3jbq B 11.00 BS01 III D 1 N661 N662 S663 Q666 C677 H678 S679 L725 A726 L727 I729 K730 I802 P803 M804 L816 G819 F820 F823 V824 N130 N131 S132 Q135 C146 H147 S148 L194 A195 L196 I198 K199 I271 P272 M273 L285 G288 F289 F292 V293 25809480 SHMEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVCTQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQ 3jbq F 11.00 BS01 III X 1 N661 N662 S663 Q666 C677 H678 S679 L725 A726 L727 I729 K730 I802 P803 M804 L816 G819 F820 F823 V824 N130 N131 S132 Q135 C146 H147 S148 L194 A195 L196 I198 K199 I271 P272 M273 L285 G288 F289 F292 V293 25809480 SHMEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVCTQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQ 4pa5 A 1.86 BS01 DHL A 1 F69 E115 C116 Q183 G186 E187 F66 E112 C113 Q180 G183 E184 2.3.2.13 P40746 26322858 MIIVSGQLLRPQNWQIDQDLNPLLKEMIETPVQFDYHSIAELMFELKLRMNIVAAAKTLHKSGAKFATFLKTYGNTTYWRVSPEGALELKYRMPPSKAIRDIAENGPFYAFECATAIVIIYYLALIDTIGEDKFNASFDRIILYDWHYEKLPIYTETGHHFFLGDCLYFKNPEFDPQKAQWRGENVILLGEDKYFAHGLGILNGKQIIDKLNSFRKKGALQSAYLLSQATRLDVPSLFRIVR 4plu A 1.63 BS01 HBX A 1 P1 M2 H62 S63 I64 V106 P1 M2 H62 S63 I64 V106 5.3.2.1,5.3.3.12 P14174 26364929 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4plu A 1.63 BS02 HBX B 1 Y95 N97 Y95 N97 5.3.2.1,5.3.3.12 P14174 26364929 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4plu B 1.63 BS01 HBX B 1 P1 M2 S63 V106 P1 M2 S62 V105 5.3.2.1,5.3.3.12 P14174 26364929 PMFIVNTNVPRASVPDGFLELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4plu B 1.63 BS02 HBX C 1 Y95 N97 Y94 N96 5.3.2.1,5.3.3.12 P14174 26364929 PMFIVNTNVPRASVPDGFLELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4plu C 1.63 BS01 HBX A 1 Y95 N97 Y95 N97 5.3.2.1,5.3.3.12 P14174 26364929 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4plu C 1.63 BS02 HBX C 1 P1 M2 H62 S63 I64 V106 P1 M2 H62 S63 I64 V106 5.3.2.1,5.3.3.12 P14174 26364929 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4re9 A 2.91 BS01 ZN A 1 H108 H112 E189 H66 H70 E147 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 4re9 A 2.91 BS02 3M9 A 1 H108 E111 H112 F115 S128 N139 A140 E189 F820 R824 Y831 H66 E69 H70 F73 S86 N97 A98 E147 F778 R782 Y789 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 4re9 B 2.91 BS01 ZN B 1 H108 H112 E189 H66 H70 E147 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 4re9 B 2.91 BS02 3M9 B 1 H108 E111 H112 F115 S128 N139 A140 R824 Y831 H66 E69 H70 F73 S86 N97 A98 R782 Y789 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 4rf2 A 2.09 BS01 NAP A 1 G14 T16 L17 G18 I19 R39 H40 H62 D63 A64 N90 A91 G92 V113 M141 S142 S143 Y156 K160 P188 G189 Y190 I191 T193 P194 L195 V196 G12 T14 L15 G16 I17 R37 H38 H60 D61 A62 N88 A89 G90 V111 M139 S140 S141 Y154 K158 P186 G187 Y188 I189 T191 P192 L193 V194 Q6WVP7 DRLKGKVAIVTGGTLGIGLAIADKFVEEGAKVVITGRHADVGEKAAKSIGGTDVIRFVQHDASDEAGWTKLFDTTEEAFGPVTTVVNNAGIAVSKSVEDTTTEEWRKLLSVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGFVGDPTLGAYNASKGAVRIMSKSAALDCALKDYDVRVNTVHPGYIKTPLVDDLEGAEEMMSQRTKTPMGHIGEPNDIAWICVYLASDESKFATGAEFVVDGGYTAQ 4rf2 B 2.09 BS01 NAP B 1 G14 T16 L17 G18 I19 R39 H40 H62 D63 A64 N90 A91 G92 V113 M141 S142 S143 Y156 K160 P188 G189 Y190 I191 T193 P194 L195 V196 G12 T14 L15 G16 I17 R37 H38 H60 D61 A62 N88 A89 G90 V111 M139 S140 S141 Y154 K158 P186 G187 Y188 I189 T191 P192 L193 V194 Q6WVP7 DRLKGKVAIVTGGTLGIGLAIADKFVEEGAKVVITGRHADVGEKAAKSIGGTDVIRFVQHDASDEAGWTKLFDTTEEAFGPVTTVVNNAGIAVSKSVEDTTTEEWRKLLSVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGFVGDPTLGAYNASKGAVRIMSKSAALDCALKDYDVRVNTVHPGYIKTPLVDDLEGAEEMMSQRTKTPMGHIGEPNDIAWICVYLASDESKFATGAEFVVDGGYTAQ 4rlf A 1.73 BS01 3SK A 1 A227 Y228 A302 G303 I326 G327 S328 L332 H333 I334 A222 Y223 A297 G298 I321 G322 S323 L327 H328 I329 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREG 4rlf A 1.73 BS02 4MA A 1 A221 P251 T252 P253 G274 A275 G278 M282 A216 P246 T247 P248 G269 A270 G273 M277 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREG 4rlf B 1.73 BS01 3SK B 1 A227 Y228 A302 G303 I326 G327 S328 L332 H333 I334 K427 A222 Y223 A297 G298 I321 G322 S323 L327 H328 I329 K422 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVLG 4rlf B 1.73 BS02 4MA B 1 A221 P251 T252 P253 G274 A275 G278 M282 A216 P246 T247 P248 G269 A270 G273 M277 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVLG 4rlq A 1.63 BS01 3SK A 1 A227 Y228 G303 I326 G327 S328 L332 H333 I334 A222 Y223 G298 I321 G322 S323 L327 H328 I329 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVL 4rlq B 1.63 BS01 3SK B 1 A227 Y228 G303 I326 G327 S328 L332 H333 K427 Y432 A222 Y223 G298 I321 G322 S323 L327 H328 K422 Y427 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVLG 4rm2 A 1.77 BS01 3U4 A 1 A227 Y228 A302 G303 I326 G327 S328 L332 H333 I334 K427 A222 Y223 A297 G298 I321 G322 S323 L327 H328 I329 K422 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREG 4rm2 A 1.77 BS02 3U4 A 2 A221 P251 T252 V256 F272 G274 A275 G278 M282 A216 P246 T247 V251 F267 G269 A270 G273 M277 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREG 4rm2 B 1.77 BS01 3U4 B 1 A227 Y228 A302 G303 I326 G327 S328 L332 H333 I334 K427 A222 Y223 A297 G298 I321 G322 S323 L327 H328 I329 K422 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVLG 4rm3 A 1.76 BS01 FOA A 1 A227 Y228 A302 G303 G327 H333 I334 K427 A223 Y224 A298 G299 G323 H329 I330 K423 Q93TK0 AVTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGV 4rm3 B 1.76 BS01 FOA B 1 A227 Y228 A302 G303 I326 G327 S328 H333 I334 K427 A222 Y223 A297 G298 I321 G322 S323 H328 I329 K422 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVLG 4rmn A 1.72 BS01 C21 A 1 A227 Y228 A302 G303 G327 S328 L332 H333 I334 K427 A222 Y223 A297 G298 G322 S323 L327 H328 I329 K422 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVL 4rmn A 1.72 BS02 C21 A 2 A222 F226 Y228 G274 A275 A302 G430 A217 F221 Y223 G269 A270 A297 G425 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVL 4rmn B 1.72 BS01 C21 B 1 A227 Y228 A302 G303 I326 G327 S328 L332 H333 I334 K427 A222 Y223 A297 G298 I321 G322 S323 L327 H328 I329 K422 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVLG 4rmn B 1.72 BS02 C21 B 2 A222 F226 Y228 G274 A275 A302 G430 A217 F221 Y223 G269 A270 A297 G425 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVLG 4rmo A 2.20 BS01 NUC B 1 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 R69 C71 D72 I73 L88 Q90 D91 Q124 R127 K128 G131 M132 K134 R135 I137 K138 F139 T140 P141 T142 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 R69 C71 D72 I73 L88 Q90 D91 Q124 R127 K128 G131 M132 K134 R135 I137 K138 F139 T140 P141 T142 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo A 2.20 BS02 NUC F 1 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 H83 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 H83 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo C 2.20 BS01 NUC D 1 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 C71 D72 I73 L88 Q90 D91 K128 G131 M132 K134 R135 I137 K138 F139 T140 P141 T142 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 C71 D72 I73 L88 Q90 D91 K128 G131 M132 K134 R135 I137 K138 F139 T140 P141 T142 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo C 2.20 BS02 NUC H 1 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo E 2.20 BS01 NUC B 1 N29 R30 P31 L50 S51 S52 R53 K78 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 N29 R30 P31 L50 S51 S52 R53 K78 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo E 2.20 BS02 NUC F 1 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 C71 D72 I73 L88 Q90 D91 Q124 R127 K128 G131 M132 K134 R135 I137 K138 F139 T140 P141 T142 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 C71 D72 I73 L88 Q90 D91 Q124 R127 K128 G131 M132 K134 R135 I137 K138 F139 T140 P141 T142 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo G 2.20 BS01 NUC D 1 K26 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 K26 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo G 2.20 BS02 NUC H 1 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 C71 D72 I73 L88 Q90 D91 R127 K128 G131 M132 R135 I137 K138 F139 T140 P141 T142 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 C71 D72 I73 L88 Q90 D91 R127 K128 G131 M132 R135 I137 K138 F139 T140 P141 T142 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo I 2.20 BS01 NUC J 1 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 R64 R69 C71 D72 I73 L88 Q90 D91 Q124 R127 K128 G131 M132 K134 R135 K138 F139 T140 P141 T142 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 R64 R69 C71 D72 I73 L88 Q90 D91 Q124 R127 K128 G131 M132 K134 R135 K138 F139 T140 P141 T142 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo I 2.20 BS02 NUC L 1 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 T114 S115 E116 H117 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 T114 S115 E116 H117 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo K 2.20 BS01 NUC J 1 K26 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 K26 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo K 2.20 BS02 NUC L 1 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 R69 C71 D72 I73 L88 Q90 D91 Q124 K128 G131 M132 K134 R135 I137 K138 F139 T140 P141 T142 P20 Y21 L22 K23 G24 K26 R30 R53 K56 Y57 I60 K63 R64 R69 C71 D72 I73 L88 Q90 D91 Q124 K128 G131 M132 K134 R135 I137 K138 F139 T140 P141 T142 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo M 2.20 BS01 NUC N 1 P20 Y21 L22 K23 G24 K26 R30 S39 R53 K56 Y57 I60 K63 R64 C71 D72 I73 L88 Q90 D91 Q124 R127 K128 G131 M132 K134 R135 K138 F139 T140 P141 T142 P20 Y21 L22 K23 G24 K26 R30 S39 R53 K56 Y57 I60 K63 R64 C71 D72 I73 L88 Q90 D91 Q124 R127 K128 G131 M132 K134 R135 K138 F139 T140 P141 T142 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo M 2.20 BS02 NUC P 1 K26 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 H83 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 K26 N29 R30 P31 L50 S51 S52 R53 D80 D81 S82 H83 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo O 2.20 BS01 NUC N 1 N29 R30 P31 L50 S51 S52 R53 K78 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 N29 R30 P31 L50 S51 S52 R53 K78 D80 D81 S82 S85 R102 Y104 T105 I106 A107 N109 R112 T114 S115 E116 H117 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4rmo O 2.20 BS02 NUC P 1 P20 Y21 L22 K23 G24 K26 R30 K56 Y57 I60 K63 R64 R69 C71 D72 I73 L88 Q90 D91 R127 K128 G131 M132 K134 R135 K138 T140 P141 T142 P20 Y21 L22 K23 G24 K26 R30 K56 Y57 I60 K63 R64 R69 C71 D72 I73 L88 Q90 D91 R127 K128 G131 M132 K134 R135 K138 T140 P141 T142 D6E269 26350213 MIRNGFYIIKDRFFSDMSDPYLKGNKKQNRPHYYCFEDSNYNGIYWMIPLSSRIDKYKKIVSKRTGKGRNCDIIHIVKLDDSHESAFLIQDMFPISDKYIEREYTIAGNHLRLTSEHAAKEIEQKARKVLGMLKRGIKFTPTQPDIQKIYERLQQ 4trf A 1.63 BS01 35J A 1 P1 M2 F113 P1 M2 F113 5.3.2.1,5.3.3.12 P14174 26364929 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4trf B 1.63 BS01 35J B 1 P1 M2 Y36 F113 P1 M2 Y36 F113 5.3.2.1,5.3.3.12 P14174 26364929 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4trf C 1.63 BS01 35J C 1 P1 M2 K32 Y36 F113 P1 M2 K32 Y36 F113 5.3.2.1,5.3.3.12 P14174 26364929 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4ttv A 2.80 BS01 BC9 A 1 S386 G387 H388 M411 C413 R442 Y540 T560 D564 L567 H590 S66 G67 H68 M91 C93 R122 Y220 T240 D244 L247 H270 6.1.1.3 P26639 26271225 SDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 4ttv A 2.80 BS02 ZN A 1 C413 H464 H590 C93 H144 H270 6.1.1.3 P26639 26271225 SDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 4ttv B 2.80 BS01 BC9 B 1 G387 H388 M411 C413 R442 F539 Y540 T560 D564 L567 H590 G67 H68 M91 C93 R122 F219 Y220 T240 D244 L247 H270 6.1.1.3 P26639 26271225 SDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 4ttv B 2.80 BS02 ZN B 1 C413 H464 H590 C93 H144 H270 6.1.1.3 P26639 26271225 SDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 4ttv C 2.80 BS01 BC9 C 1 G387 H388 M411 C413 R442 F539 Y540 T560 D564 L567 H590 G67 H68 M91 C93 R122 F219 Y220 T240 D244 L247 H270 6.1.1.3 P26639 26271225 SDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 4ttv C 2.80 BS02 ZN C 1 C413 H464 H590 C93 H144 H270 6.1.1.3 P26639 26271225 SDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 4ttv D 2.80 BS01 BC9 D 1 G387 H388 M411 C413 R442 Y540 T560 D564 L567 H590 G67 H68 M91 C93 R122 Y220 T240 D244 L247 H270 6.1.1.3 P26639 26271225 SDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 4ttv D 2.80 BS02 ZN D 1 C413 H464 H590 C93 H144 H270 6.1.1.3 P26639 26271225 SDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 4uvd A 1.82 BS01 NAD A 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 G191 P192 I193 T195 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvd A 1.82 BS02 HRW A 1 G96 F97 M98 Q100 M199 A201 I202 A206 L207 G95 F96 M97 Q99 M198 A200 I201 A205 L206 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uve A 1.99 BS01 NAD A 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 G191 P192 I193 T195 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uve A 1.99 BS02 KI5 A 1 G96 F149 A198 M199 I202 G95 F148 A197 M198 I201 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvg A 1.92 BS01 NAD A 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 G191 P192 I193 T195 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvg A 1.92 BS02 A0C A 1 G96 F97 M98 F149 M161 M199 I202 G95 F96 M97 F148 M160 M198 I201 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvh A 1.89 BS01 NAD A 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 G191 P192 I193 T195 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvh A 1.89 BS02 UUD A 1 G96 F97 M98 G95 F96 M97 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvh B 1.89 BS01 NAD B 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I120 M145 D146 F147 K163 A189 G190 P191 I192 T194 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGNPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvh B 1.89 BS02 UUD B 1 G96 F97 M98 M161 G95 F96 M97 M159 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGNPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvh C 1.89 BS01 NAD C 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 G191 P192 I193 T195 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvh C 1.89 BS02 UUD C 1 G96 F97 M98 Q100 M103 G95 F96 M97 Q99 M102 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvh D 1.89 BS01 NAD D 1 G14 I15 I16 S20 I21 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 G13 I14 I15 S19 I20 L59 D60 V61 S90 I91 G92 I118 M143 D144 F145 K161 A187 G188 P189 I190 T192 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvh D 1.89 BS02 UUD D 1 G96 F97 M98 G92 F93 M94 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvi A 1.73 BS01 NAD A 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 G191 P192 I193 T195 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvi A 1.73 BS02 KXU A 1 G96 F97 M98 Q100 M103 F149 M161 G95 F96 M97 Q99 M102 F148 M160 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvi B 1.73 BS01 NAD B 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 P193 I194 T196 M199 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 P192 I193 T195 M198 1.3.1.9 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvi B 1.73 BS02 KXU B 1 G96 F97 M98 F149 Y158 M161 A198 M199 I202 G95 F96 M97 F148 Y157 M160 A197 M198 I201 1.3.1.9 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvi C 1.73 BS01 NAD C 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I121 M146 D147 F148 K164 A190 G191 P192 I193 T195 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvi C 1.73 BS02 KXU C 1 G96 F97 M98 Q100 M103 F149 M161 G95 F96 M97 Q99 M102 F148 M160 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvi D 1.73 BS01 NAD D 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 A191 G192 P193 I194 T196 M199 G13 I14 I15 S19 I20 F40 L58 D59 V60 S89 I90 G91 I117 M142 D143 F144 K160 A186 G187 P188 I189 T191 M194 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uvi D 1.73 BS02 KXU D 1 G96 F97 M98 Q100 M103 F149 M161 M199 G91 F92 M93 Q95 M98 F144 M156 M194 1.3.1.9 M9TGV3 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4uxx B 2.70 BS01 ACP C 1 R9 Y16 R4 Y11 2.7.1.107 GFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDACTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWCILLWSHFG 4uxx C 2.70 BS01 ZN C 1 E28 E76 E13 E61 2.7.1.107 P0ABN1 YSWKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDACTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWCILLWSHF 4uxx C 2.70 BS02 ACP C 1 E28 N72 E76 E85 Y86 H87 S90 G91 K94 D95 E13 N57 E61 E70 Y71 H72 S75 G76 K79 D80 2.7.1.107 P0ABN1 YSWKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDACTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWCILLWSHF 4uxz A 2.18 BS01 79N A 1 W18 R22 W25 M63 M66 W14 R18 W21 M59 M62 2.7.1.107 P0ABN1 TGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uxz A 2.18 BS02 79N A 2 V43 I44 W47 L48 F120 V39 I40 W43 L44 F116 2.7.1.107 P0ABN1 TGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uxz A 2.18 BS03 79N A 3 L40 W47 L36 W43 2.7.1.107 P0ABN1 TGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uxz A 2.18 BS04 79M A 1 A52 R55 A48 R51 2.7.1.107 P0ABN1 TGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uxz B 2.18 BS01 79M A 1 V109 A113 I114 W117 S118 V86 A90 I91 W94 S95 2.7.1.107 P0ABN1 AWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4uxz B 2.18 BS02 79M B 1 A46 V50 A52 R55 A23 V27 A29 R32 2.7.1.107 P0ABN1 AWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4uxz B 2.18 BS03 79M B 2 E34 A37 C41 V62 V65 E69 A108 W112 L116 F120 E11 A14 C18 V39 V42 E46 A85 W89 L93 F97 2.7.1.107 P0ABN1 AWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4uxz B 2.18 BS04 79M B 3 I44 D49 I21 D26 2.7.1.107 P0ABN1 AWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4uxz C 2.18 BS01 79M B 1 I110 A113 I114 W117 I79 A82 I83 W86 2.7.1.107 P0ABN1 RQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uxz D 2.18 BS01 ZN D 1 E28 E76 E15 E63 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uxz D 2.18 BS02 79N D 1 L40 W47 L48 F120 L27 W34 L35 F107 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uxz D 2.18 BS03 79M D 1 W25 I26 L39 W12 I13 L26 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uya A 2.80 BS01 AGS A 1 V138 A149 I184 L200 E201 F202 A203 D263 K265 N268 L270 D289 V21 A32 I57 L73 E74 F75 A76 D121 K123 N126 L128 D146 2.7.11.25 Q5TCX8 SPVHVAFERLELKELIGAGQVYRATWQGQEVAVKAAAAESVRREARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAGRRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDICNKTLKITDFGAYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAMTEMPQESFHSMQDDWKLEIQQMFDELRTKEK 4uya A 2.80 BS02 MG A 1 K265 N268 K123 N126 2.7.11.25 Q5TCX8 SPVHVAFERLELKELIGAGQVYRATWQGQEVAVKAAAAESVRREARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAGRRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDICNKTLKITDFGAYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAMTEMPQESFHSMQDDWKLEIQQMFDELRTKEK 4uyo A 2.18 BS01 79N A 1 W18 L21 R22 W25 W13 L16 R17 W20 2.7.1.107 P0ABN1 GFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo B 2.18 BS01 79M B 1 A46 V50 D51 A52 R55 A23 V27 D28 A29 R32 2.7.1.107 P0ABN1 AWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo B 2.18 BS02 79N B 1 E34 C41 V62 V65 E69 W112 E11 C18 V39 V42 E46 W89 2.7.1.107 P0ABN1 AWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo B 2.18 BS03 79M B 2 I44 W47 D49 I21 W24 D26 2.7.1.107 P0ABN1 AWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo C 2.18 BS01 79M B 1 I114 W117 I83 W86 2.7.1.107 P0ABN1 RQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo C 2.18 BS02 79N C 1 E34 C41 W112 L116 E3 C10 W81 L85 2.7.1.107 P0ABN1 RQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo D 2.18 BS01 ZN D 1 E28 E76 E15 E63 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo D 2.18 BS02 79N D 1 W25 A29 R32 V36 W12 A16 R19 V23 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo D 2.18 BS03 79N D 2 W47 L48 D49 F120 W34 L35 D36 F107 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo D 2.18 BS04 79M D 1 W25 G35 L39 W12 G22 L26 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4uyo F 2.18 BS01 79M F 1 E34 I44 V62 E69 I105 A108 V109 W112 L116 E9 I19 V37 E44 I80 A83 V84 W87 L91 2.7.1.107 P0ABN1 INEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4uzs A 1.74 BS01 POL A 1 D74 D78 N150 Y152 D72 D76 N148 Y150 3.2.1.23 E3EPA1 KRRKHSWPQPLKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDWLDRAIDKLGKAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEIIPPRYIGDGNFMNPGKLLDYKRFSSDALKELYIAERDVLESITPGLPLTTNFMVSAGGSMLDYDDWGAEVDFVSNDHYFTPGEAHFDEVAYAASLMDGISRKEPWFQMEHSTSAVNWRPINYRAEPGSVVRDSLAQVAMGADAICYFQWRQSKAGAEKWHSSMVPHAGEDSQIFRDVCELGADLGRLSDEGLMGTKTVKSKVAVVFDYESQWATEYTANPTQQVDHWTEPLDWFRALADNGITADVVPVRSDWDSYEIAVLPCVYLLSEETSRRVREFVANGGKLFVTYYTGLSDENDHIWLGGYPGSIRDVVGVRVEEFAPMGNDMPGALDHLDLDNGTVAHDFADVITSTADTSTVLASYKAERWTGMNEVPAIVANGYGDGRTVYVGCRLGRQGLAKSLPAMLGSMGLSDLAGDGRVLRVERADAAAASHFEFVFNRTHEPVTVDVEGEAIAASLAHVDDGRATIDPTGVVVLRR 4uzs A 1.74 BS02 POL A 2 R521 G525 V526 R527 S562 T563 A564 R519 G523 V524 R525 S560 T561 A562 3.2.1.23 E3EPA1 KRRKHSWPQPLKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDWLDRAIDKLGKAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEIIPPRYIGDGNFMNPGKLLDYKRFSSDALKELYIAERDVLESITPGLPLTTNFMVSAGGSMLDYDDWGAEVDFVSNDHYFTPGEAHFDEVAYAASLMDGISRKEPWFQMEHSTSAVNWRPINYRAEPGSVVRDSLAQVAMGADAICYFQWRQSKAGAEKWHSSMVPHAGEDSQIFRDVCELGADLGRLSDEGLMGTKTVKSKVAVVFDYESQWATEYTANPTQQVDHWTEPLDWFRALADNGITADVVPVRSDWDSYEIAVLPCVYLLSEETSRRVREFVANGGKLFVTYYTGLSDENDHIWLGGYPGSIRDVVGVRVEEFAPMGNDMPGALDHLDLDNGTVAHDFADVITSTADTSTVLASYKAERWTGMNEVPAIVANGYGDGRTVYVGCRLGRQGLAKSLPAMLGSMGLSDLAGDGRVLRVERADAAAASHFEFVFNRTHEPVTVDVEGEAIAASLAHVDDGRATIDPTGVVVLRR 4uzs A 1.74 BS03 POL A 3 A670 H671 T678 D680 A668 H669 T676 D678 3.2.1.23 E3EPA1 KRRKHSWPQPLKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDWLDRAIDKLGKAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEIIPPRYIGDGNFMNPGKLLDYKRFSSDALKELYIAERDVLESITPGLPLTTNFMVSAGGSMLDYDDWGAEVDFVSNDHYFTPGEAHFDEVAYAASLMDGISRKEPWFQMEHSTSAVNWRPINYRAEPGSVVRDSLAQVAMGADAICYFQWRQSKAGAEKWHSSMVPHAGEDSQIFRDVCELGADLGRLSDEGLMGTKTVKSKVAVVFDYESQWATEYTANPTQQVDHWTEPLDWFRALADNGITADVVPVRSDWDSYEIAVLPCVYLLSEETSRRVREFVANGGKLFVTYYTGLSDENDHIWLGGYPGSIRDVVGVRVEEFAPMGNDMPGALDHLDLDNGTVAHDFADVITSTADTSTVLASYKAERWTGMNEVPAIVANGYGDGRTVYVGCRLGRQGLAKSLPAMLGSMGLSDLAGDGRVLRVERADAAAASHFEFVFNRTHEPVTVDVEGEAIAASLAHVDDGRATIDPTGVVVLRR 4uzs B 1.74 BS01 POL B 1 D74 H146 Y147 N150 D71 H143 Y144 N147 3.2.1.23 E3EPA1 RRKHSWPQPLKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDWLDRAIDKLGKAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEIIPPRYIGDGNFMNPGKLLDYKRFSSDALKELYIAERDVLESITPGLPLTTNFMVSAGGSMLDYDDWGAEVDFVSNDHYFTPGEAHFDEVAYAASLMDGISRKEPWFQMEHSTSAVNWRPINYRAEPGSVVRDSLAQVAMGADAICYFQWRQSKAGAEKWHSSMVPHAGEDSQIFRDVCELGADLGRLSDEGLMGTKTVKSKVAVVFDYESQWATEYTANPTQQVDHWTEPLDWFRALADNGITADVVPVRSDWDSYEIAVLPCVYLLSEETSRRVREFVANGGKLFVTYYTGLSDENDHIWLGGYPGSIRDVVGVRVEEFAPMGNDMPGALDHLDLDNGTVAHDFADVITSTADTSTVLASYKAERWTGMNEVPAIVANGYGDGRTVYVGCRLGRQGLAKSLPAMLGSMGLSGDGRVLRVERADSHFEFVFNRTHEPVTVDVEGEAIAASLAHVDDGRATIDPTGVVVLRR 4uzs C 1.74 BS01 POL C 1 D506 I511 D504 I509 3.2.1.23 E3EPA1 KRRKHSWPQPLKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDWLDRAIDKLGKAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEIIPPRYIGDGNFMNPGKLLDYKRFSSDALKELYIAERDVLESITPGLPLTTNFMVSAGGSMLDYDDWGAEVDFVSNDHYFTPGEAHFDEVAYAASLMDGISRKEPWFQMEHSTSAVNWRPINYRAEPGSVVRDSLAQVAMGADAICYFQWRQSKAGAEKWHSSMVPHAGEDSQIFRDVCELGADLGRLSDEGLMGTKTVKSKVAVVFDYESQWATEYTANPTQQVDHWTEPLDWFRALADNGITADVVPVRSDWDSYEIAVLPCVYLLSEETSRRVREFVANGGKLFVTYYTGLSDENDHIWLGGYPGSIRDVVGVRVEEFAPMGNDMPGALDHLDLDNGTVAHDFADVITSTADTSTVLASYKAERWTGMNEVPAIVANGYGDGRTVYVGCRLGRQGLAKSLPAMLGSMGLSDLAGDGRVLRVERADSHFEFVFNRTHEPVTVDVEGEAIAASLAHVDDGRATIDPTGVVVLRR 4v0i A 2.54 BS01 J82 A 1 F751 M752 P758 L759 W760 I777 K779 Y813 I825 E826 V827 V828 M900 F908 I910 D911 F504 M505 P511 L512 W513 I530 K532 Y566 I578 E579 V580 V581 M646 F654 I656 D657 2.7.1.153 KKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNQPFSIELIVQAGLFHGNEMLCKTDISVCDLPRMARLCFALYADCPIAWANLMLFDYKDQLKTGERCLYMWPSLLNPAGTVRGNPNTESAAALVIYLPEVAPVYFPALEKILELEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLTAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRES 4v0i B 2.54 BS01 J82 B 1 F751 M752 P758 W760 I777 K779 Y813 I825 E826 V827 V828 M900 I910 D911 F537 M538 P544 W546 I563 K565 Y599 I611 E612 V613 V614 M679 I689 D690 2.7.1.153 O35904 KLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSAVSNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNEQPFSIELIEGRKVNAMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYADCPIAWANLMLFDYKDQLKTGERCLYMWPSLLNPAGTVRGNPNTESAAALVIYLPEVAPVYFPALEKILELEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLTAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRES 4v0z A 1.70 BS01 CO A 1 E295 N301 E325 E295 N301 E325 3.2.1.176 P62694 QSACTLQSETHPPLTWQKCSSGGTCTQQTGSVVIDANWRWTHATNSSTNCYDGNTWSSTLCPDNETCAKNCCLDGAAYASTYGVTTSGNSLSIGFVTQSAQKNVGARLYLMASDTTYQEFTLLGNEFSFDVDVSQLPCGLNGALYFVSMDADGGVSKYPTNTAGAKYGTGYCDSQCPRDLKFINGQANVEGWEPSSNNANTGIGGHGSCCSEMDIWEANSISEALTPHPCTTVGQEICEGDGCGGTYSDNRYGGTCDPDGCDWNPYRLGNTSFYGPGSSFTLDTTKKLTVVTQFETSGAINRYYVQDGVTFQQPNAELGSYSGNELNDDYCTAEEAEFGGSSFSDKGGLTQFKKATSGGMVLVMSLWDDYYANMLWLDSTYPTNETSSTPGAVRGSCSTSSGVPAQVESQSPNAKVTFSNIKFGPIGSTGNPSG 4v0z A 1.70 BS02 CO A 2 H206 E239 H206 E239 3.2.1.176 P62694 QSACTLQSETHPPLTWQKCSSGGTCTQQTGSVVIDANWRWTHATNSSTNCYDGNTWSSTLCPDNETCAKNCCLDGAAYASTYGVTTSGNSLSIGFVTQSAQKNVGARLYLMASDTTYQEFTLLGNEFSFDVDVSQLPCGLNGALYFVSMDADGGVSKYPTNTAGAKYGTGYCDSQCPRDLKFINGQANVEGWEPSSNNANTGIGGHGSCCSEMDIWEANSISEALTPHPCTTVGQEICEGDGCGGTYSDNRYGGTCDPDGCDWNPYRLGNTSFYGPGSSFTLDTTKKLTVVTQFETSGAINRYYVQDGVTFQQPNAELGSYSGNELNDDYCTAEEAEFGGSSFSDKGGLTQFKKATSGGMVLVMSLWDDYYANMLWLDSTYPTNETSSTPGAVRGSCSTSSGVPAQVESQSPNAKVTFSNIKFGPIGSTGNPSG 4v0z A 1.70 BS03 OPO A 1 F338 Y381 P382 R394 F338 Y381 P382 R394 3.2.1.176 P62694 QSACTLQSETHPPLTWQKCSSGGTCTQQTGSVVIDANWRWTHATNSSTNCYDGNTWSSTLCPDNETCAKNCCLDGAAYASTYGVTTSGNSLSIGFVTQSAQKNVGARLYLMASDTTYQEFTLLGNEFSFDVDVSQLPCGLNGALYFVSMDADGGVSKYPTNTAGAKYGTGYCDSQCPRDLKFINGQANVEGWEPSSNNANTGIGGHGSCCSEMDIWEANSISEALTPHPCTTVGQEICEGDGCGGTYSDNRYGGTCDPDGCDWNPYRLGNTSFYGPGSSFTLDTTKKLTVVTQFETSGAINRYYVQDGVTFQQPNAELGSYSGNELNDDYCTAEEAEFGGSSFSDKGGLTQFKKATSGGMVLVMSLWDDYYANMLWLDSTYPTNETSSTPGAVRGSCSTSSGVPAQVESQSPNAKVTFSNIKFGPIGSTGNPSG 4v0z A 1.70 BS04 BGC A 1 R251 D259 Y381 R394 R251 D259 Y381 R394 3.2.1.176 P62694 QSACTLQSETHPPLTWQKCSSGGTCTQQTGSVVIDANWRWTHATNSSTNCYDGNTWSSTLCPDNETCAKNCCLDGAAYASTYGVTTSGNSLSIGFVTQSAQKNVGARLYLMASDTTYQEFTLLGNEFSFDVDVSQLPCGLNGALYFVSMDADGGVSKYPTNTAGAKYGTGYCDSQCPRDLKFINGQANVEGWEPSSNNANTGIGGHGSCCSEMDIWEANSISEALTPHPCTTVGQEICEGDGCGGTYSDNRYGGTCDPDGCDWNPYRLGNTSFYGPGSSFTLDTTKKLTVVTQFETSGAINRYYVQDGVTFQQPNAELGSYSGNELNDDYCTAEEAEFGGSSFSDKGGLTQFKKATSGGMVLVMSLWDDYYANMLWLDSTYPTNETSSTPGAVRGSCSTSSGVPAQVESQSPNAKVTFSNIKFGPIGSTGNPSG 4v0z A 1.70 BS05 BGC A 2 Q175 D214 E217 H228 T246 R251 P258 D259 W376 Q175 D214 E217 H228 T246 R251 P258 D259 W376 3.2.1.176 P62694 QSACTLQSETHPPLTWQKCSSGGTCTQQTGSVVIDANWRWTHATNSSTNCYDGNTWSSTLCPDNETCAKNCCLDGAAYASTYGVTTSGNSLSIGFVTQSAQKNVGARLYLMASDTTYQEFTLLGNEFSFDVDVSQLPCGLNGALYFVSMDADGGVSKYPTNTAGAKYGTGYCDSQCPRDLKFINGQANVEGWEPSSNNANTGIGGHGSCCSEMDIWEANSISEALTPHPCTTVGQEICEGDGCGGTYSDNRYGGTCDPDGCDWNPYRLGNTSFYGPGSSFTLDTTKKLTVVTQFETSGAINRYYVQDGVTFQQPNAELGSYSGNELNDDYCTAEEAEFGGSSFSDKGGLTQFKKATSGGMVLVMSLWDDYYANMLWLDSTYPTNETSSTPGAVRGSCSTSSGVPAQVESQSPNAKVTFSNIKFGPIGSTGNPSG 4wcd A 1.68 BS01 NAP A 1 R14 I15 H33 Y34 H35 N36 S37 A61 D62 L63 T64 N93 A94 S95 T126 L159 C160 Y174 K178 P204 G205 S207 L208 R13 I14 H32 Y33 H34 N35 S36 A60 D61 L62 T63 N92 A93 S94 T117 L141 C142 Y156 K160 P186 G187 S189 L190 O76290 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4wcd A 1.68 BS02 3KH A 1 R14 F97 Y174 V206 P210 W221 R13 F96 Y156 V188 P192 W203 O76290 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4wcd B 1.68 BS01 NAP B 1 G10 R14 I15 H33 Y34 H35 N36 S37 A61 D62 L63 T64 N93 A94 S95 T126 L159 C160 D161 Y174 K178 P204 G205 S207 L208 G9 R13 I14 H32 Y33 H34 N35 S36 A60 D61 L62 T63 N92 A93 S94 T117 L141 C142 D143 Y156 K160 P186 G187 S189 L190 O76290 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4wcd B 1.68 BS02 3KH B 1 R14 F97 V206 L209 W221 R13 F96 V188 L191 W203 O76290 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4wcd D 1.68 BS01 NAP D 1 G10 R14 I15 H33 Y34 H35 N36 S37 A61 D62 L63 T64 N93 A94 S95 T126 L159 C160 D161 Y174 K178 P204 G205 V206 S207 L208 G9 R13 I14 H32 Y33 H34 N35 S36 A60 D61 L62 T63 N92 A93 S94 T116 L140 C141 D142 Y155 K159 P185 G186 V187 S188 L189 O76290 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4wcd D 1.68 BS02 3KH D 1 R14 F97 Y174 V206 P210 W221 R13 F96 Y155 V187 P191 W202 O76290 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4wdd A 2.10 BS01 CIT A 1 Y168 H230 A232 H309 P320 V321 Y8 H66 A68 H138 P149 V150 3.1.4.37 P16330 EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGEKLELVSYFGKRPPGVLHCATKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 4we3 A 2.60 BS01 NAP A 1 P60 M143 T147 A168 G171 A172 V173 A192 G193 K197 Y213 N237 V238 C259 G260 F289 L290 V291 P53 M136 T140 A161 G164 A165 V166 A185 G186 K190 Y206 N230 V231 C252 G253 F273 L274 V275 