2mps A BS01 III B 1 K51 L54 L57 G58 I61 M62 Q72 H73 V75 F91 V93 K94 H96 I99 Y100 K49 L52 L55 G56 I59 M60 Q70 H71 V73 F89 V91 K92 H94 I97 Y98 6.3.2.- Q00987 25591003 NTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVV 2msc B BS01 GDP B 1 A11 G13 V14 G15 K16 S17 A18 F28 V29 D30 P34 N116 K117 D119 S145 A146 K147 A11 G13 V14 G15 K16 S17 A18 F28 V29 D30 P34 N116 K117 D119 S145 A146 K147 A0A024RAV5 25941399 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKC 2msc B BS02 MG B 1 I36 E37 D57 T58 A59 I36 E37 D57 T58 A59 A0A024RAV5 25941399 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKC 2msd B BS01 GNP B 1 G13 G15 K16 S17 A18 F28 V29 D30 E31 Y32 D33 P34 T35 N116 K117 S145 A146 K147 G13 G15 K16 S17 A18 F28 V29 D30 E31 Y32 D33 P34 T35 N116 K117 S145 A146 K147 A0A024RAV5 25941399 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKC 2msd B BS02 MG B 1 S17 T35 D38 D57 S17 T35 D38 D57 A0A024RAV5 25941399 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKC 2mse B BS01 GNP B 1 G12 G13 G15 K16 S17 A18 F28 V29 D30 E31 Y32 D33 P34 T35 N116 A146 K147 G12 G13 G15 K16 S17 A18 F28 V29 D30 E31 Y32 D33 P34 T35 N116 A146 K147 A0A024RAV5 25941399 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKC 2mse B BS02 MG B 1 T35 D38 D57 T35 D38 D57 A0A024RAV5 25941399 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKC 2mzp C BS01 III I 1 A23 F27 L48 Q50 M81 M85 D88 A23 F27 L48 Q50 M81 M85 D88 P63316 25996354 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDS 2mzp C BS02 CA C 1 D65 D67 S69 T71 E76 D65 D67 S69 T71 E76 P63316 25996354 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDS 3x1w A 1.20 BS01 GDP A 1 G13 V14 G15 K16 S17 A18 F28 E30 N116 K117 D119 L120 S147 A148 K149 G13 V14 G15 K16 S17 A18 F28 E30 N116 K117 D119 L120 S147 A148 K149 Q62636 25935485 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWSNCAFLESSAKSKINVNEIFYDLVRQINR 3x1x A 1.00 BS01 GNP A 1 G12 G13 V14 G15 K16 S17 A18 F28 E30 K31 G60 N116 K117 D119 L120 S147 A148 K149 G12 G13 V14 G15 K16 S17 A18 F28 E30 K31 G60 N116 K117 D119 L120 S147 A148 K149 Q62636 25935485 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWSNCAFLESSAKSKINVNEIFYDLVRQIN 3x1y A 1.17 BS01 GNP A 1 G12 G13 V14 G15 K16 S17 A18 F28 E30 G60 Q63 N116 K117 D119 L120 S147 A148 K149 G12 G13 V14 G15 K16 S17 A18 F28 E30 G60 Q63 N116 K117 D119 L120 S147 A148 K149 Q62636 25935485 MREYKLVVVGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWSNCAFLESSAKSKINVNEIFYDLVRQIN 3x1z A 1.25 BS01 GNP A 1 G12 G13 V14 G15 K16 S17 A18 F28 V29 E30 K31 Y32 P34 T35 G60 N116 K117 D119 L120 S147 A148 K149 G12 G13 V14 G15 K16 S17 A18 F28 V29 E30 K31 Y32 P34 T35 G60 N116 K117 D119 L120 S147 A148 K149 Q62636 25935485 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFAAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWSNCAFLESSAKSKINVNEIFYDLVRQINR 4d5b A 1.70 BS01 ACX A 1 Q78 E80 Y83 E85 R166 W169 E205 N213 G256 N258 W303 Q66 E68 Y71 E73 R154 W157 E193 N201 G244 N246 W291 Q48391 AFDESFFSFGGHVGTSVEYEDKVTRGFNNTDKKEKTITNEVFNFFYNNPQWNFMGFYSFKIENREQKEPGYYENEDGIKQLFSLNKGHDLGNGWATGLIYELEYTRSKVYSPDVSGLRKNLAEHSIRPYLTYWNNDYNMGFYSNLEYLLSKEDRNAWGKRQEQGYSALFKPYKRFGNWEVGVEFYYQIKTNDEKQPDGTINEKSDFNERYIEPIVQYSFDDAGTLYTRVRVGKNETKNTDRSGGGNAGINYFKDIRKATVGYEQSIGESWVAKAEYEYANEVEKKSRLSGWEARNKSELTQHTFYAQALYRF 4d5b A 1.70 BS02 ACX A 2 H24 F57 M66 F68 N97 E113 R139 E275 K285 Y317 Q319 H12 F45 M54 F56 N85 E101 R127 E263 K273 Y305 Q307 Q48391 AFDESFFSFGGHVGTSVEYEDKVTRGFNNTDKKEKTITNEVFNFFYNNPQWNFMGFYSFKIENREQKEPGYYENEDGIKQLFSLNKGHDLGNGWATGLIYELEYTRSKVYSPDVSGLRKNLAEHSIRPYLTYWNNDYNMGFYSNLEYLLSKEDRNAWGKRQEQGYSALFKPYKRFGNWEVGVEFYYQIKTNDEKQPDGTINEKSDFNERYIEPIVQYSFDDAGTLYTRVRVGKNETKNTDRSGGGNAGINYFKDIRKATVGYEQSIGESWVAKAEYEYANEVEKKSRLSGWEARNKSELTQHTFYAQALYRF 4d5b B 1.70 BS02 ACX B 2 H24 N55 F57 M66 F68 N97 E113 R139 E275 K285 Y317 Q319 L321 H9 N40 F42 M51 F53 N82 E98 R124 E260 K270 Y302 Q304 L306 Q48391 ESFFSFGGHVGTSVEYEDKVTRGFNNTDKKEKTITNEVFNFFYNNPQWNFMGFYSFKIENREQKEPGYYENEDGIKQLFSLNKGHDLGNGWATGLIYELEYTRSKVYSPDVSGLRKNLAEHSIRPYLTYWNNDYNMGFYSNLEYLLSKEDRNAWGKRQEQGYSALFKPYKRFGNWEVGVEFYYQIKTNDEKQPDGTINEKSDFNERYIEPIVQYSFDDAGTLYTRVRVGKNETKNTDRSGGGNAGINYFKDIRKATVGYEQSIGESWVAKAEYEYANEVEKKSRLSGWEARNKSELTQHTFYAQALYRF 4d5d A 1.90 BS02 BCD A 1 H24 F57 Y154 K182 R186 E191 E275 K285 Q319 L321 R323 H11 F44 Y141 K169 R173 E178 E262 K272 Q306 L308 R310 Q48391 FDESFFSFGGHVGTSVEYEDKVTRGFNNTDKKEKTITNEVFNFFYNNPQWNFMGFYSFKIENREQKEPGYYENEDGIKQLFSLNKGHDLGNGWATGLIYELEYTRSKVYSPDVSGLRKNLAEHSIRPYLTYWNNDYNMGFYSNLEYLLSKEDRNAWGKRQEQGYSALFKPYKRFGNWEVGVEFYYQIKTNDEKQPDGTINEKSDFNERYIEPIVQYSFDDAGTLYTRVRVGKNETKNTDRSGGGNAGINYFKDIRKATVGYEQSIGESWVAKAEYEYANEVEKKSRLSGWEARNKSELTQHTFYAQALYRF 4pkm A 1.65 BS01 GLY A 1 A90 K91 K92 A86 K87 K88 A7IZR5 25957471 AILDLKSLVLNAINYWGPKNNNGIQGGDFGYPISEKQIDTSIITSTHPRLIPHDLTIPQNLETIFTTTQVLTNNTDLQQSQTVSFAKKTTTTTSTSTTNGWTEGGKISDTLEEKVSVSIPFIGEGGGKNSTTIEANFAHNSSTTTFQQASTDIEWNISQPVLVPPRKQVVATLVIMGGNFTIPMDLMTTIDSTEHYSGYPILTWISSPDNSYNGPFMSWYFANWPNLPSGFGPLNSDNTVTYTGSVVSQVSAGVYATVRFDQYDIHNLRTIEKTWYARHATLHNGKKISINNVTEMAPTSPIKTN 4pkm A 1.65 BS02 GLY A 2 N295 M300 P302 T303 N291 M296 P298 T299 A7IZR5 25957471 AILDLKSLVLNAINYWGPKNNNGIQGGDFGYPISEKQIDTSIITSTHPRLIPHDLTIPQNLETIFTTTQVLTNNTDLQQSQTVSFAKKTTTTTSTSTTNGWTEGGKISDTLEEKVSVSIPFIGEGGGKNSTTIEANFAHNSSTTTFQQASTDIEWNISQPVLVPPRKQVVATLVIMGGNFTIPMDLMTTIDSTEHYSGYPILTWISSPDNSYNGPFMSWYFANWPNLPSGFGPLNSDNTVTYTGSVVSQVSAGVYATVRFDQYDIHNLRTIEKTWYARHATLHNGKKISINNVTEMAPTSPIKTN 4pkm A 1.65 BS03 GLY A 3 H51 R53 H47 R49 A7IZR5 25957471 AILDLKSLVLNAINYWGPKNNNGIQGGDFGYPISEKQIDTSIITSTHPRLIPHDLTIPQNLETIFTTTQVLTNNTDLQQSQTVSFAKKTTTTTSTSTTNGWTEGGKISDTLEEKVSVSIPFIGEGGGKNSTTIEANFAHNSSTTTFQQASTDIEWNISQPVLVPPRKQVVATLVIMGGNFTIPMDLMTTIDSTEHYSGYPILTWISSPDNSYNGPFMSWYFANWPNLPSGFGPLNSDNTVTYTGSVVSQVSAGVYATVRFDQYDIHNLRTIEKTWYARHATLHNGKKISINNVTEMAPTSPIKTN 4pw3 A 2.35 BS01 MSS A 1 Y76 I77 R78 N79 N80 L125 C127 S128 G186 E188 V201 H228 R233 G241 V242 N244 I245 K246 Y247 Y267 Y42 I43 R44 N45 N46 L91 C93 S94 G152 E154 V167 H194 R199 G207 V208 N210 I211 K212 Y213 Y233 1.8.3.1 Q92M24 KPLPDYVAWKDADALIVHSDKTLETKRSEFGTSIITPEEKLYIRNNVNTPPESILADRDGWKVEISGVKEPRTLTVAELKTLGLVTAATVLQCSGNGRKYFKDQLTGDQKMSGTPWTVGAAGCVIWSGVPLKAVVDALGGPAEGARFITGTGGEELPAGLDPKLLVVERSVPISNLDNVILAWEMNGRPLSLAHGGPLRMVVPGYSGVNNIKYVKAVAMTEVETDAKIQKTSYRVHALGEKGSPDQPSVWEQPVKSWITTPHEAAKAGQVQIAGVAFGGMNACKSVEVSVDGGQTWQEAEFIGPDLGRFAWRVFALSADLARGTYTLVSRATDTEGNVQPEETEMNGAGYGHNGWRAPAVKLTVA 4pw9 A 2.49 BS02 HEC B 1 R78 N80 S146 G147 R42 N44 S110 G111 1.8.3.1 Q92M24 LPDYVAWKDADALIVHSDKTLETKRSEFGTSIITPEEKLYIRNNVNTPPESILADRDGWKVEISGVKEPRTLTVAELKTLGLVTAATVLQCSGNGRKYFKDQLTGDQKMSGTPWTVGAAGCVIWSGVPLKAVVDALGGPAEGARFITGTGGEELPAGLDPKLLVVERSVPISNLDNVILAWEMNGRPLSLAHGGPLRMVVPGYSGVNNIKYVKAVAMTEVETDAKIQKTSYRVHALGEKGSPDQPSVWEQPVKSWITTPHEAAKAGQVQIAGVAFGGMNACKSVEVSVDGGQTWQEAEFIGPDLGRFAWRVFALSADLARGTYTLVSRATDTEGNVQPEETEMNGAGYGHNGWRAPAVKLTVA 4pw9 B 2.49 BS01 HEC B 1 P45 Q46 C47 C50 H51 V62 G63 P64 L69 R75 V76 A79 V80 I84 P86 M87 P17 Q18 C19 C22 H23 V34 G35 P36 L41 R47 V48 A51 V52 I56 P58 M59 Q92M25 EDKLALGREIFLERSEPQCALCHTLADAEAVGEVGPNLDELKPDAERVNTAVTNGIGPMPANEILTDEEIEAVALYVSTVAGK 4pwa A 2.19 BS01 HEC A 1 P45 Q46 C47 C50 H51 G63 P64 L66 L69 R75 V76 V80 I84 G85 P86 M87 P17 Q18 C19 C22 H23 G35 P36 L38 L41 R47 V48 V52 I56 G57 P58 M59 Q92M25 EDKLALGREIFLERSEPQCALCHTLADAEAVGEVGPNLDELKPDAERVNTAVTNGIGPMPANEILTDEEIEAVALYVSTVAGKAKN 4pwa C 2.19 BS01 HEC C 1 P45 Q46 C47 C50 H51 P64 L69 R75 V76 A79 V80 I84 G85 P86 M87 P88 P19 Q20 C21 C24 H25 P38 L43 R49 V50 A53 V54 I58 G59 P60 M61 P62 Q92M25 MEEDKLALGREIFLERSEPQCALCHTLADAEAVGEVGPNLDELKPDAERVNTAVTNGIGPMPANEILTDEEIEAVALYVSTVAGK 4pwa D 2.19 BS01 HEC D 1 P45 C47 C50 H51 G63 P64 L69 R75 V76 V80 I84 G85 P86 M87 P18 C20 C23 H24 G36 P37 L42 R48 V49 V53 I57 G58 P59 M60 Q92M25 EEDKLALGREIFLERSEPQCALCHTLADAEAVGEVGPNLDELKPDAERVNTAVTNGIGPMPANEILTDEEIEAVALYVSTVAGKAKN 4qho A 2.37 BS02 NKG A 1 R96 Y106 Y108 L109 L203 N205 V228 H231 D233 E234 V244 Y295 H307 V309 R316 S318 T320 R322 R69 Y79 Y81 L82 L151 N153 V176 H179 D181 E182 V192 Y232 H244 V246 R253 S255 T257 R259 1.14.11.- Q9C0B1 GSHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKADEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCELEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAK 4qhy A 3.29 BS01 MG A 1 T23 T46 D93 T22 T45 D92 Q980A5 AWPKVQPEVNIGVVGHVDFGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVAVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4qxt A 1.58 BS01 III Q 1 D31 D32 Y99 G100 V101 A102 D31 D32 Y99 G100 V101 A102 25965408 QVQLQQSGDELVKPGASVKLSCTVSGFNIKDDFIHWMKQRPEQGLEWIGRIDPANGYTKYAPKFQDKATMTADTSSNTAYLQLSSLASEDAAVYYCATYGVAYWGQGTLVTVSA 4qxt B 1.58 BS01 III Q 1 H31 D34 Y36 N38 L50 Y53 A54 L58 E59 S60 T95 N96 Y100 H31 D34 Y36 N38 L50 Y53 A54 L58 E59 S60 T95 N96 Y100 25965408 DIVLTQSPASLAVSLGQRATISCKASQSVDHDGDSYMNWFQQKPGQSPKLLIYAASNLESGIPARFSGSGSGTDFTLNIHPVEEEDAATYYCQQTNEDPYTFGGGTKLEIK 4qy8 A 1.35 BS01 III Q 1 D31 D32 F33 H35 R50 D52 N55 Y57 Y99 G100 V101 A102 D31 D32 F33 H35 R50 D52 N55 Y57 Y99 G100 V101 A102 25965408 QVQLQQSGDELVKPGASVKLSCTVSGFNIKDDFIHWMKQRPEQGLEWIGRIDPANGYTKYAPKFQDKATMTADTSSNTAYLQLSSLASEDAAVYYCATYGVAYWGQGTLVTVSA 4qyo A 1.21 BS01 III Q 1 D31 D32 F33 H35 Y99 G100 V101 D31 D32 F33 H35 Y99 G100 V101 25965408 QVQLQQSGDELVKPGASVKLSCTVSGFNIKDDFIHWMKQRPEQGLEWIGRIDPANGYTKYAPKFQDKATMTADTSSNTAYLQLSSLASEDAAVYYCATYGVAYWGQGTLVTVSA 4qyo B 1.21 BS01 III Q 1 H31 D34 Y36 N38 Y53 A54 E59 T95 N96 E97 Y100 H31 D34 Y36 N38 Y53 A54 E59 T95 N96 E97 Y100 25965408 DIVLTQSPASLAVSLGQRATISCKASQSVDHDGDSYMNWFQQKPGQSPKLLIYAASNLESGIPARFSGSGSGTDFTLNIHPVEEEDAATYYCQQTNEDPYTFGGGTKLEIK 4r3s A 1.70 BS01 III Q 1 D31 D32 F33 Y99 G100 V101 A102 D31 D32 F33 Y99 G100 V101 A102 25965408 QVQLQQSGDELVKPGASVKLSCTVSGFNIKDDFIHWMKQRPEQGLEWIGRIDPANGYTKYAPKFQDKATMTADTSSNTAYLQLSSLASEDAAVYYCATYGVAYWGQGTLVTVSA 4r3s B 1.70 BS01 III Q 1 H31 Y36 N38 Y53 N57 E59 T95 N96 E97 Y100 H31 Y36 N38 Y53 N57 E59 T95 N96 E97 Y100 25965408 DIVLTQSPASLAVSLGQRATISCKASQSVDHDGDSYMNWFQQKPGQSPKLLIYAASNLESGIPARFSGSGSGTDFTLNIHPVEEEDAATYYCQQTNEDPYTFGGGTKLEIK 4rvk A 1.85 BS01 3XK A 1 L15 A36 K38 V68 L84 E85 Y86 C87 G90 E91 L137 D148 L13 A34 K36 V59 L75 E76 Y77 C78 G81 E82 L128 D139 2.7.11.1 O14757 25988399 VPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKNIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGA 4rvm A 1.86 BS01 3X7 A 1 T14 L15 A36 K38 V68 L84 E85 Y86 C87 L137 D148 T12 L13 A34 K36 V59 L75 E76 Y77 C78 L128 D139 2.7.11.1 O14757 25988399 VPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKNIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGA 4rw3 A 1.72 BS02 IPD A 1 H12 E32 D34 H48 D92 K94 S167 Y223 W225 M245 H11 E31 D33 H47 D91 K93 S166 Y222 W224 M244 3.1.4.4 P0CE82 25961401 GNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK 4rw3 A 1.72 BS03 OCA A 1 A259 K263 A258 K262 3.1.4.4 P0CE82 25961401 GNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK 4rw3 A 1.72 BS04 SHV A 1 G176 Y179 I184 T185 F218 G175 Y178 I183 T184 F217 3.1.4.4 P0CE82 25961401 GNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK 4rw3 A 1.72 BS05 TDA A 1 N138 Y140 K181 N137 Y139 K180 3.1.4.4 P0CE82 25961401 GNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK 4rw5 A 1.64 BS03 OCA A 1 E32 D34 H48 D92 K94 S133 S167 Y223 W225 M245 E31 D33 H47 D91 K93 S132 S166 Y222 W224 M244 3.1.4.4 P0CE82 25961401 GNRRPIWIMGAMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFK 4s10 C 2.61 BS01 CA C 1 G186 D187 N206 E209 D259 G28 D29 N48 E51 D101 P06396 25601851 VQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERDGDARVHVSEEGTEPEAMLQVLGPKPALPAGTED 4s10 D 2.61 BS01 CA D 1 G186 D187 E209 D259 G27 D28 E50 D100 P06396 25601851 QRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERDGDARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA 4tkc A 1.29 BS01 BMA A 1 Q63 D65 N67 Y71 A77 H80 N84 Q63 D65 N67 Y71 A77 H80 N84 I7H471 SYVHPYGSTLPENGVIGRGYALISDSGRVEFRVTDEGNIQLFLDDSRKLWSVDGKNASFVKMQTDGNCVGYDPNGTAVWHTATNGDDHPYNLVCQNDGNLVVYAKGGKAVWHTNTAVV 4tkc A 1.29 BS02 MAN A 1 Q95 D97 N99 Y103 A109 Q95 D97 N99 Y103 A109 I7H471 SYVHPYGSTLPENGVIGRGYALISDSGRVEFRVTDEGNIQLFLDDSRKLWSVDGKNASFVKMQTDGNCVGYDPNGTAVWHTATNGDDHPYNLVCQNDGNLVVYAKGGKAVWHTNTAVV 4tm7 A 1.39 BS01 CU1 A 1 H67 H104 H66 H103 3.1.1.31 A0QWX6 SDTVIERHADTAALVAAAGDRLVDAISSAIGERGQATIVLTGGGTGIGLLKRVRERSGEIDWSKVHIYWGDERFVPQDDDERNDKQAREALLDHIGIPPVNVHAMAASDGEFGDDLEAAAAGYAQLLSADFDSSVPGFDVHLLGMGGEGHVNSLFPDTDAVRETERLVVGVSDSPKPPPRRITLTLPAVQNSREVWLVVSGEAKADAVAAAVGGADPVDIPAAGAVGRERTVWLVDEAAAAKL 4tm7 A 1.39 BS02 CU A 1 D25 R57 D24 R56 3.1.1.31 A0QWX6 SDTVIERHADTAALVAAAGDRLVDAISSAIGERGQATIVLTGGGTGIGLLKRVRERSGEIDWSKVHIYWGDERFVPQDDDERNDKQAREALLDHIGIPPVNVHAMAASDGEFGDDLEAAAAGYAQLLSADFDSSVPGFDVHLLGMGGEGHVNSLFPDTDAVRETERLVVGVSDSPKPPPRRITLTLPAVQNSREVWLVVSGEAKADAVAAAVGGADPVDIPAAGAVGRERTVWLVDEAAAAKL 4tm7 A 1.39 BS03 CU A 2 H151 N153 H150 N152 3.1.1.31 A0QWX6 SDTVIERHADTAALVAAAGDRLVDAISSAIGERGQATIVLTGGGTGIGLLKRVRERSGEIDWSKVHIYWGDERFVPQDDDERNDKQAREALLDHIGIPPVNVHAMAASDGEFGDDLEAAAAGYAQLLSADFDSSVPGFDVHLLGMGGEGHVNSLFPDTDAVRETERLVVGVSDSPKPPPRRITLTLPAVQNSREVWLVVSGEAKADAVAAAVGGADPVDIPAAGAVGRERTVWLVDEAAAAKL 4tqk A 2.10 BS01 NAG A 1 N104 G110 W112 H117 G136 E137 N103 G109 W111 H116 G135 E136 H6CS64 TSNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqk A 2.10 BS02 NAG A 2 N47 G53 G54 W55 H60 G79 N80 N46 G52 G53 W54 H59 G78 N79 H6CS64 TSNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqk A 2.10 BS03 NAG A 3 D160 G166 G167 W168 H173 G192 D193 F197 D159 G165 G166 W167 H172 G191 D192 F196 H6CS64 TSNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqk A 2.10 BS04 NAG A 4 N216 G222 W224 G248 K249 W253 N215 G221 W223 G247 K248 W252 H6CS64 TSNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqk A 2.10 BS05 NAG A 5 D272 K277 G278 W279 G303 N304 Y308 D271 K276 G277 W278 G302 N303 Y307 H6CS64 TSNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqk A 2.10 BS06 NAG A 6 D327 Q332 G333 W334 H339 G358 E359 D326 Q331 G332 W333 H338 G357 E358 H6CS64 TSNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqk B 2.10 BS01 NAG B 1 N47 G53 G54 W55 H60 G79 N80 Y84 N46 G52 G53 W54 H59 G78 N79 Y83 H6CS64 TSNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqk B 2.10 BS03 NAG B 3 D160 G166 W168 H173 G192 D193 F197 D159 G165 W167 H172 G191 D192 F196 H6CS64 TSNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqk B 2.10 BS04 NAG B 4 D272 K277 G278 W279 H284 G303 N304 D271 K276 G277 W278 H283 G302 N303 H6CS64 TSNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqm A 2.00 BS01 NAG A 1 N47 G53 W55 H60 G79 N80 Y84 N45 G51 W53 H58 G77 N78 Y82 H6CS64 SNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqm A 2.00 BS02 GAL A 1 N80 A81 N78 A79 H6CS64 SNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqm A 2.00 BS04 GAL A 2 E137 K138 E135 K136 H6CS64 SNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqm A 2.00 BS05 NAG A 3 E137 K138 D164 E135 K136 D162 H6CS64 SNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqm A 2.00 BS07 GAL A 3 D193 K194 D191 K192 H6CS64 SNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqm A 2.00 BS08 NAG A 5 D193 K194 D220 D191 K192 D218 H6CS64 SNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqm A 2.00 BS10 GAL A 4 K249 A250 K247 A248 H6CS64 SNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqm A 2.00 BS11 NAG A 7 D272 K277 G278 W279 G303 N304 D270 K275 G276 W277 G301 N302 H6CS64 SNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tqm A 2.00 BS12 NAG A 8 D327 Q332 G333 W334 H339 G358 E359 L363 D325 Q330 G331 W332 H337 G356 E357 L361 H6CS64 SNVITQDLPIPVASRGFADIVGFGLDGVVIGRNAVNLQPFLAVKNFAQNAGGWLTTKHVRLIADTTGTGKGDIVGFGNAGVYVSVNNGKNTFADPPKMVIANFGYDAGGWRVEKHLRYLADIRKTGRADIIGFGEKGVLVSRNNGGLNFGPATLVLKDFGYDAGGWRLDRHLRFLADVTGNGHLDIVGFGDKHVFISRNNGDGTFAPAKSVIDNFCIDAGGWKIGDHPRFVADLTGDGTADIIGCGKAGCWVALNNGGGVFGQVKLVINDFGTDKGWQAAKHPRFIADLTGNGRGDVVGFGNAGVYVALNNGDGTFQSAKLVLKDFGVQQGWTVSKHRRFVVDLTGDGCADIIGFGEKETLVSYNDGKGNFGPVKALTNDFSFSGGKWAPETTVCWMANLDS 4tzh A 1.39 BS01 ZN A 1 H71 D94 H47 D70 PKEVIIHKNLSDALKTPNEVQILDLSRNQLTILPKEIEQLVNLESLHLRDNELTTLPEEIGILKNLKYLDISRNQISNFPKEIQKLKNLEVLFLNGNSLSNLPEEIGELEKLGILYLNNNQLTTLPKEIGQLENLVSLSLSSNKLTSIPDELGQLKKLRILNLWDNPTLTTPERNIRKLFRNQEITIEIS 4tzh A 1.39 BS02 ZN A 2 K91 E114 K67 E90 PKEVIIHKNLSDALKTPNEVQILDLSRNQLTILPKEIEQLVNLESLHLRDNELTTLPEEIGILKNLKYLDISRNQISNFPKEIQKLKNLEVLFLNGNSLSNLPEEIGELEKLGILYLNNNQLTTLPKEIGQLENLVSLSLSSNKLTSIPDELGQLKKLRILNLWDNPTLTTPERNIRKLFRNQEITIEIS 4tzh A 1.39 BS03 ZN A 3 E82 E106 E58 E82 PKEVIIHKNLSDALKTPNEVQILDLSRNQLTILPKEIEQLVNLESLHLRDNELTTLPEEIGILKNLKYLDISRNQISNFPKEIQKLKNLEVLFLNGNSLSNLPEEIGELEKLGILYLNNNQLTTLPKEIGQLENLVSLSLSSNKLTSIPDELGQLKKLRILNLWDNPTLTTPERNIRKLFRNQEITIEIS 4u06 A 1.90 BS01 ZN A 1 Y144 H146 D167 Y111 H113 D134 Q72U33 TYRDLTKALQNPLEVRVLDLSRQELKTLPIEIGKLKNLQRLYLHYNQLTVLPQEIEQLKNLQLLYLRSNRLTTLPKEIEQLKNLQVLDLGSNQLTVLPQEIGQLKNLQLLYLHSNRLTTLSKDIEQLQNLKSLDLSNNQLTTLPNEIEQLKNLKSLYLSENQFATFPKEIGQLQNLKVLFLNNNQITILPNEIAKLKKLQYLYLSDNQLITLPKEIEQLKNLQTLDLSYNQLILPKEVGQLENLQTLDLRNNQLKTLPKEIEQLKNLQTLFLSNNQLTILPQEIGKLKNLLWLSLVYNQLTTLPNEIEQLKNLQTLYLNNNQFSSQEKKRIRKLLPKCQIYFD 4u06 A 1.90 BS02 ZN A 2 K155 N178 E179 K122 N145 E146 Q72U33 TYRDLTKALQNPLEVRVLDLSRQELKTLPIEIGKLKNLQRLYLHYNQLTVLPQEIEQLKNLQLLYLRSNRLTTLPKEIEQLKNLQVLDLGSNQLTVLPQEIGQLKNLQLLYLHSNRLTTLSKDIEQLQNLKSLDLSNNQLTTLPNEIEQLKNLKSLYLSENQFATFPKEIGQLQNLKVLFLNNNQITILPNEIAKLKKLQYLYLSDNQLITLPKEIEQLKNLQTLDLSYNQLILPKEVGQLENLQTLDLRNNQLKTLPKEIEQLKNLQTLFLSNNQLTILPQEIGKLKNLLWLSLVYNQLTTLPNEIEQLKNLQTLYLNNNQFSSQEKKRIRKLLPKCQIYFD 4u06 A 1.90 BS03 ZN A 3 H146 E193 H113 E160 Q72U33 TYRDLTKALQNPLEVRVLDLSRQELKTLPIEIGKLKNLQRLYLHYNQLTVLPQEIEQLKNLQLLYLRSNRLTTLPKEIEQLKNLQVLDLGSNQLTVLPQEIGQLKNLQLLYLHSNRLTTLSKDIEQLQNLKSLDLSNNQLTTLPNEIEQLKNLKSLYLSENQFATFPKEIGQLQNLKVLFLNNNQITILPNEIAKLKKLQYLYLSDNQLITLPKEIEQLKNLQTLDLSYNQLILPKEVGQLENLQTLDLRNNQLKTLPKEIEQLKNLQTLFLSNNQLTILPQEIGKLKNLLWLSLVYNQLTTLPNEIEQLKNLQTLYLNNNQFSSQEKKRIRKLLPKCQIYFD 4u08 A 1.95 BS01 ZN A 1 H196 H219 H162 H185 Q72TC3 QTYYRNITEALKNPQNVRILNLSGSKLTTLPGEIGKLQNLQLLNLDDNQLIALPKEIGKLQNLQQLHLSKNQLMALPEEIGQLQNLQKLKLYENQLTAIPKEIGQLQNLQELNLAHNQLATLPEDIEQLQRLQTLYLGHNQFNSILKEIGQLQNLESLGLDHNQLNVLPKEIGQLRNLESLGLDHNQLNVLPKEIGQLQNLQILHLRNNQLTTLPKEIGQLQNLQKLLLNKNKLTTLPKEIGQLQNLQKLKLYENQLTTLPKEIGQLQNLQELDLDGNQLTTLPENIGQLQRLQTLYLGNNQLNFLPKEIGQLRNLESLDLEHNQLNALPKEIGKLQKLQTLNLKYNQLATLPEEIKQLKNLKKLYLHNNPLPSEKIARIRKLLPQCIIYF 4u08 A 1.95 BS02 CA A 1 E190 E213 E156 E179 Q72TC3 QTYYRNITEALKNPQNVRILNLSGSKLTTLPGEIGKLQNLQLLNLDDNQLIALPKEIGKLQNLQQLHLSKNQLMALPEEIGQLQNLQKLKLYENQLTAIPKEIGQLQNLQELNLAHNQLATLPEDIEQLQRLQTLYLGHNQFNSILKEIGQLQNLESLGLDHNQLNVLPKEIGQLRNLESLGLDHNQLNVLPKEIGQLQNLQILHLRNNQLTTLPKEIGQLQNLQKLLLNKNKLTTLPKEIGQLQNLQKLKLYENQLTTLPKEIGQLQNLQELDLDGNQLTTLPENIGQLQRLQTLYLGNNQLNFLPKEIGQLRNLESLDLEHNQLNALPKEIGKLQKLQTLNLKYNQLATLPEEIKQLKNLKKLYLHNNPLPSEKIARIRKLLPQCIIYF 4u08 B 1.95 BS02 ZN B 2 E127 H150 E93 H116 Q72TC3 QTYYRNITEALKNPQNVRILNLSGSKLTTLPGEIGKLQNLQLLNLDDNQLIALPKEIGKLQNLQQLHLSKNQLMALPEEIGQLQNLQKLKLYENQLTAIPKEIGQLQNLQELNLAHNQLATLPEDIEQLQRLQTLYLGHNQFNSILKEIGQLQNLESLGLDHNQLNVLPKEIGQLRNLESLGLDHNQLNVLPKEIGQLQNLQILHLRNNQLTTLPKEIGQLQNLQKLLLNKNKLTTLPKEIGQLQNLQKLKLYENQLTTLPKEIGQLQNLQELDLDGNQLTTLPENIGQLQRLQTLYLGNNQLNFLPKEIGQLRNLESLDLEHNQLNALPKEIGKLQKLQTLNLKYNQLATLPEEIKQLKNLKKLYLHNNPLPSEKIARIRKLLPQCIIYF 4u08 B 1.95 BS03 ZN B 3 D80 H101 D46 H67 Q72TC3 QTYYRNITEALKNPQNVRILNLSGSKLTTLPGEIGKLQNLQLLNLDDNQLIALPKEIGKLQNLQQLHLSKNQLMALPEEIGQLQNLQKLKLYENQLTAIPKEIGQLQNLQELNLAHNQLATLPEDIEQLQRLQTLYLGHNQFNSILKEIGQLQNLESLGLDHNQLNVLPKEIGQLRNLESLGLDHNQLNVLPKEIGQLQNLQILHLRNNQLTTLPKEIGQLQNLQKLLLNKNKLTTLPKEIGQLQNLQKLKLYENQLTTLPKEIGQLQNLQELDLDGNQLTTLPENIGQLQRLQTLYLGNNQLNFLPKEIGQLRNLESLDLEHNQLNALPKEIGKLQKLQTLNLKYNQLATLPEEIKQLKNLKKLYLHNNPLPSEKIARIRKLLPQCIIYF 4u09 A 1.95 BS01 ZN A 1 E369 E392 E344 E367 Q72NS0 IQKPYKNLAKALQNPADVRNLDLSFQGLKTLPNKIGQLKNLQKLDLGGNEPTILSKEIWQLKDLQKLNLNNNKLTVLPKEIGQLQNLQELSLHSNELVNLPKEIGQFKNLQKLNLDNNKLTVLPKEIGQLQNLQELSLLSNKLISLPTEIEQLKSLKNLDLNHNEFTTVSKEVMLLETLENLDLRSNKLKTIPKEIRQLKSLKVLMLTGNQLTSLPKEIEQLQNLKTLNLGENRFQIFPVEILELKNLLELNLYYNQLVEFPKEVGQLKSLKYLSLYHNQITTLPVEVTQLPDLQELHLSGNKITILPKEILQLKNLEWLSLSNNKLNALPKEIGQLKKLQRLELGNNQLTTLPKEIEQLKNLQRLELDSNPISPKEKERIRKLLPKCEIDF 4u09 B 1.95 BS01 ZN B 1 S162 D185 S137 D160 Q72NS0 IQKPYKNLAKALQNPADVRNLDLSFQGLKTLPNKIGQLKNLQKLDLGGNEPTILSKEIWQLKDLQKLNLNNNKLTVLPKEIGQLQNLQELSLHSNELVNLPKEIGQFKNLQKLNLDNNKLTVLPKEIGQLQNLQELSLLSNKLISLPTEIEQLKSLKNLDLNHNEFTTVSKEVMLLETLENLDLRSNKLKTIPKEIRQLKSLKVLMLTGNQLTSLPKEIEQLQNLKTLNLGENRFQIFPVEILELKNLLELNLYYNQLVEFPKEVGQLKSLKYLSLYHNQITTLPVEVTQLPDLQELHLSGNKITILPKEILQLKNLEWLSLSNNKLNALPKEIGQLKKLQRLELGNNQLTTLPKEIEQLKNLQRLELDSNPISPKEKERIRKLLPKCEIDFEGGG 4u1r A 2.80 BS01 ATP A 1 S32 G33 G34 Y64 R97 C98 F101 R102 G127 D128 G129 S130 G133 S8 G9 G10 Y40 R73 C74 F77 R78 G103 D104 G105 S106 G109 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4u1r C 2.80 BS01 ATP C 1 S32 G34 Y64 R97 C98 F101 R102 G127 D128 G129 S130 G133 L136 S8 G10 Y40 R73 C74 F77 R78 G103 D104 G105 S106 G109 L112 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEAFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4u1r D 2.80 BS01 ATP D 1 G33 Y64 R97 C98 F101 R102 G127 D128 G129 S130 G133 D175 D177 G9 Y40 R73 C74 F77 R78 G103 D104 G105 S106 G109 D151 D153 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4ue0 B 1.17 BS01 CO3 B 1 R425 A469 D470 L473 R6 A50 D51 L54 Q997H2 25994880 TRQGSRVVGFMDFIIALGWQIIPSNIRYIYILNCSQFMPTSDVTTIYFQADSGLESIFVMDSPFYASCTQQLPDKTIKTYGVTISKKQSIISINFSSSLEPNIMVSAWTASITRT 4uia A 2.18 BS03 FH9 A 1 H69 R71 R127 N144 R145 Y198 S207 L247 Y248 D255 F279 H64 R66 R122 N139 R140 Y194 S203 L243 Y244 D251 F275 3.4.17.2,3.4.17.20 P09955 25990761 GHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGIHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLSIHSYSQHIVYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTLYLAPGGGDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHLY 4uib A 1.94 BS03 GWX A 1 H69 R71 R127 N144 R145 E163 T164 Y198 V203 S207 L247 Y248 D255 E270 F279 H64 R66 R122 N139 R140 E158 T159 Y194 V199 S203 L243 Y244 D251 E266 F275 3.4.17.2 P09955 25990761 GHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGIHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLSIHSYSQHIVYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTLYLAPGGGDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHLY 4w8l A 1.76 BS01 CA A 1 D498 D500 D502 D504 D507 D159 D161 D163 D165 D168 3.2.1.8 O69230 26001782 NIPDLAKKLGSSYALGAAIDQTALDPKDPHSELLTKHFNSITAGNFMKMDAMQPTEGKFVWSEADKLVNFAAANNMQVRGHTLLWHSQVPDWFFTDPNDPSKPATREQLMQRMKTHIQTIVSRYKGKVHTWDVVNEVISDGGGLRNQASGSKWRDIIGDVDGDGDDSDYIELAFRYAREADPDAVLVINDYGIEGSVSKMNDMVKLVEKLLAKGTPIDAIGFQMHVSMYGPDIKQIREAFNRAAALGVHIQVTELDMSIYSGNSEQEKPVTDEMMLEQAYRYRALFDLFKEFDDRGVMDSVTLWGLADDGTWLDDFPVKGRKDAPLLFDRKLKAKPAYWALVDPSTLPVYRN 4wzx A 1.39 BS01 III E 1 L52 Q56 L59 G60 L63 L66 A67 R75 H79 V82 Q83 M86 A87 A89 E90 K93 L41 Q45 L48 G49 L52 L55 A56 R64 H68 V71 Q72 M75 A76 A78 E79 K82 2.7.11.1 Q6PHR2 TSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKM 4wzx A 1.39 BS02 CO A 1 H57 E61 H46 E50 2.7.11.1 Q6PHR2 TSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKM 4x3h A 2.40 BS01 III B 1 F206 L209 D210 T211 Q212 I213 F214 E215 F220 H223 L224 H245 M246 N247 F271 Y274 S275 F8 L11 D12 T13 Q14 I15 F16 E17 F22 H25 L26 H47 M48 N49 F73 Y76 S77 Q63053 25864631 GPLGSPEFPGLDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEG 4x3i A 1.80 BS01 III B 1 D210 T211 Q212 I213 F214 E215 P217 F220 H223 L224 Y227 N244 H245 N247 A250 F271 D5 T6 Q7 I8 F9 E10 P12 F15 H18 L19 Y22 N39 H40 N42 A45 F66 Q63053 25864631 FPGLDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEG 4xba A 1.50 BS01 GMP A 1 L38 Y41 N50 R62 D63 M64 F65 K67 H71 M143 H147 H149 L6 Y9 N18 R30 D31 M32 F33 K35 H39 M111 H115 H117 3.-.-.- O74859 SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALCNYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVS 4xba B 1.50 BS01 5GP B 1 L38 Y41 N50 R62 D63 M64 F65 K67 H71 H138 P141 S142 M143 H147 H149 L6 Y9 N18 R30 D31 M32 F33 K35 H39 H106 P109 S110 M111 H115 H117 3.-.-.- O74859 SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALCNYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVS 4xf6 A 2.08 BS01 LIP A 1 V10 D12 G25 G26 G27 Y30 Y75 R85 V112 Q136 R140 T215 G216 A217 G218 D219 V10 D12 G25 G26 G27 Y30 Y75 R85 V112 Q136 R140 T215 G216 A217 G218 D219 2.7.1.64 Q5JDA3 25972008 MKCLVVGHVVRDIVKKGNKVLERLGGGAYYSALALSRFCDVEILTSFSNLPEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELPDGEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSFLKGVKILHADLGEYQYLQGFSPEFVDVLLLSNGPEPGKAFLHGREYTFEPVHVGVDESTGAGDVFLGAFTGFYSQCPFVQALKRAAAFTALFLKNRSVDFSMDDVNELAMKVEVKRV 4xf6 A 2.08 BS02 ADP A 1 N83 H164 D166 S187 N188 G189 P190 F204 P206 V207 A217 G218 T245 L249 N83 H164 D166 S187 N188 G189 P190 F204 P206 V207 A217 G218 T245 L249 2.7.1.64 Q5JDA3 25972008 MKCLVVGHVVRDIVKKGNKVLERLGGGAYYSALALSRFCDVEILTSFSNLPEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELPDGEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSFLKGVKILHADLGEYQYLQGFSPEFVDVLLLSNGPEPGKAFLHGREYTFEPVHVGVDESTGAGDVFLGAFTGFYSQCPFVQALKRAAAFTALFLKNRSVDFSMDDVNELAMKVEVKRV 4xf6 A 2.08 BS03 INS A 1 D12 G25 G26 G27 Y30 Y75 V112 Q136 R140 T215 D219 D12 G25 G26 G27 Y30 Y75 V112 Q136 R140 T215 D219 2.7.1.64 Q5JDA3 25972008 MKCLVVGHVVRDIVKKGNKVLERLGGGAYYSALALSRFCDVEILTSFSNLPEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELPDGEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSFLKGVKILHADLGEYQYLQGFSPEFVDVLLLSNGPEPGKAFLHGREYTFEPVHVGVDESTGAGDVFLGAFTGFYSQCPFVQALKRAAAFTALFLKNRSVDFSMDDVNELAMKVEVKRV 4xf6 B 2.08 BS01 LIP B 1 D12 G25 G26 G27 Y75 R85 V112 Q136 R140 G216 G218 D219 D12 G25 G26 G27 Y75 R85 V112 Q136 R140 G216 G218 D219 2.7.1.64 Q5JDA3 25972008 MKCLVVGHVVRDIVKKGNKVLERLGGGAYYSALALSRFCDVEILTSFSNLPEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELPDGEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSFLKGVKILHADLGEYQYLQGFSPEFVDVLLLSNGPEPGKAFLHGREYTFEPVHVGVDESTGAGDVFLGAFTGFYSQCPFVQALKRAAAFTALFLKNRSVDFSMDDVNELAMKVEVKRV 4xf7 A 1.93 BS02 ACP A 1 N83 R85 H164 D166 S187 N188 G189 P190 F204 P206 V207 S214 A217 G218 T245 L249 N83 R85 H164 D166 S187 N188 G189 P190 F204 P206 V207 S214 A217 G218 T245 L249 2.7.1.64 Q5JDA3 25972008 MKCLVVGHVVRDIVKKGNKVLERLGGGAYYSALALSRFCDVEILTSFSNLPEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELPDGEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSFLKGVKILHADLGEYQYLQGFSPEFVDVLLLSNGPEPGKAFLHGREYTFEPVHVGVDESTGAGDVFLGAFTGFYSQCPFVQALKRAAAFTALFLKNRSVDFSMDDVNELAMKVEVKRV 4xf7 B 1.93 BS01 INS B 1 D12 G25 G26 G27 Y30 Y75 Q136 R140 D219 D12 G25 G26 G27 Y30 Y75 Q136 R140 D219 2.7.1.64 Q5JDA3 25972008 MKCLVVGHVVRDIVKKGNKVLERLGGGAYYSALALSRFCDVEILTSFSNLPEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELPDGEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSFLKGVKILHADLGEYQYLQGFSPEFVDVLLLSNGPEPGKAFLHGREYTFEPVHVGVDESTGAGDVFLGAFTGFYSQCPFVQALKRAAAFTALFLKNRSVDFSMDDVNELAMKVEVKRV 4xf7 B 1.93 BS02 ACP B 1 R85 H164 D166 S187 G189 P190 F204 P206 V207 V209 S214 A217 G218 F221 T245 L249 R85 H164 D166 S187 G189 P190 F204 P206 V207 V209 S214 A217 G218 F221 T245 L249 2.7.1.64 Q5JDA3 25972008 MKCLVVGHVVRDIVKKGNKVLERLGGGAYYSALALSRFCDVEILTSFSNLPEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELPDGEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSFLKGVKILHADLGEYQYLQGFSPEFVDVLLLSNGPEPGKAFLHGREYTFEPVHVGVDESTGAGDVFLGAFTGFYSQCPFVQALKRAAAFTALFLKNRSVDFSMDDVNELAMKVEVKRV 4xhe A 1.90 BS02 40P B 1 T36 Y55 I118 D164 S167 T44 Y63 I126 D172 S175 Q8WSF8 26004441 YKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe B 1.90 BS02 CA B 1 K-6 D-3 D-2 N70 K3 D6 D7 N79 Q8WSF8 26004441 DYKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe B 1.90 BS03 40P C 1 T36 Y55 R79 I118 S167 T45 Y64 R88 I127 S176 Q8WSF8 26004441 DYKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe D 1.90 BS01 40P D 1 Y93 S146 W147 V148 Y188 Y195 Y96 S149 W150 V151 Y191 Y198 Q8WSF8 26004441 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe D 1.90 BS02 40P E 1 T36 Y55 R79 I118 D164 S167 T39 Y58 R82 I121 D167 S170 Q8WSF8 26004441 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xhe E 1.90 BS01 40P A 1 T36 Y55 I118 S167 T39 Y58 I121 S170 Q8WSF8 26004441 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 4xk9 D 2.20 BS02 41J E 1 T36 Y55 R79 I118 T35 Y54 R78 I117 Q8WSF8 26004441 SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xk9 F 2.20 BS02 41J G 1 T36 Y55 R79 V108 I118 T39 Y58 R82 V111 I121 Q8WSF8 26004441 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xk9 I 2.20 BS02 41J J 1 T36 Y55 I118 T39 Y58 I121 Q8WSF8 26004441 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4xni A 2.80 BS01 78M A 1 A248 I255 A244 I251 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFALRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQG 4xni A 2.80 BS02 78M A 2 F76 V217 L220 L221 F72 V213 L216 L217 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFALRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQG 4xni A 2.80 BS03 78M A 3 A103 H176 S180 F187 A99 H172 S176 F183 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFALRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQG 4xni A 2.80 BS04 78M A 4 L444 A452 Y456 F457 L464 L414 A422 Y426 F427 L434 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFALRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQG 4xni A 2.80 BS05 78M A 5 W318 P386 W301 P369 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFALRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQG 4xni A 2.80 BS06 78M A 6 Q440 T443 L444 Q410 T413 L414 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFALRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQG 4xnj A 2.30 BS02 78M A 2 L369 I373 A376 V451 S455 L362 I366 A369 V439 S443 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 4xnj A 2.30 BS03 78M A 3 I73 F76 I81 L212 V217 V224 I69 F72 I77 L208 V213 V220 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 4xnj A 2.30 BS04 78M A 4 M96 A173 H176 S180 F187 M92 A169 H172 S176 F183 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 4xnj A 2.30 BS05 78M A 5 L370 S385 L387 W388 G391 L363 S378 L380 W381 G384 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 4xnj A 2.30 BS06 78M A 6 L444 A452 Y456 F457 L432 A440 Y444 F445 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 4xnj A 2.30 BS08 78M A 8 W318 F319 W323 F324 L327 L330 P386 L387 W311 F312 W316 F317 L320 L323 P379 L380 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 4xnj A 2.30 BS09 78M A 9 Y378 W388 Y371 W381 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 4xnj A 2.30 BS10 78M A 10 R85 P86 F89 F187 Y194 R81 P82 F85 F183 Y190 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 4xnj A 2.30 BS11 78M A 11 I59 M66 I73 L111 F112 I115 I119 L246 L253 I55 M62 I69 L107 F108 I111 I115 L242 L249 Q5M4H8 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSTSTEHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWKKNQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLNSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 4xnk A 2.80 BS01 78M A 1 W81 F88 F148 W43 F50 F95 P18895 PKNFGLDVKITGESENDRDLGTAPGGTLNDIGIDLRPWAFGQWGDWSAYFMGQAVAATDTIETDTLQSDKSYLAAREFWVDYAGLTAYPGEHLRFGRQRLREDSGQWQDTNIEALNWSFETTLLNAHAGVAQRFSEYRTDLDELAPEDKDRTHVFGDISTQWAPHHRIGVRIHHADDSGHLRRPGEEVDNLDKTYTGQLTWLGIEATGDAYNYRSSMPLNYWASATWLTGDRDNLTTTTVDDRRIATGKQSGDVNAFGVDLGLRWNIDEQWKAGVGYARGSGGGKDGEEQFQQTGLESNRSNFTGTRSRVHRFGEAFRGELSNLQAATLFGSWQLREDYDASLVYHKFWRVDDDSDIGTSGINAALQPGEKDIGQELDLVVTKYFSALIRFRGGLFKPGDAYGPGTDSTMHRAFVDFIWRF 4xnl A 2.90 BS01 78M A 1 W81 A86 Y87 F88 F131 V133 G149 W43 A48 Y49 F50 F81 V83 G99 P18895 PKNFGLDVKITGESENDRDLGTAPGGTLNDIGIDLRPWAFGQWGDWSAYFMGQAVAATDTIETDTLQSDTPDKSYLAAREFWVDYAGLTAYPGEHLRFGRQRLREDSGQWQDTNIEALNWSFETTLLNAHAGVAQRFSEYRTDLDELAPEDKDRTHVFGDISTQWAPHHRIGVRIHHADDSGHLRRPGEEVDNLDKTYTGQLTWLGIEATGDAYNYRSSMPLNYWASATWLTGDRDNLTTTTVDDRRIATGKQSGDVNAFGVDLGLRWNIDEQWKAGVGYARGSGGGKDGEEQFQQTGLESNRSNFTGTRSRVHRFGEAFRGELSNLQAATLFGSWQLREDYDASLVYHKFWRVDDDSDIGTSGINAALQPGEKDIGQELDLVVTKYFKSALIRFRGGLFKPGDAYGPGTDSTMHRAFVDFIWRF 4xnl A 2.90 BS02 78M A 2 W170 V207 G209 I225 W120 V157 G159 I175 P18895 PKNFGLDVKITGESENDRDLGTAPGGTLNDIGIDLRPWAFGQWGDWSAYFMGQAVAATDTIETDTLQSDTPDKSYLAAREFWVDYAGLTAYPGEHLRFGRQRLREDSGQWQDTNIEALNWSFETTLLNAHAGVAQRFSEYRTDLDELAPEDKDRTHVFGDISTQWAPHHRIGVRIHHADDSGHLRRPGEEVDNLDKTYTGQLTWLGIEATGDAYNYRSSMPLNYWASATWLTGDRDNLTTTTVDDRRIATGKQSGDVNAFGVDLGLRWNIDEQWKAGVGYARGSGGGKDGEEQFQQTGLESNRSNFTGTRSRVHRFGEAFRGELSNLQAATLFGSWQLREDYDASLVYHKFWRVDDDSDIGTSGINAALQPGEKDIGQELDLVVTKYFKSALIRFRGGLFKPGDAYGPGTDSTMHRAFVDFIWRF 4xnl A 2.90 BS03 78N A 1 L388 Y392 I458 F460 L338 Y342 I393 F395 P18895 PKNFGLDVKITGESENDRDLGTAPGGTLNDIGIDLRPWAFGQWGDWSAYFMGQAVAATDTIETDTLQSDTPDKSYLAAREFWVDYAGLTAYPGEHLRFGRQRLREDSGQWQDTNIEALNWSFETTLLNAHAGVAQRFSEYRTDLDELAPEDKDRTHVFGDISTQWAPHHRIGVRIHHADDSGHLRRPGEEVDNLDKTYTGQLTWLGIEATGDAYNYRSSMPLNYWASATWLTGDRDNLTTTTVDDRRIATGKQSGDVNAFGVDLGLRWNIDEQWKAGVGYARGSGGGKDGEEQFQQTGLESNRSNFTGTRSRVHRFGEAFRGELSNLQAATLFGSWQLREDYDASLVYHKFWRVDDDSDIGTSGINAALQPGEKDIGQELDLVVTKYFKSALIRFRGGLFKPGDAYGPGTDSTMHRAFVDFIWRF 4xnl A 2.90 BS04 78M A 3 L430 L432 F460 G463 L464 T478 M479 H480 L380 L382 F395 G398 L399 T413 M414 H415 P18895 PKNFGLDVKITGESENDRDLGTAPGGTLNDIGIDLRPWAFGQWGDWSAYFMGQAVAATDTIETDTLQSDTPDKSYLAAREFWVDYAGLTAYPGEHLRFGRQRLREDSGQWQDTNIEALNWSFETTLLNAHAGVAQRFSEYRTDLDELAPEDKDRTHVFGDISTQWAPHHRIGVRIHHADDSGHLRRPGEEVDNLDKTYTGQLTWLGIEATGDAYNYRSSMPLNYWASATWLTGDRDNLTTTTVDDRRIATGKQSGDVNAFGVDLGLRWNIDEQWKAGVGYARGSGGGKDGEEQFQQTGLESNRSNFTGTRSRVHRFGEAFRGELSNLQAATLFGSWQLREDYDASLVYHKFWRVDDDSDIGTSGINAALQPGEKDIGQELDLVVTKYFKSALIRFRGGLFKPGDAYGPGTDSTMHRAFVDFIWRF 4xnl A 2.90 BS05 78M A 4 W215 A216 H219 Y274 W165 A166 H169 Y224 P18895 PKNFGLDVKITGESENDRDLGTAPGGTLNDIGIDLRPWAFGQWGDWSAYFMGQAVAATDTIETDTLQSDTPDKSYLAAREFWVDYAGLTAYPGEHLRFGRQRLREDSGQWQDTNIEALNWSFETTLLNAHAGVAQRFSEYRTDLDELAPEDKDRTHVFGDISTQWAPHHRIGVRIHHADDSGHLRRPGEEVDNLDKTYTGQLTWLGIEATGDAYNYRSSMPLNYWASATWLTGDRDNLTTTTVDDRRIATGKQSGDVNAFGVDLGLRWNIDEQWKAGVGYARGSGGGKDGEEQFQQTGLESNRSNFTGTRSRVHRFGEAFRGELSNLQAATLFGSWQLREDYDASLVYHKFWRVDDDSDIGTSGINAALQPGEKDIGQELDLVVTKYFKSALIRFRGGLFKPGDAYGPGTDSTMHRAFVDFIWRF 4xs0 A 2.55 BS01 HEM A 1 Y42 F43 H45 F46 H58 K61 V62 A65 L83 L86 H87 A88 H89 V93 N97 F98 L101 L136 Y42 F43 H45 F46 H58 K61 V62 A65 L83 L86 H87 A88 H89 V93 N97 F98 L101 L136 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4xs0 B 2.55 BS01 HEM B 1 T38 F41 F42 F45 H63 K66 V67 F85 L88 H92 L96 V98 N102 F103 L106 L141 T38 F41 F42 F45 H63 K66 V67 F85 L88 H92 L96 V98 N102 F103 L106 L141 P68871 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 4xun A 1.75 BS01 CA A 1 D177 E179 S204 R206 D325 D6 E8 S33 R35 D154 3.2.1.8 O69230 26001782 ALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITAT 4xuo A 1.70 BS01 CA A 1 S15 E17 Q41 Q44 D149 S12 E14 Q38 Q41 D146 3.2.1.8 O69230 26001782 AAKAGDILLSHSFEEGTTQGWTARGGVKVDVTAEQAYQGKQSLQTTGRTEAWNGPSLSLTDVVHKNEVVEISGYVKLVAGSAPADLKFTVERRDGNGDTQYDQVNAAEQVTDQKWVKLQGQYSYEQGSSLLLYLESTDAKAAYLLDEFQIRLVKAA 4xuo B 1.70 BS01 CA B 1 S15 E17 Q41 Q44 D149 E150 S12 E14 Q38 Q41 D146 E147 3.2.1.8 O69230 26001782 AAKAGDILLSHSFEEGTTQGWTARGGVKVDVTAEQAYQGKQSLQTTGRTEAWNGPSLSLTDVVHKNEVVEISGYVKLVAGSAPADLKFTVERRDGNGDTQYDQVNAAEQVTDQKWVKLQGQYSYEQGSSLLLYLESTDAKAAYLLDEFQIRLVKAA 4xup A 2.43 BS02 CA A 2 D177 E179 S204 R206 D325 D326 D173 E175 S200 R202 D321 D322 3.2.1.8 O69230 26001782 ASAAKAGDILLSHSFEEGTTQGWTARGGVKVDVTAEQAYQGKQSLQTTGRTEAWNGPSLSLTDVVHKNEVVEISGYVKLVAGSAPADLKFTVERRDGNGDTQYDQVNAAEQVTDQKWVKLQGQYSYEQGSSLLLYLESTDAKAAYLLDEFQIRLVKAAPENPGEAGQALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITATEA 4xuq A 1.95 BS01 XYP A 1 R189 Y217 Y268 Y303 E305 W308 R18 Y46 Y97 Y132 E134 W137 3.2.1.8 O69230 26001782 ALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITAT 4xuq A 1.95 BS02 XYP A 2 R189 Y217 W308 R18 Y46 W137 3.2.1.8 O69230 26001782 ALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITAT 4xuq B 1.95 BS01 XYP B 1 R189 Y268 Y303 E305 W308 R18 Y97 Y132 E134 W137 3.2.1.8 O69230 26001782 ALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITAT 4xuq C 1.95 BS01 XYP C 1 R189 Y217 Y303 E305 R18 Y46 Y132 E134 3.2.1.8 O69230 26001782 ALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITAT 4xuq C 1.95 BS02 XYP C 2 R189 Y217 R18 Y46 3.2.1.8 O69230 26001782 ALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITAT 4xur A 1.67 BS01 XYP A 1 R189 Y217 Y268 W308 R18 Y46 Y97 W137 3.2.1.8 O69230 26001782 ALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITAT 4xur B 1.67 BS02 XYP B 2 R189 Y303 E305 W308 R18 Y132 E134 W137 3.2.1.8 O69230 26001782 ALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITAT 4xur C 1.67 BS03 XYP C 3 R189 Y303 E305 R18 Y132 E134 3.2.1.8 O69230 26001782 ALFKADFEDGNIGNWRARGTEKLEVVSGIGHNSNRSLKTSSRSETYHGPLVEVLPYLQKGSTVHISFWAMYDEGPATQVINGSLEKEFNRDTANLEYAMFASTTLNKGQWKKIEADIIVPAESTGISGLRMYAETPWKQSSEVTETDTIPFYVDDVQITAT 4xz2 A 2.67 BS01 FBP A 1 A420 R481 T538 V539 S540 M583 G584 E639 H671 Q674 A372 R433 T490 V491 S492 M535 G536 E591 H623 Q626 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEAFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4xz2 A 2.67 BS02 F6P B 1 R210 R301 R162 R253 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEAFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4xz2 B 2.67 BS02 ADP B 1 G33 G34 Y64 A96 R97 C98 F101 R102 G127 D128 G129 S130 G133 L136 G9 G10 Y40 A72 R73 C74 F77 R78 G103 D104 G105 S106 G109 L112 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEAFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4xz2 B 2.67 BS03 FBP B 1 R481 T538 V539 S540 M583 H671 Q674 R453 T510 V511 S512 M555 H643 Q646 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEAFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4xz2 B 2.67 BS04 F6P B 1 I174 D175 M217 R219 E273 H307 R310 I150 D151 M189 R191 E245 H279 R282 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEAFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4xz2 D 2.67 BS03 FBP D 1 R481 T538 S540 M583 G584 E639 H671 Q674 R452 T509 S511 M554 G555 E610 H642 Q645 2.7.1.11 Q01813 AIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKETTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4xz2 D 2.67 BS04 F6P D 1 D175 M217 R219 E273 H307 R310 D150 M188 R190 E244 H278 R281 2.7.1.11 Q01813 AIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKETTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4y16 A 2.60 BS01 48G A 1 F10 C12 Q14 S28 V30 W40 I47 W63 L66 M69 F70 Y73 S76 F77 D80 I81 L100 A102 V118 W133 L150 D153 G155 T156 T159 V160 L163 F171 F5 C7 Q9 S23 V25 W35 I42 W58 L61 M64 F65 Y68 S71 F72 D75 I76 L95 A97 V113 W128 L145 D148 G150 T151 T154 V155 L158 F166 P11609 KNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 4y9j A 1.80 BS01 FAD A 1 Q206 M208 T209 G213 G214 S215 F241 S242 S243 K295 T298 W463 T466 N468 V469 L472 Q188 M190 T191 G195 G196 S197 F223 S224 S225 K277 T280 W445 T448 N450 V451 L454 1.3.8.9 Q3T978 25981666 TITARHTQYSHAKTGGFSQTGPTLHNPYKDDPILDRTLRRLLPESEYMRVAADLSKFGDRITSEVEHLGRQAELEQPRLEHQDAWGKRVDKLIVCNEWHKLKQICAEEGVISIGYEDSVDPFVRRIHQVAKLFLFSPSAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYKWFSSAVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAIAERIGDQGRGVAGISNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLRVFSGKENILLAFGKRVEQLLGNTKTEDEKLKKSKEAVESALKQLQKLLVKASDSAIQGETRIDSVARHIAFTIARIYSGALLIDHASDSSVANQSDIEVAYRYCCEQPLIDLRWEWFASERVKADREIVFDNFT 4y9j A 1.80 BS02 UCC A 1 L159 S161 C162 A165 Q206 T209 G214 S215 A218 S267 V323 S327 L330 R334 H336 N337 A340 W463 E464 G465 D473 L141 S143 C144 A147 Q188 T191 G196 S197 A200 S249 V305 S309 L312 R316 H318 N319 A322 W445 E446 G447 D455 1.3.8.9 Q3T978 25981666 TITARHTQYSHAKTGGFSQTGPTLHNPYKDDPILDRTLRRLLPESEYMRVAADLSKFGDRITSEVEHLGRQAELEQPRLEHQDAWGKRVDKLIVCNEWHKLKQICAEEGVISIGYEDSVDPFVRRIHQVAKLFLFSPSAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYKWFSSAVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAIAERIGDQGRGVAGISNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLRVFSGKENILLAFGKRVEQLLGNTKTEDEKLKKSKEAVESALKQLQKLLVKASDSAIQGETRIDSVARHIAFTIARIYSGALLIDHASDSSVANQSDIEVAYRYCCEQPLIDLRWEWFASERVKADREIVFDNFT 4y9j A 1.80 BS03 FAD B 1 R359 V361 F362 Q366 W369 H372 E437 C438 G440 G441 Y444 R341 V343 F344 Q348 W351 H354 E419 C420 G422 G423 Y426 1.3.8.9 Q3T978 25981666 TITARHTQYSHAKTGGFSQTGPTLHNPYKDDPILDRTLRRLLPESEYMRVAADLSKFGDRITSEVEHLGRQAELEQPRLEHQDAWGKRVDKLIVCNEWHKLKQICAEEGVISIGYEDSVDPFVRRIHQVAKLFLFSPSAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYKWFSSAVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAIAERIGDQGRGVAGISNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLRVFSGKENILLAFGKRVEQLLGNTKTEDEKLKKSKEAVESALKQLQKLLVKASDSAIQGETRIDSVARHIAFTIARIYSGALLIDHASDSSVANQSDIEVAYRYCCEQPLIDLRWEWFASERVKADREIVFDNFT 4y9j B 1.80 BS03 UCC B 1 S161 C162 A165 Q206 S215 A218 S267 R321 V323 S327 L330 N331 R334 H336 N337 A340 R414 W463 E464 G465 V469 R476 S143 C144 A147 Q188 S197 A200 S249 R303 V305 S309 L312 N313 R316 H318 N319 A322 R396 W445 E446 G447 V451 R458 1.3.8.9 Q3T978 25981666 TITARHTQYSHAKTGGFSQTGPTLHNPYKDDPILDRTLRRLLPESEYMRVAADLSKFGDRITSEVEHLGRQAELEQPRLEHQDAWGKRVDKLIVCNEWHKLKQICAEEGVISIGYEDSVDPFVRRIHQVAKLFLFSPSAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYKWFSSAVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAIAERIGDQGRGVAGISNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLRVFSGKENILLAFGKRVEQLLGNTKTEDEKLKKSKEAVESALKQLQKLLVKASDSAIQGETRIDSVARHIAFTIARIYSGALLIDHASDSSVANQSDIEVAYRYCCEQPLIDLRWEWFASERVKADREIVFDNFTA 4y9l A 2.27 BS01 FAD A 1 Q206 M208 T209 G214 S215 F241 S242 S243 K295 I462 W463 E464 T466 N468 V469 L472 Q188 M190 T191 G196 S197 F223 S224 S225 K277 I444 W445 E446 T448 N450 V451 L454 1.3.8.9 Q3T978 25981666 TITARHTQYSHAKTGGFSQTGPTLHNPYKDDPILDRTLRRLLPESEYMRVAADLSKFGDRITSEVEHLGRQAELEQPRLEHQDAWGKRVDKLIVCNEWHKLKQICAEEGVISIGYEDSVDPFVRRIHQVAKLFLFSPSAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYKWFSSAVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAIAERIGDQGRGVAGISNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLRVFSGKENILLAFGKRVEQLLGNTKTEDEKLKKSKEAVESALKQLQKLLVKASDSAIQGETRIDSVARHIAFTIARIYSGALLIDHASDSSVANQSDIEVAYRYCCEQPLIDLRWEWFASERVKADREIVFDNFT 4y9l B 2.27 BS02 FAD B 1 Q206 M208 T209 G214 S215 F241 S242 S243 K295 V459 W463 T466 N468 V469 L472 Q188 M190 T191 G196 S197 F223 S224 S225 K277 V441 W445 T448 N450 V451 L454 1.3.8.9 Q3T978 25981666 TITARHTQYSHAKTGGFSQTGPTLHNPYKDDPILDRTLRRLLPESEYMRVAADLSKFGDRITSEVEHLGRQAELEQPRLEHQDAWGKRVDKLIVCNEWHKLKQICAEEGVISIGYEDSVDPFVRRIHQVAKLFLFSPSAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYKWFSSAVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAIAERIGDQGRGVAGISNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLRVFSGKENILLAFGKRVEQLLGNTKTEDEKLKKSKEAVESALKQLQKLLVKASDSAIQGETRIDSVARHIAFTIARIYSGALLIDHASDSSVANQSDIEVAYRYCCEQPLIDLRWEWFASERVKADREIVFDNFTA 4ydj H 2.31 BS01 BU3 H 1 G190 T193 K210 G212 T215 K232 QVQLVQPGTAMKSLGSSLTITCRVSGDDLGSFHFGTYFMIWVRQAPGQGLEYMGGILPSTKTPTYAHKFRGRVSISAPGVPPVLSLALTNLTYDDTATYFCARERGRHFEPKNRDNLEGKFFDLWGRGTFVRVSPASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 4ydj B 2.31 BS01 BU3 A 1 Y87 A100 G101 Y83 A93 G94 QSALTQPASVSGSPGQSINISCAGRSDRVSWYQQRPNGVPKLLMFDVYRRPSGVSDRFSGSHSGDTAFLTISGLQTEDEADYYCTSHPYAFGAGTKVNVLRQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPTEC 4ydj B 2.31 BS02 BU3 B 1 K149 D151 S152 S192 E203 K143 D145 S146 S186 E197 QSALTQPASVSGSPGQSINISCAGRSDRVSWYQQRPNGVPKLLMFDVYRRPSGVSDRFSGSHSGDTAFLTISGLQTEDEADYYCTSHPYAFGAGTKVNVLRQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPTEC 4ydj B 2.31 BS03 BU3 B 2 Q194 T201 E203 Q188 T195 E197 QSALTQPASVSGSPGQSINISCAGRSDRVSWYQQRPNGVPKLLMFDVYRRPSGVSDRFSGSHSGDTAFLTISGLQTEDEADYYCTSHPYAFGAGTKVNVLRQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPTEC 4yke A 2.78 BS01 MN A 1 D17 H19 D57 H243 D14 H16 D54 H237 G0RYR3 TAGPDTIRILVSTDNHVGYEERDPIRKDDSWRTFDEIMQLARTKDVDMVLLGGDLFHDNKPSRKAMYQVMRSLRKNCLGMKPCELEFLSDPAEVFEGAFPHVNYYDPDINVSIPVFSIHGNHDDPSGDGHLCSLDLLQVAGLVNYFGRVPEADNIHVKPILLQKGKTKLALYGMSNVRDERIHRTFRDNKVRFYRPTGDWFNLLTLHQNHYAHTPTGYLSENMLPDFLDLVIWGHEHECLIDPKKNPETGFHVMQPGSSIATSLVPGEAVPKHIAILSITGKSFEVEKIPLRTVRPFVIREITLATDKRFKGLEKKQDNRQEVTKRLMQIVEEMIAEANEMWRSLHEDSQDDEEQPLPLIRLKVEYSSPEGTKFEVENPQRFSNRFAGKVANQNDVVHFYRKKT 4yke A 2.78 BS02 MN A 2 D17 D57 N124 H213 H241 D14 D54 N121 H207 H235 G0RYR3 TAGPDTIRILVSTDNHVGYEERDPIRKDDSWRTFDEIMQLARTKDVDMVLLGGDLFHDNKPSRKAMYQVMRSLRKNCLGMKPCELEFLSDPAEVFEGAFPHVNYYDPDINVSIPVFSIHGNHDDPSGDGHLCSLDLLQVAGLVNYFGRVPEADNIHVKPILLQKGKTKLALYGMSNVRDERIHRTFRDNKVRFYRPTGDWFNLLTLHQNHYAHTPTGYLSENMLPDFLDLVIWGHEHECLIDPKKNPETGFHVMQPGSSIATSLVPGEAVPKHIAILSITGKSFEVEKIPLRTVRPFVIREITLATDKRFKGLEKKQDNRQEVTKRLMQIVEEMIAEANEMWRSLHEDSQDDEEQPLPLIRLKVEYSSPEGTKFEVENPQRFSNRFAGKVANQNDVVHFYRKKT 4ykl B 2.25 BS01 NUC A 1 F34 F65 K67 S142 K161 H165 F2 F33 K35 S110 K129 H133 3.-.-.- O74859 SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALCNYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSV 4ykl B 2.25 BS03 GMP B 1 L38 Y41 R62 D63 M64 F65 K67 M143 H147 L6 Y9 R30 D31 M32 F33 K35 M111 H115 3.-.-.- O74859 SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALCNYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSV 4yl6 A 2.10 BS01 III B 1 L299 M303 L306 R307 S312 I315 Q316 F318 A319 L322 H323 Y325 R326 P355 F356 P358 L9 M13 L16 R17 S22 I25 Q26 F28 A29 L32 H33 Y35 R36 P65 F66 P68 Q9BSQ5 25982527 LSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDLE 4ymj A 2.00 BS01 4EJ A 1 L544 G545 V552 A570 K572 F617 E618 Y619 M620 G623 L686 F698 L18 G19 V26 A44 K46 F91 E92 Y93 M94 G97 L146 F158 2.7.10.1 Q16288 26005534 GIHVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGDVYSTDYYRHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKAT 4yne A 2.02 BS01 4EK A 1 F521 V524 A542 F589 E590 M592 R654 N655 L657 G667 D668 F25 V28 A44 F86 E87 M89 R151 N152 L154 G164 D165 2.7.10.1 P04629 26005534 GSGIRVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPDKMLVAVKALKERQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSTDYYRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLD 4yps A 2.10 BS01 4F6 A 1 L516 G517 V524 A542 V573 F589 E590 Y591 M592 G595 D596 R654 N655 L657 L20 G21 V25 A40 V68 F84 E85 Y86 M87 G90 D91 R149 N150 L152 2.7.10.1 P04629 26005534 GSGIRVHHIKRRDIVLKWELGEGKVFLAECHNLLDKMLVAVKALSESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDMSRDIYSTDYYRVTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPV 4ys0 A 1.90 BS01 ADP A 1 M74 R75 P76 F77 Q80 G98 E99 G100 K101 T102 L103 W135 D537 K539 M73 R74 P75 F76 Q79 G97 E98 G99 K100 T101 L102 W134 D536 K538 Q9X1R4 25982945 ILFDKNKRILKKYAKMVSKINQIESDLRSKKNSELIRLSMVLKEKVNSFEDADEHLFEAFALVREAARRTLGMRPFDVQVMGGIALHEGKVAEMKTGEGKTLAATMPIYLNALIGKGVHLVTVNDYLARRDALWMGPVYLFLGLRVGVINSLGKSYEVVWKNPDLARKAIEENWSVWPDGFNGEVLKEESMNKEAVEAFQVELKEITRKEAYLCDVTYGTNNEFGFDYLRDNLVLDYNDKVQRGHFYAIVDEADSVLIDEARTPLIISGPSKESPSVYRRFAQIAKKFVKDKDFTVDEKARTIILTEEGVAKAEKIIGVENLYDPGNVSLLYHLINALKALHLFKKDVDYVVMNGEVIIVDEFTGRLLPGRRYSGGLHQAIEAKEGVPIKEESITYATITFQNYFRMYEKLAGMTGTAKTEESEFVQVYGMEVVVIPTHKPMIRKDHDDLVFRTQKEKYEKIVEEIEKRYKKGQPVLVGTTSIEKSELLSSMLKKKGIPHQVLNAKYHEKEAEIVAKAGQKGMVTIATNMAGRGTDIKLGPGVAELGGLCIIGTERHESRRIDNQLRGRAGRQGDPGESIFFLSLEDDLLRIFGSEQIGKVMNILKIEEGQPIQHPMLSKLIENIQKKVEGINFSIRKTLMEMDDVLDKQRRAVYSLRDQILLEKDYDEYLKDIFEDVVSTRVEEFCSGKNWDIESLKNSLSFFPAGLFDLDEKQFSSSEELHDYLFNRLWEEYQRKKQEIGEDYRKVIRFLMLRIIDDHWRRYLEEVEHVKEAVQLRSDPIVEFKKETYYMFDEMMRRINDTIANYVLRVLEH 4yvz A 2.50 BS01 MN A 1 E229 D232 D233 E223 D226 D227 2.7.7.85 Q9WY43 VPQELIEKIKLISPGTELRKALDDIINANFGALIFLVDDPKKYEDVIQGGFWLDTDFSAEKLYELSKMDGAIVLSEDITKIYYANVHLVPDPTIPTGETGTRHRTAERLAKQTGKVVIAVSRRRNIISLYYKNYKYVVNQVDFLISKVTQAISTLEKYKDNFNKLLSELEVLELENRVTLADVVRTLAKGFELLRIVEEIRPYIVELGEEGRLARMQLRELTEDVDDLLVLLIMDYSSEEVEEETAQNILQDFITRREPSPISISRVLGYDVQQAAQLDDVLVSARGYRLLKTVARIPLSIGYNVVRMFKTLDQISKASVEDLKKVEGIGEKRARAISESISSLKHRKT 4yvz A 2.50 BS02 3AT B 1 L39 D75 G76 V92 H93 L94 G106 T107 R108 H109 T111 S127 R128 R130 L33 D69 G70 V86 H87 L88 G100 T101 R102 H103 T105 S121 R122 R124 2.7.7.85 Q9WY43 VPQELIEKIKLISPGTELRKALDDIINANFGALIFLVDDPKKYEDVIQGGFWLDTDFSAEKLYELSKMDGAIVLSEDITKIYYANVHLVPDPTIPTGETGTRHRTAERLAKQTGKVVIAVSRRRNIISLYYKNYKYVVNQVDFLISKVTQAISTLEKYKDNFNKLLSELEVLELENRVTLADVVRTLAKGFELLRIVEEIRPYIVELGEEGRLARMQLRELTEDVDDLLVLLIMDYSSEEVEEETAQNILQDFITRREPSPISISRVLGYDVQQAAQLDDVLVSARGYRLLKTVARIPLSIGYNVVRMFKTLDQISKASVEDLKKVEGIGEKRARAISESISSLKHRKT 4yxb A 2.56 BS01 III C 1 Y66 G67 T68 V69 Y73 A74 R76 V176 Y208 Y49 G50 T51 V52 Y56 A57 R59 V110 Y142 P26419 25994170 ELELVANFADIPLRLSQILKLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTVNGQYALRVEHLINPILNSLNEAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR 4yxj A 2.55 BS01 APC A 1 L39 G76 V92 H93 L94 G106 T107 R108 T111 S127 R128 R129 L33 G70 V86 H87 L88 G100 T101 R102 T105 S121 R122 R123 2.7.7.85 Q9WY43 VPQELIEKIKLISPGTELRKALDDIINANFGALIFLVDDPKKYEDVIQGGFWLDTDFSAEKLYELSKMDGAIVLSEDITKIYYANVHLVPDPTIPTGETGTRHRTAERLAKQTGKVVIAVSRRRNIISLYYKNYKYVVNQVDFLISKVTQAISTLEKYKDNFNKLLSELEVLELENRVTLADVVRTLAKGFELLRIVEEIRPYIVELGEEGRLARMQLRELTEDVDDLLVLLIMDYSSEEVEEETAQNILQDFITRREPSPISISRVLGYDVQQAAQLDDVLVSARGYRLLKTVARIPLSIGYNVVRMFKTLDQISKASVEDLKKVEGIGEKRARAISESISSLKHRKT 4yxj B 2.55 BS01 APC B 1 L39 G76 A77 V92 H93 L94 G106 T107 R108 T111 S127 R128 R129 R130 L33 G70 A71 V86 H87 L88 G100 T101 R102 T105 S121 R122 R123 R124 2.7.7.85 Q9WY43 VPQELIEKIKLISPGTELRKALDDIINANFGALIFLVDDPKKYEDVIQGGFWLDTDFSAEKLYELSKMDGAIVLSEDITKIYYANVHLVPDPTIPTGETGTRHRTAERLAKQTGKVVIAVSRRRNIISLYYKNYKYVVNQVDFLISKVTQAISTLEKYKDNFNKLLSELEVLELENRVTLADVVRTLAKGFELLRIVEEIRPYIVELGEEGRLARMQLRELTEDVDDLLVLLIMDYSSEEVEEETAQNILQDFITRREPSPISISRVLGYDVQQAAQLDDVLVSARGYRLLKTVARIPLSIGYNVVRMFKTLDQISKASVEDLKKVEGIGEKRARAISESISSLKHRKT 4yxm A 2.25 BS01 2BA B 1 L39 N75 G76 V92 H93 L94 T107 R108 T111 L33 N69 G70 V86 H87 L88 T101 R102 T105 2.7.7.85 Q9WY43 VPQELIEKIKLISPGTELRKALDDIINANFGALIFLVDDPKKYEDVIQGGFWLDTDFSAEKLYELSKMNGAIVLSEDITKIYYANVHLVPDPTIPTGETGTRHRTAERLAKQTGKVVIAVSRRRNIISLYYKNYKYVVNQVDFLISKVTQAISTLEKYKDNFNKLLSELEVLELENRVTLADVVRTLAKGFELLRIVEEIRPYIVELGEEGRLARMQLRELTEDVDDLLVLLIMDYSSEEVEEETAQNILQDFITRREPSPISISRVLGYDVQQAAQLDDVLVSARGYRLLKTVARIPLSIGYNVVRMFKTLDQISKASVEDLKKVEGIGEKRARAISESISSLKHRKT 4yxm B 2.25 BS01 2BA B 1 L39 N75 G76 V92 H93 L94 T107 R108 T111 R128 L33 N69 G70 V86 H87 L88 T101 R102 T105 R122 2.7.7.85 Q9WY43 VPQELIEKIKLISPGTELRKALDDIINANFGALIFLVDDPKKYEDVIQGGFWLDTDFSAEKLYELSKMNGAIVLSEDITKIYYANVHLVPDPTIPTGETGTRHRTAERLAKQTGKVVIAVSRRRNIISLYYKNYKYVVNQVDFLISKVTQAISTLEKYKDNFNKLLSELEVLELENRVTLADVVRTLAKGFELLRIVEEIRPYIVELGEEGRLARMQLRELTEDVDDLLVLLIMDYSSEEVEEETAQNILQDFITRREPSPISISRVLGYDVQQAAQLDDVLVSARGYRLLKTVARIPLSIGYNVVRMFKTLDQISKASVEDLKKVEGIGEKRARAISESISSLKHRKT 4z25 A 3.34 BS01 FAD A 1 G13 G15 A16 A17 E37 A38 S68 W75 A93 H94 G95 M96 G100 S101 I104 N105 R106 L107 N108 A261 V263 T297 S298 G299 S577 H578 D605 L606 N616 T617 W618 A621 G10 G12 A13 A14 E34 A35 S65 W72 A90 H91 G92 M93 G97 S98 I101 N102 R103 L104 N105 A258 V260 T294 S295 G296 S574 H575 D602 L603 N613 T614 W615 A618 1.-.-.- Q5UPL2 NLTGDIVIIGAGAAGSLLAHYLARFSNMKIILLEAGHSHFNDPVVTDPMGFFGKYNPPNENISMSQNPSYSWQGAQEPNTGAYGNRPIIAHGMGFGGSTMINRLNLVVGGRTVFDNDWPVGWKYDDVKNYFRRVLVDINPVRDNTKASITSVALDALRIIAEQQIASGEPVDFLLNKATGNVPNVEKTTPDAVPLNLNDYEGVNSVVAFSSFYMGVNQLSDGNYIRKYAGNTYLNRNYVDENGRGIGKFSGLRVVSDAVVDRIIFKGNRAVGVNYIDREGIMHYVKVNKEVVVTSGAFYTPTILQRSGIGDFTYLSSIGVKNLVYNNPLVGTGLKNHYSPVTITRVHGEPSEVSRFLSNMAANPTNMGFKGLAELGFHRLDPNKPANANTVTYRKYQLMMTAGVGIPAEQQYLSGLSPSSNNLFTLIADDIRFAPEGYIKIGTPNIPRDVPKIFFNTFVTYTPTSAPADQQWPIAQKTLAPLISALLGYDIIYQTLMSMNQTARDSGFQVSLEMVYPLNDLIYKLHNGLATYGANWWHYFVPTLVGDDTPAGREFADTLSKLSYYPRVGAHLDSHQGCSCSIGRTVDSNLKVIGTQNVRVADLSAAAFPPGGNTWATASMIGARAVDLILGFPYLRDLPVNDVPILNVN 4z25 E 3.34 BS01 FAD E 1 G13 G15 A16 A17 E37 A38 S68 W75 A93 H94 G95 M96 G97 G100 S101 I104 N105 R106 L107 N108 A261 V263 S298 S577 H578 D605 L606 N616 T617 W618 G10 G12 A13 A14 E34 A35 S65 W72 A90 H91 G92 M93 G94 G97 S98 I101 N102 R103 L104 N105 A258 V260 S295 S574 H575 D602 L603 N613 T614 W615 1.-.-.- Q5UPL2 NLTGDIVIIGAGAAGSLLAHYLARFSNMKIILLEAGHSHFNDPVVTDPMGFFGKYNPPNENISMSQNPSYSWQGAQEPNTGAYGNRPIIAHGMGFGGSTMINRLNLVVGGRTVFDNDWPVGWKYDDVKNYFRRVLVDINPVRDNTKASITSVALDALRIIAEQQIASGEPVDFLLNKATGNVPNVEKTTPDAVPLNLNDYEGVNSVVAFSSFYMGVNQLSDGNYIRKYAGNTYLNRNYVDENGRGIGKFSGLRVVSDAVVDRIIFKGNRAVGVNYIDREGIMHYVKVNKEVVVTSGAFYTPTILQRSGIGDFTYLSSIGVKNLVYNNPLVGTGLKNHYSPVTITRVHGEPSEVSRFLSNMAANPTNMGFKGLAELGFHRLDPNKPANANTVTYRKYQLMMTAGVGIPAEQQYLSGLSPSSNNLFTLIADDIRFAPEGYIKIGTPNIPRDVPKIFFNTFVTYTPTSAPADQQWPIAQKTLAPLISALLGYDIIYQTLMSMNQTARDSGFQVSLEMVYPLNDLIYKLHNGLATYGANWWHYFVPTLVGDDTPAGREFADTLSKLSYYPRVGAHLDSHQGCSCSIGRTVDSNLKVIGTQNVRVADLSAAAFPPGGNTWATASMIGARAVDLILGFPYLRDLPVNDVPILNVN 4z34 A 3.00 BS01 ON7 A 1 K39 H40 V52 T109 T113 Q125 I128 D129 L132 M198 L207 W271 G274 L277 L278 E293 K294 F296 L297 K20 H21 V33 T90 T94 Q106 I109 D110 L113 M179 L188 W329 G332 L335 L336 E351 K352 F354 L355 Q92633 NEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKAMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG 4z34 A 3.00 BS02 1WV A 1 L122 L123 T130 G179 L103 L104 T111 G160 Q92633 NEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKAMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG 4z35 A 2.90 BS01 ON9 A 1 Y34 K39 T113 R124 Q125 I128 D129 L132 M198 L207 W210 W271 G274 L277 L278 E293 K294 F296 L297 Y12 K17 T91 R102 Q103 I106 D107 L110 M176 L185 W188 W326 G329 L332 L333 E348 K349 F351 L352 Q92633 QCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKAMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG 4z35 A 2.90 BS02 1WV A 1 T130 G179 S183 T108 G157 S161 Q92633 QCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKAMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG 4z36 A 2.90 BS01 ON3 A 1 V52 M106 T109 Q125 I128 D129 L132 M198 L207 W210 W271 G274 L278 E293 K294 F296 L297 V30 M84 T87 Q103 I106 D107 L110 M176 L185 W188 W326 G329 L333 E348 K349 F351 L352 Q92633 QCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSCSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKGMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDCCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG 4z36 A 2.90 BS02 1WV A 1 F97 L122 L123 T130 G179 S183 F75 L100 L101 T108 G157 S161 Q92633 QCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSCSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKGMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDCCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG 4z7u A 2.70 BS01 III J 1 Y9 Y22 H24 W43 F51 R52 R53 F54 N62 V65 L66 H68 N69 I72 V73 R76 Y10 Y24 H26 W45 F53 R54 R55 F56 N64 V67 L68 H70 N71 I74 V75 R78 Q30069 25948817 DIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPLLKHWEP 4z7u B 2.70 BS02 FUC B 1 N19 G20 T21 N18 G19 T20 O19707 25948817 DSPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTISPLLVCSVTDFYPAQIKVRWQEETTGVVSTPLIRNGDWTFQILVMLEMDVYTCHVEHPSLQNPIIVEWR 4z7u C 2.70 BS01 III I 1 Y8 Y22 H24 W43 F51 R52 R53 F54 N62 H68 N69 V73 R76 Y10 Y24 H26 W45 F53 R54 R55 F56 N64 H70 N71 V75 R78 Q30069 25948817 DIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPLLKHWEP 4z7u D 2.70 BS02 FUC D 1 N19 T21 N18 T20 O19707 25948817 DSPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTISPSLLVCSVTDFYPAQIKVRWQEETTGVVSTPLIRNGDWTFQILVMLEMRGDVYTCHVEHPSLQNPIIVEWR 4z7u E 2.70 BS01 III I 1 T36 R109 T30 R93 25948817 DAKTTQPNSMESNEEEPVHLPCNHSTISGTDYIHWYRQLPSQGPEYVIHGLTSNVNNRMASLAIAEDRKSSTLILHRATLRDAAVYYCILRDRSNQFYFGTGTSLTVIPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP 4z7u F 2.70 BS01 III I 1 Y57 T108 T109 G111 T112A Y50 T95 T96 G98 T99 25948817 DSGVTQTPKHLITATGQRVTLRCSPRSGDLSVYWYQQSLDQGLQFLIQYYNGEERAKGNILERFSAQQFPDLHSELNLSSLELGDSALYFCASSTTPGTGTETQYFGPGTRLLVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 4z7u H 2.70 BS01 III J 1 L37 Y57 T108 T109 G111 T112A L30 Y50 T95 T96 G98 T99 25948817 DSGVTQTPKHLITATGQRVTLRCSPRSGDLSVYWYQQSLDQGLQFLIQYYNGEERAKGNILERFSAQQFPDLHSELNLSSLELGDSALYFCASSTTPGTGTETQYFGPGTRLLVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 4z7v D 2.65 BS02 FUC D 1 N19 G20 T21 E22 N18 G19 T20 E21 O19707 25948817 DSPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTISPSLLVCSVTDFYPAQIKVRWFQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEW 4z7v E 2.65 BS01 III I 1 T36 S109 R110 T30 S93 R94 25948817 DAKTTQPNSMESNEEEPVHLPCNHSTISGTDYIHWYRQLPSQGPEYVIHGLTSNVNNRMASLAIAEDRKSSTLILHRATLRDAAVYYCILRDSRAQKLVFGQGTRLTINPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP 4z7v F 2.65 BS01 III I 1 L37 Y57 A108 G109 S111 G112 L30 Y50 A95 G96 S98 G99 25948817 DSGVTQTPKHLITATGQRVTLRCSPRSGDLSVYWYQQSLDQGLQFLIQYYNGEERAKGNILERFSAQQFPDLHSELNLSSLELGDSALYFCASSAGTSGEYEQYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 4z7v G 2.65 BS01 III J 1 S109 R110 S92 R93 25948817 AKTTQPNSMESNEEEPVHLPCNHSTISGTDYIHWYRQLPSQGPEYVIHGLTSNVNNRMASLAIAEDRKSSTLILHRATLRDAAVYYCILRDSRAQKLVFGQGTRLTINPNIQNPDPAVYQLRDSKSKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSP 4z7w A 2.89 BS01 III J 1 Y9 Y22 H24 W43 R52 R53 F54 N62 V65 H68 N69 I72 V73 R76 Y9 Y23 H25 W44 R53 R54 F55 N63 V66 H69 N70 I73 V74 R77 Q30069 25948817 IVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFLPSADEIYDCKVEHWGLDEPLLKHWEP 4z7w F 2.89 BS01 III I 1 N28 N37 K84 E108 A109 R110 N114 N26 N28 K69 E93 A94 R95 N98 25948817 GVTQTPKFQVLKTGQSMTLQCAQDMNHNSMYWYRQDPGMGLRLIYYSASEGTTDKGEVPNGYNVSRLNKREFSLRLESAAPSQTSVYFCASSEARRYNEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 4z7w H 2.89 BS01 III J 1 N28 N37 E108 A109 R110 N114 N26 N28 E93 A94 R95 N98 25948817 GVTQTPKFQVLKTGQSMTLQCAQDMNHNSMYWYRQDPGMGLRLIYYSASEGTTDKGEVPNGYNVSRLNKREFSLRLESAAPSQTSVYFCASSEARRYNEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 4zae A 1.86 BS01 4M1 A 1 Y99 R143 H147 K148 F174 D189 S190 C191 Q192 S195 I213 S214 W215 G216 E217 C220 G226 Y86 R132 H135 K136 F162 D179 S180 C181 Q182 S185 I203 S204 W205 G206 E207 C209 G216 3.4.21.22 P00740 25978966 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGASALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKL 4zbk B 2.18 BS01 4M8 B 1 T381 N401 E420 D423 S451 S452 A472 G473 G474 I477 T1 N21 E40 D43 S71 S72 A92 G93 G94 I97 2.3.2.2,3.4.19.13,3.4.19.14 P19440 TAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY 4zc6 B 2.10 BS01 SEE B 1 T381 T399 N401 E420 D423 S451 S452 G473 G474 T1 T19 N21 E40 D43 S71 S72 G93 G94 2.3.2.2,3.4.19.13,3.4.19.14 P19440 TAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY 4zcg B 2.22 BS01 GLU B 1 T381 N401 E420 D423 S451 S452 G473 G474 T1 N21 E40 D43 S71 S72 G93 G94 2.3.2.2,3.4.19.13,3.4.19.14 P19440 TAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY 4zim A 2.65 BS01 4OK A 1 Q853 L855 G856 K857 V863 A880 E930 Y931 L932 G935 L983 D994 Q12 L14 G15 K16 V22 A39 E86 Y87 L88 G91 L139 D150 2.7.10.2 O60674 25987372 TQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMA 4zim B 2.65 BS01 4OK B 1 Q853 Q854 L855 G856 K857 V863 A880 K882 E930 Y931 L932 P933 G935 L983 D994 Q17 Q18 L19 G20 K21 V27 A44 K46 E94 Y95 L96 P97 G99 L147 D158 2.7.10.2 O60674 25987372 HMRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG 4zj7 A 2.40 BS01 III B 1 D353 E396 C429 N430 Q434 H470 A473 A474 V476 N477 Q512 D335 E378 C411 N412 Q416 H452 A455 A456 V458 N459 Q494 P32337 ALPEEVNRTLLQIVQAFQIRSVAEKALSEEWITENNIEYLLTFLAEQAAFSQDTTVAALSAVLFRKLALKAPITHIRKEVLAQIRSSLLKGFLSERADSIRHKLSDAIAECVQDDLPAWPELLQALIESLKSGNPNFRESSFRILTTVPYLITAVDINSILPIFQSGFTDASDNVKIAAVTAFVGYFKQLPKSEWSKLGILLPSLLNSLPRFLDDGKDDALASVFESLIELVELAPKLFKDMFDQIIQFTDMVIKNKDLEPPARTTALELLTVFSENAPQMCKSNQNYGQTLVMVTLIMMTEVSIDDDDAAEWIESDDTDDEEEVTYDHARQALDRVALKLGGEYLAAPLFQYLQQMITSTEWRERFAAMMALSSAAEGCADVLIGEIPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFSPFIQRTAHDRILPALISKLTSECTSRVQTHAAAALVNFSEFASKDILEPYLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEAAKNKFIKYYDTLMPLLLNVLKVNSVLKGKCMECATLIGFAVGKEKFHEHSQELISILVALQNSDALRSYLEQSWSRICRILGDDFVPLLPIVIPPLLITAKATQDVGLIEEEEAANFQQYPDWDVVQVQGKHIAIHTSVLDDKVSAMELLQSYATLLRGQFAVYVKEVMEEIALPSLDFYLHDGVRAAGATLIPILLSCLLAATNEELVLLWHKASSKLIGGLMSEPMPEITQVYHNSLVNGIKVMGDNCLSEDQLAAFTKGVSANLTDTYERMQDDEYNENEEDFTDEDLLDEINKSIAAVLKTTNGHYLKNLENIWPMINTFLLDNEPILVIFALVVIGDLIQYNAFIPKVTECLISPDARIRQAASYIIGVCAQYAADVCIPTLDTLVQIVDSKLEENRSSTENASAAIAKILYAYNVDTYTANWFKTLPTITDKEAASFNYQFLSQLIEQSNISAVVDSVIQALNERSLTTVISSVKKLLGFLPSSDAMAIFNRYPADIMEKVHKWFA 4zv3 A 3.10 BS01 COA A 1 A107 L108 A109 R110 S136 K137 H138 S139 W165 V167 L169 Y198 Q201 K202 R205 V249 H250 G251 T254 N283 F284 H285 D286 K287 A50 L51 A52 R53 S79 K80 H81 S82 W108 V110 L112 Y141 Q144 K145 R148 V177 H178 G179 T182 N211 F212 H213 D214 K215 3.1.2.2 Q91V12 VTMGRIMRPDDANVAGNVHGGTILKMIEEAGAIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSVEVQVHVMSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQEEEGRKRYEAQKLERMPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDNSQKRYRAASAFFTYVSLNQEGKPMPVPQLVPETEDEKKRFEEGKGRYLQ 4zv3 B 3.10 BS01 COA B 1 A107 L108 A109 R110 S136 K137 H138 S139 W165 L169 Y198 K202 R205 T254 N283 F284 H285 D286 K287 A50 L51 A52 R53 S79 K80 H81 S82 W108 L112 Y141 K145 R148 T183 N212 F213 H214 D215 K216 3.1.2.2 Q91V12 VTMGRIMRPDDANVAGNVHGGTILKMIEEAGAIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSVEVQVHVMSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQEEEGRKRYEAQKLERMEPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDNSQKRYRAASAFFTYVSLNQEGKPMPVPQLVPETEDEKKRFEEGKGRYLQ 4zv3 C 3.10 BS01 COA C 1 A107 L108 A109 R110 S136 K137 H138 S139 V167 L169 V177 Y198 Q201 K202 R205 T254 N283 F284 H285 D286 K287 A50 L51 A52 R53 S79 K80 H81 S82 V110 L112 V120 Y141 Q144 K145 R148 T183 N212 F213 H214 D215 K216 3.1.2.2 Q91V12 VTMGRIMRPDDANVAGNVHGGTILKMIEEAGAIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSVEVQVHVMSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQEEEGRKRYEAQKLERMEPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDNSQKRYRAASAFFTYVSLNQEGKPMPVPQLVPETEDEKKRFEEGKGRYLQ 4zwm B 2.31 BS01 PLP B 1 T135 G136 A137 Y171 W172 E224 D257 I259 Q260 K286 T118 G119 A120 Y154 W155 E207 D240 I242 Q243 K269 2.6.1.13 S8EY38 ARKTNIEAYRDGLKLKTEEDFFACDRQYVCQNYAVPVVISKGKGARVWDINGNEYYDFLAGVSSLSQGHCHPRVIAALCRQAERLTLTLRAFGNDVTGPACRFMAEMFGYDRVLLMNTGAEAGESALKIARKWAYEVKEIPPDSAKVILCNNNYWGRTITACSSSTTFDCYNNFGPFTPGFELIDYDDVGALEEALKDPNVAAFFVEPIQGEGGVNVPKPGYLKRAHELCRSKNVLLIVDEIQTGLCRTGRLLAADHDEVHPDILLLGKSLSAGVVPISAVMGRADVMDVLKPGTHGSTFGGNPLACAVAVEALTVLKDEKLADRAERLGAQFRDCLRRELYGKVPWIKEIRGRGLLNAVEVDSDAIDPNDVVMKLKENGILSKPTRGRVMRFIPPLVITDEEHRDATTRIIKSFLAVEEERK 5a2i H 1.88 BS01 III P 1 N31 Y32 W33 Q97 Y1032 W1091 W1096 N31 Y32 W33 Q103 Y148 W207 W212 P01727 QVQLQESGGGLVQPGGSMKLSCVASGFTFSNYWMNWVRQSPEKGLEWVAEIRLKSNNYATHYAESVKGRFTISRDDSKSSVYLQMNNLRAEDTGIYYCTGVGQFAYWGQGTTVTVSVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGVPARFSGSLIGDKAALTITGAQTEDEAIYFCALWYSNHWVFGGGTKLTVLG 5a2l H 1.79 BS01 III P 1 N31 Y32 W33 L52A V95 Q97 Y1032 W1091 W1096 N30 Y31 W32 L52 V100 Q102 Y149 W208 W213 P01727 VQLQESGGGLVQPGGSMKLSCVASGFTFSNYWMNWVRQSPEKGLEWVAEIRLKSNNYATHYAESVKGRFTISRDDSKSSVYLQMNNLRAEDTGIYYCTGVGQFAYWGQGTTVTVSDIVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGVPARFSGSLIGDKAALTITGAQTEDEAIYFCALWYSNHWVFGGGTKLTVLG 5af7 A 1.89 BS01 FAD A 1 I121 I123 S124 G129 S130 W154 T156 E210 M361 A365 G366 T368 Q370 I371 Q387 I119 I121 S122 G127 S128 W152 T154 E208 M359 A363 G364 T366 Q368 I369 Q385 3.13.1.4 K4L7X3 ELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDKPAICISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARLMLRSAAVSGETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRTQVASKILDMKLPQTRDGY 5af7 A 1.89 BS02 FAD B 1 R272 Q274 F275 L279 F282 L285 Q339 F340 G342 S343 Y346 R270 Q272 F273 L277 F280 L283 Q337 F338 G340 S341 Y344 3.13.1.4 K4L7X3 ELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDKPAICISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARLMLRSAAVSGETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRTQVASKILDMKLPQTRDGY 5agu A 2.17 BS01 III C 1 R183 F184 M396 P397 V398 R399 R166 F167 M368 P369 V370 R371 2.7.7.7 I6XU56 DLTFRLLRESFADAVSWVAKNLPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVAAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGNGNGPFPAVSTDYVYLLMPVRLP 5agu A 2.17 BS02 VAL C 1 K260 Q263 K243 Q246 2.7.7.7 I6XU56 DLTFRLLRESFADAVSWVAKNLPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVAAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGNGNGPFPAVSTDYVYLLMPVRLP 5agu A 2.17 BS03 BU3 A 1 E135 S194 A195 S196 E118 S177 A178 S179 2.7.7.7 I6XU56 DLTFRLLRESFADAVSWVAKNLPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVAAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGNGNGPFPAVSTDYVYLLMPVRLP 5agu B 2.17 BS02 PRO D 1 L264 K361 P362 L249 K346 P347 2.7.7.7 I6XU56 DLTFRLLRESFADAVSWVAKNLPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDGNGPFPAVSTDYVYLLMPVRLP 5agv A 1.93 BS01 III C 1 M163 R183 F184 R185 L186 E257 K260 Q263 L264 M396 P397 V398 R399 M154 R174 F175 R176 L177 E248 K251 Q254 L255 M384 P385 V386 R387 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPLNGNGPFPAVSTDYVYLLMPVRLPG 5agv A 1.93 BS02 BU3 A 1 V188 E190 T389 D390 Y391 V179 E181 T377 D378 Y379 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPLNGNGPFPAVSTDYVYLLMPVRLPG 5agv A 1.93 BS03 BU3 A 2 A214 G218 V224 G244 N245 K247 A205 G209 V215 G235 N236 K238 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPLNGNGPFPAVSTDYVYLLMPVRLPG 5agv A 1.93 BS04 BU3 B 1 R16 L17 L18 E72 R7 L8 L9 E63 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPLNGNGPFPAVSTDYVYLLMPVRLPG 5agv B 1.93 BS01 III D 1 M163 R183 F184 R185 E257 P259 K260 L264 P362 M396 P397 V398 R399 M154 R174 F175 R176 E248 P250 K251 L255 P353 M387 P388 V389 R390 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG 5agv B 1.93 BS02 CA B 1 N379 G380 N370 G371 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG 5agv B 1.93 BS03 CA B 2 L33 P34 A35 L24 P25 A26 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG 5agv B 1.93 BS04 CA B 3 H269 R366 A386 V387 H260 R357 A377 V378 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG 5agv B 1.93 BS05 BU3 B 1 R16 L17 E72 P97 R7 L8 E63 P88 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG 5agv B 1.93 BS06 BU3 B 2 L33 G44 L24 G35 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG 5agv B 1.93 BS07 BU3 B 3 V188 E190 R262 T389 D390 Y391 V179 E181 R253 T380 D381 Y382 2.7.7.7 I6XU56 LTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG 5ah2 A 2.13 BS01 III E 1 M161 R181 F182 R183 P257 L262 M391 P392 V393 R394 M150 R170 F171 R172 P246 L251 M375 P376 V377 R378 2.7.7.7 A0QND6 TDLKFRVVREDFADAVAWVARSLPTRPTIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVSAEIASAGSVLVSGRLLSDITKALPAKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALPALPEETGVIASDLFAEAIGQVAVAAGRLPMLTGIRVEISGESVVLAATDRFRLAVRELTWVTTAGDVEAAVLVPAKTLAEAAKAGTDGNQVHLALGSGASVGKDGLLGIRSEGKRSTTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQIRMEFSDDTLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAVLRPAGEGGSGPFPAAKTDYVYLLMPVRLP 5ah2 C 2.13 BS01 III G 1 R181 F182 R183 Q261 L262 M391 P392 V393 R394 R173 F174 R175 Q253 L254 M377 P378 V379 R380 2.7.7.7 A0QND6 LTDLKFRVVREDFADAVAWVARSLPTPTIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVSAEIASAGSVLVSGRLLSDITKALPAKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALPALPEETGVIASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVRELTWVTTAGDVEAAVLVPAKTLAEAAKAGTDGNQVHLALGSGASVGKDGLLGIRSEGKRSTTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRAQIRMEFSDDTLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAVLRPAGEGGSGPFPAAKTDYVYLLMPVRLP 5ah4 A 2.31 BS01 III C 1 R181 F182 R183 E255 P257 K258 L262 P360 M391 P392 V393 R394 R169 F170 R171 E240 P242 K243 L247 P345 M375 P376 V377 R378 2.7.7.7 A0QND6 TDLKFRVVREDFADAVAWVARSLPTRVLAGVLLTGTDEGLTISGFDYEVSAEVKVSAEIASAGSVLVSGRLLSDITKALPAKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALPALPEETGVIASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVRELTWVTTAGDVEAAVLVPAKTLAEAAKAGNQVHLALGSGASVGKDGLLGIRSEGKRSTTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQIRMEFSDDTLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAVLRPAGEDDGAGGSGPFPAAKTDYVYLLMPVRLP 5ah4 B 2.31 BS01 III D 1 M161 L162 T179 R181 F182 R183 E255 K258 L262 P360 M391 P392 R394 M151 L152 T169 R171 F172 R173 E243 K246 L250 P348 M375 P376 R378 2.7.7.7 A0QND6 TDLKFRVVREDFADAVAWVARSLPTRIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVSAEIASAGSVLVSGRLLSDITKALPAKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALPALPEETGVIASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVRELTWVTTAGDVEAAVLVPAKTLAEAAKAGTNQVHLALGSGASVGKDGLLGIRSEGKRSTTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQIRMEFSDDTLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAVLRPAGEDGGSGPFPAAKTDYVYLLMPVRLP 5ahs A 2.30 BS01 FAD A 1 I121 I123 S124 G129 S130 Y153 W154 T156 E210 M361 I364 A365 G366 T368 Q370 I371 Q387 I120 I122 S123 G128 S129 Y152 W153 T155 E209 M360 I363 A364 G365 T367 Q369 I370 Q386 3.13.1.4 K4L7X3 YELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDKPAICISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARLMLRSAAVSGETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRTQVASKILDMKLPQTRDGY 5ahs A 2.30 BS02 COA A 1 S124 G129 S130 A237 M240 S241 Y243 N244 R247 I316 G366 G367 I371 K384 S123 G128 S129 A236 M239 S240 Y242 N243 R246 I315 G365 G366 I370 K383 3.13.1.4 K4L7X3 YELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDKPAICISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARLMLRSAAVSGETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRTQVASKILDMKLPQTRDGY 5ahs B 2.30 BS02 COA B 1 S124 S130 A132 A237 M240 S241 Y243 N244 R247 I316 G366 I371 K384 S123 S129 A131 A236 M239 S240 Y242 N243 R246 I315 G365 I370 K383 3.13.1.4 K4L7X3 YELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDKPAICISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARLMLRSAAVSGETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRTQVASKILDMKLPQTRDGY 5ahs D 2.30 BS02 COA D 1 S124 S130 A237 M240 S241 Y243 N244 R247 I316 G366 I371 K384 S122 S128 A235 M238 S239 Y241 N242 R245 I314 G364 I369 K382 3.13.1.4 K4L7X3 ELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDKPAICISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARLMLRSAAVSGETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRTQVASKILDMKLPQTRDGY 5ahs E 2.30 BS01 FAD E 1 R84 I121 I123 S124 G129 S130 Y153 W154 T156 E210 M361 A365 G366 G367 T368 Q370 I371 Q387 R83 I120 I122 S123 G128 S129 Y152 W153 T155 E209 M360 A364 G365 G366 T367 Q369 I370 Q386 3.13.1.4 K4L7X3 YELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDKPAICISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARLMLRSAAVSGETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRTQVASKILDMKLPQTRDGY 5ais B 1.85 BS01 CWC B 1 Y8 M11 G13 R14 Q36 D96 M99 W104 Y152 Y7 M10 G12 R13 Q35 D95 M98 W103 Y151 5.3.99.2,2.5.1.18 O60760 25978964 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 5ais C 1.85 BS01 CWC C 1 F9 M11 G13 R14 D96 M99 W104 Y152 F8 M10 G12 R13 D95 M98 W103 Y151 5.3.99.2,2.5.1.18 O60760 25978964 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 5ais D 1.85 BS01 CWC D 1 F9 M11 G13 R14 Q36 D96 M99 W104 Y152 L199 F8 M10 G12 R13 Q35 D95 M98 W103 Y151 L198 5.3.99.2,2.5.1.18 O60760 25978964 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 5aiv C 2.04 BS01 M1W C 1 M11 G13 R14 D96 M99 W104 Y152 C156 L199 M10 G12 R13 D95 M98 W103 Y151 C155 L198 5.3.99.2,2.5.1.18 O60760 25978964 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTENTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 5aix B 2.10 BS02 KRX B 1 F9 M11 G13 R14 Q36 M99 W104 A105 Y152 I155 C156 L199 F8 M10 G12 R13 Q35 M98 W103 A104 Y151 I154 C155 L198 5.3.99.2,2.5.1.18 O60760 25978964 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTENTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 5aix C 2.10 BS02 KRX C 1 F9 M11 G13 R14 Q36 M99 W104 Y152 I155 L199 F8 M10 G12 R13 Q35 M98 W103 Y151 I154 L198 5.3.99.2,2.5.1.18 O60760 25978964 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTENTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL 5aju A 2.50 BS01 RP5 A 1 G33 S34 M70 M128 R131 G154 Y155 G156 T157 E160 G10 S11 M47 M105 R108 G131 Y132 G133 T134 E137 26010010 PRAKICVFCGSSGGASPAHMEAARQLGRVMAENNIDLVYGGGTVGLMGEVARTVCSINGPESVHGIIPEALVRYERDGTYQTVKDNKQVVPTETVYGRTTVVKDMHTRKKMMAEEVISGGPGSGFIGLSGGYGTMEEVFEVITWNQLGIHTKGICLLNVEGYWDGILQWINMAAAQGFVQPGNETIVVSAGDAEGAVRALREYKVSEATFKLEWGRQ 5amq A 3.00 BS01 NUC B 1 H312 N313 P314 N318 A320 K323 K368 K370 A371 R372 Q377 I378 M379 N380 K381 K382 L383 W395 E396 Q397 Q398 L471 K472 Q506 T513 N517 S520 V521 Y524 R526 R531 M534 C535 A536 N537 N538 K859 K862 N1308 Q1313 S1314 I1511 L1512 F1513 H1515 K1516 H312 N313 P314 N318 A320 K323 K368 K370 A371 R372 Q377 I378 M379 N380 K381 K382 L383 W395 E396 Q397 Q398 L462 K463 Q497 T504 N508 S511 V512 Y515 R517 R522 M525 C526 A527 N528 N529 K834 K837 N1267 Q1272 S1273 I1453 L1454 F1455 H1457 K1458 A5HC98 26004069 MDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKHDLEVSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSADTVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMRLANNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALATEGYESNLGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDASILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNSPALVLRAYSKNNPDIQGAPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQIL 5amq A 3.00 BS02 NUC C 1 Q291 R292 K302 P303 H306 F418 C419 G420 K423 V437 S438 K439 P440 K441 R592 A593 R595 R600 T642 K643 Y677 K679 E758 H760 H761 V764 K768 L1113 Q1116 K1117 V1118 A1119 Y1120 D1123 Q291 R292 K302 P303 H306 F418 C419 G420 K423 V428 S429 K430 P431 K432 R577 A578 R580 R585 T627 K628 Y662 K664 E733 H735 H736 V739 K743 L1072 Q1075 K1076 V1077 A1078 Y1079 D1082 A5HC98 26004069 MDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKHDLEVSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSADTVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMRLANNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALATEGYESNLGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDASILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNSPALVLRAYSKNNPDIQGAPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQIL 5amq A 3.00 BS03 NUC c 1 M379 N380 I863 Q867 M379 N380 I838 Q842 A5HC98 26004069 MDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKHDLEVSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSADTVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMRLANNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALATEGYESNLGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDASILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNSPALVLRAYSKNNPDIQGAPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQIL 5amr A 2.57 BS01 NUC B 1 H312 N313 P314 N318 A320 K323 K368 K370 A371 R372 Q377 I378 M379 N380 K381 K382 L383 W395 E396 Q397 Q398 L471 K472 Q506 T513 N517 S520 V521 Y524 R526 R531 M534 C535 A536 N537 N538 K859 K862 K870 N1308 Q1313 I1511 L1512 F1513 H1515 K1516 H313 N314 P315 N319 A321 K324 K369 K371 A372 R373 Q378 I379 M380 N381 K382 K383 L384 W396 E397 Q398 Q399 L468 K469 Q503 T510 N514 S517 V518 Y521 R523 R528 M531 C532 A533 N534 N535 K846 K849 K857 N1261 Q1266 I1444 L1445 F1446 H1448 K1449 2.7.7.48 A5HC98 26004069 GMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKKQFKNKMLEDSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMRLANYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNEIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALLGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDSILTPRKFTGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINILGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNHHSPALVLRAYSNNPDIPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQIL 5amr A 2.57 BS02 NUC C 1 M379 N380 Q867 M380 N381 Q854 2.7.7.48 A5HC98 26004069 GMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKKQFKNKMLEDSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMRLANYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNEIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALLGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDSILTPRKFTGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINILGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNHHSPALVLRAYSNNPDIPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSTEHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQIL