3wzd A 1.57 BS01 LEV A 1 L840 G841 A866 K868 E885 I888 L889 V899 V916 E917 F918 C919 K920 G922 L1035 C1045 D1046 F1047 L1049 L21 G22 A43 K45 E62 I65 L66 V76 V93 E94 F95 C96 K97 G99 L162 C172 D173 F174 L176 2.7.10.1 P35968 25589937 LPYDASKWEFPRDRLKLGKPLGGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLALPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQAN 3wze A 1.90 BS01 BAX A 1 L840 V848 A866 E885 L889 I892 V898 V899 V916 E917 F918 C919 K920 G922 H1026 L1035 I1044 C1045 D1046 F1047 L26 V34 A52 E71 L75 I78 V84 V85 V102 E103 F104 C105 K106 G108 H158 L167 I176 C177 D178 F179 2.7.10.1 P35968 25589937 EHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQAN 4cuk A 2.18 BS01 NAI A 1 Y100 V105 I150 G151 T152 G153 K154 I155 F173 D174 P175 Y176 H204 C205 P206 N211 T232 S233 D258 Y260 H295 A297 Y100 V105 I150 G151 T152 G153 K154 I155 F173 D174 P175 Y176 H204 C205 P206 N211 T232 S233 D258 Y260 H295 A297 1.1.1.28 Q8Z780 MKLAVYSTKQYDKKYLQQVNEAFGFELEFFDFLLTEKTAKTANGCEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLQVVRVPAYSPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMHGKTAGVIGTGKIGVAALRILKGFGMRLLAFDPYPSTAALDLGVEYVDLQTLFAESDVISLHCPLTPENYHLLNHAAFDQMKNGVMIINTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSVDVIQDDVFRRLSACHNVLFTGHQAFLTAEALISISETTLQNLSQLEKGEACPNALFK 4cuk D 2.18 BS01 NAI D 1 Y100 V105 G151 T152 G153 K154 I155 F173 D174 P175 Y176 H204 C205 P206 N211 T232 S233 D258 Y260 H295 A297 Y100 V105 G151 T152 G153 K154 I155 F173 D174 P175 Y176 H204 C205 P206 N211 T232 S233 D258 Y260 H295 A297 1.1.1.28 Q8Z780 MKLAVYSTKQYDKKYLQQVNEAFGFELEFFDFLLTEKTAKTANGCEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLQVVRVPAYSPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMHGKTAGVIGTGKIGVAALRILKGFGMRLLAFDPYPSTAALDLGVEYVDLQTLFAESDVISLHCPLTPENYHLLNHAAFDQMKNGVMIINTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSVDVIQDDVFRRLSACHNVLFTGHQAFLTAEALISISETTLQNLSQLEKGEACPNALFK 4p62 A 1.89 BS01 ZN A 1 H104 H106 H182 H78 H80 H156 B5DCA0 ASRGCADDAGWNDPAMPQKVYGNTWYVGTCGISALLVTSDAGHILVDAATPQAGPQILANIRALGFRPEDVRAIVLSHEHFDHAGSLAELQKATGAPVYARAPAIDTLKRGLPDRTDPQFEVAEPVAPVANIVTLADDGVVSVGPLALTAVASPGHTPGGTSWTWRSCEGDDCRQMVYADSLTAISDDVYRYSDDAAHPGYLAAFRNTLARVAALDCDILVTPHPSASGLWNRIGPRAAAPLMDTTACRRYAQGARQRLEKRLAEEAAA 4p62 A 1.89 BS02 ZN A 2 D108 H109 H250 D82 H83 H224 B5DCA0 ASRGCADDAGWNDPAMPQKVYGNTWYVGTCGISALLVTSDAGHILVDAATPQAGPQILANIRALGFRPEDVRAIVLSHEHFDHAGSLAELQKATGAPVYARAPAIDTLKRGLPDRTDPQFEVAEPVAPVANIVTLADDGVVSVGPLALTAVASPGHTPGGTSWTWRSCEGDDCRQMVYADSLTAISDDVYRYSDDAAHPGYLAAFRNTLARVAALDCDILVTPHPSASGLWNRIGPRAAAPLMDTTACRRYAQGARQRLEKRLAEEAAA 4p62 A 1.89 BS03 ZN A 3 D242 D244 D216 D218 B5DCA0 ASRGCADDAGWNDPAMPQKVYGNTWYVGTCGISALLVTSDAGHILVDAATPQAGPQILANIRALGFRPEDVRAIVLSHEHFDHAGSLAELQKATGAPVYARAPAIDTLKRGLPDRTDPQFEVAEPVAPVANIVTLADDGVVSVGPLALTAVASPGHTPGGTSWTWRSCEGDDCRQMVYADSLTAISDDVYRYSDDAAHPGYLAAFRNTLARVAALDCDILVTPHPSASGLWNRIGPRAAAPLMDTTACRRYAQGARQRLEKRLAEEAAA 4plp A 1.49 BS01 NAD A 1 I17 G20 S21 I22 D45 P46 S47 V66 L91 S92 V93 T95 T114 V115 E117 G160 A161 N162 P163 W229 S230 G233 I350 V400 I15 G18 S19 I20 D43 P44 S45 V64 L89 S90 V91 T93 T112 V113 E115 G158 A159 N160 P161 W227 S228 G231 I348 V398 2.5.1.44 O32323 DWPVYHRIDGPIVMIGFGSIGRGTLPLIERHFAFDRSKLVVIDPSDEARKLAEARGVRFIQQAVTRDNYRELLVPLLTAGPGQGFCVNLSVDTSSLDIMELARENGALYIDTVVEPWLGFYFDPDLKPEARSNYALRETVLAARRNKPGGTTAVSCCGANPGMVSWFVKQALVNLAADLGVTGEEPTTREEWARLAMDLGVKGIHIAERDTQRASFPKPFDVFVNTWSVEGFVSEGLQPAELGWGTFERWMPDNARGHDSGCGAGIYLLQPGANTRVRSWTPTAMAQYGFLVTHNESISIADFLTVRDAAGQAVYRPTCHYAYHPCNDAVLSLHEMFGSGKRQSDWRILDETEIVDGIDELGVLLYGHGKNAYWYGSQLSIEETRRIAPDQNATGLQVSSAVLAGMVWALENPNAGIVEADDLDFRRCLEVQTPYLGPVVGVYTDWTPLAGRPGLFPEDIDTSDPWQFRNVLVRD 4plp B 1.49 BS01 NAD B 1 I17 G20 S21 I22 D45 P46 S47 A65 V66 L91 S92 V93 T95 T114 V115 E117 G160 A161 N162 P163 W229 S230 G233 I350 V400 I15 G18 S19 I20 D43 P44 S45 A63 V64 L89 S90 V91 T93 T112 V113 E115 G158 A159 N160 P161 W227 S228 G231 I348 V398 2.5.1.44 O32323 DWPVYHRIDGPIVMIGFGSIGRGTLPLIERHFAFDRSKLVVIDPSDEARKLAEARGVRFIQQAVTRDNYRELLVPLLTAGPGQGFCVNLSVDTSSLDIMELARENGALYIDTVVEPWLGFYFDPDLKPEARSNYALRETVLAARRNKPGGTTAVSCCGANPGMVSWFVKQALVNLAADLGVTGEEPTTREEWARLAMDLGVKGIHIAERDTQRASFPKPFDVFVNTWSVEGFVSEGLQPAELGWGTFERWMPDNARGHDSGCGAGIYLLQPGANTRVRSWTPTAMAQYGFLVTHNESISIADFLTVRDAAGQAVYRPTCHYAYHPCNDAVLSLHEMFGSGKRQSDWRILDETEIVDGIDELGVLLYGHGKNAYWYGSQLSIEETRRIAPDQNATGLQVSSAVLAGMVWALENPNAGIVEADDLDFRRCLEVQTPYLGPVVGVYTDWTPLAGRPGLFPEDIDTSDPWQFRNVLVRD 4pnf A 2.11 BS01 GSH A 1 S12 P14 Q41 H53 T54 V55 P56 D67 S68 H69 F108 R113 S11 P13 Q40 H52 T53 V54 P55 D66 S67 H68 F107 R112 Q7JZM3 VKLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFTFE 4pnf B 2.11 BS01 GSH B 1 S12 P14 Q41 H53 T54 V55 P56 D67 S68 H69 F108 R113 S11 P13 Q40 H52 T53 V54 P55 D66 S67 H68 F107 R112 Q7JZM3 VKLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFTFEA 4pnf C 2.11 BS01 GSH C 1 S12 P14 I36 Q41 H53 T54 V55 P56 D67 S68 H69 F108 R113 S10 P12 I34 Q39 H51 T52 V53 P54 D65 S66 H67 F106 R111 Q7JZM3 KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFTFE 4pnf D 2.11 BS01 GSH D 1 S12 P14 I36 Q41 H53 T54 V55 P56 D67 S68 H69 F108 R113 S10 P12 I34 Q39 H51 T52 V53 P54 D65 S66 H67 F106 R111 Q7JZM3 KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFTFE 4pnf E 2.11 BS01 GSH E 1 S12 P14 Q41 H53 T54 V55 P56 D67 S68 H69 F108 R113 S10 P12 Q39 H51 T52 V53 P54 D65 S66 H67 F106 R111 Q7JZM3 KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFTFEA 4pnf F 2.11 BS01 GSH F 1 S12 P14 Q41 H53 T54 V55 D67 S68 H69 F108 R113 S10 P12 Q39 H51 T52 V53 D65 S66 H67 F106 R111 Q7JZM3 KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFTFEA 4pnf G 2.11 BS01 GSH G 1 S12 P14 I36 Q41 H53 T54 V55 P56 D67 S68 H69 F108 R113 S9 P11 I33 Q38 H50 T51 V52 P53 D64 S65 H66 F105 R110 Q7JZM3 LTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFTFEA 4pnf H 2.11 BS01 GSH H 1 S12 P14 Q41 H53 T54 V55 D67 S68 H69 F108 R113 S10 P12 Q39 H51 T52 V53 D65 S66 H67 F106 R111 Q7JZM3 KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFTFE 4png A 1.53 BS01 GSF A 1 S12 P14 T36 N41 H53 T54 V55 P56 D67 S68 H69 F108 S10 P12 T34 N39 H51 T52 V53 P54 D65 S66 H67 F106 Q8MR33 KLILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSSLEVFVKVDTTKYPRIAAWFKRLQKLPYYEEANGNGARTFESFIREYNFTFASN 4png B 1.53 BS01 GSF B 1 S12 P14 N41 H53 T54 V55 P56 D67 S68 H69 F108 R113 S12 P14 N41 H53 T54 V55 P56 D67 S68 H69 F108 R113 Q8MR33 MPKLILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSSLEVFVKVDTTKYPRIAAWFKRLQKLPYYEEANGNGARTFESFIREYNFTFASN 4q7h A 2.59 BS01 ZN A 1 H167 H206 D207 D311 H53 H92 D93 D195 3.1.5.- Q9Y3Z3 MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESPDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYQEKNPIDHVSFYCKTAPNRAIRITLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDG 4q7h A 2.59 BS02 GTP A 1 V117 I118 V133 I136 D137 Q142 R145 F165 V3 I4 V19 I22 D23 Q28 R31 F51 3.1.5.- Q9Y3Z3 MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESPDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYQEKNPIDHVSFYCKTAPNRAIRITLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDG 4q7h A 2.59 BS03 GTP B 1 Y155 V156 V378 R451 L453 F454 K455 Y41 V42 V262 R335 L337 F338 K339 3.1.5.- Q9Y3Z3 MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESPDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYQEKNPIDHVSFYCKTAPNRAIRITLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDG 4q7h B 2.59 BS01 ZN B 1 H167 H206 D207 D311 H53 H92 D93 D195 3.1.5.- Q9Y3Z3 MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESPDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMPIDHVSFYCKTAPNRAIRIKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDG 4q7h B 2.59 BS02 GTP A 1 Y155 V156 V378 R451 Y41 V42 V262 R335 3.1.5.- Q9Y3Z3 MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESPDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMPIDHVSFYCKTAPNRAIRIKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDG 4q7h B 2.59 BS03 GTP B 1 K116 V117 I118 V133 I136 D137 Q142 R145 F165 K2 V3 I4 V19 I22 D23 Q28 R31 F51 3.1.5.- Q9Y3Z3 MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESPDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMPIDHVSFYCKTAPNRAIRIKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDG 4q7h C 2.59 BS01 ZN C 1 H167 H206 D207 D311 H54 H93 D94 D194 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDDHVSFYCKTAPNRAIRIEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQD 4q7h C 2.59 BS02 GTP C 1 K116 V117 I118 I136 D137 Q142 R145 F165 K3 V4 I5 I23 D24 Q29 R32 F52 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDDHVSFYCKTAPNRAIRIEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQD 4q7h D 2.59 BS01 GTP C 1 Y155 V156 V378 R451 L453 Y41 V42 V257 R330 L332 3.1.5.- Q9Y3Z3 MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMNPIDHVSFYCKTAPNRAIAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQ 4q7h D 2.59 BS02 ZN D 1 H167 H206 D207 D311 H53 H92 D93 D190 3.1.5.