2mqo A BS01 NUC B 1 P90 H91 T93 H100 R102 V127 V128 M129 K131 K132 Q134 L136 F165 N167 Y168 S169 T170 I174 S175 P7 H8 T10 H17 R19 V44 V45 M46 K48 K49 Q51 L53 F82 N84 Y85 S86 T87 I91 S92 F2Z3R2 GENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNS 2mqp A BS01 NUC B 1 V191 L193 T195 I196 V222 I223 F224 K226 N227 G228 V229 Q230 M232 E234 E263 Y264 A265 K266 P267 T268 R269 L270 N271 V272 F273 K274 T279 V18 L20 T22 I23 V49 I50 F51 K53 N54 G55 V56 Q57 M59 E61 E90 Y91 A92 K93 P94 T95 R96 L97 N98 V99 F100 K101 T106 F2Z3R2 QKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQG 2mqq A BS01 NUC B 1 M382 Y384 K410 M412 K413 S414 K415 A418 M420 N447 V450 S451 K452 Q453 A455 I456 M457 P458 G459 Q460 S461 Y462 S470 M11 Y13 K39 M41 K42 S43 K44 A47 M49 N76 V79 S80 K81 Q82 A84 I85 M86 P87 G88 Q89 S90 Y91 S99 Q5U1Y5 YGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKMNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS 2mqq A BS02 NUC C 1 R478 N479 R481 Q487 K490 R492 H501 F503 N504 K530 F532 S533 K535 R538 L543 Y573 T574 K576 C578 F579 S580 T581 A582 H584 R107 N108 R110 Q116 K119 R121 H130 F132 N133 K159 F161 S162 K164 R167 L172 Y202 T203 K205 C207 F208 S209 T210 A211 H213 Q5U1Y5 YGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKMNVCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS 4qo5 A 1.70 BS01 HEC A 1 C51 C54 H55 C107 Y108 H111 H124 F125 F127 I129 P131 S213 V218 L220 V221 C23 C26 H27 C79 Y80 H83 H96 F97 F99 I101 P103 S185 V190 L192 V193 A8AB33 ANTVNLQEAVAKLKNVSPQTKTCLSCHISVTPGIVADWLKSKMAHVTPAEAWQKPALEREVSTPLDEIPANLRNVVVGCYECHGLNPEKHPDTIDHFGFKIHPIVTPNDCAVCHRTEVEQYSKSSKAWAYYNLMHNPIYRALVNASTMFTCMGKTFGGERTSQETSCLACHGTVVKVVGTVDTISHGIPVTLVKYEGYPNHGVGRVNPDGSLGACTACHPRHSFDIEIARSPYTCGQCHLDPDVPAFNVWKESKHGNIWFMHHKKYNMKAPAWKPGADFTAPTCATCHMSLLVNPVTGEVIAERTHNVDTRLWVRLFGLIYAHPMPRTGQHFKLSVEAMPESTAEALAKQGLTIAKALVGVKLPMPISLAPDIKTGKFLYATLPDGSPGLISEEEMAKRREQMVKICSACHNTEYAEYRMRLLDTQIEETNKATLKTTVLLLKAWQSGLAHVDLAKPVTLFDEYIEKLWVESWLFYSNSIRYGTAMNGQDWTTFKRGWYQLTKDIEHMKTLLRLWEAARAA 4qo5 A 1.70 BS02 HEC A 2 H55 I62 W66 M71 V105 G106 C107 C110 H111 P131 V133 Y226 H229 R233 T244 R249 H250 F252 H27 I34 W38 M43 V77 G78 C79 C82 H83 P103 V105 Y198 H201 R205 T216 R221 H222 F224 A8AB33 ANTVNLQEAVAKLKNVSPQTKTCLSCHISVTPGIVADWLKSKMAHVTPAEAWQKPALEREVSTPLDEIPANLRNVVVGCYECHGLNPEKHPDTIDHFGFKIHPIVTPNDCAVCHRTEVEQYSKSSKAWAYYNLMHNPIYRALVNASTMFTCMGKTFGGERTSQETSCLACHGTVVKVVGTVDTISHGIPVTLVKYEGYPNHGVGRVNPDGSLGACTACHPRHSFDIEIARSPYTCGQCHLDPDVPAFNVWKESKHGNIWFMHHKKYNMKAPAWKPGADFTAPTCATCHMSLLVNPVTGEVIAERTHNVDTRLWVRLFGLIYAHPMPRTGQHFKLSVEAMPESTAEALAKQGLTIAKALVGVKLPMPISLAPDIKTGKFLYATLPDGSPGLISEEEMAKRREQMVKICSACHNTEYAEYRMRLLDTQIEETNKATLKTTVLLLKAWQSGLAHVDLAKPVTLFDEYIEKLWVESWLFYSNSIRYGTAMNGQDWTTFKRGWYQLTKDIEHMKTLLRLWEAARAA 4qo5 A 1.70 BS03 HEC A 3 K70 M71 V74 T75 P76 A79 K82 E88 V89 V105 C110 L113 V133 C138 C141 H142 C243 F252 I254 K42 M43 V46 T47 P48 A51 K54 E60 V61 V77 C82 L85 V105 C110 C113 H114 C215 F224 I226 A8AB33 ANTVNLQEAVAKLKNVSPQTKTCLSCHISVTPGIVADWLKSKMAHVTPAEAWQKPALEREVSTPLDEIPANLRNVVVGCYECHGLNPEKHPDTIDHFGFKIHPIVTPNDCAVCHRTEVEQYSKSSKAWAYYNLMHNPIYRALVNASTMFTCMGKTFGGERTSQETSCLACHGTVVKVVGTVDTISHGIPVTLVKYEGYPNHGVGRVNPDGSLGACTACHPRHSFDIEIARSPYTCGQCHLDPDVPAFNVWKESKHGNIWFMHHKKYNMKAPAWKPGADFTAPTCATCHMSLLVNPVTGEVIAERTHNVDTRLWVRLFGLIYAHPMPRTGQHFKLSVEAMPESTAEALAKQGLTIAKALVGVKLPMPISLAPDIKTGKFLYATLPDGSPGLISEEEMAKRREQMVKICSACHNTEYAEYRMRLLDTQIEETNKATLKTTVLLLKAWQSGLAHVDLAKPVTLFDEYIEKLWVESWLFYSNSIRYGTAMNGQDWTTFKRGWYQLTKDIEHMKTLLRLWEAARAA 4qo5 A 1.70 BS04 HEC A 4 L161 Y167 L170 V171 S174 S194 C195 C198 H199 C266 H267 V272 R343 F345 H359 Y510 L133 Y139 L142 V143 S146 S166 C167 C170 H171 C238 H239 V244 R315 F317 H331 Y482 A8AB33 ANTVNLQEAVAKLKNVSPQTKTCLSCHISVTPGIVADWLKSKMAHVTPAEAWQKPALEREVSTPLDEIPANLRNVVVGCYECHGLNPEKHPDTIDHFGFKIHPIVTPNDCAVCHRTEVEQYSKSSKAWAYYNLMHNPIYRALVNASTMFTCMGKTFGGERTSQETSCLACHGTVVKVVGTVDTISHGIPVTLVKYEGYPNHGVGRVNPDGSLGACTACHPRHSFDIEIARSPYTCGQCHLDPDVPAFNVWKESKHGNIWFMHHKKYNMKAPAWKPGADFTAPTCATCHMSLLVNPVTGEVIAERTHNVDTRLWVRLFGLIYAHPMPRTGQHFKLSVEAMPESTAEALAKQGLTIAKALVGVKLPMPISLAPDIKTGKFLYATLPDGSPGLISEEEMAKRREQMVKICSACHNTEYAEYRMRLLDTQIEETNKATLKTTVLLLKAWQSGLAHVDLAKPVTLFDEYIEKLWVESWLFYSNSIRYGTAMNGQDWTTFKRGWYQLTKDIEHMKTLLRLWEAARAA 4qo5 A 1.70 BS05 HEC A 5 E88 C138 H142 E145 V146 Y149 K154 C243 A245 C246 H247 I254 A257 R258 A313 M317 S318 L319 R332 H334 E60 C110 H114 E117 V118 Y121 K126 C215 A217 C218 H219 I226 A229 R230 A285 M289 S290 L291 R304 H306 A8AB33 ANTVNLQEAVAKLKNVSPQTKTCLSCHISVTPGIVADWLKSKMAHVTPAEAWQKPALEREVSTPLDEIPANLRNVVVGCYECHGLNPEKHPDTIDHFGFKIHPIVTPNDCAVCHRTEVEQYSKSSKAWAYYNLMHNPIYRALVNASTMFTCMGKTFGGERTSQETSCLACHGTVVKVVGTVDTISHGIPVTLVKYEGYPNHGVGRVNPDGSLGACTACHPRHSFDIEIARSPYTCGQCHLDPDVPAFNVWKESKHGNIWFMHHKKYNMKAPAWKPGADFTAPTCATCHMSLLVNPVTGEVIAERTHNVDTRLWVRLFGLIYAHPMPRTGQHFKLSVEAMPESTAEALAKQGLTIAKALVGVKLPMPISLAPDIKTGKFLYATLPDGSPGLISEEEMAKRREQMVKICSACHNTEYAEYRMRLLDTQIEETNKATLKTTVLLLKAWQSGLAHVDLAKPVTLFDEYIEKLWVESWLFYSNSIRYGTAMNGQDWTTFKRGWYQLTKDIEHMKTLLRLWEAARAA 4qo5 A 1.70 BS06 HEC A 6 S153 K154 A157 N160 C198 H199 H229 V231 A245 C246 A257 C263 Q265 C266 H267 C312 H316 V336 D337 L340 R343 H359 S125 K126 A129 N132 C170 H171 H201 V203 A217 C218 A229 C235 Q237 C238 H239 C284 H288 V308 D309 L312 R315 H331 A8AB33 ANTVNLQEAVAKLKNVSPQTKTCLSCHISVTPGIVADWLKSKMAHVTPAEAWQKPALEREVSTPLDEIPANLRNVVVGCYECHGLNPEKHPDTIDHFGFKIHPIVTPNDCAVCHRTEVEQYSKSSKAWAYYNLMHNPIYRALVNASTMFTCMGKTFGGERTSQETSCLACHGTVVKVVGTVDTISHGIPVTLVKYEGYPNHGVGRVNPDGSLGACTACHPRHSFDIEIARSPYTCGQCHLDPDVPAFNVWKESKHGNIWFMHHKKYNMKAPAWKPGADFTAPTCATCHMSLLVNPVTGEVIAERTHNVDTRLWVRLFGLIYAHPMPRTGQHFKLSVEAMPESTAEALAKQGLTIAKALVGVKLPMPISLAPDIKTGKFLYATLPDGSPGLISEEEMAKRREQMVKICSACHNTEYAEYRMRLLDTQIEETNKATLKTTVLLLKAWQSGLAHVDLAKPVTLFDEYIEKLWVESWLFYSNSIRYGTAMNGQDWTTFKRGWYQLTKDIEHMKTLLRLWEAARAA 4qo5 A 1.70 BS07 HEC A 7 C263 H267 A274 F275 W278 H283 C312 C315 H316 L340 W341 V342 R343 L344 F345 M431 M448 Y510 A513 M514 C235 H239 A246 F247 W250 H255 C284 C287 H288 L312 W313 V314 R315 L316 F317 M403 M420 Y482 A485 M486 A8AB33 ANTVNLQEAVAKLKNVSPQTKTCLSCHISVTPGIVADWLKSKMAHVTPAEAWQKPALEREVSTPLDEIPANLRNVVVGCYECHGLNPEKHPDTIDHFGFKIHPIVTPNDCAVCHRTEVEQYSKSSKAWAYYNLMHNPIYRALVNASTMFTCMGKTFGGERTSQETSCLACHGTVVKVVGTVDTISHGIPVTLVKYEGYPNHGVGRVNPDGSLGACTACHPRHSFDIEIARSPYTCGQCHLDPDVPAFNVWKESKHGNIWFMHHKKYNMKAPAWKPGADFTAPTCATCHMSLLVNPVTGEVIAERTHNVDTRLWVRLFGLIYAHPMPRTGQHFKLSVEAMPESTAEALAKQGLTIAKALVGVKLPMPISLAPDIKTGKFLYATLPDGSPGLISEEEMAKRREQMVKICSACHNTEYAEYRMRLLDTQIEETNKATLKTTVLLLKAWQSGLAHVDLAKPVTLFDEYIEKLWVESWLFYSNSIRYGTAMNGQDWTTFKRGWYQLTKDIEHMKTLLRLWEAARAA 4qo5 A 1.70 BS08 HEC A 8 K282 H283 I286 F307 T308 A309 P310 M431 C435 C438 H439 Y443 R447 N515 Q517 K254 H255 I258 F279 T280 A281 P282 M403 C407 C410 H411 Y415 R419 N487 Q489 A8AB33 ANTVNLQEAVAKLKNVSPQTKTCLSCHISVTPGIVADWLKSKMAHVTPAEAWQKPALEREVSTPLDEIPANLRNVVVGCYECHGLNPEKHPDTIDHFGFKIHPIVTPNDCAVCHRTEVEQYSKSSKAWAYYNLMHNPIYRALVNASTMFTCMGKTFGGERTSQETSCLACHGTVVKVVGTVDTISHGIPVTLVKYEGYPNHGVGRVNPDGSLGACTACHPRHSFDIEIARSPYTCGQCHLDPDVPAFNVWKESKHGNIWFMHHKKYNMKAPAWKPGADFTAPTCATCHMSLLVNPVTGEVIAERTHNVDTRLWVRLFGLIYAHPMPRTGQHFKLSVEAMPESTAEALAKQGLTIAKALVGVKLPMPISLAPDIKTGKFLYATLPDGSPGLISEEEMAKRREQMVKICSACHNTEYAEYRMRLLDTQIEETNKATLKTTVLLLKAWQSGLAHVDLAKPVTLFDEYIEKLWVESWLFYSNSIRYGTAMNGQDWTTFKRGWYQLTKDIEHMKTLLRLWEAARAA 4qo5 A 1.70 BS09 CA A 1 H479 T487 D490 E491 E494 H451 T459 D462 E463 E466 A8AB33 ANTVNLQEAVAKLKNVSPQTKTCLSCHISVTPGIVADWLKSKMAHVTPAEAWQKPALEREVSTPLDEIPANLRNVVVGCYECHGLNPEKHPDTIDHFGFKIHPIVTPNDCAVCHRTEVEQYSKSSKAWAYYNLMHNPIYRALVNASTMFTCMGKTFGGERTSQETSCLACHGTVVKVVGTVDTISHGIPVTLVKYEGYPNHGVGRVNPDGSLGACTACHPRHSFDIEIARSPYTCGQCHLDPDVPAFNVWKESKHGNIWFMHHKKYNMKAPAWKPGADFTAPTCATCHMSLLVNPVTGEVIAERTHNVDTRLWVRLFGLIYAHPMPRTGQHFKLSVEAMPESTAEALAKQGLTIAKALVGVKLPMPISLAPDIKTGKFLYATLPDGSPGLISEEEMAKRREQMVKICSACHNTEYAEYRMRLLDTQIEETNKATLKTTVLLLKAWQSGLAHVDLAKPVTLFDEYIEKLWVESWLFYSNSIRYGTAMNGQDWTTFKRGWYQLTKDIEHMKTLLRLWEAARAA 4rzt A 3.10 BS01 40J A 1 L73 A75 P76 I79 N125 Y126 P127 L148 T149 F161 D193 R197 W220 N246 D274 Q291 L296 L14 A16 P17 I20 N66 Y67 P68 L89 T90 F102 D134 R138 W161 N187 D215 Q232 L237 QSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLTASDQTPLNSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVDARLRLAGWHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLARQVSRLESGQ 4rzt D 3.10 BS01 40J D 1 L73 A75 P76 I79 N125 Y126 P127 L148 F161 D193 R197 W220 N246 D274 F293 L296 L12 A14 P15 I18 N64 Y65 P66 L87 F100 D132 R136 W159 N185 D213 F232 L235 LLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLTASDQTPLNSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVDARLRLAGWHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLARQVSRL 4tly B 2.10 BS05 CA B 5 E91 S94 D107 E243 E87 S90 D103 E239 Q05JF3 26416891 DFPEYDGVDRVVNVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMDELILELAAQVLEDKGVGFGMVDSEKDAAVAKKLGLTEEDSVYVFKGDEVIEYDGEFSADTLVEFLLDVLEDPVELIEGERELQAFENIEDDNKLIGYFKNKDSEHYKAYEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPVTIPDKPNSEEEIVSFVEAHKRSTLRKLKPESMYETWEDDLDGIHIVAFAEETDPDGYEFLETLKAVAQDNTDNPDLSIIWIDPDDFPLLVPYWEKTFNIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEG 4txk A 2.88 BS01 FAD A 1 G91 G93 P94 C95 V113 E114 K115 R116 R121 N123 L125 I157 V179 K180 F181 A217 A218 G219 Y293 G392 D393 W400 G405 G85 G87 P88 C89 V107 E108 K109 R110 R115 N117 L119 I151 V173 K174 F175 A211 A212 G213 Y287 G386 D387 W394 G399 1.14.13.- Q8VDP3 TNPAHDHFETFVQAQLCQDVLSSFQGLCRALGVESGGGLSQYHKIKAQLNYWSAKSLWAKLDKRASQPVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLVEKRIKFSRHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVKFTGLQPPPRKGSGWRAQLQPNPPAQLASYEFDVLISAAGGKFVPEGFTIREMRGKLAIGITANFVNGRTVEETQVPEISGVARIYNQKFFQSLLKATGIDLENIVYYKDETHYFVMTAKKQCLLRLGVLRQDLSETDQLLGKANVVPEALQRFARAAADFATHGKLGKLEFAQDARGRPDVAAFDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMVKRWAEGAGPLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVQDLYDMMDGTEELLHWCQEQTAGFPGVHVTDFSSSWADGLALCALVHHLQPGLLQGMGALEATTWALRVAEHELGITPVLSAQAVMAGSDPLGLIAYLSHFHSAFKNT 4wfn A 3.54 BS01 MG A 1 H233 G234 H221 G222 Q9RXJ9 RRQMTTADFSGLTKKRPEKALTEALPKTGGRNNRGRITSRFIGGGHKRLYRIIDFKRRDKSGVNAKVAAIEYDPNRSARIALLHYADGEKRYILAPEGLTVGATVNAGPEAEPKLGNALPLRFVPVGAVVHALELVPGKGAQLARSAGTSVQVQGKESDYVIVRLPSGELRRVHSECYATIGAVGNAEHKNIVLGKAGRSRWLGRKPHQRGSAMNPVDHPHGGGEGRTGAGRVPVTPWGKPTKGLKTRRKRKTSDRFIVT 4wfn D 3.54 BS01 NUC Y 1 K5 S24 V25 M26 A27 R30 Q63 K64 I66 I67 K69 V89 T90 R92 K3 S22 V23 M24 A25 R28 Q61 K62 I64 I65 K67 V87 T88 R90 Q9RXJ0 QLKTKYNDQVRPALMQQFGYSSVMAVPRIEKIVVNEGLGSSKEDSKAIDKAAKELALITLQKPIITKAKKSISNFKLRQGMPVGIKVTLRGERMYVFLEKLINIGLPRIRDFRGINPNAFDGRGNYNLGIKEQLIFPEITYDMVDKTRGMDITIVTTAKTDEEARALLQSMGLPFRK 4wfn J 3.54 BS01 NUC Y 1 T19 G20 D21 E39 K99 T14 G15 D16 E34 K94 Q9RXJ5 KRTKFRKQFRGRMTGDAKGGDYVAFGDYGLIAMEPAWIKSNQIEACRIVMSRHFRRGGKIYIRIFPDKPVTKKPAETRMGKGKGAVEYWVSVVKPGRVMFEVAGVTEEQAKEAFRLAGHKLPIQTKMVKREVYDEA 4wfn K 3.54 BS01 MG K 1 H3 K5 H1 K3 Q9RSJ5 HGKAGRKLNRNSSARVALARAQATALLREGRIQTTLTKAKELRPFVEQLITTAKGGDLHSRRLVAQDIHDKDVVRKVMDEVAPKYAERPGGYTRILRVGTRRGDGVTMALIEL 4wfn K 3.54 BS02 MG K 2 G4 K5 G2 K3 Q9RSJ5 HGKAGRKLNRNSSARVALARAQATALLREGRIQTTLTKAKELRPFVEQLITTAKGGDLHSRRLVAQDIHDKDVVRKVMDEVAPKYAERPGGYTRILRVGTRRGDGVTMALIEL 4wfn L 3.54 BS01 NUC Y 1 K16 R28 S30 Y32 S34 S35 H37 Y39 Q41 G48 Q49 T50 A53 S55 A57 K64 T65 Y94 K95 H97 G98 R99 K9 R21 S23 Y25 S27 S28 H30 Y32 Q34 G41 Q42 T43 A46 S48 A50 K57 T58 Y87 K88 H90 G91 R92 Q9RSL2 RRKLRTRRKVRTTTAASGRLRLSVYRSSKHIYAQIIDDSRGQTLAAASSAALKSGNKTDTAAAVGKALAAAAAEKGIKQVVFDRGSYKYHGRVKALADAAREGG 4wfn S 3.54 BS01 NUC Y 1 A20 V22 Y24 N25 N29 K67 R74 I79 H80 D82 Y84 V92 A20 V22 Y24 N25 N29 K67 R74 I79 H80 D82 Y84 V92 Q9RX88 MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR 4wkk A 1.85 BS01 3Q8 A 1 C20 L164 Y166 Y188 F193 G196 D197 I198 P199 A202 Y206 R244 V246 S247 V249 H250 Y253 M257 S262 S264 H280 I459 P461 C4 L148 Y150 Y172 F177 G180 D181 I182 P183 A186 Y190 R228 V230 S231 V233 H234 Y237 M241 S246 S248 H264 I443 P445 Q7CY45 LDSCGAEPIHIPGAIQEHGALLVLSAREFSVVQASDNLANYIGVDLPIGAVATEANLPFISVLSAWYSGAASNFRYAWAEKKLDVSAHRSGTLVILEVEKAGVGESAEKLMGELTSLAKYLNSAPSLEDALFRTAQLVSSISGHDRTLIYDFGLDWSGHVVAEAGSGALPSYLGLRFPAGDIPPQARQLYTINRLRMIPDVDYKPVPIRPEVNAETGAVLDMSFSQLRSVSPVHLEYMRNMGTAASMSVSIVVNGALWGLIACHHATPHSVSLAVREACDFAAQLLSMRIAMEQSSQDASRRVELGHIQARLLKGMAAAAAWVDGLLGGEGEREDLLKQVGADGAALVLGDDYELVGNTPSREQVEELILWLGEREIADVFATDNLAGNYPTAAAYASVASGIIAMRVSELHGSWLIWFRPEVIKTVRWGGDPHKTVQESGRIHPRKSFEIWKEQLRNTSFPWSEPELAAARELRGAIIGIVLRKTEE 4wkk A 1.85 BS02 CA A 1 D167 F168 D151 F152 Q7CY45 LDSCGAEPIHIPGAIQEHGALLVLSAREFSVVQASDNLANYIGVDLPIGAVATEANLPFISVLSAWYSGAASNFRYAWAEKKLDVSAHRSGTLVILEVEKAGVGESAEKLMGELTSLAKYLNSAPSLEDALFRTAQLVSSISGHDRTLIYDFGLDWSGHVVAEAGSGALPSYLGLRFPAGDIPPQARQLYTINRLRMIPDVDYKPVPIRPEVNAETGAVLDMSFSQLRSVSPVHLEYMRNMGTAASMSVSIVVNGALWGLIACHHATPHSVSLAVREACDFAAQLLSMRIAMEQSSQDASRRVELGHIQARLLKGMAAAAAWVDGLLGGEGEREDLLKQVGADGAALVLGDDYELVGNTPSREQVEELILWLGEREIADVFATDNLAGNYPTAAAYASVASGIIAMRVSELHGSWLIWFRPEVIKTVRWGGDPHKTVQESGRIHPRKSFEIWKEQLRNTSFPWSEPELAAARELRGAIIGIVLRKTEE 4wkz A 1.79 BS01 CA A 1 D177 K179 D181 L196 D201 D174 K176 D178 L193 D198 A0AEF5 VTSAVKTQYVEIESVMGFYFNTEDKFDTAQIKKAVLHTVYNEGYTDDGVAVVLREYESEPVDITAELTFGDATPANTYKAVENKFDYEIPVYYNNATLKDAEGNDATVTVYIGLKGDTDLNNIVDGRDATATLTYYAATSTDGKDATTVALSPSTLVGGNPESVYDDFSAFLSDVKVDAGKELTRFAKKAERLIDGRDASSILTFYTKSSVDQYKDMAANEPNKLWDIVTA 4wml A 1.73 BS01 PPC A 1 A74 Y75 K76 K106 D131 D132 V133 M134 T135 A136 G137 T138 A139 A73 Y74 K75 K105 D123 D124 V125 M126 T127 A128 G129 T130 A131 2.4.2.10 P13298 IMLEDYQKNFLELAIECQALRFGSFKLKSGRESPYFFNLGLFNTGKLLSNLATAYAIAIIQSDLKFDVIFGPAYKGIPLAAIVCVKLAEIGGSKFQNIQYAFNRKEGIIVGSALENKRILIIDDVMTAGTAINEAFEIISNAKGQVVGSIIALDRQEVVSTDDKEGLSATQTVSKKYGIPVLSIVSLIHIITYLEGRITAEEKSKIEQYLQTYGAS 4wn3 A 1.80 BS01 3R3 A 1 Y75 K76 D131 D132 V133 M134 T135 A136 G137 T138 A139 Y74 K75 D127 D128 V129 M130 T131 A132 G133 T134 A135 2.4.2.10 P13298 IMLEDYQKNFLELAIECQALRFGSFKLKSGRESPYFFNLGLFNTGKLLSNLATAYAIAIIQSDLKFDVIFGPAYKGIPLAAIVCVKLAEIGGSKFQNIQYAFNRKEAKDGGIIVGSALENKRILIIDDVMTAGTAINEAFEIISNAKGQVVGSIIALDRQEVVSTDDKEGLSATQTVSKKYGIPVLSIVSLIHIITYLEGRITAEEKSKIEQYLQTYGAS 4wrk A 2.90 BS01 DUP A 1 R64 S65 G66 R63 S64 G65 Q8SDV3 TNTLQVRLLSENARMPERNHKTDAGYDIFSAETVVLEPQEKAVIKTDVAVSIPEGYVGLLTSRSGVSSKTHLVIETGKIDAGYHGNLGINIKNNAIASNGYITPGVFDIKGEIDLSDAIRQYGTYQINEGDKLAQLVIVPIWTPELKQVEEFESVSER 4wrk D 2.90 BS03 MG D 1 D28 Q136 D26 Q134 Q8SDV3 NTLQVRLLSENARMPERNHKTDAGYDIFSAETVVLEPQEKAVIKTDVAVSIPEGYVGLLTSRSGVSSKTHLVIETGKIDAGYHGNLGINIKNNAIASNGYITPGVFDIKGEIDLSDAIRQYGTYQINEGDKLAQLVIVPIWTPELKQVEEFES 4wtq A 1.80 BS01 CU A 1 H228 C285 H290 H186 C243 H248 1.10.3.2 B5HSR1 GEVRRIKLYAERLADGQMGYGLEKGRATIPGPLIELNEGDTLHIEFENTMDVRASLHVHGLDYEVSSDGTTLNKSDVEPGGTRTYTWRTHAPGRRSDGTWRAGSAGYWHYHDHVVGTEHGTGGIRKGLYGPVIVRRKGDVLPDATHTIVFNDMLINNRPAHSGPNFEATVGDRVEFVMITHGEYYHTFHMHGHRWADNRTGMLTGPDDPSQVVDNKIVGPADSFGFQVIAGEGVGAGAWMYHCHVQSHSDMGLVGLFLVKKTDGTIPGYE 4wtq B 1.80 BS01 O A 1 H231 H233 H284 H286 H189 H191 H242 H244 1.10.3.2 B5HSR1 GEVRRIKLYAERLADGQMGYGLEKGRATIPGPLIELNEGDTLHIEFENTMDVRASLHVHGLDYEVSSDGTTLNKSDVEPGGTRTYTWRTHAPGRRSDGTWRAGSAGYWHYHDHVVGTEHGTGGIRKGLYGPVIVRRKGDVLPDATHTIVFNDMLINNRPAHSGPNFEATVGDRVEFVMITHGEYYHTFHMHGHRWADNRTGMLTGPDDPSQVVDNKIVGPADSFGFQVIAGEGVGAGAWMYHCHVQSHSDMGLVGLFLVKKTDGTIPGY 4wxr A 2.42 BS01 3VZ A 1 V232 T254 G255 T269 G271 K272 A275 W501 Y502 E503 V43 T61 G62 T76 G78 K79 A82 W301 Y302 E303 A1Z092 PPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKDPNIRTGVRTITTGSPITYSTYGKFLADGGCSAYDIIICDECHSTDATSILGIGTVLDQAETAGARLVVLATATPPGSVTVSHPNIEEVALSTTGEIPFYGKAIPLEVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGLDVSVIPTSGDVVVVSTDATGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVAPGERPSGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLTHIDAHFLSQTKQSGENFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMTCMSADL 4x2d A 2.50 BS01 ATP A 1 A35 I117 E160 H163 D167 G168 N169 G170 R171 R174 Y199 R200 L203 N204 A29 I111 E154 H157 D161 G162 N163 G164 R165 R168 Y193 R194 L197 N198 C9YJ22 SFLDKLIETKNSLYNVLKHNFLYHANKIAGSTFTTEALALLLDKNVVTGRHTLDDVQETVNSSYVFDTVIDSLKEKITHNFLRNLHSSLIFNTTLHSRGMAGIYKTIPNMILGTDVSIAQPFEVEPKLDELIEWYYSQSEVSIKVIAEFHYRFELIHPFQDGNGRIGRFVMLKQMLENNLPIKIVSWDSEDLYRNSLNSCSLGNYVPLIEYLSSLEDFREVYKMLWK 4x3c A 2.60 BS01 TNH A 1 Y70 D72 E73 Q74 W84 Y121 E199 F330 Y334 W432 I439 H440 Y442 Y69 D71 E72 Q73 W83 Y120 E198 F329 Y333 W431 I438 H439 Y441 3.1.1.7 P04058 DHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 4x6t A 1.40 BS01 3Y6 A 1 C83 S84 K87 R115 S116 I117 S142 E182 P183 R187 G252 T253 G254 D255 C41 S42 K45 R73 S74 I75 S100 E140 P141 R145 G210 T211 G212 D213 3.5.2.6 P9WKD3 ALADRFAELERRYDARLGVYVPATGTTAAIEYRADERFAFCSTFKAPLVAAVLHQNPLTHLDKLITYTSDDIRSISPVAQQHVATGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDAEEPELARDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAATCVAGVLA 4x6z 2 2.70 BS01 MG 2 1 K210 D212 K218 D220 3.4.25.1 P30657 TQQPIVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIERLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGVQSNGDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVNAMRVLYYRDARSSRNFSLAIIDKNTGLTFKKNLQVENMKWDFAKDIKGYGTQKI 4x6z F 2.70 BS01 III e 1 A28 Q31 G32 S33 R51 Q60 K62 A75 G76 A26 Q29 G30 S31 R49 Q58 K60 A73 G74 3.4.25.1 P40302 RNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI 4x6z H 2.70 BS01 MG H 1 T1 G47 T1 G47 3.4.25.1 P38624 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL 4x6z I 2.70 BS01 MG J 1 C31 A32 C31 A32 3.4.25.1 P25043 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNIC 4x6z J 2.70 BS01 MG J 1 I121 E123 I129 E131 3.4.25.1 P25451 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 4x6z Q 2.70 BS01 MG Q 1 N97 Y98 N96 Y97 3.4.25.1 P23638 GSRRYDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTDSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIKDILVKTGIT 4x6z S 2.70 BS01 MG S 1 K194 K235 K186 K227 3.4.25.1 P32379 DRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELIKELKEKEAAE 4x6z T 2.70 BS01 III a 1 A28 Q31 G32 S33 R51 K62 A75 G76 A26 Q29 G30 S31 R49 K60 A73 G74 3.4.25.1 P40302 RNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI 4x6z V 2.70 BS01 MG V 1 L93 T94 L93 T94 3.4.25.1 P38624 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL 4x6z Y 2.70 BS01 MG X 1 V125 E126 V126 E127 3.4.25.1 P22141 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDFQ 4x9d A 1.50 BS01 U5P A 1 N47 Y48 K63 N32 Y33 K48 Q58830 NFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDYIEY 4x9d A 1.50 BS02 U5P B 1 Y48 F62 H64 Y33 F47 H49 Q58830 NFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDYIEY 4x9d C 1.50 BS01 U5P C 1 E18 N47 Y48 K63 H64 E3 N32 Y33 K48 H49 Q58830 NFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDYIEY 4x9d E 1.50 BS01 U5P E 1 N47 Y48 F62 K63 H64 N32 Y33 F47 K48 H49 Q58830 NFEYARRLNGKKVKIFLRNGEVLDAEVTGVSNYEIMVKVGDRNLLVFKHAIDYIEY 4xbj A 2.25 BS01 IN5 A 1 V32 K34 Y38 R129 H159 A193 S194 R209 G211 I212 Y343 V30 K32 Y36 R127 H157 A191 S192 R207 G209 I210 Y341 5.1.1.1 P0A6B4 AATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHFARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSPLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGFGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYVD 4xbj A 2.25 BS02 IN5 B 1 Y255 A302 M303 Y253 A300 M301 5.1.1.1 P0A6B4 AATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHFARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSPLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGFGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYVD 4xbj B 2.25 BS01 IN5 A 1 Y255 A302 M303 D304 Y254 A301 M302 D303 5.1.1.1 P0A6B4 QAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHFARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSPLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGFGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYVD 4xbo A 2.60 BS01 SAH A 1 T79 S80 A81 F113 G114 R115 G119 V132 A133 I134 S141 S142 L143 A148 T79 S80 A81 F113 G114 R115 G119 V132 A133 I134 S141 S142 L143 A148 2.1.1.200 P0AE01 26202969 MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVAEAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAWLATQTPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTRARPESQELNILRGILASIEQ 4xbo B 2.60 BS01 SAH B 1 T79 S80 A81 F113 G114 R115 R117 G119 V132 A133 I134 S141 S142 L143 L145 A148 T72 S73 A74 F106 G107 R108 R110 G112 V125 A126 I127 S134 S135 L136 L138 A141 2.1.1.200 P0AE01 26202969 MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVAEAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAWLATQENETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTRARPESQELNILRGILASIEQQN 4xef A 2.50 BS01 III B 1 R875 Y881 M885 R889 L892 K895 H981 A984 K988 L991 R6 Y12 M16 R20 L23 K26 H112 A115 K119 L122 2.7.10.2 Q14289 MANLDRTDDLVYLNVMELVRAVLELKNELSQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEEAKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAH 4xef A 2.50 BS02 III C 1 V907 K911 R918 I921 G922 D925 N947 L950 I954 R958 V38 K42 R49 I52 G53 D56 N78 L81 I85 R89 2.7.10.2 Q14289 MANLDRTDDLVYLNVMELVRAVLELKNELSQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEEAKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAH 4xef D 2.50 BS01 III E 1 R875 Y881 M885 V888 L892 K895 H981 A984 K988 L991 R5 Y11 M15 V18 L22 K25 H111 A114 K118 L121 2.7.10.2 Q14289 ANLDRTDDLVYLNVMELVRAVLELKNELSQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEEAKRQMLTASHTLAVDAKNLLDAVDQAKVLANLA 4xef D 2.50 BS02 III F 1 V907 G914 L917 R918 I921 N947 L950 M957 V37 G44 L47 R48 I51 N77 L80 M87 2.7.10.2 Q14289 ANLDRTDDLVYLNVMELVRAVLELKNELSQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEEAKRQMLTASHTLAVDAKNLLDAVDQAKVLANLA 4xkm A 2.10 BS01 MN A 1 E234 E270 H273 D298 D341 E231 E267 H270 D295 D338 5.3.1.5 Q8A9M2 KEFFPGIEKIKFEGKDSKNPMAFRYYDAEKVINGKKMKDWLRFAMAWWHTLCAEGGDQFGGGTKQFPWNGNADAIQAAKDKMDAGFEFMQKMGIEYYCFHDVDLVSEGASVEEYEANLKEIVAYAKQKQAETGIKLLWGTANVFGHARYMNGAATNPDFDVVARAAVQIKNAIDATIELGGENYVFWGGREGYMSLLNTDQKREKEHLAQMLTIARDYARARGFKGTFLIEPKPMEPTKHQYDVDTETVIGFLKAHGLDKDFKVNIEVNHATLAGHTFEHELAVAVDNGMLGSIDANRGDYQNGWDTDQFPIDNYELTQAMMQIIRNGGLGTGGTNFDAKTRRNSTDLEDIFIAHIAGMDAMARALESAAALLDESPYKKMLADRYASFDGGKGKEFEDGKLTLEDVVAYAKTKGEPKQTSGKQELYEAILNMYC 4xkm A 2.10 BS02 MN A 2 E270 H273 D309 D311 E267 H270 D306 D308 5.3.1.5 Q8A9M2 KEFFPGIEKIKFEGKDSKNPMAFRYYDAEKVINGKKMKDWLRFAMAWWHTLCAEGGDQFGGGTKQFPWNGNADAIQAAKDKMDAGFEFMQKMGIEYYCFHDVDLVSEGASVEEYEANLKEIVAYAKQKQAETGIKLLWGTANVFGHARYMNGAATNPDFDVVARAAVQIKNAIDATIELGGENYVFWGGREGYMSLLNTDQKREKEHLAQMLTIARDYARARGFKGTFLIEPKPMEPTKHQYDVDTETVIGFLKAHGLDKDFKVNIEVNHATLAGHTFEHELAVAVDNGMLGSIDANRGDYQNGWDTDQFPIDNYELTQAMMQIIRNGGLGTGGTNFDAKTRRNSTDLEDIFIAHIAGMDAMARALESAAALLDESPYKKMLADRYASFDGGKGKEFEDGKLTLEDVVAYAKTKGEPKQTSGKQELYEAILNMYC 4xkm B 2.10 BS02 MN B 2 E270 H273 N300 D309 D311 E267 H270 N297 D306 D308 5.3.1.5 Q8A9M2 KEFFPGIEKIKFEGKDSKNPMAFRYYDAEKVINGKKMKDWLRFAMAWWHTLCAEGGDQFGGGTKQFPWNGNADAIQAAKDKMDAGFEFMQKMGIEYYCFHDVDLVSEGASVEEYEANLKEIVAYAKQKQAETGIKLLWGTANVFGHARYMNGAATNPDFDVVARAAVQIKNAIDATIELGGENYVFWGGREGYMSLLNTDQKREKEHLAQMLTIARDYARARGFKGTFLIEPKPMEPTKHQYDVDTETVIGFLKAHGLDKDFKVNIEVNHATLAGHTFEHELAVAVDNGMLGSIDANRGDYQNGWDTDQFPIDNYELTQAMMQIIRNGGLGTGGTNFDAKTRRNSTDLEDIFIAHIAGMDAMARALESAAALLDESPYKKMLADRYASFDGGKGKEFEDGKLTLEDVVAYAKTKGEPKQTSGKQELYEAILNMYC 4xkm D 2.10 BS01 MN D 1 E234 E270 D298 D341 E231 E267 D295 D338 5.3.1.5 Q8A9M2 KEFFPGIEKIKFEGKDSKNPMAFRYYDAEKVINGKKMKDWLRFAMAWWHTLCAEGGDQFGGGTKQFPWNGNADAIQAAKDKMDAGFEFMQKMGIEYYCFHDVDLVSEGASVEEYEANLKEIVAYAKQKQAETGIKLLWGTANVFGHARYMNGAATNPDFDVVARAAVQIKNAIDATIELGGENYVFWGGREGYMSLLNTDQKREKEHLAQMLTIARDYARARGFKGTFLIEPKPMEPTKHQYDVDTETVIGFLKAHGLDKDFKVNIEVNHATLAGHTFEHELAVAVDNGMLGSIDANRGDYQNGWDTDQFPIDNYELTQAMMQIIRNGGLGTGGTNFDAKTRRNSTDLEDIFIAHIAGMDAMARALESAAALLDESPYKKMLADRYASFDGGKGKEFEDGKLTLEDVVAYAKTKGEPKQTSGKQELYEAILNMYC 4xkm D 2.10 BS02 MN D 2 E270 H273 D309 D311 D341 E267 H270 D306 D308 D338 5.3.1.5 Q8A9M2 KEFFPGIEKIKFEGKDSKNPMAFRYYDAEKVINGKKMKDWLRFAMAWWHTLCAEGGDQFGGGTKQFPWNGNADAIQAAKDKMDAGFEFMQKMGIEYYCFHDVDLVSEGASVEEYEANLKEIVAYAKQKQAETGIKLLWGTANVFGHARYMNGAATNPDFDVVARAAVQIKNAIDATIELGGENYVFWGGREGYMSLLNTDQKREKEHLAQMLTIARDYARARGFKGTFLIEPKPMEPTKHQYDVDTETVIGFLKAHGLDKDFKVNIEVNHATLAGHTFEHELAVAVDNGMLGSIDANRGDYQNGWDTDQFPIDNYELTQAMMQIIRNGGLGTGGTNFDAKTRRNSTDLEDIFIAHIAGMDAMARALESAAALLDESPYKKMLADRYASFDGGKGKEFEDGKLTLEDVVAYAKTKGEPKQTSGKQELYEAILNMYC 4xkm G 2.10 BS02 MN G 2 E270 H273 N300 D309 D311 D341 E267 H270 N297 D306 D308 D338 5.3.1.5 Q8A9M2 KEFFPGIEKIKFEGKDSKNPMAFRYYDAEKVINGKKMKDWLRFAMAWWHTLCAEGGDQFGGGTKQFPWNGNADAIQAAKDKMDAGFEFMQKMGIEYYCFHDVDLVSEGASVEEYEANLKEIVAYAKQKQAETGIKLLWGTANVFGHARYMNGAATNPDFDVVARAAVQIKNAIDATIELGGENYVFWGGREGYMSLLNTDQKREKEHLAQMLTIARDYARARGFKGTFLIEPKPMEPTKHQYDVDTETVIGFLKAHGLDKDFKVNIEVNHATLAGHTFEHELAVAVDNGMLGSIDANRGDYQNGWDTDQFPIDNYELTQAMMQIIRNGGLGTGGTNFDAKTRRNSTDLEDIFIAHIAGMDAMARALESAAALLDESPYKKMLADRYASFDGGKGKEFEDGKLTLEDVVAYAKTKGEPKQTSGKQELYEAILNMYC 4y32 A 1.70 BS01 III C 1 K49 R56 R129 Y130 L174 N175 V178 Y181 E182 L222 N226 W230 K54 R61 R134 Y135 L178 N179 V182 Y185 E186 L226 N230 W234 P31947 26537010 GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 4y32 A 1.70 BS02 49F C 1 N42 S45 V46 F119 K122 N47 S50 V51 F124 K127 P31947 26537010 GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 4y3b A 1.80 BS02 49F C 1 N42 S45 V46 F119 N47 S50 V51 F118 P31947 26537010 GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 4ypq A 2.32 BS01 4F1 A 1 W317 A321 L324 T325 I328 Q329 L483 Q484 Q487 A496 A497 F498 Y502 L505 F506 W53 A57 L60 T61 I64 Q65 L219 Q220 Q223 A232 A233 F234 Y238 L241 F242 P51449 26640126 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 4yz0 A 1.15 BS01 CA A 1 Q37 Q39 E84 D107 Q42 Q44 E89 D112 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSQNQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yz0 A 1.15 BS02 CA A 2 Q39 E84 D85 Q44 E89 D90 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSQNQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yz0 A 1.15 BS05 X1X A 1 D107 K130 R133 K160 D112 K135 R138 K165 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSQNQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yz0 A 1.15 BS06 ADA A 1 E84 D107 Q111 R133 N135 G136 E89 D112 Q116 R138 N140 G141 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSQNQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yz0 A 1.15 BS07 ADA A 2 Q39 E84 D85 Q111 N113 N135 Q44 E89 D90 Q116 N118 N140 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSQNQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yz0 A 1.15 BS09 ADA A 3 Q39 E84 D107 Q111 R133 N135 G136 Q44 E89 D112 Q116 R138 N140 G141 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSQNQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yza A 1.25 BS02 CA A 2 E39 D64 E84 D85 E44 D69 E89 D90 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFALNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yza A 1.25 BS05 X1X A 1 D107 K130 R133 D112 K135 R138 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFALNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yza A 1.25 BS06 ADA A 1 E39 E84 D107 R133 N135 G136 E44 E89 D112 R138 N140 G141 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFALNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yza A 1.25 BS07 ADA A 2 E39 E84 D85 N113 N135 E44 E89 D90 N118 N140 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFALNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yzq A 1.48 BS06 ADA A 2 E39 E84 D107 N111 R133 N135 G136 E44 E89 D112 N116 R138 N140 G141 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFNLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yzw A 2.60 BS01 CU A 1 H223 H227 H252 H216 H220 H245 Q8MZM3 MATLTQKFHGLLQHPLEPLFLPKNDGTLFYDLPERFLTSRYSPIGQNLANRFGPNSPATGVPPTVVTIKDLDELPDLTFATWIKRRDSFSLFNPEHRKAAGKLTKLFLDQPNADRLVDVAAYARDRLNAPLFQYALSVALLHRPDTKSVSVPSLLHLFPDQFIDPAAQVRMMEEGSIVLDENRMPIPIPMNYTATDAEPEQRMAFFREDIGVNLHHWHWHLVYPASGPPDVVRKDRRGELFYYMHQQLLARYQIDRYAQGLGRIEPLANLREPVREAYYPKLLRTSNNRTFCPRYPGMTISDVARSADRLEVRIADIESWLPRVLEAIDAGFAVSDDGVRVPLDETRGIDVLGNILERSAISINRNLYGDVHNMGHVLLAFIHDPRGTYLESSGVMGGVATAMRDPIFYRWHKFIDNIFLRNKARLAPYTMAELSNSNVTLEALETQLDRAGGAVNSFVTFWQRSQVDLRAGIDFSAAGSAFVSFTHLQCAPFVYRLRINSTARSNRQDTVRIFLLPRQNEQGRPLSFEDRRLLAIELDSFRVNLRPGMNNIVRQSSNSSVTIPFERTFGNVQSRFCGCGWPAHMLLPKGNANGVEFDLFAMVSRFEDDNANVNAGCDDSYAFCGLRDRVYPSRRAMGFPFDRRASNGVRSVADFVAPYKNMRLATVTLRFMNTIIDR 4yzx A 1.25 BS01 CA A 1 Q37 E39 E84 N107 Q42 E44 E89 N112 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAANAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yzx A 1.25 BS05 ADA A 1 N107 K130 R133 N112 K135 R138 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAANAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yzx A 1.25 BS06 ADA A 2 E39 E84 N107 Q111 R133 N135 G136 E44 E89 N112 Q116 R138 N140 G141 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAANAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4yzx B 1.25 BS08 GTR B 1 N107 K130 R133 K160 N109 K132 R135 K162 4.2.2.2 B9MKT4 26327384 GTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAANAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4z03 A 1.40 BS06 ADA A 2 E39 E84 D107 Q111 R133 N135 G136 E41 E86 D109 Q113 R135 N137 G138 4.2.2.2 B9MKT4 26327384 GTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4z05 A 1.50 BS02 CA A 2 D64 D85 D67 D88 4.2.2.2 B9MKT4 26327384 VGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGADALTVKSEGVVEVIGGSAKEAADKVFQLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4z06 A 1.55 BS02 CA A 2 E84 D85 E89 D90 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFQLNAPCTFKVKNFTATNIGKLVAQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4z06 A 1.55 BS05 ADA A 1 E84 D85 Q111 N113 N135 E89 D90 Q116 N118 N140 4.2.2.2 B9MKT4 26327384 HHVGTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLEKGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVIGGSAKEAADAVFQLNAPCTFKVKNFTATNIGKLVAQNGNTTFKVVIYLEDVTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY 4zbq A 1.92 BS01 DIF A 1 L386 V387 N390 F402 L406 R409 L429 G433 S448 L452 R484 S488 L383 V384 N387 F399 L403 R406 L426 G430 S445 L449 R481 S485 F7BAY6 26652101 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKAGCLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYATVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA 4zbq A 1.92 BS02 DIF A 2 L393 D401 N404 A405 V408 K540 E541 K544 L390 D398 N401 A402 V405 K537 E538 K541 F7BAY6 26652101 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKAGCLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYATVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA 4zbr A 2.19 BS01 DIF A 1 L393 D401 N404 A405 V408 K540 K544 L390 D398 N401 A402 V405 K537 K541 F7BAY6 26652101 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKAGCLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYATVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA 4zbr A 2.19 BS02 NPS A 1 L386 N390 C391 F402 L406 R409 Y410 K413 L429 C437 S448 L452 S488 L383 N387 C388 F399 L403 R406 Y407 K410 L426 C434 S445 L449 S485 F7BAY6 26652101 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKAGCLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYATVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA 4zbr A 2.19 BS03 NPS A 2 R208 A212 D323 L326 L346 A349 K350 S479 L480 A481 R205 A209 D320 L323 L343 A346 K347 S476 L477 A478 F7BAY6 26652101 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKAGCLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYATVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA 4zhn A 1.33 BS01 NUC B 1 T51 Y55 T56 M57 W69 Y76 L118 K127 L128 S129 L130 H131 D135 R161 R210 T37 Y41 T42 M43 W55 Y62 L104 K113 L114 S115 L116 H117 D121 R147 R196 1.14.11.33 P05050 LAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLAFRQAGK 4zi6 A 2.00 BS01 ZN A 1 K258 D263 D281 E342 K246 D251 D269 E330 3.4.11.1,3.4.11.10 O25294 26616008 MLKIKLEKTTFENAKAECSLVFIINKDFSHAWVKNKELLETFKYEGEGVFLDQENKILYAGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCGANALLENLKALFLGLKLGLYEYDTFKSNKKESVLKEAIVALELHKSLEKSAKEALKYAEIMTESLNIVKDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLSVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLNPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKKA 4zi6 A 2.00 BS02 ZN A 2 D263 D340 E342 D251 D328 E330 3.4.11.1,3.4.11.10 O25294 26616008 MLKIKLEKTTFENAKAECSLVFIINKDFSHAWVKNKELLETFKYEGEGVFLDQENKILYAGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCGANALLENLKALFLGLKLGLYEYDTFKSNKKESVLKEAIVALELHKSLEKSAKEALKYAEIMTESLNIVKDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLSVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLNPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKKA 4zi6 A 2.00 BS03 BCT A 1 K258 A341 E342 G343 R344 L368 K246 A329 E330 G331 R332 L356 3.4.11.1,3.4.11.10 O25294 26616008 MLKIKLEKTTFENAKAECSLVFIINKDFSHAWVKNKELLETFKYEGEGVFLDQENKILYAGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCGANALLENLKALFLGLKLGLYEYDTFKSNKKESVLKEAIVALELHKSLEKSAKEALKYAEIMTESLNIVKDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLSVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLNPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKKA 4zi6 A 2.00 BS04 NA A 1 A461 G462 Y465 A449 G450 Y453 3.4.11.1,3.4.11.10 O25294 26616008 MLKIKLEKTTFENAKAECSLVFIINKDFSHAWVKNKELLETFKYEGEGVFLDQENKILYAGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCGANALLENLKALFLGLKLGLYEYDTFKSNKKESVLKEAIVALELHKSLEKSAKEALKYAEIMTESLNIVKDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLSVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLNPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKKA 4zkt A 3.05 BS01 ZN A 1 H212 H216 E251 Y351 H207 H211 E246 Y346 3.4.24.69 26639353 PKINSFNYNDPVNDRTILYIKPEFYKSFNIMKNIWIIPERNVIGTTPQDFHPPTSLKNGDSSYYDPNYLQSDEEKDRFLKIVTKIFNRINNNLSGGILLEELSKANPYLGNDNTPDNQFHIGDASAVEIKFSNGSQHILLPNVIIMGAEPDLFETNSSNISLRNNYMPSNHGFGSIAIVTFSPEYSFRFNDNSINEFIQDPALTLMHELIHSLHGLYGAKGITTTCIITQQQNPLITNRKGINIEEFLTFGGNDLNIITVAQYNDIYTNLLNDYRKIASKLSKVQVSNPQLNPYKDIFQEKYGLDKDASGIYSVNINKFDDILKKLYSFTEFDLATKFQVKCRETYIGQYKYFKLSNLLNDSIYNISEGYNINNLKVNFRGQNANLNPRIIKPITGRGLVKKIIRFCKNIVSVKGIRKSICIEINNGELFFVASENSYNDDNINTPKEIDDNNYENDLDQVILNFNAPGLSDEKLNLTIQNDAYIPKYDSNGTSDIEQHDVNELNVFFYLDAQKVPEGENNVNLTSSIDTALLEQPKIYTFFSSEFINNVNKPVQAALFVSWIQQVLVDFTTEANQKSTVDKIADISIVVPYIGLALNIGNEAQKGNFKDALELLGAGILLEFEPELLIPTILVFTIKSFLGSSDNKNKVIKAINNALKERDEKWKEVYSFIVSNWMTKINTQFNKRKEQMYQALQNQVNAIKTIIESKYNSYTLEEKNELTNKYDIKQIENELNQKVSIAMNNIDRFLTESSISYLMKLINEVKINKLREYDENVKTYLLNYIIQHGSILGESQQELNSMVTDTLNNSIPFKLSSYTDDKILISYFNKFFKRIKSSSVLNMRYKNDKYVDTSGYDSNININGDVYKYPTNKNQFGIYNDKLSEVNISQNDYIIYDNKYKNFSISFWVRIPNYDNKIVNVNNEYTIINCMRDNNSGWKVSLNHNEIIWTLQDNAGINQKLAFNYGNANGISDYINKWIFVTITNDRLGDSKLYINGNLIDQKSILNLGNIHVSDNILFKIVNCSYTRYIGIRYFNIFDKELDETEIQTLYSNEPNTNILKDFWGNYLLYDKEYYLLNVLKPNNFIDRRKDSTLSINNIRSTILLANRLYSGIKVKIQRVNNSSTNDNLVRKNDQVYINFVASKTHLFPLYADTATTNKEKTIKISSSGNRFNQVVVMNSCTMNFKNNNGNNIGLLGFKADTVVASTWYYTHMRDHTNSNGCFWNFISEEHGWQEK 4zkt C 3.05 BS01 ZN C 1 H212 E213 H216 E251 H207 E208 H211 E246 3.4.24.69 26639353 PKINSFNYNDPVNDRTILYIKPEFYKSFNIMKNIWIIPERNVIGTTPQDFHPPTSLKNGDSSYYDPNYLQSDEEKDRFLKIVTKIFNRINNNLSGGILLEELSKANPYLGNDNTPDNQFHIGDASAVEIKFSNGSQHILLPNVIIMGAEPDLFETNSSNISLRNNYMPSNHGFGSIAIVTFSPEYSFRFNDNSINEFIQDPALTLMHELIHSLHGLYGAKGITTTCIITQQQNPLITNRKGINIEEFLTFGGNDLNIITVAQYNDIYTNLLNDYRKIASKLSKVQVSNPQLNPYKDIFQEKYGLDKDASGIYSVNINKFDDILKKLYSFTEFDLATKFQVKCRETYIGQYKYFKLSNLLNDSIYNISEGYNINNLKVNFRGQNANLNPRIIKPITGRGLVKKIIRFCKNIVSVKGIRKSICIEINNGELFFVASENSYNDDNINTPKEIDDNNYENDLDQVILNFNAPGLSDEKLNLTIQNDAYIPKYDSNGTSDIEQHDVNELNVFFYLDAQKVPEGENNVNLTSSIDTALLEQPKIYTFFSSEFINNVNKPVQAALFVSWIQQVLVDFTTEANQKSTVDKIADISIVVPYIGLALNIGNEAQKGNFKDALELLGAGILLEFEPELLIPTILVFTIKSFLGSSDNKNKVIKAINNALKERDEKWKEVYSFIVSNWMTKINTQFNKRKEQMYQALQNQVNAIKTIIESKYNSYTLEEKNELTNKYDIKQIENELNQKVSIAMNNIDRFLTESSISYLMKLINEVKINKLREYDENVKTYLLNYIIQHGSILGESQQELNSMVTDTLNNSIPFKLSSYTDDKILISYFNKFFKRIKSSSVLNMRYKNDKYVDTSGYDSNININGDVYKYPTNKNQFGIYNDKLSEVNISQNDYIIYDNKYKNFSISFWVRIPNYDNKIVNVNNEYTIINCMRDNNSGWKVSLNHNEIIWTLQDNAGINQKLAFNYGNANGISDYINKWIFVTITNDRLGDSKLYINGNLIDQKSILNLGNIHVSDNILFKIVNCSYTRYIGIRYFNIFDKELDETEIQTLYSNEPNTNILKDFWGNYLLYDKEYYLLNVLKPNNFIDRRKDSTLSINNIRSTILLANRLYSGIKVKIQRVNNSSTNDNLVRKNDQVYINFVASKTHLFPLYADTATTNKEKTIKISSSGNRFNQVVVMNSCTMNFKNNNGNNIGLLGFKADTVVASTWYYTHMRDHTNSNGCFWNFISEEHGWQEK 4zkt E 3.05 BS01 ZN E 1 H212 E213 H216 E251 Y351 H207 E208 H211 E246 Y346 3.4.24.69 26639353 PKINSFNYNDPVNDRTILYIKPEFYKSFNIMKNIWIIPERNVIGTTPQDFHPPTSLKNGDSSYYDPNYLQSDEEKDRFLKIVTKIFNRINNNLSGGILLEELSKANPYLGNDNTPDNQFHIGDASAVEIKFSNGSQHILLPNVIIMGAEPDLFETNSSNISLRNNYMPSNHGFGSIAIVTFSPEYSFRFNDNSINEFIQDPALTLMHELIHSLHGLYGAKGITTTCIITQQQNPLITNRKGINIEEFLTFGGNDLNIITVAQYNDIYTNLLNDYRKIASKLSKVQVSNPQLNPYKDIFQEKYGLDKDASGIYSVNINKFDDILKKLYSFTEFDLATKFQVKCRETYIGQYKYFKLSNLLNDSIYNISEGYNINNLKVNFRGQNANLNPRIIKPITGRGLVKKIIRFCKNIVSVKGIRKSICIEINNGELFFVASENSYNDDNINTPKEIDDNNYENDLDQVILNFNAPGLSDEKLNLTIQNDAYIPKYDSNGTSDIEQHDVNELNVFFYLDAQKVPEGENNVNLTSSIDTALLEQPKIYTFFSSEFINNVNKPVQAALFVSWIQQVLVDFTTEANQKSTVDKIADISIVVPYIGLALNIGNEAQKGNFKDALELLGAGILLEFEPELLIPTILVFTIKSFLGSSDNKNKVIKAINNALKERDEKWKEVYSFIVSNWMTKINTQFNKRKEQMYQALQNQVNAIKTIIESKYNSYTLEEKNELTNKYDIKQIENELNQKVSIAMNNIDRFLTESSISYLMKLINEVKINKLREYDENVKTYLLNYIIQHGSILGESQQELNSMVTDTLNNSIPFKLSSYTDDKILISYFNKFFKRIKSSSVLNMRYKNDKYVDTSGYDSNININGDVYKYPTNKNQFGIYNDKLSEVNISQNDYIIYDNKYKNFSISFWVRIPNYDNKIVNVNNEYTIINCMRDNNSGWKVSLNHNEIIWTLQDNAGINQKLAFNYGNANGISDYINKWIFVTITNDRLGDSKLYINGNLIDQKSILNLGNIHVSDNILFKIVNCSYTRYIGIRYFNIFDKELDETEIQTLYSNEPNTNILKDFWGNYLLYDKEYYLLNVLKPNNFIDRRKDSTLSINNIRSTILLANRLYSGIKVKIQRVNNSSTNDNLVRKNDQVYINFVASKTHLFPLYADTATTNKEKTIKISSSGNRFNQVVVMNSCTMNFKNNNGNNIGLLGFKADTVVASTWYYTHMRDHTNSNGCFWNFISEEHGWQEK 4zla A 1.90 BS05 BES A 1 K258 D263 K270 D281 D340 E342 T367 L368 T369 G370 I428 A461 K247 D252 K259 D270 D329 E331 T356 L357 T358 G359 I417 A450 3.4.11.1,3.4.11.10 O25294 26616008 MLKIKLEKTTFENAKAECSLVFIINKDFSHAWVKNKELLETFKYEGEGVFLDQENKILYAGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCGAHNALLENLKALFLGLKLGLYEYDTFKSNKKESVLKEAIVALELHKSLEKSAKEALKYAEIMTESLNIVKDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLSVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLNPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKKA 4zla C 1.90 BS05 BES C 1 K258 D263 K270 M278 D281 N338 D340 E342 T367 L368 T369 G370 I428 A461 K246 D251 K258 M266 D269 N326 D328 E330 T355 L356 T357 G358 I416 A449 3.4.11.1,3.4.11.10 O25294 26616008 MLKIKLEKTTFENAKAECSLVFIINKDFSHAWVKNKELLETFKYEGEGVFLDQENKILYAGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCGANALLENLKALFLGLKLGLYEYDTFKSNKKESVLKEAIVALELHKSLEKSAKEALKYAEIMTESLNIVKDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLSVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLNPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKKA 4zla E 1.90 BS05 BES E 1 K258 D263 K270 M278 D281 D340 E342 R344 T367 L368 T369 G370 I428 K246 D251 K258 M266 D269 D328 E330 R332 T355 L356 T357 G358 I416 3.4.11.1,3.4.11.10 O25294 26616008 MLKIKLEKTTFENAKAECSLVFIINKDFSHAWVKNKELLETFKYEGEGVFLDQENKILYAGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCGAALLENLKALFLGLKLGLYEYDTFKSNKKESVLKEAIVALELHKPSLEKSAKEALKYAEIMTESLNIVKDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLSVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLNPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKKA 5acp A 1.98 BS03 MG A 1 S139 L141 Y191 D199 I201 S97 L99 Y132 D140 I142 26643332 GHKPLEVIKIEDGVYLHTSFKNIEGYGLVDSNGLVVLDNNQAYIIDTPWSEEDTKLLLSWATDRGYQVMASISTHSHEDRTAGIKLLNSKSIPTYTSELTKKLLAREGKPVPTHYFKDDEFTLGNGLIELYYPGAGHTEDNIVAWLPKSKILFGGCLVRSHEREGLGYVGDASISSWADSIKNIVSKKYPIQMVVPGHGKVGSSDILDHTIDLAESASN 5acq A 1.70 BS02 ZN A 2 H116 H118 H196 C221 H74 H76 H136 C155 26643332 HKPLEVIKIEDGVYLHTSFKNIEGYGLVDSNGLVVLDNNQAYIIDTPWSEEDTKLLLSWATDRGYQVMASISTHSHEDRTAGIKLLNSKSIPTYTSELTKKLLAREGKPVPTHYFKDDEFTLGNGLIELYYPGAGHTEDNIVAWLPKSKILFGGCLVRSHEAEGLGYVGDASISSWADSIKNIVSKKYPIQMVVPGHGKVGSSDILDHTIDLAESASN 5acr A 1.90 BS02 CA A 1 S112 I113 S114 I125 T136 Y137 S69 I70 S71 I82 T92 Y93 26643332 KPLEVIKIEDGVYLHTSFKNIEGYGLVDSNGLVVLDNNQAYIIDTPWSEEDTKLLLSWATDRGYQVMASISTHSHEDRTAGIKLLNSKSIPTYTSELTKKLLAREGKPVPTHYFKDDEFTLGNGLIELYYPGAGHTEDNIVAWLPKSKILFGGCLVRSHEYEGLGYVGDASISSWADSIKNIVSKKYPIQMVVPGHGKVGSSDILDHTIDLAESASN 5av5 A 2.40 BS01 NUC I 1 K37 Y41 R42 P43 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 M120 K1 Y5 R6 P7 T9 R27 R36 R47 F48 Q49 S50 R80 V81 T82 M84 P68431 26607036 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 5av5 B 2.40 BS01 NUC I 1 R23 T30 P32 R36 K77 R3 T10 P12 R16 K57 P62805 26607036 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 5av5 B 2.40 BS02 NUC J 1 V21 R45 I46 S47 G48 R78 K79 T80 V1 R25 I26 S27 G28 R58 K59 T60 P62805 26607036 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 5av5 D 2.40 BS01 NUC I 1 R29 K30 S32 R33 K34 S55 S56 R86 S87 T88 K125 R1 K2 S4 R5 K6 S27 S28 R58 S59 T60 K97 P06899 26607036 RKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 5av5 D 2.40 BS02 NUC J 1 R29 R31 S32 R33 K34 E35 S36 I39 Y40 R1 R3 S4 R5 K6 E7 S8 I11 Y12 P06899 26607036 RKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 5av5 H 2.40 BS02 NUC J 1 R31 S32 Y42 S55 S56 R86 S87 T88 R1 S2 Y12 S25 S26 R56 S57 T58 P06899 26607036 RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5av6 C 2.20 BS01 NUC I 1 A14 K15 T16 R17 R29 R32 R42 R77 A2 K3 T4 R5 R17 R20 R30 R65 P04908 26607036 KAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 5av6 D 2.20 BS01 NUC I 1 R29 K30 S32 R33 S55 S56 R86 S87 T88 R1 K2 S4 R5 S27 S28 R58 S59 T60 P06899 26607036 RKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 5av6 H 2.20 BS02 NUC J 1 R31 S32 S55 S56 R86 S87 T88 R1 S2 S25 S26 R56 S57 T58 P06899 26607036 RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5av8 A 2.20 BS01 NUC I 1 K37 R40 Y41 R42 P43 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 M120 K1 R4 Y5 R6 P7 T9 R27 R36 R47 F48 Q49 S50 R80 V81 T82 M84 P68431 26607036 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 5av8 D 2.20 BS01 NUC I 1 R29 K30 R31 S32 R33 S55 S56 R86 S87 T88 R1 K2 R3 S4 R5 S27 S28 R58 S59 T60 P06899 26607036 RKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 5avb B 2.40 BS02 NUC J 1 V21 R45 I46 G48 R78 K79 T80 V1 R25 I26 G28 R58 K59 T60 P62805 26607036 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 5avc H 2.40 BS02 NUC J 1 R31 S32 R33 Y42 S55 S56 R86 S87 T88 R1 S2 R3 Y12 S25 S26 R56 S57 T58 P06899 26607036 RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5br4 A 0.91 BS02 NAD A 1 D39 T41 L42 P70 G97 G98 S99 P100 D102 T140 T141 T144 A146 T149 N151 V153 K162 M181 G184 C185 L189 H277 D39 T41 L42 P70 G97 G98 S99 P100 D102 T140 T141 T144 A146 T149 N151 V153 K162 M181 G184 C185 L189 H277 1.1.1.77 P0A9S2 26512129 MMANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQCGVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLGVFQNSGADYLIAIGGGSPQDTCKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKRRKFVCVDPHDIPQVAFIDADMMDGCPPALKAATGVDALTHAIEGYITRGAWALTDALHIKAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPHGVANAILLPHVMRYNADFTGEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVGIPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAWLE 5bun A 2.98 BS01 BOG A 1 T365 V367 D368 D371 T365 V367 D368 D371 26563565 ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAENRNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSTQYDDSNMGQNKIGLNFSLPLYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYDAKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPESV 5bun A 2.98 BS02 BOG A 2 Q241 H244 Q303 Q241 H244 Q303 26563565 ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAENRNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSTQYDDSNMGQNKIGLNFSLPLYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYDAKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPESV 5bun C 2.98 BS01 BOG A 1 V367 D368 D371 V367 D368 D371 26563565 ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAENRNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSTQYDDSNMGQNKIGLNFSLPLYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYDAKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPESVAPETPD 5bx0 A 2.93 BS01 4W5 A 1 L74 N78 V82 A95 E144 H145 M146 N195 L197 D208 L36 N40 V44 A57 E106 H107 M108 N157 L159 D170 2.7.12.2 Q02750 26637553 ELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLN 5cbx B 2.00 BS01 NUC C 1 G439 S440 F444 R447 Y455 R470 K471 R477 G23 S24 F28 R31 Y39 R54 K55 R61 PPKICLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLQAGMNLEA 5cbx B 2.00 BS02 NUC D 1 G430 C431 H432 Y433 K442 K446 R447 G14 C15 H16 Y17 K26 K30 R31 PPKICLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLQAGMNLEA 5cbx E 2.00 BS02 NUC H 1 G439 S440 R447 R470 K471 R477 G23 S24 R31 R54 K55 R61 PPKICLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLQAGMNLE 5cbx F 2.00 BS01 NUC G 1 G439 S440 V443 R447 Y455 R470 K471 P474 R477 G23 S24 V27 R31 Y39 R54 K55 P58 R61 PPKICLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLQAGMNLEA 5cby A 2.00 BS02 NUC D 1 G439 S440 F444 R447 R470 K471 P474 R477 G23 S24 F28 R31 R54 K55 P58 R61 PPKICLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLQAGMNLEARK 5cbz B 2.20 BS01 NUC C 1 G439 S440 R447 Y455 R470 K471 R477 G22 S23 R30 Y38 R53 K54 R60 SKVCLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLRKCLQAGMNLGAR 5cc0 A 2.41 BS02 NUC D 1 G439 S440 V443 F444 R447 Y455 R470 K471 R477 G22 S23 V26 F27 R30 Y38 R53 K54 R60 QKVCLICGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLRKCLQAGMTLGA 5cc0 B 2.41 BS01 NUC C 1 S440 R447 R470 K471 R477 S23 R30 R53 K54 R60 QKVCLICGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLRKCLQAGMTLG 5cc1 B 2.30 BS01 NUC C 1 S440 R447 R470 R477 S23 R30 R53 R60 P04150 PKLCLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEA 5cc1 W 2.30 BS01 NUC Y 1 S440 F444 R447 R470 K471 R477 S24 F28 R31 R54 K55 R61 P04150 PPKLCLVCGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEAR 5cet A 2.00 BS01 MN A 1 D47 D106 H131 T151 D181 D33 D92 H117 T137 D167 3.1.-.-,3.1.3.7 P71615 RRAGARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALGLTRAPP 5cet A 2.00 BS02 MN A 2 H41 D45 D106 H27 D31 D92 3.1.-.-,3.1.3.7 P71615 RRAGARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALGLTRAPP 5ceu A 2.36 BS01 NUC C 1 D45 D106 R112 H132 T180 D181 W187 E263 S292 R294 G309 G310 H312 A315 G317 Y318 D29 D90 R96 H116 T164 D165 W171 E247 S276 R278 G293 G294 H296 A299 G301 Y302 3.1.-.-,3.1.3.7 P71615 AGARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALGLTRAPP 5ceu A 2.36 BS02 MN A 1 D47 D106 H131 D181 D31 D90 H115 D165 3.1.-.-,3.1.3.7 P71615 AGARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALGLTRAPP 5ceu B 2.36 BS01 NUC D 1 H41 D45 D106 R112 H131 H132 T180 D181 W187 S292 R294 G309 G310 G311 H312 A315 A316 G317 Y318 H25 D29 D90 R96 H115 H116 T164 D165 W171 S276 R278 G293 G294 G295 H296 A299 A300 G301 Y302 3.1.-.-,3.1.3.7 P71615 AGARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALGLTRAPP 5ceu B 2.36 BS02 MN B 1 D47 D106 H131 H132 T151 D181 D31 D90 H115 H116 T135 D165 3.1.-.-,3.1.3.7 P71615 AGARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALGLTRAPP 5cey D 2.39 BS01 PE7 D 1 R66 V68 S70 K81 N82A R65 V67 S69 K80 N82 VQLQESGPGLVKPSETLSVTCIVSGGSISNYYWTWIRQSPGKGLEWIGYISDRETTTYNPSLKSRVVISRDTSKNQLSLKLNSVTAADTAIYYCATARRGQRIYGVVSFGEFFYYYYMDVWGKGTAVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 5cqz A 2.90 BS02 53O A 1 S40 L476 R478 S15 L449 R451 3.1.3.5 P49902 KYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHT 5cqz A 2.90 BS03 53O B 1 Q420 S445 R446 Q393 S418 R419 3.1.3.5 P49902 KYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHT 5cqz B 2.90 BS03 MG B 2 R39 Y457 R14 Y418 3.1.3.5 P49902 KYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEH 5cqz B 2.90 BS04 53O B 1 R39 S40 R478 R14 S15 R439 3.1.3.5 P49902 KYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEH 5ddo G 3.10 BS01 NUC A 1 Y13 N15 N16 E19 K22 L44 S48 L49 K50 M51 R52 G53 Q54 F56 K80 Q85 T89 D90 Y7 N9 N10 E13 K16 L38 S42 L43 K44 M45 R46 G47 Q48 F50 K74 Q79 T83 D84 P09012 26655897 RPNHTIYINNLNEKIKKDELKKSLHAIFSRFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSD 5ddo C 3.10 BS01 NUC B 1 Y13 N15 N16 K22 D24 L49 K50 M51 R52 Q54 F56 K80 R83 Y86 A87 K88 T89 S91 Y8 N10 N11 K17 D19 L44 K45 M46 R47 Q49 F51 K75 R78 Y81 A82 K83 T84 S86 P09012 26655897 TRPNHTIYINNLNEKIKKDELKKSLHAIFSRFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSD 5ddp C 2.30 BS01 NUC B 1 E4 Y12 N14 N15 E18 K21 K22 S45 R46 S47 L48 K49 M50 R51 G52 Q53 F55 K79 Q84 Y85 A86 K87 T88 D89 S90 D91 E2 Y10 N12 N13 E16 K19 K20 S43 R44 S45 L46 K47 M48 R49 G50 Q51 F53 K77 Q82 Y83 A84 K85 T86 D87 S88 D89 P09012 26655897 PETRPNHTIYINNLNEKIKKDELKKSLHAIFSRFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAK 5ddr C 2.61 BS01 NUC B 1 Y12 N14 N15 E18 K21 L43 S45 R46 S47 L48 K49 M50 R51 Q53 F55 K79 Q84 Y85 A86 K87 T88 S90 D91 Y11 N13 N14 E17 K20 L42 S44 R45 S46 L47 K48 M49 R50 Q52 F54 K78 Q83 Y84 A85 K86 T87 S89 D90 P09012 26655897 VPETRPNHTIYINNLNEKIKKDELKKSLHAIFSRFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAK 5dqf A 2.15 BS01 LCR A 1 K17 K20 L24 D131 L134 G135 L138 L154 A157 K14 K17 L21 D128 L131 G132 L135 L151 A154 P35747 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA 5dqf A 2.15 BS02 CZE A 1 R208 A212 L326 G327 L330 L346 K350 E353 R205 A209 L323 G324 L327 L343 K347 E350 P35747 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA 5e4r A 1.94 BS01 NAP A 1 G24 Y25 G26 S27 Q28 L47 E48 S53 L80 V81 P82 D83 V85 Q86 A107 H108 S132 P133 G134 A397 V398 S399 G23 Y24 G25 S26 Q27 L46 E47 S52 L79 V80 P81 D82 V84 Q85 A106 H107 S131 P132 G133 A387 V388 S389 1.1.1.86 E0SRA9 AKIYKDEDISLEPIKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIADIIVFLVPDMVQKSLWLNSVKDFMKKGADLVFAHGFNIHFKIIEPPKDSDVYMIAPKSPGPIVRRSYEMGGGVPALVAVYQNVSGEALQKALAIAKGIGCARAGVIESTFKEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKMKIVLERIRSGEFAREWIKEYERGMPTVFKELSELEGSTIETVGRKLREMMFRGMLFGEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKMKIVLERIRSGEFAREWIKEYERGMPTVFKELSELEGSTIETVGRKLREMMFRGM 5e4r A 1.94 BS02 MG A 1 D191 E195 D190 E194 1.1.1.86 E0SRA9 AKIYKDEDISLEPIKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIADIIVFLVPDMVQKSLWLNSVKDFMKKGADLVFAHGFNIHFKIIEPPKDSDVYMIAPKSPGPIVRRSYEMGGGVPALVAVYQNVSGEALQKALAIAKGIGCARAGVIESTFKEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKMKIVLERIRSGEFAREWIKEYERGMPTVFKELSELEGSTIETVGRKLREMMFRGMLFGEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKMKIVLERIRSGEFAREWIKEYERGMPTVFKELSELEGSTIETVGRKLREMMFRGM 5e4r A 1.94 BS03 40E A 1 P133 D191 E195 L199 V200 E378 I382 V398 S399 A402 P132 D190 E194 L198 V199 E368 I372 V388 S389 A392 1.1.1.86 E0SRA9 AKIYKDEDISLEPIKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIADIIVFLVPDMVQKSLWLNSVKDFMKKGADLVFAHGFNIHFKIIEPPKDSDVYMIAPKSPGPIVRRSYEMGGGVPALVAVYQNVSGEALQKALAIAKGIGCARAGVIESTFKEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKMKIVLERIRSGEFAREWIKEYERGMPTVFKELSELEGSTIETVGRKLREMMFRGMLFGEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKMKIVLERIRSGEFAREWIKEYERGMPTVFKELSELEGSTIETVGRKLREMMFRGM 5e9n A 0.95 BS01 CU A 1 H112 H402 H452 H112 H402 H452 1.10.3.2 I1VE66 AQIGPVTDLHITNANISPDGFSRPAVLAGGTFPGPTIAGNTGDNFQITVFNDLTDPSMLTDTSIHWHGLFQKGTNWADGPAFVTQCPIITGQSFDYNFNVPGQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPNASLYDVDDDTTIITLADWYHTLAQQEPIGAAITADATLINGLGRSFTNTTASPLSVITVQSGKRYRMRLVSISCDPNYLFSIDGHDMTIIEVDGVNSQQLTVDQIQIFAAQRYSFVLNANQPVGNYWIRAQPNSGGQGFDGGINSAILRYEGATVEDPTTTAPTTFSNPLVETDLHPLADLGVPGQPFRGGADDPLVLNLAFANGRFSIDGVSFVPPTVPVLLQILSGAQNAQDLLPAGSVISLPSNSVIEVALPAGAAGGPHPFHLHGHNFAVVQSANNATPNYVNPIWRDTVSIGGTGDNVTIRFTTNNPGPWFLHCHIDWHLEAGFAIVFAEDIPDTASANPVPQAWSDLCPAYDQAH 5e9n A 0.95 BS04 CU A 4 H397 C453 I455 H458 H397 C453 I455 H458 1.10.3.2 I1VE66 AQIGPVTDLHITNANISPDGFSRPAVLAGGTFPGPTIAGNTGDNFQITVFNDLTDPSMLTDTSIHWHGLFQKGTNWADGPAFVTQCPIITGQSFDYNFNVPGQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPNASLYDVDDDTTIITLADWYHTLAQQEPIGAAITADATLINGLGRSFTNTTASPLSVITVQSGKRYRMRLVSISCDPNYLFSIDGHDMTIIEVDGVNSQQLTVDQIQIFAAQRYSFVLNANQPVGNYWIRAQPNSGGQGFDGGINSAILRYEGATVEDPTTTAPTTFSNPLVETDLHPLADLGVPGQPFRGGADDPLVLNLAFANGRFSIDGVSFVPPTVPVLLQILSGAQNAQDLLPAGSVISLPSNSVIEVALPAGAAGGPHPFHLHGHNFAVVQSANNATPNYVNPIWRDTVSIGGTGDNVTIRFTTNNPGPWFLHCHIDWHLEAGFAIVFAEDIPDTASANPVPQAWSDLCPAYDQAH 5ek0 A 3.53 BS01 5P2 A 1 E1534 Y1537 W1538 N1540 V1541 G1581 M1582 F1583 A1585 D1586 E1589 F1598 R1602 A1604 R1605 R1608 E47 Y50 W51 N53 V54 G94 M95 F96 A98 D99 E102 F111 R115 A117 R118 R121 A8EVM5 PRGSHMYLRITNIVESSFFTKFIIYLIVLNMVTMMVEKEGQSQHMTEVLYWINVVFIILFTIEIILRIYVHRISFFKDPWSLFDFVVVIISIVGMFLADLIETYFVSPTLFRVIRLARIGRILRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAIIVDAMAILNQKEEQHIID 5ek2 A 2.68 BS01 HEM A 1 F163 S167 V170 F214 I217 F226 S263 A264 F270 F291 R343 H346 I349 V350 Y353 L384 F387 L388 V391 F152 S156 V159 F203 I206 F215 S252 A253 F259 F280 R332 H335 I338 V339 Y342 L355 F358 L359 V362 1.13.11.52 P14902 26642377 SKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQGGTDLMNFLKTVRSTTEKSLLKEG 5ek2 A 2.68 BS02 5PJ A 1 Y126 C129 V130 F163 F164 R231 G262 S263 A264 I354 L384 Y115 C118 V119 F152 F153 R220 G251 S252 A253 I343 L355 1.13.11.52 P14902 26642377 SKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQGGTDLMNFLKTVRSTTEKSLLKEG 5ek2 B 2.68 BS01 HEM B 1 F163 S167 V170 F214 I217 F226 S263 A264 F270 F291 R343 H346 I349 V350 Y353 I354 L384 L388 V391 F152 S156 V159 F203 I206 F215 S252 A253 F259 F280 R332 H335 I338 V339 Y342 I343 L359 L363 V366 1.13.11.52 P14902 26642377 SKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQEAKGTGGTDLMNFLKTVRSTTEKSLLKEG 5ek2 B 2.68 BS02 5PJ B 1 C129 V130 F163 F164 S167 R231 L234 G262 S263 A264 C118 V119 F152 F153 S156 R220 L223 G251 S252 A253 1.13.11.52 P14902 26642377 SKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQEAKGTGGTDLMNFLKTVRSTTEKSLLKEG 5ek3 A 2.21 BS01 HEM A 1 Y126 F163 S167 V170 F214 I217 F226 S263 A264 G265 F270 F291 R343 H346 I349 V350 Y353 I354 F387 L388 V391 Y115 F152 S156 V159 F203 I206 F215 S252 A253 G254 F259 F280 R332 H335 I338 V339 Y342 I343 F358 L359 V362 1.13.11.52 P14902 26642377 SKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQGGTDLMNFLKTVRSTTEKSLLKEG 5ek3 A 2.21 BS02 5PK A 1 C129 V130 F163 F164 R231 L234 G262 A264 I354 C118 V119 F152 F153 R220 L223 G251 A253 I343 1.13.11.52 P14902 26642377 SKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQGGTDLMNFLKTVRSTTEKSLLKEG 5ek3 B 2.21 BS02 5PK B 1 Y126 C129 V130 F163 F164 R231 L234 G262 S263 A264 L384 Y114 C117 V118 F151 F152 R219 L222 G250 S251 A252 L359 1.13.11.52 P14902 26642377 KEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG 5ek4 A 2.64 BS02 5PF A 1 C129 V130 F163 F164 R231 L234 G262 S263 A264 I354 C118 V119 F152 F153 R220 L223 G251 S252 A253 I343 1.13.11.52 P14902 26642377 SKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQGGTDLMNFLKTVRSTTEKSLLK 5ek4 B 2.64 BS02 5PF B 1 Y126 C129 V130 F163 F164 F226 R231 L234 G262 A264 I354 Y116 C119 V120 F153 F154 F216 R221 L224 G252 A254 I344 1.13.11.52 P14902 26642377 ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQGGTDLMNFLKTVRSTTEKSLLKEG 5ek8 A 2.70 BS01 FE2 A 1 H359 H364 H570 N574 I668 H359 H364 H570 N574 I668 B7K2Q5 MSTKTKTIFDEIKAALVLKVIDSPLGRKLIEEKAEKQVSKTQEAITKPIEQLNKATGQLLFSDTNKPLHNIELEVWDRDVGTPSDYLGKGVTDQNGRFEIYYDPEKAGFKDAPDLELRVIDNRVTFDSDNQPVYTNRIAYIIKGGDNVTQKTYDFGTLTVPYWPYDPNSPFARIFMPNPEETPDDYSVGRKFQAYASANVLTPIKAKHTIANTLNPKEPSLTQIQADYPPNLTINLDREKPGYTRSDEYFVLRVLNGMNPCLLKRSKSDPNQFKMSFIWDNYEKDTEHDLHNVEAYFVLKDGKLFPTMITIQSRYPDSLAPHSPLKDREVYTPNDGEKWLQAKRIFRTAALFDGEAIEHYAKAHVQMEQYAVACFRNLRKNPIRLMLTPHLKSIININRRGDDLLVEPNLGLFVTNGPLTYPGFLQMCTEVVATYDWKDWQPRQPICDDHKYAKAANLYWQILTEYVDAFFAKHQQAIADEWVEIRRFSEDLVEHSMPYQPIEGIMANTDSDYEWYDTGELDKPDLPRATFNGKTKVIRPITNSNQPSATDIDNLKQCCRHIIFHTTLWHTWVNDSQSDEGGELAYNSLALRNGSFGSETDPNIAPDPIEATNQVYIFSVLNGIKYGLLVKNEDDDVPEELRTALLNRKDQFAELGIDIGNIRTLINI 5epk A 1.80 BS01 III B 1 E9 Q10 V11 F12 A13 A14 W33 W36 E44 N48 L50 D51 R53 L54 E1 Q2 V3 F4 A5 A6 W25 W28 E36 N40 L42 D43 R45 L46 Q14781 EQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKE 5epl A 1.81 BS01 III C 1 H9 V10 F11 A12 V13 W32 W35 E43 N47 L49 D50 R52 L53 H4 V5 F6 A7 V8 W27 W30 E38 N42 L44 D45 R47 L48 6.3.2.- O00257 GSEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQN 5eq0 A 1.18 BS01 III B 1 E8 R9 V10 F11 A12 A13 W32 W35 T41 E43 N47 L49 D50 R52 L53 E2 R3 V4 F5 A6 A7 W26 W29 T35 E37 N41 L43 D44 R46 L47 Q9HC52 GERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEERE 5eyg B 2.20 BS03 CA B 2 E70 D88 I90 E70 D88 I90 3.1.3.25 A0A0D6HL44 MTDKTLQQIDKLICSWLKQIDNVIPQLIMEMTTETKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNEINHLWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGFKMEEPPSLKLEDAIISFNAQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNANGGYQKYR 5eyg B 2.20 BS04 NAP B 1 D88 D91 G92 T93 A94 N160 V163 G183 C185 N202 T203 N204 D209 D88 D91 G92 T93 A94 N160 V163 G183 C185 N202 T203 N204 D209 3.1.3.25 A0A0D6HL44 MTDKTLQQIDKLICSWLKQIDNVIPQLIMEMTTETKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNEINHLWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGFKMEEPPSLKLEDAIISFNAQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNANGGYQKYR 5eyh A 2.50 BS04 NAP A 1 H38 F40 E70 D88 I90 D91 G92 T93 N160 V163 G183 A184 C185 N202 T203 N204 D209 H37 F39 E69 D87 I89 D90 G91 T92 N159 V162 G182 A183 C184 N201 T202 N203 D208 3.1.3.25 A0A0D6HL44 TDKTLQQIDKLICSWLKQIDNVIPQLIMEMTTETKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNEINHLWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGFKMEEPPSLKLEDAIISFNAQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNANGGYQK 5f1q A 1.96 BS01 GLN A 1 T48 G50 Y142 W433 T434 D436 L524 G525 T20 G22 Y114 W405 T406 D408 L496 G497 A0A0H2YM47 KTLVYCSEGSPEGFNPQLFTSGTTYDASSVPIYNRLVEFKIGTTEIEPSLAERWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIYSFMRQKDDKNPYHKVSGGSYEYFQGMGMGDLITNVVKVDDNTVRFELTRPESPFLADLAMDFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGTKPKIDRLVFSITPDASVRYAKLQKNECQIMPYPNPADIARMKEDKTINLMEQPGLNVGYLSFNIEKKPLDNLKVRQALTMAVNKDAIIDAVYQGAGQAAKNLIPPTMWGYNDDVKDYAYDPAKAKELLKEAGLPDGFSIDLWAMPVQRPYNPNARRMAEMIQSDWAKIGVKAKIVTYEWGEYLKRAKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQPARAEADHDKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLDAGENLY 5f1q A 1.96 BS02 GLN A 2 T48 S49 G50 R383 Y385 W414 L418 M431 G432 W433 S457 Y459 T20 S21 G22 R355 Y357 W386 L390 M403 G404 W405 S429 Y431 A0A0H2YM47 KTLVYCSEGSPEGFNPQLFTSGTTYDASSVPIYNRLVEFKIGTTEIEPSLAERWEVSEDGKTYTFYLRKGVKWQDNKDFKPTRDFNADDVIYSFMRQKDDKNPYHKVSGGSYEYFQGMGMGDLITNVVKVDDNTVRFELTRPESPFLADLAMDFASILSAEYADNMLKAGTPEKVDLNPIGTGPFQLQQYQKDSRILYKAFPGFWGTKPKIDRLVFSITPDASVRYAKLQKNECQIMPYPNPADIARMKEDKTINLMEQPGLNVGYLSFNIEKKPLDNLKVRQALTMAVNKDAIIDAVYQGAGQAAKNLIPPTMWGYNDDVKDYAYDPAKAKELLKEAGLPDGFSIDLWAMPVQRPYNPNARRMAEMIQSDWAKIGVKAKIVTYEWGEYLKRAKDGEHETVMMGWTGDNGDPDNFFATLFSCDAAKQGSNYSKWCYKPFEDLIQPARAEADHDKRVALYKQAQVVMNEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLDAGENLY 5f23 A 1.50 BS01 NAD A 1 F139 N143 R147 F177 F178 T179 K180 H267 K268 F144 N148 R152 F182 F183 T184 K185 H255 K256 6.3.1.5 Q9HUP3 HHHHHMQQIQRDIAQALQVQPPFQSEADVQAQIARRIAFIQQCLKDSGLKTLVLGISGGVDSLTAGLLAQRAVEQLREQTGDQAYRFIAVRLPYQVQQDEADAQASLATIRADEEQTVNIGPSVKALAEQLEALEGLEPAKSDFVIGNIKARIRMVAQYAIAGARGGLVIGTDHAAEAVMGFFTKFGDGACDLAPLSGLAKHQVRALARALGAPENLVEKIHGVTYAEIDAFLHGQPLREEAARVIVDTYHKTQHKRELPKAP 5f24 A 2.50 BS03 IPD A 1 E70 D88 I90 D91 G92 T93 G183 A184 C185 N202 E68 D83 I85 D86 G87 T88 G178 A179 C180 N197 3.1.3.25 A0A0D6HL44 TDKTLQQIDKLICSWLKQIDNVIPQLIMEMTETKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKMITNEINHLWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGFKMEEPPSLKLEDAIISFNAQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNANGGYQKYR 5f24 B 2.50 BS03 IPD B 1 D88 I90 D91 G92 T93 G183 A184 C185 N202 D209 D79 I81 D82 G83 T84 G174 A175 C176 N193 D200 3.1.3.25 A0A0D6HL44 KTLQQIDKLICSWLKQIDNVIPQLIMEMTTEDLVTNVDKQIQQQFQQFLATYFPEHQLLAEEKSNAMITNEINHLWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGFKMEEPPSLKLEDAIISFNAQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNANGGYQKY 5f3m A 1.50 BS01 NEU A 1 V17 F18 E21 L71 V72 E73 K99 P103 V17 F18 E21 L71 V72 E73 K99 P103 4.1.2.25 Q81VW7 MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKRAGESDDLEHSVNYGELFELCRKVVEDRTYKLVESIAENIATDILKQYESISRCTIKVIKPDPPIPGHYRAVAVEITRERP 5f6r A 1.18 BS01 5VO A 1 H71 P79 G80 F114 T115 G116 Q117 H74 P82 G83 F117 T118 G119 Q120 4.2.1.59 A0A0B6NZG1 SNAMVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKVTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATDLKVGLFKDTN 5f6r A 1.18 BS02 5VO B 1 R105 A106 L107 R108 A109 L110 4.2.1.59 A0A0B6NZG1 SNAMVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKVTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATDLKVGLFKDTN 5f6r B 1.18 BS02 5VO B 1 H71 P79 G80 F114 T115 G116 Q117 Y156 H74 P82 G83 F117 T118 G119 Q120 Y159 4.2.1.59 A0A0B6NZG1 SNAMVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKVTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATDLKVGLFKDT 5f8u B 3.35 BS01 P32 B 1 W117 T118 D121 V122 F201 S211 W303 F306 F307 N310 N329 W79 T80 D83 V84 F163 S173 W220 F223 F224 N227 N246 P07700 26643842 QWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYCRSPDFRKAFKRLLAF 5fc0 C 2.97 BS01 NUC P 1 G2 K3 I4 S5 T6 S31 Y41 Q42 R49 G1 K2 I3 S4 T5 S30 Y40 Q41 R48 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 5fc0 C 2.97 BS02 NUC N 1 Y9 P14 P40 Q42 T43 N47 E64 Y8 P13 P39 Q41 T42 N46 E63 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 5fc0 D 2.97 BS01 NUC P 1 G2 K3 I4 K8 Y9 P14 R15 P40 Q42 T43 Q46 N47 G1 K2 I3 K7 Y8 P13 R14 P39 Q41 T42 Q45 N46 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 5fc0 D 2.97 BS02 NUC N 1 G2 K3 S5 K29 A30 Y41 Q42 I45 R49 Y68 G1 K2 S4 K28 A29 Y40 Q41 I44 R48 Y67 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 5fc0 A 2.97 BS01 NUC P 1 A30 S31 Y41 Q42 R49 I66 Y68 A25 S26 Y36 Q37 R44 I61 Y63 O93706 26339031 TDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 5fc0 B 2.97 BS01 NUC P 1 G2 K3 Y9 P14 P40 Q42 T43 G1 K2 Y8 P13 P39 Q41 T42 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 5fc0 B 2.97 BS02 NUC N 1 G2 K3 S5 K29 A30 S31 Y41 Q42 R49 E65 I66 Y68 G1 K2 S4 K28 A29 S30 Y40 Q41 R48 E64 I65 Y67 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 5fc0 E 2.97 BS01 NUC P 1 Y9 P14 P40 Q42 T43 N47 Y8 P13 P39 Q41 T42 N46 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 5fc0 F 2.97 BS01 NUC P 1 G2 K3 I4 S5 K29 A30 Y41 Q42 I45 Y68 G1 K2 I3 S4 K28 A29 Y40 Q41 I44 Y67 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 5flx B 3.90 BS01 NUC z 1 K144 N147 K195 S203 K123 N126 K174 S182 P61247 26604301 VDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHG 5flx F 3.90 BS01 NUC z 1 I128 R130 G132 T133 V134 S184 N186 K191 I114 R116 G118 T119 V120 S170 N172 K177 P46782 26604301 PDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR 5flx O 3.90 BS01 NUC z 1 V62 D67 S70 P71 Y72 L151 V47 D52 S55 P56 Y57 L136 P62263 26604301 SLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL 5flx X 3.90 BS01 MG X 1 H110 A111 H109 A110 P62266 26604301 GKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKER 5flx Z 3.90 BS01 NUC z 1 Y65 E75 R76 K78 Y25 E35 R36 K38 P62851 26604301 RDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNT 5flx a 3.90 BS01 ZN a 1 T24 N25 A27 T23 N24 A26 P62854 26604301 TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPP 5flx b 3.90 BS01 NUC z 1 D34 K36 C40 Y41 I43 F79 R80 K82 D31 K33 C37 Y38 I40 F76 R77 K79 P42677 26604301 AKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQ 5flx c 3.90 BS01 NUC z 1 K16 L18 Q29 R31 E33 D36 D37 T38 S39 R40 S41 R66 R67 K10 L12 Q23 R25 E27 D30 D31 T32 S33 R34 S35 R60 R61 P62857 26604301 QPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARR 5flx d 3.90 BS01 ZN d 1 V23 C24 C39 C42 V19 C20 C35 C38 P62273 26604301 QLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKL 5flx e 3.90 BS01 NUC z 1 F49 K51 K52 F47 K49 K50 P62861 26604301 HGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNA 5fp6 A 1.85 BS01 MFZ A 1 I10 E12 V18 A31 F80 E81 F82 L83 L134 D145 I10 E12 V18 A31 F80 E81 F82 L83 L134 D145 2.7.11.22 P24941 26655740 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 5fp6 A 1.85 BS02 MFZ A 2 L37 T41 E42 P45 A48 I49 I52 V69 H71 L76 L37 T41 E42 P45 A48 I49 I52 V69 H71 L76 2.7.11.22 P24941 26655740 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 5fpe A 1.96 BS01 3TR A 1 K273 S277 G341 I345 K266 S270 G334 I338 P54652 26655740 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIG 5fpe A 1.96 BS02 3TR A 2 Y149 D208 T224 A225 G226 T228 Y146 D201 T217 A218 G219 T221 P54652 26655740 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIG 5fpe B 1.96 BS01 3TR B 1 Y149 D208 T224 A225 G226 Y146 D205 T221 A222 G223 P54652 26655740 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIG 5fpn A 1.96 BS01 KYD A 1 R49 E118 S121 M122 T125 I164 R46 E115 S118 M119 T122 I161 P54652 26655740 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIG 5fpn A 1.96 BS02 KYD A 2 K273 R274 S277 G341 S342 R344 I345 K268 R269 S272 G336 S337 R339 I340 P54652 26655740 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIG 5fpn B 1.96 BS02 KYD B 2 R49 S121 M122 T125 I164 R46 S118 M119 T122 I161 P54652 26655740 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIG 5fpo A 1.83 BS01 10L A 1 L82 E110 Y219 V281 K283 L79 E107 Y215 V277 K279 6.5.1.2,6.5.1.1 Q9AIU7 26655740 DLSSRVNELHDLLNQYSYEYYVENPSVPDSEYDKLLHELIKIEEEHPEYKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFP 5fpo A 1.83 BS02 10L A 2 N16 S19 Y20 H150 A151 I152 P153 G243 N14 S17 Y18 H147 A148 I149 P150 G239 6.5.1.2,6.5.1.1 Q9AIU7 26655740 DLSSRVNELHDLLNQYSYEYYVENPSVPDSEYDKLLHELIKIEEEHPEYKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFP 5fpo A 1.83 BS03 10L A 3 R172 F175 A191 N192 P193 D276 R169 F172 A187 N188 P189 D272 6.5.1.2,6.5.1.1 Q9AIU7 26655740 DLSSRVNELHDLLNQYSYEYYVENPSVPDSEYDKLLHELIKIEEEHPEYKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFP 5fps A 2.68 BS01 UP8 A 1 G207 S208 G209 S211 T212 F238 R467 G218 S219 G220 S222 T223 F249 R478 3.4.21.- P26663 26655740 GSVVIVGRIILSGSGSITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCTRGVAKAVDFVPVESMETTMRSPTDNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGIDPNIRTGVRTITTGAPVTYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSNTGEIPFYGKAIPIEAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGLDVSVIPTIGDVVVVATDALMTGYTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRRGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWESVFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMACMSADLEVVT 5fps B 2.68 BS01 UP8 B 1 G207 S208 G209 S211 T212 F238 G218 S219 G220 S222 T223 F249 3.4.21.- P26663 26655740 GSVVIVGRIILSSITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCTRGVAKAVDFVPVESMETTMRSPVFTDNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGIDPNIRTGVRTITTGAPVTYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSNTGEIPFYGKAIPIEAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGLDVSVIPTIGDVVVVATDALMTGYTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRRGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWESVFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMACMSADLEVVT 5fpt A 2.72 BS01 3VY A 1 T254 G255 T269 G271 K272 A275 W501 Y502 T268 G269 T283 G285 K286 A289 W515 Y516 3.4.21.- P26663 26655740 GSVVIVGRIILSGSGSITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCTRGVAKAVDFVPVESMETTMRSPVFTDNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGIDPNIRTGVRTITTGAPVTYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSNTGEIPFYGKAIPIEAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGLDVSVIPTIGDVVVVATDALMTGYTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRRGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWESVFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMACMSADLEVVT 5fpt B 2.72 BS01 3VY B 1 V232 T254 G255 T269 G271 A275 W501 Y502 V243 T265 G266 T280 G282 A286 W512 Y513 3.4.21.- P26663 26655740 GSVVIVGRIILSSITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCTRGVAKAVDFVPVESMETTMRSPVFTDNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGIDPNIRTGVRTITTGAPVTYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSNTGEIPFYGKAIPIEAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGLDVSVIPTIGDVVVVATDALMTGYTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRRGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWESVFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMACMSADLEVVT 5fpy A 2.52 BS01 R2N A 1 S370 K371 V432 Q434 T448 N556 S384 K385 V446 Q448 T462 N570 3.4.21.- P26663 26655740 GSVVIVGRIILSGSGSITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCTRGVAKAVDFVPVESMETTMRSPVFTDNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGIDPNIRTGVRTITTGAPVTYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSNTGEIPFYGKAIPIEAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGLDVSVIPTIGDVVVVATDALMTGYTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRRGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWESVFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMACMSADLEVVT 5fpy B 2.52 BS01 R2N B 1 S370 K371 V432 Q434 T448 S381 K382 V443 Q445 T459 3.4.21.- P26663 26655740 GSVVIVGRIILSSITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCTRGVAKAVDFVPVESMETTMRSPVFTDNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGIDPNIRTGVRTITTGAPVTYSTYGKFLADGGCSGGAYDIIICDECHSTDSTTILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSNTGEIPFYGKAIPIEAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGLDVSVIPTIGDVVVVATDALMTGYTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRRGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWESVFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMACMSADLEVVT