3jb9 A 3.60 BS01 NUC C 1 K69 Q76 E78 H118 K122 S153 R155 G241 P242 T243 R245 K286 F298 E299 L301 H432 R443 D446 K451 K475 M479 N480 K481 L482 H483 H486 P487 K488 S489 H490 T491 N492 R497 K500 N501 K618 Y619 R620 R623 Q624 R658 F662 R665 G666 P669 A788 V790 D791 K1318 R1322 K23 Q30 E32 H72 K76 S107 R109 G195 P196 T197 R199 K240 F252 E253 L255 H375 R386 D389 K394 K418 M422 N423 K424 L425 H426 H429 P430 K431 S432 H433 T434 N435 R440 K443 N444 K561 Y562 R563 R566 Q567 R601 F605 R608 G609 P612 A731 V733 D734 K1261 R1265 O14187 26292707 LEKQLNERARKWRASQKSKFGVKRKQGYVQTEKADLPPEHLRKIMKDRGDMSSRKFRADKRSYLGALKYLPHAVLKLLENMPMPWEEYREVKVLYHVTGAITFVNESPRVIEPHFIAQWGTMWMMMRREKRDRKNFKRLRFPPFDDEEPPFSIDQLLDLEPLEAIRMDLDEEDDAPVMDWFYENKALEDTPHVNGPTYRRWKLNLPQMANLHRLGYQLLSDLRDDNYFYLFNDNSFFTAKALNVAIPGGPKFEPLYEFNDIYKLIIRHPIKTEYRIAFPYLYNSRARSVALSEYHQPSNVFVPPEDPDLPAFFWDPIINPITSRQLTLHELDTSPEDSAIEEDPNFEIPFDPFFHSEDIEFEHTASALILLWAPHPFNKRSGATKRAQDVPLIKHWYLEHCPPNQPVKVRVSYQKLLKSHVMNKLHMAHPKSHTNRSLLRQLKNTKFFQSTSIDWVEAGLQVCRQGYNMLQLLIHRKGLTYLHLDYNCNLKPTKTLTTKERKKSRFGNAFHLMREILRLTKLIVDSHVQYRLGNIDAYQLADGLHYIFNHVGQLTGMYRYKYRLMRQIRACKDFKHLIYYRFNTGPVGKGPGCGFWAPSWRVWLFFLRGIVPLLERWLGNLLARQFEGRHSTGVAKQITKQRVDSHQDLELRAAVMNDILDMIPEGIRQGKSKTILQHLSEAWRCWKANIPWKVPGLPAPIENMILRYVKSKADWWTSVAHFNRERIRRGATVDKTVAKKNLGRLTRLWLKAEQERQHNYLKDGPYVTADEAVAIYTTFVHWLESRRFQPIPFPPLSYKHDTKLLVLALERLKEAYSVKGRLNQSQREELALVEQAYDNPHEMLSQIKRRLLTMRTFKEVGIEFMDMYSHLIPVYSVDPMEKICDAYLDQYLWFEADRRHLFPSWVKPSDSEPPPLLVYKWCQGINNLTDVWETSNGECNVLMETRLSKVFEKVDLTLLNRLMSLLMDTNLASYASAKNNVVLSYKDMSHTNSYGLVRGLQFSSFIWQFYGLVLDLLILGLQRATEIAGPADAPNDFLHFKDQATETSHPIRLYTRYIDKVYIMFRFTDEESRDLIQRFLNENPDPTNSNVVNYSKGKKNCWPRDARMRLMKHDVNLGRAVFWEIRNRLPRSLTTLEWEDTFPSVYSKDNPNLLFSMTGFEVRILPKIRQNEEFSLKDGVWNLTDNRTKQRTAQAFIRVTEDGINQFGNRIRQILMSSGSTTFTKIANKWNTALIALMTYYREAAISTPELLDLLVKCESKIQTRVKISLNSKMPSRFPPAVFYSPKELGGLGMLSMGHVLIPQSDLRWSKQTDTGITHFRSGMTTNGEHLIPNLYRYIQPWESEFIDSQRVWAEYAMKRQEALQQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTEFKQYQLLKNNPFWWTSQRHDGKLWQLNNYRVDVIQALGGVEGILEHTMFKATGFPSWEGLFWEKASGFKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIMMHGKIPTLKISLIQIFRSHLWQKIHESVVWDLCQVLDQELESLQIETVQKETIHPRKSYKMNSSCADILLLAAYKWNVSRPSLLNDNRDVLDNTTTNKYWIDVQLRFGDYDSHDIERYTRAKFLDYSTDAQSMYPSPTGVLIGIDLCYNMHSAYGNWIPGMKPLIQQSMNKIMKANPALYVLRERIRKGLQLYASEQYLSSSNYAELFSNQIQLFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKVIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPRQIIVTRKGMLDPLEVHLLDFPNITIKGSELQLPFQAIIKLDKINDLILRATEPQMVLFNLYDDWLQSVSSYTAFSRLILILRALNVNTEKTKLILRPDKSIITKENHVWPNLDDQQWLDVEPKLRDLILADYAKKNNINVASLTNSE 3jb9 A 3.60 BS02 NUC N 1 N52 R56 K63 R70 V75 R100 R103 K503 K534 E557 K559 R562 G564 N565 A566 W674 N677 L678 R681 R686 T689 A692 K693 Q694 T696 Q698 R699 S702 L706 K1541 T1543 N1544 N6 R10 K17 R24 V29 R54 R57 K446 K477 E500 K502 R505 G507 N508 A509 W617 N620 L621 R624 R629 T632 A635 K636 Q637 T639 Q641 R642 S645 L649 K1478 T1480 N1481 O14187 26292707 LEKQLNERARKWRASQKSKFGVKRKQGYVQTEKADLPPEHLRKIMKDRGDMSSRKFRADKRSYLGALKYLPHAVLKLLENMPMPWEEYREVKVLYHVTGAITFVNESPRVIEPHFIAQWGTMWMMMRREKRDRKNFKRLRFPPFDDEEPPFSIDQLLDLEPLEAIRMDLDEEDDAPVMDWFYENKALEDTPHVNGPTYRRWKLNLPQMANLHRLGYQLLSDLRDDNYFYLFNDNSFFTAKALNVAIPGGPKFEPLYEFNDIYKLIIRHPIKTEYRIAFPYLYNSRARSVALSEYHQPSNVFVPPEDPDLPAFFWDPIINPITSRQLTLHELDTSPEDSAIEEDPNFEIPFDPFFHSEDIEFEHTASALILLWAPHPFNKRSGATKRAQDVPLIKHWYLEHCPPNQPVKVRVSYQKLLKSHVMNKLHMAHPKSHTNRSLLRQLKNTKFFQSTSIDWVEAGLQVCRQGYNMLQLLIHRKGLTYLHLDYNCNLKPTKTLTTKERKKSRFGNAFHLMREILRLTKLIVDSHVQYRLGNIDAYQLADGLHYIFNHVGQLTGMYRYKYRLMRQIRACKDFKHLIYYRFNTGPVGKGPGCGFWAPSWRVWLFFLRGIVPLLERWLGNLLARQFEGRHSTGVAKQITKQRVDSHQDLELRAAVMNDILDMIPEGIRQGKSKTILQHLSEAWRCWKANIPWKVPGLPAPIENMILRYVKSKADWWTSVAHFNRERIRRGATVDKTVAKKNLGRLTRLWLKAEQERQHNYLKDGPYVTADEAVAIYTTFVHWLESRRFQPIPFPPLSYKHDTKLLVLALERLKEAYSVKGRLNQSQREELALVEQAYDNPHEMLSQIKRRLLTMRTFKEVGIEFMDMYSHLIPVYSVDPMEKICDAYLDQYLWFEADRRHLFPSWVKPSDSEPPPLLVYKWCQGINNLTDVWETSNGECNVLMETRLSKVFEKVDLTLLNRLMSLLMDTNLASYASAKNNVVLSYKDMSHTNSYGLVRGLQFSSFIWQFYGLVLDLLILGLQRATEIAGPADAPNDFLHFKDQATETSHPIRLYTRYIDKVYIMFRFTDEESRDLIQRFLNENPDPTNSNVVNYSKGKKNCWPRDARMRLMKHDVNLGRAVFWEIRNRLPRSLTTLEWEDTFPSVYSKDNPNLLFSMTGFEVRILPKIRQNEEFSLKDGVWNLTDNRTKQRTAQAFIRVTEDGINQFGNRIRQILMSSGSTTFTKIANKWNTALIALMTYYREAAISTPELLDLLVKCESKIQTRVKISLNSKMPSRFPPAVFYSPKELGGLGMLSMGHVLIPQSDLRWSKQTDTGITHFRSGMTTNGEHLIPNLYRYIQPWESEFIDSQRVWAEYAMKRQEALQQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTEFKQYQLLKNNPFWWTSQRHDGKLWQLNNYRVDVIQALGGVEGILEHTMFKATGFPSWEGLFWEKASGFKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIMMHGKIPTLKISLIQIFRSHLWQKIHESVVWDLCQVLDQELESLQIETVQKETIHPRKSYKMNSSCADILLLAAYKWNVSRPSLLNDNRDVLDNTTTNKYWIDVQLRFGDYDSHDIERYTRAKFLDYSTDAQSMYPSPTGVLIGIDLCYNMHSAYGNWIPGMKPLIQQSMNKIMKANPALYVLRERIRKGLQLYASEQYLSSSNYAELFSNQIQLFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKVIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPRQIIVTRKGMLDPLEVHLLDFPNITIKGSELQLPFQAIIKLDKINDLILRATEPQMVLFNLYDDWLQSVSSYTAFSRLILILRALNVNTEKTKLILRPDKSIITKENHVWPNLDDQQWLDVEPKLRDLILADYAKKNNINVASLTNSE 3jb9 A 3.60 BS03 NUC O 1 T554 T555 K556 K559 T497 T498 K499 K502 O14187 26292707 LEKQLNERARKWRASQKSKFGVKRKQGYVQTEKADLPPEHLRKIMKDRGDMSSRKFRADKRSYLGALKYLPHAVLKLLENMPMPWEEYREVKVLYHVTGAITFVNESPRVIEPHFIAQWGTMWMMMRREKRDRKNFKRLRFPPFDDEEPPFSIDQLLDLEPLEAIRMDLDEEDDAPVMDWFYENKALEDTPHVNGPTYRRWKLNLPQMANLHRLGYQLLSDLRDDNYFYLFNDNSFFTAKALNVAIPGGPKFEPLYEFNDIYKLIIRHPIKTEYRIAFPYLYNSRARSVALSEYHQPSNVFVPPEDPDLPAFFWDPIINPITSRQLTLHELDTSPEDSAIEEDPNFEIPFDPFFHSEDIEFEHTASALILLWAPHPFNKRSGATKRAQDVPLIKHWYLEHCPPNQPVKVRVSYQKLLKSHVMNKLHMAHPKSHTNRSLLRQLKNTKFFQSTSIDWVEAGLQVCRQGYNMLQLLIHRKGLTYLHLDYNCNLKPTKTLTTKERKKSRFGNAFHLMREILRLTKLIVDSHVQYRLGNIDAYQLADGLHYIFNHVGQLTGMYRYKYRLMRQIRACKDFKHLIYYRFNTGPVGKGPGCGFWAPSWRVWLFFLRGIVPLLERWLGNLLARQFEGRHSTGVAKQITKQRVDSHQDLELRAAVMNDILDMIPEGIRQGKSKTILQHLSEAWRCWKANIPWKVPGLPAPIENMILRYVKSKADWWTSVAHFNRERIRRGATVDKTVAKKNLGRLTRLWLKAEQERQHNYLKDGPYVTADEAVAIYTTFVHWLESRRFQPIPFPPLSYKHDTKLLVLALERLKEAYSVKGRLNQSQREELALVEQAYDNPHEMLSQIKRRLLTMRTFKEVGIEFMDMYSHLIPVYSVDPMEKICDAYLDQYLWFEADRRHLFPSWVKPSDSEPPPLLVYKWCQGINNLTDVWETSNGECNVLMETRLSKVFEKVDLTLLNRLMSLLMDTNLASYASAKNNVVLSYKDMSHTNSYGLVRGLQFSSFIWQFYGLVLDLLILGLQRATEIAGPADAPNDFLHFKDQATETSHPIRLYTRYIDKVYIMFRFTDEESRDLIQRFLNENPDPTNSNVVNYSKGKKNCWPRDARMRLMKHDVNLGRAVFWEIRNRLPRSLTTLEWEDTFPSVYSKDNPNLLFSMTGFEVRILPKIRQNEEFSLKDGVWNLTDNRTKQRTAQAFIRVTEDGINQFGNRIRQILMSSGSTTFTKIANKWNTALIALMTYYREAAISTPELLDLLVKCESKIQTRVKISLNSKMPSRFPPAVFYSPKELGGLGMLSMGHVLIPQSDLRWSKQTDTGITHFRSGMTTNGEHLIPNLYRYIQPWESEFIDSQRVWAEYAMKRQEALQQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTEFKQYQLLKNNPFWWTSQRHDGKLWQLNNYRVDVIQALGGVEGILEHTMFKATGFPSWEGLFWEKASGFKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIMMHGKIPTLKISLIQIFRSHLWQKIHESVVWDLCQVLDQELESLQIETVQKETIHPRKSYKMNSSCADILLLAAYKWNVSRPSLLNDNRDVLDNTTTNKYWIDVQLRFGDYDSHDIERYTRAKFLDYSTDAQSMYPSPTGVLIGIDLCYNMHSAYGNWIPGMKPLIQQSMNKIMKANPALYVLRERIRKGLQLYASEQYLSSSNYAELFSNQIQLFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKVIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPRQIIVTRKGMLDPLEVHLLDFPNITIKGSELQLPFQAIIKLDKINDLILRATEPQMVLFNLYDDWLQSVSSYTAFSRLILILRALNVNTEKTKLILRPDKSIITKENHVWPNLDDQQWLDVEPKLRDLILADYAKKNNINVASLTNSE 3jb9 A 3.60 BS04 NUC P 1 D701 D705 R709 R725 K730 T731 Q734 W740 K796 K797 R801 R804 N880 Q881 R884 K1043 D1044 D644 D648 R652 R668 K673 T674 Q677 W683 K739 K740 R744 R747 N823 Q824 R827 K986 D987 O14187 26292707 LEKQLNERARKWRASQKSKFGVKRKQGYVQTEKADLPPEHLRKIMKDRGDMSSRKFRADKRSYLGALKYLPHAVLKLLENMPMPWEEYREVKVLYHVTGAITFVNESPRVIEPHFIAQWGTMWMMMRREKRDRKNFKRLRFPPFDDEEPPFSIDQLLDLEPLEAIRMDLDEEDDAPVMDWFYENKALEDTPHVNGPTYRRWKLNLPQMANLHRLGYQLLSDLRDDNYFYLFNDNSFFTAKALNVAIPGGPKFEPLYEFNDIYKLIIRHPIKTEYRIAFPYLYNSRARSVALSEYHQPSNVFVPPEDPDLPAFFWDPIINPITSRQLTLHELDTSPEDSAIEEDPNFEIPFDPFFHSEDIEFEHTASALILLWAPHPFNKRSGATKRAQDVPLIKHWYLEHCPPNQPVKVRVSYQKLLKSHVMNKLHMAHPKSHTNRSLLRQLKNTKFFQSTSIDWVEAGLQVCRQGYNMLQLLIHRKGLTYLHLDYNCNLKPTKTLTTKERKKSRFGNAFHLMREILRLTKLIVDSHVQYRLGNIDAYQLADGLHYIFNHVGQLTGMYRYKYRLMRQIRACKDFKHLIYYRFNTGPVGKGPGCGFWAPSWRVWLFFLRGIVPLLERWLGNLLARQFEGRHSTGVAKQITKQRVDSHQDLELRAAVMNDILDMIPEGIRQGKSKTILQHLSEAWRCWKANIPWKVPGLPAPIENMILRYVKSKADWWTSVAHFNRERIRRGATVDKTVAKKNLGRLTRLWLKAEQERQHNYLKDGPYVTADEAVAIYTTFVHWLESRRFQPIPFPPLSYKHDTKLLVLALERLKEAYSVKGRLNQSQREELALVEQAYDNPHEMLSQIKRRLLTMRTFKEVGIEFMDMYSHLIPVYSVDPMEKICDAYLDQYLWFEADRRHLFPSWVKPSDSEPPPLLVYKWCQGINNLTDVWETSNGECNVLMETRLSKVFEKVDLTLLNRLMSLLMDTNLASYASAKNNVVLSYKDMSHTNSYGLVRGLQFSSFIWQFYGLVLDLLILGLQRATEIAGPADAPNDFLHFKDQATETSHPIRLYTRYIDKVYIMFRFTDEESRDLIQRFLNENPDPTNSNVVNYSKGKKNCWPRDARMRLMKHDVNLGRAVFWEIRNRLPRSLTTLEWEDTFPSVYSKDNPNLLFSMTGFEVRILPKIRQNEEFSLKDGVWNLTDNRTKQRTAQAFIRVTEDGINQFGNRIRQILMSSGSTTFTKIANKWNTALIALMTYYREAAISTPELLDLLVKCESKIQTRVKISLNSKMPSRFPPAVFYSPKELGGLGMLSMGHVLIPQSDLRWSKQTDTGITHFRSGMTTNGEHLIPNLYRYIQPWESEFIDSQRVWAEYAMKRQEALQQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTEFKQYQLLKNNPFWWTSQRHDGKLWQLNNYRVDVIQALGGVEGILEHTMFKATGFPSWEGLFWEKASGFKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIMMHGKIPTLKISLIQIFRSHLWQKIHESVVWDLCQVLDQELESLQIETVQKETIHPRKSYKMNSSCADILLLAAYKWNVSRPSLLNDNRDVLDNTTTNKYWIDVQLRFGDYDSHDIERYTRAKFLDYSTDAQSMYPSPTGVLIGIDLCYNMHSAYGNWIPGMKPLIQQSMNKIMKANPALYVLRERIRKGLQLYASEQYLSSSNYAELFSNQIQLFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKVIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPRQIIVTRKGMLDPLEVHLLDFPNITIKGSELQLPFQAIIKLDKINDLILRATEPQMVLFNLYDDWLQSVSSYTAFSRLILILRALNVNTEKTKLILRPDKSIITKENHVWPNLDDQQWLDVEPKLRDLILADYAKKNNINVASLTNSE 3jb9 B 3.60 BS01 NUC C 1 I116 E117 T118 T119 R174 Y184 R187 K405 Y414 R550 I49 E50 T51 T52 R107 Y117 R120 K338 Y347 R483 O94316 26292707 AVVLHEDKQYYPSAEEVYGSNVDIMVQEQDTQPLSQPIIEPIRHKRIAIETTNVPDTVYKKEFLFGLLTGTDDVRSFIVAGHLHHGKSALLDLLVYYTHPDTKPPKRRSLRYTDTHYLERERVMSIKSTPLTLAVSDMKGKTFAFQCIDTPGHVDFVDEVAAPMAISDGVVLVVDVIEGVMINTTRIIKHAILHDMPIVLVLNKVDRLILELRLPPNDAYHKLRHVIDEVNDNICQISKDLKYRVSPELGNVCFASCDLGYCFTLSSFAKLYIDRHGGIDVDLFSKRLWGDIYFDSKTRKFAKQSLDGSGVRSFVHFILEPLYKLHTLTISDEAEKLKKHLSSFQIYLKPKDYLLDPKPLLQLICASFFGFPVGFVNAVTRHIPSPRENAARKASQSYIGPINSSIGKAILEMSREESAPLVMHVTKLYNTVDANNFYAFARVYSGQVKKGQKVKVLGENYSLEDEEDMVVAHIAEICVPCARYRLHVDGAVAGMLVLLGGVDNSISKTATIVSDNLKDDPYIFRPIAHMSESVFKVAVEPHNPSELPKLLDGLRKTNKSYPLSITKVEESGEHTIFGTGEMYMDCLLYDLRTLYSEIEIRVSDPVARFCETAVDTSSIKCFSDTPNKKNRITMVVEPLEKGISNDIENGKVNINWPQKRISEFFQKNYDWDLLASRSIWAFGPDDRGTNILRDDTLSTDVDKNVLNSVKEYIKQGFQWGTREGPLCDETIRNVNFRLMDVVLAPEQIYRGGGQIIPTARRVCYSSFLTASPRLMEPVYMVEVHAPADSLPIIYDLLTRRRGHVLQDIPRPGSPLYLVRALIPVIDSCGFETDLRVHTQGQAMCQMVFDHWQVVPGDPLDKSIKPKPLEPARGSDLARDFLIKTRRRKGLVEDVSTTRYFDQEM 3jb9 B 3.60 BS02 GDP B 1 G153 K154 S155 A156 S192 N270 K271 D273 R274 S323 C324 D325 G86 K87 S88 A89 S125 N203 K204 D206 R207 S256 C257 D258 O94316 26292707 AVVLHEDKQYYPSAEEVYGSNVDIMVQEQDTQPLSQPIIEPIRHKRIAIETTNVPDTVYKKEFLFGLLTGTDDVRSFIVAGHLHHGKSALLDLLVYYTHPDTKPPKRRSLRYTDTHYLERERVMSIKSTPLTLAVSDMKGKTFAFQCIDTPGHVDFVDEVAAPMAISDGVVLVVDVIEGVMINTTRIIKHAILHDMPIVLVLNKVDRLILELRLPPNDAYHKLRHVIDEVNDNICQISKDLKYRVSPELGNVCFASCDLGYCFTLSSFAKLYIDRHGGIDVDLFSKRLWGDIYFDSKTRKFAKQSLDGSGVRSFVHFILEPLYKLHTLTISDEAEKLKKHLSSFQIYLKPKDYLLDPKPLLQLICASFFGFPVGFVNAVTRHIPSPRENAARKASQSYIGPINSSIGKAILEMSREESAPLVMHVTKLYNTVDANNFYAFARVYSGQVKKGQKVKVLGENYSLEDEEDMVVAHIAEICVPCARYRLHVDGAVAGMLVLLGGVDNSISKTATIVSDNLKDDPYIFRPIAHMSESVFKVAVEPHNPSELPKLLDGLRKTNKSYPLSITKVEESGEHTIFGTGEMYMDCLLYDLRTLYSEIEIRVSDPVARFCETAVDTSSIKCFSDTPNKKNRITMVVEPLEKGISNDIENGKVNINWPQKRISEFFQKNYDWDLLASRSIWAFGPDDRGTNILRDDTLSTDVDKNVLNSVKEYIKQGFQWGTREGPLCDETIRNVNFRLMDVVLAPEQIYRGGGQIIPTARRVCYSSFLTASPRLMEPVYMVEVHAPADSLPIIYDLLTRRRGHVLQDIPRPGSPLYLVRALIPVIDSCGFETDLRVHTQGQAMCQMVFDHWQVVPGDPLDKSIKPKPLEPARGSDLARDFLIKTRRRKGLVEDVSTTRYFDQEM 3jb9 D 3.60 BS01 NUC C 1 N36 N38 R62 G63 K82 P85 R97 N35 N37 R61 G62 K81 P84 R96 Q9UUC6 26292707 SLCIKLLHETQGHIVTMELENGSTYRGKLIEAEDNMNCQMRDISVTARDGRVSHLDQVYIRGSHIRFLIVPDMLRNAPMFKVGPGRSVPLPTRGRR 3jb9 E 3.60 BS01 NUC C 1 G2 T3 A30 F31 G33 F34 M35 N36 R71 G72 E73 G1 T2 A29 F30 G32 F33 M34 N35 R58 G59 E60 Q10163 26292707 GTTKMVSLLNHSLNVTTKDGRTFVGQLLAFDGFMNLVLSDCQEYRHEEKRMLGLVILRGEFIVSLSVQGPPPMLLSGPGVARPAGRGIPLGQAPVGLA 3jb9 F 3.60 BS01 NUC C 1 K2 K20 Q35 N37 R61 N63 R66 K2 K20 Q35 N37 R61 N63 R66 26292707 MKLVRFLMKLTNETVSIELKNGTIVHGTITSVDMQMNTHLKAVKMTVKGREPVPVETLSIRGNNIRYYILPDSLPLDTLLID 3jb9 G 3.60 BS01 NUC C 1 R48 N50 H63 N65 R102 G103 D104 R30 N32 H45 N47 R82 G83 D84 O14036 26292707 RLEEYEFSAGPLSVLQQAVKNHDQVLINCRNNKKLLARVKAFDRHSNMVLENVKEMWTEKKRTASGGKAINKDRFISKMFLRGDGVVLVVRIPSA 3jb9 H 3.60 BS01 NUC C 1 F31 E32 Q33 F48 M49 F23 E24 Q25 F40 M41 Q9USZ3 26292707 MIPPINFIFKLLQQHTPVSIWLFEQTDIRLQGQIRGFDEFMNIVLDDAVQVDAKNNKRELGRILLKGDNITLIQAI 3jb9 I 3.60 BS01 NUC C 1 K25 W26 S39 Y40 M41 R66 N68 K22 W23 S36 Y37 M38 R63 N65 O59734 26292707 VPVNPKPFLQGLIGKPVLVRLKWGQEYKGTLQSVDSYMNLQLLNAEELVDGVKTGDLGEILIRCNNVLWVGEV 3jb9 J 3.60 BS01 NUC C 1 I36 F37 L38 N39 R63 G64 N65 I34 F35 L36 N37 R61 G62 N63 O74966 26292707 KAGAPDLKKYLDRQVFVQLNGSRKVYGVLRGYDIFLNIVLEDSIEEKVDGEKVKIGSVAIRGNSVIMIETLDK 3jb9 K 3.60 BS01 NUC C 1 K238 H242 K141 H145 O13615 26292707 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGWHAPWTLMRVISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGKTLTTLTHHKKTVRALSLHPDEFTFASGSSDNIKHWKFPEGAFMGNFEGHNAIVNTLSINSDNVMFSGADNGSMCFWDWKSGHKYQELQSVVQPGSLDSEAGIFASSFDKTGLRLITCEADKSVKIYKQVDNATPETHPNLPWTPSNLR 3jb9 L 3.60 BS01 NUC C 1 R72 K93 K130 K132 K168 R31 K51 K88 K90 K125 O94620 26292707 PNLQMFGHTAEVLVARFDPSGSYFASGGMDRQILLWNVFDVKNYGVLNGCKGAITDLQWSRDSRVVYCSSSDTHLMSWDAVSGQKIRKHKGHAGVVNALDVLKVSELLTSVSDDCTMKVWDSRSKDCIKTIEEKYPLTAVAIAQQGTQVFIGGIDGAIKIWDLRNNHCSHVLKGHKDIITSLAISKDGSSLLSNSMDNTVRIFDVKAQRQLQIFEGAIHGQEHNLLGVAWSRNSRFVGAGSSDKNVYVWSATGDLRYVLPGHEGSVNHVDFHPHQDIILSCSSDRTIFLGELN 3jb9 M 3.60 BS01 NUC N 1 A207 E208 K221 P223 N260 P261 K262 A108 E109 K122 P124 N161 P162 K163 Q09882 26292707 AVDYNAIARQGHEHGELVQASFRDLIPLRARLGVGEISLEKPSDEQKQEVANKTKLALQKILSKQIAQSQPKSAVVQQRDDPVYIRYTPSNQMGQALSKQRIIKMVTAEQDPMEPPKFRHKKVPRGPPSPPPPVLHSPPRKVSAQEQQDWQIPPSISNWKNPKGYTIPLDKRDVEINDGFAKFSEALYTVERQAREEVRYRAIMRQK 3jb9 M 3.60 BS02 NUC P 1 P253 K259 N260 P261 K262 Y264 P154 K160 N161 P162 K163 Y165 Q09882 26292707 AVDYNAIARQGHEHGELVQASFRDLIPLRARLGVGEISLEKPSDEQKQEVANKTKLALQKILSKQIAQSQPKSAVVQQRDDPVYIRYTPSNQMGQALSKQRIIKMVTAEQDPMEPPKFRHKKVPRGPPSPPPPVLHSPPRKVSAQEQQDWQIPPSISNWKNPKGYTIPLDKRDVEINDGFAKFSEALYTVERQAREEVRYRAIMRQK 3jb9 W 3.60 BS01 NUC N 1 Y24 R31 S34 R169 N172 T173 K176 K177 R180 Y221 Y17 R24 S27 R118 N121 T122 K125 K126 R129 Y153 P39964 26292707 AWKNTEDEILKAAVSKYGKNQWARISSLLVRKTPKQCKARWYEWIDPSIKKTEWSREEDEKLLHLAKLLPTQWRTIAPIVGRTATQCLERYQKLLDDLEAKEDMDEDEKEMLSEARARLANTQGKKAKRKDREKQLELTRRLSHLQKRRELKYNASIPFEKKPAIGFYGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAAEKFYTNDIQRDLAKKALECNKLENRVYDLVRSSYEQRNFLIKKISHAWKALQTERKNLTCYEFLYNQERLALPNRLEAAEIELSKMQQIEAYAQQDYARVTGQN 3jb9 Y 3.60 BS01 NUC N 1 R57 Y60 Y71 Y75 N76 K77 S79 G81 R83 Q84 Q90 V91 F116 C117 L118 Y119 C125 S126 Y133 F151 R153 H156 Y159 R160 V166 H232 N242 V243 R244 R9 Y12 Y23 Y27 N28 K29 S31 G33 R35 Q36 Q42 V43 F68 C69 L70 Y71 C77 S78 Y85 F103 R105 H108 Y111 R112 V118 H184 N191 V192 R193 P87126 26292707 PARKQIETRPEYEMEPEQPGQVYNLWYNKWSGGMRQDPLKSQVKSETRCVISRDSGYTKADKNPGSFFCLYFARGMCSEGSKCEYLHRLPKDTDFFNANVDCFGREKHADYRDDMGGVGSFLRQNYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVLNSRGIAFITYLNEANAQFAKEAMAHQSLECLNVRWATTDPNPASQARNQRRLEERAANAVKKLLPKQFLLDLEETKNGKGGGGGGGGGGGGGGGGGGGGGGG 3jb9 Y 3.60 BS02 ZN Y 1 C117 C125 C131 H135 C69 C77 C83 H87 P87126 26292707 PARKQIETRPEYEMEPEQPGQVYNLWYNKWSGGMRQDPLKSQVKSETRCVISRDSGYTKADKNPGSFFCLYFARGMCSEGSKCEYLHRLPKDTDFFNANVDCFGREKHADYRDDMGGVGSFLRQNYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVLNSRGIAFITYLNEANAQFAKEAMAHQSLECLNVRWATTDPNPASQARNQRRLEERAANAVKKLLPKQFLLDLEETKNGKGGGGGGGGGGGGGGGGGGGGGGG 3jb9 a 3.60 BS01 NUC N 1 R34 R55 R17 R38 O59800 26292707 EFPSICERCLGDNSYVRMTKEPLGQECKICSKPCTIFRWIKERGQKPGKTQICVGCARYKNCCQSCMLDLQFGLPIALRDAALKLVESGPTNDINREFFAQNQQRLLSNGETAYDSQEASAAARNLVKKVEKREGGGGGGGGGGGGGGASLNAERADYKIRKHFEQYGPLKSVVCSHRAKCAFVNFKTRSSAEIAAAASPDGNVLKVQWGKGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 3jb9 a 3.60 BS02 ZN a 1 C44 C47 C70 C73 C27 C30 C53 C56 O59800 26292707 EFPSICERCLGDNSYVRMTKEPLGQECKICSKPCTIFRWIKERGQKPGKTQICVGCARYKNCCQSCMLDLQFGLPIALRDAALKLVESGPTNDINREFFAQNQQRLLSNGETAYDSQEASAAARNLVKKVEKREGGGGGGGGGGGGGGASLNAERADYKIRKHFEQYGPLKSVVCSHRAKCAFVNFKTRSSAEIAAAASPDGNVLKVQWGKGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 3jb9 c 3.60 BS01 NUC Q 1 K351 Y352 Y356 K360 K364 D401 K404 K18 Y19 Y23 K27 K31 D68 K71 Q09909 26292707 PTIDEMVQEEKLLNKQRKYGQNYEYAKQIAKDKTYSNNLDYLDENAGKLSNRMKRGDVSLAQISSGGDLKKINHVLDTCPLCLNYETQPLAPVISLSHRAYVSLPTQPELAKYHCLIVPTGHRINTLSCDEDEWDEIRNFMKCIALMFDSMNLGVIFYENAPSPQRYMHTAIECIPVSKRILSLAPAYFREALSTSDEEWSQHRKIIDTLEGSKKYGKWAFRKMMVKELGYFHVWFSIDGGYGHVVEDEKAWGRHDQVPRQVFASMLNLPPEVIRRKGSWTGKKDPREDMFRSRFEKFDW 3jb9 c 3.60 BS02 ZN c 1 C412 L414 C415 H455 H502 C79 L81 C82 H122 H169 Q09909 26292707 PTIDEMVQEEKLLNKQRKYGQNYEYAKQIAKDKTYSNNLDYLDENAGKLSNRMKRGDVSLAQISSGGDLKKINHVLDTCPLCLNYETQPLAPVISLSHRAYVSLPTQPELAKYHCLIVPTGHRINTLSCDEDEWDEIRNFMKCIALMFDSMNLGVIFYENAPSPQRYMHTAIECIPVSKRILSLAPAYFREALSTSDEEWSQHRKIIDTLEGSKKYGKWAFRKMMVKELGYFHVWFSIDGGYGHVVEDEKAWGRHDQVPRQVFASMLNLPPEVIRRKGSWTGKKDPREDMFRSRFEKFDW 