- Q9Y3Z3 MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMNPIDHVSFYCKTAPNRAIAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQ 4qg5 A 3.50 BS01 MG A 1 S118 D299 D301 D303 S94 D275 D277 D279 5.4.2.2 Q4QCF1 FQQPNYTANFVQSTFNALHRQGAVPDVLVVGGDGRYYTSEAVQVILKVSAANGVRCVWVGQHGLLSTPAVSTMVRRRRDADGRKATGAFILTASHNPGGPDADFGIKYNSENGGPAPEKLTSQIYEETVKITHIKMAPTLPEVDIHTLGTYTFDDYNFQVEVVDSLADYAAYMQEVFDFEAIRALVQRLDFKVHVDSLHGVSGPYVDRIFHEGLGVPKTSLFRTNVLPDFGGCHPDPNLTYAADLVHVMGLLPDGNANPAMKHISTVPSFGVAFDGDADRNMILGCRFFVNPSDSLAVLAANADCVPFFTQSSSSGLKAVARSMPTSGAVDRVAAAHDFALFEVPTGWKFFGNLMDSKDLYGGKDFNPLLCGEESFGTGSNHIREKDGIWASLFWLSVIAKRNAPGTPLVGVQQIVEEHWATYGRNYYSRYDYEDVSAEAAKAVMDTVENTVVDDVPNLNGVACKTIDNFSYTDPIDGSVSTKQGVRVLFEDGSRFVLRLSGTGSSGATIRLYLEQYMDSATVKSHLAEKTLPTASTALKALIGVALQVSKMESLTGRKTPTVIT 4qg5 B 3.50 BS01 MG B 1 S118 D299 D301 D303 S88 D269 D271 D273 5.4.2.2 Q4QCF1 TANFVQSTFNALHRQGAVPDVLVVGGDGRYYTSEAVQVILKVSAANGVRCVWVGQHGLLSTPAVSTMVRRRRDADGRKATGAFILTASHNPGGPDADFGIKYNSENGGPAPEKLTSQIYEETVKITHIKMAPTLPEVDIHTLGTYTFDDYNFQVEVVDSLADYAAYMQEVFDFEAIRALVQRLDFKVHVDSLHGVSGPYVDRIFHEGLGVPKTSLFRTNVLPDFGGCHPDPNLTYAADLVHVMGLLPDGNANPAMKHISTVPSFGVAFDGDADRNMILGCRFFVNPSDSLAVLAANADCVPFFTQSSSSGLKAVARSMPTSGAVDRVAAAHDFALFEVPTGWKFFGNLMDSKDLYGGKDFNPLLCGEESFGTGSNHIREKDGIWASLFWLSVIAKRNAPGTPLVGVQQIVEEHWATYGRNYYSRYDYEDVSAEAAKAVMDTVENTVVDDVPNLNGVACKTIDNFSYTDPIDGSVSTKQGVRVLFEDGSRFVLRLSGTGSSGATIRLYLEQYMDSATVKSHLAEKTLPTASTALKALIGVALQVSKMESLTGRKTPTVIT 4qg5 C 3.50 BS01 MG C 1 S118 D299 D301 D303 R304 S90 D271 D273 D275 R276 5.4.2.2 Q4QCF1 NYTANFVQSTFNALHRQGAVPDVLVVGGDGRYYTSEAVQVILKVSAANGVRCVWVGQHGLLSTPAVSTMVRRRRDADGRKATGAFILTASHNPGGPDADFGIKYNSENGGPAPEKLTSQIYEETVKITHIKMAPTLPEVDIHTLGTYTFDDYNFQVEVVDSLADYAAYMQEVFDFEAIRALVQRLDFKVHVDSLHGVSGPYVDRIFHEGLGVPKTSLFRTNVLPDFGGCHPDPNLTYAADLVHVMGLLPDGNANPAMKHISTVPSFGVAFDGDADRNMILGCRFFVNPSDSLAVLAANADCVPFFTQSSSSGLKAVARSMPTSGAVDRVAAAHDFALFEVPTGWKFFGNLMDSKDLYGGKDFNPLLCGEESFGTGSNHIREKDGIWASLFWLSVIAKRNAPGTPLVGVQQIVEEHWATYGRNYYSRYDYEDVSAEAAKAVMDTVENTVVDDVPNLNGVACKTIDNFSYTDPIDGSVSTKQGVRVLFEDGSRFVLRLSGTGSSGATIRLYLEQYMDSATVKSHLAEKTLPTASTALKALIGVALQVSKMESLTGRKTPTVIT 4qg5 D 3.50 BS01 MG D 1 S118 D299 D301 D303 S88 D269 D271 D273 5.4.2.2 Q4QCF1 TANFVQSTFNALHRQGAVPDVLVVGGDGRYYTSEAVQVILKVSAANGVRCVWVGQHGLLSTPAVSTMVRRRRDADGRKATGAFILTASHNPGGPDADFGIKYNSENGGPAPEKLTSQIYEETVKITHIKMAPTLPEVDIHTLGTYTFDDYNFQVEVVDSLADYAAYMQEVFDFEAIRALVQRLDFKVHVDSLHGVSGPYVDRIFHEGLGVPKTSLFRTNVLPDFGGCHPDPNLTYAADLVHVMGLLPDGNANPAMKHISTVPSFGVAFDGDADRNMILGCRFFVNPSDSLAVLAANADCVPFFTQSSSSGLKAVARSMPTSGAVDRVAAAHDFALFEVPTGWKFFGNLMDSKDLYGGKDFNPLLCGEESFGTGSNHIREKDGIWASLFWLSVIAKRNAPGTPLVGVQQIVEEHWATYGRNYYSRYDYEDVSAEAAKAVMDTVENTVVDDVPNLNGVACKTIDNFSYTDPIDGSVSTKQGVRVLFEDGSRFVLRLSGTGSSGATIRLYLEQYMDSATVKSHLAEKTLPTASTALKALIGVALQVSKMESLTGRKTPTVIT 4qgn A 3.05 BS01 FE A 1 H88 H90 E94 H133 H88 H90 E94 H133 1.13.11.54 Q9BV57 MVQAWYMDDAPGDPRQPHRPDPGRPVGLEQLRRLGVLYWKLDADKYENDPELEKIRRERNYSWMDIITICKDKLPNYEEKIKMFYEEHLHLDDEIRYILDGSGYFDVRDKEDQWIRIFMEKGDMVTLPAGIYHRFTVDEKNYTKAMRLFVGEPVWTAYNRPADHFEARGQYVKFLAQT 4qgn A 3.05 BS02 MSE A 1 M83 F84 H88 H90 E94 H133 F135 A157 M83 F84 H88 H90 E94 H133 F135 A157 1.13.11.54 Q9BV57 MVQAWYMDDAPGDPRQPHRPDPGRPVGLEQLRRLGVLYWKLDADKYENDPELEKIRRERNYSWMDIITICKDKLPNYEEKIKMFYEEHLHLDDEIRYILDGSGYFDVRDKEDQWIRIFMEKGDMVTLPAGIYHRFTVDEKNYTKAMRLFVGEPVWTAYNRPADHFEARGQYVKFLAQT 4qt1 A 2.40 BS01 3C9 A 1 L828 G829 K830 G831 V836 A853 V884 M902 E903 Y904 L905 C909 R953 L956 D967 L15 G16 K17 G18 V23 A40 V71 M83 E84 Y85 L86 C90 R134 L137 D148 2.7.10.2 P52333 25262541 PTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMPALSRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGS 4qvc D 1.99 BS01 NUC G 1 Y25 N28 G29 I30 K31 T61 V63 Y20 N23 G24 I25 K26 T56 V58 C1IFD2 25670676 SLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPS 4qvc E 1.99 BS01 NUC G 1 L26 I30 L32 Q52 L21 I25 L27 Q47 C1IFD2 25670676 SLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPS 4qvd D 1.97 BS01 NUC H 1 Y25 N28 G29 I30 K31 T61 V63 Y20 N23 G24 I25 K26 T56 V58 C1IFD2 25670676 SLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPS 4qvd E 1.97 BS01 NUC H 1 L26 I30 K31 L32 Q33 Q52 L21 I25 K26 L27 Q28 Q47 C1IFD2 25670676 SLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPS 4rcy A 1.65 BS01 GTP A 1 V18 A19 H20 G21 K22 T23 T24 M45 T46 G96 N149 K150 D152 V153 S184 A185 L186 V17 A18 H19 G20 K21 T22 T23 M44 T45 G95 N148 K149 D151 V152 S183 A184 L185 Q980A5 25690901 AWPKVQPEVNIGVVGHVAHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rcy A 1.65 BS02 MG A 1 T23 T46 T22 T45 Q980A5 25690901 AWPKVQPEVNIGVVGHVAHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rcy A 1.65 BS03 GDP A 1 F221 V223 K225 K234 S278 R280 G282 A296 G298 F220 V222 K224 K233 S277 R279 G281 A295 G297 Q980A5 25690901 AWPKVQPEVNIGVVGHVAHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rcz A 1.43 BS01 GNP A 1 V18 D19 H20 G21 K22 T23 T24 M45 T46 G96 N149 K150 D152 V153 S184 A185 L186 V17 D18 H19 G20 K21 T22 T23 M44 T45 G95 N148 K149 D151 V152 S183 A184 L185 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rcz A 1.43 BS02 MG A 1 T23 T46 T22 T45 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rcz A 1.43 BS03 GNP A 2 F221 V223 K225 K234 S278 R280 G282 D283 A296 G298 F220 V222 K224 K233 S277 R279 G281 D282 A295 G297 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd0 A 1.71 BS01 GDP A 1 A19 H20 G21 K22 T23 T24 N149 K150 D152 V153 S184 A185 L186 A18 H19 G20 K21 T22 T23 N148 K149 D151 V152 S183 A184 L185 Q980A5 25690901 AWPKVQPEVNIGVVGHVAHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd0 A 1.71 BS02 MG A 1 T23 T46 T22 T45 Q980A5 25690901 AWPKVQPEVNIGVVGHVAHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd0 A 1.71 BS03 GDP A 2 F221 V223 K225 K234 S278 R280 G282 A296 G298 F220 V222 K224 K233 S277 R279 G281 A295 G297 Q980A5 25690901 AWPKVQPEVNIGVVGHVAHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd1 A 1.50 BS01 GTP A 1 V18 D19 H20 G21 K22 T23 T24 M45 T46 G96 N149 K150 D152 V153 S184 A185 L186 V17 D18 H19 G20 K21 T22 T23 M44 T45 G95 N148 K149 D151 V152 S183 A184 L185 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd1 A 1.50 BS02 GDP A 1 D19 H20 G21 K22 T23 T24 N149 K150 D152 V153 S184 A185 L186 D18 H19 G20 K21 T22 T23 N148 K149 D151 V152 S183 A184 L185 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd1 A 1.50 BS03 MG A 1 T23 T46 T22 T45 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd1 A 1.50 BS04 MG A 2 D19 G44 D18 G43 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd1 A 1.50 BS05 GDP A 2 F221 V223 K225 K234 S278 R280 G282 A296 G298 F220 V222 K224 K233 S277 R279 G281 A295 G297 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd2 A 1.58 BS01 GNP A 1 V18 D19 H20 G21 K22 T23 T24 M45 T46 G96 N149 K150 D152 V153 S184 A185 L186 V17 D18 H19 G20 K21 T22 T23 M44 T45 G95 N148 K149 D151 V152 S183 A184 L185 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd2 A 1.58 BS02 MG A 1 T23 T46 T22 T45 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd2 A 1.58 BS03 GNP A 2 F221 D222 V223 K225 K234 S278 R280 G282 A296 G298 F220 D221 V222 K224 K233 S277 R279 G281 A295 G297 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd3 A 1.69 BS01 GDP A 1 D19 H20 G21 K22 T23 T24 N149 K150 D152 V153 S184 A185 L186 D18 H19 G20 K21 T22 T23 N148 K149 D151 V152 S183 A184 L185 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd3 A 1.69 BS02 MG A 1 T23 T46 T22 T45 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd3 A 1.69 BS03 GDP A 2 F221 V223 K234 S278 R280 G282 A296 G298 F220 V222 K233 S277 R279 G281 A295 G297 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGAEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd4 A 1.30 BS01 GNP A 1 V18 D19 H20 G21 K22 T23 T24 M45 T46 G96 N149 K150 D152 V153 S184 A185 L186 V17 D18 H19 G20 K21 T22 T23 M44 T45 G95 N148 K149 D151 V152 S183 A184 L185 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd4 A 1.30 BS02 MG A 1 T23 T46 T22 T45 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rd4 A 1.30 BS03 GNP A 2 V223 K225 K234 S278 R280 G282 A296 G298 V222 K224 K233 S277 R279 G281 A295 G297 Q980A5 25690901 AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI 4rvt A 2.40 BS01 3XM A 1 V31 Y36 V39 A52 M105 E106 F107 C108 G109 G111 L160 V170 D171 V18 Y23 V26 A39 M88 E89 F90 C91 G92 G94 L143 V153 D154 2.7.11.1 O95819 25908259 DLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRT 4ryd A 2.15 BS01 III H 1 D154 D191 N192 H194 V231 T232 E236 S253 W254 G255 P256 D258 D264 G265 A267 A292 S293 G294 D306 Y308 T309 T367 S368 D46 D83 N84 H86 V123 T124 E128 S145 W146 G147 P148 D150 D156 G157 A159 A184 S185 G186 D198 Y200 T201 T259 S260 3.4.21.75 P09958 25974265 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd A 2.15 BS02 CA A 1 D115 D162 V205 N208 V210 G212 D7 D54 V97 N100 V102 G104 3.4.21.75 P09958 25974265 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd A 2.15 BS03 CA A 2 D258 D301 E331 D150 D193 E223 3.4.21.75 P09958 25974265 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd A 2.15 BS04 CA A 3 D174 D179 D181 D66 D71 D73 3.4.21.75 P09958 25974265 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd B 2.15 BS01 III I 1 D154 D191 N192 H194 V231 T232 E236 S253 W254 G255 P256 D258 D264 G265 A292 S293 G294 D306 Y308 T309 T367 S368 D45 D82 N83 H85 V122 T123 E127 S144 W145 G146 P147 D149 D155 G156 A183 S184 G185 D197 Y199 T200 T258 S259 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd B 2.15 BS02 CA B 1 D115 D162 V205 N208 V210 G212 D6 D53 V96 N99 V101 G103 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd B 2.15 BS03 CA B 2 D258 D301 E331 D149 D192 E222 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd B 2.15 BS04 CA B 3 D174 D179 D181 D65 D70 D72 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd C 2.15 BS01 III J 1 D154 D191 N192 H194 V231 T232 E236 S253 W254 G255 P256 D258 D264 G265 A267 A292 S293 G294 D306 Y308 T309 T367 S368 D46 D83 N84 H86 V123 T124 E128 S145 W146 G147 P148 D150 D156 G157 A159 A184 S185 G186 D198 Y200 T201 T259 S260 3.4.21.75 P09958 25974265 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd C 2.15 BS02 CA C 1 D115 D162 V205 N208 V210 G212 D7 D54 V97 N100 V102 G104 3.4.21.75 P09958 25974265 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd C 2.15 BS03 CA C 2 D258 D301 E331 D150 D193 E223 3.4.21.75 P09958 25974265 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd C 2.15 BS04 CA C 3 D174 D179 D181 D66 D71 D73 3.4.21.75 P09958 25974265 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd D 2.15 BS01 III K 1 D154 D191 N192 H194 V231 T232 E236 S253 W254 G255 P256 D258 D264 G265 A267 A292 S293 G294 D306 Y308 T309 T367 S368 D45 D82 N83 H85 V122 T123 E127 S144 W145 G146 P147 D149 D155 G156 A158 A183 S184 G185 D197 Y199 T200 T258 S259 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd D 2.15 BS02 CA D 1 D115 D162 V205 N208 V210 G212 D6 D53 V96 N99 V101 G103 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd D 2.15 BS03 CA D 2 D258 D301 E331 D149 D192 E222 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd D 2.15 BS04 CA D 3 D174 D179 D181 D65 D70 D72 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd E 2.15 BS01 III L 1 D154 D191 N192 H194 V231 T232 E236 S253 W254 G255 P256 D258 D264 G265 A292 S293 G294 N295 D306 Y308 T309 T367 S368 D45 D82 N83 H85 V122 T123 E127 S144 W145 G146 P147 D149 D155 G156 A183 S184 G185 N186 D197 Y199 T200 T258 S259 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd E 2.15 BS02 CA E 1 D115 D162 V205 N208 V210 G212 D6 D53 V96 N99 V101 G103 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd E 2.15 BS03 CA E 2 D258 D301 E331 D149 D192 E222 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd E 2.15 BS04 CA E 3 D174 D179 D181 D65 D70 D72 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd F 2.15 BS01 III N 1 D154 D191 N192 H194 V231 T232 E236 S253 W254 G255 P256 D258 D264 G265 A267 A292 S293 G294 D306 Y308 T309 T367 S368 D45 D82 N83 H85 V122 T123 E127 S144 W145 G146 P147 D149 D155 G156 A158 A183 S184 G185 D197 Y199 T200 T258 S259 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd F 2.15 BS02 CA F 1 D115 D162 V205 N208 V210 G212 D6 D53 V96 N99 V101 G103 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd F 2.15 BS03 CA F 2 D258 D301 E331 D149 D192 E222 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryd F 2.15 BS04 CA F 3 D174 D179 D181 D65 D70 D72 3.4.21.75 P09958 25974265 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA 4ryx A 2.00 BS01 FE2 A 1 H180 H241 H313 H527 H165 H223 H290 H504 3.1.1.64 Q28175 QVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPDFRGVEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFGSIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4ryx A 2.00 BS02 A3V A 1 F61 F103 T129 V134 T147 E148 I259 F264 F279 F58 F100 T114 V119 T132 E133 I241 F246 F256 3.1.1.64 Q28175 QVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPDFRGVEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFGSIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4ryy A 2.30 BS01 FE2 A 1 H180 H241 H313 H527 H162 H218 H290 H504 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4ryy A 2.30 BS02 A3V A 1 F61 F103 T129 V134 T147 E148 T149 N194 H241 I259 Y275 Y338 F60 F102 T111 V116 T129 E130 T131 N176 H218 I236 Y252 Y315 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4ryy B 2.30 BS01 FE2 B 1 H180 H241 H313 H527 H162 H218 H290 H504 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4ryy B 2.30 BS02 A3V B 1 F61 F103 T129 V134 T147 E148 N194 H241 I259 Y275 Y338 F60 F102 T111 V116 T129 E130 N176 H218 I236 Y252 Y315 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4ryz A 2.50 BS01 FE2 A 1 H180 H241 H313 H527 H162 H218 H290 H504 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4ryz A 2.50 BS02 A5V A 1 F61 F103 T129 V134 T147 E148 N194 Y239 I259 Y275 Y338 F60 F102 T111 V116 T129 E130 N176 Y216 I236 Y252 Y315 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4ryz B 2.50 BS01 FE2 B 1 H180 H241 H313 H527 H162 H218 H290 H504 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4ryz B 2.50 BS02 A5V B 1 F61 F103 T129 V134 T147 E148 N194 Y239 Y275 Y338 F60 F102 T111 V116 T129 E130 N176 Y216 Y252 Y315 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4s0n A 1.50 BS01 NUC E 1 V68 G69 Y72 Y73 N91 Y93 D94 H110 L111 K112 K113 F142 V13 G14 Y17 Y18 N36 Y38 D39 H55 L56 K57 K58 F87 3.6.4.-,6.3.2.- Q14527 DSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPAPKT 4s0n A 1.50 BS02 DT A 1 Q86 R87 D88 P89 N90 K99 Q31 R32 D33 P34 N35 K44 3.6.4.-,6.3.2.- Q14527 DSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPAPKT 4s0n B 1.50 BS01 NUC E 1 G179 F180 G124 F125 3.6.4.-,6.3.2.- Q14527 DSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPAPKTLGF 4s0n B 1.50 BS02 NUC F 1 V68 G69 R71 Y72 Y73 N91 Y93 D94 H110 L111 K112 K113 F142 V13 G14 R16 Y17 Y18 N36 Y38 D39 H55 L56 K57 K58 F87 3.6.4.-,6.3.2.- Q14527 DSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPAPKTLGF 4s0n C 1.50 BS01 NUC G 1 V68 G69 Y72 Y73 N91 Y93 D94 A97 H110 L111 K112 K113 V18 G19 Y22 Y23 N41 Y43 D44 A47 H60 L61 K62 K63 3.6.4.-,6.3.2.- Q14527 GPGSVDSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPA 4s0n D 1.50 BS01 NUC E 1 S62 R64 H147 P173 S12 R14 H97 P123 3.6.4.-,6.3.2.- Q14527 GPGSVDSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPAPK 4s0n D 1.50 BS02 NUC H 1 V68 G69 Y72 Y73 N91 Y93 D94 H110 L111 K112 K113 V18 G19 Y22 Y23 N41 Y43 D44 H60 L61 K62 K63 3.6.4.-,6.3.2.- Q14527 GPGSVDSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPAPK 4udg A 1.60 BS01 PO4 A 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udg B 1.60 BS01 PO4 B 1 R150 N151 R168 K212 H231 Y242 R144 N145 R162 K206 H225 Y236 2.4.1.- D9ZDQ9 VIIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udg C 1.60 BS01 PO4 C 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udg D 1.60 BS01 PO4 D 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udg E 1.60 BS01 PO4 E 1 R150 N151 R168 K212 H231 Y242 R144 N145 R162 K206 H225 Y236 2.4.1.- D9ZDQ9 VIIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udg F 1.60 BS01 PO4 F 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj A 1.94 BS01 PO4 A 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj A 1.94 BS02 BMA A 1 N44 R59 D104 R150 Y242 F283 D304 N37 R52 D97 R143 Y235 F276 D297 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj B 1.94 BS01 PO4 B 1 R150 N151 R168 K212 H231 Y242 R144 N145 R162 K206 H225 Y236 2.4.1.- D9ZDQ9 VIIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj B 1.94 BS02 BMA B 1 N44 R59 D104 R150 Y242 F283 D304 N38 R53 D98 R144 Y236 F277 D298 2.4.1.- D9ZDQ9 VIIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj C 1.94 BS01 PO4 C 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj C 1.94 BS02 BMA C 1 N44 R59 D104 R150 Y242 F283 D304 N37 R52 D97 R143 Y235 F276 D297 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj D 1.94 BS01 PO4 D 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj D 1.94 BS02 BMA D 1 N44 R59 D104 R150 Y242 F283 D304 N37 R52 D97 R143 Y235 F276 D297 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj E 1.94 BS01 PO4 E 1 R150 N151 R168 K212 H231 Y242 R144 N145 R162 K206 H225 Y236 2.4.1.- D9ZDQ9 VIIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj E 1.94 BS02 BMA E 1 N44 R59 D104 R150 Y242 F283 D304 N38 R53 D98 R144 Y236 F277 D298 2.4.1.- D9ZDQ9 VIIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj F 1.94 BS01 PO4 F 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udj F 1.94 BS02 BMA F 1 N44 R59 D104 R150 Y242 F283 D304 N37 R52 D97 R143 Y235 F276 D297 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk A 1.76 BS01 PO4 A 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk A 1.76 BS02 BMA A 1 R59 Y103 D104 Y242 V281 F283 D304 R52 Y96 D97 Y235 V274 F276 D297 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk A 1.76 BS03 NDG A 1 R59 M67 Y103 H174 R52 M60 Y96 H167 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk B 1.76 BS01 PO4 B 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk B 1.76 BS02 BMA B 1 F43 R59 Y242 V281 F283 D304 F36 R52 Y235 V274 F276 D297 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk B 1.76 BS03 NDG B 1 R59 M67 R150 H174 R52 M60 R143 H167 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk C 1.76 BS01 PO4 C 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk C 1.76 BS02 BMA C 1 R59 D104 Y242 V281 F283 D304 R52 D97 Y235 V273 F275 D296 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk C 1.76 BS03 NDG C 1 R59 M67 H174 R52 M60 H167 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk D 1.76 BS01 PO4 D 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk D 1.76 BS02 BMA D 1 R59 Y103 D104 Y242 V281 F283 D304 R52 Y96 D97 Y235 V274 F276 D297 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk D 1.76 BS03 NDG D 1 R59 M67 Y103 R150 H174 R52 M60 Y96 R143 H167 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk E 1.76 BS01 PO4 E 1 R150 N151 R168 K212 H231 Y242 R144 N145 R162 K206 H225 Y236 2.4.1.- D9ZDQ9 IIIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk E 1.76 BS02 BMA E 1 R59 D104 Y242 V281 F283 D304 R53 D98 Y236 V275 F277 D298 2.4.1.- D9ZDQ9 IIIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk E 1.76 BS03 NDG E 1 R59 M67 Y103 R150 H174 R53 M61 Y97 R144 H168 2.4.1.- D9ZDQ9 IIIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk F 1.76 BS01 PO4 F 1 R150 N151 R168 K212 H231 Y242 R143 N144 R161 K205 H224 Y235 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk F 1.76 BS02 BMA F 1 R59 D104 Y242 V281 F283 D304 R52 D97 Y235 V274 F276 D297 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4udk F 1.76 BS03 NDG F 1 R59 M67 Y103 R150 H174 R52 M60 Y96 R143 H167 2.4.1.- D9ZDQ9 IIPWEERPAGCKDVLWRSVANPIIPRDLLPTSNSIFNSAVVPFGDGFAGVFRCDDTSRRMRLHVGFSKDAINWNIKEEPLKFQCDDEEIGTWVYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAFIPFNRNGVLFPRKINGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAAFEVSAWQCTKIGAGPIPVETPEGWLLIYHGVLHSCNGYVYSFGSALLDLDEPWKVKFRSGPYLLAPREPYECMGDVPNVCFPCAALHDNETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII 4usc A 2.60 BS01 CA A 1 S170 D223 T226 V229 D231 S170 D223 T226 V229 D231 25660651 DLQIGFYNQSCPSAESLVQQGVAAAFANNSGIAPGLIRMHFHDCFVRGCDGSVLLDSTDTNTAEKDAAPNNPSLRGFEVIAAAKSAVEAACPKTVSCADILAFAARDSAALAGNITYQVPSGRRDGNVSLASEALTNIPAPTFNATQLINSFAGKNLTADEMVTLSGAHSIGVSHCFSFLNRIYNFSNTSQVDPTLSSSYADLLRTKCPSNSTRFTPITVSLDIITPTVLDNRYYTGVQLTLGLLTSDQALVTEANLSAAVKNNADNLTAWVAEFAQAIVKMGQIEVLTGTQGEIRTNCSVVN 4usc A 2.60 BS02 CA A 2 D43 V46 G48 D50 S52 D43 V46 G48 D50 S52 25660651 DLQIGFYNQSCPSAESLVQQGVAAAFANNSGIAPGLIRMHFHDCFVRGCDGSVLLDSTDTNTAEKDAAPNNPSLRGFEVIAAAKSAVEAACPKTVSCADILAFAARDSAALAGNITYQVPSGRRDGNVSLASEALTNIPAPTFNATQLINSFAGKNLTADEMVTLSGAHSIGVSHCFSFLNRIYNFSNTSQVDPTLSSSYADLLRTKCPSNSTRFTPITVSLDIITPTVLDNRYYTGVQLTLGLLTSDQALVTEANLSAAVKNNADNLTAWVAEFAQAIVKMGQIEVLTGTQGEIRTNCSVVN 4usc A 2.60 BS03 HEM A 1 P34 G35 R38 F41 R75 P139 A140 P141 F152 L165 A168 H169 G172 V173 S174 H175 S178 L222 L245 M282 P34 G35 R38 F41 R75 P139 A140 P141 F152 L165 A168 H169 G172 V173 S174 H175 S178 L222 L245 M282 25660651 DLQIGFYNQSCPSAESLVQQGVAAAFANNSGIAPGLIRMHFHDCFVRGCDGSVLLDSTDTNTAEKDAAPNNPSLRGFEVIAAAKSAVEAACPKTVSCADILAFAARDSAALAGNITYQVPSGRRDGNVSLASEALTNIPAPTFNATQLINSFAGKNLTADEMVTLSGAHSIGVSHCFSFLNRIYNFSNTSQVDPTLSSSYADLLRTKCPSNSTRFTPITVSLDIITPTVLDNRYYTGVQLTLGLLTSDQALVTEANLSAAVKNNADNLTAWVAEFAQAIVKMGQIEVLTGTQGEIRTNCSVVN 4usc B 2.60 BS01 CA B 1 D43 V46 G48 D50 S52 D43 V46 G48 D50 S52 25660651 DLQIGFYNQSCPSAESLVQQGVAAAFANNSGIAPGLIRMHFHDCFVRGCDGSVLLDSTDTNTAEKDAAPNNPSLRGFEVIAAAKSAVEAACPKTVSCADILAFAARDSAALAGNITYQVPSGRRDGNVSLASEALTNIPAPTFNATQLINSFAGKNLTADEMVTLSGAHSIGVSHCFSFLNRIYNFSNTSQVDPTLSSSYADLLRTKCPSNSTRFTPITVSLDIITPTVLDNRYYTGVQLTLGLLTSDQALVTEANLSAAVKNNADNLTAWVAEFAQAIVKMGQIEVLTGTQGEIRTNCSVVN 4usc B 2.60 BS02 CA B 2 S170 D223 T226 V229 D231 S170 D223 T226 V229 D231 25660651 DLQIGFYNQSCPSAESLVQQGVAAAFANNSGIAPGLIRMHFHDCFVRGCDGSVLLDSTDTNTAEKDAAPNNPSLRGFEVIAAAKSAVEAACPKTVSCADILAFAARDSAALAGNITYQVPSGRRDGNVSLASEALTNIPAPTFNATQLINSFAGKNLTADEMVTLSGAHSIGVSHCFSFLNRIYNFSNTSQVDPTLSSSYADLLRTKCPSNSTRFTPITVSLDIITPTVLDNRYYTGVQLTLGLLTSDQALVTEANLSAAVKNNADNLTAWVAEFAQAIVKMGQIEVLTGTQGEIRTNCSVVN 4usc B 2.60 BS03 HEM B 1 P34 G35 R38 F41 R75 P139 A140 P141 F152 L165 A168 H169 G172 V173 S174 H175 S178 L222 L245 M282 P34 G35 R38 F41 R75 P139 A140 P141 F152 L165 A168 H169 G172 V173 S174 H175 S178 L222 L245 M282 25660651 DLQIGFYNQSCPSAESLVQQGVAAAFANNSGIAPGLIRMHFHDCFVRGCDGSVLLDSTDTNTAEKDAAPNNPSLRGFEVIAAAKSAVEAACPKTVSCADILAFAARDSAALAGNITYQVPSGRRDGNVSLASEALTNIPAPTFNATQLINSFAGKNLTADEMVTLSGAHSIGVSHCFSFLNRIYNFSNTSQVDPTLSSSYADLLRTKCPSNSTRFTPITVSLDIITPTVLDNRYYTGVQLTLGLLTSDQALVTEANLSAAVKNNADNLTAWVAEFAQAIVKMGQIEVLTGTQGEIRTNCSVVN 4uxh A 2.40 BS01 T5A A 1 M13 F14 A15 G16 K17 T18 T19 M22 K39 D43 R45 Y46 E85 Q87 F88 L111 D114 Y115 F120 T151 R153 Q160 E161 L162 I163 G164 Y169 M11 F12 A13 G14 K15 T16 T17 M20 K37 D41 R43 Y44 E79 Q81 F82 L105 D108 Y109 F114 T145 R147 Q154 E155 L156 I157 G158 Y163 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDEHNVALMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxh A 2.40 BS02 ZN A 1 C140 C143 C173 C176 C134 C137 C167 C170 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDEHNVALMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxh B 2.40 BS01 T5A B 1 M13 F14 A15 G16 K17 T18 M22 K39 D43 E85 Q87 F88 L111 D114 Y115 F120 T151 R153 Q160 E161 L162 I163 G164 Y169 M11 F12 A13 G14 K15 T16 M20 K37 D41 E68 Q70 F71 L94 D97 Y98 F103 T134 R136 Q143 E144 L145 I146 G147 Y152 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQQ 4uxh B 2.40 BS02 ZN B 1 C140 C143 C173 C176 C123 C126 C156 C159 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQQ 4uxi A 2.74 BS01 THM A 1 M13 E85 L111 D114 Y115 F120 T151 Q160 E161 L162 I163 G164 Y169 M12 E68 L94 D97 Y98 F103 T134 Q143 E144 L145 I146 G147 Y152 2.7.1.21 Q4QC75 25978379 FRGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQQ 4uxi A 2.74 BS02 ZN A 1 C140 C143 C173 C176 C123 C126 C156 C159 2.7.1.21 Q4QC75 25978379 FRGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQQ 4uxi B 2.74 BS01 THM B 1 M13 E85 Q87 F88 L111 D114 Y115 F120 T151 Q160 E161 L162 G164 Y169 M11 E65 Q67 F68 L91 D94 Y95 F100 T131 Q140 E141 L142 G144 Y149 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQ 4uxi B 2.74 BS02 ZN B 1 C140 C143 C173 C176 C120 C123 C153 C156 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQ 4uxj A 3.00 BS01 ZN A 1 C140 C143 C173 C176 C125 C128 C158 C161 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSDQLMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQQL 4uxj A 3.00 BS02 TTP A 1 M13 F14 A15 G16 K17 T18 E85 F88 L111 D114 Y115 F120 T151 Q160 E161 L162 I163 G164 Y169 M11 F12 A13 G14 K15 T16 E70 F73 L96 D99 Y100 F105 T136 Q145 E146 L147 I148 G149 Y154 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSDQLMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQQL 4uxj B 3.00 BS01 ZN B 1 C140 C143 C173 C176 C127 C130 C160 C163 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSSHDQLMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj B 3.00 BS02 TTP B 1 M13 F14 A15 G16 K17 T18 E85 F88 L111 D114 Y115 F120 T151 Q160 E161 L162 G164 Y169 M11 F12 A13 G14 K15 T16 E72 F75 L98 D101 Y102 F107 T138 Q147 E148 L149 G151 Y156 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSSHDQLMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj C 3.00 BS01 ZN C 1 C140 C143 C173 C176 C132 C135 C165 C168 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDEHNVALRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj C 3.00 BS02 TTP C 1 M13 F14 A15 G16 K17 T18 E85 F88 L111 D114 Y115 F120 T151 Q160 E161 L162 I163 G164 Y169 M11 F12 A13 G14 K15 T16 E77 F80 L103 D106 Y107 F112 T143 Q152 E153 L154 I155 G156 Y161 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDEHNVALRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj D 3.00 BS01 ZN D 1 C140 C143 C173 C176 C120 C123 C153 C156 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj D 3.00 BS02 TTP D 1 M13 F14 A15 G16 K17 T18 E85 F88 L111 D114 Y115 F120 T151 Q160 E161 L162 I163 G164 Y169 M11 F12 A13 G14 K15 T16 E65 F68 L91 D94 Y95 F100 T131 Q140 E141 L142 I143 G144 Y149 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj E 3.00 BS01 ZN E 1 C140 C143 C173 C176 C131 C134 C164 C167 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDEHNVASAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj E 3.00 BS02 TTP E 1 M13 F14 A15 G16 K17 T18 E85 F88 L111 D114 Y115 F120 T151 Q160 E161 L162 G164 Y169 M11 F12 A13 G14 K15 T16 E76 F79 L102 D105 Y106 F111 T142 Q151 E152 L153 G155 Y160 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDEHNVASAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj F 3.00 BS01 ZN F 1 C140 C143 C173 C176 C132 C135 C165 C168 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDHDQLMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQQ 4uxj F 3.00 BS02 TTP F 1 M13 F14 A15 G16 K17 T18 E85 M11 F12 A13 G14 K15 T16 E77 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDHDQLMLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSKQQ 4uxj G 3.00 BS01 ZN G 1 C140 C143 C173 C176 C130 C133 C163 C166 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDEHNLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj G 3.00 BS02 TTP G 1 M13 F14 A15 G16 K17 T18 E85 Q87 F88 L111 D114 Y115 F120 T151 Q160 E161 L162 G164 Y169 M11 F12 A13 G14 K15 T16 E75 Q77 F78 L101 D104 Y105 F110 T141 Q150 E151 L152 G154 Y159 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYSKDTRYDEHNLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECYSK 4uxj H 3.00 BS01 ZN H 1 C140 C143 C173 C176 C120 C123 C153 C156 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECY 4uxj H 3.00 BS02 TTP H 1 M13 F14 A15 G16 K17 T18 F88 L111 D114 Y115 F120 T151 Q160 E161 L162 I163 G164 Y169 M11 F12 A13 G14 K15 T16 F68 L91 D94 Y95 F100 T131 Q140 E141 L142 I143 G144 Y149 2.7.1.21 Q4QC75 25978379 RGRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIKYLRAQAAVSQLTEVRDTWKRFDVLAIDEGQFFSDLVDFCNTAADAGKVVMVSALDGDYRRKPFGQICELVPYCEAVDKLTAVCMMCHEQPACFTRRTVNVEQQELIGGADMYIATCRECY 4wri A 1.40 BS01 OKA A 1 F37 R44 F48 M58 R61 H65 S107 S108 T110 F111 A128 L131 G132 V135 F147 M150 Q167 F171 V184 R185 F34 R41 F45 M55 R58 H62 S104 S105 T107 F108 A125 L128 G129 V132 F144 M147 Q164 F168 V181 R182 Q2MHR1 25965326 LKEPSAHWCRKMRTVFRPWDVEGGSKGYVTEEVFKDGVQRRLEKFPELAPTKDKMYERSHRHWVNHCNLGVKMPEGYRLTESQYVQNAWLLIHSPDFEASLKESSQTFWEGIDREKKGYITKEEATKLGIRVTKDPNLKSTGIFEAMDEKNTGRITFEDTLKAQLFFFTDQDNTTHPFNYVRGALVD 4x36 A 2.10 BS01 ZN A 1 H26 H133 D149 H26 H133 D149 3.5.1.28 P06653 MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK 4xo0 A 1.70 BS01 NUC B 1 Y64 R116 Y41 R86 2.7.7.49,2.7.7.7,3.1.26.4 P03355 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 4xo0 A 1.70 BS02 NUC G 1 L99 Q113 D114 L115 R116 G191 L76 Q83 D84 L85 R86 G161 2.7.7.49,2.7.7.7,3.1.26.4 P03355 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 4xpc A 1.68 BS01 NUC B 1 Y64 P100 V101 R116 K120 Y41 P77 V78 R88 K92 2.7.7.49,2.7.7.7,3.1.26.4 P03355 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVKDYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPESGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 4xpc A 1.68 BS02 NUC G 1 L99 Q113 D114 L115 R116 G191 L76 Q85 D86 L87 R88 G160 2.7.7.49,2.7.7.7,3.1.26.4 P03355 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVKDYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPESGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 4xpe A 1.78 BS01 NUC B 1 Y64 L99 P100 V101 R116 Y41 L76 P77 V78 R88 2.7.7.49,2.7.7.7,3.1.26.4 P03355 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVKDYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPSGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 4xpe A 1.78 BS02 NUC G 1 L99 Q113 D114 L115 R116 G191 L76 Q85 D86 L87 R88 G159 2.7.7.49,2.7.7.7,3.1.26.4 P03355 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVKDYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPSGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 4y2d A 3.05 BS01 7DW A 1 C12 Q14 S28 W40 I47 F70 Y73 S76 D80 F120 W133 L143 L150 D153 G155 T156 V160 C7 Q9 S23 W35 I42 F65 Y68 S71 D75 F115 W128 L138 L145 D148 G150 T151 V155 P11609 KNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPQLVCHVSGFYPKPVWVTHRGDFLPNADETWYLQATLDGEEAGLACRVKHSSLGGQDI 4y2d C 3.05 BS01 7DW A 1 P29 N31 R95 G96 P28 N30 R94 G95 TQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKDFACANAFNNSIIPEDTFFPS 4y2d E 3.05 BS01 FU4 E 1 S114 W129 G130 L164 S109 W124 G125 L159 P11609 KNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPQLVCHVSGFYPKPVWVMEQQGTHRGDFLPNADETWYLQCRVKHSSLGGQDI 4y2d E 3.05 BS02 7DW E 1 C12 Q14 S28 F70 V72 Y73 S76 D80 I81 L84 I98 W133 L150 D153 G155 T156 V160 C7 Q9 S23 F65 V67 Y68 S71 D75 I76 L79 I93 W128 L145 D148 G150 T151 V155 P11609 KNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPQLVCHVSGFYPKPVWVMEQQGTHRGDFLPNADETWYLQCRVKHSSLGGQDI 4y2d G 3.05 BS01 7DW E 1 P29 N31 R95 G96 P28 N30 R94 G95 TQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKDFACANAFNNSIIPEDTFFPS 4y4f A 3.19 BS01 49M A 1 C12 Q14 S28 V30 W63 L66 F70 Y73 S76 F77 D80 A102 L116 V118 F120 W133 L143 L150 D153 G155 T156 V160 L163 L164 C168 F171 C6 Q8 S22 V24 W57 L60 F64 Y67 S70 F71 D74 A96 L110 V112 F114 W127 L137 L144 D147 G149 T150 V154 L157 L158 C162 F165 P11609 NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 4y4f C 3.19 BS01 49M A 1 P29 N31 D94 R95 G96 P28 N30 D93 R94 G95 TQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKDFACANAFNNSIIPEDTFFPS 4y4f E 3.19 BS01 49M E 1 C12 Q14 S28 V30 I47 W63 F70 Y73 S76 D80 L100 A102 F120 W133 L143 L150 D153 G155 T156 V160 L163 L164 C168 F171 C6 Q8 S22 V24 I41 W57 F64 Y67 S70 D74 L94 A96 F114 W127 L137 L144 D147 G149 T150 V154 L157 L158 C162 F165 P11609 NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 4y4f G 3.19 BS01 49M E 1 P29 N31 D94 R95 G96 P28 N30 D93 R94 G95 TQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKDFACANAFNNSIIPEDTFFPS 4y4h A 3.10 BS01 49X A 1 Q14 Y73 S76 F77 D80 A102 W133 L150 D153 G155 T156 Q8 Y67 S70 F71 D74 A96 W127 L144 D147 G149 T150 P11609 NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 4y4h C 3.10 BS01 49X A 1 P29 N31 R95 G96 P28 N30 R94 G95 TQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKDFACANAFNNSIIPEDTFFPS 4y4h E 3.10 BS01 49X E 1 C12 Q14 Y73 F77 D80 L84 L100 A102 V118 W133 L150 D153 G155 T156 C6 Q8 Y67 F71 D74 L78 L94 A96 V112 W127 L144 D147 G149 T150 P11609 NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 4y4h G 3.10 BS01 49X E 1 P29 N31 R95 G96 P28 N30 R94 G95 TQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKDFACANAFNNSIIPEDTFFPS 4y4k A 2.90 BS01 FUC A 1 S114 F128 W129 G130 L164 N165 S109 F123 W124 G125 L159 N160 P11609 KNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 4y4k A 2.90 BS02 49Y A 1 C12 Q14 S28 V30 L66 M69 F70 Y73 S76 F77 D80 I81 L84 W133 D153 G155 T156 V160 L163 C7 Q9 S23 V25 L61 M64 F65 Y68 S71 F72 D75 I76 L79 W128 D148 G150 T151 V155 L158 P11609 KNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 4y4k C 2.90 BS01 49Y A 1 P28 N30 R94 G95 P28 N30 R94 G95 TQVEQSPQSLVVRQGENCVLQCNYSVTPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVGDRGSALGRLHFGAGTQLIVIPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKDFACANAFNNSIIPEDTFFPS 4y8x A 1.90 BS01 4GR A 1 R39 H40 L41 C42 H57 C58 Y143 L147 I151 D189 A190 C191 K192 G193 D194 S195 T213 W215 G216 G218 C219 G226 V227 Y228 R26 H27 L28 C29 H44 C45 Y134 L137 I141 D182 A183 C184 K185 G186 D187 S188 T206 W208 G209 G211 C212 G219 V220 Y221 3.4.21.27 P03951 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVGYGDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV 4y8y A 2.60 BS01 4D5 A 1 R39 H40 L41 H57 Y58B Y143 L147 I151 D189 A190 C191 K192 G193 D194 S195 T213 W215 G216 G218 C219 G226 V227 Y228 R26 H27 L28 H44 Y47 Y134 L137 I141 D182 A183 C184 K185 G186 D187 S188 T206 W208 G209 G211 C212 G219 V220 Y221 3.4.21.27 P03951 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVGYGDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV 4y8z A 2.20 BS01 4CE A 1 R39 H40 L41 C42 H57 C58 Y58B Y143 I151 D189 A190 C191 K192 G193 D194 S195 T213 W215 G216 G218 C219 G226 V227 R26 H27 L28 C29 H44 C45 Y47 Y134 I141 D182 A183 C184 K185 G186 D187 S188 T206 W208 G209 G211 C212 G219 V220 3.4.21.27 P03951 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVGYGDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV 4yj0 A 3.81 BS01 NUC D 1 P74 K75 A77 R80 I108 R111 Q112 R123 P5 K6 A8 R11 I39 R42 Q43 R54 Q9Y5R6 SPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 A 3.81 BS02 NUC E 1 L73 K89 G90 K92 R93 L4 K20 G21 K23 R24 Q9Y5R6 SPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 A 3.81 BS03 ZN A 1 H82 C100 C102 C105 H13 C31 C33 C36 Q9Y5R6 SPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 A 3.81 BS04 ZN A 2 C76 C79 H91 C95 C7 C10 H22 C26 Q9Y5R6 SPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 B 3.81 BS01 NUC D 1 R72 P74 K89 G90 K92 R93 R122 R4 P6 K21 G22 K24 R25 R54 Q9Y5R6 KSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 B 3.81 BS02 NUC E 1 S70 R72 K75 A77 R80 R111 Q112 V119 R123 S2 R4 K7 A9 R12 R43 Q44 V51 R55 Q9Y5R6 KSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 B 3.81 BS03 ZN B 1 H82 C100 C102 C105 H14 C32 C34 C37 Q9Y5R6 KSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 B 3.81 BS04 ZN B 2 C76 C79 H91 C95 C8 C11 H23 C27 Q9Y5R6 KSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 C 3.81 BS01 NUC D 1 R72 K75 A77 R80 R111 Q112 M115 R123 R4 K7 A9 R12 R43 Q44 M47 R55 Q9Y5R6 KSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 C 3.81 BS02 NUC E 1 R72 P74 K89 K92 M115 Q118 V119 R122 R4 P6 K21 K24 M47 Q50 V51 R54 Q9Y5R6 KSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 C 3.81 BS03 ZN C 1 H82 C100 C102 C105 H14 C32 C34 C37 Q9Y5R6 KSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj0 C 3.81 BS04 ZN C 2 C76 C79 H91 C95 C8 C11 H23 C27 Q9Y5R6 KSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEEL 4yj2 A 2.60 BS01 GTP A 1 G10 Q11 A12 Q15 D98 A99 N101 S140 G142 G143 G144 T145 G146 V177 S178 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 N101 S140 G142 G143 G144 T145 G146 V177 S178 E183 N206 Y224 N228 I231 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 4yj2 A 2.60 BS02 CA A 1 D39 T41 G44 E55 D39 T41 G44 E55 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 4yj2 B 2.60 BS01 GDP B 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 V175 D177 E181 N204 Y222 N226 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 4yj2 B 2.60 BS02 MG B 1 Q11 D179 Q11 D177 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 4yj2 B 2.60 BS03 4ED B 1 Y52 Q136 N167 F169 E200 Y202 V238 T239 C241 L242 L248 L252 L255 A316 I318 K352 A354 I378 Y50 Q134 N165 F167 E198 Y200 V236 T237 C239 L240 L246 L250 L253 A308 I310 K344 A346 I362 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 4yj2 C 2.60 BS01 GTP C 1 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G143 G144 T145 G146 I171 V177 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G143 G144 T145 G146 I171 V177 E183 N206 Y224 N228 I231 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4yj2 C 2.60 BS02 CA C 1 D39 T41 G44 E55 D39 T41 G44 E55 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4yj2 D 2.60 BS01 GDP D 1 G10 Q11 C12 Q15 N101 S140 G143 G144 T145 G146 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 N99 S138 G141 G142 T143 G144 V175 D177 E181 N204 Y222 N226 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 4yj2 D 2.60 BS02 MG D 1 Q11 D179 Q11 D177 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 4yj2 D 2.60 BS03 4ED D 1 Q136 N167 F169 E200 Y202 V238 T239 C241 L242 L252 L255 A316 I318 K352 A354 I378 Q134 N165 F167 E198 Y200 V236 T237 C239 L240 L250 L253 A304 I306 K340 A342 I358 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 4yj3 A 3.75 BS01 GTP A 1 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G142 G143 G144 T145 V177 S178 T179 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G142 G143 G144 T145 V177 S178 T179 E183 N206 Y224 N228 I231 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVD 4yj3 A 3.75 BS02 CA A 1 D39 T41 G44 G45 F49 N50 E55 D39 T41 G44 G45 F49 N50 E55 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVD 4yj3 A 3.75 BS03 4EE B 1 T179 V181 T179 V181 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVD 4yj3 B 3.75 BS01 GDP B 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 V175 D177 E181 N204 Y222 N226 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 4yj3 B 3.75 BS02 4EE B 1 C241 L248 A250 K254 L255 N258 M259 T314 V315 A316 A317 I318 N350 K352 A354 I378 C239 L246 A248 K252 L253 N256 M257 T306 V307 A308 A309 I310 N342 K344 A346 I362 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 4yj3 B 3.75 BS03 CA B 1 E110 E113 E108 E111 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 4yj3 C 3.75 BS01 MG C 1 Q11 E71 Q11 E71 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4yj3 C 3.75 BS02 GTP C 1 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G143 G144 T145 G146 I171 T179 E183 N206 Y224 N228 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G143 G144 T145 G146 I171 T179 E183 N206 Y224 N228 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4yj3 C 3.75 BS03 CA C 1 D39 T41 G44 E55 D39 T41 G44 E55 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4yj3 C 3.75 BS04 4EE D 1 A180 V181 A180 V181 P81947 25970265 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4yj3 D 3.75 BS01 GDP D 1 G10 Q11 C12 Q15 N101 S140 G143 G144 T145 G146 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 N99 S138 G141 G142 T143 G144 V175 D177 E181 N204 Y222 N226 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 4yj3 D 3.75 BS02 MG D 1 Q11 N101 D179 Q11 N99 D177 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 4yj3 D 3.75 BS03 4EE D 1 C241 L242 L248 A250 D251 K254 L255 N258 T314 V315 A316 A317 I318 N350 K352 A354 I378 C239 L240 L246 A248 D249 K252 L253 N256 T302 V303 A304 A305 I306 N338 K340 A342 I358 Q6B856 25970265 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 4ymg A 1.90 BS01 SAM A 1 K47 M48 S49 G73 Y75 Y78 S79 E98 Y99 G125 P126 A127 E128 D144 A145 N146 Y153 K46 M47 S48 G72 Y74 Y77 S78 E97 Y98 G124 P125 A126 E127 D143 A144 N145 Y152 Q9HGR1 LGSILPFNEETADRVSAYCEKNSHGIPDALVEHWEWTRTRFPDADKMSSRLQGSWMIFTARDRKPKRILEIGCYSGYSALAWYEGTRDTKAEIVTLEYSPKMIAASREAFKKYGVGDRVKLIEGPAENTLKTLEGEFDLIFVDANKDGYAGYVKTILDQGLLSANGIILCDNVFARGLTIGPDCAPWLNDHVRPYWNGCGQALDKFSAGLMEDPRIDVLLLPVFDGVTQIRWKD 4ymg B 1.90 BS01 SAM B 1 K47 M48 S49 G73 Y75 Y78 S79 E98 Y99 G125 P126 A127 E128 D144 A145 N146 Y153 K46 M47 S48 G72 Y74 Y77 S78 E97 Y98 G124 P125 A126 E127 D143 A144 N145 Y152 Q9HGR1 LGSILPFNEETADRVSAYCEKNSHGIPDALVEHWEWTRTRFPDADKMSSRLQGSWMIFTARDRKPKRILEIGCYSGYSALAWYEGTRDTKAEIVTLEYSPKMIAASREAFKKYGVGDRVKLIEGPAENTLKTLEGEFDLIFVDANKDGYAGYVKTILDQGLLSANGIILCDNVFARGLTIGPDCAPWLNDHVRPYWNGCGQALDKFSAGLMEDPRIDVLLLPVFDGVTQIRWKDGAQRA 4ymh A 1.88 BS01 SAH A 1 K47 M48 S49 G73 Y75 Y78 S79 E98 Y99 A127 E128 D144 A145 N146 Y153 K46 M47 S48 G72 Y74 Y77 S78 E97 Y98 A126 E127 D143 A144 N145 Y152 Q9HGR1 LGSILPFNEETADRVSAYCEKNSHGIPDALVEHWEWTRTRFPDADKMSSRLQGSWMIFTARDRKPKRILEIGCYSGYSALAWYEGTRDTKAEIVTLEYSPKMIAASREAFKKYGVGDRVKLIEGPAENTLKTLEGEFDLIFVDANKDGYAGYVKTILDQGLLSANGIILCDNVFARGLTIGPDCAPWLNDHVRPYWNGCGQALDKFSAGLMEDPRIDVLLLPVFDGVTQIRWKDGAQRA 4ymh B 1.88 BS01 SAH B 1 K47 M48 S49 G73 Y75 S79 E98 Y99 G125 P126 A127 E128 D144 A145 N146 Y153 K46 M47 S48 G72 Y74 S78 E97 Y98 G124 P125 A126 E127 D143 A144 N145 Y152 Q9HGR1 LGSILPFNEETADRVSAYCEKNSHGIPDALVEHWEWTRTRFPDADKMSSRLQGSWMIFTARDRKPKRILEIGCYSGYSALAWYEGTRDTKAEIVTLEYSPKMIAASREAFKKYGVGDRVKLIEGPAENTLKTLEGEFDLIFVDANKDGYAGYVKTILDQGLLSANGIILCDNVFARGLTIGPDCAPWLNDHVRPYWNGCGQALDKFSAGLMEDPRIDVLLLPVFDGVTQIRWKDG 4ymh C 1.88 BS01 SAH C 1 K47 M48 S49 G73 Y75 S79 E98 Y99 S100 P126 A127 E128 D144 A145 N146 Y153 K46 M47 S48 G72 Y74 S78 E97 Y98 S99 P125 A126 E127 D143 A144 N145 Y152 Q9HGR1 LGSILPFNEETADRVSAYCEKNSHGIPDALVEHWEWTRTRFPDADKMSSRLQGSWMIFTARDRKPKRILEIGCYSGYSALAWYEGTRDTKAEIVTLEYSPKMIAASREAFKKYGVGDRVKLIEGPAENTLKTLEGEFDLIFVDANKDGYAGYVKTILDQGLLSANGIILCDNVFARGLTIGPDCAPWLNDHVRPYWNGCGQALDKFSAGLMEDPRIDVLLLPVFDGVTQIRWKDG 4ymh D 1.88 BS01 SAH D 1 K47 M48 S49 G73 Y75 Y78 S79 E98 Y99 A127 E128 D144 A145 N146 Y153 K46 M47 S48 G72 Y74 Y77 S78 E97 Y98 A126 E127 D143 A144 N145 Y152 Q9HGR1 LGSILPFNEETADRVSAYCEKNSHGIPDALVEHWEWTRTRFPDADKMSSRLQGSWMIFTARDRKPKRILEIGCYSGYSALAWYEGTRDTKAEIVTLEYSPKMIAASREAFKKYGVGDRVKLIEGPAENTLKTLEGEFDLIFVDANKDGYAGYVKTILDQGLLSANGIILCDNVFARGLTIGPDCAPWLNDHVRPYWNGCGQALDKFSAGLMEDPRIDVLLLPVFDGVTQIRWKD 4ynq A 2.80 BS01 NUC E 1 N18 L19 E20 A21 L24 I84 T85 H124 N125 R128 Y129 S176 Y177 S178 L179 H195 N14 L15 E16 A17 L20 I80 T81 H120 N121 R124 Y125 S168 Y169 S170 L171 H187 3.1.11.2 Q91XB0 25848017 TLPHGHMQTLIFLNLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASNGSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 4ynq A 2.80 BS02 NUC F 1 R128 K160 R174 R124 K156 R166 3.1.11.2 Q91XB0 25848017 TLPHGHMQTLIFLNLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASNGSRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 4ynq D 2.80 BS01 NUC G 1 N18 L19 E20 A21 G23 L24 T85 H124 N125 R128 Y129 S176 Y177 S178 L179 H195 N14 L15 E16 A17 G19 L20 T81 H120 N121 R124 Y125 S165 Y166 S167 L168 H184 3.1.11.2 Q91XB0 25848017 TLPHGHMQTLIFLNLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 4ynq D 2.80 BS02 NUC H 1 R128 R174 R124 R163 3.1.11.2 Q91XB0 25848017 TLPHGHMQTLIFLNLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 4ynq D 2.80 BS03 MG D 1 N18 H124 N14 H120 3.1.11.2 Q91XB0 25848017 TLPHGHMQTLIFLNLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGLSKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASRKSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYGT 4yoc A 2.92 BS01 ZN A 1 C1476 C1478 C1485 H1502 C758 C760 C767 H784 2.1.1.37 P26358 25960197 PTKATTTKLVYQIFDTFFADEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLEPVDEDLYPEHYRKYSDYNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKA 4yoc A 2.92 BS02 ZN A 2 H793 C820 C893 C896 H111 C138 C205 C208 2.1.1.37 P26358 25960197 PTKATTTKLVYQIFDTFFADEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLEPVDEDLYPEHYRKYSDYNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKA 4yoq A 2.21 BS01 NUC B 1 Q48 T49 R50 G85 L86 G87 Y88 Y89 K163 C164 R201 G260 L261 L262 H305 A306 F307 S308 H309 P345 V346 Q40 T41 R42 G77 L78 G79 Y80 Y81 K155 C156 R193 G248 L249 L250 H289 A290 F291 S292 H293 P329 V330 3.2.2.- P83847 PAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4yoq A 2.21 BS02 NUC C 1 Q47 Q48 R50 K121 G122 V123 G124 P125 Y126 T127 D144 G145 M148 R149 I161 K163 C164 R167 P200 K228 Q39 Q40 R42 K113 G114 V115 G116 P117 Y118 T119 D136 G137 M140 R141 I153 K155 C156 R159 P192 K220 3.2.2.- P83847 PAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4yoq A 2.21 BS03 SF4 A 1 R153 L154 V197 C198 C205 C208 Q211 C214 A222 R145 L146 V189 C190 C197 C200 Q203 C206 A214 3.2.2.- P83847 PAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4yos A 2.30 BS01 III E 1 Y849 K853 F861 R869 S876 Y879 R880 I931 Y934 N935 Y271 K275 F283 R291 S298 Y301 R302 I315 Y318 N319 L5LUA8 25917549 EFTQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSEERGDLIKFYNTIYVGRVKSFALKYDPLSPFP 4yph A 2.32 BS01 NUC B 1 Q48 T49 R50 G85 L86 G87 Y88 Y89 R91 K235 G260 L261 L262 H305 A306 F307 S308 H309 P345 V346 Q40 T41 R42 G77 L78 G79 Y80 Y81 R83 K223 G248 L249 L250 H289 A290 F291 S292 H293 P329 V330 3.2.2.- P83847 PAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4yph A 2.32 BS02 NUC C 1 Q48 R50 K121 G122 V123 G124 P125 Y126 T127 D144 G145 M148 R149 I161 K163 C164 R167 P200 K228 Q40 R42 K113 G114 V115 G116 P117 Y118 T119 D136 G137 M140 R141 I153 K155 C156 R159 P192 K220 3.2.2.- P83847 PAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4yph A 2.32 BS03 SF4 A 1 R153 L154 C198 P203 C205 C208 Q211 C214 F217 A222 R145 L146 C190 P195 C197 C200 Q203 C206 F209 A214 3.2.2.- P83847 PAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVDGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4ypr A 2.59 BS01 NUC C 1 L28 R31 E43 L46 Q47 Q48 R50 V51 G122 G124 P125 Y126 T127 N144 G145 N146 R149 I191 E192 A195 K228 L23 R26 E38 L41 Q42 Q43 R45 V46 G117 G119 P120 Y121 T122 N139 G140 N141 R144 I186 E187 A190 K223 3.2.2.- P83847 ERFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGEQYGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4ypr A 2.59 BS02 NUC D 1 Q48 T49 R50 E52 T53 G85 L86 G87 Y88 Y89 C164 R201 G260 L261 L262 H305 A306 F307 S308 H309 P345 V346 Q43 T44 R45 E47 T48 G80 L81 G82 Y83 Y84 C159 R196 G255 L256 L257 H300 A301 F302 S303 H304 P340 V341 3.2.2.- P83847 ERFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGEQYGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4ypr A 2.59 BS03 SF4 A 1 R153 L154 C198 P203 C205 C208 Q211 C214 F217 A222 R148 L149 C193 P198 C200 C203 Q206 C209 F212 A217 3.2.2.- P83847 ERFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGEQYGLQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4ypr B 2.59 BS01 NUC E 1 R26 L28 R31 E43 L46 Q47 Q48 R50 V51 G122 G124 P125 Y126 T127 N144 G145 N146 R149 I191 E192 A195 P200 K228 K230 K231 R21 L23 R26 E38 L41 Q42 Q43 R45 V46 G117 G119 P120 Y121 T122 N139 G140 N141 R144 I186 E187 A190 P195 K223 K225 K226 3.2.2.- P83847 ERFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4ypr B 2.59 BS02 NUC F 1 Q48 T49 R50 E52 T53 G85 L86 G87 Y88 Y89 C164 R201 G260 L261 L262 H305 A306 F307 S308 H309 P345 V346 Q43 T44 R45 E47 T48 G80 L81 G82 Y83 Y84 C159 R196 G255 L256 L257 H295 A296 F297 S298 H299 P335 V336 3.2.2.- P83847 ERFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4ypr B 2.59 BS03 SF4 B 1 R153 L154 C198 C205 C208 V210 Q211 C214 F217 A222 R148 L149 C193 C200 C203 V205 Q206 C209 F212 A217 3.2.2.- P83847 ERFPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKMKKTAVKQVPLAVAVLADDEGRVLIRKRDSTGLLANLWEFPSCETDGADGKEKLEQMVGQVELTEPIVSFEHAFSHLVWQLTVFPGRLVHGGPVEEPYRLAPEDELKAYAFPVSHQRVWREYKEWAS 4yta A 1.20 BS01 CA A 1 E70 N72 V75 V76 E80 E52 N54 V57 V58 E62 3.4.21.4 P00760 22751665 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 4yxr A 2.00 BS01 III I 1 S53 K83 E127 F129 S130 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 L205 E230 G234 Y235 P236 F239 A240 D241 I246 Y247 D328 Y330 S39 K69 E113 F115 S116 R119 K154 P155 E156 F173 L184 C185 G186 T187 P188 E189 L191 E216 G220 Y221 P222 F225 A226 D227 I232 Y233 D314 Y316 2.7.11.11 P00517 25877959 VKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKDGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4yxr A 2.00 BS02 0RW A 1 L49 V57 A70 M120 E121 Y122 V123 L173 T183 F327 L35 V43 A56 M106 E107 Y108 V109 L159 T169 F313 2.7.11.11 P00517 25877959 VKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKDGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4yzi A 2.50 BS01 RET A 1 W163 C167 G198 A202 F217 G220 L221 W262 F265 P266 S295 K296 W117 C121 G152 A156 F171 G174 L175 W216 F219 P220 S249 K250 Q8RUT8 25975962 PDYVFHRAHERMLFQTSYTLENNGSVICIPNNGQCFCLAWLKSNGTNAEKLAANILQWITFALSALCLMFYCGWEEIYVATIEMIKFIIEYFHEFDEPAVIYSSNGNKTVWLRYAEWLLTCPVILIHLSNLTGLANDYNKRTMGLLVSDIGGIVWATTAALSKGYVRVIFFLMGLCYGIYTFFNAAKVYIEAYHTVPKGRCRQVVTGMAWLFFVSWGMFPILFILGPEGFGVLSVYGSTVGHTIIDLMSKNCWGLLGHYLRVLIHEHILIHGDIRKTTKIEVETLVEDE 4yzi A 2.50 BS02 ZN A 1 D40 H44 H47 D142 D2 H6 H9 D96 Q8RUT8 25975962 PDYVFHRAHERMLFQTSYTLENNGSVICIPNNGQCFCLAWLKSNGTNAEKLAANILQWITFALSALCLMFYCGWEEIYVATIEMIKFIIEYFHEFDEPAVIYSSNGNKTVWLRYAEWLLTCPVILIHLSNLTGLANDYNKRTMGLLVSDIGGIVWATTAALSKGYVRVIFFLMGLCYGIYTFFNAAKVYIEAYHTVPKGRCRQVVTGMAWLFFVSWGMFPILFILGPEGFGVLSVYGSTVGHTIIDLMSKNCWGLLGHYLRVLIHEHILIHGDIRKTTKIEVETLVEDE 4z1l G 3.00 BS01 MG G 1 T8 Y119 R122 A123 M125 T7 Y118 R121 A122 M124 3.4.25.1 P21243 25973989 GYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIAEQ 4z1l H 3.00 BS01 4KF H 1 T1 R19 S20 K33 G45 A46 G47 A49 G128 S129 T1 R19 S20 K33 G45 A46 G47 A49 G128 S129 3.4.25.1 P25043 25973989 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 4z1l I 3.00 BS01 MG I 1 A174 D177 S180 A174 D177 S180 3.4.25.1 P25451 25973989 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 4z1l K 3.00 BS01 4KF K 1 T1 R19 K33 M45 A46 G47 G130 S131 T1 R19 K33 M45 A46 G47 G130 S131 3.4.25.1 P30656 25973989 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4z1l K 3.00 BS02 MG K 1 A165 H166 D168 A169 S171 A165 H166 D168 A169 S171 3.4.25.1 P30656 25973989 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4z1l N 3.00 BS01 4KF N 1 T1 R19 K33 R45 S46 G47 S129 T1 R19 K33 R45 S46 G47 S129 3.4.25.1 P38624 25973989 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL 4z1l N 3.00 BS02 MG N 1 R19 I163 D166 S169 R19 I163 D166 S169 3.4.25.1 P38624 25973989 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL 4z1l V 3.00 BS01 MG L 1 I163 D166 L167 S169 I163 D166 L167 S169 3.4.25.1 P25043 25973989 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 4z1l V 3.00 BS02 4KF V 1 T1 R19 S20 K33 G45 A46 G47 A49 S129 T1 R19 S20 K33 G45 A46 G47 A49 S129 3.4.25.1 P25043 25973989 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 4z1l W 3.00 BS01 MG W 1 A174 D177 S180 A174 D177 S180 3.4.25.1 P25451 25973989 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 4z1l Y 3.00 BS01 MG I 2 R19 A165 D168 A169 S171 R19 A165 D168 A169 S171 3.4.25.1 P30656 25973989 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4z1l Y 3.00 BS02 4KF Y 1 T1 R19 A20 K33 M45 A46 G47 G130 S131 T1 R19 A20 K33 M45 A46 G47 G130 S131 3.4.25.1 P30656 25973989 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4z1l Z 3.00 BS01 MG Z 1 T192 H195 I196 V198 T192 H195 I196 V198 3.4.25.1 P23724 25973989 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 4z1l b 3.00 BS01 4KF b 1 T1 R19 T20 K33 R45 S46 G47 S129 T1 R19 T20 K33 R45 S46 G47 S129 3.4.25.1 P38624 25973989 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL 4z46 A 1.85 BS01 1PT A 1 D119 Q121 D119 Q121 3.2.1.17 P00698 25974859 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4z46 A 1.85 BS02 CPT A 1 H15 V92 N93 H15 V92 N93 3.2.1.17 P00698 25974859 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4z4r A 1.80 BS01 FUL A 1 E359 W381 K449 E135 W157 K225 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4r A 1.80 BS02 FUL A 2 A354 N355 R356 D385 A130 N131 R132 D161 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4r A 1.80 BS03 FUL B 1 G450 G451 Y452 G226 G227 Y228 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4r B 1.80 BS01 FUL A 3 G450 G451 Y452 G227 G228 Y229 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4r B 1.80 BS02 FUL B 2 E359 W381 K449 E136 W158 K226 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4r B 1.80 BS03 FUL B 1 A354 N355 R356 D385 A131 N132 R133 D162 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4s A 1.80 BS01 FUL A 1 A354 N355 R356 D385 A130 N131 R132 D161 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4s A 1.80 BS02 FUL A 2 E359 W381 K449 E135 W157 K225 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4s A 1.80 BS03 FUL B 1 G450 G451 Y452 G226 G227 Y228 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4s B 1.80 BS01 FUL A 1 G450 G451 Y452 G224 G225 Y226 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4s B 1.80 BS02 FUL B 2 E359 W381 K449 E133 W155 K223 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4s B 1.80 BS03 FUL B 1 A354 N355 R356 D385 A128 N129 R130 D159 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4t A 1.80 BS01 FUL A 1 E359 W381 K449 E132 W154 K222 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4t A 1.80 BS02 FUL A 2 A354 N355 R356 D385 A127 N128 R129 D158 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4t A 1.80 BS03 FUL B 1 G450 G451 Y452 G223 G224 Y225 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4t B 1.80 BS01 FUL A 3 G450 G451 Y452 G224 G225 Y226 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4t B 1.80 BS02 FUL B 2 E359 W381 K449 E133 W155 K223 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4t B 1.80 BS03 FUL B 1 A354 N355 R356 D385 A128 N129 R130 D159 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4u B 1.89 BS01 FUL B 1 A354 N355 R356 D385 A126 N127 R128 D157 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4v A 1.80 BS01 FUL A 1 A354 N355 R356 D385 A127 N128 R129 D158 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4v B 1.80 BS01 FUL A 1 G450 G451 Y452 G220 G221 Y222 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4w A 1.80 BS01 FUL A 1 A354 N355 R356 D385 A130 N131 R132 D161 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4w B 1.80 BS01 FUL A 1 G450 G451 Y452 G220 G221 Y222 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4y A 1.80 BS01 FUC A 1 A354 N355 R356 D385 A131 N132 R133 D162 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4y A 1.80 BS02 GLA A 1 H358 D385 H135 D162 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4y B 1.80 BS01 FUC A 1 G450 G451 Y452 G219 G220 Y221 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4z A 1.80 BS01 FUC A 1 A354 N355 R356 D385 A131 N132 R133 D162 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4z A 1.80 BS02 GLA A 1 H358 D385 H135 D162 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4z A 1.80 BS03 FUC B 1 G450 G451 Y452 G227 G228 Y229 Q5F4T5 SKPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTVPGEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4z B 1.80 BS01 FUC A 1 G450 G451 Y452 G221 G222 Y223 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4z B 1.80 BS02 FUC B 1 A354 N355 R356 D385 A125 N126 R127 D156 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z4z B 1.80 BS03 GLA B 1 H358 D385 H129 D156 Q5F4T5 KPFTLPILTLGELTNSRFPLPIDVLYTNPNESAIVQCQNGRCTLDGELQGTTQLLPTGICAFRGKVTQQVQDEHRGTHWNMTVTNLNGTPFDPTEDVPAPLGTPDFSGQIYGVISQRNTNTNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSSGQPTKFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKGGYGNPAIDCLMPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVARNSAGPVVAPTNGYFRFDSWVNQFYTLAPM 4z7h A 2.90 BS01 4L5 A 1 L577 G578 V586 A597 K599 E612 I626 I642 E643 C645 T648 E651 H692 L695 D711 L16 G17 V25 A36 K38 E51 I65 I81 E82 C84 T87 E90 H131 L134 D150 2.7.11.1,3.1.26.- O75460 25968568 SVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSPGTEGWIAPEMLSNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFH 4z7h B 2.90 BS01 4L5 B 1 L577 G578 V586 A597 K599 I642 E643 C645 T648 E651 H692 N693 L695 S710 D711 L16 G17 V25 A36 K38 I81 E82 C84 T87 E90 H131 N132 L134 S149 D150 2.7.11.1,3.1.26.- O75460 25968568 SVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHVPGTEGWIAPEMLSPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYF 4zee A 1.95 BS01 CPT A 1 H15 N93 H15 N93 3.2.1.17 P00698 25974859 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4zej A 1.79 BS01 ZN A 1 D81 C158 H200 D80 C157 H199 D5JGF6 DEVPELRIEKVKENIFLHTSYSRVNGFGLVSSNGLVVIDKGNAFIVDTPWSDRDTETLVHWIRKNGYELLGSVSTHWHEDRTAGIKWLNDQSISTYATTSTNHLLKENKKEPAKYTLKGNESTLVDGLIEVFYPGGGHTIDNVVVWLPKSKILFGGCFVRSLDSEGLGYTGEAHIDQWSRSAQNALSRYSEAQIVIPGHGKIGDIALLKHTKSLAETAS 4zej A 1.79 BS02 ZN A 2 H77 H79 H139 H76 H78 H138 D5JGF6 DEVPELRIEKVKENIFLHTSYSRVNGFGLVSSNGLVVIDKGNAFIVDTPWSDRDTETLVHWIRKNGYELLGSVSTHWHEDRTAGIKWLNDQSISTYATTSTNHLLKENKKEPAKYTLKGNESTLVDGLIEVFYPGGGHTIDNVVVWLPKSKILFGGCFVRSLDSEGLGYTGEAHIDQWSRSAQNALSRYSEAQIVIPGHGKIGDIALLKHTKSLAETAS 4zej B 1.79 BS01 ZN B 1 H77 H79 H139 H76 H78 H138 D5JGF6 DEVPELRIEKVKENIFLHTSYSRVNGFGLVSSNGLVVIDKGNAFIVDTPWSDRDTETLVHWIRKNGYELLGSVSTHWHEDRTAGIKWLNDQSISTYATTSTNHLLKENKKEPAKYTLKGNESTLVDGLIEVFYPGGGHTIDNVVVWLPKSKILFGGCFVRSLDSEGLGYTGEAHIDQWSRSAQNALSRYSEAQIVIPGHGKIGDIALLKHTKSLAETAS 4zej B 1.79 BS02 ZN B 2 D81 C158 H200 D80 C157 H199 D5JGF6 DEVPELRIEKVKENIFLHTSYSRVNGFGLVSSNGLVVIDKGNAFIVDTPWSDRDTETLVHWIRKNGYELLGSVSTHWHEDRTAGIKWLNDQSISTYATTSTNHLLKENKKEPAKYTLKGNESTLVDGLIEVFYPGGGHTIDNVVVWLPKSKILFGGCFVRSLDSEGLGYTGEAHIDQWSRSAQNALSRYSEAQIVIPGHGKIGDIALLKHTKSLAETAS 4zes A 1.65 BS01 MMA A 1 E172 N174 E178 N194 D195 E106 N108 E112 N128 D129 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zes A 1.65 BS02 CA A 1 E172 N174 E178 N194 D195 E106 N108 E112 N128 D129 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zes B 1.65 BS01 MMA B 1 E172 N174 E178 R186 N194 D195 E106 N108 E112 R120 N128 D129 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zes B 1.65 BS02 CA B 1 E172 N174 E178 N194 D195 E106 N108 E112 N128 D129 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zet A 2.90 BS01 GAL A 1 N137 S139 V200 Q202 N71 S73 V134 Q136 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zet A 2.90 BS02 NAG A 1 S139 N184 R186 N194 I196 S73 N118 R120 N128 I130 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zet A 2.90 BS03 CA A 1 E172 N174 E178 N194 D195 E106 N108 E112 N128 D129 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zet B 2.90 BS01 GAL B 1 M101 N137 S139 V200 Q202 M35 N71 S73 V134 Q136 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zet B 2.90 BS02 NAG B 1 N184 R186 N194 I196 N118 R120 N128 I130 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zet B 2.90 BS03 CA B 1 E172 N174 E178 N194 D195 E106 N108 E112 N128 D129 Q8WTT0 ALTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI 4zgl B 2.95 BS01 AMP B 1 V3 F4 F26 D28 I29 N30 N82 G88 Q89 E90 V91 H95 H97 V3 F4 F26 D28 I29 N30 N82 G88 Q89 E90 V91 H95 H97 P64382 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSG 4zgl C 2.95 BS01 AMP C 1 V3 F4 F26 Y27 D28 I29 N30 N82 Q89 E90 V91 H95 H97 V3 F4 F26 Y27 D28 I29 N30 N82 Q89 E90 V91 H95 H97 P64382 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSG 4zgl F 2.95 BS01 AMP F 1 V3 F4 F26 Y27 D28 I29 L38 N82 G88 Q89 E90 V91 H95 H97 V3 F4 F26 Y27 D28 I29 L38 N82 G88 Q89 E90 V91 H95 H97 P64382 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGD 4zgl H 2.95 BS01 AMP H 1 V3 F4 F26 Y27 D28 I29 N30 L38 N82 G88 Q89 E90 V91 H95 H97 V3 F4 F26 Y27 D28 I29 N30 L38 N82 G88 Q89 E90 V91 H95 H97 P64382 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSG 4zgl I 2.95 BS01 AMP I 1 V3 F26 D28 I29 N30 L38 N82 G88 Q89 E90 V91 H95 H97 V3 F26 D28 I29 N30 L38 N82 G88 Q89 E90 V91 H95 H97 P64382 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGD 4zhk A 2.09 BS01 FE2 A 1 H180 H241 H313 H527 H162 H218 H290 H504 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4zhk A 2.09 BS02 A8V A 1 F61 F103 V134 T147 E148 N175 N194 Y239 H241 I259 Y275 Y338 F60 F102 V116 T129 E130 N157 N176 Y216 H218 I236 Y252 Y315 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4zhk A 2.09 BS03 A9V A 1 L60 F61 H241 F312 H313 Y338 L341 E417 F418 F442 P444 V524 H527 L59 F60 H218 F289 H290 Y315 L318 E394 F395 F419 P421 V501 H504 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4zhk B 2.09 BS01 FE2 B 1 H180 H241 H313 H527 H162 H218 H290 H504 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4zhk B 2.09 BS02 A8V B 1 F61 F103 T129 V134 T147 E148 T149 N175 N194 H241 I259 Y275 Y338 F60 F102 T111 V116 T129 E130 T131 N157 N176 H218 I236 Y252 Y315 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4zhk B 2.09 BS03 A9V B 1 L60 F61 H241 F312 H313 Y338 L341 E417 F418 F442 P444 V524 H527 L59 F60 H218 F289 H290 Y315 L318 E394 F395 F419 P421 V501 H504 3.1.1.64 Q28175 SSQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHLFDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPEVTDNALVNIYPVGEDYYACTETNFITKVNPETLETIKQVDLCNYVSVNGATAHPHIENDGTVYNIGNCFIAYNIVKIPPLQADKEDPISKSEIVVQFPCSDRFKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADKKRKKYINNKYRTSPFNLFHHINTYEDHEFLIVDLCCWKGFEFVYNYLYLANLRENWEEVKKNARKAPQPEVRRYVLPLNIDKADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPRQAFEFPQINYQKYGGKPYTYAYGLGLNHFVPDRLCKLNVKTKETWVWQEPDSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKKS 4zq3 A 1.90 BS01 CA A 1 D21 R35 D40 T41 E43 D15 R29 D34 T35 E37 3.1.31.1 P00644 LHKEPATLIKAIDGDTVKLMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYTYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLRKAEAQAKKEKLNIWS 4zq3 A 1.90 BS02 THP A 1 R35 D40 K84 Y85 R87 L89 Y113 Y115 R29 D34 K72 Y73 R75 L77 Y101 Y103 3.1.31.1 P00644 LHKEPATLIKAIDGDTVKLMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYTYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLRKAEAQAKKEKLNIWS 4zrb A 2.20 BS01 COA E 1 A42 G44 Y75 L76 K77 A78 A39 G41 Y72 L73 K74 A75 Q97NZ8 FHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHGGYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMDVDITNQEGRNVCKATFTMFVTGQR 4zrb B 2.20 BS01 COA F 1 V67 T68 L69 F121 V64 T65 L66 F118 Q97NZ8 FHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHGGYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMDVDITNQEGRNVCKATFTMFVTGQR 4zrb C 2.20 BS01 COA F 1 A42 G44 Y75 L76 K77 A78 A39 G41 Y72 L73 K74 A75 Q97NZ8 FHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHGGYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMDVDITNQEGRNVCKATFTMFVTGQR 4zrb D 2.20 BS01 COA E 1 V67 T68 L69 F121 V64 T65 L66 F118 Q97NZ8 FHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHGGYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMDVDITNQEGRNVCKATFTMFVTGQRS 4zrb E 2.20 BS01 COA E 1 H93 G95 R96 T97 T98 H96 G98 R99 T100 T101 Q97NZ8 SNAMKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHGGYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMDVDITNQEGRNVCKATFTMFVTGQ 4zrb G 2.20 BS01 COA G 1 H93 G95 R96 T97 T98 H94 G96 R97 T98 T99 Q97NZ8 AMKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHGGYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMDVDITNQEGRNVCKATFTMFVTGQRS 4zrb H 2.20 BS01 COA H 1 H93 G95 R96 T97 T98 H93 G95 R96 T97 T98 Q97NZ8 MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHGGYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMDVDITNQEGRNVCKATFTMFVTGQR 4zrb F 2.20 BS01 COA F 1 H93 G95 R96 T97 T98 H94 G96 R97 T98 T99 Q97NZ8 AMKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHGGYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMDVDITNQEGRNVCKATFTMFVTGQ 4zru A 1.90 BS01 TI9 A 1 Y89 S142 W143 C188 Y192 Y97 S150 W151 C195 Y199 P58154 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru A 1.90 BS02 TI9 E 1 W53 R104 L112 M114 W61 R112 L120 M122 P58154 DYKDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru B 1.90 BS01 TI9 A 1 W53 R104 L112 M114 W57 R108 L116 M118 P58154 DDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4zru B 1.90 BS02 TI9 B 1 Y89 W143 V183 Y185 C188 Y192 Y93 W147 V187 Y189 C192 Y196 P58154 DDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4zru C 1.90 BS01 TI9 B 1 R104 L112 M114 R103 L111 M113 P58154 DRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru C 1.90 BS02 TI9 C 1 Y89 S142 W143 C188 Y192 Y88 S141 W142 C187 Y191 P58154 DRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru D 1.90 BS01 TI9 C 1 W53 R104 L112 M114 W54 R105 L113 M115 P58154 KLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4zru D 1.90 BS02 TI9 D 1 Y89 S142 W143 Y185 C188 Y192 Y90 S143 W144 Y186 C189 Y193 P58154 KLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4zru E 1.90 BS01 TI9 D 1 W53 R104 L112 M114 W53 R104 L112 M114 P58154 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru E 1.90 BS02 TI9 E 1 Y89 S142 W143 Y185 C188 Y192 Y89 S142 W143 Y185 C188 Y192 P58154 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru F 1.90 BS01 TI9 F 1 Y89 S142 W143 C188 Y192 Y95 S148 W149 C194 Y198 P58154 KDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4zru F 1.90 BS02 TI9 J 1 W53 R104 L112 M114 W59 R110 L118 M120 P58154 KDDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 4zru G 1.90 BS01 TI9 F 1 W53 R104 L112 M114 W56 R107 L115 M117 P58154 DDDKLDRADILYNIRQTSRPDVIPTQRRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru G 1.90 BS02 TI9 G 1 Y89 S142 W143 Y185 C188 Y192 Y92 S145 W146 Y182 C185 Y189 P58154 DDDKLDRADILYNIRQTSRPDVIPTQRRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru H 1.90 BS01 TI9 G 1 W53 R104 L112 M114 W54 R105 L113 M115 P58154 KLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRK 4zru H 1.90 BS02 TI9 H 1 Y89 S142 W143 Y185 C188 Y192 Y90 S143 W144 Y185 C188 Y192 P58154 KLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRK 4zru I 1.90 BS01 TI9 H 1 W53 R104 L112 M114 W52 R103 L111 M113 P58154 KLDRADILYNIRQTSRPDVIPTDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru I 1.90 BS02 TI9 I 1 Y89 S142 W143 Y185 C188 Y192 Y88 S141 W142 Y184 C187 Y191 P58154 KLDRADILYNIRQTSRPDVIPTDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru J 1.90 BS01 TI9 I 1 W53 R104 L112 M114 W55 R106 L114 M116 P58154 DKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPNSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zru J 1.90 BS02 TI9 J 1 Y89 S142 W143 Y185 C188 Y192 Y91 S144 W145 Y184 C187 Y191 P58154 DKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPNSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 4zui A 1.70 BS01 THP A 1 R35 D40 K84 Y85 R87 L89 Y113 Y115 R29 D34 K72 Y73 R75 L77 Y101 Y103 3.1.31.1 P00644 LHKEPATLIKAIDGDTHKLMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLRKAEAQAKKEKLNIWS 4zui A 1.70 BS02 CA A 1 D21 D40 T41 E43 D15 D34 T35 E37 3.1.31.1 P00644 LHKEPATLIKAIDGDTHKLMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLRKAEAQAKKEKLNIWS 4zuj A 1.72 BS01 THP A 1 R35 D40 K84 Y85 R87 L89 Y113 Y115 R29 D34 K72 Y73 R75 L77 Y101 Y103 3.1.31.1 P00644 LHKEPATLIKAIDGDTVKLMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAHIYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLRKAEAQAKKEKLNIWS 4zuj A 1.72 BS02 CA A 1 D21 D40 T41 E43 D15 D34 T35 E37 3.1.31.1 P00644 LHKEPATLIKAIDGDTVKLMYKGQPMTFRLLLVDTPEFNEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAHIYADGKMVNEALVRQGLAKVAYVYKGNNTHEQLLRKAEAQAKKEKLNIWS 4zwl A 2.60 BS01 NAD A 1 I153 T154 P155 W156 N157 Q162 K180 S182 E183 G213 G217 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 L418 W456 I156 T157 P158 W159 N160 Q165 K183 S185 E186 G216 G220 F234 T235 G236 G237 T240 H243 I244 E258 L259 G260 C292 E393 F395 L421 W459 1.2.1.8 Q5HCU0 FQGMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFFPLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4zwl B 2.60 BS01 NAD B 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 W456 I156 T157 P158 W159 N160 K183 S185 E186 G216 G220 F234 T235 G236 G237 T240 H243 I244 E258 L259 G260 C292 E393 F395 W459 1.2.1.8 Q5HCU0 FQGMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFFPLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4zwl C 2.60 BS01 NAD C 1 I153 T154 P155 W156 N157 K180 P181 S182 E183 G213 G217 F231 T232 G233 G234 T237 H240 E255 L256 G257 C289 E390 F392 L418 W456 I156 T157 P158 W159 N160 K183 P184 S185 E186 G216 G220 F234 T235 G236 G237 T240 H243 E258 L259 G260 C292 E393 F395 L421 W459 1.2.1.8 Q5HCU0 FQGMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFFPLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4zwl D 2.60 BS01 NAD D 1 I153 T154 P155 W156 N157 Q162 K180 S182 E183 G213 G217 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 W456 I155 T156 P157 W158 N159 Q164 K182 S184 E185 G215 G219 F233 T234 G235 G236 T239 H242 I243 E257 L258 G259 C291 E392 F394 W458 1.2.1.8 Q5HCU0 QGMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFFPLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4zwl E 2.60 BS01 NAD E 1 I153 T154 P155 W156 N157 Q162 K180 S182 E183 G213 G217 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 L418 W456 I153 T154 P155 W156 N157 Q162 K180 S182 E183 G213 G217 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 L418 W456 1.2.1.8 Q5HCU0 MELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFFPLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4zwl F 2.60 BS01 NAD F 1 I153 T154 P155 W156 K180 S182 E183 G213 G217 D218 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 W456 I153 T154 P155 W156 K180 S182 E183 G213 G217 D218 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 W456 1.2.1.8 Q5HCU0 MELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFFPLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4zwl G 2.60 BS01 NAD G 1 I153 T154 P155 W156 Q162 K180 S182 E183 G213 G217 D218 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 L418 W456 I153 T154 P155 W156 Q162 K180 S182 E183 G213 G217 D218 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 L418 W456 1.2.1.8 Q5HCU0 MELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFFPLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4zwl H 2.60 BS01 NAD H 1 I153 T154 P155 W156 N157 Q162 K180 S182 E183 G213 G217 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 L418 W456 I153 T154 P155 W156 N157 Q162 K180 S182 E183 G213 G217 F231 T232 G233 G234 T237 H240 I241 E255 L256 G257 C289 E390 F392 L418 W456 1.2.1.8 Q5HCU0 MELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFFPLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4zzm A 1.89 BS01 CQ6 A 1 I31 A52 K54 Q105 D106 M108 E109 T110 D111 L156 C166 D167 I21 A42 K44 Q95 D96 M98 E99 T100 D101 L146 C156 D157 2.7.11.24 P28482 25977981 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQ 4zzn A 1.33 BS01 CQ8 A 1 I29 E31 G32 V37 A50 Q103 D104 M106 E107 T108 D109 K112 N152 L154 C164 I21 E23 G24 V29 A42 Q95 D96 M98 E99 T100 D101 K104 N144 L146 C156 2.7.11.24 P28482 25977981 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFDDLPKEKLKELIFEETARFQ 4zzo A 1.63 BS01 CQ3 A 1 I31 E33 V39 A52 Q105 D106 M108 E109 T110 K114 L156 C166 I21 E23 V29 A42 Q95 D96 M98 E99 T100 K104 L146 C156 2.7.11.24 P28482 25977981 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKDDLPKEKLKELIFEETARFQ