2mt9 A BS01 FMN A 1 S9 S10 T11 Y13 T14 P54 T55 W56 D57 F58 G59 Q62 L87 G88 D89 Y93 W96 F97 S9 S10 T11 Y13 T14 P54 T55 W56 D57 F58 G59 Q62 L87 G88 D89 Y93 W96 F97 P0ABY4 25380767 MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLMEQYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALGMLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSWCEQILNEMAEHYA 2naa A BS01 ZN A 1 C9 C12 H31 C34 C9 C12 H31 C34 2.1.1.43 O88491 26896805 GAMEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHD 2naa A BS02 ZN A 2 C21 C26 C47 H50 C21 C26 C47 H50 2.1.1.43 O88491 26896805 GAMEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHD 2nab A BS01 ZN A 1 C14 C17 H30 C14 C17 H30 Q5SXI5 26896805 GAMEVQTSQKSYVCPNCGKIFRWRVNFIRHLRSRREQKPHK 3jcr A 7.00 BS01 NUC H 1 T224 N457 A458 T192 N425 A426 Q6P2Q9 26912367 SEEKLQEKARKWQQLQAKRYAEKRKFGFMPPEHVRKIIRDHGDMTNRKFRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVPVLYHITGAISFVNEIPWVIEPVYISQWGSMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNILDVEPLEAIQLELDPEEDAPVLDWFYDHQPLRDSRKYVNGSTYQRWQFTLPMMSTLYRLANQLLTDLVDDNYFYLFDLKAFFTSKALNMAIPGGPKFEPLVRDINLQDEDWNEFNDINKIIIRQPIRTEYKIAFPYLYNNLPHHVHLTWYHTPNVVFIKTEDPDLPAFYFDPLINPISHRHSVKSQEPLPDDDEEFELPEFVEPFLKDTPLYTDNTANGIALLWAPRPFNLRSGRTRRALDIPLVKNWYREHCPAGQPVKVRVSYQKLLKYYVLNALKHRPPKAQKKRYLFRSFKATKFFQSTKLDWVEVGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREVLRLTKLVVDSHVQYRLGNVDAFQLADGLQYIFAHVGQLTGMYRYKYKLMRQIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAAGWRVWLFFMRGITPLLERWLGNLLARQFEGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPEGIKQNKARTILQHLSEAWRCWKANIPWKVPGLPTPIENMILRYVKAKADWWTNTAHYNRERIRRGATVDKTVCKKNLGRLTRLYLKAEQERQHNYLKDGPYITAEEAVAVYTTTVHWLESRRFSPIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPADTEPPPLLVYKWCQGINNLQDVWETSEGECNVMLESRFEKMYEKIDLTLLNRLLRLIVDHNIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQYYGLVMDLLVLGLHRASEMAGPPQMPNDFLSFQDIATEAAHPIRLFCRYIDRIHIFFRFTADEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSVTTVQWENSFVSVYSKDNPNLLFNMCGFECRILPKCRTSYEEFTHKDGVWNLQNEVTKERTAQCFLRVDDESMQRFHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPGQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIIITCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNPKGYLPSHYERVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEFYHEVHRPSHF 4wth A 2.25 BS01 ZN A 1 Y17 H39 Y17 H39 P54252 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAASEELRKRREAYFEKQQQKQQQQQQQQQQGDLSG 4wth A 2.25 BS02 MAL A 1 N12 D14 K15 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 N12 D14 K15 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 P54252 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAASEELRKRREAYFEKQQQKQQQQQQQQQQGDLSG 4wy9 A 1.40 BS01 ACT A 1 L238 H251 L261 Y287 A289 S290 L197 H210 L220 Y246 A248 S249 Q0P8B2 26923153 NITKNTEDILASITKEYATQTQGIFGEMIALNKSISGTLTEMFRSTSKEDLDIDNITNIITNTFDNSAYSNFTYLYLIDPPEYFKEESKFFNTQSGKFVMLYADEEGIKAIQASDEIANLQVVQDILKKAKYGENKVYIGRPIKMNLEGQDFDAVNVAIPIFDRKNQVVGVIGMTLDFSDIATYLLDPKGQKYDGELRVLLNSDGFMAIHPNKNLVLKNLKDINPNKGAQETYKAISEGKNGVFNYIASDGDDSYAAINSFKVQDSSWAVLVTAPKYSVFKPLKK 4x5w A 1.34 BS01 III C 1 Q9 F24 I31 F32 R50 A52 S53 F54 G58 N62 V65 D66 A68 N69 I72 M73 Q10 F25 I32 F33 R51 A53 S54 F55 G59 N63 V66 D67 A69 N70 I73 M74 P01903 MIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEF 4x5w B 1.34 BS01 III C 1 W9 F13 D57 Y60 W61 L67 R71 T77 Y78 H81 N82 V85 G86 W8 F12 D56 Y59 W60 L66 R70 T76 Y77 H80 N81 V84 G85 P04229 DTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVYPSLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSK 4x89 A 2.62 BS01 2CV A 1 M189 P193 N194 W196 I200 M59 P63 N64 W66 I70 A0L5S6 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDAM 4x89 B 2.62 BS02 2CV B 1 M189 N194 W196 M59 N64 W66 A0L5S6 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4x89 C 2.62 BS02 AG C 1 P187 N190 V191 P58 N61 V62 A0L5S6 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4x89 D 2.62 BS01 2CV C 1 F142 S165 F13 S36 A0L5S6 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4x89 D 2.62 BS02 2CV D 1 M189 W196 M60 W67 A0L5S6 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4x8a B 3.02 BS01 2CV A 1 S165 K166 F172 S36 K37 F43 A0L5S6 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDAMAI 4xcq A 2.39 BS01 GDP A 1 G11 Q12 G13 N16 T95 A97 G98 G99 T100 G101 V126 E132 N164 E170 I173 N174 G12 Q13 G14 N17 T96 A98 G99 G100 T101 G102 V127 E133 N165 E171 I174 N175 Q331T7 HMKNKIVFAPIGQGGGNIVDTLLGICGDYNALFINTSKKDLDSLKHAKHTYHIPYAEGCGKERKKAVGYAQTYYKQIIAQIMEKFSSCDIVIFVATMAGGTGSGITPPILGLAKQMYPNKHFGFVGVLPKATEDIDEHMNAIACWNDIMRSTNEGKDISIYLLDNNKREKESDINKEFATLFNDFMNMSEGVVDEDEISKLLTMKKSNVILEFDDKEDIQVALAKSLKESIFAEYTTNTCEFMGISTTRVVDVEAIKSIVGYPRRTFKGYNSKKNIVVATGIEPQKTTVQMMNEIIEDKMKQR 4xe5 A 3.90 BS02 MG A 2 G277 K724 D745 G251 K698 D719 3.6.3.9 Q08DA1 ERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQDNLPILKRAVAGDASESALLKCIEVCCGSVKEMRERYTKIVEIPFNSTNKYQLSIHKNANAGEPRHLLVMKGAPERILDRCSSILIHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDDVNFPVDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDARACVVHGSDLKDMTPEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIMAENGFLPNHLLGIRVTWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 4xe5 A 3.90 BS03 MG A 3 S780 N781 E784 D809 S754 N755 E758 D783 3.6.3.9 Q08DA1 ERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQDNLPILKRAVAGDASESALLKCIEVCCGSVKEMRERYTKIVEIPFNSTNKYQLSIHKNANAGEPRHLLVMKGAPERILDRCSSILIHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDDVNFPVDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDARACVVHGSDLKDMTPEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIMAENGFLPNHLLGIRVTWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 4xe5 A 3.90 BS04 OBN A 1 Q116 E122 P123 D126 L130 E317 G324 A328 E332 F788 T802 I805 R885 Q90 E96 P97 D100 L104 E291 G298 A302 E306 F762 T776 I779 R859 3.6.3.9 Q08DA1 ERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQDNLPILKRAVAGDASESALLKCIEVCCGSVKEMRERYTKIVEIPFNSTNKYQLSIHKNANAGEPRHLLVMKGAPERILDRCSSILIHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDDVNFPVDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDARACVVHGSDLKDMTPEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIMAENGFLPNHLLGIRVTWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 4xe5 A 3.90 BS05 CLR A 1 E873 T984 C988 P991 L994 E847 T958 C962 P965 L968 3.6.3.9 Q08DA1 ERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQDNLPILKRAVAGDASESALLKCIEVCCGSVKEMRERYTKIVEIPFNSTNKYQLSIHKNANAGEPRHLLVMKGAPERILDRCSSILIHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDDVNFPVDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDARACVVHGSDLKDMTPEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIMAENGFLPNHLLGIRVTWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 4xe5 A 3.90 BS06 CLR A 2 W929 P983 W986 F987 F990 W903 P957 W960 F961 F964 3.6.3.9 Q08DA1 ERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQDNLPILKRAVAGDASESALLKCIEVCCGSVKEMRERYTKIVEIPFNSTNKYQLSIHKNANAGEPRHLLVMKGAPERILDRCSSILIHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLLLPDEQFPEGFQFDTDDVNFPVDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDARACVVHGSDLKDMTPEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIMAENGFLPNHLLGIRVTWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 4xe5 B 3.90 BS01 CLR A 1 T53 V56 M57 T60 T35 V38 M39 T42 G3MWR4 SEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQIQKTEIAFRPNDPKSYMTYVDNIDNFLKKYRDSAQKDDMIFEDCGNVPSELKDRGELNNEQGERKVCRFKLEWLGNCSGINDETYGYKDGKPCVIIKLNRVLGFKPKPPKNESLETYPVMKYNPYVLPVQCTGKRDEDKEKVGSIEYFGLGGYPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKI 4xe5 G 3.90 BS01 CLR A 3 V14 G18 F21 V10 G14 F17 Q04645 DPFYYDYETVRNGGLIFAALAFIVGLVIILSK 4xg1 A 2.50 BS01 TME A 1 S127 I128 I174 S121 I122 I152 4.1.1.20 A1SR00 DHFNYQNRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTIAPFIELDKLLILIDLLAEKGITISHLDLGGGLGVPYDDEPPEPAEYMTAIINRMRLKLIFEPGRAIMANAGVLVTKVEFLKLNDYKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPI 4xg1 A 2.50 BS02 LLP A 1 K61 D80 S103 H200 S203 G240 E274 G276 R277 R313 Y317 Y376 M380 K55 D74 S97 H178 S181 G216 E246 G248 R249 R285 Y289 Y348 M352 4.1.1.20 A1SR00 DHFNYQNRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTIAPFIELDKLLILIDLLAEKGITISHLDLGGGLGVPYDDEPPEPAEYMTAIINRMRLKLIFEPGRAIMANAGVLVTKVEFLKLNDYKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPI 4xg1 A 2.50 BS03 LLP B 1 C348 E349 Y384 C320 E321 Y356 4.1.1.20 A1SR00 DHFNYQNRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTIAPFIELDKLLILIDLLAEKGITISHLDLGGGLGVPYDDEPPEPAEYMTAIINRMRLKLIFEPGRAIMANAGVLVTKVEFLKLNDYKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPI 4xg1 B 2.50 BS01 TME A 1 L293 K294 L292 K293 4.1.1.20 A1SR00 DHFNYQNDGRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSAAGKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNIDAGTHPYISTGLKENKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKGITISHLDLGGGLGVPYDDETPPEPAEYMTAIINRMAGRSLKLIFEPGRAIMANAGVLVTKVEFLKLNKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPI 4xg1 B 2.50 BS02 LLP A 1 C348 E349 Y384 C345 E346 Y381 4.1.1.20 A1SR00 DHFNYQNDGRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSAAGKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNIDAGTHPYISTGLKENKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKGITISHLDLGGGLGVPYDDETPPEPAEYMTAIINRMAGRSLKLIFEPGRAIMANAGVLVTKVEFLKLNKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPI 4xg1 B 2.50 BS03 TME B 1 E207 I208 A209 E206 I207 A208 4.1.1.20 A1SR00 DHFNYQNDGRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSAAGKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNIDAGTHPYISTGLKENKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKGITISHLDLGGGLGVPYDDETPPEPAEYMTAIINRMAGRSLKLIFEPGRAIMANAGVLVTKVEFLKLNKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPI 4xg1 B 2.50 BS04 TME B 2 A36 E39 R40 A35 E38 R39 4.1.1.20 A1SR00 DHFNYQNDGRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSAAGKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNIDAGTHPYISTGLKENKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKGITISHLDLGGGLGVPYDDETPPEPAEYMTAIINRMAGRSLKLIFEPGRAIMANAGVLVTKVEFLKLNKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPI 4xg1 B 2.50 BS05 LLP B 1 A59 K61 D80 S103 H200 S203 G240 E274 G276 R277 R313 Y317 Y376 M380 A58 K60 D79 S102 H199 S202 G239 E273 G275 R276 R310 Y314 Y373 M377 4.1.1.20 A1SR00 DHFNYQNDGRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSAAGKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNIDAGTHPYISTGLKENKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKGITISHLDLGGGLGVPYDDETPPEPAEYMTAIINRMAGRSLKLIFEPGRAIMANAGVLVTKVEFLKLNKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPI 4xg1 C 2.50 BS01 LLP C 1 A59 K61 D80 H200 S203 G239 G240 E274 P275 G276 R277 R313 Y317 Y376 M380 A58 K60 D79 H191 S194 G230 G231 E265 P266 G267 R268 R303 Y307 Y366 M370 4.1.1.20 A1SR00 DHFNYQNDGRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSAAGKHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPNIDAGLKENKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKGITISHLDLGGGLGVPYDDETPPEPAEYMTAIINRMAGRSLKLIFEPGRAIMANAGVLVTKVEFLKLNDKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPI 4xg1 D 2.50 BS02 TME D 1 K25 A400 K24 A380 4.1.1.20 A1SR00 DHFNYQNDGRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSAAGHPHLICYAVKANSNLAVLNLMARMGSGFDIVSVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPENKFGIEIEQALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKITISHLDLGGGLGVPYDDETPPEPAEYMTAIINRMGRSLKLIFEPGRAIMANAGVLVTKVEFLKLNDKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRSYDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILPIHH 4xhn A 2.60 BS01 MG A 1 D16 K23 D9 K16 KNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPTVDEMQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMPIGEEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEVGESYAINDLGAGTSDNAFFEDGELNKKLSTNTDLGTNKYIDEILKNIKERFMPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGPVKENVTDIVMDGMLKYAEDQKASLDKFWDKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQL 4xhn A 2.60 BS02 ANP A 1 I20 K21 K23 L237 G238 A239 G240 T241 T264 I268 E301 I304 V308 M309 V312 G372 G373 L375 F376 I13 K14 K16 L194 G195 A196 G197 T198 T221 I225 E243 I246 V250 M251 V254 G314 G315 L317 F318 KNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPTVDEMQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMPIGEEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEVGESYAINDLGAGTSDNAFFEDGELNKKLSTNTDLGTNKYIDEILKNIKERFMPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGPVKENVTDIVMDGMLKYAEDQKASLDKFWDKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQL 4xhp A 3.20 BS01 MG A 1 D16 K23 D236 D13 K20 D193 QMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMPGEEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEAEIGESYAINDLGAGTSDNAFFEDGELNKKLSTNTDLGTNKYIDEILKNIKERFMPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGDVKENVTDIVMDGMLKYAEDQKASLMKFWFKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQLNEQMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPTVQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEVEGGESYAINDLGAGTSDNAFFEDGELNLSTNTDLGTNKYIDEILKNIKERFMENEIIESPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGPVKENVTDIVMDGMLKYAEDQKASLDKFWDKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQLN 4xhp A 3.20 BS02 ADP A 1 I20 K23 L237 G238 A239 T264 I304 V308 M309 V312 G372 G373 L375 I17 K20 L194 G195 A196 T221 I246 V250 M251 V254 G314 G315 L317 QMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMPGEEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEAEIGESYAINDLGAGTSDNAFFEDGELNKKLSTNTDLGTNKYIDEILKNIKERFMPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGDVKENVTDIVMDGMLKYAEDQKASLMKFWFKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQLNEQMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPTVQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEVEGGESYAINDLGAGTSDNAFFEDGELNLSTNTDLGTNKYIDEILKNIKERFMENEIIESPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGPVKENVTDIVMDGMLKYAEDQKASLDKFWDKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQLN 4xhp A 3.20 BS03 MG A 2 K466 D679 K380 D552 QMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMPGEEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEAEIGESYAINDLGAGTSDNAFFEDGELNKKLSTNTDLGTNKYIDEILKNIKERFMPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGDVKENVTDIVMDGMLKYAEDQKASLMKFWFKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQLNEQMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPTVQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEVEGGESYAINDLGAGTSDNAFFEDGELNLSTNTDLGTNKYIDEILKNIKERFMENEIIESPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGPVKENVTDIVMDGMLKYAEDQKASLDKFWDKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQLN 4xhp A 3.20 BS04 ADP A 2 K464 K466 G681 A682 T707 I747 M752 G815 L818 K378 K380 G554 A555 T578 I610 M615 G678 L681 QMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMPGEEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEAEIGESYAINDLGAGTSDNAFFEDGELNKKLSTNTDLGTNKYIDEILKNIKERFMPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGDVKENVTDIVMDGMLKYAEDQKASLMKFWFKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQLNEQMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPTVQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEVEGGESYAINDLGAGTSDNAFFEDGELNLSTNTDLGTNKYIDEILKNIKERFMENEIIESPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGPVKENVTDIVMDGMLKYAEDQKASLDKFWDKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQLN 4y1p A 2.20 BS01 MG A 1 D225 D229 D223 D227 1.1.1.85 Q4JB37 GFVVALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSLRVIEKADMILKGPVGETAADVVVKLRLMYDLYANLRPAKSLPGLNKFGDVDILVVRENTEDLYKGLEHVISDGVTVGIKVITRAASTRIAQVALNQALRRKKKVVCVHKSNVMRITDGLFAESCRNVLKGKVEYSEMYVDAAAANLVRNPQAFDVIVTENTYGDILSDEAGQIAGSLGISPSANIGDRKSLFEPVHGAAFDIAGKNIANPTAFLLSVGMMLDRMQELSGDIRYNNAAKSLRDAIYSVYSEGKYLTPDVGGSSTTDEMISAIRSKIG 4y1p A 2.20 BS02 IPM A 1 A78 R86 R96 R117 Y124 D225 A77 R85 R95 R115 Y122 D223 1.1.1.85 Q4JB37 GFVVALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSLRVIEKADMILKGPVGETAADVVVKLRLMYDLYANLRPAKSLPGLNKFGDVDILVVRENTEDLYKGLEHVISDGVTVGIKVITRAASTRIAQVALNQALRRKKKVVCVHKSNVMRITDGLFAESCRNVLKGKVEYSEMYVDAAAANLVRNPQAFDVIVTENTYGDILSDEAGQIAGSLGISPSANIGDRKSLFEPVHGAAFDIAGKNIANPTAFLLSVGMMLDRMQELSGDIRYNNAAKSLRDAIYSVYSEGKYLTPDVGGSSTTDEMISAIRSKIG 4y1p B 2.20 BS01 IPM B 1 A79 V83 R86 R96 R117 Y124 D225 A78 V82 R85 R95 R116 Y123 D224 1.1.1.85 Q4JB37 GFVVALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSLRVIEKADMILKGPVGETAADVVVKLRLMYDLYANLRPAKSLPGLENKFGDVDILVVRENTEDLYKGLEHVISDGVTVGIKVITRAASTRIAQVALNQALRRKKKVVCVHKSNVMRITDGLFAESCRNVLKGKVEYSEMYVDAAAANLVRNPQAFDVIVTENTYGDILSDEAGQIAGSLGISPSANIGDRKSLFEPVHGAAFDIAGKNIANPTAFLLSVGMMLDRMQELSGDIRYNNAAKSLRDAIYSVYSEGKYLTPDVGGSSTTDEMISAIRSKIG 4y4l A 2.00 BS01 48N A 1 G72 G74 S75 S76 I96 E97 S98 S99 G104 G105 C169 V170 T234 T235 G236 H237 F241 F244 G290 M291 R301 M302 G303 T305 F306 M309 G51 G53 S54 S55 I75 E76 S77 S78 G83 G84 C148 V149 T212 T213 G214 H215 F219 F222 G268 M269 R279 M280 G281 T283 F284 M287 P32318 26919468 VTHCLSDIVKKEDWSDFKFAPIRESTVSRAMTSRYFKDLDKFAVSDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQLFSAMVMRKPAHLFLQELEIPYEDEGDYVVVKHAALFISTVLSKVLQLPNVKLFNATCVEDLVTRPPTEKGEVTVAGVVTNWTLVTQAHGTCSMDPNVIELAGYKNDGTRDLSQKHGVILSTTGHDGPFGAFCAKRIVDIDQNQKLGGMKGLDMNHAEHDVVIHSGAYAGVDNMYFAGMEVAELDGLNRMGPTFGAMALSGVHAAEQILKHFA 4y4m A 2.71 BS01 48F A 1 V42 G43 G45 P46 S47 E66 R67 H68 G73 G74 I136 V138 A178 T179 G180 S184 G229 M230 M241 G242 F245 M248 V38 G39 G41 P42 S43 E62 R63 H64 G69 G70 I132 V134 A174 T175 G176 S180 G225 M226 M237 G238 F241 M244 5.3.1.29 Q58018 26919468 MNIKDIKLNADETKTTKAILKASFDMWLDIVEADVVIVGAGPSGLTCARYLAKEGFKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADELLREVGIKLIDMGDGYYVADSVEVPAKLAVAAMDAGAKILTGIVVEDLILREDGVAGVVINSYAIERAGLHIDPLTIRSKVVVDATGHEASIVNILVKKNKLEADVPGEKSMWAEKGENALLRNTREVYPNLFVCGMAANASHGGYRMGAIFGGMYLSGKLCAELITEKLK 4y4m A 2.71 BS02 48F G 1 H164 D166 H160 D162 5.3.1.29 Q58018 26919468 MNIKDIKLNADETKTTKAILKASFDMWLDIVEADVVIVGAGPSGLTCARYLAKEGFKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADELLREVGIKLIDMGDGYYVADSVEVPAKLAVAAMDAGAKILTGIVVEDLILREDGVAGVVINSYAIERAGLHIDPLTIRSKVVVDATGHEASIVNILVKKNKLEADVPGEKSMWAEKGENALLRNTREVYPNLFVCGMAANASHGGYRMGAIFGGMYLSGKLCAELITEKLK 4y4n A 2.10 BS01 48H A 1 V35 G36 G38 P39 S40 L58 E59 R60 H61 G66 G67 I131 V132 V133 A173 T174 G175 H176 S179 G225 M226 R236 M237 G238 F241 M244 V32 G33 G35 P36 S37 L55 E56 R57 H58 G63 G64 I128 V129 V130 A170 T171 G172 H173 S176 G222 M223 R233 M234 G235 F238 M241 5.3.1.29 F6BCS4 26919468 RLRADEYATTRAILKSAFDMWLDIIDVDVAIVGGGPSGLTAARYIAKEGYKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADEILREVGVKLEKVEGEDGLYTADSVEVPAKLAVGAIDAGAKVLTGIVVEDLVLRENRVAGVVINSYAIEKAGLHIDPITITAKYVVDATGHDASVVTTLSRKNPELGLEVPGEKSMWAEKGENALLRNTREVYPGLFVCGMAANAVYAGHRMGAIFGGMYISGKKCAEMIVEKLKNN 4y9d A 2.01 BS01 NAI A 1 G13 A15 S16 G17 A18 D37 V38 R39 L62 D63 I64 A92 V94 G11 A13 S14 G15 A16 D35 V36 R37 L60 D61 I62 A90 V92 G2IN91 DFQDQVAFITGGASGAGFGQAKVFGQAGAKIVVADVRAEAVEKAVAELEGLGITAHGIVLDIMDREAYARAADEVEAVFGQAPTLLSNTAGVNSFGPIEKTTYDDFDWIIGVNLNGVINGMVTFVPRMIASGRPGHIVTVSSLGGFMGSALAGPYSAAKAASINLMEGYRQGLEKYGIGVSVCTPANIHGLEPEKLAEAIKKGVEDNALYIIPYPEVREGLEKHFQAIIDSVAPM 4y9p A 2.44 BS01 CA A 1 I99 E135 I97 E133 Q9HXH7 RVASPSSELRRALEANEFIPYYQPLSPGQGGRWIGVEVLMRWRHPREGLIRPDLFIPFAERSGLIVPMTRALMRQVAEDLGGHAGKLEPGFHIGFNISATHCHELALVDDCRELLAAFPPGHITLVLELTERELIESSEVTDRLFDELHALGVKIAIDDFGTRKFQVDCLKIDQSFVARIGIDTLSGHILDSIVELSAKLDLDIVAEGVETPEQRDYLAARGVDYLQGYLIGRPMPLESLLSSLTVQEGQG 4y9p A 2.44 BS02 CA A 2 D161 D183 Q184 E217 D159 D173 Q174 E207 Q9HXH7 RVASPSSELRRALEANEFIPYYQPLSPGQGGRWIGVEVLMRWRHPREGLIRPDLFIPFAERSGLIVPMTRALMRQVAEDLGGHAGKLEPGFHIGFNISATHCHELALVDDCRELLAAFPPGHITLVLELTERELIESSEVTDRLFDELHALGVKIAIDDFGTRKFQVDCLKIDQSFVARIGIDTLSGHILDSIVELSAKLDLDIVAEGVETPEQRDYLAARGVDYLQGYLIGRPMPLESLLSSLTVQEGQG 4y9p A 2.44 BS03 CA A 3 E39 N98 E130 D160 E37 N96 E128 D158 Q9HXH7 RVASPSSELRRALEANEFIPYYQPLSPGQGGRWIGVEVLMRWRHPREGLIRPDLFIPFAERSGLIVPMTRALMRQVAEDLGGHAGKLEPGFHIGFNISATHCHELALVDDCRELLAAFPPGHITLVLELTERELIESSEVTDRLFDELHALGVKIAIDDFGTRKFQVDCLKIDQSFVARIGIDTLSGHILDSIVELSAKLDLDIVAEGVETPEQRDYLAARGVDYLQGYLIGRPMPLESLLSSLTVQEGQG 4y9p A 2.44 BS04 C2E A 1 Q25 E39 L41 M42 R43 R53 P54 D55 N98 D160 D161 Q184 E217 G218 E220 G238 Y239 P244 Q23 E37 L39 M40 R41 R51 P52 D53 N96 D158 D159 Q174 E207 G208 E210 G228 Y229 P234 Q9HXH7 RVASPSSELRRALEANEFIPYYQPLSPGQGGRWIGVEVLMRWRHPREGLIRPDLFIPFAERSGLIVPMTRALMRQVAEDLGGHAGKLEPGFHIGFNISATHCHELALVDDCRELLAAFPPGHITLVLELTERELIESSEVTDRLFDELHALGVKIAIDDFGTRKFQVDCLKIDQSFVARIGIDTLSGHILDSIVELSAKLDLDIVAEGVETPEQRDYLAARGVDYLQGYLIGRPMPLESLLSSLTVQEGQG 4y9p B 2.44 BS04 C2E B 1 Q25 E39 L41 M42 R43 P54 D55 L74 N98 D160 D161 Q184 G218 E220 G238 Y239 P244 Q21 E35 L37 M38 R39 P50 D51 L70 N94 D156 D157 Q175 G209 E211 G229 Y230 P235 Q9HXH7 ASPSSELRRALEANEFIPYYQPLSPGQGGRWIGVEVLMRWRHPREGLIRPDLFIPFAERSGLIVPMTRALMRQVAEDLGGHAGKLEPGFHIGFNISATHCHELALVDDCRELLAAFPPGHITLVLELTERELIESSEVTDRLFDELHALGVKIAIDDFGTAYLRKFQVDCLKIDQSFVARIGIDTLSGHILDSIVELSAKLDLDIVAEGVETPEQRDYLAARGVDYLQGYLIGRPMPLESLLSSLTVQEGQG 4y9q A 1.77 BS02 MG A 1 V40 F97 N98 V36 F93 N94 Q9HXH7 ASPSSELRRALEANEFIPYYQPLSPGQGGRWIGVEVLMRWRHPREGLIRPDLFIPFAERSGLIVPMTRALMRQVAEDLGGHAGKLEPGFHIGFNISATHCHELALVDDCRELLAAFPPGHITLVLELTERELIESSEVTDRLFDELHALGVKIAIDDFGTGHSSLAYLRKFQVDCLKIDQSFVARIGIDTLSGHILDSIVELSAKLDLDIVAEGVETPEQRDYLAARGVDYLQGYLIGRPMPLESLLSSLTVQEGQ 4yac A 1.70 BS01 NAI A 1 G13 G15 S16 G17 V18 D38 I39 R40 H43 L63 D64 L65 V94 V114 G13 G15 S16 G17 V18 D38 I39 R40 H43 L63 D64 L65 V94 V114 C0SUK3 MQDLEGKVAFVTGGGSGVALGQAKVLAEEAQMKVVIADIRQDHLDEAMGYFSQKNVAVHPVRLDLTDRAAYAAAVDEAEQVFGPVDLLCNTAGVSQFGPIEKATFDDWDWQMDVNVNGVINGVMTVMPRMIERGQGGHILITASMSAFVALPTTGIYCTTKYAVRGLAESLRVEMPKYNIGVSLLCPGGEAVFAGLKRVIEHGFDPVDLGRVVLDAVRNDRFWVLPYPEFAEGQKARDQEVIDAMMSYADHPDYARRMKIREQMKRDMPG 4yaf A 1.91 BS03 2AM A 1 G534 C566 S596 R597 K602 Y604 Q606 M636 D639 G465 C497 S527 R528 K533 Y535 Q537 M567 D570 1.6.2.4 P00388 APPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEASSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPARALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 4yag A 1.50 BS01 NAI A 1 G12 S15 G16 I17 D36 I37 R38 H41 L63 D64 V65 N91 A92 G93 I94 I114 T142 A143 S144 Y158 K162 P188 G189 P190 I191 S193 R194 I195 N201 G12 S15 G16 I17 D36 I37 R38 H41 L63 D64 V65 N91 A92 G93 I94 I114 T142 A143 S144 Y158 K162 P188 G189 P190 I191 S193 R194 I195 N201 C0SUJ9 MDIAGTTAFITGGASGIGFGIAQRLLANGARLVLADIRQDHLDEARQFFEERQQGRNVHTIRLDVSDRAQMAEAARECEAVMGGPDILINNAGIDPSGPFKDATYQDWDYGLAINLMGPINGIMAFTPGMRARGRGGHIVNTASLAGLTPMPSFMAIYATAKAAVITLTETIRDSMAEDNIGVTVLMPGPIKSRIHESGQNRPERFRAGSGLAETEQQLAKRVVADNWMEPTEVGDMIVDAIVHNKLYVSTHGNWRETCEARFQALLDSMP 4yai B 1.60 BS02 GGE B 1 D95 S144 A146 T149 M151 M155 Y158 P188 G189 I195 R222 W228 W255 D95 S144 A146 T149 M151 M155 Y158 P188 G189 I195 R222 W228 W255 C0SUJ9 MDIAGTTAFITGGASGIGFGIAQRLLANGARLVLADIRQDHLDEARQFFEERQQGRNVHTIRLDVSDRAQMAEAARECEAVMGGPDILINNAGIDPSGPFKDATYQDWDYGLAINLMGPINGIMAFTPGMRARGRGGHIVNTASLAGLTPMPSFMAIYATAKAAVITLTETIRDSMAEDNIGVTVLMPGPIKSRIHESGQNRPERFRAGSGLAETEQQLAKRVVADNWMEPTEVGDMIVDAIVHNKLYVSTHGNWRETCEARFQALLDSMPEA 4yav A 1.40 BS01 GAZ A 1 I12 C15 F17 I39 T55 A56 L57 P58 E70 S71 S109 G110 Y113 L117 Y217 N223 I9 C12 F14 I36 T52 A53 L54 P55 E67 S68 S106 G107 Y110 L114 Y214 N220 G2IN94 PQELTIYHIPGCPFSERVEIMLELKGLRMKDVEIDISKPRPDWLLAKTGGTTALPLLDVENGESLKESMVILRYLEQRYPEPAVAHPDPFCHAVEGMLAELAGPFSGAGYRMILNREIGKREEMRAAVDAEFGKVDAFLKRYATGSDFLFDDRFGWAEVAFTPMFKRLWFLDYYEDYEVPANFDRVLRWRAACTAHPAAQYRSKEELLKLYYDYTQGGGNGRIPEGRSISSFSPDVDWRTRPMPPRDKWGHAATDAELGLTR 4yb4 A 2.50 BS01 MG A 1 R98 D228 D232 R97 D227 D231 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb4 A 2.50 BS02 48Y A 1 S72 R85 R88 R98 R118 Y125 D228 S71 R84 R87 R97 R117 Y124 D227 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb4 A 2.50 BS03 NAI A 1 I13 F67 A69 A70 T71 S72 L241 G242 E257 H260 G261 S262 A263 P264 D265 I266 N273 D313 I12 F66 A68 A69 T70 S71 L240 G241 E256 H259 G260 S261 A262 P263 D264 I265 N272 D312 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb4 A 2.50 BS04 48Y B 1 K171 N173 V174 D204 K170 N172 V173 D203 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb4 A 2.50 BS05 NAI B 1 N173 I202 N205 N172 I201 N204 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb4 B 2.50 BS03 MG A 2 R98 D228 R97 D227 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb4 B 2.50 BS05 NAI B 1 I13 F67 A70 T71 S72 I84 L241 G242 E257 V259 H260 G261 S262 A263 P264 D265 I266 N273 D313 I12 F66 A69 T70 S71 I83 L240 G241 E256 V258 H259 G260 S261 A262 P263 D264 I265 N272 D312 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb4 C 2.50 BS03 NAI C 1 I13 A69 A70 T71 S72 L241 G242 E257 V259 H260 G261 S262 A263 P264 D265 I266 N273 I12 A68 A69 T70 S71 L240 G241 E256 V258 H259 G260 S261 A262 P263 D264 I265 N272 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb4 C 2.50 BS05 NAI D 1 N173 I202 N205 M208 N172 I201 N204 M207 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb4 D 2.50 BS05 NAI D 1 I13 F67 A70 T71 S72 I84 L241 E257 V259 H260 G261 S262 A263 P264 D265 I266 N273 I12 F66 A69 T70 S71 I83 L240 E256 V258 H259 G260 S261 A262 P263 D264 I265 N272 1.1.1.87 Q72IW9 AYRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRPVPGSRPGVDLVIVRENTEGLYVEQERRYLDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALKSL 4yb5 A 2.24 BS01 HIS A 1 Y228 G247 V248 E249 R250 T252 H266 M267 V268 Y220 G239 V240 E241 R242 T244 H258 M259 V260 2.4.2.17 Q5HSJ4 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb5 A 2.24 BS02 HIS D 1 M230 H232 S288 L290 M222 H224 S280 L282 2.4.2.17 Q5HSJ4 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb5 D 2.24 BS02 HIS E 1 H232 S288 L290 H225 S281 L283 2.4.2.17 Q5HSJ4 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQEQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 A 1.98 BS01 AMP A 1 C104 L170 V171 S172 S173 G174 A175 T176 C101 L167 V168 S169 S170 G171 A172 T173 2.4.2.17 Q5HSJ4 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 A 1.98 BS03 MG A 1 D56 E83 D53 E80 2.4.2.17 Q5HSJ4 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 B 1.98 BS01 AMP B 1 C104 L170 S172 S173 G174 T176 C101 L161 S163 S164 G165 T167 2.4.2.17 Q5HSJ4 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 B 1.98 BS03 HIS F 1 H232 L256 S288 L290 H223 L247 S279 L281 2.4.2.17 Q5HSJ4 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 C 1.98 BS02 AMP C 1 C104 L170 S172 S173 G174 A175 T176 C100 L166 S168 S169 G170 A171 T172 2.4.2.17 Q5HSJ4 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 C 1.98 BS03 HIS C 1 Y228 G247 V248 E249 R250 T252 H266 V268 Y224 G243 V244 E245 R246 T248 H262 V264 2.4.2.17 Q5HSJ4 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 D 1.98 BS03 HIS E 1 M230 H232 L256 S288 L290 M226 H228 L252 S284 L286 2.4.2.17 Q5HSJ4 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb6 E 1.98 BS05 MG E 2 A223 E225 S226 K227 I294 A217 E219 S220 K221 I288 2.4.2.17 Q5HSJ4 NTRLRIAIQKSGRLSKESIELLSECGVKMHISLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb7 B 2.20 BS01 MG B 1 R54 D55 D56 R51 D52 D53 2.4.2.17 Q5HSJ4 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb7 B 2.20 BS02 ATP B 1 Q12 G15 R16 L17 R54 D55 D56 G73 N75 V76 G102 Y103 C104 S172 Q9 G12 R13 L14 R51 D52 D53 G70 N72 V73 G99 Y100 C101 S169 2.4.2.17 Q5HSJ4 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb7 C 2.20 BS01 MG C 1 D55 D56 D52 D53 2.4.2.17 Q5HSJ4 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb7 C 2.20 BS02 ATP C 1 Q12 G15 R16 R54 D55 D56 N75 V76 C104 L170 S172 Q9 G12 R13 R51 D52 D53 N72 V73 C101 L167 S169 2.4.2.17 Q5HSJ4 NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb7 E 2.20 BS02 ATP E 1 Q12 G15 R16 L17 R54 D55 D56 G73 N75 V76 C104 L170 S172 Q8 G11 R12 L13 R50 D51 D52 G69 N71 V72 C100 L166 S168 2.4.2.17 Q5HSJ4 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4yb7 G 2.20 BS02 ATP G 1 Q12 G15 R16 D55 D56 G73 N75 V76 Y103 C104 L170 S172 Q8 G11 R12 D51 D52 G69 N71 V72 Y99 C100 L166 S168 2.4.2.17 Q5HSJ4 TRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK 4ydd A 1.86 BS01 SF4 A 1 H32 V34 C36 G38 A39 C40 H42 G73 C74 G77 P210 H28 V30 C32 G34 A35 C36 H38 G69 C70 G73 P206 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 4ydd A 1.86 BS02 MO A 1 D170 G459 H770 D166 G455 H766 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 4ydd A 1.86 BS03 MGD A 1 K76 D170 W200 G201 S202 N203 Q206 T207 R208 I209 I228 S229 P230 D231 N233 G248 D250 G421 G422 G423 T424 W427 I458 G459 N761 P763 H764 S765 R766 S768 V769 H770 R830 H835 R882 K72 D166 W196 G197 S198 N199 Q202 T203 R204 I205 I224 S225 P226 D227 N229 G244 D246 G417 G418 G419 T420 W423 I454 G455 N757 P759 H760 S761 R762 S764 V765 H766 R826 H831 R878 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 4ydd A 1.86 BS04 MD1 A 1 L33 N35 Y168 D170 H426 Y536 R537 G538 N539 Q543 I564 N565 I566 R567 D569 S581 W584 K587 D615 S762 H764 V769 H770 S771 T772 H835 Q849 C852 Q881 R882 L29 N31 Y164 D166 H422 Y532 R533 G534 N535 Q539 I560 N561 I562 R563 D565 S577 W580 K583 D611 S758 H760 V765 H766 S767 T768 H831 Q845 C848 Q877 R878 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 4ydd B 1.86 BS01 F3S B 1 C149 P150 N151 I154 I165 C170 K171 G172 A173 Q174 A175 C176 A194 C145 P146 N147 I150 I161 C166 K167 G168 A169 Q170 A171 C172 A190 G8QM54 MKAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 4ydd B 1.86 BS02 SF4 B 1 C137 N138 C140 P143 A144 C145 C180 Y182 P185 K196 C133 N134 C136 P139 A140 C141 C176 Y178 P181 K192 G8QM54 MKAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 4ydd B 1.86 BS03 SF4 B 2 C21 I22 G23 C24 Q25 C27 R47 V49 P134 C216 V217 G218 C17 I18 G19 C20 Q21 C23 R43 V45 P130 C212 V213 G214 G8QM54 MKAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 4ydd B 1.86 BS04 SF4 B 3 Y14 C31 W35 W46 R47 M136 C197 I198 G199 C200 P210 C212 Y10 C27 W31 W42 R43 M132 C193 I194 G195 C196 P206 C208 G8QM54 MKAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 4ydd C 1.86 BS01 SF4 C 1 H32 C36 G38 A39 C40 H42 G73 C74 G77 P210 H25 C29 G31 A32 C33 H35 G66 C67 G70 P203 G8QM55 AFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 4ydd C 1.86 BS02 MO C 1 D170 G459 D163 G452 G8QM55 AFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 4ydd D 1.86 BS01 F3S D 1 C149 P150 N151 C170 K171 G172 A173 Q174 A175 C176 A194 C144 P145 N146 C165 K166 G167 A168 Q169 A170 C171 A189 G8QM54 KAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 4ydd D 1.86 BS02 SF4 D 1 C137 N138 H139 C140 C145 V163 C180 P185 K196 C132 N133 H134 C135 C140 V158 C175 P180 K191 G8QM54 KAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 4ydd E 1.86 BS01 SF4 E 1 H32 C36 G38 A39 C40 H42 G73 C74 G77 H25 C29 G31 A32 C33 H35 G66 C67 G70 G8QM55 AFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 4ydd F 1.86 BS02 SF4 F 1 C137 N138 H139 C140 A144 C145 C180 Y182 P185 K196 C132 N133 H134 C135 A139 C140 C175 Y177 P180 K191 G8QM54 KAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 4yej A 1.40 BS01 RAM A 1 G211 H212 Q242 F247 G99 H100 Q130 F135 Q9AYY6 QFRAIIESPEGAGHVGYQYRRNTGSTMRMVSDVLDERVSLWDFHCDPSGNVIQPGPNVDSRQYLQAAIDYVSSNGGGTITIPAGYTWYLGSYGVGGIAGHSGIIQLRSNVNLNIEGRIHLSPFFDLKPFQVFVGFDNGDPASSGNLENCHIYGHGVVDFGGYEFGASSQLRNGVAFGRSYNCSVTGITFQNGDVTWAITLGWNGYGSNCYVRKCRFINLVNSSVNAAHSTVYVNCPYSGVESCYFSMSSSFARNIACSVQLHQHDTFYRGSTVNGYCRGAYVVMHAAEAAGAGSYAYNMQVENNIAVIYGQFVILGSDVTATVSGHLNDVIVSGNIVSIGERAAFSAPFGAFIDIGPDNSGASNVQDIQRVLVTGNSFYAPANITDSAAITLRANLNGCTFIANNFDCRYMVYNAPGTTSPVVQNLVWDKSNVIGGTHANQRAGQNLFDMQFASVVNSTIEVQLSCEDLSMFSCILFPASCQLSYSKITVDSAWTKSMSNTAVFEGNQQAGANVYVSYPATVNLTSYNTQGAVPFFSTDTNYAWVTSAYSLSINENLDFSPPATYTNKANGQLVGVGYNEIGGVRSVSVRLMLQRQV 4yhx A 2.15 BS01 NUC B 1 E19 K31 S32 S33 E39 V65 S69 G70 K77 T79 R80 F81 H119 L120 G182 E183 G184 C185 F187 I191 T208 Q209 H210 K234 F237 W239 E241 K267 K299 N303 K304 E16 K28 S29 S30 E36 V62 S66 G67 K74 T76 R77 F78 H116 L117 G169 E170 G171 C172 F174 I178 T195 Q196 H197 K221 F224 W226 E228 K254 K286 N290 K291 C7SQG1 NESINPWVLTGFADAEGSFILRIRNNNKSSAGYSTELGFQITLHKKDKSILENIQSTWKVGVIANSGDNAVSLKVTRFEDLRVVLNHFEKYPLITQKLGDYLLFKQAFSVMENKEHLKIEGIKRLVGIKANLNWGLTDELKEAFVASGGENIFNKNIPNSGWLAGFTSGEGCFFVSLIKSKSKLGVQVQLVFSITQHARDRELMDNLVTYLGCGYIKEKKKSEFSWLEFVVTKFSDIKDKIIPVFQENNIIGVKLEDFEDWCKVAKLIEEKKHLTESGLEEIRNIKLNMNKGRV 4yhx A 2.15 BS02 NUC C 1 A18 E19 G20 S21 I23 R25 R27 Q43 T45 L46 H47 A73 K77 N136 W137 K194 S195 K196 Q200 Q202 Y228 K230 K232 K234 W239 T245 K246 F247 H286 A15 E16 G17 S18 I20 R22 R24 Q40 T42 L43 H44 A70 K74 N133 W134 K181 S182 K183 Q187 Q189 Y215 K217 K219 K221 W226 T232 K233 F234 H273 C7SQG1 NESINPWVLTGFADAEGSFILRIRNNNKSSAGYSTELGFQITLHKKDKSILENIQSTWKVGVIANSGDNAVSLKVTRFEDLRVVLNHFEKYPLITQKLGDYLLFKQAFSVMENKEHLKIEGIKRLVGIKANLNWGLTDELKEAFVASGGENIFNKNIPNSGWLAGFTSGEGCFFVSLIKSKSKLGVQVQLVFSITQHARDRELMDNLVTYLGCGYIKEKKKSEFSWLEFVVTKFSDIKDKIIPVFQENNIIGVKLEDFEDWCKVAKLIEEKKHLTESGLEEIRNIKLNMNKGRV 4yhx A 2.15 BS03 CA A 1 A18 E183 A15 E170 C7SQG1 NESINPWVLTGFADAEGSFILRIRNNNKSSAGYSTELGFQITLHKKDKSILENIQSTWKVGVIANSGDNAVSLKVTRFEDLRVVLNHFEKYPLITQKLGDYLLFKQAFSVMENKEHLKIEGIKRLVGIKANLNWGLTDELKEAFVASGGENIFNKNIPNSGWLAGFTSGEGCFFVSLIKSKSKLGVQVQLVFSITQHARDRELMDNLVTYLGCGYIKEKKKSEFSWLEFVVTKFSDIKDKIIPVFQENNIIGVKLEDFEDWCKVAKLIEEKKHLTESGLEEIRNIKLNMNKGRV 4yhx A 2.15 BS04 CA A 2 E19 G182 E183 E16 G169 E170 C7SQG1 NESINPWVLTGFADAEGSFILRIRNNNKSSAGYSTELGFQITLHKKDKSILENIQSTWKVGVIANSGDNAVSLKVTRFEDLRVVLNHFEKYPLITQKLGDYLLFKQAFSVMENKEHLKIEGIKRLVGIKANLNWGLTDELKEAFVASGGENIFNKNIPNSGWLAGFTSGEGCFFVSLIKSKSKLGVQVQLVFSITQHARDRELMDNLVTYLGCGYIKEKKKSEFSWLEFVVTKFSDIKDKIIPVFQENNIIGVKLEDFEDWCKVAKLIEEKKHLTESGLEEIRNIKLNMNKGRV 4yhx A 2.15 BS05 CA A 3 E19 G182 E16 G169 C7SQG1 NESINPWVLTGFADAEGSFILRIRNNNKSSAGYSTELGFQITLHKKDKSILENIQSTWKVGVIANSGDNAVSLKVTRFEDLRVVLNHFEKYPLITQKLGDYLLFKQAFSVMENKEHLKIEGIKRLVGIKANLNWGLTDELKEAFVASGGENIFNKNIPNSGWLAGFTSGEGCFFVSLIKSKSKLGVQVQLVFSITQHARDRELMDNLVTYLGCGYIKEKKKSEFSWLEFVVTKFSDIKDKIIPVFQENNIIGVKLEDFEDWCKVAKLIEEKKHLTESGLEEIRNIKLNMNKGRV 4yj5 B 2.41 BS04 FBP B 1 L431 T432 K433 S434 S437 W482 R489 G514 R516 P517 S519 G520 F521 T522 L418 T419 K420 S421 S424 W469 R476 G501 R503 P504 S506 G507 F508 T509 2.7.1.40 P14618 QTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYYLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4yj5 D 2.41 BS02 MG D 1 N75 S77 D113 T114 E118 S243 N62 S64 D100 T101 E105 S230 2.7.1.40 P14618 QTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYYLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4yje A 1.90 BS01 III B 1 F458 M503 T506 N507 F510 G511 K516 R549 N550 W553 S590 W593 N594 A597 N641 N679 M717 F56 M101 T104 N105 F108 G109 K114 R147 N148 W151 S188 W191 N192 A195 N239 N277 M315 P25054 HHHMLHLLEQIRAYCETCWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYK 4yjl A 2.10 BS01 III G 1 F458 R463 M503 T506 N507 F510 G511 K516 D539 Q542 V543 R549 N550 W553 S583 S590 W593 N594 A597 K603 R640 N641 N679 W685 N686 M717 M720 F59 R64 M104 T107 N108 F111 G112 K117 D140 Q143 V144 R150 N151 W154 S184 S191 W194 N195 A198 K204 R241 N242 N280 W286 N287 M318 M321 P25054 HHHHHHMLHLLEQIRAYCETCWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAK 4yk6 A 1.70 BS01 III B 1 F458 R463 M503 T506 N507 F510 G511 K516 Q542 R549 N550 W553 R554 K586 S590 W593 N594 A597 H598 N641 F56 R61 M101 T104 N105 F108 G109 K114 Q140 R147 N148 W151 R152 K184 S188 W191 N192 A195 H196 N239 P25054 HHHMLHLLEQIRAYCETCWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDAN 4ykm A 1.58 BS01 RET A 1 F15 W32 A36 Q39 I52 V54 T56 Y59 I63 V76 W109 K111 L121 Q132 F15 W32 A36 Q39 I52 V54 T56 Y59 I63 V76 W109 K111 L121 Q132 P29373 PNQSGNWKIIRSENFEELLKVLGVNVMLRKIWVAAASKQAVEIKQEGDTFYIKVSTTVYTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTKELTNDGELILTMTADDVVCTQVFVRE 4ykm B 1.58 BS01 RET B 1 F15 W32 A36 I52 V54 T56 Y59 I63 V76 W109 K111 L121 F15 W32 A36 I52 V54 T56 Y59 I63 V76 W109 K111 L121 P29373 PNQSGNWKIIRSENFEELLKVLGVNVMLRKIWVAAASKQAVEIKQEGDTFYIKVSTTVYTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTKELTNDGELILTMTADDVVCTQVFVRE 4yko A 1.57 BS01 RET A 1 Y32 A36 I52 V54 T56 Y59 I63 V76 W109 K111 L121 M123 Y32 A36 I52 V54 T56 Y59 I63 V76 W109 K111 L121 M123 P29373 PNQSGNWKIIRSENFEELLKVLGVNVMLRKIYVAAASKQAVEIKQEGDTFYIKVSTTVYTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTKELTNDGELILTMTADDVVCTQVFVRE 4yko B 1.57 BS01 RET B 1 F15 Y32 A36 I52 V54 T56 Y59 I63 V76 W109 K111 L121 M123 Q132 F15 Y32 A36 I52 V54 T56 Y59 I63 V76 W109 K111 L121 M123 Q132 P29373 PNQSGNWKIIRSENFEELLKVLGVNVMLRKIYVAAASKQAVEIKQEGDTFYIKVSTTVYTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTKELTNDGELILTMTADDVVCTQVFVRE 4ykq A 1.91 BS01 4EO A 1 N51 S52 D54 A55 K58 D93 I96 G97 M98 L107 F138 T184 V186 N36 S37 D39 A40 K43 D78 I81 G82 M83 L92 F123 T169 V171 P07900 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 4yku A 1.70 BS01 4ER A 1 N51 S52 A55 D93 G97 M98 L107 T109 F138 T184 N36 S37 A40 D78 G82 M83 L92 T94 F123 T169 P07900 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 4ykw A 1.85 BS01 4ES A 1 A55 D93 I96 G97 M98 N106 L107 G135 V136 F138 Y139 T184 A45 D83 I86 G87 M88 N96 L97 G125 V126 F128 Y129 T174 P07900 PMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 4ykx A 1.80 BS01 4ET A 1 N51 S52 A55 K58 D93 I96 G97 M98 F138 T184 V186 N36 S37 A40 K43 D78 I81 G82 M83 F123 T169 V171 P07900 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 4ykz A 1.85 BS01 4EV A 1 L48 N51 S52 D54 A55 K58 D93 I96 G97 M98 T184 V186 L33 N36 S37 D39 A40 K43 D78 I81 G82 M83 T169 V171 P07900 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 4ylw A 1.79 BS01 52Y A 1 Y38 L42 L46 L58 A59 F62 T63 L67 L68 P69 I94 F98 L359 P364 Y6 L10 L14 L26 A27 F30 T31 L35 L36 P37 I62 F66 L327 P332 1.3.5.2 Q02127 GDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR 4ymi A 1.70 BS01 NAP A 1 M12 G13 G14 T15 F16 H20 H23 T44 T88 Y89 T90 F108 T110 G111 W121 E122 V136 R138 S169 S170 M7 G8 G9 T10 F11 H15 H18 T39 T78 Y79 T80 F98 T100 G101 W111 E112 V126 R128 S144 S145 2.7.7.18 B1MMZ4 RRRLGVMGGTFDPIHNGHLVAASEVADRFALDEVIFVPTGQPRKVSPAEHRYLMTVIATASNPRFTVSRADIDRGGATYTVDTLTDLRTAHPDADLYFITGADALASILSWENWEQLFTLAKFIGVSRPGYGLSLVEVPALAISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYSG 4ymi A 1.70 BS02 ADE A 1 S71 N72 P73 S61 N62 P63 2.7.7.18 B1MMZ4 RRRLGVMGGTFDPIHNGHLVAASEVADRFALDEVIFVPTGQPRKVSPAEHRYLMTVIATASNPRFTVSRADIDRGGATYTVDTLTDLRTAHPDADLYFITGADALASILSWENWEQLFTLAKFIGVSRPGYGLSLVEVPALAISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYSG 4ymi B 1.70 BS02 NAP B 1 M12 G13 G14 T15 F16 H20 H23 T44 W48 T88 T90 F108 T110 G111 A114 S117 I118 E122 V136 R138 S169 S170 M8 G9 G10 T11 F12 H16 H19 T40 W44 T83 T85 F103 T105 G106 A109 S112 I113 E117 V131 R133 S164 S165 2.7.7.18 B1MMZ4 ERRRLGVMGGTFDPIHNGHLVAASEVADRFALDEVIFVPTGQPWQKQRKVSPAEHRYLMTVIATASNPRFTVSRADIDRGGATYTVDTLTDLRTAHPDADLYFITGADALASILSWENWEQLFTLAKFIGVSRPGYELSSDHIAHAELPPDGLSLVEVPALAISSTDCRIRAGQARPIWYLVPDGVVQYVAKHRLYSG 4ymm A 2.20 BS01 NUC T 1 H34 R40 S229 K230 G231 E232 T233 K234 Y271 Y296 H28 R34 S221 K222 G223 E224 T225 K226 Y263 Y288 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4ymn A 2.59 BS01 NUC T 1 H34 Y36 N37 R40 S229 K230 G231 E232 T233 K234 Y271 E295 Y296 H28 Y30 N31 R34 S221 K222 G223 E224 T225 K226 Y263 E287 Y288 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4ymn A 2.59 BS04 0KX A 1 R149 S180 R183 S188 G189 D190 Y271 G274 D276 R143 S174 R177 S182 G183 D184 Y263 G266 D268 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4yn4 A 2.24 BS01 NUC T 1 I33 H34 N37 S229 K230 G231 E232 T233 K234 Y271 Y296 I27 H28 N31 S221 K222 G223 E224 T225 K226 Y263 Y288 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4yr6 A 2.38 BS01 III C 1 H52 L54 N56 G58 F60 T102 T103 T104 T105 S106 H52 L54 N56 G58 F60 T102 T103 T104 T105 S106 QVTLKESGPGILQPSQTLSLTCSFSGFSLSTSNMGVVWIRQPSGKGLEWLLHILWNDGKFYNPALKSRLTISKDTYNNQVFLKIANVDTADTATYYCARLFTTTTSGYFDVWGAGTTVTVSSAKTTPPSVYPLAPNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIAA 4yr6 B 2.38 BS01 III C 1 Y30 Y32 F91 W92 D93 T94 W96 Y30 Y32 F91 W92 D93 T94 W96 DIQMTQSPASLSASVGETVTITCRASGNIYNYLAWYQQKQGKSPQLLVYNAKTLADGVPSRFSGSGSGTQYSLKINSLQPEDFGSYFCQHFWDTPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 4yr6 D 2.38 BS01 III F 1 H52 L54 W55 N56 G58 F60 T102 T103 T104 S106 H52 L54 W55 N56 G58 F60 T102 T103 T104 S106 QVTLKESGPGILQPSQTLSLTCSFSGFSLSTSNMGVVWIRQPSGKGLEWLLHILWNDGKFYNPALKSRLTISKDTYNNQVFLKIANVDTADTATYYCARLFTTTTSGYFDVWGAGTTVTVSSAKTTPPSVYPLAPMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIAA 4yyy B 2.43 BS01 URI B 1 T87 L117 G118 Y168 R171 I183 S186 I187 K190 T87 L117 G118 Y168 R171 I183 S186 I187 K190 2.4.2.4 Q7CP66 26919527 MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITGSILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGQLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPSDFVENYDKYLPTAMLSKAVYADTEGFISAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDSIDGQRPLAVIHAKDEASWQEAAKAVKAAIILDDKAPASTPSVYRRITE 4yyy B 2.43 BS02 URI B 2 S248 Q261 Y267 S248 Q261 Y267 2.4.2.4 Q7CP66 26919527 MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITGSILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGQLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPSDFVENYDKYLPTAMLSKAVYADTEGFISAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDSIDGQRPLAVIHAKDEASWQEAAKAVKAAIILDDKAPASTPSVYRRITE 4z1c A 1.93 BS01 CD A 1 C18 H204 E241 D252 C9 H195 E222 D233 2.5.1.55 P56060 26649906 KSVLIAGPCVIESLENLRSIATKLQPLANNERLDFYFKASFDKANRTSLESYRGPGLEKGLEMLQTIKEEFGYKILTDVHESYQASVAAKVADILQIPAFLCRQTDLIVEVSQTNAIVNIKKGQFMNPKDMQYSVLKALKTRDKSIQSPTYETALKNGVWLCERGSSFGYGNLVVDMRSLKIMREFAPVIFDATHSVQMPSSFAPILARAAAAVGIDGLFAETHVDPKNALSDGANMLKPDELEQLVTDMLKIQNLF 4z1d A 1.65 BS01 PEP A 1 K47 S49 K52 Q105 P107 A108 K130 R173 H204 F239 K38 S40 K43 Q96 P98 A99 K121 R164 H195 F219 2.5.1.55 P56060 26649906 KSVLIAGPCVIESLENLRSIATKLQPLANNERLDFYFKASFDKANRTSLESYRGPGLEKGLEMLQTIKEEFGYKILTDVHESYQASVAAKVADILQIPAFLCRQTDLIVEVSQTNAIVNIKKGQFMNPKDMQYSVLKALKTRDKSIQSPTYETALKNGVWLCERGSSFGYGNLVVDMRSLKIMREFAPVIFDATHSVQMPSFAPILARAAAAVGIDGLFAETHVDPKNALSDGANMLKPDELEQLVTDMLKIQNLF 4z1d B 1.65 BS02 ZN B 1 C18 T203 H204 E241 D252 C9 T194 H195 E221 D232 2.5.1.55 P56060 26649906 KSVLIAGPCVIESLENLRSIATKLQPLANNERLDFYFKASFDKANRTSLESYRGPGLEKGLEMLQTIKEEFGYKILTDVHESYQASVAAKVADILQIPAFLCRQTDLIVEVSQTNAIVNIKKGQFMNPKDMQYSVLKALKTRDKSIQSPTYETALKNGVWLCERGSSFGYGNLVVDMRSLKIMREFAPVIFDATHSVQMPSFAPILARAAAAVGIDGLFAETHVDPKNALSDGANMLKPDELEQLVTDMLKIQNLF 4zhx A 2.99 BS01 4O7 A 1 L22 G23 V24 G25 V30 A43 K45 I77 M93 E94 Y95 V96 G99 E100 E143 N144 L146 A156 D157 L14 G15 V16 G17 V22 A35 K37 I69 M85 E86 Y87 V88 G91 E92 E135 N136 L138 A148 D149 2.7.11.1,2.7.11.27,2.7.11.31 P54646 GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQGLPSYLFPEDPSYDANVIDDEAVKEVCEAVAYHLIIDNRRIMNQASEFYLASKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDLGSHTMDFFEMCASLITTL 4zhx B 2.99 BS01 C1V B 1 V81 R83 T106 R107 S108 V113 V4 R6 T29 R30 S31 V36 Q9Y478 RPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKQEPYVCKFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKP 4zhx C 2.99 BS01 4O7 C 1 L22 G23 V24 G25 V30 A43 I77 M93 E94 Y95 V96 E100 E143 N144 L146 A156 D157 L14 G15 V16 G17 V22 A35 I69 M85 E86 Y87 V88 E92 E135 N136 L138 A148 D149 2.7.11.1,2.7.11.27,2.7.11.31 P54646 GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQGLPSYLFPEDPSYDANVIDDEAVKEVCECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSSAMHIPPGLKPHPERMPPLIAAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDLGSHTMDFFEMCASLITTLA 4zhx C 2.99 BS02 C1V C 1 V11 L18 G19 K29 K31 I46 D88 F90 V3 L10 G11 K21 K23 I38 D80 F82 2.7.11.1,2.7.11.27,2.7.11.31 P54646 GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQGLPSYLFPEDPSYDANVIDDEAVKEVCECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSSAMHIPPGLKPHPERMPPLIAAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDLGSHTMDFFEMCASLITTLA 4zhx E 2.99 BS01 C2Z E 1 H151 R152 S226 H298 R299 S314 S316 H125 R126 S200 H272 R273 S288 S290 P54619 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 4zhx E 2.99 BS02 C2Z E 2 T87 T89 H151 S226 S242 K243 F244 T61 T63 H125 S200 S216 K217 F218 P54619 SVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 4zhx F 2.99 BS02 AMP F 2 H151 T200 I204 A205 V225 S226 A227 H298 I312 S314 S316 D317 H126 T175 I179 A180 V200 S201 A202 H273 I287 S289 S291 D292 P54619 NSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 4zj8 A 2.75 BS01 SUV A 1 A102 S103 V106 W112 I122 P123 Q126 V130 Q179 M183 E204 H216 F219 I314 N318 H344 V347 Y348 A77 S78 V81 W87 I97 P98 Q101 V105 Q154 M158 E179 H191 F194 I444 N448 H474 V477 Y478 O43613 DYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQGIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAGDPGELANAILKALELSRSDLSKFRENCKKRAMSFSKQMRARRKTAKMLMVVLLVFALCYLPISVLNILKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAF 4zjc A 2.83 BS01 4OT A 1 S103 W112 I122 P123 Q126 V130 Q179 M183 F219 I314 N318 H344 Y348 S78 W87 I97 P98 Q101 V105 Q154 M158 F194 I444 N448 H474 Y478 O43613 DYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQGIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAGDPGELANAILKALELSRSDLSKFRENCKKRAMSFSKQMRARRKTAKMLMVVLLVFALCYLPISVLNILKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAF 5aal A 2.45 BS01 8L8 A 1 F1 I13 N46 D47 Y48 T51 I52 D54 Q133 N135 Y137 D140 F1 I13 N46 D47 Y48 T51 I52 D54 Q133 N135 Y137 D140 Q6JKW3 FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPT 5ag0 A 1.75 BS01 HEM A 1 E162 F166 L167 D168 G169 I170 A171 L219 Q221 V253 R255 H304 I305 T308 R309 R311 R332 L357 F359 F370 L373 I397 I398 E160 F164 L165 D166 G167 I168 A169 L217 Q219 V251 R253 H302 I303 T306 R307 R309 R330 L355 F357 F368 L371 I395 I396 1.11.1.19 I2DBY1 SLNTDDIQGDILVGMHKQKQLFYFFAINDPATFKTHLASDIAPVVASVTQLSNVATQPLVALNIAFSNTGLLALGVTDNLGDSLFANGQAKDATSFKESTSSWVPQFAGTGIHGVIILASDTTDLIDQQVASIESTFGSSISKLYSLSASIRPGNEAGHEMFGFLDGIAQPAINGFNTPLPGQNIVDAGVIITGATNDPITRPSWAVGGSFLAFRQLEQLVPEFNKYLLDNAPAGSGSLQARADLLGARMVGRWKSGAPIDLTPTADDPALGADAQRNNNFTYSHAGFDLGSDQSHCPFSAHIRKTRPRADLGGSLTPPNLSAGANSIMRSGIPYGPEVTSAESASNTTTQERGLAFVAYQAQLSQGFHFLQQTWADNANFPPGKTPATVGLDPIIGQNNGQPRVVNGLLPSNSSASLSIPQFVVSHGGEYFFSPPISAIGGRLSA 5ag0 A 1.75 BS02 GOA A 1 D168 G169 R332 S333 G334 D166 G167 R330 S331 G332 1.11.1.19 I2DBY1 SLNTDDIQGDILVGMHKQKQLFYFFAINDPATFKTHLASDIAPVVASVTQLSNVATQPLVALNIAFSNTGLLALGVTDNLGDSLFANGQAKDATSFKESTSSWVPQFAGTGIHGVIILASDTTDLIDQQVASIESTFGSSISKLYSLSASIRPGNEAGHEMFGFLDGIAQPAINGFNTPLPGQNIVDAGVIITGATNDPITRPSWAVGGSFLAFRQLEQLVPEFNKYLLDNAPAGSGSLQARADLLGARMVGRWKSGAPIDLTPTADDPALGADAQRNNNFTYSHAGFDLGSDQSHCPFSAHIRKTRPRADLGGSLTPPNLSAGANSIMRSGIPYGPEVTSAESASNTTTQERGLAFVAYQAQLSQGFHFLQQTWADNANFPPGKTPATVGLDPIIGQNNGQPRVVNGLLPSNSSASLSIPQFVVSHGGEYFFSPPISAIGGRLSA 5ags A 1.47 BS01 38Y A 1 F335 T336 T337 R338 T341 Y430 V431 L432 Y435 I440 M441 V443 H446 D447 R449 D450 F16 T17 T18 R19 T22 Y109 V110 L111 Y114 I119 M120 V122 H125 D126 R128 D129 6.1.1.4 P9WFV1 GAVALFSARAVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAASWPAGVNPLWTYGGGTPGEAIAAYRRAIAAKSDLERQEEKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARI 5ajg A 1.11 BS01 LBV A 1 T20 T21 C24 E27 I29 Y176 M186 F203 S206 H207 T208 P209 A212 Y216 R254 T256 S257 M259 H260 Y263 M267 S272 S274 V288 H290 T15 T16 C19 E22 I24 Y156 M166 F183 S186 H187 T188 P189 A192 Y196 R234 T236 S237 M239 H240 Y243 M247 S252 S254 V268 H270 2.7.13.3 Q9RZA4 LPFFPPLYLGGPEITTENCEREPIHIPGSIQPHGALLTADGHSGEVLQVSLNAATFLGQEPTVLRGQTLAALLPEQWPALQAALLQYRATLDWPAAGHLSLTVHRVAELLILEFEPTHALRNAMFALESAPNLRALAEVATQTVRELTGFDRVMLYKFAPDATGEMIAEARREGMQAFLGHRFPASHTPAQARALYTRHLLRLTADTRAAAVPLDPVLNPQTNAPTPLGGAVLRATSPMHMQYLRNMGVGSSLSVSVVVGGQLWGLIVCHHQTPYVLPPDLRTTLEYLGRKLSGQVQRKEA 5ak1 A 2.64 BS01 CA A 1 K763 D766 D768 T771 A868 E869 K728 D731 D733 T736 A833 E834 A3DHG6 ASPQRGRPRLNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGFNAVHLYAECFDPRYPAPGSKAPGYAVNEIDKIVERTRELGLYLVITIGNGANNGNHNAQWARDFWKFYAPRYAKETHVLYEIHNEPVAWGPPYSSSTANPPGAVDMEIDVYRIIRTYAPETPVLLFSYAVFGGKGGAAEALKDIRAFNKAVFGNENAVWTNEAVAFHGYAGWQETTIAVEELLKAGYPCFMTEYAGGAWGSGMGGLDVELTYELERLGVSWLTFQYIPPTGVSDDVTKPEYFSALVENSGLSWTPDYGNWPAARGVYGNGGLARETATWINNFLTGTTRIEAEDFDWGGNGVSYYDTDSVNVGGQYRPDEGVDIEKTSDTGGGYNVGWISEGEWLEYTIRVRNPGYYNLSLRVAGISGSRVQVSFGNQDKTGVWELPATGGFQTWTTATRQVFLGAGLQKLRINALSGGFNLNWIELSPISTGTIPDGTYKFLNRANGKTLQEVTGNNSIITADYKGITEQHWKIQHIGGGQYRISSAGRGWNWNWWMGFGTVGWWGTGSSTCFIISPTGDGYYRIVLVGDGTNLQISSGDPSKIEGKAFHGGANQQWAILPVSAPAFPTGLSAVLDSSGNTANLTWNAAPGANSYNVKRSTKSGGPYTTIATNITSTNYTDTGVATGTKYYYVVSAVSNGVETLNSAEAILQYPKLTGTVIGTQGSWNNIGNTIHKAFDGDLNTFFDGPTANGCWLGLDFGEGVRNVITQIKFCPRSGYEQRMIGGIFQGANKEDFSDAVTLFTITSLPGSGTLTSVDVDNPTGFRYVRYLSPDGSNGNIAELQFFGTPAG 5ak1 A 2.64 BS02 CA A 2 D392 D394 V396 G407 D409 D357 D359 V361 G372 D374 A3DHG6 ASPQRGRPRLNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGFNAVHLYAECFDPRYPAPGSKAPGYAVNEIDKIVERTRELGLYLVITIGNGANNGNHNAQWARDFWKFYAPRYAKETHVLYEIHNEPVAWGPPYSSSTANPPGAVDMEIDVYRIIRTYAPETPVLLFSYAVFGGKGGAAEALKDIRAFNKAVFGNENAVWTNEAVAFHGYAGWQETTIAVEELLKAGYPCFMTEYAGGAWGSGMGGLDVELTYELERLGVSWLTFQYIPPTGVSDDVTKPEYFSALVENSGLSWTPDYGNWPAARGVYGNGGLARETATWINNFLTGTTRIEAEDFDWGGNGVSYYDTDSVNVGGQYRPDEGVDIEKTSDTGGGYNVGWISEGEWLEYTIRVRNPGYYNLSLRVAGISGSRVQVSFGNQDKTGVWELPATGGFQTWTTATRQVFLGAGLQKLRINALSGGFNLNWIELSPISTGTIPDGTYKFLNRANGKTLQEVTGNNSIITADYKGITEQHWKIQHIGGGQYRISSAGRGWNWNWWMGFGTVGWWGTGSSTCFIISPTGDGYYRIVLVGDGTNLQISSGDPSKIEGKAFHGGANQQWAILPVSAPAFPTGLSAVLDSSGNTANLTWNAAPGANSYNVKRSTKSGGPYTTIATNITSTNYTDTGVATGTKYYYVVSAVSNGVETLNSAEAILQYPKLTGTVIGTQGSWNNIGNTIHKAFDGDLNTFFDGPTANGCWLGLDFGEGVRNVITQIKFCPRSGYEQRMIGGIFQGANKEDFSDAVTLFTITSLPGSGTLTSVDVDNPTGFRYVRYLSPDGSNGNIAELQFFGTPAG 5ak1 A 2.64 BS03 CA A 3 D392 D409 W424 E429 D357 D374 W389 E394 A3DHG6 ASPQRGRPRLNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGFNAVHLYAECFDPRYPAPGSKAPGYAVNEIDKIVERTRELGLYLVITIGNGANNGNHNAQWARDFWKFYAPRYAKETHVLYEIHNEPVAWGPPYSSSTANPPGAVDMEIDVYRIIRTYAPETPVLLFSYAVFGGKGGAAEALKDIRAFNKAVFGNENAVWTNEAVAFHGYAGWQETTIAVEELLKAGYPCFMTEYAGGAWGSGMGGLDVELTYELERLGVSWLTFQYIPPTGVSDDVTKPEYFSALVENSGLSWTPDYGNWPAARGVYGNGGLARETATWINNFLTGTTRIEAEDFDWGGNGVSYYDTDSVNVGGQYRPDEGVDIEKTSDTGGGYNVGWISEGEWLEYTIRVRNPGYYNLSLRVAGISGSRVQVSFGNQDKTGVWELPATGGFQTWTTATRQVFLGAGLQKLRINALSGGFNLNWIELSPISTGTIPDGTYKFLNRANGKTLQEVTGNNSIITADYKGITEQHWKIQHIGGGQYRISSAGRGWNWNWWMGFGTVGWWGTGSSTCFIISPTGDGYYRIVLVGDGTNLQISSGDPSKIEGKAFHGGANQQWAILPVSAPAFPTGLSAVLDSSGNTANLTWNAAPGANSYNVKRSTKSGGPYTTIATNITSTNYTDTGVATGTKYYYVVSAVSNGVETLNSAEAILQYPKLTGTVIGTQGSWNNIGNTIHKAFDGDLNTFFDGPTANGCWLGLDFGEGVRNVITQIKFCPRSGYEQRMIGGIFQGANKEDFSDAVTLFTITSLPGSGTLTSVDVDNPTGFRYVRYLSPDGSNGNIAELQFFGTPAG 5ak1 A 2.64 BS04 CA A 4 E377 E379 Y420 N509 E342 E344 Y385 N474 A3DHG6 ASPQRGRPRLNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGFNAVHLYAECFDPRYPAPGSKAPGYAVNEIDKIVERTRELGLYLVITIGNGANNGNHNAQWARDFWKFYAPRYAKETHVLYEIHNEPVAWGPPYSSSTANPPGAVDMEIDVYRIIRTYAPETPVLLFSYAVFGGKGGAAEALKDIRAFNKAVFGNENAVWTNEAVAFHGYAGWQETTIAVEELLKAGYPCFMTEYAGGAWGSGMGGLDVELTYELERLGVSWLTFQYIPPTGVSDDVTKPEYFSALVENSGLSWTPDYGNWPAARGVYGNGGLARETATWINNFLTGTTRIEAEDFDWGGNGVSYYDTDSVNVGGQYRPDEGVDIEKTSDTGGGYNVGWISEGEWLEYTIRVRNPGYYNLSLRVAGISGSRVQVSFGNQDKTGVWELPATGGFQTWTTATRQVFLGAGLQKLRINALSGGFNLNWIELSPISTGTIPDGTYKFLNRANGKTLQEVTGNNSIITADYKGITEQHWKIQHIGGGQYRISSAGRGWNWNWWMGFGTVGWWGTGSSTCFIISPTGDGYYRIVLVGDGTNLQISSGDPSKIEGKAFHGGANQQWAILPVSAPAFPTGLSAVLDSSGNTANLTWNAAPGANSYNVKRSTKSGGPYTTIATNITSTNYTDTGVATGTKYYYVVSAVSNGVETLNSAEAILQYPKLTGTVIGTQGSWNNIGNTIHKAFDGDLNTFFDGPTANGCWLGLDFGEGVRNVITQIKFCPRSGYEQRMIGGIFQGANKEDFSDAVTLFTITSLPGSGTLTSVDVDNPTGFRYVRYLSPDGSNGNIAELQFFGTPAG 5bp2 A 1.75 BS01 MG A 1 T925 E926 D978 T30 E31 D83 I7FI52 PSVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAYCEMALAAVTPVLGDTGEVHDLKFHDMLLLDDATPVWVSAAVTAPGTAEFGVETHQSGDRTQRATAVLRGDVDAERPAAHSIDALLAAHPNRVDGDELRAGFGTVGIGHGAAFAGLSEAYVATAAEPTVVAAVALPGPLRSGQRGYTVHPALLDACFQSVIAHPEVQNIASGMLLPLGVRRLRAYGSTRNVRYCLSRIVKADSFGVEADLELLDADGTVLLSAMGLQLGTGNSD 5bts B 1.77 BS01 III A 1 V2 N3 Q4 H5 L6 C7 L11 A14 L15 V18 C19 R22 G23 F24 F25 Y26 T27 P28 T30 V2 N3 Q4 H5 L6 C7 L11 A14 L15 V18 C19 R22 G23 F24 F25 Y26 T27 P28 T30 P01308 26921119 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5buk A 1.95 BS01 FAD A 1 I10 G11 G13 P14 A15 F33 E34 S35 R40 H42 V43 G44 E45 S46 R122 R145 V146 A177 S178 G179 R181 Q183 A201 G295 D296 G313 D314 F318 P321 S324 G326 V327 I9 G10 G12 P13 A14 F32 E33 S34 R39 H41 V42 G43 E44 S45 R121 R144 V145 A176 S177 G178 R180 Q182 A200 G289 D290 G307 D308 F312 P315 S318 G320 V321 J7H1A1 EPQFDVGIIGGGPAGSTTASYLARAGLKVALFESDNFPREHVGESLVPATTPVLVDIDAFDKVEAAGFPKKFGAAWTSADSGPSDKMGFTGLDHDFRAAEIMFNERTQSGVHKDYTFHVDRGQFDLLLLKHAEEQGAKVHQGVRVNRVNFDGAFPVLETSVAGQRAKVPVKMVVDASGRRTQLGSQLKVKEKDPVFNQYAIHTWFDNFDRKALAVDQSQSDFIFIHFLPVIDTWVWQIPITDTITSVGVVTQKERLDLEKFFWDTLGSRPELHKALKESEQVRPLKTEGDYSYALTKVCGDNFLMVGDAARFVDPIFSSGVSVALNSARIASADIIAAHRAGDYSKKRFDTYESMLRRGVNNWYEFISIYYRLNILFTAFVQDPRYRIDVLKMLQGDVYDDEEPKALAAMREIVKAVEEDPNHLWHPFLGSLKA 5bul A 1.98 BS01 FAD A 1 I12 G13 G15 P16 A17 I35 E36 K37 E38 R42 H44 I45 G46 E47 S48 R101 G122 M123 V124 A156 S157 G158 N160 A182 W213 M271 D291 F295 P298 S301 G303 V304 A307 I7 G8 G10 P11 A12 I30 E31 K32 E33 R37 H39 I40 G41 E42 S43 R96 G117 M118 V119 A151 S152 G153 N155 A177 W208 M265 D285 F289 P292 S295 G297 V298 A301 HYDVVIIGSGPAGSLCGIECRKKGLSVLCIEKEQFPRFHIGESLTGNAGQIIRDLGLAEDMDAAGFPDKPGVNVIGSLSKNEFFIPILAPTWQVRRSDFDDMIKRKAVEHGVEYKLGMVTDVIKDGEKVVGALYKADGVEHQVRSKVLVDASGQNTFLSRKGVAGKRQIEFFSQQIASFAHYKGVERDLPPFSTNTTILYSKQYHWSWIIPISPDTDSLGVVIPKDLYYKECNPDDAIAWGMDHISPELKRRFKNAERQGDSQSMADFSYRIEPFVGDGWMCIGDAHRFLDPIFSSGVSVAMKEGIRAAEAIAQVVAGQDWKAPFYAYRDWSNGGQQIWADLIRYFWIYPIFFGYQMQNPRDEVIRLLGGCCFDGWKAPAIFRNAIEEYDRK 5c7o O 1.73 BS01 NAD O 1 N81 G82 F83 G84 R85 I86 N105 D106 P107 F108 I109 K151 S169 T170 G171 Y173 S193 A194 C224 A255 N388 Y392 N8 G9 F10 G11 R12 I13 N32 D33 P34 F35 I36 K78 S96 T97 G98 Y100 S120 A121 C151 A182 N315 Y319 1.2.1.12 O14556 26921398 RELTVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEFRNGQLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVISAPSPDAPMFVMGVNENDYNPGSMNIVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHSYTATQKTVDGPSRKAWRDGRGAHQNIIPASTGAAKAVTKVIPELKGKLTGMAFRVPTPDVSVVDLTCRLAQPAPYSAIKEAVKAAAKGPMAGILAYTEDEVVSTDFLGDTHSSIFDAKAGIALNDNFVKLISWYDNEYGYSHRVVDLLRYMFSRDK 5ce4 A 0.98 BS01 OLA A 1 F16 Y19 M20 L23 V25 T29 A33 T36 P38 T53 F57 K58 T60 A75 D76 R78 L104 L115 L117 R126 Y128 F16 Y19 M20 L23 V25 T29 A33 T36 P38 T53 F57 K58 T60 A75 D76 R78 L104 L115 L117 R126 Y128 P05413 VDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKE 5ch7 A 2.20 BS05 ZN A 1 H81 D82 H76 D77 G8QM55 SGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5ch7 C 2.20 BS03 MGD C 1 K76 D170 W200 G201 S202 N203 Q206 T207 I228 P230 D231 N233 G248 D250 G421 G422 G423 W427 I458 G459 N761 P763 H764 S765 R766 S768 V769 H770 R830 H835 R882 K68 D162 W192 G193 S194 N195 Q198 T199 I220 P222 D223 N225 G240 D242 G413 G414 G415 W419 I450 G451 N753 P755 H756 S757 R758 S760 V761 H762 R822 H827 R874 G8QM55 FEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5ch7 D 2.20 BS02 SF4 D 1 C137 N138 H139 C140 P143 A144 C145 V163 C180 Y182 K196 C131 N132 H133 C134 P137 A138 C139 V157 C174 Y176 K190 G8QM54 APRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5ch7 D 2.20 BS04 SF4 D 3 Y14 C31 W35 R47 C197 I198 G199 C200 P210 A211 C212 Y8 C25 W29 R41 C191 I192 G193 C194 P204 A205 C206 G8QM54 APRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5ch7 E 2.20 BS03 MGD E 1 K76 D170 W200 G201 N203 Q206 T207 R208 I228 P230 D231 N233 G248 D250 G421 G422 G423 W427 I458 G459 N761 P763 H764 S765 R766 S768 V769 H770 R830 R882 K69 D163 W193 G194 N196 Q199 T200 R201 I221 P223 D224 N226 G241 D243 G414 G415 G416 W420 I451 G452 N754 P756 H757 S758 R759 S761 V762 H763 R823 R875 G8QM55 AFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5ch7 F 2.20 BS02 SF4 F 1 C137 N138 H139 C140 P143 A144 C145 C180 P185 K196 C132 N133 H134 C135 P138 A139 C140 C175 P180 K191 G8QM54 KAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5chc A 2.38 BS05 BSY A 1 N35 V139 F164 Y168 D170 G459 N31 V135 F160 Y164 D166 G455 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5chc C 2.38 BS05 BSY C 1 N35 F164 Y165 Y168 D170 I458 G459 N28 F157 Y158 Y161 D163 I451 G452 G8QM55 AFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5chc D 2.38 BS02 SF4 D 1 C137 N138 H139 C140 C145 V163 C180 Y182 P185 K196 C132 N133 H134 C135 C140 V158 C175 Y177 P180 K191 G8QM54 KAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5chc D 2.38 BS04 SF4 D 3 C31 W35 R47 M136 C197 G199 C200 A211 C212 C26 W30 R42 M131 C192 G194 C195 A206 C207 G8QM54 KAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5chc E 2.38 BS04 MD1 E 1 L33 N35 Y168 D170 H426 Y536 R537 G538 N539 Q543 K545 I564 N565 R567 D569 W584 K587 D615 S762 H764 V769 H770 S771 T772 H835 Q849 C852 Q881 R882 L26 N28 Y161 D163 H419 Y529 R530 G531 N532 Q536 K538 I557 N558 R560 D562 W577 K580 D608 S755 H757 V762 H763 S764 T765 H828 Q842 C845 Q874 R875 G8QM55 AFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5chc E 2.38 BS05 BSY E 1 N35 V139 F164 Y165 Y168 D170 I458 G459 N28 V132 F157 Y158 Y161 D163 I451 G452 G8QM55 AFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQWKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5chc F 2.38 BS02 SF4 F 1 C137 N138 C140 P143 C145 C180 P185 K196 C132 N133 C135 P138 C140 C175 P180 K191 G8QM54 KAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5clo M 2.30 BS01 NS8 M 1 P1 S37 R39 P1 S37 R39 5.3.2.6 Q01468 PIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEYAKGHAGIGGELA 5clo N 2.30 BS01 NS8 M 1 H6 I7 L8 H6 I7 L8 5.3.2.6 Q01468 PIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEYAKGHAGIGGELA 5clo O 2.30 BS01 NS8 M 1 R39 I41 R39 I41 5.3.2.6 Q01468 PIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEYAKGHAGIGGELA 5cob A 2.65 BS01 NAP A 1 G36 T38 G39 I40 A65 R66 R67 C83 D84 V85 S108 W109 I110 M121 Q142 T143 G144 Y178 P201 A202 V204 S211 M212 M213 G13 T15 G16 I17 A42 R43 R44 C60 D61 V62 S85 W86 I87 M98 Q119 T120 G121 Y155 P178 A179 V181 S188 M189 M190 1.3.1.99 K7WDL7 26868105 MAKSYKSVALVVGVTGIVGSSLAEVLKLPDTPGGPWKVYGVARRPCPVWLAKKPVEYIQCDVSDNQETISKLSPLKDITHIFYVSWIGSEDCQTNATMFKNILNSVIPNASNLQHVCLQTGIKHYFGIFEEGSKVVPHDSPFTEDLPRLNVPNFYHDLEDILYEETGKNNLTWSVHRPALVFGFSPCSMMNIVSTLCVYATICKHENKALVYPGSKNSWNCYADAVDADLVAEHEIWAAVDPKAKNQVLNCNNGDVFKWKHIWKKLAEEFGIEMVGYVEGKEQVSLAELMKDKDQVWDEIVKKNNLVPTKLKEIAAFWFADIAFCSENLISSMNKSKELGFLGFRNSMKSFVSCIDKMRDYRFIP 5cob A 2.65 BS02 XOG A 1 G144 I145 K146 F149 Y178 M213 F342 I345 A346 S349 G121 I122 K123 F126 Y155 M190 F319 I322 A323 S326 1.3.1.99 K7WDL7 26868105 MAKSYKSVALVVGVTGIVGSSLAEVLKLPDTPGGPWKVYGVARRPCPVWLAKKPVEYIQCDVSDNQETISKLSPLKDITHIFYVSWIGSEDCQTNATMFKNILNSVIPNASNLQHVCLQTGIKHYFGIFEEGSKVVPHDSPFTEDLPRLNVPNFYHDLEDILYEETGKNNLTWSVHRPALVFGFSPCSMMNIVSTLCVYATICKHENKALVYPGSKNSWNCYADAVDADLVAEHEIWAAVDPKAKNQVLNCNNGDVFKWKHIWKKLAEEFGIEMVGYVEGKEQVSLAELMKDKDQVWDEIVKKNNLVPTKLKEIAAFWFADIAFCSENLISSMNKSKELGFLGFRNSMKSFVSCIDKMRDYRFIP 5csw A 2.66 BS01 P06 A 1 G464 S465 G466 V471 K483 L505 L514 F516 I527 T529 Q530 W531 C532 F583 G593 D594 F595 G16 S17 G18 V23 K35 L57 L66 F68 I79 T81 Q82 W83 C84 F135 G145 D146 F147 2.7.11.1 P15056 26916115 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNNIFLHEDNTVKIGDFGSILWMAPEVIRMQDSNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELAREL 5csw B 2.66 BS01 P06 B 1 S465 V471 K483 L505 L514 F516 I527 T529 Q530 W531 C532 F583 G593 D594 F595 S19 V25 K37 L59 L68 F70 I81 T83 Q84 W85 C86 F137 G147 D148 F149 2.7.11.1 P15056 26916115 SDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNNIFLHEDNTVKIGDFGLSILWMAPEVIRPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELAREL 5csx A 2.51 BS01 54J A 1 I463 V471 A481 K483 L505 L514 F516 I527 T529 W531 C532 G593 D594 F595 L597 K601 I16 V24 A34 K36 L58 L67 F69 I80 T82 W84 C85 G146 D147 F148 L150 K154 2.7.11.1 P15056 26916115 DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNNIFLHEDNTVKIGDFGLATVKSRSGSILWMAPEVIRMQDPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELARE 5csx A 2.51 BS02 GLC A 1 E501 V504 L505 I513 L567 I572 H574 G593 D594 K601 R603 E54 V57 L58 I66 L120 I125 H127 G146 D147 K154 R156 2.7.11.1 P15056 26916115 DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNNIFLHEDNTVKIGDFGLATVKSRSGSILWMAPEVIRMQDPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELARE 5cxv A 2.70 BS01 III C 1 N60 S126 R137 R218 E222 S380 L381 V382 K383 E384 A387 N41 S107 R118 R199 E203 S361 L362 V363 K364 E365 A368 3.2.1.17 P11229 KGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASQASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDK 5cxv A 2.70 BS02 0HK A 1 D105 Y106 S109 W157 T189 T192 A193 A196 F197 W402 Y405 N406 Y428 C431 Y432 D86 Y87 S90 W138 T170 T173 A174 A177 F178 W383 Y386 N387 Y409 C412 Y413 3.2.1.17 P11229 KGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASQASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDK 5cxv A 2.70 BS03 Y01 A 1 F50 K57 Y62 L65 C69 V107 W150 F154 F31 K38 Y43 L46 C50 V88 W131 F135 3.2.1.17 P11229 KGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASQASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDK 5d1o A 2.65 BS01 ATP A 1 F71 K73 I74 R76 E95 E96 K97 M98 N102 R118 E151 F175 V234 K236 K246 F65 K67 I68 R70 E89 E90 K91 M92 N96 R112 E145 F169 V228 K230 K240 O27289 26896806 DIPFDLIQERTGVPSSRLKVAFARGSLRLLESAGMQALLFKKPLGDLEAGTVIYLGDETEVIRGFPKIRRTLLLSPTIQEHFRDRVAVEEKMNGYNVRIACLSSGETVALTRGGHVCPFTTRKAQELLDLSEFFREHPDLVICGEMIGRDNPYVSQDYPEVGPLGFRVFDLREKNTNRPLPVEERRALLDSYGLPNVRLFGVYPIEEAASEVADIIRALGMAGREGVVMKDPSMEVPPLKYTSSQAHARELAYAFSYPFDFGRPFFFSRVIREGFQAYELDESDDETRERARRLGEAIIYPMLERIKSISAGEAAYEDTVIDVEDREAAEEFIRHLVRLGVSATLADYRDGRATIRRFYQSTTDRINNYLKGGLY 5d1o B 2.65 BS01 SO4 B 1 K73 I74 K97 R118 K246 K67 I68 K91 R112 K240 O27289 26896806 DIPFDLIQERTGVPSSRLKVAFARGSLRLLESAGMQALLFKKPLGDLEAGTVIYLGDETEVIRGFPKIRRTLLLSPTIQEHFRDRVAVEEKMNGYNVRIACLSSGETVALTRGGHVCPFTTRKAQELLDLSEFFREHPDLVICGEMIGRDNPYVSQDYPEVGPLGFRVFDLREKNTNRPLPVEERRALLDSYGLPNVRLFGVYPIEEAASEVADIIRALGMAGREGVVMKDPSMEVPPLKYTSSQAHARELAYAFSYPFDFGRPFFFSRVIREGFQAYELDESDDETRERARRLGEAIIYPMLERIKSISAGEAAYEDTVIDVEDREAAEEFIRHLVRLGVSATLADYRDGRATIRRFYQSTTDRINNYLKGGLY 5d1o B 2.65 BS02 SO4 B 2 Q162 D163 R255 Q156 D157 R249 O27289 26896806 DIPFDLIQERTGVPSSRLKVAFARGSLRLLESAGMQALLFKKPLGDLEAGTVIYLGDETEVIRGFPKIRRTLLLSPTIQEHFRDRVAVEEKMNGYNVRIACLSSGETVALTRGGHVCPFTTRKAQELLDLSEFFREHPDLVICGEMIGRDNPYVSQDYPEVGPLGFRVFDLREKNTNRPLPVEERRALLDSYGLPNVRLFGVYPIEEAASEVADIIRALGMAGREGVVMKDPSMEVPPLKYTSSQAHARELAYAFSYPFDFGRPFFFSRVIREGFQAYELDESDDETRERARRLGEAIIYPMLERIKSISAGEAAYEDTVIDVEDREAAEEFIRHLVRLGVSATLADYRDGRATIRRFYQSTTDRINNYLKGGLY 5d1o B 2.65 BS03 MG B 1 K97 M98 E151 E231 K91 M92 E145 E225 O27289 26896806 DIPFDLIQERTGVPSSRLKVAFARGSLRLLESAGMQALLFKKPLGDLEAGTVIYLGDETEVIRGFPKIRRTLLLSPTIQEHFRDRVAVEEKMNGYNVRIACLSSGETVALTRGGHVCPFTTRKAQELLDLSEFFREHPDLVICGEMIGRDNPYVSQDYPEVGPLGFRVFDLREKNTNRPLPVEERRALLDSYGLPNVRLFGVYPIEEAASEVADIIRALGMAGREGVVMKDPSMEVPPLKYTSSQAHARELAYAFSYPFDFGRPFFFSRVIREGFQAYELDESDDETRERARRLGEAIIYPMLERIKSISAGEAAYEDTVIDVEDREAAEEFIRHLVRLGVSATLADYRDGRATIRRFYQSTTDRINNYLKGGLY 5d1p A 2.20 BS01 SO4 A 1 R76 K246 R278 R70 K240 R272 O27289 26896806 DIPFDLIQERTGVPSSRLKVAFARGSLRLLESAGMQALLFKKPLGDLEAGTVIYLGDETEVIRGFPKIRRTLLLSPTIQEHFRDRVAVEEKMNGYNVRIACLSSGETVALTRGGHVCPFTTRKAQELLDLSEFFREHPDLVICGEMIGRDNPYVSQDYPEVGPLGFRVFDLREKNTNRPLPVEERRALLDSYGLPNVRLFGVYPIEEAASEVADIIRALGMAGREGVVMKDPSMEVPPLKYTSSQAHARELAYAFSYPFDFGRPFFFSRVIREGFQAYELDESDDETRERARRLGEAIIYPMLERIKSISAGEAAYEDTVIDVEDREAAEEFIRHLVRLGVSATLADYRDGRATIRRFYQSTTDRINNYLKGGLY 5d2c A 2.06 BS03 IMD A 1 D13 Q14 K59 D12 Q13 K58 P0AE68 26569142 ADKELKFLVVDDQSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWKMPNMDGLELLKTIRADGAMSALPVLMVTAYAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM 5d2c A 2.06 BS04 IMD A 2 K59 A88 Y89 K58 A87 Y88 P0AE68 26569142 ADKELKFLVVDDQSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWKMPNMDGLELLKTIRADGAMSALPVLMVTAYAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM 5d2c B 2.06 BS04 IMD B 2 L46 G49 G50 Y51 L45 G48 G49 Y50 P0AE68 26569142 ADKELKFLVVDDQSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWKMPNMDGLELLKTIRADGAMSALPVLMVTAYAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM 5d4j B 2.00 BS01 CL A 1 D98 H135 D95 H132 1.7.2.1 P38501 ATAAEIAALPRQKVELVDPPFVHAHSQVAEGGPKVVEFTMVIEEKKIVIDDAGTEVHAMAFNGTVPGPLMVVHQDDYLELTLINPETNTLMHNIDFHAATGALGGGGLTEINPGEKTILRFKATKPGVFVYHCAPPGMVPWHVVSGMNGAIMVLPREGLHDGKGKALTYDKIYYVGEQDFYVPRDENGKYKKYEAPGDAYEDTVKVMRTLTPTHVVFNGAVGALTGDKAMTAAVGEKVLIVHSQANRDTRPHLIGGHGDYVWATGKFNTPPDVDQETWFIPGGAAGAAFYTFQQPGIYAYVNHNLIEAFELGAAAHFKVTGEWNDDLMTSVLAPSG 5d6m A 1.65 BS01 HEM A 1 P44 R48 W51 P145 D146 A147 F158 L171 M172 A174 H175 G178 K179 T180 E181 N184 S185 W191 L232 T234 P41 R45 W48 P142 D143 A144 F155 L168 M169 A171 H172 G175 K176 T177 E178 N181 S182 W188 L229 T231 1.11.1.5 P00431 LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYENYIGYGPELVRLAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGYVRTFFQRLNMNDREVVALMGAHALGKTELKNSGYEGPWGAANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL 5d6m A 1.65 BS02 MN A 1 E37 E45 E34 E42 1.11.1.5 P00431 LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYENYIGYGPELVRLAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGYVRTFFQRLNMNDREVVALMGAHALGKTELKNSGYEGPWGAANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL 5dq9 A 1.95 BS01 KD2 A 1 G33 I51 S52 G53 G54 S55 Y56 H95 G100A T100B N100C G33 I51 S52 G54 G55 S56 Y57 H99 G105 T106 N107 EVQLVESGGDLVKPGGSLKLSCAGSGITFSGYGMSWVRQTPDKSLEWVALISNGGSYAYYSDSVKGRFTISRDNAKNTLYLQMSSLRSDDTAIYYCARHKGLRGGTNAMDYWGQGTSVTVSSAKTTPPSVYPLAPGCGDTTGSSVTLGCLVKGYFPESVTVTWNSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSETVTCSVAHPASSTTVDKKLEPS 5dq9 C 1.95 BS01 KD2 C 1 G33 S52 G53 G54 S55 Y56 H95 T100B N100C G33 S52 G54 G55 S56 Y57 H99 T106 N107 EVQLVESGGDLVKPGGSLKLSCAGSGITFSGYGMSWVRQTPDKSLEWVALISNGGSYAYYSDSVKGRFTISRDNAKNTLYLQMSSLRSDDTAIYYCARHKGLRGGTNAMDYWGQGTSVTVSSAKTTPPSVYPLAPGCGDTTGSSVTLGCLVKGYFPESVTVTWNSSVHTFPALLQSGLYTMSSSVTVPSSTWPSETVTCSVAHPASSTTVDKKLEPS 5dq9 H 1.95 BS01 KD2 H 1 G33 S52 G53 G54 S55 Y56 H95 G100A T100B N100C G33 S52 G54 G55 S56 Y57 H99 G105 T106 N107 EVQLVESGGDLVKPGGSLKLSCAGSGITFSGYGMSWVRQTPDKSLEWVALISNGGSYAYYSDSVKGRFTISRDNAKNTLYLQMSSLRSDDTAIYYCARHKGLRGGTNAMDYWGQGTSVTVSSAKTTPPSVYPLAPGCGDTTGSSVTLGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSETVTCSVAHPASSTTVDKKLEPS 5dqd H 1.94 BS01 KD2 H 1 G33 S52 R52A G53 G54 S55 Y56 H95 G100A T100B N100C G33 S52 R53 G54 G55 S56 Y57 H99 G105 T106 N107 EVKLVESGGDLVKPGGSLKLSCAASGFSFSSHGMSWVRQTPDKRLEWVALISRGGSYTYYSDSVKGRFTISRDNAKNTLYLQMSGLRSEDTAIYYCTRHKGLRRGTNAMDYWGQGTSVTVSAAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR 5dqq A 2.87 BS01 CA A 1 L609 N612 N625 L555 N558 N571 Q94KI8 PFQKAAALVDLAEDGIGLPVEILDQSSFSARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPFSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAG 5dqq A 2.87 BS02 CA A 2 D454 E528 D408 E477 Q94KI8 PFQKAAALVDLAEDGIGLPVEILDQSSFSARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPFSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAG 5dqq A 2.87 BS03 CA A 3 D335 D337 N339 E341 I342 D343 Q346 D294 D296 N298 E300 I301 D302 Q305 Q94KI8 PFQKAAALVDLAEDGIGLPVEILDQSSFSARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPFSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAG 5dqq A 2.87 BS04 CA A 4 W92 E124 D170 W61 E93 D139 Q94KI8 PFQKAAALVDLAEDGIGLPVEILDQSSFSARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPFSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAG 5dqq A 2.87 BS05 66R A 1 W232 Y251 W191 Y210 Q94KI8 PFQKAAALVDLAEDGIGLPVEILDQSSFSARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPFSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAG 5dro A 2.01 BS02 ZH2 A 1 H58 E73 H74 T179 F180 A181 G198 S199 T203 H226 K227 D230 H253 H57 E72 H73 T178 F179 A180 G197 S198 T202 H225 K226 D229 H252 3.5.1.- O67648 26912110 GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK 5dro B 2.01 BS02 ZH2 B 1 I18 H19 H58 E73 H74 T179 A181 I186 I189 G198 S199 T203 H226 K227 D230 H253 I17 H18 H57 E72 H73 T178 A180 I185 I188 G197 S198 T202 H225 K226 D229 H252 3.5.1.- O67648 26912110 GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK 5drp A 1.89 BS02 5EP A 1 I18 H58 E73 H74 T179 F180 A181 G198 S199 L200 T203 H226 D230 H253 I17 H57 E72 H73 T178 F179 A180 G197 S198 L199 T202 H225 D229 H252 3.5.1.- O67648 26912110 GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK 5drp B 1.89 BS02 5EP B 1 H19 E73 H74 T179 F180 A181 I189 K190 G195 G198 S199 T203 H226 D230 H18 E72 H73 T178 F179 A180 I188 K189 G194 G197 S198 T202 H225 D229 3.5.1.- O67648 26912110 GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK 5drq A 1.63 BS03 5EM A 1 E77 H78 T190 F191 I197 R201 G209 S210 V211 H237 D241 H264 E77 H78 T190 F191 I197 R201 G209 S210 V211 H237 D241 H264 3.5.1.- P47205 26912110 MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISY 5drr A 1.59 BS03 5EN A 1 L18 M62 E77 H78 T190 F191 I197 G209 S210 V211 V216 H237 K238 D241 H264 L18 M62 E77 H78 T190 F191 I197 G209 S210 V211 V216 H237 K238 D241 H264 3.5.1.- P47205 26912110 MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISY 5e17 C 3.20 BS01 NUC G 1 F394 G1023 K1024 Q1030 R1031 M1035 F388 G1017 K1018 Q1024 R1025 M1029 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEEGLVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 5e17 C 3.20 BS02 NUC H 1 R142 K167 G169 P170 W171 R243 Y256 R266 D326 R331 L418 R422 V427 R136 K161 G163 P164 W165 R237 Y250 R260 D320 R325 L412 R416 V421 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEEGLVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 5e17 C 3.20 BS03 NUC I 1 Q390 Q393 R420 N448 I452 Q567 K838 K846 H999 Q384 Q387 R414 N442 I446 Q561 K832 K840 H993 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEEGLVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 5e17 D 3.20 BS01 NUC G 1 R586 K610 R615 R622 R628 A705 A1089 G1092 Y1093 Q1441 N1442 R584 K608 R613 R620 R626 A703 A1087 G1090 Y1091 Q1425 N1426 2.7.7.6 Q8RQE8 KEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEILAELPEPYLFRAEEEGVVELKELEEGAFLVLRREDEPVATYFLPVGMTPLVVHGEIVEKGQPLAEAKGLLRMPRQVRAAQVEAEEEGETVYLTLFLEWTEPKDYRVQPHMNVVVPEGARVEAGDKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTITQGLPRVIELFEARRPKAKAVISEIDGVVRIEETEEKLSVFVESEGFSKEYKLPKEARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEA 5e17 F 3.20 BS01 NUC H 1 D79 V81 R82 L85 G89 L93 A190 N191 R193 L194 K200 F209 K226 E228 R231 F233 K234 S236 T237 Y238 T240 W241 D2 V4 R5 L8 G12 L16 A113 N114 R116 L117 K123 F132 K149 E151 R154 F156 K157 S159 T160 Y161 T163 W164 Q5SKW1 SDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDPDLIREVVRAKILGSARVRHIPGLKETLDPKTVEEIDQKLKSLPKEHKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAFFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD 5e18 C 3.30 BS01 NUC G 1 R134 F394 G1023 K1024 Q1030 R1031 M1035 R128 F388 G1017 K1018 Q1024 R1025 M1029 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEEGLVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 5e18 C 3.30 BS02 NUC I 1 Q390 R420 P444 N448 I452 Q567 K838 H999 Q384 R414 P438 N442 I446 Q561 K832 H993 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEEGLVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 5e18 C 3.30 BS03 NUC H 1 R142 K167 R168 G169 P170 W171 R266 I325 D326 R350 R353 L418 R422 V427 R136 K161 R162 G163 P164 W165 R260 I319 D320 R344 R347 L412 R416 V421 2.7.7.6 Q8RQE9 MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRETFPIEEGLVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETLARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYVYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRERMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 5e18 D 3.30 BS03 NUC H 1 P109 K494 R1266 P107 K492 R1250 2.7.7.6 Q8RQE8 KEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEILAELPEPYLFRAEEEGVVELKELEEGAFLVLRREDEPVATYFLPVGMTPLVVHGEIVEKGQPLAEAKGLLRMPRQVRAAQVEAEEEGETVYLTLFLEWTEPKDYRVQPHMNVVVPEGARVEAGDKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTITQGLPRVIELFEARRPKAKAVISEIDGVVRIEETEEKLSVFVESEGFSKEYKLPKEARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEA 5e18 F 3.30 BS01 NUC H 1 V81 L85 L93 A190 R193 L194 V196 S197 K200 T203 S208 F209 R231 F233 K234 S236 T237 Y238 T240 W241 V4 L8 L16 A113 R116 L117 V119 S120 K123 T126 S131 F132 R154 F156 K157 S159 T160 Y161 T163 W164 Q5SKW1 SDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDPDLIREVVRAKILGSARVRHIPGLKETLDPKTVEEIDQKLKSLPKEHKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLEGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAFFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD 5e3m A 2.89 BS02 NUC D 1 N73 Q74 T75 R76 R85 R89 N66 Q67 T68 R69 R78 R82 P0A6R3 SDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 5e7o B 2.40 BS04 SF4 B 3 C31 W35 R47 M136 C197 G199 C200 P210 A211 C212 C27 W31 R43 M132 C193 G195 C196 P206 A207 C208 G8QM54 MKAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5e7o C 2.40 BS01 SF4 C 1 H32 V34 C36 G38 C40 G73 C74 G77 H28 V30 C32 G34 C36 G69 C70 G73 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQEKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5e7o C 2.40 BS03 MGD C 1 N35 K76 D170 W200 G201 N203 Q206 T207 R208 I228 S229 P230 D231 N233 G248 D250 G421 G422 G423 W427 I458 G459 N761 P763 H764 S765 R766 S768 H770 R830 H835 R882 N31 K72 D166 W196 G197 N199 Q202 T203 R204 I224 S225 P226 D227 N229 G244 D246 G417 G418 G419 W423 I454 G455 N757 P759 H760 S761 R762 S764 H766 R826 H831 R878 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQEKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5e7o C 2.40 BS04 MD1 C 1 N35 P138 Y168 D170 R537 G538 N539 Q543 K545 I564 N565 I566 R567 D569 S581 W584 K587 D615 S762 H764 V769 H770 S771 T772 H835 C836 Q849 C852 Q881 N31 P134 Y164 D166 R533 G534 N535 Q539 K541 I560 N561 I562 R563 D565 S577 W580 K583 D611 S758 H760 V765 H766 S767 T768 H831 C832 Q845 C848 Q877 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQEKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5e7o D 2.40 BS01 F3S D 1 C149 P150 A153 I154 C170 K171 G172 A173 Q174 A175 C176 A194 C145 P146 A149 I150 C166 K167 G168 A169 Q170 A171 C172 A190 G8QM54 MKAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5e7o D 2.40 BS02 SF4 D 1 C137 N138 H139 C140 P143 A144 C145 C180 Y182 P185 C133 N134 H135 C136 P139 A140 C141 C176 Y178 P181 G8QM54 MKAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5e7o E 2.40 BS04 MD1 E 1 L33 N35 P138 Y168 D170 R537 G538 N539 Q543 K545 I564 N565 I566 R567 D569 S581 W584 K587 D615 S762 H764 V769 H770 S771 T772 H835 C836 Q849 Q881 R882 L29 N31 P134 Y164 D166 R533 G534 N535 Q539 K541 I560 N561 I562 R563 D565 S577 W580 K583 D611 S758 H760 V765 H766 S767 T768 H831 C832 Q845 Q877 R878 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQEKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5e7o F 2.40 BS04 SF4 F 3 C31 W35 R47 M136 C197 I198 G199 C200 P210 C212 C27 W31 R43 M132 C193 I194 G195 C196 P206 C208 G8QM54 MKAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5e7o G 2.40 BS04 MD1 G 1 N35 Y168 D170 Y536 R537 G538 N539 Q543 K545 I564 N565 R567 D569 W584 K587 D615 S762 H764 V769 H770 S771 T772 H835 C836 Q849 C852 Q881 N31 Y164 D166 Y532 R533 G534 N535 Q539 K541 I560 N561 R563 D565 W580 K583 D611 S758 H760 V765 H766 S767 T768 H831 C832 Q845 C848 Q877 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQEKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5e7o H 2.40 BS01 F3S H 1 C149 N151 A153 I154 I165 C170 K171 G172 A173 Q174 A175 C176 A194 C145 N147 A149 I150 I161 C166 K167 G168 A169 Q170 A171 C172 A190 G8QM54 MKAPRRQLTYVTDLNKCIGCQTCTVACKKLWTTGPGQDFMYWRNVETAPGLGYPRNWQTKGGGYKNGELQKGKIPPMIDYGIPFEFDYAGRLFEGKPGRVRPSPTPRSAPNWDEDQGAGEYPNNSFFYLPRMCNHCTKPACLEACPNEAIYKREQDGIVVIHQDKCKGAQACVQSCPYAKPYFNPLTNKANKCIGCFPRIEQGVAPACVAQCVGRAMHVGFVDDVNSSVYKLIKQYKVALPLHPEFGTEPNVFYVPPVLGPRIEMANGEPSTDPKIPLAQLEGLFGKQVRDVLAILQSEREKKMKGLASDLMDVLIGRRSTDMMISPLT 5e7o I 2.40 BS03 MGD I 1 N35 C36 K76 D170 G201 S202 N203 T207 R208 I228 S229 P230 D231 N233 G248 D250 G421 G422 G423 W427 I458 G459 N761 P763 H764 S765 S768 H770 R830 H835 R882 N31 C32 K72 D166 G197 S198 N199 T203 R204 I224 S225 P226 D227 N229 G244 D246 G417 G418 G419 W423 I454 G455 N757 P759 H760 S761 S764 H766 R826 H831 R878 G8QM55 ISGAFEYSGWENFHRTQWSWDKKTRGAHLVNCTGACPHFVYSKDGVVMREEQSKDIAPMPNIPEYNPRGCNKGECGHDYMYGPHRIKYPLIRVGERGEGKWRRATWEEALDMIADKCVDTIKNHAPDCISVYSPVPAVSPVSFSAGHRFAHYIGAHAHTFYDWYGDHPTGQTQTCGVQGDTCETADWFNSKYIILWGSNPTQTRIPDAHFLSEAQLNGAKIVSISPDYNSSTIKVDKWIHPQPGTDGALAMAMAHVIIKEKLYDAHSLKEQTDLSYLVRSDTKRFLREADVVAGGSKDKFYFWNAKTGKPVIPKGSWGDQPEKKGSPVGFLGRNTFAFPKGYIDLGDLDPALEGKFNMQLLDGKTVEVRPVFEILKSRLMADNTPEKAAKITGVTAKAITELAREFATAKPSMIICGGGTQHWYYSDVLLRAMHLLTALTGTEGTNGGGMNHYIGQEKPAFVAGLVALAFPEGVNKQRFCQTTIWTYIHAEVNDEIISSDIDTEKYLRDSITTGQMPNMPEQGRDPKVFFVYRGNWLNQAKGQKYVLENLWPKLELIVDINIRMDSTALYSDVVLPSAHWYEKLDLNVTSEHSYINMTEPAIKPMWESKTDWQIFLALAKRVEMAAKRKKYEKFNDEKFKWVRDLSNLWNQMTMDGKLAEDEAAAQYILDNAPQSKGITIQMLREKPQRFKSNWTSPLKEGVPYTPFQYFVVDKKPWPTLTGRQQFYLDHDTFFDMGVELPTYKAPIDADKYPFRFNSPHSRHSVHSTFKDNVLMLRLQRGGPSIEMSPLDAKPLGIKDNDWVEAWNNHGKVICRVKIRNGEQRGRVSMWHCPELYMDLLTGGSQSVCPVRINPTNLVGNYGHLFFRPNYYGPAGSQRDVRVNVKRYIGATPISF 5ec9 A 2.30 BS02 5LO A 1 I268 A271 A272 Q275 W305 L309 I310 F313 R316 I324 L326 A327 V342 I345 F346 V349 C432 H435 L436 F439 I22 A25 A26 Q29 W59 L63 I64 F67 R70 I78 L80 A81 V96 I99 F100 V103 C186 H189 L190 F193 P19793 26820900 DMPVERILEAELAVEPDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 5edb A 1.18 BS01 5M8 A 1 F17 M21 T30 A34 A37 S56 F58 A76 D77 R127 F19 M23 T32 A36 A39 S58 F60 A78 D79 R129 P15090 26878596 SHMCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA 5edc A 1.29 BS01 5M7 A 1 F16 M20 T29 A33 A36 S53 S55 F57 A75 D76 I104 V115 C117 F18 M22 T31 A35 A38 S55 S57 F59 A77 D78 I106 V117 C119 P15090 26878596 AMCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA 5ede A 2.20 BS02 5M6 A 1 L675 S677 V678 I692 F696 I711 M713 M714 Q726 F729 L219 S221 V222 I236 F240 I255 M257 M258 Q270 F273 3.1.4.17,3.1.4.35 Q9Y233 26878596 QGLMQFTLPVRLCREIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5ede B 2.20 BS02 5M6 B 1 Y524 S573 L635 L675 S677 V678 I692 F696 M713 M714 Q726 F729 Y68 S117 L179 L219 S221 V222 I236 F240 M257 M258 Q270 F273 3.1.4.17,3.1.4.35 Q9Y233 26878596 AGLMQFTLPVRLCREIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEEA 5ede C 2.20 BS02 5M6 C 1 Y524 S573 L635 L675 S677 V678 I692 M713 Q726 F729 Y67 S116 L178 L218 S220 V221 I235 M256 Q269 F272 3.1.4.17,3.1.4.35 Q9Y233 26878596 GLMQFTLPVRLCREIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5edg A 2.30 BS02 5MG A 1 H525 F639 L675 S677 V678 I692 M713 Q726 F729 H68 F182 L218 S220 V221 I235 M256 Q269 F272 3.1.4.17,3.1.4.35 Q9Y233 26878596 GLMQFTLPVRLCREIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5edg B 2.30 BS02 5MG B 1 H525 L635 L675 S677 V678 I692 F696 M713 Q726 F729 H69 L179 L219 S221 V222 I236 F240 M257 Q270 F273 3.1.4.17,3.1.4.35 Q9Y233 26878596 QGLMQFTLPVRLCREIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEEA 5edg C 2.30 BS02 5MG C 1 Y524 H525 L635 L675 S677 V678 I692 F696 M713 Q726 F729 V733 Y67 H68 L178 L218 S220 V221 I235 F239 M256 Q269 F272 V276 3.1.4.17,3.1.4.35 Q9Y233 26878596 GLMQFTLPVRLCREIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5edg D 2.30 BS02 5MG D 1 H525 L635 L675 S677 I692 F696 M713 Q726 F729 V733 H70 L180 L220 S222 I237 F241 M258 Q271 F274 V278 3.1.4.17,3.1.4.35 Q9Y233 26878596 AQGLMQFTLPVRLCREIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRG 5edh A 2.03 BS02 5MF A 1 L675 V678 I692 Y693 F696 P712 M713 K718 E721 V722 G725 Q726 F729 L217 V220 I234 Y235 F238 P254 M255 K260 E263 V264 G267 Q268 F271 3.1.4.17,3.1.4.35 Q9Y233 26878596 LMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5edi B 2.20 BS02 5M9 B 1 L675 S677 V678 I692 Y693 F696 P712 M713 K718 E721 G725 Q726 F729 L224 S226 V227 I241 Y242 F245 P261 M262 K267 E270 G274 Q275 F278 3.1.4.17,3.1.4.35 Q9Y233 26878596 TSEEWQGLMQFTLPVRLCREIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEEA 5ege A 2.00 BS01 FUL A 1 W339 G348 W349 R351 W316 G325 W326 R328 3.1.4.-,3.1.4.38 Q8BGN3 26888014 RKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTVPTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSDHGMTDIFWMDKVIELSNYISLDDLQQVKDRGPVVSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLTLVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPDFKSNFRAAPIRSVDVYNIMAHVAGITPLPNNGSWSRVVSMLK 5ege A 2.00 BS02 ZN A 1 D193 H197 H354 D170 H174 H331 3.1.4.-,3.1.4.38 Q8BGN3 26888014 RKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTVPTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSDHGMTDIFWMDKVIELSNYISLDDLQQVKDRGPVVSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLTLVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPDFKSNFRAAPIRSVDVYNIMAHVAGITPLPNNGSWSRVVSMLK 5ege A 2.00 BS03 ZN A 2 D32 S71 D240 H241 D9 S48 D217 H218 3.1.4.-,3.1.4.38 Q8BGN3 26888014 RKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTVPTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSDHGMTDIFWMDKVIELSNYISLDDLQQVKDRGPVVSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLTLVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPDFKSNFRAAPIRSVDVYNIMAHVAGITPLPNNGSWSRVVSMLK 5egh A 1.80 BS01 FUL A 1 N341 G348 W349 R351 N318 G325 W326 R328 3.1.4.-,3.1.4.38 Q8BGN3 26888014 RKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTVPTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSDHGMTDIFWMDKVIELSNYISLDDLQQVKDRGPVVSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLTLVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPDFKSNFRAAPIRSVDVYNIMAHVAGITPLPNNGSWSRVVSMLK 5egh A 1.80 BS04 PC A 1 D32 S71 Y72 Y75 N92 Y157 Y188 E190 D193 H197 H241 H354 D9 S48 Y49 Y52 N69 Y134 Y165 E167 D170 H174 H218 H331 3.1.4.-,3.1.4.38 Q8BGN3 26888014 RKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTVPTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSDHGMTDIFWMDKVIELSNYISLDDLQQVKDRGPVVSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLTLVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPDFKSNFRAAPIRSVDVYNIMAHVAGITPLPNNGSWSRVVSMLK 5ehv A 1.21 BS01 5ON A 1 H94 H96 H119 L197 T198 T199 P201 H92 H94 H117 L195 T196 T197 P199 4.2.1.1 P00918 26882437 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ehw A 1.39 BS01 5OO A 1 H94 H96 V121 F130 L197 T198 T199 P200 P201 H92 H94 V119 F128 L195 T196 T197 P198 P199 4.2.1.1 P00918 26882437 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5eiy A 2.95 BS01 43Y A 1 A54 K57 G708 L709 L710 A42 K45 G696 L697 L698 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5eiy A 2.95 BS04 BGC A 3 Y433 I438 E439 A443 V551 Y421 I426 E427 A431 V539 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5eiy A 2.95 BS05 BGC A 4 I438 E439 F441 V551 V554 V555 I426 E427 F429 V539 V542 V543 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5eiy A 2.95 BS06 BGC A 5 A429 P430 F441 M452 V554 V555 W558 A417 P418 F429 M440 V542 V543 W546 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5eiy A 2.95 BS12 BGC A 11 F301 W383 M387 S413 W417 F289 W371 M375 S401 W405 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5eiy A 2.95 BS14 C2E A 1 R579 R580 A581 R584 D609 S611 S613 G614 V615 R616 R658 G670 V671 I672 R567 R568 A569 R572 D597 S599 S601 G602 V603 R604 R646 G658 V659 I660 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5eiy A 2.95 BS15 C2E A 2 Q578 R579 R580 R584 R616 R658 Q566 R567 R568 R572 R604 R646 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5eiy A 2.95 BS16 660 A 1 P147 S148 Y149 E151 D180 A225 K226 N229 D246 A247 H249 C318 G319 S320 D343 Q379 R382 W383 F503 V505 T506 K508 P135 S136 Y137 E139 D168 A213 K214 N217 D234 A235 H237 C306 G307 S308 D331 Q367 R370 W371 F491 V493 T494 K496 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5ejw A 2.60 BS01 5PZ A 1 F11 W32 W35 T41 F23 W44 W47 T53 Q8VDS3 HHSSGLVPRGSHMELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASG 5ejz A 2.94 BS02 BGC A 2 Y433 G437 I438 E439 V551 Y421 G425 I426 E427 V539 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5ejz A 2.94 BS03 BGC A 3 Y433 I438 F441 A443 V555 Y421 I426 F429 A431 V543 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5ejz A 2.94 BS04 BGC A 4 A429 P430 M452 V554 V555 W558 A417 P418 M440 V542 V543 W546 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5ejz A 2.94 BS07 BGC A 7 S111 F115 R423 S459 E477 S99 F103 R411 S447 E465 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5ejz A 2.94 BS08 BGC A 8 I114 N118 M300 E480 I102 N106 M288 E468 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5ejz A 2.94 BS12 SHG A 1 K226 D246 C318 T341 E342 D343 K214 D234 C306 T329 E330 D331 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5ejz A 2.94 BS14 C2E A 2 Q578 R579 R580 R584 R616 S659 Q566 R567 R568 R572 R604 S647 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5ejz A 2.94 BS15 UDP A 1 P147 S148 Y149 E151 A225 K226 N229 D246 A247 Q379 R382 F503 V505 T506 K508 P135 S136 Y137 E139 A213 K214 N217 D234 A235 Q367 R370 F491 V493 T494 K496 2.4.1.12 Q3J125 VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLNSMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFMDEPARRRR 5ejz B 2.94 BS02 BGC A 12 M385 P387 R390 S568 M332 P334 R337 S503 Q3J126 PWIIPLRPLAETAQVGPLFRLQGQQARAAFRLFLPTEAVGGTLTLAQRSSIDILPESSQIIVRMNDQEIGRFTPRQFGALGAVTMPLGEAVRAGDNLVTIEAQHRHRIYCGADAEFDLWTEVDLSQSGVALPAAAIGTEPTSFIAALTAQAESGRPVEIRTPTPPDEATLRTLAQALGRPLPDEALPLALSKPWSAETGPTYARITLLPSDADRVSIRRGGDGAVVLVLEHPPEGSPNASLVADLLGATPTLPPPTLPQIPPGRVVTLADMGVDTILTDNRYFNRDIDFQLPDDWLLLASQKAQIGIDYGFAGGLPEGALLLVKVNGTTVRMLPLDRDAAPVKPRLDIRFPARLLHPGPNRLSFESVIPGNPPDQPCPASAGDLMQVLSSTDLEVPPSPRMQMADMARDLAQVTPASVHPATPDGLARTLPFMAAFREVPDAAPVDLTVAGLHDIATVPLNEEGLTPRLLALTLLPSTGPPANALAPLGAAPGEGVMPPLVESNWSDRAQTFVQATLQPVIQTVRRMLRPGDGNLAEWLATRKGTAMLLAPEPGKLWVILGPEAEPARVAEALAMAPRSPGGPRGQVAVLGSDGRWSSWSKPGLLPELREPVSLDNVRSVVGNVASARPPLLLGGMLGLAWISAAIAVGFVLRTR 5eu1 A 1.60 BS01 5SW A 1 H42 F44 F45 F47 V49 I53 A54 Y99 N100 Y106 H21 F23 F24 F26 V28 I32 A33 Y78 N79 Y85 Q9H8M2 26914985 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMS 5eu1 B 1.60 BS01 5SW B 1 H42 F44 F45 F47 V49 I53 N100 Y106 H22 F24 F25 F27 V29 I33 N80 Y86 Q9H8M2 26914985 ESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSM 5eul A 3.70 BS01 BEF A 1 T102 G103 T89 G90 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS02 ADP A 1 M79 F80 F82 Q85 G103 G105 K106 T107 L108 D492 R528 Q529 M66 F67 F69 Q72 G90 G92 K93 T94 L95 D473 R509 Q510 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS03 TBR A 1 D591 Q595 Q598 Y599 L740 D572 Q576 Q579 Y580 L669 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS04 TBR A 2 E798 M801 E802 E719 M722 E723 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS05 TBR A 3 T251 D253 T256 V298 A299 M300 Q301 V304 E544 R547 R548 T234 D236 T239 V281 A282 M283 Q284 V287 E525 R528 R529 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS06 TBR A 4 K302 D303 E440 E443 K447 K462 K285 D286 E423 E426 K430 K445 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS07 TBR A 5 H43 E47 E50 H30 E34 E37 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS08 TBR A 6 N117 T120 H202 E365 K366 N104 T107 H189 E348 K349 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS09 TBR A 7 E625 E628 N629 M689 I693 E601 E604 N605 M624 I628 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS10 TBR A 8 K723 D726 H809 S813 K652 D655 H730 S734 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS11 TBR A 9 E772 D773 E778 E780 E696 D697 E702 E704 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS12 TBR A 10 K229 K232 Y234 A285 H288 H289 G332 E348 K216 K219 Y221 A268 H271 H272 G315 E331 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS13 TBR A 11 E309 D310 K325 K462 H464 E465 E292 D293 K308 K445 H447 E448 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS14 TBR A 12 E443 S446 K450 H456 V458 E426 S429 K433 H439 V441 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS15 TBR A 13 E34 E71 R74 R75 E21 E58 R61 R62 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS16 TBR A 14 T376 E377 E379 K583 E586 G587 F590 T359 E360 E362 K564 E567 G568 F571 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul A 3.70 BS17 TBR A 15 R14 E378 E379 Q388 R1 E361 E362 Q371 P28366 RTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAVTIATNMAGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDEIVENMIKSSLERAIAAYMLELIMDRIITKYNEKEQMREFEKVIVLRAVDSKWMDHIDAMDQLRQGIHLRGSKKTAIAIAVALAGFATVASYAQYEDGCSGELERQHTFAGGPGAPLREYQMEGFAMFEHMIESIEDEVAKFVMKA 5eul Y 3.70 BS01 TBR A 1 E103 R106 E91 R94 A4IJK8 DIRNKIIFTLLMLIVFRIGTFIPVPSVNTDVLKLQDQLNAFGVLNIFCGGALQNFSIFAMGVMPYITASIIVQLLQMDVVPKFAEWSKQGEMGRRKLAQFTRYFTIVLGFIQALGMSYGFNNLAGGMLIQNPIGTYLLIAVVLTAGTAFLMWLGEQITAKGVGNGISIIIFAGIVSGIPTILNQIYAIVRLLLVALAVVAVIVGVIYIQQAFRKIPIQSTHLPLKVNPVIFAVSFLIAPPTIASFFGTNDRRTFDYTHPVGMTIYVVLIIAFTYFYAFVQVNPEQMADNLKKQGGYIPGIRPGKNTQEYVTRILYRLTLVGSLFLAFIAVLPVFFVNFANLPPSAQIGGTSLLIVVGVALETMKQLESQLVKRHYRGFIK 5eul Y 3.70 BS02 TBR A 16 H261 P263 H221 P223 A4IJK8 DIRNKIIFTLLMLIVFRIGTFIPVPSVNTDVLKLQDQLNAFGVLNIFCGGALQNFSIFAMGVMPYITASIIVQLLQMDVVPKFAEWSKQGEMGRRKLAQFTRYFTIVLGFIQALGMSYGFNNLAGGMLIQNPIGTYLLIAVVLTAGTAFLMWLGEQITAKGVGNGISIIIFAGIVSGIPTILNQIYAIVRLLLVALAVVAVIVGVIYIQQAFRKIPIQSTHLPLKVNPVIFAVSFLIAPPTIASFFGTNDRRTFDYTHPVGMTIYVVLIIAFTYFYAFVQVNPEQMADNLKKQGGYIPGIRPGKNTQEYVTRILYRLTLVGSLFLAFIAVLPVFFVNFANLPPSAQIGGTSLLIVVGVALETMKQLESQLVKRHYRGFIK 5eul Y 3.70 BS03 TBR A 17 S289 G292 R301 R302 F304 D305 S244 G247 R251 R252 F254 D255 A4IJK8 DIRNKIIFTLLMLIVFRIGTFIPVPSVNTDVLKLQDQLNAFGVLNIFCGGALQNFSIFAMGVMPYITASIIVQLLQMDVVPKFAEWSKQGEMGRRKLAQFTRYFTIVLGFIQALGMSYGFNNLAGGMLIQNPIGTYLLIAVVLTAGTAFLMWLGEQITAKGVGNGISIIIFAGIVSGIPTILNQIYAIVRLLLVALAVVAVIVGVIYIQQAFRKIPIQSTHLPLKVNPVIFAVSFLIAPPTIASFFGTNDRRTFDYTHPVGMTIYVVLIIAFTYFYAFVQVNPEQMADNLKKQGGYIPGIRPGKNTQEYVTRILYRLTLVGSLFLAFIAVLPVFFVNFANLPPSAQIGGTSLLIVVGVALETMKQLESQLVKRHYRGFIK 5eul Y 3.70 BS04 TBR A 18 M104 R107 M92 R95 A4IJK8 DIRNKIIFTLLMLIVFRIGTFIPVPSVNTDVLKLQDQLNAFGVLNIFCGGALQNFSIFAMGVMPYITASIIVQLLQMDVVPKFAEWSKQGEMGRRKLAQFTRYFTIVLGFIQALGMSYGFNNLAGGMLIQNPIGTYLLIAVVLTAGTAFLMWLGEQITAKGVGNGISIIIFAGIVSGIPTILNQIYAIVRLLLVALAVVAVIVGVIYIQQAFRKIPIQSTHLPLKVNPVIFAVSFLIAPPTIASFFGTNDRRTFDYTHPVGMTIYVVLIIAFTYFYAFVQVNPEQMADNLKKQGGYIPGIRPGKNTQEYVTRILYRLTLVGSLFLAFIAVLPVFFVNFANLPPSAQIGGTSLLIVVGVALETMKQLESQLVKRHYRGFIK 5eul Y 3.70 BS05 TBR Y 1 K240 P242 P348 K214 P216 P298 A4IJK8 DIRNKIIFTLLMLIVFRIGTFIPVPSVNTDVLKLQDQLNAFGVLNIFCGGALQNFSIFAMGVMPYITASIIVQLLQMDVVPKFAEWSKQGEMGRRKLAQFTRYFTIVLGFIQALGMSYGFNNLAGGMLIQNPIGTYLLIAVVLTAGTAFLMWLGEQITAKGVGNGISIIIFAGIVSGIPTILNQIYAIVRLLLVALAVVAVIVGVIYIQQAFRKIPIQSTHLPLKVNPVIFAVSFLIAPPTIASFFGTNDRRTFDYTHPVGMTIYVVLIIAFTYFYAFVQVNPEQMADNLKKQGGYIPGIRPGKNTQEYVTRILYRLTLVGSLFLAFIAVLPVFFVNFANLPPSAQIGGTSLLIVVGVALETMKQLESQLVKRHYRGFIK 5eul Y 3.70 BS06 TBR Y 2 P93 K94 E97 P81 K82 E85 A4IJK8 DIRNKIIFTLLMLIVFRIGTFIPVPSVNTDVLKLQDQLNAFGVLNIFCGGALQNFSIFAMGVMPYITASIIVQLLQMDVVPKFAEWSKQGEMGRRKLAQFTRYFTIVLGFIQALGMSYGFNNLAGGMLIQNPIGTYLLIAVVLTAGTAFLMWLGEQITAKGVGNGISIIIFAGIVSGIPTILNQIYAIVRLLLVALAVVAVIVGVIYIQQAFRKIPIQSTHLPLKVNPVIFAVSFLIAPPTIASFFGTNDRRTFDYTHPVGMTIYVVLIIAFTYFYAFVQVNPEQMADNLKKQGGYIPGIRPGKNTQEYVTRILYRLTLVGSLFLAFIAVLPVFFVNFANLPPSAQIGGTSLLIVVGVALETMKQLESQLVKRHYRGFIK 5ex0 A 2.70 BS01 III D 1 S101 V178 C180 N181 S182 F183 T184 E192 S202 Y239 D241 M244 Q252 Q256 Y257 E294 K329 S102 V179 C181 N182 S183 F184 T185 E193 S203 Y240 D242 M245 Q253 Q257 Y258 E295 K330 2.1.1.43 Q9H7B4 FMEPLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDRKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS 5ex0 A 2.70 BS05 SAH A 1 R14 G15 N16 Y124 N132 C180 N181 S202 L203 L204 N205 H206 Y239 Y257 F259 R15 G16 N17 Y125 N133 C181 N182 S203 L204 L205 N206 H207 Y240 Y258 F260 2.1.1.43 Q9H7B4 FMEPLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDRKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS 5ex3 A 2.41 BS01 III D 1 S101 C180 N181 S182 F183 T184 C186 M190 E192 S202 F216 Y239 L240 D241 M242 Y257 H366 V368 S101 C180 N181 S182 F183 T184 C186 M190 E192 S202 F216 Y239 L240 D241 M242 Y257 H366 V368 2.1.1.43 Q9H7B4 MEPLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDRKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS 5ex3 A 2.41 BS05 SAH A 1 R14 N16 Y124 N132 S202 L203 N205 H206 Y239 Y257 F259 R14 N16 Y124 N132 S202 L203 N205 H206 Y239 Y257 F259 2.1.1.43 Q9H7B4 MEPLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDRKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS 5ezv A 2.99 BS01 STU A 1 L22 G23 V24 G25 V30 A43 K45 I77 M93 E94 Y95 V96 G99 E100 E143 N144 L146 A156 L15 G16 V17 G18 V23 A36 K38 I70 M86 E87 Y88 V89 G92 E93 E136 N137 L139 A149 2.7.11.1,2.7.11.27,2.7.11.31 P54646 DGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASRPHPERVPFKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDLGSHTMDFFEMCASLITTLA 5ezv B 2.99 BS01 C1V A 1 V81 R83 T106 S108 V113 V4 R6 T29 S31 V36 Q9Y478 RPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 5ezv E 2.99 BS02 C2Z E 2 R70 T87 T89 H151 S226 S242 K243 F244 R299 R47 T64 T66 H127 S202 S218 K219 F220 R275 P54619 SNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTG 5ezv F 2.99 BS02 C2Z F 2 R70 T87 T89 H151 S226 S242 K243 F244 H298 R46 T63 T65 H127 S202 S218 K219 F220 H274 P54619 NNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 5f1h A 1.82 BS01 5U6 A 1 H42 G43 F44 F45 F47 V49 I53 A54 N100 Y106 H21 G22 F23 F24 F26 V28 I32 A33 N79 Y85 Q9H8M2 26914985 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMS 5f1h B 1.82 BS01 5U6 B 1 H42 G43 F44 F45 F47 P48 V49 I53 N100 Y106 H22 G23 F24 F25 F27 P28 V29 I33 N80 Y86 Q9H8M2 26914985 ESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSM 5f25 A 1.68 BS01 5TU A 1 F44 F45 V49 I53 A54 Y99 N100 Y106 F23 F24 V28 I32 A33 Y78 N79 Y85 Q9H8M2 26914985 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMS 5f2p B 1.80 BS01 5TY B 1 F44 F45 V49 I53 N100 Y106 F23 F24 V28 I32 N79 Y85 Q9H8M2 26914985 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMS 5f2t A 2.06 BS01 MG A 1 D255 S257 D208 S210 2.3.1.- A0QWG5 GGPEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADL 5f34 A 3.28 BS01 HD6 A 1 L122 L124 W130 A133 G134 F144 T146 V147 R164 F182 C196 M198 S206 P220 G222 E229 L73 L75 W81 A84 G85 F95 T97 V98 R115 F133 C147 M149 S157 P171 G173 E180 2.3.1.- A0QWG5 PEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADLSDERRARL 5f34 B 3.28 BS01 HD6 B 1 W130 A133 G134 F144 T146 V147 A148 E149 R164 C196 M198 P220 G222 W81 A84 G85 F95 T97 V98 A99 E100 R115 C147 M149 P171 G173 2.3.1.- A0QWG5 PEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADLSDERRARL 5f34 C 3.28 BS01 HD6 C 1 L124 W130 A133 G134 L137 F144 R164 C196 M198 D202 P220 G222 L75 W81 A84 G85 L88 F95 R115 C147 M149 D153 P171 G173 2.3.1.- A0QWG5 PEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADLSDERRAR 5f34 D 3.28 BS01 HD6 D 1 V104 W130 A133 G134 F144 T146 V147 E149 R164 F169 F182 C196 M198 R201 D202 P220 G222 V237 V55 W81 A84 G85 F95 T97 V98 E100 R115 F120 F133 C147 M149 R152 D153 P171 G173 V188 2.3.1.- A0QWG5 PEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADLSDERRARL 5f4b A 2.50 BS01 FMN A 1 L91 T94 G95 W98 H134 H135 L79 T82 G83 W86 H118 H119 1.6.5.2 Q2YQ23 26858101 MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELIDQEVPIATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTAGAELALISTQWQMQHHGMIIVPLSYAYREQMGNDVVRGGAPYGRQPSAQELDGARFQGRRVAEITAKLHG 5f4b A 2.50 BS02 FMN B 1 Y12 R79 Y80 Y12 R67 Y68 1.6.5.2 Q2YQ23 26858101 MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELIDQEVPIATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTAGAELALISTQWQMQHHGMIIVPLSYAYREQMGNDVVRGGAPYGRQPSAQELDGARFQGRRVAEITAKLHG 5f4b B 2.50 BS02 FMN B 1 L91 D92 T94 G95 W98 H134 H135 L79 D80 T82 G83 W86 H117 H118 1.6.5.2 Q2YQ23 26858101 MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELIDQEVPIATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTGAELALISTQWQMQHHGMIIVPLSYAYREQMGNDVVRGGAPYGRQPSAQELDGARFQGRRVAEITAKLHG 5fue A 2.20 BS02 UV4 A 1 K20 H141 H142 G150 D186 H188 F216 D285 P291 H292 G339 Y341 K19 H140 H141 G149 D176 H178 F206 D268 P274 H275 G310 Y312 A5H660 SVGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWDSPSRMYEAVTAFHSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYDCPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASGFCYLNDIVLAIHRLVSSQTRVLYVDLDLHHGDGVEEAFWYSPRVVTFSVHHASPGFFPGTGTWNPIFLNGAGRGRFSAFNLPLEEGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNFYPSLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLWTRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFPDSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLY 5fug A 2.70 BS01 III C 1 K74 R91 K57 R74 P0C0S5 SRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAG 5fug A 2.70 BS02 III C 2 R80 T82 P83 R84 Q87 I90 R91 D97 I100 K101 I104 R63 T65 P66 R67 Q70 I73 R74 D80 I83 K84 I87 P0C0S5 SRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAG 5fug A 2.70 BS03 III C 3 R19 S20 P28 V29 G30 R31 H33 R34 K37 G47 A48 T49 R2 S3 P11 V12 G13 R14 H16 R17 K20 G30 A31 T32 P0C0S5 SRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAG 5fug B 2.70 BS01 III C 4 S38 I39 Y42 I54 S55 S56 K57 M59 I61 S64 F65 D68 S4 I5 Y8 I20 S21 S22 K23 M25 I27 S30 F31 D34 P06899 ESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5fug B 2.70 BS02 III C 5 Y40 K43 T90 Y121 Y6 K9 T56 Y87 P06899 ESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5fuu D 4.20 BS01 FUC D 1 W614 Y638 E641 W103 Y127 E130 Q6BC19 AVGIGAVFLGFLGAAGSTMGAASMTLTVQARLLLSGIVQQQNNLLRAIEAQQRMLQLTVWGIKQLQARVLAVERYLGDQQLLGIWGCSGKLICTTAVPWNASWSNKSLDRIWNNMTWMEWEREIDNYTSEIYTLIEESQNQQEKNEQ 5fuu F 4.20 BS01 FUC F 1 Y638 E641 Y127 E130 Q6BC19 AVGIGAVFLGFLGAAGSTMGAASMTLTVQARLLLSGIVQQQNNLLRAIEAQQRMLQLTVWGIKQLQARVLAVERYLGDQQLLGIWGCSGKLICTTAVPWNASWSNKSLDRIWNNMTWMEWEREIDNYTSEIYTLIEESQNQQEKNEQELLELD 5fuu H 4.20 BS01 GAL F 1 H56 V57 V58 H57 V58 V59 RVQLVESGGGVVQPGKSVRLSCVVSDFPFSKYPMYWVRQAPGKGLEWVAAISGDAWHVVYSNSVQGRFLVSRDNVKNTLYLEMNSLKIEDTAVYRCARMFQESGPPRLDRWSGRNYYYYSGMDVWGQGTTVTVSS 5fuu M 4.20 BS01 GAL B 1 H56 V58 H56 V58 VQLVESGGGVVQPGKSVRLSCVVSDFPFSKYPMYWVRQAPGKGLEWVAAISGDAWHVVYSNSVQGRFLVSRDNVKNTLYLEMNSLKIEDTAVYRCARMFQESGPPRLDRWSGRNYYYYSGMDVWGQGTTVTVSSA 5fuu N 4.20 BS01 GAL B 2 F55 S56 F59 S60 IVMTQTPLSLSVTPGQPASISCKSSESLRQSNGKTSLYWYRQKPGQSPQLLVFEVSNRFSGVSDRFVGSGSGTDFTLRISRVEAEDVGFYYCMQSKDFPLTFGGGTKVDLKR 5fv9 A 2.07 BS01 UDP A 1 T143 H145 D176 R201 L204 D224 H226 V330 H359 R362 T69 H71 D102 R127 L130 D150 H152 V256 H285 R288 Q10471 KVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNL 5fv9 B 2.07 BS01 Y6W B 1 T143 H145 D176 R201 L204 S207 D224 H226 V330 E334 R362 T69 H71 D102 R127 L130 S133 D150 H152 V256 E260 R288 Q10471 KVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNL 5fv9 B 2.07 BS03 UDP B 1 T143 F144 H145 D176 R201 L204 D224 H226 V330 H359 R362 T69 F70 H71 D102 R127 L130 D150 H152 V256 H285 R288 Q10471 KVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNL 5fv9 D 2.07 BS01 UDP D 1 T143 F144 H145 D176 R201 G203 L204 D224 H226 V330 E334 H359 R362 T69 F70 H71 D102 R127 G129 L130 D150 H152 V256 E260 H285 R288 Q10471 KVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQILSVEV 5fv9 E 2.07 BS03 Y6W E 1 T143 F144 H145 D176 R201 H226 V330 E334 R362 T69 F70 H71 D102 R127 H152 V256 E260 R288 Q10471 KVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNL 5fv9 F 2.07 BS03 Y6W F 1 T143 F144 H145 D176 R201 D224 H226 V330 E334 R362 T69 F70 H71 D102 R127 D150 H152 V256 E260 R288 Q10471 KVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNL 5ha9 B 4.01 BS01 TP0 B 1 E102 D109 H201 G202 S203 I211 Y235 S243 Y246 E103 D110 H202 G203 S204 I212 Y236 S244 Y247 2.4.2.30 P09874 MKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5hcv A 2.50 BS01 60R A 1 L769 N770 Q776 M807 S810 S811 L814 R817 F829 M845 M852 L938 F941 C942 T945 V954 F956 L28 N29 Q35 M66 S69 S70 L73 R76 F88 M104 M111 L192 F195 C196 T199 V208 F210 P08235 26897089 PVMVLENIEPEIVYAGYPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH 5hcv B 2.50 BS01 60R B 1 L769 N770 L772 Q776 M807 S810 S811 L814 R817 F829 M845 L938 F941 C942 T945 F956 L28 N29 L31 Q35 M66 S69 S70 L73 R76 F88 M104 L188 F191 C192 T195 F206 P08235 26897089 PVMVLENIEPEIVYAGYPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH 5hdt A 2.71 BS01 III E 1 Q47 F88 A92 P93 W137 V138 K139 N142 I143 F145 E146 E187 G188 D189 Q28 F69 A73 P74 W118 V119 K120 N123 I124 F126 E127 E168 G169 D170 Q9NTI5 MEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPHTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYALQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPFLEMIKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQCLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQPTKNYLPPEM 5hdt A 2.71 BS02 IHP A 1 R724 K727 K830 R834 K888 K925 K928 R932 R699 K702 K805 R809 K863 K900 K903 R907 Q9NTI5 MEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPHTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYALQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPFLEMIKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQCLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQPTKNYLPPEM 5hdt B 2.71 BS01 IHP B 1 K727 K830 R834 K888 K925 K928 R932 K687 K790 R794 K848 K885 K888 R892 Q9NTI5 MEISDKISKEEMVRRLKMVVKTFMDMSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIAPHTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYALQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKPFLEMIKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQCLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQTKNYLPPEMKSFF 5hh7 A 1.90 BS01 III P 1 D163 P164 E165 I166 E167 M180 I181 E182 L187 G188 G189 V202 P203 G205 W207 R239 R288 R306 A319 S320 N321 G323 D324 V326 D30 P31 E32 I33 E34 M47 I48 E49 L54 G55 G56 V69 P70 G72 W74 R87 R136 R154 A167 S168 N169 G171 D172 V174 Q9SU24 26876097 KRVYYNKVEFDETEFEIGDDVYVKRREDEDPEIEDCQICFKSDTNIMIECDDCLGGFHLKCLKPPLKEVPEGDWICQFCEVKARTMREKLLSGDLWAARIDKLWKEVDDGVYWIRARWYMIPEETVSGRQPHNLKRELYLTNDFADIEMECILRHCSVKCPKEFSKASNDGDDVFLCEYEYDVHWRSFKRLA 5hh7 A 1.90 BS02 ZN A 1 C169 C172 H191 C194 C36 C39 H58 C61 Q9SU24 26876097 KRVYYNKVEFDETEFEIGDDVYVKRREDEDPEIEDCQICFKSDTNIMIECDDCLGGFHLKCLKPPLKEVPEGDWICQFCEVKARTMREKLLSGDLWAARIDKLWKEVDDGVYWIRARWYMIPEETVSGRQPHNLKRELYLTNDFADIEMECILRHCSVKCPKEFSKASNDGDDVFLCEYEYDVHWRSFKRLA 5hh7 A 1.90 BS03 ZN A 2 C183 C186 C209 C212 C50 C53 C76 C79 Q9SU24 26876097 KRVYYNKVEFDETEFEIGDDVYVKRREDEDPEIEDCQICFKSDTNIMIECDDCLGGFHLKCLKPPLKEVPEGDWICQFCEVKARTMREKLLSGDLWAARIDKLWKEVDDGVYWIRARWYMIPEETVSGRQPHNLKRELYLTNDFADIEMECILRHCSVKCPKEFSKASNDGDDVFLCEYEYDVHWRSFKRLA 5hj0 A 2.64 BS01 ZN A 1 C25 C28 C79 C82 C7 C10 C61 C64 Q9P802 26921242 QPSVFQCKKCFQIVGDSNAWVISHREYLSFTLSDAVENSVRVEDTFKRSDDGLCVYSELSCTRCNEVIGKVYNSTPIYLDDIRDMYTFSMDKLQAYQLGN 5hk7 A 2.95 BS01 VVA A 1 M194 S226 M47 S79 Q0ABW0 26919429 PGIAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQSAHWEAEDAKRIEQEQRAHDERLEMLQLIRDLSSKVDRLERRSG 5hk7 A 2.95 BS02 VVA B 1 F161 E178 G184 M187 Y188 F14 E31 G37 M40 Y41 Q0ABW0 26919429 PGIAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQSAHWEAEDAKRIEQEQRAHDERLEMLQLIRDLSSKVDRLERRSG 5hk7 B 2.95 BS01 VVA B 1 I208 W215 V219 I61 W68 V72 Q0ABW0 26919429 PGIAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQSAHWEAEDAKRIEQEQRAHDERLEMLQLIRDLSSKVDRLERRS 5hk7 B 2.95 BS02 VVA B 2 E178 G184 M187 Y188 F191 E31 G37 M40 Y41 F44 Q0ABW0 26919429 PGIAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQSAHWEAEDAKRIEQEQRAHDERLEMLQLIRDLSSKVDRLERRS 5hk7 C 2.95 BS01 VVA B 3 P212 W215 P65 W68 Q0ABW0 26919429 PGIAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQSAHWEAEDAKRIEQEQRAHDERLEMLQLIRDLSSKVDRLERRS 5hk7 D 2.95 BS01 VVA A 2 F161 G184 F191 M194 F14 G37 F44 M47 Q0ABW0 26919429 PGIAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQSAHWEAEDAKRIEQEQRAHDERLEMLQLIRDLSSKVDRLERRS 5hk7 D 2.95 BS02 VVA C 1 I208 W215 I61 W68 Q0ABW0 26919429 PGIAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQSAHWEAEDAKRIEQEQRAHDERLEMLQLIRDLSSKVDRLERRS 5hkd B 3.80 BS01 CA B 1 L196 E197 L47 E48 Q0ABW0 26919429 IAWIALLLLVIFYVFAVMGTKLFAQSFPEWFGTLGASMYTLFQVMTLESWSMGIARPVIEAYPWAWIYFVSFILVSSFTVLNLFIGIIIESMQEQRAHDERLEMLQLIRDLSSKVD 5hkh A 2.55 BS01 III B 1 K3 V20 L21 S22 P24 T27 P28 A31 V32 F35 K6 V23 L24 S25 P27 T30 P31 A34 V35 F38 P61960 GAMESKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVG 5hkh C 2.55 BS01 III B 1 R15 P17 Y18 K19 R14 P16 Y17 K18 P61960 SKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRD 5hsa A 2.35 BS01 FAS A 1 G13 G15 S16 S17 E38 A39 M59 A87 N88 V89 G92 G93 N97 F98 M99 M100 T225 K226 V227 C268 G269 S272 W566 H567 D605 L606 N616 T617 Y618 G12 G14 S15 S16 E37 A38 M58 A86 N87 V88 G91 G92 N96 F97 M98 M99 T224 K225 V226 C267 G268 S271 W565 H566 D604 L605 N615 T616 Y617 1.1.3.13 F2QY27 26905908 AIPEEFDILVLGGGSSGSCIAGRLANLDHSLKVGLIEAGENNLNNPWVYLPGIYPRNMKLDSKTASFYTSNPSPHLNGRRAIVPCANVLGGGSSINFMMYTRGSASDYDDFQAEGWKTKDLLPLMKKTETYQRACNNPDIHGFEGPIKVSFGNYTYPVCQDFLRASESQGIPYVDDLEDLVTAHGAEHWLKWINRDTGRRSDSAHAFVHSTMRNHDNLYLICNTKVDKIIVEDGRAAAVRTVPSKPLNPKKPSHKIYRARKQIVLSCGTISSPLVLQRSGFGDPIKLRAAGVKPLVNLPGVGRNFQDHYCFFSPYRIKPQYESFDDFVRGDAEIQKRVFDQWYANGTGPLATNGIEAGVKIRPTPEELSQMDESFQEGYREYFEDKPDKPVMHYSIIAGFFGDHTKIPPGKYMTMFHFLEYPFSRGSIHITSPDPYAAPDFDPGFMNDERDMAPMVWAYKKSRETARRMDHFAGEVTSHHPLFPYSSEARALEMDLETSNAYGGPLNLSAGLAHGSWTQPLKKPTAKNEGHVTSNQVELHPDIEYDEEDDKAIENYIREHTETTWHCLGTCSIGPREGSKIVKWGGVLDHRSNVYGVKGLKVGDLSVCPDNVGCNTYTTALLIGEKTATLVGEDLGYSGEALDMTVPQFKLGTYEKTGLARF 5hsa E 2.35 BS01 FAS E 1 G13 G15 S16 S17 E38 A39 M59 A87 V89 G92 G93 I96 N97 F98 M99 M100 T225 K226 V227 S267 C268 G269 S272 W566 H567 D605 L606 N616 T617 Y618 G12 G14 S15 S16 E37 A38 M58 A86 V88 G91 G92 I95 N96 F97 M98 M99 T224 K225 V226 S266 C267 G268 S271 W565 H566 D604 L605 N615 T616 Y617 1.1.3.13 F2QY27 26905908 AIPEEFDILVLGGGSSGSCIAGRLANLDHSLKVGLIEAGENNLNNPWVYLPGIYPRNMKLDSKTASFYTSNPSPHLNGRRAIVPCANVLGGGSSINFMMYTRGSASDYDDFQAEGWKTKDLLPLMKKTETYQRACNNPDIHGFEGPIKVSFGNYTYPVCQDFLRASESQGIPYVDDLEDLVTAHGAEHWLKWINRDTGRRSDSAHAFVHSTMRNHDNLYLICNTKVDKIIVEDGRAAAVRTVPSKPLNPKKPSHKIYRARKQIVLSCGTISSPLVLQRSGFGDPIKLRAAGVKPLVNLPGVGRNFQDHYCFFSPYRIKPQYESFDDFVRGDAEIQKRVFDQWYANGTGPLATNGIEAGVKIRPTPEELSQMDESFQEGYREYFEDKPDKPVMHYSIIAGFFGDHTKIPPGKYMTMFHFLEYPFSRGSIHITSPDPYAAPDFDPGFMNDERDMAPMVWAYKKSRETARRMDHFAGEVTSHHPLFPYSSEARALEMDLETSNAYGGPLNLSAGLAHGSWTQPLKKPTAKNEGHVTSNQVELHPDIEYDEEDDKAIENYIREHTETTWHCLGTCSIGPREGSKIVKWGGVLDHRSNVYGVKGLKVGDLSVCPDNVGCNTYTTALLIGEKTATLVGEDLGYSGEALDMTVPQFKLGTYEKTGLARF 5hsa E 2.35 BS02 CA E 1 E382 K581 E381 K580 1.1.3.13 F2QY27 26905908 AIPEEFDILVLGGGSSGSCIAGRLANLDHSLKVGLIEAGENNLNNPWVYLPGIYPRNMKLDSKTASFYTSNPSPHLNGRRAIVPCANVLGGGSSINFMMYTRGSASDYDDFQAEGWKTKDLLPLMKKTETYQRACNNPDIHGFEGPIKVSFGNYTYPVCQDFLRASESQGIPYVDDLEDLVTAHGAEHWLKWINRDTGRRSDSAHAFVHSTMRNHDNLYLICNTKVDKIIVEDGRAAAVRTVPSKPLNPKKPSHKIYRARKQIVLSCGTISSPLVLQRSGFGDPIKLRAAGVKPLVNLPGVGRNFQDHYCFFSPYRIKPQYESFDDFVRGDAEIQKRVFDQWYANGTGPLATNGIEAGVKIRPTPEELSQMDESFQEGYREYFEDKPDKPVMHYSIIAGFFGDHTKIPPGKYMTMFHFLEYPFSRGSIHITSPDPYAAPDFDPGFMNDERDMAPMVWAYKKSRETARRMDHFAGEVTSHHPLFPYSSEARALEMDLETSNAYGGPLNLSAGLAHGSWTQPLKKPTAKNEGHVTSNQVELHPDIEYDEEDDKAIENYIREHTETTWHCLGTCSIGPREGSKIVKWGGVLDHRSNVYGVKGLKVGDLSVCPDNVGCNTYTTALLIGEKTATLVGEDLGYSGEALDMTVPQFKLGTYEKTGLARF 5huw C 1.95 BS01 III A 1 S105 W142 N146 A148 S149 G150 T151 T155 Q181 W184 N188 G191 D192 N228 W231 N235 R238 N239 W273 Y277 S31 W68 N72 A74 S75 G76 T77 T81 Q107 W110 N114 G117 D118 N154 W157 N161 R164 N165 W199 Y203 P52293 NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 5huw C 1.95 BS02 III B 1 D280 G281 N283 R315 V321 T322 G323 T328 W357 S360 N361 A364 E396 W399 S406 G407 D206 G207 N209 R241 V247 T248 G249 T254 W283 S286 N287 A290 E322 W325 S332 G333 P52293 NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 5hv8 A BS01 66S A 1 I2094 D2095 S2096 L2097 F2120 I49 D50 S51 L52 F75 Q6MZA5 GSHMRLNGLSPQQQQQTLATLVAAATATVLGHHTPESISPATAFKDLGIDSLTALELRNTLTHNTGLDLPPTLIFDHPTPHALTQHLHTRLTQSH 5i0n A 2.28 BS01 ATP A 1 I130 Q132 S137 F139 V150 K152 P209 Q261 L262 F263 V264 I345 D346 I31 Q33 S36 F38 V49 K51 P267 Q306 L307 F308 V309 I380 D381 2.7.1.67,3.2.1.17,2.7.1.67 Q9BTU6 ERNEFPEDPEFEAVVRQAELAIERCIFPERIYQSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKGTGNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKNLGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETA 5i0n A 2.28 BS02 ATP A 2 W359 R360 P363 F364 A367 W368 V444 Q445 W394 R395 P398 F399 A402 W403 V479 Q480 2.7.1.67,3.2.1.17,2.7.1.67 Q9BTU6 ERNEFPEDPEFEAVVRQAELAIERCIFPERIYQSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKGTGNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKNLGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETA 5i0n A 2.28 BS03 CA A 1 N313 D346 N358 D381 2.7.1.67,3.2.1.17,2.7.1.67 Q9BTU6 ERNEFPEDPEFEAVVRQAELAIERCIFPERIYQSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKGTGNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKNLGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETA 5i2b A 1.70 BS01 ZN A 1 C99 H141 H145 C97 H139 H143 3.5.1.88 B1FPK4 HMIREILKMGDPRLLEVAKPVAQFDTPELHEIVADMFETMHHANGAGLAAPQIGIGLQIIIFGFNRYPDAPPVPETVLINPKLEYMPPDMEEGWEGCLSVPGMRGVVSRYAKVRYSGYDQFGAKIDRVAEGFHARVVQHEYDHLIGKLYPMRITDFTRFGFTEVLFP 5i2b A 1.70 BS02 BB2 A 1 N43 G44 A45 G46 Q51 Y69 W96 E97 G98 C99 L100 R106 F134 R137 V138 H141 E142 H145 N44 G45 A46 G47 Q52 Y67 W94 E95 G96 C97 L98 R104 F132 R135 V136 H139 E140 H143 3.5.1.88 B1FPK4 HMIREILKMGDPRLLEVAKPVAQFDTPELHEIVADMFETMHHANGAGLAAPQIGIGLQIIIFGFNRYPDAPPVPETVLINPKLEYMPPDMEEGWEGCLSVPGMRGVVSRYAKVRYSGYDQFGAKIDRVAEGFHARVVQHEYDHLIGKLYPMRITDFTRFGFTEVLFP 5i2r A 2.50 BS02 67A A 1 H525 F639 L675 V678 I692 Y693 F696 M713 Q726 F729 H68 F182 L218 V221 I235 Y236 F239 M256 Q269 F272 3.1.4.17,3.1.4.35 Q9Y233 26878596 GLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5i2r C 2.50 BS02 67A C 1 H525 L635 L675 S677 V678 I692 M713 Q726 F729 H68 L178 L218 S220 V221 I235 M256 Q269 F272 3.1.4.17,3.1.4.35 Q9Y233 26878596 GLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5i2r D 2.50 BS02 67A D 1 Y524 H525 L635 L675 S677 I692 F696 M713 Q726 F729 Y69 H70 L180 L220 S222 I237 F241 M258 Q271 F274 3.1.4.17,3.1.4.35 Q9Y233 26878596 AQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRG 5i3o A 2.40 BS01 IDV A 1 L57 A58 G60 V65 A77 M130 Y132 C133 R134 A135 G136 Q137 N140 E184 N185 L187 C197 D198 L16 A17 G19 V24 A36 M89 Y91 C92 R93 A94 G95 Q96 N99 E143 N144 L146 C156 D157 2.7.11.1 Q9NSY1 RVFAVGRHQVTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMTA 5i3o B 2.40 BS01 IDV B 1 L57 A58 E59 V65 M130 E131 Y132 C133 R134 G136 Q137 N185 L187 C197 D198 L16 A17 E18 V24 M89 E90 Y91 C92 R93 G95 Q96 N144 L146 C156 D157 2.7.11.1 Q9NSY1 RVFAVGRHQVTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMTA 5i3r A 2.40 BS01 IDK A 1 L57 A58 G60 S63 V65 A77 M130 E131 Y132 C133 R134 G136 Q137 E184 N185 L187 C197 D198 L16 A17 G19 S22 V24 A36 M89 E90 Y91 C92 R93 G95 Q96 E143 N144 L146 C156 D157 2.7.11.1 Q9NSY1 RVFAVGRHQVTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMTA 5i70 B 3.00 BS01 III D 1 M15 D34 G36 S76 Y77 G78 S79 I114 I123 Y192 D214 G216 T217 S218 L290 M11 D30 G32 S72 Y73 G74 S75 I110 I119 Y186 D208 G210 T211 S212 L284 W7FF86 SIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCSTKHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADDLEPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDVGYLTIGGIESDFYEGPLTYEKLNHDLYWQIDLDIHFGKYVMQKANAVVDSGTSTITAPTSFLNKFFRDMNVIKVPFLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYILPVDIDDNTFILGDPFMRKYFTVFDYEKESVGFAVAKN 5i72 A 2.90 BS01 ZN A 1 C31 C34 C50 C53 C7 C10 C26 C29 O73557 26912609 HLGPQFCKSCWFENKGLVECNNHYLCLNCLTLLLSVSNRCPICKMPLPTKL 5i72 A 2.90 BS02 ZN A 2 C44 H47 C64 C67 C20 H23 C40 C43 O73557 26912609 HLGPQFCKSCWFENKGLVECNNHYLCLNCLTLLLSVSNRCPICKMPLPTKL 5i8s A 1.89 BS01 NI A 1 H88 H90 E94 H133 H88 H90 E94 H133 1.13.11.54 Q99JT9 26858196 MVQAWYMDESTADPRKPHRAQPDRPVSLEQLRTLGVLYWKLDADKYENDPELEKIRKMRNYSWMDIITICKDTLPNYEEKIKMFFEEHLHLDEEIRYILEGSGYFDVRDKEDKWIRISMEKGDMITLPAGIYHRFTLDEKNYVKAMRLFVGEPVWTPYNRPADHFDARVQYMSFLEGTA 5i8s A 1.89 BS02 LEA A 1 I69 F84 R96 F105 F135 V143 A145 I69 F84 R96 F105 F135 V143 A145 1.13.11.54 Q99JT9 26858196 MVQAWYMDESTADPRKPHRAQPDRPVSLEQLRTLGVLYWKLDADKYENDPELEKIRKMRNYSWMDIITICKDTLPNYEEKIKMFFEEHLHLDEEIRYILEGSGYFDVRDKEDKWIRISMEKGDMITLPAGIYHRFTLDEKNYVKAMRLFVGEPVWTPYNRPADHFDARVQYMSFLEGTA 5i8t A 1.75 BS02 LAC A 1 F84 H88 H90 E94 R96 H133 F135 F84 H88 H90 E94 R96 H133 F135 1.13.11.54 Q99JT9 26858196 MVQAWYMDESTADPRKPHRAQPDRPVSLEQLRTLGVLYWKLDADKYENDPELEKIRKMRNYSWMDIITICKDTLPNYEEKIKMFFEEHLHLDEEIRYILEGSGYFDVRDKEDKWIRISMEKGDMITLPAGIYHRFTLDEKNYVKAMRLFVGEPVWTPYNRPADHFDARVQYMSFLEGTA 5i8y A 1.94 BS02 KMT A 1 I69 F84 R96 I98 F105 F135 V143 A145 I69 F84 R96 I98 F105 F135 V143 A145 1.13.11.54 Q99JT9 26858196 MVQAWYMDESTADPRKPHRAQPDRPVSLEQLRTLGVLYWKLDADKYENDPELEKIRKMRNYSWMDIITICKDTLPNYEEKIKMFFEEHLHLDEEIRYILEGSGYFDVRDKEDKWIRISMEKGDMITLPAGIYHRFTLDEKNYVKAMRLFVGEPVWTPYNRPADHFDARVQYMSFLEGTA 5i93 A 2.24 BS02 69O A 1 I69 F84 R96 F105 F135 A145 I69 F84 R96 F105 F135 A145 1.13.11.54 Q99JT9 26858196 MVQAWYMDESTADPRKPHRAQPDRPVSLEQLRTLGVLYWKLDADKYENDPELEKIRKMRNYSWMDIITICKDTLPNYEEKIKMFFEEHLHLDEEIRYILEGSGYFDVRDKEDKWIRISMEKGDMITLPAGIYHRFTLDEKNYVKAMRLFVGEPVWTPYNRPADHFDARVQYMSFLEGTA 5iai A 1.60 BS01 RB0 A 1 D47 D99 I100 Q208 W259 W277 G315 W316 R389 D15 D67 I68 Q176 W227 W245 G283 W284 R357 B9JM84 KPLDGVTLTLASQNDPFGAVLTKLAAEFKQDTGADLKVEVMDYGTLLTKTTADFVGKTKGYDLVTMDIVWAGAYQANGYSVDLTDWVKRDAAELDLDDIYPVILQSLGQYKGHYVAFPFAAYANVLAYRKDLFQAAGLPVPTTVEELVSDAKKLTDPSKKQYGFVANGQKGPAVAQDWMQYNNQMGGSILDNDGKPALNSPENVKSLTVYKQLFVETAPPGAIEYDWGGREESFRQGAAAMMQTWSVGAPGYSDPASSNVVGKVGITTAPVGKGVPPQYGVGGWGMAINADIDPKQKEAAWTFIKWLVSKKIHKEFNMDGAGSFMRKSQMTDPDLTAKFDFLPVVAKTYENGNGEYRPRIPEYPEIQDILGSAVNSVLAGAAEPQAALDEAQVEAKKLF 5idt A 2.35 BS01 THM A 1 L9 G11 G12 Q83 P86 D87 G88 L89 L109 D111 E197 L8 G10 G11 Q82 P85 D86 G87 L88 L108 D110 E196 2.7.7.24 A4JIV2 TQRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGMRDVLVISTPQDTPRFQQLLGDGSQWGMNLQYAVQPSPDGLAQAFIIGEQFIGNAPSALVLGDNIYYGHDFQPLLKAADAQSSGATVFAYHVHDPERYGVVQFNAQGQAVSIEEKPKAPKSNYAVTGLYFYDQQVVDIAKAVKPSARGELEITSVNQAYMQQGQLNVQTMGRGYAWLDTGTHDSLLDASQFIATLENRQGLKVACPEEIAWRSGWINASQLEALVQPLTKNGYGQYLMQILK 5idt D 2.35 BS01 THM D 1 L9 A10 G11 Q27 Q83 P86 D87 G88 L89 L109 G110 D111 L8 A9 G10 Q26 Q82 P85 D86 G87 L88 L108 G109 D110 2.7.7.24 A4JIV2 TQRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGMRDVLVISTPQDTPRFQQLLGDGSQWGMNLQYAVQPSPDGLAQAFIIGEQFIGNAPSALVLGDNIYYGHDFQPLLKAADAQSSGATVFAYHVHDPERYGVVQFNAQGQAVSIEEKPKAPKSNYAVTGLYFYDQQVVDIAKAVKPSARGELEITSVNQAYMQQGQLNVQTMGRGYAWLDTGTHDSLLDASQFIATLENRQGLKVACPEEIAWRSGWINASQLEALVQPLTKNGYGQYLMQILK 5idu A 1.95 BS01 FAD A 1 F135 L137 S138 G143 S144 W168 S170 H217 L219 A368 Y372 A375 E377 V378 F130 L132 S133 G138 S139 W163 S165 H212 L214 A363 Y367 A370 E372 V373 B2JPK4 IDPHGALAWPFFEARHRELAAGIEAWATQHLACVQHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGHGDTIDTRAVCLLRETLANHDGLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVFARTGEAPGARGISAFIVDADTPGLQIAERIDVIAPHPLARLHFDSARVPRSQMLGAPGEGFKIAMRTLDVFRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVYRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALRIYEGATEVQQLIVGRDLLKAHAAQRQQ 5idu A 1.95 BS02 FAD B 1 R278 M280 L285 F288 Q346 L347 G349 G350 V353 R273 M275 L280 F283 Q341 L342 G344 G345 V348 B2JPK4 IDPHGALAWPFFEARHRELAAGIEAWATQHLACVQHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGHGDTIDTRAVCLLRETLANHDGLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVFARTGEAPGARGISAFIVDADTPGLQIAERIDVIAPHPLARLHFDSARVPRSQMLGAPGEGFKIAMRTLDVFRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVYRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALRIYEGATEVQQLIVGRDLLKAHAAQRQQ 5idu C 1.95 BS01 FAD C 1 F135 L137 S138 G143 S144 W168 S170 H217 A368 Y372 A375 E377 F143 L145 S146 G151 S152 W176 S178 H225 A376 Y380 A383 E385 B2JPK4 AHHHHHHMLAANLIDPHGALAWPFFEARHRELAAGIEAWATQHLACVQHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGHGDTIDTRAVCLLRETLANHDGLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVFARTGEAPGARGISAFIVDADTPGLQIAERIDVIAPHPLARLHFDSARVPRSQMLGAPGEGFKIAMRTLDVFRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVYRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALRIYEGATEVQQLIVGRDLLKAHAAQRQQ 5idu D 1.95 BS01 FAD C 1 R278 M280 L285 Q346 L347 G349 G350 V353 R273 M275 L280 Q341 L342 G344 G345 V348 B2JPK4 IDPHGALAWPFFEARHRELAAGIEAWATQHLACVQHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGHGDTIDTRAVCLLRETLANHDGLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVFARTGEAPGARGISAFIVDADTPGLQIAERIDVIAPHPLARLHFDSARVPRSQMLGAPGEGFKIAMRTLDVFRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVYRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALRIYEGATEVQQLIVGRDLLKAHAAQRQQ 5if9 A 1.80 BS01 ANP A 1 G20 G21 V22 A23 K24 T25 T26 P135 L192 P221 R222 T223 S235 G12 G13 V14 A15 K16 T17 T18 P127 L184 P213 R214 T215 S216 A0QTQ5 VTRVLAVANQKGGVAKTTTVASIGAALTEQGRRVLLVDLDPQGCLTFSLGHDPDKLPVSVHEVLLGDVEPSAALVRTDEGMTLLPANIDLAGAEAMLLMRAGREYALKRALAKLDGDFDVVIIDCPPSLGVLTLNGLTAAHDVIVPLQCETLAHRGVGQFLRTISDVQQITNPDLKLLGALPTLYDSRTTHSRDVLLDVADRYELPVLAPPIPRTSVLAGRKSKGAIAYREFADALLRHWKSGRKMPTFTP 5ify A 2.25 BS01 TRH A 1 L8 G10 G11 Q82 P85 D86 G87 L88 D110 Y145 G146 E161 K162 V172 T173 Y176 R194 E196 T200 W223 L7 G9 G10 Q81 P84 D85 G86 L87 D109 Y144 G145 E160 K161 V171 T172 Y175 R193 E195 T199 W222 2.7.7.24 A4JC15 ARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDTPRFESMLGDGSQWGMNIQYATQPSPDGLAQAFVIGRDFVGNEPSALILGDNIFYGHDLAKQLERASAKDTGATVFAYHVQDPERYGVVEFDREFRAISIEEKPAKPRSSYAVTGLYFYDRQVCDIAADIKPSARGELEITDVNSRYLAAGQLDVELMGRGYAWLDTGTHDSLIEAGTFIATLQKRQGLMVACPEEIAYRRNWIDAEQVLKLAQPLAKNAYGQYLRNLLTHQVAW 5ify A 2.25 BS02 UMP A 1 Y114 G115 H116 D117 A251 E255 I256 W294 Y113 G114 H115 D116 A250 E254 I255 W293 2.7.7.24 A4JC15 ARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDTPRFESMLGDGSQWGMNIQYATQPSPDGLAQAFVIGRDFVGNEPSALILGDNIFYGHDLAKQLERASAKDTGATVFAYHVQDPERYGVVEFDREFRAISIEEKPAKPRSSYAVTGLYFYDRQVCDIAADIKPSARGELEITDVNSRYLAAGQLDVELMGRGYAWLDTGTHDSLIEAGTFIATLQKRQGLMVACPEEIAYRRNWIDAEQVLKLAQPLAKNAYGQYLRNLLTHQVAW 5ify A 2.25 BS03 UMP B 1 G218 R219 G220 G217 R218 G219 2.7.7.24 A4JC15 ARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDTPRFESMLGDGSQWGMNIQYATQPSPDGLAQAFVIGRDFVGNEPSALILGDNIFYGHDLAKQLERASAKDTGATVFAYHVQDPERYGVVEFDREFRAISIEEKPAKPRSSYAVTGLYFYDRQVCDIAADIKPSARGELEITDVNSRYLAAGQLDVELMGRGYAWLDTGTHDSLIEAGTFIATLQKRQGLMVACPEEIAYRRNWIDAEQVLKLAQPLAKNAYGQYLRNLLTHQVAW 5ify B 2.25 BS02 TRH B 1 L8 G10 G11 S12 Q82 P85 D86 G87 L88 L108 D110 Y145 G146 E161 K162 V172 T173 G174 Y176 R194 E196 T200 W223 L8 G10 G11 S12 Q82 P85 D86 G87 L88 L108 D110 Y145 G146 E161 K162 V172 T173 G174 Y176 R194 E196 T200 W223 2.7.7.24 A4JC15 MARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDTPRFESMLGDGSQWGMNIQYATQPSPDGLAQAFVIGRDFVGNEPSALILGDNIFYGHDLAKQLERASAKDTGATVFAYHVQDPERYGVVEFDREFRAISIEEKPAKPRSSYAVTGLYFYDRQVCDIAADIKPSARGELEITDVNSRYLAAGQLDVELMGRGYAWLDTGTHDSLIEAGTFIATLQKRQGLMVACPEEIAYRRNWIDAEQVLKLAQPLAKNAYGQYLRNLLTHQVA 5ify B 2.25 BS03 UMP B 1 I45 Y114 G115 H116 D117 V250 A251 E255 I256 I45 Y114 G115 H116 D117 V250 A251 E255 I256 2.7.7.24 A4JC15 MARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDTPRFESMLGDGSQWGMNIQYATQPSPDGLAQAFVIGRDFVGNEPSALILGDNIFYGHDLAKQLERASAKDTGATVFAYHVQDPERYGVVEFDREFRAISIEEKPAKPRSSYAVTGLYFYDRQVCDIAADIKPSARGELEITDVNSRYLAAGQLDVELMGRGYAWLDTGTHDSLIEAGTFIATLQKRQGLMVACPEEIAYRRNWIDAEQVLKLAQPLAKNAYGQYLRNLLTHQVA 5ify C 2.25 BS01 TRH C 1 L8 G10 G11 S12 Q82 P85 D86 G87 L108 D110 Y145 G146 E161 K162 V172 T173 Y176 R194 E196 I199 T200 L7 G9 G10 S11 Q81 P84 D85 G86 L107 D109 Y144 G145 E160 K161 V171 T172 Y175 R193 E195 I198 T199 2.7.7.24 A4JC15 ARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDTPRFESMLGDGSQWGMNIQYATQPSPDGLAQAFVIGRDFVGNEPSALILGDNIFYGHDLAKQLERASAKDTGATVFAYHVQDPERYGVVEFDREFRAISIEEKPAKPRSSYAVTGLYFYDRQVCDIAADIKPSARGELEITDVNSRYLAAGQLDVELMGRGYAWLDTGTHDSLIEAGTFIATLQKRQGLMVACPEEIAYRRNWIDAEQVLKLAQPLAKNAYGQYLRNLLTH 5ify C 2.25 BS02 UMP C 1 I45 Y114 G115 H116 D117 A251 E255 I256 I44 Y113 G114 H115 D116 A250 E254 I255 2.7.7.24 A4JC15 ARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDTPRFESMLGDGSQWGMNIQYATQPSPDGLAQAFVIGRDFVGNEPSALILGDNIFYGHDLAKQLERASAKDTGATVFAYHVQDPERYGVVEFDREFRAISIEEKPAKPRSSYAVTGLYFYDRQVCDIAADIKPSARGELEITDVNSRYLAAGQLDVELMGRGYAWLDTGTHDSLIEAGTFIATLQKRQGLMVACPEEIAYRRNWIDAEQVLKLAQPLAKNAYGQYLRNLLTH 5ify D 2.25 BS02 TRH D 1 L8 G10 G11 Q82 P85 D86 G87 L88 L108 D110 Y145 G146 E161 K162 V172 T173 G174 Y176 T200 L7 G9 G10 Q81 P84 D85 G86 L87 L107 D109 Y144 G145 E160 K161 V171 T172 G173 Y175 T199 2.7.7.24 A4JC15 ARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDTPRFESMLGDGSQWGMNIQYATQPSPDGLAQAFVIGRDFVGNEPSALILGDNIFYGHDLAKQLERASAKDTGATVFAYHVQDPERYGVVEFDREFRAISIEEKPAKPRSSYAVTGLYFYDRQVCDIAADIKPSARGELEITDVNSRYLAAGQLDVELMGRGYAWLDTGTHDSLIEAGTFIATLQKRQGLMVACPEEIAYRRNWIDAEQVLKLAQPLAKNAYGQYLRNLLTHQVAW