2n94 A BS01 ZN A 1 C5 C8 C25 C29 C8 C11 C28 C32 P38772 27139642 GPHMAVLCGVCGIKEFKYKCPRCLVQTCSLECSKKHKTRDNCSGQTHD 2n94 A BS02 ZN A 2 C17 C20 H33 C39 C20 C23 H36 C42 P38772 27139642 GPHMAVLCGVCGIKEFKYKCPRCLVQTCSLECSKKHKTRDNCSGQTHD 2n95 A BS01 ZN A 1 C8 C11 C28 C32 C11 C14 C31 C35 P46973 27139642 GPHMVSSAVKCGICRGVDGKYKCPKCGVRYCSLKCYKDAAKHVHKESEQ 2n95 A BS02 ZN A 2 C20 C23 H39 H41 C23 C26 H42 H44 P46973 27139642 GPHMVSSAVKCGICRGVDGKYKCPKCGVRYCSLKCYKDAAKHVHKESEQ 4rpw A 2.73 BS01 BLA A 1 C18 Y177 Y199 F204 D208 I209 P210 A213 Y217 R253 V255 S256 I258 H259 Y262 M266 S271 S273 C3 Y162 Y184 F189 D193 I194 P195 A198 Y202 R238 V240 S241 I243 H244 Y247 M251 S256 S258 Q097N3 TNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCTQVSGTRYVPYEVRTACEFLGEVMSSLLAAK 4rq9 A 2.50 BS01 BLA A 1 C18 I175 Y199 F204 D208 I209 P210 A213 Y217 R223 R253 V255 S256 I258 H259 Y262 M266 S271 S273 L285 S287 H289 C3 I160 Y184 F189 D193 I194 P195 A198 Y202 R208 R238 V240 S241 I243 H244 Y247 M251 S256 S258 L270 S272 H274 Q097N3 TNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCHQVSGTRYVPYEVRTACEFLGEVMSSLLAAK 4zij A 1.78 BS01 SFQ A 1 H32 Q35 F36 L40 P163 T168 N170 M171 F174 H32 Q35 F36 L40 P163 T168 N170 M171 F174 P0AEG4 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 4zj0 A 1.50 BS01 RET A 1 V62 W106 K108 V62 W106 K108 P50120 25478840 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTLVIDQDGDNFKTKTTSTFRNWDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 4zj0 B 1.50 BS01 RET B 1 F16 Y19 M20 I25 A33 T51 W60 V62 L77 W106 K108 F16 Y19 M20 I25 A33 T51 W60 V62 L77 W106 K108 P50120 25478840 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTLVIDQDGDNFKTKTTSTFRNWDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 4zof A 1.80 BS01 MG A 1 S119 E252 S95 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zof A 1.80 BS02 MG A 2 D251 E252 D227 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zof A 1.80 BS03 PRP A 1 V106 G107 G109 G110 N117 S119 T120 K135 N138 A140 A141 S142 S143 G146 G147 E252 V82 G83 G85 G86 N93 S95 T96 K111 N114 A116 A117 S118 S119 G122 G123 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zof A 1.80 BS04 59L A 1 V106 T108 H136 G137 N138 A179 H183 Y186 R193 G206 V82 T84 H112 G113 N114 A155 H159 Y162 R169 G182 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zof B 1.80 BS01 MG B 1 S119 E252 S95 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zof B 1.80 BS02 MG B 2 D251 E252 D227 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zof B 1.80 BS03 PRP B 1 V106 G107 G109 G110 N117 S119 T120 K135 N138 A140 A141 S142 S143 G146 G147 E252 V82 G83 G85 G86 N93 S95 T96 K111 N114 A116 A117 S118 S119 G122 G123 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zof B 1.80 BS04 59L B 1 V106 T108 G137 N138 A179 H183 Y186 R193 N203 G206 V82 T84 G113 N114 A155 H159 Y162 R169 N179 G182 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zoj A 1.96 BS01 MG A 1 D251 E252 D227 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zoj A 1.96 BS02 MG A 2 S119 E252 S95 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zoj A 1.96 BS03 PRP A 1 G107 G109 G110 N117 S119 T120 K135 N138 R139 A140 A141 S142 S143 G146 G147 E252 G83 G85 G86 N93 S95 T96 K111 N114 R115 A116 A117 S118 S119 G122 G123 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zoj A 1.96 BS04 61L A 1 M86 G137 N138 A179 P180 H183 Y186 A190 R193 G206 M62 G113 N114 A155 P156 H159 Y162 A166 R169 G182 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zoj B 1.96 BS01 MG B 1 S119 E252 S95 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zoj B 1.96 BS02 MG B 2 D251 E252 D227 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zoj B 1.96 BS03 PRP B 1 V106 G107 G109 G110 N117 S119 T120 K135 N138 R139 A140 A141 S142 S143 G147 E252 V82 G83 G85 G86 N93 S95 T96 K111 N114 R115 A116 A117 S118 S119 G123 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zoj B 1.96 BS04 61L B 1 M86 G137 N138 A179 P180 H183 Y186 A190 G206 M62 G113 N114 A155 P156 H159 Y162 A166 G182 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zok A 2.34 BS01 MG A 1 S119 D251 E252 S95 D227 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zok A 2.34 BS02 MG A 2 D111 D251 E252 D87 D227 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zok A 2.34 BS03 PRP A 1 V106 G107 G109 G110 N117 S119 T120 K135 N138 A140 A141 S142 S143 G146 G147 E252 V82 G83 G85 G86 N93 S95 T96 K111 N114 A116 A117 S118 S119 G122 G123 E228 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zok A 2.34 BS04 62L A 1 N138 P180 H183 R187 A190 A191 N114 P156 H159 R163 A166 A167 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zok B 2.34 BS01 MG B 1 G107 S119 D251 E252 G83 S94 D226 E227 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zok B 2.34 BS02 MG B 2 D251 E252 D226 E227 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zok B 2.34 BS03 PRP B 1 V106 G107 G109 G110 N117 S119 T120 K135 N138 A141 S142 S143 G146 G147 E252 V82 G83 G85 G86 N92 S94 T95 K110 N113 A116 S117 S118 G121 G122 E227 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 4zr6 A 2.60 BS01 4QW A 1 Y89 S142 W143 T144 Y185 C187 C188 Y192 Y85 S138 W139 T140 Y176 C178 C179 Y183 P58154 DRADILYNIRQTSRPDVIPTRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zr6 A 2.60 BS02 4QW E 1 W53 R104 L112 M114 W49 R100 L108 M110 P58154 DRADILYNIRQTSRPDVIPTRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zr6 B 2.60 BS01 4QW A 1 W53 R104 M114 W51 R100 M110 P58154 RADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPSEYFSQYSRFEILVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zr6 B 2.60 BS02 4QW B 1 Y89 S142 W143 T144 Y185 C187 C188 Y192 Y85 S138 W139 T140 Y173 C175 C176 Y180 P58154 RADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPSEYFSQYSRFEILVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zr6 C 2.60 BS01 4QW B 1 W53 R104 M114 W53 R104 M114 P58154 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zr6 C 2.60 BS02 4QW C 1 Y89 S142 W143 T144 Y185 C187 C188 Y192 Y89 S142 W143 T144 Y179 C181 C182 Y186 P58154 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zr6 D 2.60 BS01 4QW C 1 W53 R104 M114 W52 R103 M113 P58154 DRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zr6 D 2.60 BS02 4QW D 1 Y89 S142 W143 T144 Y185 C187 C188 Y192 Y88 S141 W142 T143 Y180 C182 C183 Y187 P58154 DRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zr6 E 2.60 BS01 4QW D 1 W53 R104 M114 W52 R103 M113 P58154 DRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zr6 E 2.60 BS02 4QW E 1 Y89 S142 W143 T144 Y185 C187 C188 Y192 Y88 S141 W142 T143 Y180 C182 C183 Y187 P58154 DRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zxn A 2.20 BS01 ZN A 1 E48 H52 D56 H336 E29 H33 D37 H317 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5a0w A 2.20 BS01 NUC B 1 G20 D21 G22 Y25 Y29 K30 R33 R37 T41 Q42 K43 T76 R77 R124 T150 H152 D154 R157 N164 S166 L167 G16 D17 G18 Y21 Y25 K26 R29 R33 T37 Q38 K39 T72 R73 R120 T146 H148 D150 R153 N160 S162 L163 3.1.-.- P21505 ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHLNPLP 5a0w A 2.20 BS02 NUC C 1 D21 G31 N32 R33 S34 E35 Y36 R37 K66 S67 K68 Q70 R81 S83 S84 K85 A116 G118 D119 K120 R124 R126 W128 K130 H158 D17 G27 N28 R29 S30 E31 Y32 R33 K62 S63 K64 Q66 R77 S79 S80 K81 A112 G114 D115 K116 R120 R122 W124 K126 H154 3.1.-.- P21505 ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHLNPLP 5a0w A 2.20 BS03 MN A 1 D21 A116 D17 A112 3.1.-.- P21505 ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHLNPLP 5a0w D 2.20 BS01 NUC E 1 G20 D21 G22 Y25 L27 Y29 K30 R33 R37 T41 Q42 K43 T76 R77 R124 T150 H152 D154 H156 R157 N164 S166 L167 G16 D17 G18 Y21 L23 Y25 K26 R29 R33 T37 Q38 K39 T72 R73 R120 T146 H148 D150 H152 R153 N160 S162 L163 3.1.-.- P21505 ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHLNPLPPEAAALEHH 5a0w D 2.20 BS02 NUC F 1 D21 G31 N32 R33 S34 E35 Y36 R37 S67 K68 Q70 E79 R81 S83 S84 K85 A116 D119 K120 T121 R124 R126 W128 H158 D17 G27 N28 R29 S30 E31 Y32 R33 S63 K64 Q66 E75 R77 S79 S80 K81 A112 D115 K116 T117 R120 R122 W124 H154 3.1.-.- P21505 ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHLNPLPPEAAALEHH 5a0w D 2.20 BS03 MN D 1 D21 Q42 A116 D17 Q38 A112 3.1.-.- P21505 ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHLNPLPPEAAALEHH 5a0w G 2.20 BS01 NUC H 1 G20 D21 G22 Y25 Y29 K30 R33 R37 T41 Q42 K43 T76 R77 R124 T150 H152 D154 R157 N164 S166 L167 G16 D17 G18 Y21 Y25 K26 R29 R33 T37 Q38 K39 T72 R73 R120 T146 H148 D150 R153 N160 S162 L163 3.1.-.- P21505 ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHL 5a0w G 2.20 BS02 NUC I 1 D21 N32 R33 S34 E35 Y36 R37 S67 K68 Q70 R81 S83 S84 K85 A116 G118 D119 K120 R124 R126 W128 K130 H158 D17 N28 R29 S30 E31 Y32 R33 S63 K64 Q66 R77 S79 S80 K81 A112 G114 D115 K116 R120 R122 W124 K126 H154 3.1.-.- P21505 ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHL 5a0w G 2.20 BS03 MN G 1 D21 A116 D17 A112 3.1.-.- P21505 ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHL 5a0y A 1.10 BS01 F43 A 1 A144 V145 V146 Q147 M150 Q230 M233 A243 A143 V144 V145 Q146 M149 Q229 M232 A242 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y A 1.10 BS02 COM A 1 Y333 F443 Y444 Y332 F442 Y443 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y A 1.10 BS03 TP7 A 1 R270 L320 M324 S325 F330 F443 M480 N481 V482 R269 L319 M323 S324 F329 F442 M479 N480 V481 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y A 1.10 BS04 MG A 1 K11 F14 E15 K10 F13 E14 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y A 1.10 BS05 F43 D 1 G326 G327 V328 G329 F330 T331 Q332 Y333 F396 G397 G442 F443 G325 G326 V327 G328 F329 T330 Q331 Y332 F395 G396 G441 F442 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y A 1.10 BS06 TP7 D 1 R225 K256 H257 R224 K255 H256 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y B 1.10 BS01 COM A 1 F361 S365 Y367 F360 S364 Y366 2.8.4.1 P11560 AKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPSVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAGTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI 5a0y B 1.10 BS02 TP7 A 1 F361 F362 Y367 G368 G369 H379 I380 V381 F360 F361 Y366 G367 G368 H378 I379 V380 2.8.4.1 P11560 AKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPSVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAGTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI 5a0y B 1.10 BS03 F43 D 1 S365 I366 Y367 S364 I365 Y366 2.8.4.1 P11560 AKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPSVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAGTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI 5a0y C 1.10 BS01 COM A 1 L117 R120 L116 R119 2.8.4.1 P11562 AQYYPGTTKVAQNRRNFCNPEYELEKLREISDEDVVKILGHRAPGEEYPSVHPPLEEMDEPEDAIREMVEPIDGAKAGDRVRYIQFTDSMYFAPAQPYVRSRAYLCRYRGADAGTLSGRQIIETRERDLEKISKELLETEFFDPARSGVRGKSVHGHSLRLDEDGMMFDMLRRQIYNKDTGRVEMVKNQIGDELDEPVDLGEPLDEETLMEKTTIYRVDGEAYRDDVEAVEIMQRIHVLRSQGGFNLE 5a0y C 1.10 BS02 F43 D 1 L117 S118 G119 R120 K153 S154 V155 H156 H158 L116 S117 G118 R119 K152 S153 V154 H155 H157 2.8.4.1 P11562 AQYYPGTTKVAQNRRNFCNPEYELEKLREISDEDVVKILGHRAPGEEYPSVHPPLEEMDEPEDAIREMVEPIDGAKAGDRVRYIQFTDSMYFAPAQPYVRSRAYLCRYRGADAGTLSGRQIIETRERDLEKISKELLETEFFDPARSGVRGKSVHGHSLRLDEDGMMFDMLRRQIYNKDTGRVEMVKNQIGDELDEPVDLGEPLDEETLMEKTTIYRVDGEAYRDDVEAVEIMQRIHVLRSQGGFNLE 5a0y D 1.10 BS01 F43 A 1 G326 G327 V328 G329 F330 T331 Q332 Y333 F396 G397 G442 F443 G325 G326 V327 G328 F329 T330 Q331 Y332 F395 G396 G441 F442 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y D 1.10 BS02 TP7 A 1 R225 K256 H257 R224 K255 H256 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y D 1.10 BS03 F43 D 1 A144 V145 V146 Q147 M150 Q230 M233 A243 A143 V144 V145 Q146 M149 Q229 M232 A242 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y D 1.10 BS04 COM D 1 Y333 F443 Y444 Y332 F442 Y443 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y D 1.10 BS05 TP7 D 1 R270 L320 M324 S325 F330 F443 M480 N481 V482 R269 L319 M323 S324 F329 F442 M479 N480 V481 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y D 1.10 BS06 MG D 1 K11 F14 E15 K10 F13 E14 2.8.4.1 P11558 ADKLFINALKKKFEESPEEKKTTFYTLGGWKQSERKTEFVNAGKEVAAKRGIPQYNPDIGTPLGQRVLMPYQVSTTDTYVEGDDLHFVNNAAMQQMWDDIRRTVIVGLNHAHAVIEKRLGKEVTPETITHYLETVNHAMPGAAVVQEHMVETHPALVADSYVKVFTGNDEIADEIDPAFVIDINKQFPEDQAETLKAEVGDGIWQVVRIPTIVSRTCDGATTSRWSAMQIGMSMISAYKQAAGEAATGDFAYAAKHAEVIHMGTYLPVRRARGENEPGGVPFGYLADICQSSRVNYEDPVRVSLDVVATGAMLYDQIWLGSYMSGGVGFTQYATAAYTDNILDDFTYFGKEYVEDKYGLCEAPNNMDTVLDVATEVTFYGLEQYEEYPALLEDQFGGSQRAAVVAAAAGCSTAFATGNAQTGLSGWYLSMYLHKEQHSRLGFYGYDLQDQCGASNVFSIRGDEGLPLELRGPNYPNYAMNVGHQGEYAGISQAPHAARGDAFVFNPLVKIAFADDNLVFDFTNVRGEFAKGALREFEPAGERALITPA 5a0y E 1.10 BS01 F43 A 1 S365 I366 Y367 S364 I365 Y366 2.8.4.1 P11560 AKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPSVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAGTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI 5a0y E 1.10 BS02 COM D 1 F361 S365 Y367 F360 S364 Y366 2.8.4.1 P11560 AKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPSVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAGTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI 5a0y E 1.10 BS03 TP7 D 1 F361 F362 Y367 G369 H379 I380 V381 F360 F361 Y366 G368 H378 I379 V380 2.8.4.1 P11560 AKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGNAESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVLGRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGLAYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAARAAQGVSSTLLYYNDLIEFETGLPSVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDAGTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI 5a0y F 1.10 BS01 F43 A 1 L117 S118 G119 K153 S154 V155 H156 H158 L116 S117 G118 K152 S153 V154 H155 H157 2.8.4.1 P11562 AQYYPGTTKVAQNRRNFCNPEYELEKLREISDEDVVKILGHRAPGEEYPSVHPPLEEMDEPEDAIREMVEPIDGAKAGDRVRYIQFTDSMYFAPAQPYVRSRAYLCRYRGADAGTLSGRQIIETRERDLEKISKELLETEFFDPARSGVRGKSVHGHSLRLDEDGMMFDMLRRQIYNKDTGRVEMVKNQIGDELDEPVDLGEPLDEETLMEKTTIYRVDGEAYRDDVEAVEIMQRIHVLRSQGGFNLE 5a0y F 1.10 BS02 COM D 1 L117 R120 L116 R119 2.8.4.1 P11562 AQYYPGTTKVAQNRRNFCNPEYELEKLREISDEDVVKILGHRAPGEEYPSVHPPLEEMDEPEDAIREMVEPIDGAKAGDRVRYIQFTDSMYFAPAQPYVRSRAYLCRYRGADAGTLSGRQIIETRERDLEKISKELLETEFFDPARSGVRGKSVHGHSLRLDEDGMMFDMLRRQIYNKDTGRVEMVKNQIGDELDEPVDLGEPLDEETLMEKTTIYRVDGEAYRDDVEAVEIMQRIHVLRSQGGFNLE 5aqz A 1.65 BS01 SGV A 1 G230 E268 K271 R272 S275 G339 S340 R342 I343 D366 G232 E270 K273 R274 S277 G341 S342 R344 I345 D368 3.6.3.51 P0DMV8 27119979 GSMAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILIKSTRAAA 5ar0 A 1.90 BS01 GB8 A 1 Y15 N35 G201 G202 G230 E268 K271 R272 S275 G339 S340 R342 I343 D366 Y13 N31 G197 G198 G226 E264 K267 R268 S271 G335 S336 R338 I339 D362 3.6.3.51 P0DMV8 27119979 KAAAIGIDLGTTYSCVGVFQKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILIKS 5axo A 1.39 BS01 ZN A 1 H72 H74 H150 H70 H72 H148 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5axo A 1.39 BS02 ZN A 2 D76 H77 H215 D74 H75 H213 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5axo A 1.39 BS03 LMP A 1 W5 H72 D76 H77 Q113 H150 S175 T177 H215 E217 R252 W3 H70 D74 H75 Q111 H148 S173 T175 H213 E215 R250 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5axr A 2.10 BS01 ZN A 1 H72 H74 H150 H70 H72 H148 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5axr A 2.10 BS02 ZN A 2 D76 H77 H215 D74 H75 H213 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5axr A 2.10 BS03 COM A 1 W5 H72 H74 D76 H77 Q113 L117 H150 V179 H215 W3 H70 H72 D74 H75 Q111 L115 H148 V177 H213 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5aya A 2.02 BS01 ZN A 1 H72 H74 H150 H70 H72 H148 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5aya A 2.02 BS02 ZN A 2 D76 H77 H215 D74 H75 H213 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5aya A 2.02 BS03 X8Z A 1 H72 H74 D76 H77 H150 T177 V179 H215 E217 R252 H70 H72 D74 H75 H148 T175 V177 H213 E215 R250 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5b15 A 1.39 BS01 ZN A 1 H72 H74 H150 H70 H72 H148 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5b15 A 1.39 BS02 ZN A 2 D76 H77 H215 D74 H75 H213 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5b15 A 1.39 BS03 DQM A 1 W5 D76 H77 Q113 H150 S175 T177 H215 E217 R252 W3 D74 H75 Q111 H148 S173 T175 H213 E215 R250 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5b1u A 1.57 BS01 ZN A 1 H72 H74 H150 H70 H72 H148 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5b1u A 1.57 BS02 ZN A 2 D76 H77 H215 D74 H75 H213 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5b1u A 1.57 BS03 HIW A 1 W5 D76 H77 Q113 L117 H150 S175 T177 H215 E217 V218 R252 W3 D74 H75 Q111 L115 H148 S173 T175 H213 E215 V216 R250 3.5.2.6 G5ELM3 RDWSSPQQPFTIYGNTHYVGTGGISAVLLSSPQGHILVDGTTEKGAQVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKLTGATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPGSAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQGKCKDVVFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEKLSCDIAIAAHPEVNDMWTRQQRAAKEGNSAYVDNGACRAIAAAGRKRLETRLASEK 5b1w A 3.05 BS01 CA A 1 V143 N145 E149 E231 V39 N41 E45 E127 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1w A 3.05 BS02 CA A 2 E195 S197 E201 N218 D219 E91 S93 E97 N114 D115 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1w B 3.05 BS01 CA B 1 V143 N145 E149 E231 V39 N41 E45 E127 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1w B 3.05 BS02 CA B 2 E195 S197 E201 N218 D219 E91 S93 E97 N114 D115 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1w C 3.05 BS01 CA C 1 V143 N145 E149 E231 V39 N41 E45 E127 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEM 5b1w C 3.05 BS02 CA C 2 E195 S197 E201 N218 D219 E91 S93 E97 N114 D115 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEM 5b1w D 3.05 BS01 CA D 1 V143 N145 E149 E231 V39 N41 E45 E127 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEM 5b1w D 3.05 BS02 CA D 2 E195 S197 E201 N218 D219 E91 S93 E97 N114 D115 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEM 5b1x A 2.90 BS01 NAG A 1 N207 R209 Q226 N103 R105 Q122 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1x A 2.90 BS02 CA A 1 V143 N145 E149 E231 V39 N41 E45 E127 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1x A 2.90 BS03 CA A 2 E195 S197 E201 N218 D219 E91 S93 E97 N114 D115 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1x B 2.90 BS01 NAG B 1 N207 R209 V220 Q226 N103 R105 V116 Q122 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1x B 2.90 BS02 CA B 1 V143 N145 E149 E231 V39 N41 E45 E127 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1x B 2.90 BS03 CA B 2 E195 S197 E201 N218 D219 E91 S93 E97 N114 D115 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMK 5b1x C 2.90 BS01 NAG C 1 N207 R209 N218 V220 Q226 N103 R105 N114 V116 Q122 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMM 5b1x C 2.90 BS02 CA C 1 V143 N145 E149 E231 V39 N41 E45 E127 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMM 5b1x C 2.90 BS03 CA C 2 E195 S197 E201 N218 D219 E91 S93 E97 N114 D115 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMM 5b1x D 2.90 BS01 NAG D 1 N207 R209 N218 Q226 N103 R105 N114 Q122 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMM 5b1x D 2.90 BS02 CA D 1 V143 N145 E149 E231 V39 N41 E45 E127 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMM 5b1x D 2.90 BS03 CA D 2 E195 S197 E201 N218 D219 E91 S93 E97 N114 D115 Q9UMR7 27015765 SCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMM 5bsm A 2.32 BS01 ATP A 1 S189 S190 G191 T192 T193 K197 H237 A309 A310 P311 Q331 G332 Y333 G334 M335 T336 D420 I432 R435 K526 S182 S183 G184 T185 T186 K190 H230 A302 A303 P304 Q324 G325 Y326 G327 M328 T329 D413 I425 R428 K519 6.2.1.12 O24146 26412334 VDIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRAKLA 5bsm B 2.32 BS01 ATP B 1 S189 S190 G191 T192 T193 K197 H237 A309 A310 P311 Q331 G332 Y333 G334 M335 T336 D420 I432 R435 K526 S182 S183 G184 T185 T186 K190 H230 A302 A303 P304 Q324 G325 Y326 G327 M328 T329 D413 I425 R428 K519 6.2.1.12 O24146 26412334 VDIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRAKLA 5bsr A 1.50 BS01 COA A 1 L110 P234 H237 Y239 K260 F261 V281 P283 A309 K443 G444 F445 F506 L102 P226 H229 Y231 K252 F253 V273 P275 A301 K435 G436 F437 F498 6.2.1.12 O24146 26412334 DIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRAKL 5bsr A 1.50 BS02 AMP A 1 A309 P311 G332 G334 M335 T336 D420 R435 K437 K441 Q446 A301 P303 G324 G326 M327 T328 D412 R427 K429 K433 Q438 6.2.1.12 O24146 26412334 DIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRAKL 5bst A 1.61 BS01 4UU A 1 H237 Y239 S243 A309 A310 P311 Q331 G332 Y333 G334 M335 T336 P340 V341 M344 D420 I432 R435 K437 K441 Q446 H230 Y232 S236 A302 A303 P304 Q324 G325 Y326 G327 M328 T329 P333 V334 M337 D413 I425 R428 K430 K434 Q439 6.2.1.12 O24146 26412334 VDIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRAKL 5bsu A 1.75 BS01 4UV A 1 H237 Y239 S243 M306 G308 A309 A310 P311 Q331 G332 G334 M335 T336 P340 V341 M344 D420 I432 R435 K437 K441 Q446 H230 Y232 S236 M299 G301 A302 A303 P304 Q324 G325 G327 M328 T329 P333 V334 M337 D413 I425 R428 K430 K434 Q439 6.2.1.12 O24146 26412334 VDIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRAKL 5bsv A 1.70 BS01 4UW A 1 H237 Y239 S243 M306 S307 A309 A310 P311 Q331 G332 G334 M335 T336 P340 V341 M344 D420 I432 R435 K437 K441 Q446 H230 Y232 S236 M299 S300 A302 A303 P304 Q324 G325 G327 M328 T329 P333 V334 M337 D413 I425 R428 K430 K434 Q439 6.2.1.12 O24146 26412334 VDIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRAKL 5bsw A 2.10 BS01 4UW A 1 S189 H237 I238 Y239 S243 A309 A310 P311 Q331 G332 Y333 G334 M335 T336 P340 M343 D419 I431 R434 K525 S181 H229 I230 Y231 S235 A301 A302 P303 Q323 G324 Y325 G326 M327 T328 P332 M335 D411 I423 R426 K517 6.2.1.12 O24146 26412334 DIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRAK 5bsw B 2.10 BS01 4UW B 1 H237 I238 Y239 S243 M306 G308 A309 A310 P311 Q331 G332 Y333 G334 M335 T336 P340 M343 D419 I431 R434 K525 H230 I231 Y232 S236 M299 G301 A302 A303 P304 Q324 G325 Y326 G327 M328 T329 P333 M336 D412 I424 R427 K518 6.2.1.12 O24146 26412334 VDIIFRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTPAEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPEGCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKILRKDLRA 5c51 A 3.43 BS01 NUC P 1 R579 S764 P765 D769 N803 R853 L860 A862 N864 R869 R948 H1134 R447 S551 P552 D556 N590 R640 L647 A649 N651 R656 R735 H889 2.7.7.7 P54098 26124101 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKRFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 5c51 A 3.43 BS02 NUC T 1 S305 S306 K498 K561 S593 Q595 M596 R597 N803 K806 R807 T849 I850 V855 P857 T861 R948 Y951 G952 Y955 G956 G958 Q959 F961 M1093 T1094 S1095 N1098 Q1102 S216 S217 K385 K429 S461 Q463 M464 R465 N590 K593 R594 T636 I637 V642 P644 T648 R735 Y738 G739 Y742 G743 G745 Q746 F748 M848 T849 S850 N853 Q857 2.7.7.7 P54098 26124101 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKRFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 5c51 A 3.43 BS03 MG A 1 D890 V891 D892 D1135 D677 V678 D679 D890 2.7.7.7 P54098 26124101 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKRFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 5c51 A 3.43 BS04 1RY A 1 R853 D890 V891 D892 S893 Q894 R943 K947 R948 Y951 D1135 R640 D677 V678 D679 S680 Q681 R730 K734 R735 Y738 D890 2.7.7.7 P54098 26124101 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKRFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 5c52 A 3.64 BS01 NUC T 1 S305 S306 K496 K498 K561 S593 Q595 M596 R597 N803 K806 R807 T849 I850 V855 P857 T861 I948 Y951 G952 Y955 G956 G958 F961 K1050 E1091 M1093 T1094 S1095 N1098 Q1102 S216 S217 K383 K385 K429 S461 Q463 M464 R465 N590 K593 R594 T636 I637 V642 P644 T648 I735 Y738 G739 Y742 G743 G745 F748 K805 E846 M848 T849 S850 N853 Q857 2.7.7.7 P54098 26124101 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 5c52 A 3.64 BS02 NUC P 1 R579 S764 P765 K768 D769 S799 N803 L860 A862 N864 R869 R447 S551 P552 K555 D556 S586 N590 L647 A649 N651 R656 2.7.7.7 P54098 26124101 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 5c52 A 3.64 BS03 1RY A 1 R853 V891 D892 S893 Q894 E895 R943 K947 Y951 Q1102 D1135 R640 V678 D679 S680 Q681 E682 R730 K734 Y738 Q857 D890 2.7.7.7 P54098 26124101 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 5c52 A 3.64 BS04 MG A 1 D890 D1135 D677 D890 2.7.7.7 P54098 26124101 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 5c52 A 3.64 BS05 MG A 2 D890 V891 D892 D1135 D677 V678 D679 D890 2.7.7.7 P54098 26124101 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 5cco A 2.33 BS01 UMP A 1 G78 K79 I80 D81 Y84 G89 G77 K78 I79 D80 Y83 G88 A4ZF98 27112567 TNTLQVKLLSKNARMPERNHKTDAGYDIFSAETVVLEPQEKAVIKTDVAVSIPEGYVGLLTSRSGVSSKTHLVIETGKIDAGYHGNLGINIKNDHEDDKMQTIFLRNIDNEKIFEKERHLYKLGSYRIEKGERIAQLVIVPIWTPELKQVEEFESVSERGEKGFGSS 5cct A 2.40 BS01 DUP A 1 G78 K79 I80 D81 Y84 G89 G77 K78 I79 D80 Y83 G88 A4ZF98 27112567 TNTLQVKLLSKNARMPERNHKTDAGYDIFSAETVVLEPQEKAVIKTDVAVSIPEGYVGLLTSRSGVSSKTHLVIETGKIDAGYHGNLGINIKNDHEDDKMQTIFLRNIDNEKIFEKERHLYKLGSYRIEKGERIAQLVIVPIWTPELKQVEEFESVSERGEKSFGSSGV 5d8n A 2.15 BS01 MG A 1 V262 N263 A264 V208 N209 A210 3.4.11.1,3.4.11.5 Q10712 AGDTLGLTRPNESDAPKISIGAKDTAVVQWQGDLLAIGATENDMARDENSKFKNPLLQQLDSELNGLLSAASSEEDFSGKSGQSVNLRFPGGRITLVGLGSSASSPTSYHSLGQAAAAAAKSSQARNIAVALASTDGLSAESKINSASAIATGVVLGSFEDNRFRSESKKSTLESLDILGLGTGPEIERKIKYAEHVCAGVILGRELVNAPANIVTPAVLAEEAKKIASTYSDVISVNILDAEQCKELKMGAYLAVAAAATENPPYFIHLCFKTPTKERKTKLALVGKGLTFDSGELMKNDMGGAAAVLGAAKALGEIRPSRVEVHFIVAACENMISAEGMRPGDIVTASNGKTIEVNNTDAEGRLTLADALIYACNQGVEKIIDLATLTGAIMVALGPSVAGAFTPNDDLAREVVEAAEASGEKLWRMPMEESYWESMKSGVADMINTGPGNGGAITGALFLKQFVDEKVQWLHLDVAGPVWSDEKKNATGYGVSTLVEWVLRN 5d8n B 2.15 BS01 MG B 1 V262 A264 V208 A210 3.4.11.1,3.4.11.5 Q10712 AGDTLGLTRPNESDAPKISIGAKDTAVVQWQGDLLAIGATENDMARDENSKFKNPLLQQLDSELNGLLSAASSEEDFSGKSGQSVNLRFPGGRITLVGLGSSASSPTSYHSLGQAAAAAAKSSQARNIAVALASTDGLSAESKINSASAIATGVVLGSFEDNRFRSESKKSTLESLDILGLGTGPEIERKIKYAEHVCAGVILGRELVNAPANIVTPAVLAEEAKKIASTYSDVISVNILDAEQCKELKMGAYLAVAAAATENPPYFIHLCFKTPTKERKTKLALVGKGLTFDSGLMKNDMGGAAAVLGAAKALGEIRPSRVEVHFIVAACENMISAEGMRPGDIVTASNGKTIEVNNTDAEGRLTLADALIYACNQGVEKIIDLATLTGAIMVALGPSVAGAFTPNDDLAREVVEAAEASGEKLWRMPMEESYWESMKSGVADMINTGPGNGGAITGALFLKQFVDEKVQWLHLDVAGPVWSDEKKNATGYGVSTLVEWVLRN 5d8n C 2.15 BS01 MG C 1 V262 A264 V208 A210 3.4.11.1,3.4.11.5 Q10712 AGDTLGLTRPNESDAPKISIGAKDTAVVQWQGDLLAIGATENDMARDENSKFKNPLLQQLDSELNGLLSAASSEEDFSGKSGQSVNLRFPGGRITLVGLGSSASSPTSYHSLGQAAAAAAKSSQARNIAVALASTDGLSAESKINSASAIATGVVLGSFEDNRFRSESKKSTLESLDILGLGTGPEIERKIKYAEHVCAGVILGRELVNAPANIVTPAVLAEEAKKIASTYSDVISVNILDAEQCKELKMGAYLAVAAAATENPPYFIHLCFKTPTKERKTKLALVGKGLTFDSGLMKNDMGGAAAVLGAAKALGEIRPSRVEVHFIVAACENMISAEGMRPGDIVTASNGKTIEVNNTDAEGRLTLADALIYACNQGVEKIIDLATLTGAIMVALGPSVAGAFTPNDDLAREVVEAAEASGEKLWRMPMEESYWESMKSGVADMINTGPGNGGAITGALFLKQFVDEKVQWLHLDVAGPVWSDEKKNATGYGVSTLVEWVLRN 5dai A 2.00 BS01 III B 1 M41 S44 R45 V46 V47 L48 P126 L128 P226 L242 A244 P245 R246 V247 M40 S43 R44 V45 V46 L47 P125 L127 P225 L241 A243 P244 R245 V246 Q5JF32 PFEVVFDGAKEFADLIATASNLIDEAAFKFTEEGISMRAMDPSRVVLIDLNLPESIFSKYEVEEPETIGINMDQFKKILKRGKAKDTLILRKGDENFLEITFEGTAKRTFRLPLIDVEELELELPELPFTAKVVLLGEVLKEGIKDASLVSDAIKFIAKENEFTMKAEGETNEVEIRLTLEDEGLLDLEVEEETKSAYGIRYLSDMVKGIGKADEVILRFGNEMPLQMEYMIRDEGRLTFLLAPRVE 5dd0 H 2.49 BS01 III P 1 W33 Y52 S55 R57 G58 E59 F101 P103 F108 T109 L110 W33 Y52 S55 R57 G58 E59 F101 P103 F108 T109 L110 27122615 QVQLQESGPGLVKPSETLSVTCAVSGVSFSSFWWGWIRQSPGKGLEWIGTIYGSSGRGEYNPSLKSRTTISRDTSKSQISLELTSVTAADTAIYYCSRGLFQPNGFSFTLTSYWFDVWGPGVPVTVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTVSWNSGSLTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYVCNVNHKPSNTKVDKRVEI 5e76 A 2.30 BS01 BGC A 1 W82 N83 W306 S308 W38 N39 W257 S259 A7LXT5 EALEAATAPLYNRAWFDYNQRSIVPIGSGRANDMYSPWNYPQFVTFQVTALDENLSGAWSGFYSVVTMANSVINAVETQSEAAKTKAIAEARLMRACAYFYMLRIWGPVILIEDNQKLVDNPVRPLNREEDVFQFIINDLNYAVDNLSEQSDKGRATSWAAKGILAKVYLARSGWNNGGTRDEGDLELARQYASDVCENSGLDLMTNYEDLFKYKNNNNQESLLAMQWVPLGEWYECNTLLSDLAFSTEVTGGVNCWSSYNGSIDMLQQYELADTLRRNATFFTKGSYYSYICIKDGGYTYKGTASPIKKGVPGGPDDDNDGKVKQMNSPLNTYILRLADVYLTYAEACLGNNSTLSDGRGLYFFNRVRERAKINKKSSITLDDIIRERRVEFGMEYSNWYDMVTWFRYLPDKMLNYFNNQWRGYRTDAIIKDEKLHFGKYDTTFLEGPEYYTAPEFTINIEAEDIFLPYPESDVIQNPLLNEPPVPYTFNE 5e76 A 2.30 BS02 XYS A 1 R65 Y84 R21 Y40 A7LXT5 EALEAATAPLYNRAWFDYNQRSIVPIGSGRANDMYSPWNYPQFVTFQVTALDENLSGAWSGFYSVVTMANSVINAVETQSEAAKTKAIAEARLMRACAYFYMLRIWGPVILIEDNQKLVDNPVRPLNREEDVFQFIINDLNYAVDNLSEQSDKGRATSWAAKGILAKVYLARSGWNNGGTRDEGDLELARQYASDVCENSGLDLMTNYEDLFKYKNNNNQESLLAMQWVPLGEWYECNTLLSDLAFSTEVTGGVNCWSSYNGSIDMLQQYELADTLRRNATFFTKGSYYSYICIKDGGYTYKGTASPIKKGVPGGPDDDNDGKVKQMNSPLNTYILRLADVYLTYAEACLGNNSTLSDGRGLYFFNRVRERAKINKKSSITLDDIIRERRVEFGMEYSNWYDMVTWFRYLPDKMLNYFNNQWRGYRTDAIIKDEKLHFGKYDTTFLEGPEYYTAPEFTINIEAEDIFLPYPESDVIQNPLLNEPPVPYTFNE 5e76 A 2.30 BS03 BGC A 2 R65 W306 M376 R21 W257 M327 A7LXT5 EALEAATAPLYNRAWFDYNQRSIVPIGSGRANDMYSPWNYPQFVTFQVTALDENLSGAWSGFYSVVTMANSVINAVETQSEAAKTKAIAEARLMRACAYFYMLRIWGPVILIEDNQKLVDNPVRPLNREEDVFQFIINDLNYAVDNLSEQSDKGRATSWAAKGILAKVYLARSGWNNGGTRDEGDLELARQYASDVCENSGLDLMTNYEDLFKYKNNNNQESLLAMQWVPLGEWYECNTLLSDLAFSTEVTGGVNCWSSYNGSIDMLQQYELADTLRRNATFFTKGSYYSYICIKDGGYTYKGTASPIKKGVPGGPDDDNDGKVKQMNSPLNTYILRLADVYLTYAEACLGNNSTLSDGRGLYFFNRVRERAKINKKSSITLDDIIRERRVEFGMEYSNWYDMVTWFRYLPDKMLNYFNNQWRGYRTDAIIKDEKLHFGKYDTTFLEGPEYYTAPEFTINIEAEDIFLPYPESDVIQNPLLNEPPVPYTFNE 5e76 A 2.30 BS04 BGC A 3 W283 M376 W234 M327 A7LXT5 EALEAATAPLYNRAWFDYNQRSIVPIGSGRANDMYSPWNYPQFVTFQVTALDENLSGAWSGFYSVVTMANSVINAVETQSEAAKTKAIAEARLMRACAYFYMLRIWGPVILIEDNQKLVDNPVRPLNREEDVFQFIINDLNYAVDNLSEQSDKGRATSWAAKGILAKVYLARSGWNNGGTRDEGDLELARQYASDVCENSGLDLMTNYEDLFKYKNNNNQESLLAMQWVPLGEWYECNTLLSDLAFSTEVTGGVNCWSSYNGSIDMLQQYELADTLRRNATFFTKGSYYSYICIKDGGYTYKGTASPIKKGVPGGPDDDNDGKVKQMNSPLNTYILRLADVYLTYAEACLGNNSTLSDGRGLYFFNRVRERAKINKKSSITLDDIIRERRVEFGMEYSNWYDMVTWFRYLPDKMLNYFNNQWRGYRTDAIIKDEKLHFGKYDTTFLEGPEYYTAPEFTINIEAEDIFLPYPESDVIQNPLLNEPPVPYTFNE 5e8w A 1.86 BS01 STU A 1 I211 G212 K213 V219 A230 K232 E245 L260 S280 D281 Y282 H283 E284 G286 K337 N338 L340 D351 I13 G14 K15 V21 A32 K34 E47 L62 S82 D83 Y84 H85 E86 G88 K139 N140 L142 D153 2.7.11.30 P36897 MTIARDIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI 5e8x A 1.45 BS01 STU A 1 V211 G212 K213 G214 V219 A230 K232 E245 L260 T280 D281 F282 H283 E284 G286 N287 K337 L340 C350 D351 V12 G13 K14 G15 V20 A31 K33 E46 L61 T81 D82 F83 H84 E85 G87 N88 K138 L141 C151 D152 2.7.11.30 P36897 TIARDIVLQESVGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIFQTVMLRHENILGFIAADNKDNGTWTQLWLVTDFHEHGNLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCICDFGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM 5e8y A 2.05 BS01 STU A 1 V250 G251 K252 V258 A275 K277 L305 T325 A326 F327 H328 A329 G331 N332 S383 N384 L386 C396 D397 V11 G12 K13 V19 A32 K34 L62 T82 A83 F84 H85 A86 G88 N89 S140 N141 L143 C153 D154 2.7.11.30 P37173 ELLPIELDTLVGKGRFAEVYKAKLKQQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLASAMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVASMADNVLADAGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSEL 5e8z A 1.51 BS01 5L4 A 1 I211 K213 G214 A230 K232 L260 S280 D281 Y282 H283 E284 G286 S287 D290 K337 L340 D351 I15 K17 G18 A34 K36 L64 S84 D85 Y86 H87 E88 G90 S91 D94 K141 L144 D155 2.7.11.30 P36897 GHMTIARDIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQE 5e90 A 2.05 BS01 5L4 A 1 V211 K213 G214 V219 A230 K232 L260 T280 D281 F282 H283 E284 G286 N287 D290 K337 L340 C350 D351 V15 K17 G18 V23 A34 K36 L64 T84 D85 F86 H87 E88 G90 N91 D94 K141 L144 C154 D155 2.7.11.30 P36897 GHMTIARDIVLQESVGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIFQTVMLRHENILGFIAADNKDNGTWTQLWLVTDFHEHGNLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCICDFGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQE 5e91 A 2.42 BS01 5L4 A 1 V250 V258 A275 K277 L305 T325 A326 F327 H328 A329 G331 N332 S383 L386 C396 D397 V11 V19 A29 K31 L59 T79 A80 F81 H82 A83 G85 N86 S137 L140 C150 D151 2.7.11.30 P37173 ELLPIELDTLVGKGRFAEVYKAKLKETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLASAMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVASMADNVLADAGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELEH 5e92 A 2.08 BS01 ANP A 1 V250 G251 G253 R254 F255 A256 V258 A275 K277 E290 L305 T325 A326 F327 H328 N332 E335 D379 K381 S383 N384 L386 C396 D397 V11 G12 G14 R15 F16 A17 V19 A30 K32 E45 L60 T80 A81 F82 H83 N87 E90 D134 K136 S138 N139 L141 C151 D152 2.7.11.30 P37173 ELLPIELDTLVGKGRFAEVYKAKLKFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLASAMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVASMADNVLADAGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELEH 5e92 A 2.08 BS02 MG A 1 N384 D397 N139 D152 2.7.11.30 P37173 ELLPIELDTLVGKGRFAEVYKAKLKFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLASAMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVASMADNVLADAGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELEH 5ep9 A 2.13 BS01 AKG A 1 M72 L114 K116 T127 H130 D132 T146 W148 M161 H207 H213 A215 R224 S228 M56 L98 K100 T111 H114 D116 T130 W132 M145 H185 H191 A193 R202 S206 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLRRPQTRQP 5ep9 A 2.13 BS02 FE A 1 H130 D132 H213 H114 D116 H191 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLRRPQTRQP 5ep9 B 2.13 BS01 AKG B 1 M72 L114 K116 T127 H130 D132 T146 W148 H207 H213 A215 R224 S228 M56 L98 K100 T111 H114 D116 T130 W132 H188 H194 A196 R205 S209 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLRR 5ep9 B 2.13 BS02 FE B 1 H130 D132 H213 H114 D116 H194 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLRR 5ep9 C 2.13 BS01 AKG C 1 M72 L114 K116 T127 H130 D132 W148 M161 H207 H213 A215 R224 S228 M56 L98 K100 T111 H114 D116 W132 M145 H176 H182 A184 R193 S197 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5ep9 C 2.13 BS02 FE C 1 H130 D132 H213 H114 D116 H182 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5ep9 D 2.13 BS01 AKG D 1 M72 L114 K116 T127 H130 D132 T146 W148 M161 H207 H213 A215 R224 S228 M56 L98 K100 T111 H114 D116 T130 W132 M145 H177 H183 A185 R194 S198 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5ep9 D 2.13 BS02 FE D 1 H130 D132 H213 H114 D116 H183 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5epa A 2.24 BS01 FE A 1 H121 D123 H210 H117 D119 H206 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa A 2.24 BS02 AKG A 1 W57 V66 K110 T118 H121 D123 W139 M152 H204 H210 A212 R221 W53 V62 K106 T114 H117 D119 W135 M148 H200 H206 A208 R217 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa B 2.24 BS01 FE B 1 H121 D123 H210 H117 D119 H206 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa B 2.24 BS02 AKG B 1 W57 V66 K110 T118 H121 D123 W139 M152 H204 H210 A212 R221 W53 V62 K106 T114 H117 D119 W135 M148 H200 H206 A208 R217 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa C 2.24 BS01 FE C 1 H121 D123 H210 H117 D119 H206 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa C 2.24 BS02 AKG C 1 V66 K110 T118 H121 D123 W139 M152 H204 H210 A212 R221 V62 K106 T114 H117 D119 W135 M148 H200 H206 A208 R217 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa D 2.24 BS01 FE D 1 H121 D123 H210 H117 D119 H206 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa D 2.24 BS02 AKG D 1 W57 V66 K110 T118 H121 D123 W139 M152 H204 H210 A212 R221 W53 V62 K106 T114 H117 D119 W135 M148 H200 H206 A208 R217 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa E 2.24 BS01 FE E 1 H121 D123 H210 H117 D119 H206 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa E 2.24 BS02 AKG E 1 W57 V66 K110 T118 H121 D123 W139 M152 H204 H210 A212 R221 W53 V62 K106 T114 H117 D119 W135 M148 H200 H206 A208 R217 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTSFAEFRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa F 2.24 BS01 FE F 1 H121 D123 H210 H117 D119 H201 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5epa F 2.24 BS02 AKG F 1 W57 V66 K110 T118 H121 D123 T137 W139 M152 H204 H210 A212 R221 W53 V62 K106 T114 H117 D119 T133 W135 M148 H195 H201 A203 R212 Q9RN60 27114534 GGPTTAENLSKEAVRFYREQGYVHIPRVLSETEVTAFRAACEEVLEKEGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKRTLPTLVHDDETGLPLNELSATLTAWIALTDVPVERGCMSYVPGSHLRAREDRQEHMTRDLADVWPDYPWQPRVAVPVRAGDVVFHHCRTVHMAEANTSDSVRMAHGVVYMDADATYRPGVQDGHLSRLSPGDPLEGELFPLVT 5equ A 2.20 BS01 FE A 1 H130 D132 H213 H114 D116 H197 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ A 2.20 BS02 AKG A 1 M72 L114 K116 T127 H130 D132 W148 M161 H207 H213 A215 R224 S228 M56 L98 K100 T111 H114 D116 W132 M145 H191 H197 A199 R208 S212 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ A 2.20 BS03 5R6 A 1 W64 G65 M72 Y74 K110 E112 H130 D132 A135 W180 F245 L246 W48 G49 M56 Y58 K94 E96 H114 D116 A119 W164 F229 L230 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ B 2.20 BS01 FE B 1 H130 D132 H213 H114 D116 H197 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ B 2.20 BS02 AKG B 1 M72 L114 K116 T127 H130 D132 W148 M161 H207 H213 A215 R224 S228 M56 L98 K100 T111 H114 D116 W132 M145 H191 H197 A199 R208 S212 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ B 2.20 BS03 5R6 B 1 W64 G65 S66 M72 Y74 K110 E112 H130 D132 W180 F245 L246 W48 G49 S50 M56 Y58 K94 E96 H114 D116 W164 F229 L230 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ C 2.20 BS01 FE C 1 H130 D132 H213 H114 D116 H197 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ C 2.20 BS02 AKG C 1 M72 L114 K116 T127 H130 D132 T146 W148 M161 H207 H213 A215 R224 S228 M56 L98 K100 T111 H114 D116 T130 W132 M145 H191 H197 A199 R208 S212 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ C 2.20 BS03 5R6 C 1 W64 G65 S66 M72 Y74 K110 E112 H130 D132 W180 F245 L246 W48 G49 S50 M56 Y58 K94 E96 H114 D116 W164 F229 L230 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ D 2.20 BS01 FE D 1 H130 D132 H213 H114 D116 H197 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ D 2.20 BS02 AKG D 1 M72 L114 K116 T127 H130 D132 W148 M161 H213 A215 R224 S228 M56 L98 K100 T111 H114 D116 W132 M145 H197 A199 R208 S212 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5equ D 2.20 BS03 5R6 D 1 W64 G65 S66 M72 Y74 K110 E112 L114 H130 D132 W180 F245 L246 W48 G49 S50 M56 Y58 K94 E96 L98 H114 D116 W164 F229 L230 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5erl A 2.85 BS01 5R6 A 1 W64 G65 S66 M72 Y74 K110 E112 A128 H130 D132 W180 F245 L246 W48 G49 S50 M56 Y58 K94 E96 A112 H114 D116 W164 F229 L230 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLRR 5erl B 2.85 BS01 5R6 B 1 W64 G65 S66 Y74 K110 E112 H130 D132 W180 F245 W48 G49 S50 Y58 K94 E96 H114 D116 W164 F229 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLR 5erl C 2.85 BS01 5R6 C 1 W64 G65 S66 M72 Y74 K110 E112 H130 D132 W180 F245 L246 W48 G49 S50 M56 Y58 K94 E96 H114 D116 W164 F229 L230 Q9EYI0 27114534 DPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLRR 5erl D 2.85 BS01 5R6 D 1 W64 G65 M72 Y74 K110 E112 L114 H130 D132 W180 F245 W49 G50 M57 Y59 K95 E97 L99 H115 D117 W165 F230 Q9EYI0 27114534 SDPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLAHEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENKEKDASVPTAPHHDAFAFPFSTAGTALTAWVALVDVPVERGCMTFVPGSHLLPDPDTGDEPWAGAFTRPGEIWMPRVTVPLRAGDCTFHHARTVHSAGANSTDEPRLSTSAVYMDATAAYRPTGIAFLDDLPGTGADPLREGAPLTGDRFPLLRR 5f5w A 2.81 BS01 G5A A 1 T33 R58 D61 N69 R70 L71 Y74 Q76 W115 E135 I136 T137 Q138 E156 T158 G160 R163 T33 R58 D61 N69 R70 L71 Y74 Q76 W115 E135 I136 T137 Q138 E156 T158 G160 R163 6.1.1.14 O67081 MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVILKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYGLERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCSHVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFENVG 5f5w B 2.81 BS01 G5A B 1 T33 R58 D61 N69 R70 L71 Y74 Q76 W115 E135 I136 T137 Q138 E156 T158 G160 R163 T33 R58 D61 N69 R70 L71 Y74 Q76 W115 E135 I136 T137 Q138 E156 T158 G160 R163 6.1.1.14 O67081 MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVILKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYGLERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCSHVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFEN 5f5w C 2.81 BS01 G5A C 1 T33 R58 D61 N69 R70 L71 Y74 Q76 W115 E135 I136 T137 Q138 E156 T158 G160 R163 T33 R58 D61 N69 R70 L71 Y74 Q76 W115 E135 I136 T137 Q138 E156 T158 G160 R163 6.1.1.14 O67081 MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVILKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYGLERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCSHVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFEN 5f5w D 2.81 BS01 G5A D 1 T33 R58 D61 N69 R70 L71 Y74 Q76 W115 E135 I136 T137 Q138 E156 T158 G160 R163 T31 R56 D59 N67 R68 L69 Y72 Q74 W113 E133 I134 T135 Q136 E154 T156 G158 R161 6.1.1.14 O67081 FQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVILKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYGLERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCSHVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFE 5f5w E 2.81 BS01 G5A E 1 T33 R58 D61 N69 R70 L71 Y74 Q76 W115 E135 I136 T137 Q138 E156 T158 G160 R163 T31 R56 D59 N67 R68 L69 Y72 Q74 W113 E133 I134 T135 Q136 E154 T156 G158 R161 6.1.1.14 O67081 FQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVILKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYGLERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCSHVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFE 5f9e A 2.00 BS01 5VS A 1 L386 G387 F391 V394 A407 K409 T442 M458 E459 Y460 L461 N509 L511 D522 F664 L13 G14 F18 V21 A34 K36 T69 M85 E86 Y87 L88 N136 L138 D149 F291 2.7.11.13 Q04759 27117263 KLKIEDFELHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNEFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMNPGMERLISHHH 5f9e B 2.00 BS01 5VS B 1 L386 F391 V394 A407 K409 T442 M458 E459 Y460 L461 N509 L511 D522 L12 F17 V20 A33 K35 T68 M84 E85 Y86 L87 N135 L137 D148 2.7.11.13 Q04759 27117263 LKIEDFELHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNEFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREINWEELERKEIDPPFRPKVKNMFRNFSFMNPG 5fc9 A 1.60 BS01 CU A 1 H1043 C1083 H1086 H42 C82 H85 A9A2G4 27120678 DAQIIIPNGNYDVTGAGFYSPLNLEIPVGTTVTWTNDDSVPHNIQSIDVNGKVIQLFNSPPLNTGDRFEHVFEEEGVYKYYCSFHPWRVGLVTVS 5fc9 B 1.60 BS01 CU B 1 H2043 C2083 H2086 H42 C82 H85 A9A2G4 27120678 DAQIIIPNGNYDVTGAGFYSPLNLEIPVGTTVTWTNDDSVPHNIQSIDVNGKVIQLFNSPPLNTGDRFEHVFEEEGVYKYYCSFHPWRVGLVTVS 5fc9 C 1.60 BS01 CU C 1 H3043 C3083 H3086 H42 C82 H85 A9A2G4 27120678 DAQIIIPNGNYDVTGAGFYSPLNLEIPVGTTVTWTNDDSVPHNIQSIDVNGKVIQLFNSPPLNTGDRFEHVFEEEGVYKYYCSFHPWRVGLVTVS 5fc9 D 1.60 BS01 CU D 1 H4043 C4083 H4086 H42 C82 H85 A9A2G4 27120678 DAQIIIPNGNYDVTGAGFYSPLNLEIPVGTTVTWTNDDSVPHNIQSIDVNGKVIQLFNSPPLNTGDRFEHVFEEEGVYKYYCSFHPWRVGLVTVS 5fi2 A 2.50 BS01 5XX A 1 K319 L320 F321 L322 Y393 K184 L185 F186 L187 Y258 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5fi2 D 2.50 BS01 5XX D 1 K319 L320 F321 L322 N323 E324 Y393 K184 L185 F186 L187 N188 E189 Y258 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5fi6 A 2.52 BS01 5XY A 1 R316 F317 K319 L320 F321 L322 N323 E324 Y393 R181 F182 K184 L185 F186 L187 N188 E189 Y258 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5fi6 B 2.52 BS01 5XY A 1 K319 L320 F321 L322 N323 E324 Y393 K184 L185 F186 L187 N188 E189 Y258 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5fi6 C 2.52 BS01 5XY C 1 K319 L320 F321 L322 N323 E324 Y393 K184 L185 F186 L187 N188 E189 Y258 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5fi6 D 2.52 BS01 5XY C 1 K319 L320 F321 L322 N323 E324 Y393 K184 L185 F186 L187 N188 E189 Y258 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5fi7 A 2.50 BS01 5XZ A 1 K319 L320 F321 L322 N323 E324 Y393 K184 L185 F186 L187 N188 E189 Y258 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5fi7 C 2.50 BS01 5XZ C 1 K319 L320 F321 L322 N323 E324 D326 Y393 K397 K184 L185 F186 L187 N188 E189 D191 Y258 K262 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5fjs A 2.60 BS01 CA A 1 D575 D577 D579 I581 P582 D583 D505 D507 D509 I511 P512 D513 3.2.1.21 F6BL85 27115290 HKIDIPDSAWTIGIGEKFKNAGHPNVKYPMIDDSYVQGAPLGGFGAGTIGRTYNGGFSRWHLEIGKNKYTTVYANQFSVFVAQVLYAGEPNGYLSSWKWDYPKESGMYYALYPNSWYTYTNKDLPVQLAVKQFSPIIPYNYKETSYPVAVFKWTAYNVDVSMFTWQNMIGFFVNSGNFNKIIKDDSEIVAAVMGNSNDNEEWNGEYSIGVKKVPGVDISYKAKFVTTGDGSDLWHEFDNKDDETPTKQDGIGSAIAVNFKLQPQTIEVPFALSWDLPIMKFGGGDKWYKMYTKYFGKNGKNSFAILKEALNNYQKWEKMIDDWQKPILSNKSKPDWYKTALFNELYYLADGGTAWENGKVGRTNNMFGLLECFDYNYYETLDVRFYGSFPLVMLWPDIEKQVMRQFADTINVQDSSEFKVGSNGAMAVKKVQGMIPHDLGSSYALPWIKINAYDWQNPNIWKDLNSKYVLLVYRDYVLTGKTDKEFLKYTWKSVKTALDKLKEMDKDNDGIPDNEGIPDQTYDTWSMKGTSAYCGSLWLAALKAAQEIGKVLKDNEAYIKYNEWYKIAQQNFEKELWNGEYYNFDTESDHKDSIMADQLAGQWYADILRLGDILPKDHVQKALKKIYEFNVMKFENGKMGAVNGMRPDGIVDESDIQAQEVWTGVTYALASFMKYRGMTEEAYNTAYGVYKMTYDKSGKGYWFRTPEAWTKDGNYRASMYMRPLSIWSMEVNY 5fjs B 2.60 BS01 CA B 1 D575 D577 D579 I581 P582 D583 D474 D476 D478 I480 P481 D482 3.2.1.21 F6BL85 27115290 SHKIDIPDSAWTIGIGEKFKNAGHPNVKYPMIDDSYVQGAPLGGFGAGTIGRTYNGGFSRWHLEIGKNKYTTVYANQFSVQVLYAGGYLSSWKWDYPKESGMYYALYPNSWYTYTNVQLAVKQFSPIIPYNYKETSYPVAVFKWTAYSIMFTWQNMIGFNSGNFDSEIVVMGNISNWNGEYSIGVKKVPGKAKFVTDGSDLWEFSKNDNKDDEPTKQGIGSAIAVNFKLQPGQTIEVPFALSWDLPIMKFGGGDKWYKMYTKYFGKNGKNSFAILKEALNNYQKWEKMIDDWQKPILSNKSKPDWYKTALFNELYYLADGGTAWENGKVGETNNMFGLLECFDYNYYETLDVRFYGSFPLVMLWPDIEKQVMRQFADTINVQDSSEFKVGSNGAMAVKKVQGMIPHDLGSSYALPWIKINAYDWQNPNIWKDLNSKYVLLVYRDYVLTGKTDKEFLKYTWKSVKTALDKLKEMDKDNDGIPDNEGIPDQTYDTWSMKGTSAYCGSLWLAALKAAQEIGKVLKDNEAYIKYNEWYKIAQQNFEKELWNGEYYNFDTESDHKDSIMADQLAGQWYADILRLGDILPKDHVQKALKKIYEFNVMKFENGKMGAVNGMRPDGIVDESDIQAQEVWTGVTYALASFMKYRGMTEEAYNTAYGVYKMTYDKSGKGYWFRTPEAWTKDGNYRASMYMRPLSIWSMEVNY 5fpp A 2.40 BS01 HI6 A 1 D74 Y124 S203 W286 R296 F297 S298 Y337 F338 Y341 D74 Y124 S203 W279 R289 F290 S291 Y330 F331 Y334 3.1.1.7 P21836 27140636 EGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATATEAP 5fpp B 2.40 BS01 HI6 B 1 W86 Y124 E202 S203 F295 F297 S298 Y337 F338 Y341 W82 Y120 E198 S199 F284 F286 S287 Y326 F327 Y330 3.1.1.7 P21836 27140636 DPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATA 5fs6 A 1.90 BS01 FAD A 1 G138 G139 G140 T141 A142 V162 E164 D165 R172 P173 S176 K177 K232 V233 A259 T260 G261 F284 R285 K286 L311 G437 D438 E453 H454 H455 A458 F482 W483 G12 G13 G14 T15 A16 V36 E38 D39 R46 P47 S50 K51 K106 V107 A133 T134 G135 F158 R159 K160 L185 G311 D312 E327 H328 H329 A332 F356 W357 1.1.1.- O95831 KAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMLKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHEDLVPR 5fs6 B 1.90 BS01 FAD B 1 G138 G139 G140 T141 A142 V162 E164 D165 R172 P173 S176 K177 K231 K232 V233 A259 T260 G261 F284 R285 K286 L311 G437 D438 E453 H454 H455 A458 F482 W483 G13 G14 G15 T16 A17 V37 E39 D40 R47 P48 S51 K52 K106 K107 V108 A134 T135 G136 F159 R160 K161 L186 G312 D313 E328 H329 H330 A333 F357 W358 1.1.1.- O95831 DKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMLKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHE 5fs7 A 1.85 BS01 FAD A 1 G138 G139 G140 T141 A142 V162 E164 D165 R172 P173 S176 K177 K231 K232 V233 A259 T260 G261 F284 R285 K286 L311 N403 G437 D438 E453 H454 H455 A458 F482 W483 G13 G14 G15 T16 A17 V37 E39 D40 R47 P48 S51 K52 K106 K107 V108 A134 T135 G136 F159 R160 K161 L186 N278 G312 D313 E328 H329 H330 A333 F357 W358 1.1.1.- O95831 DKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGSTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHE 5fs7 B 1.85 BS01 FAD B 1 G138 G139 G140 T141 A142 V162 E164 D165 R172 P173 S176 K177 K231 K232 V233 A259 T260 G261 F284 R285 K286 L311 N403 G437 D438 E453 H454 H455 A458 F482 W483 G12 G13 G14 T15 A16 V36 E38 D39 R46 P47 S50 K51 K105 K106 V107 A133 T134 G135 F158 R159 K160 L185 N277 G311 D312 E327 H328 H329 A332 F356 W357 1.1.1.- O95831 KAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGSTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED 5fs8 A 1.40 BS01 FAD A 1 G138 G139 G140 T141 A142 V162 E164 D165 R172 P173 S176 K177 K231 K232 V233 A259 T260 G261 F284 R285 K286 L311 N403 G437 D438 E453 H454 H455 A458 F482 W483 G14 G15 G16 T17 A18 V38 E40 D41 R48 P49 S52 K53 K107 K108 V109 A135 T136 G137 F160 R161 K162 L187 N279 G313 D314 E329 H330 H331 A334 F358 W359 1.1.1.- O95831 QDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGEGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESRASEITIPPDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIH 5fs9 A 1.75 BS01 FAD A 1 G138 G139 G140 T141 A142 V162 E164 R172 P173 S176 K177 K231 K232 V233 A259 T260 G261 F284 R285 L311 G437 D438 E453 H454 H455 A458 F482 W483 G13 G14 G15 T16 A17 V37 E39 R47 P48 S51 K52 K106 K107 V108 A134 T135 G136 F159 R160 L186 G312 D313 E328 H329 H330 A333 F357 W358 1.1.1.- O95831 DKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKENMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHE 5fs9 B 1.75 BS01 FAD B 1 G138 G139 G140 T141 A142 V162 E164 D165 R172 P173 S176 K177 K231 K232 V233 A259 T260 G261 F284 R285 L311 G437 D438 E453 H454 H455 A458 F482 W483 G13 G14 G15 T16 A17 V37 E39 D40 R47 P48 S51 K52 K106 K107 V108 A134 T135 G136 F159 R160 L186 G312 D313 E328 H329 H330 A333 F357 W358 1.1.1.- O95831 DKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKENMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHEDLVPR 5g2x C 3.80 BS01 NUC B 1 R378 L380 F449 N453 Y457 Y461 D484 E494 I495 K496 G498 K499 R501 Y529 N532 N536 R314 L316 F385 N389 Y393 Y397 D420 E430 I431 K432 G434 K435 R437 Y443 N446 N450 2.7.7.49,3.1.-.- P0A3U0 27136327 TMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTADGFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILESIYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGDIKGCFDNIDHVTLIGLINLKIKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKFDRESPERITPEKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPARFLGYDIRVVKKRTLNGSVELLIPLQDKIRQFIFDKKIAIQKKDSSWFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASKHKGTLSKTISMFKDGSGSWGIPYEIKQGKQRRVLYGYARNTLENRLKAKCCELCGTSDENTSYEIHHVNRKTLVVCFHCH 5h9l A 1.37 BS01 EAH A 1 W31 Y48 L56 F58 K61 F81 F91 S93 M95 L108 R110 Y114 K120 N122 W29 Y46 L54 F56 K59 F79 F89 S91 M93 L106 R108 Y112 K118 N120 Q7YT09 27124118 VTSIPTGCNALSGKIMSGFDANRFFTGDWYLTHSRDSEVPVRCEKYQTGSNLQLNFNGKNGDVKCSGSTVSGNQGFYSFQCTTTSGGSFTSYMAVVETDYANYALLYRCGLYGSTTPKDNFLLFNRQSSGEIPAGLSTKLNQLELTSLNKLGCS 5h9l A 1.37 BS02 GSH A 1 G60 K61 F91 Y114 G58 K59 F89 Y112 Q7YT09 27124118 VTSIPTGCNALSGKIMSGFDANRFFTGDWYLTHSRDSEVPVRCEKYQTGSNLQLNFNGKNGDVKCSGSTVSGNQGFYSFQCTTTSGGSFTSYMAVVETDYANYALLYRCGLYGSTTPKDNFLLFNRQSSGEIPAGLSTKLNQLELTSLNKLGCS 5h9n A 1.28 BS01 LTX A 1 W31 L56 F58 G60 K61 F91 S93 M95 R110 A114 G115 N122 F126 W29 L54 F56 G58 K59 F89 S91 M93 R108 A112 G113 N120 F124 Q7YT09 27124118 VTSIPTGCNALSGKIMSGFDANRFFTGDWYLTHSRDSEVPVRCEKYQTGSNLQLNFNGKNGDVKCSGSTVSGNQGFYSFQCTTTSGGSFTSYMAVVETDYANYALLYRCGLAGSTTPKDNFLLFNRQSSGEIPAGLSTKLNQLELTSLNKLGCS 5ha0 A 1.44 BS01 LTD A 1 F26 L56 F58 G60 K61 C83 F91 S93 M95 R110 Y114 N122 F126 F26 L56 F58 G60 K61 C83 F91 S93 M95 R110 Y114 N122 F126 Q7YT09 27124118 AEVTSIPTGCNALSGKIMSGFDANRFFTGDWYLTHSRDSEVPVRCEKYQTGSNLQLNFNGKNGDVKCSGSTVSGNQGFYSFQCTTTSGGSFTSYMAVVETDYANYALLYRCGLYGSTTPKDNFLLFNRQSSGEIPAGLSTKLNQLELTSLNKLGCS 5hae A 2.00 BS01 EAH A 1 F26 L56 F58 K61 F81 F91 S93 M95 L108 R110 Y114 N122 F126 F25 L55 F57 K60 F80 F90 S92 M94 L107 R109 Y113 N121 F125 Q7YT09 27124118 EVTSIPTGCNALSGKIMSGFDANRFFTGDWYLTHSRDSEVPVRCEKYQTGSNLQLNFNGKNGDVKCSGSTVSGNQGFYSFQCTTTSGGSFTSYMAVVETDYANYALLYRCGLYGSTTPKDNFLLFNRQSSGEIPAGLSTKLNQLELTSLNKLGCS 5hae A 2.00 BS02 GSH A 1 G60 K61 V65 F91 Y114 G59 K60 V64 F90 Y113 Q7YT09 27124118 EVTSIPTGCNALSGKIMSGFDANRFFTGDWYLTHSRDSEVPVRCEKYQTGSNLQLNFNGKNGDVKCSGSTVSGNQGFYSFQCTTTSGGSFTSYMAVVETDYANYALLYRCGLYGSTTPKDNFLLFNRQSSGEIPAGLSTKLNQLELTSLNKLGCS 5he0 A 2.56 BS01 453 A 1 I197 G198 R199 G200 G201 F202 G203 V205 A218 L222 L235 E239 V255 L271 D272 M274 A321 N322 L324 S334 D335 G337 I168 G169 R170 G171 G172 F173 G174 V176 A189 L193 L206 E210 V226 L242 D243 M245 A292 N293 L295 S305 D306 G308 2.7.11.15 P21146 27050625 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5he1 A 3.15 BS01 ZS2 A 1 G198 R199 G200 F202 G203 E204 V205 A218 L222 L235 E239 V255 D272 M274 A321 N322 L324 S334 D335 G170 R171 G172 F174 G175 E176 V177 A190 L194 L207 E211 V227 D244 M246 A293 N294 L296 S306 D307 2.7.11.15 P25098 27050625 SKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5he1 A 3.15 BS02 MG A 1 H348 E360 V361 Q363 V366 Y368 H320 E332 V333 Q335 V338 Y340 2.7.11.15 P25098 27050625 SKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5he2 A 2.79 BS01 F0S A 1 I197 R199 G200 G201 F202 G203 V205 A218 L222 L235 E239 V255 L271 D272 M274 N322 L324 S334 D335 G337 L338 I168 R170 G171 G172 F173 G174 V176 A189 L193 L206 E210 V226 L242 D243 M245 N293 L295 S305 D306 G308 L309 2.7.11.15 P21146 27050625 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5he3 A 2.74 BS01 MG A 1 H348 E360 V361 Q363 V366 Y368 H319 E331 V332 Q334 V337 Y339 2.7.11.15 P21146 27050625 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRS 5he3 A 2.74 BS02 FF1 A 1 I197 G198 R199 G200 G201 F202 G203 V205 A218 L222 K230 V255 L271 D272 L273 M274 N322 L324 S334 D335 I168 G169 R170 G171 G172 F173 G174 V176 A189 L193 K201 V226 L242 D243 L244 M245 N293 L295 S305 D306 2.7.11.15 P21146 27050625 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRS 5htb A 1.70 BS01 III C 1 V494 N522 A587 N588 H651 N654 D687 T689 L690 D707 D709 Q718 Y722 V24 N52 A117 N118 H181 N184 D217 T219 L220 D237 D239 Q248 Y252 2.7.11.1 Q8TF76 27139824 GPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 5htb A 1.70 BS02 6L5 C 1 I490 G491 E492 G493 V494 F495 G496 V498 A509 K511 I557 E606 F607 G608 G609 D611 G653 L656 I686 T689 I20 G21 E22 G23 V24 F25 G26 V28 A39 K41 I87 E136 F137 G138 G139 D141 G183 L186 I216 T219 2.7.11.1 Q8TF76 27139824 GPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 5hwo A 1.48 BS01 HMG A 1 D31 A33 K34 G38 E83 A114 C115 Y149 A154 G155 T158 F192 V203 G205 H206 S208 I209 Y212 H250 P252 F253 K259 N309 Y340 G341 S342 D31 A33 K34 G38 E83 A114 C115 Y149 A154 G155 T158 F192 V203 G205 H206 S208 I209 Y212 H250 P252 F253 K259 N309 Y340 G341 S342 2.3.3.10 Q1D4I1 27124816 MKKRVGIEALAVAVPSRYVDIEDLARARGVDPAKYTAGLGAREMAVTDPGEDTVALAATAAARLIRQQDVDPSRIGMLVVGTETGIDHSKPVASHVQGLLKLPRTMRTYDTQHACYGGTAGLMAAVEWIASGAGAGKVAVVVCSDIARYGLNTAGEPTQGGGAVALLVSEQPDLLAMDVGLNGVCSMDVYDFWRPVGRREALVDGHYSITCYLEALSGAYRGWREKALAAGLVRWSDALPGEQLARIAYHVPFCKMARKAHTQLRLCDLEDAADAAASTPESREAQAKSAASYDAQVATSLGLNSRIGNVYTASLYLALAGLLQHEAGALAGQRIGLLSYGSGCAAEFYSGTVGEKAAERMAKADLEAVLARRERVSIEEYERLMKLPADAPEAVAPSPGAFRLTEIRDHRRQYAEGN 5hwp A 2.20 BS01 COA A 1 D31 A33 K34 G38 L39 Y149 A154 G155 T158 V203 G205 H206 S208 I209 P252 F253 K259 D29 A31 K32 G36 L37 Y147 A152 G153 T156 V201 G203 H204 S206 I207 P250 F251 K257 2.3.3.10 Q1D4I1 27124816 KRVGIEALAVAVPSRYVDIEDLARARGVDPAKYTAGLGAREMAVTDPGEDTVALAATAAARLIRQQDVDPSRIGMLVVGTETGIDHSKPVASHVQGLLKLPRTMRTYDTQHACYGGTAGLMAAVEWIASGAGAGKVAVVVCSDIARYGLNTAGEPTQGGGAVALLVSEQPDLLAMDVGLNGVCSMDVYDFWRPVGRREALVDGHYSITCYLEALSGAYRGWREKALAAGLVRWSDALPGEQLARIAYHVPFCKMARKAHTQLRLCDLEDAADAAASTPESREAQAKSAASYDAQVATSLGLNSRIGNVYTASLYLALAGLLQHEAGALAGQRIGLLSYGSGCAAEFYSGTVGEKAAERMAKADLEAVLARRERVSIEEYERLMKLPADAPEAVAPSPGAFRLTEIRDHRRQYAEG 5hwq A 1.50 BS01 CAA A 1 D31 A33 K34 G38 C115 Y149 A154 G155 T158 F192 V203 G205 H206 S208 I209 Y212 H250 P252 F253 K255 K259 N309 Y340 S342 D31 A33 K34 G38 C115 Y149 A154 G155 T158 F192 V203 G205 H206 S208 I209 Y212 H250 P252 F253 K255 K259 N309 Y340 S342 2.3.3.10 Q1D4I1 27124816 MKKRVGIEALAVAVPSRYVDIEDLARARGVDPAKYTAGLGAREMAVTDPGEDTVALAATAAARLIRQQDVDPSRIGMLVVGTETGIDHSKPVASHVQGLLKLPRTMRTYDTQHACYGGTAGLMAAVEWIASGAGAGKVAVVVCSDIARYGLNTAGEPTQGGGAVALLVSEQPDLLAMDVGLNGVCSMDVYDFWRPVGRREALVDGHYSITCYLEALSGAYRGWREKALAAGLVRWSDALPGEQLARIAYHVPFCKMARKAHTQLRLCDLEDAADAAASTPESREAQAKSAASYDAQVATSLGLNSRIGNVYTASLYLALAGLLQHEAGALAGQRIGLLSYGSGCAAEFYSGTVGEKAAERMAKADLEAVLARRERVSIEEYERLMKLPADAPEAVAPSPGAFRLTEIRDHRRQYAEGN 5hwr A 1.50 BS01 COA A 1 D31 A33 K34 G38 Y149 A154 G155 T158 V203 G205 H206 S208 I209 Y212 P252 F253 M256 K259 D30 A32 K33 G37 Y148 A153 G154 T157 V202 G204 H205 S207 I208 Y211 P251 F252 M255 K258 2.3.3.10 Q1D4I1 27124816 KKRVGIEALAVAVPSRYVDIEDLARARGVDPAKYTAGLGAREMAVTDPGEDTVALAATAAARLIRQQDVDPSRIGMLVVGTETGIDHSKPVASHVQGLLKLPRTMRTYDTQHACYGGTAGLMAAVEWIASGAGAGKVAVVVCSDIARYGLNTAGEPTQGGGAVALLVSEQPDLLAMDVGLNGVCSMDVYDFWRPVGRREALVDGHYSITCYLEALSGAYRGWREKALAAGLVRWSDALPGEQLARIAYHVPFCKMARKAHTQLRLCDLEDAADAAASTPESREAQAKSAASYDAQVATSLGLNSRIGNVYTASLYLALAGLLQHEAGALAGQRIGLLSYGSGCAAEFYSGTVGEKAAERMAKADLEAVLARRERVSIEEYERLMKLPADAPEAVAPSPGAFRLTEIRDHRRQYAEGN 5hwx A 2.40 BS01 NA A 1 T50 S51 P53 E54 T209 S210 P212 E213 T50 S51 P53 E54 T202 S203 P205 E206 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5hwx A 2.40 BS02 NA A 2 M46 A47 T50 S51 E213 S236 M46 A47 T50 S51 E206 S229 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5hxc A 2.10 BS01 CA A 1 I118 D121 G122 F123 D127 I118 D121 G122 F123 D127 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxc A 2.10 BS02 NA A 1 A47 T50 S51 E213 S236 A47 T50 S51 E209 S232 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxc A 2.10 BS03 NA A 2 E54 N73 S77 A206 T209 S210 E54 N73 S77 A202 T205 S206 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxc A 2.10 BS04 NA A 3 T50 S51 P53 E54 T209 S210 P212 E213 T50 S51 P53 E54 T205 S206 P208 E209 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxc A 2.10 BS05 MYC A 1 V117 I120 N258 V117 I120 N254 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxc A 2.10 BS06 MYC A 2 V107 F111 L134 V107 F111 L134 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxc A 2.10 BS07 MYC A 3 T44 V45 I48 V143 T44 V45 I48 V143 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxc A 2.10 BS08 MYC A 4 Y60 F202 Y60 F198 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxe A 2.29 BS01 NA A 1 I118 G119 D121 G122 F123 D127 I118 G119 D121 G122 F123 D127 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxe A 2.29 BS02 NA A 2 A47 T50 S51 E213 S236 A47 T50 S51 E206 S229 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxe A 2.29 BS03 NA A 3 T50 S51 P53 E54 T209 S210 P212 E213 T50 S51 P53 E54 T202 S203 P205 E206 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxe A 2.29 BS04 NA A 4 E54 N73 S77 A206 T209 S210 E54 N73 S77 A199 T202 S203 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hxh A 2.80 BS01 CA A 1 I118 D121 G122 D127 I118 D121 G122 D127 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSDKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLR 5hxh B 2.80 BS01 CA B 1 I118 D121 G122 D127 I118 D121 G122 D127 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSANPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLR 5hxr A 2.46 BS01 CA A 1 I118 D121 G122 D127 I118 D121 G122 D127 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLR 5hxr A 2.46 BS02 CA A 2 T50 S51 E54 T209 S210 E213 T50 S51 E54 T202 S203 E206 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLR 5hya A 1.90 BS01 NA A 1 A47 T50 S51 E213 S236 A47 T50 S51 E206 S229 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hya A 1.90 BS02 NA A 2 T50 S51 P53 E54 T209 S210 P212 E213 T50 S51 P53 E54 T202 S203 P205 E206 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hya A 1.90 BS03 NA A 3 E54 S77 A206 T209 S210 E54 S77 A199 T202 S203 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hya A 1.90 BS04 CA A 1 I118 D121 G122 F123 D127 I118 D121 G122 F123 D127 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG 5hyn A 2.95 BS01 III D 1 Q648 D652 G655 D659 S664 L666 F667 N668 A697 F724 Y726 R727 Y728 Q489 D493 G496 D500 S505 L507 F508 N509 A538 F565 Y567 R568 Y569 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS02 III E 1 I131 D136 D140 G159 D160 I122 D127 D131 G150 D151 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS03 ZN A 1 C286 C289 C294 H297 C239 C242 C247 H250 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS04 ZN A 2 C320 C324 C452 C463 C273 C277 C329 C340 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS05 ZN A 3 C530 C543 C549 C553 C371 C384 C390 C394 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS06 ZN A 4 C523 H525 C530 C534 C364 H366 C371 C375 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS07 ZN A 5 C523 C536 C543 C547 C364 C377 C384 C388 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS08 ZN A 6 C560 C566 C580 C588 C601 C401 C407 C421 C429 C442 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS09 ZN A 7 C560 C573 C580 C585 C401 C414 C421 C426 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS10 ZN A 8 C560 C562 C566 C571 C401 C403 C407 C412 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn A 2.95 BS11 SAH A 1 V621 A622 G623 W624 M662 C663 S664 F665 F686 A687 N688 H689 Y726 L734 Y736 V462 A463 G464 W465 M503 C504 S505 F506 F527 A528 N529 H530 Y567 L575 Y577 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNESRPPRSDKIFEAISSMFPDKGTAEELKEKYKELTEPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIE 5hyn B 2.95 BS01 III E 1 Y148 R306 N307 C324 D362 I363 W364 Y365 R414 Y72 R230 N231 C248 D286 I287 W288 Y289 R338 O75530 27121947 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR 5hyn F 2.95 BS01 III I 1 Q648 A651 D652 G655 D659 S664 L666 F667 N668 A697 V699 F724 Y726 R727 Y728 Q477 A480 D481 G484 D488 S493 L495 F496 N497 A526 V528 F553 Y555 R556 Y557 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS02 III J 1 Y133 D136 E137 D140 Y124 D127 E128 D131 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS03 ZN F 1 C286 C289 C294 H297 C230 C233 C238 H241 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS04 ZN F 2 C320 C324 C452 C463 C264 C268 C318 C329 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS05 ZN F 3 C530 C543 C549 C553 C359 C372 C378 C382 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS06 ZN F 4 C523 H525 C530 C534 C352 H354 C359 C363 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS07 ZN F 5 C523 C536 C543 C547 C352 C365 C372 C376 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS08 ZN F 6 C566 C580 C588 C601 C395 C409 C417 C430 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS09 ZN F 7 C560 C573 C580 C585 C389 C402 C409 C414 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS10 ZN F 8 C560 C562 C566 C571 C389 C391 C395 C400 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn F 2.95 BS11 SAH F 1 V621 A622 G623 W624 M662 C663 S664 F665 F686 N688 H689 Y726 A733 L734 Y736 V450 A451 G452 W453 M491 C492 S493 F494 F515 N517 H518 Y555 A562 L563 Y565 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn G 2.95 BS01 III J 1 F97 Y148 N307 Y308 C324 D362 I363 W364 Y365 R414 F21 Y72 N231 Y232 C248 D286 I287 W288 Y289 R338 O75530 27121947 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR 5hyn K 2.95 BS01 III O 1 N152 Q648 D652 G655 D659 S664 L666 F667 N668 A697 F724 Y726 R727 Y728 N143 Q478 D482 G485 D489 S494 L496 F497 N498 A527 F554 Y556 R557 Y558 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS02 III P 1 I131 Y133 D136 E137 D140 I122 Y124 D127 E128 D131 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS03 ZN K 1 C286 C289 C294 H297 C228 C231 C236 H239 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS04 ZN K 2 C320 C324 C452 C463 C262 C266 C317 C328 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS05 ZN K 3 C530 C543 C549 C553 C360 C373 C379 C383 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS06 ZN K 4 C523 H525 C530 C534 C353 H355 C360 C364 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS07 ZN K 5 C523 C536 C543 C547 C353 C366 C373 C377 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS08 ZN K 6 C566 C580 C588 C601 C396 C410 C418 C431 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS09 ZN K 7 C560 C573 C580 C585 C390 C403 C410 C415 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS10 ZN K 8 C560 C562 C566 C571 C390 C392 C396 C401 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn K 2.95 BS11 SAH K 1 V621 A622 G623 W624 M662 C663 S664 F665 R685 F686 N688 H689 Y726 V451 A452 G453 W454 M492 C493 S494 F495 R515 F516 N518 H519 Y556 2.1.1.43 Q15910 27121947 KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYPSDKIFEAISSMFPDKGTAEELKEKYKELCTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQAD 5hyn L 2.95 BS01 III P 1 F97 Y148 N307 C324 D362 I363 W364 Y365 R414 F21 Y72 N231 C248 D286 I287 W288 Y289 R338 O75530 27121947 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR 5hyn Q 2.95 BS01 III T 1 Y641 Q648 A651 D652 G655 L666 F667 N668 A697 V699 F724 Y726 R727 Y728 Y467 Q474 A477 D478 G481 L492 F493 N494 A523 V525 F550 Y552 R553 Y554 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS02 III U 1 I131 Y133 D136 I120 Y122 D125 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS03 ZN Q 1 C286 C289 C294 H297 C227 C230 C235 H238 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS04 ZN Q 2 C320 C452 C463 C261 C314 C325 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS05 ZN Q 3 C530 C543 C549 C553 C356 C369 C375 C379 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS06 ZN Q 4 C523 H525 C530 C534 C349 H351 C356 C360 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS07 ZN Q 5 C523 C536 C543 C547 C349 C362 C369 C373 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS08 ZN Q 6 C566 C580 C588 C601 C392 C406 C414 C427 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS09 ZN Q 7 C560 C573 C580 C585 C386 C399 C406 C411 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS10 ZN Q 8 C560 C562 C566 C571 C386 C388 C392 C397 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn Q 2.95 BS11 SAH Q 1 V621 A622 G623 W624 M662 C663 S664 F665 F686 N688 H689 Y726 A733 L734 K735 V447 A448 G449 W450 M488 C489 S490 F491 F512 N514 H515 Y552 A559 L560 K561 2.1.1.43 Q15910 27121947 PVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQPSDKIFEAISSMFPDKGTAEELKEKYKELTECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIANHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGI 5hyn R 2.95 BS01 III U 1 F97 Y148 N307 Y308 C324 D362 I363 W364 Y365 R414 D430 F21 Y72 N231 Y232 C248 D286 I287 W288 Y289 R338 D354 O75530 27121947 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR 5i90 A 1.22 BS01 PLP A 1 S121 T122 T123 H148 T201 S205 D238 V240 H241 H263 K264 S84 T85 T86 H111 T164 S168 D201 V203 H204 H226 K227 G3XCY5 NKWKALRQQFDLDPQYLHFANFLLTSHPRPVREAIERLRVRFDRNPGEAVDWHREEIWKYEDEARAWAGRYFAVQPGQVALTGSTTDGLAAIYGGLLVQPGKEILTSSHEHYSTYTTLEYRHKRMGTQVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDRIIYVVDGVHGFGVEDVSFADFDCDYFIAGTHKWLFGPRGTGVIIARSEQLQEHLVPSIPTFSRADNFGTLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIHQLNAYLKQRLGEHPKVRLVTPTSPELSSGFTFFRVEGRDCEAVAKHLMAHRVISDAVDRDVGPVVRLAPSLLNDEAEIDRVLEILAPQLA 5i90 A 1.22 BS02 PLP B 1 G307 Y308 G270 Y271 G3XCY5 NKWKALRQQFDLDPQYLHFANFLLTSHPRPVREAIERLRVRFDRNPGEAVDWHREEIWKYEDEARAWAGRYFAVQPGQVALTGSTTDGLAAIYGGLLVQPGKEILTSSHEHYSTYTTLEYRHKRMGTQVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDRIIYVVDGVHGFGVEDVSFADFDCDYFIAGTHKWLFGPRGTGVIIARSEQLQEHLVPSIPTFSRADNFGTLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIHQLNAYLKQRLGEHPKVRLVTPTSPELSSGFTFFRVEGRDCEAVAKHLMAHRVISDAVDRDVGPVVRLAPSLLNDEAEIDRVLEILAPQLA 5i90 B 1.22 BS01 PLP A 1 G307 Y308 G270 Y271 G3XCY5 NKWKALRQQFDLDPQYLHFANFLLTSHPRPVREAIERLRVRFDRNPGEAVDWHREEIWKYEDEARAWAGRYFAVQPGQVALTGSTTDGLAAIYGGLLVQPGKEILTSSHEHYSTYTTLEYRHKRMGTQVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDRIIYVVDGVHGFGVEDVSFADFDCDYFIAGTHKWLFGPRGTGVIIARSEQLQEHLVPSIPTFSRADNFGTLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIHQLNAYLKQRLGEHPKVRLVTPTSPELSSGFTFFRVEGRDCEAVAKHLMAHRVISDAVDRDVGPVVRLAPSLLNDEAEIDRVLEILAPQLA 5i90 B 1.22 BS02 PLP B 1 S121 T122 T123 H148 T201 S205 D238 V240 H241 H263 K264 S84 T85 T86 H111 T164 S168 D201 V203 H204 H226 K227 G3XCY5 NKWKALRQQFDLDPQYLHFANFLLTSHPRPVREAIERLRVRFDRNPGEAVDWHREEIWKYEDEARAWAGRYFAVQPGQVALTGSTTDGLAAIYGGLLVQPGKEILTSSHEHYSTYTTLEYRHKRMGTQVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDRIIYVVDGVHGFGVEDVSFADFDCDYFIAGTHKWLFGPRGTGVIIARSEQLQEHLVPSIPTFSRADNFGTLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIHQLNAYLKQRLGEHPKVRLVTPTSPELSSGFTFFRVEGRDCEAVAKHLMAHRVISDAVDRDVGPVVRLAPSLLNDEAEIDRVLEILAPQLA 5i94 A 2.98 BS01 69V A 1 R316 K319 L320 F321 L322 N323 E324 D326 Y393 R181 K184 L185 F186 L187 N188 E189 D191 Y258 3.5.1.2 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTADGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5i94 B 2.98 BS01 69V B 1 K319 L320 F321 L322 N323 Y393 K184 L185 F186 L187 N188 Y258 3.5.1.2 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTADGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5i94 C 2.98 BS01 69V B 1 K319 L320 F321 L322 N323 Y393 K184 L185 F186 L187 N188 Y258 3.5.1.2 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTADGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5i94 D 2.98 BS01 69V A 1 K319 L320 F321 L322 N323 E324 Y393 K184 L185 F186 L187 N188 E189 Y258 3.5.1.2 O94925 26988803 PSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTADGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREG 5icn A 3.30 BS01 I6P A 1 K305 Y327 Y328 K331 K133 Y155 Y156 K159 Q13330 27109927 GEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQK 5icn B 3.30 BS01 III C 1 Q26 G27 H28 E98 D99 P101 H140 H141 G149 F150 D176 H178 F205 D264 G301 Y303 Q19 G20 H21 E91 D92 P94 H133 H134 G142 F143 D169 H171 F198 D257 G294 Y296 3.5.1.98 Q13547 27109927 RRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHA 5icn B 3.30 BS02 I6P A 1 G27 K31 R270 I305 G20 K24 R263 I298 3.5.1.98 Q13547 27109927 RRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHA 5icn B 3.30 BS03 ZN B 1 D176 H178 D264 D169 H171 D257 3.5.1.98 Q13547 27109927 RRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHA 5id7 A 2.26 BS01 6A4 A 1 S342 V344 L345 R348 P384 L387 N391 Y411 M446 A449 E450 L453 L457 L460 R485 F488 S340 V342 L343 R346 P382 L385 N389 Y409 M444 A447 E448 L451 L455 L458 R483 F486 P02768 27129297 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG 5id7 A 2.26 BS02 6A4 A 2 Y401 F502 F507 F509 K525 A528 L529 L532 H535 V547 F551 A552 S579 Q580 Y399 F500 F505 F507 K523 A526 L527 L530 H533 V545 F549 A550 S577 Q578 P02768 27129297 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG 5id7 A 2.26 BS03 6A4 A 3 K199 S202 F206 F211 W214 L238 H242 V344 E450 S454 L457 L481 R484 R485 K197 S200 F204 F209 W212 L236 H240 V342 E448 S452 L455 L479 R482 R483 P02768 27129297 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG 5id7 B 2.26 BS01 6A4 B 1 S342 V344 L345 R348 P384 L387 Y411 M446 A449 E450 L453 L457 R485 F488 S340 V342 L343 R346 P382 L385 Y409 M444 A447 E448 L451 L455 R483 F486 P02768 27129297 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG 5id7 B 2.26 BS02 6A4 B 2 Y401 N405 F507 K525 L529 L532 H535 K536 F551 A552 S579 Q580 L583 Y399 N403 F505 K523 L527 L530 H533 K534 F549 A550 S577 Q578 L581 P02768 27129297 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG 5id7 B 2.26 BS03 6A4 B 3 K199 S202 F211 W214 R218 L219 L238 H242 V344 E450 S454 L457 R484 R485 K197 S200 F209 W212 R216 L217 L236 H240 V342 E448 S452 L455 R482 R483 P02768 27129297 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG 5id9 A 2.48 BS01 6A4 A 1 F205 R208 A209 A212 T235 A349 K350 S479 L480 A481 F202 R205 A206 A209 T232 A346 K347 S476 L477 A478 F7BAY6 27129297 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKAGCLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYATVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA 5ii0 A 2.10 BS01 III D 1 L40 D77 W79 F99 P100 D101 F102 H121 E123 N124 W128 S129 Y131 T132 N135 L1 D38 W40 F60 P61 D62 F63 H82 E84 N85 W89 S90 Y92 T93 N96 P30988 LYVVGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFT 5ii0 B 2.10 BS01 III E 1 D77 W79 F99 D101 F102 H121 W128 S129 Y131 T132 N135 D44 W46 F66 D68 F69 H88 W95 S96 Y98 T99 N102 P30988 IEPKPFLYVVGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNA 5ii0 C 2.10 BS01 III F 1 F39 L40 Y41 D77 W79 F99 P100 D101 H121 E123 W128 S129 Y131 T132 N135 F1 L2 Y3 D39 W41 F61 P62 D63 H83 E85 W90 S91 Y93 T94 N97 P30988 FLYVVGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFT 5inj A 1.40 BS01 TRP A 1 F85 L86 E94 W165 F220 L293 H312 R316 Y364 Y380 F53 L54 E62 W133 F188 L252 H271 R275 Y323 Y339 ALLGDLATGQLTRLCEVAGLTEADTAAYTGVLIESLGTSAGRPLSLPPPSRTFLSDDHTPVEFSLAFLPGRAPHLRVLVEPGCSSGDDLAENGRAGLRAVHTMADRWGFSTEQLDRLEDLFFPSSPEGPLALWCALELRSGGVPGVKVYLNPAANGADRAAETVREALARLGHLQAFDALPRADGFPFLALDLGDWDAPRVKIYLKHLGMSAADAGSLPRMSPAPSREQLEEFFRTAGDLPATGRLAGRPALTCHSFTETATGRPSGYTLHVPVRDYVRHDGEARDRAVAVLREHDMDSAALDRALAAVSPRPLSDGVGLIAYLALVHQRGRPTRVTVYVSSEAYEVRPPRETVP 5inj A 1.40 BS02 6C7 A 1 R108 L110 W165 K179 Y181 F220 R232 K234 Y236 H312 R376 Y380 R76 L78 W133 K147 Y149 F188 R200 K202 Y204 H271 R335 Y339 ALLGDLATGQLTRLCEVAGLTEADTAAYTGVLIESLGTSAGRPLSLPPPSRTFLSDDHTPVEFSLAFLPGRAPHLRVLVEPGCSSGDDLAENGRAGLRAVHTMADRWGFSTEQLDRLEDLFFPSSPEGPLALWCALELRSGGVPGVKVYLNPAANGADRAAETVREALARLGHLQAFDALPRADGFPFLALDLGDWDAPRVKIYLKHLGMSAADAGSLPRMSPAPSREQLEEFFRTAGDLPATGRLAGRPALTCHSFTETATGRPSGYTLHVPVRDYVRHDGEARDRAVAVLREHDMDSAALDRALAAVSPRPLSDGVGLIAYLALVHQRGRPTRVTVYVSSEAYEVRPPRETVP 5ip7 A 3.52 BS01 ZN A 1 C107 C110 C148 C167 C105 C108 C146 C165 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFSKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ip7 A 3.52 BS02 ZN A 2 C67 C70 C77 H80 C65 C68 C75 H78 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFSKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ip7 A 3.52 BS03 MG A 1 D481 D483 D485 D471 D473 D475 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFSKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ip7 B 3.52 BS01 III Q 1 N1040 E1041 I1050 L1058 N934 E935 I944 L952 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVELAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEADVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5ip7 B 3.52 BS02 ZN B 1 C1163 C1166 C1182 C1185 C1057 C1060 C1076 C1079 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVELAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEADVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5ip7 C 3.52 BS01 ZN C 1 C86 C88 C92 C95 C84 C86 C90 C93 P16370 EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQD 5ip7 I 3.52 BS01 ZN I 1 C7 C10 C29 C32 C6 C9 C28 C31 P27999 TTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQ 5ip7 I 3.52 BS02 ZN I 2 C75 C78 C103 C106 C74 C77 C102 C105 P27999 TTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQ 5ip7 J 3.52 BS01 ZN J 1 C7 C10 C45 C46 C7 C10 C45 C46 P22139 MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKFLRYNP 5ip7 L 3.52 BS01 ZN L 1 C31 C34 C48 C51 C7 C10 C24 C27 P40422 ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR 5ip9 A 3.90 BS01 ZN A 1 C107 C110 C148 C167 C105 C108 C146 C165 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFSKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ip9 A 3.90 BS02 ZN A 2 C67 C70 C77 H80 C65 C68 C75 H78 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFSKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ip9 A 3.90 BS03 MG A 1 D481 D483 D485 D471 D473 D475 2.7.7.6 P04050 GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFSKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ip9 B 3.90 BS01 III Q 1 N1040 E1041 D1043 L1058 N934 E935 D937 L952 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVELAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEADVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5ip9 B 3.90 BS02 ZN B 1 C1163 C1166 C1182 C1185 C1057 C1060 C1076 C1079 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVELAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEADVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5ip9 C 3.90 BS01 ZN C 1 C86 C88 C92 C95 C84 C86 C90 C93 P16370 EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQD 5ip9 I 3.90 BS01 ZN I 1 C7 C10 C29 C32 C6 C9 C28 C31 P27999 TTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQ 5ip9 I 3.90 BS02 ZN I 2 C75 C78 C103 C106 C74 C77 C102 C105 P27999 TTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQ 5ip9 J 3.90 BS01 ZN J 1 C7 C10 C45 C46 C7 C10 C45 C46 P22139 MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKFLRYNP 5ip9 L 3.90 BS01 ZN L 1 C31 C34 C48 C51 C7 C10 C24 C27 P40422 ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR 5ism A 2.00 BS01 6DG A 1 R125 E205 E206 F357 Y547 S630 Y631 Y662 Y666 N710 V711 H740 R87 E167 E168 F319 Y509 S592 Y593 Y624 Y628 N672 V673 H702 3.4.14.5 P27487 27106708 TRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 5ism B 2.00 BS01 6DG B 1 R125 E205 E206 F357 R358 Y547 S630 Y631 W659 Y662 Y666 N710 V711 H740 R87 E167 E168 F319 R320 Y509 S592 Y593 W621 Y624 Y628 N672 V673 H702 3.4.14.5 P27487 27106708 TRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 5j32 A 1.93 BS01 MG A 1 D288 D292 D258 D262 1.1.1.85 P93832 QMGRGSEFGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDS 5j32 A 1.93 BS02 IPM A 1 R136 R174 Y181 D288 R106 R144 Y151 D258 1.1.1.85 P93832 QMGRGSEFGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDS 5j32 A 1.93 BS03 IPM A 2 K232 N234 V235 D264 K202 N204 V205 D234 1.1.1.85 P93832 QMGRGSEFGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDS 5j32 B 1.93 BS01 IPM A 1 K232 N234 V235 D264 K197 N199 V200 D229 1.1.1.85 P93832 SEFGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDSQ 5j32 B 1.93 BS02 MG A 2 D288 D292 D253 D257 1.1.1.85 P93832 SEFGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDSQ 5j32 B 1.93 BS03 IPM A 3 R136 R146 R174 Y181 D288 R101 R111 R139 Y146 D253 1.1.1.85 P93832 SEFGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDSQ 5j32 C 1.93 BS01 MG C 1 D288 D292 D248 D252 1.1.1.85 P93832 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKS 5j32 C 1.93 BS02 IPM C 1 R136 R174 Y181 D288 R96 R134 Y141 D248 1.1.1.85 P93832 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKS 5j32 C 1.93 BS03 IPM C 2 K232 N234 V235 D264 K192 N194 V195 D224 1.1.1.85 P93832 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKS 5j32 D 1.93 BS01 IPM C 1 K232 V235 D264 K195 V198 D227 1.1.1.85 P93832 FGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 5j32 D 1.93 BS02 MG C 2 D288 D292 D251 D255 1.1.1.85 P93832 FGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 5j32 D 1.93 BS03 IPM C 3 E129 R136 R146 R174 Y181 D288 E92 R99 R109 R137 Y144 D251 1.1.1.85 P93832 FGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSV 5j34 A 1.83 BS01 MG A 1 D288 D292 D248 D252 1.1.1.85 P93832 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDMANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDS 5j34 B 1.83 BS01 MG B 1 D288 D292 D248 D252 1.1.1.85 P93832 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDMANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDS 5j34 C 1.83 BS01 MG C 1 D288 D292 D248 D252 1.1.1.85 P93832 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDMANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDS 5j34 D 1.83 BS01 MG D 1 D288 D292 D248 D252 1.1.1.85 P93832 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDMANVLEASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMGEEVLKSVDS 5j92 A 1.95 BS01 FE2 A 1 H114 D116 H263 H81 D83 H230 1.14.11.- Q13Q05 MSLNVEAAHPFIAARIHGLDLSKPLSDERIVEIEQASGQYPVLIFPRQYIDDDQLLAFAAGFGPLQVDRRRMNNLTSRRWHSDASYLPLPARYSFLLSYIVPAVGGQTQFADMRAAYDKLPDHLRKVVEGLSCHYDIMASRAAAGFYDASDEERKALAPCIHELVRTHPISGRKSLYLSSHATHVVGWPEPEGRDLLRELTEFATQPQFVYSHEWSVRDLVMWDNRALMHRGRPHIPETDVREMHRATTLDDRTWTRG 5j92 B 1.95 BS01 FE2 B 1 H114 D116 H263 R279 H82 D84 H231 R247 1.14.11.- Q13Q05 SLNVEAAHPFIAARIHGLDLSKPLSDERIVEIEQASGQYPVLIFPRQYIDDDQLLAFAAGFGPLQVAVDRRRMNNLTSRRWHSDASYLPLPARYSFLLSYIVPAVGGQTQFADMRAAYDKLPDHLRKVVEGLSCHYDIMASRAAAGFYDASDEERKALAPCIHELVRTHPISGRKSLYLSSHATHVVGWPEPEGRDLLRELTEFATQPQFVYSHEWSVRDLVMWDNRALMHRGRPHIPETDVREMHRATTLDDRTWTRG 5j92 C 1.95 BS01 FE2 C 1 H114 D116 H263 R279 H82 D84 H231 R247 1.14.11.- Q13Q05 SLNVEAAHPFIAARIHGLDLSKPLSDERIVEIEQASGQYPVLIFPRQYIDDDQLLAFAAGFGPLQVAVDRRRMNNLTSRRWHSDASYLPLPARYSFLLSYIVPAVGGQTQFADMRAAYDKLPDHLRKVVEGLSCHYDIMASRAAAGFYDASDEERKALAPCIHELVRTHPISGRKSLYLSSHATHVVGWPEPEGRDLLRELTEFATQPQFVYSHEWSVRDLVMWDNRALMHRGRPHIPETDVREMHRATTLDDRTWTR 5j92 D 1.95 BS01 FE2 D 1 H114 D116 H263 R279 H81 D83 H230 R246 1.14.11.- Q13Q05 SLNVEAAHPFIAARIHGLDLSKPLSDERIVEIEQASGQYPVLIFPRQYIDDDQLLAFAAGFGPLQVAVRRRMNNLTSRRWHSDASYLPLPARYSFLLSYIVPAVGGQTQFADMRAAYDKLPDHLRKVVEGLSCHYDIMASRAAAGFYDASDEERKALAPCIHELVRTHPISGRKSLYLSSHATHVVGWPEPEGRDLLRELTEFATQPQFVYSHEWSVRDLVMWDNRALMHRGRPHIPETDVREMHRATTLDDRTWTR 5jc8 A 1.45 BS01 MG A 1 C19 G25 P200 M201 C16 G22 P197 M198 Q13GE3 AGRLQGKVALVTGAGCIGPGWGNGRAIAVRFAEEGAHVIAVDRDLASMDATLELVRAAGGSVTPCLCDVTDSASVERLVADSVARCGRVDILVNNVGAPSPGGPVALDEAQWAMQLELNLTTAFLMCKYVLPVMEQQGGGAIVNIASTSGIRWTGAAQVGYAAAKAGMIQMGRVVAVEYAAKNVRVNSVVPGLLHTPMVDTKIAHNGGDVELLLRKRQARIPMPFMGDGRDTANAALFLASDEARFVTGTEIVVDGGMSARCD 5jc8 D 1.45 BS01 MG D 1 C19 G25 P200 M201 C16 G22 P197 M198 Q13GE3 AGRLQGKVALVTGAGCIGPGWGNGRAIAVRFAEEGAHVIAVDRDLASMDATLELVRAAGGSVTPCLCDVTDSASVERLVADSVARCGRVDILVNNVGAPSPGGPVALDEAQWAMQLELNLTTAFLMCKYVLPVMEQQGGGAIVNIASTSGIRWTGAAQVGYAAAKAGMIQMGRVVAVEYAAKNVRVNSVVPGLLHTPMVDTKIAHNGDVELLLRKRQARIPMPFMGDGRDTANAALFLASDEARFVTGTEIVVDGGMSARCD 5jdf A 2.65 BS01 CA A 1 I118 D121 G122 D127 I118 D121 G122 D127 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdf A 2.65 BS02 CA A 2 T50 S51 E54 T209 E213 T50 S51 E54 T202 E206 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdg A 2.41 BS01 NA A 1 A47 T50 S51 E213 S236 A47 T50 S51 E206 S229 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdg A 2.41 BS02 NA A 2 T50 S51 E54 T209 S210 E213 T50 S51 E54 T202 S203 E206 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdg A 2.41 BS03 CA A 1 I118 D121 G122 D127 I118 D121 G122 D127 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdh A 2.20 BS01 NA A 1 A47 T50 S51 E213 S236 A47 T50 S51 E209 S232 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdh A 2.20 BS02 CA A 1 I118 D121 G122 D127 I118 D121 G122 D127 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdh A 2.20 BS03 CA A 2 T50 S51 E54 T209 S210 E213 T50 S51 E54 T205 S206 E209 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdm A 2.56 BS01 NA A 1 A47 T50 S51 E213 S236 A47 T50 S51 E207 S230 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIENPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLR 5jdm A 2.56 BS02 NA A 2 T50 S51 P53 E54 T209 S210 E213 T50 S51 P53 E54 T203 S204 E207 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIENPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLR 5jdn A 2.30 BS01 NA A 1 A47 T50 S51 E213 N232 S236 A47 T50 S51 E209 N228 S232 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdq A 2.50 BS01 NA A 1 A47 T50 S51 E213 S236 A47 T50 S51 E208 S231 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIENNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdq A 2.50 BS02 NA A 2 T50 S51 P53 E54 T209 S210 P212 E213 T50 S51 P53 E54 T204 S205 P207 E208 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIENNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5jdq A 2.50 BS03 NA A 3 E54 S77 A206 T209 S210 E54 S77 A201 T204 S205 Q57556 MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIENNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM 5je2 A 1.52 BS01 SAH A 1 F7 F14 R24 A47 C48 G49 F53 D69 I70 S71 M74 R94 D95 V96 A111 W112 Y116 M126 F3 F10 R20 A43 C44 G45 F49 D65 I66 S67 M70 R90 D91 V92 A107 W108 Y112 M122 Q9LBJ0 27070241 ARFDSIGGLFEDFTQSAAQRAIEVRTIFHMIGDVSGKSVLDLACGFGFFGREIYRRGAAKVVGVDISEKMIELAREESRKYGDPLEFHVRDVANMEPLGQFDLVNAAWLFNYADSVENLRKMFKVVRASLKPDGKLVAYTVDPDFSLAKGNFAKYGVNVLNERAWGPGYRHDAEFVTDPPSQFSFYRWSRADYESAIADAGFSHFEWQKPLLEADDIATHPPGFWDVFQNNCLQTGLVCKP 5je2 B 1.52 BS01 SAH B 1 F7 F14 R24 A47 C48 G49 F53 D69 I70 S71 M74 R94 D95 V96 A111 W112 Y116 M126 F3 F10 R20 A43 C44 G45 F49 D65 I66 S67 M70 R90 D91 V92 A107 W108 Y112 M122 Q9LBJ0 27070241 ARFDSIGGLFEDFTQSAAQRAIEVRTIFHMIGDVSGKSVLDLACGFGFFGREIYRRGAAKVVGVDISEKMIELAREESRKYGDPLEFHVRDVANMEPLGQFDLVNAAWLFNYADSVENLRKMFKVVRASLKPDGKLVAYTVDPDFSLAKGNFAKYGVNVLNERAWGPGYRHDAEFVTDPPSQFSFYRWSRADYESAIADAGFSHFEWQKPLLEADDIATHPPGFWDVFQNNCLQTGLVCKP 5je8 A 2.10 BS01 NAD A 1 I7 G10 N11 M12 D31 L32 S64 L65 P66 A70 V74 S95 T96 V121 G124 K172 F234 L238 I7 G10 N11 M12 D31 L32 S64 L65 P66 A70 V74 S95 T96 V121 G124 K172 F234 L238 1.1.1.31 Q81DR6 27120461 MKKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDVVFTSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVSGGVIGAENRTLTFMVGGSKDVYEKTESIMGVLGANIFHVSEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKNNMDLDKMFDILNVSYGQSRIYERNYKSFIAPENYEPGFTVNLLKKDLGFAVDLAKESELHLPVSEMLLNVYDEASQAGYGENDMAALYKKVSEQL 5je8 B 2.10 BS01 NAD B 1 G8 G10 N11 M12 D31 L32 S64 L65 P66 V74 S95 T96 V121 G124 L238 G10 G12 N13 M14 D33 L34 S66 L67 P68 V76 S97 T98 V123 G126 L240 1.1.1.31 Q81DR6 27120461 DPMKKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDVVFTSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVSGGVIGAENRTLTFMVGGSKDVYEKTESIMGVLGANIFHVSEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKNNMDLDKMFDILNVSYGQSRIYERNYKSFIAPENYEPGFTVNLLKKDLGFAVDLAKESELHLPVSEMLLNVYDEASQAGYGENDMAALYKKVSEQLI 5je8 C 2.10 BS01 NAD C 1 G8 G10 N11 M12 D31 L32 L65 P66 V74 T96 V121 G124 L238 G7 G9 N10 M11 D30 L31 L64 P65 V73 T95 V120 G123 L237 1.1.1.31 Q81DR6 27120461 KKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDVVFTSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVSGGVIGAENRTLTFMVGGSKDVYEKTESIMGVLGANIFHVSEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKNNMDLDKMFDILNVSYGQSRIYERNYKSFIAPENYEPGFTVNLLKKDLGFAVDLAKESELHLPVSEMLLNVYDEASQAGYGENDMAALYKKVSEQ 5je8 D 2.10 BS01 NAD D 1 G10 N11 M12 D31 L32 S64 L65 P66 S95 T96 V121 L238 G10 N11 M12 D31 L32 S64 L65 P66 S95 T96 V121 L238 1.1.1.31 Q81DR6 27120461 MKKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDVVFTSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVSGGVIGAENRTLTFMVGGSKDVYEKTESIMGVLGANIFHVSEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKNNMDLDKMFDILNVSYGQSRIYERNYKSFIAPENYEPGFTVNLLKKDLGFAVDLAKESELHLPVSEMLLNVYDEASQAGYGENDMAALYKKVSEQLI 5jht A 1.75 BS01 MN A 1 H41 D108 E119 I120 H46 D93 E104 I105 P03433 GPLGSMEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDASKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSER 5jht A 1.75 BS02 MN A 2 H41 E80 D108 H46 E65 D93 P03433 GPLGSMEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDASKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSER 5jhv A 2.75 BS01 MN A 1 H41 D108 E119 I120 H46 D93 E104 I105 P03433 GPLGSMEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDASKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSER 5jhv A 2.75 BS02 MN A 2 H41 E80 D108 H46 E65 D93 P03433 GPLGSMEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDASKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSER 5jhv B 2.75 BS01 MN B 1 H41 D108 E119 I120 H46 D93 E104 I105 P03433 GPLGSMEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDASKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSER 5jhv B 2.75 BS02 MN B 2 E80 L106 P107 D108 E119 E65 L91 P92 D93 E104 P03433 GPLGSMEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDASKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSER 5jil A 1.85 BS01 NAG A 1 N241 L274 E275 N222 L255 E256 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5jil A 1.85 BS02 NAG A 2 N304 S305 D330 Y331 S332 G333 V338 N285 S286 D311 Y312 S313 G314 V319 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5jil A 1.85 BS03 NAG A 3 D300 R302 N311 A314 F324 N326 T327 A329 D281 R283 N292 A295 F305 N307 T308 A310 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5jil A 1.85 BS04 NAG A 4 N31 D32 L353 N355 N12 D13 L334 N336 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5jil A 1.85 BS05 NAG A 5 Y367 N369 V370 Y348 N350 V351 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5jil A 1.85 BS06 NAG A 6 F87 N89 I145 T147 F68 N70 I126 T128 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5jil A 1.85 BS07 ZN A 1 E48 H52 D56 H336 E29 H33 D37 H317 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5jil A 1.85 BS08 6KL A 1 D39 A40 Y46 W57 S74 G75 N104 H336 H340 D20 A21 Y27 W38 S55 G56 N85 H317 H321 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5jil A 1.85 BS09 6KL A 2 L114 Y184 F207 S211 R212 G213 S214 S215 T248 F276 L95 Y165 F188 S192 R193 G194 S195 S196 T229 F257 3.1.1.53 Q3HS77 FNEPLNIVSHLNDDWFLFGDARSDCTYVENNGHPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFTDFYNYSGEGDQVIFYEGVNFSPSHGFKCLANGDNKIWMGNKARFYARLYEKMAQYRSLSIVTVSYAYGGNAKPTSICKDNKLTLNNPTFISKESNYADYYYVSEANFTLQGCDEFIVPLCVFNGHSRGSSSDPANTYYMDSQMYYNTVTGVFYGFNSTLDVGTTVQNPGLDLTCSYLALSPGNYKAVSLEFLLSLPSKAICLLKPKRFMPVQVVDSRWNSTRQSDNMTAVACQLPYCFFRNTSADYSGDTHDVHHGDLYFRQLLSGLLYNVSCIAQQGAFLYNNVSSIWPVYGYGHCPTAANI 5jla A 1.45 BS01 NAD A 1 G16 S19 G20 I21 D40 R41 L60 D61 V62 C88 A89 G90 I112 I139 A140 S141 Y153 K157 P183 G184 F185 T186 T188 P189 A190 G14 S17 G18 I19 D38 R39 L58 D59 V60 C86 A87 G88 I110 I137 A138 S139 Y151 K155 P181 G182 F183 T184 T186 P187 A188 Q13GR0 ASAEFNGAIAVVTGAGSGIGRACAELLSRSGANVIVADRDIEAATRVARATGGKTLVLDVGEDASVTAAANEVRARYGVADVLVNCAGVLQRTLPPGELAQREWDVVSRIDLRGTYLCCAAFGAPMADRRRGSIVNIASVAGMRSGPLHAYGPAKAGVISLTETLAGEWGPKGVRVNCVSPGFTQTPALERGFTTLKADVLRDAAALGHIVSANEIAEAVVFLASERASAITGVNLPVDAGYLIAGSWAAYGGLRRE 5jla B 1.45 BS01 NAD B 1 G16 S19 G20 I21 D40 R41 L60 D61 V62 G63 C88 A89 G90 I112 I139 A140 S141 Y153 K157 P183 G184 F185 T186 T188 P189 A190 R193 G14 S17 G18 I19 D38 R39 L58 D59 V60 G61 C86 A87 G88 I110 I137 A138 S139 Y151 K155 P181 G182 F183 T184 T186 P187 A188 R191 Q13GR0 ASAEFNGAIAVVTGAGSGIGRACAELLSRSGANVIVADRDIEAATRVARATGGKTLVLDVGEDASVTAAANEVRARYGVADVLVNCAGVLQRTLPPGELAQREWDVVSRIDLRGTYLCCAAFGAPMADRRRGSIVNIASVAGMRSGPLHAYGPAKAGVISLTETLAGEWGPKGVRVNCVSPGFTQTPALERGFTTHTLKADVLRDAAALGHIVSANEIAEAVVFLASERASAITGVNLPVDAGYLIAGSWAAYGGLRR 5jla C 1.45 BS01 NAD C 1 G16 S19 G20 I21 D40 R41 L60 D61 V62 C88 A89 G90 I112 I139 A140 S141 Y153 K157 P183 G184 F185 T186 T188 P189 A190 G14 S17 G18 I19 D38 R39 L58 D59 V60 C86 A87 G88 I110 I137 A138 S139 Y151 K155 P181 G182 F183 T184 T186 P187 A188 Q13GR0 ASAEFNGAIAVVTGAGSGIGRACAELLSRSGANVIVADRDIEAATRVARATGGKTLVLDVGEDASVTAAANEVRARYGVADVLVNCAGVLQRTLPPGELAQREWDVVSRIDLRGTYLCCAAFGAPMADRRRGSIVNIASVAGMRSGPLHAYGPAKAGVISLTETLAGEWGPKGVRVNCVSPGFTQTPALERGFTTHTLKADVLRDAAALGHIVSANEIAEAVVFLASERASAITGVNLPVDAGYLIAGSWAAYGGLRR 5jla D 1.45 BS01 NAD D 1 G16 S19 G20 I21 D40 R41 L60 D61 V62 C88 A89 G90 I112 I139 A140 S141 Y153 K157 P183 G184 F185 T186 T188 P189 A190 G14 S17 G18 I19 D38 R39 L58 D59 V60 C86 A87 G88 I110 I137 A138 S139 Y151 K155 P181 G182 F183 T184 T186 P187 A188 Q13GR0 ASAEFNGAIAVVTGAGSGIGRACAELLSRSGANVIVADRDIEAATRVARATGGKTLVLDVGEDASVTAAANEVRARYGVADVLVNCAGVLQRTLPPGELAQREWDVVSRIDLRGTYLCCAAFGAPMADRRRGSIVNIASVAGMRSGPLHAYGPAKAGVISLTETLAGEWGPKGVRVNCVSPGFTQTPALERGFTTHTLKADVLRDAAALGHIVSANEIAEAVVFLASERASAITGVNLPVDAGYLIAGSWAAYGGLRRE 5jme A 2.34 BS01 III F 1 Y55 R59 R79 V108 M116 I118 D164 S166 S167 Y54 R58 R78 V107 M115 I117 D163 S165 S166 Q8WSF8 DKLHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRE 5jme A 2.34 BS02 III G 1 W147 Y188 C190 C191 E193 Y195 W146 Y187 C189 C190 E192 Y194 Q8WSF8 DKLHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRE 5jme B 2.34 BS01 III F 1 W147 Y188 C190 C191 E193 Y195 W149 Y190 C192 C193 E195 Y197 Q8WSF8 KLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 5jme B 2.34 BS02 III I 1 T36 Y55 Q57 R59 R79 V108 M116 I118 D159 D164 S166 S167 T38 Y57 Q59 R61 R81 V110 M118 I120 D161 D166 S168 S169 Q8WSF8 KLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 5jme C 2.34 BS01 III H 1 Y55 Q57 R79 V108 M116 I118 D164 S166 S167 Y53 Q55 R77 V106 M114 I116 D162 S164 S165 Q8WSF8 KLHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 5jme C 2.34 BS02 III I 1 W147 Y188 C190 C191 E193 Y195 W145 Y186 C188 C189 E191 Y193 Q8WSF8 KLHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 5jme D 2.34 BS01 III H 1 W147 Y188 C190 C191 E193 Y195 W145 Y186 C188 C189 E191 Y193 Q8WSF8 KLHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 5jme E 2.34 BS01 III G 1 T36 Y55 Q57 R79 V108 M116 I118 D164 S166 S167 T37 Y56 Q58 R80 V109 M117 I119 D165 S167 S168 Q8WSF8 DDDKLHSQANLMRLKSDLFNYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 5job A 1.45 BS01 THP A 1 R35 D40 K84 Y85 R87 L89 Y113 Y115 R29 D34 K72 Y73 R75 L77 Y101 Y103 3.1.31.1 P00644 LHKEPATLIKAIDGDTVKKMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYAYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLRKAEAQAKKEKLNIWS 5job A 1.45 BS02 CA A 1 D21 D40 T41 E43 D15 D34 T35 E37 3.1.31.1 P00644 LHKEPATLIKAIDGDTVKKMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYAYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLRKAEAQAKKEKLNIWS 5jpd A 1.72 BS01 CD A 1 H67 H140 E206 D281 H37 H110 E176 D251 Q8Y653 GKLNVVATYSILADIVKNVGGNKIELHSIVPVGVDPHEYDPLPANIQSAADADLIFYNGLNLETGNGWFDRMLETADKSREDKNQVVELSKGVKPKYLTEKGKTSETDPHAWLDLHNGIIYTENVRDALVKADPDNADFYKENAKKYIDKLATLDKEAKQKFADLPENQKTLVTSEGAFKYFAARYGLKAAYIWEINTESQGTPDQMKQIVGIVEKEKVPNLFVETSVDPRSMESVSKETGVPIFAKIFTDSTAKKGEVGDTYLEMMRYNLDKIHDGLAK