2ms4 A BS01 III B 1 R55 I57 P58 G59 F60 M61 Q63 G72 T73 A101 N102 A103 S110 Q111 F113 W121 L122 R148 R55 I57 P58 G59 F60 M61 Q63 G72 T73 A101 N102 A103 S110 Q111 F113 W121 L122 R148 5.2.1.8 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 2n01 B BS01 III A 1 Y165 Y167 D168 Y169 A170 T171 R172 P180 S181 R182 Y184 R210 E213 D217 V239 V246 G248 L249 R250 Y16 Y18 D19 Y20 A21 T22 R23 P31 S32 R33 Y35 R61 E64 D68 V90 V97 G99 L100 R101 Q8PJB5 GSHMNAKILKDRRYYYDYDYATRTKKSWLIPSRVYDDGKFTYINMDLTRFPTGNFPAVFAREKEHAEDFLVNTTVEGNTLIVHGTYPFLVVRHGDNVVGLRRNKQK 2rui A BS01 III B 1 S59 L103 V110 A124 G125 H126 P168 K170 W171 V173 V174 I185 T186 C187 R196 S7 L51 V58 A72 G73 H74 P116 K118 W119 V121 V122 I133 T134 C135 R144 Q6I399 GSHMDASKIDQPDLAEVANASLDKKQVIGRISIPSVSLELPVLKSSTEKNLLSGAATVKENQVMGKGNYALAGHNMSKKGVLFSDIASLKKGDKIYLYDNENEYEYAVTGVSEVTPDKWEVVEDHGKDEITLITCVSVKDNSKRYVVAGDLVGTKAKK 3jad A 3.90 BS01 SY9 A 1 F60 F79 R81 L133 R135 L143 F36 F55 R57 L109 R111 L119 APSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKLV 3jad A 3.90 BS02 SY9 B 1 F175 G176 Y218 T220 F223 F151 G152 Y194 T196 F199 APSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKLV 3jaf A 3.80 BS01 IVM A 1 T280 S283 R287 V296 A304 L307 T256 S259 R263 V272 A280 L283 APSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARAGTKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKLVPR 3jaf A 3.80 BS02 IVM E 1 L240 I241 I245 P246 L249 L216 I217 I221 P222 L225 APSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARAGTKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKLVPR 4d4n A 1.45 BS01 HEC A 1 R12 Q13 L16 T17 M19 A20 W56 F59 G66 D67 I72 F79 K82 Q83 F86 C116 C119 Y123 R124 R12 Q13 L16 T17 M19 A20 W56 F59 G66 D67 I72 F79 K82 Q83 F86 C116 C119 Y123 R124 P00138 26100643 EFAKPEDAVKYRQSALTLMASHFGRMTPVVKGQAPYDAAQIKANVEVLKTLSALPWAAFGPGTEGGDARPEIWSDAASFKQKQQAFQDNIVKLSAAADAGDLDKLRAAFGDVGASCKACHAAYRK 4d4x A 1.30 BS01 HEC A 1 R12 Q13 L16 T17 M19 A20 F23 W56 F59 D67 A68 I72 F79 Q83 F86 C116 C119 Y123 R124 R12 Q13 L16 T17 M19 A20 F23 W56 F59 D67 A68 I72 F79 Q83 F86 C116 C119 Y123 R124 P00138 26100643 EFAKPEDAVKYRQSALTLMASHFGRMTPVVKGQAPYDAAQIKANVEVLKTLSALPWAAFGPGTEGGDARPEIWSDAASFKQKQQAFQDNIVKLSAAADAGDLDKLRAAFGDVGASCKACHIAYRKK 4oyn A 1.43 BS02 FE A 2 E62 E107 Q141 E58 E103 Q137 1.16.3.1 P02794 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 4r6e A 2.20 BS01 3JD A 1 A762 D766 H862 G863 G888 Y889 Y896 F897 K903 S904 Y907 E988 A102 D106 H202 G203 G228 Y229 Y236 F237 K243 S244 Y247 E328 2.4.2.30 P09874 MKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 4r6e C 2.20 BS01 3JD C 1 D766 H862 G863 G888 Y889 Y896 F897 S904 Y907 D106 H202 G203 G228 Y229 Y236 F237 S244 Y247 2.4.2.30 P09874 MKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 4r6e D 2.20 BS01 3JD D 1 D766 H862 G863 G888 Y889 Y896 F897 A898 S904 Y907 E988 D104 H200 G201 G226 Y227 Y234 F235 A236 S242 Y245 E326 2.4.2.30 P09874 SKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 4ra3 A 2.80 BS01 TFX A 1 Y26 S52 S55 S57 Y63 Y27 S53 S56 S58 Y64 P61769 MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPCDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM 4ra3 B 2.80 BS01 TFX B 1 Y26 S55 S57 Y63 L65 Y26 S55 S57 Y63 L65 P61769 IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPCDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDR 4ra3 B 2.80 BS02 TFX B 2 Q8 Y10 Q8 Y10 P61769 IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPCDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDR 4ra3 C 2.80 BS01 TFX C 1 Q8 Y10 S11 H13 P14 M99 Q8 Y10 S11 H13 P14 M99 P61769 IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPCDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM 4re8 A 2.16 BS01 3MJ A 1 F158 L162 L165 V167 L175 L178 V179 I181 T182 Q197 L224 K227 L228 L231 F128 L132 L135 V137 L145 L148 V149 I151 T152 Q167 L190 K193 L194 L197 P22736 26235054 ANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 4ree A 2.37 BS01 3MZ A 1 L118 L175 L178 T182 Q197 L224 K227 L228 L89 L146 L149 T153 Q168 L191 K194 L195 P22736 26235054 PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 4ref A 2.10 BS01 3N0 A 1 L175 L178 V179 I181 T182 Q197 L224 L225 L228 L145 L148 V149 I151 T152 Q167 L188 L189 L192 P22736 26235054 ANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFIWRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 4rpm A 1.40 BS01 6NA A 1 P21 H22 C155 A156 I272 P21 H22 C155 A156 I272 Q2GWK9 26172141 MISVADLDYASRKSSIFLFAPHVGTFTKQSMDKLVRPLAASAHRDWILDTVAGLPTYWDALAVKIPNIGNAIPGRRQLTDLDTWFRHGAGDVTQDDATLPSIVVGPLVVLIQLTQYWRYLELTRPDHLEDSADLQADVVTRQTQPGAKVETLGFCAGLLAAVAVASAGNRQEFQKYGAVAVRLAMMAGALIDGQEARDKATRDGGSVSYAIAWRGQKPGEEAARIVKDLNPNAYFAVLYDEARATVTTTRRTAPSLVNRLRAADVTVAEIGIKGRIHSPDSERKNNTDLLVDLCKSFEDLQYADAASLALPTYNNEAEGRPVSRDRGNMTEMVIRAILVNQCNWYGTFKGATEGREPFVVTLGLERSVPPTLMRSLGPHQVHYEDLADNGIPPAP 4rpm A 1.40 BS02 HXC A 1 P21 H22 V23 F154 C155 A236 V237 Y239 T245 I270 I272 I276 H277 P21 H22 V23 F154 C155 A236 V237 Y239 T245 I270 I272 I276 H277 Q2GWK9 26172141 MISVADLDYASRKSSIFLFAPHVGTFTKQSMDKLVRPLAASAHRDWILDTVAGLPTYWDALAVKIPNIGNAIPGRRQLTDLDTWFRHGAGDVTQDDATLPSIVVGPLVVLIQLTQYWRYLELTRPDHLEDSADLQADVVTRQTQPGAKVETLGFCAGLLAAVAVASAGNRQEFQKYGAVAVRLAMMAGALIDGQEARDKATRDGGSVSYAIAWRGQKPGEEAARIVKDLNPNAYFAVLYDEARATVTTTRRTAPSLVNRLRAADVTVAEIGIKGRIHSPDSERKNNTDLLVDLCKSFEDLQYADAASLALPTYNNEAEGRPVSRDRGNMTEMVIRAILVNQCNWYGTFKGATEGREPFVVTLGLERSVPPTLMRSLGPHQVHYEDLADNGIPPAP 4rz8 A 1.90 BS01 3ZM A 1 V255 T257 D368 E370 S375 F376 N377 F382 I424 N425 M426 W427 Q428 G429 V139 T141 D229 E231 S236 F237 N238 F243 I271 N272 M273 W274 Q275 G276 Q0ED31 26301736 VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQLFNNTCINGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE 4rz8 B 1.90 BS01 3ZM B 1 V255 S256 T257 D368 E370 S375 F376 N377 F382 I424 N425 M426 W427 Q428 G429 V139 S140 T141 D229 E231 S236 F237 N238 F243 I266 N267 M268 W269 Q270 G271 Q0ED31 26301736 VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQLFNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE 4ue4 C 7.00 BS01 NUC A 1 K381 S382 M383 T384 S397 R398 R401 K404 G405 K52 S53 M54 T55 S68 R69 R72 K75 G76 P37105 TLDDFLEQLGQVRNMGPLDELLQMMPGAGKMKGLKNIQVDEKQLNHVEAIIKSMTVLEKEQPDIINASRRKRIAKGSGTSVQEVNRLLKQFDEMKKMMKQMT 4ue5 B 9.00 BS01 NUC A 1 V2 G63 V1 G43 VLLESEQFLTELTRLFQKCRLSGSVFITLKKYDNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLK 4ue5 C 9.00 BS01 NUC A 1 Q64 F72 Q73 R76 S80 Q83 R87 K88 M121 D122 R125 A126 Y129 A137 E140 P141 R142 K143 R144 F145 H146 L147 L148 S149 R150 L151 R152 K153 A154 K156 H157 Q15 F23 Q24 R27 S31 Q34 R38 K39 M56 D57 R60 A61 Y64 A72 E75 P76 R77 K78 R79 F80 H81 L82 L83 S84 R85 L86 R87 K88 A89 K91 H92 Q00004 LSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNDLLTDNRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIG 4ue5 D 9.00 BS01 NUC A 1 G409 S410 G411 G409 S410 G411 P61010 MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKK 4ue5 D 9.00 BS02 III S 1 M351 I352 M351 I352 P61010 MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKK 4ue5 E 9.00 BS01 NUC A 1 A2 D45 L46 C48 A1 D44 L45 C47 P21262 AQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGSLCIKVTDDLVCLVYRTDQAQDVKKIEKFHSQLMRLMVA 4w63 A 2.80 BS01 HTB A 1 W84 G118 G119 Y121 E199 S200 W233 F290 F330 F331 V395 N399 V400 W432 H440 G441 Y442 W83 G117 G118 Y120 E198 S199 W232 F289 F329 F330 V394 N398 V399 W431 H439 G440 Y441 3.1.1.7 P04058 DHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 4w8h A 1.14 BS01 III D 1 R152 Q178 I179 I180 D217 N220 R59 Q85 I86 I87 D124 N127 A6M946 GKTYDVNICYAPEDREWVINTLVFKLERAGIKTFVNIRDDTPGNFFAENIMDAIENSNRTIVVMSPDFFKNNICDKTLQIGLSHQIIPILYRPCEVPYFLNHMTYLDWCDKDVRPVFWRNLFRDIRN 4w9z A 1.30 BS01 CU A 1 H194 C229 C233 M240 H68 C103 C107 M114 1.9.3.1 H7C6E5 MVPKADLTIKATGKQWYWSYAYPDNGKFEFDSLMAQDKQPRLLGVDNEMVVPVNKVIRVQVTGADVIHAFALPAFGVKIDAIPGRLNETWFKAAKTGMFYGQCSELCGKDHAFMPIAIRVVEDKEFASWVETAKKKFA 4w9z A 1.30 BS02 CU A 2 C229 E231 C233 H237 C103 E105 C107 H111 1.9.3.1 H7C6E5 MVPKADLTIKATGKQWYWSYAYPDNGKFEFDSLMAQDKQPRLLGVDNEMVVPVNKVIRVQVTGADVIHAFALPAFGVKIDAIPGRLNETWFKAAKTGMFYGQCSELCGKDHAFMPIAIRVVEDKEFASWVETAKKKFA 4wd4 A 2.95 BS01 HEM A 1 R25 E29 M34 Q38 Y134 T135 G139 S142 G143 L147 K179 R183 F207 N210 R16 E20 M25 Q29 Y125 T126 G130 S133 G134 L138 K170 R174 F198 N201 1.14.99.3 P09601 PQDLSEALKEATKEVRTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTH 4wd4 B 2.95 BS01 HEM B 1 K18 E29 M34 Q38 Y134 T135 G139 S142 G143 L147 R183 F207 F214 K9 E20 M25 Q29 Y125 T126 G130 S133 G134 L138 R174 F198 F205 1.14.99.3 P09601 PQDLSEALKEATKEVRTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTH 4wd4 D 2.95 BS01 HEM D 1 K18 E29 M34 Q38 Y134 T135 G139 S142 G143 L147 K179 F207 N210 F214 K9 E20 M25 Q29 Y125 T126 G130 S133 G134 L138 K170 F198 N201 F205 1.14.99.3 P09601 PQDLSEALKEATKEVRTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTH 4wf6 A 2.65 BS02 407 A 1 D328 S655 K656 G657 L658 V675 L677 H686 E687 H690 Y728 E735 E739 R742 D63 S382 K383 G384 L385 V402 L404 H413 E414 H417 Y455 E462 E466 R469 3.4.24.83 P15917 SRYEKWEKIKQHYQHWSDSLSEEGRGLLKKLQIPIEPKKDDIIHSLSQEEKELLKRIQIDSSDFLSTEEKEFLKKLQIDIRDSLSEEEKELLNPLSEKEKEFLKKLKLDIQPYDINQRLQDTGGLIDSPSINLDVRKQYKRDIQNIDALLHQSIGSTLYNKIYLYENMNINNLTATLGADLVDSTDNTKINRGIFNEFKKNFKYSISSNYMIVDINERPALDNERLKWRIQLSPDTRAGYLENGKLILQRNIGLEIKDVQIIKQSEKEYIRIDAKVVPKSKIDTKIQEAQLNINQEWNKALGLPKYTKLITFNVHNRYASNIVESAYLILNEWKNNIQSDLIKKVTNYLVDGNGRFVFTDITLPNIAEQYTHQDEIYEQVHSKGLYVPESRSILLHGPSKGVELRNDSEGFIHEFGHAVDDYAGYLLDKNQSDLVTNSKKFIDIFKEEGSNLTSYGRTNEAEFFAEAFRLMHSTDHAERLKVQKNAPKTFQFINDQIKFIINS 4whf A 2.27 BS01 3MX A 1 L118 L162 L165 L178 V179 T182 Q197 L224 L225 K227 L228 R232 L88 L132 L135 L148 V149 T152 Q167 L188 L189 K191 L192 R196 P22736 26235054 ANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 4whg A 2.18 BS01 3NB A 1 L178 V179 I181 T182 Q197 L224 K227 L228 L149 V150 I152 T153 Q168 L191 K194 L195 P22736 26235054 PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF 4wqm A 1.62 BS01 FES A 1 Y34 E35 C36 N37 G39 G40 C41 G42 C44 C76 Y34 E35 C36 N37 G39 G40 C41 G42 C44 C76 1.18.1.3 Q03304 26309236 SFNIQSDDLLHHFEADSNDTLLSAALRAELVFPYECNSGGCGACKIELLEGEVSNLWPDAPGLAARELRKNRFLACQCKPLSDLKIKVINRAEGRASHPPKRFSTRVVSKRFLSDEMFELRLEAEQKVVFSPGQYFMVDVPELGTRAYSAANPVDGNTLTLIVKAVPNGKVSCALANETIETLQLDGPYGLSVLKTADETQSVFIAGGSGIAPMVSMVNTLIAQGYEKPITVFYGSRLEAELEAAETLFGWKENLKLINVSSSVVGNSESSYPTGYVHEIIPEYMEGLLGAEFYLCGPPQMINSVQKLLMIENKVPFEAIHFDRFF 4wqm A 1.62 BS02 FAD A 1 C36 S38 W57 Y135 R146 A147 Y148 S149 I162 V163 K164 V166 G169 K170 V171 S172 S209 A212 R324 F325 C36 S38 W57 Y135 R146 A147 Y148 S149 I162 V163 K164 V166 G169 K170 V171 S172 S209 A212 R324 F325 1.18.1.3 Q03304 26309236 SFNIQSDDLLHHFEADSNDTLLSAALRAELVFPYECNSGGCGACKIELLEGEVSNLWPDAPGLAARELRKNRFLACQCKPLSDLKIKVINRAEGRASHPPKRFSTRVVSKRFLSDEMFELRLEAEQKVVFSPGQYFMVDVPELGTRAYSAANPVDGNTLTLIVKAVPNGKVSCALANETIETLQLDGPYGLSVLKTADETQSVFIAGGSGIAPMVSMVNTLIAQGYEKPITVFYGSRLEAELEAAETLFGWKENLKLINVSSSVVGNSESSYPTGYVHEIIPEYMEGLLGAEFYLCGPPQMINSVQKLLMIENKVPFEAIHFDRFF 4x1f A 2.00 BS01 3WF A 1 D205 L206 L240 M243 S247 F251 H407 R410 I414 M425 D47 L48 L82 M85 S89 F93 H244 R247 I251 M262 O75469 GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS 4x1g A 2.25 BS02 3WG A 1 M243 M246 S247 F281 Q285 F288 W299 Y306 M323 H407 M88 M91 S92 F126 Q130 F133 W144 Y151 M168 H252 O75469 GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS 4x6j A 1.59 BS01 3Y2 A 1 Q19 G23 C25 W26 E59 G64 G65 G66 Y67 A134 L160 N161 Q19 G23 C25 W26 E59 G64 G65 G66 Y67 A134 L160 N161 3.4.22.38 P43235 26280490 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 4xeg A 1.72 BS01 NUC C 1 P155 K246 A274 R275 A277 P280 R281 P45 K136 A164 R165 A167 P170 R171 3.2.2.29 Q13569 FNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERNM 4xeg A 1.72 BS02 NUC D 1 N140 N157 S200 K201 G231 K232 C233 F252 P270 S271 S273 A274 R275 C276 A277 Q278 N30 N47 S90 K91 G121 K122 C123 F142 P160 S161 S163 A164 R165 C166 A167 Q168 3.2.2.29 Q13569 FNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERNM 4xep A 1.50 BS01 MG A 1 D8 D9 N92 D10 D11 N94 3.1.3.5,3.1.3.6,3.6.1.11 P66881 ASMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMAGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAASAHDVVSDWLDSVGVGTQW 4xgp A 1.90 BS02 ADE A 1 D100 A182 I199 G200 P201 P202 D111 A193 I210 G211 P212 P213 3.1.3.5,3.1.3.6,3.6.1.11 P66881 SHHHHHHGMASMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMAGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAASAHDVVSDWLDSVGVGTQW 4xj7 A 1.60 BS02 ADN A 1 G40 N96 D100 Y103 S104 A182 I199 G200 P202 G50 N106 D110 Y113 S114 A192 I209 G210 P212 3.1.3.5,3.1.3.6,3.6.1.11 P66881 HHHHHHGMASMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMAGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW 4xj7 B 1.60 BS01 ADN A 1 L45 L47 Y73 L51 L53 Y79 3.1.3.5,3.1.3.6,3.6.1.11 P66881 HHGMASMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMAGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW 4xj7 B 1.60 BS03 ADE B 1 Y103 A182 I199 G200 P201 P202 Y109 A188 I205 G206 P207 P208 3.1.3.5,3.1.3.6,3.6.1.11 P66881 HHGMASMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMAGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW 4xj7 C 1.60 BS02 ADN D 1 L45 L47 L46 L48 3.1.3.5,3.1.3.6,3.6.1.11 P66881 SMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMAGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW 4xj7 D 1.60 BS02 ADN D 1 G40 P95 N96 D100 Y103 S104 I199 G200 P202 G41 P96 N97 D101 Y104 S105 I200 G201 P203 3.1.3.5,3.1.3.6,3.6.1.11 P66881 SMRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMAGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW 4y29 A 1.98 BS01 III B 1 T297 K301 F306 L311 Q314 V315 L318 P467 L468 E471 T78 K82 F87 L92 Q95 V96 L99 P248 L249 E252 P37231 26183621 SADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDL 4y29 A 1.98 BS02 CTI A 1 I281 C285 R288 S289 I326 L330 L333 L340 I341 L353 L356 F360 M364 I62 C66 R69 S70 I107 L111 L114 L121 I122 L134 L137 F141 M145 P37231 26183621 SADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDL 4y9b B 1.40 BS01 MKS B 1 K15 L17 A108 L110 T119 K6 L8 A99 L101 T110 P02766 26310724 CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN 4y9c A 1.49 BS02 BR A 1 K35 W41 I68 V94 K26 W32 I59 V85 P02766 26310724 CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN 4y9c B 1.49 BS01 BR B 1 K35 I68 V94 K26 I59 V85 P02766 26310724 CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSRYTIAALLSPYSYSTTAVVTN 4y9c B 1.49 BS02 MKS B 1 K15 L17 P24 A108 S117 T119 K6 L8 P15 A96 S105 T107 P02766 26310724 CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSRYTIAALLSPYSYSTTAVVTN 4y9f B 1.50 BS01 MKT B 1 K15 L17 P24 A108 L110 S117 T119 K6 L8 P15 A96 L98 S105 T107 P02766 26310724 CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSRYTIAALLSPYSYSTTAVVTN 4y9g A 1.89 BS01 MKU A 1 M13 K15 L17 T106 A108 A109 L110 S117 T119 V121 M4 K6 L8 T97 A99 A100 L101 S108 T110 V112 P02766 26310724 CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 4y9g B 1.89 BS01 MKU B 1 K15 L17 A108 L110 T119 V121 K6 L8 A99 L101 T110 V112 P02766 26310724 CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN 4yih A 1.82 BS02 2O2 A 1 D12 F18 F44 L45 A46 R47 Y65 S100 L102 L103 R132 D9 F15 F41 L42 A43 R44 Y62 S97 L99 L100 R129 3.1.3.- Q8TCD5 SVRVLVDMDGVLADFEAGLLRGFRRRFPEEPHVPLEQRRGFLAREQYRALRPDLADKVASVYEAPGFFLDLEPIPGALDAVREMNDLPDTQVFICTSPLLKYHHCVGEKYRWVEQHLGPQFVERIILTRDKTVVLGDLLIDDKDTVRGQEETPSWEHILFTCCHNRHLVLPPTRRRLLSWSDNWREILDSKR 4yik A 1.48 BS02 2O2 A 1 D41 D43 F49 F75 W76 V77 W96 S131 I133 K134 R163 D15 D17 F23 F49 W50 V51 W70 S105 I107 K108 R137 3.1.3.- Q9NPB1 SNAASGGRALRVLVDMDGVLADFEGGFLRKFRARFPDQPFIALEDRRGFWVSEQYGRLRPGLSEKAISIWESKNFFFELEPLPGAVEAVKEMASLQNTDVFICTSPIKMFKYCPYEKYAWVEKYFGPDFLEQIVLTRDKTVVSADLLIDDRPDITGAEPTPSWEHVLFTACHNQHLQLQPPRRRLHSWADDWKAILDSKRP 4yuv A 1.60 BS01 S4M A 1 Q40 L59 Q64 Y73 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 T170 P175 A176 L179 Y237 Q31 L50 Q55 Y64 H65 G86 D89 V108 D109 I110 D111 V114 D140 G141 D159 T160 T161 P166 A167 L170 Y228 2.5.1.16 Q4DA73 ISGGWFREENPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuw A 1.97 BS02 4JU A 1 I63 Q64 Y73 T169 D171 Q201 Y237 P238 I242 I63 Q64 Y73 T169 D171 Q201 Y237 P238 I242 2.5.1.16 Q4DA73 MPGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuw B 1.97 BS01 S4M B 1 Q40 M57 L59 Q64 V65 Y73 H74 G95 D98 D118 I119 D120 V123 D149 G150 D168 T169 T170 P175 A176 L179 Y237 Q40 M57 L59 Q64 V65 Y73 H74 G95 D98 D118 I119 D120 V123 D149 G150 D168 T169 T170 P175 A176 L179 Y237 2.5.1.16 Q4DA73 MPGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuw B 1.97 BS02 4JU B 1 W19 Q64 Y73 T169 D171 Q201 Y237 P238 I242 W19 Q64 Y73 T169 D171 Q201 Y237 P238 I242 2.5.1.16 Q4DA73 MPGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yux A 1.60 BS02 4JT A 1 I63 Q64 Y73 T169 Q201 T236 Y237 I242 I62 Q63 Y72 T168 Q200 T235 Y236 I241 2.5.1.16 Q4DA73 PGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuy A 1.58 BS02 1SQ A 1 I63 Q64 Y73 T169 Q201 V234 T236 Y237 I62 Q63 Y72 T168 Q200 V233 T235 Y236 2.5.1.16 Q4DA73 PGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuz A 1.97 BS01 S4M A 1 Q40 L59 Q64 V65 H74 I94 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 T170 Q31 L50 Q55 V56 H65 I85 G86 D89 V108 D109 I110 D111 V114 D140 G141 D159 T160 T161 2.5.1.16 Q4DA73 GWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuz A 1.97 BS02 4JV B 1 E14 W19 Q22 L207 P238 C239 E5 W10 Q13 L186 P217 C218 2.5.1.16 Q4DA73 GWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuz B 1.97 BS01 S4M B 1 Q40 L59 Q64 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 Q32 L51 Q56 H66 G87 D90 V109 D110 I111 D112 V115 D141 G142 D160 T161 2.5.1.16 Q4DA73 ELISGGWFREEPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuz B 1.97 BS02 4JV B 1 E14 M24 S25 W53 P235 T236 E10 M16 S17 W45 P217 T218 2.5.1.16 Q4DA73 ELISGGWFREEPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuz C 1.97 BS01 S4M C 1 Q40 M57 L59 Q64 Y73 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 T170 Q32 M49 L51 Q56 Y65 H66 G87 D90 V109 D110 I111 D112 V115 D141 G142 D160 T161 T162 2.5.1.16 Q4DA73 ISGGWFREENDPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuz C 1.97 BS02 4JV D 1 E14 E15 Q22 P238 C239 E8 E9 Q14 P218 C219 2.5.1.16 Q4DA73 ISGGWFREENDPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuz D 1.97 BS01 S4M D 1 Q40 M57 L59 Q64 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 Q34 M51 L53 Q58 H68 G89 D92 V111 D112 I113 D114 V117 D143 G144 D162 T163 2.5.1.16 Q4DA73 ELISGGWFREENDPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yuz D 1.97 BS02 4JV D 1 E14 M24 S25 L26 W53 P235 T236 E10 M18 S19 L20 W47 P218 T219 2.5.1.16 Q4DA73 ELISGGWFREENDPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yw6 A 1.40 BS02 G0P A 1 Y36 P38 H50 Q53 C62 D100 V101 T104 N107 Y36 P38 H50 Q53 C62 D100 V101 T104 N107 Q05097 26295304 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4yw7 C 1.82 BS01 4J0 C 1 Y36 P38 T39 H50 Q53 C62 D100 V101 T104 N107 Y36 P38 T39 H50 Q53 C62 D100 V101 T104 N107 Q05097 26295304 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4yw7 I 1.82 BS02 4J0 I 1 Y36 H50 C62 D100 V101 T104 N107 Y36 H50 C62 D100 V101 T104 N107 Q05097 26295304 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4ywa A 1.19 BS02 4J9 A 1 Y36 Q40 H50 Q53 C62 D100 V101 T104 N107 Y36 Q40 H50 Q53 C62 D100 V101 T104 N107 Q05097 26295304 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4z4p A 2.20 BS01 ZN A 1 C5477 C5525 C5527 C5532 C98 C146 C148 C153 2.1.1.43 O14686 26320581 TLHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHEIPCHCGAWNCRKWMKGHH 4z4p A 2.20 BS02 SAH A 1 I5406 Q5407 G5408 L5409 Y5451 R5471 Y5472 N5474 H5475 Y5512 I5523 P5524 C5525 H5526 C5527 M5536 H5539 I27 Q28 G29 L30 Y72 R92 Y93 N95 H96 Y133 I144 P145 C146 H147 C148 M157 H160 2.1.1.43 O14686 26320581 TLHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHEIPCHCGAWNCRKWMKGHH 4zbp C 2.60 BS01 ADV C 1 T138 G139 V140 D184 F186 E204 T121 G122 V123 D167 F169 E187 3.6.1.-,3.6.1.13,3.6.1.22 Q9SU14 26253775 QQIPLLEGETDNYDGVTVTMVEPMDSEVFTESLRASLSHWREEGKKGIWIKLPLGLANLVEAAVSEGFRYHHAEPEYLMLVSWISETPDTIPANASHVVGAGALVINKNTKEVLVVWKLPTGVINEGEDIWTGVAREVEEETGIIADFVEVLAFRQSHKAILKKKTDMFFLCVLSPRSYDITEQKSEILQAKWMPIQEYVDQPWNKKNEMFKFMANICQKKCEEEYLGFAIVPTTTSSGKESFIYCNADHAKRLKVSRDQAS 4zbx A 1.70 BS01 SF4 A 1 C14 K16 C17 L19 W20 R23 V84 C86 A101 C102 Y105 C14 K16 C17 L19 W20 R23 V84 C86 A101 C102 Y105 3.2.2.27 Q96YD0 MDSLEKIKEEVISCKKCKLWQFRTNAVPGEGYPKAEIMFVGEAPGENEDKEGRPFVGAAGKLLTQMIKEILGLERDQVFITNVVKCRPPNNRDPEEDEITACSPYLDRQIDIIMPKIIVTLGRHSTKYIFSKMGENFSSITKVRGKSYVWKYKEKEIIVFPTYHPAAALYNPNLRKILEEDFKKIRELAITP 4zby A 1.70 BS02 URA A 1 E42 A43 E48 P54 F55 N82 H164 E42 A43 E48 P54 F55 N82 H164 3.2.2.27 Q96YD0 MDSLEKIKEEVISCKKCKLWQFRTNAVPGEGYPKAEIMFVGEAPGENEDKEGRPFVGAAGKLLTQMIKEILGLERDQVFITNVVKCRPPNNRDPEEDEITACSPYLDRQIDIIMPKIIVTLGRHSTKYIFSKMGENFSSITKVRGKSYVWKYKEKEIIVFPTYHPAAALYNPNLRKILEEDFKKIRELAITPKR 4zdr A 2.90 BS01 TME A 1 E14 L43 E21 L50 Q15831 LYKKAGLMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSRSMEVVPY 4zdr A 2.90 BS02 TME A 2 K3 Q32 K10 Q39 Q15831 LYKKAGLMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSRSMEVVPY 4zdr B 2.90 BS01 TME B 1 I93 D96 I99 D102 Q15831 SLYKKAGLMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSESYKDSTLIMQLLRDNLTLWTSGSRSME 4zdr B 2.90 BS02 TME B 2 R60 M239 R68 M240 Q15831 SLYKKAGLMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSESYKDSTLIMQLLRDNLTLWTSGSRSME 4zev A 1.80 BS01 MG A 1 D29 D238 D31 D240 Q8IJ74 HHMHEIVDKNGKKVQKNNLNDEIKIIFTALDGTLLNSENKVSEQNLESLIRAQEKGIKVVIATGRSIFSVENVIGEHVKKNRISLLPGIYMNGCVTFDEKGSRVIDRIMNNDLKMEIHEFSKQINISKYAIWFCLEKTYCFEINDCIREYMEVEALNPDVIEDNMLEGLTVYKVLFSLPENILENTLKLCREKFSHRINVANTFQSYVELFHQHTNKFEGVKEICKYYNISLNNALAMGDGENDIEMLSGLTHSVGVHNASEKVKNSAAYVGPSNNEHAISHVLKTFCDI 4zev A 1.80 BS02 M6P A 1 A27 L28 D29 T61 G62 R63 E152 L173 T201 F202 Y205 E207 K215 N241 A29 L30 D31 T63 G64 R65 E154 L175 T203 F204 Y207 E209 K217 N243 Q8IJ74 HHMHEIVDKNGKKVQKNNLNDEIKIIFTALDGTLLNSENKVSEQNLESLIRAQEKGIKVVIATGRSIFSVENVIGEHVKKNRISLLPGIYMNGCVTFDEKGSRVIDRIMNNDLKMEIHEFSKQINISKYAIWFCLEKTYCFEINDCIREYMEVEALNPDVIEDNMLEGLTVYKVLFSLPENILENTLKLCREKFSHRINVANTFQSYVELFHQHTNKFEGVKEICKYYNISLNNALAMGDGENDIEMLSGLTHSVGVHNASEKVKNSAAYVGPSNNEHAISHVLKTFCDI 4zev B 1.80 BS02 PO4 B 1 L28 D29 T61 G62 K215 N241 L11 D12 T44 G45 K198 N224 Q8IJ74 NDEIKIIFTALDGTLLNSENKVSEQNLESLIRAQEKGIKVVIATGRSIFSVENVIGEHVKKNRISLLPGIYMNGCVTFDEKGSRVIDRIMNNDLKMEIHEFSKQINISKYAIWFCLEKTYCFEINDCIREYMEVEALNPDVIEDNMLEGLTVYKVLFSLPENILENTLKLCREKFSHRINVANTFQSYVELFHQHTNKFEGVKEICKYYNISLNNALAMGDGENDIEMLSGLTHSVGVHNASEKVKNSAAYVGPSNNEHAISHVLKTFCD 4zex A 2.00 BS02 G3H A 1 L28 D29 T61 G62 E152 T201 F202 Y205 E207 K215 N241 L30 D31 T63 G64 E154 T203 F204 Y207 E209 K217 N243 Q8IJ74 HHMHEIVDKNGKKVQKNNLNDEIKIIFTALDGTLLNSENKVSEQNLESLIRAQEKGIKVVIATGRSIFSVENVIGEHVKKNRISLLPGIYMNGCVTFDEKGSRVIDRIMNNDLKMEIHEFSKQINISKYAIWFCLEKTYCFEINDCIREYMEVEALNPDVIEDNMLEGLTVYKVLFSLPENILENTLKLCREKFSHRINVANTFQSYVELFHQHTNKFEGVKEICKYYNISLNNALAMGDGENDIEMLSGLTHSVGVHNASEKVKNSAAYVGPSNNEHAISHVLKTFCDI 4zex B 2.00 BS01 MG B 1 A27 D29 D238 A10 D12 D221 Q8IJ74 NDEIKIIFTALDGTLLNSENKVSEQNLESLIRAQEKGIKVVIATGRSIFSVENVIGEHVKKNRISLLPGIYMNGCVTFDEKGSRVIDRIMNNDLKMEIHEFSKQINISKYAIWFCLEKTYCFEINDCIREYMEVEALNPDVIEDNMLEGLTVYKVLFSLPENILENTLKLCREKFSHRINVANTFQSYVELFHQHTNKFEGVKEICKYYNISLNNALAMGDGENDIEMLSGLTHSVGVHNASEKVKNSAAYVGPSNNEHAISHVLKTFCD 4zgm A 1.80 BS01 III B 1 S31 L32 T35 W39 E68 Y69 Y88 L89 P90 W91 R121 L123 E128 S3 L4 T7 W11 E40 Y41 Y60 L61 P62 W63 R93 L95 E100 P43220 26308095 TVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEE 4zgm A 1.80 BS02 32M A 1 L111 W120 L83 W92 P43220 26308095 TVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEE 4zgm A 1.80 BS03 32M B 1 L32 V36 L4 V8 P43220 26308095 TVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEE 4zn9 A 2.22 BS02 OBH A 1 M343 L346 A350 E353 L387 M388 L391 R394 F404 G420 M421 I424 G521 H524 L525 M39 L42 A46 E49 L83 M84 L87 R90 F100 G116 M117 I120 G204 H207 L208 P03372 22517684 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLHAPTS 4zn9 B 2.22 BS02 OBH B 1 L346 A350 E353 L387 M388 L391 R394 F404 M421 I424 G521 H524 L525 L540 L42 A46 E49 L83 M84 L87 R90 F100 M117 I120 G202 H205 L206 L221 P03372 22517684 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLHAPTS 5a2w A 2.50 BS01 AGS A 1 F224 G225 S226 D239 F372 N472 I480 F174 G175 S176 D189 F313 N413 I421 F1NBW0 26319014 KKTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKAAEHHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHKKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a2w B 2.50 BS01 AGS B 1 F224 G225 S226 C236 D237 D239 N371 F372 N472 I480 F173 G174 S175 C185 D186 D188 N311 F312 N412 I420 F1NBW0 26319014 KTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKAAEHHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHKKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a2w B 2.50 BS02 MG B 1 S226 D237 D239 S175 D186 D188 F1NBW0 26319014 KTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKAAEHHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHKKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a2x A 3.10 BS01 CTP A 1 F224 G225 S226 D239 A327 C330 N371 F372 F174 G175 S176 D189 A268 C271 N312 F313 F1NBW0 26319014 KKTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKAAEHHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHDKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a2x B 3.10 BS01 CTP B 1 F224 S226 D239 A327 C330 S331 F372 F170 S172 D185 A266 C269 S270 F311 F1NBW0 26319014 RKKTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKHVVPYKSRLFTFTLKNPGSQAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHDMKKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPFG 5a2x B 3.10 BS02 MG B 1 D237 D239 D183 D185 F1NBW0 26319014 RKKTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKHVVPYKSRLFTFTLKNPGSQAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHDMKKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPFG 5a2y A 2.75 BS01 UTP A 1 F224 S226 N229 D239 C330 N371 F372 F173 S175 N178 D188 C271 N312 F313 F1NBW0 26319014 KTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKAAEHHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHDKKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a2y B 2.75 BS01 UTP B 1 F224 G225 S226 D239 A327 C330 N371 F169 G170 S171 D184 A264 C267 N308 F1NBW0 26319014 KTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKHHVVPYKSRLFTFTLKNPGSQAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHDKKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a2z A 2.45 BS01 GTP A 1 S226 D239 N371 S175 D188 N310 F1NBW0 26319014 KTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKAAEHHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a2z B 2.45 BS01 GTP B 1 F224 G225 S226 D239 N371 F372 N472 F169 G170 S171 D184 N306 F307 N407 F1NBW0 26319014 KTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a30 A 2.75 BS01 MG A 1 S226 D239 S172 D185 F1NBW0 26319014 KKTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWDPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a30 A 2.75 BS02 AGS A 1 F224 G225 S226 D239 A327 N371 F372 D472 I480 F170 G171 S172 D185 A263 N307 F308 D408 I416 F1NBW0 26319014 KKTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWDPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5a30 B 2.75 BS01 AGS B 1 F224 S226 D237 D239 A327 N371 F372 I480 F170 S172 D183 D185 A264 N308 F309 I417 F1NBW0 26319014 KKTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENRGIHALIEFSEKSSVASLQAVTGIPKHVVPYKSRLFTFTLKNPGSQAAEERPVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLACSLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHKKGPFEMEYQMKRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTGFQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVPGTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPESSPLYIWDPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINKEPWGLAAVLIPF 5abj A 2.75 BS01 YM2 A 1 I111 L113 M114 F135 F137 Y155 P177 V179 M195 Y201 Q202 W203 N228 M230 I100 L102 M103 F124 F126 Y144 P166 V168 M184 Y190 Q191 W192 N217 M219 I3W9E1 DPIADMISLTALQVLPTAANTEASSHRLGTGVVPALQAAETGASSNASDKNLIETRCVLNHHSTQETAIGNFFSRAGLVSIITMPTTGTQNTDGYVNWDIDLMGYAQLRRKCELFTYMRFDAEFTFVVAKPNGELVPQLLQYMYVPPGAPKPTSRDSFAWQTATNPSVFVKMTDPPAQVSVPFMSPASAYQWFYDGYPTFGEHLQANDLDYGQCPNNMMGTFSIRTVGTEKSPHSITLRVYMRIKHVRAWIPRPLRNQPYLFKTNPNYKGNDIKCTSTSRDKITTL 5ae1 A 2.10 BS01 B2Z A 1 H189 D303 I511 M514 R515 G525 E526 S527 Y578 A582 H616 H617 H94 D208 I413 M416 R417 G427 E428 S429 Y480 A484 H518 H519 2.5.1.26 P97275 26322624 GIIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGLKKFYIKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5ae1 C 2.10 BS01 B2Z C 1 H189 V241 D303 I511 R515 G525 E526 S527 Y578 F581 A582 H616 H617 H109 V161 D223 I412 R416 G426 E427 S428 Y479 F482 A483 H517 H518 2.5.1.26 P97275 26322624 GIIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLDHKTTSKASLNPSDTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5ae2 A 2.00 BS01 FYC A 1 D303 I511 A512 R515 G525 E526 S527 Y578 Y580 A582 H616 H617 D214 I414 A415 R418 G428 E429 S430 Y481 Y483 A485 H519 H520 P97275 26322624 GIIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLDHKTDTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGLKKFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5ae3 A 2.18 BS01 AWB A 1 F128 I132 F136 R419 M421 Q425 F428 T467 G504 I511 M514 G518 L562 R566 Y580 F45 I49 F53 R325 M327 Q331 F334 T349 G386 I393 M396 G400 L443 R447 Y461 2.5.1.26 P97275 26322624 PKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLDHKTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5ae3 B 2.18 BS01 AWB B 1 F128 W131 I132 F136 R419 M421 Q425 F428 G429 T467 G504 I511 M514 R515 G518 G525 E526 R566 Y580 F47 W50 I51 F55 R324 M326 Q330 F333 G334 T348 G385 I392 M395 R396 G399 G406 E407 R447 Y461 2.5.1.26 P97275 26322624 IIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5ae3 C 2.18 BS01 AWB C 1 W131 F136 M421 Q425 F428 R503 G504 Y505 L506 L507 I511 M514 G518 I523 G525 E526 R566 Y580 W48 F53 M338 Q342 F345 R396 G397 Y398 L399 L400 I404 M407 G411 I416 G418 E419 R459 Y473 2.5.1.26 P97275 26322624 PKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLDHKTTSKASLNPSDTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5ae3 D 2.18 BS01 AWB D 1 W131 F136 M421 Q425 F428 G429 G504 Y505 L506 L507 I511 M514 G518 I523 E526 S527 L562 R566 Y580 W48 F53 M338 Q342 F345 G346 G393 Y394 L395 L396 I400 M403 G407 I412 E415 S416 L451 R455 Y469 2.5.1.26 P97275 26322624 PKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLDHKTTSKASLNPSDTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHAPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5aec A 1.93 BS01 PIN A 1 A111 Y112 P113 F203 I223 F292 M294 A110 Y111 P112 F191 I211 F280 M282 1.14.13.- D7UER1 AMETGLIFHPYMRPGRSARQTFDWGIKSAVQADSVGIDSMMISEHASQIWENIPNPELLIAAAALQTKNIKFAPMAHLLPHQHPAKLATMIGWLSQILEGRYFLGIGAGAYPQASYMHGIRNAGQSEETKNLNDMVRESLFIMEKIWKREPFFHEGKYWDAGYPEELEEQHKLADFSPWGGKAPEIAVTGFSYNSPSMRLAGERNFKPVSIFSGLDALKRHWEVYSEAAIEAGHTPDRSRHAVSHTVFCADTDKEAKRLVMEGPIGYCFERYLIPIWRRFGMMDGYAKDAGIDPVDADLEFLVDNVFLVGSPDTVTEKINALFEATGGWGTLQVEAHDYYDDPAPWFQSLELISKEVAPKILLP 5aec B 1.93 BS01 PIN B 1 A111 Y112 P113 F203 I223 F292 A110 Y111 P112 F189 I209 F278 1.14.13.- D7UER1 AMETGLIFHPYMRPGRSARQTFDWGIKSAVQADSVGIDSMMISEHASQIWENIPNPELLIAAAALQTKNIKFAPMAHLLPHQHPAKLATMIGWLSQILEGRYFLGIGAGAYPQASYMHGIRNAGQTKNLNDMVRESLFIMEKIWKREPFFHEGKYWDAGYPEELEDEQHKLADFSPWGGKAPEIAVTGFSYNSPSMRLAGERNFKPVSIFSGLDALKRHWEVYSEAAIEAGHTPDRSRHAVSHTVFCADTDKEAKRLVMEGPIGYCFERYLIPIWRRFGMMDGYAKDAGIDPVDADLEFLVDNVFLVGSPDTVTEKINALFEATGGWGTLQVEAHDYYDDPAPWFQSLELISKEVAPKILLPKR 5agf A 1.09 BS01 HEM A 1 R12 Q13 L16 T17 M19 A20 W56 F59 D67 I72 F79 Q83 F86 C116 C119 Y123 R124 R12 Q13 L16 T17 M19 A20 W56 F59 D67 I72 F79 Q83 F86 C116 C119 Y123 R124 P00138 26100643 EFAKPEDAVKYRQSALTLMASHFGRMTPVVKGQAPYDAAQIKANVEVLKTLSALPWAAFGPGTEGGDARPEIWSDAASFKQKQQAFQDNIVKLSAAADAGDLDKLRAAFGDVGASCKACHQAYRK 5agw A 2.70 BS01 III D 1 F104 Y108 D111 E114 M115 Q118 T132 V133 E136 L137 N143 G145 R146 F153 L201 Y202 F39 Y43 D46 E49 M50 Q53 T67 V68 E71 L72 N78 G80 R81 F88 L136 Y137 P10415 26317395 GYDNREIVMKYIHYKLSQRGYEWDSEVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGP 5agw B 2.70 BS01 III C 1 F104 R107 Y108 D111 F112 E114 M115 Q118 R129 T132 V133 E136 L137 N143 G145 R146 A149 F37 R40 Y41 D44 F45 E47 M48 Q51 R62 T65 V66 E69 L70 N76 G78 R79 A82 P10415 26317395 DNREIVMKYIHYKLSQRGYEWDSEVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGP 5agx A 2.24 BS01 III D 1 A100 D103 F104 R107 Y108 F112 M115 Q118 L119 T132 V133 E136 L137 R139 N143 W144 G145 R146 F153 L201 Y202 A36 D39 F40 R43 Y44 F48 M51 Q54 L55 T68 V69 E72 L73 R75 N79 W80 G81 R82 F89 L137 Y138 P10415 26317395 GYDNREIVMKYIHYKLSQRGYEWDASEVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGP 5agx B 2.24 BS01 III C 1 A100 F104 R107 Y108 D111 F112 M115 Q118 R129 V133 E136 L137 N143 W144 G145 R146 F153 L201 Y202 A37 F41 R44 Y45 D48 F49 M52 Q55 R66 V70 E73 L74 N80 W81 G82 R83 F90 L138 Y139 P10415 26317395 GYDNREIVMKYIHYKLSQRGYEWDAESEVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIAIWMTEYLNRHLHTWIQDNGGWDAFVELYGP 5awp A 2.00 BS01 BGC A 1 Y40 D77 D197 F198 V242 R261 D265 Y30 D67 D187 F188 V232 R251 D255 Q7WSN5 PVTAAPPLRLASRNSVFTRSGAGPRYWNIYGYSFPHNAPIPENEWKVNIDWLAGNFADFGYDIACTDGWIEGSSRTTGNGYITSYNDSWQHDWAYWANYLAARKMKLGVYYNPLWVHRAAVEDASKTVLGRPDVKIADLVVPGDFFARDIGGNQLYWLDVTKSGAKEYVQGYVRYFKDLGVPYLRIDFLSWYEDGRDANIGQVNAPHGRANYELALSWINEAAGEDMEVSLVMPHMFQDGSAELANGDLVRINADADKGGWDRLSGMRQNWQDAWPNWANPFCGFTGWSHRNGRGQLILDGDFMRASTFASDEERKTMMNLMVAAGSPLAIADTYQQIGNNAWVYTNKEVLQLNADGLVGKPLYRSATPFSKDPGSRDTERWAGQLPDGSWGVALFNRSDTETVTKTIDFAKDLGLATGGNVRDLWEHRNLGMDSRATAALAPHASAIFRVTPPKMHGTTRYPAAFAAWGGGAGFNYNHPGYDGNGFVDGLQAGSGSADPLVTFAVQVPHRGSYAIRYRYANATGDTSTMTVTAEKADRSTVDGPVHVSFPGLATWDTWGVADGTITLDAGLNLVTIGRGATDKGAINLNWIELDM 5awp A 2.00 BS02 GLC A 1 G78 W79 I80 E81 F156 F198 G68 W69 I70 E71 F146 F188 Q7WSN5 PVTAAPPLRLASRNSVFTRSGAGPRYWNIYGYSFPHNAPIPENEWKVNIDWLAGNFADFGYDIACTDGWIEGSSRTTGNGYITSYNDSWQHDWAYWANYLAARKMKLGVYYNPLWVHRAAVEDASKTVLGRPDVKIADLVVPGDFFARDIGGNQLYWLDVTKSGAKEYVQGYVRYFKDLGVPYLRIDFLSWYEDGRDANIGQVNAPHGRANYELALSWINEAAGEDMEVSLVMPHMFQDGSAELANGDLVRINADADKGGWDRLSGMRQNWQDAWPNWANPFCGFTGWSHRNGRGQLILDGDFMRASTFASDEERKTMMNLMVAAGSPLAIADTYQQIGNNAWVYTNKEVLQLNADGLVGKPLYRSATPFSKDPGSRDTERWAGQLPDGSWGVALFNRSDTETVTKTIDFAKDLGLATGGNVRDLWEHRNLGMDSRATAALAPHASAIFRVTPPKMHGTTRYPAAFAAWGGGAGFNYNHPGYDGNGFVDGLQAGSGSADPLVTFAVQVPHRGSYAIRYRYANATGDTSTMTVTAEKADRSTVDGPVHVSFPGLATWDTWGVADGTITLDAGLNLVTIGRGATDKGAINLNWIELDM 5awp A 2.00 BS03 GLC A 2 H489 Q502 W566 A596 N598 H479 Q492 W556 A586 N588 Q7WSN5 PVTAAPPLRLASRNSVFTRSGAGPRYWNIYGYSFPHNAPIPENEWKVNIDWLAGNFADFGYDIACTDGWIEGSSRTTGNGYITSYNDSWQHDWAYWANYLAARKMKLGVYYNPLWVHRAAVEDASKTVLGRPDVKIADLVVPGDFFARDIGGNQLYWLDVTKSGAKEYVQGYVRYFKDLGVPYLRIDFLSWYEDGRDANIGQVNAPHGRANYELALSWINEAAGEDMEVSLVMPHMFQDGSAELANGDLVRINADADKGGWDRLSGMRQNWQDAWPNWANPFCGFTGWSHRNGRGQLILDGDFMRASTFASDEERKTMMNLMVAAGSPLAIADTYQQIGNNAWVYTNKEVLQLNADGLVGKPLYRSATPFSKDPGSRDTERWAGQLPDGSWGVALFNRSDTETVTKTIDFAKDLGLATGGNVRDLWEHRNLGMDSRATAALAPHASAIFRVTPPKMHGTTRYPAAFAAWGGGAGFNYNHPGYDGNGFVDGLQAGSGSADPLVTFAVQVPHRGSYAIRYRYANATGDTSTMTVTAEKADRSTVDGPVHVSFPGLATWDTWGVADGTITLDAGLNLVTIGRGATDKGAINLNWIELDM 5awq A 1.48 BS01 GLC A 1 D207 M243 D265 W285 D197 M233 D255 W275 Q7WSN5 PVTAAPPLRLASRNSVFTRSGAGPRYWNIYGYSFPHNAPIPENEWKVNIDWLAGNFADFGYDIACTDGWIEGSSRTTGNGYITSYNDSWQHDWAYWANYLAARKMKLGVYYNPLWVHRAAVEDASKTVLGRPDVKIADLVVPGDFFARDIGGNQLYWLDVTKSGAKEYVQGYVRYFKDLGVPYLRIDFLSWYEDGRDANIGQVNAPHGRANYELALSWINEAAGEDMEVSLVMPHMFQDGSAELANGDLVRINADADKGGWDRLSGMRQNWQDAWPNWANPFCGFTGWSHRNGRGQLILDGDFMRASTFASDEERKTMMNLMVAAGSPLAIADTYQQIGNNAWVYTNKEVLQLNADGLVGKPLYRSATPFSKDPGSRDTERWAGQLPDGSWGVALFNRSDTETVTKTIDFAKDLGLATGGNVRDLWEHRNLGMDSRATAALAPHASAIFRVTPPKMHGTTRYPAAFAAWGGGAGFNYNHPGYDGNGFVDGLQAGSGSADPLVTFAVQVPHRGSYAIRYRYANATGDTSTMTVTAEKADRSTVDGPVHVSFPGLATWDTWGVADGTITLDAGLNLVTIGRGATDKGAINLNWIELDM 5awq A 1.48 BS02 GLC A 2 Y40 D77 D197 F198 R261 D265 Y30 D67 D187 F188 R251 D255 Q7WSN5 PVTAAPPLRLASRNSVFTRSGAGPRYWNIYGYSFPHNAPIPENEWKVNIDWLAGNFADFGYDIACTDGWIEGSSRTTGNGYITSYNDSWQHDWAYWANYLAARKMKLGVYYNPLWVHRAAVEDASKTVLGRPDVKIADLVVPGDFFARDIGGNQLYWLDVTKSGAKEYVQGYVRYFKDLGVPYLRIDFLSWYEDGRDANIGQVNAPHGRANYELALSWINEAAGEDMEVSLVMPHMFQDGSAELANGDLVRINADADKGGWDRLSGMRQNWQDAWPNWANPFCGFTGWSHRNGRGQLILDGDFMRASTFASDEERKTMMNLMVAAGSPLAIADTYQQIGNNAWVYTNKEVLQLNADGLVGKPLYRSATPFSKDPGSRDTERWAGQLPDGSWGVALFNRSDTETVTKTIDFAKDLGLATGGNVRDLWEHRNLGMDSRATAALAPHASAIFRVTPPKMHGTTRYPAAFAAWGGGAGFNYNHPGYDGNGFVDGLQAGSGSADPLVTFAVQVPHRGSYAIRYRYANATGDTSTMTVTAEKADRSTVDGPVHVSFPGLATWDTWGVADGTITLDAGLNLVTIGRGATDKGAINLNWIELDM 5bsx A 1.78 BS01 FLC A 1 N342 A354 N355 R356 D385 N118 A124 N125 R126 D155 Q5F4T5 26295280 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 5bvd A 1.90 BS01 4VF A 1 I29 E31 G32 Y34 G35 M36 V37 A50 K52 I54 D104 M106 E107 T108 D109 K112 N152 L154 D165 I23 E25 G26 Y28 G29 M30 V31 A44 K46 I48 D98 M100 E101 T102 D103 K106 N146 L148 D159 2.7.11.24 P28482 26259804 AGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTRWYRAPEIMLNTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY 5bve A 2.00 BS01 4VG A 1 E31 G32 Y34 G35 M36 V37 A50 K52 K53 D104 M106 E107 T108 D109 K112 N152 L154 C164 D165 E25 G26 Y28 G29 M30 V31 A44 K46 K47 D98 M100 E101 T102 D103 K106 N146 L148 C158 D159 2.7.11.24 P28482 26259804 AGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTRWYRAPEIMLNTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY 5bvf A 1.90 BS01 4VJ A 1 I29 G32 Y34 G35 M36 V37 A50 K52 K53 D104 M106 T108 D109 K112 N152 L154 C164 D165 I23 G26 Y28 G29 M30 V31 A44 K46 K47 D98 M100 T102 D103 K106 N146 L148 C158 D159 2.7.11.24 P28482 26259804 AGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVRWYRAPEIMTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY 5bwb A 2.57 BS01 4VV A 1 Y70 D72 S81 Y121 E278 W279 F330 F331 Y334 Y67 D69 S78 Y118 E275 W276 F327 F328 Y331 3.1.1.7 P04058 SELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 5bwc A 2.45 BS01 HBP A 1 Y70 W84 G119 Y121 W279 F290 F330 Y334 G335 Y67 W81 G116 Y118 W276 F287 F327 Y331 G332 3.1.1.7 P04058 SELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 5bxp A 1.70 BS01 GAL A 1 C187 C189 Q190 E216 N259 H263 D320 P466 D467 C160 C162 Q163 E189 N232 H236 D293 P439 D440 3.2.1.140 B3TLD6 26312778 HHSSGLVPRGSHMGYSATAPVNLTRPATVPSMDGWTDGTGAWTLGEGTRVVSSDALAARAQSLASELTKFTDVDIKAATGSATGKDISLTLDASKKAELGDEGFKLNIGSKGLEVIGATDIGVFYGTRSVSQMLRQGQLTLPAGTVATKPKYKERGATLCACQINISTDWIDRFLSDMADLRLNYVLLEMKLKPEEDNTKKAATWSYYTRDDVKKFVKKANNYGIDVIPEINSPGHMNVWLENYPEYQLADNSGRKDPNKLDISNPEAVKFYKTLIDEYDGVFTTKYWHMGADEYMIGTSFDNYSKLKTFAEKQYGAGATPNDAFTGFINDIDKYVKAKGKQLRIWNDGIVNTKNVSLNKDIVIEYWYGAGRKPQELVQDGYTLMNATQALYWSRSAQVYKVNAARLYNNNWNVGTFDGGRQIDKNYDKLTGAKVSIWPDSSYFQTENEVEKEIFDGMRFISQMTWSDSRPWATWNDMKADIDKIGYPLDIREYDYTPVDAGIYDIPQLKSISKGPWELITTPDGYYQMKDTVSGKCLALFTGSKHLDVVTQVGARPELRNCADVSVGQDQRNTANERNTQKWQIRADKDGKYTISPALTQQRLAIATGNEQNIDLETHRPAAGTVAQFPADLVSD 5bxp A 1.70 BS02 LOG A 1 D320 E321 W394 Y419 Y427 W465 D467 D293 E294 W367 Y392 Y400 W438 D440 3.2.1.140 B3TLD6 26312778 HHSSGLVPRGSHMGYSATAPVNLTRPATVPSMDGWTDGTGAWTLGEGTRVVSSDALAARAQSLASELTKFTDVDIKAATGSATGKDISLTLDASKKAELGDEGFKLNIGSKGLEVIGATDIGVFYGTRSVSQMLRQGQLTLPAGTVATKPKYKERGATLCACQINISTDWIDRFLSDMADLRLNYVLLEMKLKPEEDNTKKAATWSYYTRDDVKKFVKKANNYGIDVIPEINSPGHMNVWLENYPEYQLADNSGRKDPNKLDISNPEAVKFYKTLIDEYDGVFTTKYWHMGADEYMIGTSFDNYSKLKTFAEKQYGAGATPNDAFTGFINDIDKYVKAKGKQLRIWNDGIVNTKNVSLNKDIVIEYWYGAGRKPQELVQDGYTLMNATQALYWSRSAQVYKVNAARLYNNNWNVGTFDGGRQIDKNYDKLTGAKVSIWPDSSYFQTENEVEKEIFDGMRFISQMTWSDSRPWATWNDMKADIDKIGYPLDIREYDYTPVDAGIYDIPQLKSISKGPWELITTPDGYYQMKDTVSGKCLALFTGSKHLDVVTQVGARPELRNCADVSVGQDQRNTANERNTQKWQIRADKDGKYTISPALTQQRLAIATGNEQNIDLETHRPAAGTVAQFPADLVSD 5bxs A 2.20 BS01 GAL A 1 C187 C189 Q190 E216 N259 H263 D320 W465 P466 D467 L574 C158 C160 Q161 E187 N230 H234 D291 W436 P437 D438 L545 3.2.1.140 B3TLD6 26312778 SSGLVPRGSHMGYSATAPVNLTRPATVPSMDGWTDGTGAWTLGEGTRVVSSDALAARAQSLASELTKFTDVDIKAATGSATGKDISLTLDASKKAELGDEGFKLNIGSKGLEVIGATDIGVFYGTRSVSQMLRQGQLTLPAGTVATKPKYKERGATLCACQINISTDWIDRFLSDMADLRLNYVLLEMKLKPEEDNTKKAATWSYYTRDDVKKFVKKANNYGIDVIPEINSPGHMNVWLENYPEYQLADNSGRKDPNKLDISNPEAVKFYKTLIDEYDGVFTTKYWHMGADEYMIGTSFDNYSKLKTFAEKQYGAGATPNDAFTGFINDIDKYVKAKGKQLRIWNDGIVNTKNVSLNKDIVIEYWYGAGRKPQELVQDGYTLMNATQALYWSRSAQVYKVNAARLYNNNWNVGTFDGGRQIDKNYDKLTGAKVSIWPDSSYFQTENEVEKEIFDGMRFISQMTWSDSRPWATWNDMKADIDKIGYPLDIREYDYTPVDAGIYDIPQLKSISKGPWELITTPDGYYQMKDTVSGKCLALFTGSKHLDVVTQVGARPELRNCADVSVGQDQRNTANERNTQKWQIRADKDGKYTISPALTQQRLAIATGNEQNIDLETHRPAAGTVAQFPADLVS 5c6d A 2.29 BS01 III C 1 Q626 A627 R628 S629 N630 E736 E744 D758 E759 M761 D764 Q66 A67 R68 S69 N70 E166 E174 D188 E189 M191 D194 3.4.19.12 Q93009 26299963 AHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLADGNKTMIELSDNENPWTIFLETVDPTLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQL 5ccl A 1.50 BS05 4ZW A 1 N181 S182 F183 T184 E192 S202 I237 Y239 Y257 N179 S180 F181 T182 E190 S200 I235 Y237 Y255 2.1.1.43 Q9H7B4 PLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRA 5ccl A 1.50 BS06 4ZW A 2 R19 V21 V231 G232 R17 V19 V229 G230 2.1.1.43 Q9H7B4 PLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRA 5ccm A 2.30 BS04 SAM A 1 R14 G15 N16 Y124 N132 N181 S202 L203 L204 N205 H206 Y239 Y257 F259 R12 G13 N14 Y122 N130 N179 S200 L201 L202 N203 H204 Y237 Y255 F257 2.1.1.43 Q9H7B4 PLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANI 5ccm A 2.30 BS05 4ZX A 1 N181 S182 F183 T184 C186 M190 E192 S202 I214 I237 C238 Y239 L240 D241 Y257 E294 K329 D332 C333 V368 N179 S180 F181 T182 C184 M188 E190 S200 I212 I235 C236 Y237 L238 D239 Y255 E292 K327 D330 C331 V366 2.1.1.43 Q9H7B4 PLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANI 5cg8 A 2.70 BS01 NUC B 1 S148 M149 P150 N232 K303 K318 S93 M94 P95 N177 K248 K263 D2W6T1 MINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYYEDTQKNSLKIHKETK 5cg8 A 2.70 BS02 NUC C 1 Y141 L145 N147 M149 Y153 T155 A156 A212 R224 D234 V293 F295 H297 Q310 K311 Y86 L90 N92 M94 Y98 T100 A101 A157 R169 D179 V238 F240 H242 Q255 K256 D2W6T1 MINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYYEDTQKNSLKIHKETK 5cg8 A 2.70 BS03 AKG A 1 N214 R224 H229 D231 L240 Y242 L253 H279 V281 R289 V293 N159 R169 H174 D176 L185 Y187 L198 H224 V226 R234 V238 D2W6T1 MINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYYEDTQKNSLKIHKETK 5cg9 D 2.69 BS01 NUC E 1 S148 M149 P150 N232 K303 S92 M93 P94 N176 K247 D2W6T1 INKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYYEDTQKNSLKIHKET 5cg9 D 2.69 BS02 NUC F 1 Y141 N147 Y153 T155 A156 A212 R224 D234 V293 F295 H297 Q310 Y85 N91 Y97 T99 A100 A156 R168 D178 V237 F239 H241 Q254 D2W6T1 INKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYYEDTQKNSLKIHKET 5ch9 A 1.90 BS02 CO A 2 H23 K145 H178 H206 R230 H21 K143 H176 H204 R228 3.5.-.- Q5KZU5 EMVETVCGPVPVEQLGKTLIHEHFLFGYPGFQGDVTRGTFREDESLRVAVEAAEKMKRHGIQTVVDPTPNDCGRNPAFLRRVAEETGLNIICATGYYYEGEGAPPYFQFRRLLGTAEDDIYDMFMAELTEGIADTGIKAGVIKLASSKGRITEYEKMFFRAAARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADPKKIVIGHMCGNTDPDYHRKTLAYGVYIAFDRFGIQDRGMVGMIAPTDEERVRTLLALLRDGYEKQIMLSHDTVNVWLGRPFTLPEPFAEMMKNWHVEHLFVNIIPALKNEGIRDEVLEQMFIGNPAALFSA 5ch9 B 1.90 BS01 CO B 1 H23 K145 H178 H206 H21 K143 H176 H204 3.5.-.- Q5KZU5 EMVETVCGPVPVEQLGKTLIHEHFLFGYPGFQGDVTRGTFREDESLRVAVEAAEKMKRHGIQTVVDPTPNDCGRNPAFLRRVAEETGLNIICATGYYYEGEGAPPYFQFRRLLGTAEDDIYDMFMAELTEGIADTGIKAGVIKLASSKGRITEYEKMFFRAAARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADPKKIVIGHMCGNTDPDYHRKTLAYGVYIAFDRFGIQDRGMVGMIAPTDEERVRTLLALLRDGYEKQIMLSHDTVNVWLGRPFTLPEPFAEMMKNWHVEHLFVNIIPALKNEGIRDEVLEQMFIGNPAALFSA 5cit A 1.75 BS01 GDP A 1 G19 G20 T21 G22 K23 T24 T25 K71 N122 K123 D125 I126 S150 A151 K152 G12 G13 T14 G15 K16 T17 T18 K64 N115 K116 D118 I119 S143 A144 K145 P62826 26272610 QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQT 5cjt A 3.40 BS02 CO6 A 1 F585 F587 R589 R596 F598 R622 S624 S677 T679 R728 T730 Q732 Q742 Y772 Y779 H780 S821 F823 R856 K861 H863 Q865 S897 F556 F558 R560 R567 F569 R593 S595 S648 T650 R699 T701 Q703 Q713 Y743 Y750 H751 S792 F794 R827 K832 H834 Q836 S868 5.4.99.2 Q1LRY0 RGPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREASEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGEDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDEAITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGDPQTLELARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5cjt B 3.40 BS01 B12 B 1 H39 D40 A41 S42 I43 M46 A82 Y86 Q87 G114 G116 V118 Y136 S137 P138 G141 M149 M153 G741 Q742 H780 H18 D19 A20 S21 I22 M25 A61 Y65 Q66 G93 G95 V97 Y115 S116 P117 G120 M128 M132 G719 Q720 H758 5.4.99.2 Q1LRY0 GPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVVKIRDKEIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGLARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5cjt B 3.40 BS02 CO6 B 1 F585 F587 R589 R856 F564 F566 R568 R834 5.4.99.2 Q1LRY0 GPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVVKIRDKEIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGLARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM 5ck3 B 3.20 BS01 MG B 1 T64 H105 T106 S107 T14 H55 T56 S57 G0S401 26299945 PSVLLIGPSGAGKTALLTLFERGPLLNPDGTSVGAADLKNPYRKPIVTSPVAQTHTSQVPTSVELAVGANEDGTPTSYKVDLDATARKFLLIDTPGHPKLRGTTLQHLLNPSPSLTIIPTNAPNKSHSDPYKSKLKAVIFLLDAAALADSDGDYLSQTASYLYDVLLSLQKRFHSRKNRAPSSIPVLIAANKQDLFTAVPASLVKSRLEHELGRIRKTRQKGGWLGAVGSKEFKFEEMMEFDMEVEVMGGNVIGDGPGAERWWRWIGERI 5ck3 B 3.20 BS02 GTP B 1 S59 G60 A61 G62 K63 T64 A65 T104 T106 S107 G149 N250 K251 D253 L254 N328 V329 I330 S9 G10 A11 G12 K13 T14 A15 T54 T56 S57 G96 N191 K192 D194 L195 N251 V252 I253 G0S401 26299945 PSVLLIGPSGAGKTALLTLFERGPLLNPDGTSVGAADLKNPYRKPIVTSPVAQTHTSQVPTSVELAVGANEDGTPTSYKVDLDATARKFLLIDTPGHPKLRGTTLQHLLNPSPSLTIIPTNAPNKSHSDPYKSKLKAVIFLLDAAALADSDGDYLSQTASYLYDVLLSLQKRFHSRKNRAPSSIPVLIAANKQDLFTAVPASLVKSRLEHELGRIRKTRQKGGWLGAVGSKEFKFEEMMEFDMEVEVMGGNVIGDGPGAERWWRWIGERI 5ck3 D 3.20 BS01 MG D 1 T64 S107 D146 T147 T18 S56 D87 T88 G0S401 26299945 YTTLPSVLLIGPSGAGKTALLTLFERGPLLNPDGTSLKNPYRKPIVTSPVAQTHTSQVPTSVELAVGANEPTSYKVDLTARKFLLIDTPGHPKLRGTTLQHLLNPSPPYKSKLKAVIFLLDAAALADSDGDYLSQTASYLYDVLLSLQKRFHSSIPVLIAANKQDLFTAVPASLVKSRLEHELGRIRKTRQKFKFEEMMEFDMEVEVMGGNVIGDGPGAERWWRWIGERI 5ck3 D 3.20 BS02 GTP D 1 S59 G60 A61 G62 K63 T64 A65 T104 T106 S107 P148 G149 N250 K251 D253 N328 V329 I330 S13 G14 A15 G16 K17 T18 A19 T53 T55 S56 P89 G90 N162 K163 D165 N211 V212 I213 G0S401 26299945 YTTLPSVLLIGPSGAGKTALLTLFERGPLLNPDGTSLKNPYRKPIVTSPVAQTHTSQVPTSVELAVGANEPTSYKVDLTARKFLLIDTPGHPKLRGTTLQHLLNPSPPYKSKLKAVIFLLDAAALADSDGDYLSQTASYLYDVLLSLQKRFHSSIPVLIAANKQDLFTAVPASLVKSRLEHELGRIRKTRQKFKFEEMMEFDMEVEVMGGNVIGDGPGAERWWRWIGERI 5ck3 F 3.20 BS01 MG F 1 K63 T64 S107 D146 T147 K10 T11 S35 D45 T46 G0S401 26299945 LLIGPSGAGKTALLTLFERGPKPIVTSPVAQTHTSQVPTSVLLIDTPGHPKLRGTTLQHVIFLLDAAALADSSQTASYLYDVLLSLQKRFPVLIAANKQDLFTAVPASLVKSRLEHELGRIRKVEVMGGNVDGPGAERWWRWIGERI 5ck3 F 3.20 BS02 GTP F 1 P58 S59 G60 A61 G62 K63 T64 A65 T104 H105 T106 S107 T147 P148 G149 N250 K251 D253 N328 V329 P5 S6 G7 A8 G9 K10 T11 A12 T32 H33 T34 S35 T46 P47 G48 N97 K98 D100 N130 V131 G0S401 26299945 LLIGPSGAGKTALLTLFERGPKPIVTSPVAQTHTSQVPTSVLLIDTPGHPKLRGTTLQHVIFLLDAAALADSSQTASYLYDVLLSLQKRFPVLIAANKQDLFTAVPASLVKSRLEHELGRIRKVEVMGGNVDGPGAERWWRWIGERI 5ck4 A 1.89 BS01 GDP A 1 S59 G60 A61 G62 K63 T64 A65 N250 K251 D253 L254 N328 V329 I330 S12 G13 A14 G15 K16 T17 A18 N134 K135 D137 L138 N195 V196 I197 G0S401 26299945 TTLPSVLLIGPSGAGKTALLTLFERTSYKVDLDAAGATARKFLLIDTPGHPKLRGTTLQHLLNPSPSLTIIPYKSKLKAVIFLLDAAALADSDGDYLSQTASYLYDVLLSLQKRFHSRKNSRAPSSIPVLIAANKQDLFTAVPASLVKSRLEHELGRIRKTRQKGEGWLGAVGSKEFKFEEMMEFDMEVEVMGGNVIGDGPGAERWWRWIGERI 5ck5 D 2.40 BS01 GDP D 1 G60 G62 K63 T64 A65 N250 K251 D253 L254 N328 V329 I330 G11 G13 K14 T15 A16 N127 K128 D130 L131 N187 V188 I189 G0S401 26299945 LPSVLLIGPSGAGKTALLTLFERTSYKVDLDAAGATARKFLLIDTPGHPKLRGTTLQHLLNPSPSLTIIPTSKLKAVIFLLDAAALADSDGDYLSQTASYLYDVLLSLQKRFHSRAPSSIPVLIAANKQDLFTAVPASLVKSRLEHELGRIRKTRQKGLWLGAVGSKEFKFEEMMEFDMEVEVMGGNVIGDGPGAERWWRWIGERI 5cll A 2.45 BS01 GDP A 1 G19 G20 T21 G22 K23 T24 T25 F35 E36 K37 K38 Y39 N122 K123 D125 I126 S150 A151 K152 G12 G13 T14 G15 K16 T17 T18 F28 E29 K30 K31 Y32 N115 K116 D118 I119 S143 A144 K145 P62826 26272610 QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPE 5cll A 2.45 BS02 BEF A 1 G19 K23 T24 Y39 A41 T42 A67 G68 Q69 G12 K16 T17 Y32 A34 T35 A60 G61 Q62 P62826 26272610 QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPE 5cll C 2.45 BS02 BEF C 1 G19 K23 Y39 A41 T42 A67 G68 Q69 G12 K16 Y32 A34 T35 A60 G61 Q62 P62826 26272610 QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPE 5clq A 3.20 BS01 GNP A 1 G19 G20 T21 G22 K23 T24 T25 F35 E36 K37 K38 A39 A41 T42 A67 G68 N122 K123 D125 I126 S150 A151 K152 G15 G16 T17 G18 K19 T20 T21 F31 E32 K33 K34 A35 A37 T38 A63 G64 N118 K119 D121 I122 S146 A147 K148 P62826 26272610 GEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKAVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPD 5cnj A 2.65 BS01 52Q A 1 R57 R61 S143 Y144 S145 A166 S167 T168 Y216 R271 S272 E273 D295 G296 K377 R36 R40 S100 Y101 S102 A123 S124 T125 Y173 R228 S229 E230 D252 G253 K334 Q14416 26313429 AKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNISVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWA 5cnk A 3.15 BS01 GGL A 1 R64 R68 S149 Y150 S151 A172 T174 Y222 D301 K389 R35 R39 S100 Y101 S102 A123 T125 Y173 D252 K334 Q14832 26313429 RREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNISIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAASRANASFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSLQRVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLKINFTAPFNPDSIVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNSIHWSRNS 5cnm A 2.84 BS01 52Q A 1 R64 R68 Y150 S151 A172 S173 T174 K389 R35 R39 Y101 S102 A123 S124 T125 K334 Q14832 26313429 RREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNISIATAEKVGIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAASRANASFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSLQNHRRVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQSYLKVGHWAETLSLDVN 5cnm A 2.84 BS02 MG A 1 I79 D82 L85 L86 I50 D53 L56 L57 Q14832 26313429 RREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNISIATAEKVGIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAASRANASFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSLQNHRRVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQSYLKVGHWAETLSLDVN 5cq4 A 1.78 BS01 53C A 1 P1888 N1944 I1950 P33 N89 I95 Q9UIF8 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFK 5cq5 A 1.96 BS01 53E A 1 E1945 D1946 E90 D91 Q9UIF8 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTF 5cq5 A 1.96 BS02 53E A 2 E1927 W1965 F1969 E72 W110 F114 Q9UIF8 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTF 5cq6 A 1.97 BS01 PDC A 1 K1896 K1902 K41 K47 Q9UIF8 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFK 5cq7 A 1.86 BS01 53G A 1 P1888 V1898 F1943 N1944 P33 V43 F88 N89 Q9UIF8 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFK 5cq8 A 1.65 BS01 AC6 A 1 P1888 V1893 N1944 P33 V38 N89 Q9UIF8 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFK 5cq9 B 3.00 BS01 III D 1 L53 L56 Y90 L18 L21 Y43 Q8ZQC8 26299973 VWDRFKDCFRTHKKQEVLEVLYTLIHGCTGMEKIHAFTQLKEYANPSQQDRFVMRFDMNQTQVLFEIDGKVIDKCNLHRLLNVSENCIFKVMEEDEEELFLKICIKYGEKISRYPELLEGFANKLKDAVNEDDDVKDEVYKLMRSGEDRKMECVEWNGTLTEEEKNKLRCLQMGSFNITTQFFKIGYWELEGEVLFDMVHPTLSYLLQAYKPSLSLIETNTMLFSDVLNKDYDDYQNNKREIDAILRRIYRSHNNTLFISEKSSCRNMLI 5cqa A 2.13 BS01 2LY A 1 P1888 F1889 V1893 F1943 N1944 I1950 P33 F34 V38 F88 N89 I95 Q9UIF8 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFK 5cqg A 2.30 BS01 55C A 1 M482 M483 R486 F494 I550 Y551 G553 L554 R557 M482 M483 R486 F494 I550 Y551 G553 L554 R557 Q0QHL8 MVHYYRLSLKSRQKAPKIVNSKYNSILNIALKNFRLCKKHKTKKPVQILALLQEIIPKSYFGTTTNLKRFYKVVEKILTQSSFECIHLSVLHKCYDYDAIPWLQNVEPNLRPKLLLKHNLFLLDNIVKPIIAFYYKPIKTLNGHEIKFIRKEEYISFESKVFHKLKKMKYLVEVQDEVKPRGVLNIIPKQDNFRAIVSIFPDSARKPFFKLLTSKIYKVLEEKYKTSGSLYTCWSEFTQKTQGQIYGIKVDIRDAYGNVKIPVLCKLIQSIPTHLLDSEKKNFIVDHISNQFVAFRRKIYKWNHGLLQGDPLSGCLCELYMAFMDRLYFSNLDKDAFIHRTVDDYFFCSPHPHKVYDFELLIKGVYQVNPTKTRTNLPTHRHPQDEIPYCGKIFNLTTRQVRTLYKLPPNYEIRHKFKLWNFNNQISDDNPARFLQKAMDFPFICNSFTKFEFNTVFNDQRTVFANFYDAMICVAYKFDAAMMALRTSFLVNDFGFIWLVLSSTVRAYASRAFKKIVTYKGGKYRKVTFQCLKSIAWRAFLAVLKRRTEIYKGLIDRIKSREKLTMKFHDGEVDASYFCKLPEKFRFVKINRKASI 5cqu A 2.35 BS01 JRJ A 1 L45 G48 S51 V53 V66 I95 F113 E114 V116 M163 I174 D175 L44 G47 S50 V52 V65 I94 F112 E113 V115 M162 I173 D174 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5cqw A 2.65 BS01 JRJ A 1 L45 V53 V66 K68 I95 F113 E114 V116 D120 M163 I174 D175 L44 V52 V65 K67 I94 F112 E113 V115 D119 M162 I173 D174 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQA 5crw A 1.60 BS01 III B 1 I213 G214 P215 Y218 S219 M222 I262 A266 F267 A269 H270 I6 G7 P8 Y11 S12 M15 I55 A59 F60 A62 H63 5.3.4.1 P55059 PLIGEIGPETYSDYMSAGIPLAYIFAETAEERKELSDKLKPIAEAQRGVINFGTIDAKAFGAHAGNLNLKTDKFPAFAIQEVAKNQKFPFDQEKEITFEAIKAFVDDFVAGKIEPSIKSEPIPEKQEGPVTVVVAKNYNEIVLDDTKDVLIEFYAPWCGHCKALAPKYEELGALYAKSEFKDRVVIAKVDATANDVPDEIQGFPTIKLYPAGAKGQPVTYSGSRTVEDLIKFIAENGKYKAA 5ct7 A 3.17 BS01 55J A 1 I463 V471 A481 K483 E501 L505 I513 L514 I527 T529 Q530 W531 C532 G534 L567 H574 F583 I592 G593 D594 F595 I15 V23 A33 K35 E53 L57 I65 L66 I79 T81 Q82 W83 C84 G86 L119 H126 F135 I144 G145 D146 F147 2.7.11.1 P15056 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLAGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL 5cu8 A 2.05 BS02 54T A 2 L1891 P1892 L36 P37 Q9UIF8 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFK 5cuc A 1.85 BS01 54W A 1 P1888 V1893 N1944 I1950 P33 V38 N89 I95 Q9UIF8 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFK 5d11 A 2.30 BS01 56G A 1 L273 G274 A293 M338 E339 Y340 M341 S342 K343 G344 C345 L393 L16 G17 A36 M75 E76 Y77 M78 S79 K80 G81 C82 L130 2.7.10.2 P00523 26275028 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSEAQVMKKLRHEKLVQLYAVVSEEPIYIVMEYMSKGCLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 5d12 A 3.00 BS01 G97 A 1 L273 G274 V281 A293 M338 E339 Y340 M341 S342 G344 L393 L17 G18 V25 A37 M77 E78 Y79 M80 S81 G83 L132 2.7.10.2 P00523 26275028 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVMEYMSKGCLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 5d12 B 3.00 BS01 G97 B 1 L273 A293 M338 E339 Y340 M341 G344 L393 L16 A36 M74 E75 Y76 M77 G80 L129 2.7.10.2 P00523 26275028 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVMEYMSKGCLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 5d9i A 1.70 BS01 NUC Y 1 N153 R154 T155 R202 N25 R26 T27 R74 3.6.4.- P03070 20980496 GSKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPES 5d9i B 1.70 BS01 NUC Y 1 A149 S152 N153 R154 N227 A21 S24 N25 R26 N99 3.6.4.- P03070 20980496 GSKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPE 5d9i B 1.70 BS02 CA B 1 K167 A212 Q213 C216 L221 K39 A84 Q85 C88 L93 3.6.4.- P03070 20980496 GSKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPE 5da0 A 3.20 BS01 DMU A 1 F131 L236 V237 L240 E241 L244 V335 S338 T339 F118 L223 V224 L227 E228 L231 V322 S325 T326 Q1J2S8 QREWFANPRKDVLAGIVVALALIPEAIAFSIIAGVDPQVGLYASFIIALITAFLGGRPGMISAATGAMALLMTGLVKDHGIQYLFAATVLTGVLQVVFGWAKLARYLKFVPRSVMVGFVNALAILIFMAQLPQFVGANWQMYAMVAAGLAIIYLLPLVFKAMPSALVAIVVLTVVAVVTGADVKTVGDMGTLPTALPHFQFPQVPLTFETLAIIFPVALTLSLVGLLESLLTAQLIDERTDTTSDKNVESRGQGVANIVTGFFGGMAGCAMIGQSMINVTSGGRGRLSTFVAGAFLMVLILALQPLLVQIPMAALVAVMMVVAISTFDWGSLRFPKGETVVMLATVAVTVFTHDLSLGVLIGVVLSALFFARKVSQLSQVTPVDEVDGTRTYRVRGQLFFVSTHDFLHQFDFTHPARRVVIDLSDAHFWDGSAVGALDKVMLKFMRQGTSVELRGLNAASATLVERL 5da0 A 3.20 BS02 DMU A 2 R15 W17 R70 D254 T255 T256 R2 W4 R57 D241 T242 T243 Q1J2S8 QREWFANPRKDVLAGIVVALALIPEAIAFSIIAGVDPQVGLYASFIIALITAFLGGRPGMISAATGAMALLMTGLVKDHGIQYLFAATVLTGVLQVVFGWAKLARYLKFVPRSVMVGFVNALAILIFMAQLPQFVGANWQMYAMVAAGLAIIYLLPLVFKAMPSALVAIVVLTVVAVVTGADVKTVGDMGTLPTALPHFQFPQVPLTFETLAIIFPVALTLSLVGLLESLLTAQLIDERTDTTSDKNVESRGQGVANIVTGFFGGMAGCAMIGQSMINVTSGGRGRLSTFVAGAFLMVLILALQPLLVQIPMAALVAVMMVVAISTFDWGSLRFPKGETVVMLATVAVTVFTHDLSLGVLIGVVLSALFFARKVSQLSQVTPVDEVDGTRTYRVRGQLFFVSTHDFLHQFDFTHPARRVVIDLSDAHFWDGSAVGALDKVMLKFMRQGTSVELRGLNAASATLVERL 5dbe X 2.25 BS02 OAS X 1 M96 R100 M120 F144 G228 A231 M94 R98 M118 F139 G223 A226 2.5.1.47 P45040 MAIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGTLTKGKEIVDATNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAKGMKGAIKAEEIVDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDLSIIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSASERYLSTALF 5dbe X 2.25 BS03 P1T X 1 K42 T69 N72 T73 Q143 G177 T178 G179 S181 Q227 G228 I229 S272 P299 S300 Y305 K42 T69 N70 T71 Q138 G172 T173 G174 S176 Q222 G223 I224 S267 P294 S295 Y300 2.5.1.47 P45040 MAIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGTLTKGKEIVDATNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAKGMKGAIKAEEIVDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDLSIIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSASERYLSTALF 5dcs A 2.01 BS01 MN3 A 1 E69 E102 H105 E68 E101 H104 1.17.4.1 Q5KW80 26324712 VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDILPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGYVDYLTELGKRQQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRTKR 5dde A 1.78 BS02 5A0 A 2 S155 L177 S178 F238 C241 Y276 M278 N282 Y319 M322 Y323 S134 L156 S157 F217 C220 Y255 M257 N261 Y298 M301 Y302 O00255 26288158 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMK 5ddf A 1.66 BS01 5A1 A 1 S155 S178 E179 D180 H181 F238 C241 Y276 M278 N282 Y319 M322 Y323 S134 S157 E158 D159 H160 F217 C220 Y255 M257 N261 Y298 M301 Y302 O00255 26288158 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQ 5ddg A 3.06 BS01 NUC C 1 S163 K179 R180 R183 K184 S203 K204 R205 A207 A208 S164 K180 R181 R184 K185 S204 K205 R206 A208 A209 Q8AAV8 AMKNYYSSNPTFYLGIDCIIFGFNEGEISLLLLKRNFEPAMGEWSLMGGFVQKDESVDDAAKRVLAELTGLENVYMEQVGAFGAIDRDPGERVVSIAYYALININEYDRELVQKHNAYWVNINELPALIFDHPEMVDKAREMMKQKASVEPIGFNLLPKLFTLSQLQSLYEAIYGEPMDKRNFRKRVAEMDFIEKTDKIDKLGSKRGAALYKFNGKAYRKDPKFKL 5ddg A 3.06 BS02 NUC D 1 D178 R180 N181 K184 K204 R205 D179 R181 N182 K185 K205 R206 Q8AAV8 AMKNYYSSNPTFYLGIDCIIFGFNEGEISLLLLKRNFEPAMGEWSLMGGFVQKDESVDDAAKRVLAELTGLENVYMEQVGAFGAIDRDPGERVVSIAYYALININEYDRELVQKHNAYWVNINELPALIFDHPEMVDKAREMMKQKASVEPIGFNLLPKLFTLSQLQSLYEAIYGEPMDKRNFRKRVAEMDFIEKTDKIDKLGSKRGAALYKFNGKAYRKDPKFKL 5ddg B 3.06 BS02 NUC D 1 S163 K179 R180 R183 S203 K204 R205 A207 A208 S161 K177 R178 R181 S201 K202 R203 A205 A206 Q8AAV8 NYYSSNPTFYLGIDCIIFGFNEGEISLLLLKRNFEPAMGEWSLMGGFVQKDESVDDAAKRVLAELTGLENVYMEQVGAFGAIDRDPGERVVSIAYYALININEYDRELVQKHNAYWVNINELPALIFDHPEMVDKAREMMKQKASVEPIGFNLLPKLFTLSQLQSLYEAIYGEPMDKRNFRKRVAEMDFIEKTDKIDKLGSKRGAALYKFNGKAYRKDPKFKL