGVAQWTVPAGGYFISLDVVPGTASRVAELAKEAGIALTGAGSSYPLRQDPENKNLRLAPSLPPVEELEVAMDGVATCVLLAAAEHYANL 5iwq A 2.00 BS02 FLC B 1 Y73 I289 Y70 I286 2.6.1.1 27355211 VSLQDFDAERIGLFHEDIKRKFDELKSKNLKLDLTRGKPSSEQLDFADELLALPGKGDFKAADGTDVRNYGGLDGIVDIRQIWADLLGVPVEQVLAGDASSLNIMFDVISWSYIFGNNDSVQPWSKEETVKWICPVPGYDRHFSITERFGFEMISVPMNEDGPDMDAVEELVKNPQVKGMWVVPVFSNPTGFTVTEDVAKRLSAMETAAPDFRVVWDNAYAVHTLTDEFPEVIDIVGLGEAAGNPNRFWAFTSTSKITLAGAGVSFFLTSAENRKWYTGHAGIRGIGPNKVNQLAHARYFGDAEGVRAVMRKHAASLAPKFNKVLEILDSRLAEYGVAQWTVPAGGYFISLDVVPGTASRVAELAKEAGIALTGAGSSYPLRQDPENKNLRLAPSLPPVEELEVAMDGVATCVLLAAAEHYANL 5iwq B 2.00 BS01 PLP B 1 S103 S104 L105 Y142 V186 N191 D220 A222 Y223 S256 S258 K259 S100 S101 L102 Y139 V183 N188 D217 A219 Y220 S253 S255 K256 2.6.1.1 27355211 VSLQDFDAERIGLFHEDIKRKFDELKSKNLKLDLTRGKPSSEQLDFADELLALPGKGDFKAADGTDVRNYGGLDGIVDIRQIWADLLGVPVEQVLAGDASSLNIMFDVISWSYIFGNNDSVQPWSKEETVKWICPVPGYDRHFSITERFGFEMISVPMNEDGPDMDAVEELVKNPQVKGMWVVPVFSNPTGFTVTEDVAKRLSAMETAAPDFRVVWDNAYAVHTLTDEFPEVIDIVGLGEAAGNPNRFWAFTSTSKITLAGAGVSFFLTSAENRKWYTGHAGIRGIGPNKVNQLAHARYFGDAEGVRAVMRKHAASLAPKFNKVLEILDSRLAEYGVAQWTVPAGGYFISLDVVPGTASRVAELAKEAGIALTGAGSSYPLRQDPENKNLRLAPSLPPVEELEVAMDGVATCVLLAAAEHYANL 5iwq B 2.00 BS02 FLC B 1 R39 G40 K41 Y142 R144 K259 R394 R36 G37 K38 Y139 R141 K256 R391 2.6.1.1 27355211 VSLQDFDAERIGLFHEDIKRKFDELKSKNLKLDLTRGKPSSEQLDFADELLALPGKGDFKAADGTDVRNYGGLDGIVDIRQIWADLLGVPVEQVLAGDASSLNIMFDVISWSYIFGNNDSVQPWSKEETVKWICPVPGYDRHFSITERFGFEMISVPMNEDGPDMDAVEELVKNPQVKGMWVVPVFSNPTGFTVTEDVAKRLSAMETAAPDFRVVWDNAYAVHTLTDEFPEVIDIVGLGEAAGNPNRFWAFTSTSKITLAGAGVSFFLTSAENRKWYTGHAGIRGIGPNKVNQLAHARYFGDAEGVRAVMRKHAASLAPKFNKVLEILDSRLAEYGVAQWTVPAGGYFISLDVVPGTASRVAELAKEAGIALTGAGSSYPLRQDPENKNLRLAPSLPPVEELEVAMDGVATCVLLAAAEHYANL 5ixe A 1.75 BS01 14O A 1 G33 V37 W151 P152 G221 F222 P223 W433 A434 G33 V37 W151 P152 G221 F222 P223 W429 A430 3.2.1.23 P22498 27389009 MYSFPNSFRFGWSQAGFQSEMGTPGSEDPNTDGYKWVHDPENMAAGLVSGDLPENGPGYWGNYKTFHDNAQKMGLKIARLNVEWSRIFPNPLPRPQNFDESKQDVTEVEINENELKRLDEYANKDALNHYREIFKDLKSRGLYFILNMYHWPLPLWLHDPIRVRRGDFTGPSGWLSTRTVYEFARFSAYIAWKFDDLVDEYSTMNEPNVVGGLGYVGVKSGFPPGYLSFELSRRAMYNIIQAHARAYDGIKSVSKKPVGIIYANSSFQPLTDKDMEAVEMAENDNRWWFFDAIIRGEITKIVRDDLKGRLDWIGVNYYTRTVVKRTEKGYVSLGGYGHGCERNSVSLAGLPTSDFGWEFFPEGLYDVLTKYWNRYHLYMYVTENGIADDADYQRPYYLVSHVYQVHRAINSGADVRGYLHWSLADNYEWASGFSMRFGLLKVDYNTKRLYWRPSALVYREIATNGAITDEIEHLNSVPPVKPLRH 5ixe B 1.75 BS01 14O B 1 G33 V37 W151 P152 G221 F222 P223 W433 A434 G33 V37 W151 P152 G221 F222 P223 W432 A433 3.2.1.23 P22498 27389009 MYSFPNSFRFGWSQAGFQSEMGTPGSEDPNTDGYKWVHDPENMAAGLVSGDLPENGPGYWGNYKTFHDNAQKMGLKIARLNVEWSRIFPNPLPRPQNFDESKQDVTEVEINENELKRLDEYANKDALNHYREIFKDLKSRGLYFILNMYHWPLPLWLHDPIRVRRGDFTGPSGWLSTRTVYEFARFSAYIAWKFDDLVDEYSTMNEPNVVGGLGYVGVKSGFPPGYLSFELSRRAMYNIIQAHARAYDGIKSVSKKPVGIIYANSSFQPLTDKDMEAVEMAENDNRWWFFDAIIRGEITRGNKIVRDDLKGRLDWIGVNYYTRTVVKRTEKGYVSLGGYGHGCERNSVSLAGLPTSDFGWEFFPEGLYDVLTKYWNRYHLYMYVTENGIADDADYQRPYYLVSHVYQVHRAINSGADVRGYLHWSLADNYEWASGFSMRFGLLKVDYNTKRLYWRPSALVYREIATNGAITDEIEHLNSVPPVKPLRH 5izf A 2.10 BS01 6J9 E 1 L49 V57 A70 E121 Y122 V123 L173 T183 F327 L37 V45 A58 E109 Y110 V111 L161 T171 F315 2.7.11.11 P17612 27389935 ESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 5izf A 2.10 BS02 AZ1 E 1 G50 T51 G52 S53 F54 G55 K72 L74 G38 T39 G40 S41 F42 G43 K60 L62 2.7.11.11 P17612 27389935 ESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 5izf A 2.10 BS03 DAR E 1 G52 S53 F54 D166 K168 F187 T201 G40 S41 F42 D154 K156 F175 T189 2.7.11.11 P17612 27389935 ESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 5izf A 2.10 BS04 DAR E 2 P169 E170 T201 P202 E203 E230 P157 E158 T189 P190 E191 E218 2.7.11.11 P17612 27389935 ESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 5izj A 1.85 BS01 6J9 G 1 L49 V57 A70 M120 E121 Y122 V123 L173 T183 F327 L36 V44 A57 M107 E108 Y109 V110 L160 T170 F307 2.7.11.11 P17612 27389935 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFNFDDYEEEEIRVSINEKCGKEFSEF 5izj A 1.85 BS02 AZ1 G 1 G50 T51 G52 S53 F54 G55 V57 K72 L74 G37 T38 G39 S40 F41 G42 V44 K59 L61 2.7.11.11 P17612 27389935 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFNFDDYEEEEIRVSINEKCGKEFSEF 5izj A 1.85 BS03 DAR G 1 S53 F54 F187 S40 F41 F174 2.7.11.11 P17612 27389935 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFNFDDYEEEEIRVSINEKCGKEFSEF 5izj A 1.85 BS04 6J9 A 1 V15 F18 F100 L152 E155 K292 I303 Y306 V2 F5 F87 L139 E142 K279 I290 Y293 2.7.11.11 P17612 27389935 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFNFDDYEEEEIRVSINEKCGKEFSEF 5izj B 1.85 BS01 6J9 F 1 L49 V57 A70 V104 M120 E121 Y122 V123 L173 T183 L36 V44 A57 V91 M107 E108 Y109 V110 L160 T170 2.7.11.11 P17612 27389935 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGEEEEIRVSINEKCGKEFSEF 5izj B 1.85 BS02 AZ1 F 1 G50 G52 S53 F54 G55 V57 L74 G37 G39 S40 F41 G42 V44 L61 2.7.11.11 P17612 27389935 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGEEEEIRVSINEKCGKEFSEF 5izj B 1.85 BS03 DAR F 1 S53 F54 S40 F41 2.7.11.11 P17612 27389935 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGEEEEIRVSINEKCGKEFSEF 5izj B 1.85 BS04 DAR F 2 G52 S53 G39 S40 2.7.11.11 P17612 27389935 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGEEEEIRVSINEKCGKEFSEF 5izj B 1.85 BS05 6J9 B 1 F18 L152 I303 Y306 F5 L139 I290 Y293 2.7.11.11 P17612 27389935 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGEEEEIRVSINEKCGKEFSEF 5j40 A 2.17 BS01 ZN A 1 C303 C306 H314 H318 C38 C41 H49 H53 3.6.4.- P03072 27385654 TKQVSWKLVTQYALDTKCEDVFLLMGMYLNFQEAPAACAACAAADQPNHFNHHEKHYYNAQIFADSKNQKSICQQAVDTVAAKQRVDSLHMTREEMLVERFNFLLDKMDLIFGAHGNAVLEQYMAGVAWIHCLLPQMDTVIYEFLKCIVLNIPKKRYWLFKGPIDSGKTTLAAALLDLCGGKSLNVNMPLERLNFELGVGIDQFMVVFEDVKGTGAESRDLPSGHGISNLDCLRDYLDGSVKVNLERRTQVFPPGIVTMNEYSVPRTLQARFVRQIDFRPKAYLRKSLSCSEYLLEKRILQSGMTLLLLLIWFRPVADFAAAIHERIVQWKERLDLEISMYTFSTMKANVGMGAPILD 5j47 A 1.99 BS01 ZN A 1 C303 C306 H314 H318 C38 C41 H49 H53 3.6.4.- P03072 27385654 TKQVSWKLVTQYALDTKCEDVFLLMGMYLNFQEAPAACAACAAADQPNHFNHHEKHYYNAQIFADSKNQKSICQQAVDTVAAKQRVDSLHMTREEMLVERFNFLLDKMDLIFGAHGNAVLEQYMAGVAWIHCLLPQMDTVIYEFLKCIVLNIPKKRYWLFKGPIDSGKTTLAAALLDLCGGKSLNVNMPLERLNFELGVGIDQFMVVFEDVKGTGAESRDLPSGHGISNLDCLRDYLDGSVKVNLERNKRTQVFPPGIVTMNEYSVPRTLQARFVRQIDFRPKAYLRKSLSCSEYLLEKRILQSGMTLLLLLIWFRPVADFAAAIHERIVQWKERLDLEISMYTFSTMKANVGMGAPILD 5j47 A 1.99 BS02 6JJ A 1 W394 D430 S431 T435 P550 K551 L554 R555 L558 L565 W129 D165 S166 T170 P282 K283 L286 R287 L290 L297 3.6.4.- P03072 27385654 TKQVSWKLVTQYALDTKCEDVFLLMGMYLNFQEAPAACAACAAADQPNHFNHHEKHYYNAQIFADSKNQKSICQQAVDTVAAKQRVDSLHMTREEMLVERFNFLLDKMDLIFGAHGNAVLEQYMAGVAWIHCLLPQMDTVIYEFLKCIVLNIPKKRYWLFKGPIDSGKTTLAAALLDLCGGKSLNVNMPLERLNFELGVGIDQFMVVFEDVKGTGAESRDLPSGHGISNLDCLRDYLDGSVKVNLERNKRTQVFPPGIVTMNEYSVPRTLQARFVRQIDFRPKAYLRKSLSCSEYLLEKRILQSGMTLLLLLIWFRPVADFAAAIHERIVQWKERLDLEISMYTFSTMKANVGMGAPILD 5j4v A 2.94 BS01 ZN A 1 C303 C306 H314 H318 C38 C41 H49 H53 3.6.4.- P03072 27385654 TKQVSWKLVTQYALDTKCEDVFLLMGMYLNFQEAPAACAACAAADQPNHFNHHEKHYYNAQIFADSKNQKSICQQAVDTVAAKQRVDSLHMTREEMLVERFNFLLDKMDLIFGAHGNAVLEQYMAGVAWIHCLLPQMDTVIYEFLKCIVLNIPKKRYWLFKGPIDSGKTTLAAALLDLCGGKSLNVNMPLERLNFELGVGIDQFMVVFEDVKGTGAESRDLPSGHGISNLDCLRDYLDGSVKVNLERRTQVFPPGIVTMNEYSVPRTLQARFVRQIDFRPKAYLRKSLSCSEYLLEKRILQSGMTLLLLLIWFRPVADFAAAIHERIVQWKERLDLEISMYTFSTMKANVGMGAPILD 5j4v A 2.94 BS02 6JH A 1 W394 L398 D430 S431 G432 T435 P550 K551 L554 R555 L558 L565 W129 L133 D165 S166 G167 T170 P280 K281 L284 R285 L288 L295 3.6.4.- P03072 27385654 TKQVSWKLVTQYALDTKCEDVFLLMGMYLNFQEAPAACAACAAADQPNHFNHHEKHYYNAQIFADSKNQKSICQQAVDTVAAKQRVDSLHMTREEMLVERFNFLLDKMDLIFGAHGNAVLEQYMAGVAWIHCLLPQMDTVIYEFLKCIVLNIPKKRYWLFKGPIDSGKTTLAAALLDLCGGKSLNVNMPLERLNFELGVGIDQFMVVFEDVKGTGAESRDLPSGHGISNLDCLRDYLDGSVKVNLERRTQVFPPGIVTMNEYSVPRTLQARFVRQIDFRPKAYLRKSLSCSEYLLEKRILQSGMTLLLLLIWFRPVADFAAAIHERIVQWKERLDLEISMYTFSTMKANVGMGAPILD 5j4y A 2.59 BS01 ZN A 1 C303 C306 H314 H318 C38 C41 H49 H53 3.6.4.- P03072 27385654 TKQVSWKLVTQYALDTKCEDVFLLMGMYLNFQEAPAACAACAAADQPNHFNHHEKHYYNAQIFADSKNQKSICQQAVDTVAAKQRVDSLHMTREEMLVERFNFLLDKMDLIFGAHGNAVLEQYMAGVAWIHCLLPQMDTVIYEFLKCIVLNIPKKRYWLFKGPIDSGKTTLAAALLDLCGGKSLNVNMPLERLNFELGVGIDQFMVVFEDVKGTGAESRDLPSGHGISNLDCLRDYLDGSVKVNLERKHQNKRTQVFPPGIVTMNEYSVPRTLQARFVRQIDFRPKAYLRKSLSCSEYLLEKRILQSGMTLLLLLIWFRPVADFAAAIHERIVQWKERLDLEISMYTFSTMKANVGMGAPILD 5j4y A 2.59 BS02 6JG A 1 W394 L398 D430 S431 G432 T435 P550 K551 L554 R555 L558 L565 W129 L133 D165 S166 G167 T170 P285 K286 L289 R290 L293 L300 3.6.4.- P03072 27385654 TKQVSWKLVTQYALDTKCEDVFLLMGMYLNFQEAPAACAACAAADQPNHFNHHEKHYYNAQIFADSKNQKSICQQAVDTVAAKQRVDSLHMTREEMLVERFNFLLDKMDLIFGAHGNAVLEQYMAGVAWIHCLLPQMDTVIYEFLKCIVLNIPKKRYWLFKGPIDSGKTTLAAALLDLCGGKSLNVNMPLERLNFELGVGIDQFMVVFEDVKGTGAESRDLPSGHGISNLDCLRDYLDGSVKVNLERKHQNKRTQVFPPGIVTMNEYSVPRTLQARFVRQIDFRPKAYLRKSLSCSEYLLEKRILQSGMTLLLLLIWFRPVADFAAAIHERIVQWKERLDLEISMYTFSTMKANVGMGAPILD 5j5x A 2.60 BS01 6J9 A 1 V15 F18 F100 L152 E155 K292 I303 Y306 V7 F10 F92 L144 E147 K284 I295 Y298 2.7.11.11 P17612 27389935 GSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 5j8c A 2.17 BS01 ZN A 1 C210 C213 H226 C230 C36 C39 H52 C56 2.3.1.48 Q9H7Z6 GSKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVASILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPQKPLSDLGKLSYRSYWSWVLLEILRDFGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAP 5j8f A 2.60 BS01 ZN A 1 C210 C213 H226 C230 C35 C38 H51 C55 2.3.1.48 Q9H7Z6 SKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAP 5js1 A 2.50 BS01 NUC B 1 S220 A221 T222 F294 Y311 F312 H316 H336 T337 Y338 R351 T361 M364 I365 T368 L522 G524 T526 Y529 K533 Q545 C546 V547 Q548 N551 T559 N562 L563 K566 K570 K709 R714 H753 I756 Q757 T759 S760 R761 Y790 R792 C793 R795 V797 S798 Y804 R812 S188 A189 T190 F257 Y274 F275 H279 H299 T300 Y301 R314 T324 M327 I328 T331 L485 G487 T489 Y492 K496 Q508 C509 V510 Q511 N514 T522 N525 L526 K529 K533 K669 R674 H713 I716 Q717 T719 S720 R721 Y750 R752 C753 R755 V757 S758 Y764 R772 3.1.26.- Q9UKV8 27380263 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPRIFKVSIKWVSCVSLQALHDALSGRLVPFETIQALDVVMRHLPSMRYTPVGRSFFTASSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 5js1 A 2.50 BS02 MG A 1 D597 V598 D669 D560 V561 D629 3.1.26.- Q9UKV8 27380263 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPRIFKVSIKWVSCVSLQALHDALSGRLVPFETIQALDVVMRHLPSMRYTPVGRSFFTASSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 5js2 A 2.95 BS01 6OP B 1 G524 T526 Y529 K533 C546 Q548 K566 K570 Y815 G487 T489 Y492 K496 C509 Q511 K529 K533 Y774 3.1.26.- Q9UKV8 27380263 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPDRIFKVSIKWVSCVSLQALHDALSGRLVPFETIQALDVVMRHLPSMRYTPVGRSFFTASSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 5js2 A 2.95 BS02 F2T B 1 Q548 N551 T559 N562 L563 K566 Q511 N514 T522 N525 L526 K529 3.1.26.- Q9UKV8 27380263 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPDRIFKVSIKWVSCVSLQALHDALSGRLVPFETIQALDVVMRHLPSMRYTPVGRSFFTASSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 5js2 A 2.95 BS03 6NW B 1 N562 K566 R792 C793 N525 K529 R751 C752 3.1.26.- Q9UKV8 27380263 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPDRIFKVSIKWVSCVSLQALHDALSGRLVPFETIQALDVVMRHLPSMRYTPVGRSFFTASSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 5js2 A 2.95 BS04 UFT B 1 Y790 R792 C793 Y749 R751 C752 3.1.26.- Q9UKV8 27380263 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPDRIFKVSIKWVSCVSLQALHDALSGRLVPFETIQALDVVMRHLPSMRYTPVGRSFFTASSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 5js2 A 2.95 BS05 6OO B 1 H753 V797 S798 Y804 H712 V756 S757 Y763 3.1.26.- Q9UKV8 27380263 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPDRIFKVSIKWVSCVSLQALHDALSGRLVPFETIQALDVVMRHLPSMRYTPVGRSFFTASSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 5js2 A 2.95 BS06 MG A 1 D597 V598 D560 V561 3.1.26.- Q9UKV8 27380263 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPDRIFKVSIKWVSCVSLQALHDALSGRLVPFETIQALDVVMRHLPSMRYTPVGRSFFTASSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDDHQALAKAVQVHQDTLRTMYFA 5jwy A 3.20 BS01 46E A 1 Q50 V88 G89 K93 P160 G162 H163 M165 F166 S169 W170 L222 Q50 V88 G89 K93 P160 G162 H163 M165 F166 S169 W170 L222 3.1.3.27,3.1.3.81,3.1.3.4,3.6.1.27 P0A924 MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWVTETVTQPWGVITHLILFGWFLWCLRFRIKAAFVLFAILAAAILVGQGVKSWIKDKVQEPRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFPSGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLISWALVAVATWLAQRICGPLTPPAEENREIAQREQESLEHHH 5jxz A 1.88 BS01 MG A 1 E241 E376 E224 E359 5.4.4.2 P0AEJ3 27373320 TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASATRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jxz A 1.88 BS02 ISC A 1 E197 L212 A213 G214 S215 E241 H276 A303 L304 I346 R347 A360 G361 A362 G363 E376 K380 E180 L195 A196 G197 S198 E224 H259 A286 L287 I329 R330 A343 G344 A345 G346 E359 K363 5.4.4.2 P0AEJ3 27373320 TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASATRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jxz A 1.88 BS03 ISJ A 1 E197 L212 A213 G214 S215 E241 H276 A303 L304 I346 R347 A360 G361 A362 G363 E376 K380 E180 L195 A196 G197 S198 E224 H259 A286 L287 I329 R330 A343 G344 A345 G346 E359 K363 5.4.4.2 P0AEJ3 27373320 TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASATRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jxz B 1.88 BS01 MG B 1 E241 E376 E224 E355 5.4.4.2 P0AEJ3 27373320 ATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRSSELHVPSSPQLITTPTLWHLATPFEGKAQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jxz B 1.88 BS02 ISC B 1 E197 L212 G214 S215 E241 H276 A303 L304 I346 R347 A360 G361 A362 G363 E376 K380 E180 L195 G197 S198 E224 H257 A282 L283 I325 R326 A339 G340 A341 G342 E355 K359 5.4.4.2 P0AEJ3 27373320 ATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRSSELHVPSSPQLITTPTLWHLATPFEGKAQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jxz B 1.88 BS03 ISJ B 1 E197 L212 A213 G214 S215 E241 H276 A303 L304 I346 R347 A360 G361 A362 G363 E376 K380 E180 L195 A196 G197 S198 E224 H257 A282 L283 I325 R326 A339 G340 A341 G342 E355 K359 5.4.4.2 P0AEJ3 27373320 ATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRSSELHVPSSPQLITTPTLWHLATPFEGKAQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jy4 A 2.11 BS01 MG A 1 E241 E376 E227 E362 5.4.4.2 P0AEJ3 27373320 TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFG 5jy4 A 2.11 BS02 ISC A 1 E197 L212 A213 G214 S215 E241 H276 A303 L304 I346 R347 A360 G361 A362 G363 E376 K380 E183 L198 A199 G200 S201 E227 H262 A289 L290 I332 R333 A346 G347 A348 G349 E362 K366 5.4.4.2 P0AEJ3 27373320 TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFG 5jy4 B 2.11 BS01 MG B 1 K237 E241 E376 K220 E224 E359 5.4.4.2 P0AEJ3 27373320 TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH 5jy4 B 2.11 BS02 ISC B 1 E197 L212 G214 S215 E241 H276 A303 L304 I346 R347 A360 G361 A362 G363 E376 K380 E180 L195 G197 S198 E224 H259 A286 L287 I329 R330 A343 G344 A345 G346 E359 K363 5.4.4.2 P0AEJ3 27373320 TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH 5jy8 A 2.94 BS01 FE A 1 K237 E241 E376 K215 E219 E354 5.4.4.2 P0AEJ3 27373320 LAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASASLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jy8 A 2.94 BS02 FE A 2 E259 H261 E237 H239 5.4.4.2 P0AEJ3 27373320 LAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASASLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jy8 A 2.94 BS03 ISJ A 1 E197 L212 A213 G214 S215 E241 A303 L304 I346 F359 A360 G361 E376 K380 E175 L190 A191 G192 S193 E219 A281 L282 I324 F337 A338 G339 E354 K358 5.4.4.2 P0AEJ3 27373320 LAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASASLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jy8 B 2.94 BS01 FE B 1 K237 E241 E373 E376 K214 E218 E350 E353 5.4.4.2 P0AEJ3 27373320 LAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGEFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jy8 B 2.94 BS02 FE B 2 D40 E41 D25 E26 5.4.4.2 P0AEJ3 27373320 LAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGEFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jy8 B 2.94 BS03 ISJ B 1 E197 L212 A213 S215 E241 H276 A303 L304 I346 R347 A360 G361 G363 E376 K380 E175 L189 A190 S192 E218 H253 A280 L281 I323 R324 A337 G338 G340 E353 K357 5.4.4.2 P0AEJ3 27373320 LAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGEFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGL 5jy9 A 2.16 BS01 FE2 A 1 K280 E281 E284 G407 E417 E420 K247 E248 E251 G374 E384 E387 A1JTF3 27373320 EFLHWLPTISGVLRQFAEEECYVYERQPCWYLGKGCQARLHINADGTQATFIDDAGEQKWAVDSIADCARRFMAHPQVKGRRVYGQVGFNFAAHARGIAFNAGEWPLLTLTVPREELIFEKGNVTVYAAPLAVDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSFMFRQEGREALGFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCLPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRFDAALVLRSVFQDSQRCWIQAGAGIIAQSTPERELTETREKLASIAPYLMV 5jy9 B 2.16 BS01 FE2 B 1 E284 G407 E420 E274 G397 E410 A1JTF3 27373320 KISEFLHLPEEQWLPTISGVLRQFAEEECYVYERQPCWYLGKGCQARLHINADGTQATFIDDAGEQKWAVDSIADCARRFMAHPQVKGRRVYGQVGFNFAAHARGIAFNAGEWPLLTLTVPREELIFEKGNVTVYADSADGCRRLCEWVKNAPLAVDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSFMFRQEGREALGFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCLPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRFDAALVLRSVFQDSQRCWIQAGAGIIAQSTPERELTETREKLASIAPYLMV 5jys A 1.90 BS01 MG A 1 H208 L217 H250 H50 L59 H92 27344972 LSDFASSVLAEHNKKRALHKDTPALSWSDTLASYAQDYADNYDCSGTLTHSGGPYGENLALGYDGPAAVDAWYNEISNYDFSNPGFSSNTGHFTQVVWKSTTQVGCGIKTCGGAWGDYVICSYDPAGNYEGEYADNVEPLA 5jzd A 2.30 BS01 ISC A 1 E197 L212 G214 S215 E241 H276 A303 I346 R347 A360 G361 G363 E376 K380 E184 L199 G201 S202 E228 H263 A290 I333 R334 A347 G348 G350 E363 K367 5.4.4.2 P0AEJ2 27373320 ATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH 5jzd A 2.30 BS02 MG A 1 E241 G363 E376 E228 G350 E363 5.4.4.2 P0AEJ2 27373320 ATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH 5jzd B 2.30 BS01 ISC B 1 E197 L212 G214 S215 E241 H276 A303 I346 R347 A360 G361 A362 G363 E376 K380 E183 L198 G200 S201 E227 H262 A289 I332 R333 A346 G347 A348 G349 E362 K366 5.4.4.2 P0AEJ2 27373320 TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH 5jzd B 2.30 BS02 MG B 1 E241 E376 E227 E362 5.4.4.2 P0AEJ2 27373320 TLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH 5k16 A 2.60 BS01 ZN A 1 C186 C189 C233 C236 C148 C151 C190 C193 3.4.19.12 O75317 27373336 SALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSKNSESGYILFYQSRD 5k16 B 2.60 BS01 ZN B 1 C186 C189 C233 C236 C149 C152 C196 C199 3.4.19.12 O75317 27373336 NASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLKNSESGYILFYQSRD 5k1a A 2.30 BS01 ZN A 1 C186 C189 C233 C236 C95 C98 C138 C141 3.4.19.12 O75317 27373336 LVNFGNTCYCNSVLQALYFCRPFREKVLAYSLLTCLADLFHSIATPPKKFITRLAHEFLNYLLNTIADILQEERKQEPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKVFPLELRLFDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYNSESGYILFYQSR 5k1a C 2.30 BS01 ZN C 1 C186 C189 C233 C236 C97 C100 C141 C144 3.4.19.12 O75317 27373336 LVNFGNTCYCNSVLQALYFCRPFREKVLAYSLLTCLADLFHSIATIPPKKFITRLRKAHEFLNYLLNTIADILQEERKQPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLVFPLELRLFDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAISESGYILFYQSR 5k1a E 2.30 BS01 ZN E 1 C186 C189 C233 C236 C81 C84 C124 C127 3.4.19.12 O75317 27373336 FGNTCYCNSVLQALYFCRPFREKVLAYSLLTCLADLFHSIPPKKFHEFLNYLLNTIADILQEEPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLVFPLELRLFDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYSGYILFYQSRD 5k1a G 2.30 BS01 ZN G 1 C186 C189 C233 C236 C84 C87 C127 C130 3.4.19.12 O75317 27373336 LVNFGNTCYCNSVLQALYFCRPFREKVLAYSLLTCLADLFHSIAHEFLNYLLNTIADILQEERKQEPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKVFPLELRLFDRMYDLVAVVVHCSGPNRGHYIAIVKSHDFWLLFDDIVEKIDAQAIEEFSESGYILFYQSR 5k1b A 3.30 BS01 ZN A 1 C186 C189 C233 C236 C113 C116 C156 C159 3.4.19.12 O75317 27373336 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQESLLTCLADLFHSIATQVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEEPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFSYRVVFPLELRLFPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHWLLFDDDIVEKIDAQAIEEFYKNSESGYILFYQSRD 5k1c A 3.00 BS01 ZN A 1 C186 C189 C233 C236 C118 C121 C165 C168 3.4.19.12 O75317 27373336 HYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYSLLTCLADLFHSIATQVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD 5k1j B 1.69 BS01 RE B 1 T75 W79 E89 T66 W70 E80 P02766 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 5k1n A 1.81 BS01 RE A 1 H88 E89 H90 H79 E80 H81 P02766 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN 5k1n A 1.81 BS02 RE B 1 F95 T96 F86 T87 P02766 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN 5k1n B 1.81 BS01 RE A 1 V93 V94 V84 V85 P02766 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 5k1n B 1.81 BS02 RE B 1 H88 Y114 H79 Y105 P02766 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 5k1n B 1.81 BS03 RE B 2 I107 Y116 I98 Y107 P02766 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 5k3q A 1.80 BS01 ZN A 1 C97 H100 C116 C119 C4 H7 C23 C26 6.3.2.-,6.3.2.- Q0PF16 VDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEEV 5k3q A 1.80 BS02 ZN A 2 C108 D111 H125 H128 C15 D18 H32 H35 6.3.2.-,6.3.2.- Q0PF16 VDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEEV 5k3q B 1.80 BS01 ZN B 1 C97 H100 C116 C119 C5 H8 C24 C27 6.3.2.-,6.3.2.- Q0PF16 GVDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEE 5k3q B 1.80 BS02 ZN B 2 C108 D111 H125 H128 C16 D19 H33 H36 6.3.2.-,6.3.2.- Q0PF16 GVDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEE 5k3q C 1.80 BS01 ZN C 1 C108 D111 H125 H128 C15 D18 H32 H35 6.3.2.-,6.3.2.- Q0PF16 VDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEE 5k3q C 1.80 BS02 ZN C 2 C97 H100 C116 C119 C4 H7 C23 C26 6.3.2.-,6.3.2.- Q0PF16 VDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEE 5k3q D 1.80 BS01 ZN D 1 C108 D111 H125 H128 C15 D18 H32 H35 6.3.2.-,6.3.2.- Q0PF16 VDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLME 5k3q D 1.80 BS02 ZN D 2 C97 H100 C116 C119 C4 H7 C23 C26 6.3.2.-,6.3.2.- Q0PF16 VDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLME 5k49 A 1.72 BS01 CU6 A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 S88 T90 W92 W108 L110 S112 D128 N12 L14 S16 Y32 S34 V36 G37 N38 W68 S77 T79 W81 W97 L99 S101 D117 P22629 27385206 RDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVK 5k67 A 1.70 BS01 SI4 A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 S88 T90 W92 W108 L110 C112 T114 K121 L124 D128 N12 L14 S16 Y32 S34 V36 G37 N38 W68 S77 T79 W81 W97 L99 C101 T103 K110 L113 D117 P22629 27385206 RDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTCGTTEANAWKSTLVGHDTFTKVK 5k68 A 1.40 BS01 SI9 A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 S88 T90 W92 W108 L110 C112 T114 K121 L124 D128 N12 L14 S16 Y32 S34 V36 G37 N38 W68 S77 T79 W81 W97 L99 C101 T103 K110 L113 D117 P22629 27385206 RDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTCGTTEANAWKSTLVGHDTFTKVK 5kew A 2.10 BS01 6SB A 1 S170 S181 F183 S6 S17 F19 Q87GI4 27377244 DYPSLSFQQDYVYIFSSDFQLSEELGVALINALSAKEIVPERLYVMLNDKTISFSFISKNKKSKNRVLSTEKKLNYKHISEYIVNEIEY 5kew B 2.10 BS01 6SB B 1 Y39 Y48 H50 I69 E71 Y81 P121 S123 I124 F150 Y151 Y10 Y19 H21 I40 E42 Y52 P92 S94 I95 F121 Y122 Q87GI3 27377244 DPVHFYETSYKYQAADSTYMHDVAINVSIKGNHFTSDIIIRELVKSENKNYYNVIGHGDIIQKNTHQYYLNFDNIDVYTGTNKANMKPYKEPTSISSLINKSNNIRVVYLSEEYVVVEFFFYDGQIITLHRY 5kew D 2.10 BS01 6SB D 1 Y39 I69 Y81 V83 Y118 F150 Y151 Y9 I39 Y51 V53 Y88 F114 Y115 Q87GI3 27377244 PVHFYETSYKYQAADSTYMHDVAINVSIKGNHFTSDIIIRELVKSENKNYYNVIGHGDIIQKNTHQYYLNFDNIDVYTGTNKANMKPYSSLINKSNNIRVVYLSEEYVVVEFFFYDGQIITLHRY 5kew F 2.10 BS01 6SB F 1 Y39 Y48 H50 I69 E71 Y81 P121 S123 I124 F150 Y151 Y9 Y18 H20 I39 E41 Y47 P87 S89 I90 F116 Y117 Q87GI3 27377244 PVHFYETSYKYQAADSTYMHDVAINVSIKGNHFTSDIIIRELVKNYYNVIGHGDIIQKNTHQYYLNFDNIDVYTGTNKANMKPYKEPTSISSLINKSNNIRVVYLSEEYVVVEFFFYDGQIITLHRY 5kh4 A 3.20 BS01 FPP A 1 M27 D28 G29 N30 G31 H45 M49 A71 R79 I87 L90 F94 F143 M14 D15 G16 N17 G18 H32 M36 A58 R66 I74 L77 F81 F130 2.5.1.- Q97SR4 27379833 EVPTQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNR 5kh4 B 3.20 BS01 FPP B 1 M27 G29 N30 G31 R32 H45 M49 L52 A71 R79 I87 L90 P91 F143 L145 M13 G15 N16 G17 R18 H31 M35 L38 A57 R65 I73 L76 P77 F129 L131 2.5.1.- Q97SR4 27379833 VPTQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNR 5kh5 B 2.63 BS01 6TC B 1 M27 N30 H45 G48 A71 I87 L90 P91 F94 L118 L126 F143 L145 W227 M11 N14 H29 G32 A55 I66 L69 P70 F73 L97 L105 F122 L124 W206 2.5.1.- Q97SR4 27379833 TQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNRRH 5ki6 A 2.15 BS01 NUC B 1 A221 R277 F294 L296 Y311 F312 H316 H336 T337 Y338 L356 D358 T361 M364 I365 T368 K525 Y529 K533 T544 Q545 C546 V547 Q548 N551 Q558 T559 N562 L563 K566 K570 K709 R714 H753 I756 Q757 T759 S760 R761 Y790 R792 C793 V797 S798 Y804 R812 Y815 A188 R238 F255 L257 Y272 F273 H277 H297 T298 Y299 L316 D318 T321 M324 I325 T328 K485 Y489 K493 T504 Q505 C506 V507 Q508 N511 Q518 T519 N522 L523 K526 K530 K669 R674 H713 I716 Q717 T719 S720 R721 Y750 R752 C753 V757 S758 Y764 R772 Y775 3.1.26.- Q9UKV8 27387838 AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLRIFKVSIKWVSCVSLQALHDALSGRLVPFETIQALDVVMRHLPSMRYTPVGRSFFTASNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLHQALAKAVQVHQDTLRTMYFA 5kjr G 2.98 BS01 III N 1 V255 A281 S365 G366 G367 D368 E370 I371 S375 F376 F382 M426 W427 G472 G473 N474 V131 A157 S216 G217 G218 D219 E221 I222 S226 F227 F233 M266 W267 G312 G313 N314 A0A0M3KKW9 27384653 VWKDADTTLFCASDAKAHETEVHNVAATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQWLQPCVKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQLFNNTCIKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE 5kp2 B 2.00 BS01 COA B 1 T31 W35 R39 R152 F214 G216 F220 A253 N254 R256 I257 T30 W34 R38 R151 F213 G215 F219 A252 N253 R255 I256 2.3.1.180 Q9KLJ3 TQCYAEITGWGKCLPPATLSNHDLSTFLDTSDEWIQSRTGIEQRRISHVNTSDLATVAAQHAIACAGVSVEEIDLIIVATCSPDSLIPNIASRVQQNLGIPSAAAFDLNAAATGFLYGLETATRLMQASHYRHALVIGAERLSFYLDWTKRDTAVLFGDGAGAVVLSKTEQKVGLQDAQIGCDAQGRDILAVPKFGTAMDRFDADNGYWAFDFVGKEIFKRAVRGMGAAAQQVLARSGLSTEEIDVVIPHQANIRIIQTLCDLAGIAQDKAFVNIHRYGNTSAATVPIALCEALEQGKIKPHDDLLVAAFGAGLTWGAGHIRWGERITPLGKSDAQLPSCDHTALDLLSKAIEHCKRH 5kp2 B 2.00 BS02 OCA B 1 A112 A113 L143 Y146 F158 H251 N281 G312 A313 A111 A112 L142 Y145 F157 H250 N280 G311 A312 2.3.1.180 Q9KLJ3 TQCYAEITGWGKCLPPATLSNHDLSTFLDTSDEWIQSRTGIEQRRISHVNTSDLATVAAQHAIACAGVSVEEIDLIIVATCSPDSLIPNIASRVQQNLGIPSAAAFDLNAAATGFLYGLETATRLMQASHYRHALVIGAERLSFYLDWTKRDTAVLFGDGAGAVVLSKTEQKVGLQDAQIGCDAQGRDILAVPKFGTAMDRFDADNGYWAFDFVGKEIFKRAVRGMGAAAQQVLARSGLSTEEIDVVIPHQANIRIIQTLCDLAGIAQDKAFVNIHRYGNTSAATVPIALCEALEQGKIKPHDDLLVAAFGAGLTWGAGHIRWGERITPLGKSDAQLPSCDHTALDLLSKAIEHCKRH 5kre A 2.00 BS01 6WG A 1 G29 S30 Y66 R80 I83 S124 M125 F150 L181 V182 H211 G22 S23 Y59 R73 I76 S117 M118 F143 L174 V175 H204 3.1.2.- Q5VWZ2 27391855 VLQRCIVSPAGRHSASLIFLHGSGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRILIGGFSMGGCMAMHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNVYHELSKTELDILKLWILTKLPG 5ks7 A 2.90 BS01 2BA B 1 P259 V260 V280 D281 T282 Y342 I355 T357 R358 A359 P13 V14 V34 D35 T36 Y96 I109 T111 R112 A113 3.6.3.32 Q9KHT9 27378384 DVTQVAQIMNTNPVSITADKSLQAAITVMKEKRVDTLLVVDEGNVLKGFIDVEQIDLNRRTATSVMDIIEKNVFYVYEDTLLRDTVQRILKRGYKYIPVVDKDKRLVGIVTRASLVDIVYDSI 5ks7 B 2.90 BS01 2BA B 1 V260 V280 D281 T282 L284 Y342 I355 T357 R358 A359 V13 V33 D34 T35 L37 Y95 I108 T110 R111 A112 3.6.3.32 Q9KHT9 27378384 VTQVAQIMNTNPVSITADKSLQAAITVMKEKRVDTLLVVDEGNVLKGFIDVEQIDLNRRTATSVMDIIEKNVFYVYEDTLLRDTVQRILKRGYKYIPVVDKDKRLVGIVTRASLVDIVYDSI 5l3y A 1.70 BS01 CU6 A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 A86 S88 T90 W92 W108 L110 C112 G113 L124 D128 N12 L14 S16 Y32 S34 V36 G37 N38 W68 A75 S77 T79 W81 W97 L99 C101 G102 L113 D117 P22629 27385206 RDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTCGTTEANAWKSTLVGHDTFTKVK 5l7d A 3.20 BS01 CLR A 1 D95 K105 L108 W109 G111 L112 N114 I156 R161 V210 A492 D38 K48 L51 W52 G54 L55 N57 I99 R104 V153 A527 Q99835 PPPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGFVWFVVLTYAWHTSFKALQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLSKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCRLT 5l7i A 3.30 BS01 VIS A 1 L221 W281 D384 S387 Y394 R400 Q477 W480 F484 E518 N521 L522 M525 L165 W225 D319 S322 Y329 R335 Q500 W503 F507 E531 N534 L535 M538 Q99835 PPPPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGFVWFVVLTYAWHTSFLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLSKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCR 5l7i B 3.30 BS01 VIS B 1 L221 W281 D384 S387 Y394 R400 D473 Q477 W480 P513 E518 N521 L522 M525 L164 W224 D327 S330 Y337 R343 D503 Q507 W510 P533 E538 N541 L542 M545 Q99835 PPPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGFVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLSKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCRL 5l7i B 3.30 BS02 MPG B 1 P306 L312 I316 L376 A377 P249 L255 I259 L319 A320 Q99835 PPPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGFVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLSKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCRL 5l7i B 3.30 BS03 MPG B 2 W256 Y269 H361 W365 W199 Y212 H304 W308 Q99835 PPPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGFVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLSKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCRL 5l8j A 1.68 BS01 ADP A 1 L139 G140 G142 K143 V147 A160 K162 E211 Y212 A213 L263 L14 G15 G17 K18 V22 A35 K37 E86 Y87 A88 L138 2.7.11.1 O14965 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5l8k A 1.79 BS01 ADP A 1 L139 G140 G142 K143 V147 A160 K162 L194 E211 Y212 A213 L263 L14 G15 G17 K18 V22 A35 K37 L69 E86 Y87 A88 L138 2.7.11.1 O14965 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 5l8l A 1.67 BS01 ADP A 1 L139 G140 K141 G142 K143 V147 A160 K162 L194 E211 A213 L263 L14 G15 K16 G17 K18 V22 A35 K37 L69 E86 A88 L138 2.7.11.1 O14965 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 5la6 A 2.10 BS01 GTP A 1 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 V177 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 V177 E183 N206 Y224 N228 I231 P81947 27395016 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVD 5la6 A 2.10 BS02 CA A 1 D39 T41 G44 G45 E55 D39 T41 G44 G45 E55 P81947 27395016 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVD 5la6 B 2.10 BS01 GDP B 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 P173 V177 D179 E183 N206 Y224 N228 G9 Q10 C11 Q14 S137 G140 G141 T142 G143 P170 V174 D176 E180 N203 Y221 N225 Q6B856 27395016 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5la6 C 2.10 BS01 GTP C 1 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 I231 P81947 27395016 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5la6 C 2.10 BS02 CA C 1 D39 T41 G44 G45 E55 D39 T41 G44 G45 E55 P81947 27395016 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5la6 C 2.10 BS03 X3H C 1 C4 L167 I238 S241 L242 F255 C316 L317 L318 C376 L378 C4 L167 I238 S241 L242 F247 C308 L309 L310 C368 L370 P81947 27395016 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5la6 D 2.10 BS01 GDP D 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 V177 S178 E183 N206 Y224 N228 G9 Q10 C11 Q14 S137 G140 G141 T142 G143 V174 S175 E180 N203 Y221 N225 Q6B856 27395016 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5la6 F 2.10 BS01 ACP F 1 K74 I148 K150 K156 Q183 K184 Y185 L186 K198 R202 R222 L240 T241 N242 D318 M320 I330 E331 N333 K74 I128 K130 K136 Q163 K164 Y165 L166 K178 R182 R202 L220 T221 N222 D298 M300 I310 E311 N313 E1BQ43 27395016 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTNLDEREVFLAAYNRRREGREGNVWIAKSSAGAKGEGILISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKLHH 5lcj A 1.78 BS01 L01 A 1 I31 G32 E33 V39 A52 Q105 D106 L107 M108 E109 K114 S153 L156 C166 I21 G22 E23 V29 A42 Q95 D96 L97 M98 E99 K104 S143 L146 C156 2.7.11.24 P28482 27385078 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDELDDLPKEKLKELIFEETARFQPG 5lck A 1.89 BS01 6TT A 1 I31 G32 E33 V39 A52 Q105 D106 L107 M108 E109 D111 K114 S153 L156 C166 I21 G22 E23 V29 A42 Q95 D96 L97 M98 E99 D101 K104 S143 L146 C156 2.7.11.24 P28482 27385078 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG