2n8y A BS01 CA A 1 D759 D761 S763 T765 E770 D20 D22 S24 T26 E31 P12814 27272015 GSSISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCIARMAPYTGPDSVPGALDYMSFSTALYGESDL 2ncz A BS01 III B 1 Y12 K15 R16 L18 S19 I22 L30 V34 I37 P49 D50 E51 I52 E53 I54 D55 F56 E57 Y12 K15 R16 L18 S19 I22 L30 V34 I37 P49 D50 E51 I52 E53 I54 D55 F56 E57 O60885 27291650 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA 2nd0 A BS01 III B 1 Y12 K15 S19 G27 L30 G31 V34 Q38 P49 D50 E51 I52 E53 I54 D55 F56 E57 Y12 K15 S19 G27 L30 G31 V34 Q38 P49 D50 E51 I52 E53 I54 D55 F56 E57 O60885 27291650 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA 2nd1 A BS01 III B 1 Y12 K15 R16 S19 I22 N23 K24 L25 P26 L30 D50 E51 I52 E53 I54 D55 F56 E57 K80 Q82 Y12 K15 R16 S19 I22 N23 K24 L25 P26 L30 D50 E51 I52 E53 I54 D55 F56 E57 K80 Q82 O60885 27291650 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA 4ydp A 1.40 BS01 GLU A 1 Q66 K70 Q66 K70 O75112 MAYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKS 4ydp A 1.40 BS02 GLU A 2 G14 R16 T33 G14 R16 T33 O75112 MAYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKS 4ydp A 1.40 BS03 LEU A 1 P12 W13 G14 F15 L17 Q66 I69 K70 P12 W13 G14 F15 L17 Q66 I69 K70 O75112 MAYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKS 4yew C 2.68 BS01 NUC D 1 Q43 V45 G46 T49 G82 K83 Q43 V45 G46 T49 G63 K64 P0ACF2 MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHRNVPAFVSGKALKDAVK 4yex C 3.20 BS01 NUC B 1 S17 K18 T19 S17 K18 T19 P0ACF2 MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHANVPAFVSGKALKDAVK 4yex C 3.20 BS02 NUC D 1 K3 T4 K3 T4 P0ACF2 MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHANVPAFVSGKALKDAVK 4yey C 3.35 BS02 NUC D 1 K3 T4 E26 K4 T5 E27 P0ACF2 AMNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHAANVPAFVSGKALKDAVK 4yf0 A 2.79 BS01 NUC C 1 Q43 V45 G46 G82 K83 Q43 V45 G46 G68 K69 P0ACF2 MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKKGDALQLVGFGTFKVNHRAERAANVPAFVSGKALKDAVK 4yf0 B 2.79 BS01 NUC D 1 Q43 V45 G46 G82 K83 Q44 V46 G47 G81 K82 P0ACF2 HMNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKKGDALQLVGFGTFKVNHRAERTGPQTGKEIKIAAANVPAFVSGKALKDAVK 4ym9 A 1.80 BS01 4E4 A 1 H57 T96 V99 C191 Q192 G193 S195 T213 S214 F215 V216 H45 T85 V88 C184 Q185 G186 S188 T206 S207 F208 V209 3.4.21.36 P00772 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN 4z33 A 2.45 BS01 III C 1 H208 V209 G210 F211 I212 F213 K214 T219 D251 S252 L258 H99 V100 G101 F102 I103 F104 K105 T110 D142 S143 L149 O00560 SGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAFIF 4z33 A 2.45 BS02 IP2 A 1 N215 K250 D251 N106 K141 D142 O00560 SGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAFIF 4z33 B 2.45 BS01 III D 1 H208 V209 G210 F211 I212 F213 L258 H98 V99 G100 F101 I102 F103 L148 O00560 GIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAFIF 4z9g A 3.18 BS01 1Q5 A 1 F203 M206 G210 L280 N283 F284 L287 T316 L319 L320 L323 G324 F93 M96 G100 L329 N332 F333 L336 T365 L368 L369 L372 G373 3.2.1.17 P34998 KSKVHYHVAAIINYLGHCISLVALLVAFVLFLRARSIRCLRNIIHANLIAAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLSVAKSELDKAIGRNSNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRSALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVIATFRTGTWDAYLTDRLRAWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWAGKRPGVYTDYIYQGPMALVLLINFIFLFNIVRILMTKLRASTTSETIQARKAVKATLVLLPLLGITYMLAFVNPGEDEVSRVVFIYFNAFLESFQGFFVSVFACFLNSEVRS 4z9g B 3.18 BS01 1Q5 B 1 F203 M206 G210 V279 L280 N283 L287 T316 L320 L323 F91 M94 G98 V326 L327 N330 L334 T363 L367 L370 3.2.1.17 P34998 KVHYHVAAIINYLGHCISLVALLVAFVLFLRARSIRCLRNIIHANLIAAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLSVAKSELDKAIGRNSNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRSALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVIATFRTGTWDAYLTDRLRAWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWAGKRPGVYTDYIYQGPMALVLLINFIFLFNIVRILMTKLRASTTSETIQARKAVKATLVLLPLLGITYMLAFVDEVSRVVFIYFNAFLESFQGFFVSVFACFLNSEVRS 4z9g C 3.18 BS01 1Q5 C 1 F203 M206 G210 N283 L287 T316 L323 G324 F89 M92 G96 N322 L326 T355 L362 G363 3.2.1.17 P34998 SKVHYHVAAIINYLGHCISLVALLVAFVLFLRARSIRCLRNIIHANLIAAFILRNATWFVVQLPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLSVAKSELDKAIGRNSNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRSALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVIATFRTGTWDAYLTDRLRAWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWAYTDYIYQGPMALVLLINFIFLFNIVRILMTKLRASTTSETIQARKAVKATLVLLPLLGITYMLAFEVSRVVFIYFNAFLESFQGFFVSVFACFLNSEV 4zda A 2.80 BS01 MN A 1 D352 D551 D555 D347 D546 D550 1.1.1.42 A0QSZ3 PTIIYTLTDEAPLLATYAFLPVVRKFAEAAGIDVKTSDISVAARILAEFGDHLTEEQRVPDNLGELGALTQDPSANIIKLPNISASVPQLLAAIKELQGKGYNVPDYPANPKTDDEKKIKDRYAKILGSAVNPVLREGNSDRRAPKAVKEYARKHPHSMGEWSQASRTHVATMKTGDFYHGEKSMTLDRDRRVKMVLKTKSGEEIVLKPEVKLDAGDIIDSMYMSKKALIAFYEEQIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHEKLFDELGVNVNNGLSDLYDKIEALPASQREEIIEDLHKCHEHRPELAMVDSAKGISNFHSPSDVIVDASMPAMIRLGGKMYGADGRTKDTKAVNPESTFSRMYQEMINFCKTHGQFDPTTMGTVPNVGLMAQKAEEYGSHDKTFEIPEDGVADIVDIDTGEVLLTQNVEEGDIWRMPIVKDAPIRDWVKLAVTRARLSGMPVVFWLDTERPHEVELRKKVKEYLKDHDTEGLKIQIMPQVWAMRYTLERVVRGKDTIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVHQLVEENHLRWDSLGEFLALGASLEDMGNKTGNEKAKVLAKALDTATGKLLEENKSPSRRTGELDNRGSQFYLSLFWAQALAEQTEDAELAERFKPLAKALAEQEEAIVSELNSVQGKTVDIGGYYYPDPEKTSEVMRPSKTFNTTL 4zda A 2.80 BS02 ICT A 1 S134 N137 R141 R147 K257 M260 D352 Y422 R550 D551 A585 S129 N132 R136 R142 K252 M255 D347 Y417 R545 D546 A580 1.1.1.42 A0QSZ3 PTIIYTLTDEAPLLATYAFLPVVRKFAEAAGIDVKTSDISVAARILAEFGDHLTEEQRVPDNLGELGALTQDPSANIIKLPNISASVPQLLAAIKELQGKGYNVPDYPANPKTDDEKKIKDRYAKILGSAVNPVLREGNSDRRAPKAVKEYARKHPHSMGEWSQASRTHVATMKTGDFYHGEKSMTLDRDRRVKMVLKTKSGEEIVLKPEVKLDAGDIIDSMYMSKKALIAFYEEQIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHEKLFDELGVNVNNGLSDLYDKIEALPASQREEIIEDLHKCHEHRPELAMVDSAKGISNFHSPSDVIVDASMPAMIRLGGKMYGADGRTKDTKAVNPESTFSRMYQEMINFCKTHGQFDPTTMGTVPNVGLMAQKAEEYGSHDKTFEIPEDGVADIVDIDTGEVLLTQNVEEGDIWRMPIVKDAPIRDWVKLAVTRARLSGMPVVFWLDTERPHEVELRKKVKEYLKDHDTEGLKIQIMPQVWAMRYTLERVVRGKDTIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVHQLVEENHLRWDSLGEFLALGASLEDMGNKTGNEKAKVLAKALDTATGKLLEENKSPSRRTGELDNRGSQFYLSLFWAQALAEQTEDAELAERFKPLAKALAEQEEAIVSELNSVQGKTVDIGGYYYPDPEKTSEVMRPSKTFNTTL 4zef A 1.40 BS01 GLN A 1 D267 F270 F308 A325 G326 M327 T328 R333 K373 T376 E377 D417 Y443 D23 F26 F64 A81 G82 M83 T84 R89 K129 T132 E133 D173 Y199 Q837S0 ENLYFQGMKKITPKKEKYVIASDSTFAPFEFQNAQGDYVGIDVDLVKRAAELQGFTVEFKFIGFSSAVQAVESGQADGMVAGMTITDDRKKAFDFSVPYFDSGIQIAVKKGNDKIKSYDDLKGKKVGVKIGTESADFLEKNKKKYDYSIKYLDTTDALYSALEIGEVDAMMDDYPVIGYGVAQNQPLATPIPREKGGSYGFAVKKGQNPELLEMFNEGLKEMKRTGEYDKIIGTYVKDG 4zen A 1.93 BS01 BGP A 1 Q23 H124 W125 N169 E170 Y301 W352 E378 W425 S432 W433 N435 K439 Y441 Q19 H120 W121 N165 E166 Y297 W348 E374 W421 S428 W429 N431 K435 Y437 3.2.1.85 W8QF82 HLKPFPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPGRTFKGTNGDVAVDHYHRYQEDVALMAEMGLKAYRFSVSWSRVFPDGNGAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWDVPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNEQNIFISFGYRLGLHPPGVKDMKRMYEANHIANLANAKVIQSFRHYVPDGKIGPSFAYSPMYPYDSRPENVLAFENAEEFQNHWWMDVYAWGMYPQAAWNYLESQGLEPTVAPGDWELLQAAKPDFMGVNYYQTTTVEHNPPDGVGEGVMNTTGKKGTSTSSGIPGLFKTVRNPHVDTTNWDWAIDPVGLRIGLRRIANRYQLPILITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEIQRAITDGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQRVIETNGAEL 4zen B 1.93 BS01 BGP B 1 Q23 H124 N169 E170 Y301 E378 W425 S432 W433 N435 K439 Y441 Q19 H120 N165 E166 Y297 E374 W421 S428 W429 N431 K435 Y437 3.2.1.85 W8QF82 HLKPFPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPGRTFKGTNGDVAVDHYHRYQEDVALMAEMGLKAYRFSVSWSRVFPDGNGAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWDVPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNEQNIFISFGYRLGLHPPGVKDMKRMYEANHIANLANAKVIQSFRHYVPDGKIGPSFAYSPMYPYDSRPENVLAFENAEEFQNHWWMDVYAWGMYPQAAWNYLESQGLEPTVAPGDWELLQAAKPDFMGVNYYQTTTVEHNPPDGVGEGVMNTTGKKGTSTSSGIPGLFKTVRNPHVDTTNWDWAIDPVGLRIGLRRIANRYQLPILITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEIQRAITDGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQRVIETNGAEL 4zep A 2.21 BS01 BG6 A 1 Q23 H124 E170 Y301 W352 E378 W425 S432 W433 N435 K439 Y441 Q19 H120 E166 Y297 W348 E374 W421 S428 W429 N431 K435 Y437 3.2.1.85 W8QF82 HLKPFPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPGRTFKGTNGDVAVDHYHRYQEDVALMAEMGLKAYRFSVSWSRVFPDGNGAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWDVPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNEQNIFISFGYRLGLHPPGVKDMKRMYEANHIANLANAKVIQSFRHYVPDGKIGPSFAYSPMYPYDSRPENVLAFENAEEFQNHWWMDVYAWGMYPQAAWNYLESQGLEPTVAPGDWELLQAAKPDFMGVNYYQTTTVEHNPPDGVGEGVMNTTGKKGTSTSSGIPGLFKTVRNPHVDTTNWDWAIDPVGLRIGLRRIANRYQLPILITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEIQRAITDGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQRVIETNGAEL 4zep B 2.21 BS01 BG6 B 1 Q23 E170 W352 E378 W425 S432 W433 N435 K439 Y441 Q19 E166 W348 E374 W421 S428 W429 N431 K435 Y437 3.2.1.85 W8QF82 HLKPFPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPGRTFKGTNGDVAVDHYHRYQEDVALMAEMGLKAYRFSVSWSRVFPDGNGAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWDVPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNEQNIFISFGYRLGLHPPGVKDMKRMYEANHIANLANAKVIQSFRHYVPDGKIGPSFAYSPMYPYDSRPENVLAFENAEEFQNHWWMDVYAWGMYPQAAWNYLESQGLEPTVAPGDWELLQAAKPDFMGVNYYQTTTVEHNPPDGVGEGVMNTTGKKGTSTSSGIPGLFKTVRNPHVDTTNWDWAIDPVGLRIGLRRIANRYQLPILITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEIQRAITDGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQRVIETNGAEL 4zfm A 1.40 BS01 BG6 A 1 Q23 H124 Q170 I173 W352 E378 W425 S432 W433 N435 K439 Y441 Q19 H120 Q166 I169 W335 E361 W408 S415 W416 N418 K422 Y424 3.2.1.85 W8QF82 HLKPFPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPGRTFKGTNGDVAVDHYHRYQEDVALMAEMGLKAYRFSVSWSRVFPDGNGAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWDVPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNQQNIFISFGYRLGLHPPGVKDMKRMYEANHIANLANAKVIQSFRHYVPDGKIGPSFAYSPMYPYDSRPENVLAFENAEEFQNHWWMDVYAWGMYPQAAWNYLESQGLEPTVAPGDWELLQAAKPDFMGVNYYQTTTVEHNPPDGVGTSSGIPGLFKTVRNPHVDTTNWDWAIDPVGLRIGLRRIANRYQLPILITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEIQRAITDGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQRVIETNGAEL 4zfm C 1.40 BS01 0WK C 1 Q23 H124 Q170 E378 W425 S432 W433 Y441 Q19 H120 Q166 E361 W408 S415 W416 Y424 3.2.1.85 W8QF82 HLKPFPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPGRTFKGTNGDVAVDHYHRYQEDVALMAEMGLKAYRFSVSWSRVFPDGNGAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWDVPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNQQNIFISFGYRLGLHPPGVKDMKRMYEANHIANLANAKVIQSFRHYVPDGKIGPSFAYSPMYPYDSRPENVLAFENAEEFQNHWWMDVYAWGMYPQAAWNYLESQGLEPTVAPGDWELLQAAKPDFMGVNYYQTTTVEHNPPDGVGTSSGIPGLFKTVRNPHVDTTNWDWAIDPVGLRIGLRRIANRYQLPILITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEIQRAITDGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQRVIETNGAEL 4zfm C 1.40 BS02 BGC C 1 Q170 I173 F177 A226 Y301 Q166 I169 F173 A222 Y297 3.2.1.85 W8QF82 HLKPFPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPGRTFKGTNGDVAVDHYHRYQEDVALMAEMGLKAYRFSVSWSRVFPDGNGAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWDVPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNQQNIFISFGYRLGLHPPGVKDMKRMYEANHIANLANAKVIQSFRHYVPDGKIGPSFAYSPMYPYDSRPENVLAFENAEEFQNHWWMDVYAWGMYPQAAWNYLESQGLEPTVAPGDWELLQAAKPDFMGVNYYQTTTVEHNPPDGVGTSSGIPGLFKTVRNPHVDTTNWDWAIDPVGLRIGLRRIANRYQLPILITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEIQRAITDGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQRVIETNGAEL 4zfm D 1.40 BS02 BGC D 1 Q170 Y301 Q166 Y297 3.2.1.85 W8QF82 HLKPFPPEFLWGAASAAYQVEGAWNEDGKGLSVWDVFAKQPGRTFKGTNGDVAVDHYHRYQEDVALMAEMGLKAYRFSVSWSRVFPDGNGAVNEKGLDFYDRLIEELRNHGIEPIVTLYHWDVPQALMDAYGAWESRRIIDDFDRYAVTLFQRFGDRVKYWVTLNQQNIFISFGYRLGLHPPGVKDMKRMYEANHIANLANAKVIQSFRHYVPDGKIGPSFAYSPMYPYDSRPENVLAFENAEEFQNHWWMDVYAWGMYPQAAWNYLESQGLEPTVAPGDWELLQAAKPDFMGVNYYQTTTVEHNPPDGVGTSSGIPGLFKTVRNPHVDTTNWDWAIDPVGLRIGLRRIANRYQLPILITENGLGEFDTLEPGDIVNDDYRIDYLRRHVQEIQRAITDGVDVLGYCAWSFTDLLSWLNGYQKRYGFVYVNRDDESEKDLRRIKKKSFYWYQRVIETNGAEL 4zg8 A 1.39 BS01 CA A 1 A215 D218 E219 D255 A208 D211 E212 D248 3.2.1.4 F2Z7L1 AQYNYREVLQKSILFYAAQRSGQLPGNNPIDWRDDSALDDQGNGGEDLTGGWYDAGDHVKFGLPMAWTATTLIWGMIDLANGYGGDRNDAMQSVRWALDYFMKCHVSDNELYGQVGDGHADHAYWGRPEEMTMDRPAWSLTPSAPGSDLAGETAAALAAGSILFSDSDASYANQLLDHARTIYDFAYNNRGIYSESIPNAADFYRSSAYEDELCWGALWLYRATGEQDYMDKANEFLPQGRPWAFSWDSKEAGSLVLLTSFGNSNARAQLEDFLQSWFPGGDIHYTPLGLAWRDTWGSLRYSANSAFIALLAAEEGVLTSQARTFARAQLDYMLGSTGRSFVVGFGTNPPLRPHHRAASCPDMPASCGWDQASDPAPNPQVLDGALVGGPDDQDNYNDDRQDYISNEVACDYNAGFQGALAGILQL 4zh5 A 1.35 BS02 BGC A 1 D398 D399 N402 D390 D391 N394 3.2.1.4 F2Z7L1 QYNYREVLQKSILFYAAQRSGQLPGNNPIDWRDDSALDDQGNGGEDLTGGWYDAGDHVKFGLPMAWTATTLIWGMIDLANGYGGDRNDAMQSVRWALDYFMKCHVSDNELYGQVGDGHADHAYWGRPEEMTMDRPAWSLTPSAPGSDLAGETAAALAAGSILFSDSDASYANQLLDHARTIYDFAYNNRGIYSESIPNAADFYRSSAYEDELCWGALWLYRATGEQDYMDKANEFLPQGRPWAFSWDSKEAGSLVLLTSFGNSNARAQLEDFLQSWFPGGDIHYTPLGLAWRDTWGSLRYSANSAFIALLAAEEGVLTSQARTFARAQLDYMLGSTGRSFVVGFGTNPPLRPHHRAASCPDMPASCGWDQASDPAPNPQVLDGALVGGPDDQDNYNDDRQDYISNEVACDYNAGFQGALAGILQL 4zi1 A 2.10 BS01 III B 1 I310 K314 L324 Q327 V328 E332 L490 E493 I49 K53 L63 Q66 V67 E71 L218 E221 Q92731 ALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRG 4zi1 A 2.10 BS02 KB0 A 1 L298 T299 L301 A302 E305 W335 M336 L339 L343 R346 F356 I373 I376 G472 H475 L476 L491 L37 T38 L40 A41 E44 W74 M75 L78 L82 R85 F95 I112 I115 G200 H203 L204 L219 Q92731 ALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRG 4zk6 A 1.90 BS01 SF4 A 1 Y23 C83 M85 C170 C256 Y23 C83 M85 C170 C256 2.5.1.72 O57767 27224840 MDLVEEILRLKEERNAIILAHNYQLPEVQDIADFIGDSLELARRATRVDADVIVFAGVDFMAETAKILNPDKVVLIPSREATCAMANMLKVEHILEAKRKYPNAPVVLYVNSTAEAKAYADVTVTSANAVEVVKKLDSDVVIFGPDKNLAHYVAKMTGKKIIPVPSKGHCYVHQKFTLDDVERAKKLHPNAKLMIHPECIPEVQEKADIIASTGGMIKRACEWDEWVVFTEREMVYRLRKLYPQKKFYPAREDAFCIGMKAITLKNIYESLKDMKYKVEVPEEIARKARKAIERMLEMS 4zk6 A 1.90 BS02 NTM A 1 H21 Y23 D37 S38 M61 Y109 N111 H173 H196 E198 H21 Y23 D37 S38 M61 Y109 N111 H173 H196 E198 2.5.1.72 O57767 27224840 MDLVEEILRLKEERNAIILAHNYQLPEVQDIADFIGDSLELARRATRVDADVIVFAGVDFMAETAKILNPDKVVLIPSREATCAMANMLKVEHILEAKRKYPNAPVVLYVNSTAEAKAYADVTVTSANAVEVVKKLDSDVVIFGPDKNLAHYVAKMTGKKIIPVPSKGHCYVHQKFTLDDVERAKKLHPNAKLMIHPECIPEVQEKADIIASTGGMIKRACEWDEWVVFTEREMVYRLRKLYPQKKFYPAREDAFCIGMKAITLKNIYESLKDMKYKVEVPEEIARKARKAIERMLEMS 4zk6 B 1.90 BS01 SF4 B 1 Y23 C83 A84 C170 C256 Y22 C82 A83 C169 C255 2.5.1.72 O57767 27224840 DLVEEILRLKEERNAIILAHNYQLPEVQDIADFIGDSLELARRATRVDADVIVFAGVDFMAETAKILNPDKVVLIPSREATCAMANMLKVEHILEAKRKYPNAPVVLYVNSTAEAKAYADVTVTSANAVEVVKKLDSDVVIFGPDKNLAHYVAKMTGKKIIPVPSKGHCYVHQKFTLDDVERAKKLHPNAKLMIHPECIPEVQEKADIIASTGGMIKRACEWDEWVVFTEREMVYRLRKLYPQKKFYPAREDAFCIGMKAITLKNIYESLKDMKYKVEVPEEIARKARKAIERMLEMS 4znx A 2.10 BS01 III E 1 Y91 Y93 R96 T97 D100 E116 G117 D118 W119 Y132 P134 N136 Y137 Y8 Y10 R13 T14 D17 E33 G34 D35 W36 Y49 P51 N53 Y54 2.7.10.2 P06241 VTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPV 4znx A 2.10 BS02 III F 1 T85 F87 I111 S114 S115 D118 W120 S135 N136 V138 A139 P140 T2 F4 I28 S31 S32 D35 W37 S52 N53 V55 A56 P57 2.7.10.2 P06241 VTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPV 4znx B 2.10 BS02 III G 1 D118 W120 S135 N136 V138 A139 P140 D33 W35 S50 N51 V53 A54 P55 2.7.10.2 P06241 LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPV 4znx C 2.10 BS02 III H 1 F87 S114 D118 W120 S135 N136 V138 A139 P140 F2 S29 D33 W35 S50 N51 V53 A54 P55 2.7.10.2 P06241 LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPV 4znx D 2.10 BS01 III E 1 F87 L90 Y91 S114 S115 D118 W120 S135 N136 V138 A139 P140 F3 L6 Y7 S30 S31 D34 W36 S51 N52 V54 A55 P56 2.7.10.2 P06241 TLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPV 4zny A 2.40 BS01 III B 1 D34 T58 Y63 Y68 N69 I70 P71 T92 M95 P139 V141 F142 S143 D31 T55 Y60 Y65 N66 I67 P68 T89 M92 P136 V138 F139 S140 Q99816 SESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRP 4zqf A 2.20 BS01 MG A 1 D153 E155 E234 D149 E151 E224 1.1.1.267 LQSLAILGATGSIGDSTLAIIRQHPNRYRIHALTGFSRVDKLLALAMEFHPVKICTSPDNYAQLSQKVTDAGLDTIILSGDEGLIEIASDEAVDTVVAAIVGAAGLSSTLAAAGAGKRILLANKESLVMAGDLVIKTAKKHGATILPIDSEHNAIYQCLPAAIQADNTAIHHTSYGIKKLWLTASGGSFLDKSIKQMQNASVKEAVMGQKISIDSATMMNKGLELIEACHLFDLKEHQIQVVIHPNSVVHSLVEYVDGSFLAQLGTPDMKTPIAHALAYPERIKSGVMPLDLYQLGSLKFLAPDLDKFACLKLARYAARLGTGACIALNTANEIAVEAFLAEKICLTDIAVIVKACLDDKTIAQDYSQDFGDEVLGLERILTMDKKVRKIATAKIKLLKQGD 4zqf A 2.20 BS02 FOM A 1 D153 S154 E155 A188 S189 S225 N230 K231 E234 D149 S150 E151 A184 S185 S215 N220 K221 E224 1.1.1.267 LQSLAILGATGSIGDSTLAIIRQHPNRYRIHALTGFSRVDKLLALAMEFHPVKICTSPDNYAQLSQKVTDAGLDTIILSGDEGLIEIASDEAVDTVVAAIVGAAGLSSTLAAAGAGKRILLANKESLVMAGDLVIKTAKKHGATILPIDSEHNAIYQCLPAAIQADNTAIHHTSYGIKKLWLTASGGSFLDKSIKQMQNASVKEAVMGQKISIDSATMMNKGLELIEACHLFDLKEHQIQVVIHPNSVVHSLVEYVDGSFLAQLGTPDMKTPIAHALAYPERIKSGVMPLDLYQLGSLKFLAPDLDKFACLKLARYAARLGTGACIALNTANEIAVEAFLAEKICLTDIAVIVKACLDDKTIAQDYSQDFGDEVLGLERILTMDKKVRKIATAKIKLLKQGD 4zqg A 2.50 BS01 NAD A 1 G12 T14 G15 S16 I17 G39 F40 A103 I104 V105 A108 A126 N127 E129 D153 M217 G218 I221 M279 G8 T10 G11 S12 I13 G35 F36 A99 I100 V101 A104 A122 N123 E125 D149 M213 G214 I217 M275 1.1.1.267 LQSLAILGATGSIGDSTLAIIRQHPNRYRIHALTGFSRVDKLLALAMEFHPVKICTSPDNYAQLSQKVTDAGLDTIILSGDEGLIEIASDEAVDTVVAAIVGAAGLSSTLAAAGAGKRILLANKESLVMAGDLVIKTAKKHGATILPIDSEHNAIYQCLPAAIQADNTAIHHTSYGIKKLWLTASGGSFLDKSIKQMQNASVKEAVNHPNWSMGQKISIDSATMMNKGLELIEACHLFDLKEHQIQVVIHPNSVVHSLVEYVDGSFLAQLGTPDMKTPIAHALAYPERIKSGVMPLDLYQLGSLKFLAPDLDKFACLKLARYAARLGTGACIALNTANEIAVEAFLAEKICLTDIAVIVKACLDDKTIAQDYSQDFGDEVLGLERILTMDKKVRKIATAKIKLLKQGD 4zqg A 2.50 BS03 FOM A 1 D153 S154 E155 A188 S189 W215 M217 I221 S225 N230 K231 E234 D149 S150 E151 A184 S185 W211 M213 I217 S221 N226 K227 E230 1.1.1.267 LQSLAILGATGSIGDSTLAIIRQHPNRYRIHALTGFSRVDKLLALAMEFHPVKICTSPDNYAQLSQKVTDAGLDTIILSGDEGLIEIASDEAVDTVVAAIVGAAGLSSTLAAAGAGKRILLANKESLVMAGDLVIKTAKKHGATILPIDSEHNAIYQCLPAAIQADNTAIHHTSYGIKKLWLTASGGSFLDKSIKQMQNASVKEAVNHPNWSMGQKISIDSATMMNKGLELIEACHLFDLKEHQIQVVIHPNSVVHSLVEYVDGSFLAQLGTPDMKTPIAHALAYPERIKSGVMPLDLYQLGSLKFLAPDLDKFACLKLARYAARLGTGACIALNTANEIAVEAFLAEKICLTDIAVIVKACLDDKTIAQDYSQDFGDEVLGLERILTMDKKVRKIATAKIKLLKQGD 4zqh A 2.40 BS01 NDP A 1 G12 T14 G15 S16 I17 F40 S41 R42 A103 I104 V105 A108 A126 N127 K128 E129 D153 M217 G218 I221 M279 G8 T10 G11 S12 I13 F36 S37 R38 A99 I100 V101 A104 A122 N123 K124 E125 D149 M213 G214 I217 M275 1.1.1.267 LQSLAILGATGSIGDSTLAIIRQHPNRYRIHALTGFSRVDKLLALAMEFHPVKICTSPDNYAQLSQKVTDAGLDTIILSGDEGLIEIASDEAVDTVVAAIVGAAGLSSTLAAAGAGKRILLANKESLVMAGDLVIKTAKKHGATILPIDSEHNAIYQCLPAAIQADNTAIHHTSYGIKKLWLTASGGSFLDKSIKQMQNASVKEAVNHPNWSMGQKISIDSATMMNKGLELIEACHLFDLKEHQIQVVIHPNSVVHSLVEYVDGSFLAQLGTPDMKTPIAHALAYPERIKSGVMPLDLYQLGSLKFLAPDLDKFACLKLARYAARLGTGACIALNTANEIAVEAFLAEKICLTDIAVIVKACLDDKTIAQDYSQDFGDEVLGLERILTMDKKVRKIATAKIKLLKQGD 4zqh A 2.40 BS02 MG A 1 K128 D153 E155 E234 K124 D149 E151 E230 1.1.1.267 LQSLAILGATGSIGDSTLAIIRQHPNRYRIHALTGFSRVDKLLALAMEFHPVKICTSPDNYAQLSQKVTDAGLDTIILSGDEGLIEIASDEAVDTVVAAIVGAAGLSSTLAAAGAGKRILLANKESLVMAGDLVIKTAKKHGATILPIDSEHNAIYQCLPAAIQADNTAIHHTSYGIKKLWLTASGGSFLDKSIKQMQNASVKEAVNHPNWSMGQKISIDSATMMNKGLELIEACHLFDLKEHQIQVVIHPNSVVHSLVEYVDGSFLAQLGTPDMKTPIAHALAYPERIKSGVMPLDLYQLGSLKFLAPDLDKFACLKLARYAARLGTGACIALNTANEIAVEAFLAEKICLTDIAVIVKACLDDKTIAQDYSQDFGDEVLGLERILTMDKKVRKIATAKIKLLKQGD 4zqh A 2.40 BS03 FOM A 1 K128 D153 S154 E155 A188 S189 H212 W215 M217 S225 N230 K231 E234 M279 K124 D149 S150 E151 A184 S185 H208 W211 M213 S221 N226 K227 E230 M275 1.1.1.267 LQSLAILGATGSIGDSTLAIIRQHPNRYRIHALTGFSRVDKLLALAMEFHPVKICTSPDNYAQLSQKVTDAGLDTIILSGDEGLIEIASDEAVDTVVAAIVGAAGLSSTLAAAGAGKRILLANKESLVMAGDLVIKTAKKHGATILPIDSEHNAIYQCLPAAIQADNTAIHHTSYGIKKLWLTASGGSFLDKSIKQMQNASVKEAVNHPNWSMGQKISIDSATMMNKGLELIEACHLFDLKEHQIQVVIHPNSVVHSLVEYVDGSFLAQLGTPDMKTPIAHALAYPERIKSGVMPLDLYQLGSLKFLAPDLDKFACLKLARYAARLGTGACIALNTANEIAVEAFLAEKICLTDIAVIVKACLDDKTIAQDYSQDFGDEVLGLERILTMDKKVRKIATAKIKLLKQGD 4zs9 A 1.37 BS01 RAF A 1 F57 K58 E60 N109 D111 N165 S167 W216 Q219 A220 Y291 D326 F392 D394 H395 F9 K10 E12 N54 D56 N110 S112 W161 Q164 A165 Y236 D271 F337 D339 H340 QVTLDFFQFKAEAADWFKQAAQEFEKENPDIRININNLRTRFVKDRVPDVITFNGDYSFGTFAASGVFHDFTDDPLVSELNEGMVNIAKNLVQTSDPAKKRLYGLPFAGNASGYIYNKDLFRKVGLDPDNPPQTWDEFIAMLKKFRDAGINPVQATLADAWTTQAPLASLAGTLVPESEYAALKSGDTTFKQIWTEPIEKEIELFKYADSEKGVTYQQGTQNFAKGTAAIIPLGTYAIPQITMVNKDIDLGFAQMPATNDASKQILTAGDDVILTMGANSRHKEQSMRFIRFLMSKKQLENYADAQSAITPLKETYFGNKALEPVRPFFESNRVADFCDHYIPSSINIGGYLQSAIMSGNVNQFIDSMQNEWNKVQA 4zza A 2.02 BS01 RAF A 1 F57 K58 E60 N109 G110 D111 W216 Q219 A220 Y291 D326 F392 D394 H395 F8 K9 E11 N44 G45 D46 W151 Q154 A155 Y226 D261 F327 D329 H330 VTLDFFQFKAEAADWFKQAAQEFEKENPDIRININRVPDVITFNGDYSFGTFAASGVFHDFTDDPLVSELNEGMVNIAKNLVQTSDPAKKRLYGLPFAGNASGYIYNKDLFRKVGLDPDNPPQTWDEFIAMLKKFRDAGINPVQATLADAWTTQAPLASLAGTLVPESEYAALKSGDTTFKQIWTEPIEKEIELFKYADSEKGVTYQQGTQNFAKGTAAIIPLGTYAIPQITMVNKDIDLGFAQMPATNDASKQILTAGDDVILTMGANSRHKEQSMRFIRFLMSKKQLENYADAQSAITPLKETYFGNKALEPVRPFFESNRVADFCDHYIPSSINIGGYLQSAIMSGNVNQFIDSMQNEWNK 4zze A 1.76 BS01 GLC A 1 N109 A220 Y291 F392 D394 H395 N54 A165 Y236 F337 D339 H340 QVTLDFFQFKAEAADWFKQAAQEFEKENPDIRININDLRTRFVKDRVPDVITFNGDYSFGTFAASGVFHDFTDDPLVSELNEGMVNIAKNLVQTSDPAKKRLYGLPFAGNASGYIYNKDLFRKVGLDPDNPPQTWDEFIAMLKKFRDAGINPVQATLADAWTTQAPLASLAGTLVPESEYAALKSGDTTFKQIWTEPIEKEIELFKYADSEKGVTYQQGTQNFAKGTAAIIPLGTYAIPQITMVNKDIDLGFAQMPATNDASKQILTAGDDVILTMGANSRHKEQSMRFIRFLMSKKQLENYADAQSAITPLKETYFGNKALEPVRPFFESNRVADFCDHYIPSSINIGGYLQSAIMSGNVNQFIDSMQNEWNKVQA 4zze A 1.76 BS02 GLC A 2 K58 E60 N109 W216 Y291 D326 K10 E12 N54 W161 Y236 D271 QVTLDFFQFKAEAADWFKQAAQEFEKENPDIRININDLRTRFVKDRVPDVITFNGDYSFGTFAASGVFHDFTDDPLVSELNEGMVNIAKNLVQTSDPAKKRLYGLPFAGNASGYIYNKDLFRKVGLDPDNPPQTWDEFIAMLKKFRDAGINPVQATLADAWTTQAPLASLAGTLVPESEYAALKSGDTTFKQIWTEPIEKEIELFKYADSEKGVTYQQGTQNFAKGTAAIIPLGTYAIPQITMVNKDIDLGFAQMPATNDASKQILTAGDDVILTMGANSRHKEQSMRFIRFLMSKKQLENYADAQSAITPLKETYFGNKALEPVRPFFESNRVADFCDHYIPSSINIGGYLQSAIMSGNVNQFIDSMQNEWNKVQA 4zze A 1.76 BS03 MG A 1 D315 S317 D260 S262 QVTLDFFQFKAEAADWFKQAAQEFEKENPDIRININDLRTRFVKDRVPDVITFNGDYSFGTFAASGVFHDFTDDPLVSELNEGMVNIAKNLVQTSDPAKKRLYGLPFAGNASGYIYNKDLFRKVGLDPDNPPQTWDEFIAMLKKFRDAGINPVQATLADAWTTQAPLASLAGTLVPESEYAALKSGDTTFKQIWTEPIEKEIELFKYADSEKGVTYQQGTQNFAKGTAAIIPLGTYAIPQITMVNKDIDLGFAQMPATNDASKQILTAGDDVILTMGANSRHKEQSMRFIRFLMSKKQLENYADAQSAITPLKETYFGNKALEPVRPFFESNRVADFCDHYIPSSINIGGYLQSAIMSGNVNQFIDSMQNEWNKVQA 4zze A 1.76 BS04 MG A 2 N300 D302 N245 D247 QVTLDFFQFKAEAADWFKQAAQEFEKENPDIRININDLRTRFVKDRVPDVITFNGDYSFGTFAASGVFHDFTDDPLVSELNEGMVNIAKNLVQTSDPAKKRLYGLPFAGNASGYIYNKDLFRKVGLDPDNPPQTWDEFIAMLKKFRDAGINPVQATLADAWTTQAPLASLAGTLVPESEYAALKSGDTTFKQIWTEPIEKEIELFKYADSEKGVTYQQGTQNFAKGTAAIIPLGTYAIPQITMVNKDIDLGFAQMPATNDASKQILTAGDDVILTMGANSRHKEQSMRFIRFLMSKKQLENYADAQSAITPLKETYFGNKALEPVRPFFESNRVADFCDHYIPSSINIGGYLQSAIMSGNVNQFIDSMQNEWNKVQA 4zze B 1.76 BS01 GLC B 1 N109 Q219 A220 Y291 F392 D394 H395 N53 Q163 A164 Y235 F336 D338 H339 QVTLDFFQFKAEAADWFKQAAQEFEKENPDIRININLRTRFVKDRVPDVITFNGDYSFGTFAASGVFHDFTDDPLVSELNEGMVNIAKNLVQTSDPAKKRLYGLPFAGNASGYIYNKDLFRKVGLDPDNPPQTWDEFIAMLKKFRDAGINPVQATLADAWTTQAPLASLAGTLVPESEYAALKSGDTTFKQIWTEPIEKEIELFKYADSEKGVTYQQGTQNFAKGTAAIIPLGTYAIPQITMVNKDIDLGFAQMPATNDASKQILTAGDDVILTMGANSRHKEQSMRFIRFLMSKKQLENYADAQSAITPLKETYFGNKALEPVRPFFESNRVADFCDHYIPSSINIGGYLQSAIMSGNVNQFIDSMQNEWNKVQA 5a3l A 1.66 BS01 CA A 1 D136 D137 N202 L204 E205 R206 D104 D105 N170 L172 E173 R174 TAYGCDITTNAVDGFDATIYQYNANDLRLIRDPTFMSTGYLGRNVLNKISGVTVPGFNIWNPSSRTATVYGVKNVNYYNMVLELKGYFKADVSGDYKLTLSHIDDSSMLFFGKETAFKCCDAGSIPLNEAPTDYSLFTIKPSNQVNSEVISATQYLEAGKYYPVRIVFVNALERARFDFKLTIPSGAVLDDFQNYIYQFGDLDENSCHE 5a3l A 1.66 BS02 NAG A 1 W92 D136 D137 K172 S174 N175 L204 E205 R206 W60 D104 D105 K140 S142 N143 L172 E173 R174 TAYGCDITTNAVDGFDATIYQYNANDLRLIRDPTFMSTGYLGRNVLNKISGVTVPGFNIWNPSSRTATVYGVKNVNYYNMVLELKGYFKADVSGDYKLTLSHIDDSSMLFFGKETAFKCCDAGSIPLNEAPTDYSLFTIKPSNQVNSEVISATQYLEAGKYYPVRIVFVNALERARFDFKLTIPSGAVLDDFQNYIYQFGDLDENSCHE 5a3l B 1.66 BS02 NAG B 1 W92 D136 D137 K172 S174 L204 E205 R206 W60 D104 D105 K140 S142 L172 E173 R174 TAYGCDITTNAVDGFDATIYQYNANDLRLIRDPTFMSTGYLGRNVLNKISGVTVPGFNIWNPSSRTATVYGVKNVNYYNMVLELKGYFKADVSGDYKLTLSHIDDSSMLFFGKETAFKCCDAGSIPLNEAPTDYSLFTIKPSNQVNSEVISATQYLEAGKYYPVRIVFVNALERARFDFKLTIPSGAVLDDFQNYIYQFGDLDENSCHE 5a3x A 2.26 BS01 QIV A 1 F170 A186 K188 V222 F238 E239 L241 L294 V306 D307 F37 A53 K55 V89 F105 E106 L108 L161 V173 D174 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTEYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKK 5a3x B 2.26 BS01 QIV B 1 F170 A186 K188 E239 L241 L294 D307 F38 A54 K56 E107 L109 L162 D175 2.7.12.1 Q13627 RKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKK 5a3x D 2.26 BS01 QIV D 1 F170 A186 K188 F238 E239 L241 L294 D307 F37 A53 K55 F105 E106 L108 L161 D174 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKYKPPGTRKLHNILGVETGGPGGTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 5a4e A 2.68 BS01 7QQ A 1 F170 F238 E239 L241 L294 V306 D307 F37 F105 E106 L108 L161 V173 D174 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTEYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 5a4e B 2.68 BS01 7QQ B 1 I165 F170 V173 A186 K188 F238 E239 L241 L294 V306 D307 I33 F38 V41 A54 K56 F100 E101 L103 L156 V168 D169 2.7.12.1 Q13627 RKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 5a4e C 2.68 BS01 7QQ C 1 I165 F170 A186 K188 F238 L241 L294 V306 I32 F37 A53 K55 F103 L106 L159 V171 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVAPKARKILRMLDYDPKTRIQPYYA 5a4l A 2.73 BS01 ZC3 A 1 A186 K188 F238 L294 D307 A53 K55 F105 L161 D174 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTEYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 5a4l B 2.73 BS01 ZC3 B 1 F170 A186 F238 E239 L241 V306 D307 F38 A54 F106 E107 L109 V174 D175 2.7.12.1 Q13627 RKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 5a4l C 2.73 BS01 ZC3 C 1 I165 F170 V173 A186 K188 F238 L241 L294 V306 D307 I31 F36 V39 A52 K54 F104 L107 L160 V172 D173 2.7.12.1 Q13627 VYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFWNLKKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 5a4l D 2.73 BS01 ZC3 D 1 A186 K188 F238 E239 L241 L294 D307 A53 K55 F105 E106 L108 L161 D174 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKYKPPGTRKLHNILGVETGGPGGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 5a4q A 2.37 BS01 Y3L A 1 I165 A186 F238 E239 M240 L241 L294 I32 A53 F105 E106 M107 L108 L161 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTEYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 5a4q C 2.37 BS01 Y3L C 1 I165 A186 F238 E239 L241 L294 I31 A52 F104 E105 L107 L160 2.7.12.1 Q13627 VYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFWNLKKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 5a4q D 2.37 BS01 Y3L D 1 I165 A186 F238 E239 M240 L241 S242 L294 I32 A53 F105 E106 M107 L108 S109 L161 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKYKPPGTRKLHNILGVETGGPGGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 5a4t A 2.15 BS01 AJG A 1 I165 V173 A186 E239 L241 L294 I32 V40 A53 E106 L108 L161 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTEYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 5a4t C 2.15 BS01 AJG C 1 I165 V173 A186 F238 E239 M240 L241 S242 L294 V306 I31 V39 A52 F104 E105 M106 L107 S108 L160 V172 2.7.12.1 Q13627 VYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFWNLKKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 5a4t D 2.15 BS01 AJG D 1 I165 A186 E239 M240 L241 S242 L294 I32 A53 E106 M107 L108 S109 L161 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKYKPPGTRKLHNILGVETGGPGGGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 5a4u A 2.00 BS01 I3A A 1 I99 G103 Y151 R154 L161 A162 T169 I98 G102 Y150 R153 L160 A161 T168 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4u B 2.00 BS01 I3A B 1 I99 I102 G103 V150 Y151 R154 L161 A162 T169 I97 I100 G101 V148 Y149 R152 L159 A160 T167 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4u C 2.00 BS02 I3A C 2 Y97 A98 A101 Y96 A97 A100 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4u D 2.00 BS01 I3A C 3 Q73 Y74 H77 Q72 Y73 H76 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4u E 2.00 BS01 I3A E 1 I99 G103 V150 Y151 R154 L161 A162 T169 I98 G102 V149 Y150 R153 L160 A161 T168 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4u E 2.00 BS02 I3A F 1 A70 Q73 Y74 H77 A69 Q72 Y73 H76 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4u F 2.00 BS02 I3A F 1 I94 Y97 A98 A101 I92 Y95 A96 A99 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4v A 2.38 BS01 QUE B 1 H77 I94 Y97 A98 A101 H76 I93 Y96 A97 A100 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4v B 2.38 BS01 QUE B 1 Q73 H77 Y97 Q71 H75 Y95 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4v D 2.38 BS01 QUE D 1 H77 I94 Y97 A101 H76 I93 Y96 A100 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4v E 2.38 BS01 QUE F 1 Q73 Y74 H77 Y97 Q72 Y73 H76 Y96 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4v F 2.38 BS01 QUE F 1 Q73 H77 I94 Y97 A101 Q71 H75 I92 Y95 A99 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4w A 2.25 BS01 QCT A 1 I99 I102 G103 V150 Y151 R154 L161 T169 I98 I101 G102 V149 Y150 R153 L160 T168 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4w A 2.25 BS02 QCT A 2 Q73 H77 S91 K92 I94 Y97 A101 Q72 H76 S90 K91 I93 Y96 A100 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4w A 2.25 BS03 QCT B 1 S48 R49 F52 K64 F66 S47 R48 F51 K63 F65 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4w B 2.25 BS01 QCT A 1 S48 R49 P51 F52 K64 F66 S46 R47 P49 F50 K62 F64 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4w B 2.25 BS03 QCT B 1 I99 G103 V150 R154 L161 T169 I97 G101 V148 R152 L159 T167 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4w C 2.25 BS01 QCT C 1 G103 V150 R154 L161 T169 G102 V149 R153 L160 T168 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4w C 2.25 BS03 QCT D 1 S48 R49 K64 F66 S47 R48 K63 F65 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a4w E 2.25 BS01 QCT E 1 I99 I102 G103 V150 R154 L161 T169 I98 I101 G102 V149 R153 L160 T168 2.5.1.18 P46422 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a54 A 2.63 BS01 5PW A 1 I165 K188 F238 E239 L241 L294 V306 I32 K55 F105 E106 L108 L161 V173 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTEYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 5a54 B 2.63 BS01 5PW B 1 I165 A186 F238 E239 M240 L241 L294 V306 I33 A54 F106 E107 M108 L109 L162 V174 2.7.12.1 Q13627 RKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK 5a54 C 2.63 BS01 5PW C 1 I165 A186 F238 E239 L241 S242 L294 I31 A52 F104 E105 L107 S108 L160 2.7.12.1 Q13627 VYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFWNLKKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 5a54 D 2.63 BS01 5PW D 1 I165 A186 K188 F238 E239 M240 L241 L294 I32 A53 K55 F105 E106 M107 L108 L161 2.7.12.1 Q13627 KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKYKPPGTRKLHNILGVETGGPGGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 5a5d A 1.74 BS01 FE A 1 Q98 H227 Y288 Q77 H206 Y267 Q0P8Q4 AMLPISMSDEGDSFLVKDSLGENKIPKNPSKVVILDLGILDTFDALKLNDKVVGVPAKNLPKYLQQFKNKPSVGGVQQVDFEAINALKPDLIIISGRQSKFYDKLKEIAPTLFVGLDNANFLSSFENNVLSVAKLYGLEKEALEKISDIKNEIEKAKSIVDEDKKALIILTNSNKISAFGPQSRFGIIHDVLGINAVDENIKVGTHGKSINSEFILEKNPDYIFVVDRNVILGNKERAQGILDNALVAKTKAAQNKKIIYLDPEYWYLASGNGLESLKTMILEIKNAVK 5a5k A 2.77 BS01 7WB A 1 I99 I102 Y151 R154 I97 I100 Y149 R152 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a5k B 2.77 BS01 7WB B 1 I99 I102 G103 Y151 R154 I97 I100 G101 Y149 R152 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a5k C 2.77 BS01 7WB C 1 I99 I102 G103 V106 Y151 R154 I97 I100 G101 V104 Y149 R152 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a5k G 2.77 BS01 7WB G 1 I99 I102 V150 R154 I97 I100 V148 R152 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a5k H 2.77 BS01 7WB H 1 I99 I102 G103 V106 R154 I97 I100 G101 V104 R152 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a5k I 2.77 BS01 7WB I 1 I99 I102 V150 Y151 R154 I97 I100 V148 Y149 R152 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a5k L 2.77 BS01 7WB I 1 P51 F66 P49 F64 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a5k O 2.77 BS01 7WB O 1 I99 I102 Y151 R154 L161 I94 I97 Y142 R145 L152 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYETNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a5k R 2.77 BS01 7WB R 1 I99 I102 G103 Y151 R154 L161 I97 I100 G101 Y149 R152 L159 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5a5k T 2.77 BS01 7WB T 1 I102 V150 Y151 R154 I99 V146 Y147 R150 2.5.1.18 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFERPRVNEWVAEITKRPASEKV 5a5k V 2.77 BS01 7WB V 1 I99 I102 G103 R154 I97 I100 G101 R152 P46422 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 5aqd A 2.12 BS01 PEB A 1 A72 N73 F78 K81 C82 R84 D85 H88 Y89 W108 V116 Y117 L120 L122 P123 Y127 A72 N73 F78 K81 C82 R84 D85 H88 Y89 W108 V116 Y117 L120 L122 P123 Y127 A0A0E3W010 27068646 MKSVVTTVIAAADAAGRFPSSSDLESVQGSIQRSAARLEAAEKLAGNIDAVAQEAYNACIQKYPYLNNSGEANSTDTFKAKCLRDVKHYMRLIQYSLVVGGTGPLDEWGIAGQREVYRALGLPTAPYVEALSFARNRGCAPRDMSAQALTEYNALLDYAINSLS 5aqd A 2.12 BS02 PEB A 2 K43 L44 N47 V51 E54 R137 G138 C139 R142 D143 M144 Y152 K43 L44 N47 V51 E54 R137 G138 C139 R142 D143 M144 Y152 A0A0E3W010 27068646 MKSVVTTVIAAADAAGRFPSSSDLESVQGSIQRSAARLEAAEKLAGNIDAVAQEAYNACIQKYPYLNNSGEANSTDTFKAKCLRDVKHYMRLIQYSLVVGGTGPLDEWGIAGQREVYRALGLPTAPYVEALSFARNRGCAPRDMSAQALTEYNALLDYAINSLS 5aqd A 2.12 BS03 PEB M 1 L24 E25 Q28 L24 E25 Q28 A0A0E3W010 27068646 MKSVVTTVIAAADAAGRFPSSSDLESVQGSIQRSAARLEAAEKLAGNIDAVAQEAYNACIQKYPYLNNSGEANSTDTFKAKCLRDVKHYMRLIQYSLVVGGTGPLDEWGIAGQREVYRALGLPTAPYVEALSFARNRGCAPRDMSAQALTEYNALLDYAINSLS 5aqd A 2.12 BS04 PEB P 1 R33 Q147 R33 Q147 A0A0E3W010 27068646 MKSVVTTVIAAADAAGRFPSSSDLESVQGSIQRSAARLEAAEKLAGNIDAVAQEAYNACIQKYPYLNNSGEANSTDTFKAKCLRDVKHYMRLIQYSLVVGGTGPLDEWGIAGQREVYRALGLPTAPYVEALSFARNRGCAPRDMSAQALTEYNALLDYAINSLS 5aqd D 2.12 BS01 PEB D 1 L66 A72 N73 F78 K81 C82 R84 D85 H88 Y89 W108 V116 Y117 L120 L122 P123 P126 Y127 L66 A72 N73 F78 K81 C82 R84 D85 H88 Y89 W108 V116 Y117 L120 L122 P123 P126 Y127 A0A0E3W010 27068646 MKSVVTTVIAAADAAGRFPSSSDLESVQGSIQRSAARLEAAEKLAGNIDAVAQEAYNACIQKYPYLNNSGEANSTDTFKAKCLRDVKHYMRLIQYSLVVGGTGPLDEWGIAGQREVYRALGLPTAPYVEALSFARNRGCAPRDMSAQALTEYNALLDYAINSLS 5aqd K 2.12 BS01 PEB K 1 A72 N73 F78 K81 C82 R84 D85 H88 Y89 W108 V116 L120 L122 P123 P126 Y127 A72 N73 F78 K81 C82 R84 D85 H88 Y89 W108 V116 L120 L122 P123 P126 Y127 A0A0E3W010 27068646 MKSVVTTVIAAADAAGRFPSSSDLESVQGSIQRSAARLEAAEKLAGNIDAVAQEAYNACIQKYPYLNNSGEANSTDTFKAKCLRDVKHYMRLIQYSLVVGGTGPLDEWGIAGQREVYRALGLPTAPYVEALSFARNRGCAPRDMSAQALTEYNALLDYAINSLS 5aqd K 2.12 BS04 PEB W 1 L24 Q28 L24 Q28 A0A0E3W010 27068646 MKSVVTTVIAAADAAGRFPSSSDLESVQGSIQRSAARLEAAEKLAGNIDAVAQEAYNACIQKYPYLNNSGEANSTDTFKAKCLRDVKHYMRLIQYSLVVGGTGPLDEWGIAGQREVYRALGLPTAPYVEALSFARNRGCAPRDMSAQALTEYNALLDYAINSLS 5aqd M 2.12 BS01 PEB B 1 I65 Y72 P73 N74 M77 I65 Y72 P73 N74 M77 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd M 2.12 BS02 PEB M 2 M57 L64 N70 C71 R75 R76 A79 C80 R82 D83 I86 R106 L111 T114 Y115 L118 V120 S124 T125 M57 L64 N70 C71 R75 R76 A79 C80 R82 D83 I86 R106 L111 T114 Y115 L118 V120 S124 T125 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd M 2.12 BS03 PEB M 1 N33 R34 L36 D37 I140 K141 D142 S158 P159 V160 V161 R164 C165 N33 R34 L36 D37 I140 K141 D142 S158 P159 V160 V161 R164 C165 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd M 2.12 BS04 PEB M 3 N45 C48 D52 A55 G56 C59 I131 A134 Q135 A138 H139 P144 S145 R148 A149 K152 L153 R154 N45 C48 D52 A55 G56 C59 I131 A134 Q135 A138 H139 P144 S145 R148 A149 K152 L153 R154 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd N 2.12 BS02 PEB N 2 M57 N70 C71 R75 R76 A79 C80 R82 D83 I86 Y90 R106 L111 T114 L118 V120 S124 T125 M57 N70 C71 R75 R76 A79 C80 R82 D83 I86 Y90 R106 L111 T114 L118 V120 S124 T125 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd N 2.12 BS04 PEB N 3 N45 C48 D52 A55 G56 C59 E60 R127 A134 Q135 A138 H139 P144 S145 R148 A149 K152 L153 R154 N45 C48 D52 A55 G56 C59 E60 R127 A134 Q135 A138 H139 P144 S145 R148 A149 K152 L153 R154 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd Q 2.12 BS01 PEB D 1 I58 I65 Y72 P73 N74 M77 I58 I65 Y72 P73 N74 M77 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd Q 2.12 BS04 PEB Q 3 N45 C48 D52 A55 G56 C59 E60 R127 I131 A134 Q135 H139 P144 S145 R148 A149 K152 L153 R154 N45 C48 D52 A55 G56 C59 E60 R127 I131 A134 Q135 H139 P144 S145 R148 A149 K152 L153 R154 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd R 2.12 BS02 PEB R 2 M57 N70 C71 R75 R76 A79 C80 R82 D83 I86 R106 L111 L118 V120 P121 S124 T125 M57 N70 C71 R75 R76 A79 C80 R82 D83 I86 R106 L111 L118 V120 P121 S124 T125 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd S 2.12 BS02 PEB S 2 M57 L64 N70 C71 R75 R76 A79 C80 R82 D83 I86 R106 L111 L118 V120 P121 S124 T125 M57 L64 N70 C71 R75 R76 A79 C80 R82 D83 I86 R106 L111 L118 V120 P121 S124 T125 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5aqd T 2.12 BS02 PEB T 2 M57 N70 C71 R75 R76 A79 C80 R82 D83 I86 R106 L111 T114 Y115 L118 V120 S124 T125 M57 N70 C71 R75 R76 A79 C80 R82 D83 I86 R106 L111 T114 Y115 L118 V120 S124 T125 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5avp A 2.90 BS01 MN A 1 H110 H112 K115 E117 H192 H105 H107 K110 E112 H187 5.3.1.- D2S5K0 ARTSVTRREYDEWLNEAAALGRALRYPVRPEMVNDSAGIVFGEDQYDAFENGLWSREPYEAMVIFESLNEPAVDGLPAAGAPFAEYSGLCDKLMIVHPGKFCPPHYHQRKTESYEVVLGEMELFYSPKPVQVGEEEVLSFTGMHEGSPWPDGVALPIGREESYAALTSYRRLRVGDPKFVMHRKHLHAFRCPADSDVPLVVREVSTYSHEPAPLPDWAGLHDNSFVAAAANSGRLRTAIQ 5b4k A 2.90 BS02 6DT A 1 Y514 L665 V668 I682 Y683 F686 P702 M703 K708 E711 G715 Q716 F719 Y70 L221 V224 I238 Y239 F242 P258 M259 K264 E267 G271 Q272 F275 3.1.4.17 Q9Y233 27301679 EWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5b4l A 2.40 BS03 6DW A 1 Y514 H515 L625 L665 I682 Y683 F686 P702 M703 K708 E711 V712 G715 Q716 F719 Y70 H71 L181 L221 I238 Y239 F242 P258 M259 K264 E267 V268 G271 Q272 F275 3.1.4.17 Q9Y233 27301679 EWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5b5b A 2.00 BS01 III C 1 I238 K242 D253 Q255 I256 V257 L259 K260 P412 E416 I67 K71 D82 Q84 I85 V86 L88 K89 P241 E245 P13053 27294600 SPLKDSLRPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN 5b5b A 2.00 BS02 AKX A 1 Y143 Y147 L223 L226 A227 V230 S233 R270 S271 S274 W282 C284 D295 V296 A299 H393 Q396 Y397 V414 Y30 Y34 L52 L55 A56 V59 S62 R99 S100 S103 W111 C113 D124 V125 A128 H222 Q225 Y226 V243 P13053 27294600 SPLKDSLRPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN 5b5b D 2.00 BS01 III F 1 I238 K242 Q255 I256 L259 K260 P412 E416 N420 I58 K62 Q75 I76 L79 K80 P232 E236 N240 P13053 27294600 KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN 5bn2 A 1.30 BS01 CA A 1 S149 T152 P153 G154 S136 T139 P140 G141 F2QVG4 EIKPEDAPYITNAYKPAYARWGFGSDSVRNHFIAMSGEFVGTFLFLWSAFVIAQIANQAPETPDGGSNPAQLIMISFGFGFGVMVGVFITYRVSGGNLNPAVTLALVLARAIPPFRGILMAFTQIVAGMAAAGAASAMTPGEIAFANALGGGASRTRGLFLEAFGTAILCLTVLMLAVEKHRATWFAPFVIGIALLIAHLICIYYTGAGLNPARSFGPAVAARSFPNYHWIYWLGPILGAFLAYSIWQMWKWLNYQTTNP 5bxo A 1.33 BS01 III C 1 R525 S527 F532 G535 Y536 K557 L560 N565 Y569 H571 D589 W591 F593 E598 K602 R39 S41 F46 G49 Y50 K71 L74 N79 Y83 H85 D103 W105 F107 E112 K116 2.4.2.30 Q9H2K2 SGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGD 5bzc A 1.95 BS01 4WT A 1 N29 V30 H39 E41 V153 N154 R155 N6 V7 H16 E18 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzf A 2.77 BS01 4X3 A 1 N29 V30 T31 E41 N154 R155 N6 V7 T8 E18 N131 R132 P15379 QQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRASKKGEYRTHQEDI 5bzh A 1.95 BS01 4X1 A 1 N29 V30 E41 R82 V153 N154 R155 N6 V7 E18 R59 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzk A 1.40 BS01 4WP A 1 N29 V30 T31 H39 T80 C81 R82 V153 N154 R155 N6 V7 T8 H16 T57 C58 R59 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzl A 1.23 BS01 4WO A 1 N29 V30 T31 H39 E41 T80 R82 V153 N154 R155 N6 V7 T8 H16 E18 T57 R59 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzm A 1.25 BS01 4X8 A 1 N29 V30 T31 E41 G44 R82 V153 N154 R155 N6 V7 T8 E18 G21 R59 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzn A 1.23 BS02 4XD A 2 D145 G146 P147 D122 G123 P124 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzo A 1.22 BS01 4XC A 1 N29 V30 T31 E41 R82 V153 N154 R155 N6 V7 T8 E18 R59 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzq A 1.20 BS01 4XL A 1 N29 V30 T31 E41 C81 V153 N154 R155 N6 V7 T8 E18 C58 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzr A 1.15 BS01 4XM A 1 N29 V30 T31 C81 V153 N154 R155 N6 V7 T8 C58 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzs A 1.50 BS01 4XK A 1 N29 V30 T31 E41 C81 R82 V153 N154 R155 N6 V7 T8 E18 C58 R59 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5bzt A 1.25 BS01 4XJ A 1 N29 V30 T31 H39 E41 R82 V153 N154 R155 N6 V7 T8 H16 E18 R59 V130 N131 R132 P15379 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 5c3m A 3.06 BS01 MN A 1 N150 C172 N201 H202 Y316 N146 C168 N197 H198 Y288 3.2.1.86 W8R9V4 LKMATIGGGSSYTPELVEGLIKRYHELPVGELWLVDIPEGKEKLEIVGALAKRMVEKAGVPIEIHLTLDRRRALEGADFVTTQFRVGGLEARAKDERIPLKYGVIGQETNGPGGLFKGLRTIPVILDIIRDMEELCPDAWLINFTNPAGMVTEAVLRYTKQEKVVGLCNVPIGMRMGVAKLLGVDADRVHIDFAGLNHMVFGLHVYLDGVEVTEKVIDLVAHPLGWEPDFLKGLKVLPCPYHRYYYQTDKMLAEELEAAKTKGTRAEVVQQLEKELFELYKDPGGAYYSDAACSLISSIYNDKRDIQPVNTRNNGAIASIPPESAVEVNCVITKDGPKPIAVGDLPVAVRGLVQQIKSFERVAAEAAVTGDYQTALVAMTINPLVPSDTIAKQMLDEMLEAHKEHLPQFF 5c3m B 3.06 BS01 MN B 1 N150 C172 H202 Y316 N146 C168 H198 Y289 3.2.1.86 W8R9V4 LKMATIGGGSSYTPELVEGLIKRYHELPVGELWLVDIPEGKEKLEIVGALAKRMVEKAGVPIEIHLTLDRRRALEGADFVTTQFRVGGLEARAKDERIPLKYGVIGQETNGPGGLFKGLRTIPVILDIIRDMEELCPDAWLINFTNPAGMVTEAVLRYTKQEKVVGLCNVPIGMRMGVAKLLGVDADRVHIDFAGLNHMVFGLHVYLDGVEVTEKVIDLVAHPLGWEPDFLKGLKVLPCPYHRYYYQTDKMLAEELEAAKTKGTRAEVVQQLEKELFELYKDPRGGAYYSDAACSLISSIYNDKRDIQPVNTRNNGAIASIPPESAVEVNCVITKDGPKPIAVGDLPVAVRGLVQQIKSFERVAAEAAVTGDYQTALVAMTINPLVPSDTIAKQMLDEMLEAHKEHLPQFF 5c4m A 1.30 BS02 GDP A 1 A15 C16 G17 K18 T19 C20 F30 V35 K118 D120 L121 S160 A161 K162 A13 C14 G15 K16 T17 C18 F28 V33 K116 D118 L119 S158 A159 K160 P61586 AIRKKLVIVGDGACGKTCLLIVNSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQA 5c58 B 2.80 BS01 HEM B 1 H32 T33 N34 G35 V37 S42 F45 Y55 Y75 L77 H83 H133 Y137 M140 H31 T32 N33 G34 V36 S41 F44 Y54 Y74 L76 H82 H132 Y136 M139 Q54450 AFSVNYDSSFGGYSIHDYLGQWASTFGDVNHTNGNVTDANSGGFYGGSLSGSQYAISSTANQVTAFVAGGNLTYTLFNEPAHTLYGQLDSLSFGDGLSGGDTSPYSIQVPDVSFGGLNLSSLQAQGHDGVVHQVVYGLMSGDTGALETALNGILDDYGLSVNSTFDQVAAATA 5c5a A 1.15 BS01 NUT A 1 L54 G58 Q59 I61 M62 Q72 H73 V75 F91 V93 H96 I99 Y100 L35 G39 Q40 I42 M43 Q53 H54 V56 F72 V74 H77 I80 Y81 6.3.2.- Q00987 PASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVN 5c71 A 2.62 BS01 CBW A 1 D414 V447 L449 Y469 Y473 T474 D404 V437 L439 Y459 Y463 T464 MLKPQQTTTRDLISLDGLWKFALASDDNNTQPWTSQLKTSLECPVPASYNDIFADSKIHDHVGWVYYQRDVIVPKGWSEERYLVRCEAATHHGRIYVNGNLVADHVGGYTPFEADITDLVAAGEQFRLTIAVDNELTYQTIPPGKVEILEATGKKVQTYQHDFYNYAGLARSVWLYSVPQQHIQDITVRTDVQGTTGLIDYNVVASTTQGTIQVAVIDEDGTTVATSSGSNGTIHIPSVHLWQPGAAYLYQLHASIIDSSKKTIDTYKLATGIRTVKVQGTQFLINDKPFYFTGFGKHEDTNIRGKGHDDAYMVHDFQLLHWMGANSFRTSHYPYAEEVMEYADRQGIVVIDETPAVGLAFSPATFSPDRINNKTREAHAQAIRELIHRDKNHPSVVMWSIANDPASNEDGAREYFAPLPKLARQLDPTRPVTFANVGLATYKADRIADLFDVLCLNRYFGWYTQTAELDEAEAALEEELRGWTEKYDKPIVMTDYGADTVAGLHSVMVTPWSEEFQVEMLDMYHRVFDRFEAMAGEQVWNFADFQTAVGVSRVDGNKKGVFTRDRKPKAAAHLLRKRWTNLH 5c71 A 2.62 BS02 GCU A 1 D162 Y469 Y473 D505 W550 R563 N567 K569 D162 Y459 Y463 D495 W540 R553 N557 K559 MLKPQQTTTRDLISLDGLWKFALASDDNNTQPWTSQLKTSLECPVPASYNDIFADSKIHDHVGWVYYQRDVIVPKGWSEERYLVRCEAATHHGRIYVNGNLVADHVGGYTPFEADITDLVAAGEQFRLTIAVDNELTYQTIPPGKVEILEATGKKVQTYQHDFYNYAGLARSVWLYSVPQQHIQDITVRTDVQGTTGLIDYNVVASTTQGTIQVAVIDEDGTTVATSSGSNGTIHIPSVHLWQPGAAYLYQLHASIIDSSKKTIDTYKLATGIRTVKVQGTQFLINDKPFYFTGFGKHEDTNIRGKGHDDAYMVHDFQLLHWMGANSFRTSHYPYAEEVMEYADRQGIVVIDETPAVGLAFSPATFSPDRINNKTREAHAQAIRELIHRDKNHPSVVMWSIANDPASNEDGAREYFAPLPKLARQLDPTRPVTFANVGLATYKADRIADLFDVLCLNRYFGWYTQTAELDEAEAALEEELRGWTEKYDKPIVMTDYGADTVAGLHSVMVTPWSEEFQVEMLDMYHRVFDRFEAMAGEQVWNFADFQTAVGVSRVDGNKKGVFTRDRKPKAAAHLLRKRWTNLH 5c71 C 2.62 BS01 CBW C 1 D414 V447 G448 L449 Y469 Y473 D404 V437 G438 L439 Y459 Y463 MLKPQQTTTRDLISLDGLWKFALASDDNNTQPWTSQLKTSLECPVPASYNDIFADSKIHDHVGWVYYQRDVIVPKGWSEERYLVRCEAATHHGRIYVNGNLVADHVGGYTPFEADITDLVAAGEQFRLTIAVDNELTYQTIPPGKVEILEATGKKVQTYQHDFYNYAGLARSVWLYSVPQQHIQDITVRTDVQGTTGLIDYNVVASTTQGTIQVAVIDEDGTTVATSSGSNGTIHIPSVHLWQPGAAYLYQLHASIIDSSKKTIDTYKLATGIRTVKVQGTQFLINDKPFYFTGFGKHEDTNIRGKGHDDAYMVHDFQLLHWMGANSFRTSHYPYAEEVMEYADRQGIVVIDETPAVGLAFSPATFSPDRINNKTREAHAQAIRELIHRDKNHPSVVMWSIANDPASNEDGAREYFAPLPKLARQLDPTRPVTFANVGLATYKADRIADLFDVLCLNRYFGWYTQTAELDEAEAALEEELRGWTEKYDKPIVMTDYGADTVAGLHSVMVTPWSEEFQVEMLDMYHRVFDRFEAMAGEQVWNFADFQTAVGVSRVDGNKKGVFTRDRKPKAAAHLLRKRWTNLH 5c71 C 2.62 BS02 GCU C 1 D162 H332 Y469 Y473 W550 R563 N567 K569 D162 H332 Y459 Y463 W540 R553 N557 K559 MLKPQQTTTRDLISLDGLWKFALASDDNNTQPWTSQLKTSLECPVPASYNDIFADSKIHDHVGWVYYQRDVIVPKGWSEERYLVRCEAATHHGRIYVNGNLVADHVGGYTPFEADITDLVAAGEQFRLTIAVDNELTYQTIPPGKVEILEATGKKVQTYQHDFYNYAGLARSVWLYSVPQQHIQDITVRTDVQGTTGLIDYNVVASTTQGTIQVAVIDEDGTTVATSSGSNGTIHIPSVHLWQPGAAYLYQLHASIIDSSKKTIDTYKLATGIRTVKVQGTQFLINDKPFYFTGFGKHEDTNIRGKGHDDAYMVHDFQLLHWMGANSFRTSHYPYAEEVMEYADRQGIVVIDETPAVGLAFSPATFSPDRINNKTREAHAQAIRELIHRDKNHPSVVMWSIANDPASNEDGAREYFAPLPKLARQLDPTRPVTFANVGLATYKADRIADLFDVLCLNRYFGWYTQTAELDEAEAALEEELRGWTEKYDKPIVMTDYGADTVAGLHSVMVTPWSEEFQVEMLDMYHRVFDRFEAMAGEQVWNFADFQTAVGVSRVDGNKKGVFTRDRKPKAAAHLLRKRWTNLH 5c7y A 1.75 BS01 ZFR A 1 D31 G32 L33 S102 L132 L135 M154 W183 Y187 P188 I191 P192 H242 F243 D30 G31 L32 S101 L131 L134 M153 W182 Y186 P187 I190 P191 H241 F242 Q8NKB0 RTRSTISTPNGITWYYEQEGTGPDIVLVPDGLGECQMFDSSVSQIAAQGFRVTTFDMPGMSRSAKAPAETYTEVTAQKLASYVISILDALDIKHATVWGCSSGASTVVALLLGYPDRIRNAMCHELPTKLLDHLSNTAVLEDEEISNILANVMLNDVSGGSEAWQALGVEVHARLHKNYPVWARGYPRTIPPSAPVQDVEALRGKPLDWTVGAATPTESFFDNIVTATKAGVNIGLLPGMHFPYVSHPDVFAKYVVETTQKHLWNS 5c7y B 1.75 BS01 ZFR B 1 D31 G32 S102 L132 L135 M154 V158 W183 Y187 P188 I191 P192 H242 F243 D30 G31 S101 L131 L134 M153 V157 W182 Y186 P187 I190 P191 H241 F242 Q8NKB0 RTRSTISTPNGITWYYEQEGTGPDIVLVPDGLGECQMFDSSVSQIAAQGFRVTTFDMPGMSRSAKAPAETYTEVTAQKLASYVISILDALDIKHATVWGCSSGASTVVALLLGYPDRIRNAMCHELPTKLLDHLSNTAVLEDEEISNILANVMLNDVSGGSEAWQALGVEVHARLHKNYPVWARGYPRTIPPSAPVQDVEALRGKPLDWTVGAATPTESFFDNIVTATKAGVNIGLLPGMHFPYVSHPDVFAKYVVETTQKHLWNSS 5c81 A 1.80 BS01 ZFR A 1 D31 G32 S102 P128 K130 L132 L135 M154 W183 Y187 P188 I191 P192 H242 F243 D30 G31 S101 P127 K129 L131 L134 M153 W182 Y186 P187 I190 P191 H241 F242 Q8NKB0 RTRSTISTPNGITWYYEQEGTGPDIVLVPDGLGECQMFDSSVSQIAAQGFRVTTFDMPGMSRSAKAPAETYTEVTAQKLASYVISILDALDIKHATVWGCSSGASTVVALLLGYPDRIRNAMCHELPTKLLDHLSNTAVLEDEEISNILANVMLNDVSGGSEAWQALGVEVHARLHKNYPVWARGYPRTIPPSAPVQDVEALRGKPLDWTVGAATPTESFFDNIVTATKAGVNIGLLPGMHFPYVSHPDVFAKYVVETTQKHLWNSS 5c9z A 2.36 BS01 SFG A 1 L315 Y324 K333 Y334 G365 A366 G367 P370 L371 E392 K393 S418 D419 M420 R421 E435 L436 C449 L303 Y312 K321 Y322 G353 A354 G355 P358 L359 E380 K381 S406 D407 M408 R409 E423 L424 C437 2.1.1.-,2.1.1.125 O14744 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 5c9z A 2.36 BS02 4Z2 A 1 F300 Q309 L319 V326 F327 K333 E435 L437 G438 S439 E444 V503 F577 S578 W579 F580 F288 Q297 L307 V314 F315 K321 E423 L425 G426 S427 E432 V491 F565 S566 W567 F568 2.1.1.-,2.1.1.125 O14744 RVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 5cae A 2.20 BS01 COA A 1 G22 T24 G25 K26 Q27 P48 K50 Y79 V80 P81 P82 I103 T104 E105 N131 C132 P133 I145 G21 T23 G24 K25 Q26 P47 K49 Y78 V79 P80 P81 I102 T103 E104 N130 C131 P132 I144 6.2.1.4,6.2.1.5 O19069 SYTASRKHLYVDKNTKVICQGFTGKQGTFHSQQALEYGTNLVGGTTPGKGGKTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAAAAINEAIDAEVPLVVCITEGIPQQDMVRVKHRLLRQGKTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFTDCLEIFLNDPATEGIILIGEIGGNAEENAAEFLKQHNSGPKSKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKITALQSAGVVVSMSPAQLGTTIYKEFEKRK 5cho A 2.37 BS01 FAD A 1 H59 M61 T62 A63 N64 S65 C79 V80 E81 D83 A84 A85 M86 Y112 A113 R115 R117 R119 Y181 F186 H30 M32 T33 A34 N35 S36 C50 V51 E52 D54 A55 A56 M57 Y83 A84 R86 R88 R90 Y152 F157 M9QXS1 LLRDSRSLRGIFSSFATGVTVVTVGGDSPHAMTANSFTSVSLDPPLILVCVECDAAMHGSLLEVGSFGVSVLAADQQHVALLYANRWRPRDPTQFDRPGWARGARTGAPLARGALAWFECALWRAYDAGDHSIFVGRLLTAERHDRRDALVYHSGQFRGLPDRAP 5cho E 2.37 BS01 FAD E 1 H59 M61 T62 A63 N64 S65 C79 V80 E81 A84 A85 M86 A113 R115 R117 R119 H160 Y181 F186 H27 M29 T30 A31 N32 S33 C47 V48 E49 A52 A53 M54 A81 R83 R85 R87 H128 Y149 F154 M9QXS1 DSRSLRGIFSSFATGVTVVTVGGDSPHAMTANSFTSVSLDPPLILVCVECDAAMHGSLLEVGSFGVSVLAADQQHVALLYANRWRPRDPTQFDRPGWARGARTGAPLARGALAWFECALWRAYDAGDHSIFVGRLLTAERHDRRDALVYHSGQFRGLPDRA 5cho G 2.37 BS01 FAD G 1 H59 M61 T62 A63 N64 S65 C79 E81 A84 A85 M86 Y112 A113 R115 R117 R119 H160 Y181 F186 H27 M29 T30 A31 N32 S33 C47 E49 A52 A53 M54 Y80 A81 R83 R85 R87 H128 Y149 F154 M9QXS1 DSRSLRGIFSSFATGVTVVTVGGDSPHAMTANSFTSVSLDPPLILVCVECDAAMHGSLLEVGSFGVSVLAADQQHVALLYANRWRPRDPTQFDRPGWARGARTGAPLARGALAWFECALWRAYDAGDHSIFVGRLLTAERHDRRDALVYHSGQFRGLPDR 5cht A 2.80 BS01 ZN A 1 C175 C178 C226 C229 C133 C136 C184 C187 3.4.19.- Q9WTV6 GPGDSPHGLVGLHNIGQTCCLNSLLQVFMMNMDFRMILKRITVPRSAEERKRSVPFQLLLLLEKMQDSRQKAVLPTELVQCLQKYNVPLFVQHDAAQLYLTIWNLTKDQITDTDLTERLQGLFTIWTQESLICVGCTAESSRRSKLLTLSLPLFDKDAKPLKTLEDALRCFVQPKELASSDMCCESCGEKTPWKQVLKLTHLPQTLTIHLMRFSARTEKICHSVNFPQSLDFSQVEIHYELFAVIAHVGMADFGHYCAYIRNPVDGKWFCFNDSHVCWVTWKDVQCTYGNHRYRWRETAYLLVYTKTG 5cht A 2.80 BS02 ZN A 2 H334 C336 H275 C277 3.4.19.- Q9WTV6 GPGDSPHGLVGLHNIGQTCCLNSLLQVFMMNMDFRMILKRITVPRSAEERKRSVPFQLLLLLEKMQDSRQKAVLPTELVQCLQKYNVPLFVQHDAAQLYLTIWNLTKDQITDTDLTERLQGLFTIWTQESLICVGCTAESSRRSKLLTLSLPLFDKDAKPLKTLEDALRCFVQPKELASSDMCCESCGEKTPWKQVLKLTHLPQTLTIHLMRFSARTEKICHSVNFPQSLDFSQVEIHYELFAVIAHVGMADFGHYCAYIRNPVDGKWFCFNDSHVCWVTWKDVQCTYGNHRYRWRETAYLLVYTKTG 5ciz A 5.01 BS02 NUC E 1 D138 V139 C178 S179 R180 E181 T182 R185 G200 K201 D132 V133 C172 S173 R174 E175 T176 R179 G194 K195 P0ACJ8 TDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR 5ciz A 5.01 BS03 CMP A 1 V49 L61 I70 G71 E72 L73 R82 S83 A84 V86 T127 V43 L55 I64 G65 E66 L67 R76 S77 A78 V80 T121 P0ACJ8 TDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR 5cx7 A 1.97 BS01 HEM A 1 F14 H18 T21 R22 V25 W50 F5 H9 T12 R13 V16 W41 VALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWRMPDALLVSSELAPKKAWTAVAMKTATHELSDVVQPGAALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDMDIAQTAIAAINVGTHQ 5cx7 B 1.97 BS01 HEM A 1 F14 H18 T21 R22 W50 F5 H9 T12 R13 W41 VALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWRMPDALLVSSELAPKKAWTAVAMKTATHELSDVVQPGAALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDMDIAQTAIAAINVGTHQ 5cx7 D 1.97 BS01 HEM C 1 F14 H18 R22 W50 F5 H9 R13 W41 VALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWRMPDALLVSSELAPKKAWTAVAMKTATHELSDVVQPGAALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDMDIAQTAIAAINVGTHQ 5cx7 H 1.97 BS02 MG H 1 E26 Q29 E17 Q20 VALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWRMPDALLVSSELAPKKAWTAVAMKTATHELSDVVQPGAALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDMDIAQTAIAAINVGTHQ 5cx7 O 1.97 BS01 HEM O 1 F14 H18 R22 V48 W50 F5 H9 R13 V39 W41 VALSFHDLHQLTRAAVERAQQLQVPVVVSIVDAHGTETVTWRMPDALLVSSELAPKKAWTAVAMKTATHELSDVVQPGAALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDMDIAQTAIAAINVGTHQ 5d8c A 2.25 BS01 NUC C 1 Y17 T18 F21 Y22 S61 L62 Y17 T18 F21 Y22 S61 L62 P44558 27307602 MTYTTAKAAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNTGMSLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAKALGSVKAV 5d8c A 2.25 BS02 NUC D 1 T5 A6 R20 K24 R33 G37 N38 R39 T5 A6 R20 K24 R33 G37 N38 R39 P44558 27307602 MTYTTAKAAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNTGMSLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAKALGSVKAV 5d8z A 2.70 BS01 CBI A 1 E164 W202 Y237 D241 N242 S243 E143 W181 Y216 D220 N221 S222 26992795 LQFAGVNIAGFDFGCGSDGTCNASGAWPPLTQYYGADGAGQMKHFVDDDGFNVFRLPVGWQFITDGVAGGDIDEDNWAEYDALVQACLDAGASCIVDVHNYARFNGEIIGQGGPTNQDFAALWSSIAAKYADNDKIIFGVMNEPHDVPDINLWADSVQAAVTAIRQAGATSQIILLPGNNWTSAETFVSNGSADALKKVTNPDGSVTNLIFDVHKYLDSDNSGTHEECTTNNIDNAWAPLAEWLRCNGRQAFNTETGGGNVASCETFMCQQVAYQNANSDVFLGYVGWAAGNFYQGYVLGEVPTDTNGVWTDTALVSACLAPNA 5d8z B 2.70 BS01 CBI B 1 E164 W202 Y237 D241 N242 E143 W181 Y216 D220 N221 26992795 LQFAGVNIAGFDFGCGSDGTCNASGAWPPLTQYYGADGAGQMKHFVDDDGFNVFRLPVGWQFITDGVAGGDIDEDNWAEYDALVQACLDAGASCIVDVHNYARFNGEIIGQGGPTNQDFAALWSSIAAKYADNDKIIFGVMNEPHDVPDINLWADSVQAAVTAIRQAGATSQIILLPGNNWTSAETFVSNGSADALKKVTNPDGSVTNLIFDVHKYLDSDNSGTHEECTTNNIDNAWAPLAEWLRCNGRQAFNTETGGGNVASCETFMCQQVAYQNANSDVFLGYVGWAAGNFYQGYVLGEVPTDTNGVWTDTALVSACLAPNA 5dhz H 4.30 BS01 III M 1 W33 Y52 G54 E58 W59 W33 Y52 G54 E58 W59 27265851 QEQLVESGGRLVTPGTALTLTCKVSGFSLSGFWLNWVRQAPGKGLEWVGAIYRGSGSEWYASWAKGRFTISDTSTTVTLKLTSPTTEDTATYFCAADTTDNGYFTIWGPGTLVTVSS 5dhz H 4.30 BS02 III M 2 W59 T99 D100 N101 W59 T99 D100 N101 27265851 QEQLVESGGRLVTPGTALTLTCKVSGFSLSGFWLNWVRQAPGKGLEWVGAIYRGSGSEWYASWAKGRFTISDTSTTVTLKLTSPTTEDTATYFCAADTTDNGYFTIWGPGTLVTVSS 5dhz L 4.30 BS01 III M 1 A94 R98 A94 R98 27265851 ELVMTQTPSSVSEPVGGTVTIKCQASQSISSWLSWYQQKPGQPPKLLIYDASNLASGVPSRFMGSGSGTEYTLTISGVQREDAATYYCLGGYPAASYRTAFGGGTELEII 5dhz L 4.30 BS02 III M 3 I29 S30 S31 W32 Y92 A94 A95 S96 Y97 I29 S30 S31 W32 Y92 A94 A95 S96 Y97 27265851 ELVMTQTPSSVSEPVGGTVTIKCQASQSISSWLSWYQQKPGQPPKLLIYDASNLASGVPSRFMGSGSGTEYTLTISGVQREDAATYYCLGGYPAASYRTAFGGGTELEII 5e01 A 2.30 BS02 NUC D 1 T5 R20 K24 R33 N38 R39 T5 R20 K24 R33 N38 R39 P44558 27307602 MTYTTAKAAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNTGMSLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAKALGSVKAV 5e01 B 2.30 BS01 NUC C 1 T5 R20 K24 R33 G37 N38 R39 T6 R21 K25 R34 G38 N39 R40 P44558 27307602 AMTYTTAKAAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNTGMSLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAKALGSVKAV 5ebu A 2.60 BS01 FMN A 1 I41 A92 P93 I94 A95 S122 Q144 Y146 T172 K241 S263 H265 G266 R268 D296 S297 G298 R300 G319 R320 I34 A85 P86 I87 A88 S115 Q137 Y139 T165 K234 S256 H258 G259 R261 D289 S290 G291 R293 G312 R313 1.1.3.- Q44467 27302031 YNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIAAHGLAHATKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNRDILDEAKGDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQRYLRGTAEGMSLNNIFGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLFDNPYGYEY 5ebu A 2.60 BS02 PYR A 1 Y40 Y124 Y146 R181 L211 F215 H265 R268 Y33 Y117 Y139 R174 L204 F208 H258 R261 1.1.3.- Q44467 27302031 YNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIAAHGLAHATKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNRDILDEAKGDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQRYLRGTAEGMSLNNIFGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLFDNPYGYEY 5ebu B 2.60 BS01 FMN B 1 Y40 I41 P93 I94 A95 S122 Q144 Y146 T172 K241 S263 H265 G266 R268 D296 S297 G298 R300 G319 R320 Y33 I34 P86 I87 A88 S115 Q137 Y139 T165 K234 S256 H258 G259 R261 D289 S290 G291 R293 G312 R313 1.1.3.- Q44467 27302031 YNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIAAHGLAHATKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNRDILDEAKGDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQRYLRGTAEGMSLNNIFGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLFDNPYGYEY 5ebu C 2.60 BS02 PYR C 1 Y40 A95 Y124 Y146 R181 L211 H265 R268 Y33 A88 Y117 Y139 R174 L204 H258 R261 1.1.3.- Q44467 27302031 YNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIAAHGLAHATKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNRDILDEAKGDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQRYLRGTAEGMSLNNIFGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLFDNPYGYEY 5ebu D 2.60 BS02 PYR D 1 Y40 Y146 R181 H265 R268 Y35 Y141 R176 H244 R247 1.1.3.- Q44467 27302031 IEYNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIAAHGLAHATKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNRDILDEAKGDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLFDNPYGYEY 5ebu E 2.60 BS02 PYR E 1 Y40 Y146 R181 L211 F215 H265 R268 Y33 Y139 R174 L204 F208 H258 R261 1.1.3.- Q44467 27302031 YNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIAAHGLAHATKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNRDILDEAKGDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQRYLRGTAEGMSLNNIFGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLFDNPYGYEY 5ebu F 2.60 BS02 PYR F 1 Y40 A95 Y124 Y146 R181 L211 F215 H265 R268 Y33 A88 Y117 Y139 R174 L204 F208 H258 R261 1.1.3.- Q44467 27302031 YNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIAAHGLAHATKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNRDILDEAKGDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQRYLRGTAEGMSLNNIFGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLFDNPYGYEY 5ebu G 2.60 BS02 PYR G 1 Y40 A95 Y124 Y146 R181 H265 R268 Y33 A88 Y117 Y139 R174 H258 R261 1.1.3.- Q44467 27302031 YNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIAAHGLAHATKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNRDILDEAKGDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQRYLRGTAEGMSLNNIFGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLFDNPYGYEY 5ehr A 1.70 BS01 5OD A 1 T108 E110 R111 F113 H114 T218 T219 E249 E250 T253 L254 Q257 P491 K492 Q495 T94 E96 R97 F99 H100 T191 T192 E216 E217 T220 L221 Q224 P451 K452 Q455 3.1.3.48 Q06124 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESGDFVLSVRTGDSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETL 5emc A 2.30 BS01 NUC C 1 G449 C450 H451 Y452 K461 G12 C13 H14 Y15 K24 P04150 KLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNL 5emq B 2.30 BS01 NUC C 1 G458 S459 V462 F463 R466 R489 K490 P493 R496 G22 S23 V26 F27 R30 R53 K54 P57 R60 P04150 PKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLE 5eo7 A 2.30 BS01 SFU A 1 R25 E37 L69 I72 Y88 W94 R24 E36 L68 I71 Y87 W93 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 A 2.30 BS02 SFU A 2 R73 E85 Y95 G97 A98 L123 L125 W141 W146 R72 E84 Y94 G96 A97 L122 L124 W140 W145 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 A 2.30 BS03 SFU A 3 L117 R126 E138 M140 T150 I176 Y192 W198 L116 R125 E137 M139 T149 I175 Y191 W197 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 A 2.30 BS04 SFU A 4 F220 R230 Q242 C244 P274 L276 W294 F219 R229 Q241 C243 P273 L275 W293 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 A 2.30 BS05 SFU A 5 N22 L24 Y40 W44 W271 R277 E291 N21 L23 Y39 W43 W270 R276 E290 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 B 2.30 BS03 SFU B 3 R126 E138 M140 T150 P174 I176 Y192 W198 R125 E137 M139 T149 P173 I175 Y191 W197 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 B 2.30 BS04 SFU B 4 R230 Q242 C244 R255 P274 L276 W294 R229 Q241 C243 R254 P273 L275 W293 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 C 2.30 BS02 SFU C 2 R73 E85 Y95 G97 A98 L123 L125 W146 R72 E84 Y94 G96 A97 L122 L124 W145 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 C 2.30 BS03 SFU C 3 R126 E138 M140 T150 I176 Y192 W198 R125 E137 M139 T149 I175 Y191 W197 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 C 2.30 BS04 SFU C 4 R230 Q242 C244 L276 W294 R229 Q241 C243 L275 W293 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo7 C 2.30 BS05 SFU C 5 N22 L24 Y40 W44 W271 R277 E291 T293 N21 L23 Y39 W43 W270 R276 E290 T292 Q2UNX8 27318092 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo8 A 1.60 BS02 TFU A 2 R25 E37 L39 L69 I72 Y88 W94 R25 E37 L39 L69 I72 Y88 W94 Q2UNX8 27318092 MSTPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo8 A 1.60 BS05 TFU A 5 W166 Y168 R177 Q189 D193 Y199 E201 I227 M229 W245 Y251 W166 Y168 R177 Q189 D193 Y199 E201 I227 M229 W245 Y251 Q2UNX8 27318092 MSTPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5eo8 A 1.60 BS06 TFU A 6 F220 R230 Q242 R255 P274 L276 W294 F220 R230 Q242 R255 P274 L276 W294 Q2UNX8 27318092 MSTPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5f8e A 2.90 BS01 SAH A 1 Y132 S146 F150 G179 C180 G181 D202 F203 H228 D229 L230 F245 Q251 Y128 S142 F146 G175 C176 G177 D198 F199 H224 D225 L226 F241 Q247 O53532 26772148 METTEEFGNRFVAAIDSAGLAILVSVGHQTGLLDTMAGLPPATSMEIAEAAGLEERYVREWLGGMTTGQIVEYDAGSSTYSLPAHRAGMLTRAAGPDNLAVIAQFVSLLGEVEQKVIRCFREGGGVPYSEYPRFHKLMAEMSGMVFDAALIDVVLPLVDGLPDRLRSGADVADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFERHDLAELDKVGAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASSQLEDNVGVPLSTYLYTTSLMHCMTVSLALDGAGLGTVWGRQLATSMLADAGFTDVTVAEIESDVLNNYYIARKLEHH 5f8e B 2.90 BS01 SAH B 1 M142 S146 G179 C180 G181 D202 F203 H228 D229 L230 F245 D246 Q251 M137 S141 G174 C175 G176 D197 F198 H223 D224 L225 F240 D241 Q246 O53532 26772148 ETTEEFGNRFVAAIDSAGLAILVSVGHQTGLLDTMAGLPPATSMEIAEAAGLEERYVREWLGGMTTGQIVEYDAGSSTYSLPAHRAGMLTRAAGPDNLAVIAQFVSLLGEVEQKVIRCFREGGGVPYSEYPRFHKLMAEMSGMVFDAALIDVVLPLVDGLPDRLRSGADVADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFERHDLAELDKVGAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASSQLEDNVGVPLSTYLYTTSLMHCMTVSLALDGAGLGTVWGRQLATSMLADAGFTDVTVAEIESDVLNNYYIARKLE 5f8f B 1.90 BS01 SFG B 1 Y132 M142 S146 F150 G179 C180 G181 D202 F203 H228 D229 L230 F245 D246 A247 Q251 Y138 M148 S152 F156 G185 C186 G187 D208 F209 H234 D235 L236 F251 D252 A253 Q257 O53532 26772148 SSGLVPRGSHMETTEEFGNRFVAAIDSAGLAILVSVGHQTGLLDTMAGLPPATSMEIAEAAGLEERYVREWLGGMTTGQIVEYDAGSSTYSLPAHRAGMLTRAAGPDNLAVIAQFVSLLGEVEQKVIRCFREGGGVPYSEYPRFHKLMAEMSGMVFDAALIDVVLPLVDGLPDRLRSGADVADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFERHDLAELDKVGAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASSQLEDNVGVPLSTYLYTTSLMHCMTVSLALDGAGLGTVWGRQLATSMLADAGFTDVTVAEIESDVLNNYYIARKLE 5f9b B 2.25 BS01 5VN B 1 G284 C285 R288 S289 I326 Y327 L330 L340 I341 S342 F363 M364 H449 G62 C63 R66 S67 I104 Y105 L108 L118 I119 S120 F140 M141 H226 P37231 27283034 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIY 5fa8 A 1.30 BS01 SAM A 1 V10 P11 T12 D34 G36 C37 G38 R41 I42 E59 I60 R64 G86 N87 F88 F102 V8 P9 T10 D32 G34 C35 G36 R39 I40 E57 I58 R62 G84 N85 F86 F100 C3MWA1 YVPHVPYVPTPEKVVRRMLEIAKVSQDDIVYDLGCGDGRIIITAAKDFNVKKAVGVEINDERIREALANIEKNGVTGRASIVKGNFFEVDISEATVVTMFLLTNVNEMLKPKLEKELKPGTRVVSHEFEIRGWNPKEVIKVEDGNMNHTVYLYVIG 5fa8 A 1.30 BS02 MG A 1 H128 E129 H150 H126 E127 H148 C3MWA1 YVPHVPYVPTPEKVVRRMLEIAKVSQDDIVYDLGCGDGRIIITAAKDFNVKKAVGVEINDERIREALANIEKNGVTGRASIVKGNFFEVDISEATVVTMFLLTNVNEMLKPKLEKELKPGTRVVSHEFEIRGWNPKEVIKVEDGNMNHTVYLYVIG 5fad A 1.87 BS01 SAH A 1 V4 V7 P8 Y9 V10 P11 T12 D34 G36 C37 G38 I42 E59 I60 G86 N87 F88 F102 V3 V6 P7 Y8 V9 P10 T11 D33 G35 C36 G37 I41 E58 I59 G85 N86 F87 F101 C3MWA1 SYVPHVPYVPTPEKVVRRMLEIAKVSQDDIVYDLGCGDGRIIITAAKDFNVKKAVGVEINDERIREALANIEKNGVTGRASIVKGNFFEVDISEATVVTMFLLTNVNEMLKPKLEKELKPGTRVVSHEFEIRGWNPKEVIKVEDGNMNHTVYLYVIGEHK 5fl7 A 3.50 BS01 ATP A 1 Q198 G200 K201 T202 Q203 F383 R388 P389 Q456 Q458 Q150 G152 K153 T154 Q155 F335 R340 P341 Q408 Q410 Q6C326 ANLNETGRVLSVGDGIARVFGLNNIQAEELVEFASGVKGMALNLEAGQVGIVLFGSDRLVKEGETVKRSGSIVDVPVGPALLGRVVDALGNPIDGKGPIETEFRIRAQVKAPGILPRTSVNEPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTQIAIDTILNQKRWNYGQDEKKKLYCVYVAVGQKRSTVAQLVQTLEHHDALKYSIIVAATASEAAPLQYLAPFTGTAMGEWFRDNGKGALIVFDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNEREGGGSLTALPIIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLTRGERLTLLLKQKQASPMSSEEMVPLIYAGVNGYIDNIPVKQVEKFEAEFVSYLHANESDLLKDIAATGELSKENLEKLKSITENFVGS 5fl7 B 3.50 BS01 ATP B 1 Q198 T199 G200 K201 T202 Q203 F383 P389 Q456 K457 Q150 T151 G152 K153 T154 Q155 F335 P341 Q402 K403 Q6C326 ANLNETGRVLSVGDGIARVFGLNNIQAEELVEFASGVKGMALNLEAGQVGIVLFGSDRLVKEGETVKRSGSIVDVPVGPALLGRVVDALGNPIDGKGPIETEFRIRAQVKAPGILPRTSVNEPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTQIAIDTILNQKRWNYGQDEKKKLYCVYVAVGQKRSTVAQLVQTLEHHDALKYSIIVAATASEAAPLQYLAPFTGTAMGEWFRDNGKGALIVFDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNEREGGGSLTALPIIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAADLDASTKQTLTRGERLTLLLKQKQASPMSSEEMVPLIYAGVNGYIDNIPVKQVEKFEAEFVSYLHANESDLLKDIAATGELSKENLEKLKSITENFVGS 5fl7 B 3.50 BS02 ADP F 1 V397 R399 V349 R351 Q6C326 ANLNETGRVLSVGDGIARVFGLNNIQAEELVEFASGVKGMALNLEAGQVGIVLFGSDRLVKEGETVKRSGSIVDVPVGPALLGRVVDALGNPIDGKGPIETEFRIRAQVKAPGILPRTSVNEPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTQIAIDTILNQKRWNYGQDEKKKLYCVYVAVGQKRSTVAQLVQTLEHHDALKYSIIVAATASEAAPLQYLAPFTGTAMGEWFRDNGKGALIVFDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNEREGGGSLTALPIIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAADLDASTKQTLTRGERLTLLLKQKQASPMSSEEMVPLIYAGVNGYIDNIPVKQVEKFEAEFVSYLHANESDLLKDIAATGELSKENLEKLKSITENFVGS 5fl7 C 3.50 BS01 ATP C 1 R197 Q198 T199 G200 K201 T202 Q203 F383 R388 P389 Q456 Q458 R149 Q150 T151 G152 K153 T154 Q155 F335 R340 P341 Q408 Q410 Q6C326 ANLNETGRVLSVGDGIARVFGLNNIQAEELVEFASGVKGMALNLEAGQVGIVLFGSDRLVKEGETVKRSGSIVDVPVGPALLGRVVDALGNPIDGKGPIETEFRIRAQVKAPGILPRTSVNEPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTQIAIDTILNQKRWNYGQDEKKKLYCVYVAVGQKRSTVAQLVQTLEHHDALKYSIIVAATASEAAPLQYLAPFTGTAMGEWFRDNGKGALIVFDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNEREGGGSLTALPIIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLTRGERLTLLLKQKQASPMSSEEMVPLIYAGVNGYIDNIPVKQVEKFEAEFVSYLHANESDLLKDIAATGELSKENLEKLKSITENFVGS 5fl7 C 3.50 BS02 ADP D 1 V397 S398 R399 V349 S350 R351 Q6C326 ANLNETGRVLSVGDGIARVFGLNNIQAEELVEFASGVKGMALNLEAGQVGIVLFGSDRLVKEGETVKRSGSIVDVPVGPALLGRVVDALGNPIDGKGPIETEFRIRAQVKAPGILPRTSVNEPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTQIAIDTILNQKRWNYGQDEKKKLYCVYVAVGQKRSTVAQLVQTLEHHDALKYSIIVAATASEAAPLQYLAPFTGTAMGEWFRDNGKGALIVFDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNEREGGGSLTALPIIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLTRGERLTLLLKQKQASPMSSEEMVPLIYAGVNGYIDNIPVKQVEKFEAEFVSYLHANESDLLKDIAATGELSKENLEKLKSITENFVGS 5fl7 D 3.50 BS01 ADP D 1 G191 G193 K194 T195 V196 Y376 F449 A452 F455 G155 G157 K158 T159 V160 Y340 F413 A416 F419 3.6.3.14 Q6CFT7 GVGSGKIRTVIGAVVDVQFEQDNLPAILNALTIDRGEGNKLVLEVAQHLGENTVRTIAMDGTEGLVRGTSVADTGAPITIPVGRGTLGRIINVCGEPIDERGPIEATKFLPIHADPPTFAEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFCGVGERTREGNDLYREMKETGVINLEGESKVTLVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTQKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDIDVVGQEHYDVASNVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFTVAEVFTGIEGRLVSLKDTVRSFKEILDGKHDALPEAAFYMVGGIEEVVAKAEKLAA 5fl7 D 3.50 BS02 MG D 1 T195 R221 T159 R185 3.6.3.14 Q6CFT7 GVGSGKIRTVIGAVVDVQFEQDNLPAILNALTIDRGEGNKLVLEVAQHLGENTVRTIAMDGTEGLVRGTSVADTGAPITIPVGRGTLGRIINVCGEPIDERGPIEATKFLPIHADPPTFAEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFCGVGERTREGNDLYREMKETGVINLEGESKVTLVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTQKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDIDVVGQEHYDVASNVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFTVAEVFTGIEGRLVSLKDTVRSFKEILDGKHDALPEAAFYMVGGIEEVVAKAEKLAA 5fl7 E 3.50 BS01 ATP B 1 R387 D390 R349 D352 3.6.3.14 Q6CFT7 GSGKIRTVIGAVVDVQFEQDNLPAILNALTIDRGEGNKLVLEVAQHLGENTVRTIAMDGTEGLVRGTSVADTGAPITIPVGRGTLGRIINVCGEPIDERGPIEATKFLPIHADPPTFAEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFCGVGERTREGNDLYREMKETGVINLEGESKVTLVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTQKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDIDVVGQEHYDVASNVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFTVAEVFTGIEGRLVSLKDTVRSFKEILDGKHDALPEAAFYMVGGIEEVVAKAEKLAA 5fl7 F 3.50 BS01 ADP F 1 G191 G193 K194 T195 V196 Y376 F449 F455 G155 G157 K158 T159 V160 Y340 F413 F419 3.6.3.14 Q6CFT7 GVGSGKIRTVIGAVVDVQFEQDNLPAILNALTIDRGEGNKLVLEVAQHLGENTVRTIAMDGTEGLVRGTSVADTGAPITIPVGRGTLGRIINVCGEPIDERGPIEATKFLPIHADPPTFAEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFCGVGERTREGNDLYREMKETGVINLEGESKVTLVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTQKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDIDVVGQEHYDVASNVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFTVAEVFTGIEGRLVSLKDTVRSFKEILDGKHDALPEAAFYMVGGIEEVVAKAEKLAA 5fl7 F 3.50 BS02 MG F 1 T195 E220 T159 E184 3.6.3.14 Q6CFT7 GVGSGKIRTVIGAVVDVQFEQDNLPAILNALTIDRGEGNKLVLEVAQHLGENTVRTIAMDGTEGLVRGTSVADTGAPITIPVGRGTLGRIINVCGEPIDERGPIEATKFLPIHADPPTFAEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFCGVGERTREGNDLYREMKETGVINLEGESKVTLVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTQKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDIDVVGQEHYDVASNVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFTVAEVFTGIEGRLVSLKDTVRSFKEILDGKHDALPEAAFYMVGGIEEVVAKAEKLAA 5fl7 H 3.50 BS01 III I 1 S70 I87 I124 E125 V128 S56 I73 I104 E105 V108 3.6.1.34 Q6C877 LTQSIYNQKEVTQVNIPSTAGELGILANHVPTIQQLKPGVVEVIETNGETKSYFISGGFATVQPDSELSVNSIEAFQAEDKSLTAEAQKNAQSADEAVAAEAEIELEVLEALA 5fvb O 1.93 BS04 PEB O 3 N45 C48 D52 G56 C59 R127 A134 Q135 A138 H139 P144 S145 R148 A149 K152 L153 R154 N45 C48 D52 G56 C59 R127 A134 Q135 A138 H139 P144 S145 R148 A149 K152 L153 R154 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5fvb Q 1.93 BS04 PEB Q 3 C48 D52 A55 G56 C59 E60 R127 I131 A134 Q135 A138 H139 P144 S145 R148 A149 K152 L153 C48 D52 A55 G56 C59 E60 R127 I131 A134 Q135 A138 H139 P144 S145 R148 A149 K152 L153 A0A0E4G455 27068646 MLDAFSRAVVQADASTSVVADMGALKQFIAEGNRRLDAVNAIASNASCMVSDAVAGMICENQGLIQAGGNCYPNRRMAACLRDAEIILRYVTYALLAGDASVLDDRCLNGLKETYAALGVPTTSTVRAVQIMKAQAAAHIKDTPSEARAGGKLRKMGSPVVEDRCASLVAEASSYFDRVISALS 5g56 A 2.64 BS01 CA A 1 D392 D394 V396 G407 D409 D357 D359 V361 G372 D374 A3DHG6 ASPQRGRPRLNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGFNAVHLYAECFDPRYPAPGSKAPGYAVNEIDKIVERTRELGLYLVITIGNGANNGNHNAQWARDFWKFYAPRYAKETHVLYEIHNEPVAWGPPYSSSTANPPGAVDMEIDVYRIIRTYAPETPVLLFSYAVFGGKGGAAEALKDIRAFNKAVFGNENAVWTNEAVAFHGYAGWQETTIAVEELLKAGYPCFMTEYAGGAWGSGMGGLDVELTYELERLGVSWLTFQYIPPTGVSDDVTKPEYFSALVENSGLSWTPDYGNWPAARGVYGNGGLARETATWINNFLTGTTRIEAEDFDWGGNGVSYYDTDSVNVGGQYRPDEGVDIEKTSDTGGGYNVGWISEGEWLEYTIRVRNPGYYNLSLRVAGISGSRVQVSFGNQDKTGVWELPATGGFQTWTTATRQVFLGAGLQKLRINALSGGFNLNWIELSPISTGTIPDGTYKFLNRANGKTLQEVTGNNSIITADYKGITEQHWKIQHIGGGQYRISSAGRGWNWNWWMGFGTVGWWGTGSSTCFIISPTGDGYYRIVLVGDGTNLQISSGDPSKIEGKAFHGGANQQWAILPVSAPAFPTGLSAVLDSSGNTANLTWNAAPGANSYNVKRSTKSGGPYTTIATNITSTNYTDTGVATGTKYYYVVSAVSNGVETLNSAEAILQYPK 5g56 A 2.64 BS02 CA A 2 D392 D409 W424 E429 D357 D374 W389 E394 A3DHG6 ASPQRGRPRLNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGFNAVHLYAECFDPRYPAPGSKAPGYAVNEIDKIVERTRELGLYLVITIGNGANNGNHNAQWARDFWKFYAPRYAKETHVLYEIHNEPVAWGPPYSSSTANPPGAVDMEIDVYRIIRTYAPETPVLLFSYAVFGGKGGAAEALKDIRAFNKAVFGNENAVWTNEAVAFHGYAGWQETTIAVEELLKAGYPCFMTEYAGGAWGSGMGGLDVELTYELERLGVSWLTFQYIPPTGVSDDVTKPEYFSALVENSGLSWTPDYGNWPAARGVYGNGGLARETATWINNFLTGTTRIEAEDFDWGGNGVSYYDTDSVNVGGQYRPDEGVDIEKTSDTGGGYNVGWISEGEWLEYTIRVRNPGYYNLSLRVAGISGSRVQVSFGNQDKTGVWELPATGGFQTWTTATRQVFLGAGLQKLRINALSGGFNLNWIELSPISTGTIPDGTYKFLNRANGKTLQEVTGNNSIITADYKGITEQHWKIQHIGGGQYRISSAGRGWNWNWWMGFGTVGWWGTGSSTCFIISPTGDGYYRIVLVGDGTNLQISSGDPSKIEGKAFHGGANQQWAILPVSAPAFPTGLSAVLDSSGNTANLTWNAAPGANSYNVKRSTKSGGPYTTIATNITSTNYTDTGVATGTKYYYVVSAVSNGVETLNSAEAILQYPK 5g56 A 2.64 BS03 CA A 3 E377 E379 Y420 N509 E342 E344 Y385 N474 A3DHG6 ASPQRGRPRLNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGFNAVHLYAECFDPRYPAPGSKAPGYAVNEIDKIVERTRELGLYLVITIGNGANNGNHNAQWARDFWKFYAPRYAKETHVLYEIHNEPVAWGPPYSSSTANPPGAVDMEIDVYRIIRTYAPETPVLLFSYAVFGGKGGAAEALKDIRAFNKAVFGNENAVWTNEAVAFHGYAGWQETTIAVEELLKAGYPCFMTEYAGGAWGSGMGGLDVELTYELERLGVSWLTFQYIPPTGVSDDVTKPEYFSALVENSGLSWTPDYGNWPAARGVYGNGGLARETATWINNFLTGTTRIEAEDFDWGGNGVSYYDTDSVNVGGQYRPDEGVDIEKTSDTGGGYNVGWISEGEWLEYTIRVRNPGYYNLSLRVAGISGSRVQVSFGNQDKTGVWELPATGGFQTWTTATRQVFLGAGLQKLRINALSGGFNLNWIELSPISTGTIPDGTYKFLNRANGKTLQEVTGNNSIITADYKGITEQHWKIQHIGGGQYRISSAGRGWNWNWWMGFGTVGWWGTGSSTCFIISPTGDGYYRIVLVGDGTNLQISSGDPSKIEGKAFHGGANQQWAILPVSAPAFPTGLSAVLDSSGNTANLTWNAAPGANSYNVKRSTKSGGPYTTIATNITSTNYTDTGVATGTKYYYVVSAVSNGVETLNSAEAILQYPK 5h9p A 2.04 BS01 TD2 A 1 R144 I145 A146 H158 N160 R162 N174 W181 E184 R186 R32 I33 A34 H46 N48 R50 N62 W69 E72 R74 P17931 PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI 5h9q B 1.93 BS01 TD2 B 1 H33 H49 N51 R53 N62 W69 E72 R74 H30 H46 N48 R50 N59 W66 E69 R71 P47929 PHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF 5hee A 1.41 BS01 ZN A 1 H10 H48 D222 H10 H48 D222 Q5JHM2 27303894 MLFGIGLMPHGNPALSPEDKETEKLAGVLKDIGKAFSDADSYVLISPHNVRISDHLGVIMAQHLISWLGFEGVELPGEWETDRGLAEEVYNAWKGAEIPTVDLHFASRSGRYSRWPLTWGELIPLQFLEKKPLVLLTPARRLSRETLIKAGEVLGEVLEGSEKKIALIVSADHGHAHDENGPYGYRKESEEYDRLIMELINESRLEELPEIPDELIEKALPDSYWQMLIMLGAMHRVPVKLVESAYACPTYFGMAGALWVRE 5hee A 1.41 BS02 ZN A 2 E198 E202 E198 E202 Q5JHM2 27303894 MLFGIGLMPHGNPALSPEDKETEKLAGVLKDIGKAFSDADSYVLISPHNVRISDHLGVIMAQHLISWLGFEGVELPGEWETDRGLAEEVYNAWKGAEIPTVDLHFASRSGRYSRWPLTWGELIPLQFLEKKPLVLLTPARRLSRETLIKAGEVLGEVLEGSEKKIALIVSADHGHAHDENGPYGYRKESEEYDRLIMELINESRLEELPEIPDELIEKALPDSYWQMLIMLGAMHRVPVKLVESAYACPTYFGMAGALWVRE 5hvs A 1.75 BS01 65V A 1 P1 M2 K32 P33 Y36 H62 S63 I64 M101 V106 F113 P1 M2 K32 P33 Y36 H62 S63 I64 M101 V106 F113 5.3.2.1,5.3.3.12 P14174 27299179 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 5hxb X 3.60 BS01 85C Z 1 Q534 V536 V570 D571 K572 K573 S574 G575 I626 G627 K628 Q95 V97 V131 D132 K133 K134 S135 G136 I187 G188 K189 P15170 IRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVP 5hxb Z 3.60 BS02 85C Z 1 N351 P352 H353 E377 H378 S379 W380 W386 W400 N294 P295 H296 E320 H321 S322 W323 W329 W343 Q96SW2 NFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEVILCL 5hxb A 3.60 BS01 85C C 1 V570 D571 K572 K573 S574 G575 K628 V132 D133 K134 K135 S136 G137 K190 P15170 PIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVP 5i4v A 2.61 BS01 67S A 1 F271 T272 L274 S278 E281 M312 T316 R319 F329 L330 F340 L345 H435 F54 T55 L57 S61 E64 M95 T99 R102 F112 L113 F123 L128 H218 Q15596 26990539 VQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPASGSASQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHEGSGSGSHKILHRLLQD 5i4v E 2.61 BS01 67S E 1 F268 F271 T272 L274 S278 E281 M312 T316 R319 F329 L330 F340 L345 I353 H435 F45 F48 T49 L51 S55 E58 M89 T93 R96 F106 L107 F117 L122 I130 H212 Q15596 26990539 VQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGSASQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVKILHRLLQD 5ida A 1.10 BS01 BMA A 1 D22 K43 H52 E59 F126 A127 G128 D21 K42 H51 E58 F125 A126 G127 K1QRB6 AEWVSTTGNTIPDNAIRAGYDINKKALFIARAVVSGEMTPGKCGTHLEGAHIPFAGKEHIIQNYEVLVYPINALGFLDWQQASNGDVPGNAIDTASGIYIGRVLYSGSLIPCKIHTGFKVAYMGFAGKEHQSKEYEALYKVI 5ida D 1.10 BS01 BMA D 1 D22 K43 E59 F126 A127 G128 D21 K42 E58 F125 A126 G127 K1QRB6 AEWVSTTGNTIPDNAIRAGYDINKKALFIARAVVSGEMTPGKCGTHLEGAHIPFAGKEHIIQNYEVLVYPINALGFLDWQQASNGDVPGNAIDTASGIYIGRVLYSGSLIPCKIHTGFKVAYMGFAGKEHQSKEYEALYKVI 5ih2 A 1.80 BS01 III M 1 F141 D142 D147 E149 D150 E166 Q168 W169 P183 P185 Y186 F8 D9 D14 E16 D17 E33 Q35 W36 P50 P52 Y53 Q64010 27332121 AEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYR 5ii1 A 2.02 BS01 6BL A 1 I683 F684 L687 L693 Y696 M704 D705 M731 A735 Y738 N739 I745 I32 F33 L36 L42 Y45 M53 D54 M80 A84 Y87 N88 I94 Q86U86 SKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDL 5ii2 B 2.10 BS01 LU2 B 1 I683 F684 L687 P688 Y696 M704 D705 M731 A735 N739 I745 I32 F33 L36 P37 Y45 M53 D54 M80 A84 N88 I94 Q86U86 SKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLE 5ikw A 2.41 BS01 6BU A 1 L57 A58 G60 S63 V65 A77 M130 E131 Y132 C133 R134 G136 Q137 E184 N185 L187 C197 L16 A17 G19 S22 V24 A36 M89 E90 Y91 C92 R93 G95 Q96 E143 N144 L146 C156 2.7.11.1 Q9NSY1 RVFAVGRHQVTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALP 5iqs A 2.00 BS01 FE2 A 1 H164 H259 H154 H249 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqs A 2.00 BS02 AKG A 1 R153 H164 S189 F191 H259 V261 R270 T272 F276 R143 H154 S179 F181 H249 V251 R260 T262 F266 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqs B 2.00 BS02 AKG B 1 R153 H164 S189 F191 H259 V261 R270 T272 R144 H155 S180 F182 H250 V252 R261 T263 A0A067YX61 PALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqt A 2.40 BS02 AKG A 1 R153 H164 S189 F191 F252 H259 V261 R270 T272 R143 H154 S179 F181 F242 H249 V251 R260 T262 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqt A 2.40 BS03 6CU A 1 F77 V81 A82 I84 V90 R153 H164 F276 F67 V71 A72 I74 V80 R143 H154 F266 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqt B 2.40 BS03 6CU B 1 N74 F77 V81 A82 I84 V90 R153 H164 F169 M221 M225 F276 N64 F67 V71 A72 I74 V80 R143 H154 F159 M211 M215 F266 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqt C 2.40 BS02 AKG C 1 R153 H164 S189 F191 F252 H259 R270 T272 R143 H154 S179 F181 F239 H246 R257 T259 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqu A 2.51 BS01 FE2 A 1 H164 D166 H259 H146 D148 H236 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVDNDAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqu A 2.51 BS02 AKG A 1 R153 H164 D166 S189 F191 F252 H259 V261 R270 T272 R135 H146 D148 S166 F168 F229 H236 V238 R247 T249 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVDNDAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqu A 2.51 BS03 6CU A 1 N74 F77 V81 A82 A88 H164 N64 F67 V71 A72 A78 H146 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVDNDAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqv A 2.40 BS01 FE2 A 1 H164 S189 H259 H154 S179 H246 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqv A 2.40 BS03 6CU A 1 F77 V81 A82 I84 A88 V90 R153 I161 H164 F169 M221 M225 F276 F67 V71 A72 I74 A78 V80 R143 I151 H154 F159 M208 M212 F263 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqv A 2.40 BS04 NO A 1 H164 F276 H154 F263 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEYAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqv B 2.40 BS03 6CU B 1 N74 V81 A82 I84 A88 V90 R153 I161 H164 F169 M225 F276 N64 V71 A72 I74 A78 V80 R143 I151 H154 F159 M211 F262 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEAQMQEYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqv C 2.40 BS02 AKG C 1 R153 I161 H164 S189 F191 H259 V261 R270 T272 R143 I151 H154 S179 F181 H243 V245 R254 T256 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5iqv C 2.40 BS03 6CU C 1 F77 V81 A82 I84 V90 R153 H164 F169 F276 F67 V71 A72 I74 V80 R143 H154 F159 F260 A0A067YX61 ALHFLDINATEVKKYPTAIQDIIINRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDLKDYFASSAIFRQACRTMFQGSPDFEEQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDFLLMPAANHLKTLLDLSDQLSYFIPLTVPEAGGELVVYSLEWNPQEASKYMDDVEFKIKSNQSQSVAYAPGPGDMLLFNGGRYYHRVSEVIGNSPRRTIGGFLAFSKQRDKIYYWS 5irl A 3.09 BS01 ADP A 1 Y232 T233 G282 S283 G284 K285 S286 T287 Y435 P466 W470 H583 Y31 T32 G62 S63 G64 K65 S66 T67 Y215 P246 W250 H342 G1T469 27283905 EAAACKKYMSKLRTIVAAQSRFLNLCLEDIYTENTLEVRTAALGLEELFSDADTVLVVGEAGSGKSTLLQQVHLLWATGQDFQEFLFVFPFSCRQLQCVARPLSVMTLLFEHCCWPDVGQQDVFQFLLDHPDRILLTFDGFDEFKFKFTDHERHCSPTDPTSVQTLLFNLLQGNLLKNARKVLTSRPDAVSAFLRKYVRTEFNLKGFSEEGIELYLRKCHREPGVADRLIHLLQTTSALHGLCHLPVFSWMVSKCHQELLLQDGGSPKTTTDMYLLILQHFLRHASLLQGRLPTLLRLGQLALWGLGMCCYVFSAQQLQAAQVDPDDISLGFLVQAPLEFLHITFQCFLAAFYLVLSTDVPTASLRYLFNCSTVAALLQKTEPHNLQITAAFLAGLLSREHRDLLAACQASERSLLRRRACARWCLARSLHKHFRSIPAMPGFLWLIRSLYEMQEERLAQEAVRGLNVEHLKLTFCGVGPAECAALAFVLRHLRRPVALQLDHNSVGDIGVEQLLPCLGACKALYLRDNNISDRGICKLIEHALHCEQLQKLALFNNKLTDGCAHSVAQLLACKQNFLALRLGNNHITAEGAQVLAEGLRDNSSLQFLGFWGNKVGDKGAQALAEALSDHQSLKWLSLVGNNIGSVGAQALASMLEKNVALEELCLAANHLQDAGVCSLAEGLKRNSSLKVLKLSNNCITFVGAEALLQALASNDTILEVWLRGNPFSPEEMEALSHRDSRLLL 5irm A 3.31 BS01 ADP A 1 T219 Y232 T233 G282 G284 K285 S286 T287 F427 Y435 P466 V467 H583 T27 Y34 T35 G73 G75 K76 S77 T78 F218 Y226 P257 V258 H365 G1T469 27283905 EFEAAACKKYMSKLRTIVAAQSRFLSTLCLEDIYTENTLEVRTPAALGLEELFSPNGHLNEDADTVLVVGEAGSGKSTLLQQVHLLWATGQDFQEFLFVFPFSCRQLQCVARPLSVMTLLFEHCCWPDVGQQDVFQFLLDHPDRILLTFDGFDEFKFKFTDHERHCSPTDPTSVQTLLFNLLQGNLLKNARKVLTSRPDAVSAFLRKYVRTEFNLKGFSEEGIELYLRKCHREPGVADRLIHLLQTTSALHGLCHLPVFSWMVSKCHQELLLQDGGSPKTTTDMYLLILQHFLRHALGPSLLQGRLPTLLRLGQLALWGLGMCCYVFSAQQLQAAQVDPDDISLGFLVQAQGVVPGSTAPLEFLHITFQCFLAAFYLVLSTDVPTASLRYLFNCESTVAALLQKTEPHNLQITAAFLAGLLSREHRDLLAACQASERSLLRRRACARWCLARSLHKHFRSIAMPGFLWLIRSLYEMQEERLAQEAVRGLNVEHLKLTFCGVGPAECAALAFVLRHLRRPVALQLDHNSVGDIGVEQLLPCLGACKALYLRDNNISDRGICKLIEHALHCEQLQKLALFNNKLTDGCAHSVAQLLACKQNFLALRLGNNHITAEGAQVLAEGLRDNSSLQFLGFWGNKVGDKGAQALAEALSDHQSLKWLSLVGNNIGSVGAQALASMLEKNVALEELCLEENHLQDAGVCSLAEGLKRNSSLKVLKLSNNCITFVGAEALLQALASNDTILEVWLRGNPFSPEEMEALSHRDSRLLL 5irm C 3.31 BS01 ADP C 1 Y232 T233 G282 S283 G284 K285 S286 T287 F427 Y435 P466 H583 Y34 T35 G77 S78 G79 K80 S81 T82 F222 Y230 P261 H368 G1T469 27283905 EFEAAACKKYMSKLRTIVAAQSRFLENLCLEDIYTENTLEVRTEVGSPAALGLEELFSPNGHLNEDADTVLVVGEAGSGKSTLLQQVHLLWATGQDFQEFLFVFPFSCRQLQCVARPLSVMTLLFEHCCWPDVGQQDVFQFLLDHPDRILLTFDGFDEFKFKFTDHERHCSPTDPTSVQTLLFNLLQGNLLKNARKVLTSRPDAVSAFLRKYVRTEFNLKGFSEEGIELYLRKCHREPGVADRLIHLLQTTSALHGLCHLPVFSWMVSKCHQELLLQDGGSPKTTTDMYLLILQHFLRHAGPSLLQGRLPTLLRLGQLALWGLGMCCYVFSAQQLQAAQVDPDDISLGFLVQAQGVVPGSTAPLEFLHITFQCFLAAFYLVLSTDVPTASLRYLFNCESTVAALLQKTEPHNLQITAAFLAGLLSREHRDLLAACQASERSLLRRRACARWCLARSLHKHFRSIAMPGFLWLIRSLYEMQEERLAQEAVRGLNVEHLKLTFCGVGPAECAALAFVLRHLRRPVALQLDHNSVGDIGVEQLLPCLGACKALYLRDNNISDRGICKLIEHALHCEQLQKLALFNNKLTDGCAHSVAQLLACKQNFLALRLGNNHITAEGAQVLAEGLRDNSSLQFLGFWGNKVGDKGAQALAEALSDHQSLKWLSLVGNNIGSVGAQALASMLEKNVALEELCLEENHLQDAGVCSLAEGLKRNSSLKVLKLSNNCITFVGAEALLQALASNDTILEVWLRGNPFSPEEMEALSHRDSRLLL 5irn A 2.34 BS01 ADP A 1 I231 Y232 T233 G282 S283 G284 K285 S286 T287 F427 Y435 P466 V467 W470 H583 I30 Y31 T32 G63 S64 G65 K66 S67 T68 F208 Y216 P247 V248 W251 H343 G1T469 27283905 EAAACKKYMSKLRTIVAAQSRFLNLCLEDIYTENTLEVRTAALGLEELFSEDADTVLVVGEAGSGKSTLLQQVHLLWATGQDFQEFLFVFPFSCRQLQCVARPLSVMTLLFEHCCWPDVGQQDVFQFLLDHPDRILLTFDGFDEFKFKFTDHERHCSPTDPTSVQTLLFNLLQGNLLKNARKVLTSRPDAVSAFLRKYVRTEFNLKGFSEEGIELYLRKCHREPGVADRLIHLLQTTSALHGLCHLPVFSWMVSKCHQELLLQDGGSPKTTTDMYLLILQHFLRHASLLQGRLPTLLRLGQLALWGLGMCCYVFSAQQLQAAQVDPDDISLGFLVQAPLEFLHITFQCFLAAFYLVLSTDVPTASLRYLFNCESTVAALLQKTEPHNLQITAAFLAGLLSREHRDLLAACQASERSLLRRRACARWCLARSLHKHFRSIHAMPGFLWLIRSLYEMQEERLAQEAVRGLNVEHLKLTFCGVGPAECAALAFVLRHLRRPVALQLDHNSVGDIGVEQLLPCLGACKALYLRDNNISDRGICKLIEHALHCEQLQKLALFNNKLTDGCAHSVAQLLACKQNFLALRLGNNHITAEGAQVLAEGLRDNSSLQFLGFWGNKVGDKGAQALAEALSDHQSLKWLSLVGNNIGSVGAQALASMLEKNVALEELCLEENHLQDAGVCSLAEGLKRNSSLKVLKLSNNCITFVGAEALLQALASNDTILEVWLRGNPFSPEEMEALSHRDSRLLL 5isx A 2.34 BS01 PNS A 1 S573 I574 Q646 H753 G758 I866 N867 G893 H894 T913 K945 N975 Y976 L977 S31 I32 Q104 H211 G216 I324 N325 G351 H352 T371 K403 N433 Y434 L435 5.1.1.11 P0C062 27294598 IEETLVTIWQDVLGIEKIGIKDNFYALGGDSIKAIQVAARLHSYQLKLETKDLLKYPTIDQLVHYIKDSKRRSEQGIVEGEIGLTPIQHWFFEQQFTNMHHWNQSYMLYRPNGFDKEILLRVFNKIVEHHDALRMIYKHHNGKIVQINRGLEGTLFDFYTFDLTANDNEQQVICEESARLQNSINLEVGPLVKIALFHTQNGDHLFMAIHHLVVDGISWRILFEDLATAYEQAMHQQTIALPEKTDSFKDWSIELEKYANSELFLEEAEYWHHLNYYTDNVQIKKDYVTMNNKQKNIRYVGMELTIEETEKLLKNVNKAYRTEINDILLTALGFALKEWADIDKIVINLEGHGREEILEQMNIARTVGWFTSQYPVVLDMQKSDDLSYQIKLMKENLRRIPNKGIGYEIFKYLTTEYLRPVLPFTLKPEINFNYLGQFDTDVKTELFTRSPYSMGNSLGPDGKNNLGPEGESYFVLNINGFIEEGKLHITFSYNEQQYKEDTIQQLSRSYKQHLLAIIEHCVQKEDTEL 5isx B 2.34 BS01 PNS B 1 S573 I574 Q646 H753 I866 N867 E892 G893 H894 W911 T913 K945 N975 Y976 L977 S31 I32 Q104 H211 I324 N325 E350 G351 H352 W369 T371 K403 N433 Y434 L435 5.1.1.11 P0C062 27294598 IEETLVTIWQDVLGIEKIGIKDNFYALGGDSIKAIQVAARLHSYQLKLETKDLLKYPTIDQLVHYIKDSKRRSEQGIVEGEIGLTPIQHWFFEQQFTNMHHWNQSYMLYRPNGFDKEILLRVFNKIVEHHDALRMIYKHHNGKIVQINRGLEGTLFDFYTFDLTANDNEQQVICEESARLQNSINLEVGPLVKIALFHTQNGDHLFMAIHHLVVDGISWRILFEDLATAYEQAMHQQTIALPEKTDSFKDWSIELEKYANSELFLEEAEYWHHLNYYTDNVQIKKDYVTMNNKQKNIRYVGMELTIEETEKLLKNVNKAYRTEINDILLTALGFALKEWADIDKIVINLEGHGREEILEQMNIARTVGWFTSQYPVVLDMQKSDDLSYQIKLMKENLRRIPNKGIGYEIFKYLTTEYLRPVLPFTLKPEINFNYLGQFDTDVKTELFTRSPYSMGNSLGPDGKNNLGPEGESYFVLNINGFIEEGKLHITFSYNEQQYKEDTIQQLSRSYKQHLLAIIEHCVQKEDTEL 5iu4 A 1.72 BS01 ZMA A 1 L85 F168 E169 M177 W246 L249 H250 N253 H264 M270 I274 L87 F170 E171 M179 W329 L332 H333 N336 H347 M353 I357 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iu4 A 1.72 BS02 CLR A 1 H75 G76 F79 F133 M140 H77 G78 F81 F135 M142 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iu4 A 1.72 BS03 CLR A 2 F62 A72 A73 G76 F79 I80 F64 A74 A75 G78 F81 I82 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iu4 A 1.72 BS04 CLR A 3 L244 L247 P248 I252 F255 C262 S263 L269 L327 L330 P331 I335 F338 C345 S346 L352 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iu4 A 1.72 BS05 CLR A 4 L187 C254 F255 F258 C259 L189 C337 F338 F341 C342 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iu7 A 1.90 BS01 6DY A 1 L85 F168 E169 M177 W246 L249 H250 N253 H264 A265 L267 M270 I274 L89 F172 E173 M181 W331 L334 H335 N338 H349 A350 L352 M355 I359 P29274 27312113 DDGAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRSHV 5iu7 A 1.90 BS02 CLR A 1 H75 G76 H79 G80 P29274 27312113 DDGAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRSHV 5iu8 A 2.00 BS02 CLR A 1 A72 A73 G76 F79 I80 A74 A75 G78 F81 I82 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iu8 A 2.00 BS03 CLR A 2 L244 L247 P248 C262 S263 L326 L329 P330 C344 S345 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iu8 A 2.00 BS04 CLR A 3 I251 C254 F255 F258 C259 I333 C336 F337 F340 C341 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iua A 2.20 BS04 CLR A 3 L244 L247 P248 F255 C262 S263 L326 L329 P330 F337 C344 S345 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRSH 5iua A 2.20 BS05 CLR A 4 L187 I251 C254 F255 F258 C259 L189 I333 C336 F337 F340 C341 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRSH 5iub A 2.10 BS01 6DV A 1 L85 F168 E169 M177 W246 L249 H250 N253 H264 A265 P266 L267 M270 Y271 I274 L87 F170 E171 M179 W329 L332 H333 N336 H347 A348 P349 L350 M353 Y354 I357 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iub A 2.10 BS03 CLR A 2 L244 L247 P248 I252 F255 S263 L269 L327 L330 P331 I335 F338 S346 L352 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5iub A 2.10 BS04 CLR A 3 L187 L247 I251 C254 F255 F258 C259 L189 L330 I334 C337 F338 F341 C342 P29274 27312113 GAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS 5ize A 1.70 BS01 MN3 A 1 H36 D97 E110 V111 H37 D98 E111 V112 2.7.7.48 P23456 27304209 GMDKYREIHNKLKEFSPGTLTAVECIDYLDRLYAVRHDIVDQMIKHDWSDNKDSEEAIGKVLLFAGVPSNIITALEKKIIPNHPTGKSLKAFFKMTPDNYKISGTTIEFVEVTVTADVDKGIREKKLKYEAGLTYIEQELHKFFLKGEIPQPYKITFNVVAVRTDGSNITTQWPSRRNDG 5ize A 1.70 BS02 MN3 A 2 E54 D97 E55 D98 2.7.7.48 P23456 27304209 GMDKYREIHNKLKEFSPGTLTAVECIDYLDRLYAVRHDIVDQMIKHDWSDNKDSEEAIGKVLLFAGVPSNIITALEKKIIPNHPTGKSLKAFFKMTPDNYKISGTTIEFVEVTVTADVDKGIREKKLKYEAGLTYIEQELHKFFLKGEIPQPYKITFNVVAVRTDGSNITTQWPSRRNDG 5ize A 1.70 BS03 MN3 A 3 H8 S15 G17 H9 S16 G18 2.7.7.48 P23456 27304209 GMDKYREIHNKLKEFSPGTLTAVECIDYLDRLYAVRHDIVDQMIKHDWSDNKDSEEAIGKVLLFAGVPSNIITALEKKIIPNHPTGKSLKAFFKMTPDNYKISGTTIEFVEVTVTADVDKGIREKKLKYEAGLTYIEQELHKFFLKGEIPQPYKITFNVVAVRTDGSNITTQWPSRRNDG 5j1n A 1.09 BS01 MN3 A 1 D89 E102 K122 D90 E103 K123 2.7.7.48 Q6GWS6 27304209 GMEEDIACVKDLVSKYLADNERLSRQKLAFLVQTEPRMLLMEGLKLLSLCIEIDSCNANGCEHNSEDKSVERILHDHGILTPSLCFVVPDGYKLTGNVLILLECFVRSSPANFEQKYIEDFKKLEQLKEDLKTVNISLIPLIDGRTSFYNEQIPDWVNDKLRDTLFSLLRY 5j1p A 2.36 BS01 MN3 A 1 E51 D89 C103 E52 D88 C102 2.7.7.48 Q6GWS6 27304209 GMEEDIACVKDLVSKYLADNERLSRQKLAFLVQTEPRMLLMEGLKLLSLCIEIDSCNANGCEHNSEDKSVERILHDHGILTLCFVVPDGYKLTGNVLILLECFVRSSPANFEQKYIEDFKKLEQLKEDLKTVNISLIPLIDGRTSFYNEQIPDWVNDKLRDTLFSLLRY 5j1p A 2.36 BS02 MN3 A 2 D89 E102 C103 D88 E101 C102 2.7.7.48 Q6GWS6 27304209 GMEEDIACVKDLVSKYLADNERLSRQKLAFLVQTEPRMLLMEGLKLLSLCIEIDSCNANGCEHNSEDKSVERILHDHGILTLCFVVPDGYKLTGNVLILLECFVRSSPANFEQKYIEDFKKLEQLKEDLKTVNISLIPLIDGRTSFYNEQIPDWVNDKLRDTLFSLLRY 5j1p A 2.36 BS03 MN3 A 3 H76 L93 H77 L92 2.7.7.48 Q6GWS6 27304209 GMEEDIACVKDLVSKYLADNERLSRQKLAFLVQTEPRMLLMEGLKLLSLCIEIDSCNANGCEHNSEDKSVERILHDHGILTLCFVVPDGYKLTGNVLILLECFVRSSPANFEQKYIEDFKKLEQLKEDLKTVNISLIPLIDGRTSFYNEQIPDWVNDKLRDTLFSLLRY 5j8z A 1.70 BS03 6KE A 1 Q92 H94 H96 H119 V121 F131 G132 L198 T199 T200 P202 W209 Q93 H95 H97 H120 V122 F131 G132 L198 T199 T200 P202 W209 4.2.1.1 P00918 27316543 GMSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5jge D 1.91 BS01 III F 1 H158 M159 L160 M164 L167 E171 L174 N175 L177 E178 Q181 H3 M4 L5 M9 L12 E16 L19 N20 L22 E23 Q26 P35193 27320913 GPHMLDNFMKQLLKLEESLNKLELEQKVTN 5jge E 1.91 BS01 III F 1 M159 F163 Q166 L170 S173 M4 F8 Q11 L15 S18 P35193 27320913 GPHMLDNFMKQLLKLEESLNKLELEQKVTN 5jgf A 1.83 BS01 ZN A 1 H132 D303 D385 H86 D252 D334 3.4.11.22 P14904 27320913 HNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEF 5jgf A 1.83 BS02 ZN A 2 D303 E340 H479 D252 E289 H428 3.4.11.22 P14904 27320913 HNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEF 5jh7 B 2.25 BS02 6K9 B 1 Q11 P175 K176 V177 S178 D179 T180 Y210 P222 T223 Y224 L227 Q11 P173 K174 V175 S176 D177 T178 Y208 P220 T221 Y222 L225 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5jh7 B 2.25 BS03 03S B 1 Q11 E71 N101 Q11 E69 N99 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5jh7 C 2.25 BS01 6K9 B 1 A247 L248 V250 N329 F351 K352 V353 A247 L248 V250 N329 F351 K352 V353 P81947 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5jh7 D 2.25 BS02 6K9 D 1 Q11 P175 V177 S178 D179 T180 P222 T223 Y224 L227 Q11 P173 V175 S176 D177 T178 P220 T221 Y222 L225 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5jh7 F 2.25 BS01 ACP F 1 K74 I148 K150 Q183 K184 Y185 L186 K198 R222 H239 T241 N242 D318 E331 N333 K74 I122 K124 Q154 K155 Y156 L157 K169 R193 H210 T212 N213 D289 E302 N304 E1BQ43 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPDEREVFLAAYNRRREGNVWIAKSSAGEGILISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH 5jj4 C 2.81 BS01 ZN C 1 H1056 C1087 C1090 H416 C447 C450 3.5.4.38 Q9GZX7 27258794 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAALMDPHIFTSNFNNGIGRHKTYLCYEVERLDSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILL 5jj4 C 2.81 BS02 CA C 1 Q325 G327 Q325 G327 3.5.4.38 Q9GZX7 27258794 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAALMDPHIFTSNFNNGIGRHKTYLCYEVERLDSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILL 5jj4 C 2.81 BS03 MTT C 1 D14 K15 K42 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 W230 M330 W340 Y341 R344 D14 K15 K42 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 W230 M330 W340 Y341 R344 3.5.4.38 Q9GZX7 27258794 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAALMDPHIFTSNFNNGIGRHKTYLCYEVERLDSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILL 5jj4 B 2.81 BS02 CA B 1 Q325 G327 E328 Q325 G327 E328 3.5.4.38 Q9GZX7 27258794 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAALMDPHIFTSNFNNGIGRHKTYLCYEVERLDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLP 5jj4 B 2.81 BS03 MTT B 1 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 W340 Y341 R344 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 W340 Y341 R344 3.5.4.38 Q9GZX7 27258794 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAALMDPHIFTSNFNNGIGRHKTYLCYEVERLDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLP 5jlj A 2.50 BS01 GNP A 1 G19 G20 T21 G22 K23 T24 T25 E36 K37 K38 Y39 A41 T42 A67 G68 N122 K123 D125 I126 S150 A151 K152 G11 G12 T13 G14 K15 T16 T17 E28 K29 K30 Y31 A33 T34 A59 G60 N114 K115 D117 I118 S142 A143 K144 P62826 27323910 VQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVAAQYEHDLEVAQTTALPDEDDDL 5jlj C 2.50 BS01 6L8 C 1 L536 C539 V540 K548 I555 M556 F572 T575 V576 K579 L580 F583 L500 C503 V504 K512 I519 M520 F536 T539 V540 K543 L544 F547 P30822 27323910 SMEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEPLKKHIYEEICSQLRLVIIENMVRPEEVLVVENDEGEIVREFVKESDTIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLDLCVKKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQCKDLVVFKGTLRDFLVQIKEVGGDPTDYLFAE 5jmu A 1.54 BS01 ZN A 1 D298 H346 H350 D22 H70 H74 C4ZEZ9 DPAATADTVNPGNKIIYLTFDDGPGKYTQGLLDVLDKYNVKATFFVTNTHPDYQNMIAEEAKRGHTVAIHSASHKYNQIYTSEQAFFDDLEQMNSIIKAQTGNDASIIRFPGGSSNTVSKDYCPGIMTQLVNDVTARGLLYCDWNVSSGDANPKPISTEQVVQNVISGVQSHNVSVVLQHDIKEFSVNAVEQIIQWGQANGYTFLPLTTSSPMSHHRVNN 5jph A 1.46 BS01 COA A 1 F22 I28 S32 D35 Y37 R57 R59 E69 R70 V71 M104 N105 E128 E129 F23 I29 S33 D36 Y38 R58 R60 E70 R71 V72 M105 N106 E129 E130 2.3.1.- Q5HH30 AMFSKVNNQKMLEDCFYIRKKVFVEEQGIPEESEIDEYESESIHLIGYDNGQPVATARIRPINETTVKIERVAVMKSHRGQGMGRMLMQAVESLAKDEGFYVATMNAQCHAIPFYESLNFKMRGNIFLEEGIEHIEMTKKLT 5jph A 1.46 BS02 COA A 2 V21 Q26 V71 A72 V73 R78 G79 Q80 G81 G83 R84 A106 Q107 H109 P112 F113 Y114 V22 Q27 V72 A73 V74 R79 G80 Q81 G82 G84 R85 A107 Q108 H110 P113 F114 Y115 2.3.1.- Q5HH30 AMFSKVNNQKMLEDCFYIRKKVFVEEQGIPEESEIDEYESESIHLIGYDNGQPVATARIRPINETTVKIERVAVMKSHRGQGMGRMLMQAVESLAKDEGFYVATMNAQCHAIPFYESLNFKMRGNIFLEEGIEHIEMTKKLT 5jq7 A 2.69 BS01 T0R B 1 R64 V66 E100 A101 L184 L186 R35 V37 E71 A72 L155 L157 Q05320 GRSIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTEWAFWETSEELSFTVVGGGGGGG 5jq7 B 2.69 BS01 T0R B 1 L515 Y517 T519 T520 D522 M548 L558 L14 Y16 T18 T19 D21 M47 L57 Q05320 EAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKIDQIIHDFVD 5jqb A 2.68 BS01 IBP B 1 R64 A101 L184 L186 R33 A70 L153 L155 Q05320 SIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTEWAFWETLSFTVVGGGGGGG 5jqb B 2.68 BS01 IBP B 1 Y517 M548 Y16 M47 Q05320 EAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKIDQIIHDFVD 5k14 A 2.40 BS01 IB1 A 1 P95 L100 K101 K103 V106 V179 Y181 Y188 F227 W229 L234 H235 P236 Y318 P92 L97 K98 K100 V103 V176 Y178 Y185 F220 W222 L227 H228 P229 Y311 P04585 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIG 5kbj A 3.09 BS01 NUC R 1 K78 E80 K81 K84 R99 G101 K75 E77 K78 K81 R96 G98 D2JDC3 24927575 QYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRDRLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNKPNILYLMKPIVTERDIYKIEKEENDVEPY 5kbj A 3.09 BS02 NUC W 1 N68 K79 T83 K86 K87 Q97 R99 L102 N106 N65 K76 T80 K83 K84 Q94 R96 L99 N103 D2JDC3 24927575 QYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRDRLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNKPNILYLMKPIVTERDIYKIEKEENDVEPY 5kbj B 3.09 BS01 NUC R 1 S67 N68 K79 K86 Q97 R99 L102 N103 P105 N106 S64 N65 K76 K83 Q94 R96 L99 N100 P102 N103 D2JDC3 24927575 QYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRDRLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNKPNILYLMKPIVTERDIYKIEKEENDVEPY 5kbj B 3.09 BS02 NUC W 1 K78 K79 E80 K81 R99 G101 L102 K75 K76 E77 K78 R96 G98 L99 D2JDC3 24927575 QYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRDRLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNKPNILYLMKPIVTERDIYKIEKEENDVEPY 5kbw A 2.61 BS01 RBF A 1 F33 L34 K35 D73 G76 I77 M79 L83 A119 N123 I126 F148 N149 K152 F32 L33 K34 D72 G75 I76 M78 L82 A118 N122 I125 F147 N148 K151 Q9X1G6 27312125 SSIKKISFVGIFSALATLVMFLEFPIFPQASFLKYDPSEIPALIVSFLLGPGVGMFVVLVKDILFFLMKSGDPVGIAMNAVLGMSFVGIAGLIYHRNKSRATAIKGMIVATLFATAFALGLNALIVPLYFEAPFELYLKFFPFILAFNLVKFGIDSVVTFFVYKKVSSIL 5kbw B 2.61 BS01 RBF B 1 E24 F33 L34 K35 G76 L83 A119 N123 V127 Y130 F148 N149 K152 E23 F32 L33 K34 G75 L82 A118 N122 V126 Y129 F147 N148 K151 Q9X1G6 27312125 SSIKKISFVGIFSALATLVMFLEFPIFPQASFLKYDPSEIPALIVSFLLGPGVGMFVVLVKDILFFLMKSGDPVGIAMNAVLGMSFVGIAGLIYHRNKSRATAIKGMIVATLFATAFALGLNALIVPLYFEAPFELYLKFFPFILAFNLVKFGIDSVVTFFVYKKVSSILK 5kc0 A 3.20 BS01 RBF A 1 F33 L34 K35 K70 D73 G76 I77 L83 A119 N123 I145 F148 N149 K152 F153 F32 L33 K34 K69 D72 G75 I76 L82 A118 N122 I144 F147 N148 K151 F152 Q9X1G6 27312125 SSIKKISFVGIFSALATLVMFLEFPIFPQASFLKYDPSEIPALIVSFLLGPGVGMFVVLVKDILFFLMKSGDPVGIAMNAVLGMSFVGIAGLIYHRNKSRATAIKGMIVATLFATAFALGLNALIVPLYFEAPFELYLKFFPFILAFNLVKFGIDSVVTFFVYKKV 5kc4 A 3.40 BS01 RBF A 1 E24 L34 K35 K70 D73 G76 M79 N80 L83 A119 N123 I145 F148 N149 K152 F153 E23 L33 K34 K69 D72 G75 M78 N79 L82 A118 N122 I144 F147 N148 K151 F152 Q9X1G6 27312125 SSIKKISFVGIFSALATLVMFLEFPIFPQASFLKYDPSEIPALIVSFLLGPGVGMFVVLVKDILFFLMKSGDPVGIAMNAVLGMSFVGIAGLIYHRNKSRATAIKGMIVATLFATAFALGLNALIVPLYFEAPFELYLKFFPFILAFNLVKFGIDSVVTFFVYKKV 5kc4 E 3.40 BS01 RBF E 1 E24 F33 L34 K35 G76 M79 N80 L83 A119 N123 F148 N149 E23 F32 L33 K34 G72 M75 N76 L79 A115 N119 F144 N145 Q9X1G6 27312125 SSIKKISFVGIFSALATLVMFLEFPIFPQASFLKYDPSEIPALIVSFLLGPGVGMFVVLVKDILFFLMDPVGIAMNAVLGMSFVGIAGLIYHRNKSRATAIKGMIVATLFATAFALGLNALIVPLYFEAPFELYLKFFPFILAFNLVKFGIDSVVTFFVYKKV 5kcp A 1.10 BS03 NAJ A 1 C46 R47 T48 H51 C174 T178 G199 G201 G202 V203 D223 I224 K228 V268 I269 R271 V292 G293 V294 A317 I318 F319 R369 C46 R47 T48 H51 C174 T178 G199 G201 G202 V203 D223 I224 K228 V268 I269 R271 V292 G293 V294 A317 I318 F319 R369 1.1.1.1 P00327 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRTDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 5kcp A 1.10 BS04 PFB A 1 C46 T48 L57 H67 F93 L116 F140 L141 C174 V294 I318 C46 T48 L57 H67 F93 L116 F140 L141 C174 V294 I318 1.1.1.1 P00327 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRTDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 5kcp A 1.10 BS05 PFB A 2 T122 G126 S128 P136 I137 H138 T122 G126 S128 P136 I137 H138 1.1.1.1 P00327 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRTDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 5kcp B 1.10 BS05 PFB B 2 P62 T122 S128 P136 I137 H138 P62 T122 S128 P136 I137 H138 1.1.1.1 P00327 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRTDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 5kcv A 2.70 BS01 6S1 A 1 N53 N54 Q79 W80 T82 L210 T211 L264 V270 Y272 R273 D274 I290 D292 N40 N41 Q66 W67 T69 L141 T142 L195 V201 Y203 R204 D205 I221 D223 2.7.11.1 P31749 27305487 IVKEGWLHKRGEYITWRPRYFLLKNDGTFIGYKERPAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYF 5kcz A 1.14 BS04 ETF A 1 C46 T48 H67 F93 C174 V294 C46 T48 H67 F93 C174 V294 1.1.1.1 P00327 STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRTDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLLRSGESIRTILTF 5kfg A 1.55 BS01 NUC T 1 Q38 Y39 W42 S62 W64 K86 L89 R93 K311 P316 K317 T318 G320 C321 S322 K323 N324 P326 G327 T329 R351 Q41 Y42 W45 S65 W67 K89 L92 R96 K309 P314 K315 T316 G318 C319 S320 K321 N322 P324 G325 T327 R349 2.7.7.7 Q9Y253 27284197 GPHMATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSAS 5kfg A 1.55 BS02 NUC P 1 S113 D115 E116 K224 S257 L258 G259 G260 K261 L262 R377 L381 R382 C384 S116 D118 E119 K222 S255 L256 G257 G258 K259 L260 R375 L379 R380 C382 2.7.7.7 Q9Y253 27284197 GPHMATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSAS 5kfi A 1.65 BS01 NUC T 1 Q38 Y39 W42 R61 S62 W64 K86 L89 R93 K293 K311 R313 P316 K317 T318 G320 C321 S322 K323 N324 P326 G327 R351 Q41 Y42 W45 R64 S65 W67 K89 L92 R96 K291 K309 R311 P314 K315 T316 G318 C319 S320 K321 N322 P324 G325 R349 2.7.7.7 Q9Y253 27284197 GPHMATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSAS 5kfq A 1.55 BS02 NUC P 1 D13 F17 F18 I48 A49 R61 S113 D115 E116 S257 L258 G259 G260 K261 L262 K376 L381 R382 C384 D16 F20 F21 I51 A52 R64 S116 D118 E119 S255 L256 G257 G258 K259 L260 K374 L379 R380 C382 2.7.7.7 Q9Y253 27284197 GPHMATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSAS 5kg6 A 1.55 BS01 NUC T 1 Q38 Y39 W42 R61 S62 W64 K86 R93 K311 R313 P316 K317 T318 G320 C321 S322 K323 N324 P326 G327 R351 Q41 Y42 W45 R64 S65 W67 K89 R96 K310 R312 P315 K316 T317 G319 C320 S321 K322 N323 P325 G326 R350 2.7.7.7 Q9Y253 27284197 GPHMATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPETVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSAS 5khd R 1.75 BS01 C2E R 1 K84 R114 S123 I124 R125 Q126 K2 R32 S41 I42 R43 Q44 F2RCL8 25171413 PKLVLDLERLAHVPQEKAGPLQRYAATIQSQRGDYNGKVLSIRQDDLRTLAVIYDQSPSVLTEQLISWGVLDA 5khd R 1.75 BS03 C2E A 1 I110 Q113 R114 I124 R125 D128 I28 Q31 R32 I42 R43 D46 F2RCL8 25171413 PKLVLDLERLAHVPQEKAGPLQRYAATIQSQRGDYNGKVLSIRQDDLRTLAVIYDQSPSVLTEQLISWGVLDA 5khd R 1.75 BS04 C2E A 2 R114 G115 D116 N118 R32 G33 D34 N36 F2RCL8 25171413 PKLVLDLERLAHVPQEKAGPLQRYAATIQSQRGDYNGKVLSIRQDDLRTLAVIYDQSPSVLTEQLISWGVLDA 5khd A 1.75 BS01 C2E R 1 Y106 I110 Q113 R114 R125 D127 D128 Y23 I27 Q30 R31 R42 D44 D45 F2RCL8 25171413 KLVLDLERLAHVPQEKAGPLQRYAATIQSQRGDYNGKVLSIRQDDLRTLAVIYDQSPSVLTEQLISWGVLDA 5khd A 1.75 BS02 C2E R 3 R114 G115 D116 R31 G32 D33 F2RCL8 25171413 KLVLDLERLAHVPQEKAGPLQRYAATIQSQRGDYNGKVLSIRQDDLRTLAVIYDQSPSVLTEQLISWGVLDA