3jb9 e 3.60 BS01 NUC C 1 A90 K93 K94 A88 K91 K92 O74772 26292707 RLRTSRTKRPPDGFDEIEPTLIEFQDRMRQIENTMGKGTKTEMLAPIFQLHHQRSRYIYDLYYKREAISTELYNWLLKQNYADGNLIAKWKKPGYEKLCCLRCIQTAESKFGSTCICRVPKSKLDKDQRVRCTHCGCNGCASCD 3jb9 e 3.60 BS02 NUC N 1 K42 P95 G96 E98 S111 K112 S115 T116 C117 I118 R120 V121 P122 K125 Q130 V132 T135 S144 C145 K40 P93 G94 E96 S109 K110 S113 T114 C115 I116 R118 V119 P120 K123 Q128 V130 T133 S142 C143 O74772 26292707 RLRTSRTKRPPDGFDEIEPTLIEFQDRMRQIENTMGKGTKTEMLAPIFQLHHQRSRYIYDLYYKREAISTELYNWLLKQNYADGNLIAKWKKPGYEKLCCLRCIQTAESKFGSTCICRVPKSKLDKDQRVRCTHCGCNGCASCD 3jb9 e 3.60 BS03 ZN e 1 C101 C102 C105 C137 C139 C99 C100 C103 C135 C137 O74772 26292707 RLRTSRTKRPPDGFDEIEPTLIEFQDRMRQIENTMGKGTKTEMLAPIFQLHHQRSRYIYDLYYKREAISTELYNWLLKQNYADGNLIAKWKKPGYEKLCCLRCIQTAESKFGSTCICRVPKSKLDKDQRVRCTHCGCNGCASCD 3jb9 e 3.60 BS04 ZN e 2 C101 C119 C139 C142 C99 C117 C137 C140 O74772 26292707 RLRTSRTKRPPDGFDEIEPTLIEFQDRMRQIENTMGKGTKTEMLAPIFQLHHQRSRYIYDLYYKREAISTELYNWLLKQNYADGNLIAKWKKPGYEKLCCLRCIQTAESKFGSTCICRVPKSKLDKDQRVRCTHCGCNGCASCD 3jb9 g 3.60 BS01 NUC N 1 Y104 S124 T125 K135 Y91 S111 T112 K122 O43071 26292707 ENSQSPNIQPLLHTENLAPAVVDNVKDDLIVSKGGNSRELARNVPVNEMVQPALGPANPFVTKEQDSIKNSITGYAEREYVPNFVFNQEYYANTHAIYGKRNFDDNEATTSTDLKRKSQKIKERREDPGDPSILEGDGAYKGPWAGYG 3jb9 h 3.60 BS01 NUC C 1 S26 R27 P30 A31 H32 L33 S3 R4 P7 A8 H9 L10 P78794 26292707 TSSRALPAHLKLKYRQESQGTEEEVRKQDLREALLRAEAAHFATQEHRRWDEDVVFRNTHKGVDDTPRPGFVNDMLRSEFHKKFLARFVD 3jb9 R 3.60 BS01 NUC N 1 R64 R65 N66 H72 R75 I104 P105 L108 R40 R41 N42 H48 R51 I80 P81 L84 P87312 26292707 GGGGGGGGGGGGGGGGNITDLEELQEFQGRKRKEFEDAIRRNRLAMGHWMRYGQWELDQKEFARARSVFERALDVDSTYIPLWLKYIECEMKNRNINHARNLFDRAVTQLPRVDKLWYKYVYMEEMLGNITGCRQVFERWLKWEPDENCWMSYIRMERRYHENERARGIYERFVVVHPEVTNWLRWARFEEECGNAANVRQVYLAAIDALGQEFLNERFFIAFAKFEIRQKEYERARTIFKYAIDFMPRSKSMELYKEYTHFEKQFGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 3jb9 X 3.60 BS01 ADP X 1 Y725 T726 R751 C752 G753 K754 H755 V756 Y1046 T1066 R1177 Y659 T660 R685 C686 G687 K688 H689 V690 Y962 T982 R1091 O94508 26292707 KKKQIINYANSNWGEGVEFQETMLQCILEAVIVSAKQVLSLLHELKLFENFLWQRVNTEMSLNHINLTCMLLLYKSKYEYITWDLINRFQLFFEKVIEVSLSLNLSEVVYMIQFITLCFQFSNIEKLRKLVYQLTNISILNSLLDKVKYLLHDSSSLTKAFDSYKEKRPVEKFPLHNLLSRWIHSLLIKSISYAQKQEAKVTPLLAIINMSLVLLSAFPTRRFAHPVIEDSCFYTALRMSLYYDSNELFKKMTDDLNYVLKFPFDNTRGNEYEKEQKIRNDELVYYHLQLTLFSDFQLQQRQKLEEITSFLSFNSLKSLCSKCYLRTSFPEKYAIKVDFEFLKNVFINTYDRRLVNDYDEIINFTLKDVLGERSVMDQENSLTNTAIQYLSISFFMRQQSKAYKKLLLRSLYAELLNFSEQYRRLSIKNATKNLNFFSLNNFKVTSVAPLPQFVKCQMGLSRPSALRDLKNSSPFLCLIYISKDMEYKLLHGNALDPLEVTDFTIATICNDDVGMFMQSDSDNKSINVYLSPFYYHSLAGLGEYRPKQLKFNFALVLSNKYWLDLNILVSLLNRAKEFPKWFEDLFLGFGTPDICAFPNANSIYARNLFNTVEQLQSVLPNCHVPSNLSTESLLIKFYTNQNKSADVTASDRHFSNRLYTYNDKQLESILRGSQPGLTMVNGPTRCGKHVLVCKLLEVLQDTSPNDRTVVLSDSNFSMNTLFTLLEKARCFHHLLYLSDEGTLERYGTLSSWISKLPGLLREIGRLAASIQAPGSHDASPDTALYFRDAYIKRLWEKYLNTVDKDSVDAYNRFPFHSYFGDKSKRPIETYNKDNFFDYATKLYGELEYMFQQLEEIRPFGLLRYYEDQELYALCQQSRIIGCTWTSLSTRLGTLKEKGFCFNNLIVMNSQNISESSITSILLSNCEPTGFDRLVLLGNQYNGSLFKRLRYLKSRIIDLNTQYNVRESISSLCSSIYPLDIKTVDSSPNKRLDYGNSGFAHEVQFINVGAFKGSQETEPVSGYKQNLGEAEYAVALFQYMRMLGYPTNEIVICTLYESQVSLLNEIISVRCSHNSFFGQPAFVGTVEKLPKRVNFVIFTTVESKEASDHWNPKTFYKAFSACSYGLYVLCNRDLFRSTRGLEKLWNEIEKTPDKLLLTTGEIYPSSHSSVETFEIENLLHLSNYVVEMTKKRLNTN 3jb9 k 3.60 BS01 NUC P 1 Y7 N9 N10 D13 K14 N16 K17 I37 V38 A39 L40 K41 T42 K44 M45 R46 Q48 H50 K74 Q79 Y80 A81 H82 S83 K84 S85 K86 Y3 N5 N6 D9 K10 N12 K13 I33 V34 A35 L36 K37 T38 K40 M41 R42 Q44 H46 K70 Q75 Y76 A77 H78 S79 K80 S81 K82 Q7LL14 26292707 TLYVNNLNDKINKNDLRTALYMLFSTYGTVVDIVALKTPKMRGQAHVVFFDPSAAAIAMKALKNFIFFGKEMKIQYAHSKSKIIERIVA 3jb9 Z 3.60 BS01 NUC P 1 R27 N36 R49 R62 G63 S64 R26 N35 R48 R61 G62 S63 Q9UUC6 26292707 SLCIKLLHETQGHIVTMELENGSTYRGKLIEAEDNMNCQMRDISVTARDGRVSHLDQVYIRGSHIRFLIVPDMLRNAPMF 3jb9 b 3.60 BS01 NUC P 1 F34 M35 N36 R71 G72 E73 F33 M34 N35 R58 G59 E60 Q10163 26292707 GTTKMVSLLNHSLNVTTKDGRTFVGQLLAFDGFMNLVLSDCQEYRHEEKRMLGLVILRGEFIVSLSVQGPPPMD 3jb9 f 3.60 BS01 NUC P 1 V4 K20 M34 Q35 M36 N37 R61 G62 N63 R66 V4 K20 M34 Q35 M36 N37 R61 G62 N63 R66 O42661 26292707 MKLVRFLMKLTNETVSIELKNGTIVHGTITSVDMQMNTHLKAVKMTVKGREPVPVETLSIRGNNIRYYILPDSLPLDTLLID 3jb9 l 3.60 BS01 NUC P 1 R48 R62 H63 N65 K78 R102 G103 D104 G105 R30 R44 H45 N47 K60 R74 G75 D76 G77 O14036 26292707 RLEEYEFSAGPLSVLQQAVKNHDQVLINCRNNKKLLARVKAFDRHSNMVLENVKEMWTEKAINKDRFISKMFLRGDGVVLVVRIPSA 3jb9 m 3.60 BS01 NUC P 1 E32 Q33 F48 M49 E24 Q25 F40 M41 Q9USZ3 26292707 MIPPINFIFKLLQQHTPVSIWLFEQTDIRLQGQIRGFDEFMNIVLDDAVQVDAKNNKRELGRILLKGDNITLIQAI 3jb9 n 3.60 BS01 NUC P 1 K25 W26 S39 Y40 R66 N68 K22 W23 S36 Y37 R63 N65 O59734 26292707 VPVNPKPFLQGLIGKPVLVRLKWGQEYKGTLQSVDSYMNLQLLNAEELVDGVKTGDLGEILIRCNNVLWVGEV 3jb9 o 3.60 BS01 NUC P 1 R63 N65 R61 N63 26292707 KAGAPDLKKYLDRQVFVQLNGSRKVYGVLRGYDIFLNIVLEDSIEEKVDGEKVKIGSVAIRGNSVIMIETLDK 3x1s A 2.81 BS01 NUC I 1 Y41 R42 P43 T45 R63 R72 R83 Q85 R116 V117 T118 M120 Y3 R4 P5 T7 R25 R34 R45 Q47 R78 V79 T80 M82 P68431 26188507 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 3x1s A 2.81 BS02 NUC J 1 H39 R40 Y41 P43 G44 T45 V46 A47 R49 R63 K64 L65 P66 R69 H1 R2 Y3 P5 G6 T7 V8 A9 R11 R25 K26 L27 P28 R31 P68431 26188507 HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 3x1s C 2.81 BS01 NUC I 1 A14 K15 T16 R17 R20 G28 R32 R42 R77 A1 K2 T3 R4 R7 G15 R19 R29 R64 26188507 AKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 3x1s D 2.81 BS02 NUC J 1 R31 S32 R33 K34 I39 Y40 R1 S2 R3 K4 I9 Y10 P33778 26188507 RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSS 3x1s E 2.81 BS01 NUC I 1 R40 Y41 P43 G44 T45 V46 A47 R49 R63 K64 L65 R69 R83 R3 Y4 P6 G7 T8 V9 A10 R12 R26 K27 L28 R32 R46 P68431 26188507 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 3x1s G 2.81 BS03 MN G 1 G44 A45 G46 A47 G30 A31 G32 A33 P04908 26188507 KTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 3x1s H 2.81 BS03 MN G 1 T90 S91 T58 S59 P33778 26188507 RKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSS 3x1t C 2.81 BS01 NUC I 1 V14 K15 S16 R17 G28 R29 R32 R42 R77 V1 K2 S3 R4 G15 R16 R19 R29 R64 Q8CGP4 26188507 VKSRSSRAGLQFPVGRVHRLLRQGNYAQRIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 3x1t C 2.81 BS02 NUC J 1 V14 R29 R42 I43 G44 A45 K75 T76 R77 V1 R16 R29 I30 G31 A32 K62 T63 R64 Q8CGP4 26188507 VKSRSSRAGLQFPVGRVHRLLRQGNYAQRIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 3x1t G 2.81 BS01 NUC I 1 R29 R35 R42 I43 G44 A45 K75 T76 R77 R16 R22 R29 I30 G31 A32 K62 T63 R64 Q8CGP4 26188507 VKSRSSRAGLQFPVGRVHRLLRQGNYAQRIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK 3x1t G 2.81 BS02 NUC J 1 K15 S16 R17 R29 R32 Q41 K2 S3 R4 R16 R19 Q28 Q8CGP4 26188507 VKSRSSRAGLQFPVGRVHRLLRQGNYAQRIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK 3x1u C 3.25 BS01 NUC I 1 V14 K15 S16 R17 G28 R32 R42 R77 V1 K2 S3 R4 G15 R19 R29 R64 Q8CGP4 26188507 VKSRSSRAGLQFPVGRVHRLLRQGNYAQRIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 3x1u C 3.25 BS02 NUC J 1 V14 R42 I43 G44 A45 K75 T76 R77 V1 R29 I30 G31 A32 K62 T63 R64 Q8CGP4 26188507 VKSRSSRAGLQFPVGRVHRLLRQGNYAQRIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 3x1u F 3.25 BS01 NUC I 1 R35 R45 I46 G48 R78 K79 T80 R20 R30 I31 G33 R63 K64 T65 P62805 26188507 KRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 3x1u G 3.25 BS02 NUC J 1 A12 K13 V14 K15 R17 R20 G28 R29 R32 R42 A2 K3 V4 K5 R7 R10 G18 R19 R22 R32 Q8CGP4 26188507 RAKVKSRSSRAGLQFPVGRVHRLLRQGNYAQRIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK 3x1u H 3.25 BS01 NUC I 1 R33 E35 S36 I39 Y40 R2 E4 S5 I8 Y9 P33778 26188507 SRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 3x1u H 3.25 BS02 NUC J 1 Y42 I54 S56 R86 S87 T88 Y11 I23 S25 R55 S56 T57 P33778 26188507 SRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 3x1v A 2.92 BS01 NUC I 1 H39 R40 Y41 R42 P43 T45 R72 R83 F84 Q85 S86 R116 V117 T118 M120 H2 R3 Y4 R5 P6 T8 R35 R46 F47 Q48 S49 R79 V80 T81 M83 P68431 26188507 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 3x1v C 2.92 BS01 NUC I 1 K13 K15 T16 R17 R32 R42 R77 K1 K3 T4 R5 R20 R30 R65 P04908 26188507 KAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 3x1v D 2.92 BS01 NUC I 1 K30 R31 C32 E35 Y42 G53 I54 S55 S56 R86 S87 T88 K4 R5 C6 E9 Y16 G27 I28 S29 S30 R60 S61 T62 P70696 26188507 RKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 3x1v D 2.92 BS02 NUC J 1 K28 R29 K30 R31 R33 K34 E35 S36 I39 Y40 K2 R3 K4 R5 R7 K8 E9 S10 I13 Y14 P70696 26188507 RKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 3x1v G 2.92 BS02 NUC J 1 R11 A12 A14 K15 T16 R17 R20 R29 R32 R42 R77 R1 A2 A4 K5 T6 R7 R10 R19 R22 R32 R67 P04908 26188507 RAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK 3x1v H 2.92 BS02 NUC J 1 C32 Y42 S56 R86 S87 T88 C1 Y11 S25 R55 S56 T57 P70696 26188507 CRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 4crl A 2.40 BS01 C1I A 1 V27 Y32 V35 A50 I79 D98 A100 D103 W105 H106 A155 L158 R356 V30 Y35 V38 A53 I82 D101 A103 D106 W108 H109 A152 L155 R336 2.7.11.22 P49336 DDKMDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFL 4d6z A 1.93 BS01 HEM A 1 R105 I118 S119 W126 R130 F137 A305 G306 V313 I369 A370 L373 R375 P434 F435 G436 S437 R440 N441 C442 I443 G444 A448 M452 R77 I90 S91 W98 R102 F109 A268 G269 V276 I332 A333 L336 R338 P397 F398 G399 S400 R403 N404 C405 I406 G407 A411 M415 1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.97 P08684 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 4d6z A 1.93 BS02 PK9 A 1 R105 S119 R212 F213 F215 I301 F304 T309 I369 A370 R77 S91 R184 F185 F187 I264 F267 T272 I332 A333 1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.97 P08684 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 4d75 A 2.25 BS01 PK9 A 1 R105 S119 R212 I301 F304 A305 T309 I369 R78 S92 R185 I265 F268 A269 T273 I333 1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.97 P08684 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEHRVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 4d78 A 2.80 BS02 J9K A 1 F108 I120 L211 I301 F304 A305 T309 I369 F82 I94 L185 I264 F267 A268 T272 I332 1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.97 P08684 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTHRVDFLQLMIDSQALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 4d7d A 2.76 BS02 PKT A 1 R105 F108 S119 L210 L211 I301 F304 A305 T309 I369 R77 F80 S91 L182 L183 I263 F266 A267 T271 I331 1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.97 P08684 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTHRVDFLQLMIDSQNALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 4qp1 A 2.70 BS01 EMU A 1 E33 A52 Q105 D106 M108 L156 E22 A41 Q94 D95 M97 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFDDLPKEKLKELIFEETARFQPGYRS 4qp1 A 2.70 BS02 IMD A 1 M108 E109 T110 D111 K114 M97 E98 T99 D100 K103 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFDDLPKEKLKELIFEETARFQPGYRS 4qp1 B 2.70 BS01 EMU B 1 I31 A52 Q105 D106 L107 M108 L156 I20 A41 Q94 D95 L96 M97 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIILKANYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp1 B 2.70 BS02 IMD B 1 M108 T110 D111 K114 M97 T99 D100 K103 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIILKANYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp2 A 2.23 BS01 36R A 1 I31 V39 A52 Q105 D106 M108 L156 I20 V28 A41 Q94 D95 M97 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHYVATRWYRAPEIMLNYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFLDDLPKEKLKELIFEETARFQPGYRS 4qp2 A 2.23 BS02 IMD A 1 M108 E109 T110 D111 K114 L156 M97 E98 T99 D100 K103 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHYVATRWYRAPEIMLNYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFLDDLPKEKLKELIFEETARFQPGYRS 4qp3 A 2.60 BS01 36Q A 1 I31 A52 Q105 D106 M108 E109 T110 D111 K114 L156 I20 A41 Q94 D95 M97 E98 T99 D100 K103 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHYVATRWYRAPEIMLNYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS 4qp3 B 2.60 BS01 36Q B 1 I31 A52 D106 M108 E109 T110 D111 K114 L156 I17 A38 D92 M94 E95 T96 D97 K100 L142 2.7.11.24 P28482 26338362 EGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp4 A 2.20 BS01 36O A 1 I31 A52 K54 D106 M108 E109 T110 D111 K114 L156 I19 A40 K42 D94 M96 E97 T98 D99 K102 L144 2.7.11.24 P28482 26338362 MVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp4 B 2.20 BS01 36O B 1 A52 K54 D106 L107 M108 T110 D111 K114 L156 A41 K43 D95 L96 M97 T99 D100 K103 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVAEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp6 A 3.10 BS01 36N A 1 I31 A52 Q105 D106 M108 L156 I20 A41 Q94 D95 M97 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHYVATRWYRAPEIMLNYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS 4qp6 B 3.10 BS01 36N B 1 A52 I84 Q105 D106 M108 L156 A41 I73 Q94 D95 M97 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp7 A 2.25 BS01 363 A 1 A52 Q105 D106 L107 M108 K114 L156 A40 Q93 D94 L95 M96 K102 L144 2.7.11.24 P28482 26338362 MVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp7 B 2.25 BS01 363 B 1 A52 Q105 D106 L107 M108 D111 K114 L156 A41 Q94 D95 L96 M97 D100 K103 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVAEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp8 A 2.45 BS01 362 A 1 Y36 A52 K54 Q105 D106 L107 M108 T110 D111 K114 L156 Y25 A41 K43 Q94 D95 L96 M97 T99 D100 K103 L145 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVAEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp8 B 2.45 BS01 362 B 1 I31 A52 K54 Q105 D106 L107 M108 D111 K114 L156 C166 I19 A40 K42 Q93 D94 L95 M96 D99 K102 L144 C154 2.7.11.24 P28482 26338362 MVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qp9 A 2.00 BS01 35X A 1 I31 Y36 A52 Q105 D106 M108 E109 D111 K114 L156 C166 D167 I19 Y24 A40 Q93 D94 M96 E97 D99 K102 L144 C154 D155 2.7.11.24 P28482 26338362 MVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFELDDLPKEKLKELIFEETARFQPG 4qpa A 2.85 BS01 35W A 1 G32 V37 A50 K52 Q103 D104 M106 E107 D109 K112 L154 C164 G20 V25 A38 K40 Q91 D92 M94 E95 D97 K100 L142 C152 2.7.11.24 P28482 26338362 EMVRFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4qpa B 2.85 BS01 35W B 1 A33 A50 K52 Q103 M106 D109 K112 L154 C164 A24 A41 K43 Q94 M97 D100 K103 L145 C155 2.7.11.24 P28482 26338362 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFMELDDLPKEKLKELIFEETARFQPGYRS 4rey A 1.96 BS01 III B 1 H18 H20 Q23 Y36 I40 L55 K56 L59 Q93 G94 L95 L96 G97 A98 S99 V100 R101 C103 A108 Q111 W113 V136 V137 G138 S139 D140 I142 L143 E145 E147 L152 M164 H7 H9 Q12 Y25 I29 L44 K45 L48 Q82 G83 L84 L85 G86 A87 S88 V89 R90 C92 A97 Q100 W102 V125 V126 G127 S128 D129 I131 L132 E134 E136 L141 M153 Q9BQQ3 GGAEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEQVWHVLDVEPSSPAALAGLRPYTDYVVGSDQILQESEDFFTLIESHEGKPLKLMVYNSKSDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPP 4rmd A 1.90 BS02 3SW A 1 I268 A271 A272 Q275 W305 F313 R316 L326 A327 V342 F346 V349 C432 H435 L436 I24 A27 A28 Q31 W61 F69 R72 L82 A83 V98 F102 V105 C188 H191 L192 P19793 26331194 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4ru8 A 2.37 BS01 ANP A 1 G13 G14 V15 G16 K17 T18 T19 D41 Q43 P144 R207 L254 S255 S256 R257 K258 L261 S262 G12 G13 V14 G15 K16 T17 T18 D40 Q42 P143 R206 L253 S254 S255 R256 K257 L260 S261 O93708 26339031 IAKVITIHNFKGGVGKTTTTAIIAMGLGAMGKRVLLIDFDAQMSLTQIFVREEDRLKILESSHDVTQDKSAFALLRTMEPARIKFFHEGKGVKFGIDVIPGSYMSIFKLMFEGYIPIQSEWNILRMLDLYRDQYDYILIDTAPSDVVTIKPILRASHYLLIPEDGTPEAFTAMRIFLNEALPKYILPRPEGGFYKYPRILGVILTRVRRNSTAILMKHNKILEEELSNSELKDHVIYPPYFGADKDNPEDYILSSRKEYLSDLIWRDEKRAPISEVFDKLFLVDDKVQKDLYAFFSKVFTEIPKEVVRRVENDQ 4ru8 A 2.37 BS02 MG A 1 T18 D41 D141 T142 T17 D40 D140 T141 O93708 26339031 IAKVITIHNFKGGVGKTTTTAIIAMGLGAMGKRVLLIDFDAQMSLTQIFVREEDRLKILESSHDVTQDKSAFALLRTMEPARIKFFHEGKGVKFGIDVIPGSYMSIFKLMFEGYIPIQSEWNILRMLDLYRDQYDYILIDTAPSDVVTIKPILRASHYLLIPEDGTPEAFTAMRIFLNEALPKYILPRPEGGFYKYPRILGVILTRVRRNSTAILMKHNKILEEELSNSELKDHVIYPPYFGADKDNPEDYILSSRKEYLSDLIWRDEKRAPISEVFDKLFLVDDKVQKDLYAFFSKVFTEIPKEVVRRVENDQ 4ru8 A 2.37 BS03 ANP D 1 K12 G13 T167 E169 K11 G12 T166 E168 O93708 26339031 IAKVITIHNFKGGVGKTTTTAIIAMGLGAMGKRVLLIDFDAQMSLTQIFVREEDRLKILESSHDVTQDKSAFALLRTMEPARIKFFHEGKGVKFGIDVIPGSYMSIFKLMFEGYIPIQSEWNILRMLDLYRDQYDYILIDTAPSDVVTIKPILRASHYLLIPEDGTPEAFTAMRIFLNEALPKYILPRPEGGFYKYPRILGVILTRVRRNSTAILMKHNKILEEELSNSELKDHVIYPPYFGADKDNPEDYILSSRKEYLSDLIWRDEKRAPISEVFDKLFLVDDKVQKDLYAFFSKVFTEIPKEVVRRVENDQ 4ru8 D 2.37 BS02 ANP D 1 G13 G14 G16 K17 T18 T19 D41 Q43 P144 R207 L254 S255 S256 R257 K258 L261 S262 G12 G13 G15 K16 T17 T18 D40 Q42 P143 R206 L253 S254 S255 R256 K257 L260 S261 O93708 26339031 IAKVITIHNFKGGVGKTTTTAIIAMGLGAMGKRVLLIDFDAQMSLTQIFVREEDRLKILESSHDVTQDKSAFALLRTMEPARIKFFHEGKGVKFGIDVIPGSYMSIFKLMFEGYIPIQSEWNILRMLDLYRDQYDYILIDTAPSDVVTIKPILRASHYLLIPEDGTPEAFTAMRIFLNEALPKYILPRPEGGFYKYPRILGVILTRVRRNSTAILMKHNKILEEELSNSELKDHVIYPPYFGADKDNPEDYILSSRKEYLSDLIWRDEKRAPISEVFDKLFLVDDKVQKDLYAFFSKVFTEIPKEVVRRVENDQ 4ru8 D 2.37 BS03 MG D 1 T18 D41 T17 D40 O93708 26339031 IAKVITIHNFKGGVGKTTTTAIIAMGLGAMGKRVLLIDFDAQMSLTQIFVREEDRLKILESSHDVTQDKSAFALLRTMEPARIKFFHEGKGVKFGIDVIPGSYMSIFKLMFEGYIPIQSEWNILRMLDLYRDQYDYILIDTAPSDVVTIKPILRASHYLLIPEDGTPEAFTAMRIFLNEALPKYILPRPEGGFYKYPRILGVILTRVRRNSTAILMKHNKILEEELSNSELKDHVIYPPYFGADKDNPEDYILSSRKEYLSDLIWRDEKRAPISEVFDKLFLVDDKVQKDLYAFFSKVFTEIPKEVVRRVENDQ 4w9y A 1.64 BS04 3K0 A 1 R210 N257 H377 D387 E424 E425 G427 L428 D453 G518 N519 Y552 H553 K699 Y700 R156 N203 H323 D333 E370 E371 G373 L374 D399 G464 N465 Y495 H496 K640 Y641 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4wav A 2.80 BS01 RET A 1 W94 T97 T98 I127 W146 S149 T150 M153 W190 Y193 P194 W197 D220 A223 K224 W83 T86 T87 I116 W135 S138 T139 M142 W179 Y182 P183 W186 D209 A212 K213 G0LFX8 GVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYANWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 4wav A 2.80 BS02 MPG A 1 S177 N184 I185 V188 I192 S166 N173 I174 V177 I181 G0LFX8 GVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYANWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 4wav A 2.80 BS03 MPG A 2 T74 E75 W88 L95 V128 L131 T63 E64 W77 L84 V117 L120 G0LFX8 GVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYANWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 4wav B 2.80 BS01 RET B 1 Y91 W94 T98 M126 I127 G130 W146 S149 T150 M153 W190 Y193 P194 D220 A223 K224 Y81 W84 T88 M116 I117 G120 W136 S139 T140 M143 W180 Y183 P184 D210 A213 K214 G0LFX8 LGVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYANWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRA 4wbr D 1.40 BS01 CU D 1 Y71 C74 C78 H162 Y32 C35 C39 H123 Q89VB6 AIGGPFQLTDQNGKAVTDKSLKGKPTLIFFGYTHCPDVCPTSLFEISEVLRAMGKDADKVNAIFISVDPERDTPATMKNYLSSFDPHLEGLSGDPAEIAKVITSYRVYAKKVPTKDGDYTMDHTALIYLMDRDGRFVSPFNLKRTPEEAAADLKRYL 4wca A 1.85 BS01 CIT A 1 Y168 Q230 T232 F235 H309 T311 P320 V321 Y8 Q63 T65 F68 H142 T144 P153 V154 3.1.4.37 P16330 EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFEKLELVSYFGKRPPGVLQCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 4wcc A 2.70 BS01 2AM A 1 Y168 H230 F235 H309 T311 P320 V321 Y7 H62 F67 H136 T138 P147 V148 3.1.4.37 P16330 KDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFEKLELVSYFGKRGPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLSEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 4wcf A 1.93 BS01 NAP A 1 G10 R14 I15 H33 Y34 H35 N36 S37 A61 D62 L63 T64 N93 A94 S95 T126 L159 C160 D161 K178 P204 G205 V206 S207 L208 G9 R13 I14 H32 Y33 H34 N35 S36 A60 D61 L62 T63 N92 A93 S94 T116 L140 C141 D142 K159 P185 G186 V187 S188 L189 O76290 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4wcf A 1.93 BS02 3KN A 1 S95 F97 D161 Y174 P210 S94 F96 D142 Y155 P191 O76290 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4wcf B 1.93 BS02 3KN B 1 S95 F97 D161 Y174 S94 F96 D141 Y154 O76290 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4wdf A 2.00 BS01 A2P A 1 L167 Y168 H230 T232 F235 H309 T311 P320 A321 L5 Y6 H65 T67 F70 H144 T146 P155 A156 3.1.4.37 P16330 DFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPAQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 4wvg A 2.05 BS01 MAL A 1 D20 K21 W68 A69 D71 R72 E117 E159 P160 Y161 W236 W346 D9 K10 W57 A58 D60 R61 E106 E148 P149 Y150 W225 W335 3.4.21.89 Q5HHB9 MLVIWINGDKGYNGLAQVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAGAIVTPYTIKGEAMDPTLKDGERVAVNIVGYKTGLEKGNVVVFHANNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFW 4wvh A 2.10 BS01 III C 1 T379 P380 Y381 T382 I383 K384 S387 M388 D425 Y426 V427 K428 T369 P370 Y371 T372 I373 K374 S377 M378 D414 Y415 V416 K417 3.4.21.89 HHHMLVIWINGDKGYNGLAQVGKKFEKDTGIKVTVEHPYKLEEKFPQVAGDGPDIIFWAHDRFGGYACSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDGELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAGAIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWSHPQ 4wvi A 1.90 BS01 III D 1 C78 Y105 N106 P380 Y381 T382 I383 K384 S387 M388 D424 D425 Y426 V427 K428 C68 Y95 N96 P370 Y371 T372 I373 K374 S377 M378 D413 D414 Y415 V416 K417 3.4.21.89 Q5HHB9 HHMLVIWINGDKGYNGLAQVGKKFEKDTGIKVTVEHPYKLEEKFPQVAATGGPDIIFWAHDRFGGYACSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDGELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAGAIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWSHPQFE 4wvi A 1.90 BS02 MAL A 1 N18 D20 K21 W68 A69 D71 R72 E117 E159 P160 Y161 F162 W236 W346 N9 D11 K12 W58 A59 D61 R62 E107 E149 P150 Y151 F152 W226 W336 3.4.21.89 Q5HHB9 HHMLVIWINGDKGYNGLAQVGKKFEKDTGIKVTVEHPYKLEEKFPQVAATGGPDIIFWAHDRFGGYACSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDGELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAGAIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWSHPQFE 4wvj A 1.95 BS01 III D 1 C78 G80 Y105 N106 P380 Y381 T382 I383 K384 G385 E386 S387 D424 D425 Y426 V427 K428 V502 S503 K504 C64 G66 Y91 N92 P366 Y367 T368 I369 K370 G371 E372 S373 D409 D410 Y411 V412 K413 V487 S488 K489 3.4.21.89 Q5HHB9 LVIWINGDKGYNGLAQVGKKFEKDTGIKVTVEHPYKLEEKFPQVAATGPDIIFWAHDRFGGYACSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDGELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAGAIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWSHPQ 4wvv A 1.21 BS01 LBT A 1 R44 H64 N66 R68 N78 W85 E88 R36 H56 N58 R60 N70 W77 E80 Q1W2P6 26270612 KKISNPIIPYVGTILGGLVPGELIVLHGSIPDDADRFQVDLQCGSSIKPRADVAFHFNPRFKWSGCVVCNTLEREKWGWEEITYEMPFQKGRPFEIVIMILKDKFQVSVNKKHLLLYNHRISLERIDTLGIYGKVQIKSIEFVSN 4wvw A 1.47 BS01 SLT A 1 R44 Q46 R58 H64 N66 R68 N78 W85 E88 R36 Q38 R50 H56 N58 R60 N70 W77 E80 Q1W2P6 26270612 KKISNPIIPYVGTILGGLVPGELIVLHGSIPDDADRFQVDLQCGSSIKPRADVAFHFNPRFKWSGCVVCNTLEREKWGWEEITYEMPFQKGRPFEIVIMILKDKFQVSVNKKHLLLYNHRISLERIDTLGIYGKVQIKSIEFVS 4x6h A 1.00 BS01 3XT A 1 Q19 G23 C25 W26 D61 G64 G65 G66 Y67 A134 L160 N161 Q19 G23 C25 W26 D61 G64 G65 G66 Y67 A134 L160 N161 3.4.22.38 P43235 26280490 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 4x6s A 2.55 BS01 III L 1 R438 R458 S460 Q461 V468 K478 H479 Y480 L481 M495 D496 D497 Q499 I518 R15 R35 S37 Q38 V45 K55 H56 Y57 L58 M72 D73 D74 Q76 I95 Q14451 26359549 AIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTR 4x6s B 2.55 BS01 III M 1 R438 S460 Q461 V468 K478 H479 Y480 L481 M495 D496 Q499 I518 R16 S38 Q39 V46 K56 H57 Y58 L59 M73 D74 Q77 I96 Q14451 26359549 AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTR 4xh1 A 2.00 BS01 ANP A 1 H175 H203 G205 N206 G207 D278 L279 G325 G326 I327 N330 S331 H171 H199 G201 N202 G203 D274 L275 G321 G322 I323 N326 S327 2.7.2.15 O06961 26249345 FPVVLVINCGSSSIKFSVLDVATCDVLMAGIADGMTENAFLSINGDKPINLAHSNYEDALKAIAFELEKRDLTDSVALIGHRIAHGGELFTQSVIITDEIIDNIRRVSPLAPLHNYANLSGIDAARHLFPAVRQVAVFDTSFHQTLAPEAYLYGLPWEYFSSLGVRRYGFHGTSHRYVSRRAYELLDLDEKDSGLIVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMAWIAKETGQTLSDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERARLAIKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSVLIRQLVIEHLGVLGLTLDVEMNKQPNSHGERIISANPSQVICAVIPTNEEKMIALDAIHLGNVKA 4xh4 A 1.80 BS01 ANP A 1 H175 H203 G205 N206 G207 D278 L279 R280 E283 G326 I327 N330 S331 H172 H200 G202 N203 G204 D275 L276 R277 E280 G323 I324 N327 S328 2.7.2.15 O06961 26249345 FPVVLVINCGSSSIKFSVLDVATCDVLMAGIADGMNTENAFLSINGDKPINLAHSNYEDALKAIAFELEKRDLTDSVALIGHRIVHGGELFTQSVIITDEIIDNIRRVSPLAPLHNYANLSGIDAARHLFPAVRQVAVFDTSFHQTLAPEAYLYGLPWEYFSSLGVRRYGFHGTSHRYVSRRAYELLDLDEKDSGLIVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMAWIAKETGQTLSDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERARLAIKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSVLIRQLVIEHLGVLGLTLDVEMNKQPNSHGERIISANPSQVICAVIPTNEEKMIALDAIHLGNVKA 4xln C 4.00 BS01 NUC O 1 R142 K167 G169 P170 W171 N187 D246 Y256 L260 R266 D326 R331 R353 L418 E421 R422 D426 R136 K161 G163 P164 W165 N181 D240 Y250 L254 R260 D320 R325 R347 L412 E415 R416 D420 2.7.7.6 Q9KWU7 26349032 EIKRFGRIREVIPLPPLTEIQVESYKKALQADVPPEKRENVGIQAAFKETFPIEEGGLVLDFLEYRIGDPPFSQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHLPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEASGVVTMKVNKRKFPLVLLLRVLGYDQETLVRELSAYGDLVQGLLDEAVLAMRPEEAMVRLFTLLRPGDPPKKDKALAYLFGLLADPKRYDLGEAGRYKAEEKLGVGLSGRTLVRFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMADQFRVGLARLARGVRERMVMGSPDTLTPAKLVNSRPLEAALREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDALGFIRTPYRRVKNGVVTEEVVYMTASEEDRYTIAQANTPLEGDRIATDRVVARRRGEPVIVAPEEVEFMDVSPKQVFSLNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVVKVDGTRIAVRYEDGRLVEHPLRRYARSNQGTAFDQRPRVRVGQRVKKGDLLADGPASEEGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGIVRIGAEVKPGDILVGRTSFKGEQEPSPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVGRLRLRRGDPGVELKPGVREVVRVFVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPVFDGATEPEIKELLAEAFNLYFGKRQGEGFGVDKREKEVLARAEKLGLVSPGKSPEEQLKELFDLGKVVLYDGRTGEPFEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIEGRNAAYQAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 4xln C 4.00 BS02 NUC P 1 R134 R376 R383 R388 F394 E421 K1004 G1023 K1024 Q1030 R1031 G1033 M1035 R128 R370 R377 R382 F388 E415 K998 G1017 K1018 Q1024 R1025 G1027 M1029 2.7.7.6 Q9KWU7 26349032 EIKRFGRIREVIPLPPLTEIQVESYKKALQADVPPEKRENVGIQAAFKETFPIEEGGLVLDFLEYRIGDPPFSQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHLPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEASGVVTMKVNKRKFPLVLLLRVLGYDQETLVRELSAYGDLVQGLLDEAVLAMRPEEAMVRLFTLLRPGDPPKKDKALAYLFGLLADPKRYDLGEAGRYKAEEKLGVGLSGRTLVRFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMADQFRVGLARLARGVRERMVMGSPDTLTPAKLVNSRPLEAALREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDALGFIRTPYRRVKNGVVTEEVVYMTASEEDRYTIAQANTPLEGDRIATDRVVARRRGEPVIVAPEEVEFMDVSPKQVFSLNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVVKVDGTRIAVRYEDGRLVEHPLRRYARSNQGTAFDQRPRVRVGQRVKKGDLLADGPASEEGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGIVRIGAEVKPGDILVGRTSFKGEQEPSPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVGRLRLRRGDPGVELKPGVREVVRVFVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPVFDGATEPEIKELLAEAFNLYFGKRQGEGFGVDKREKEVLARAEKLGLVSPGKSPEEQLKELFDLGKVVLYDGRTGEPFEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIEGRNAAYQAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 4xln C 4.00 BS03 NUC Q 1 R409 L413 R420 P444 I452 Q567 K838 K846 H999 R403 L407 R414 P438 I446 Q561 K832 K840 H993 2.7.7.6 Q9KWU7 26349032 EIKRFGRIREVIPLPPLTEIQVESYKKALQADVPPEKRENVGIQAAFKETFPIEEGGLVLDFLEYRIGDPPFSQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHLPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEASGVVTMKVNKRKFPLVLLLRVLGYDQETLVRELSAYGDLVQGLLDEAVLAMRPEEAMVRLFTLLRPGDPPKKDKALAYLFGLLADPKRYDLGEAGRYKAEEKLGVGLSGRTLVRFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMADQFRVGLARLARGVRERMVMGSPDTLTPAKLVNSRPLEAALREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDALGFIRTPYRRVKNGVVTEEVVYMTASEEDRYTIAQANTPLEGDRIATDRVVARRRGEPVIVAPEEVEFMDVSPKQVFSLNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVVKVDGTRIAVRYEDGRLVEHPLRRYARSNQGTAFDQRPRVRVGQRVKKGDLLADGPASEEGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGIVRIGAEVKPGDILVGRTSFKGEQEPSPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVGRLRLRRGDPGVELKPGVREVVRVFVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPVFDGATEPEIKELLAEAFNLYFGKRQGEGFGVDKREKEVLARAEKLGLVSPGKSPEEQLKELFDLGKVVLYDGRTGEPFEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIEGRNAAYQAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 4xln D 4.00 BS01 NUC O 1 Y34 R1266 R1267 K1426 Y33 R1251 R1252 K1411 2.7.7.6 Q9KWU6 26349032 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLRKERAALRIPLSAWVEKEAYRPGEVLAELSEPYLFRAEESGVVELKDLAEGHLIYLRQEEEVVARYFLPAGMTPLVVEGEIVEVGQPLAEGKGLLRLPRHMTAKEVEAEEEGDSVHLTLFLEWTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xln D 4.00 BS02 NUC P 1 R534 R586 K610 R615 R622 R628 P706 A1089 G1092 Y1093 Q1441 N1442 T1444 R533 R585 K609 R614 R621 R627 P705 A1088 G1091 Y1092 Q1426 N1427 T1429 2.7.7.6 Q9KWU6 26349032 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLRKERAALRIPLSAWVEKEAYRPGEVLAELSEPYLFRAEESGVVELKDLAEGHLIYLRQEEEVVARYFLPAGMTPLVVEGEIVEVGQPLAEGKGLLRLPRHMTAKEVEAEEEGDSVHLTLFLEWTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xln D 4.00 BS04 ZN D 1 C1112 C1194 C1201 C1204 C1111 C1193 C1200 C1203 2.7.7.6 Q9KWU6 26349032 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLRKERAALRIPLSAWVEKEAYRPGEVLAELSEPYLFRAEESGVVELKDLAEGHLIYLRQEEEVVARYFLPAGMTPLVVEGEIVEVGQPLAEGKGLLRLPRHMTAKEVEAEEEGDSVHLTLFLEWTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xln F 4.00 BS01 NUC O 1 V96 R97 L100 H101 G104 L108 A205 N206 R208 L209 S212 K215 F224 R237 K241 F242 E243 R246 F248 K249 S251 T252 Y253 T255 W256 W257 R259 Q260 R264 R274 P276 V277 H278 R379 V407 T408 R409 R411 Q414 V5 R6 L9 H10 G13 L17 A114 N115 R117 L118 S121 K124 F133 R146 K150 F151 E152 R155 F157 K158 S160 T161 Y162 T164 W165 W166 R168 Q169 R173 R183 P185 V186 H187 R288 V316 T317 R318 R320 Q323 Q9EZJ8 26349032 TSDPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xln F 4.00 BS02 NUC P 1 R220 R259 Q260 N263 R271 E281 I283 N284 S287 R288 R291 A326 I336 E339 F347 R387 T397 L398 R409 E410 R413 R129 R168 Q169 N172 R180 E190 I192 N193 S196 R197 R200 A235 I245 E248 F256 R296 T306 L307 R318 E319 R322 Q9EZJ8 26349032 TSDPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xln F 4.00 BS03 NUC Q 1 D338 E339 D247 E248 Q9EZJ8 26349032 TSDPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xln I 4.00 BS02 NUC S 1 R134 F394 E421 K1004 G1023 K1024 Q1030 R1031 G1033 M1035 R128 F388 E415 K998 G1017 K1018 Q1024 R1025 G1027 M1029 2.7.7.6 Q9KWU7 26349032 EIKRFGRIREVIPLPPLTEIQVESYKKALQADVPPEKRENVGIQAAFKETFPIEEGGLVLDFLEYRIGDPPFSQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHLPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEASGVVTMKVNKRKFPLVLLLRVLGYDQETLVRELSAYGDLVQGLLDEAVLAMRPEEAMVRLFTLLRPGDPPKKDKALAYLFGLLADPKRYDLGEAGRYKAEEKLGVGLSGRTLVRFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMADQFRVGLARLARGVRERMVMGSPDTLTPAKLVNSRPLEAALREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDALGFIRTPYRRVKNGVVTEEVVYMTASEEDRYTIAQANTPLEGDRIATDRVVARRRGEPVIVAPEEVEFMDVSPKQVFSLNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVVKVDGTRIAVRYEDGRLVEHPLRRYARSNQGTAFDQRPRVRVGQRVKKGDLLADGPASEEGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGIVRIGAEVKPGDILVGRTSFKGEQEPSPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVGRLRLRRGDPGVELKPGVREVVRVFVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPVFDGATEPEIKELLAEAFNLYFGKRQGEGFGVDKREKEVLARAEKLGLVSPGKSPEEQLKELFDLGKVVLYDGRTGEPFEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIEGRNAAYQAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 4xln I 4.00 BS03 NUC T 1 R409 L413 R420 P444 N448 I452 Q567 K838 K846 H999 R403 L407 R414 P438 N442 I446 Q561 K832 K840 H993 2.7.7.6 Q9KWU7 26349032 EIKRFGRIREVIPLPPLTEIQVESYKKALQADVPPEKRENVGIQAAFKETFPIEEGGLVLDFLEYRIGDPPFSQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHLPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEASGVVTMKVNKRKFPLVLLLRVLGYDQETLVRELSAYGDLVQGLLDEAVLAMRPEEAMVRLFTLLRPGDPPKKDKALAYLFGLLADPKRYDLGEAGRYKAEEKLGVGLSGRTLVRFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMADQFRVGLARLARGVRERMVMGSPDTLTPAKLVNSRPLEAALREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDALGFIRTPYRRVKNGVVTEEVVYMTASEEDRYTIAQANTPLEGDRIATDRVVARRRGEPVIVAPEEVEFMDVSPKQVFSLNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVVKVDGTRIAVRYEDGRLVEHPLRRYARSNQGTAFDQRPRVRVGQRVKKGDLLADGPASEEGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGIVRIGAEVKPGDILVGRTSFKGEQEPSPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVGRLRLRRGDPGVELKPGVREVVRVFVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPVFDGATEPEIKELLAEAFNLYFGKRQGEGFGVDKREKEVLARAEKLGLVSPGKSPEEQLKELFDLGKVVLYDGRTGEPFEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIEGRNAAYQAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 4xln J 4.00 BS01 NUC R 1 Y34 R1266 R1267 K1426 Y33 R1128 R1129 K1288 2.7.7.6 Q9KWU6 26349032 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xln J 4.00 BS02 NUC S 1 R586 K610 R615 R622 R628 P706 A1089 G1092 Y1093 Q1441 N1442 T1444 R462 K486 R491 R498 R504 P582 A965 G968 Y969 Q1303 N1304 T1306 2.7.7.6 Q9KWU6 26349032 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xln J 4.00 BS03 NUC T 1 R704 D741 D743 R580 D617 D619 2.7.7.6 Q9KWU6 26349032 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xln L 4.00 BS02 NUC S 1 R220 R259 Q260 N263 E281 N284 R288 I336 E339 F347 R387 T397 L398 R409 E410 R413 R129 R168 Q169 N172 E190 N193 R197 I245 E248 F256 R296 T306 L307 R318 E319 R322 Q9EZJ8 26349032 TSDPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xlp F 4.00 BS01 NUC O 1 L108 A205 N206 L209 R237 K241 F242 E243 R246 F248 K249 S251 T252 Y253 T255 W256 W257 Q260 R264 R274 P276 V277 H278 V407 T408 E410 R411 Q414 L15 A112 N113 L116 R144 K148 F149 E150 R153 F155 K156 S158 T159 Y160 T162 W163 W164 Q167 R171 R181 P183 V184 H185 V314 T315 E317 R318 Q321 Q9EZJ8 26349032 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xlp F 4.00 BS02 NUC P 1 T397 L398 R409 E410 R413 T304 L305 R316 E317 R320 Q9EZJ8 26349032 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xlq D 4.60 BS01 ZN D 1 C1112 R1189 C1194 C1201 C1204 C1111 R1188 C1193 C1200 C1203 2.7.7.6 Q9KWU6 26349032 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLRKERAALRIPLSAWVEKEAYRPGEVLAELSEPYLFRAEESGVVELKDLAEGHLIYLRQEEEVVARYFLPAGMTPLVVEGEIVEVGQPLAEGKGLLRLPRHMTAKEVEAEEEGDSVHLTLFLEWTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xlq F 4.60 BS01 NUC O 1 L109 A205 N206 R208 L209 R237 K241 F242 E243 R246 R247 F248 K249 S251 T252 Y253 T255 W256 W257 Q260 R264 R274 P276 V277 H278 R379 V407 T408 R409 E410 R411 Q414 L16 A112 N113 R115 L116 R144 K148 F149 E150 R153 R154 F155 K156 S158 T159 Y160 T162 W163 W164 Q167 R171 R181 P183 V184 H185 R286 V314 T315 R316 E317 R318 Q321 Q9EZJ8 26349032 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xlq F 4.60 BS02 NUC P 1 R220 Q260 N263 E281 N284 R387 T397 L398 E399 R409 E410 R413 R127 Q167 N170 E188 N191 R294 T304 L305 E306 R316 E317 R320 Q9EZJ8 26349032 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xlq L 4.60 BS02 NUC S 1 K216 R220 W256 Q260 N263 E281 N284 T397 L398 E399 R409 E410 R413 K123 R127 W163 Q167 N170 E188 N191 T304 L305 E306 R316 E317 R320 Q9EZJ8 26349032 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xlr C 4.30 BS01 NUC O 1 R142 I163 P166 K167 G169 P170 W171 N187 R243 D246 P247 Y256 L260 R266 D326 R331 L418 E421 R422 V427 R141 I162 P165 K166 G168 P169 W170 N186 R242 D245 P246 Y255 L259 R265 D325 R330 L417 E420 R421 V426 2.7.7.6 Q9KWU7 26349034 EIKRFGRIREVIPLPPLTEIQVESYKKALQADVPPEKRENVGIQAAFKETFPIEEGDKGKGGLVLDFLEYRIGDPPFSQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHLPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEASGVVTMKVNKRKFPLVLLLRVLGYDQETLVRELSAYGDLVQGLLDEAVLAMRPEEAMVRLFTLLRPGDPPKKDKALAYLFGLLADPKRYDLGEAGRYKAEEKLGVGLSGRTLVRFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMADQFRVGLARLARGVRERMVMGSPDTLTPAKLVNSRPLEAALREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDALGFIRTPYRRVKNGVVTEEVVYMTASEEDRYTIAQANTPLEGDRIATDRVVARRRGEPVIVAPEEVEFMDVSPKQVFSLNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVVKVDGTRIAVRYEDGRLVEHPLRRYARSNQGTAFDQRPRVRVGQRVKKGDLLADGPASEEGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGIVRIGAEVKPGDILVGRTSFKGEQEPSPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVGRLRLRRGDPGVELKPGVREVVRVFVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPVFDGATEPEIKELLAEAFNLYFGKRQGEGFGVDKREKEVLARAEKLGLVSPGKSPEEQLKELFDLGKVVLYDGRTGEPFEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIEGRNAAYQAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 4xlr C 4.30 BS02 NUC P 1 R383 R388 F394 P817 K1004 G1023 K1024 Q1030 R1031 G1033 M1035 R382 R387 F393 P816 K1003 G1022 K1023 Q1029 R1030 G1032 M1034 2.7.7.6 Q9KWU7 26349034 EIKRFGRIREVIPLPPLTEIQVESYKKALQADVPPEKRENVGIQAAFKETFPIEEGDKGKGGLVLDFLEYRIGDPPFSQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHLPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEASGVVTMKVNKRKFPLVLLLRVLGYDQETLVRELSAYGDLVQGLLDEAVLAMRPEEAMVRLFTLLRPGDPPKKDKALAYLFGLLADPKRYDLGEAGRYKAEEKLGVGLSGRTLVRFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMADQFRVGLARLARGVRERMVMGSPDTLTPAKLVNSRPLEAALREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDALGFIRTPYRRVKNGVVTEEVVYMTASEEDRYTIAQANTPLEGDRIATDRVVARRRGEPVIVAPEEVEFMDVSPKQVFSLNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVVKVDGTRIAVRYEDGRLVEHPLRRYARSNQGTAFDQRPRVRVGQRVKKGDLLADGPASEEGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGIVRIGAEVKPGDILVGRTSFKGEQEPSPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVGRLRLRRGDPGVELKPGVREVVRVFVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPVFDGATEPEIKELLAEAFNLYFGKRQGEGFGVDKREKEVLARAEKLGLVSPGKSPEEQLKELFDLGKVVLYDGRTGEPFEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIEGRNAAYQAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 4xlr C 4.30 BS03 NUC Q 1 Q390 R409 L413 R420 P444 E445 N563 Q567 K838 K846 H999 Q389 R408 L412 R419 P443 E444 N562 Q566 K837 K845 H998 2.7.7.6 Q9KWU7 26349034 EIKRFGRIREVIPLPPLTEIQVESYKKALQADVPPEKRENVGIQAAFKETFPIEEGDKGKGGLVLDFLEYRIGDPPFSQDECREKDLTYQAPLYARLQLIHKDTGLIKEDEVFLGHLPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGRYIASIIPLPKRGPWIDLEVEASGVVTMKVNKRKFPLVLLLRVLGYDQETLVRELSAYGDLVQGLLDEAVLAMRPEEAMVRLFTLLRPGDPPKKDKALAYLFGLLADPKRYDLGEAGRYKAEEKLGVGLSGRTLVRFEDGEFKDEVFLPTLRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMADQFRVGLARLARGVRERMVMGSPDTLTPAKLVNSRPLEAALREFFSRSQLSQFKDETNPLSSLRHKRRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYARVDALGFIRTPYRRVKNGVVTEEVVYMTASEEDRYTIAQANTPLEGDRIATDRVVARRRGEPVIVAPEEVEFMDVSPKQVFSLNTNLIPFLEHDDANRALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVVKVDGTRIAVRYEDGRLVEHPLRRYARSNQGTAFDQRPRVRVGQRVKKGDLLADGPASEEGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEIEARDTKLGPERITRDIPHLSEAALRDLDEEGIVRIGAEVKPGDILVGRTSFKGEQEPSPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVGRLRLRRGDPGVELKPGVREVVRVFVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPVFDGATEPEIKELLAEAFNLYFGKRQGEGFGVDKREKEVLARAEKLGLVSPGKSPEEQLKELFDLGKVVLYDGRTGEPFEGPIVVGQMFIMKLYHMVEDKMHARSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTIKSDDIEGRNAAYQAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVDIFEGLASK 4xlr D 4.30 BS01 NUC O 1 Y34 V108 S119 A120 R1266 R1267 K1426 Y33 V107 S118 A119 R1251 R1252 K1411 2.7.7.6 Q9KWU6 26349034 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLRKERAALRIPLSAWVEKEAYRPGEVLAELSEPYLFRAEESGVVELKDLAEGHLIYLRQEEEVVARYFLPAGMTPLVVEGEIVEVGQPLAEGKGLLRLPRHMTAKEVEAEEEGDSVHLTLFLEWTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xlr D 4.30 BS02 NUC P 1 R534 R586 K610 R615 R622 R628 A705 P706 T1088 A1089 G1092 Y1093 Q1441 N1442 R533 R585 K609 R614 R621 R627 A704 P705 T1087 A1088 G1091 Y1092 Q1426 N1427 2.7.7.6 Q9KWU6 26349034 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLRKERAALRIPLSAWVEKEAYRPGEVLAELSEPYLFRAEESGVVELKDLAEGHLIYLRQEEEVVARYFLPAGMTPLVVEGEIVEVGQPLAEGKGLLRLPRHMTAKEVEAEEEGDSVHLTLFLEWTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xlr D 4.30 BS03 NUC Q 1 R704 D741 G742 D743 Q744 R703 D740 G741 D742 Q743 2.7.7.6 Q9KWU6 26349034 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLRKERAALRIPLSAWVEKEAYRPGEVLAELSEPYLFRAEESGVVELKDLAEGHLIYLRQEEEVVARYFLPAGMTPLVVEGEIVEVGQPLAEGKGLLRLPRHMTAKEVEAEEEGDSVHLTLFLEWTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xlr D 4.30 BS04 ZN D 1 C1112 R1189 C1194 T1196 C1201 C1204 C1111 R1188 C1193 T1195 C1200 C1203 2.7.7.6 Q9KWU6 26349034 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLRKERAALRIPLSAWVEKEAYRPGEVLAELSEPYLFRAEESGVVELKDLAEGHLIYLRQEEEVVARYFLPAGMTPLVVEGEIVEVGQPLAEGKGLLRLPRHMTAKEVEAEEEGDSVHLTLFLEWTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xlr F 4.30 BS02 NUC P 1 K216 Y217 T218 R220 Q260 N263 E281 N284 S287 R288 R291 Q327 I336 D338 E339 S342 F347 R387 T397 L398 E399 R409 E410 R413 K123 Y124 T125 R127 Q167 N170 E188 N191 S194 R195 R198 Q234 I243 D245 E246 S249 F254 R294 T304 L305 E306 R316 E317 R320 Q9EZJ8 26349034 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xlr J 4.30 BS01 NUC R 1 Y34 V108 S119 A120 R1266 R1267 K1426 Y33 V107 S118 A119 R1128 R1129 K1288 2.7.7.6 Q9KWU6 26349034 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xlr J 4.30 BS02 NUC S 1 R534 R586 K610 R615 R622 R628 A705 P706 T1088 A1089 G1092 Y1093 Q1441 N1442 T1443 R410 R462 K486 R491 R498 R504 A581 P582 T964 A965 G968 Y969 Q1303 N1304 T1305 2.7.7.6 Q9KWU6 26349034 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xlr J 4.30 BS03 NUC T 1 R704 D741 G742 D743 R580 D617 G618 D619 2.7.7.6 Q9KWU6 26349034 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xlr J 4.30 BS04 ZN J 1 C1112 R1189 C1194 T1196 C1201 C1204 C988 R1065 C1070 T1072 C1077 C1080 2.7.7.6 Q9KWU6 26349034 KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTRSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFNKYIVLDPKGAVLDGVPVEKRQLLTDEEYRELRYGKQETYPLPAGVDALVKDGEEVVKGQELAPGVVSRMDGVALYRFPRRVRVDYLTEPKDYKVAPHMNVIVPEGAKVQAGEKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVTTGDRVAPGDVLADGGKVKSEIYGRVEVDLVRNVVRVVESYDIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEEALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQDVVTVRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQRYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREADCGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLEEGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGVVAAESIGEPGTQLTMTQGLPRVIELFEARRPKAKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIEIVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKVPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQRTLKAIEEARKEAVEA 4xlr L 4.30 BS01 NUC R 1 V96 R97 L100 H101 I103 G104 L109 E114 A205 N206 R208 L209 S212 K215 F224 R237 K241 F242 E243 R246 F248 K249 S251 T252 Y253 T255 W256 W257 Q260 R264 R274 P276 V277 H278 R379 G406 V407 T408 R409 R411 V3 R4 L7 H8 I10 G11 L16 E21 A112 N113 R115 L116 S119 K122 F131 R144 K148 F149 E150 R153 F155 K156 S158 T159 Y160 T162 W163 W164 Q167 R171 R181 P183 V184 H185 R286 G313 V314 T315 R316 R318 Q9EZJ8 26349034 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xlr M 4.30 BS01 NUC O 1 Q85 W86 R91 Q83 W84 R89 H9ZP94 26349034 EFRPGDKVVLPPYGVGVVAGIAQRSVSGVSRAYYQVDFPGSRSKAYVPVEAPHSVGLRKALAPEEVPVILDLLKNGRMPLPKQWAARHRKTSEILADGNPYRIAQMAGQLRAWEVERGLPDLDRQALRRAIHLLAEEVAQSLEITVQEAKRLFEEAWG 4xlr M 4.30 BS02 NUC P 1 W86 P122 D123 L124 W84 P120 D121 L122 H9ZP94 26349034 EFRPGDKVVLPPYGVGVVAGIAQRSVSGVSRAYYQVDFPGSRSKAYVPVEAPHSVGLRKALAPEEVPVILDLLKNGRMPLPKQWAARHRKTSEILADGNPYRIAQMAGQLRAWEVERGLPDLDRQALRRAIHLLAEEVAQSLEITVQEAKRLFEEAWG 4xlr N 4.30 BS01 NUC R 1 Q85 W86 A87 R91 Q83 W84 A85 R89 H9ZP94 26349034 EFRPGDKVVLPPYGVGVVAGIAQRSVSGVSRAYYQVDFPGSRSKAYVPVEAPHSVGLRKALAPEEVPVILDLLKNGRMPLPKQWAARHRKTSEILADGNPYRIAQMAGQLRAWEVERGLPDLDRQALRRAIHLLAEEVAQSLEITVQEAKRLFEEAWG 4xls F 4.01 BS02 NUC P 1 R387 T397 L398 E399 R409 E410 R413 R294 T304 L305 E306 R316 E317 R320 Q9EZJ8 26349034 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xls L 4.01 BS02 NUC S 1 E281 R387 T397 L398 E399 R409 E410 R413 E188 R294 T304 L305 E306 R316 E317 R320 Q9EZJ8 26349034 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE 4xls M 4.01 BS01 NUC O 1 Q85 W86 Q83 W84 H9ZP94 26349034 EFRPGDKVVLPPYGVGVVAGIAQRSVSGVSRAYYQVDFPGSRSKAYVPVEAPHSVGLRKALAPEEVPVILDLLKNGRMPLPKQWAARHRKTSEILADGNPYRIAQMAGQLRAWEVERGLPDLDRQALRRAIHLLAEEVAQSLEITVQEAKRLFEEAWGEELN 4xls M 4.01 BS02 NUC P 1 P122 D123 L124 P120 D121 L122 H9ZP94 26349034 EFRPGDKVVLPPYGVGVVAGIAQRSVSGVSRAYYQVDFPGSRSKAYVPVEAPHSVGLRKALAPEEVPVILDLLKNGRMPLPKQWAARHRKTSEILADGNPYRIAQMAGQLRAWEVERGLPDLDRQALRRAIHLLAEEVAQSLEITVQEAKRLFEEAWGEELN 4xzj A 1.80 BS01 NAD A 1 S68 Y72 N76 R80 R117 G118 T119 W120 S142 T143 S144 A150 F153 P158 L164 E189 E191 L232 Y233 S50 Y54 N58 R62 R99 G100 T101 W102 S124 T125 S126 A132 F135 P140 L146 E171 E173 L214 Y215 2.4.2.31 26352925 GPFDAIKQPNRSEEEVTQLAEDFKDWSKASNGWRYSFITANEKEAVEDFSISGYQTANDYLRATDTSTWGVAGADARQYIRTVKSALNKLPKYKGTAYRGTWVKLSLLNKLEEGDVLVEPAFTSTSTLPEVAKRFSVVHPNSPQRLKRVLFEVKINQGGHTIAGLSEYSKEAEVLFAPNAHFRITQIERTSNHTYIGVETVKASAVKNTQKYNLYSGEEVEA 4y08 A 1.34 BS04 OXY A 1 E62 H65 E107 V110 Q141 E58 H61 E103 V106 Q137 1.16.3.1 P02794 26327381 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 4y08 A 1.34 BS05 OXY A 2 E62 H65 E107 Q141 A144 E58 H61 E103 Q137 A140 1.16.3.1 P02794 26327381 TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLG 4y0k A 2.20 BS01 NAP A 1 Y68 W72 A186 T190 W212 G213 G216 G217 L218 V237 S238 R242 R257 H305 S306 D309 T310 C327 T330 T331 H353 V354 H397 Y63 W67 A181 T185 W207 G208 G211 G212 L213 V232 S233 R237 R252 H300 S301 D304 T305 C322 T325 T326 H348 V349 H392 M1SQA1 26356484 TKDLYELGDAPPLGTAPKQMYASLIRQERYGRPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNNVWAALGEPLDVIAARQKQGATEDFHIGGSDLSGIVWAVGDGVRLKPGAEVVVLACRWDESAQDIRLGADPVTSSTQRVWGYEENYGSFAQFAVVDEYMCHPKPQRLSWAAASCYMATAATAYRQLFGWEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGGIPVAVVSSEERGEFCMRLGAKGWIDRREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFWEVLGERRAPRIVLEHSGADTIPTSIYMADNAGMVVICGGTTGYNGDVDLRFLWMRQKRLQGSHVASAREAREITRLIDQGAIDPCLSRTFGFEEIGLAHQLIHDNQHPSGNMAVLVNATE 4y19 A 2.50 BS01 III C 1 Q9 E11 F24 A52 S53 F54 G58 N62 V65 D66 N69 M73 Q7 E9 F22 A50 S51 F52 G56 N60 V63 D64 N67 M71 P01903 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4y19 B 2.50 BS01 III C 1 V11 H13 F26 Y30 Y37 Y47 D57 Y60 W61 L67 K71 Y78 H81 N82 V85 V12 H14 F27 Y31 Y38 Y48 D58 Y61 W62 L68 K72 Y79 H82 N83 V86 P13760 SGDTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPANLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRAT 4y19 E 2.50 BS01 III C 1 E63 G64 K68 E51 G52 K56 AGVTQTPKFRVLKTGQSMTLLCAQDMNHEYMYWYRQDPGMGLRLIHYSVGEGTTAKGEVPDGYNVSRLKKQNFLLGLESAAPSQTSVYFCASRPRRDNEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFFPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 4y1a A 4.00 BS01 III C 1 Q9 E11 F22 F32 R50 F51 A52 S53 G58 N62 N69 M73 Q6 E8 F19 F29 R47 F48 A49 S50 G55 N59 N66 M70 P01903 EHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4y1a B 4.00 BS01 III C 1 H13 Y30 Y37 Y47 D57 Y60 W61 L67 K71 Y78 H81 N82 V85 H14 Y31 Y38 Y48 D58 Y61 W62 L68 K72 Y79 H82 N83 V86 P13760 SGDTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPANLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRAT 4y1b A 1.50 BS01 NAP A 1 Y64 A182 T183 T186 W208 G209 G212 G213 L214 V233 S234 R238 R253 H301 S302 D305 T306 C323 T326 T327 H349 A350 H393 Y63 A181 T182 T185 W207 G208 G211 G212 L213 V232 S233 R237 R252 H300 S301 D304 T305 C322 T325 T326 H348 A349 H392 M1SQA1 26356484 TKDLYELGDAPPLGTAPKQMYASLIRQERYGRPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNNVWAALGEPLDVIAARQKQGATEDFHIGGSDLSGIVWAVGDGVRLKPGAEVVVLACRWDESAQDIRLGADPVTSSTQRVWGYEENYGSFAQFAVVDEYMCHPKPQRLSWAAASCYMATAATAYRQLFGWEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGGIPVAVVSSEERGEFCMRLGAKGWIDRREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFWEVLGERRAPRIVLEHSGADTIPTSIYMADNAGMVVICGGTTGYNGDVDLRFLWMRQKRLQGSHAASAREAREITRLIDQGAIDPCLSRTFGFEEIGLAHQLIHDNQHPSGNMAVLVNAT 4y2w A 2.70 BS01 PO4 A 1 Y44 N208 A209 R224 G226 I227 Y44 N208 A209 R224 G226 I227 5.1.1.1 Q8RAK6 26218070 VKFDGVRPTRVEVYLDAITHNFREIKKIVGKNVKIMAVIKGDAYGHGASYVAKFLEKEGVDYFGVATTEEALELREKGIKTPILIFGYTPPTQLRQIVKHDLTQTVYDIKYAKELEKESLKQNKRAKVHIKIDTGLGRIGYIDFDLAQKEILEMANMRGLILEGIYSHFAAASEDDRDYCKEQFDKFMNLISSLEKKRLKIPLKHIANAAAILNLNYSHLDMVRPGIILFGAYPSKRVERKVELRETLRFTTRVVHLKDVPAGFFIGYGKSFVTKRKSVIATIPVGYADGLDRRLSNNYKLLLKGKYVPIVGRVCMDQCMIDVTDVEGVEIGDEVVIIGTQNNETVSVESMADKIETIPQEVFSRISRRVPRVYFYDGIKIGEVNYLK 4y2w A 2.70 BS02 ALA A 1 Y268 Y287 C315 M316 Y268 Y287 C315 M316 5.1.1.1 Q8RAK6 26218070 VKFDGVRPTRVEVYLDAITHNFREIKKIVGKNVKIMAVIKGDAYGHGASYVAKFLEKEGVDYFGVATTEEALELREKGIKTPILIFGYTPPTQLRQIVKHDLTQTVYDIKYAKELEKESLKQNKRAKVHIKIDTGLGRIGYIDFDLAQKEILEMANMRGLILEGIYSHFAAASEDDRDYCKEQFDKFMNLISSLEKKRLKIPLKHIANAAAILNLNYSHLDMVRPGIILFGAYPSKRVERKVELRETLRFTTRVVHLKDVPAGFFIGYGKSFVTKRKSVIATIPVGYADGLDRRLSNNYKLLLKGKYVPIVGRVCMDQCMIDVTDVEGVEIGDEVVIIGTQNNETVSVESMADKIETIPQEVFSRISRRVPRVYFYDGIKIGEVNYLK 4y2w A 2.70 BS03 ALA B 1 K40 Q360 K40 Q360 5.1.1.1 Q8RAK6 26218070 VKFDGVRPTRVEVYLDAITHNFREIKKIVGKNVKIMAVIKGDAYGHGASYVAKFLEKEGVDYFGVATTEEALELREKGIKTPILIFGYTPPTQLRQIVKHDLTQTVYDIKYAKELEKESLKQNKRAKVHIKIDTGLGRIGYIDFDLAQKEILEMANMRGLILEGIYSHFAAASEDDRDYCKEQFDKFMNLISSLEKKRLKIPLKHIANAAAILNLNYSHLDMVRPGIILFGAYPSKRVERKVELRETLRFTTRVVHLKDVPAGFFIGYGKSFVTKRKSVIATIPVGYADGLDRRLSNNYKLLLKGKYVPIVGRVCMDQCMIDVTDVEGVEIGDEVVIIGTQNNETVSVESMADKIETIPQEVFSRISRRVPRVYFYDGIKIGEVNYLK 4y2w B 2.70 BS01 PO4 B 1 N208 A209 G226 I227 N208 A209 G226 I227 5.1.1.1 Q8RAK6 26218070 VKFDGVRPTRVEVYLDAITHNFREIKKIVGKNVKIMAVIKGDAYGHGASYVAKFLEKEGVDYFGVATTEEALELREKGIKTPILIFGYTPPTQLRQIVKHDLTQTVYDIKYAKELEKESLKQNKRAKVHIKIDTGLGRIGYIDFDLAQKEILEMANMRGLILEGIYSHFAAASEDDRDYCKEQFDKFMNLISSLEKKRLKIPLKHIANAAAILNLNYSHLDMVRPGIILFGAYPSKRVERKVELRETLRFTTRVVHLKDVPAGFFIGYGKSFVTKRKSVIATIPVGYADGLDRRLSNNYKLLLKGKYVPIVGRVCMDQCMIDVTDVEGVEIGDEVVIIGTQNNETVSVESMADKIETIPQEVFSRISRRVPRVYFYDGIKIGEVNYLK 4y2w B 2.70 BS02 ALA B 1 Y268 Y287 Y268 Y287 5.1.1.1 Q8RAK6 26218070 VKFDGVRPTRVEVYLDAITHNFREIKKIVGKNVKIMAVIKGDAYGHGASYVAKFLEKEGVDYFGVATTEEALELREKGIKTPILIFGYTPPTQLRQIVKHDLTQTVYDIKYAKELEKESLKQNKRAKVHIKIDTGLGRIGYIDFDLAQKEILEMANMRGLILEGIYSHFAAASEDDRDYCKEQFDKFMNLISSLEKKRLKIPLKHIANAAAILNLNYSHLDMVRPGIILFGAYPSKRVERKVELRETLRFTTRVVHLKDVPAGFFIGYGKSFVTKRKSVIATIPVGYADGLDRRLSNNYKLLLKGKYVPIVGRVCMDQCMIDVTDVEGVEIGDEVVIIGTQNNETVSVESMADKIETIPQEVFSRISRRVPRVYFYDGIKIGEVNYLK 4y59 A 1.22 BS01 T21 A 1 N23 S27 Y43 S45 V47 G48 N49 A50 W79 A86 S88 W92 W108 D128 N9 S13 Y29 S31 V33 G34 N35 A36 W65 A72 S74 W78 W94 D114 P22629 26261872 AGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKP 4y59 B 1.22 BS01 T21 B 1 N23 S27 Y43 W79 A86 S88 W92 W108 D128 N9 S13 Y29 W65 A72 S74 W78 W94 D114 P22629 26261872 AGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKP 4y5d A 1.20 BS01 MT6 A 1 N23 S27 Y43 S45 V47 N49 A50 W79 A86 S88 W92 W108 L110 S112 D128 N9 S13 Y29 S31 V33 N35 A36 W65 A72 S74 W78 W94 L96 S98 D114 P22629 26261872 AGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKPS 4y5d B 1.20 BS01 MT6 B 1 N23 S27 Y43 W79 A86 S88 T90 W92 W108 D128 N9 S13 Y29 W65 A72 S74 T76 W78 W94 D114 P22629 26261872 AGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKPS 4y5d D 1.20 BS01 MT6 D 1 N23 S27 Y43 S45 W79 A86 S88 W92 W108 D128 N9 S13 Y29 S31 W65 A72 S74 W78 W94 D114 P22629 26261872 AGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKPS 4y7e A 1.50 BS01 BMA A 1 W80 Y81 G307 T309 W30 Y31 G257 T259 3.2.1.4 F5HR99 26257335 VTGLHVQGGRLLEGNGNDFVMRGVNHAHTWYPGQTRSLADIKALGANTVRVVLSDGHRWTRNGPADVAAVIDRCKANRLICVLEVHDTTGYGEEPAAGTLDHAADYWISLMDVLAGQEDYVIVNIGNEPWGNTDPAGWTAPTIAAVKKLRAAGLAHTLMIDAPNWGQDWQGVMRADARSVYEADPTGNLLFSIHMYSVFDTAAEIDDYLEAFVDAGLPLVIGAFGGPPDQWGDPDEDTMLAAAERLRLGYLAWSWSGNTDPVLDLAIGFDPDRLSGWGQRVFHGVHGIGETSREATVFGKLA 4y7e A 1.50 BS02 BMA A 2 W80 W109 W303 N308 T309 W30 W59 W253 N258 T259 3.2.1.4 F5HR99 26257335 VTGLHVQGGRLLEGNGNDFVMRGVNHAHTWYPGQTRSLADIKALGANTVRVVLSDGHRWTRNGPADVAAVIDRCKANRLICVLEVHDTTGYGEEPAAGTLDHAADYWISLMDVLAGQEDYVIVNIGNEPWGNTDPAGWTAPTIAAVKKLRAAGLAHTLMIDAPNWGQDWQGVMRADARSVYEADPTGNLLFSIHMYSVFDTAAEIDDYLEAFVDAGLPLVIGAFGGPPDQWGDPDEDTMLAAAERLRLGYLAWSWSGNTDPVLDLAIGFDPDRLSGWGQRVFHGVHGIGETSREATVFGKLA 4y7e A 1.50 BS03 BMA A 3 H136 E178 Y246 W303 H86 E128 Y196 W253 3.2.1.4 F5HR99 26257335 VTGLHVQGGRLLEGNGNDFVMRGVNHAHTWYPGQTRSLADIKALGANTVRVVLSDGHRWTRNGPADVAAVIDRCKANRLICVLEVHDTTGYGEEPAAGTLDHAADYWISLMDVLAGQEDYVIVNIGNEPWGNTDPAGWTAPTIAAVKKLRAAGLAHTLMIDAPNWGQDWQGVMRADARSVYEADPTGNLLFSIHMYSVFDTAAEIDDYLEAFVDAGLPLVIGAFGGPPDQWGDPDEDTMLAAAERLRLGYLAWSWSGNTDPVLDLAIGFDPDRLSGWGQRVFHGVHGIGETSREATVFGKLA 4y7e A 1.50 BS04 BMA A 4 E178 W215 Q217 Y246 E128 W165 Q167 Y196 3.2.1.4 F5HR99 26257335 VTGLHVQGGRLLEGNGNDFVMRGVNHAHTWYPGQTRSLADIKALGANTVRVVLSDGHRWTRNGPADVAAVIDRCKANRLICVLEVHDTTGYGEEPAAGTLDHAADYWISLMDVLAGQEDYVIVNIGNEPWGNTDPAGWTAPTIAAVKKLRAAGLAHTLMIDAPNWGQDWQGVMRADARSVYEADPTGNLLFSIHMYSVFDTAAEIDDYLEAFVDAGLPLVIGAFGGPPDQWGDPDEDTMLAAAERLRLGYLAWSWSGNTDPVLDLAIGFDPDRLSGWGQRVFHGVHGIGETSREATVFGKLA 4y7e A 1.50 BS05 BMA A 5 N182 W215 Q217 W219 W281 N132 W165 Q167 W169 W231 3.2.1.4 F5HR99 26257335 VTGLHVQGGRLLEGNGNDFVMRGVNHAHTWYPGQTRSLADIKALGANTVRVVLSDGHRWTRNGPADVAAVIDRCKANRLICVLEVHDTTGYGEEPAAGTLDHAADYWISLMDVLAGQEDYVIVNIGNEPWGNTDPAGWTAPTIAAVKKLRAAGLAHTLMIDAPNWGQDWQGVMRADARSVYEADPTGNLLFSIHMYSVFDTAAEIDDYLEAFVDAGLPLVIGAFGGPPDQWGDPDEDTMLAAAERLRLGYLAWSWSGNTDPVLDLAIGFDPDRLSGWGQRVFHGVHGIGETSREATVFGKLA 4y7e A 1.50 BS06 BMA A 6 N182 W219 V248 W281 N132 W169 V198 W231 3.2.1.4 F5HR99 26257335 VTGLHVQGGRLLEGNGNDFVMRGVNHAHTWYPGQTRSLADIKALGANTVRVVLSDGHRWTRNGPADVAAVIDRCKANRLICVLEVHDTTGYGEEPAAGTLDHAADYWISLMDVLAGQEDYVIVNIGNEPWGNTDPAGWTAPTIAAVKKLRAAGLAHTLMIDAPNWGQDWQGVMRADARSVYEADPTGNLLFSIHMYSVFDTAAEIDDYLEAFVDAGLPLVIGAFGGPPDQWGDPDEDTMLAAAERLRLGYLAWSWSGNTDPVLDLAIGFDPDRLSGWGQRVFHGVHGIGETSREATVFGKLA 4y7e A 1.50 BS07 BMA A 7 H136 N177 E178 Y246 W303 L313 H86 N127 E128 Y196 W253 L263 3.2.1.4 F5HR99 26257335 VTGLHVQGGRLLEGNGNDFVMRGVNHAHTWYPGQTRSLADIKALGANTVRVVLSDGHRWTRNGPADVAAVIDRCKANRLICVLEVHDTTGYGEEPAAGTLDHAADYWISLMDVLAGQEDYVIVNIGNEPWGNTDPAGWTAPTIAAVKKLRAAGLAHTLMIDAPNWGQDWQGVMRADARSVYEADPTGNLLFSIHMYSVFDTAAEIDDYLEAFVDAGLPLVIGAFGGPPDQWGDPDEDTMLAAAERLRLGYLAWSWSGNTDPVLDLAIGFDPDRLSGWGQRVFHGVHGIGETSREATVFGKLA 4y7e A 1.50 BS13 CA A 1 V248 D250 E254 V198 D200 E204 3.2.1.4 F5HR99 26257335 VTGLHVQGGRLLEGNGNDFVMRGVNHAHTWYPGQTRSLADIKALGANTVRVVLSDGHRWTRNGPADVAAVIDRCKANRLICVLEVHDTTGYGEEPAAGTLDHAADYWISLMDVLAGQEDYVIVNIGNEPWGNTDPAGWTAPTIAAVKKLRAAGLAHTLMIDAPNWGQDWQGVMRADARSVYEADPTGNLLFSIHMYSVFDTAAEIDDYLEAFVDAGLPLVIGAFGGPPDQWGDPDEDTMLAAAERLRLGYLAWSWSGNTDPVLDLAIGFDPDRLSGWGQRVFHGVHGIGETSREATVFGKLA 4y7e A 1.50 BS14 CA A 2 G276 D283 P284 E286 G226 D233 P234 E236 3.2.1.4 F5HR99 26257335 VTGLHVQGGRLLEGNGNDFVMRGVNHAHTWYPGQTRSLADIKALGANTVRVVLSDGHRWTRNGPADVAAVIDRCKANRLICVLEVHDTTGYGEEPAAGTLDHAADYWISLMDVLAGQEDYVIVNIGNEPWGNTDPAGWTAPTIAAVKKLRAAGLAHTLMIDAPNWGQDWQGVMRADARSVYEADPTGNLLFSIHMYSVFDTAAEIDDYLEAFVDAGLPLVIGAFGGPPDQWGDPDEDTMLAAAERLRLGYLAWSWSGNTDPVLDLAIGFDPDRLSGWGQRVFHGVHGIGETSREATVFGKLA 4yff A 3.07 BS01 4CV A 1 I469 V477 A488 K490 I537 T539 Q540 Y541 I542 H592 L595 D606 I25 V33 A44 K46 I86 T88 Q89 Y90 I91 H141 L144 D155 2.7.11.1 Q59H18 26355916 ILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNI 4yff B 3.07 BS01 4CV B 1 I469 A488 K490 I537 T539 Q540 Y541 I542 H592 L595 D606 I25 A44 K46 I87 T89 Q90 Y91 I92 H142 L145 D156 2.7.11.1 Q59H18 26355916 ILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNI 4yfi A 2.70 BS01 4CW A 1 I469 V477 A488 K490 T539 Q540 Y541 I542 L595 D606 I29 V37 A48 K50 T92 Q93 Y94 I95 L148 D159 2.7.11.1 Q59H18 26355916 EKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAADMDMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNI 4yfi B 2.70 BS01 4CW B 1 A488 K490 E509 T539 Q540 Y541 I542 L595 D606 A38 K40 E52 T82 Q83 Y84 I85 L138 D149 2.7.11.1 Q59H18 26355916 GLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAADMDMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELM 4yfi D 2.70 BS01 4CW D 1 A488 I522 T539 Q540 I542 L595 D606 A38 I64 T81 Q82 I84 L137 D148 2.7.11.1 Q59H18 26355916 GLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAADMDMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELM 4yu3 A 2.45 BS01 HEM A 1 Y42 F43 H45 F46 H58 K61 A65 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 H58 K61 A65 L86 H87 L91 V93 N97 F98 L101 L136 VLSPADKTNIKASWEKIGSHGGEYGAEALERTFLCFPTTKTYFPHFDLSHGSAQVKAHGKKVADALTNAVGHLDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLASHHPAEFTPAVHASLDKFLSSVSTVLTSKYR 4yu3 A 2.45 BS02 OXY A 1 F43 H58 V62 F43 H58 V62 VLSPADKTNIKASWEKIGSHGGEYGAEALERTFLCFPTTKTYFPHFDLSHGSAQVKAHGKKVADALTNAVGHLDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLASHHPAEFTPAVHASLDKFLSSVSTVLTSKYR 4yu3 B 2.45 BS01 HEM B 1 F41 F42 F45 H63 K66 S70 F71 F85 L88 H92 L96 V98 N102 L106 L141 F41 F42 F45 H63 K66 S70 F71 F85 L88 H92 L96 V98 N102 L106 L141 VHLTAEEKAHVSGLWGKVNTEEVGGEALGRLLVVYPWTQRFFETFGDLSSANAIMNNPKVKAHGKKVLSSFSDGLKNLDNLKGTFAALSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKIVAGVANALAHKYH 4yu3 B 2.45 BS02 OXY B 1 H63 V67 H92 H63 V67 H92 VHLTAEEKAHVSGLWGKVNTEEVGGEALGRLLVVYPWTQRFFETFGDLSSANAIMNNPKVKAHGKKVLSSFSDGLKNLDNLKGTFAALSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKIVAGVANALAHKYH 4yu4 A 2.80 BS02 OXY A 1 H58 V62 H58 V62 VLSPADKTNIKASWEKIGSHGGEYGAEALERTFLCFPTTKTYFPHFDLSHGSAQVKAHGKKVADALTNAVGHLDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLASHHPAEFTPAVHASLDKFLSSVSTVLTSKYR 4yu4 B 2.80 BS01 HEM B 1 T38 F41 F42 H63 S70 L88 H92 L96 V98 N102 F103 L106 L141 T38 F41 F42 H63 S70 L88 H92 L96 V98 N102 F103 L106 L141 VHLTAEEKAHVSGLWGKVNTEEVGGEALGRLLVVYPWTQRFFETFGDLSSANAIMNNPKVKAHGKKVLSSFSDGLKNLDNLKGTFAALSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKIVAGVANALAHKYH 4yu4 B 2.80 BS02 OXY B 1 H63 V67 H63 V67 VHLTAEEKAHVSGLWGKVNTEEVGGEALGRLLVVYPWTQRFFETFGDLSSANAIMNNPKVKAHGKKVLSSFSDGLKNLDNLKGTFAALSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKIVAGVANALAHKYH 4yu4 C 2.80 BS02 HEM C 1 Y42 F43 H45 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 V132 L136 Y42 F43 H45 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 V132 L136 VLSPADKTNIKASWEKIGSHGGEYGAEALERTFLCFPTTKTYFPHFDLSHGSAQVKAHGKKVADALTNAVGHLDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLASHHPAEFTPAVHASLDKFLSSVSTVLTSKYR 4yu4 D 2.80 BS02 HEM D 1 T38 F41 F42 H63 K66 V67 S70 H92 L96 V98 N102 L106 L141 T38 F41 F42 H63 K66 V67 S70 H92 L96 V98 N102 L106 L141 VHLTAEEKAHVSGLWGKVNTEEVGGEALGRLLVVYPWTQRFFETFGDLSSANAIMNNPKVKAHGKKVLSSFSDGLKNLDNLKGTFAALSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKIVAGVANALAHKYH 4yw0 A 2.05 BS01 FSI A 1 R290 I291 R309 D315 D372 D388 F396 Y553 S582 E584 R600 R662 Y695 R208 I209 R227 D233 D290 D306 F314 Y471 S500 E502 R518 R580 Y613 3.2.1.18 26370075 ETPVLEKNNVTLTGGGENVTKELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEARDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNFLNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHLIYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTWTKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPAGVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDKNFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISSNDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDNGASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYLKFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRYHHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKNL 4yw0 A 2.05 BS02 SFJ A 1 L128 F149 R151 E159 R161 R237 F243 L46 F67 R69 E77 R79 R155 F161 3.2.1.18 26370075 ETPVLEKNNVTLTGGGENVTKELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEARDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNFLNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHLIYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTWTKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPAGVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDKNFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISSNDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDNGASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYLKFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRYHHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKNL 4yw5 A 2.30 BS01 G39 A 1 R290 D315 D372 F396 Y533 Y553 S582 R600 R662 Y695 W716 R208 D233 D290 F314 Y451 Y471 S500 R518 R580 Y613 W634 3.2.1.18 26370075 ETPVLEKNNVTLTGGGENVTKELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEARDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNFLNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHLIYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTWTKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPAGVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDKNFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISSNDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDNGASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYLKFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRYHHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKNL 4yw8 A 1.55 BS03 1WD A 1 R87 Y235 K243 K244 H264 S286 D311 F333 R405 F485 R89 Y237 K245 K246 H266 S288 D313 F335 R403 F479 4.1.1.32 P07379 26322521 GSMPPQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWREPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAKGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM 4yw8 A 1.55 BS04 1WD A 2 F284 C288 G434 G435 R436 V514 N515 W516 F517 F286 C290 G432 G433 R434 V508 N509 W510 F511 4.1.1.32 P07379 26322521 GSMPPQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWREPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAKGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM 4yw8 A 1.55 BS05 MEE A 1 P285 C288 P287 C290 4.1.1.32 P07379 26322521 GSMPPQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWREPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAKGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM 4yw9 A 1.40 BS05 1WD A 1 R87 Y235 K243 K244 H264 S286 D311 F333 R405 R89 Y237 K245 K246 H266 S288 D313 F335 R404 4.1.1.32 P07379 26322521 GSMPPQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEAGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM 4ywd A 2.10 BS03 NTM A 1 R87 K243 K244 H264 S286 D311 F333 R405 R79 K235 K236 H256 S278 D303 F325 R394 4.1.1.32 P07379 26322521 LDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM 4z4c A 2.30 BS01 NUC B 1 K65 P67 R68 R97 G178 R179 F294 Y311 F312 H336 T337 Y338 I365 L522 G524 K525 T526 Y529 K533 Q545 C546 Q548 N551 T559 N562 L563 K566 K570 T599 H600 P601 P602 A603 R635 E637 S672 Q675 K709 R710 H753 I756 Q757 T759 S760 R761 Y790 R792 C793 R795 S798 Y804 R812 K44 P46 R47 R76 G151 R152 F261 Y269 F270 H294 T295 Y296 I323 L480 G482 K483 T484 Y487 K491 Q503 C504 Q506 N509 T517 N520 L521 K524 K528 T557 H558 P559 P560 A561 R593 E595 S630 Q633 K667 R668 H711 I714 Q715 T717 S718 R719 Y748 R750 C751 R753 S756 Y762 R770 3.1.26.- Q9UKV8 26359634 AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEIKRKYRVCNVTRRPASHQTFPLCTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEGRDHQALAKAVQVHQDTLRTMYFA 4z4c A 2.30 BS02 NUC D 1 D358 T361 S362 I365 K525 T556 P557 Q558 N562 K726 I756 F811 Y815 D316 T319 S320 I323 K483 T514 P515 Q516 N520 K684 I714 F769 Y773 3.1.26.- Q9UKV8 26359634 AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEIKRKYRVCNVTRRPASHQTFPLCTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEGRDHQALAKAVQVHQDTLRTMYFA 4z4d A 1.60 BS01 NUC B 1 K65 P67 R68 V70 R97 V177 G178 R179 R277 Y279 R280 F294 Y311 H316 H336 T337 Y338 I365 L522 G524 K525 T526 Y529 K533 Q545 C546 V547 Q548 N551 T559 N562 L563 K566 K570 T599 H600 P601 P602 A603 R635 E637 S672 Q675 K709 R710 H753 I756 Q757 T759 S760 R761 Y790 R792 C793 R795 S798 Y804 R812 K44 P46 R47 V49 R76 V150 G151 R152 R244 Y246 R247 F261 Y269 H274 H294 T295 Y296 I323 L480 G482 K483 T484 Y487 K491 Q503 C504 V505 Q506 N509 T517 N520 L521 K524 K528 T557 H558 P559 P560 A561 R593 E595 S630 Q633 K667 R668 H711 I714 Q715 T717 S718 R719 Y748 R750 C751 R753 S756 Y762 R770 3.1.26.- Q9UKV8 26359634 AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEIKRKYRVCNVTRRPASHQTFPECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEGRDHQALAKAVQVHQDTLRTMYFA 4z4d A 1.60 BS02 NUC D 1 D358 T361 S362 I365 K525 Q558 N562 K726 I756 Q757 F811 Y815 D316 T319 S320 I323 K483 Q516 N520 K684 I714 Q715 F769 Y773 3.1.26.- Q9UKV8 26359634 AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEIKRKYRVCNVTRRPASHQTFPECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEGRDHQALAKAVQVHQDTLRTMYFA 4z4f A 2.80 BS02 NUC D 1 D358 T361 S362 I365 R438 K525 P557 Q558 S561 K726 I756 F811 Y815 D314 T317 S318 I321 R394 K481 P513 Q514 S517 K682 I712 F767 Y771 3.1.26.- Q9UKV8 26359634 AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEIKRKYRVCNVTRRPASHQTFPECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEGRDHQALAKAVQVHQDTLRTMYFA 4z4h A 2.50 BS02 NUC D 1 D358 T361 S362 I365 K525 Q558 I756 Q757 F811 Y815 D315 T318 S319 I322 K482 Q515 I713 Q714 F768 Y772 3.1.26.- Q9UKV8 26359634 AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEIKRKYRVCNVTRRPASHQTFPLCTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDTGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEGRDHQALAKAVQVHQDTLRTMYFA 4z8m A 2.95 BS01 III C 1 H376 R392 F410 L456 L457 A458 P468 G470 F471 G472 Y473 H27 R43 F61 L107 L108 A109 P119 G121 F122 G123 Y124 6.3.2.- Q9Y4K3 NGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST 4z8m B 2.95 BS01 III D 1 H376 R392 F410 L457 A458 P468 K469 G470 F471 G472 Y473 H27 R43 F61 L108 A109 P119 K120 G121 F122 G123 Y124 6.3.2.- Q9Y4K3 NGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDLEH 4z8t A 1.64 BS01 SO4 A 1 R247 L248 S249 E253 R158 L159 S160 E164 Q6TKR8 26344722 QRKGTDEIYGLGSLPSAGPGRWEYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRGNTATGKTRIATKKIPVLAAALKKTAGKGCVNPDVFKSSLAKSETGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIASIVVDKRLSREYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFIADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTDLADKVIDKELIDRLENNIADPERAAKTRAALEKYSGKSWSAALAAHSELI 4z8t A 1.64 BS02 SO4 A 2 A163 G165 K166 T167 R287 A74 G76 K77 T78 R198 Q6TKR8 26344722 QRKGTDEIYGLGSLPSAGPGRWEYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRGNTATGKTRIATKKIPVLAAALKKTAGKGCVNPDVFKSSLAKSETGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIASIVVDKRLSREYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFIADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTDLADKVIDKELIDRLENNIADPERAAKTRAALEKYSGKSWSAALAAHSELI 4z8t A 1.64 BS03 SO4 A 3 T162 A163 R287 P294 T73 A74 R198 P205 Q6TKR8 26344722 QRKGTDEIYGLGSLPSAGPGRWEYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRGNTATGKTRIATKKIPVLAAALKKTAGKGCVNPDVFKSSLAKSETGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIASIVVDKRLSREYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFIADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTDLADKVIDKELIDRLENNIADPERAAKTRAALEKYSGKSWSAALAAHSELI 4z8t A 1.64 BS04 SO4 A 4 P276 R309 K360 P187 R220 K271 Q6TKR8 26344722 QRKGTDEIYGLGSLPSAGPGRWEYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRGNTATGKTRIATKKIPVLAAALKKTAGKGCVNPDVFKSSLAKSETGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIASIVVDKRLSREYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFIADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTDLADKVIDKELIDRLENNIADPERAAKTRAALEKYSGKSWSAALAAHSELI 4zmi A 2.30 BS01 MG A 1 L294 L297 Y299 L168 L171 Y173 P79005 26088418 SIWDIEKASLLVNDCQNIANMAEQKVMMVSAIFSESSKDIVNPESFSERLGKETVKDLYEFNEQLTTKYGLEFRTIFFSYIRKYDAYWCLFEDLEKPLKSIQFFTGLIDLLDNTNKHLTLRSIVLDALLSADEEDSFYGDALVLFEELVIRYFGTDSNPSIDASEFILSCLPYTSLDALNVVCGQVWKSQKICDFLKSTIGNTSNSPLQLRASFPAFVNAVIHFLLEFKNVRRLE 4zq9 A 2.60 BS01 NUC D 1 K101 M103 V104 R107 F108 Q111 R138 A141 G142 K93 M95 V96 R99 F100 Q103 R130 A133 G134 3.6.4.12 P03132 PGFYEIVIKVPSDISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHL 4zq9 A 2.60 BS02 NUC E 1 S102 M103 G106 S110 K136 R138 G142 G143 G144 N145 S94 M95 G98 S102 K128 R130 G134 G135 G136 N137 3.6.4.12 P03132 PGFYEIVIKVPSDISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHL 4zq9 A 2.60 BS03 MN A 1 E83 H90 H92 K160 E75 H82 H84 K152 3.6.4.12 P03132 PGFYEIVIKVPSDISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHL 4zq9 B 2.60 BS01 NUC D 1 M103 V104 R107 F108 Q111 R138 A141 M98 V99 R102 F103 Q106 R133 A136 3.6.4.12 P03132 PGFYEIVIKVPSDLDGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLT 4zq9 B 2.60 BS02 NUC E 1 S102 M103 G106 K136 R138 G142 G143 G144 N145 S97 M98 G101 K131 R133 G137 G138 G139 N140 3.6.4.12 P03132 PGFYEIVIKVPSDLDGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLT 4ztu A 3.30 BS01 NUC T 1 S306 R309 K496 K498 K561 S593 Q595 M596 R597 N803 R807 T849 I850 V855 P857 T861 G952 Y955 G956 G958 F961 M1093 T1094 S1095 N1098 Q1102 S217 R220 K383 K385 K429 S461 Q463 M464 R465 N590 R594 T636 I637 V642 P644 T648 G739 Y742 G743 G745 F748 M848 T849 S850 N853 Q857 P54098 26056153 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFAVAVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 4ztu A 3.30 BS02 NUC P 1 R579 S764 P765 K768 D769 N803 R853 L860 T861 A862 N864 R869 H1134 R447 S551 P552 K555 D556 N590 R640 L647 T648 A649 N651 R656 H889 P54098 26056153 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFAVAVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 4ztu A 3.30 BS03 MG A 1 D890 V891 D1135 D677 V678 D890 P54098 26056153 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFAVAVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 4ztu A 3.30 BS04 DCT A 1 R853 D890 V891 D892 S893 Q894 E895 H932 K947 Y951 D1135 R640 D677 V678 D679 S680 Q681 E682 H719 K734 Y738 D890 P54098 26056153 MLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFAVAVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATALGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 4zu9 A 3.19 BS01 GNP A 1 V12 D13 G15 K16 T17 T18 G38 S40 P63 G64 K117 D119 K120 A151 V152 V12 D13 G15 K16 T17 T18 G38 S40 P63 G64 K117 D119 K120 A151 V152 O67141 26304550 MKYILFATAGHVDHGKTTLIKTLTGIDTDRLPEEKKRGLSIDIGFAYIDFPDINTRLEIIDVPGHERFIKNAIAGICSASGLILVVDPNEGIMPQTIEHLRVAKSFGIKHGIAVLTKMDKVDEELAHIAEEELIAFLEKEEMNMEIVKVSAVTGQGIEDLKNSIKKLLESINNLNKHKPLRIFVDSAFVVKGYGTVLRGSCFEGEVKEGDKVVVEPIGVISRVRKMQNHGVFVKKAVAGERIALNLPEVDAKKVKRGFLILKPESYEKSNVLIVKTEIDLKPGKIYQVFFGMRETVGKISVIDKGIYLVRLKENAIVRRGDKLVVLDSSGNFLGGAEVLHPKVRVTKKAFIKKNIKDLLENFECYLLKERGPIGLKLEFFKRITGVSPKVANLKPESIEIRGVYYLKGFIENLKLKIKKFLDTELQNAFGVDKEKVKSMFSLNEELLKYILDELKTYKIVNELIIDERKSDLEKNEDFQKLMSILKGGIKEEREIILEGIPKEILTLSIKRKYAHRIGEYLIISDELLKKYINELKELGKTFNVQQAKNKLGLTRKYLIPLLEYLDYLGLTVREGNERRWKR 4zu9 A 3.19 BS02 MG A 1 T17 S40 T17 S40 O67141 26304550 MKYILFATAGHVDHGKTTLIKTLTGIDTDRLPEEKKRGLSIDIGFAYIDFPDINTRLEIIDVPGHERFIKNAIAGICSASGLILVVDPNEGIMPQTIEHLRVAKSFGIKHGIAVLTKMDKVDEELAHIAEEELIAFLEKEEMNMEIVKVSAVTGQGIEDLKNSIKKLLESINNLNKHKPLRIFVDSAFVVKGYGTVLRGSCFEGEVKEGDKVVVEPIGVISRVRKMQNHGVFVKKAVAGERIALNLPEVDAKKVKRGFLILKPESYEKSNVLIVKTEIDLKPGKIYQVFFGMRETVGKISVIDKGIYLVRLKENAIVRRGDKLVVLDSSGNFLGGAEVLHPKVRVTKKAFIKKNIKDLLENFECYLLKERGPIGLKLEFFKRITGVSPKVANLKPESIEIRGVYYLKGFIENLKLKIKKFLDTELQNAFGVDKEKVKSMFSLNEELLKYILDELKTYKIVNELIIDERKSDLEKNEDFQKLMSILKGGIKEEREIILEGIPKEILTLSIKRKYAHRIGEYLIISDELLKKYINELKELGKTFNVQQAKNKLGLTRKYLIPLLEYLDYLGLTVREGNERRWKR 4zu9 A 3.19 BS03 CYS A 1 R30 R198 H229 R241 R30 R198 H229 R241 O67141 26304550 MKYILFATAGHVDHGKTTLIKTLTGIDTDRLPEEKKRGLSIDIGFAYIDFPDINTRLEIIDVPGHERFIKNAIAGICSASGLILVVDPNEGIMPQTIEHLRVAKSFGIKHGIAVLTKMDKVDEELAHIAEEELIAFLEKEEMNMEIVKVSAVTGQGIEDLKNSIKKLLESINNLNKHKPLRIFVDSAFVVKGYGTVLRGSCFEGEVKEGDKVVVEPIGVISRVRKMQNHGVFVKKAVAGERIALNLPEVDAKKVKRGFLILKPESYEKSNVLIVKTEIDLKPGKIYQVFFGMRETVGKISVIDKGIYLVRLKENAIVRRGDKLVVLDSSGNFLGGAEVLHPKVRVTKKAFIKKNIKDLLENFECYLLKERGPIGLKLEFFKRITGVSPKVANLKPESIEIRGVYYLKGFIENLKLKIKKFLDTELQNAFGVDKEKVKSMFSLNEELLKYILDELKTYKIVNELIIDERKSDLEKNEDFQKLMSILKGGIKEEREIILEGIPKEILTLSIKRKYAHRIGEYLIISDELLKKYINELKELGKTFNVQQAKNKLGLTRKYLIPLLEYLDYLGLTVREGNERRWKR 4zxl A 2.60 BS02 NAG H 1 G187 F188 Y189 K218 D297 N298 Y335 V370 W394 N396 D401 N429 G149 F150 Y151 K180 D259 N260 Y297 V332 W356 N358 D363 N391 3.2.1.169,3.2.1.52 Q0TR53 26348912 NQVLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTANNIEINSENDPNSTTLIIGEVDDDIPELDEALNGTTAENLKEEGYALVSNDGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGFYGTPWTHQDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPESEMQRMQELINASAENKVDFVFGISPGIDIRFDGDAGEEDFNHLITKAESLYDMGVRSFAIYWDNIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTGAMVSNGQPRAYTRIFAETVDPSIEVMWTGPGVVTNEIPLSDAQLISGIYDRNMAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSKISIHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNKTWAKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNNLKANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKEIAQNKLNTALSSFAVISEKVAQSFIQEAL 4zzt A 1.56 BS01 MG A 1 D64 N206 D63 N201 3.2.1.176 A0A088T0J9 26367132 QIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzt A 1.56 BS02 SGC A 1 R251 D259 R267 R399 R246 D254 R262 R394 3.2.1.176 A0A088T0J9 26367132 QIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzt A 1.56 BS03 SGC A 2 T246 R251 P258 D259 W380 T241 R246 P253 D254 W375 3.2.1.176 A0A088T0J9 26367132 QIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzt A 1.56 BS04 BGC A 1 Q175 E212 T246 W371 Q174 E207 T241 W366 3.2.1.176 A0A088T0J9 26367132 QIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzt A 1.56 BS05 SGC A 3 W38 R107 Y145 Y171 D173 Y247 S369 W371 W37 R106 Y144 Y170 D172 Y242 S364 W366 3.2.1.176 A0A088T0J9 26367132 QIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzt A 1.56 BS06 SGC A 4 N37 W38 R107 D179 L180 S201 N36 W37 R106 D178 L179 S196 3.2.1.176 A0A088T0J9 26367132 QIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzt A 1.56 BS07 BGC A 2 N37 W38 V104 K181 N200 N36 W37 V103 K180 N195 3.2.1.176 A0A088T0J9 26367132 QIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzu A 1.44 BS02 BGC A 1 Q175 H228 T246 R251 P258 D259 W380 Q175 H228 T246 R251 P258 D259 W380 3.2.1.176 A0A088T0J9 26367132 EQIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPASNSANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzu A 1.44 BS03 BGC A 2 G53 Q101 K102 N103 N200 G53 Q101 K102 N103 N200 3.2.1.176 A0A088T0J9 26367132 EQIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPASNSANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzu A 1.44 BS06 SGC A 4 R107 Y145 Y171 S369 W371 R107 Y145 Y171 S369 W371 3.2.1.176 A0A088T0J9 26367132 EQIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPASNSANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 4zzv A 1.37 BS01 MG A 1 P177 R178 D179 Y247 P176 R177 D178 Y246 3.2.1.176 A0A088T0J9 26367132 QIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPASNSANSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFS 4zzw A 1.50 BS01 CBI A 1 H228 T246 R251 P258 D259 R267 D343 W380 R399 H225 T243 R248 P255 D256 R264 D340 W377 R396 3.2.1.176 A0A088T0J9 26367132 EQIGTLTTETHPPLTWQTCTSGGSCTTNNGKVVLDANWRWLHSTSGSTNCYTGNTWNTTLCPDDTTCAQNCALDGADYEGTYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCGLNGALYMVPMAADGGVSNEPNNKAGAQYGVGYCDSQCPRDLKFIAGSANVQGWEPASNSGLGGNGSCCAELDIWEANSISAALTPHSADTVTQTVCNGDDCGGTYSNDRYSGTTDPDGCDFNSYRQGDTSFYGPGKTVDTNSKFTVVTQFLTDSSGNLNEIKRFYVQNGVVIPNSQSTIAGISGNSITQDYCTAQKQVFGDTNTWEDHGGFQSMTNAFKAGMVLVMSLWDDYYADMLWLDSVAYPTDADPSTPGVARGTCSTTSGVPSDIESSAASAYVIYSNIKVGPINSTFSGT 5a69 A 2.20 BS01 OGN A 1 R94 D222 E223 W266 W306 Y308 Y309 W339 W373 D375 R88 D216 E217 W255 W267 Y269 Y270 W298 W332 D334 C1CH75 RFTGLSLKQTQAIEVLKHISLPVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLADKVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNRLLMCQHLERVLDIADKYGFHCQMWSDMFDRVTLVYWDYYQDSEEKYNRNFRNHHKIDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIYTT 5a6a A 2.69 BS01 NGT A 1 R94 H169 D222 E223 W266 W306 Y308 W339 W373 D375 R89 H164 D217 E218 W261 W301 Y303 W334 W368 D370 3.2.1.52 C1CH75 TGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSADGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYAKDFAATTANQWHTIATASTIYTT 5a6a B 2.69 BS01 NGT B 1 R94 W266 W306 Y308 W339 W373 D375 R92 W264 W285 Y287 W318 W352 D354 3.2.1.52 C1CH75 VRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLAEADVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFTRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFAATTANQWHTIATASTIYTT 5a6b A 1.77 BS01 OAN A 1 R94 D222 W266 W306 Y308 Y309 W339 W373 D375 R95 D223 W267 W292 Y294 Y295 W325 W359 D361 C1CH75 SMVRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIYTT 5a6b A 1.77 BS02 MG A 1 S38 R53 K54 Q57 S39 R54 K55 Q58 C1CH75 SMVRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIYTT 5a6b B 1.77 BS02 MG B 1 R571 S574 R575 R562 S565 R566 C1CH75 SMASMVRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIYTT 5a6b D 1.77 BS01 OAN D 1 R94 W266 W306 Y308 Y309 W339 W373 D375 R95 W267 W296 Y298 Y299 W329 W363 D365 C1CH75 SMVRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKMSIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIYTT 5a6k A 2.10 BS01 NSG A 1 R94 D222 E223 W266 W306 Y308 W339 W373 D375 R94 D222 E223 W266 W306 Y308 W339 W373 D375 3.2.1.52 C1CH75 MVRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSADGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIYTT 5a72 A 2.60 BS01 NUC C 1 A22 D23 G24 C25 N27 Q29 R33 R43 F49 Q50 S51 R73 M77 E79 T139 D140 G141 R144 T145 I146 A17 D18 G19 C20 N22 Q24 R28 R38 F44 Q45 S46 R68 M72 E74 T134 D135 G136 R139 T140 I141 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLNLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a72 A 2.60 BS02 NUC D 1 D23 R33 D35 Y36 L37 Q41 R43 R71 R73 N74 D75 G84 K120 K142 K143 D18 R28 D30 Y31 L32 Q36 R38 R66 R68 N69 D70 G79 K115 K137 K138 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLNLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a72 B 2.60 BS01 NUC C 1 D23 R33 D35 Y36 L37 Q41 R43 R71 R73 N74 G84 K120 D140 K142 K143 D18 R28 D30 Y31 L32 Q36 R38 R66 R68 N69 G79 K115 D135 K137 K138 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLNLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVVS 5a74 A 2.50 BS01 NUC C 1 D23 F49 Q50 S51 M77 D18 F44 Q45 S46 M72 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a74 A 2.50 BS02 NUC D 1 R33 D35 Y36 L37 Q41 R43 R71 R73 N74 D75 V83 G84 K120 D140 K142 K143 R28 D30 Y31 L32 Q36 R38 R66 R68 N69 D70 V78 G79 K115 D135 K137 K138 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a74 A 2.50 BS03 NUC E 1 A22 D23 G24 C25 N27 Q29 R43 F49 R73 E79 K102 T139 D140 G141 K143 R144 T145 I146 A17 D18 G19 C20 N22 Q24 R38 F44 R68 E74 K97 T134 D135 G136 K138 R139 T140 I141 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a74 A 2.50 BS04 MN F 1 D23 Q50 D18 Q45 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a74 B 2.50 BS01 NUC C 1 R33 D35 Y36 L37 Q41 R71 R73 N74 D75 V83 G84 K143 R28 D30 Y31 L32 Q36 R66 R68 N69 D70 V78 G79 K138 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVVS 5a74 B 2.50 BS02 NUC D 1 D23 F49 Q50 S51 R73 M77 D18 F44 Q45 S46 R68 M72 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVVS 5a74 B 2.50 BS03 NUC F 1 A22 D23 G24 C25 N27 Q29 R43 F49 R73 E79 T139 D140 G141 R144 T145 I146 A17 D18 G19 C20 N22 Q24 R38 F44 R68 E74 T134 D135 G136 R139 T140 I141 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVVS 5a77 A 2.50 BS01 NUC C 1 D23 Q50 S51 M77 D18 Q45 S46 M72 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a77 A 2.50 BS02 NUC D 1 R33 D35 Y36 L37 Q41 R43 T69 R71 R73 N74 V83 G84 K120 R28 D30 Y31 L32 Q36 R38 T64 R66 R68 N69 V78 G79 K115 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a77 B 2.50 BS03 NUC F 1 A22 G24 C25 N27 Q29 R33 R43 F49 R73 E79 K102 T139 G141 K143 R144 T145 I146 A17 G19 C20 N22 Q24 R28 R38 F44 R68 E74 K97 T134 G136 K138 R139 T140 I141 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVVS 5a77 B 2.50 BS04 MG B 1 A22 D23 A17 D18 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVVS 5a78 A 2.50 BS01 NUC C 1 D23 C25 N27 Q29 R33 R43 F49 Q50 S51 R73 M77 E79 T139 D140 G141 K143 R144 T145 I146 D18 C20 N22 Q24 R28 R38 F44 Q45 S46 R68 M72 E74 T134 D135 G136 K138 R139 T140 I141 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a78 A 2.50 BS02 NUC D 1 D35 Y36 L37 Q41 R43 T69 R71 R73 N74 G84 K120 K143 D30 Y31 L32 Q36 R38 T64 R66 R68 N69 G79 K115 K138 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV 5a78 B 2.50 BS01 NUC C 1 R33 D35 Y36 L37 Q41 R71 R73 N74 D75 V83 G84 D140 K142 K143 R28 D30 Y31 L32 Q36 R66 R68 N69 D70 V78 G79 D135 K137 K138 3.1.-.- P56347 26363068 NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVVS 5ac4 A 2.08 BS01 NGA A 1 R94 D222 Q223 W266 W306 Y308 W339 W373 D375 R93 D221 Q222 W265 W305 Y307 W338 W372 D374 3.2.1.52 C1CH75 VRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDQAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSADGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIYTT 5ac5 B 1.84 BS01 NAG B 1 R94 W266 W306 Y308 W339 W373 D375 R93 W265 W291 Y293 W324 W358 D360 3.2.1.52 C1CH75 VRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYAKDFAATTANQWHTIATASTIYTT 5ac9 1 3.20 BS01 III 4 1 F34 D37 D75 R179 K181 R182 F34 D37 D75 R157 K159 R160 Q6PMW3 TTSAGESADPVTATVENYGGETQVQRRQHTDVSFILDRFVKVTPKDQINVLDLMQTPAHTLVGALLRTATYYFADLEVAVKHEGNLTWVPNGAPEAALDNTTNPTAYHKAPLTRLALPYTAPHRVLATVYNGESRALPTSFNYGAIKATRVTELLYRMKRAETYCPRPLLAIHPDQARHKQKIVAP 5ac9 1 3.20 BS02 III 4 2 T1 P10 V11 T12 N17 P188 T1 P10 V11 T12 N17 P166 Q6PMW3 TTSAGESADPVTATVENYGGETQVQRRQHTDVSFILDRFVKVTPKDQINVLDLMQTPAHTLVGALLRTATYYFADLEVAVKHEGNLTWVPNGAPEAALDNTTNPTAYHKAPLTRLALPYTAPHRVLATVYNGESRALPTSFNYGAIKATRVTELLYRMKRAETYCPRPLLAIHPDQARHKQKIVAP 5aca 1 3.50 BS01 III 4 1 A33 D37 D75 A116 R184 K186 R187 A33 D37 D75 A116 R160 K162 R163 Q1L764 TTSSGEGADVVTTDPSTHGGAVTEKKRVHTDVAFVMDRFTHVLTNRTAFAVDLMDTNEKTLVGALLRAATYYFCDLEIACLGEHERVWWQPNGAPRTTTLRDNPMVFSHNNVTRFAVPYTAPHRLLSTRYNGECKYTQKLPSTFNFGYVTADKPVDVYYRMKRAELYCPRPLLPGYDHADRDRFDSPIG 5aca 1 3.50 BS02 III 4 2 T1 T2 S3 V10 T12 P193 T1 T2 S3 V10 T12 P169 Q1L764 TTSSGEGADVVTTDPSTHGGAVTEKKRVHTDVAFVMDRFTHVLTNRTAFAVDLMDTNEKTLVGALLRAATYYFCDLEIACLGEHERVWWQPNGAPRTTTLRDNPMVFSHNNVTRFAVPYTAPHRLLSTRYNGECKYTQKLPSTFNFGYVTADKPVDVYYRMKRAELYCPRPLLPGYDHADRDRFDSPIG 5aca 2 3.50 BS01 III 4 1 R43 P44 R167 R31 P32 R155 Q1L764 RILTTRHGTTTSTTQSSVGITYGYADADSFRPGPNTSGLETRVEQAERFFKEKLFDWTSDKPFGTLYVLELPKDHKGIYGYLTDAYTYMRNGWDVQVSATSTQFNGGSLLVAMVPELCSLKDREEFQLSLYPHQFINPRTNTTAHIQVPYLGVNRHDQGKRHQAWSLVVMVLTPLTTEAQMQSGTVEVYANIAPTNVFVAGEKPAKQ 5aca 2 3.50 BS02 III 4 3 Y36 A37 D38 Y24 A25 D26 Q1L764 RILTTRHGTTTSTTQSSVGITYGYADADSFRPGPNTSGLETRVEQAERFFKEKLFDWTSDKPFGTLYVLELPKDHKGIYGYLTDAYTYMRNGWDVQVSATSTQFNGGSLLVAMVPELCSLKDREEFQLSLYPHQFINPRTNTTAHIQVPYLGVNRHDQGKRHQAWSLVVMVLTPLTTEAQMQSGTVEVYANIAPTNVFVAGEKPAKQ 5adz A 2.20 BS01 FAD A 1 W96 H189 P234 I235 G236 G237 G238 T239 S240 V241 G244 L245 P302 D303 S304 S308 T309 G311 G312 W313 S315 T316 A318 S319 E368 G369 G372 V373 I374 A512 H616 N656 W16 H97 P142 I143 G144 G145 G146 T147 S148 V149 G152 L153 P210 D211 S212 S216 T217 G219 G220 W221 S223 T224 A226 S227 E276 G277 G280 V281 I282 A420 H524 N564 2.5.1.26 P97275 26322624 GIIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLDHKTPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5adz A 2.20 BS02 KQS A 1 D303 I511 R515 G525 E526 S527 Y578 Y580 F581 A582 H616 H617 D211 I419 R423 G433 E434 S435 Y486 Y488 F489 A490 H524 H525 2.5.1.26 P97275 26322624 GIIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLDHKTPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5adz B 2.20 BS01 FAD B 1 W96 H189 P234 I235 G236 G237 G238 T239 S240 V241 G244 L245 P302 D303 S304 S308 T309 G312 W313 S315 T316 A318 S319 E368 G369 G372 V373 I374 A512 H616 N654 N656 W16 H95 P140 I141 G142 G143 G144 T145 S146 V147 G150 L151 P208 D209 S210 S214 T215 G218 W219 S221 T222 A224 S225 E274 G275 G278 V279 I280 A396 H500 N538 N540 2.5.1.26 P97275 26322624 GIIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5adz B 2.20 BS02 KQS B 1 D303 I511 R515 G525 E526 S527 Y578 A582 H616 H617 D209 I395 R399 G409 E410 S411 Y462 A466 H500 H501 2.5.1.26 P97275 26322624 GIIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5adz D 2.20 BS02 KQS D 1 D303 I511 M514 R515 G525 E526 S527 Y578 H616 H617 D223 I405 M408 R409 G419 E420 S421 Y472 H510 H511 2.5.1.26 P97275 26322624 GIIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKDWIQNTFGINLDHKTTSKASLNPSDTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL 5ap0 A 2.15 BS01 AU5 A 1 I531 V539 A551 I586 M602 E603 C604 G605 N606 I607 D608 S611 L654 I663 I17 V25 A37 I72 M88 E89 C90 G91 N92 I93 D94 S97 L140 I149 2.7.12.1 P33981 26202014 FQSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQVGTVNYMPPEAIKDMISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 5ap1 A 2.05 BS01 O38 A 1 I531 V539 Q541 A551 I586 M602 C604 G605 N606 I607 D608 S611 L654 I663 M671 Q672 P673 I17 V25 Q27 A37 I72 M88 C90 G91 N92 I93 D94 S97 L140 I149 M157 Q158 P159 2.7.12.1 P33981 26202014 FQSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDVGTVNYMPPEAIKDMSSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQT 5ap2 A 2.80 BS01 PWU A 1 I531 A551 K553 E571 I586 M602 E603 C604 G605 N606 I607 D608 L654 I663 P673 I16 A36 K38 E56 I71 M87 E88 C89 G90 N91 I92 D93 L139 I148 P158 2.7.12.1 P33981 26202014 QSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDGTVNYMPPEAIKDMSPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 5ap3 A 2.70 BS01 AU5 A 1 I531 G532 V539 Q541 A551 I586 M602 E603 C604 G605 N606 I607 D608 L654 I663 I16 G17 V24 Q26 A36 I71 M87 E88 C89 G90 N91 I92 D93 L139 I148 2.7.12.1 P33981 26202014 QSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNGWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANSQVGTVNYMPPEAIKDISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 5ap4 A 2.85 BS01 O38 A 1 I531 V539 Q541 A551 I586 M602 C604 G605 N606 I607 D608 L654 I663 M671 P673 I17 V25 Q27 A37 I72 M88 C90 G91 N92 I93 D94 L140 I149 M156 P158 2.7.12.1 P33981 26202014 FQSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNGWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANMQPDQVGTVNYMPPEAIKDISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 5ap5 A 2.80 BS01 7RO A 1 I531 V539 A551 K553 I586 M602 E603 C604 G605 N606 D608 L654 I663 I17 V25 A37 K39 I72 M88 E89 C90 G91 N92 D94 L140 I149 2.7.12.1 P33981 26202014 FQSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNGWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIAGTVNYMPPEAIKDMISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 5ap5 A 2.80 BS02 1KA A 1 K553 V555 Y568 E571 A668 K39 V41 Y54 E57 A154 2.7.12.1 P33981 26202014 FQSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNGWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIAGTVNYMPPEAIKDMISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 5ap6 A 2.10 BS01 PWU A 1 I531 G532 V539 A551 K553 I586 M602 E603 G605 N606 I607 D608 S611 L654 I663 M671 P673 I16 G17 V24 A36 K38 I71 M87 E88 G90 N91 I92 D93 S96 L139 I148 M156 P158 2.7.12.1 P33981 26202014 QSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMEWGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDDSQVGTVNYMPPEAIKDMKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 5ap7 A 2.45 BS01 SVE A 1 I531 S537 V539 Q541 A551 K553 I586 M602 E603 W604 G605 N606 D608 S611 A651 N652 L654 I663 D664 I23 S29 V31 Q33 A43 K45 I78 M94 E95 W96 G97 N98 D100 S103 A143 N144 L146 I155 D156 2.7.12.1 P33981 26202014 GTENLYFQSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMEWGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPVGTVNYMPPEAIKDISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 5aui A 1.50 BS01 FES A 1 F38 S39 C40 R41 G43 A44 C45 C48 L76 C78 F38 S39 C40 R41 G43 A44 C45 C48 L76 C78 P0A3C9 26348494 ATYKVTLVRPDGSETTIDVPEDEYILDVAEEQGLDLPFSCRAGACSTCAGKLLEGEVDQSDQSFLDDDQIEKGFVLTCVAYPRSDCKILTNQEEELY 5awb A 2.10 BS01 M0A A 1 F346 Y348 G351 S352 Y353 V378 F405 R429 F302 Y304 G307 S308 Y309 V334 F361 R385 Q9NR97 26351878 SRSYPCDEKKQSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSL 5awd A 2.05 BS01 IDQ A 1 Y348 G351 S352 Y353 G376 V378 F405 R429 Y304 G307 S308 Y309 G332 V334 F361 R385 Q9NR97 26351878 SRSYPCDEKKQSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE 5bpy A 2.31 BS01 4UQ A 1 L408 G409 V416 A428 E475 Y476 M477 A478 N479 G480 C481 L528 L14 G15 V22 A34 E81 Y82 M83 A84 N85 G86 C87 L134 2.7.10.2 Q06187 26320619 MEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDE 5bq0 A 1.57 BS01 4US A 1 L408 G409 T410 G411 V416 A428 K430 T474 E475 Y476 M477 A478 N479 G480 C481 E488 L528 L20 G21 T22 G23 V28 A40 K42 T86 E87 Y88 M89 A90 N91 G92 C93 E100 L140 2.7.10.2 Q06187 26320619 GLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES 5bsk A 2.61 BS01 4X7 A 1 I135 D137 T138 G139 T141 K165 F186 V187 D193 I110 D112 T113 G114 T116 K140 F161 V162 D168 2.4.2.8 P00492 SPGVVISDDGYDLDLFAIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVAVISETGKAKYKA 5bsk A 2.61 BS02 MG A 1 G69 E133 D134 G64 E108 D109 2.4.2.8 P00492 SPGVVISDDGYDLDLFAIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVAVISETGKAKYKA 5bsk B 2.61 BS01 4X7 B 1 I135 D137 T138 G139 K140 T141 K165 F186 V187 L192 D193 I109 D111 T112 G113 K114 T115 K139 F160 V161 L166 D167 2.4.2.8 P00492 PGVVISDDGYDLDLFAIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVAVISETGKAKYKA 5bsk B 2.61 BS02 MG B 1 K68 G69 E133 D134 K62 G63 E107 D108 2.4.2.8 P00492 PGVVISDDGYDLDLFAIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVAVISETGKAKYKA 5bsk D 2.61 BS01 4X7 D 1 D134 I135 D137 T138 G139 T141 K165 K185 F186 V187 D193 D110 I111 D113 T114 G115 T117 K141 K157 F158 V159 D165 2.4.2.8 P00492 PGVVISDDEPGYDLDLFAIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVAVISETGKAKYK 5bsk D 2.61 BS02 MG D 1 E133 D134 E109 D110 2.4.2.8 P00492 PGVVISDDEPGYDLDLFAIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVAVISETGKAKYK 5bxc A 1.40 BS01 DA8 A 1 H233 F236 T245 W300 E303 D326 L329 H348 H176 F179 T188 W243 E246 D269 L272 H291 2.4.1.40,2.4.1.37 P16442 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP 5bxc A 1.40 BS02 MN A 1 D211 D213 D154 D156 2.4.1.40,2.4.1.37 P16442 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP 5bxc A 1.40 BS03 UDP A 1 F121 A122 I123 Y126 V184 R188 D211 V212 D213 K346 R352 F64 A65 I66 Y69 V127 R131 D154 V155 D156 K289 R295 2.4.1.40,2.4.1.37 P16442 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP 5byg A 2.50 BS01 NUC E 1 K101 M103 V104 R107 F108 Q111 R138 N139 G140 A141 G142 K81 M83 V84 R87 F88 Q91 R118 N119 G120 A121 G122 Q89268 MPGFYEIVIKVPSEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQE 5byg A 2.50 BS03 MG A 1 E83 H92 E63 H72 Q89268 MPGFYEIVIKVPSEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQE 5byg B 2.50 BS02 NUC F 1 S102 M103 G106 R107 K136 R138 G142 G143 G144 N145 S96 M97 G100 R101 K130 R132 G136 G137 G138 N139 Q89268 MPGFYEIVIKVPSDGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQEQNKENQ 5byg B 2.50 BS03 MG B 1 E83 H90 H92 E77 H84 H86 Q89268 MPGFYEIVIKVPSDGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQEQNKENQ 5byg C 2.50 BS02 NUC H 1 S102 M103 G106 K136 G142 G143 G144 N145 S95 M96 G99 K129 G135 G136 G137 N138 Q89268 MPGFYEIVIKVPSGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQ 5byg C 2.50 BS03 MG C 1 E83 H92 K160 E76 H85 K153 Q89268 MPGFYEIVIKVPSGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQ 5byg D 2.50 BS01 NUC G 1 K101 M103 V104 R107 Q111 R138 N139 A141 K74 M76 V77 R80 Q84 R111 N112 A114 Q89268 MPGFYEIVIKPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQEQNKENQ 5byg D 2.50 BS02 NUC H 1 S102 M103 G106 S110 K136 G142 G143 G144 N145 S75 M76 G79 S83 K109 G115 G116 G117 N118 Q89268 MPGFYEIVIKPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQEQNKENQ 5bym A 2.71 BS01 NUC C 1 Q222 R226 Q229 N263 Y264 Q267 Y297 R300 Q303 L339 N340 N342 H343 Q346 H378 C381 Q384 Q413 F414 N416 Y417 Q420 K451 F452 S454 N455 E458 N516 F517 N519 Y520 Q523 S583 Y584 K587 Q21 R25 Q28 N62 Y63 Q66 Y96 R99 Q102 L138 N139 N141 H142 Q145 H177 C180 Q183 Q212 F213 N215 Y216 Q219 K250 F251 S253 N254 E257 N302 F303 N305 Y306 Q309 S347 Y348 K351 P39016 MVEISALPLRDLDYIKLATDQFGCRFLQKKLETPSESNMVRDLMYEQIKPFFLDLILDPFGNYLVQKLCDYLTAEQKTLLIQTIYPNVFQISINQYGTRSLQKIIDTVDNEVQIDLIIKGFSQEFTSIEQVVTLINDLNGNHVIQKCIFKFSPSKFGFIIDAIVEQNNIITISTHKHGCCVLQKLLSVCTLQQIFKISVKIVQFLPGLINDQFGNYIIQFLLDIKELDFYLLAELFNRLSNELCQLSCLKFSSNVVEKFIKKLFRIITGFIASDDVINASMNILLTTIDIFTVNLNVLIRDNFGNYALQTLLDVKNYSPLFCNDFSLKIGNLIVLTKELLPSIKTTSYAKKIKLKVKAYAEAT 5bz5 A 2.80 BS01 NUC B 1 Q222 R226 Q229 N263 Y264 Q267 Y297 R300 Q303 H343 K377 C380 C381 Q384 K385 F414 N416 Y417 Q420 K451 F452 S454 N455 E458 F517 N519 Y520 Q523 S583 Y584 K587 Q20 R24 Q27 N61 Y62 Q65 Y95 R98 Q101 H141 K175 C178 C179 Q182 K183 F212 N214 Y215 Q218 K249 F250 S252 N253 E256 F302 N304 Y305 Q308 S349 Y350 K353 P39016 VEISALPLRDLDYIKLATDQFGCRFLQKKLETPSESNMVRDLMYEQIKPFFLDLILDPFGNYLVQKLCDYLTAEQKTLLIQTIYPNVFQISINQYGTRSLQKIIDTVDNEVQIDLIIKGFSQEFTSIEQVVTLINDLNGNHVIQKCIFKFSPSKFGFIIDAIVEQNNIITISTHKHGCCVLQKLLSVCTLQQIFKISVKIVQFLPGLINDQFGNYIIQFLLDIKELDFYLLAELFNRLSNELCQLSCLKFSSNVVEKFIKKLFRIITGFIASDDVINASMNILLTTIDIFTVNLNVLIRDNFGNYALQTLLDVKNYSPLLGNFCNDFSLKIGNLIVLTKELLPSIKTTSYAKKIKLKVKAYAEATG 5bzu A 2.50 BS01 NUC B 1 Q222 R226 Q229 N263 Y264 Q267 Y297 R300 C380 C381 Q384 F414 N416 Y417 Q420 K451 F452 S454 N455 E458 N516 F517 N519 Y520 Q523 Y584 K587 Q19 R23 Q26 N60 Y61 Q64 Y94 R97 C177 C178 Q181 F211 N213 Y214 Q217 K248 F249 S251 N252 E255 N300 F301 N303 Y304 Q307 Y349 K352 P39016 EISALPLRDLDYIKLATDQFGCRFLQKKLETPSESNMVRDLMYEQIKPFFLDLILDPFGNYLVQKLCDYLTAEQKTLLIQTIYPNVFQISINQYGTRSLQKIIDTVDNEVQIDLIIKGFSQEFTSIEQVVTLINDLNGNHVIQKCIFKFSPSKFGFIIDAIVEQNNIITISTHKHGCCVLQKLLSVCTLQQIFKISVKIVQFLPGLINDQFGNYIIQFLLDIKELDFYLLAELFNRLSNELCQLSCLKFSSNVVEKFIKKLFRIITGFIASDDVINASMNILLTTIDIFTVNLNVLIRDNFGNYALQTLLDVKNYSPLLGNFCNDFSLKIGNLIVLTKELLPSIKTTSYAKKIKLKVKAYAEAT 5bzv A 2.35 BS01 NUC B 1 Q222 R226 Q229 N263 Y264 Q267 Y297 T299 R300 Q303 N342 H343 Q346 K377 H378 C380 C381 Q384 F414 N416 Y417 Q420 K451 F452 S454 N455 E458 N516 F517 N519 Y520 Q523 S583 Y584 K587 Q19 R23 Q26 N60 Y61 Q64 Y94 T96 R97 Q100 N139 H140 Q143 K174 H175 C177 C178 Q181 F211 N213 Y214 Q217 K248 F249 S251 N252 E255 N301 F302 N304 Y305 Q308 S348 Y349 K352 P39016 EISALPLRDLDYIKLATDQFGCRFLQKKLETPSESNMVRDLMYEQIKPFFLDLILDPFGNYLVQKLCDYLTAEQKTLLIQTIYPNVFQISINQYGTRSLQKIIDTVDNEVQIDLIIKGFSQEFTSIEQVVTLINDLNGNHVIQKCIFKFSPSKFGFIIDAIVEQNNIITISTHKHGCCVLQKLLSVCTLQQIFKISVKIVQFLPGLINDQFGNYIIQFLLDIKELDFYLLAELFNRLSNELCQLSCLKFSSNVVEKFIKKLFRIITGFIVASDDVINASMNILLTTIDIFTVNLNVLIRDNFGNYALQTLLDVKNYSPLLNFCNDFSLKIGNLIVLTKELLPSIKTTSYAKKIKLKVKAYAEAT 5c1g A 1.46 BS02 DA8 A 1 H233 S235 F236 T245 Y264 M266 W300 E303 D326 L329 K346 H348 H174 S176 F177 T186 Y205 M207 W241 E244 D267 L270 K287 H289 2.4.1.40,2.4.1.37 P16442 GEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQV 5c1g A 1.46 BS03 GDU A 1 F121 A122 I123 Y126 W181 V184 S185 R188 D211 V212 D213 M266 G267 G268 W300 H301 D302 E303 K346 F62 A63 I64 Y67 W122 V125 S126 R129 D152 V153 D154 M207 G208 G209 W241 H242 D243 E244 K287 2.4.1.40,2.4.1.37 P16442 GEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQV 5c1h A 1.55 BS02 GDU A 1 F121 A122 I123 Y126 D211 V212 D213 G267 W300 H301 D302 E303 K346 F60 A61 I62 Y65 D142 V143 D144 G198 W231 H232 D233 E234 K277 2.4.1.40,2.4.1.37 P16442 FMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYSMRRMEMISCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK 5c1h A 1.55 BS03 DA8 A 1 H233 S235 F236 T245 Y264 M266 W300 E303 D326 L329 H164 S166 F167 T176 Y195 M197 W231 E234 D257 L260 2.4.1.40,2.4.1.37 P16442 FMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYSMRRMEMISCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK 5c38 A 1.45 BS03 DA8 A 1 H233 G235 F236 T245 M266 W300 E303 D326 L329 K346 H163 G165 F166 T175 M196 W230 E233 D256 L259 K276 2.4.1.40,2.4.1.37 P16442 EFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAMRRMEMISFCERFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKN 5c3a A 1.33 BS02 URM A 1 F121 A122 I123 Y126 V184 R188 D211 V212 D213 H233 M266 W300 E303 K346 F60 A61 I62 Y65 V120 R124 D147 V148 D149 H169 M202 W236 E239 K282 2.4.1.40,2.4.1.37 P16442 FMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK 5c3b A 1.40 BS02 DA8 A 1 H233 S235 F236 T245 W300 E303 D326 L329 K346 H164 S166 F167 T176 W231 E234 D257 L260 K277 2.4.1.40,2.4.1.37 P16442 FMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK 5c3d A 1.39 BS02 URM A 1 F121 A122 I123 Y126 R188 D211 V212 D213 H233 M266 W300 E303 F60 A61 I62 Y65 R121 D144 V145 D146 H166 M199 W233 E236 2.4.1.40,2.4.1.37 P16442 FMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 5c47 A 1.39 BS02 DA8 A 1 H233 S235 F236 T245 M266 W300 E303 D326 K346 H174 S176 F177 T186 M207 W241 E244 D267 K287 2.4.1.40,2.4.1.37 P16442 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKN 5c48 A 1.46 BS02 DA8 A 1 H233 S235 F236 T245 M266 W300 E303 D326 L329 K346 H169 S171 F172 T181 M202 W236 E239 D262 L265 K282 2.4.1.40,2.4.1.37 P16442 GEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVGAYVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK 5c48 A 1.46 BS03 URM A 1 F121 A122 I123 K124 Y126 R188 D211 V212 D213 W300 H301 D302 E303 K346 F62 A63 I64 K65 Y67 R124 D147 V148 D149 W236 H237 D238 E239 K282 2.4.1.40,2.4.1.37 P16442 GEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVGAYVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK 5c4b A 1.54 BS02 DA8 A 1 H233 F236 T245 W300 E303 D326 L329 H176 F179 T188 W243 E246 D269 L272 2.4.1.40,2.4.1.37 P16442 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 5c4b A 1.54 BS03 UPG A 1 F121 A122 I123 Y126 W181 V184 S185 R188 D211 V212 D213 L266 G267 G268 D302 E303 F64 A65 I66 Y69 W124 V127 S128 R131 D154 V155 D156 L209 G210 G211 D245 E246 2.4.1.40,2.4.1.37 P16442 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 5c4c A 1.43 BS02 UPG A 1 F121 A122 I123 Y126 S185 R188 D211 V212 D213 M266 G267 A268 D302 E303 F64 A65 I66 Y69 S122 R125 D147 V148 D149 M202 G203 A204 D238 E239 2.4.1.40,2.4.1.37 P16442 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYSMRRMEMISFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK 5c6o A 3.00 BS01 4YH A 1 M33 Y36 N37 F60 M63 M64 M67 F150 F154 Q252 M31 Y34 N35 F58 M61 M62 M65 F148 F152 Q250 Q9KAX3 26246409 QKQQSERLGTEAIPKLLRSLSIPAMIGMFVMALYNVVDTIFISYAVGIEGVAGVTIAFPIMMIMMSMAGALGIGGASVISRRLGERRGEEANQVFGNILTVILVLSVIGFISAFTLLGPALQLFGATSVTQGYATDYLFPILLGSIFFFFAFAANNIIRSEGNATFAMVTMIVPAVLNILLDVLFIFGLNMGVLGASIATVIAQASVTGLVLRYFLTGKSTLSLHWSDLRMKGSVIKEVCLVGLPAFVQQSSASLMMIAINSMLLRFGSDFYVGVFGLVQRIMMFVMMPMMGIMQAMQPIVGYNYGAKQYSRLRETVMLGFKVATIFSIGIFALLMLFPEALLRVFTADREVIQAGVSAMHILFCVTFLIGAQIVAGGLYQSLGKPKQALILSLSRQIIFLIPLVLILPHIFGLSGVWWAFPIADVLSFILTVVLLYRDRNVFFLK 5c6p A 3.00 BS01 4YH A 1 A57 S61 Q284 S288 D356 P357 A53 S57 Q280 S284 D352 P353 Q5F9J8 26246409 LDRFSFSVFLKEIRLLTALALPMLLAQVAQVGIGFVDTVMAGGAGKEDLAAVALGSSAFATVYITFMGIMAALNPMIAQLYGAGKTGEAGETGRQGIWFGLILGIFGMILMWAAITPFRNWLTLSDYVEGTMAQYMLFTSLAMPAAMVHRALHAYASSLNRPRLIMLVSFAAFVLNVPLNYIFVYGKFGMPALGGAGCGVATMAVFWFSALALWIYIAKEKFFRPFGLTAKFGKPDWAVFKQIWKIGAPIGLSYFLEASAFSFIVFLIAPFGEDYVAAQQVGISLSGILYMIPQSVGSAGTVRIGFSLGRREFSRARYISGVSLVSGWVLAVITVLSLVLFRSPLASMYNDDPAVLSIASTVLLFAGLFQPADFTQCIASYALRGYKVTKVPMFIHAAAFWGCGLLPGYLLAYRFDMGIYGFWTALIASLTIAAVALVWCLEKYSMELVKSHKAVSSGL 5c8r A 1.45 BS03 UPG A 1 F121 A122 I123 Y126 R188 D211 V212 D213 M266 G267 G268 W300 H301 D302 F62 A63 I64 Y67 R120 D143 V144 D145 M198 G199 G200 W232 H233 D234 2.4.1.40,2.4.1.37 P16442 GEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPSFYGSSREAFTYERRPQSQAYIPKDEGDFYYMGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK 5ca9 A 2.80 BS01 MG A 1 S72 T95 S47 T70 3.6.5.5 Q9C0L9 QDAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMDELNRQQTTKGIWLAYSPVVSTTLGHTTSKSNILVMDVEGTDGRERGEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFTLDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLGDRLVVSNELFKPEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLTKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVVELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKGVYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFAVAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLDDEEDHCFAEIITEQEKLEVLAKFKKEVDAKYIETKRSIV 5ca9 A 2.80 BS02 ALF A 1 Q67 S68 K71 Q93 T94 T95 G126 Q42 S43 K46 Q68 T69 T70 G101 3.6.5.5 Q9C0L9 QDAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMDELNRQQTTKGIWLAYSPVVSTTLGHTTSKSNILVMDVEGTDGRERGEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFTLDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLGDRLVVSNELFKPEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLTKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVVELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKGVYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFAVAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLDDEEDHCFAEIITEQEKLEVLAKFKKEVDAKYIETKRSIV 5ca9 A 2.80 BS03 GDP A 1 S68 T69 G70 K71 S72 T73 V85 M86 E88 T95 W158 R204 D205 H254 K255 S43 T44 G45 K46 S47 T48 V60 M61 E63 T70 W133 R179 D180 H229 K230 3.6.5.5 Q9C0L9 QDAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMDELNRQQTTKGIWLAYSPVVSTTLGHTTSKSNILVMDVEGTDGRERGEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFTLDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLGDRLVVSNELFKPEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLTKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVVELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKGVYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFAVAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLDDEEDHCFAEIITEQEKLEVLAKFKKEVDAKYIETKRSIV 5cb2 A 2.90 BS01 MG A 1 S72 T95 D123 S47 T70 D98 3.6.5.5 Q9C0L9 QDAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMDELNRQQTTKGIWLAYSPVVSTTLGHTTSKSNILVMDVEGTDGRERGEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFTLDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLGDRLVVSNELFKPEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLTKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVVELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKGVYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFAVAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLDDEEDHCFAEIITEQEKLEVLAKFKKEVDAKYIETKRSIV 5cb2 A 2.90 BS02 GNP A 1 Q67 S68 T69 G70 K71 S72 T73 V85 M86 E88 Q93 T94 T95 G126 W158 R204 D205 H254 K255 Q42 S43 T44 G45 K46 S47 T48 V60 M61 E63 Q68 T69 T70 G101 W133 R179 D180 H229 K230 3.6.5.5 Q9C0L9 QDAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMDELNRQQTTKGIWLAYSPVVSTTLGHTTSKSNILVMDVEGTDGRERGEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFTLDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLGDRLVVSNELFKPEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLTKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVVELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKGVYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFAVAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLDDEEDHCFAEIITEQEKLEVLAKFKKEVDAKYIETKRSIV 5cf3 A 2.03 BS01 CA A 1 E18 K21 D23 V25 E32 E18 K21 D23 V25 E32 Q14U76 26349459 GSNNVNDLITVTKQMITEGIKDDGVIQAHDGEHIIYTSDFKIDNAVKAGDTMTVKYDKHTIPSDITDDFTPVDITDPSGEVIAKGTFDLNTKTITYKFTDYVDRYENVNAKLELNSYIDKKEVPNETNLNLTFATADKETSKNVKVEYQKPIVKDESNIQSIFSHLDTTKHEVEQTIYVNPLKLNAKNTNVTIKSGGVADNGDYYTGDGSTIIDSNTEIKVYKVASGQQLPQSNKIYDYSQYEDVTNSVTINKNYGTNMANINFGDIDSAYIVKVVSKYTPGAEDDLAVQQGVRMTTTNKYNYSSYAGYTNTILST 5cf3 A 2.03 BS02 CA A 2 N44 V46 V102 N44 V46 V102 Q14U76 26349459 GSNNVNDLITVTKQMITEGIKDDGVIQAHDGEHIIYTSDFKIDNAVKAGDTMTVKYDKHTIPSDITDDFTPVDITDPSGEVIAKGTFDLNTKTITYKFTDYVDRYENVNAKLELNSYIDKKEVPNETNLNLTFATADKETSKNVKVEYQKPIVKDESNIQSIFSHLDTTKHEVEQTIYVNPLKLNAKNTNVTIKSGGVADNGDYYTGDGSTIIDSNTEIKVYKVASGQQLPQSNKIYDYSQYEDVTNSVTINKNYGTNMANINFGDIDSAYIVKVVSKYTPGAEDDLAVQQGVRMTTTNKYNYSSYAGYTNTILST 5cfa A 1.45 BS01 III C 1 H29 D30 G31 P62 S63 D64 I65 T66 F69 N115 Y117 F163 Y205 E284 D285 Q290 Y309 T310 N311 T312 I313 L314 S315 T316 T317 D318 H27 D28 G29 P60 S61 D62 I63 T64 F67 N113 Y115 F161 Y203 E282 D283 Q288 Y307 T308 N309 T310 I311 L312 S313 T314 T315 D316 Q14U76 26349459 NNVNDLITVTKQMITEGIKDDGVIQAHDGEHIIYTSDFKIDNAVKAGDTMTVKYDKHTIPSDITDDFTPVDITDPSGEVIAKGTFDLNTKTITYKFTDYVDRYENVNAKLELNSYIDKKEVPNETNLNLTFATADKETSKNVKVEYQKPIVKDESNIQSIFSHLDTTKHEVEQTIYVNPLKLNAKNTNVTIKSGGVADNGDYYTGDGSTIIDSNTEIKVYKVASGQQLPQSNKIYDYSQYEDVTNSVTINKNYGTNMANINFGDIDSAYIVKVVSKYTPGAEDDLAVQQGVRMTTTNKYNYSSYAGYTNTILSTTDSGGGDGTVKP 5cil H 1.81 BS01 III P 1 T31 A33 W47 G50 V51 I52 L54 I56 N58 E95 L100C G100D K100E P100F T30 A32 W46 G49 V50 I51 L54 I56 N58 E98 L106 G107 K108 P109 VQLVQSGAEVKRPGSSVTVSCKASGGSFSTYALSWVRQAPGRGLEWMGGVIPLLTITNYAPRFQGRITITADRSTSTAYLELNSLRPEDTAVYYCAREGTTGDGDLGKPIGAFAHWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 5cin H 1.70 BS01 III P 1 T31 A33 G50 V51 I52 L53 L54 I56 N58 E95 G100A G100D K100E P100F T30 A32 G49 V50 I51 L53 L54 I56 N58 E98 G104 G105 K106 P107 VQLVQSGAEVKRPGSSVTVSCKASGGSFSTYALSWVRQAPGRGLEWMGGVIPLLTITNYAPRFQGRITITADRSTSTAYLELNSLRPEDTAVYYCAREGTTGSGGKPIGAFAHWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 5cx1 J 1.75 BS01 CLF I 1 C70 P72 G94 C95 Y98 T152 C153 S188 C69 P71 G93 C94 Y97 T151 C152 S187 1.18.6.1 26360912 SQQVDKIKASYPLFLDQDYKDMLAKKRDGFEEKYPQDKIDEVFQWTTTKEYQELNFQREALTVNPAKACQPLGAVLCALGFEKTMPYVHGSQGCVAYFRSYFNRHFREPVSCVSDSMTEDAAVFGGQQNMKDGLQNCKATYKPDMIAVSTTCMAEVIGDDLNAFINNSKKEGFIPDEFPVPFAHTPSFVGSHVTGWDNMFEGIARYFTLKSMDDKVVGSNKKINIVPGFETYLGNFRVIKRMLSEMGVGYSLLSDPEEVLDTPADGQFRMYAGGTTQEEMKDAPNALNTVLLQPWHLEKTKKFVEGTWKHEVPKLNIPMGLDWTDEFLMKVSEISGQPIPASLTKERGRLVDMMTDSHTWLHGKRFALWGDPDFVMGLVKFLLELGCEPVHILCHNGNERWKKAVDAILAASPYGKNATVYIGKDLWHLRSLVFTDKPDFMIGNSYGKFIQRDTLHKGKEFEVPLIRIGFPIFDRHHLHRSTTLGYEGAMQILTTLVNSILERLDEETRGMQATDYNHDLVR 5cxh A 1.90 BS01 55M A 1 L377 G378 G380 V385 A400 K402 M448 E449 M450 A451 E452 G454 P455 K458 L501 S511 D512 L15 G16 G18 V23 A38 K40 M86 E87 M88 A89 E90 G92 P93 K96 L139 S149 D150 2.7.10.2 P43405 26320624 VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVTDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNHHHH 5cy3 A 1.76 BS01 55Y A 1 L377 G378 G380 V385 A400 K402 M448 E449 M450 A451 E452 G454 P455 R498 N499 L501 S511 D512 L18 G19 G21 V26 A41 K43 M87 E88 M89 A90 E91 G93 P94 R137 N138 L140 S150 D151 2.7.10.2 P43405 26320624 PKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVTDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNEG 5czy A 2.20 BS01 SAM A 1 L125 R131 S171 Y172 R191 Y192 I193 N194 F195 Y233 E238 Y244 Y245 L247 L42 R48 S88 Y89 R108 Y109 I110 N111 F112 Y150 E155 Y161 Y162 L164 Q5ZUS4 26315269 DEWIDTSKIMLDLHIDNMSSSDYIPSAIDRTDLVMVQSVHLLRKTGGRGLFAREDIPKGTCIGIYTGEVYSEQEFEQYLKEHVGSDKSYAMYVGGRVIDAARKGNLTRYINFSDSQDNAEFVETTLNRKKVAKVITTKNIKAGQQLLINYNTYEEQASRYYYFLNPGDGWLSAQEFYQTYQSQYRLEQMPYNLEGFDLKAGDRVLMTQIGRIILANYSLAKEQELNASDIDLPFLKVGSDEKILDFDEADTFTPLMAACYLGQVENVKWLIEHGANIDQQQSHSGHCPLSLTLKGYSLAKDTQKYIDIIQLLIKNQVNLLVHDRSDKTFLHNAALVLNNLDFQSVVKFLIGQNPIDINEYFTYIDENDFDIVMHCYNNKLFDKALVLLAFYPDYFKRNYMSDNEGHNQFNINAFRKAIKDFNSNERSILLMQLRESGLHLPEDLLEQLG 5d6s A 2.65 BS01 SF4 A 1 G149 K150 N151 C184 C187 R188 C190 C243 P244 Y245 G149 K150 N151 C184 C187 R188 C190 C243 P244 Y245 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s A 2.65 BS02 SF4 A 2 C194 P195 C198 L199 M205 C210 L211 C236 I238 C239 C194 P195 C198 L199 M205 C210 L211 C236 I238 C239 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s A 2.65 BS03 B12 A 1 L30 L34 T44 E47 R54 T93 N95 D130 L134 V135 D136 T137 K141 I148 N151 G152 L153 V154 S161 M163 L165 D202 G203 T204 M205 C210 S212 F213 Q216 G235 C236 D237 C239 Q240 L30 L34 T44 E47 R54 T93 N95 D130 L134 V135 D136 T137 K141 I148 N151 G152 L153 V154 S161 M163 L165 D202 G203 T204 M205 C210 S212 F213 Q216 G235 C236 D237 C239 Q240 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s B 2.65 BS03 B12 B 1 L30 L34 T44 R54 T93 N95 Y101 D130 L134 D136 T137 I148 N151 G152 L153 V154 S161 M163 L165 G203 T204 M205 C210 S212 G235 C236 D237 C239 Q240 L30 L34 T44 R54 T93 N95 Y101 D130 L134 D136 T137 I148 N151 G152 L153 V154 S161 M163 L165 G203 T204 M205 C210 S212 G235 C236 D237 C239 Q240 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s C 2.65 BS01 SF4 C 1 K150 N151 I155 C184 C187 R188 R189 C190 C243 P244 Y245 K147 N148 I152 C181 C184 R185 R186 C187 C240 P241 Y242 KLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s C 2.65 BS03 B12 C 1 Y29 L30 L34 T44 R54 T93 N95 D130 L134 D136 T137 K141 I148 N151 G152 L153 V154 S161 M163 L165 D202 G203 T204 M205 C210 S212 Q216 G235 C236 D237 Q240 Y26 L27 L31 T41 R51 T90 N92 D127 L131 D133 T134 K138 I145 N148 G149 L150 V151 S158 M160 L162 D199 G200 T201 M202 C207 S209 Q213 G232 C233 D234 Q237 KLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s E 2.65 BS01 SF4 E 1 G149 K150 I155 C184 C187 R188 C190 C243 P244 Y245 G149 K150 I155 C184 C187 R188 C190 C243 P244 Y245 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d6s E 2.65 BS03 B12 E 1 Y29 L30 L34 T44 E47 R54 T93 N95 D130 L134 D136 T137 K141 I148 N151 G152 L153 V154 S161 M163 L165 G203 T204 M205 C210 S212 C236 C239 Q240 Y29 L30 L34 T44 E47 R54 T93 N95 D130 L134 D136 T137 K141 I148 N151 G152 L153 V154 S161 M163 L165 G203 T204 M205 C210 S212 C236 C239 Q240 MNIKLEIQKMAKEIGISKIGFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLPQQPQKTEFKRGKITPNSWGLDYHYVLQDKLKRLAKGIEKLTENFEYKGMVDTGALVDTAVAKRAGIGFIGKNGLVISKEYGSYMYLGELITNLEIEPDQEVDYGCGDCRRCLDACPTSCLIGDGTMNARRCLSFQTQDKGMMDMEFRKKIKTVIYGCDICQISCPYNRGIDNPLDIDPDLAMPELLPFLELTNKSFKETFGMIAGSWRGKNILQRNAIIALANLHDRNAIVKLMEIIDKNNNPIHTATAIWALGEIVKKPDEGMLDYMRGLSPKDEHSQAEWELVCAKWQI 5d7e A 1.90 BS01 III C 1 F27 H59 T61 F62 G80 W81 G82 G83 P85 D104 F107 L108 F30 H62 T64 F65 G83 W84 G85 G86 P88 D107 F110 L111 P35189 26341557 LGSMVATVKRTIRIKTQQHILPEVPPVENFPVRQWSIEIVLLDDEGKEIPATIFDKVIYHLHPTFANPNRTFTDPPFRIEEQGWGGFPLDISVFLLEKAGERKIPHDLNFLQESYEVEHVIQIPLNKPLLTEELAKSGST 5d8a A 2.40 BS01 III D 1 T33 F34 D37 D75 A116 P118 R178 R181 T33 F34 D37 D75 A116 P118 R158 R161 Q6PN23 TTTTGESADPVTTTVENYGGETQVQRRQHTDVTFIMDRFVKIQNLNPTHVIDLMQTHQHGLVGALLRAATYYFSDLEIVVRHDGNLTWVPNGAPEAALSNTGNPTAYLKAPFTRLALPYTAPHRVLATVYNGTSKAQLPASFNFGAIQATTIHELLVRMKRAELYCPRPLLAVEVSSQDRHKQKIIAPAK 5d8p D 2.35 BS01 FE2 D 1 K6 H10 H107 K6 H10 H107 1.16.3.1 Q9HY79 26368531 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 5d8p D 2.35 BS05 FE2 D 5 E81 E85 E81 E85 1.16.3.1 Q9HY79 26368531 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 5d8p D 2.35 BS06 HEM D 1 I22 N23 F26 Y45 I49 M52 I59 I22 N23 F26 Y45 I49 M52 I59 1.16.3.1 Q9HY79 26368531 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 5d8p G 2.35 BS05 FE2 G 4 D132 E135 D132 E135 1.16.3.1 Q9HY79 26368531 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 5d8q L 2.20 BS01 HEM L 1 I22 F26 Y45 I49 M52 K53 I59 I22 F26 Y45 I49 M52 K53 I59 1.16.3.1 Q9HY79 26368531 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGAPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 5d8r L 2.50 BS01 HEM L 1 L19 I22 F26 Y45 I49 M52 K53 I59 L19 I22 F26 Y45 I49 M52 K53 I59 1.16.3.1 Q9HY79 26368531 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGANTQEMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 5d8s C 2.55 BS01 HEM C 1 L19 I22 F26 Y45 I49 M52 K53 L19 I22 F26 Y45 I49 M52 K53 1.16.3.1 Q9HY79 26368531 MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESIDEMKHADKLIERILFLEGLPNLQDLGKLLIGENTQAMLQCDLNLELKATKDLREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQSHMHE 5d9b A 1.50 BS01 MG A 1 E18 N160 D212 E17 N159 D211 Q95YI4 26360462 GPVVEKIAELGKYTVGEGPHWDHETQTLYFVDTVEKTFHKYVPSQKKYTFCKVDKLVSFIIPLAGSPGRFVVSLEREIAILTWDGVSAAPTSIEAIVNVEPHIKNNRLNDGKADPLGNLWTGTMAIDAGLPIGPVTGSLYHLGADKKVKMHESNIAIANGLAWSNDLKKMYYIDSGKRRVDEYDYDASTLSISNQRPLFTFEKHEVPGYPDGQTIDEEGNLWVAVFQGQRIIKISTQQPEVLLDTVKIPDPQVTSVAFGGPNLDELYVTSAGLQLDDSSFDKSLVNGHVYRVTGLGVKGFAGVKVKL 5dbx A 2.50 BS01 ANP A 1 I81 G82 G84 V89 K104 M150 K151 L153 L211 I17 G18 G20 V25 K40 M86 K87 L89 L147 2.7.11.1 Q9Z1W9 26208601 AVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLAFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTR 5dbx B 2.50 BS01 ANP B 1 I81 G84 A85 V89 A102 K104 M150 K151 L153 L211 I17 G20 A21 V25 A38 K40 M82 K83 L85 L143 2.7.11.1 Q9Z1W9 26208601 AVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLT 5ddj 1 3.50 BS01 III 4 1 S33 F34 D37 F73 D75 A116 P118 K181 R182 S33 F34 D37 F73 D75 A116 P118 K157 R158 Q6PMW3 TTSAGESADPVTATVENYGGETQVQRRQHTDVSFILDRFVKVTPKDQINVLDLMQTPAHTLVGALLRTATYYFADLEVAVKHEGNLTWVPNGAPEAALDNTTNPTAYHKAPLTRLALPYTAPHRVLATVYNGRALPTSFNYGAIKATRVTELLYRMKRAETYCPRPLLAIHPDQARHKQKIVAP 5ddj 1 3.50 BS02 III 4 2 T1 T2 S3 A4 P10 V11 T12 T14 N17 P188 T1 T2 S3 A4 P10 V11 T12 T14 N17 P164 Q6PMW3 TTSAGESADPVTATVENYGGETQVQRRQHTDVSFILDRFVKVTPKDQINVLDLMQTPAHTLVGALLRTATYYFADLEVAVKHEGNLTWVPNGAPEAALDNTTNPTAYHKAPLTRLALPYTAPHRVLATVYNGRALPTSFNYGAIKATRVTELLYRMKRAETYCPRPLLAIHPDQARHKQKIVAP 5ddj 2 3.50 BS02 III 4 3 Y34 G35 Y36 T38 L142 Y26 G27 Y28 T30 L134 Q6PMW3 LLEDRILTTRNGHTTSTTQSSVGVTYGYATAEDFVSGPNTSGLETRVAQAERFFKTHLFDWVTSDPFGRCHLLELPTDHKGVYGYLTDSYAYMRNGWDVEVTAVGNQFNGGCLLVAMVPELCSIQKRELYQLTLFPHQFINPRTNMTAHITVPFVGVNRYDQYKVHKPWTLVVMVVAPLTVNSEGAPQIKVYANIAPTNVHVAGEFPSKE 5det A 1.95 BS01 NUC P 1 F27 S29 K56 F65 E97 F98 A99 K100 A101 N102 T103 K104 M105 F7 S9 K36 F45 E77 F78 A79 K80 A81 N82 T83 K84 M85 Q93062 26347403 EEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLV 5det B 1.95 BS01 NUC Q 1 F27 L54 K56 T58 K60 Q61 V63 F65 E97 F98 A99 K100 A101 N102 T103 K104 M105 F10 L37 K39 T41 K43 Q44 V46 F48 E80 F81 A82 K83 A84 N85 T86 K87 M88 Q93062 26347403 NLEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLV 5df6 A 1.78 BS01 III B 1 R32 S34 K35 S36 T42 T52 H53 I54 Q87 L88 K89 E90 K91 I96 R29 S31 K32 S33 T39 T49 H50 I51 Q84 L85 K86 E87 K88 I93 3.1.3.48 Q06124 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESKSKVTHVMIRCQKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR 5df6 A 1.78 BS02 III C 1 G119 K120 R138 S140 Q141 S142 V148 T168 H169 V170 M171 V181 M202 V203 E204 T205 G116 K117 R135 S137 Q138 S139 V145 T162 H163 V164 M165 V173 M194 V195 E196 T197 3.1.3.48 Q06124 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESKSKVTHVMIRCQKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR 5dm0 A 1.75 BS01 SAH A 1 Q18 F21 D34 G68 G70 D91 S92 S93 N113 A114 H131 C133 L136 F137 Q17 F20 D33 G67 G69 D90 S91 S92 N112 A113 H130 C132 L135 F136 A7Z2A9 25635336 EIETIVRESEANRIQAQTWFSHPEKSKVSFRYDERETSSIRSISIETFLSFYSSKFNREPYSVLDIGCGQGQVIQYLNSRFQKIELTGIDSSAQAISSAKKLGINASFICSNAENIMQYVSKKQDIIFIHLCFGLFKNPIAIVNTLIHLLSDQSCIYIVDLDRNSLGEGLNTAQSREEEAYLKDQYRASLTMEEFKQLLHVVTKEQHGVSFHVGNSFIGGFDETSSQFFSLMRNRNLQDALRTSVGEQLKQSQMPALLHGWIIKNK 5dm0 A 1.75 BS02 5D8 A 1 F21 Y33 D34 T38 L132 G135 L136 D161 L162 Y182 L183 Q186 S190 M255 P256 L258 F20 Y32 D33 T37 L131 G134 L135 D160 L161 Y181 L182 Q185 S189 M254 P255 L257 A7Z2A9 25635336 EIETIVRESEANRIQAQTWFSHPEKSKVSFRYDERETSSIRSISIETFLSFYSSKFNREPYSVLDIGCGQGQVIQYLNSRFQKIELTGIDSSAQAISSAKKLGINASFICSNAENIMQYVSKKQDIIFIHLCFGLFKNPIAIVNTLIHLLSDQSCIYIVDLDRNSLGEGLNTAQSREEEAYLKDQYRASLTMEEFKQLLHVVTKEQHGVSFHVGNSFIGGFDETSSQFFSLMRNRNLQDALRTSVGEQLKQSQMPALLHGWIIKNK 5dm0 B 1.75 BS02 5D8 B 1 F21 Y33 D34 T38 I41 L132 G135 L136 D161 L162 Y182 L183 Q186 S190 F218 M255 P256 L258 F23 Y35 D36 T40 I43 L134 G137 L138 D163 L164 Y184 L185 Q188 S192 F220 M257 P258 L260 A7Z2A9 25635336 AAAEIETIVRESEANRIQAQTWFSHPEKSKVSFRYDERETSSIRSISIETFLSFYSSKFNREPYSVLDIGCGQGQVIQYLNSRFQKIELTGIDSSAQAISSAKKLGINASFICSNAENIMQYVSKKQDIIFIHLCFGLFKNPIAIVNTLIHLLSDQSCIYIVDLDRNSLGEGLNTAQSREEEAYLKDQYRASLTMEEFKQLLHVVTKEQHGVSFHVGNSFIGGFDETSSQFFSLMRNRNLQDALRTSVGEQLKQSQMPALLHGWIIKNKRYT 5dm1 A 1.80 BS01 5D7 A 1 F20 Y32 D33 E36 T37 T40 L130 C131 G133 L134 D159 L160 Y180 I181 Q184 S188 V253 F21 Y33 D34 E37 T38 T41 L131 C132 G134 L135 D160 L161 Y181 I182 Q185 S189 V247 B4ADV2 25635336 GMIQEKIKELEVKRALAQSWFSDPDKRKISSNYDNRETPFTRFLSAETFTSYYQLTFKKTPVSILDIGCGQGQMLEYISKQLPLADLTGIDSSEEAIHCANKLNIKANFICTDIKNFSSHAKIYDVILIHLCFGLFENPIELLEQLLPYLSNESMIYIVDLNRDSIESGLSSVQSKEEELYIYDQYHASLTLSEFEQLLTYITKPREDMMYKIGTSIIGGFSPFSMEFLSLLGNGNLQQTLRQAPDVLLHAWLIKNR 5dm1 A 1.80 BS02 SAH A 1 Q17 F20 R26 D33 R41 G67 G69 I89 D90 S91 T111 D112 I113 H129 C131 L134 F135 Q18 F21 R27 D34 R42 G68 G70 I90 D91 S92 T112 D113 I114 H130 C132 L135 F136 B4ADV2 25635336 GMIQEKIKELEVKRALAQSWFSDPDKRKISSNYDNRETPFTRFLSAETFTSYYQLTFKKTPVSILDIGCGQGQMLEYISKQLPLADLTGIDSSEEAIHCANKLNIKANFICTDIKNFSSHAKIYDVILIHLCFGLFENPIELLEQLLPYLSNESMIYIVDLNRDSIESGLSSVQSKEEELYIYDQYHASLTLSEFEQLLTYITKPREDMMYKIGTSIIGGFSPFSMEFLSLLGNGNLQQTLRQAPDVLLHAWLIKNR 5dm2 A 1.50 BS01 SAH A 1 Q17 F20 R41 G67 D90 S91 S92 T111 D112 I113 H129 C131 L134 F135 Q16 F19 R40 G66 D89 S90 S91 T110 D111 I112 H128 C130 L133 F134 B4ADV2 25635336 IQEKIKELEVKRALAQSWFSDPDKRKISSNYDNRETPFTRFLSAETFTSYYQLTFKKTPVSILDIGCGQGQMLEYISKQLPLADLTGIDSSEEAIHCANKLNIKANFICTDIKNFSSHAKIYDVILIHLCFGLFENPIELLEQLLPYLSNESMIYIVDLNRDSIESGLSSVQSKEEELYIYDQYHASLTLSEFEQLLTYITKPREDMMYKIGTSIIGGFSPFSMEFLSLIGNGNLQQTLRQAPDQYPVLLHAWLIKNR 5dm2 A 1.50 BS02 5D9 A 1 F20 Y32 D33 T37 T40 L130 C131 G133 L134 D159 L160 Y180 I181 Q184 S188 Y247 V253 L254 F19 Y31 D32 T36 T39 L129 C130 G132 L133 D158 L159 Y179 I180 Q183 S187 Y246 V248 L249 B4ADV2 25635336 IQEKIKELEVKRALAQSWFSDPDKRKISSNYDNRETPFTRFLSAETFTSYYQLTFKKTPVSILDIGCGQGQMLEYISKQLPLADLTGIDSSEEAIHCANKLNIKANFICTDIKNFSSHAKIYDVILIHLCFGLFENPIELLEQLLPYLSNESMIYIVDLNRDSIESGLSSVQSKEEELYIYDQYHASLTLSEFEQLLTYITKPREDMMYKIGTSIIGGFSPFSMEFLSLIGNGNLQQTLRQAPDQYPVLLHAWLIKNR 5dm4 A 1.75 BS02 5DA A 1 F20 Y32 D33 T37 T40 L130 C131 G133 L134 D159 L160 Y180 I181 Q184 S188 Q246 Y247 L249 F19 Y31 D32 T36 T39 L129 C130 G132 L133 D158 L159 Y179 I180 Q183 S187 Q245 Y246 L248 B4ADV2 25635336 IQEKIKELEVKRALAQSWFSDPDKRKISSNYDNRETPFTRFLSAETFTSYYQLTFKKTPVSILDIGCGQGQMLEYISKQLPLADLTGIDSSEEAIHCANKLNIKANFICTDIKNFSSHAKIYDVILIHLCFGLFENPIELLEQLLPYLSNESMIYIVDLNRDSIESGLSSVQSKEEELYIYDQYHASLTLSEFEQLLTYITKPREDMMYKIGTSIIGGFSPFSMEFLSLIGNGNLQQTLRQAPDQYVLLHAWLIKNR 5dpk A 2.20 BS01 NUC B 1 Q48 T49 R50 G85 L86 G87 Y88 Y89 R201 G260 L261 L262 H305 F307 S308 H309 P345 V346 Q42 T43 R44 G79 L80 G81 Y82 Y83 R195 G254 L255 L256 H294 F296 S297 H298 P334 V335 3.2.2.- P83847 RFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKPSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGEQELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 5dpk A 2.20 BS02 NUC C 1 L46 Q47 Q48 T49 R50 V51 G122 G124 P125 Y126 T127 D144 G145 N146 R149 I191 P200 R201 L40 Q41 Q42 T43 R44 V45 G116 G118 P119 Y120 T121 D138 G139 N140 R143 I185 P194 R195 3.2.2.- P83847 RFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKPSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGEQELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 5dpk A 2.20 BS03 SF4 A 1 R153 L154 C198 P203 C205 C208 Q211 C214 A222 R147 L148 C192 P197 C199 C202 Q205 C208 A216 3.2.2.- P83847 RFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKPSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGEQELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 5dpk A 2.20 BS05 CA A 2 D257 T259 D251 T253 3.2.2.- P83847 RFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKPSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGEQELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS