2n2k A BS01 MTN A 1 T22 C25 T22 C25 P0CG48 26090905 MQIFVKTLTGKTITLEVEPSDTIECVKAKIQDKEGIPPDQQRLIFAGCQLEDGRTLSDYNIQKESTLHLVLRLRGG 2n2k A BS02 MTN A 2 C48 Q49 C48 Q49 P0CG48 26090905 MQIFVKTLTGKTITLEVEPSDTIECVKAKIQDKEGIPPDQQRLIFAGCQLEDGRTLSDYNIQKESTLHLVLRLRGG 3wwx A 1.49 BS01 DIA A 1 V154 F155 S246 L248 G337 I338 H339 S341 S342 D362 V117 F118 S209 L211 G298 I299 H300 S302 S303 D323 E2RVJ1 PDHAATQQALEAAVADGVPGAVAQARDGRDRWTGTAGERGGDDRYRVGSITKTFTATVLLQLQAEGRIDLDDPVEKWLPGVVRGNGHDGRKITVRQLLNHTSGIYSYTEDPAFQAKVFGPGFLEHRYDTWTPKQLVAVAMAHEPDFTPGASWNYSNTNFVLAGMVIEKVTGRPYGKAVENRIIKPLKLRATTVPGTRSAMPEPSSPAYSKLSRNAPVHDVSTLNPSIAGAAGEMISDSRDLQTFYRALLQGRLLPKSALNEMTTTVQISPEYPNVGYGLGLMKDKLSCGVEVWGHGGGIHGSSSLAQVTRDGGHSLAGNFNADWAGDSQKVIEAEFCGTA 4d6y A 1.70 BS01 BEF A 1 D53 I54 W55 S83 G84 H85 K105 D50 I51 W52 S80 G81 H82 K102 Q2YPW6 26113057 DILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSK 4d6y A 1.70 BS02 MG A 1 D10 D53 W55 D7 D50 W52 Q2YPW6 26113057 DILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSK 4pa0 A 2.25 BS01 2OW A 1 A91 M92 L96 S118 F121 M493 V698 G701 I702 C705 P710 N711 R712 L770 A90 M91 L95 S117 F120 M483 V669 G672 I673 C676 P681 N682 R683 L741 P42212 GDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRTQAAEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFVQCFSRYPDHMKRHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKNGIKANFKTRHVQLADHYQQNTPIGNGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLEFVTAA 4pa0 B 2.25 BS01 2OW B 1 A91 M92 L96 S118 F121 V698 G701 I702 C705 P710 N711 R712 A90 M91 L95 S117 F120 V666 G669 I670 C673 P678 N679 R680 P42212 GDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAASRKGAEKLLSSNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRTPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFVQCFSRYPDHMKRHDFFKSAMPEGYVQERTIFFGNYKTRAEVKTLVNRIELKEYNYNSHNVYIMADKQKNGIKANFKTRHNIELADHYQQNTPILLPDNHYLSTQSALSKRDHMVLLEFVTAAGI 4qis A 1.91 BS01 FMN A 1 A18 P19 M20 L21 V23 N69 F71 H133 Q176 A180 G181 G182 G217 G218 Q237 M238 G239 T240 Y254 W325 A15 P16 M17 L18 V20 N66 F68 H130 Q173 A177 G178 G179 G214 G215 Q234 M235 G236 T237 Y251 W322 1.7.3.1 RFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPVRLKNIYLSFLEDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGHRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRAARTALTVTMSGRSARGLPNRMFFDAAAPGVPPLPDYPFVYDATKALQTAALARGNHDFAAQWAGQGAALARELPAAELLRTLVEEL 4qit A 1.40 BS02 NIE A 1 F71 G182 S183 W325 F71 G182 S183 W325 1.7.3.1 MTDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPVRLKNIYLSFLEDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGSRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRAARTALTVTMSGRSARGLPNRMFFDAAAPGVPPLPDYPFVYDATKALQTAALARGNHDFAAQWAGQGAALARELPAAELLRTLVEELR 4qiu A 1.40 BS01 FMN A 1 A18 P19 M20 L21 N69 F71 H133 Q176 A180 G181 G217 G218 Q237 M238 G239 T240 Y254 W325 A17 P18 M19 L20 N68 F70 H132 Q175 A179 G180 G216 G217 Q236 M237 G238 T239 Y253 W324 1.7.3.1 TDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPVRLKNIYLSFLEDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGCRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRAARTALTVTMSGRSARGLPNRMFFDAAAPGVPPLPDYPFVYDATKALQTAALARGNHDFAAQWAGQGAALARELPAAELLRTLVEELRG 4qiu A 1.40 BS02 N1P A 1 L21 Y109 C183 W325 L20 Y108 C182 W324 1.7.3.1 TDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPVRLKNIYLSFLEDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGCRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRAARTALTVTMSGRSARGLPNRMFFDAAAPGVPPLPDYPFVYDATKALQTAALARGNHDFAAQWAGQGAALARELPAAELLRTLVEELRG 4qiu B 1.40 BS02 N1P B 1 L21 F71 Y109 C183 Y303 W325 L20 F70 Y108 C182 Y302 W324 1.7.3.1 TDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPVRLKNIYLSFLEDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGCRGVFEPERGDAAIGTLALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALKGPRAARTALTVTMSGRSARGLPNRMFFDAAAPGVPPLPDYPFVYDATKALQTAALARGNHDFAAQWAGQGAALARELPAAELLRTLVEELRG 4qsy A 2.10 BS01 III B 1 V14 E17 R32 S34 K35 S36 T42 T52 H53 I54 K55 L65 G67 G68 Q87 L88 K89 E90 K91 I96 V10 E13 R28 S30 K31 S32 T38 T48 H49 I50 K51 L61 G63 G64 Q83 L84 K85 E86 K87 I92 3.1.3.48 Q06124 RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNC 4qsz A 2.86 BS01 GLC A 1 D-357 K-356 E-260 E-218 Y-216 F-215 W-141 D14 K15 E111 E153 Y155 F156 W230 P0C872 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALAAAQTNAAAEFAEAALEAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSLSYLRATVGSTEVSVAVTPDGYADAVRGDRFVMPAERRLPISHVLDVLEGRAQHPGVLYVQKCSNLPTELPQLLSDIESHVPWASESLGKMPDAVNFWLGDASAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVVDEEAMEKVPWIPLDPLAPDLTQYPSYSQAQALHCTVRAGEMLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDTLTRATGLD 4qsz A 2.86 BS02 GLC A 2 W-309 A-308 D-306 E-218 Y-216 W-31 W62 A63 D65 E153 Y155 W340 P0C872 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALAAAQTNAAAEFAEAALEAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSLSYLRATVGSTEVSVAVTPDGYADAVRGDRFVMPAERRLPISHVLDVLEGRAQHPGVLYVQKCSNLPTELPQLLSDIESHVPWASESLGKMPDAVNFWLGDASAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVVDEEAMEKVPWIPLDPLAPDLTQYPSYSQAQALHCTVRAGEMLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDTLTRATGLD 4qsz B 2.86 BS01 GLC B 1 N-359 D-357 K-356 A-308 E-260 E-218 Y-216 F-215 W-141 N7 D9 K10 A58 E106 E148 Y150 F151 W225 P0C872 KLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALAAAQTNAAAEFAEAALEAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSLSYLRATVGSTEVSVAVTPDGYADAVRGDRFVMPAERRLPISHVLDVLEGRAQHPGVLYVQKQCSNLPTELPQLLSDIESHVPWASESLGKMPDAVNFWLGDASAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVVDEEAMEKVPWIPLDPLAPDLTQYPSYSQAQALHCTVRAGEMLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDTLTRATGLD 4qsz B 2.86 BS02 GLC B 2 W-309 A-308 D-306 E-218 P-217 Y-216 M-41 W-31 W57 A58 D60 E148 P149 Y150 M325 W335 P0C872 KLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALAAAQTNAAAEFAEAALEAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSLSYLRATVGSTEVSVAVTPDGYADAVRGDRFVMPAERRLPISHVLDVLEGRAQHPGVLYVQKQCSNLPTELPQLLSDIESHVPWASESLGKMPDAVNFWLGDASAVTSLHKDHYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVVDEEAMEKVPWIPLDPLAPDLTQYPSYSQAQALHCTVRAGEMLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDTLTRATGLD 4s3q A 2.10 BS01 MAL A 1 Y201 W413 H547 D548 N648 P650 G651 Y192 W404 H538 D539 N639 P641 G642 2.4.1.25 P15977 ESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQTPVPNVMVYTSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWRRKLSATLESMFADDGVNKLLKDLDRRRRSAH 4s3r A 2.10 BS01 7SA A 1 S199 Y201 S202 V377 E381 D404 I405 L406 Q411 N412 W413 G414 R446 D448 H449 M451 E496 L498 G499 F522 H547 D548 N648 P650 G651 T652 S189 Y191 S192 V367 E371 D394 I395 L396 Q401 N402 W403 G404 R436 D438 H439 M441 E486 L488 G489 F512 H537 D538 N638 P640 G641 T642 2.4.1.25 P15977 ESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHTPVPNVMVYTSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWRRKLSATLESMFADDGVNKLLKDLDRRRRSA 4ts3 A 2.30 BS01 FMC A 1 M64 R87 S90 C91 G92 F159 V178 E179 M180 E181 S203 D204 M64 R87 S90 C91 G92 F159 V178 E179 M180 E181 S203 D204 2.4.2.1 ATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDK 4ts3 F 2.30 BS01 FMC F 1 M64 S90 C91 G92 F159 V178 E179 M180 E181 S203 D204 M64 S90 C91 G92 F159 V178 E179 M180 E181 S203 D204 2.4.2.1 ATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDK 4ts9 B 1.77 BS01 FMC B 1 M64 R87 S90 C91 G92 F159 V178 E179 M180 E181 D204 I206 M64 R87 S90 C91 G92 F159 V178 E179 M180 E181 D204 I206 2.4.2.1 ATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVASCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDK 4tta C 2.00 BS01 FMC C 1 M64 R87 S90 C91 G92 F159 V178 E179 M180 E181 M64 R87 S90 C91 G92 F159 V178 E179 M180 E181 2.4.2.1 ATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSAHTTFNDMIKIALESVLLGDK 4tu5 X 2.16 BS01 NDP X 1 V6 A7 I14 G15 N18 Q19 L20 G43 R44 K45 T46 L62 T63 S64 H77 I79 F92 G93 G94 Q95 T96 E100 T121 V6 A7 I14 G15 N18 Q19 L20 G43 R44 K45 T46 L62 T63 S64 H77 I79 F92 G93 G94 Q95 T96 E100 T121 1.5.1.3 TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK 4tu5 X 2.16 BS02 06W X 1 L5 V6 A7 L20 D27 L28 V31 M42 T46 I50 K52 L54 F92 T111 L5 V6 A7 L20 D27 L28 V31 M42 T46 I50 K52 L54 F92 T111 1.5.1.3 TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK 4tvb A 1.69 BS01 NAI A 1 I17 G20 S21 I22 D45 P46 S47 A65 V66 L91 S92 V93 T95 T114 V115 E117 A161 N162 P163 W229 S230 G233 I350 V400 I15 G18 S19 I20 D43 P44 S45 A63 V64 L89 S90 V91 T93 T112 V113 E115 A159 N160 P161 W227 S228 G231 I348 V398 2.5.1.44 O32323 DWPVYHRIDGPIVMIGFGSIGRGTLPLIERHFAFDRSKLVVIDPSDEARKLAEARGVRFIQQAVTRDNYRELLVPLLTAGPGQGFCVNLSVDTSSLDIMELARENGALYIDTVVEPWLGFYFDPDLKPEARSNYALRETVLAARRNKPGGTTAVSCCGANPGMVSWFVKQALVNLAADLGVTGEEPTTREEWARLAMDLGVKGIHIAERDTQRASFPKPFDVFVNTWSVEGFVSEGLQPAELGWGTFERWMPDNARGHDSGCGAGIYLLQPGANTRVRSWTPTAMAQYGFLVTHNESISIADFLTVRDAAGQAVYRPTCHYAYHPCNDAVLSLHEMFGSGKRQSDWRILDETEIVDGIDELGVLLYGHGKNAYWYGSQLSIEETRRIAPDQNATGLQVSSAVLAGMVWALENPNAGIVEADDLDFRRCLEVQTPYLGPVVGVYTDWTPLAGRPGLFPEDIDTSDPWQFRNVLVRD 4tvb A 1.69 BS02 37Z A 1 V115 N162 P163 E210 W229 G233 E237 H296 Y323 Y325 D361 L363 T396 V113 N160 P161 E208 W227 G231 E235 H294 Y321 Y323 D359 L361 T394 2.5.1.44 O32323 DWPVYHRIDGPIVMIGFGSIGRGTLPLIERHFAFDRSKLVVIDPSDEARKLAEARGVRFIQQAVTRDNYRELLVPLLTAGPGQGFCVNLSVDTSSLDIMELARENGALYIDTVVEPWLGFYFDPDLKPEARSNYALRETVLAARRNKPGGTTAVSCCGANPGMVSWFVKQALVNLAADLGVTGEEPTTREEWARLAMDLGVKGIHIAERDTQRASFPKPFDVFVNTWSVEGFVSEGLQPAELGWGTFERWMPDNARGHDSGCGAGIYLLQPGANTRVRSWTPTAMAQYGFLVTHNESISIADFLTVRDAAGQAVYRPTCHYAYHPCNDAVLSLHEMFGSGKRQSDWRILDETEIVDGIDELGVLLYGHGKNAYWYGSQLSIEETRRIAPDQNATGLQVSSAVLAGMVWALENPNAGIVEADDLDFRRCLEVQTPYLGPVVGVYTDWTPLAGRPGLFPEDIDTSDPWQFRNVLVRD 4tvb A 1.69 BS03 1PS A 1 S47 D48 E49 D347 W348 S45 D46 E47 D345 W346 2.5.1.44 O32323 DWPVYHRIDGPIVMIGFGSIGRGTLPLIERHFAFDRSKLVVIDPSDEARKLAEARGVRFIQQAVTRDNYRELLVPLLTAGPGQGFCVNLSVDTSSLDIMELARENGALYIDTVVEPWLGFYFDPDLKPEARSNYALRETVLAARRNKPGGTTAVSCCGANPGMVSWFVKQALVNLAADLGVTGEEPTTREEWARLAMDLGVKGIHIAERDTQRASFPKPFDVFVNTWSVEGFVSEGLQPAELGWGTFERWMPDNARGHDSGCGAGIYLLQPGANTRVRSWTPTAMAQYGFLVTHNESISIADFLTVRDAAGQAVYRPTCHYAYHPCNDAVLSLHEMFGSGKRQSDWRILDETEIVDGIDELGVLLYGHGKNAYWYGSQLSIEETRRIAPDQNATGLQVSSAVLAGMVWALENPNAGIVEADDLDFRRCLEVQTPYLGPVVGVYTDWTPLAGRPGLFPEDIDTSDPWQFRNVLVRD 4tvb B 1.69 BS01 NAD B 1 I17 F19 G20 S21 I22 R24 D45 P46 S47 A65 V66 L91 S92 V93 T95 T114 V115 E117 G160 A161 N162 P163 W229 S230 G233 I350 V400 I15 F17 G18 S19 I20 R22 D43 P44 S45 A63 V64 L89 S90 V91 T93 T112 V113 E115 G158 A159 N160 P161 W227 S228 G231 I348 V398 2.5.1.44 O32323 DWPVYHRIDGPIVMIGFGSIGRGTLPLIERHFAFDRSKLVVIDPSDEARKLAEARGVRFIQQAVTRDNYRELLVPLLTAGPGQGFCVNLSVDTSSLDIMELARENGALYIDTVVEPWLGFYFDPDLKPEARSNYALRETVLAARRNKPGGTTAVSCCGANPGMVSWFVKQALVNLAADLGVTGEEPTTREEWARLAMDLGVKGIHIAERDTQRASFPKPFDVFVNTWSVEGFVSEGLQPAELGWGTFERWMPDNARGHDSGCGAGIYLLQPGANTRVRSWTPTAMAQYGFLVTHNESISIADFLTVRDAAGQAVYRPTCHYAYHPCNDAVLSLHEMFGSGKRQSDWRILDETEIVDGIDELGVLLYGHGKNAYWYGSQLSIEETRRIAPDQNATGLQVSSAVLAGMVWALENPNAGIVEADDLDFRRCLEVQTPYLGPVVGVYTDWTPLAGRPGLFPEDIDTSDPWQFRNVLVRD 4tvb B 1.69 BS02 PUT B 1 A161 N162 P163 E210 W229 E237 H296 Y323 Y325 D361 L363 T396 A159 N160 P161 E208 W227 E235 H294 Y321 Y323 D359 L361 T394 2.5.1.44 O32323 DWPVYHRIDGPIVMIGFGSIGRGTLPLIERHFAFDRSKLVVIDPSDEARKLAEARGVRFIQQAVTRDNYRELLVPLLTAGPGQGFCVNLSVDTSSLDIMELARENGALYIDTVVEPWLGFYFDPDLKPEARSNYALRETVLAARRNKPGGTTAVSCCGANPGMVSWFVKQALVNLAADLGVTGEEPTTREEWARLAMDLGVKGIHIAERDTQRASFPKPFDVFVNTWSVEGFVSEGLQPAELGWGTFERWMPDNARGHDSGCGAGIYLLQPGANTRVRSWTPTAMAQYGFLVTHNESISIADFLTVRDAAGQAVYRPTCHYAYHPCNDAVLSLHEMFGSGKRQSDWRILDETEIVDGIDELGVLLYGHGKNAYWYGSQLSIEETRRIAPDQNATGLQVSSAVLAGMVWALENPNAGIVEADDLDFRRCLEVQTPYLGPVVGVYTDWTPLAGRPGLFPEDIDTSDPWQFRNVLVRD 4tvj A 2.10 BS01 09L A 1 E335 H428 G429 L443 R444 A446 Y455 G460 I461 Y462 F463 S470 Y473 E113 H206 G207 L221 R222 A224 Y233 G238 I239 Y240 F241 S248 Y251 2.4.2.30 Q9UGN5 DLGTENLYFQSMDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAHPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNF 4twz A 2.80 BS01 MG A 1 E285 A287 G288 W290 E280 A282 G283 W285 P0A7G6 25561575 KQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPN 4u6a A 2.37 BS02 3DN A 1 H1184 G1185 P1187 F1188 A1202 Y1203 I1204 Y1213 F1214 A1215 K1220 S1221 Y1224 I1228 E1291 H80 G81 P83 F84 A98 Y99 I100 Y109 F110 A111 K116 S117 Y120 I124 E182 2.4.2.30 O95271 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPAYAEYVIYRGEQAYPEYLITYQIMKPE 4u9r A 2.17 BS01 CD A 1 D42 C44 H105 E146 D22 C24 H85 E126 Q1LAJ7 NATEKLRLDIPVLLPGLPDSSDPCVERLLSELRGKEGVEAAHIKTANVDSDSQICVHYDPAAISLARIRELVTSTGAVISSRFGHVLWQLKGVWHERRARTVASQLRALPGVIEAEVSASGIARVEFDNDRISAAGIEQALSKRGLA 4u9r A 2.17 BS02 CD A 2 H62 C75 H77 H42 C55 H57 Q1LAJ7 NATEKLRLDIPVLLPGLPDSSDPCVERLLSELRGKEGVEAAHIKTANVDSDSQICVHYDPAAISLARIRELVTSTGAVISSRFGHVLWQLKGVWHERRARTVASQLRALPGVIEAEVSASGIARVEFDNDRISAAGIEQALSKRGLA 4u9r A 2.17 BS03 TCE A 1 K25 R27 H62 K64 H77 K5 R7 H42 K44 H57 Q1LAJ7 NATEKLRLDIPVLLPGLPDSSDPCVERLLSELRGKEGVEAAHIKTANVDSDSQICVHYDPAAISLARIRELVTSTGAVISSRFGHVLWQLKGVWHERRARTVASQLRALPGVIEAEVSASGIARVEFDNDRISAAGIEQALSKRGLA 4ufc A 2.81 BS01 CA A 1 S42 E62 S343 Q349 I356 S22 E42 S323 Q329 I336 A7M011 26112186 DLKLWYSQPAQNWSEALPIGNSRLGAMVYGGIEREELQLNEETFWAGSPYNNNNPNAVHVLPVVRKLIFEGRNKEAQRLIDANFLTQQHGMSYLTLGSLYLEFPEHQNGSGFYRDLNLENATTTTRYQVDDVTYTRTTFASFTDNVIIMHIKASKANALNFTIAYNCPLVHKVNVQNDQLTVTCQGKEQEGLKAALRAECQIQVKTNGTLRPAGNTLQINEGTEATLYISAATNYVNYQDVSADESHRTSEYLKRAMQIPYEKALKNHIAYYKKQFDRVRLTLPAGKASQLETPKRIENFGNGEDMAMAALLFHYGRYLLISSSQPGGQPANLQGIWNNSTHAPWDSKYTININTEMNYWPAEVTNLSETHSPLFSMLKDLSVTGAETARTMYDCRGWVAHHNTDLWRICGVVDFAAAGMWPSGGAWLAQHIWQHYLFTGNKEFLKEYYPILKGTAQFYMDFLVEHPVYKWLVVSPSVSPEHGPITAGCTMDNQIAFDALHNTLLASYIAGEAPSFQDSLKQTLEKLPPMQIGKHNQLQEWLEDIDNPKDEHRHISHLYGLYPSNQISPYSNPELFQAARNTLLQRGDKATGWSIGWKVNFWARMLDGNHAFQIIKNMIQLLPNDHLAKEYPNGRTYPNMLDAHPPFQIDGNFGYTAGVAEMLLQSHDGAVHLLPALPDAWEEGSVKGLVARGNFTVDMDWKNNVLNKAIIRSNIGSTLRIRSYVPLKGKGLKQVNGKECSNRLFATTPIKQPLVAKGVSAQSPKLQKVYEYDIETKAGKTYIVNTI 4ufc A 2.81 BS02 GIV A 1 W365 T370 N372 N374 E501 R573 H574 W613 H664 W345 T350 N352 N354 E481 R553 H554 W593 H644 A7M011 26112186 DLKLWYSQPAQNWSEALPIGNSRLGAMVYGGIEREELQLNEETFWAGSPYNNNNPNAVHVLPVVRKLIFEGRNKEAQRLIDANFLTQQHGMSYLTLGSLYLEFPEHQNGSGFYRDLNLENATTTTRYQVDDVTYTRTTFASFTDNVIIMHIKASKANALNFTIAYNCPLVHKVNVQNDQLTVTCQGKEQEGLKAALRAECQIQVKTNGTLRPAGNTLQINEGTEATLYISAATNYVNYQDVSADESHRTSEYLKRAMQIPYEKALKNHIAYYKKQFDRVRLTLPAGKASQLETPKRIENFGNGEDMAMAALLFHYGRYLLISSSQPGGQPANLQGIWNNSTHAPWDSKYTININTEMNYWPAEVTNLSETHSPLFSMLKDLSVTGAETARTMYDCRGWVAHHNTDLWRICGVVDFAAAGMWPSGGAWLAQHIWQHYLFTGNKEFLKEYYPILKGTAQFYMDFLVEHPVYKWLVVSPSVSPEHGPITAGCTMDNQIAFDALHNTLLASYIAGEAPSFQDSLKQTLEKLPPMQIGKHNQLQEWLEDIDNPKDEHRHISHLYGLYPSNQISPYSNPELFQAARNTLLQRGDKATGWSIGWKVNFWARMLDGNHAFQIIKNMIQLLPNDHLAKEYPNGRTYPNMLDAHPPFQIDGNFGYTAGVAEMLLQSHDGAVHLLPALPDAWEEGSVKGLVARGNFTVDMDWKNNVLNKAIIRSNIGSTLRIRSYVPLKGKGLKQVNGKECSNRLFATTPIKQPLVAKGVSAQSPKLQKVYEYDIETKAGKTYIVNTI 4ufc B 2.81 BS01 CA B 1 E702 E703 E683 E684 A7M011 26112186 QDLKLWYSQPAQNWSEALPIGNSRLGAMVYGGIEREELQLNEETFWAGSPYNNNNPNAVHVLPVVRKLIFEGRNKEAQRLIDANFLTQQHGMSYLTLGSLYLEFPEHQNGSGFYRDLNLENATTTTRYQVDDVTYTRTTFASFTDNVIIMHIKASKANALNFTIAYNCPLVHKVNVQNDQLTVTCQGKEQEGLKAALRAECQIQVKTNGTLRPAGNTLQINEGTEATLYISAATNYVNYQDVSADESHRTSEYLKRAMQIPYEKALKNHIAYYKKQFDRVRLTLPAGKASQLETPKRIENFGNGEDMAMAALLFHYGRYLLISSSQPGGQPANLQGIWNNSTHAPWDSKYTININTEMNYWPAEVTNLSETHSPLFSMLKDLSVTGAETARTMYDCRGWVAHHNTDLWRICGVVDFAAAGMWPSGGAWLAQHIWQHYLFTGNKEFLKEYYPILKGTAQFYMDFLVEHPVYKWLVVSPSVSPEHGPITAGCTMDNQIAFDALHNTLLASYIAGEAPSFQDSLKQTLEKLPPMQIGKHNQLQEWLEDIDNPKDEHRHISHLYGLYPSNQISPYSNPELFQAARNTLLQRGDKATGWSIGWKVNFWARMLDGNHAFQIIKNMIQLLPNDHLAKEYPNGRTYPNMLDAHPPFQIDGNFGYTAGVAEMLLQSHDGAVHLLPALPDAWEEGSVKGLVARGNFTVDMDWKNNVLNKAIIRSNIGSTLRIRSYVPLKGKGLKQVNGKECSNRLFATTPIKQPLVAKGVSAQSPKLQKVYEYDIETKAGKTYIVNTI 4ufc B 2.81 BS02 CA B 2 S42 E62 S343 S344 Q349 I356 S23 E43 S324 S325 Q330 I337 A7M011 26112186 QDLKLWYSQPAQNWSEALPIGNSRLGAMVYGGIEREELQLNEETFWAGSPYNNNNPNAVHVLPVVRKLIFEGRNKEAQRLIDANFLTQQHGMSYLTLGSLYLEFPEHQNGSGFYRDLNLENATTTTRYQVDDVTYTRTTFASFTDNVIIMHIKASKANALNFTIAYNCPLVHKVNVQNDQLTVTCQGKEQEGLKAALRAECQIQVKTNGTLRPAGNTLQINEGTEATLYISAATNYVNYQDVSADESHRTSEYLKRAMQIPYEKALKNHIAYYKKQFDRVRLTLPAGKASQLETPKRIENFGNGEDMAMAALLFHYGRYLLISSSQPGGQPANLQGIWNNSTHAPWDSKYTININTEMNYWPAEVTNLSETHSPLFSMLKDLSVTGAETARTMYDCRGWVAHHNTDLWRICGVVDFAAAGMWPSGGAWLAQHIWQHYLFTGNKEFLKEYYPILKGTAQFYMDFLVEHPVYKWLVVSPSVSPEHGPITAGCTMDNQIAFDALHNTLLASYIAGEAPSFQDSLKQTLEKLPPMQIGKHNQLQEWLEDIDNPKDEHRHISHLYGLYPSNQISPYSNPELFQAARNTLLQRGDKATGWSIGWKVNFWARMLDGNHAFQIIKNMIQLLPNDHLAKEYPNGRTYPNMLDAHPPFQIDGNFGYTAGVAEMLLQSHDGAVHLLPALPDAWEEGSVKGLVARGNFTVDMDWKNNVLNKAIIRSNIGSTLRIRSYVPLKGKGLKQVNGKECSNRLFATTPIKQPLVAKGVSAQSPKLQKVYEYDIETKAGKTYIVNTI 4ure B 1.40 BS01 1PS B 1 N15 G16 I17 G18 N89 G91 S141 Y155 P185 A186 T190 N15 G16 I17 G18 N89 G91 S141 Y155 P185 A186 T190 1.1.1.311 Q5P8S7 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR 4urf A 1.10 BS01 NAD A 1 G12 G14 N15 G16 I17 D36 I37 W41 A61 D62 T63 N89 A90 G91 I113 I140 S141 Y155 K159 P185 A186 I188 T190 G12 G14 N15 G16 I17 D36 I37 W41 A61 D62 T63 N89 A90 G91 I113 I140 S141 Y155 K159 P185 A186 I188 T190 1.1.1.311 Q5P8S7 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR 4urf A 1.10 BS02 1PS A 1 I92 S93 G94 R109 I92 S93 G94 R109 1.1.1.311 Q5P8S7 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR 4urf A 1.10 BS03 1PS A 2 E95 T97 E101 T103 Q106 E95 T97 E101 T103 Q106 1.1.1.311 Q5P8S7 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR 4urf A 1.10 BS04 MG A 1 S237 Y238 S237 Y238 1.1.1.311 Q5P8S7 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR 4urf A 1.10 BS05 1PS B 1 G174 S175 G177 G174 S175 G177 1.1.1.311 Q5P8S7 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR 4urf B 1.10 BS02 1PS B 1 L210 R211 R212 L210 R211 R212 1.1.1.311 Q5P8S7 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR 4urf B 1.10 BS03 BCT B 1 I92 G94 R109 I92 G94 R109 1.1.1.311 Q5P8S7 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR 4urf B 1.10 BS04 BCT B 2 R179 S228 D229 R179 S228 D229 1.1.1.311 Q5P8S7 MLLEGKTALVTGAGNGIGRTIALTYAAEGANVVVSDISDEWGRETLALIEGKGGKAVFQHADTAHPEDHDELIAAAKRAFGRLDIACNNAGISGEFTPTAETTDAQWQRVIGINLSGVFYGVRAQIRAMLETGGGAIVNISSIAGQIGIEGITPYTAAKHGVVGLTKTVAWEYGSKGIRINSVGPAFINTTLVQNVPLETRRQLEQMHALRRLGETEEVANLVAWLSSDKASFVTGSYYAVDGGYLAR 4uuh A 2.52 BS02 T40 A 1 H1184 G1185 P1187 F1188 H1201 A1202 Y1203 Y1213 F1214 A1215 K1220 S1221 Y1224 I1228 E1291 H80 G81 P83 F84 H97 A98 Y99 Y109 F110 A111 K116 S117 Y120 I124 E181 2.4.2.30 O95271 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPYAEYVIYRGEQAYPEYLITYQIMKPE 4uw1 A 3.37 BS02 92R A 1 H1184 G1185 Y1203 Y1213 A1215 Y1224 I1228 E1291 H80 G81 Y99 Y109 A111 Y120 I124 E187 2.4.2.30 O95271 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKP 4uw1 B 3.37 BS02 92R B 1 H1184 G1185 H1201 Y1203 Y1213 F1214 A1215 K1220 S1221 Y1224 E1291 H80 G81 H97 Y99 Y109 F110 A111 K116 S117 Y120 E187 2.4.2.30 O95271 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKP 4uw1 C 3.37 BS02 92R C 1 H1184 G1185 S1186 A1202 Y1203 Y1213 F1214 A1215 S1221 Y1224 E1291 H77 G78 S79 A95 Y96 Y104 F105 A106 S112 Y115 E182 2.4.2.30 O95271 GTILLDLAPEDKEYQSVEEEMQSTIREHRNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYGGFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPE 4uw1 D 3.37 BS02 92R D 1 H1184 G1185 Y1203 Y1213 F1214 A1215 Y1224 I1228 E1291 H80 G81 Y99 Y109 F110 A111 Y120 I124 E187 2.4.2.30 O95271 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEA 4uw1 E 3.37 BS02 92R E 1 H1184 G1185 S1186 F1188 H1201 Y1203 Y1213 F1214 A1215 K1220 S1221 Y1224 E1291 H80 G81 S82 F84 H97 Y99 Y109 F110 A111 K116 S117 Y120 E184 2.4.2.30 O95271 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSLAYAEYVIYRGEQAYPEYLITYQIMKPE 4uw1 G 3.37 BS02 92R G 1 H1184 G1185 S1186 F1188 Y1203 Y1213 A1215 S1221 Y1224 E1291 H80 G81 S82 F84 Y99 Y109 A111 S117 Y120 E187 2.4.2.30 O95271 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKP 4uw1 H 3.37 BS02 92R H 1 H1184 G1185 H1201 Y1203 Y1213 A1215 S1221 Y1224 I1228 E1291 H80 G81 H97 Y99 Y109 A111 S117 Y120 I124 E187 2.4.2.30 O95271 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPE 4wgk A 2.58 BS01 ZN A 1 H194 H303 E540 Y579 H95 H204 E441 Y480 3.5.1.23 Q9NR71 SGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSIDIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQTFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGPFVAAFASSNLGDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIAKGPGQDMFDSTQIIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDVTVWLNSTHASKTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHKPKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQAEFASHGMQNMTVVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRNLAKAIATDTVANLSRGPEPPFFKQIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNRKQPAVILSFEGTSPAFEVVTI 4wgk A 2.58 BS02 CA A 1 L134 N711 D712 A713 S714 T717 L35 N605 D606 A607 S608 T611 3.5.1.23 Q9NR71 SGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSIDIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQTFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGPFVAAFASSNLGDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIAKGPGQDMFDSTQIIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDVTVWLNSTHASKTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHKPKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQAEFASHGMQNMTVVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRNLAKAIATDTVANLSRGPEPPFFKQIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNRKQPAVILSFEGTSPAFEVVTI 4wgk A 2.58 BS03 PO4 A 1 G122 M162 H194 H196 H303 E540 Y579 Y591 G23 M63 H95 H97 H204 E441 Y480 Y492 3.5.1.23 Q9NR71 SGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSIDIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQTFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGPFVAAFASSNLGDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIAKGPGQDMFDSTQIIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDVTVWLNSTHASKTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHKPKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQAEFASHGMQNMTVVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRNLAKAIATDTVANLSRGPEPPFFKQIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNRKQPAVILSFEGTSPAFEVVTI 4wgk B 2.58 BS02 CA B 1 L134 N711 D712 S714 T717 R718 L36 N609 D610 S612 T615 R616 3.5.1.23 Q9NR71 FSGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSIDIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQTFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGPFVAAFASSNLGDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIAKGPGQDMFDSTQIIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDVTVWLNSTHASKTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHKPKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQAEFASHGMQNMTVVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRNLAKAIATDTVANLSRGPEPPFFKQLIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNRKQAVILSFEGTSPAFEVVT 4wgk B 2.58 BS03 PO4 B 1 G122 M162 H194 H196 H303 Y579 Y591 G24 M64 H96 H98 H205 Y481 Y493 3.5.1.23 Q9NR71 FSGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSIDIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQTFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGPFVAAFASSNLGDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIAKGPGQDMFDSTQIIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDVTVWLNSTHASKTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHKPKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQAEFASHGMQNMTVVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRNLAKAIATDTVANLSRGPEPPFFKQLIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNRKQAVILSFEGTSPAFEVVT 4wjt B 1.21 BS01 3P9 B 1 Y109 K117 V118 Y38 K46 V47 O32108 KPLEEAFDWDEYPVQRVTATGYTAGAESTGKNPGDPLYGLTYSGVKVKRDLYSTVAADPSVFPIGTILFIPNYGLGVVADTGSAIKGNRLDLYFETVKDVYNEWGKKTLDVYVIKKGTGKITEDELEKLNETKSLQVFRNQYKTVK 4wk9 A 1.10 BS01 CBS A 1 Y27 W31 F58 W99 N100 D138 E140 A183 M210 Y212 D213 Y267 R269 E297 M300 W358 Y6 W10 F37 W78 N79 D117 E119 A162 M189 Y191 D192 Y246 R248 E276 M279 W337 3.2.1.14 Q13231 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLVPR 4wkf A 1.10 BS01 CBS A 1 Y27 W31 F58 G98 W99 N100 F101 D138 E140 Y141 A183 M210 Y212 D213 Y267 R269 E297 M300 W358 L362 Y6 W10 F37 G77 W78 N79 F80 D117 E119 Y120 A162 M189 Y191 D192 Y246 R248 E276 M279 W337 L341 3.2.1.14 Q13231 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLVP 4wkh A 1.05 BS01 CBS A 1 W31 F58 W99 N100 D138 E140 M210 Y212 D213 Y267 R269 E297 M300 W358 W10 F37 W78 N79 D117 E119 M189 Y191 D192 Y246 R248 E276 M279 W337 3.2.1.14 Q13231 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLVPR 4wlk A 2.03 BS01 3QL A 1 Y93 S99 T100 K102 L111 T112 Y113 V118 A127 D151 T152 G153 S154 A155 D162 Y22 S28 T29 K31 L40 T41 Y42 V47 A56 D80 T81 G82 S83 A84 D91 O32108 KPLEEAFDWDEYPVQRVTATGYTAGAESTGKNPGDPLYGLTYSGVKVKRDLYSTVAADPSVFPIGTILFIPNYGLGVVADTGSAIKGNRLDLYFETVKDVYNEWGKKTLDVYVIKKGTGKITEDELEKLNETKSLQVFRNQYKTV 4wlk B 2.03 BS01 3QL B 1 Y93 S99 T100 K102 L111 V118 A127 D151 T152 G153 S154 A155 D162 Y21 S27 T28 K30 L39 V46 A55 D79 T80 G81 S82 A83 D90 O32108 PLEEAFDWDEYPVQRVTATGYTAGAESTGKNPGDPLYGLTYSGVKVKRDLYSTVAADPSVFPIGTILFIPNYGLGVVADTGSAIKGNRLDLYFETVKDVYNEWGKKTLDVYVIKKGTGKITEDELEKLNETKSLQVFRNQYKTV 4wyc A 1.70 BS01 PLP A 1 W65 S123 G124 S125 Y157 H158 G159 E220 D254 I256 A257 K283 W58 S116 G117 S118 Y150 H151 G152 E213 D247 I249 A250 K276 2.6.1.62 P9WQ81 26068403 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4wyc A 1.70 BS02 3VS A 1 P24 Y25 W64 Y157 P17 Y18 W57 Y150 2.6.1.62 P9WQ81 26068403 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4wye A 1.75 BS02 3VW A 1 Y25 W64 W65 G225 A226 M229 K283 F402 Y407 Y18 W57 W58 G218 A219 M222 K276 F395 Y400 2.6.1.62 P9WQ81 26068403 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGSL 4wyf B 2.25 BS01 3VX A 1 P24 W64 P17 W57 2.6.1.62 P9WQ81 26068403 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLV 4wyg A 1.62 BS02 3W1 A 1 Y25 W64 W65 Y157 M174 A226 R400 F402 Y18 W57 W58 Y150 M167 A219 R393 F395 2.6.1.62 P9WQ81 26068403 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGSL 4wyg B 1.62 BS04 3W1 B 1 Y25 W64 W65 Y157 A226 F402 Y18 W57 W58 Y150 A219 F395 2.6.1.62 P9WQ81 26068403 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGSL 4wyg B 1.62 BS05 3W1 B 2 R193 V222 F231 H232 D233 P234 H271 C371 R186 V215 F224 H225 D226 P227 H264 C364 2.6.1.62 P9WQ81 26068403 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGSL 4xew A 2.47 BS02 40N A 1 P24 Y25 W64 Y157 A226 R400 F402 P17 Y18 W57 Y150 A219 R393 F395 2.6.1.62 P9WQ81 26068403 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4xew B 2.47 BS04 40N B 1 P24 Y25 W64 Y157 A226 F402 P17 Y18 W57 Y150 A219 F395 2.6.1.62 P9WQ81 26068403 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4xii A 2.70 BS01 40V A 1 N68 I69 D70 W82 G116 G117 E197 S198 W231 P285 S287 F329 Y332 F398 H438 N66 I67 D68 W80 G114 G115 E195 S196 W229 P283 S285 F327 Y330 F396 H436 3.1.1.8 P06276 26116179 DIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 4xii A 2.70 BS03 FUL A 2 E482 S487 T488 T508 E480 S485 T486 T506 3.1.1.8 P06276 26116179 DIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 4xii B 2.70 BS01 40V B 1 I69 D70 W82 G116 G117 T120 E197 S198 W231 P285 L286 S287 F329 Y332 H438 G439 I66 D67 W79 G113 G114 T117 E194 S195 W228 P282 L283 S284 F326 Y329 H435 G436 3.1.1.8 P06276 26116179 IIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 4xmk L 3.18 BS01 III P 1 Y27D Y32 P91 L92 S94 Y31 Y37 P96 L97 S99 26109728 DIVMNQSPPSLAVTPGEPASISCRASQSLLYSDGHNYLDWYLQKPGQAPQLLIYLGSTRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQPLQSYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 4xmk H 3.18 BS01 III P 1 Y33 W47 Y52 D54 S56 F58 Y99 G100 D100B Y33 W47 Y52 D54 S56 F58 Y102 G103 D105 26109728 EVQLVGSGGGLIQPGGSLRLSCAASDFSVSEYYMTWVRQAPGKGLEWVAVLYKDGSQFYAPSVKGRFIVSRDNSKNSLYLQMNNLRGEDTAVYFCARENADYGSDYYFGMDVWGQGTAVAVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSSVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKAEP 4xmk M 3.18 BS01 III Q 1 Y27D D28 Y32 P91 L92 Q93 S94 Y31 D33 Y37 P96 L97 Q98 S99 26109728 DIVMNQSPPSLAVTPGEPASISCRASQSLLYSDGHNYLDWYLQKPGQAPQLLIYLGSTRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQPLQSYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 4xyb A 1.38 BS01 NDP A 1 F99 I123 N147 V151 A199 G201 R202 I203 A222 R223 H224 H255 A256 P257 Y259 T262 T283 A284 R285 D309 H333 S335 G336 S381 F98 I122 N146 V150 A198 G200 R201 I202 A221 R222 H223 H254 A255 P256 Y258 T261 T282 A283 R284 D308 H332 S334 G335 S380 1.2.1.2 G8NVB5 26104866 AKVLCVLYDDPTSGYPPLYARNAIPKIERYPDGQTVPNPKHIDFVPGELLGCVSGELGLRSYLEDLGHTFIVTSDKEGPNSVFEKELPDADIVISQPFWPAYLTAERIAKAKKLKLALTAGIGSDHVDLNAAIKAGITVAEETFSNGICVAEHAVMMILALVRNYLPSHKIAEEGGWNIADCVSRSYDLEGMHVGTVAAGRIGLAVLRRLKPFDVKLHYTARHRSPRAIEDELGLTYHATAEEMAEVCDVISIHAPLYPATEHLFNAKVLNKMRHGSYLVNTARAEICDRDDIVRALESGQLAGYAGDVWFPQPAPANHPWRNMPHNGMTPHMSGSSLSGQARYAAGTREILECWFENRPIRDEYLIVSNGKLAGTGAKSYGVG 4xyb A 1.38 BS02 AZI A 1 P98 F99 G122 I123 N147 R285 H333 P97 F98 G121 I122 N146 R284 H332 1.2.1.2 G8NVB5 26104866 AKVLCVLYDDPTSGYPPLYARNAIPKIERYPDGQTVPNPKHIDFVPGELLGCVSGELGLRSYLEDLGHTFIVTSDKEGPNSVFEKELPDADIVISQPFWPAYLTAERIAKAKKLKLALTAGIGSDHVDLNAAIKAGITVAEETFSNGICVAEHAVMMILALVRNYLPSHKIAEEGGWNIADCVSRSYDLEGMHVGTVAAGRIGLAVLRRLKPFDVKLHYTARHRSPRAIEDELGLTYHATAEEMAEVCDVISIHAPLYPATEHLFNAKVLNKMRHGSYLVNTARAEICDRDDIVRALESGQLAGYAGDVWFPQPAPANHPWRNMPHNGMTPHMSGSSLSGQARYAAGTREILECWFENRPIRDEYLIVSNGKLAGTGAKSYGVG 4xye A 1.80 BS01 NAD A 1 F99 I123 N147 V151 V198 A199 G201 R202 I203 A222 R223 H255 A256 P257 Y259 T262 A284 R285 H333 S335 G336 S381 F98 I122 N146 V150 V197 A198 G200 R201 I202 A221 R222 H254 A255 P256 Y258 T261 A283 R284 H332 S334 G335 S380 1.2.1.2 G8NVB5 26104866 AKVLCVLYDDPTSGYPPLYARNAIPKIERYPDGQTVPNPKHIDFVPGELLGCVSGELGLRSYLEDLGHTFIVTSDKEGPNSVFEKELPDADIVISQPFWPAYLTAERIAKAKKLKLALTAGIGSDHVDLNAAIKAGITVAEETFSNGICVAEHAVMMILALVRNYLPSHKIAEEGGWNIADCVSRSYDLEGMHVGTVAAGRIGLAVLRRLKPFDVKLHYTARHRSPRAIEDELGLTYHATAEEMAEVCDVISIHAPLYPATEHLFNAKVLNKMRHGSYLVNTARAEICDRDDIVRALESGQLAGYAGDVWFPQPAPANHPWRNMPHNGMTPHMSGSSLSGQARYAAGTREILECWFENRPIRDEYLIVSNGKLAGTGAKSYGVG 4xye B 1.80 BS01 NAD B 1 I123 N147 V151 A199 G201 R202 I203 R223 H255 P257 Y259 T262 T283 A284 R285 D309 V310 H333 S335 G336 S381 I122 N146 V150 A198 G200 R201 I202 R222 H254 P256 Y258 T261 T282 A283 R284 D308 V309 H332 S334 G335 S380 1.2.1.2 G8NVB5 26104866 AKVLCVLYDDPTSGYPPLYARNAIPKIERYPDGQTVPNPKHIDFVPGELLGCVSGELGLRSYLEDLGHTFIVTSDKEGPNSVFEKELPDADIVISQPFWPAYLTAERIAKAKKLKLALTAGIGSDHVDLNAAIKAGITVAEETFSNGICVAEHAVMMILALVRNYLPSHKIAEEGGWNIADCVSRSYDLEGMHVGTVAAGRIGLAVLRRLKPFDVKLHYTARHRSPRAIEDELGLTYHATAEEMAEVCDVISIHAPLYPATEHLFNAKVLNKMRHGSYLVNTARAEICDRDDIVRALESGQLAGYAGDVWFPQPAPANHPWRNMPHNGMTPHMSGSSLSGQARYAAGTREILECWFENRPIRDEYLIVSNGKLAGTGAKSYGVG 4yhj A 2.60 BS01 AN2 A 1 G194 G197 V201 A214 T265 M267 L319 D330 G170 G173 V177 A190 T241 M243 L295 D306 2.7.11.16 P32298 GRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDI 4yhj B 2.60 BS01 AN2 B 1 G194 K195 G196 G197 V201 A214 K216 T265 M267 L319 D330 G170 K171 G172 G173 V177 A190 K192 T241 M243 L295 D306 2.7.11.16 P32298 GRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINK 4ylf A 2.30 BS01 FES A 1 M218 V219 D220 G221 G223 M224 C225 G226 A227 C228 C240 M218 V219 D220 G221 G223 M224 C225 G226 A227 C228 C240 Q9X1X4 MGGTALNEIVKKVKIAEDVFDFWIHSPSVSKEARPGQFVVIRLHEKGERIPLTVADTKPEEGLFRMVVKVVGKTTHELSLKKEGDTILDVVGPLGNPSEIENYGNVLLVGGGVGIATLYPIAKALKEAGNNITTVLGARTKDYLIMVDEFKEISDVLLVTDDGSAGMKGVVTDAMDKLFRERKFDICWAVGPTIMMKFCTLKAREFGVPIWVSLNPIMVDGTGMCGACRVTVSGQIKFACVDGPEFRGEEVDWDELLKRLAQYREQEKISYERFLK 4ylf A 2.30 BS02 FAD A 1 E48 P51 L52 T53 V67 V68 K69 G72 K73 T74 T75 T117 N215 P216 I217 M218 L260 Q266 I269 E48 P51 L52 T53 V67 V68 K69 G72 K73 T74 T75 T117 N215 P216 I217 M218 L260 Q266 I269 Q9X1X4 MGGTALNEIVKKVKIAEDVFDFWIHSPSVSKEARPGQFVVIRLHEKGERIPLTVADTKPEEGLFRMVVKVVGKTTHELSLKKEGDTILDVVGPLGNPSEIENYGNVLLVGGGVGIATLYPIAKALKEAGNNITTVLGARTKDYLIMVDEFKEISDVLLVTDDGSAGMKGVVTDAMDKLFRERKFDICWAVGPTIMMKFCTLKAREFGVPIWVSLNPIMVDGTGMCGACRVTVSGQIKFACVDGPEFRGEEVDWDELLKRLAQYREQEKISYERFLK 4ylf B 2.30 BS01 SF4 B 1 C39 L40 C42 C47 C100 V101 V111 I113 C39 L40 C42 C47 C100 V101 V111 I113 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4ylf B 2.30 BS02 SF4 B 2 C51 P52 I55 N80 C90 Q92 Q95 C96 E117 I442 C51 P52 I55 N80 C90 Q92 Q95 C96 E117 I442 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4ylf B 2.30 BS03 FAD B 1 V89 G147 S148 G149 P150 A151 F169 E170 A171 F172 G177 V178 Y181 I183 R187 T211 V213 G232 T233 G234 L258 N289 T290 D293 L399 G432 D433 T440 V441 A444 V89 G147 S148 G149 P150 A151 F169 E170 A171 F172 G177 V178 Y181 I183 R187 T211 V213 G232 T233 G234 L258 N289 T290 D293 L399 G432 D433 T440 V441 A444 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4ylf C 2.30 BS01 FAD C 1 F38 E48 P51 L52 T53 V67 V68 K69 V71 G72 T74 T75 N215 P216 M218 L260 A261 Q266 F38 E48 P51 L52 T53 V67 V68 K69 V71 G72 T74 T75 N202 P203 M205 L247 A248 Q253 Q9X1X4 MGGTALNEIVKKVKIAEDVFDFWIHSPSVSKEARPGQFVVIRLHEKGERIPLTVADTKPEEGLFRMVVKVVGKTTHELSLKKEGDTILDVVGPLGNPSEIENYGNVLLVGGGVGIATLYPIAKALKEAGNNITTVLGARTKDYLIMVDEFKEISDVLLVTDDGSAGMKGKFDICWAVGPTIMMKFCTLKAREFGVPIWVSLNPIMVDGTGMCGACRVTVSGQIKFACVDGPEFRGEEVDWDELLKRLAQYREQEKISYERFLK 4ylf D 2.30 BS01 SF4 D 1 C39 L40 C42 C47 I57 P58 C100 V101 V102 V111 C39 L40 C42 C47 I57 P58 C100 V101 V102 V111 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4ylf D 2.30 BS02 SF4 D 2 C51 P52 I55 C86 C90 Q92 Q95 C96 E117 I442 C51 P52 I55 C86 C90 Q92 Q95 C96 E117 I442 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4ylf D 2.30 BS03 FAD D 1 V89 P91 G147 G149 P150 A151 E170 A171 G177 V178 Y181 G182 I183 R187 V212 V213 G232 T233 G234 L258 N289 T290 D293 L399 G432 D433 A439 T440 V441 A444 V89 P91 G147 G149 P150 A151 E170 A171 G177 V178 Y181 G182 I183 R187 V212 V213 G232 T233 G234 L258 N289 T290 D293 L399 G432 D433 A439 T440 V441 A444 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4yoa A 1.70 BS01 017 A 1 N25 G27 A28 D29 T82 V84 N25 G27 A28 D29 T82 V84 Q5RTL1 PQITLWKRPIVTIKIGGQLKEALLNTGADDTVFEEVNLPGRWKPKLIGGIGGFVKVRQYDQVPIEICGHKVIGTVLVGPTPTNVIGRNLMTQIGCTLNF 4yry A 2.40 BS02 FAD A 1 F38 E48 P51 L52 T53 V67 V68 K69 V71 G72 K73 T74 T75 N215 P216 M218 L260 Q266 I269 F38 E48 P51 L52 T53 V67 V68 K69 V71 G72 K73 T74 T75 N215 P216 M218 L260 Q266 I269 Q9X1X4 MGGTALNEIVKKVKIAEDVFDFWIHSPSVSKEARPGQFVVIRLHEKGERIPLTVADTKPEEGLFRMVVKVVGKTTHELSLKKEGDTILDVVGPLGNPSEIENYGNVLLVGGGVGIATLYPIAKALKEAGNNITTVLGARTKDYLIMVDEFKEISDVLLVTDDGSAGMKGVVTDAMDKLFRERKFDICWAVGPTIMMKFCTLKAREFGVPIWVSLNPIMVDGTGMCGACRVTVSGQIKFACVDGPEFRGEEVDWDELLKRLAQYREQEKISYERFLK 4yry A 2.40 BS03 NAD A 1 K69 G111 G112 V113 G114 T117 G137 A138 R139 V170 V171 V190 G191 P192 I194 M195 M196 F198 S213 N215 K69 G111 G112 V113 G114 T117 G137 A138 R139 V170 V171 V190 G191 P192 I194 M195 M196 F198 S213 N215 Q9X1X4 MGGTALNEIVKKVKIAEDVFDFWIHSPSVSKEARPGQFVVIRLHEKGERIPLTVADTKPEEGLFRMVVKVVGKTTHELSLKKEGDTILDVVGPLGNPSEIENYGNVLLVGGGVGIATLYPIAKALKEAGNNITTVLGARTKDYLIMVDEFKEISDVLLVTDDGSAGMKGVVTDAMDKLFRERKFDICWAVGPTIMMKFCTLKAREFGVPIWVSLNPIMVDGTGMCGACRVTVSGQIKFACVDGPEFRGEEVDWDELLKRLAQYREQEKISYERFLK 4yry B 2.40 BS01 SF4 B 1 C39 L40 Q41 C42 C47 C100 V101 V102 I113 C39 L40 Q41 C42 C47 C100 V101 V102 I113 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4yry B 2.40 BS03 FAD B 1 V89 P91 G147 G149 P150 A151 E170 A171 F172 G177 V178 Y181 I183 R187 T211 V213 T233 G234 N289 T290 Q393 L399 G432 D433 A439 T440 V441 A444 V89 P91 G147 G149 P150 A151 E170 A171 F172 G177 V178 Y181 I183 R187 T211 V213 T233 G234 N289 T290 Q393 L399 G432 D433 A439 T440 V441 A444 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4yry C 2.40 BS02 FAD C 1 E48 I50 P51 L52 T53 V67 V68 K69 V71 G72 T74 T75 I115 N215 P216 I217 M218 L260 Q266 E267 S270 E48 I50 P51 L52 T53 V67 V68 K69 V71 G72 T74 T75 I115 N204 P205 I206 M207 L249 Q255 E256 S259 Q9X1X4 MGGTALNEIVKKVKIAEDVFDFWIHSPSVSKEARPGQFVVIRLHEKGERIPLTVADTKPEEGLFRMVVKVVGKTTHELSLKKEGDTILDVVGPLGNPSEIENYGNVLLVGGGVGIATLYPIAKALKEAGNNITTVLGARTKDYLIMVDEFKEISDVLLVTDDGSAGMKGVVTDRERKFDICWAVGPTIMMKFCTFGVPIWVSLNPIMVDGTGMCGACRVTVSGQIKFACVDGPEFRGEEVDWDELLKRLAQYREQEKISYERFLK 4yry D 2.40 BS01 SF4 D 1 C39 L40 Q41 C42 C47 C100 V101 V102 V111 C39 L40 Q41 C42 C47 C100 V101 V102 V111 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4yry D 2.40 BS02 SF4 D 2 C51 I55 C86 C90 Q92 Q95 C96 I113 E117 I442 C51 I55 C86 C90 Q92 Q95 C96 I113 E117 I442 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4yry D 2.40 BS03 FAD D 1 V89 G147 S148 G149 P150 A151 F169 E170 A171 G177 V178 G182 I183 R187 T211 V212 V213 G232 T233 G234 L258 N289 T290 D293 G432 D433 A439 T440 V441 V89 G147 S148 G149 P150 A151 F169 E170 A171 G177 V178 G182 I183 R187 T211 V212 V213 G232 T233 G234 L258 N289 T290 D293 G432 D433 A439 T440 V441 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4yry D 2.40 BS04 NAD D 1 K239 G288 N289 T290 Y310 R311 R371 P372 I391 G392 A438 A439 K239 G288 N289 T290 Y310 R311 R371 P372 I391 G392 A438 A439 MKNRKTPMKEQSPESRRRNFEEVALGYTLEEALEEAQRCLQCPTHPCVSGCPVEIDIPGFIRKLRDGKLEESYRILKSYNNLPAVCGRVCPQEVQCESRCVVGKMKDSEPVAIGRLERFVADWAAENLEEDVKPLAGSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVYGIPEFRLPKRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQFIHSYLTGEWNPWQK 4zkb A 2.90 BS01 III B 1 L139 E140 E142 L143 D204 F205 S206 L207 L208 V209 D210 P211 R212 Y242 L129 E130 E132 L133 D153 F154 S155 L156 L157 V158 D159 P160 R161 Y191 Q2F862 26095031 SEEKANFCSTHNDEVYARFRLQMRVGVRHSPLYTPSNMCMLDIEDSVEDIEESTEKEYASTATGEAAGVNVSVALVGEGVSIPFSYIGLGFNPSLEDSYLYVNVSSRAPWVKQTSDLSANGGWGIKQVLEKELLAIQIGCDNQKFPENPADIDFSLLVDPRCVTSVDLHVELRDACIDYKQESPLSLKGKYGDGELVKKEIKDVGKNHNMCSLNLNPG 4zkb A 2.90 BS02 III B 2 E67 V86 Q147 S206 E57 V76 Q137 S155 Q2F862 26095031 SEEKANFCSTHNDEVYARFRLQMRVGVRHSPLYTPSNMCMLDIEDSVEDIEESTEKEYASTATGEAAGVNVSVALVGEGVSIPFSYIGLGFNPSLEDSYLYVNVSSRAPWVKQTSDLSANGGWGIKQVLEKELLAIQIGCDNQKFPENPADIDFSLLVDPRCVTSVDLHVELRDACIDYKQESPLSLKGKYGDGELVKKEIKDVGKNHNMCSLNLNPG 4znl A 2.07 BS01 BEF A 1 Q40 K43 Q39 K42 A7XXR1 KRLRPSDKFFELLGYKPHHVQLAIHRSTAKRRVACLGRQSGKSEAASVEAVFELFARPGSQGWIIAPTYDQAEIIFGRVVEKVERLAEVFPATEVQLQRRRLRLLVHHYDRPVNAPGAKRVATSEFRGKSADRPDNLRGATLDFVILDEAAMIPFSVWSEAIEPTLSVRDGWALIISTPKGLNWFYEFFLMGWRGGLKEGIPNSGINQTHPDFESFHAASWDVWPERREWYMERRLYIPDLEFRQEYGAEFVS 4znl A 2.07 BS02 ADP A 1 K17 P18 H19 Q22 Q40 S41 G42 K43 S44 E45 R79 W225 K16 P17 H18 Q21 Q39 S40 G41 K42 S43 E44 R78 W224 A7XXR1 KRLRPSDKFFELLGYKPHHVQLAIHRSTAKRRVACLGRQSGKSEAASVEAVFELFARPGSQGWIIAPTYDQAEIIFGRVVEKVERLAEVFPATEVQLQRRRLRLLVHHYDRPVNAPGAKRVATSEFRGKSADRPDNLRGATLDFVILDEAAMIPFSVWSEAIEPTLSVRDGWALIISTPKGLNWFYEFFLMGWRGGLKEGIPNSGINQTHPDFESFHAASWDVWPERREWYMERRLYIPDLEFRQEYGAEFVS 4znl B 2.07 BS01 BEF B 1 R39 Q40 K43 R38 Q39 K42 A7XXR1 KRLRPSDKFFELLGYKPHHVQLAIHRSTAKRRVACLGRQSGKSEAASVEAVFELFARPGSQGWIIAPTYDQAEIIFGRVVEKVERLAEVFPATEVQLQRRRLRLLVHHYDRPVNAPGAKRVATSEFRGKSADRPDNLRGATLDFVILDEAAMIPFSVWSEAIEPTLSVRDGWALIISTPKGLNWFYEFFLMGWRGGLKEGIPNSGINQTHPDFESFHAASWDVWPERREWYMERRLYIPDLEFRQEYGAEFVSH 4znl B 2.07 BS02 ADP B 1 K17 H19 Q22 Q40 S41 G42 K43 S44 E45 R79 W225 K16 H18 Q21 Q39 S40 G41 K42 S43 E44 R78 W224 A7XXR1 KRLRPSDKFFELLGYKPHHVQLAIHRSTAKRRVACLGRQSGKSEAASVEAVFELFARPGSQGWIIAPTYDQAEIIFGRVVEKVERLAEVFPATEVQLQRRRLRLLVHHYDRPVNAPGAKRVATSEFRGKSADRPDNLRGATLDFVILDEAAMIPFSVWSEAIEPTLSVRDGWALIISTPKGLNWFYEFFLMGWRGGLKEGIPNSGINQTHPDFESFHAASWDVWPERREWYMERRLYIPDLEFRQEYGAEFVSH 4zsw A 1.70 BS02 RW2 A 1 C135 G136 S137 N140 F189 H190 G191 R192 E265 E270 D298 V300 Q301 K329 R445 C125 G126 S127 N130 F179 H180 G181 R182 E255 E260 D288 V290 Q291 K319 R435 2.6.1.19,2.6.1.22 P80147 26110556 FDYDGPLMKTEVPGPRSRELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSIPIGYSHPALVKLVQQPQNVSTFINRPALGILPPENFVEKLRESLLSVAPKGMSQLITMACGSCSNENAFKTIFMWYRSKERGESAFSKEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDISRKHGCAFLVDEVQTGGGSTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLSNAAHAGKVLLTGLLDLQARYPQFISRVRGRGTFCSFDTPDESIRNKLISIARNKGVMLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADF 4zt0 A 2.90 BS01 NUC B 1 K33 L35 G56 E57 T58 A59 T62 R63 K65 R66 R69 R70 R71 Y72 R74 R75 K76 N77 R78 Y81 L101 S104 F105 K111 R115 H116 P117 I122 V126 H129 P133 T134 I135 H160 K163 F164 R165 G166 H167 F168 Y325 H328 H329 K336 F351 F352 Y359 A360 I363 G366 K401 Q402 R403 T404 F405 N407 G408 F446 R447 I448 Y450 G453 P454 L455 A456 R457 N459 S460 F462 W464 R467 T472 I473 P475 M495 N497 L727 A728 S730 K734 K735 L738 Q739 K742 R753 K1097 E1099 V1100 T1102 G1103 G1104 F1105 I1110 P1112 K1113 R1122 K1123 K1124 W1126 K1130 Y1131 M1169 H1349 Q1350 S1351 Y1356 E1357 T1358 K31 L33 G54 E55 T56 A57 T60 R61 K63 R64 R67 R68 R69 Y70 R72 R73 K74 N75 R76 Y79 L99 S102 F103 K109 R113 H114 P115 I120 V124 H127 P131 T132 I133 H158 K161 F162 R163 G164 H165 F166 Y323 H326 H327 K334 F349 F350 Y357 A358 I361 G364 K399 Q400 R401 T402 F403 N405 G406 F444 R445 I446 Y448 G451 P452 L453 A454 R455 N457 S458 F460 W462 R465 T470 I471 P473 M493 N495 L725 A726 S728 K732 K733 L736 Q737 K740 R751 K1095 E1097 V1098 T1100 G1101 G1102 F1103 I1108 P1110 K1111 R1120 K1121 K1122 W1124 K1128 Y1129 M1167 H1347 Q1348 S1349 Y1354 E1355 T1356 3.1.-.- A0A0C6FZC2 26113724 KKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 4zt0 C 2.90 BS01 NUC D 1 K33 L35 G56 E57 T58 A59 T62 R63 K65 R66 R69 R70 R71 Y72 R74 R75 K76 N77 R78 Y81 L101 S104 F105 L106 K111 R115 H116 P117 I122 V126 H129 P133 T134 I135 H160 K163 F164 R165 G166 H167 Y325 H328 H329 K336 R340 F351 F352 Y359 A360 I363 D364 G366 K401 Q402 R403 T404 F405 N407 G408 F446 R447 I448 Y450 G453 P454 L455 A456 R457 N459 S460 F462 W464 R467 T472 I473 P475 L727 A728 S730 K734 K735 L738 Q739 K742 K749 E1099 V1100 T1102 G1103 G1104 F1105 I1110 P1112 K1113 R1122 K1123 K1124 W1126 K1130 Y1131 M1169 S1172 H1349 Q1350 S1351 Y1356 E1357 T1358 K30 L32 G53 E54 T55 A56 T59 R60 K62 R63 R66 R67 R68 Y69 R71 R72 K73 N74 R75 Y78 L98 S101 F102 L103 K108 R112 H113 P114 I119 V123 H126 P130 T131 I132 H157 K160 F161 R162 G163 H164 Y322 H325 H326 K333 R337 F348 F349 Y356 A357 I360 D361 G363 K398 Q399 R400 T401 F402 N404 G405 F443 R444 I445 Y447 G450 P451 L452 A453 R454 N456 S457 F459 W461 R464 T469 I470 P472 L724 A725 S727 K731 K732 L735 Q736 K739 K746 E1029 V1030 T1032 G1033 G1034 F1035 I1040 P1042 K1043 R1052 K1053 K1054 W1056 K1060 Y1061 M1099 S1102 H1279 Q1280 S1281 Y1286 E1287 T1288 3.1.-.- A0A0C6FZC2 26113724 KYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMAREKNSRERMKRIEEGIKELGSQILKEHPVEKLYLYYLQNGRDMYVDQELDINSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKPSEEVVKKMKNYWRITQRKFDNGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRSNIMNFFKTEIIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 4zt9 A 3.10 BS01 NUC B 1 K33 L35 G56 E57 T58 A59 T62 R63 K65 R66 R69 R70 R71 Y72 R74 R75 K76 N77 R78 Y81 L101 S104 F105 L106 V107 K111 R115 H116 P117 I122 V126 H129 T134 I135 H160 K163 F164 R165 G166 H167 F168 Y325 H328 H329 L332 R340 F351 F352 Y359 D364 G366 K401 Q402 R403 T404 F405 N407 G408 F446 R447 I448 Y450 G453 P454 L455 A456 R457 N459 S460 F462 W464 T472 I473 P475 N497 S730 P731 K735 L738 Q739 K742 K1097 E1099 V1100 T1102 G1103 G1104 F1105 I1110 P1112 K1113 R1122 K1123 K1124 W1126 K1130 Y1131 M1169 H1349 Q1350 S1351 Y1356 E1357 K31 L33 G54 E55 T56 A57 T60 R61 K63 R64 R67 R68 R69 Y70 R72 R73 K74 N75 R76 Y79 L99 S102 F103 L104 V105 K109 R113 H114 P115 I120 V124 H127 T132 I133 H158 K161 F162 R163 G164 H165 F166 Y317 H320 H321 L324 R332 F343 F344 Y351 D356 G358 K393 Q394 R395 T396 F397 N399 G400 F438 R439 I440 Y442 G445 P446 L447 A448 R449 N451 S452 F454 W456 T464 I465 P467 N489 S715 P716 K720 L723 Q724 K727 K1064 E1066 V1067 T1069 G1070 G1071 F1072 I1077 P1079 K1080 R1089 K1090 K1091 W1093 K1097 Y1098 M1136 H1316 Q1317 S1318 Y1323 E1324 3.1.-.- A0A0C6FZC2 26113724 KKYSIGLAIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMASRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDAIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLGGD 4zt9 C 3.10 BS01 NUC D 1 K33 L35 G56 E57 T58 A59 T62 R63 K65 R66 R69 R70 R71 Y72 R74 R75 K76 N77 R78 Y81 L101 S104 F105 L106 K111 R115 H116 P117 I122 E125 V126 H129 T134 I135 H160 K163 F164 R165 G166 F168 Y325 H328 H329 K336 R340 F351 F352 Y359 A360 I363 D364 G366 K401 Q402 R403 T404 F405 N407 G408 F446 R447 I448 Y450 G453 P454 L455 A456 R457 N459 S460 F462 W464 R467 T472 I473 P475 F491 N497 A728 S730 P731 K734 K735 L738 Q739 K742 K749 R753 K1097 E1099 V1100 T1102 G1103 G1104 F1105 I1110 P1112 K1113 R1122 K1123 K1124 W1126 K1130 Y1131 M1169 S1172 H1349 Q1350 S1351 Y1356 E1357 K30 L32 G53 E54 T55 A56 T59 R60 K62 R63 R66 R67 R68 Y69 R71 R72 K73 N74 R75 Y78 L98 S101 F102 L103 K108 R112 H113 P114 I119 E122 V123 H126 T131 I132 H157 K160 F161 R162 G163 F165 Y316 H319 H320 K327 R331 F342 F343 Y350 A351 I354 D355 G357 K392 Q393 R394 T395 F396 N398 G399 F437 R438 I439 Y441 G444 P445 L446 A447 R448 N450 S451 F453 W455 R458 T463 I464 P466 F482 N488 A695 S697 P698 K701 K702 L705 Q706 K709 K716 R720 K899 E901 V902 T904 G905 G906 F907 I912 P914 K915 R924 K925 K926 W928 K932 Y933 M971 S974 H1143 Q1144 S1145 Y1150 E1151 3.1.-.- A0A0C6FZC2 26113724 KYSIGLAIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARDAIVPQSFLKDDSIDNGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYYSNIMNFFKTEIIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 5a3n A 2.00 BS05 LQT A 1 R98 Y425 W486 Y488 F496 H499 E501 K517 W519 H587 V600 N601 R75 Y128 W189 Y191 F199 H202 E204 K220 W222 H290 V303 N304 1.14.11.- Q9UGL1 SMFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKRDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAE 5a5z A 2.60 BS03 WJZ A 1 V73 W93 D124 H189 C208 N220 H250 V37 W57 D88 H153 C172 N184 H214 3.5.2.6 C7C422 25815530 QQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLRLE 5a5z C 2.60 BS03 WJZ C 1 M67 H189 C208 K211 L218 G219 N220 H250 M31 H153 C172 K175 L182 G183 N184 H214 3.5.2.6 C7C422 25815530 QQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLRLE 5ait A 3.40 BS01 ZN A 1 C136 C139 C163 C166 C6 C9 C33 C36 6.3.2.- O88846 SGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYIGSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI 5ait A 3.40 BS02 ZN A 2 C158 H160 C177 C180 C28 H30 C47 C50 6.3.2.- O88846 SGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYIGSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIYI 5brm A 2.65 BS01 III G 1 P91 R92 Y93 E94 Y95 H96 W97 A98 P106 K153 R154 R157 Y163 H164 F167 D168 M171 E176 N180 R199 E200 L204 E206 L207 P40 R41 Y42 E43 Y44 H45 W46 A47 P55 K96 R97 R100 Y106 H107 F110 D111 M114 E119 N123 R142 E143 L147 E149 L150 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm A 2.65 BS02 III M 1 A58 V62 F65 N66 N69 Y72 T76 I115 D116 M119 Q123 L126 D127 F132 A7 V11 F14 N15 N18 Y21 T25 I64 D65 M68 Q72 L75 D76 F81 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm B 2.65 BS01 III H 1 P91 R92 Y93 E94 Y95 H96 W97 A98 I103 K153 R154 R157 R199 E200 A202 P40 R41 Y42 E43 Y44 H45 W46 A47 I52 K99 R100 R103 R145 E146 A148 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG 5brm B 2.65 BS02 III H 2 Y163 F167 M171 E176 N180 L207 K210 Y109 F113 M117 E122 N126 L153 K156 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG 5brm B 2.65 BS03 III N 1 A58 V59 N66 N69 Y72 I115 D116 M119 Q123 L126 D127 S134 A7 V8 N15 N18 Y21 I64 D65 M68 Q72 L75 D76 S83 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG 5brm C 2.65 BS01 III I 1 P91 R92 E94 Y95 H96 R154 R157 R199 E200 P40 R41 E43 Y44 H45 R103 R106 R148 E149 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm C 2.65 BS02 III I 2 Y163 H164 F167 E176 N180 L207 K210 Y112 H113 F116 E125 N129 L156 K159 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm C 2.65 BS03 III N 1 V62 F65 N66 N69 Q123 L126 F132 P133 S134 K135 I136 V11 F14 N15 N18 Q72 L75 F81 P82 S83 K84 I85 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm D 2.65 BS01 III J 1 P91 R92 Y93 E94 Y95 H96 W97 R154 R157 R199 E200 A202 P40 R41 Y42 E43 Y44 H45 W46 R87 R90 R132 E133 A135 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWKCSAPKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm D 2.65 BS02 III J 2 Y163 H164 F167 M171 E176 N180 L204 E206 L207 K210 Y96 H97 F100 M104 E109 N113 L137 E139 L140 K143 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWKCSAPKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm D 2.65 BS03 III O 1 A58 V59 V62 F65 N66 N69 M70 Y72 Q123 L126 D127 A7 V8 V11 F14 N15 N18 M19 Y21 Q62 L65 D66 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWKCSAPKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm E 2.65 BS01 III K 1 R92 Y93 E94 Y95 H96 A98 D99 P106 K153 R154 R157 E200 R41 Y42 E43 Y44 H45 A47 D48 P55 K102 R103 R106 E149 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm E 2.65 BS02 III K 2 Y163 H164 F167 E176 N180 L204 E206 L207 Y112 H113 F116 E125 N129 L153 E155 L156 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm E 2.65 BS03 III O 1 V59 V62 F65 N66 Q123 L126 P133 S134 V8 V11 F14 N15 Q72 L75 P82 S83 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm F 2.65 BS01 III L 1 P91 R92 Y93 E94 Y95 H96 P106 K153 R154 R157 R199 E200 P40 R41 Y42 E43 Y44 H45 P55 K102 R103 R106 R148 E149 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm F 2.65 BS02 III L 2 Y163 F167 N180 L204 E206 L207 K210 Y112 F116 N129 L153 E155 L156 K159 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5brm F 2.65 BS03 III M 1 A58 V62 F65 N66 N69 T76 K113 D116 Q123 L126 F132 P133 S134 I136 F140 A7 V11 F14 N15 N18 T25 K62 D65 Q72 L75 F81 P82 S83 I85 F89 Q9H8S9 26108669 DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL 5bs7 B 3.30 BS01 III F 1 L61 A91 A95 A98 Y99 L2 A32 A36 A39 Y40 P84233 26109053 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 5bs7 D 3.30 BS01 III F 1 F61 V87 L90 F36 V62 L65 P62799 26109053 IQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 5bsa B 4.61 BS01 III F 1 A91 E94 A95 A98 Y99 A32 E35 A36 A39 Y40 P84233 26109053 LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 5bsa D 4.61 BS01 III F 1 M84 V87 M59 V62 P62799 26109053 IQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQ 5btr A 3.20 BS01 III D 1 L206 T209 N226 R274 F297 H363 V412 F414 G415 E416 N417 L418 V445 R446 L46 T49 N66 R114 F137 H203 V252 F254 G255 E256 N257 L258 V285 R286 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNGSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGAGVSVSSGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSSNPVKLSEITEQYLFLPPNRYIFHGAEVY 5btr A 3.20 BS02 ZN A 1 C371 C374 C395 C398 C211 C214 C235 C238 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNGSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGAGVSVSSGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSSNPVKLSEITEQYLFLPPNRYIFHGAEVY 5btr A 3.20 BS03 STL A 1 T209 P212 D292 Q294 A295 D298 F414 K444 T49 P52 D132 Q134 A135 D138 F254 K284 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNGSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGAGVSVSSGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSSNPVKLSEITEQYLFLPPNRYIFHGAEVY 5btr A 3.20 BS04 STL D 1 L202 L206 P211 I223 N226 E230 R446 P447 L450 L42 L46 P51 I63 N66 E70 R286 P287 L290 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNGSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGAGVSVSSGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSSNPVKLSEITEQYLFLPPNRYIFHGAEVY 5btr A 3.20 BS05 STL D 2 L215 T219 Q222 N226 D298 E300 F414 G415 L55 T59 Q62 N66 D138 E140 F254 G255 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNGSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGAGVSVSSGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSSNPVKLSEITEQYLFLPPNRYIFHGAEVY 5btr B 3.20 BS01 III E 1 L206 N226 F297 H363 V412 F414 G415 E416 N417 L418 V445 R446 P447 L48 N68 F139 H205 V254 F256 G257 E258 N259 L260 V287 R288 P289 3.5.1.- Q96EB6 26109052 SRDNLLFGDEIITNGSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGAGVSVSSGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSSNITEQYLFLPPNRYIFHGAEVY 5btr B 3.20 BS03 STL B 1 R274 D292 Q294 A295 D298 F414 K444 R116 D134 Q136 A137 D140 F256 K286 3.5.1.- Q96EB6 26109052 SRDNLLFGDEIITNGSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGAGVSVSSGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSSNITEQYLFLPPNRYIFHGAEVY 5btr B 3.20 BS04 STL B 2 P212 L215 Q222 I223 N226 D298 F414 G415 P54 L57 Q64 I65 N68 D140 F256 G257 3.5.1.- Q96EB6 26109052 SRDNLLFGDEIITNGSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGAGVSVSSGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSSNITEQYLFLPPNRYIFHGAEVY 5btr B 3.20 BS05 STL E 1 L206 P211 I223 N226 E230 R446 P447 L48 P53 I65 N68 E72 R288 P289 3.5.1.- Q96EB6 26109052 SRDNLLFGDEIITNGSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGAGVSVSSGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSSNITEQYLFLPPNRYIFHGAEVY 5btr C 3.20 BS01 III F 1 L206 T209 N226 F297 H363 V412 F413 F414 G415 E416 N417 K444 V445 R446 P447 L44 T47 N64 F117 H183 V223 F224 F225 G226 E227 N228 K255 V256 R257 P258 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSFLPPNRYIFH 5btr C 3.20 BS02 ZN C 1 C371 C374 C395 C191 C194 C215 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSFLPPNRYIFH 5btr C 3.20 BS03 STL C 1 T209 P212 D292 Q294 D298 K444 T47 P50 D112 Q114 D118 K255 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSFLPPNRYIFH 5btr C 3.20 BS04 STL C 2 P212 L215 T219 Q222 I223 N226 F414 G415 P50 L53 T57 Q60 I61 N64 F225 G226 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSFLPPNRYIFH 5btr C 3.20 BS05 STL F 1 L206 P211 I223 N226 E230 R446 P447 L450 L44 P49 I61 N64 E68 R257 P258 L261 3.5.1.- Q96EB6 26109052 DNLLFGDEIITNDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLSFLPPNRYIFH 5bud A 1.99 BS01 NUC D 1 R159 M163 C166 E167 G170 Y171 E174 E244 L245 K246 T247 R249 Q256 S259 K263 Q270 R284 R160 M164 C167 E168 G171 Y172 E175 E245 L246 K247 T248 R250 Q257 S260 K264 Q271 R285 3.6.1.- Q5AAT0 26101253 HMAKSLPLNSRSKTTALKQPRELFSYARDIDGKYVYDDPENSLSYYYLPDSTIDTGIDLQGGYSKFKKIPDEQNLADFNSLLKAIIKYETSEGKKISSDIITFREIMTKILSLPYNLTDPIDLYVVPFDGQLFIKSDDELDMKRRKEQEVRMKQTNTVERYDYMKRCEYVGYKFETIATIPKPWSQVSRSQIENRNKKVVNNYEQYLSVIRTGIGNVKLVLAGEIDCCWDYLPDEQNKKLNHYVELKTSRIIENNSQVVSFEQKLFKAWCQCFLMGVTKIIYGFRDNNLILKNVELFNTEEIPILIKNNPLTNAATEKKINCTNALKWYGAVVDWLNTTVDKKDEIKSYRLKYDPVRKSFTLSETDSETNEKLRNGQLLTPEFTEWRQSLK 5bud A 1.99 BS02 MN A 1 D225 E244 L245 D226 E245 L246 3.6.1.- Q5AAT0 26101253 HMAKSLPLNSRSKTTALKQPRELFSYARDIDGKYVYDDPENSLSYYYLPDSTIDTGIDLQGGYSKFKKIPDEQNLADFNSLLKAIIKYETSEGKKISSDIITFREIMTKILSLPYNLTDPIDLYVVPFDGQLFIKSDDELDMKRRKEQEVRMKQTNTVERYDYMKRCEYVGYKFETIATIPKPWSQVSRSQIENRNKKVVNNYEQYLSVIRTGIGNVKLVLAGEIDCCWDYLPDEQNKKLNHYVELKTSRIIENNSQVVSFEQKLFKAWCQCFLMGVTKIIYGFRDNNLILKNVELFNTEEIPILIKNNPLTNAATEKKINCTNALKWYGAVVDWLNTTVDKKDEIKSYRLKYDPVRKSFTLSETDSETNEKLRNGQLLTPEFTEWRQSLK 5bud A 1.99 BS03 MN A 2 E223 D225 E224 D226 3.6.1.- Q5AAT0 26101253 HMAKSLPLNSRSKTTALKQPRELFSYARDIDGKYVYDDPENSLSYYYLPDSTIDTGIDLQGGYSKFKKIPDEQNLADFNSLLKAIIKYETSEGKKISSDIITFREIMTKILSLPYNLTDPIDLYVVPFDGQLFIKSDDELDMKRRKEQEVRMKQTNTVERYDYMKRCEYVGYKFETIATIPKPWSQVSRSQIENRNKKVVNNYEQYLSVIRTGIGNVKLVLAGEIDCCWDYLPDEQNKKLNHYVELKTSRIIENNSQVVSFEQKLFKAWCQCFLMGVTKIIYGFRDNNLILKNVELFNTEEIPILIKNNPLTNAATEKKINCTNALKWYGAVVDWLNTTVDKKDEIKSYRLKYDPVRKSFTLSETDSETNEKLRNGQLLTPEFTEWRQSLK 5bud A 1.99 BS04 MN A 3 E174 E223 E175 E224 3.6.1.- Q5AAT0 26101253 HMAKSLPLNSRSKTTALKQPRELFSYARDIDGKYVYDDPENSLSYYYLPDSTIDTGIDLQGGYSKFKKIPDEQNLADFNSLLKAIIKYETSEGKKISSDIITFREIMTKILSLPYNLTDPIDLYVVPFDGQLFIKSDDELDMKRRKEQEVRMKQTNTVERYDYMKRCEYVGYKFETIATIPKPWSQVSRSQIENRNKKVVNNYEQYLSVIRTGIGNVKLVLAGEIDCCWDYLPDEQNKKLNHYVELKTSRIIENNSQVVSFEQKLFKAWCQCFLMGVTKIIYGFRDNNLILKNVELFNTEEIPILIKNNPLTNAATEKKINCTNALKWYGAVVDWLNTTVDKKDEIKSYRLKYDPVRKSFTLSETDSETNEKLRNGQLLTPEFTEWRQSLK 5c0o E 2.62 BS01 SAM E 1 A74 T75 P76 T77 G101 T102 G103 S104 G105 G106 L107 E125 A126 H130 G152 K153 L154 E155 D170 L171 A58 T59 P60 T61 G85 T86 G87 S88 G89 G90 L91 E109 A110 H114 G136 K137 L138 E139 D154 L155 2.1.1.220 Q8GBB2 GPLLLKDRKGRAYLVFPKEGGVFVPHEALLEAGPGGVVELSVHRPTLEEYLLHMKRSATPTAPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELEEAAYDGVALDLMEPWKVLEKAALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVRLPVAHPRFQQVGHTAFLVALRRWKA 5c0o F 2.62 BS01 SAM F 1 T75 P76 T77 G101 G103 G105 G106 L107 A126 H130 K153 D170 L171 T62 P63 T64 G88 G90 G92 G93 L94 A113 H117 K140 D151 L152 2.1.1.220 Q8GBB2 PLLLKDRKGRAYLVFPKEGGVFSVPHEALLEAGPGGVVRTHLGEELSVHRPTLEEYLLHMKTPTAPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEAAYDGVALDLMEPWKVLAALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVRLPVAHPRFQQVGHTAFLVALRRWK 5c0o H 2.62 BS01 SAM H 1 A74 P76 T77 G101 T102 G103 S104 G105 G106 L107 E125 A126 R127 H130 K153 L154 D170 L171 A31 P33 T34 G58 T59 G60 S61 G62 G63 L64 E82 A83 R84 H87 K110 L111 D127 L128 2.1.1.220 Q8GBB2 HEALLEAGGVVRLSVHRPTLEEYLLHMKRSATPTAPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELEEAAYDGVALDLMEPWKVLEKAALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVRLPVAHPRFQQVGHTAFLVALRRWKA 5c4q A 1.93 BS01 BMF A 1 A30 M31 H33 Y34 V36 E40 V41 Y44 F86 N87 W93 A30 M31 H33 Y34 V36 E40 V41 Y44 F86 N87 W93 E9BU22 MDVSKRPREEFHKEQCLSFVKKLWAADTLAMFHYPVSATEVPGYYDVVDTPMDLSTIRKNIEQGKYRTDTEVENDVVLMLSNALDFNEKGSQWHDLAKQLKKRYLTLAQESGLSFDAD 5c4q B 1.93 BS01 BMF B 1 M31 V36 V41 N87 W93 M30 V35 V40 N86 W92 E9BU22 DVSKRPREEFHKEQCLSFVKKLWAADTLAMFHYPVSATEVPGYYDVVDTPMDLSTIRKNIEQGKYRTDTEVENDVVLMLSNALDFNEKGSQWHDLAKQLKKRYLTLAQESGLSF 5c56 A 2.69 BS01 III B 1 S629 N630 G631 M637 K681 H683 D684 I709 K739 L742 D754 D758 E759 L760 M761 D762 D764 S74 N75 G76 M82 K126 H128 D129 I154 K184 L187 D199 D203 E204 L205 M206 D207 D209 3.4.19.12 Q93009 PLGSEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFN 5c65 A 2.65 BS01 37X A 1 R91 P203 F204 R87 P199 F200 P11169 KVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c65 A 2.65 BS02 37X A 2 P8 A9 F12 A200 A201 F204 R228 P4 A5 F8 A196 A197 F200 R224 P11169 KVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c65 A 2.65 BS03 37X A 3 I76 F79 S80 L83 L100 L125 I72 F75 S76 L79 L96 L121 P11169 KVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c65 A 2.65 BS04 37X A 4 I96 L129 I92 L125 P11169 KVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c65 A 2.65 BS05 37X A 5 C106 F107 A114 S116 M119 C102 F103 A110 S112 M115 P11169 KVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c65 A 2.65 BS06 37X A 6 L46 A52 L62 V117 E118 I121 L42 A48 L58 V113 E114 I117 P11169 KVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c65 A 2.65 BS07 Y01 A 1 F79 V257 I274 L278 L282 S408 T411 V416 F75 V253 I270 L274 L278 S396 T399 V404 P11169 KVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c65 B 2.65 BS02 37X B 2 L83 I96 V126 L129 L76 I89 V119 L122 P11169 VTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c65 B 2.65 BS03 37X B 3 I76 S80 L83 L100 I69 S73 L76 L93 P11169 VTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c65 B 2.65 BS04 Y01 B 1 F79 V257 I274 L278 L282 S408 T411 F72 V247 I264 L268 L272 S391 T394 P11169 VTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFIQKTLTDKAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 5c7n A 1.75 BS01 BMF A 1 I652 F653 E655 V657 P658 V662 C704 Y707 N708 F714 I25 F26 E28 V30 P31 V35 C77 Y80 N81 F87 P55201 MQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5c92 A 2.10 BS01 CU1 A 1 F72 C73 Y120 Y334 H335 H423 F71 C72 Y119 Y333 H334 H422 E3QHV8 NVGKWGPMVKFPVVPVAVALVPETGNLLVWSSGWPNRWTTAGNGKTYTSLYNVNTGNISDAIVQNTQHDMFCPGTSLDADGRIIVTGGSSAAKTSVLDFKKGESSPWTPLSNMQISRGYQSSCTTSEGKIFVIGGSFSGAGTRNGEVYDPKANTWTKLAGCPVKPLVMQRGMFPDSHAWLWSWKNGSVLQAGPSKKMNWYDTKGTGSNTPAGLRGTDEDSMCGVSVMYDAVAGKIFTYGGGKGYTGYDSTSNAHILTLGEPGQAVQVQKLANGKYNRGFANAVVMPDGKIWVVGGMQKMWLFSDTTPQLTPELFDPATGSFTPTTPHTVPRNYHSTALLMADATIWSGGGGLCGANCKENHFDGQFWSPPYLFEADGVTPAKRPVIQSLSDTAVRAGAPITITMQDAGAYTFSMIRVSATTHTVNTDQRRIPLDGQDGGDGKSFTVNVPNDYGVAIPGYYMLFAMNEAGVPCVAQFFKVTL