2n0s A BS01 SF4 A 1 C130 P131 P184 C185 K188 C377 C381 C101 P102 P155 C156 K159 C333 C337 1.18.99.1 Q9FYU1 26010059 LSHVQQALAELAKPKDDPTRKHVCVQVAPAVRVAIAETLGLAPGATTPKQLAEGLRRLGFDEVFDTLFGADLTIMEEGSELLHRLTEHLEAEPLPMFTSCCPGWIAMLEKSYPDLIPYVSSCKSPQMMLAAMVKSYLAEKKGIAPKDMVMVSIMPCTRKQSEADRDWFCVDTRQLDHVITTVELGNIFKERGINLAELPEGEWDNPMGVGSGAGVLFGTTGGVMEAALRTAYELFTGTPLPRLSLSEVRGMDGIKETNITMVPAPGSKFEELLKHRAAGPLAWDGGAGFTSEDGRGGITLRVAVANGLGNAKKLITKMQAGEAKYDFVEIMACPAGCVGGGGQPRSTDKAITQKRQAALYNLDEKSTLRRSHENPSIRELYDTYLGEPLGHKAHELLHTHYVAGGV 2n0s B BS01 FES B 1 L23 P34 Y35 S36 C37 R38 C42 C45 C75 L23 P34 Y35 S36 C37 R38 C42 C45 C75 P07839 26010059 YKVTLKTPSGDKTIECPADTYILDAAEEAGLDLPYSCRAGACSSCAGKVAAGTVDQSDQSFLDDAQMGNGFVLTCVAYPTSDCTIQTHQEEALY 3wvj A 1.95 BS01 B3P A 1 V59 E140 Y154 E162 W215 V220 W223 V30 E111 Y125 E133 W186 V191 W194 3.2.1.73 A3DBX3 25765303 ATVVNTPFVAVFSNFDSSQWEKADWANGSVFNCVWKPSQVTFSNGKMILTLDREYGGSYPYKSGEYRTKSFFGYGYYEVRMKAAKNVGIVSSFFTYTGPSDNNPWDEIDIEFLGKDTTKVQFNWYKNGVGGNEYLHNLGFDASQDFHTYGFEWRPDYIDFYVDGKKVYRGTRNIPVTPGKIMMNLWPGIGVDEWLGRYDGRTPLQAEYEYVKYYPNGVP 3wvj A 1.95 BS02 B3P A 2 N56 F60 E94 F123 Y125 P128 W134 E136 M211 N213 N27 F31 E65 F94 Y96 P99 W105 E107 M182 N184 3.2.1.73 A3DBX3 25765303 ATVVNTPFVAVFSNFDSSQWEKADWANGSVFNCVWKPSQVTFSNGKMILTLDREYGGSYPYKSGEYRTKSFFGYGYYEVRMKAAKNVGIVSSFFTYTGPSDNNPWDEIDIEFLGKDTTKVQFNWYKNGVGGNEYLHNLGFDASQDFHTYGFEWRPDYIDFYVDGKKVYRGTRNIPVTPGKIMMNLWPGIGVDEWLGRYDGRTPLQAEYEYVKYYPNGVP 3wvj B 1.95 BS01 B3P B 1 W134 E140 Y154 E162 W223 W105 E111 Y125 E133 W194 3.2.1.73 A3DBX3 25765303 ATVVNTPFVAVFSNFDSSQWEKADWANGSVFNCVWKPSQVTFSNGKMILTLDREYGGSYPYKSGEYRTKSFFGYGYYEVRMKAAKNVGIVSSFFTYTGPSDNNPWDEIDIEFLGKDTTKVQFNWYKNGVGGNEYLHNLGFDASQDFHTYGFEWRPDYIDFYVDGKKVYRGTRNIPVTPGKIMMNLWPGIGVDEWLGRYDGRTPLQAEYEYVKYYPNGVPQ 3wvj B 1.95 BS02 B3P B 2 N56 F60 E94 F123 Y125 W134 E136 M211 N213 N27 F31 E65 F94 Y96 W105 E107 M182 N184 3.2.1.73 A3DBX3 25765303 ATVVNTPFVAVFSNFDSSQWEKADWANGSVFNCVWKPSQVTFSNGKMILTLDREYGGSYPYKSGEYRTKSFFGYGYYEVRMKAAKNVGIVSSFFTYTGPSDNNPWDEIDIEFLGKDTTKVQFNWYKNGVGGNEYLHNLGFDASQDFHTYGFEWRPDYIDFYVDGKKVYRGTRNIPVTPGKIMMNLWPGIGVDEWLGRYDGRTPLQAEYEYVKYYPNGVPQ 4ng4 A 2.78 BS01 MG A 1 D293 G319 F326 S327 T330 D284 G310 F317 S318 T321 2.7.2.3 Q83AU6 26033498 PFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKARVMILSHLGRPEEGKFEKEFSLAPVARLLSKKPLINDWLKGVAVEPGQAILCENVRFNKGENENNTELAKRMAELCDIFVMDAFATAHRAQASTAGVAAYAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGGGIANTFLKAQGYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKATVKNIDAVTSNESIFDVGPNTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKSTAYSIVGGGDTLAALDKFNLTDQMSYVSTAGGAFLEFLEGKLPAIKILTQRAK 4ng4 A 2.78 BS02 ADP A 1 G193 G194 S195 K200 G218 N222 L236 I291 N315 G316 P317 E322 G349 D350 T351 G184 G185 S186 K191 G209 N213 L227 I282 N306 G307 P308 E313 G340 D341 T342 2.7.2.3 Q83AU6 26033498 PFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKARVMILSHLGRPEEGKFEKEFSLAPVARLLSKKPLINDWLKGVAVEPGQAILCENVRFNKGENENNTELAKRMAELCDIFVMDAFATAHRAQASTAGVAAYAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGGGIANTFLKAQGYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKATVKNIDAVTSNESIFDVGPNTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKSTAYSIVGGGDTLAALDKFNLTDQMSYVSTAGGAFLEFLEGKLPAIKILTQRAK 4ng4 B 2.78 BS01 MG B 1 D293 G319 F326 S327 G329 T330 D288 G314 F321 S322 G324 T325 2.7.2.3 Q83AU6 26033498 PFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKARVMILSHLGRPEEGKFEKEFSLAPVARLLSKKLNKVPLINDWLKGVAVEPGQAILCENVRFNKGENENNTELAKRMAELCDIFVMDAFATAHRAQASTAGVAAYAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGGGIANTFLKAQGYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKATVKNIDAVTSNESIFDVGPNTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKSTAYSIVGGGDTLAALDKFNLTDQMSYVSTAGGAFLEFLEGKILPAIKILTQRAK 4ng4 B 2.78 BS02 ADP B 1 G193 G194 S195 K200 G218 N222 I291 N315 G316 P317 G319 V320 E322 G348 G349 D350 T351 G188 G189 S190 K195 G213 N217 I286 N310 G311 P312 G314 V315 E317 G343 G344 D345 T346 2.7.2.3 Q83AU6 26033498 PFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKARVMILSHLGRPEEGKFEKEFSLAPVARLLSKKLNKVPLINDWLKGVAVEPGQAILCENVRFNKGENENNTELAKRMAELCDIFVMDAFATAHRAQASTAGVAAYAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGGGIANTFLKAQGYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKATVKNIDAVTSNESIFDVGPNTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKSTAYSIVGGGDTLAALDKFNLTDQMSYVSTAGGAFLEFLEGKILPAIKILTQRAK 4ng4 C 2.78 BS02 ADP C 1 G194 S195 K200 G218 N222 L236 I291 N315 G316 P317 G319 E322 G348 G349 D350 T351 G188 S189 K194 G212 N216 L230 I285 N309 G310 P311 G313 E316 G342 G343 D344 T345 2.7.2.3 Q83AU6 26033498 PFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKARVMILSHLGRPEEGKFEKEFSLAPVARLLSKKLNVPLINDWLKGVAVEPGQAILCENVRFNKGENENNTELAKRMAELCDIFVMDAFATAHRAQASTAGVAAYAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGGGIANTFLKAQGYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKATVKNIDAVTSNESIFDVGPNTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKSTAYSIVGGGDTLAALDKFNLTDQMSYVSTAGGAFLEFLEGLPAIKILTQRAKEY 4odt H 1.95 BS01 GP1 H 1 Y32 G97 A98 Y100B Y32 G103 A104 Y108 EVQLVESGGGLVQPKGSLKLSCAASGFTFNTYAMNWVRQAPGKGLEWVARIRSKSNNYATYYADSVKDRFTISRDDSQSMLYLQMNNLKTEDTAMYYCVRHRGAPLYYGNGAWFAYWGQGTLVTVSAAKTTPPSVYPLAPGCGDTTGSSVTSGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSETVTCSVAHPASSTTVDKKLEP 4odt H 1.95 BS02 Z9M H 1 T31 Y32 A33 R52 H95 R96 G97 T31 Y32 A33 R52 H101 R102 G103 EVQLVESGGGLVQPKGSLKLSCAASGFTFNTYAMNWVRQAPGKGLEWVARIRSKSNNYATYYADSVKDRFTISRDDSQSMLYLQMNNLKTEDTAMYYCVRHRGAPLYYGNGAWFAYWGQGTLVTVSAAKTTPPSVYPLAPGCGDTTGSSVTSGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSETVTCSVAHPASSTTVDKKLEP 4odv L 2.15 BS01 GP1 L 1 R30 Y32 Y50 R30 Y32 Y50 DIVLTQSTSSLSASLGDRVTITCRASQDIRNYLSWYQQRPDGTVKLLIYYTSKLHSGVPSRFSGSGSGTDYSLTITNLEQEDIATYFCQQGKTLPLYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 4odv L 2.15 BS02 Z9M L 1 Y49 Y50 K53 Y49 Y50 K53 DIVLTQSTSSLSASLGDRVTITCRASQDIRNYLSWYQQRPDGTVKLLIYYTSKLHSGVPSRFSGSGSGTDYSLTITNLEQEDIATYFCQQGKTLPLYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 4odv H 2.15 BS01 GP1 L 1 N98 R100A N102 R105 EVKLVESGGGLVKLGGSLKLSCAASGFTFSSYYMSWVRQTPEKRLELVAAINSNGGNTYYPDTVKGLFTISRDNAKNTLYLQMSRLKSEDTALYYCTRLYGNYVRIHTMDYWGQGTSVTVSSAKTTPPSVYPLAPGCGDTTGSSVTLGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSETVTCSVAHPASSTTVDKKLEPS 4odv H 2.15 BS02 Z9M L 1 Y96 N98 H100C Y100 N102 H107 EVKLVESGGGLVKLGGSLKLSCAASGFTFSSYYMSWVRQTPEKRLELVAAINSNGGNTYYPDTVKGLFTISRDNAKNTLYLQMSRLKSEDTALYYCTRLYGNYVRIHTMDYWGQGTSVTVSSAKTTPPSVYPLAPGCGDTTGSSVTLGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSETVTCSVAHPASSTTVDKKLEPS 4p7u A 1.50 BS01 1PS A 1 C38 N40 Q41 W65 T109 F111 F126 C13 N15 Q16 W40 T84 F86 F101 2.7.11.30 P37173 26073093 ALCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPTCIMKEKKKPGETFFMCSCSSDECNDNIIFS 4qnk A 1.75 BS03 PO4 A 1 Q51 H55 K177 Q43 H47 K169 4.2.1.19 O23346 SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRR 4qpf A 1.59 BS01 39L A 1 F99 D103 D107 R112 T167 Q171 K200 T201 Y204 Q240 D243 K257 F86 D90 D94 R99 T154 Q158 K187 T188 Y191 Q227 D230 K244 2.5.1.10,2.5.1.1 P14324 VYAQEKQDFVQHFSQIVRVLTEPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 4r90 H 1.75 BS01 CA H 1 Y33 N35 D50 D99 P107 Y33 N35 D50 D99 P107 26018625 EVQLVESGGGLVQPGGSLRLSCAASGFTFSVYYMNWVRQAPGKGLEWVSDINNEGGTTYYADSVKGRFTISRDNAKNTLTLQMNSLKPEDTALYYCVRDAGYSNHVPIFDSWGQGTQVIVASASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 4rh3 A 3.02 BS01 ACP A 1 G33 G34 Y64 R97 C98 F101 R102 G127 D128 G129 S130 G133 L136 D177 G9 G10 Y40 R73 C74 F77 R78 G103 D104 G105 S106 G109 L112 D153 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEATTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4rh3 B 3.02 BS01 ACP B 1 G33 G34 R97 C98 F101 R102 G127 D128 G129 S130 G133 D177 G9 G10 R73 C74 F77 R78 G103 D104 G105 S106 G109 D153 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEATTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4rh3 C 3.02 BS01 ACP C 1 S32 G33 R97 C98 F101 R102 G127 D128 G129 S130 G133 L136 S8 G9 R73 C74 F77 R78 G103 D104 G105 S106 G109 L112 2.7.1.11 Q01813 SAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEATTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILA 4rm0 A 2.00 BS01 FUC A 1 T356 E358 N394 T136 E138 N174 Q6B7R3 KTKPFTLPILTIGELTNSRFPAPIDQLYTSPNADVVVQPQNGRCSLDGELQGTTQLLTTAICSYRGMTSNPTRDYWDGHLLHLVHPNGATYDPTEDVPAPFGTQDFRGILYGVLTQNPRASGDEAANSQGVYISSTSEKFTPKLGTIGLHQVQGNIASNQQSKFTPVGIAVNGNTPFRQWELPNYSGALTLNTNLAPAVGPNFPGEQILFFRSNVPSVQGGQPIEIDCLIPQEWVSHFYQESAPSQSDVALVRYVNPDTGRTIFEAKLHRQGFITIAATGSNPVVVPPNGYFRFDSWVNQFYALAPM 4rm0 A 2.00 BS02 GAL A 1 Y295 W296 S354 T356 S357 E358 N392 N394 T395 Y75 W76 S134 T136 S137 E138 N172 N174 T175 Q6B7R3 KTKPFTLPILTIGELTNSRFPAPIDQLYTSPNADVVVQPQNGRCSLDGELQGTTQLLTTAICSYRGMTSNPTRDYWDGHLLHLVHPNGATYDPTEDVPAPFGTQDFRGILYGVLTQNPRASGDEAANSQGVYISSTSEKFTPKLGTIGLHQVQGNIASNQQSKFTPVGIAVNGNTPFRQWELPNYSGALTLNTNLAPAVGPNFPGEQILFFRSNVPSVQGGQPIEIDCLIPQEWVSHFYQESAPSQSDVALVRYVNPDTGRTIFEAKLHRQGFITIAATGSNPVVVPPNGYFRFDSWVNQFYALAPM 4rm0 B 2.00 BS01 GAL B 1 W296 S354 T356 S357 N392 N394 T395 W75 S133 T135 S136 N171 N173 T174 Q6B7R3 TKPFTLPILTIGELTNSRFPAPIDQLYTSPNADVVVQPQNGRCSLDGELQGTTQLLTTAICSYRGMTSNPTRDYWDGHLLHLVHPNGATYDPTEDVPAPFGTQDFRGILYGVLTQNPRASGDEAANSQGVYISSTSEKFTPKLGTIGLHQVQGNIASNQQSKFTPVGIAVNGNTPFRQWELPNYSGALTLNTNLAPAVGPNFPGEQILFFRSNVPSVQGGQPIEIDCLIPQEWVSHFYQESAPSQSDVALVRYVNPDTGRTIFEAKLHRQGFITIAATGSNPVVVPPNGYFRFDSWVNQFYALAPM 4rvu A 1.80 BS01 NDP A 1 F41 Y45 L124 T128 Y131 A149 G152 G153 V154 V173 S174 K178 Y193 G219 V220 F241 G242 A243 A244 S245 R266 P267 S268 L269 L315 E316 R318 F42 Y46 L125 T129 Y132 A150 G153 G154 V155 V174 S175 K179 Y194 G220 V221 F242 G243 A244 A245 S246 R267 P268 S269 L270 L316 E317 R319 O53146 25924579 SMHAIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVGDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAINSEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP 4rxy A 1.90 BS01 ZN A 1 C42 H98 C101 C40 H96 C99 4.2.1.1 Q9HVB9 26068018 DLQQLFENNVRWAEAIKQEDPDFFAKLARQQTPEYLWIGCSDARVPANEIVGMLPGDLFVHRNVANVVLHTDLNCLSVIQFAVDVLKVKHILVTGHYGCGGVRASLHNDQLGLIDGWLRSIRDLAYEYREHLEQLPTEEERVDRLCELNVIQQVANVSHTSIVQNAWHRGQSLSVHGCIYGIKDGLWKNLNVTVSGLDQLPPQYRLSPL 4tqn A 1.70 BS01 UL4 A 1 L1109 P1110 V1115 L1120 I1122 N1168 R1173 V1174 L26 P27 V32 L37 I39 N85 R90 V91 2.3.1.48 Q92793 IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQS 4tqp A 1.58 BS01 48R A 1 K15 L17 P24 S52 K6 L8 P15 S43 P02766 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 4tvr A 2.29 BS01 ZN A 1 C331 C334 C342 C345 C165 C168 C176 C179 6.3.2.- Q96PU4 TSARARLIDPGFGIYKVNELVDARDVGLGAWFEAHIHSVTRADEDVIYHIQYDEYPESGTLEMNVKDLRPRARTILKWNELNVGDVVMVNYNVESPGQRGFWFDAEITTLKTISRTKKELRVKIFLGTLNDCKIISVDEIFKIERPGAHPLSFADGKFLRRNDPCDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNPPLDKVWYCPSCK 4tvr A 2.29 BS02 ZN A 2 C347 C350 H370 C373 C181 C184 H204 C207 6.3.2.- Q96PU4 TSARARLIDPGFGIYKVNELVDARDVGLGAWFEAHIHSVTRADEDVIYHIQYDEYPESGTLEMNVKDLRPRARTILKWNELNVGDVVMVNYNVESPGQRGFWFDAEITTLKTISRTKKELRVKIFLGTLNDCKIISVDEIFKIERPGAHPLSFADGKFLRRNDPCDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNPPLDKVWYCPSCK 4tvr A 2.29 BS03 ZN A 3 C362 C365 C389 C196 C199 C218 6.3.2.- Q96PU4 TSARARLIDPGFGIYKVNELVDARDVGLGAWFEAHIHSVTRADEDVIYHIQYDEYPESGTLEMNVKDLRPRARTILKWNELNVGDVVMVNYNVESPGQRGFWFDAEITTLKTISRTKKELRVKIFLGTLNDCKIISVDEIFKIERPGAHPLSFADGKFLRRNDPCDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNPPLDKVWYCPSCK 4ua7 A 0.89 BS01 3GK A 1 N104 Y105 S130 N132 P167 N170 T171 T235 G236 S237 G238 D240 N78 Y79 S104 N106 P141 N144 T145 T209 G210 S211 G212 D213 H6UQI0 26057252 TSAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAEGL 4ua7 A 0.89 BS02 3GK A 2 N104 Y105 S237 S274 R276 N78 Y79 S211 S246 R248 H6UQI0 26057252 TSAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAEGL 4uaa A 0.86 BS02 3GK A 2 N104 Y105 T216 S237 S274 R276 N78 Y79 T190 S211 S246 R248 H6UQI0 26057252 TSAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAEGL 4ub9 A 2.27 BS01 ZN A 1 H282 H302 H253 H273 G2XLB0 25905461 FFEGETIAIVGGTLIDGNGGVPVPETTVFIEDGRITKVGSTDQIEVHPNIRQIDAQGKWILPGLVNGNVHLLDGIMMMGRGGIEYLARFEGNYYKVIEEAAQIALRGGVTTVFDTWNALEPVTIARDRIASGAAEGARIFFAGTLIGMGGPFTGDFMRPSMQARTVMSRTFADRMDAMFEVGMGRHLSTLPPAEVRPLIREYLERGVDFCKIAVTDHLVGLLGFRAPYFTFSERVLDVLVDEVRRAGVPLLTHTTSLEGLNTAIERDADLMIHATMTGQAPIPEETIEKLLEKQLWSEVQPTTIAQQAWMDSVDHPFADFSGRVHHENDVRMIKAGVPLVLGTDAGCTDPDILEDMSQGELHERPWTLGEDHFVWMQAMVEKGMDPMAAILAGTANPAKAYRKFDELGSIDVGKLGDVVVLDQDPLADITNMRTLSHVVKEGREIDFHGLPLSPLVTAYPRTANVLD 4udu C 2.50 BS01 ZN C 1 H187 H225 D227 H172 H210 D212 P12993 KDLRKKSELQRNALSNLRQIYYYNEKAITENKESNTLLFKGFFTGHPWYNDLLVDLGSKDATNKYKGKKVDLYGAYYGYQCAGGTPNKTACMYGGVTLHDNNRLTEEKKVPINLWIDGKQTTVPIDKVKTSKKEVTVQELDLQARHYLHGKFGLYNSDSFGGKVQRGLIVFHSSEGSTVSYDLFDAQGQYPDTLLRIYRDNKTINSENLHIDLYLYTT 4ug5 A 2.35 BS01 HEM A 1 W60 S63 R65 C66 I67 M221 F235 N236 G237 W238 M240 E243 W329 Y355 W59 S62 R64 C65 I66 M220 F234 N235 G236 W237 M239 E242 W328 Y354 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ug5 A 2.35 BS03 XFK A 1 R65 I218 F235 W238 E243 W329 Y357 R64 I217 F234 W237 E242 W328 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ug6 A 1.81 BS03 XFJ A 1 I218 F235 G237 W238 E243 W329 Y357 I217 F234 G236 W237 E242 W328 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ug6 A 1.81 BS05 POL A 2 G144 D166 Y255 K257 G143 D165 Y254 K256 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ug7 A 1.76 BS01 HEM A 1 W60 C66 I67 M221 F235 N236 G237 W238 M240 E243 V300 W329 Y355 W59 C65 I66 M220 F234 N235 G236 W237 M239 E242 V299 W328 Y354 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ug7 A 1.76 BS03 1EV A 1 R65 Q129 R132 I218 F235 G237 W238 Y239 E243 N248 R254 W329 Y357 R64 Q128 R131 I217 F234 G236 W237 Y238 E242 N247 R253 W328 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ug8 A 1.89 BS01 HEM A 1 W60 S63 R65 C66 I67 L75 F235 N236 G237 W238 M240 E243 V300 W329 Y355 Y357 W59 S62 R64 C65 I66 L74 F234 N235 G236 W237 M239 E242 V299 W328 Y354 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ug8 A 1.89 BS03 HW1 A 1 H128 I218 D220 F235 N236 G237 W238 Y239 E243 W329 Y357 H127 I217 D219 F234 N235 G236 W237 Y238 E242 W328 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ug9 A 1.84 BS02 1EW A 1 H128 Q129 I218 F235 G237 W238 Y239 E243 R247 W329 H127 Q128 I217 F234 G236 W237 Y238 E242 R246 W328 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugc A 1.80 BS03 1Q6 A 1 Q129 I218 F235 N236 G237 W238 Y239 E243 W329 Q128 I217 F234 N235 G236 W237 Y238 E242 W328 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugd A 2.03 BS03 Q14 A 1 I218 F235 N236 G237 W238 Y239 E243 W329 Y357 I217 F234 N235 G236 W237 Y238 E242 W328 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4uge A 2.14 BS03 Q15 A 1 H128 Q129 I218 D220 M221 F235 G237 W238 Y239 E243 Y357 K360 H127 Q128 I217 D219 M220 F234 G236 W237 Y238 E242 Y356 K359 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugf A 1.81 BS03 Q16 A 1 R65 H128 I218 F235 W238 Y239 E243 W329 Y357 R64 H127 I217 F234 W237 Y238 E242 W328 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugf A 1.81 BS04 POL A 1 R142 G144 D166 R254 Y255 R141 G143 D165 R253 Y254 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugg A 2.36 BS01 HEM A 1 W60 S63 R65 C66 I67 P108 M221 F235 N236 G237 W238 M240 E243 V300 W329 Y355 W59 S62 R64 C65 I66 P107 M220 F234 N235 G236 W237 M239 E242 V299 W328 Y354 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugg A 2.36 BS03 S5D A 1 R65 H128 Q129 I218 F235 W238 Y239 E243 W329 Y357 R64 H127 Q128 I217 F234 W237 Y238 E242 W328 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugh A 1.99 BS03 4V4 A 1 H128 Q129 I218 F235 G237 W238 E243 Y357 H127 Q128 I217 F234 G236 W237 E242 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugi A 1.80 BS01 HEM A 1 W60 S63 R65 C66 F235 N236 G237 W238 E243 Y355 Y357 W59 S62 R64 C65 F234 N235 G236 W237 E242 Y354 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugi A 1.80 BS02 SKO A 1 H128 P216 I218 M221 F235 N236 G237 W238 Y239 E243 W329 Y357 H127 P215 I217 M220 F234 N235 G236 W237 Y238 E242 W328 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugi A 1.80 BS03 POL A 1 G144 R254 Y255 G143 R253 Y254 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugi A 1.80 BS04 POL A 2 D79 R81 D82 D78 R80 D81 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugj A 1.78 BS03 Q1T A 1 H128 Q129 R132 I218 F235 N236 G237 W238 Y239 E243 N248 R254 W329 H127 Q128 R131 I217 F234 N235 G236 W237 Y238 E242 N247 R253 W328 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugk A 1.62 BS01 HEM A 1 W60 C66 I67 I218 F235 N236 G237 W238 M240 E243 V300 W329 Y355 Y357 W59 C65 I66 I217 F234 N235 G236 W237 M239 E242 V299 W328 Y354 Y356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugk A 1.62 BS03 7S9 A 1 H128 Q129 P216 I218 F235 N236 G237 W238 E243 H127 Q128 P215 I217 F234 N235 G236 W237 E242 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugm A 2.09 BS03 1QE A 1 H128 P216 I218 D220 F235 N236 G237 W238 E243 Y357 Q358 K360 H127 P215 I217 D219 F234 N235 G236 W237 E242 Y356 Q357 K359 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugn A 2.09 BS03 H49 A 1 H128 P216 I218 F235 N236 G237 W238 E243 H127 P215 I217 F234 N235 G236 W237 E242 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugo A 2.38 BS03 1QF A 1 H128 R132 P216 I218 F235 N236 G237 W238 E243 Y357 K360 H127 R131 P215 I217 F234 N235 G236 W237 E242 Y356 K359 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugp A 1.80 BS03 I5U A 1 H128 P216 I218 F235 N236 G237 W238 E243 W329 H127 P215 I217 F234 N235 G236 W237 E242 W328 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugq A 1.85 BS03 7LN A 1 H128 P216 I218 F235 N236 G237 W238 E243 Y357 Q358 H127 P215 I217 F234 N235 G236 W237 E242 Y356 Q357 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugr A 2.09 BS03 6E5 A 1 I125 W126 H128 A147 P216 I218 D220 F235 N236 G237 W238 E243 Q358 K360 P361 I124 W125 H127 A146 P215 I217 D219 F234 N235 G236 W237 E242 Q357 K359 P360 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4ugv A 1.98 BS03 ARG A 1 Q129 Y213 W238 Y239 E243 N248 Q128 Y212 W237 Y238 E242 N247 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFFQDKPYE 4ugw A 1.90 BS03 HW1 A 1 R65 H128 I218 F235 G237 W238 Y239 E243 W329 F357 R64 H127 I217 F234 G236 W237 Y238 E242 W328 F356 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFFQDKPYE 4ugy A 1.80 BS03 EXI A 1 H128 Q129 P216 I218 F235 N236 G237 W238 Y239 E243 N248 R254 H127 Q128 P215 I217 F234 N235 G236 W237 Y238 E242 N247 R253 1.14.13.165 O34453 26062720 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4unq A 2.30 BS01 H6D A 1 P37 Y39 L52 M66 F70 R74 R95 S99 N100 Y103 S104 R107 P37 Y39 L52 M66 F70 R74 R95 S99 N100 Y103 S104 R107 2.7.4.9 25486447 MLIAIEGVDGAGKRTLVEKLSGAFRAAGRSVATLAFPRYGQSVAADIAAEALHGEHGDLASSVYAMATLFALDRAGAVHTIQGLCRGYDVVILDRYVASNAAYSAARLHENAAGKAAAWVQRIEFARLGLPKPDWQVLLAVSAEDAELQQRTGAVYAELAAQGWGGRWLVVGADVDPGRLAATLAP 4uol A 3.30 BS01 GLY A 1 F225 T227 D228 E229 L938 F176 T178 D179 E180 L886 4.1.1.31 P04711 EYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKLSDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 4uol A 3.30 BS02 GLY A 2 H177 E566 S602 D603 R759 R773 A774 I775 H128 E517 S553 D554 R710 R724 A725 I726 4.1.1.31 P04711 EYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKLSDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 4uol A 3.30 BS03 GLY B 1 W333 R334 W284 R285 4.1.1.31 P04711 EYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKLSDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 4uol B 3.30 BS02 GLY B 1 S100 F225 E229 S65 F176 E180 4.1.1.31 P04711 EYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKESDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 4uol B 3.30 BS03 GLY B 2 H177 R456 E566 D603 R759 R773 H128 R407 E517 D554 R710 R724 4.1.1.31 P04711 EYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKESDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 4uol C 3.30 BS01 GLY C 1 F225 T227 E229 F176 T178 E180 4.1.1.31 P04711 IEYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKSDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 4uol D 3.30 BS02 GLY D 1 S100 F225 T227 E229 L938 S65 F175 T177 E179 L885 4.1.1.31 P04711 EYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKSDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 4uol D 3.30 BS03 GLY D 2 H177 R456 E566 S602 D603 R759 R773 A774 H127 R406 E516 S552 D553 R709 R723 A724 4.1.1.31 P04711 EYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKSDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQDEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYIDQIEELMFELSMWRCNDELRVRAEELHSSSGSKVTKYYIEFWKQIPPNEPYRVILGHVRDKLYNTRERARHLLASGVSEISAESSFTSIEEFLEPLELCYKSLCDCGDKAIADGSLLDLLRQVFTFGLSLVKLDIRQESERHTDVIDAITTHLGIGSYREWSEDKRQEWLLSELRGKRPLLPPDLPQTEEIADVIGAFHVLAELPPDSFGPYIISMATAPSDVLAVELLQRECGVRQPLPVVPLFERLADLQSAPASVERLFSVDWYMDRIKGKQQVMVGYSDSGKDAGRLSAAWQLYRAQEEMAQVAKRYGVKLTLFHGRGGTVGRGGGPTHLAILSQPPDTINGSIRVTVQGEVIEFCFGEEHLCFQTLQRFTAATLEHGMHPPVSPKPEWRKLMDEMAVVATEEYRSVVVKEARFVEYFRSATPETEYGRMNIGSRPAKRRPGGGITTLRAIPWIFSWTQTRFHLPVWLGVGAAFKFAIDKDVRNFQVLKEMYNEWPFFRVTLDLLEMVFAKGDPGIAGLYDELLVAEELKPFGKQLRDKYVETQQLLLQIAGHKDILEGDPFLKQGLVLRNPYITTLNVFQAYTLKRIRDPNFKVTPQPPLSKEFADEAGLVKLNPASEYPPGLEDTLILTMKGIAAGMQNTG 4uqa A 1.52 BS01 HIS A 1 W81 E136 W143 Y200 E225 Y227 W264 W86 E141 W148 Y205 E230 Y232 W269 3.2.1.8 SHMASATINLSAEKQVIRGFGGMNHPVWISDLTPQQRDTAFGNGEGQLGFTILRIHVDENRNNWSKEVATARRAIELGAIVSASPWNPPSNMVETFTRNGVPNQKRLRYDKYGDYVQHLNDFVAYMKSNGVDLYAISVQNEPDYAHEWTWWTPQEMLRFMRDYAGQIRCRVMAPESFQYLKNMSDPILNDPQALANLDILGAHFYGTTVNNMPYPLFEQKGAGKELWMTEVYVPNSDSNSADRWPEALEVAHNMHNALVEGNFQAYVWWYIRRSYGPMKEDGTISKRGYMMAHYSKFVRPGYVRVDATKNPTYNVYLSACKNKKDNSVVAVVINKSTEAKTINISVPGTSIRKWERYVTTGSKNLRKESDINASGTTFQVTLEPQSVTTFV 4uqc A 1.30 BS01 GLC A 1 E136 Y139 F172 Y200 Y227 E140 Y143 F176 Y204 Y231 3.2.1.8 HMASATINLSAEKQVIRGFGGMNHPVWISDLTPQQRDTAFGNGEGQLGFTILRIHVDENRNNWSKEVATARRAIELGAIVSASPWNPPSNMVETFTRNGVPNQKRLRYDKYGDYVQHLNDFVAYMKSNGVDLYAISVQNEPDYAHEWTWWTPQEMLRFMRDYAGQINCRVMAPESFQYLKNMSDPILNDPQALANLDILGAHFYGTTVNNMPYPLFEQKGAGKELWMTEVYVPNSDSNSADRWPEALEVAHNMHNALVEGNFQAYVWWYIRRSYGPMKEDGTISKRGYMMAHYSKFVRPGYVRVDATKNPTYNVYLSACKNKKDNSVVAVVINKSTEAKTINISVPGTSIRKWERYVTTGSKNLRKESDINASGTTFQVTLEPQSVTTFV 4wco A 2.46 BS01 ZN A 1 D104 D109 D34 D39 Q9UHP7 25826155 LQAACPESWIGFQRKCFYFSDDTKNWTSSQRFCDSQDADLAQVESFQELNFLLRYKGPSDHWIGLSREQGQPWKWINGTEWTRQFPILGAGECAYLNDKGASSARCYTERKWICSKS 4wdi A 2.31 BS01 III C 1 Y7 V9 Q63 R66 D70 W73 V76 S77 T80 Y84 R97 F99 F116 T143 K146 W147 A150 D152 Y155 Y156 Y159 E163 W167 Y171 Y8 V10 Q64 R67 D71 W74 V77 S78 T81 Y85 R98 F100 F117 T144 K147 W148 A151 D153 Y156 Y157 Y160 E164 W168 Y172 MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRWKP 4wdi D 2.31 BS01 III F 1 Y7 V9 F22 A24 E62 Q63 R66 S69 D70 W73 V76 S77 T80 Y84 R97 F99 F116 T143 K146 W147 A150 D152 Y155 Y156 Y159 W167 Y171 Y8 V10 F23 A25 E63 Q64 R67 S70 D71 W74 V77 S78 T81 Y85 R98 F100 F117 T144 K147 W148 A151 D153 Y156 Y157 Y160 W168 Y172 MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRWKP 4xal A 1.87 BS01 III B 1 H62 A66 L70 T90 I91 R92 V93 T94 V95 C96 E97 H42 A46 L50 T70 I71 R72 V73 T74 V75 C76 E77 P10233 26068188 QSMRKLHFSTAPPNPDAPWTPRVAGFNKRVFCAAVGRLAAMHARMAAVQLWDMSRPRTDEDLNELLGITTIRVTVCEGKNLLQRANELVN 4xch A 2.20 BS01 ZN A 1 H57 H61 C127 H46 H50 C116 4.4.1.21 B2CMA5 LDHTIVKAPYIRLISEEVGPKGDIITNFDIRLIQPNENAMDTAGLHTIEHLLAKLIRQRIDGLIDCSPFGCRTGFHMIMWGKQDSEKIAQVIKSSLEEIAEGITWEDVPGTTIESCGNYKDHSLHSAKEWAKLILSQGISTDAFERKPI 4xjj A 1.40 BS01 41D A 1 C38 Q41 W65 F111 F126 C13 Q16 W40 F86 F101 2.7.11.30 P37173 ALCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPTCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEY 4xsg A 1.80 BS01 GSP A 1 G14 A15 C16 G17 K18 T19 C20 F30 T37 G62 K118 D120 L121 S160 A161 K162 G11 A12 C13 G14 K15 T16 C17 F27 T34 G59 K115 D117 L118 S157 A158 K159 P61586 26067270 IRKKLVIVGDGACGKTCLLIVNSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL 4xsh B 2.50 BS01 NAI B 1 A51 R52 N55 R59 R97 G98 D99 D100 W102 I103 E137 S142 T143 S144 Y151 R155 Q183 E185 A37 R38 N41 R45 R83 G84 D85 D86 W88 I89 E123 S128 T129 S130 Y137 R141 Q169 E171 Q8KNY0 26067270 KYKLCTNKEEADAWGKKQFNKWSKEEKSAIRDYTKNARPYNEFLRMHAGKLDSDPTMKKKIESLDKALNRKEAKVNDNIKVYRGDDAWIFGKEYDNSIIKNGKVDREKFKEIQKKFQGKTTTEFGYISTSILIDAGYAKTRPVMTEFKVGSGTHGAYMNSDDLTAYPGQYELLLPRNTVYKIEKIYIAIDNNTQKEQIKVEATIK 4xyp A 2.10 BS01 MBT A 1 Y357 L358 Y50 L51 V5RD79 VKEKLNGIIDQINKVNLLLEGEIEAVRRIAYMNQASSLQNQVEIGLIGEYLNISSWLETKTLTKTEEGLM 4yab A 1.90 BS03 4CN A 1 A923 F924 V928 V932 Y935 N980 V986 A95 F96 V100 V104 Y107 N152 V158 6.3.2.- O15164 26061247 SPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4yab B 1.90 BS03 4CN B 1 A923 F924 V928 P929 V932 Y935 N980 A91 F92 V96 P97 V100 Y103 N148 6.3.2.- O15164 26061247 PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4yad A 1.73 BS03 4A7 A 1 A923 F924 V928 P929 V932 Y935 F979 N980 V986 A95 F96 V100 P101 V104 Y107 F151 N152 V158 6.3.2.- O15164 26061247 PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4yat A 2.18 BS03 4A8 A 1 L922 A923 F924 V928 P929 V932 N980 L90 A91 F92 V96 P97 V100 N147 6.3.2.- O15164 26061247 PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4yat B 2.18 BS03 4A8 B 1 L922 A923 F924 V928 P929 V932 Y935 F979 N980 L90 A91 F92 V96 P97 V100 Y103 F145 N146 6.3.2.- O15164 26061247 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQESMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4yax A 2.25 BS01 4AE A 1 L922 A923 F924 V928 P929 V932 F979 N980 V986 L96 A97 F98 V102 P103 V106 F153 N154 V160 6.3.2.- O15164 26061247 SPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4yax B 2.25 BS03 4AE B 1 A923 V928 P929 V932 F979 N980 V986 A95 V100 P101 V104 F151 N152 V158 6.3.2.- O15164 26061247 PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4ybm B 1.46 BS01 4BJ B 1 L930 Y936 T947 R951 Y956 M958 L94 Y100 T111 R115 Y120 M122 6.3.2.- O15164 26061247 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4ybm B 1.46 BS02 4BJ B 2 L922 A923 V928 P929 V932 F979 N980 E985 V986 L86 A87 V92 P93 V96 F143 N144 E149 V150 6.3.2.- O15164 26061247 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4ybs A 1.83 BS03 4BK A 1 A923 F924 V928 V932 F979 N980 E985 V986 A989 A95 F96 V100 V104 F151 N152 E157 V158 A161 6.3.2.- O15164 26061247 PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4ybt A 1.82 BS03 4BV A 1 L922 A923 F924 V928 P929 V932 Y935 F979 N980 E985 V986 A989 L94 A95 F96 V100 P101 V104 Y107 F151 N152 E157 V158 A161 6.3.2.- O15164 26061247 PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4yc9 A 1.82 BS03 4C1 A 1 A923 F924 Q925 D926 V928 P929 V932 F979 N980 E985 V986 A97 F98 Q99 D100 V102 P103 V106 F153 N154 E159 V160 6.3.2.- O15164 26061247 SPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP 4ycv A 3.41 BS01 KRS A 1 R330 E332 T337 H338 N339 F342 E500 V501 N503 L555 R559 I570 R248 E250 T255 H256 N257 F260 E418 V419 N421 L459 R463 I474 6.1.1.6 W7JP72 26074468 VDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSAQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYGLKDTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFKLLDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRP 4ycv B 3.41 BS01 KRS B 1 R330 H338 N339 F342 S344 E500 V501 G556 R559 R252 H260 N261 F264 S266 E422 V423 G461 R464 6.1.1.6 W7JP72 26074468 EVDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSAQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYGLKDTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRP 4ycv C 3.41 BS01 KRS C 1 R330 H338 N339 F342 E500 V501 L502 N503 G554 L555 R559 R250 H258 N259 F262 E420 V421 L422 N423 G458 L459 R463 6.1.1.6 W7JP72 26074468 VDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKELSIFPKETILLSACLHMLPMKYGLKDTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFLDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRP 4ycv D 3.41 BS01 KRS D 1 R330 H338 N339 F342 E500 V501 G554 G556 R559 R246 H254 N255 F258 E416 V417 G452 G454 R457 6.1.1.6 W7JP72 26074468 DPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSAGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKGELSIFPKETILLSACLHMLPMKYGLKDTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLINARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRP 4yef G 1.72 BS01 GLU G 1 F82 L116 D117 L118 H123 F4 L38 D39 L40 H44 P80386 25774984 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSQNNFVAILDLPEGHQYKFFVDGQWTHDPSEPIVTSQLGTVNNII 4yef G 1.72 BS02 4CQ G 1 K89 W100 K126 Q132 W133 S144 Q145 L146 T148 N150 K11 W22 K47 Q53 W54 S65 Q66 L67 T69 N71 P80386 25774984 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSQNNFVAILDLPEGHQYKFFVDGQWTHDPSEPIVTSQLGTVNNII 4ymk A 2.61 BS01 ZN A 1 H116 H121 H153 H157 H297 H77 H82 H114 H118 H258 1.14.19.1 P13516 EDIRPEMKEDIHDPTYQDEEGPPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTFPFDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSHKSSENLYFQ 4ymk A 2.61 BS02 ZN A 2 H156 H265 H294 H298 H117 H226 H255 H259 1.14.19.1 P13516 EDIRPEMKEDIHDPTYQDEEGPPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTFPFDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSHKSSENLYFQ 4ymk A 2.61 BS03 ST9 A 1 V68 N71 A108 I111 T112 H116 F142 Q143 N144 W149 R151 D152 H153 W180 L181 V183 R184 K185 V189 G193 G194 T257 W258 V260 N261 A288 E291 V29 N32 A69 I72 T73 H77 F103 Q104 N105 W110 R112 D113 H114 W141 L142 V144 R145 K146 V150 G154 G155 T218 W219 V221 N222 A249 E252 1.14.19.1 P13516 EDIRPEMKEDIHDPTYQDEEGPPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTFPFDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSHKSSENLYFQ 4ymk A 2.61 BS04 MPG A 1 C97 G100 Y104 M105 L252 L286 V289 C58 G61 Y65 M66 L213 L247 V250 1.14.19.1 P13516 EDIRPEMKEDIHDPTYQDEEGPPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTFPFDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSHKSSENLYFQ 4ymk D 2.61 BS03 ST9 D 1 V68 N71 A108 I111 T112 H116 F142 Q143 N144 W149 R151 D152 H153 W180 L181 V183 R184 K185 V189 K190 G193 G194 L254 T257 W258 V260 N261 G287 A288 E291 V28 N31 A68 I71 T72 H76 F102 Q103 N104 W109 R111 D112 H113 W140 L141 V143 R144 K145 V149 K150 G153 G154 L214 T217 W218 V220 N221 G247 A248 E251 1.14.19.1 P13516 DIRPEMKEDIHDPTYQDEEGPPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTFPFDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSH 4ymk D 2.61 BS04 MPG D 1 V89 C97 G100 I101 Y104 M105 L252 L286 V289 V49 C57 G60 I61 Y64 M65 L212 L246 V249 1.14.19.1 P13516 DIRPEMKEDIHDPTYQDEEGPPPKLEYVWRNIILMVLLHLGGLYGIILVPSCKLYTCLFGIFYYMTSALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTFPFDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSH 4ynn A 3.20 BS01 III I 1 E61 S62 I63 H81 I172 N186 A190 T206 A207 I208 S210 E25 S26 I27 H45 I136 N150 A154 T170 A171 I172 S174 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn A 3.20 BS02 III Q 1 L244 M245 I247 F248 V249 V305 L208 M209 I211 F212 V213 V269 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn B 3.20 BS01 III J 1 I63 H81 I172 G188 A190 T206 A207 I208 I209 I26 H44 I135 G151 A153 T169 A170 I171 I172 3.4.21.- Q5ZVV9 PSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn B 3.20 BS02 III R 1 M245 I247 F248 V249 V305 M208 I210 F211 V212 V268 3.4.21.- Q5ZVV9 PSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn C 3.20 BS01 III K 1 I63 H81 I172 P187 A190 T206 A207 I208 I209 S210 I27 H45 I136 P151 A154 T170 A171 I172 I173 S174 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn C 3.20 BS02 III S 1 L244 M245 I247 F248 V249 I309 L208 M209 I211 F212 V213 I273 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn D 3.20 BS01 III L 1 S62 I63 H81 A190 T206 A207 I208 I209 S210 S26 I27 H45 A154 T170 A171 I172 I173 S174 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn D 3.20 BS02 III T 1 I247 F248 V305 K306 I211 F212 V269 K270 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn E 3.20 BS01 III M 1 I63 H81 I172 N186 A190 T206 A207 I208 I209 S210 I27 H45 I136 N150 A154 T170 A171 I172 I173 S174 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn F 3.20 BS01 III N 1 I63 H81 I172 N186 G188 A190 T206 A207 I208 S210 I27 H45 I136 N150 G152 A154 T170 A171 I172 S174 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn G 3.20 BS01 III O 1 E61 S62 I63 H81 I172 N186 P187 G188 N189 A190 T206 A207 I208 E25 S26 I27 H45 I136 N150 P151 G152 N153 A154 T170 A171 I172 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn G 3.20 BS02 III U 1 I247 F248 V249 V305 I211 F212 V213 V269 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4ynn H 3.20 BS02 III V 1 L244 M245 I247 F248 V249 K306 L208 M209 I211 F212 V213 K270 3.4.21.- Q5ZVV9 MPSLAPVLKNAMPAIVNVAVQGYFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVLRGAGALYLLII 4yoz A 2.25 BS01 III B 1 Y849 K853 V854 T860 F861 Q862 D929 I931 Y934 N935 Y276 K280 V281 T287 F288 Q289 D316 I318 Y321 N322 P28749 25917549 EFTQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNRPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKERGDLIKFYNTIYVGRVKSFALKYPLSPFP 4ysb A 2.50 BS01 FE A 1 H57 H112 D129 H57 H112 D129 Q1D4C9 MIFRQLFDSESSTYTYLIGDEATRQAVLIDPVLEQVDRDLQMVAELDLTLTHVFDTHVHADHITASGALRERTQATVVGSVNGASCANVQVRHGDEVRVGQLVFQVLATPGHTDDSISYLLGDRVFTGDALLVRGNGRTDFQNGNASQLYDSLTRVLFTLPDETLVYPGHDYKGRTVTSIAEEKRHNPRVAGKSREEFIHIMENLNLPRPKLIDAAVPANRACGH 4ysk A 2.47 BS01 FE A 1 H74 D78 H149 D170 H74 D78 H149 D170 A5VWI3 MIIGNNLHVDAFYDEATSTISYLVMDRETRQCALIDSVLDYDPKSGRTCSASADRLVERVNELNASVRWVLETHVHADHLSAAAYLKEKLGGHTAIGAHITQVQKVFGALFNAEPGFARDGSQFDVLLEDEEGFRIGNLQARALHTPGHTPACMSFMIEDAGEIAVFVGDTLFMPDYGTARCDFPGADARTLYRSIRRLLAFPDQTRLFMCHDYLPGGRDMQYVTTVAEQRASNIHIHQGIDEDSFVAMREARDKTLEMPVLILPSVQVNMRSGQLPPPEANGVSYLKIPLNKL 4ysl A 1.46 BS01 FE A 1 H74 H149 D170 H74 H149 D170 A5VWI3 MIIGNNLHVDAFYDEATSTISYLVMDRETRQCALIDSVLDYDPKSGRTCSASADRLVERVNELNASVRWVLETHVHADHLSAAAYLKEKLGGHTAIGAHITQVQKVFGALFNAEPGFARDGSQFDVLLEDEEGFRIGNLQARALHTPGHTPACMSFMIEDAGEIAVFVGDTLFMPDYGTARCDFPGADARTLYRSIRRLLAFPDQTRLFMCHDYLPGGRDMQYVTTVAEQRASNIHIHQGIDEDSFVAMREARDKTLEMPVLILPSVQVNMRSGQLPPPEANGVSYLKIPLNKL 4ysl A 1.46 BS02 GSH A 1 H149 D170 F173 Y177 A180 R181 Y214 R250 R253 P260 V261 H149 D170 F173 Y177 A180 R181 Y214 R250 R253 P260 V261 A5VWI3 MIIGNNLHVDAFYDEATSTISYLVMDRETRQCALIDSVLDYDPKSGRTCSASADRLVERVNELNASVRWVLETHVHADHLSAAAYLKEKLGGHTAIGAHITQVQKVFGALFNAEPGFARDGSQFDVLLEDEEGFRIGNLQARALHTPGHTPACMSFMIEDAGEIAVFVGDTLFMPDYGTARCDFPGADARTLYRSIRRLLAFPDQTRLFMCHDYLPGGRDMQYVTTVAEQRASNIHIHQGIDEDSFVAMREARDKTLEMPVLILPSVQVNMRSGQLPPPEANGVSYLKIPLNKL 4ysl B 1.46 BS02 GSH B 1 D78 H149 D170 F173 A180 R181 Y214 P260 V261 D78 H149 D170 F173 A180 R181 Y214 P260 V261 A5VWI3 MIIGNNLHVDAFYDEATSTISYLVMDRETRQCALIDSVLDYDPKSGRTCSASADRLVERVNELNASVRWVLETHVHADHLSAAAYLKEKLGGHTAIGAHITQVQKVFGALFNAEPGFARDGSQFDVLLEDEEGFRIGNLQARALHTPGHTPACMSFMIEDAGEIAVFVGDTLFMPDYGTARCDFPGADARTLYRSIRRLLAFPDQTRLFMCHDYLPGGRDMQYVTTVAEQRASNIHIHQGIDEDSFVAMREARDKTLEMPVLILPSVQVNMRSGQLPPPEANGVSYLKIPLNKL 4z3w A 2.21 BS01 SF4 A 1 N76 R77 R181 G247 S248 S298 C299 C302 M304 K305 C306 C534 N76 R77 R181 G247 S248 S298 C299 C302 M304 K305 C306 C534 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSA 4z3w A 2.21 BS02 MG A 1 M94 S183 M94 S183 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSA 4z3w A 2.21 BS03 4KX A 1 P249 E251 W259 H260 N263 F264 C322 F323 L434 L436 L438 S439 M440 N442 Y445 I457 T458 E461 Q466 P499 R500 S504 M505 P249 E251 W259 H260 N263 F264 C322 F323 L434 L436 L438 S439 M440 N442 Y445 I457 T458 E461 Q466 P499 R500 S504 M505 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSA 4z3w B 2.21 BS03 4KX B 1 P249 W259 H260 N263 F264 R272 C322 F323 L434 L436 L438 S439 M440 N442 Y445 T458 E461 Q466 R500 S504 M505 P249 W259 H260 N263 F264 R272 C322 F323 L434 L436 L438 S439 M440 N442 Y445 T458 E461 Q466 R500 S504 M505 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSA 4z3w C 2.21 BS03 4KX C 1 I242 L243 P249 E251 W259 H260 N263 F264 C322 F323 L434 L436 L438 S439 M440 N442 Y445 T458 E461 Q466 P499 R500 G501 S504 M505 N602 I242 L243 P249 E251 W259 H260 N263 F264 C322 F323 L434 L436 L438 S439 M440 N442 Y445 T458 E461 Q466 P499 R500 G501 S504 M505 N602 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSAG 4z3w D 2.21 BS03 4KX D 1 I242 P249 W259 H260 N263 F264 C322 F323 L434 L436 L438 S439 M440 Y445 I457 T458 E461 Q466 P499 R500 S504 M505 K601 N602 I242 P249 W259 H260 N263 F264 C322 F323 L434 L436 L438 S439 M440 Y445 I457 T458 E461 Q466 P499 R500 S504 M505 K601 N602 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSA 4z3w E 2.21 BS01 SF4 E 1 C20 N21 G22 C23 R24 A25 C26 V51 P62 C128 V130 L133 C14 N15 G16 C17 R18 A19 C20 V45 P56 C122 V124 L127 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPRTEMEIGLESLISRFGADVVADTVEQ 4z3w E 2.21 BS02 SF4 E 2 C30 H34 R48 V49 Y64 C113 D114 L115 C116 P122 L123 C124 C24 H28 R42 V43 Y58 C107 D108 L109 C110 P116 L117 C118 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPRTEMEIGLESLISRFGADVVADTVEQ 4z3w E 2.21 BS03 SF4 E 3 C73 R76 C89 C92 A94 C96 S98 R99 C67 R70 C83 C86 A88 C90 S92 R93 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPRTEMEIGLESLISRFGADVVADTVEQ 4z3w E 2.21 BS04 SF4 F 1 E67 R93 E61 R87 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPRTEMEIGLESLISRFGADVVADTVEQ 4z3w F 2.21 BS02 SF4 F 3 C30 H34 R48 V49 Y64 C113 L115 C116 P122 C124 C24 H28 R42 V43 Y58 C107 L109 C110 P116 C118 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPDESVKRTEMEIGLESLISRFGADVVADTVEQLT 4z3w F 2.21 BS03 SF4 F 1 T69 C73 C89 C92 A94 C96 S98 R99 T63 C67 C83 C86 A88 C90 S92 R93 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPDESVKRTEMEIGLESLISRFGADVVADTVEQLT 4z3w G 2.21 BS03 SF4 G 3 C73 C89 C92 A94 C96 S98 R99 C67 C83 C86 A88 C90 S92 R93 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPDESVKRTEMEIGLESLISRFGADVVADTVEQL 4z3w H 2.21 BS03 SF4 H 3 E72 C73 R76 C89 C92 A94 C96 S98 R99 E67 C68 R71 C84 C87 A89 C91 S93 R94 Q39TV9 KKRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVETEMEIGLESLISRFGADVVADTVEQ 4z3x A 1.85 BS03 4KX A 1 P249 W259 H260 N263 F264 R272 F323 L436 L438 S439 M440 Y445 T458 E461 Q466 R500 S504 M505 P249 W259 H260 N263 F264 R272 F323 L436 L438 S439 M440 Y445 T458 E461 Q466 R500 S504 M505 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSAG 4z3x B 1.85 BS03 4KX B 1 P249 W259 H260 F264 F323 L436 L438 S439 M440 Y445 T458 E461 Q466 R500 S504 M505 P249 W259 H260 F264 F323 L436 L438 S439 M440 Y445 T458 E461 Q466 R500 S504 M505 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSAG 4z3x E 1.85 BS03 SF4 E 3 C73 R76 C89 C92 C96 S98 R99 C68 R71 C84 C87 C91 S93 R94 Q39TV9 KKRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPDKRTEMEIGLESLISRFGADVVADTVEQ 4z3x F 1.85 BS01 SF4 F 2 C20 N21 G22 C23 R24 C26 P62 C128 V130 A132 L133 C14 N15 G16 C17 R18 C20 P56 C122 V124 A126 L127 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPDESVKRTEMEIGLESLISRFGADVVADTVEQLT 4z3x F 1.85 BS02 SF4 F 3 C30 H34 V49 Y64 C113 L115 C116 P122 C124 C24 H28 V43 Y58 C107 L109 C110 P116 C118 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPDESVKRTEMEIGLESLISRFGADVVADTVEQLT 4z3x F 1.85 BS03 SF4 F 1 T69 C73 R76 C89 C92 A94 C96 S98 R99 T63 C67 R70 C83 C86 A88 C90 S92 R93 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPDESVKRTEMEIGLESLISRFGADVVADTVEQLT 4z3x H 1.85 BS03 SF4 H 1 T69 E72 C73 C89 C92 C96 S98 R99 T64 E67 C68 C84 C87 C91 S93 R94 Q39TV9 KKRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVETEMEIGLESLISRFGADVVADTVEQ 4z3z A 2.67 BS01 SF4 A 1 R77 R181 G247 S248 S298 C299 C302 M304 C306 C534 G536 R77 R181 G247 S248 S298 C299 C302 M304 C306 C534 G536 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSA 4z3z A 2.67 BS02 MG A 1 M94 S183 S185 M94 S183 S185 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSA 4z3z A 2.67 BS03 ZN A 1 E251 H255 E257 H260 E251 H255 E257 H260 Q39TV8 MRYAETGYVLEVDLTKGSIERVATDPRDTELYLGGLGTNAKILWDRVPPEVEPFSPENLLIFAAGLLCGTPATGCNRTIVSTVSPQTKLMAFSMMGGFWAPELKYAGYDKIIFRGKSPELVYLYINNDKVEIRDASHLKGKGAIETAEIIKKELNEPRAQVAAIGKAGENRVFYASIEQGRSSASRGGIGAVMGDKGLKAVVVRGTKDLCVAKPEEYIGLCNEVLDYIKHREENPIPDVMPILAGLGSPQEMKVHDEKWHTENFNWGNARTRRKDFWTDEVSHAWEKTMDKARTRLISCYNCPMKCGATISMEGLPTYMMKCFTKLTYTMAAYSDLDFGLRIAQKATEYGLDGFSAPQVMAFAFELLEKGILKDSDFPGLPEGNEERFFYLLDKIVNRDGIGDILANGTYWAAQEIGNGAEDYAHNNIKKHEQLPLKLSMLNPIYYLMYCTGEKINITQIEGQFPQAPYPKLEQREAFVEDWIQVPDEKFKKIFLEWEPRGEKSMPNFPTVDMCCDIVDWQEMMHYIDDALGQCAGLSSFPLKPPYHIHNYPKFIAAGAGIEMDTEKLKKAAKRYRTLVRAFNIRRGMRRVDEQPPANHWKNRFPELEKELLDSYYKLKGWNDDGIPTKETLDDLGLGYVGDEFIKRGILSA 4z3z F 2.67 BS03 SF4 F 3 E72 C73 R76 D77 C89 C92 A94 C96 S98 R99 E66 C67 R70 D71 C83 C86 A88 C90 S92 R93 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPDESVKRTEMEIGLESLISRFGADVVADTVEQLT 4z3z G 2.67 BS03 SF4 G 3 C73 D77 C89 C92 A94 C96 S98 R99 C67 D71 C83 C86 A88 C90 S92 R93 Q39TV9 KRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVEEPDESVKRTEMEIGLESLISRFGADVVADTVEQL 4z3z H 2.67 BS03 SF4 H 3 E72 C73 D77 C89 C92 C96 S98 R99 E67 C68 D72 C84 C87 C91 S93 R94 Q39TV9 KKRIVKTINIDADKCNGCRACEVICSAFHAMPPYSSNNPARSRVRVVRDPLRDIYVPLYAGEYTESECIGRDKFIIDGKEYDECGFCRASCPSRDLFREPDSGLPLKCDLCDGEPEPLCVKWCLVGALSVTEREVETEMEIGLESLISRFGADVVADTVEQ 4z76 A 1.88 BS01 III C 1 Y7 F22 Q63 R66 S69 D70 W73 V76 S77 T80 Y84 F95 R97 F99 T143 K146 W147 A150 D152 Y155 Y156 Y159 E163 W167 Y171 Y8 F23 Q64 R67 S70 D71 W74 V77 S78 T81 Y85 F96 R98 F100 T144 K147 W148 A151 D153 Y156 Y157 Y160 E164 W168 Y172 P01902 MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRWKP 4z76 D 1.88 BS01 III F 1 Y7 V9 Q63 R66 S69 D70 W73 S77 T80 Y84 F95 R97 F99 T143 K146 W147 A150 D152 Y155 Y156 Y159 W167 Y171 Y8 V10 Q64 R67 S70 D71 W74 S78 T81 Y85 F96 R98 F100 T144 K147 W148 A151 D153 Y156 Y157 Y160 W168 Y172 P01902 MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRWKP 4z77 A 1.85 BS01 III C 1 Y7 V9 F22 F45 Y59 Q63 R66 S69 D70 W73 V76 S77 T80 Y84 R97 F99 H114 F116 Y123 T143 K146 W147 A150 D152 Y155 Y156 Y159 E163 W167 Y8 V10 F23 F46 Y60 Q64 R67 S70 D71 W74 V77 S78 T81 Y85 R98 F100 H115 F117 Y124 T144 K147 W148 A151 D153 Y156 Y157 Y160 E164 W168 P01902 MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRWKP 4z77 D 1.85 BS01 III F 1 Y7 V9 F22 F45 Q63 R66 D70 W73 V76 S77 T80 Y84 R97 F99 T143 K146 W147 D152 Y155 Y156 Y159 W167 Y171 Y8 V10 F23 F46 Q64 R67 D71 W74 V77 S78 T81 Y85 R98 F100 T144 K147 W148 D153 Y156 Y157 Y160 W168 Y172 P01902 MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRWKP 4z78 A 2.30 BS01 III C 1 Y7 V9 Q63 R66 S69 D70 W73 Y84 R97 F99 H114 Y123 T143 K146 W147 D152 Y155 Y156 Y159 E163 W167 Y171 Y8 V10 Q64 R67 S70 D71 W74 Y85 R98 F100 H115 Y124 T144 K147 W148 D153 Y156 Y157 Y160 E164 W168 Y172 P01902 MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRWKP 4z78 D 2.30 BS01 III F 1 Y7 V9 A24 Q63 R66 S69 D70 W73 S77 T80 R97 F99 Y123 I142 T143 K146 W147 A150 D152 Y155 Y156 Y159 E163 W167 Y171 Y8 V10 A25 Q64 R67 S70 D71 W74 S78 T81 R98 F100 Y124 I143 T144 K147 W148 A151 D153 Y156 Y157 Y160 E164 W168 Y172 P01902 MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRWKP 4z78 G 2.30 BS01 III I 1 Y7 V9 Q63 R66 S69 D70 W73 V76 S77 T80 R83 Y84 R97 F99 T143 K146 W147 Y155 Y156 Y159 E163 W167 Y171 Y8 V10 Q64 R67 S70 D71 W74 V77 S78 T81 R84 Y85 R98 F100 T144 K147 W148 Y156 Y157 Y160 E164 W168 Y172 P01902 MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPLGKEQNYTCHVHHKGLPEPLTLRWKP 4z8f H 1.75 BS01 NUC E 1 R50 R52 S52C N53 R96 P99 R50 R52 S55 N56 R102 P105 EVQLVESGGGLVQPKGSLKLSCAASGFTFNTYAMNWVRQAPGKGLEWVARIRSKSNNYATYYADSVKDRFTISRDDSQSMLYLQMNNLKTEDTAMYYCVRHRGAPLYYGNGAWFAYWGQGTLVTVSAAKTTPPSVYPLAPGCGDTTGSSVTSGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSETVTCSVAHPASSTTVDKKLEP 4z8f H 1.75 BS02 NUC A 1 V2 G26 F27 T28 Y32 R94 Y100B Y102 V2 G26 F27 T28 Y32 R100 Y108 Y116 EVQLVESGGGLVQPKGSLKLSCAASGFTFNTYAMNWVRQAPGKGLEWVARIRSKSNNYATYYADSVKDRFTISRDDSQSMLYLQMNNLKTEDTAMYYCVRHRGAPLYYGNGAWFAYWGQGTLVTVSAAKTTPPSVYPLAPGCGDTTGSSVTSGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSETVTCSVAHPASSTTVDKKLEP 4zfp A 1.96 BS01 AU A 1 W28 A31 M105 W108 W28 A31 M105 W108 3.2.1.17 P00698 26054833 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4zji A 1.99 BS01 4OQ A 1 E315 V318 M319 N322 I327 V328 M344 F379 L380 N383 V385 H387 L405 T406 D407 A412 E57 V60 M61 N64 I69 V70 M86 F121 L122 N125 V127 H129 L147 T148 D149 A154 2.7.11.1 Q13153 LEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATK 4zjj A 2.20 BS01 4OR A 1 M301 I312 E315 V318 M319 N322 I327 V328 V342 M344 F379 L380 N383 H387 L405 T406 D407 A412 M53 I60 E63 V66 M67 N70 I75 V76 V90 M92 F127 L128 N131 H135 L153 T154 D155 A160 2.7.11.1 Q13153 SDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKE 4zjj B 2.20 BS01 4OR B 1 M301 I312 E315 M319 N322 I327 V328 V342 F379 L380 N383 H387 L405 T406 D407 M51 I57 E60 M64 N67 I72 V73 V87 F124 L125 N128 H132 L150 T151 D152 2.7.11.1 Q13153 EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKE 4zjj C 2.20 BS01 4OR C 1 E315 V318 M319 N322 I327 V328 V342 M344 F379 L380 N383 H387 L405 T406 D407 E60 V63 M64 N67 I72 V73 V85 M87 F122 L123 N126 H130 L148 T149 D150 2.7.11.1 Q13153 EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVAQEVAIKQMNLQKKELIINEILVMRENKNPNIVNYLDSYLVELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGEQSKRSTMVGTPYWMAPEVVTAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATK 4zjj D 2.20 BS01 4OR D 1 M301 E315 V318 M319 N322 I327 V328 V342 M344 F379 L380 N383 H387 L405 T406 D407 F410 M43 E54 V57 M58 N61 I66 V67 V79 M81 F116 L117 N120 H124 L142 T143 D144 F147 2.7.11.1 Q13153 EILEKLRSIVSVKKKYTRFEKIGQGASGTVYTAMDVEVAIKQMNLPKKELIINEILVMRENKNPNIVNYLDSYGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT 4zjj D 2.20 BS02 MG D 1 E461 P462 E194 P195 2.7.11.1 Q13153 EILEKLRSIVSVKKKYTRFEKIGQGASGTVYTAMDVEVAIKQMNLPKKELIINEILVMRENKNPNIVNYLDSYGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT 4zrt A 1.74 BS01 III B 1 R24 R45 Y46 R47 D48 V49 F182 S215 S216 A217 G218 I219 G220 R221 Q262 R23 R44 Y45 R46 D47 V48 F181 S214 S215 A216 G217 I218 G219 R220 Q261 3.1.3.48 P18031 24359314 EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHSSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED 4zxg A 1.70 BS01 MES A 1 Y25 L26 L196 P197 N198 Y23 L24 L191 P192 N193 2.5.1.18 Q8MU52 26072058 DNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDTPFEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNLFKQNETTFLNEDLPKWSGYFEKLLKKNHTNNNKYYFVGNNLTYADLAVFNLYDDIETKYPSLKNFPLLKAHNEFISNLPNIKNYITNR 5a1p A 2.50 BS01 HEM A 1 R105 I118 S119 W126 R130 F137 A305 G306 V313 A370 L373 R375 P434 F435 G436 S437 R440 N441 C442 I443 G444 A448 M452 R80 I93 S94 W101 R105 F112 A273 G274 V281 A338 L341 R343 P402 F403 G404 S405 R408 N409 C410 I411 G412 A416 M420 1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.9 P08684 26066995 GTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTRVDFLQLMIDSQNSSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 5a1p A 2.50 BS02 STR A 1 F213 D214 D217 F219 F220 F188 D189 D192 F194 F195 1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.9 P08684 26066995 GTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTRVDFLQLMIDSQNSSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 5a1p A 2.50 BS03 CIT A 1 T27 H28 S29 H30 F46 Q78 T2 H3 S4 H5 F21 Q53 1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.9 P08684 26066995 GTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTRVDFLQLMIDSQNSSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 5a1r A 2.45 BS02 HEM A 1 R105 I118 S119 W126 R130 A305 G306 T309 V313 I369 A370 L373 R375 P434 F435 G436 S437 R440 N441 C442 I443 G444 A448 M452 R80 I93 S94 W101 R105 A270 G271 T274 V278 I334 A335 L338 R340 P399 F400 G401 S402 R405 N406 C407 I408 G409 A413 M417 1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.9 P08684 26066995 GTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLERVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 5a39 A 2.80 BS01 ZN A 1 C103 C106 C125 C128 C4 C7 C26 C29 P28519 APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHR 5a39 B 2.80 BS01 NUC C 1 T151 P153 F174 R206 T52 P54 F75 R107 P28519 APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRR 5a39 B 2.80 BS02 NUC D 1 T140 K141 T142 D152 N168 P169 H170 A175 R176 M177 Q178 T41 K42 T43 D53 N69 P70 H71 A76 R77 M78 Q79 P28519 APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRR 5a39 B 2.80 BS03 NUC E 1 T140 K141 T142 N168 H170 A175 R176 M177 Q178 T41 K42 T43 N69 H71 A76 R77 M78 Q79 P28519 APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRR 5a39 B 2.80 BS04 NUC F 1 P153 F174 R206 P54 F75 R107 P28519 APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRR 5aun A 1.63 BS01 ZN A 1 C73 C76 C110 C113 C73 C76 C110 C113 Q5JIH3 26056269 MHEWALADAIVRTVLDYAQREGASRVKAVRVVLGELQDVAEDIVKFAMEQLFAGTIAEGAEIEFVEEEAVFKCRNCNYEWKLKEVKDKFDERIKEDIHFIPEVVHAFLACPKCGSHDFEVVKGRGVYVAGIKIEKE 5aun B 1.63 BS01 ADP B 1 G30 V31 G32 K33 S34 L35 N187 M188 P217 F218 Y219 L222 F237 G30 V31 G32 K33 S34 L35 N187 M188 P209 F210 Y211 L214 F229 Q5JIH4 26056269 MNAIDPREIAINARLEGVKRIIPVVSGKGGVGKSLVSTTLALVLAEKGYRVGLLDLDFHGASDHVILGFEPKEFPEEDRGVVPPTVHGIKFMTIAYYTEDRPTPLRGKEISDALIELLTITRWDELDYLVIDMPPGLGDQLLDVLRFLKRGEFLVVATPSKLSLNVVRKLIELLKEEGHKVIGVVENMKLKDVEKLAEEFGVPYLVGIPFYPDLDAKVGNVEELMKTEFAGKVRELAGRL 5auo B 1.80 BS01 ACP B 1 G29 G30 V31 G32 K33 S34 L35 D57 P135 N187 M188 P217 F218 Y219 L222 G26 G27 V28 G29 K30 S31 L32 D54 P132 N184 M185 P206 F207 Y208 L211 Q5JIH4 26056269 IDPREIAINARLEGVKRIIPVVSGKGGVGKSLVSTTLALVLAEKGYRVGLLDLDFHGASDHVILGFEPKEFPEEDRGVVPPTVHGIKFMTIAYYTEDRPTPLRGKEISDALIELLTITRWDELDYLVIDMPPGLGDQLLDVLRFLKRGEFLVVATPSKLSLNVVRKLIELLKEEGHKVIGVVENMKLKDVEKLAEEFGVPYLVGIPFYPDLDAKVGNVEELMKTEFAGKVRELAGRL 5aup B 3.10 BS01 ACP B 1 G30 G32 K33 S34 L35 D57 P135 N187 M188 I216 P217 Y219 L222 D223 F237 G30 G32 K33 S34 L35 D57 P135 N187 M188 I208 P209 Y211 L214 D215 F229 Q5JIH4 26056269 MNAIDPREIAINARLEGVKRIIPVVSGKGGVGKSLVSTTLALVLAEKGYRVGLLDLDFHGASDHVILGFEPKEFPEEDRGVVPPTVHGIKFMTIAYYTEDRPTPLRGKEISDALIELLTITRWDELDYLVIDMPPGLGDQLLDVLRFLKRGEFLVVATPSKLSLNVVRKLIELLKEEGHKVIGVVENMKLKDVEKLAEEFGVPYLVGIPFYPDLDAKVGNVEELMKTEFAGKVRELAGRL 5aup B 3.10 BS02 ACP I 1 K28 G29 S160 L162 K28 G29 S160 L162 Q5JIH4 26056269 MNAIDPREIAINARLEGVKRIIPVVSGKGGVGKSLVSTTLALVLAEKGYRVGLLDLDFHGASDHVILGFEPKEFPEEDRGVVPPTVHGIKFMTIAYYTEDRPTPLRGKEISDALIELLTITRWDELDYLVIDMPPGLGDQLLDVLRFLKRGEFLVVATPSKLSLNVVRKLIELLKEEGHKVIGVVENMKLKDVEKLAEEFGVPYLVGIPFYPDLDAKVGNVEELMKTEFAGKVRELAGRL 5aup I 3.10 BS02 ACP I 1 G29 G30 G32 K33 S34 L35 D57 P135 N187 M188 P217 F218 Y219 L222 D223 G29 G30 G32 K33 S34 L35 D57 P135 N187 M188 P210 F211 Y212 L215 D216 Q5JIH4 26056269 MNAIDPREIAINARLEGVKRIIPVVSGKGGVGKSLVSTTLALVLAEKGYRVGLLDLDFHGASDHVILGFEPKEFPEEDRGVVPPTVHGIKFMTIAYYTEDRPTPLRGKEISDALIELLTITRWDELDYLVIDMPPGLGDQLLDVLRFLKRGEFLVVATPSKLSLNVVRKLIELLKEEGHKVIGVVENMKLRKDVEKLAEEFGVPYLVGIPFYPDLDAKVGNVEELMKTEFAGKVRELAGRL 5aup I 3.10 BS03 MG I 1 S34 D57 S34 D57 Q5JIH4 26056269 MNAIDPREIAINARLEGVKRIIPVVSGKGGVGKSLVSTTLALVLAEKGYRVGLLDLDFHGASDHVILGFEPKEFPEEDRGVVPPTVHGIKFMTIAYYTEDRPTPLRGKEISDALIELLTITRWDELDYLVIDMPPGLGDQLLDVLRFLKRGEFLVVATPSKLSLNVVRKLIELLKEEGHKVIGVVENMKLRKDVEKLAEEFGVPYLVGIPFYPDLDAKVGNVEELMKTEFAGKVRELAGRL 5bqx A 2.00 BS01 4UR A 1 S162 Y163 G166 Y167 R238 V239 Y240 S241 E260 T263 P264 S11 Y12 G15 Y16 R84 V85 Y86 S87 E106 T109 P110 Q86WV6 NFNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDRAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPSFSLSQEVLRHLRQE 5bru A 1.60 BS02 8TH A 1 H94 H96 H119 V121 F130 M197 T198 T199 P201 W208 H92 H94 H117 V119 F128 M195 T196 T197 P199 W206 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGMAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSMTTPPLLESVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKLRQIKASFK 5brx C 2.05 BS01 TI4 D 1 W55 V108 I118 W57 V110 I120 Q8WSF8 DDKLHSQANLMRLKSDLFNRSYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYWEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER 5bu5 B 1.95 BS01 CA A 1 K62 N63 Q66 K3 N4 Q7 Q9AYZ3 QVKNDEQDVELADHDARIAANTKAINILEVRLTTAEGKIVVLRSDVDYLLDEVIDIQAHLVTVDQRLDGVESDVSDIKSDYVSKTVTESQSLASPLDVKTSYSVDGIQVVGARQTGWTAATGTPLLGSFNANQSYTVGTTYTQSEVAALATGLEQARQRILALETALRLHGLID 5bv2 P 1.53 BS01 HDD P 1 R125 I126 V127 H128 R165 S167 G184 F185 A186 V199 G200 N201 F206 A211 F214 G273 I274 H275 F391 L407 G410 R411 S414 Y415 T418 Q419 R422 R119 I120 V121 H122 R159 S161 G178 F179 A180 V193 G194 N195 F200 A205 F208 G267 I268 H269 F385 L401 G404 R405 S408 Y409 T412 Q413 R416 1.11.1.6 P21179 KNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTPPGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGDRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINASGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGNMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGISLTDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALKAKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDANYYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIVEADSADGSFMDELLTLMAAHRVWSRIPKIDSIPA 5bv2 P 1.53 BS02 HDD S 1 I114 F117 D118 I108 F111 D112 1.11.1.6 P21179 KNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTPPGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGDRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINASGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGNMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGISLTDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALKAKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDANYYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIVEADSADGSFMDELLTLMAAHRVWSRIPKIDSIPA 5bw2 A 2.27 BS02 4VU B 1 W55 V108 M116 I118 W57 V110 M118 I120 Q8WSF8 DKLHSQANLMRLKSDLFNRSMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYWEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRA 5bw2 B 2.27 BS02 4VU C 1 W55 I118 W49 I112 Q8WSF8 SQANLMRLKSDLFYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYWEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRA 5bwm A 2.50 BS01 GDP A 1 A15 C16 G17 K18 T19 C20 F30 K118 D120 L121 S160 A161 K162 A13 C14 G15 K16 T17 C18 F28 K116 D118 L119 S158 A159 K160 P61586 26067270 AIRKKLVIVGDGACGKTCLLIVNSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL 5bwm A 2.50 BS03 NAI B 1 E40 N41 E38 N39 P61586 26067270 AIRKKLVIVGDGACGKTCLLIVNSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL 5bwm B 2.50 BS01 NAI B 1 A51 N55 R59 R97 G98 D99 D100 W102 I103 E137 S142 T143 Y151 R155 E185 A37 N41 R45 R83 G84 D85 D86 W88 I89 E123 S128 T129 Y137 R141 E171 Q8KNY0 26067270 KYKLCTNKEEADAWGKKQFNKWSKEEKSAIRDYTKNARPYNEFLRMHAGKLDSDPTMKKKIESLDKALNRKEAKVNDNIKVYRGDDAWIFGKEYDNSIIKNGKVDREKFKEIQKKFQGKTTTEFGYISTSILIDAGYAKTRPVMTEFKVGSGTHGAYMNSDDLTAYPGQYELLLPRNTVYKIEKIYIAIDNNTQKEQIKVEATIK 5bxi A 1.70 BS01 BCT A 1 K14 T96 N117 V119 H120 K12 T94 N115 V117 H118 2.7.4.6 S8FF85 AKQQERTYIMVKPDGVQRGLVSEVIRRFEQRGYKLVALKMKSPDATLLEEHYADLKGKPFFPGLISYMTSGPVVCMVWEGTDVVKQGRRMLGETRPLESNPGTLRGDFCIDVGRNIVHGSDSVESANKEISLWFTPEEICEWTSAQHKWVYE 5bxi B 1.70 BS01 BCT B 1 Q6 R8 Q4 R6 2.7.4.6 S8FF85 AKQQERTYIMVKPDGVQRGLVSEVIRRFEQRGYKLVALKMKSPDATLLEEHYADLKGKPFFPGLISYMTSGPVVCMVWEGTDVVKQGRRMLGETRPLESNPGTLRGDFCIDVGRNIVHGSDSVESANKEISLWFTPEEICEWTSAQHKWVYEQ 5bxi D 1.70 BS01 BCT D 1 K14 T96 N117 H120 K12 T94 N115 H118 2.7.4.6 S8FF85 AKQQERTYIMVKPDGVQRGLVSEVIRRFEQRGYKLVALKMKSPDATLLEEHYADLKGKPFFPGLISYMTSGPVVCMVWEGTDVVKQGRRMLGETRPLESNPGTLRGDFCIDVGRNIVHGSDSVESANKEISLWFTPEEICEWTSAQHKWVYEQGENLY 5byu A 2.40 BS01 COA A 1 V57 V58 I59 S87 S88 K108 V110 I112 N117 S119 V55 V56 I57 S85 S86 K106 V108 I110 N115 S117 Q5ZRL4 EINKIIHKKTFDIAWGDMDALGHVNNARYFDYFQEARIDWLRELDIKMTGQTGPVVIHVACTFLKPIVYPATVTIHSKVNSLGNSSMIMDHDLYQEETLMAQGVSKIVWIDYTQNKSVPLPDIIRNLV 5byu A 2.40 BS02 COA B 1 H25 V26 N28 Y31 F65 L66 P68 H23 V24 N26 Y29 F63 L64 P66 Q5ZRL4 EINKIIHKKTFDIAWGDMDALGHVNNARYFDYFQEARIDWLRELDIKMTGQTGPVVIHVACTFLKPIVYPATVTIHSKVNSLGNSSMIMDHDLYQEETLMAQGVSKIVWIDYTQNKSVPLPDIIRNLV 5byu B 2.40 BS01 COA A 1 H25 N28 T64 F65 L66 K67 P68 H23 N26 T62 F63 L64 K65 P66 Q5ZRL4 EINKIIHKKTFDIAWGDMDALGHVNNARYFDYFQEARIDWLRELDIKMTGQTGPVVIHVACTFLKPIVYPATVTIHSKVNSLGNSSMIMDHDLYQEETLMAQGVSKIVWIDYTQNKSVPLPDIIRNLV 5byu B 2.40 BS02 COA B 1 V57 V58 I59 G85 N86 S87 S88 K108 V110 I112 V55 V56 I57 G83 N84 S85 S86 K106 V108 I110 Q5ZRL4 EINKIIHKKTFDIAWGDMDALGHVNNARYFDYFQEARIDWLRELDIKMTGQTGPVVIHVACTFLKPIVYPATVTIHSKVNSLGNSSMIMDHDLYQEETLMAQGVSKIVWIDYTQNKSVPLPDIIRNLV 5byu G 2.40 BS01 COA G 1 V57 V58 I59 G85 N86 S87 S88 K108 V110 I112 N117 S119 V54 V55 I56 G82 N83 S84 S85 K105 V107 I109 N114 S116 Q5ZRL4 INKIIHKKTFDIAWGDMDALGHVNNARYFDYFQEARIDWLRELDIKMTGQTGPVVIHVACTFLKPIVYPATVTIHSKVNSLGNSSMIMDHDLYQEETLMAQGVSKIVWIDYTQNKSVPLPDIIRNLV 5byu G 2.40 BS02 COA G 2 V26 Y31 T64 F65 L66 P68 V23 Y28 T61 F62 L63 P65 Q5ZRL4 INKIIHKKTFDIAWGDMDALGHVNNARYFDYFQEARIDWLRELDIKMTGQTGPVVIHVACTFLKPIVYPATVTIHSKVNSLGNSSMIMDHDLYQEETLMAQGVSKIVWIDYTQNKSVPLPDIIRNLV 5byu H 2.40 BS02 COA G 3 V57 V58 I59 S88 V55 V56 I57 S86 Q5ZRL4 EINKIIHKKTFDIAWGDMDALGHVNNARYFDYFQEARIDWLRELDIKMTGQTGPVVIHVACTFLKPIVYPATVTIHSKVNSLGNSSMIMDHDLYQEETLMAQGVSKIVWIDYTQNKSVPLPDIIRNLV