DVVVVNKQVLLKHFIPAPKETDMELVTTGTIRLRVPEGSNAVLLKNLYLSCDPYMRMRMTKHEEASYVDDFVPGAPITGFGVGKVVDSSHPDFKTGDYVWGLIGWEEYSLITKPQGLFKIHHTEIPLSYYTGILGMVGLTAYVGFYDICSPKKGERVFVSAAAGAVGQIVGQFAKQFGCYVVGSAGSDEKVNLLKTKFGFDEAFNYKKEPDLTKALKRYFPEGIDIYFENVGGPMLEAVLHNMRIKGRIAACGMIGVHNLFLIVGKRIRLEGFLVFDHYGSYPEFEEKVVQLIKEEKIKYLEDIVEGLENAPAALIGLFEGRNVGKQVVVVSREKGHHHHHH 4we3 B 2.60 BS01 NAP B 1 P60 M143 T147 G171 A172 V173 A192 G193 K197 Y213 N237 C259 G260 I262 S263 Y265 F289 L290 V291 L334 F335 G337 N339 P52 M135 T139 G163 A164 V165 A184 G185 K189 Y205 N229 C251 G252 I254 S255 Y257 F280 L281 V282 L325 F326 G328 N330 VVVVNKQVLLKHFIPAPKETDMELVTTGTIRLRVPEGSNAVLLKNLYLSCDPYMRMRMTKHEEASYVDDFVPGAPITGFGVGKVVDSSHPDFKTGDYVWGLIGWEEYSLITKPQGLFKIHHTEIPLSYYTGILGMVGLTAYVGFYDICSPKKGERVFVSAAAGAVGQIVGQFAKQFGCYVVGSAGSDEKVNLLKTKFGFDEAFNYKKEPDLTKALKRYFPEGIDIYFENVGGPMLEAVLHNMRIKGRIAACGMISQYNLKPEGVHNLFLIVGKRIRLEGFLVFDHYGSYPEFEEKVVQLIKEEKIKYLEDIVEGLENAPAALIGLFEGRNVGKQVVVVSR 4we3 C 2.60 BS01 NAP C 1 P60 M143 T147 G171 A172 V173 A192 G193 K197 Y213 N237 V238 C259 G260 I262 S263 Y265 F289 L290 V291 L334 F335 G337 N339 P54 M137 T141 G165 A166 V167 A186 G187 K191 Y207 N231 V232 C253 G254 I256 S257 Y259 F283 L284 V285 L328 F329 G331 N333 VVVVNKQVLLKHFIPEGAPKETDMELVTTGTIRLRVPEGSNAVLLKNLYLSCDPYMRMRMTKHEEASYVDDFVPGAPITGFGVGKVVDSSHPDFKTGDYVWGLIGWEEYSLITKPQGLFKIHHTEIPLSYYTGILGMVGLTAYVGFYDICSPKKGERVFVSAAAGAVGQIVGQFAKQFGCYVVGSAGSDEKVNLLKTKFGFDEAFNYKKEPDLTKALKRYFPEGIDIYFENVGGPMLEAVLHNMRIKGRIAACGMISQYNLEKPEGVHNLFLIVGKRIRLEGFLVFDHYGSYPEFEEKVVQLIKEEKIKYLEDIVEGLENAPAALIGLFEGRNVGKQVVVVSR 4we3 D 2.60 BS01 NAP D 1 P60 M143 T147 G171 A172 V173 A192 G193 K197 Y213 N237 V238 C259 G260 I262 Y265 F289 L290 V291 L334 F335 G337 N339 P50 M133 T137 G161 A162 V163 A182 G183 K187 Y203 N227 V228 C249 G250 I252 Y255 F277 L278 V279 L322 F323 G325 N327 VVVNKQVLLKHFIAPKETDMELVTTGTIRLRVPEGSNAVLLKNLYLSCDPYMRMRMTKHEEASYVDDFVPGAPITGFGVGKVVDSSHPDFKTGDYVWGLIGWEEYSLITKPQGLFKIHHTEIPLSYYTGILGMVGLTAYVGFYDICSPKKGERVFVSAAAGAVGQIVGQFAKQFGCYVVGSAGSDEKVNLLKTKFGFDEAFNYKKEPDLTKALKRYFPEGIDIYFENVGGPMLEAVLHNMRIKGRIAACGMISQYNLPEGVHNLFLIVGKRIRLEGFLVFDHYGSYPEFEEKVVQLIKEEKIKYLEDIVEGLENAPAALIGLFEGRNVGKQVVVVSRHHHHH 4wfo A 1.14 BS01 MN A 1 H499 H504 H690 N694 I839 H486 H491 H677 N681 I826 1.13.11.12 P08170 GHKIKGTVVLMPKNELENLNAFLGRSVSLQLISATKADAHGKGKVGKDTFLEGINTSLPTLGAGESAFNIHFEWDGSMGIPGAFYIKNYMQVEFFLKSLTLEAISNQGTIRFVCNSWVYNTKLYKSVRIFFANHTYVPSETPAPLVEYREEELKSLRGNGTGERKEYDRIYDYDVYNDLGNPDKSEKLARPVLGGSSTFPYPRRGRTGRGPTVTDPNTEKQGEVFYVPRDENLGHLKSKDALEIGTKSLSQIVQPAFESAFDLKSTPIEFHSFQDVHDLYEGGIKLPRDVISTIIPLPVIKELYRTDGQHILKFPQPHVVQVSQSAWMTDEEFAREMIAGVNPCVIRGLEEFPPKSNLDPAIYGDQSSKITADSLDLDGYTMDEALGSRRLFMLDYHDIFMPYVRQINQLNSAKTYATRTILFLREDGTLKPVAIELSLPHSAGDLSAAVSQVVLPAKEGVESTIWLLAKAYVIVNDSCYHQLMSHWLNTHAAMEPFVIATHRHLSVLHPIYKLLTPHYRNNMNINALARQSLINANGIIETTFLPSKYSVEMSSAVYKNWVFTDQALPADLIKRGVAIKDPSTPHGVRLLIEDYPYAADGLEIWAAIKTWVQEYVPLYYARDDDVKNDSELQHWWKEAVEKGHGDLKDKPWWPKLQTLEDLVEVCLIIIWIASALHAAVNFGQYPYGGLIMNRPTASRRLLPEKGTPEYEEMINNHEKAYLRTITSKLPTLISLSVIEILSTHASDEVYLGQRDNPHWTSDSKALQAFQKFGNKLKEIEEKLVRRNNDPSLQGNRLGPVQLPYTLLYPSSEEGLTFRGIPNSISI 4wfr A 2.00 BS01 2AM A 1 Y168 H230 F235 H309 T311 P320 V321 Y7 H64 F69 H139 T141 P150 V151 3.1.4.37 P16330 KDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISEKLELVSYFGKRPPGVLHCATKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 4wgg A 2.40 BS01 NAP A 1 P60 M143 T147 G171 A172 V173 A192 G193 K197 Y213 N237 V238 C259 G260 I262 S263 Y265 F289 L290 V291 L334 F335 G337 N339 P54 M137 T141 G165 A166 V167 A186 G187 K191 Y207 N231 V232 C253 G254 I256 S257 Y259 F283 L284 V285 L328 F329 G331 N333 VVVVNKQVLLKHFIPEGAPKETDMELVTTGTIRLRVPEGSNAVLLKNLYLSCDPYMRMRMTKHEEASYVDDFVPGAPITGFGVGKVVDSSHPDFKTGDYVWGLIGWEEYSLITKPQGLFKIHHTEIPLSYYTGILGMVGLTAYVGFYDICSPKKGERVFVSAAAGAVGQIVGQFAKQFGCYVVGSAGSDEKVNLLKTKFGFDEAFNYKKEPDLTKALKRYFPEGIDIYFENVGGPMLEAVLHNMRIKGRIAACGMISQYNLEKPEGVHNLFLIVGKRIRLEGFLVFDHYGSYPEFEEKVVQLIKEEKIKYLEDIVEGLENAPAALIGLFEGRNVGKQVVVVSREKGHHHHHH 4wgg A 2.40 BS02 CIY A 1 Y61 M64 Y74 Y265 L290 V291 F292 Y55 M58 Y68 Y259 L284 V285 F286 VVVVNKQVLLKHFIPEGAPKETDMELVTTGTIRLRVPEGSNAVLLKNLYLSCDPYMRMRMTKHEEASYVDDFVPGAPITGFGVGKVVDSSHPDFKTGDYVWGLIGWEEYSLITKPQGLFKIHHTEIPLSYYTGILGMVGLTAYVGFYDICSPKKGERVFVSAAAGAVGQIVGQFAKQFGCYVVGSAGSDEKVNLLKTKFGFDEAFNYKKEPDLTKALKRYFPEGIDIYFENVGGPMLEAVLHNMRIKGRIAACGMISQYNLEKPEGVHNLFLIVGKRIRLEGFLVFDHYGSYPEFEEKVVQLIKEEKIKYLEDIVEGLENAPAALIGLFEGRNVGKQVVVVSREKGHHHHHH 4wgg B 2.40 BS01 NAP B 1 P60 M143 T147 A168 G171 A172 V173 A192 G193 K197 Y213 N237 C259 G260 I262 Y265 F289 L290 V291 G337 N339 P54 M137 T141 A162 G165 A166 V167 A186 G187 K191 Y207 N231 C253 G254 I256 Y259 F278 L279 V280 G326 N328 VVVVNKQVLLKHFIPEGAPKETDMELVTTGTIRLRVPEGSNAVLLKNLYLSCDPYMRMRMTKHEEASYVDDFVPGAPITGFGVGKVVDSSHPDFKTGDYVWGLIGWEEYSLITKPQGLFKIHHTEIPLSYYTGILGMVGLTAYVGFYDICSPKKGERVFVSAAAGAVGQIVGQFAKQFGCYVVGSAGSDEKVNLLKTKFGFDEAFNYKKEPDLTKALKRYFPEGIDIYFENVGGPMLEAVLHNMRIKGRIAACGMISQYNGVHNLFLIVGKRIRLEGFLVFDHYGSYPEFEEKVVQLIKEEKIKYLEDIVEGLENAPAALIGLFEGRNVGKQVVVVSREKGHHHHH 4whv C 8.30 BS01 ZN C 1 C418 H420 C437 C440 C74 H76 C93 C96 6.3.2.- O76064 QEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERK 4whv C 8.30 BS02 ZN C 2 C403 C406 C423 C426 C59 C62 C79 C82 6.3.2.- O76064 QEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERK 4whv D 8.30 BS01 ZN D 1 C418 H420 C437 C440 C77 H79 C96 C99 6.3.2.- O76064 PEFQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERK 4whv D 8.30 BS02 ZN D 2 C403 C406 C423 C426 C62 C65 C82 C85 6.3.2.- O76064 PEFQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERK 4whv I 8.30 BS01 ZN I 1 C418 H420 C437 C440 C39 H41 C58 C61 6.3.2.- O76064 EKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERK 4whv I 8.30 BS02 ZN I 2 C403 C406 C423 C426 C24 C27 C44 C47 6.3.2.- O76064 EKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERK 4whv J 8.30 BS01 ZN J 1 C418 H420 C437 C440 C39 H41 C58 C61 6.3.2.- O76064 EKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERK 4whv J 8.30 BS02 ZN J 2 C403 C406 C423 C426 C24 C27 C44 C47 6.3.2.- O76064 EKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERK 4wi2 A 1.90 BS01 FUC A 1 Q295 Y296 N297 Q59 Y60 N61 P01857 GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLS 4wi5 A 2.80 BS01 FUC A 1 Q295 N297 Q59 N61 P01857 GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLAQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLS 4wi8 A 2.80 BS01 FUC A 1 Q295 Y296 Q59 Y60 P01857 GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHATQKSLSLS 4wi8 B 2.80 BS01 FUC B 1 Q295 N297 Q59 N61 P01857 GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHATQKSLSLS 4wi9 A 2.65 BS01 FUC A 1 Q295 Y296 Q59 Y60 P01857 GPSVFLFPPKPKDTLMASRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLAQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLS 4wj8 A 2.87 BS01 OXD A 1 K270 E272 M291 A293 G295 D296 T328 K257 E259 M278 A280 G282 D283 T315 2.7.1.40 P14618 QTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wj8 A 2.87 BS02 FBP A 1 L431 T432 K433 S434 R436 S437 R489 G514 R516 P517 G518 S519 G520 F521 T522 L418 T419 K420 S421 R423 S424 R476 G501 R503 P504 G505 S506 G507 F508 T509 2.7.1.40 P14618 QTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wj8 A 2.87 BS03 MG A 1 K270 E272 D296 K257 E259 D283 2.7.1.40 P14618 QTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wj8 B 2.87 BS01 OXD B 1 K270 E272 A293 R294 G295 D296 T328 K256 E258 A279 R280 G281 D282 T314 2.7.1.40 P14618 TQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wj8 B 2.87 BS02 MG B 1 E272 D296 E258 D282 2.7.1.40 P14618 TQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wj8 C 2.87 BS01 FBP C 1 L431 T432 K433 S434 S437 R489 T513 G514 R516 P517 G518 S519 G520 F521 T522 L416 T417 K418 S419 S422 R474 T498 G499 R501 P502 G503 S504 G505 F506 T507 2.7.1.40 P14618 QQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wj8 C 2.87 BS02 OXD C 1 K270 E272 A293 R294 G295 D296 T328 K255 E257 A278 R279 G280 D281 T313 2.7.1.40 P14618 QQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wj8 C 2.87 BS03 MG C 1 E272 D296 E257 D281 2.7.1.40 P14618 QQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wj8 D 2.87 BS01 OXD D 1 K270 E272 A293 R294 G295 D296 T328 K256 E258 A279 R280 G281 D282 T314 2.7.1.40 P14618 TQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wj8 D 2.87 BS02 MG D 1 E272 D296 E258 D282 2.7.1.40 P14618 TQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCASGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4wlm A 3.00 BS01 MN A 1 D225 D227 H382 D122 D124 H279 2.4.2.- Q3U4G3 PVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPI 4wlm B 3.00 BS01 MN B 1 D225 D227 H382 D125 D127 H282 2.4.2.- Q3U4G3 VDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIP 4wm0 A 2.37 BS01 GCX D 1 E255 Q257 Q330 C356 W358 W359 N384 C385 E163 Q165 Q238 C264 W266 W267 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wma A 1.62 BS01 MN A 1 D225 D227 H382 N384 D133 D135 H290 N292 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wma A 1.62 BS02 UPG A 1 M103 F104 T105 L113 D225 L226 D227 S289 L327 Q330 H382 N384 C385 M11 F12 T13 L21 D133 L134 D135 S197 L235 Q238 H290 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wma A 1.62 BS03 GCX D 1 E255 Q257 V259 Q330 C356 W358 W359 N384 C385 E163 Q165 V167 Q238 C264 W266 W267 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wmb A 2.05 BS01 MN A 1 D225 D227 H382 N384 D133 D135 H290 N292 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wmb A 2.05 BS02 UDP A 1 M103 F104 T105 L113 D225 L226 D227 H382 N384 C385 M11 F12 T13 L21 D133 L134 D135 H290 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wmb A 2.05 BS03 GCX D 1 E255 Q257 Q330 C356 W358 W359 N384 C385 E163 Q165 Q238 C264 W266 W267 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wmb D 2.05 BS01 GCX D 1 E52 S53 E3 S4 3.4.21.22 P00740 QCESNPCLNGGSCKDDINSYECWCPFGFEGKNCEL 4wmi A 1.87 BS01 MN A 1 D225 D227 H382 N384 D133 D135 H290 N292 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wmi A 1.87 BS02 UDP A 1 M103 F104 T105 L113 D225 L226 D227 H382 N384 C385 M11 F12 T13 L21 D133 L134 D135 H290 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wmi A 1.87 BS03 GXX D 1 D225 E255 Q257 V259 N288 S289 G290 L327 Q330 C356 W358 W359 H382 N384 C385 D133 E163 Q165 V167 N196 S197 G198 L235 Q238 C264 W266 W267 H290 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wmi D 1.87 BS01 GXX D 1 E52 S53 E3 S4 3.4.21.22 P00740 QCESNPCLNGGSCKDDINSYECWCPFGFEGKNCEL 4wmk A 2.08 BS01 MN A 1 D225 D227 H382 N384 D133 D135 H290 N292 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wmk A 2.08 BS02 UDP A 1 M103 F104 T105 L113 K116 D225 L226 D227 H382 N384 C385 M11 F12 T13 L21 K24 D133 L134 D135 H290 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wmk A 2.08 BS03 GXX D 1 D225 E255 Q257 V259 N288 S289 G290 Q330 C356 W358 W359 H382 N384 C385 D133 E163 Q165 V167 N196 S197 G198 Q238 C264 W266 W267 H290 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wn2 A 1.95 BS01 MN A 1 D225 D227 H382 N384 D133 D135 H290 N292 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wn2 A 1.95 BS02 UDP A 1 M103 F104 T105 L113 D225 L226 D227 H382 N384 C385 M11 F12 T13 L21 D133 L134 D135 H290 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wn2 A 1.95 BS03 GXX D 1 D225 E255 Q257 V259 N288 S289 G290 L327 Q330 C356 W358 W359 H382 N384 C385 D133 E163 Q165 V167 N196 S197 G198 L235 Q238 C264 W266 W267 H290 N292 C293 2.4.2.- Q3U4G3 VVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wnh A 1.95 BS01 MN A 1 D225 D227 H382 N384 D132 D134 H289 N291 2.4.2.- Q3U4G3 VPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wnh A 1.95 BS02 UDX A 1 M103 F104 T105 L113 D225 L226 D227 S289 L327 Q330 H382 N384 C385 M10 F11 T12 L20 D132 L133 D134 S196 L234 Q237 H289 N291 C292 2.4.2.- Q3U4G3 VPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4wnh A 1.95 BS03 GCX D 1 E255 Q257 V259 Q330 C356 W358 W359 N384 C385 E162 Q164 V166 Q237 C263 W265 W266 N291 C292 2.4.2.- Q3U4G3 VPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPE 4x6i A 1.87 BS01 3Y1 A 1 C25 W26 E59 N60 D61 G64 G65 G66 Y67 A134 L160 N161 L209 C25 W26 E59 N60 D61 G64 G65 G66 Y67 A134 L160 N161 L209 3.4.22.38 P43235 26280490 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 4xhu A 2.09 BS01 CA A 1 D766 Y889 D100 Y218 2.4.2.30 P09874 26344098 TKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTS 4xmb A 2.43 BS01 41P A 1 Y334 S363 G364 R380 N414 R415 I461 G462 F478 S508 G509 Y525 Q530 S555 A556 Y572 F577 S602 G603 Y11 S40 G41 R57 N91 R92 I138 G139 F155 S185 G186 Y202 Q207 S232 A233 Y249 F254 S279 G280 Q14145 26363505 VGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 4xz9 B 1.80 BS01 PDO B 1 D6 T26 N28 K86 N108 S130 Y132 D6 T26 N28 K86 N108 S130 Y132 2.2.1.2 Q9HKI3 26131847 MKIFLDTANIDEIRTGVNWGIVDGVTTNPTLISKEAVNGKKYGDIIREILKIVDGPVSVQVVSTKYEGMVEEARKIHGLGDNAVVKIPMTEDGLRAIKTLSSEHINTNCTLVFNPIQALLAAKAGVTYVSPYVGRLDDIGEDGMQIIDMIRTIFNNYIIKTQILVASIRNPIHVLRSAVIGADVVTVPFNVLKSLMKHPKTDEGLAKFLEDWKKVSP 4xz9 B 1.80 BS02 G3P B 1 D6 N28 Y132 R135 S167 R169 D6 N28 Y132 R135 S167 R169 2.2.1.2 Q9HKI3 26131847 MKIFLDTANIDEIRTGVNWGIVDGVTTNPTLISKEAVNGKKYGDIIREILKIVDGPVSVQVVSTKYEGMVEEARKIHGLGDNAVVKIPMTEDGLRAIKTLSSEHINTNCTLVFNPIQALLAAKAGVTYVSPYVGRLDDIGEDGMQIIDMIRTIFNNYIIKTQILVASIRNPIHVLRSAVIGADVVTVPFNVLKSLMKHPKTDEGLAKFLEDWKKVSP 4xz9 C 1.80 BS01 PDO C 1 D6 T26 N28 K86 N108 S130 A166 D6 T26 N28 K86 N108 S130 A166 2.2.1.2 Q9HKI3 26131847 MKIFLDTANIDEIRTGVNWGIVDGVTTNPTLISKEAVNGKKYGDIIREILKIVDGPVSVQVVSTKYEGMVEEARKIHGLGDNAVVKIPMTEDGLRAIKTLSSEHINTNCTLVFNPIQALLAAKAGVTYVSPYVGRLDDIGEDGMQIIDMIRTIFNNYIIKTQILVASIRNPIHVLRSAVIGADVVTVPFNVLKSLMKHPKTDEGLAKFLEDWKKVSPDGKLIL 4xz9 C 1.80 BS02 G3P C 1 D6 Y132 R135 A166 S167 R169 D6 Y132 R135 A166 S167 R169 2.2.1.2 Q9HKI3 26131847 MKIFLDTANIDEIRTGVNWGIVDGVTTNPTLISKEAVNGKKYGDIIREILKIVDGPVSVQVVSTKYEGMVEEARKIHGLGDNAVVKIPMTEDGLRAIKTLSSEHINTNCTLVFNPIQALLAAKAGVTYVSPYVGRLDDIGEDGMQIIDMIRTIFNNYIIKTQILVASIRNPIHVLRSAVIGADVVTVPFNVLKSLMKHPKTDEGLAKFLEDWKKVSPDGKLIL 4y6d A 1.55 BS01 48U A 1 K96 E97 T98 Y99 F174 D189 A190 Q192 V213 W215 G216 G219 C220 G226 I227 Y228 K78 E79 T80 Y81 F158 D175 A176 Q178 V199 W201 G202 G204 C205 G212 I213 Y214 3.4.21.6 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y71 A 1.80 BS01 CA A 1 D70 N72 Q75 E80 D56 N58 Q61 E66 3.4.21.6 P00742 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y71 A 1.80 BS02 48W A 1 K96 E97 T98 Y99 F174 D189 A190 Q192 S195 V213 W215 G216 G219 C220 G226 I227 Y228 K82 E83 T84 Y85 F162 D179 A180 Q182 S185 V203 W205 G206 G208 C209 G216 I217 Y218 3.4.21.6 P00742 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y76 A 2.00 BS01 CA A 1 D70 N72 Q75 E80 D54 N56 Q59 E64 3.4.21.6 P00742 17338508 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y76 A 2.00 BS02 4O1 A 1 E97 Y99 F174 A190 Q192 S195 V213 W215 G216 G219 C220 G226 I227 Y228 E81 Y83 F160 A178 Q180 S183 V201 W203 G204 G206 C207 G214 I215 Y216 3.4.21.6 P00742 17338508 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y79 A 2.10 BS01 CA A 1 D70 N72 Q75 E77 E80 D56 N58 Q61 E63 E66 3.4.21.6 P00742 17338508 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y79 A 2.10 BS02 MG A 1 Y185 D185A R222 K224 Y173 D174 R211 K214 3.4.21.6 P00742 17338508 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y79 A 2.10 BS03 4O6 A 1 E97 T98 F174 A190 Q192 V213 S214 W215 G216 G219 C220 G226 I227 Y228 E83 T84 F162 A180 Q182 V203 S204 W205 G206 G208 C209 G216 I217 Y218 3.4.21.6 P00742 17338508 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y7a A 1.99 BS01 CA A 1 D70 N72 Q75 E76 E80 D56 N58 Q61 E62 E66 3.4.21.6 P00742 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y7a A 1.99 BS02 MG A 1 Y185 D185A R222 K224 Y173 D174 R211 K214 3.4.21.6 P00742 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y7a A 1.99 BS03 987 A 1 K96 E97 Y99 F174 D189 A190 Q192 S195 V213 W215 G216 G219 C220 G226 I227 Y228 K82 E83 Y85 F162 D179 A180 Q182 S185 V203 W205 G206 G208 C209 G216 I217 Y218 3.4.21.6 P00742 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y7b A 1.79 BS01 CA A 1 D70 N72 Q75 E77 E80 D56 N58 Q61 E63 E66 3.4.21.6 P00742 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4y7b A 1.79 BS02 44I A 1 K96 E97 T98 Y99 F174 D189 A190 Q192 S195 V213 W215 G216 G219 C220 G226 I227 Y228 K82 E83 T84 Y85 F162 D179 A180 Q182 S185 V203 W205 G206 G208 C209 G216 I217 Y218 3.4.21.6 P00742 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 4yfz A 1.50 BS01 GAL A 1 N155 Y156 G179 D185 R187 N92 Y93 G116 D122 R124 B6RGK2 ALDGPYTPDSSNLPSNYWYLINPLNDGVVFSVTNNSTFWMFTYLILPNTAQTNVTVNVMNETVNISIDNSGSTYRFVDYFKTSSTQSYRQRNYLITEHRLQAYRRDESGNISNYWGSSTYGDLRVGTYFNPVLNAVINLNADFYIIPDSQQEKCTEYIKGGL 4yfz A 1.50 BS02 BGC A 1 N155 R187 N92 R124 B6RGK2 ALDGPYTPDSSNLPSNYWYLINPLNDGVVFSVTNNSTFWMFTYLILPNTAQTNVTVNVMNETVNISIDNSGSTYRFVDYFKTSSTQSYRQRNYLITEHRLQAYRRDESGNISNYWGSSTYGDLRVGTYFNPVLNAVINLNADFYIIPDSQQEKCTEYIKGGL 4yg0 A 1.29 BS01 GAL A 1 N155 Y156 G179 D185 R187 N94 Y95 G118 D124 R126 B6RGK2 GSALDGPYTPDSSNLPSNYWYLINPLNDGVVFSVTNNSTFWMFTYLILPNTAQTNVTVNVMNETVNISIDNSGSTYRFVDYFKTSSTQSYRQRNYLITEHRLQAYRRDESGNISNYWGSSTYGDLRVGTYFNPVLNAVINLNADFYIIPDSQQEKCTEYIKGGL 4yg6 A 1.46 BS01 GAL A 1 N155 Y156 G179 D185 R187 N92 Y93 G116 D122 R124 P35746 SLDGPYAPDSSNLPSNCWYLVNPSNDGVVFSVTDNSTFWMFTYLVLPNTAQTNVTVNVMNETVNISIDNSGSTYRFVDYIKTSSTQAYGSRNYLNTAHRLQAYRRDGDGNISNYWGADTQGDLRVGTYSNPVPNAVINLNADFYVIPDSQQETCTEYIRGGL 4yg6 B 1.46 BS01 GAL B 1 N155 Y156 D185 R187 N93 Y94 D123 R125 P35746 GSLDGPYAPDSSNLPSNCWYLVNPSNDGVVFSVTDNSTFWMFTYLVLPNTAQTNVTVNVMNETVNISIDNSGSTYRFVDYIKTSSTQAYGSRNYLNTAHRLQAYRRDGDGNISNYWGADTQGDLRVGTYSNPVPNAVINLNADFYVIPDSQQETCTEYIRGGL 4yg6 C 1.46 BS01 GAL C 1 N155 Y156 G179 D185 R187 N93 Y94 G117 D123 R125 P35746 GSLDGPYAPDSSNLPSNCWYLVNPSNDGVVFSVTDNSTFWMFTYLVLPNTAQTNVTVNVMNETVNISIDNSGSTYRFVDYIKTSSTQAYGSRNYLNTAHRLQAYRRDGDGNISNYWGADTQGDLRVGTYSNPVPNAVINLNADFYVIPDSQQETCTEYIRGGL 4yg6 D 1.46 BS01 GAL D 1 N155 Y156 D185 R187 N93 Y94 D123 R125 P35746 GSLDGPYAPDSSNLPSNCWYLVNPSNDGVVFSVTDNSTFWMFTYLVLPNTAQTNVTVNVMNETVNISIDNSGSTYRFVDYIKTSSTQAYGSRNYLNTAHRLQAYRRDGDGNISNYWGADTQGDLRVGTYSNPVPNAVINLNADFYVIPDSQQETCTEYIRGGL 4yjo A 1.60 BS01 4DF A 1 L377 G378 A400 K402 E420 V433 M448 E449 M450 A451 G454 P455 L501 D512 L15 G16 A38 K40 E58 V71 M86 E87 M88 A89 G92 P93 L139 D150 2.7.10.2 P43405 21903390 VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD 4yjp A 1.83 BS01 4DL A 1 L377 V385 A400 K402 E420 L446 M448 E449 M450 A451 G454 P455 L501 S511 D512 L14 V22 A37 K39 E54 L80 M82 E83 M84 A85 G88 P89 L135 S145 D146 2.7.10.2 P43405 21903390 YLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD 4yjq A 1.34 BS01 4DK A 1 L377 G378 V385 A400 K402 E420 V433 L446 M448 E449 M450 A451 E452 G454 P455 K458 L501 S511 D512 L14 G15 V18 A33 K35 E53 V66 L79 M81 E82 M83 A84 E85 G87 P88 K91 L134 S144 D145 2.7.10.2 P43405 21903390 YLDRKLLTLEDKELGGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDV 4yjr A 1.32 BS01 4DJ A 1 L377 V385 A400 K402 E420 V433 L446 M448 E449 M450 A451 E452 G454 P455 L501 S511 D512 L14 V17 A32 K34 E52 V65 L78 M80 E81 M82 A83 E84 G86 P87 L133 S143 D144 2.7.10.2 P43405 21903390 YLDRKLLTLEDKELGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDV 4yjs A 2.22 BS01 4DN A 1 L377 V385 A400 K402 E420 L446 M448 E449 M450 A451 G454 P455 L501 S511 D512 L14 V17 A32 K34 E45 L71 M73 E74 M75 A76 G79 P80 L126 S136 D137 2.7.10.2 P43405 21903390 YLDRKLLTLEDKELGTVKKGYYQMKKVVKTVAVKILALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYD 4yjt A 1.52 BS01 4DQ A 1 L377 G378 V385 A400 K402 E420 V433 L446 M448 E449 M450 A451 E452 G454 P455 L501 D512 L14 G15 V22 A37 K39 E57 V70 L83 M85 E86 M87 A88 E89 G91 P92 L138 D149 2.7.10.2 P43405 21903390 YLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDV 4yju A 1.67 BS01 4DO A 1 L377 G378 V385 A400 K402 E420 V433 L446 M448 E449 M450 A451 E452 G454 P455 L501 S511 D512 L14 G15 V22 A37 K39 E57 V70 L83 M85 E86 M87 A88 E89 G91 P92 L138 S148 D149 2.7.10.2 P43405 21903390 YLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDV 4zb6 A 1.80 BS01 GDS A 1 H13 G16 P17 N18 H45 K46 R58 V59 P60 E74 S75 G116 P117 G120 W176 H10 G13 P14 N15 H42 K43 R55 V56 P57 E71 S72 G113 P114 G117 W173 26348000 HGKQFTLYTHNSGPNGWKVAIVLEELGLSYEPVFLDLMKGEHKAPEYLKINPNGRVPALIDHKNNNYTVWESNAVTQYLVDKYDNDRKISVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKIPSAIERYRNEIKRVLGVLESTLSKQEWLVGNKATVADFSFLTWNDIAANLLLENFRFEEEFPATAKWNKKLLERPAIAKVWEEKAKAAA 4zb6 A 1.80 BS02 GDS B 1 S113 R139 S110 R136 26348000 HGKQFTLYTHNSGPNGWKVAIVLEELGLSYEPVFLDLMKGEHKAPEYLKINPNGRVPALIDHKNNNYTVWESNAVTQYLVDKYDNDRKISVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKIPSAIERYRNEIKRVLGVLESTLSKQEWLVGNKATVADFSFLTWNDIAANLLLENFRFEEEFPATAKWNKKLLERPAIAKVWEEKAKAAA 4zb6 B 1.80 BS01 GDS A 1 S113 R139 S110 R136 26348000 HGKQFTLYTHNSGPNGWKVAIVLEELGLSYEPVFLDLMKGEHKAPEYLKINPNGRVPALIDHKNNNYTVWESNAVTQYLVDKYDNDRKISVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKIPSAIERYRNEIKRVLGVLESTLSKQEWLVGNKATVADFSFLTWNDIAANLLLENFRFEEEFPATAKWNKKLLERPAIAKVWEEKAKAA 4zb6 B 1.80 BS02 GDS B 1 H13 P17 N18 H45 K46 R58 V59 P60 E74 S75 G116 P117 G120 W176 H10 P14 N15 H42 K43 R55 V56 P57 E71 S72 G113 P114 G117 W173 26348000 HGKQFTLYTHNSGPNGWKVAIVLEELGLSYEPVFLDLMKGEHKAPEYLKINPNGRVPALIDHKNNNYTVWESNAVTQYLVDKYDNDRKISVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKIPSAIERYRNEIKRVLGVLESTLSKQEWLVGNKATVADFSFLTWNDIAANLLLENFRFEEEFPATAKWNKKLLERPAIAKVWEEKAKAA 4zb6 C 1.80 BS01 GDS C 1 H13 P17 N18 H45 R58 V59 P60 E74 S75 G116 P117 G120 W176 H9 P13 N14 H41 R54 V55 P56 E70 S71 G112 P113 G116 W172 26348000 GKQFTLYTHNSGPNGWKVAIVLEELGLSYEPVFLDLMKGEHKAPEYLKINPNGRVPALIDHKNNNYTVWESNAVTQYLVDKYDNDRKISVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKIPSAIERYRNEIKRVLGVLESTLSKQEWLVGNKATVADFSFLTWNDIAANLLLENFRFEEEFPATAKWNKKLLERPAIAKVWEEKAKAA 4zb6 C 1.80 BS02 GDS D 1 S113 R139 S109 R135 26348000 GKQFTLYTHNSGPNGWKVAIVLEELGLSYEPVFLDLMKGEHKAPEYLKINPNGRVPALIDHKNNNYTVWESNAVTQYLVDKYDNDRKISVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKIPSAIERYRNEIKRVLGVLESTLSKQEWLVGNKATVADFSFLTWNDIAANLLLENFRFEEEFPATAKWNKKLLERPAIAKVWEEKAKAA 4zb6 D 1.80 BS01 GDS C 1 S113 Y118 R139 S110 Y115 R136 26348000 HGKQFTLYTHNSGPNGWKVAIVLEELGLSYEPVFLDLMKGEHKAPEYLKINPNGRVPALIDHKNNNYTVWESNAVTQYLVDKYDNDRKISVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKIPSAIERYRNEIKRVLGVLESTLSKQEWLVGNKATVADFSFLTWNDIAANLLLENFRFEEEFPATAKWNKKLLERPAIAKVWEEKAKAAAH 4zb6 D 1.80 BS02 GDS D 1 P17 N18 H45 K46 R58 V59 P60 E74 S75 G116 P117 G120 W176 P14 N15 H42 K43 R55 V56 P57 E71 S72 G113 P114 G117 W173 26348000 HGKQFTLYTHNSGPNGWKVAIVLEELGLSYEPVFLDLMKGEHKAPEYLKINPNGRVPALIDHKNNNYTVWESNAVTQYLVDKYDNDRKISVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKIPSAIERYRNEIKRVLGVLESTLSKQEWLVGNKATVADFSFLTWNDIAANLLLENFRFEEEFPATAKWNKKLLERPAIAKVWEEKAKAAAH 4zb8 A 2.00 BS01 GDS A 1 G15 P16 N17 F39 H44 R57 I58 P59 E73 S74 G115 P116 G119 W175 G15 P16 N17 F39 H44 R57 I58 P59 E73 S74 G115 P116 G119 W175 26348000 MSHGKQFTLYTHKGGPNGWKVTIVLEELGLTYESIFLDFQKGEHKAPEYLKVNPNGRIPALIDHKNNDYTVWESNAIIQYLVDKYDKDRKVSVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKVPSAIERYRNEIKRVLGVLESVLSKQEFLVDGKATVADFSFLPWNEGAAKFLLEGSQFEEEFPATAKWHKKLLERPAIAKVWEERAKVS 4zb9 A 2.40 BS01 GDS A 1 H13 S16 H18 V40 A41 Q45 K46 R58 T59 P60 E74 S75 Q121 W124 Y128 H11 S14 H16 V38 A39 Q43 K44 R56 T57 P58 E72 S73 Q119 W122 Y126 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMS 4zb9 B 2.40 BS01 GDS A 1 T113 Y118 R139 T111 Y116 R137 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMS 4zb9 C 2.40 BS01 GDS D 1 T113 Y118 R139 T111 Y116 R137 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMS 4zb9 D 2.40 BS01 GDS D 1 H13 S16 H18 V40 A41 Q45 K46 R58 T59 P60 E74 S75 Q121 W124 Y128 H11 S14 H16 V38 A39 Q43 K44 R56 T57 P58 E72 S73 Q119 W122 Y126 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMS 4zba A 1.50 BS01 GDS A 1 H13 S16 H18 V40 A41 Q45 K46 R58 T59 P60 E74 S75 Q121 W124 Y128 H12 S15 H17 V39 A40 Q44 K45 R57 T58 P59 E73 S74 Q120 W123 Y127 26348000 ASHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zba A 1.50 BS02 GDS B 1 T113 Y118 R139 T112 Y117 R138 26348000 ASHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zba B 1.50 BS01 GDS A 1 T113 Y118 R139 T111 Y116 R137 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zba B 1.50 BS02 GDS B 1 H13 A15 S16 H18 V40 A41 Q45 K46 R58 T59 P60 E74 S75 Q121 W124 Y128 H11 A13 S14 H16 V38 A39 Q43 K44 R56 T57 P58 E72 S73 Q119 W122 Y126 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zba C 1.50 BS01 GDS C 1 H13 S16 H18 V40 Q45 K46 R58 T59 P60 E74 S75 Q121 W124 Y128 H12 S15 H17 V39 Q44 K45 R57 T58 P59 E73 S74 Q120 W123 Y127 26348000 ASHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zba C 1.50 BS02 GDS D 1 T113 Y118 R139 T112 Y117 R138 26348000 ASHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zba D 1.50 BS01 GDS C 1 T113 Y118 R139 T111 Y116 R137 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zba D 1.50 BS02 GDS D 1 H13 S16 H18 V40 A41 Q45 K46 R58 T59 P60 E74 S75 Q121 W124 Y128 H11 S14 H16 V38 A39 Q43 K44 R56 T57 P58 E72 S73 Q119 W122 Y126 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zbb A 1.80 BS01 GDN A 1 H13 S16 H18 V40 Q45 K46 R58 T59 P60 E74 S75 G120 V123 W176 H12 S15 H17 V39 Q44 K45 R57 T58 P59 E73 S74 G119 V122 W175 26348000 ASHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSR 4zbb A 1.80 BS02 GDN A 2 H13 A15 V40 L127 Y128 W176 M179 F183 H12 A14 V39 L126 Y127 W175 M178 F182 26348000 ASHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSR 4zbb C 1.80 BS01 GDN C 1 H13 S16 H18 V40 Q45 K46 R58 T59 P60 E74 S75 G120 V123 Y128 W176 H11 S14 H16 V38 Q43 K44 R56 T57 P58 E72 S73 G118 V121 Y126 W174 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zbb C 1.80 BS02 GDN C 2 H13 A15 W124 L127 Y128 W176 M179 F183 M220 H11 A13 W122 L125 Y126 W174 M177 F181 M218 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zbb B 1.80 BS01 GDN B 1 H13 S16 H18 V40 Q45 K46 R58 T59 P60 E74 S75 G120 V123 W176 H12 S15 H17 V39 Q44 K45 R57 T58 P59 E73 S74 G119 V122 W175 26348000 ASHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zbb B 1.80 BS02 GDN B 2 H13 K14 A15 S16 A41 W124 Y128 W176 M179 F183 R216 M220 H12 K13 A14 S15 A40 W123 Y127 W175 M178 F182 R215 M219 26348000 ASHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSRQ 4zbb D 1.80 BS01 GDN D 1 H13 S16 H18 V40 Q45 K46 R58 T59 P60 E74 S75 G120 V123 W176 H11 S14 H16 V38 Q43 K44 R56 T57 P58 E72 S73 G118 V121 W174 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSR 4zbb D 1.80 BS02 GDN D 2 H13 A15 S16 A41 Y128 W176 M179 F183 H11 A13 S14 A39 Y126 W174 M177 F181 26348000 SHDKQFSLFLHKASAHGWKVAFVLEELSLSYEIVLVDVAKNEQKSPEFMKLNPNGRTPALIDHGNSDFVIWESNAMVQYVADKYDTERKISMAPGTDDFYIQLQWQYFQGTGQGPYFGQLVWFTLYHEEKIPSAVTRYKEEALRVFSVLERVLSNQEWLVGGKMTIADISFVSWNDMIVHFLDNFDFEKEFPATAAWHYKMLKRPTIKRPWDERRKLMSR 4zbd A 1.12 BS01 GSH A 1 P16 N17 R57 G115 P116 G119 W123 W175 P15 N16 R56 G114 P115 G118 W122 W174 26348000 SHGKQFTLYTHKGGPNGWKVTIVLEELGLTYESIFLDFQKGEHKAPEYLKVNPNGRIPALIDHKNNDYTVWESNAIIQYLVDKYDKDRKVSVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKVPSAIERYRNEIKRVLGVLESVLSKQEFLVDGKATVADFSFLPWNEGAAKFLLEGSQFEEEFPATAKWHKKLLERPAIAKVWEERAKVS 4zbd A 1.12 BS02 GSH A 2 G15 P16 N17 F39 H44 G56 R57 I58 P59 E73 S74 G14 P15 N16 F38 H43 G55 R56 I57 P58 E72 S73 26348000 SHGKQFTLYTHKGGPNGWKVTIVLEELGLTYESIFLDFQKGEHKAPEYLKVNPNGRIPALIDHKNNDYTVWESNAIIQYLVDKYDKDRKVSVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKVPSAIERYRNEIKRVLGVLESVLSKQEFLVDGKATVADFSFLPWNEGAAKFLLEGSQFEEEFPATAKWHKKLLERPAIAKVWEERAKVS 4zbd A 1.12 BS03 GSH B 1 Y117 R138 Y116 R137 26348000 SHGKQFTLYTHKGGPNGWKVTIVLEELGLTYESIFLDFQKGEHKAPEYLKVNPNGRIPALIDHKNNDYTVWESNAIIQYLVDKYDKDRKVSVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKVPSAIERYRNEIKRVLGVLESVLSKQEFLVDGKATVADFSFLPWNEGAAKFLLEGSQFEEEFPATAKWHKKLLERPAIAKVWEERAKVS 4zbd B 1.12 BS01 GSH A 1 Y117 R138 Y116 R137 26348000 SHGKQFTLYTHKGGPNGWKVTIVLEELGLTYESIFLDFQKGEHKAPEYLKVNPNGRIPALIDHKNNDYTVWESNAIIQYLVDKYDKDRKVSVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKVPSAIERYRNEIKRVLGVLESVLSKQEFLVDGKATVADFSFLPWNEGAAKFLLEGSQFEEEFPATAKWHKKLLERPAIAKVWEERAKVS 4zbd B 1.12 BS02 GSH B 2 G15 P16 N17 F39 H44 G56 R57 I58 P59 E73 S74 G14 P15 N16 F38 H43 G55 R56 I57 P58 E72 S73 26348000 SHGKQFTLYTHKGGPNGWKVTIVLEELGLTYESIFLDFQKGEHKAPEYLKVNPNGRIPALIDHKNNDYTVWESNAIIQYLVDKYDKDRKVSVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKVPSAIERYRNEIKRVLGVLESVLSKQEFLVDGKATVADFSFLPWNEGAAKFLLEGSQFEEEFPATAKWHKKLLERPAIAKVWEERAKVS 4zbd B 1.12 BS03 GSH B 1 P16 N17 R57 G115 P116 G119 W123 W175 P15 N16 R56 G114 P115 G118 W122 W174 26348000 SHGKQFTLYTHKGGPNGWKVTIVLEELGLTYESIFLDFQKGEHKAPEYLKVNPNGRIPALIDHKNNDYTVWESNAIIQYLVDKYDKDRKVSVAPGTNEYYTQLQWLYFQASGQGPYYGQAAWFSVYHPEKVPSAIERYRNEIKRVLGVLESVLSKQEFLVDGKATVADFSFLPWNEGAAKFLLEGSQFEEEFPATAKWHKKLLERPAIAKVWEERAKVS 4zgn A 2.90 BS01 ATP A 1 V94 K96 W99 S100 T101 K103 L114 K164 E165 W166 F167 M169 E174 R176 R190 I238 D239 N241 V83 K85 W88 S89 T90 K92 L103 K150 E151 W152 F153 M155 E160 R162 R176 I224 D225 N227 Q9P7N5 26211610 LVPRGSHMTLILTKNQVLHCQFSSWYSLFRKLTPKAKVIKPIPATVLKYLHEDSIYVEQAYYPEREAIQLIEKAIKELGGAVVPKLNWSTPKDALWITTTGSLKCTTAEEVLLLLKSSDFVAHDLNHAFDDCKDFDNADPKDFSFELVLKEWFPMHASTEFRCFVKSKRLIAFCQRDDNYYEFLKENIDCYEKLISDLLKKLDTFPDPDFVFDVYIHKDRAWLIDINPFYPRTDGLLFSWSELESMNSENMKPEIRLIPKASEGENLLEFAQKWQDLTN 4zgn A 2.90 BS02 MG A 1 W99 D239 N241 W88 D225 N227 Q9P7N5 26211610 LVPRGSHMTLILTKNQVLHCQFSSWYSLFRKLTPKAKVIKPIPATVLKYLHEDSIYVEQAYYPEREAIQLIEKAIKELGGAVVPKLNWSTPKDALWITTTGSLKCTTAEEVLLLLKSSDFVAHDLNHAFDDCKDFDNADPKDFSFELVLKEWFPMHASTEFRCFVKSKRLIAFCQRDDNYYEFLKENIDCYEKLISDLLKKLDTFPDPDFVFDVYIHKDRAWLIDINPFYPRTDGLLFSWSELESMNSENMKPEIRLIPKASEGENLLEFAQKWQDLTN 4zjz A 1.70 BS01 OOB A 1 A227 Y228 A302 G303 E304 A305 D324 G325 I326 G327 S328 T329 L332 H333 I334 S404 D406 Y418 R421 K427 Y432 A222 Y223 A297 G298 E299 A300 D319 G320 I321 G322 S323 T324 L327 H328 I329 S399 D401 Y413 R416 K422 Y427 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGV 4zjz A 1.70 BS02 BEZ A 1 A221 P251 V256 F272 G274 A275 G278 M282 A216 P246 V251 F267 G269 A270 G273 M277 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGV 4zjz B 1.70 BS01 BEZ B 1 A221 P251 V256 F272 G274 A275 G278 M282 A216 P246 V251 F267 G269 A270 G273 M277 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVLG 4zjz B 1.70 BS02 OOB B 1 A227 Y228 A302 G303 E304 A305 D324 G325 I326 G327 S328 T329 L332 H333 I334 D406 Y418 R421 K427 Y432 A222 Y223 A297 G298 E299 A300 D319 G320 I321 G322 S323 T324 L327 H328 I329 D401 Y413 R416 K422 Y427 Q93TK0 VTPPPEKFNFAEHLLQTNRVRPDKTAFVDDISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTADDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAPLEPGEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNTLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERPTPDAVFKRWLGGVGGVKPTVFYGAPTGYAGMLAAPNLPSRDQVALRLASSAGEALPAEIGQRFQRHFGLDIVDGIGSTEMLHIFLSNLPDRVRYGTTGWPVPGYQIELRGDGGGPVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRNDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGLTKPKAYVVPRPGQTLSETELKTFIKDRLAPYKYPRSTVFVAELPKTATGKIQRFKLREGVLG 4zkh A 1.90 BS01 FE A 1 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh A 1.90 BS02 FE A 2 E48 H51 E94 N97 Q127 E130 E48 H51 E94 N97 Q127 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh A 1.90 BS03 FE A 3 D30 E35 D30 E35 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh D 1.90 BS01 FE D 1 E48 E94 N97 Q127 E130 E48 E94 N97 Q127 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh D 1.90 BS02 FE D 2 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh D 1.90 BS03 FE D 3 D30 E35 D30 E35 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh B 1.90 BS01 FE B 1 E48 H51 E94 N97 Q127 E130 E48 H51 E94 N97 Q127 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh B 1.90 BS02 FE B 2 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh B 1.90 BS03 FE B 3 E47 Q126 E47 Q126 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh B 1.90 BS04 FE B 4 D30 E35 D30 E35 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh B 1.90 BS05 FE B 5 E47 E50 E47 E50 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh C 1.90 BS01 FE C 1 E48 H51 E94 N97 Q127 E130 E47 H50 E93 N96 Q126 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh C 1.90 BS02 FE C 2 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh C 1.90 BS03 FE C 3 D30 E35 D29 E34 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh E 1.90 BS01 FE E 1 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh E 1.90 BS02 FE E 2 E48 H51 E94 N97 Q127 E130 E48 H51 E94 N97 Q127 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh E 1.90 BS03 FE E 3 D30 E35 D30 E35 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh E 1.90 BS04 FE E 4 E47 E50 E47 E50 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh F 1.90 BS01 FE F 1 Q44 E48 H51 E94 N97 Q127 E130 Q44 E48 H51 E94 N97 Q127 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh F 1.90 BS02 FE F 2 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh F 1.90 BS03 FE F 3 D30 E35 D30 E35 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh G 1.90 BS01 FE G 1 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh G 1.90 BS02 FE G 2 E48 H51 E94 N97 Q127 E130 E47 H50 E93 N96 Q126 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh G 1.90 BS03 FE G 3 D30 E35 D29 E34 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkh H 1.90 BS01 FE H 1 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh H 1.90 BS02 FE H 2 E48 H51 E94 N97 Q127 E130 E48 H51 E94 N97 Q127 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkh H 1.90 BS03 FE H 3 D30 E35 D30 E35 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw A 1.80 BS01 FE A 1 Q44 E48 E94 N97 E130 Q43 E47 E93 N96 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkw A 1.80 BS02 FE A 2 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkw D 1.80 BS01 FE D 1 E15 E48 H51 N97 Q127 E14 E47 H50 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw D 1.80 BS02 FE D 2 Y22 Q44 E48 E94 N97 E130 Y21 Q43 E47 E93 N96 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw B 1.80 BS01 FE B 1 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw B 1.80 BS02 FE B 2 E48 E94 N97 Q127 E48 E94 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw C 1.80 BS01 FE C 1 E48 E94 N97 Q127 E47 E93 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkw C 1.80 BS02 FE C 2 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkw E 1.80 BS01 FE E 1 E48 E94 N97 Q127 E47 E93 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkw E 1.80 BS02 FE E 2 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkw F 1.80 BS01 FE F 1 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw F 1.80 BS02 FE F 2 E48 E94 N97 Q127 E130 E47 E93 N96 Q126 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw G 1.80 BS01 FE G 1 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw G 1.80 BS02 FE G 2 E48 E94 N97 Q127 E47 E93 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw H 1.80 BS01 FE H 1 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkw H 1.80 BS02 FE H 2 E48 E94 N97 Q127 E48 E94 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkx A 1.80 BS01 FE A 1 E15 E48 H51 E14 E47 H50 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkx D 1.80 BS01 FE D 1 E15 E48 H51 E14 E47 H50 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkx B 1.80 BS01 FE B 1 E15 E48 H51 E15 E48 H51 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkx C 1.80 BS01 FE C 1 E15 E48 H51 E14 E47 H50 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkx E 1.80 BS01 FE E 1 E15 E48 H51 E14 E47 H50 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zkx F 1.80 BS01 FE F 1 E15 E48 H51 E14 E47 H50 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkx G 1.80 BS01 FE G 1 E15 E48 H51 E14 E47 H50 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zkx H 1.80 BS01 FE H 1 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAQSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zl5 B 1.85 BS01 FE B 1 E47 H51 Q126 E130 E47 H51 Q126 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 B 1.85 BS02 FE B 2 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 B 1.85 BS03 FE B 3 H44 E48 E94 E130 H44 E48 E94 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 B 1.85 BS04 FE B 4 E3 D6 R10 E3 D6 R10 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 B 1.85 BS05 FE B 5 E2 D6 E2 D6 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 A 1.85 BS01 FE A 1 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 A 1.85 BS02 FE A 2 H44 E48 E94 E130 H44 E48 E94 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 A 1.85 BS03 FE A 3 E47 H51 Q126 E130 E47 H51 Q126 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 C 1.85 BS01 FE C 1 H44 E47 E48 E94 E130 H43 E46 E47 E93 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 C 1.85 BS02 FE C 2 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 C 1.85 BS03 FE C 3 E47 H51 Q126 E130 E46 H50 Q125 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 D 1.85 BS01 FE D 1 H44 E48 E94 E130 H44 E48 E94 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 D 1.85 BS02 FE D 2 E47 H51 Q126 E130 E47 H51 Q126 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 D 1.85 BS03 FE D 3 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 E 1.85 BS01 FE E 1 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 E 1.85 BS02 FE E 2 H44 E48 E94 E130 H44 E48 E94 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 E 1.85 BS03 FE E 3 E47 H51 Q126 E130 E47 H51 Q126 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 E 1.85 BS04 FE E 4 E2 D6 E2 D6 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 E 1.85 BS05 FE E 5 E2 D6 E2 D6 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl5 F 1.85 BS01 FE F 1 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zl5 F 1.85 BS02 FE F 2 Y22 H44 E48 E94 E130 Y22 H44 E48 E94 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zl5 F 1.85 BS03 FE F 3 E47 H51 Q126 E130 E47 H51 Q126 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zl6 B 1.90 BS01 FE B 1 E47 H51 Q126 E130 E47 H51 Q126 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 B 1.90 BS02 FE B 2 H44 E48 E94 E130 H44 E48 E94 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 B 1.90 BS03 FE B 3 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 B 1.90 BS04 FE B 4 E3 D6 R10 E3 D6 R10 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 B 1.90 BS05 FE B 5 E2 E3 E2 E3 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 B 1.90 BS06 FE B 6 E2 D6 E2 D6 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 A 1.90 BS01 FE A 1 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 A 1.90 BS02 FE A 2 H44 E48 E94 E130 H43 E47 E93 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 A 1.90 BS03 FE A 3 E47 H51 Q126 E130 E46 H50 Q125 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 C 1.90 BS01 FE C 1 E47 H51 Q126 E130 E47 H51 Q126 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 C 1.90 BS02 FE C 2 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 C 1.90 BS03 FE C 3 H44 E47 E48 E94 E130 H44 E47 E48 E94 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 D 1.90 BS01 FE D 1 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 D 1.90 BS02 FE D 2 E47 H51 Q126 E130 E47 H51 Q126 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 D 1.90 BS03 FE D 3 H44 E48 E94 E130 H44 E48 E94 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 E 1.90 BS01 FE E 1 E47 H51 Q126 E130 E47 H51 Q126 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 E 1.90 BS02 FE E 2 H44 E48 E94 E130 H44 E48 E94 E130 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 E 1.90 BS03 FE E 3 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 E 1.90 BS04 FE E 4 E2 D6 E2 D6 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 E 1.90 BS05 FE E 5 E2 D6 E2 D6 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVS 4zl6 F 1.90 BS01 FE F 1 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zl6 F 1.90 BS02 FE F 2 H44 E48 E94 E130 H43 E47 E93 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zl6 F 1.90 BS03 FE F 3 E47 H51 Q126 E130 E46 H50 Q125 E129 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAHSAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw A 2.00 BS01 FE A 1 E15 E48 H51 N97 Q127 E14 E47 H50 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw A 2.00 BS02 FE A 2 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw A 2.00 BS03 FE A 3 Y40 E44 K133 Y39 E43 K132 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw A 2.00 BS04 FE A 4 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw D 2.00 BS01 FE D 1 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw D 2.00 BS02 FE D 2 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw D 2.00 BS03 FE D 3 E48 E94 N97 Q127 E47 E93 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw D 2.00 BS04 FE D 4 Y40 E44 Y39 E43 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw D 2.00 BS05 FE D 5 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw B 2.00 BS01 FE B 1 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw B 2.00 BS02 FE B 2 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw B 2.00 BS03 FE B 3 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw B 2.00 BS04 FE B 4 E48 E94 N97 Q127 E47 E93 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw B 2.00 BS05 FE B 5 Y40 E44 K133 Y39 E43 K132 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw C 2.00 BS01 FE C 1 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw C 2.00 BS02 FE C 2 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw C 2.00 BS03 FE C 3 E48 E94 N97 Q127 E47 E93 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw C 2.00 BS04 FE C 4 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw E 2.00 BS01 FE E 1 E44 E47 E44 E47 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw E 2.00 BS02 FE E 2 E15 E48 H51 N97 E15 E48 H51 N97 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw E 2.00 BS03 FE E 3 E48 E94 N97 Q127 E48 E94 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw E 2.00 BS04 FE E 4 Y40 E44 Y40 E44 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw F 2.00 BS01 FE F 1 Y40 E44 K133 Y39 E43 K132 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw F 2.00 BS02 FE F 2 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw F 2.00 BS03 FE F 3 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw F 2.00 BS04 FE F 4 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw F 2.00 BS05 FE F 5 E48 E94 N97 Q127 E47 E93 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw G 2.00 BS01 FE G 1 E15 E48 H51 N97 E13 E46 H49 N95 1.16.3.1 B6DMH6 ELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw G 2.00 BS02 FE G 2 E44 E47 E42 E45 1.16.3.1 B6DMH6 ELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw G 2.00 BS03 FE G 3 E48 E94 N97 Q127 E46 E92 N95 Q125 1.16.3.1 B6DMH6 ELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw G 2.00 BS04 FE G 4 E44 E47 E42 E45 1.16.3.1 B6DMH6 ELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw G 2.00 BS05 FE G 5 Y40 E44 K133 Y38 E42 K131 1.16.3.1 B6DMH6 ELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zlw H 2.00 BS01 FE H 1 E15 E48 H51 N97 E14 E47 H50 N96 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw H 2.00 BS02 FE H 2 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw H 2.00 BS03 FE H 3 Y40 E44 Y39 E43 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zlw H 2.00 BS04 FE H 4 E44 E47 E43 E46 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zmc A 1.90 BS01 FE A 1 E15 E48 H51 N97 Q127 E14 E47 H50 N96 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVS 4zmc D 1.90 BS01 FE D 1 E15 E48 H51 E14 E47 H50 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zmc C 1.90 BS01 FE C 1 E15 E48 H51 Q127 E15 E48 H51 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVV 4zmc E 1.90 BS01 FE E 1 E15 E48 H51 Q127 E14 E47 H50 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zmc F 1.90 BS01 FE F 1 E15 E48 H51 Q127 E14 E47 H50 Q126 1.16.3.1 B6DMH6 EELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zmc G 1.90 BS01 FE G 1 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLDVVSF 4zmc H 1.90 BS01 FE H 1 E15 E48 H51 N97 Q127 E15 E48 H51 N97 Q127 1.16.3.1 B6DMH6 SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEEREHGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRSLLNLAEAASTCHDFAVMAFLNPFHLQQVNAEDKIGSILAKVTDENRTPGLLRSLD 5a7b A 1.40 BS01 ZN A 1 C176 H179 C238 C242 C81 H84 C143 C147 P04637 26378745 SVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKLFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPCEPPEVGSDCTTIHYNYMCYSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENLRK 5a7b A 1.40 BS02 KMN A 1 L145 V147 D148 T150 P151 P152 C220 E221 P222 P223 T230 L50 V52 D53 T55 P56 P57 C125 E126 P127 P128 T135 P04637 26378745 SVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKLFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPCEPPEVGSDCTTIHYNYMCYSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENLRK 5a7b B 1.40 BS01 ZN B 1 C176 H179 C238 C242 C83 H86 C145 C149 P04637 26378745 SSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKLFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPCEPPEVGSDCTTIHYNYMCYSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENLR 5a7b B 1.40 BS02 KMN B 1 L145 V147 D148 T150 P151 P152 C220 E221 P222 P223 L52 V54 D55 T57 P58 P59 C127 E128 P129 P130 P04637 26378745 SSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKLFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPCEPPEVGSDCTTIHYNYMCYSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENLR 5a8e A 2.40 BS01 XTK A 1 W117 T118 D121 V122 T203 Y207 A208 S211 S215 W303 F306 F307 N310 N329 Y333 W82 T83 D86 V87 T168 Y172 A173 S176 S180 W234 F237 F238 N241 N260 Y264 P07700 26385885 LSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASVWTLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRKRKTSRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIILCRSPDFRKAFK 5a8e A 2.40 BS02 MHA A 1 G110 S111 P196 G75 S76 P161 P07700 26385885 LSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASVWTLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQIRKRKTSRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIILCRSPDFRKAFK 5ab0 A 2.50 BS01 III E 1 E200 P201 G334 A335 E337 R345 D360 W363 V367 H370 E371 H374 E393 F450 Y455 K756 K792 N822 L825 Y826 A857 A861 R864 Y892 M896 E147 P148 G281 A282 E284 R292 D307 W310 V314 H317 E318 H321 E340 F397 Y402 K703 K739 N769 L772 Y773 A804 A808 R811 Y839 M843 3.4.11.1,3.4.11.6 Q6P179 26381406 PVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTRHH 5ab0 A 2.50 BS02 ZN A 1 H370 H374 E393 H317 H321 E340 3.4.11.1,3.4.11.6 Q6P179 26381406 PVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTRHH 5ab0 C 2.50 BS01 III F 1 E200 P201 G334 A335 M336 E337 R345 T347 S359 D360 W363 V367 H370 E371 H374 E393 F450 D451 Y455 N822 Y826 A857 A861 R864 Y892 E147 P148 G281 A282 M283 E284 R292 T294 S306 D307 W310 V314 H317 E318 H321 E340 F397 D398 Y402 N742 Y746 A777 A781 R784 Y812 3.4.11.1,3.4.11.6 Q6P179 26381406 PVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTR 5ab0 C 2.50 BS02 ZN C 1 H370 H374 E393 H317 H321 E340 3.4.11.1,3.4.11.6 Q6P179 26381406 PVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTR 5ab2 A 2.73 BS01 III C 1 E200 P333 G334 A335 E337 T347 S348 W363 V367 H370 E371 H374 K392 E393 F450 D451 Y455 N822 E147 P280 G281 A282 E284 T294 S295 W310 V314 H317 E318 H321 K339 E340 F397 D398 Y402 N757 3.4.11.- Q6P179 26381406 PVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTR 5ab2 A 2.73 BS02 ZN A 1 H370 H374 E393 H317 H321 E340 3.4.11.- Q6P179 26381406 PVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTR 5ab2 B 2.73 BS01 III D 1 E200 P333 A335 M336 E337 R345 D360 W363 H370 E371 H374 E393 F450 D451 E452 Y455 Y892 E147 P280 A282 M283 E284 R292 D307 W310 H317 E318 H321 E340 F397 D398 E399 Y402 Y810 3.4.11.- Q6P179 26381406 PVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 5ab2 B 2.73 BS02 ZN B 1 H370 H374 E393 H317 H321 E340 3.4.11.- Q6P179 26381406 PVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 5amv A 1.57 BS01 CA A 1 D184 D223 D227 D184 D223 D227 P39116 ADLGHQTLGSNDGWGAYSTGTTGGSKASSSNVYTVSNRNQLVSALGKETNTTPKIIYIKGTIDMNVDDNLKPLGLNDYKDPEYDLDKYLKAYDPSTWGKKEPSGTQEEARARSQKNQKARVMVDIPANTTIVGSGTNAKVVGGNFQIKSDNVIIRNIEFQDAYDYFPQWDPTDGSSGNWNSQYDNITINGGTHIWIDHCTFNDGSRPDSTSPKYYGRKYQHHDGQTDASNGANYITMSYNYYHDHDKSSIFGSSDSKTSDDGKLKITLHHNRYKNIVQRAPRVRFGQVHVYNNYYEGSTSSSSYPFSYAWGIGKSSKIYAQNNVIDVPGLSAAKTISVFSGGTALYDSGTLLNGTQINASAANGLSSSVGWTPSLHGSIDASANVKSNVINQAGAGKLN 5amv A 1.57 BS02 ADA A 1 D173 G174 N178 R279 R282 F339 D173 G174 N178 R279 R282 F339 P39116 ADLGHQTLGSNDGWGAYSTGTTGGSKASSSNVYTVSNRNQLVSALGKETNTTPKIIYIKGTIDMNVDDNLKPLGLNDYKDPEYDLDKYLKAYDPSTWGKKEPSGTQEEARARSQKNQKARVMVDIPANTTIVGSGTNAKVVGGNFQIKSDNVIIRNIEFQDAYDYFPQWDPTDGSSGNWNSQYDNITINGGTHIWIDHCTFNDGSRPDSTSPKYYGRKYQHHDGQTDASNGANYITMSYNYYHDHDKSSIFGSSDSKTSDDGKLKITLHHNRYKNIVQRAPRVRFGQVHVYNNYYEGSTSSSSYPFSYAWGIGKSSKIYAQNNVIDVPGLSAAKTISVFSGGTALYDSGTLLNGTQINASAANGLSSSVGWTPSLHGSIDASANVKSNVINQAGAGKLN 5amv A 1.57 BS03 ADA A 2 R217 Q278 F339 R217 Q278 F339 P39116 ADLGHQTLGSNDGWGAYSTGTTGGSKASSSNVYTVSNRNQLVSALGKETNTTPKIIYIKGTIDMNVDDNLKPLGLNDYKDPEYDLDKYLKAYDPSTWGKKEPSGTQEEARARSQKNQKARVMVDIPANTTIVGSGTNAKVVGGNFQIKSDNVIIRNIEFQDAYDYFPQWDPTDGSSGNWNSQYDNITINGGTHIWIDHCTFNDGSRPDSTSPKYYGRKYQHHDGQTDASNGANYITMSYNYYHDHDKSSIFGSSDSKTSDDGKLKITLHHNRYKNIVQRAPRVRFGQVHVYNNYYEGSTSSSSYPFSYAWGIGKSSKIYAQNNVIDVPGLSAAKTISVFSGGTALYDSGTLLNGTQINASAANGLSSSVGWTPSLHGSIDASANVKSNVINQAGAGKLN 5bv9 A 1.93 BS01 CA A 1 Q181 E186 D405 Q180 E185 D404 3.2.1.91 A8FDC4 SNKERFLTLYHQIKSDANGYFSPEGIPYHSIETLICEAPDYGHMTTSEAYSYWLWLEVLYGHYTRDWSKLEAAWDNMEKYIIPVNEDGNDEQPHMSAYNPSSPATYASEKPYPDQYPSQLSGARPAGQDPIDGELKSTYGTNETYLMHWLLDVDNWYKYGNLLNPSHKAAYVNTFQRGQQESVWEAIPHPSQDDKSFGKPNEGFMSLFTKENQVPAAQWRYTNATDADARAIQAIYWAKELGYNNSTYLDKAKKMGDFLRYGMYDKYFQTIGSGKQGNPYPGNGKGACHYLMAWYTSWGGGLGDYANWSWRIGASHCHQGYQNPVAAYALSSDKGGLKPSSATGASDWEKTLKRQLEFYVWLQSKEGAIAGGATNSWNGDYSAYPAGRSTFYDMAYEDAPVYHDPPSNNWFGMQAWPMERVAELYYIFVKDGDKTSENVQMAKSCITKWVNYALDYIFIGSRPVSDEEGYFLDDQGRRILGGTNATVATTSAPGEFWLPGNIAWSGQPDTWNGFQSATGNPNLTAVTKDPTQDTGVLGSLVKAFTFFAAATKLETGNYTALGVRAKDAAAQLLEVAWNYNDGVGIVTEEEREDYDRFFKKEVYFPNGWNGTFGQGNQIPGSSTIPSDPQRGGNGVYTSFADLRPNIKQDPAWSSLESKYQSSFNEATGKWENGAPVFTYHRFWSQVDMATAYAEYHRLINL 5bv9 A 1.93 BS02 CA A 2 E79 K80 I83 V85 E92 E78 K79 I82 V84 E91 3.2.1.91 A8FDC4 SNKERFLTLYHQIKSDANGYFSPEGIPYHSIETLICEAPDYGHMTTSEAYSYWLWLEVLYGHYTRDWSKLEAAWDNMEKYIIPVNEDGNDEQPHMSAYNPSSPATYASEKPYPDQYPSQLSGARPAGQDPIDGELKSTYGTNETYLMHWLLDVDNWYKYGNLLNPSHKAAYVNTFQRGQQESVWEAIPHPSQDDKSFGKPNEGFMSLFTKENQVPAAQWRYTNATDADARAIQAIYWAKELGYNNSTYLDKAKKMGDFLRYGMYDKYFQTIGSGKQGNPYPGNGKGACHYLMAWYTSWGGGLGDYANWSWRIGASHCHQGYQNPVAAYALSSDKGGLKPSSATGASDWEKTLKRQLEFYVWLQSKEGAIAGGATNSWNGDYSAYPAGRSTFYDMAYEDAPVYHDPPSNNWFGMQAWPMERVAELYYIFVKDGDKTSENVQMAKSCITKWVNYALDYIFIGSRPVSDEEGYFLDDQGRRILGGTNATVATTSAPGEFWLPGNIAWSGQPDTWNGFQSATGNPNLTAVTKDPTQDTGVLGSLVKAFTFFAAATKLETGNYTALGVRAKDAAAQLLEVAWNYNDGVGIVTEEEREDYDRFFKKEVYFPNGWNGTFGQGNQIPGSSTIPSDPQRGGNGVYTSFADLRPNIKQDPAWSSLESKYQSSFNEATGKWENGAPVFTYHRFWSQVDMATAYAEYHRLINL 5bv9 A 1.93 BS03 CA A 3 N246 T248 N245 T247 3.2.1.91 A8FDC4 SNKERFLTLYHQIKSDANGYFSPEGIPYHSIETLICEAPDYGHMTTSEAYSYWLWLEVLYGHYTRDWSKLEAAWDNMEKYIIPVNEDGNDEQPHMSAYNPSSPATYASEKPYPDQYPSQLSGARPAGQDPIDGELKSTYGTNETYLMHWLLDVDNWYKYGNLLNPSHKAAYVNTFQRGQQESVWEAIPHPSQDDKSFGKPNEGFMSLFTKENQVPAAQWRYTNATDADARAIQAIYWAKELGYNNSTYLDKAKKMGDFLRYGMYDKYFQTIGSGKQGNPYPGNGKGACHYLMAWYTSWGGGLGDYANWSWRIGASHCHQGYQNPVAAYALSSDKGGLKPSSATGASDWEKTLKRQLEFYVWLQSKEGAIAGGATNSWNGDYSAYPAGRSTFYDMAYEDAPVYHDPPSNNWFGMQAWPMERVAELYYIFVKDGDKTSENVQMAKSCITKWVNYALDYIFIGSRPVSDEEGYFLDDQGRRILGGTNATVATTSAPGEFWLPGNIAWSGQPDTWNGFQSATGNPNLTAVTKDPTQDTGVLGSLVKAFTFFAAATKLETGNYTALGVRAKDAAAQLLEVAWNYNDGVGIVTEEEREDYDRFFKKEVYFPNGWNGTFGQGNQIPGSSTIPSDPQRGGNGVYTSFADLRPNIKQDPAWSSLESKYQSSFNEATGKWENGAPVFTYHRFWSQVDMATAYAEYHRLINL 5bv9 A 1.93 BS04 CBI A 1 H30 E38 A39 W411 W417 D534 R682 W684 H29 E37 A38 W410 W416 D533 R681 W683 3.2.1.91 A8FDC4 SNKERFLTLYHQIKSDANGYFSPEGIPYHSIETLICEAPDYGHMTTSEAYSYWLWLEVLYGHYTRDWSKLEAAWDNMEKYIIPVNEDGNDEQPHMSAYNPSSPATYASEKPYPDQYPSQLSGARPAGQDPIDGELKSTYGTNETYLMHWLLDVDNWYKYGNLLNPSHKAAYVNTFQRGQQESVWEAIPHPSQDDKSFGKPNEGFMSLFTKENQVPAAQWRYTNATDADARAIQAIYWAKELGYNNSTYLDKAKKMGDFLRYGMYDKYFQTIGSGKQGNPYPGNGKGACHYLMAWYTSWGGGLGDYANWSWRIGASHCHQGYQNPVAAYALSSDKGGLKPSSATGASDWEKTLKRQLEFYVWLQSKEGAIAGGATNSWNGDYSAYPAGRSTFYDMAYEDAPVYHDPPSNNWFGMQAWPMERVAELYYIFVKDGDKTSENVQMAKSCITKWVNYALDYIFIGSRPVSDEEGYFLDDQGRRILGGTNATVATTSAPGEFWLPGNIAWSGQPDTWNGFQSATGNPNLTAVTKDPTQDTGVLGSLVKAFTFFAAATKLETGNYTALGVRAKDAAAQLLEVAWNYNDGVGIVTEEEREDYDRFFKKEVYFPNGWNGTFGQGNQIPGSSTIPSDPQRGGNGVYTSFADLRPNIKQDPAWSSLESKYQSSFNEATGKWENGAPVFTYHRFWSQVDMATAYAEYHRLINL 5byj A 1.80 BS01 A3P A 1 R17 T18 G19 T20 K21 S22 R115 S123 L203 P225 C226 V227 N228 S229 H230 R19 T20 G21 T22 K23 S24 R114 S122 L202 P224 C225 V226 N227 S228 H229 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTLTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDLI 5byj A 1.80 BS02 OQR A 1 M38 F39 I42 D91 L92 V128 I140 D144 F153 T157 M233 L236 T237 M40 F41 I44 D90 L91 V127 I139 D143 F152 T156 M232 L235 T236 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTLTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDLI 5byk A 1.28 BS01 A3P A 1 R17 T18 G19 T20 K21 S22 R115 S123 L203 P225 C226 V227 N228 S229 H230 R19 T20 G21 T22 K23 S24 R112 S120 L200 P222 C223 V224 N225 S226 H227 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDLI 5byk A 1.28 BS02 OAQ A 1 P16 M38 D91 L92 V127 V128 D144 L147 F153 T157 T237 P18 M40 D88 L89 V124 V125 D141 L144 F150 T154 T234 G4VLE5 GAMIESSTTIQVISAGLPRTGTKSLKNALEIIYHKPCYHMFEIIFNKQSDIIKWQNLIHDSHMITTTKTIAIYDKLKELLDGYIATTDLPTCGFYKDLMNIYPNAKVLLTIRDKYDWLHSLRKVVLPKSNDPWKLKIEEGDKVLGLNSDFYKLTEDSLKFAFQKDDLNFDDDQVLLECYDEYNRLVQETVPSDRLLVLRLGDGWEPLCKFLNVEIPNGIDYPCVNSHHQMTQLTEQLIKYKSLDAIIHMFPDLI 5c1w A 1.70 BS01 ZN A 1 H519 H553 D554 D664 H83 H117 D118 D228 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEET 5c1w A 1.70 BS02 4XS A 1 L665 V668 Y683 M703 Q716 F719 L229 V232 Y247 M267 Q280 F283 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEET 5c1w B 1.70 BS01 ZN B 1 H519 H553 D554 D664 H84 H118 D119 D218 3.1.4.17,3.1.4.35 Q9Y233 26378882 SHMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5c28 A 1.56 BS01 ZN A 1 H519 H553 D554 D664 H83 H117 D118 D228 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEET 5c28 A 1.56 BS02 4XV A 1 L665 V668 I682 Y683 M703 Q716 F719 L229 V232 I246 Y247 M267 Q280 F283 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEET 5c28 B 1.56 BS01 ZN B 1 H519 H553 D554 D664 H83 H117 D118 D215 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWIS 5c29 A 2.05 BS01 ZN A 1 H519 H553 D554 D664 H66 H100 D101 D211 3.1.4.17,3.1.4.35 Q9Y233 26378882 LPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5c29 A 2.05 BS02 4XY A 1 H515 V668 I682 Y683 F686 M703 Q716 F719 H62 V215 I229 Y230 F233 M250 Q263 F266 3.1.4.17,3.1.4.35 Q9Y233 26378882 LPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 5c29 B 2.05 BS01 ZN B 1 H519 H553 D554 D664 H60 H94 D95 D193 3.1.4.17,3.1.4.35 Q9Y233 26378882 CKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5c2a A 2.00 BS01 ZN A 1 H519 H553 D554 D664 H83 H117 D118 D228 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5c2a A 2.00 BS02 4Y2 A 1 Y514 H515 L665 S667 V668 I682 Y683 F686 M703 Q716 F719 Y78 H79 L229 S231 V232 I246 Y247 F250 M267 Q280 F283 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5c2a B 2.00 BS01 ZN B 1 H519 H553 D554 D664 H83 H117 D118 D228 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5c2a B 2.00 BS02 4Y2 B 1 Y514 H515 L665 V668 I682 Y683 F686 M703 Q716 F719 Y78 H79 L229 V232 I246 Y247 F250 M267 Q280 F283 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5c5t A 1.60 BS01 AKG A 1 Y129 Y135 H138 D140 M158 T172 H207 G209 K217 I219 N221 W223 Y83 Y89 H92 D94 M112 T126 H161 G163 K171 I173 N175 W177 Q84406 26368022 GVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIPKSRNSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAV 5c5t A 1.60 BS02 ZN A 1 H138 D140 H207 H92 D94 H161 Q84406 26368022 GVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIPKSRNSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAV 5c5t A 1.60 BS03 MN A 1 D34 H114 D4 H68 Q84406 26368022 GVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIPKSRNSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAV 5c5t B 1.60 BS01 AKG B 1 Y129 Y135 H138 D140 M158 T172 H207 G209 K217 I219 N221 W223 Y80 Y86 H89 D91 M109 T123 H158 G160 K168 I170 N172 W174 Q84406 26368022 GVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIRNSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAVK 5c5t B 1.60 BS02 ZN B 1 H138 D140 H207 H89 D91 H158 Q84406 26368022 GVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIRNSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAVK 5c5u A 1.70 BS01 MN A 1 H152 D154 H221 H98 D100 H167 Q84406 26368022 HMEGFETSDRPGVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIKEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAV 5c5u B 1.70 BS01 MN B 1 H152 D154 H221 H100 D102 H169 Q84406 26368022 SHMEGFETSDRPGVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIKSEQTWFMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEEGGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRAVK 5c7r A 1.94 BS01 MLR A 1 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 Y341 R344 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 Y341 R344 P19614 26371748 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAANQASVVANQLIPINTALTLVMMRSEVVTPVGIPAEDIPRLVSMQVNRAVPLGTTLMPDMVKGYAA 5c7r B 1.94 BS01 MLR B 1 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 M330 W340 Y341 R344 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 M330 W340 Y341 R344 P19614 26371748 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAANQASVVANQLIPINTALTLVMMRSEVVTPVGIPAEDIPRLVSMQVNRAVPLGTTLMPDMVKGYAA 5c8a A 2.15 BS01 B12 A 1 L121 L124 R125 G128 E129 W131 H132 E141 H142 S145 G174 E175 R176 H177 E178 I179 G180 V220 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L41 L44 R45 G48 E49 W51 H52 E61 H62 S65 G94 E95 R96 H97 E98 I99 G100 V140 S142 V144 L145 G167 G168 Q169 M184 D186 L187 Q746J7 EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 5c8a B 2.15 BS01 B12 B 1 L121 L124 R125 G128 W131 H132 E141 H142 S145 R149 G174 E175 R176 H177 E178 I179 G180 L183 V220 L221 S222 V224 L225 G247 G248 Q249 M264 L267 L39 L42 R43 G46 W49 H50 E59 H60 S63 R67 G92 E93 R94 H95 E96 I97 G98 L101 V138 L139 S140 V142 L143 G165 G166 Q167 M182 L185 Q746J7 LGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8a C 2.15 BS01 B12 C 1 L121 L124 R125 G128 W131 E141 H142 S145 G174 E175 R176 H177 E178 I179 G180 V220 L221 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L42 L45 R46 G49 W52 E62 H63 S66 G95 E96 R97 H98 E99 I100 G101 V141 L142 S143 V145 L146 G168 G169 Q170 M185 D187 L188 Q746J7 PEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 5c8a D 2.15 BS01 B12 D 1 L121 L124 R125 G128 W131 H132 E141 H142 S145 R149 G174 E175 R176 H177 E178 I179 G180 L183 V220 L221 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L41 L44 R45 G48 W51 H52 E61 H62 S65 R69 G94 E95 R96 H97 E98 I99 G100 L103 V140 L141 S142 V144 L145 G167 G168 Q169 M184 D186 L187 Q746J7 EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEAL 5c8d A 2.80 BS01 B12 A 1 E117 L121 L124 G128 W131 E141 H142 S145 G174 E175 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 D266 L267 E61 L65 L68 G72 W75 E85 H86 S89 G118 E119 R120 H121 E122 I123 G124 L127 V164 S166 V168 L169 G191 G192 Q193 M208 D210 L211 Q746J7 EDVEALKTIKRWLEEIRRYLAVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 5c8d B 2.80 BS01 B12 B 1 L121 L124 R125 G128 W131 H132 E141 H142 S145 R149 G174 E175 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L66 L69 R70 G73 W76 H77 E86 H87 S90 R94 G119 E120 R121 H122 E123 I124 G125 L128 V165 S167 V169 L170 G192 G193 Q194 M209 D211 L212 Q746J7 VEALKTIKRWPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8d C 2.80 BS01 B12 C 1 E117 L121 L124 R125 G128 E129 W131 H132 E141 H142 S145 G174 E175 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 D266 L267 E65 L69 L72 R73 G76 E77 W79 H80 E89 H90 S93 G122 E123 R124 H125 E126 I127 G128 L131 V168 S170 V172 L173 G195 G196 Q197 M212 D214 L215 Q746J7 LKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW 5c8d D 2.80 BS01 B12 D 1 L121 L124 R125 G128 W131 H132 E141 H142 S145 G174 E175 R176 H177 E178 I179 G180 V220 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L118 L121 R122 G125 W128 H129 E138 H139 S142 G171 E172 R173 H174 E175 I176 G177 V217 S219 V221 L222 G244 G245 Q246 M261 D263 L264 Q746J7 SGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8d E 2.80 BS01 B12 E 1 L121 L124 R125 G128 W131 E141 H142 S145 G174 E175 R176 H177 E178 I179 G180 V220 S222 V224 L225 G247 G248 M264 D266 L267 L118 L121 R122 G125 W128 E138 H139 S142 G171 E172 R173 H174 E175 I176 G177 V217 S219 V221 L222 G244 G245 M261 D263 L264 Q746J7 SGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGPEKE 5c8d F 2.80 BS01 B12 F 1 L121 L124 R125 G128 W131 H132 E141 H142 S145 R149 G174 E175 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L270 L115 L118 R119 G122 W125 H126 E135 H136 S139 R143 G168 E169 R170 H171 E172 I173 G174 L177 V214 S216 V218 L219 G241 G242 Q243 M258 D260 L261 L264 Q746J7 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8d G 2.80 BS01 B12 G 1 L121 L124 R125 G128 W131 H132 E141 H142 S145 G174 E175 R176 H177 E178 I179 G180 V220 L221 S222 V224 L225 G247 G248 Q249 M264 L267 L108 L111 R112 G115 W118 H119 E128 H129 S132 G161 E162 R163 H164 E165 I166 G167 V207 L208 S209 V211 L212 G234 G235 Q236 M251 L254 Q746J7 SGVYTIAEVEAMTGLSAEVLRQWERRYGFPKYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL 5c8d H 2.80 BS01 B12 H 1 L121 L124 R125 G128 W131 H132 E141 H142 S145 G174 E175 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L270 L121 L124 R125 G128 W131 H132 E141 H142 S145 G174 E175 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 D266 L267 L270 Q746J7 LVPRGSHMTSVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 5c8e A 3.89 BS01 NUC I 1 G40 H42 G36 H38 Q746J7 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 5c8e A 3.89 BS02 NUC J 1 A10 R24 R37 G41 H42 R43 A6 R20 R33 G37 H38 R39 Q746J7 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 5c8e A 3.89 BS03 B12 A 1 L121 L124 G128 H132 E141 H142 S145 G174 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 L267 L117 L120 G124 H128 E137 H138 S141 G170 R172 H173 E174 I175 G176 L179 V216 S218 V220 L221 G243 G244 Q245 M260 L263 Q746J7 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 5c8e B 3.89 BS01 NUC I 1 V22 Q25 W26 R29 Y30 T65 P66 K67 V18 Q21 W22 R25 Y26 T61 P62 K63 Q746J7 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGP 5c8e B 3.89 BS02 NUC J 1 Q25 G41 R43 Q21 G37 R39 Q746J7 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGP 5c8e B 3.89 BS03 B12 B 1 L121 L124 R125 G128 H132 E141 H142 S145 G174 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 L267 L117 L120 R121 G124 H128 E137 H138 S141 G170 R172 H173 E174 I175 G176 L179 V216 S218 V220 L221 G243 G244 Q245 M260 L263 Q746J7 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGP 5c8e C 3.89 BS01 NUC I 1 V22 Q25 W26 R29 Y30 G40 H42 P66 K67 V23 Q26 W27 R30 Y31 G41 H43 P67 K68 Q746J7 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5c8e C 3.89 BS02 NUC J 1 I9 A10 R24 R28 R37 G41 H42 R43 I10 A11 R25 R29 R38 G42 H43 R44 Q746J7 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5c8e C 3.89 BS03 B12 C 1 L121 L124 R125 G128 H132 E141 H142 S145 G174 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 L267 L122 L125 R126 G129 H133 E142 H143 S146 G175 R177 H178 E179 I180 G181 L184 V221 S223 V225 L226 G248 G249 Q250 M265 L268 Q746J7 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5c8e D 3.89 BS01 B12 D 1 L121 L124 R125 G128 H132 E141 H142 S145 G174 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 L267 L46 L49 R50 G53 H57 E66 H67 S70 G99 R101 H102 E103 I104 G105 L108 V145 S147 V149 L150 G172 G173 Q174 M189 L192 Q746J7 QEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGP 5c8e E 3.89 BS01 NUC K 1 Q25 T38 G40 H42 Q20 T33 G35 H37 Q746J7 VYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5c8e E 3.89 BS02 NUC L 1 A10 R24 R37 G41 H42 R43 A5 R19 R32 G36 H37 R38 Q746J7 VYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5c8e E 3.89 BS03 B12 E 1 L124 R125 G128 H132 E141 H142 S145 G174 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 L267 L119 R120 G123 H127 E136 H137 S140 G169 R171 H172 E173 I174 G175 L178 V215 S217 V219 L220 G242 G243 Q244 M259 L262 Q746J7 VYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5c8e F 3.89 BS01 NUC K 1 Q25 R29 Y30 P66 K67 Q20 R24 Y25 P57 K58 Q746J7 VYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRG 5c8e F 3.89 BS02 B12 F 1 L121 L124 R125 G128 H132 E141 H142 S145 G174 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 L267 L112 L115 R116 G119 H123 E132 H133 S136 G165 R167 H168 E169 I170 G171 L174 V211 S213 V215 L216 G238 G239 Q240 M255 L258 Q746J7 VYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRG 5c8e G 3.89 BS01 NUC K 1 V22 Q25 W26 R29 Y30 G40 H42 P66 K67 V23 Q26 W27 R30 Y31 G41 H43 P67 K68 Q746J7 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRG 5c8e G 3.89 BS02 NUC L 1 I9 A10 R24 R37 G41 H42 R43 I10 A11 R25 R38 G42 H43 R44 Q746J7 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRG 5c8e G 3.89 BS03 B12 G 1 L121 L124 R125 G128 H132 E141 H142 S145 G174 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 L267 L122 L125 R126 G129 H133 E142 H143 S146 G175 R177 H178 E179 I180 G181 L184 V221 S223 V225 L226 G248 G249 Q250 M265 L268 Q746J7 HMTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRG 5c8e H 3.89 BS01 B12 H 1 L121 L124 R125 G128 H132 E141 H142 S145 G174 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 L45 L48 R49 G52 H56 E65 H66 S69 G98 R100 H101 E102 I103 G104 L107 V144 S146 V148 L149 G171 G172 Q173 M188 Q746J7 EVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP 5c8f A 2.65 BS01 B12 A 1 R125 G128 E129 W131 H132 R176 H177 E178 I179 G180 L183 V220 S222 V224 L225 G247 G248 Q249 M264 D266 L267 R121 G124 E125 W127 H128 R172 H173 E174 I175 G176 L179 V216 S218 V220 L221 G243 G244 Q245 M260 D262 L263 Q746J7 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPR 5c91 A 2.44 BS01 4YU A 1 E554 Y604 Y605 L607 N621 N623 S624 C627 N628 Y634 E36 Y86 Y87 L89 N103 N105 S106 C109 N110 Y116 6.3.2.- P46934 SRDYKRKYEFFRRKLKKQNDIPNKFEMKLRRATVLEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPTELDLRFIIDEELFGQTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPEKLPRAHTCFNRLDLPPYESFEELWDKLQMAIENT 5cfb A 3.04 BS01 SY9 A 1 E157 F159 Y202 T204 F207 E149 F151 Y194 T196 F199 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRAGTKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cfb A 3.04 BS02 SY9 E 1 F44 F63 R65 L117 L127 F36 F55 R57 L109 L119 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRAGTKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cfb B 3.04 BS01 SY9 A 1 F63 R65 L117 R119 L127 F55 R57 L109 R111 L119 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRAGTKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cfb B 3.04 BS02 SY9 B 1 F159 Y202 F207 F151 Y194 F199 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRAGTKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cfb C 3.04 BS01 SY9 B 1 F44 F63 R65 L117 R119 F36 F55 R57 L109 R111 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRAGTKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cfb C 3.04 BS02 SY9 C 1 F159 Y202 T204 F207 F151 Y194 T196 F199 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRAGTKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cfb D 3.04 BS01 SY9 C 1 F44 F63 R65 L117 F36 F55 R57 L109 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cfb D 3.04 BS02 SY9 D 1 E157 F159 Y202 T204 F207 E149 F151 Y194 T196 F199 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cfb E 3.04 BS01 SY9 D 1 F44 F63 R65 L117 R119 L127 F36 F55 R57 L109 R111 L119 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRAGTKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cfb E 3.04 BS02 SY9 E 1 F159 Y202 T204 F207 F151 Y194 T196 F199 O75311 SPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRAGTKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKI 5cku A 2.10 BS01 FAD A 1 G46 G48 P49 A50 L82 E83 R84 Q85 W90 H91 M94 M101 Q102 I103 E166 E167 V168 A209 I210 G211 Y407 R409 S466 L467 L468 G23 G25 P26 A27 L55 E56 R57 Q58 W63 H64 M67 M74 Q75 I76 E139 E140 V141 A182 I183 G184 Y370 R372 S429 L430 L431 1.14.13.196 E9QYP0 26375201 LSLDPPRLRSTPQDELHDLLCVGFGPASLAIAIALHDALDPRLNKSAAQPKICFLERQKQFAWHSGMLVPGSKMQISFIKDLATLRDPRSSFTFLNYLHQKGRLIHFTNLSTFLPARLEFEDYMRWCAQQFSDVVAYGEEVVEVIPGKSDPSSSVVDFFTVRSRNVETGEISARRTRKVVIAIGGTAKMPSGLPQDPRIIHSSKYCTTLPALLKDKSKPYNIAVLGSGQSAAEIFHDLQKRYPNSRTTLIMRDSAMRPSDDSPFVNEIFNPERVDKFYSQSAAERQRSLLADKATAYSVVRLELIEEIYNDMYLQRVKNPDETQWQHRILPERKITRVEHHGPQSRMRIHLKSSKPETLEVDALMVATGYNRNAHERLLSKVQHLRPTGQDQWKPHRDYRVEMDPSKVSSEAGIWLQGCNERTHGLSDSLLSVLAVRGGEMVQSIFGEQLE 5cku A 2.10 BS02 NAP A 1 P217 S254 G255 Q256 S257 R279 Y324 S325 A404 T405 G406 P190 S227 G228 Q229 S230 R252 Y297 S298 A367 T368 G369 1.14.13.196 E9QYP0 26375201 LSLDPPRLRSTPQDELHDLLCVGFGPASLAIAIALHDALDPRLNKSAAQPKICFLERQKQFAWHSGMLVPGSKMQISFIKDLATLRDPRSSFTFLNYLHQKGRLIHFTNLSTFLPARLEFEDYMRWCAQQFSDVVAYGEEVVEVIPGKSDPSSSVVDFFTVRSRNVETGEISARRTRKVVIAIGGTAKMPSGLPQDPRIIHSSKYCTTLPALLKDKSKPYNIAVLGSGQSAAEIFHDLQKRYPNSRTTLIMRDSAMRPSDDSPFVNEIFNPERVDKFYSQSAAERQRSLLADKATAYSVVRLELIEEIYNDMYLQRVKNPDETQWQHRILPERKITRVEHHGPQSRMRIHLKSSKPETLEVDALMVATGYNRNAHERLLSKVQHLRPTGQDQWKPHRDYRVEMDPSKVSSEAGIWLQGCNERTHGLSDSLLSVLAVRGGEMVQSIFGEQLE 5cku A 2.10 BS03 ORN A 1 I103 K107 N293 F296 L467 S469 I76 K80 N266 F269 L430 S432 1.14.13.196 E9QYP0 26375201 LSLDPPRLRSTPQDELHDLLCVGFGPASLAIAIALHDALDPRLNKSAAQPKICFLERQKQFAWHSGMLVPGSKMQISFIKDLATLRDPRSSFTFLNYLHQKGRLIHFTNLSTFLPARLEFEDYMRWCAQQFSDVVAYGEEVVEVIPGKSDPSSSVVDFFTVRSRNVETGEISARRTRKVVIAIGGTAKMPSGLPQDPRIIHSSKYCTTLPALLKDKSKPYNIAVLGSGQSAAEIFHDLQKRYPNSRTTLIMRDSAMRPSDDSPFVNEIFNPERVDKFYSQSAAERQRSLLADKATAYSVVRLELIEEIYNDMYLQRVKNPDETQWQHRILPERKITRVEHHGPQSRMRIHLKSSKPETLEVDALMVATGYNRNAHERLLSKVQHLRPTGQDQWKPHRDYRVEMDPSKVSSEAGIWLQGCNERTHGLSDSLLSVLAVRGGEMVQSIFGEQLE 5clm A 2.61 BS01 52K A 1 G11 Q12 G13 L30 D32 Y71 F108 I110 I118 D228 S229 G230 T232 A335 G13 Q14 G15 L32 D34 Y73 F110 I112 I120 D222 S223 G224 T226 A326 3.4.23.46 P56817 26378740 FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVADDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 5czh A 2.80 BS01 III B 1 D837 R841 G873 G874 K875 V876 P877 K879 W880 P919 A920 D142 R146 G178 G179 K180 V181 P182 K184 W185 P224 A225 2.7.10.1 P00533 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPDEEDMDDVVDADEYLI 5czi A 2.60 BS01 III B 1 D837 R841 K875 V876 P877 K879 R889 A920 D142 R146 K180 V181 P182 K184 R194 A225 2.7.10.1 P00533 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPDEDMDDVVDADEYLI 5d1r A 2.00 BS01 MG A 1 N109 P110 A111 R112 N97 P98 A99 R100 P9WMC8 26362239 AREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEHHHHHH 5d1r A 2.00 BS02 56S A 1 A132 T136 V139 F142 F143 C189 F190 W193 A120 T124 V127 F130 F131 C177 F178 W181 P9WMC8 26362239 AREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEHHHHHH 5d1r B 2.00 BS01 56S A 1 Q207 Y208 G209 A210 M212 Q194 Y195 G196 A197 M199 P9WMC8 26362239 REQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEHHHHHH 5d1r B 2.00 BS02 MG B 1 L30 N109 P110 A111 R112 L17 N96 P97 A98 R99 P9WMC8 26362239 REQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEHHHHHH 5d3g A 2.30 BS01 NUC E 1 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 Y115 Q151 G152 K154 P157 Y183 M184 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 K353 A355 R358 G359 A360 H361 R448 T473 Q475 K476 Y501 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 Y115 Q151 G152 K154 P157 Y183 M184 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 K353 A355 R358 G359 A360 H361 R448 T473 Q475 K476 Y501 2.7.7.49 P03366 26296781 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5d3g B 2.30 BS01 NUC E 1 K22 K395 K19 K382 2.7.7.49 P03366 26296781 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5d3g C 2.30 BS01 NUC F 1 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 Y115 Q151 G152 K154 P157 Y183 M184 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 T286 K353 A355 G359 A360 H361 K374 R448 T473 Q475 K476 Y501 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 Y115 Q151 G152 K154 P157 Y183 M184 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 T286 K353 A355 G359 A360 H361 K374 R448 T473 Q475 K476 Y501 2.7.7.49 P03366 26296781 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5d3g D 2.30 BS01 NUC F 1 K22 K395 K17 K378 2.7.7.49 P03366 26296781 ETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWY 5dao A 1.75 BS01 CU A 1 H111 H398 H400 H450 H111 H398 H400 H450 1.10.3.2 AIGPVADLKIVNANIQPDGFTRPAVLAGGTFPGPLIKGNKGDNFQLNVIDELENEDMLKSTSIHWHGFFQHGTNWADGPAFVNQCPITTGHSFLYNFHVPDQAGTFWYHSHLSTQYCDGLRGPMVVYDPHDPLKQLYDVDDESTVMTLADWYHTLARQEPPGPVTPDSTLINGLGRAPGQTTPSELAVLTVKRGTRYRIRLINISCEPNYHYSIDNHDLTVIEADGVSTQSLTVSSLTIFAGQRYSFILNANQPVGNYWIRAQPNDAADVTFNGGINSAILRYEGAPVAEPNTTAGPDNTPLLEVNIRPFVFTPVPGQPHAGGADFVKNLLFSFNGTNFQVDNVSFVPPTVPILLQILSGAHTAQDLMPAGSIIPLPKNAVIEFSMPGGVVGGGHPIHLHGHNFWVIRSANSSVYNYNDPVIRDVVNIGTTGDNVTIRFETNNPGPWFLHCHIDWHLDLGFAVVMAEDIPDAAAANPVPAAWNELCPLYDALTPGNQ 5dao A 1.75 BS02 CU A 2 H66 H109 H452 H66 H109 H452 1.10.3.2 AIGPVADLKIVNANIQPDGFTRPAVLAGGTFPGPLIKGNKGDNFQLNVIDELENEDMLKSTSIHWHGFFQHGTNWADGPAFVNQCPITTGHSFLYNFHVPDQAGTFWYHSHLSTQYCDGLRGPMVVYDPHDPLKQLYDVDDESTVMTLADWYHTLARQEPPGPVTPDSTLINGLGRAPGQTTPSELAVLTVKRGTRYRIRLINISCEPNYHYSIDNHDLTVIEADGVSTQSLTVSSLTIFAGQRYSFILNANQPVGNYWIRAQPNDAADVTFNGGINSAILRYEGAPVAEPNTTAGPDNTPLLEVNIRPFVFTPVPGQPHAGGADFVKNLLFSFNGTNFQVDNVSFVPPTVPILLQILSGAHTAQDLMPAGSIIPLPKNAVIEFSMPGGVVGGGHPIHLHGHNFWVIRSANSSVYNYNDPVIRDVVNIGTTGDNVTIRFETNNPGPWFLHCHIDWHLDLGFAVVMAEDIPDAAAANPVPAAWNELCPLYDALTPGNQ 5dao A 1.75 BS03 CU A 3 H64 H398 H400 H64 H398 H400 1.10.3.2 AIGPVADLKIVNANIQPDGFTRPAVLAGGTFPGPLIKGNKGDNFQLNVIDELENEDMLKSTSIHWHGFFQHGTNWADGPAFVNQCPITTGHSFLYNFHVPDQAGTFWYHSHLSTQYCDGLRGPMVVYDPHDPLKQLYDVDDESTVMTLADWYHTLARQEPPGPVTPDSTLINGLGRAPGQTTPSELAVLTVKRGTRYRIRLINISCEPNYHYSIDNHDLTVIEADGVSTQSLTVSSLTIFAGQRYSFILNANQPVGNYWIRAQPNDAADVTFNGGINSAILRYEGAPVAEPNTTAGPDNTPLLEVNIRPFVFTPVPGQPHAGGADFVKNLLFSFNGTNFQVDNVSFVPPTVPILLQILSGAHTAQDLMPAGSIIPLPKNAVIEFSMPGGVVGGGHPIHLHGHNFWVIRSANSSVYNYNDPVIRDVVNIGTTGDNVTIRFETNNPGPWFLHCHIDWHLDLGFAVVMAEDIPDAAAANPVPAAWNELCPLYDALTPGNQ 5dao A 1.75 BS04 CU A 4 H395 C451 H456 H395 C451 H456 1.10.3.2 AIGPVADLKIVNANIQPDGFTRPAVLAGGTFPGPLIKGNKGDNFQLNVIDELENEDMLKSTSIHWHGFFQHGTNWADGPAFVNQCPITTGHSFLYNFHVPDQAGTFWYHSHLSTQYCDGLRGPMVVYDPHDPLKQLYDVDDESTVMTLADWYHTLARQEPPGPVTPDSTLINGLGRAPGQTTPSELAVLTVKRGTRYRIRLINISCEPNYHYSIDNHDLTVIEADGVSTQSLTVSSLTIFAGQRYSFILNANQPVGNYWIRAQPNDAADVTFNGGINSAILRYEGAPVAEPNTTAGPDNTPLLEVNIRPFVFTPVPGQPHAGGADFVKNLLFSFNGTNFQVDNVSFVPPTVPILLQILSGAHTAQDLMPAGSIIPLPKNAVIEFSMPGGVVGGGHPIHLHGHNFWVIRSANSSVYNYNDPVIRDVVNIGTTGDNVTIRFETNNPGPWFLHCHIDWHLDLGFAVVMAEDIPDAAAANPVPAAWNELCPLYDALTPGNQ 5dao A 1.75 BS05 ZN A 1 H362 D366 H362 D366 1.10.3.2 AIGPVADLKIVNANIQPDGFTRPAVLAGGTFPGPLIKGNKGDNFQLNVIDELENEDMLKSTSIHWHGFFQHGTNWADGPAFVNQCPITTGHSFLYNFHVPDQAGTFWYHSHLSTQYCDGLRGPMVVYDPHDPLKQLYDVDDESTVMTLADWYHTLARQEPPGPVTPDSTLINGLGRAPGQTTPSELAVLTVKRGTRYRIRLINISCEPNYHYSIDNHDLTVIEADGVSTQSLTVSSLTIFAGQRYSFILNANQPVGNYWIRAQPNDAADVTFNGGINSAILRYEGAPVAEPNTTAGPDNTPLLEVNIRPFVFTPVPGQPHAGGADFVKNLLFSFNGTNFQVDNVSFVPPTVPILLQILSGAHTAQDLMPAGSIIPLPKNAVIEFSMPGGVVGGGHPIHLHGHNFWVIRSANSSVYNYNDPVIRDVVNIGTTGDNVTIRFETNNPGPWFLHCHIDWHLDLGFAVVMAEDIPDAAAANPVPAAWNELCPLYDALTPGNQ 5de9 A 1.76 BS01 HEM A 1 R71 V93 G94 H101 R105 F112 L239 G242 A245 N249 L282 H287 R295 Y318 S345 F346 H351 C353 P354 A359 R67 V89 G90 H97 R101 F108 L235 G238 A241 N245 L278 H283 R291 Y314 S341 F342 H347 C349 P350 A355 1.14.21.7 Q9FCA6 22203090 TISQAVPPVRDWPAVDLPGSDFDPVLTELMREGPVTRISLPNGEGWAWLVTRHDDVRLVTNDPRFGREAVMDRQVTRLAPHFRPARGAVGFLDPPDHTRLRRSVAAAFTARGVERVRERSRGMLDELVDAMLRAGPPADLTEAVLSPFPIAVICELMGVPATDRHSMHTWTQLILSSSHGAEVSERAKNEMNAYFSDLIGLRSDSAGEDVTSLLGAAVGRDEITLSEAVGLAVLLQIGGEAVTNNSGQMFHLLLSRPELAERLRSEPEIRPRAIDELLRWIPHRNAVGLSRIALEDVEIKGVRIRAGDAVYVSYLAANRDPEVFPDPDRIDFERSPNPHVSFGFGPHYCPGGMLARLESELLVDAVLDRVPGLKLAVAPEDVPFKKGALIRGPEALPVTWHH 5de9 B 1.76 BS01 HEM B 1 R71 V93 G94 H101 R105 F112 L239 G242 G243 A245 V246 N249 H287 R295 Y318 S345 F346 H351 C353 P354 A359 R67 V89 G90 H97 R101 F108 L235 G238 G239 A241 V242 N245 H283 R291 Y314 S341 F342 H347 C349 P350 A355 1.14.21.7 Q9FCA6 22203090 TISQAVPPVRDWPAVDLPGSDFDPVLTELMREGPVTRISLPNGEGWAWLVTRHDDVRLVTNDPRFGREAVMDRQVTRLAPHFRPARGAVGFLDPPDHTRLRRSVAAAFTARGVERVRERSRGMLDELVDAMLRAGPPADLTEAVLSPFPIAVICELMGVPATDRHSMHTWTQLILSSSHGAEVSERAKNEMNAYFSDLIGLRSDSAGEDVTSLLGAAVGRDEITLSEAVGLAVLLQIGGEAVTNNSGQMFHLLLSRPELAERLRSEPEIRPRAIDELLRWIPHRNAVGLSRIALEDVEIKGVRIRAGDAVYVSYLAANRDPEVFPDPDRIDFERSPNPHVSFGFGPHYCPGGMLARLESELLVDAVLDRVPGLKLAVAPEDVPFKKGALIRGPEALPVTWHH 5dgn F 2.08 BS01 59Y F 1 Y10 K57 Y58 N59 R60 T63 S205 F206 F239 L344 K347 I348 Y3 K50 Y51 N52 R53 T56 S198 F199 F232 L337 K340 I341 2.5.1.10,2.5.1.1 P14324 26381451 DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 5diq F 2.10 BS01 5B9 F 1 Y10 K57 N59 R60 T63 S205 F206 F239 K257 L344 K347 I348 Y3 K50 N52 R53 T56 S198 F199 F232 K250 L337 K340 I341 2.5.1.10,2.5.1.1 P14324 26381451 DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRR 5djp F 2.40 BS01 5BJ F 1 Y10 K57 N59 R60 T63 S205 F206 F239 L344 K347 I348 Y3 K50 N52 R53 T56 S198 F199 F232 L337 K340 I341 2.5.1.10,2.5.1.1 P14324 26381451 DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 5djr F 2.40 BS01 5BK F 1 Y10 K57 N59 R60 T63 S205 F206 F239 L344 Y2 K49 N51 R52 T55 S197 F198 F231 L336 2.5.1.10,2.5.1.1 P14324 26381451 VYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 5dkv A 1.68 BS01 T6T A 1 D44 F46 Y47 D121 T179 R183 N233 L234 D259 Q279 D18 F20 Y21 D95 T153 R157 N207 L208 D233 Q253 B9K0T2 SMENKKFRIALIPGLTTDAFYITMHKGAEAAAAAIGAQIIFQGAPDFNPVTQVPVLDAVIAKKPDAILIAPTDTTQLVQPLKKAADAGIPMITVDTFIGTGDYQTGAGDGDFPLSYIASDNVLGGEIAARSLALAIGDKGKVYVSNVKPGVSTTDQREQGFKSEMAKHPGITVLETQFNDNDANKAASQLQAVYARNPDLAGVFGANLFSGLGSANGVQQAGQSGTIKVVAFDAPGSVVDNLKSGLIDFAIAQHPAEIGYYGVISAYAHLTGQSIPTKIGTGFTVINKSNVTDPAVARFIYAE 5dkv B 1.68 BS01 T6T B 1 D44 F46 Y47 F73 D121 T122 T179 R183 N233 L234 D259 Q279 D15 F17 Y18 F44 D92 T93 T150 R154 N204 L205 D230 Q250 B9K0T2 NKKFRIALIPGLTTDAFYITMHKGAEAAAAAIGAQIIFQGAPDFNPVTQVPVLDAVIAKKPDAILIAPTDTTQLVQPLKKAADAGIPMITVDTFIGTGDYQTGAGDGDFPLSYIASDNVLGGEIAARSLALAIGDKGKVYVSNVKPGVSTTDQREQGFKSEMAKHPGITVLETQFNDNDANKAASQLQAVYARNPDLAGVFGANLFSGLGSANGVQQAGQSGTIKVVAFDAPGSVVDNLKSGLIDFAIAQHPAEIGYYGVISAYAHLTGQSIPTKIGTGFTVINKSNVTDPAVARFIYAE 5dkv C 1.68 BS01 T6T C 1 D44 F46 Y47 F73 D121 T122 T179 R183 N233 L234 D259 Q279 D13 F15 Y16 F42 D90 T91 T148 R152 N202 L203 D228 Q248 B9K0T2 KFRIALIPGLTTDAFYITMHKGAEAAAAAIGAQIIFQGAPDFNPVTQVPVLDAVIAKKPDAILIAPTDTTQLVQPLKKAADAGIPMITVDTFIGTGDYQTGAGDGDFPLSYIASDNVLGGEIAARSLALAIGDKGKVYVSNVKPGVSTTDQREQGFKSEMAKHPGITVLETQFNDNDANKAASQLQAVYARNPDLAGVFGANLFSGLGSANGVQQAGQSGTIKVVAFDAPGSVVDNLKSGLIDFAIAQHPAEIGYYGVISAYAHLTGQSIPTKIGTGFTVINKSNVTDPAVARFIYAE 5dkv D 1.68 BS01 T6T D 1 D44 F46 Y47 F73 D121 T122 T179 R183 N233 L234 D259 Q279 D13 F15 Y16 F42 D90 T91 T148 R152 N202 L203 D228 Q248 B9K0T2 KFRIALIPGLTTDAFYITMHKGAEAAAAAIGAQIIFQGAPDFNPVTQVPVLDAVIAKKPDAILIAPTDTTQLVQPLKKAADAGIPMITVDTFIGTGDYQTGAGDGDFPLSYIASDNVLGGEIAARSLALAIGDKGKVYVSNVKPGVSTTDQREQGFKSEMAKHPGITVLETQFNDNDANKAASQLQAVYARNPDLAGVFGANLFSGLGSANGVQQAGQSGTIKVVAFDAPGSVVDNLKSGLIDFAIAQHPAEIGYYGVISAYAHLTGQSIPTKIGTGFTVINKSNVTDPAVARFIYAE 5dld A 1.45 BS01 UDP A 1 R11 P12 I15 H214 R215 P245 Q272 Y274 F277 S291 G292 G293 I294 E297 R12 P13 I16 H215 R216 P246 Q273 Y275 F278 S292 G293 G294 I295 E298 5.1.3.14 A4JLG9 HMKKILLVFGTRPEAIKMAPLVRALKARADVDAKVCVTAQHRQMLDQVLSLFDIEPDYDLDLMRQGQTLSDVTTGILHAIGAVFDDLRPDIVLVHGDTTTTLAVSLAAFYRYLPIGHVEAGLRSGDIWSPWPEELNRRVTDAVSSWHFAPTGQARDNLLSEGVPVGSVVMTGNTVIDALHDVKHMLERDDALSREVAARFPFLDPTARMVLITGHRRESFGEPFRNFCEALRTLAHRYRDAQFVYPLHLNPNVREPALALLGGEANIYLIEPQEYLAFVYLMSRSHFIITDSGGIQEEGPALGKPVLVTRDTTERPEAIRAGTARLVGTDPELIVREASRLFDSASAYDEMARASNPYGDGHASERIVHALMHAELPLN 5dld A 1.45 BS02 UD1 A 1 P12 Q39 H40 R41 Q42 M43 M62 R63 Q64 G65 Q66 L68 T97 T98 P131 E132 H214 R215 R216 H247 L248 N249 P250 P13 Q40 H41 R42 Q43 M44 M63 R64 Q65 G66 Q67 L69 T98 T99 P132 E133 H215 R216 R217 H248 L249 N250 P251 5.1.3.14 A4JLG9 HMKKILLVFGTRPEAIKMAPLVRALKARADVDAKVCVTAQHRQMLDQVLSLFDIEPDYDLDLMRQGQTLSDVTTGILHAIGAVFDDLRPDIVLVHGDTTTTLAVSLAAFYRYLPIGHVEAGLRSGDIWSPWPEELNRRVTDAVSSWHFAPTGQARDNLLSEGVPVGSVVMTGNTVIDALHDVKHMLERDDALSREVAARFPFLDPTARMVLITGHRRESFGEPFRNFCEALRTLAHRYRDAQFVYPLHLNPNVREPALALLGGEANIYLIEPQEYLAFVYLMSRSHFIITDSGGIQEEGPALGKPVLVTRDTTERPEAIRAGTARLVGTDPELIVREASRLFDSASAYDEMARASNPYGDGHASERIVHALMHAELPLN 5dly A 1.50 BS01 5D7 A 1 F21 Y33 D34 T38 L132 C133 G135 L136 D161 L162 Y182 L183 Q186 S190 M255 P256 F20 Y32 D33 T37 L131 C132 G134 L135 D160 L161 Y181 L182 Q185 S189 M254 P255 A7Z2A9 EIETIVRESEANRIQAQTWFSHPEKSKVSFRYDERETSSIRSISIETFLSFYSSKFNREPYSVLDIGCGQGQVIQYLNSRFQKIELTGIDSSAQAISSAKKLGINASFICSNAENIMQYVSKKQDIIFIHLCFGLFKNPIAIVNTLIHLLSDQSCIYIVDLDRNSLGEGLNTAQSREEEAYLKDQYRASLTMEEFKQLLHVVTKEQHGVSFHVGNSFIGGFDETSSQFFSLMRNRNLQDALRTSVGEQLKQSQMPALLHGWIIKNK 5dly A 1.50 BS02 SAH A 1 Q18 F21 G68 D91 S92 S93 N113 A114 H131 C133 L136 F137 Q17 F20 G67 D90 S91 S92 N112 A113 H130 C132 L135 F136 A7Z2A9 EIETIVRESEANRIQAQTWFSHPEKSKVSFRYDERETSSIRSISIETFLSFYSSKFNREPYSVLDIGCGQGQVIQYLNSRFQKIELTGIDSSAQAISSAKKLGINASFICSNAENIMQYVSKKQDIIFIHLCFGLFKNPIAIVNTLIHLLSDQSCIYIVDLDRNSLGEGLNTAQSREEEAYLKDQYRASLTMEEFKQLLHVVTKEQHGVSFHVGNSFIGGFDETSSQFFSLMRNRNLQDALRTSVGEQLKQSQMPALLHGWIIKNK 5dn1 A 1.95 BS01 AMZ A 1 L20 G23 L54 F58 S81 G83 R85 G104 T105 D130 G140 W141 L20 G23 L54 F58 S81 G83 R85 G104 T105 D130 G140 W141 5.3.1.16,5.3.1.24 P16250 MSKLELLPAVDVRDGQAVRLVHGESGTETSYGSPLEAALAWQRSGAEWLHLVDLDAAFGTGDNRALIAEVAQAMDIKVELSGGIRDDDTLAAALATGCTRVNLGTAALETPEWVAKVIAEHGDKIAVGLDVRGTTLRGRGWTRDGGDLYETLDRLNKEGCARYVVTDIAKDGTLQGPNLELLKNVCAATDRPVVASGGVSSLDDLRAIAGLVPAGVEGAIVGKALYAKAFTLEEALEATS 5do8 B 1.80 BS01 BGC B 1 D61 Y64 H104 F142 F161 Q165 R195 D197 E254 H327 D328 R413 D59 Y62 H102 F140 F159 Q163 R193 D195 E252 H325 D326 R411 Q8YAE6 EKDWWKKSVVYQIYPKSFNDSNGDGVGDIQGIIEKLDYLKELGVDVIWLSPVYDSPQDDNGYDIRDYQKIYEEYGDMATFDQLLQGLHDRDMKLVMDLVVNHTSDEHKWFEESRKSKDNPYRDYYFWREENEINNWGSIFSGPAWELDEKTGEYYLHLFSKKQPDLNWENPKLRQDVYNMMKFWLDKGIDGFRMDVINFISKNTDFPDGPVPDGQIYGDAGNDFCNGPRIHEFLQEMNQEVTSKYDVMTVGEMPGASTTDAQIYTNPANNEVDMIFTFEHMNLDSDSDNKWDLKPIYLPDLKENMSEWQVALQENGWNSLYWNNHDQPRIVSRFGNDNRFRVRSAKMLATCLHMMKGTPYIYQGEEIGMTNVHFETLDDYRDIETLNMYKERKEQGHSHESIMQSIYTKGRDNARTPYQWDNSENAGFTTGTPWLKVNPRYTEINNEEALKNPDSIFYYYQNLIKLRKTTEIITTGNYRLLLPKDEAIFAYERYTENEKLVVLCNFTEEEQVISDETILNEIQKGSVLVNNVPNIIEGTLRPYEAIVYQIKGA 5do8 A 1.80 BS01 BGC A 1 D61 Y64 H104 F142 F161 Q165 R195 D197 E254 H327 D328 R413 D59 Y62 H102 F140 F159 Q163 R193 D195 E252 H325 D326 R411 Q8YAE6 EKDWWKKSVVYQIYPKSFNDSNGDGVGDIQGIIEKLDYLKELGVDVIWLSPVYDSPQDDNGYDIRDYQKIYEEYGDMATFDQLLQGLHDRDMKLVMDLVVNHTSDEHKWFEESRKSKDNPYRDYYFWREENEINNWGSIFSGPAWELDEKTGEYYLHLFSKKQPDLNWENPKLRQDVYNMMKFWLDKGIDGFRMDVINFISKNTDFPDGPVPDGQIYGDAGNDFCNGPRIHEFLQEMNQEVTSKYDVMTVGEMPGASTTDAQIYTNPANNEVDMIFTFEHMNLDSDSDNKWDLKPIYLPDLKENMSEWQVALQENGWNSLYWNNHDQPRIVSRFGNDNRFRVRSAKMLATCLHMMKGTPYIYQGEEIGMTNVHFETLDDYRDIETLNMYKERKEQGHSHESIMQSIYTKGRDNARTPYQWDNSENAGFTTGTPWLKVNPRYTEINNEEALKNPDSIFYYYQNLIKLRKTTEIITTGNYRLLLPKDEAIFAYERYTENEKLVVLCNFTEEEQVISDETILNEIQKGSVLVNNVPNIIEGTLRPYEAIVYQIKG 5do8 C 1.80 BS01 BGC C 1 D61 Y64 H104 F142 F161 Q165 R195 D197 E254 H327 D328 R413 D58 Y61 H101 F139 F158 Q162 R192 D194 E251 H324 D325 R410 Q8YAE6 KDWWKKSVVYQIYPKSFNDSNGDGVGDIQGIIEKLDYLKELGVDVIWLSPVYDSPQDDNGYDIRDYQKIYEEYGDMATFDQLLQGLHDRDMKLVMDLVVNHTSDEHKWFEESRKSKDNPYRDYYFWREENEINNWGSIFSGPAWELDEKTGEYYLHLFSKKQPDLNWENPKLRQDVYNMMKFWLDKGIDGFRMDVINFISKNTDFPDGPVPDGQIYGDAGNDFCNGPRIHEFLQEMNQEVTSKYDVMTVGEMPGASTTDAQIYTNPANNEVDMIFTFEHMNLDSDSDNKWDLKPIYLPDLKENMSEWQVALQENGWNSLYWNNHDQPRIVSRFGNDNRFRVRSAKMLATCLHMMKGTPYIYQGEEIGMTNVHFETLDDYRDIETLNMYKERKEQGHSHESIMQSIYTKGRDNARTPYQWDNSENAGFTTGTPWLKVNPRYTEINNEEALKNPDSIFYYYQNLIKLRKTTEIITTGNYRLLLPKDEAIFAYERYTENEKLVVLCNFTEEEQVISDETILNEIQKGSVLVNNVPNIIEGTLRPYEAIVYQIKG 5dt9 A 2.66 BS01 NAD A 1 N98 V102 G130 A131 G132 Q133 V134 D153 P154 K156 H181 T182 P183 W190 T192 A213 A214 R215 D239 H261 A263 G264 N95 V99 G127 A128 G129 Q130 V131 D150 P151 K153 H178 T179 P180 W187 T189 A210 A211 R212 D236 H258 A260 G261 1.1.1.290 Q9KQ92 IPTMKILIDENMPYAQALFSQLGEVILKPGRTLTADDLIDVDALMIRSVTKVNDALLAKANRLKFVGTATAGMDHVDQALLRERGIFFTAAPGCNKVGVAEYVFSVLMVLAQQQGFSVFDKTVGIIGAGQVGSYLAKCLSGIGMKVLLNDPPKQAQGDEREFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAALKARLQQGDGFTAVLDVFEFEPQVDMELLPLLAFATPHIAGYGLEGKARGTTMIFNSYCEFLGSAHCANPASLLPKAPVPKVYLERAWDEETLRTLTQIIYDVRKDDAQFRREIHQPGAFDLMRKHYWDRREYSAVTLAGGADCHLAPLAKLGFQVEVC 5dul A 2.60 BS01 NDP A 1 G8 T10 G11 S12 I13 A35 G36 R37 N38 A100 I101 V102 A123 N124 K125 D150 G11 T13 G14 S15 I16 A38 G39 R40 N41 A103 I104 V105 A126 N127 K128 D153 1.1.1.267 Q8ZH62 SNAMKQLTILGSTGSIGNSTLSVVRANPELFKVTALVAGRNVREMAQQCLEFSPRYAAMSDEHSAKSLRLLLAEQGSDTEVYSGETAACELAALDDVDQVMAAIVGIAGLPSTLAAIRAGKQVLLANKESLITCGKLFMDEVKRSRAQLLPIDSEHNAIFQSLPERIQRQLGYSSLNENGVSRIILTGSGGPFRVTPISVDSATMMNKGLEYIEARWLFNASAEQIEVVLHPQSVIHSMVRYHDGSILAQMGTPDMRTPIAHAMAYPMRVSSGVAPLDFCKVGALTFTTPDYQRYPCLKLAIDACNAGQAATTALNAANEISVMAFLDSKIRFTDIEVINRTVVEGLLLSEPTSVEEVLVIDRKARDVAAQVIAK 5dul B 2.60 BS01 NDP B 1 G8 T10 G11 S12 I13 A35 G36 R37 N38 S57 A100 I101 V102 A123 N124 K125 M276 G8 T10 G11 S12 I13 A35 G36 R37 N38 S57 A100 I101 V102 A123 N124 K125 M270 1.1.1.267 Q8ZH62 MKQLTILGSTGSIGNSTLSVVRANPELFKVTALVAGRNVREMAQQCLEFSPRYAAMSDEHSAKSLRLLLAEQGSDTEVYSGETAACELAALDDVDQVMAAIVGIAGLPSTLAAIRAGKQVLLANKESLITCGKLFMDEVKRSRAQLLPIDSEHNAIFQSLPERIQRQLGYSSLNENGVSRIILTGSGGPFRETPLSQFSDVTPDQACAGRKISVDSATMMNKGLEYIEARWLFNASAEQIEVVLHPQSVIHSMVRYHDGSILAQMGTPDMRTPIAHAMAYPMRVSSGVAPLDFCKVGALTFTTPDYQRYPCLKLAIDACNAGQAATTALNAANEISVMAFLDSKIRFTDIEVINRTVVEGLLLSEPTSVEEVLVIDRKARDVAAQVIAKL 5dul C 2.60 BS01 NDP C 1 G8 T10 G11 S12 I13 A35 G36 R37 N38 S57 A100 I101 A123 N124 K125 D150 M276 G11 T13 G14 S15 I16 A38 G39 R40 N41 S60 A101 I102 A124 N125 K126 D151 M248 1.1.1.267 Q8ZH62 SNAMKQLTILGSTGSIGNSTLSVVRANPELFKVTALVAGRNVREMAQQCLEFSPRYAAMSDEHSAKSLRLLLAESDTEVYSGETAACELAALDDVDQVMAAIVGIAGLPSTLAAIRAGKQVLLANKESLITCGKLFMDEVKRSRAQLLPIDSEHNAIFQSLPERIQRQLGYSSLNENGVSRIILTGSDVTPVDSATMMNKGLEYIEARWLFNASAEQIEVVLHPQSVIHSMVRYHDGSILAQMGTPDMRTPIAHAMAYPMRVSSGVAPLDFCKVGALTFTTPDYQRYPCLKLAIDACNAGQAATTALNAANEISVMAFLDSKIRFTDIEVINRTVVEGLLLSEPTSVEEVLVIDRKARDVAAQVIAK 5dul D 2.60 BS01 NDP D 1 G8 T10 G11 S12 I13 A35 G36 R37 N38 S57 A100 I101 V102 A105 A123 N124 K125 D150 M276 G8 T10 G11 S12 I13 A35 G36 R37 N38 S57 A100 I101 V102 A105 A123 N124 K125 D150 M268 1.1.1.267 Q8ZH62 MKQLTILGSTGSIGNSTLSVVRANPELFKVTALVAGRNVREMAQQCLEFSPRYAAMSDEHSAKSLRLLLAEQGSDTEVYSGETAACELAALDDVDQVMAAIVGIAGLPSTLAAIRAGKQVLLANKESLITCGKLFMDEVKRSRAQLLPIDSEHNAIFQSLPERIQRQLGYSSLNENGVSRIILTGSGGPFRETPLSQFSDVTPDQACRKISVDSATMMNKGLEYIEARWLFNASAEQIEVVLHPQSVIHSMVRYHDGSILAQMGTPDMRTPIAHAMAYPMRVSSGVAPLDFCKVGALTFTTPDYQRYPCLKLAIDACNAGQAATTALNAANEISVMAFLDSKIRFTDIEVINRTVVEGLLLSEPTSVEEVLVIDRKARDVAAQVIAK 5dvr A 2.40 BS01 5G9 A 1 L57 G60 S61 V65 A78 K80 M112 L126 E129 Y131 L181 I194 D195 L14 G17 S18 V22 A35 K37 M67 L81 E84 Y86 L136 I149 D150 Q9BJF5 TAIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEAKKMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSETKELEHEVDVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN 5dvt A 2.05 BS01 5GB A 1 L57 G60 S61 V65 A78 K80 M112 L114 L126 E129 Y131 L181 I194 D195 L13 G16 S17 V21 A34 K36 M66 L68 L80 E83 Y85 L135 I148 D149 Q9BJF5 AIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSTKELLDRAELASHEVDQVLDVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN 5dvu A 2.05 BS01 5GA A 1 L57 S61 V65 A78 M112 L126 E129 Y131 L181 I194 D195 L12 S14 V18 A31 M63 L77 E80 Y82 L132 I145 D146 Q9BJF5 IFSDRYKGQRVLGSFGEVILCKDKITGQECAVKVISKVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSETKELRAELIEGYKHEVDQVLVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN