2mok A BS01 FMN A 1 S10 D11 T12 G13 N14 T15 P55 T56 W57 Y58 Y59 G60 G89 D90 Y94 Y97 F98 C99 S10 D11 T12 G13 N14 T15 P55 T56 W57 Y58 Y59 G60 G89 D90 Y94 Y97 F98 C99 MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDLEAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDALGTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKWVKQISEELHLDEILNA 3j82 A 7.70 BS01 CA A 1 Q174 E180 E256 Q41 E47 E123 Q8BRU4 CSPCPHNWIQNGKSCYYVFERWEMWNISKKSCLKEGASLFQIDSKEEMEFISSIGKLKGGNKYWVGVFQDGISGSWFWEDGSSPLSDLLPAERQRSAGQICGYLKDSTLISDKCDSWKYFICEKKAFGSCI 3j82 B 7.70 BS01 ADP B 1 G156 D157 G158 K213 G301 G302 T303 M305 Y306 K336 G155 D156 G157 K212 G300 G301 T302 M304 Y305 K335 P60709 DDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 3wv1 A 1.98 BS05 NA A 1 T126 D128 D203 E205 T206 W207 T23 D25 D100 E102 T103 W104 3.4.24.- P45452 25264600 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDP 3wv1 A 1.98 BS06 FMT A 1 A186 H222 E223 H226 H232 A83 H119 E120 H123 H129 3.4.24.- P45452 25264600 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDP 3wv1 A 1.98 BS07 WHH A 1 K140 L185 N215 F217 L218 V219 H222 A238 L239 F241 I243 Y244 T245 Y246 T247 K249 F252 M253 P255 K37 L82 N112 F114 L115 V116 H119 A135 L136 F138 I140 Y141 T142 Y143 T144 K146 F149 M150 P152 3.4.24.- P45452 25264600 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDP 3wv1 B 1.98 BS05 NA B 1 T126 D128 D203 D204 E205 T206 W207 T21 D23 D98 D99 E100 T101 W102 3.4.24.- P45452 25264600 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 3wv1 B 1.98 BS06 FMT B 1 H222 E223 H232 H117 E118 H127 3.4.24.- P45452 25264600 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 3wv1 B 1.98 BS07 WHH B 1 K140 N215 F217 L218 H222 E223 A238 L239 F241 I243 Y244 T245 Y246 T247 K249 H251 F252 M253 P255 K35 N110 F112 L113 H117 E118 A133 L134 F136 I138 Y139 T140 Y141 T142 K144 H146 F147 M148 P150 3.4.24.- P45452 25264600 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 3wv6 A 1.95 BS01 ZN A 1 D100 C102 H188 H320 D96 C98 H149 H281 O00182 GSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQHMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQSFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT 3wv6 A 1.95 BS02 GAL A 1 H61 N63 R65 N75 W82 E85 H57 N59 R61 N71 W78 E81 O00182 GSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQHMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQSFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT 3wv6 A 1.95 BS03 BGC A 1 R65 E85 R87 R61 E81 R83 O00182 GSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQHMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQSFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT 3wv6 B 1.95 BS02 GAL B 1 H61 N63 R65 V73 N75 W82 E85 H57 N59 R61 V69 N71 W78 E81 O00182 GSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQHMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQSFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT 3x21 B 3.00 BS01 FMN A 1 P38 S39 S40 Q142 L145 P38 S39 S40 Q142 L145 1.5.1.34 P38489 25917861 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSLNSQPWHFIVASTEEGKARVAKSAAGNYVFSERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFWADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV 4d0g A 2.50 BS01 GTP A 1 M20 G21 V22 G23 K24 S25 C26 F36 A38 D39 C40 H42 T43 G69 N124 K125 D127 L128 S154 A155 K156 M13 G14 V15 G16 K17 S18 C19 F29 A31 D32 C33 H35 T36 G62 N117 K118 D120 L121 S147 A148 K149 P61106 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGLERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQ 4d0g A 2.50 BS02 MG A 1 S25 T43 S18 T36 P61106 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGLERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQ 4d0r A 2.75 BS02 41I A 1 G96 M103 F149 D150 M155 Y158 G192 P193 M199 W222 G95 M102 F146 D147 M152 Y155 G189 P190 M196 W219 1.3.1.9 P9WGR0 TGLLDGKRILVSGIITDSSIAFHIARVAQEEGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMNPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4d0s A 1.64 BS02 9G4 A 1 G96 F97 M98 M103 F149 D150 M155 Y158 M161 A191 G192 P193 I194 W222 G92 F93 M94 M99 F145 D146 M151 Y154 M157 A187 G188 P189 I190 W209 1.3.1.9 P9WGR0 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4d0s A 1.64 BS03 MG A 1 D223 Q224 A226 D210 Q211 A213 1.3.1.9 P9WGR0 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4noe A 2.20 BS01 NUC F 1 R83 R85 L87 E88 L95 L97 P98 K102 S104 G106 A107 K108 V109 E117 A119 D120 I123 Y125 R79 R81 L83 E84 L91 L93 P94 K98 S100 G102 A103 K104 V105 E113 A115 D116 I119 Y121 Q9RY80 MLQIEFITDLGARVTVNVEHESRLLDVQRHYGRLGWTSGEIPSGGYQFPIENEADFDWSLIGARKWKEELVIHRGHAYRRRELEAVDSRKLKLPAAIKYSRGAKVSDPQHVREKADGDIEYVSLAIFRGGKRQERYAVP 4noe B 2.20 BS01 NUC F 1 R83 R85 L87 L97 P98 K102 S104 G106 A107 K108 E117 A119 I123 Y125 R132 R77 R79 L81 L88 P89 K93 S95 G97 A98 K99 E108 A110 I114 Y116 R123 Q9RY80 MLQIEFITDLGARVTVNVEHESRLLDVQRHYGRLGWTSGEIPSGGYQFPIENEADFDWSLIGARKWELVIHRGHAYRRRELEAVDLKLPAAIKYSRGAKVSDPQHVREKADGDIEYVSLAIFRGGKRQERYAVP 4noe D 2.20 BS01 NUC F 1 R83 R85 L87 L97 P98 K102 S104 G106 A107 K108 V109 E117 A119 D120 I123 Y125 R132 R79 R81 L83 L87 P88 K92 S94 G96 A97 K98 V99 E107 A109 D110 I113 Y115 R122 Q9RY80 FTMLQIEFITDLGARVTVNVEHESRLLDVQRHYGRLGWTSGEIPSGGYQFPIENEADFDWSLIGARKWELVIHRGHAYRRRELEAVLPAAIKYSRGAKVSDPQHVREKADGDIEYVSLAIFRGGKRQERYAVP 4op8 A 1.95 BS01 CA A 1 E36 D37 R60 E12 D13 R36 Q8KMX3 HPETLVKVKDAEDQLGGRVGYIELDLASGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTGSQATMDERNRQIAEIGASLIKHW 4opz A 1.45 BS01 2UL A 1 M68 S69 K72 E103 Y104 S129 N131 E165 N169 K233 S234 G235 A236 S237 E238 R242 M44 S45 K48 E79 Y80 S105 N107 E141 N145 K209 S210 G211 A212 S213 E214 R218 Q8KMX3 HPETLVKVKDAEDQLGGRVGYIELDLASGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTGSQATMDERNRQIAEIGASLIKHW 4oq0 A 1.42 BS01 2UL A 1 M68 S69 K72 E103 Y104 S129 N131 E165 P166 L168 N169 E170 K233 S234 G235 A236 S237 E238 R242 M44 S45 K48 E79 Y80 S105 N107 E141 P142 L144 N145 E146 K209 S210 G211 A212 S213 E214 R218 Q8KMX3 HPETLVKVKDAEDQLGGRVGYIELDLASGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTGSQATMDERNRQIAEIGASLIKHW 4oqg A 2.40 BS01 2UL A 1 M69 S70 K73 Y105 S130 N132 E166 N170 K234 S235 G236 A237 G238 R244 M44 S45 K48 Y80 S105 N107 E141 N145 K209 S210 G211 A212 G213 R218 3.5.2.6 Q79DR3 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 4oqg B 2.40 BS01 2UL B 1 M69 S70 E104 Y105 S130 N132 E166 P167 L169 N170 S235 G236 A237 G238 R244 M44 S45 E79 Y80 S105 N107 E141 P142 L144 N145 S210 G211 A212 G213 R218 3.5.2.6 Q79DR3 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 4oqg D 2.40 BS01 2UL D 1 M69 S70 E104 Y105 S130 N132 E166 N170 S235 G236 A237 E240 R244 M44 S45 E79 Y80 S105 N107 E141 N145 S210 G211 A212 E214 R218 3.5.2.6 Q79DR3 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 4oqg F 2.40 BS01 2UL F 1 M69 S70 S130 N132 E166 N170 V216 K234 S235 G236 A237 R244 M44 S45 S105 N107 E141 N145 V191 K209 S210 G211 A212 R218 3.5.2.6 Q79DR3 HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW 4or9 A 2.23 BS01 FE A 1 D99 H101 D127 D85 H87 D113 3.1.3.16 P16298 PPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMARVFSVLRSFEEAKGLDRINERMPPR 4or9 A 2.23 BS02 ZN A 1 D127 N159 H208 H290 D113 N145 H194 H276 3.1.3.16 P16298 PPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMARVFSVLRSFEEAKGLDRINERMPPR 4ora A 2.75 BS01 ZN A 1 D127 N159 H290 D113 N145 H276 3.1.3.16 P16298 PPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELARYLSVLSFEEAKGLDRINERMPPR 4ora A 2.75 BS02 FE A 1 D99 H101 D127 H290 Y320 E490 D85 H87 D113 H276 Y306 E392 3.1.3.16 P16298 PPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELARYLSVLSFEEAKGLDRINERMPPR 4orb B 3.11 BS04 CA B 4 D30 D32 S34 S36 L37 S38 E41 D26 D28 S30 S32 L33 S34 E37 Q63810 SYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 4orc A 2.70 BS02 FE A 1 D99 H101 D127 H290 D87 H89 D115 H278 3.1.3.16 P16298 PPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELVFSV 4oro A 2.40 BS01 GDP A 1 M319 F327 R334 K341 W359 E363 F406 S431 M433 M4 F12 R19 K26 W44 E48 F91 S116 M118 GSHMKIRQRQRFGRLELKRISGRGFKNDEEILIGNGTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDLIILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSSDLFDQWGYEESPKASELHGINESMNASDYTLKGVVVTKN 4oro D 2.40 BS01 GDP D 1 H318 M319 F327 R334 K341 W359 E363 K378 F406 S431 M433 H3 M4 F12 R19 K26 W44 E48 K63 F91 S116 M118 GSHMKIRQRQRFGRLELKRISGRGFKNDEEILIGNGTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDLIILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSSDLFDQWGYEESPKASELHGINESMNASDYTLKGVVVTKN 4p44 A 1.75 BS04 2F7 A 1 G206 K207 V208 R210 N257 H377 D387 E424 E425 G427 L428 D453 G518 N519 R534 R536 G548 Y549 Y552 H553 K699 Y700 G152 K153 V154 R156 N203 H323 D333 E370 E371 G373 L374 D399 G464 N465 R480 R482 G491 Y492 Y495 H496 K640 Y641 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4p45 A 1.87 BS04 2F9 A 1 K207 R210 N257 H377 D387 E424 E425 G427 L428 D453 R463 G518 N519 R534 R536 G548 Y552 H553 N698 K699 Y700 A701 K153 R156 N203 H323 D333 E370 E371 G373 L374 D399 R409 G464 N465 R480 R482 G490 Y494 H495 N638 K639 Y640 A641 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4p4b A 1.93 BS04 2G2 A 1 R210 Y234 N257 H377 D387 E424 E425 G427 L428 D453 G518 N519 R534 R536 S547 Y549 Y552 H553 K699 Y700 R156 Y180 N203 H323 D333 E370 E371 G373 L374 D399 G464 N465 R480 R482 S493 Y495 Y498 H499 K643 Y644 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4p4d A 1.65 BS04 2GR A 1 R210 N257 H377 D387 E424 E425 G427 L428 D453 R463 G518 N519 R534 Y552 H553 K699 Y700 R156 N203 H323 D333 E370 E371 G373 L374 D399 R409 G464 N465 R480 Y491 H492 K636 Y637 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4p4e A 1.67 BS05 2G4 A 1 R210 N257 H377 D387 E424 E425 G427 L428 D453 E457 G518 N519 K545 G548 Y549 Y552 H553 K699 Y700 R156 N203 H323 D333 E370 E371 G373 L374 D399 E403 G464 N465 K491 G494 Y495 Y498 H499 K643 Y644 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4p4f A 1.86 BS04 2GB A 1 R210 N257 H377 D387 E424 E425 G427 L428 D453 E457 R463 G518 N519 N544 K545 G548 Y549 Y552 H553 K699 Y700 R156 N203 H323 D333 E370 E371 G373 L374 D399 E403 R409 G464 N465 N490 K491 G494 Y495 Y498 H499 K643 Y644 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4p4i A 1.87 BS04 2G5 A 1 R210 N257 H377 D387 E424 E425 G427 L428 D453 G518 N519 R534 R536 Y552 H553 K699 Y700 R156 N203 H323 D333 E370 E371 G373 L374 D399 G464 N465 R480 R482 Y496 H497 K641 Y642 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4pde A 2.80 BS01 GDP A 1 S240 F260 K262 R265 S207 F227 K229 R232 J7QY30 25649206 ITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN 4pen A 2.10 BS01 0GA A 1 P306 H388 T415 L416 Y439 I458 A472 G473 K492 P300 H382 T409 L410 Y433 I452 A466 G467 K486 4.1.3.27 P9WFX2 ADLAATTSREDFRLLAAEHRVVPVTRKVLADSETPLSAYRKLAANRPGTFLLESAENGRSWSRWSFIGAGAPTALTVREGQAVWLGAVPKDAPTGGDPLRALQVTLELLATADPGLPPLSGGMVGFFAYDMVRRLERLPERAVDDLCLPDMLLLLATDVAAVDHHEGTITLIANAVNWNGTDERVDWAYDDAVARLDVMTAALGQPLPSTVATFSRPEPRHRAQRTVEEYGAIVEYLVDQIAAGEAFQVVPSQRFEMDTDVDPIDVYRILRVTNPSPYMYLLQVPNSDGAVDFSIVGSSPEALVTVHEGWATTHPIAGTRWRGRTDDEDVLLEKELLADDKERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHIERYSHVMHLVSTVTGKLGEGRTALDAVTACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRNGTAYVQAGGGVVADSNGSYEYNEARNKARAVLNAIAAAETLAAPGA 4pen A 2.10 BS02 IND A 1 L54 E55 Y284 M285 Y286 V443 Y445 D453 L52 E53 Y278 M279 Y280 V437 Y439 D447 4.1.3.27 P9WFX2 ADLAATTSREDFRLLAAEHRVVPVTRKVLADSETPLSAYRKLAANRPGTFLLESAENGRSWSRWSFIGAGAPTALTVREGQAVWLGAVPKDAPTGGDPLRALQVTLELLATADPGLPPLSGGMVGFFAYDMVRRLERLPERAVDDLCLPDMLLLLATDVAAVDHHEGTITLIANAVNWNGTDERVDWAYDDAVARLDVMTAALGQPLPSTVATFSRPEPRHRAQRTVEEYGAIVEYLVDQIAAGEAFQVVPSQRFEMDTDVDPIDVYRILRVTNPSPYMYLLQVPNSDGAVDFSIVGSSPEALVTVHEGWATTHPIAGTRWRGRTDDEDVLLEKELLADDKERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHIERYSHVMHLVSTVTGKLGEGRTALDAVTACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRNGTAYVQAGGGVVADSNGSYEYNEARNKARAVLNAIAAAETLAAPGA 4pen A 2.10 BS03 PYR A 1 R42 P214 R40 P208 4.1.3.27 P9WFX2 ADLAATTSREDFRLLAAEHRVVPVTRKVLADSETPLSAYRKLAANRPGTFLLESAENGRSWSRWSFIGAGAPTALTVREGQAVWLGAVPKDAPTGGDPLRALQVTLELLATADPGLPPLSGGMVGFFAYDMVRRLERLPERAVDDLCLPDMLLLLATDVAAVDHHEGTITLIANAVNWNGTDERVDWAYDDAVARLDVMTAALGQPLPSTVATFSRPEPRHRAQRTVEEYGAIVEYLVDQIAAGEAFQVVPSQRFEMDTDVDPIDVYRILRVTNPSPYMYLLQVPNSDGAVDFSIVGSSPEALVTVHEGWATTHPIAGTRWRGRTDDEDVLLEKELLADDKERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHIERYSHVMHLVSTVTGKLGEGRTALDAVTACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRNGTAYVQAGGGVVADSNGSYEYNEARNKARAVLNAIAAAETLAAPGA 4phl A 1.95 BS02 PIL A 1 H669 T783 M785 D822 I823 N825 A837 V840 F844 M861 G873 Q874 F877 H83 T197 M199 D236 I237 N239 A251 V254 F258 M275 G287 Q288 F291 Q8WQX9 TAITKVEREAVLVCELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLE 4phl B 1.95 BS02 PIL B 1 H669 M785 D822 I823 N825 W836 A837 V840 F844 M861 G873 Q874 F877 H83 M199 D236 I237 N239 W250 A251 V254 F258 M275 G287 Q288 F291 Q8WQX9 TAITKVEREAVLVCELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR 4q47 A 2.90 BS01 ADP A 1 Y22 A24 F25 R26 Q29 G49 G51 K52 S53 Y18 A20 F21 R22 Q25 G45 G47 K48 S49 Q9RUU2 25243132 PAALHDRALHLLQTIWGYPAFRGVQGEIVQQVAEGGNALVLMPTGGGKSLCYQLPSLLRPGTGIVVSPLIALMKDQVDTLRQNGVRAAFLNSTLLPHEAREVEDALLRGDLDLLYVAPERLLMPRTLDLLERAPVALFAIDEAHCVSQWGHDFRPEYQQLSVLAERFPELPRVALTATADERTRADIKSVLRLEDAPQFVSSFDRPNIQYRVGLKDSPKTQLLHFIREEHPGDAGIVYCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVIVCATVAIDKPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTAWMVYGLSDVVNVRRMLAQSDAPEEVKRVEASKLDALLTYCEAATCRRQVLLHYFGEELSEPCGNCDVCLNPPRVRDLTREAQMALSATIRTGNRFGAAHLTDVLLGRETDKVLAQGHHQLPTFGVGKEHDEKLWRSVLRQLVSLGYLSADDHFGLRATGKSRGILKEGQKLLLREDTLLPGLEHH 4q47 A 2.90 BS02 ZN A 1 C381 C398 C401 C404 C373 C390 C393 C396 Q9RUU2 25243132 PAALHDRALHLLQTIWGYPAFRGVQGEIVQQVAEGGNALVLMPTGGGKSLCYQLPSLLRPGTGIVVSPLIALMKDQVDTLRQNGVRAAFLNSTLLPHEAREVEDALLRGDLDLLYVAPERLLMPRTLDLLERAPVALFAIDEAHCVSQWGHDFRPEYQQLSVLAERFPELPRVALTATADERTRADIKSVLRLEDAPQFVSSFDRPNIQYRVGLKDSPKTQLLHFIREEHPGDAGIVYCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVIVCATVAIDKPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTAWMVYGLSDVVNVRRMLAQSDAPEEVKRVEASKLDALLTYCEAATCRRQVLLHYFGEELSEPCGNCDVCLNPPRVRDLTREAQMALSATIRTGNRFGAAHLTDVLLGRETDKVLAQGHHQLPTFGVGKEHDEKLWRSVLRQLVSLGYLSADDHFGLRATGKSRGILKEGQKLLLREDTLLPGLEHH 4q47 B 2.90 BS01 ADP B 1 Y22 A24 R26 Q29 T48 G49 G51 K52 S53 Y15 A17 R19 Q22 T41 G42 G44 K45 S46 Q9RUU2 25243132 LHDRALHLLQTIWGYPAFRGVQGEIVQQVAEGGNALVLMPTGGGKSLCYQLPSLLRPGTGIVVSPLIALMKDQVDTLRQNGVRAAFLNSTLLPHEAREVEDALLRGDLDLLYVAPERLLMPRTLDLLERAPVALFAIDEAHCVSQWGHDFRPEYQQLSVLAERFPELPRVALTATADERTRADIKSVLRLEDAPQFVSSFDRPNIQYRVGLKDSPKTQLLHFIREEHPGDAGIVYCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVIVCATVADKPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTAWMVYGLSDVVNVRRMLAQSDAPEEVKRVEASKLDALLTYCEAATCRRQVLLHYFGEELSEPCGNCDVCLNPPRVRDLTREAQMALSATIRTGNRFGAAHLTDVLLGRETDKVLAQGHHQLPTFGVGKEHDEKLWRSVLRQLVSLGYLSADDHFGLRATGKSRGILKEGQKLLLREDTL 4q8u A 1.31 BS02 2YW A 1 D102 Y106 D156 C158 I201 Q203 G229 G230 L231 A232 V233 G234 M260 G261 D92 Y96 D142 C144 I187 Q189 G215 G216 L217 A218 V219 G220 M246 G247 2.4.2.29 P28720 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSSRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 4q8v A 1.40 BS02 2YX A 1 D102 Y106 D156 C158 I201 Q203 G229 G230 L231 A232 M260 G261 C281 V282 L283 R286 D92 Y96 D143 C145 I188 Q190 G216 G217 L218 A219 M247 G248 C268 V269 L270 R273 2.4.2.29 P28720 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSHSRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 4qdv A 2.80 BS01 30U A 1 T130 V132 Y143 W175 E185 R188 P204 D205 L206 K207 I219 T81 V83 Y94 W126 E136 R139 P155 D156 L157 K158 I170 3.6.1.59 Q96C86 VRLPFSGFRLQKVLRESARDKIIFLHGKVEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQ 4qdv D 2.80 BS01 30U D 1 T130 V132 Y143 W175 E185 R188 P204 D205 L206 T85 V87 Y98 W130 E140 R143 P159 D160 L161 3.6.1.59 Q96C86 APVRLPFSGFRLQKVLRESARDKIIFLHGKVNEGDGEDAVVILEKTPFQVEQVAQLLPELQLQFSDIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQS 4qeb A 3.21 BS01 31G B 1 H139 K142 Y143 L171 W175 E185 P204 D205 L206 K207 I219 S272 Y273 H90 K93 Y94 L122 W126 E136 P155 D156 L157 K158 I170 S223 Y224 3.6.1.59 Q96C86 VRLPFSGFRLQKVLRESARDKIIFLHGKVEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQ 4qei A 2.88 BS01 NUC C 1 D72 K75 R76 Q82 G88 G89 V90 S91 I280 R290 D545 Q547 R548 L567 S568 N570 S596 S597 S599 I600 G601 R602 Y604 A605 R606 E609 T617 D619 F620 T631 R633 M638 Q640 F672 Q675 K679 D9 K12 R13 Q19 G25 G26 V27 S28 I175 R185 D427 Q429 R430 L449 S450 N452 S478 S479 S481 I482 G483 R484 Y486 A487 R488 E491 T499 D501 F502 T513 R515 M520 Q522 F554 Q557 K561 6.1.1.14 P41250 IVDRAKMGDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGERFRADHLLKAHLQKLQQELADLFVNFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMEDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETGKK 4qei A 2.88 BS02 AMP A 1 R277 E279 I287 V289 F292 M294 E403 I404 G406 S524 G526 R529 R172 E174 I182 V184 F187 M189 E290 I291 G293 S406 G408 R411 6.1.1.14 P41250 IVDRAKMGDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGERFRADHLLKAHLQKLQQELADLFVNFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMEDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETGKK 4rga A 2.10 BS01 3PV A 1 V200 Q201 S202 R237 K239 F240 D243 N244 N289 S291 A292 N341 F343 Q345 V197 Q198 S199 R234 K236 F237 D240 N241 N286 S288 A289 N338 F340 Q342 D3W0F1 25708888 VLKGINFDRSIVTPENEASILDLAMQNRSGVLDGMTIDILNTTSNQLALFHGTAVLQGYGIEITRAAAPDVLVDTTGQSNETMLLCLTIDLNQVNVPSGTVGTNTYAVDYKQIRLEFLDVPTLLKQYWRDHSLHDLIDPRRVISMPLYWITFGQTGTTPKYEQIKSNYIDGGNSGNPAYGIAARCENFNHFINKVAVQSIPINGVANRPVSSTASQLTNYKVWRNPYLCSQDPRDKFAPDNLVIEEDGIYRIDISGSINIANYTFPASGNSWRVGGRYFQIVCARNSSANNLAEFGAEQHLPPSGVWTRRVLVGEYTAGMTEQAFSSVATISLFKGDNFFLQFETGTNTSRDSAYNNGYGTSGTHLRNFSYTLERVGDLNGTAYYDNGTF 4rht A 2.76 BS01 POP A 1 L65 K66 G67 D182 R188 L38 K39 G40 D149 R155 I6YCM5 25915781 DIKSVLLTAEQIQARIAELGEQIGNDYRGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPR 4rht A 2.76 BS02 5GP A 1 V124 D126 K154 F175 V176 D182 V91 D93 K121 F142 V143 D149 I6YCM5 25915781 DIKSVLLTAEQIQARIAELGEQIGNDYRGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPR 4rht A 2.76 BS03 MG A 1 E122 D123 E89 D90 I6YCM5 25915781 DIKSVLLTAEQIQARIAELGEQIGNDYRGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPR 4rht B 2.76 BS02 5GP B 1 K154 F175 V176 L181 D182 K120 F141 V142 L147 D148 I6YCM5 25915781 GDIKSVLLTAEQIQARIAELGEQIGNDYREQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRV 4rht C 2.76 BS01 POP C 1 K66 D182 R188 K39 D147 R153 I6YCM5 25915781 KSVLLTAEQIQARIAELGEQIGNDYRTTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTL 4rht C 2.76 BS02 5GP C 1 V124 V176 L181 D182 V90 V141 L146 D147 I6YCM5 25915781 KSVLLTAEQIQARIAELGEQIGNDYRTTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTL 4rht D 2.76 BS01 POP D 1 K66 G67 D182 R188 K37 G38 D146 R152 I6YCM5 25915781 DIKSVLLTAEQIQARIAELGEQIGNDYQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGSSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDP 4rht D 2.76 BS02 5GP D 1 V124 V176 D182 V91 V140 D146 I6YCM5 25915781 DIKSVLLTAEQIQARIAELGEQIGNDYQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGSSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDP 4rhu A 2.57 BS01 3QE A 1 L65 K66 V124 D126 S127 G128 L129 T130 K154 F175 V176 L181 D182 R188 L49 K50 V102 D104 S105 G106 L107 T108 K132 F153 V154 L159 D160 R166 I6YCM5 25915781 QTAELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRETTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu A 2.57 BS02 MG A 1 V64 E122 D123 V48 E100 D101 I6YCM5 25915781 QTAELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRETTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu B 2.57 BS01 3QE B 1 K66 G67 V124 V125 D126 S127 G128 T130 K154 D174 F175 V176 L181 D182 R188 K51 G52 V102 V103 D104 S105 G106 T108 K132 D150 F151 V152 L157 D158 R164 I6YCM5 25915781 AELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVNVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhu C 2.57 BS01 45T C 1 D123 V124 D126 S127 G128 T130 K154 F175 V176 L181 D182 R188 D99 V100 D102 S103 G104 T106 K130 F151 V152 L157 D158 R164 I6YCM5 25915781 LYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPR 4rhu F 2.57 BS02 MG F 1 D182 R188 D152 R158 I6YCM5 25915781 ELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhx A 2.03 BS01 3QF A 1 V64 K66 G67 V90 V124 D126 S127 G128 L129 T130 K154 D174 F175 V176 L181 D182 R188 V48 K50 G51 V74 V104 D106 S107 G108 L109 T110 K134 D154 F155 V156 L161 D162 R168 A5U8U8 25915781 ELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGSSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVY 4rhx C 2.03 BS01 3QF C 1 V64 L65 K66 G67 V90 V124 D126 S127 G128 L129 T130 K154 D174 F175 V176 L181 D182 R188 V49 L50 K51 G52 V75 V99 D101 S102 G103 L104 T105 K129 D148 F149 V150 L155 D156 R162 A5U8U8 25915781 AELYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHNVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rhx D 2.03 BS01 3QF D 1 V64 L65 K66 G67 V90 D126 S127 G128 T130 K154 F175 V176 L181 D182 R188 V47 L48 K49 G50 V73 D99 S100 G101 T103 K127 F148 V149 L154 D155 R161 A5U8U8 25915781 LYPGDIKSVLLTAEQIQARIAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVY 4rhy A 2.32 BS02 3QG A 1 K66 G67 S92 V124 V125 D126 S127 G128 L129 T130 K154 F175 V176 L181 D182 R188 K45 G46 S71 V95 V96 D97 S98 G99 L100 T101 K125 F146 V147 L152 D153 R159 A5U8U8 25915781 ELYPGDIKSVLLTAEQIQARIAELGEQIGNDYREGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVY 4rhy D 2.32 BS02 3QG D 1 K66 G67 S92 V124 D126 S127 G128 T130 K154 F175 V176 L181 D182 R188 K46 G47 S72 V100 D102 S103 G104 T106 K130 F151 V152 L157 D158 R164 A5U8U8 25915781 LYPGDIKSVLLTAEQIQARIAELGEQIGNDYRATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYGSSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVYQ 4rol A 1.70 BS01 HEM A 1 Y42 F43 H45 F46 H58 K61 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 H58 K61 L83 L86 H87 L91 V93 N97 F98 L101 L136 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4rol A 1.70 BS02 3U7 A 1 V1 L2 K99 K127 S131 V1 L2 K99 K127 S131 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4rol A 1.70 BS03 3U7 C 1 P95 V96 T137 S138 Y140 R141 P95 V96 T137 S138 Y140 R141 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4rol B 1.70 BS01 HEM B 1 L31 F41 F42 H63 K66 V67 A70 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 L31 F41 F42 H63 K66 V67 A70 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 P68871 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 4rol C 1.70 BS01 3U7 A 1 P95 T137 S138 Y140 R141 P95 T137 S138 Y140 R141 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4rol C 1.70 BS02 HEM C 1 M32 T39 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 M32 T39 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4rol C 1.70 BS03 3U7 C 1 V1 L2 K99 K127 A130 S131 V1 L2 K99 K127 A130 S131 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4rol D 1.70 BS01 HEM D 1 F41 F42 H63 K66 V67 A70 F71 H92 L96 V98 N102 F103 L106 L141 F41 F42 H63 K66 V67 A70 F71 H92 L96 V98 N102 F103 L106 L141 P68871 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 4rom A 1.90 BS03 3U8 C 1 T137 R141 T137 R141 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4rom C 1.90 BS01 3U8 A 1 P95 K99 T137 R141 P95 K99 T137 R141 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4rsl A 1.90 BS01 FAD A 1 V13 G14 G16 G17 T18 I19 D41 V42 S47 Q49 S50 A51 K57 I58 G186 T187 F188 A219 A220 G221 W223 L227 W239 C347 C349 D374 G376 H377 S378 F379 K380 V12 G13 G15 G16 T17 I18 D40 V41 S46 Q48 S49 A50 K56 I57 G185 T186 F187 A218 A219 G220 W222 L226 W238 C346 C348 D373 G375 H376 S377 F378 K379 1.5.3.- Q765A9 25849495 AHSRASTKVVVVGGGGTIGSSTALHLIRSGYTPSNITVLDVYKTPSLQSAGHDLNKIMGIRLRNGPDLQLSLESLDMWQNDELFKPFFHQVGMIDCSSSKEGIENLRRKYQTLLDAGIGLEKTNVWLESEDEILAKAPNFTREQVKGWKGLFCTDGGWLAAAKAINAIGIFLQDKGVKFGFGGAGTFQQPLFAADGKTCIGLETTDGTKYFADKVVLAAGAWSPTLVDLEDQCVSKAWVFAHIQLTPKEADAYKNVPVVYDGEYGFFFEPNEYGVIKVCDEFPGFSRFKLHQPYGAASPKMISVPRSHAKHPTDTYPDASEVTIRKAIARFLPEFKDKELFNRTMCWCTDTADANLLICEHPKWKNFILATGDSGHSFKLLPNIGKHVVELLEGSLSQEMAGAWRWRPGGDALRSRRGAPAKDLAEMPGWKHDAHL 4rwf A 1.76 BS01 III B 1 R1097 E1101 E1105 F1111 V2036 T2037 D2070 W2072 D2090 Y2091 F2092 Q2093 D2094 F2095 H2114 S2117 R2119 W2121 T2122 N2128 R415 E419 E423 F429 V462 T463 D496 W498 D516 Y517 F518 Q519 D520 F521 H540 S543 R545 W547 T548 N554 Q16602 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAAEFGGTVKNYETAVQFCWNHYKDQMDPIEKDWCDWAMISRPYSTLRDCLEHFAERFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSIQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNV 4rwf A 1.76 BS02 MAL A 1 D16 K17 W64 A65 D67 R68 E113 E155 P156 Y157 W232 W342 D14 K15 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 Q16602 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAAEFGGTVKNYETAVQFCWNHYKDQMDPIEKDWCDWAMISRPYSTLRDCLEHFAERFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSIQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNV 4rwg A 2.44 BS01 III D 1 Y343 N351 R356 A372 F374 W1084 D2070 G2071 W2072 D2094 H2114 A2116 S2117 R2119 W2121 T2122 Y2124 T2125 N2128 Y341 N349 R354 A370 F372 W433 D497 G498 W499 D521 H541 A543 S544 R546 W548 T549 Y551 T552 N555 Q16602 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAAEFTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVN 4rwg A 2.44 BS02 MAL A 1 N14 D16 K17 W64 A65 D67 R68 E113 E155 P156 Y157 W232 W342 N12 D14 K15 W62 A63 D65 R66 E111 E153 P154 Y155 W230 W340 Q16602 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAAEFTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVN 4rwg B 2.44 BS01 III E 1 Y343 W1084 D2070 G2071 W2072 F2092 Q2093 D2094 H2114 A2116 S2117 R2119 W2121 T2122 T2125 Y341 W425 D489 G490 W491 F511 Q512 D513 H533 A535 S536 R538 W540 T541 T544 Q16602 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAACNYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLHHHHHH 4rwg B 2.44 BS03 MG B 1 Q2059 N2066 Q478 N485 Q16602 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAACNYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLHHHHHH 4rwg C 2.44 BS01 III F 1 Y343 R356 W1084 D2070 G2071 W2072 F2092 D2094 F2095 H2114 S2117 R2119 W2121 T2122 T2125 Y338 R351 W430 D487 G488 W489 F509 D511 F512 H531 S534 R536 W538 T539 T542 Q16602 EGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAAEFTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVTRNKIMTAQYECYQKIMQDPIGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNV 4rwn A 2.00 BS01 NUC B 1 P21 T23 R26 K41 E42 R53 V54 S55 G66 Q157 R198 T202 K205 R209 P21 T23 R26 K41 E42 R53 V54 S55 G66 Q157 R198 T202 K205 R209 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQKI 4rwn A 2.00 BS02 NUC C 1 D12 K13 E16 K30 I33 D34 C37 K41 K56 V57 V58 K59 Q157 R194 T202 K203 T247 D248 D12 K13 E16 K30 I33 D34 C37 K41 K56 V57 V58 K59 Q157 R194 T202 K203 T247 D248 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQKI 4rwn A 2.00 BS03 APC A 1 G61 S62 K65 S73 D74 D76 Q193 K212 Q229 Y230 G61 S62 K65 S73 D74 D76 Q193 K212 Q229 Y230 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQKI 4rwn A 2.00 BS04 APC A 2 D76 R129 A130 D147 L149 S186 T187 T190 Q193 D76 R129 A130 D147 L149 S186 T187 T190 Q193 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQKI 4rwn A 2.00 BS05 MG A 1 D74 D76 D74 D76 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQKI 4rwn A 2.00 BS06 MG A 2 D74 D76 D147 D74 D76 D147 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQKI 4rwo A 2.20 BS01 NUC B 1 L20 P21 T23 R26 K41 E42 R53 V54 S55 G66 R198 N199 T202 K205 L20 P21 T23 R26 K41 E42 R53 V54 S55 G66 R198 N199 T202 K205 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVRPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQ 4rwo A 2.20 BS02 NUC C 1 D12 K13 E16 K30 D34 C37 K41 K56 V57 K59 Q157 T202 K203 T247 D248 D12 K13 E16 K30 D34 C37 K41 K56 V57 K59 Q157 T202 K203 T247 D248 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVRPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQ 4rwp A 2.25 BS01 NUC B 1 P21 T23 R38 K41 E42 Q46 R53 V54 S55 G66 R198 N199 T202 K205 R209 P21 T23 R38 K41 E42 Q46 R53 V54 S55 G66 R198 N199 T202 K205 R209 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTML 4rwp A 2.25 BS02 NUC C 1 D12 K13 E16 K30 D34 C37 K56 V57 K59 Q157 E191 R194 T202 K203 T247 D248 D12 K13 E16 K30 D34 C37 K56 V57 K59 Q157 E191 R194 T202 K203 T247 D248 2.7.7.84 Q29599 25892109 MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKGGSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEVQSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRGKEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAWEQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILDPADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTML 4tor A 1.50 BS02 IW8 A 1 H1184 G1185 S1186 P1187 F1188 A1191 I1192 G1196 F1197 D1198 H1201 I1212 Y1213 Y1224 I1228 H80 G81 S82 P83 F84 A87 I88 G92 F93 D94 H97 I108 Y109 Y120 I124 2.4.2.30 O95271 25939383 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKP 4tor B 1.50 BS02 IW8 B 1 H1184 S1186 P1187 F1188 A1191 I1192 K1195 G1196 F1197 D1198 H1201 I1212 Y1213 I1228 H80 S82 P83 F84 A87 I88 K91 G92 F93 D94 H97 I108 Y109 I124 2.4.2.30 O95271 25939383 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKP 4tor C 1.50 BS02 IW8 C 1 H1184 G1185 S1186 P1187 F1188 A1191 I1192 K1195 G1196 D1198 H1201 I1212 Y1213 Y1224 I1228 H80 G81 S82 P83 F84 A87 I88 K91 G92 D94 H97 I108 Y109 Y120 I124 2.4.2.30 O95271 25939383 GTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKP 4tos A 1.80 BS02 355 A 1 H1184 G1185 S1186 P1187 F1188 A1191 I1192 K1195 G1196 F1197 D1198 H1201 A1202 G1205 M1207 G1211 Y1213 K1220 Y1224 G1227 I1228 H81 G82 S83 P84 F85 A88 I89 K92 G93 F94 D95 H98 A99 G102 M104 G106 Y108 K115 Y119 G122 I123 2.4.2.30 O95271 25939383 SGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKP 4tyb A 2.93 BS01 3B1 A 1 C366 M414 Y415 Y448 C356 M404 Y405 Y438 2.7.7.48 D0PY27 25666181 SMSYTWTGALITPCAAEESKLPNSLLRHHNMVYATTSRSAGLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSKFGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQRVEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEARQAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASAACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVWRHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPSGWFVAGYSGGDIYH 4tyb B 2.93 BS01 3B1 B 1 R200 C366 M414 Y415 Y448 R190 C356 M404 Y405 Y438 2.7.7.48 D0PY27 25666181 SMSYTWTGALITPCAAEESKLPNSLLRHHNMVYATTSRSAGLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSKFGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQRVEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEARQAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASAACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVWRHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPISGWFVAGYSGGDIYH 4tyb C 2.93 BS01 3B1 C 1 F193 R200 C366 M414 Y415 Y448 F183 R190 C356 M404 Y405 Y438 2.7.7.48 D0PY27 25666181 SMSYTWTGALITPCAAEESKLPNSLLRHHNMVYATTSRSAGLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSKFGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQRVEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEARQAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASAACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVWRHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPSGWFVAGYSGGDIYH 4v1f A 1.70 BS01 BQ1 A 1 G62 E65 A66 F69 G62 E65 A66 F69 3.6.3.14 I0RTF3 MELDPNALITAGALIGGGLIMGGGAIGAGIGDGIAGNALISGIARQPEAQGRLFTPFFITVGLVEAAYFINLAFMALFVFATPGLQ 4v1f A 1.70 BS02 BQ1 B 1 A66 A67 I70 A66 A67 I70 3.6.3.14 I0RTF3 MELDPNALITAGALIGGGLIMGGGAIGAGIGDGIAGNALISGIARQPEAQGRLFTPFFITVGLVEAAYFINLAFMALFVFATPGLQ 4v1f B 1.70 BS01 BQ1 B 1 G62 E65 A66 Y68 F69 L72 G61 E64 A65 Y67 F68 L71 3.6.3.14 I0RTF3 ELDPNALITAGALIGGGLIMGGGAIGAGIGDGIAGNALISGIARQPEAQGRLFTPFFITVGLVEAAYFINLAFMALFVFATPGLQ 4wae A 3.32 BS01 ATP A 1 I562 Y598 I610 P612 V613 I688 D689 I227 Y263 I275 P277 V278 I353 D354 2.7.1.67 Q9UBF8 25897704 LLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPEWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMR 4wag A 3.41 BS01 3K7 A 1 I562 K564 E572 Y598 I610 E611 P612 V613 L678 D689 I226 K228 E236 Y262 I274 E275 P276 V277 L342 D353 2.7.1.67 Q9UBF8 25897704 LLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPEWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMR 4wbb B 2.80 BS01 ADP A 1 L49 G52 S53 V57 A70 K72 E121 V123 E127 N171 L173 T183 D184 F327 L36 G39 S40 V44 A57 K59 E108 V110 E114 N158 L160 T170 D171 F314 2.7.11.11 P05132 SVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 4x5s A 1.95 BS01 ZN A 1 H89 H91 H108 H88 H90 H107 4.2.1.1 C1DTU5 25817590 HWSYEGENGPENWAKLNPEYFWCNLKNQSPVDISDNYKVHAKLEKLHINYNKAVNPEIVNNGHTIQVNVLEDFKLNIKGKEYHLKQFHFHAPSEHTVNGKYYPLEMHLVHKDKDGNIAVIGVFFKEGKANPELDKVFKNALKEEGSKVFDGSININALLPPVKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSIMKHNNNRPTQPINSRYILES 4x5s A 1.95 BS02 AZM A 1 Q87 H89 H91 H108 V110 L173 T174 T175 W184 Q86 H88 H90 H107 V109 L172 T173 T174 W183 4.2.1.1 C1DTU5 25817590 HWSYEGENGPENWAKLNPEYFWCNLKNQSPVDISDNYKVHAKLEKLHINYNKAVNPEIVNNGHTIQVNVLEDFKLNIKGKEYHLKQFHFHAPSEHTVNGKYYPLEMHLVHKDKDGNIAVIGVFFKEGKANPELDKVFKNALKEEGSKVFDGSININALLPPVKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSIMKHNNNRPTQPINSRYILES 4xbq A 2.23 BS02 NAG A 1 R53 E72 R74 R51 E70 R72 P47929 25945972 VPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF 4xkb A 1.50 BS01 DE9 A 1 R113 W183 W189 W192 F196 L210 N211 Q212 L213 R105 W175 W181 W184 F188 L202 N203 Q204 L205 P72583 DNLTELSQQLKQLTAIAALAEMGEGGQGILLDYLAKNVPLEKPVLAVGNVYQTLRNLEQETITTQLQRNYPTGIFPLQSAQGIDYLPLQEALGSQDFETADEITRDKLCELAGPGASQRQWLYFTEVEKFPALDLHTINALWWLHSNGNFGFSVQRRLWLASGKEFTKLWPKIGWKSGNVWTRWPKGFTWDLSAPQGHLPLLNQLRGVRVAESLYRHPVWSQYGW 4xkc A 2.00 BS01 MD9 A 1 R113 W183 W189 W192 F196 N211 Q212 L213 R214 R105 W175 W181 W184 F188 N203 Q204 L205 R206 P72583 NLTELSQQLHKQLTAIAALAEMGEGGQGILLDYLAKNVPLEKPVLAVGNVYQTLRNLEQETITTQLQRNYPTGIFPLQSAQGIDYLPLQEALGSQDFETADEITRDKLCELAGPGASQRQWLYFTEVEKFPALDLHTINALWWLHSNGNFGFSVQRRLWLASGKEFTKLWPKIGWKSGNVWTRWPKGFTWDLSAPQGHLPLLNQLRGVRVAESLYRHPVWSQYGW 4xpa A 2.95 BS02 CLR A 2 A74 I78 F350 A354 F357 Y518 W519 A50 I54 F285 A289 F292 Y453 W454 DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRD 4xpa A 2.95 BS03 42J A 1 F43 D46 V120 D121 F319 F325 S421 S422 G425 F19 D22 V96 D97 F254 F260 S356 S357 G360 DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRD 4xpa A 2.95 BS04 N9S A 1 R133 F136 A137 P144 Y219 D238 R109 F112 A113 P120 Y154 D173 DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRD 4xpq A 1.85 BS01 FUL A 1 W330 E366 Y373 R418 D434 W308 E344 Y351 R396 D412 3.2.1.22 25942325 SHAQTANWTEIYPGVWKATVGKPESYDLLKAAGAQPNKDALSKTEKVSFPFANGGVSLEVSGGKTYLRFPLQKEEQLYGFGLNFQTVHQRGKILELHVDHYGGKDSGRTHAPTPFYVSSNGYGVFINSARYIKVWAGTGVRKDSENFPTPKDRNTDKTWSSRPYSDAVEILVPAEGVEVYVFGGPKPIDAVKRYNLLNGGGYLPPRWGLGFTQRVMTRYTDKDVEKEVNDFKEKGYPLDFVGLEPGWQSKAYPGTFSWDKSRYPDPTSFVKKMKDQGIRLNLWINPYISPDAPFYKEIKPYTGSHTVWLGLVPDFTMAEARKPFFNQLLKDQIERGVSGYKIDEVDGYDYYLWPDAAKFPSGLSAEQMRQTYGLLVQRYSAELYKQRNERTFGLVRASNGGGTSFPYVIYNDYYNHQDFITALINSGFAGVLWTPEVRASKSGEEWLRRFQSNVFSPMAMINAWASGTKPWSYPEVEADVKKFALLRMQMMPYWYSAFARYHFEGMPPFRGMGLSKEIKDQYMAGDDLLVAPMFAGEKSRKVVLPKGKWYDFYTGEYAGDGEVLDVTPGLDKIPVYVRDGGIVPMMPALLNSPKSNQKVDLEIRYYGNKPGEFKLYDDDGETFNYEKGDFSWRTIRVEKDKSGKVKGSISAAVKGKVNTVGKVTFTAMTK 4xpq A 1.85 BS02 FUL A 2 S23 S79 E81 Y88 L89 R90 R163 E191 S1 S57 E59 Y66 L67 R68 R141 E169 3.2.1.22 25942325 SHAQTANWTEIYPGVWKATVGKPESYDLLKAAGAQPNKDALSKTEKVSFPFANGGVSLEVSGGKTYLRFPLQKEEQLYGFGLNFQTVHQRGKILELHVDHYGGKDSGRTHAPTPFYVSSNGYGVFINSARYIKVWAGTGVRKDSENFPTPKDRNTDKTWSSRPYSDAVEILVPAEGVEVYVFGGPKPIDAVKRYNLLNGGGYLPPRWGLGFTQRVMTRYTDKDVEKEVNDFKEKGYPLDFVGLEPGWQSKAYPGTFSWDKSRYPDPTSFVKKMKDQGIRLNLWINPYISPDAPFYKEIKPYTGSHTVWLGLVPDFTMAEARKPFFNQLLKDQIERGVSGYKIDEVDGYDYYLWPDAAKFPSGLSAEQMRQTYGLLVQRYSAELYKQRNERTFGLVRASNGGGTSFPYVIYNDYYNHQDFITALINSGFAGVLWTPEVRASKSGEEWLRRFQSNVFSPMAMINAWASGTKPWSYPEVEADVKKFALLRMQMMPYWYSAFARYHFEGMPPFRGMGLSKEIKDQYMAGDDLLVAPMFAGEKSRKVVLPKGKWYDFYTGEYAGDGEVLDVTPGLDKIPVYVRDGGIVPMMPALLNSPKSNQKVDLEIRYYGNKPGEFKLYDDDGETFNYEKGDFSWRTIRVEKDKSGKVKGSISAAVKGKVNTVGKVTFTAMTK 4xpq A 1.85 BS03 FUL A 3 I115 E117 K126 S128 K155 I93 E95 K104 S106 K133 3.2.1.22 25942325 SHAQTANWTEIYPGVWKATVGKPESYDLLKAAGAQPNKDALSKTEKVSFPFANGGVSLEVSGGKTYLRFPLQKEEQLYGFGLNFQTVHQRGKILELHVDHYGGKDSGRTHAPTPFYVSSNGYGVFINSARYIKVWAGTGVRKDSENFPTPKDRNTDKTWSSRPYSDAVEILVPAEGVEVYVFGGPKPIDAVKRYNLLNGGGYLPPRWGLGFTQRVMTRYTDKDVEKEVNDFKEKGYPLDFVGLEPGWQSKAYPGTFSWDKSRYPDPTSFVKKMKDQGIRLNLWINPYISPDAPFYKEIKPYTGSHTVWLGLVPDFTMAEARKPFFNQLLKDQIERGVSGYKIDEVDGYDYYLWPDAAKFPSGLSAEQMRQTYGLLVQRYSAELYKQRNERTFGLVRASNGGGTSFPYVIYNDYYNHQDFITALINSGFAGVLWTPEVRASKSGEEWLRRFQSNVFSPMAMINAWASGTKPWSYPEVEADVKKFALLRMQMMPYWYSAFARYHFEGMPPFRGMGLSKEIKDQYMAGDDLLVAPMFAGEKSRKVVLPKGKWYDFYTGEYAGDGEVLDVTPGLDKIPVYVRDGGIVPMMPALLNSPKSNQKVDLEIRYYGNKPGEFKLYDDDGETFNYEKGDFSWRTIRVEKDKSGKVKGSISAAVKGKVNTVGKVTFTAMTK 4xps A 2.10 BS01 GLA A 1 E266 P267 Y274 W305 K363 E366 R418 Y432 D434 N484 W486 E238 P239 Y246 W277 K335 E338 R390 Y404 D406 N456 W458 3.2.1.22 25942325 NWTEIYPGVWKATVGKPESYDLLKAAGAQPNKDALSKTEKVSFPFANGGVSLEVSGGKTYLRFPLQKEEQLYGFGLNFQTVHQRGKILELHVDHYGGKDSGRTHAPTPFYVSSNGYGVFINSARYIKVWAGTGVRKDSENFPTPKDRNTDKTWSSRPYSDAVEILVPAEGVEVYVFGGPKPIDAVKRYNLLNGGGYLPPRWGLGFTQRVMTRYTDKDVEKEVNDFKEKGYPLDFVGLEPGWQSKAYPGTFSWDKSRYPDPTSFVKKMKDQGIRLNLWINPYISPDAPFYKEIKPYTGSHTVWLGLVPDFTMAEARKPFFNQLLKDQIERGVSGYKIAEVDGYDYYLWPDAAKFPSGLSAEQMRQTYGLLVQRYSAELYKQRNERTFGLVRASNGGGTSFPYVIYNDYYNHQDFITALINSGFAGVLWTPEVRASKSGEEWLRRFQSNVFSPMAMINAWASGTKPWSYPEVEADVKKFALLRMQMMPYWYSAFARYHFEGMPPFRGMGLESKEIKDQYMAGDDLLVAPMFAGEKSRKVVLPKGKWYDFYTGEYAGDGEVLDVTPGLDKIPVYVRDGGIVPMMPALLNSPKSNQKVDLEIRYYGNKPGEFKLYDDDGETFNYEKGDFSWRTIRVEKDKSGKVKGSISAAVKGKVNTVGKVTFTAMTK 4xps A 2.10 BS02 NPO A 1 E366 D434 W486 E338 D406 W458 3.2.1.22 25942325 NWTEIYPGVWKATVGKPESYDLLKAAGAQPNKDALSKTEKVSFPFANGGVSLEVSGGKTYLRFPLQKEEQLYGFGLNFQTVHQRGKILELHVDHYGGKDSGRTHAPTPFYVSSNGYGVFINSARYIKVWAGTGVRKDSENFPTPKDRNTDKTWSSRPYSDAVEILVPAEGVEVYVFGGPKPIDAVKRYNLLNGGGYLPPRWGLGFTQRVMTRYTDKDVEKEVNDFKEKGYPLDFVGLEPGWQSKAYPGTFSWDKSRYPDPTSFVKKMKDQGIRLNLWINPYISPDAPFYKEIKPYTGSHTVWLGLVPDFTMAEARKPFFNQLLKDQIERGVSGYKIAEVDGYDYYLWPDAAKFPSGLSAEQMRQTYGLLVQRYSAELYKQRNERTFGLVRASNGGGTSFPYVIYNDYYNHQDFITALINSGFAGVLWTPEVRASKSGEEWLRRFQSNVFSPMAMINAWASGTKPWSYPEVEADVKKFALLRMQMMPYWYSAFARYHFEGMPPFRGMGLESKEIKDQYMAGDDLLVAPMFAGEKSRKVVLPKGKWYDFYTGEYAGDGEVLDVTPGLDKIPVYVRDGGIVPMMPALLNSPKSNQKVDLEIRYYGNKPGEFKLYDDDGETFNYEKGDFSWRTIRVEKDKSGKVKGSISAAVKGKVNTVGKVTFTAMTK 4xry A 2.50 BS01 HEM A 1 R101 V119 F120 W128 R132 I186 A305 G306 T309 T313 Q364 V374 H376 L399 P435 F436 S437 R441 C443 L444 G445 L448 A449 R68 V86 F87 W95 R99 I153 A272 G273 T276 T280 Q331 V341 H343 L366 P402 F403 S404 R408 C410 L411 G412 L415 A416 1.14.14.1 P10635 25781223 GKLPPGPLPLPGLGNLLHVDTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 4xry A 2.50 BS02 SI5 A 1 F120 A209 L213 E216 Q244 D301 S304 A305 F483 F87 A176 L180 E183 Q211 D268 S271 A272 F450 1.14.14.1 P10635 25781223 GKLPPGPLPLPGLGNLLHVDTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 4xry B 2.50 BS02 SI5 B 1 F120 A209 G212 L213 E216 Q244 D301 S304 A305 F483 L484 F82 A167 G170 L171 E174 Q202 D259 S262 A263 F441 L442 1.14.14.1 P10635 25781223 GKLPPGPLPGNLLHVTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 4xrz A 2.40 BS01 HEM A 1 R101 V119 F120 W128 R132 I186 L302 A305 T309 T313 Q364 I369 V374 H376 L399 P435 F436 S437 R441 C443 L444 G445 L448 A449 R61 V79 F80 W88 R92 I146 L262 A265 T269 T273 Q324 I329 V334 H336 L359 P395 F396 S397 R401 C403 L404 G405 L408 A409 1.14.14.1 P10635 25781223 GKLPPGPLPDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 4xrz A 2.40 BS02 SI6 A 1 F120 A209 G212 L213 E216 Q244 D301 S304 A305 V308 T309 F483 F80 A169 G172 L173 E176 Q204 D261 S264 A265 V268 T269 F443 1.14.14.1 P10635 25781223 GKLPPGPLPDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 4xrz C 2.40 BS05 ZN C 3 H324 H477 H282 H435 1.14.14.1 P10635 25781223 GKLPPGPLPQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 4xtt A 2.71 BS01 2BA A 1 I163 I164 D167 R169 A170 I174 I176 P191 I31 I32 D35 R37 A38 I42 I44 P59 ASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNI 4xtt B 2.71 BS01 2BA A 1 I163 I164 D167 R169 A170 I174 N175 I176 P191 I31 I32 D35 R37 A38 I42 N43 I44 P59 ASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNI 4xyj A 3.10 BS01 ATP A 1 G33 G34 Y64 R97 C98 F101 R102 G127 D128 G129 S130 G133 S173 R219 G21 G22 Y52 R85 C86 F89 R90 G115 D116 G117 S118 G121 S161 R207 2.7.1.11 Q01813 LRKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ 4xyj A 3.10 BS02 MG A 1 D128 D177 R219 D116 D165 R207 2.7.1.11 Q01813 LRKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ 4xyj A 3.10 BS03 MG A 2 S32 G33 G34 M39 G172 S173 S20 G21 G22 M27 G160 S161 2.7.1.11 Q01813 LRKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ 4xyj B 3.10 BS03 MG B 2 S32 G33 G34 G126 G127 G172 S173 S19 G20 G21 G113 G114 G159 S160 2.7.1.11 Q01813 RKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQP 4xyj C 3.10 BS01 ATP C 1 G33 G34 Y64 R97 C98 F101 R102 G126 G127 D128 G129 S130 T132 G133 S173 D175 D177 R219 G20 G21 Y51 R84 C85 F88 R89 G113 G114 D115 G116 S117 T119 G120 S160 D162 D164 R206 2.7.1.11 Q01813 RKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ 4xyj C 3.10 BS03 MG C 2 S32 G34 M39 G126 G127 G172 S173 S19 G21 M26 G113 G114 G159 S160 2.7.1.11 Q01813 RKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ 4xyj E 3.10 BS01 ATP E 1 S32 G33 G34 Y64 R97 C98 F101 R102 G127 D128 G129 S130 G133 S173 D175 R219 S19 G20 G21 Y51 R84 C85 F88 R89 G114 D115 G116 S117 G120 S160 D162 R206 2.7.1.11 Q01813 RKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGRKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ 4xyj E 3.10 BS02 MG E 1 D128 D177 D115 D164 2.7.1.11 Q01813 RKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGRKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ 4xyj F 3.10 BS04 CO F 1 E489 K524 H525 E475 K510 H511 2.7.1.11 Q01813 KFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEAKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ 4xyj G 3.10 BS03 MG G 2 S32 G33 G34 M39 G126 G127 G172 S173 S19 G20 G21 M26 G113 G114 G159 S160 2.7.1.11 Q01813 RKFLEHLSGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQ 4xyj H 3.10 BS02 MG H 1 D128 R219 D108 R199 2.7.1.11 Q01813 SGAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAK 4y03 A 1.94 BS01 SAL A 1 I651 F652 L655 Y664 M672 A703 N707 I32 F33 L36 Y45 M53 A84 N88 Q86U86 SKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGD 4y03 B 1.94 BS01 SAL B 1 I651 F652 L655 Y664 M672 A703 N707 I713 I32 F33 L36 Y45 M53 A84 N88 I94 Q86U86 SKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGD 4y0x A 1.74 BS01 ADP A 1 A158 G160 G161 V179 K181 V211 M232 E233 Y234 V235 N281 I292 D293 A76 G78 G79 V97 K99 V129 M150 E151 Y152 V153 N199 I210 D211 2.7.11.1 P9WI73 25960409 RAPDIDPLEALMTNPVVPESKRFCWNCGRPVGRSDSETKGASEGWCPYCGSPYSFLPQLNPGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQAMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKRSKGQKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTEEQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLAALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAEEMSAQLTGVLREVVAQDT 4y0x A 1.74 BS02 ZN A 1 C106 C109 C128 C131 C24 C27 C46 C49 2.7.11.1 P9WI73 25960409 RAPDIDPLEALMTNPVVPESKRFCWNCGRPVGRSDSETKGASEGWCPYCGSPYSFLPQLNPGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQAMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKRSKGQKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTEEQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLAALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAEEMSAQLTGVLREVVAQDT 4y0x A 1.74 BS03 MG A 1 N281 D293 N199 D211 2.7.11.1 P9WI73 25960409 RAPDIDPLEALMTNPVVPESKRFCWNCGRPVGRSDSETKGASEGWCPYCGSPYSFLPQLNPGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQAMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKRSKGQKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTEEQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLAALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAEEMSAQLTGVLREVVAQDT 4y3i A 1.69 BS01 LBV A 1 C24 I29 M174 Y176 F198 F203 S206 D207 I208 P209 Y216 R254 T256 S257 M259 H260 Y263 M267 S272 L273 S274 L286 H290 C21 I26 M171 Y173 F195 F200 S203 D204 I205 P206 Y213 R251 T253 S254 M256 H257 Y260 M264 S269 L270 S271 L283 H287 2.7.13.3 Q9RZA4 25650486 DPLPFFPPLYLGGPEITTENCEREPIHIPGSIQPHGALLTADGHSGEVLQMSLNAATFLGQEPTVLRGQTLAALLPEQWPALQAALPPGCPDALQYRATLDWPAAGHLSLTVHRVGELLILEFEPTEAWDSTGPHALRNAMFALESAPNLRALAEVATQTVRELTGFDRVMLYKFAPDATGEVIAEARREGLHAFLGHRFPASDIPAQARALYTRHLLRLTADTRAAAVPLDPVLNPQTNAPTPLGGAVLRATSPMHMQYLRNMGVGSSLSVSVVVGGQLWGLIACHHQTPYVLPPDLRTTLESLGRLLSLQVQVKEAH 4y73 A 2.14 BS01 XPY A 1 M192 G193 E194 G195 V200 A211 Y262 V263 M265 G268 A315 N316 L318 D329 M30 G31 E32 G33 V38 A49 Y100 V101 M103 G106 A153 N154 L156 D167 2.7.11.1 Q9NWZ3 TRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 4y73 C 2.14 BS01 XPY C 1 M192 E194 G195 V200 A211 V246 Y262 V263 Y264 M265 G268 A315 N316 L318 D329 M29 E31 G32 V37 A48 V83 Y99 V100 Y101 M102 G105 A152 N153 L155 D166 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASETVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS 4y73 D 2.14 BS01 XPY D 1 M192 G193 E194 G195 V200 A211 K213 Y262 V263 M265 G268 D272 A315 N316 L318 D329 M29 G30 E31 G32 V37 A48 K50 Y99 V100 M102 G105 D109 A152 N153 L155 D166 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 4ydq A 2.30 BS01 ANP A 1 R390 E392 K394 F399 I400 R401 T402 F405 Q475 A476 A477 T478 T512 R514 R137 E139 K141 F146 I147 R148 T149 F152 Q222 A223 A224 T225 T259 R261 6.1.1.15 Q8I5R7 25817387 MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKNHGFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNQSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 4ydq A 2.30 BS02 HFG A 1 F335 E338 V339 P358 T359 E361 R390 W407 E409 H411 F454 T478 H480 W509 G510 F82 E85 V86 P105 T106 E108 R137 W154 E156 H158 F201 T225 H227 W256 G257 6.1.1.15 Q8I5R7 25817387 MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKNHGFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNQSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 4ydq B 2.30 BS01 ANP B 1 R390 F399 I400 R401 T402 F405 Q475 A476 A477 T478 T512 R514 R131 F140 I141 R142 T143 F146 Q216 A217 A218 T219 T253 R255 6.1.1.15 Q8I5R7 25817387 MAITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLTLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 4yiv A 1.93 BS01 CO A 1 D102 R111 H363 D34 R43 H275 S8GKS3 25955165 GNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPGQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTTALQCPDSFGACDVQACKRQKTSCVGGQIQSTSV 4yiv A 1.93 BS02 CO A 2 E83 H89 H90 K285 E15 H21 H22 K217 S8GKS3 25955165 GNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPGQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTTALQCPDSFGACDVQACKRQKTSCVGGQIQSTSV 4ynd A 2.79 BS04 4GQ A 1 T105 L141 K145 I149 V179 N180 N182 G183 F184 T185 A203 T238 S239 Y240 S257 Y258 T103 L139 K143 I147 V177 N178 N180 G181 F182 T183 A201 T236 S237 Y238 S255 Y256 2.1.1.-,2.1.1.43 Q9NRG4 AEGLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEI 4yo6 A 2.32 BS01 4GD A 1 M192 G193 V200 A211 Y262 V263 Y264 M265 P266 G268 S269 L318 M30 G31 V38 A49 Y95 V96 Y97 M98 P99 G101 S102 L151 2.7.11.1 Q9NWZ3 TRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLATTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 4yo6 C 2.32 BS01 4GD C 1 M192 V200 A211 K213 V246 Y262 V263 Y264 M265 G268 L318 M29 V37 A48 K50 V80 Y96 V97 Y98 M99 G102 L152 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS 4yo6 D 2.32 BS01 4GD D 1 M192 G193 V200 A211 V246 Y262 V263 Y264 M265 G268 L318 M29 G30 V37 A48 V79 Y95 V96 Y97 M98 G101 L151 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASETVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 4yo6 D 2.32 BS02 4GD D 2 H166 F168 V205 N206 T208 V210 H3 F5 V42 N43 T45 V47 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASETVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 4yp2 B 1.35 BS01 NCA B 1 Y70 I71 F83 G109 N110 Y111 I155 E160 R163 Y70 I71 F83 G109 N110 Y111 I155 E160 R163 3.2.2.22 P16094 DVSFRLSGADPRSYGMFIKDLRNALPFREKVYNIPLLLPSVSGAGRYLLMHLFNYDGKTITVAVDVTNVYIMGYLADTTSYFFNEPAAELASQYVFRDARRKITLPYSGNYERLQIAAGKPREKIPIGLPALDSAISTLLHYDSTAAAGALLVLIQTTAEAARFKYIEQQIQERAYRDEVPSLATISLENSWSGLSKQIQLAQGNNGIFRTPIVLVDNKGNRVQITNVTSKVVTSNIQLLLNTRNI 4yp8 A 2.64 BS01 4GF A 1 M192 G193 E194 V200 A211 V246 Y262 V263 Y264 M265 P266 G268 S269 T280 L318 M29 G30 E31 V37 A48 V78 Y94 V95 Y96 M97 P98 G100 S101 T112 L150 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLATTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASETVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 4yp8 B 2.64 BS01 4GF B 1 M192 G193 E194 V200 A211 K213 V246 Y262 V263 Y264 M265 P266 N267 G268 S269 L318 M32 G33 E34 V40 A51 K53 V74 Y90 V91 Y92 M93 P94 N95 G96 S97 L146 2.7.11.1 Q9NWZ3 SDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 4yp8 C 2.64 BS01 4GF C 1 I185 M192 G193 E194 V200 A211 K213 V246 Y262 V263 Y264 M265 P266 N267 G268 S269 R273 T280 L318 I22 M29 G30 E31 V37 A48 K50 V80 Y96 V97 Y98 M99 P100 N101 G102 S103 R107 T114 L152 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASETVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS 4yxs A 2.11 BS01 III I 1 Q84 E127 F129 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 L205 E230 Y235 P236 F239 A240 D241 P243 I246 D328 Y330 Q71 E114 F116 R120 K155 P156 E157 F174 L185 C186 G187 T188 P189 E190 L192 E217 Y222 P223 F226 A227 D228 P230 I233 D315 Y317 2.7.11.11 P00517 25877959 SVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKDGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4yxs A 2.11 BS02 EMU A 1 L49 G50 V57 A70 V104 M120 E121 Y122 V123 E127 E170 N171 L173 T183 F327 L36 G37 V44 A57 V91 M107 E108 Y109 V110 E114 E157 N158 L160 T170 F314 2.7.11.11 P00517 25877959 SVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKDGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4yzu A 1.41 BS01 4K6 A 1 Y99 F174 S190 C191 Q192 S195 I213 W215 G216 E217 C220 Y86 F162 S180 C181 Q182 S185 I203 W205 G206 E207 C209 3.4.21.22 P00740 25937013 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGASALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT 4z0k A 1.41 BS01 4LN A 1 Y99 F174 S190 C191 Q192 S195 I213 S214 W215 G216 E217 E219 C220 Y86 F162 S180 C181 Q182 S185 I203 S204 W205 G206 E207 E208 C209 3.4.21.22 P00740 25937013 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGASALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKL 4z6h A 1.80 BS01 4L2 A 1 G43 F44 F45 F47 V49 I53 N100 Y106 G22 F23 F24 F26 V28 I32 N79 Y85 Q9H8M2 25864491 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMS 4z6h B 1.80 BS01 4L2 B 1 G43 F44 F45 V49 I53 N100 Y106 G22 F23 F24 V28 I32 N79 Y85 Q9H8M2 25864491 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMS 4z6i A 1.95 BS01 4L3 A 1 H42 G43 F44 F45 A46 F47 P48 V49 A54 N100 Y106 H21 G22 F23 F24 A25 F26 P27 V28 A33 N79 Y85 Q9H8M2 25864491 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMS 4ziy A 1.85 BS01 ANP A 1 S123 G124 K125 T126 T127 E172 H292 N296 R327 Y343 N344 S349 S117 G118 K119 T120 T121 E166 H283 N287 R318 Y334 N335 S340 6.3.2.10 A0A0A2TK68 STVPLEPWTAQQLQQATQGYWHKDQIPQTEIKRILTDSRHAESGDAFLALKGERFDAHNFVAQVVANGCQVAIVERPIDAEIAQLVVADTRLALGQLGAYRREQNAQLKVIALTGSSGKTTTKEMLGSILSRLAPTLITRGNLNNDLGVPMMLLELRKEHQYAVMELGANHQGEIDYTSKIVQPHVAGILNIGTAHFGGRDGICRAKSEIYRHILPQGVAIVPQQDDFTAEIREAAKSHQIMSFGAGGDVFATEIELLPQSANFQLHTPQGSSFVRLPFAGEHNVQNATAAVAFALALGVSLEDIVKGLEQAQGAKGRLNFIQKTPHLFIDDTYNANPTSMRAAAQVLLQQNGIKVMVMGDIGELSWQEHHDLGRDLAELPLDHIVAVGQFASAALEGTKLKAFQTQAEALPFLINLIQTHQSMSFLFKGSRFTHMETLMADLMEK 4zjp A 1.63 BS01 RIP A 1 N36 F38 F39 D112 R113 A160 R164 F187 N213 D237 Q257 N14 F16 F17 D90 R91 A138 R142 F165 N191 D215 Q235 3.6.3.17 A6VKT0 MQETIALTVSTLDNPFFVSLKDGAQKKATELGYKLVVLDSQNDPSKELSNVEDLTVRGAKVLLINPTDSAAVSNAVAIANRNKIPVITLDRGAAKGEVVSHIASDNVAGGKMAGDFIAQKLGDGAKVIQLEGLAGTSAARERGEGFKQAIEAHKFDVLASQPADFDRTKGLNVTENLLASKGSVQAIFAQNDEMALGALRAISAAGKKVLVVGFDGTEDGVKAVKSGKLAATVAQQPELIGSLGVETADKILKGEKVDAKIPVALKVVTE 4zpj A 2.24 BS01 ZN A 1 D227 H232 D149 H154 D1C6A8 EPIRIGVLLTLSGPQGVNGEGNLRGLTLALDQAGMQFGGRPVELIIEDSAGQPEQAITKTRQLIERDRVHLIAGITLSNEAAAVRDILVQAEMPTIVTNAGLQALTRDPAMRSPYLFRVSFANGQYDAPAADYAYETLGYRRMVLHAADYAAGHEEMAAFRSRFEQAGGEIVDEVVAPIGTQDFGPYLQRIEQAAAEADAVFAFHGTSTDAIRFLVQYQEFGLKDSIPLIPSGADVDQSILPEIGDAALGLVSGTLYTAYNDTPESQEFVEAFTARHEGILPGLVDYAGYIGGRVIAEALTAIDGEVENKEALLEALKAVEFTGPAGNFRFHPESQGPVTTILLCRVEQLDDGTYANIVVDRIPDFDDLSF 4zpj A 2.24 BS02 ZN A 2 E343 E346 E265 E268 D1C6A8 EPIRIGVLLTLSGPQGVNGEGNLRGLTLALDQAGMQFGGRPVELIIEDSAGQPEQAITKTRQLIERDRVHLIAGITLSNEAAAVRDILVQAEMPTIVTNAGLQALTRDPAMRSPYLFRVSFANGQYDAPAADYAYETLGYRRMVLHAADYAAGHEEMAAFRSRFEQAGGEIVDEVVAPIGTQDFGPYLQRIEQAAAEADAVFAFHGTSTDAIRFLVQYQEFGLKDSIPLIPSGADVDQSILPEIGDAALGLVSGTLYTAYNDTPESQEFVEAFTARHEGILPGLVDYAGYIGGRVIAEALTAIDGEVENKEALLEALKAVEFTGPAGNFRFHPESQGPVTTILLCRVEQLDDGTYANIVVDRIPDFDDLSF 4zqb A 1.85 BS01 NAP A 1 R90 M100 G144 L145 G146 E147 L148 W166 S167 R168 S169 K171 L198 L199 P200 E204 T205 F226 R228 D252 V253 H276 S278 A279 Y313 R90 M100 G144 L145 G146 E147 L148 W166 S167 R168 S169 K171 L198 L199 P200 E204 T205 F226 R228 D252 V253 H276 S278 A279 Y313 1.1.1.79,1.1.1.81 Q3IWN8 MSRIALVTRLSPEAEAHWAGHLARALPGERIDGFRELSPAERAEVDIAIVANPDPADLAELPNLVWIHSLWAGVERLVAELGHLARPIVRLVDPELARTMAEAALAWTYYLFRDMPAYAAQQRARVWKGLPYKRPERTTVGVLGLGELGAAAALRLRDAGFDVHGWSRSPKEIAGVTCHAGEETLERMLGQVEILVCLLPLTGETRGLLDARRLACLPEGAQIVNFARGPILDSAALIEALDSGRIGHAVLDVFEVEPLPEASPFWGHPKVTVLPHISAATDPETASAIVGAHVADYRATGRIPPSVDLTRGY 4zqb A 1.85 BS02 SO4 A 1 W71 G73 R228 H276 W71 G73 R228 H276 1.1.1.79,1.1.1.81 Q3IWN8 MSRIALVTRLSPEAEAHWAGHLARALPGERIDGFRELSPAERAEVDIAIVANPDPADLAELPNLVWIHSLWAGVERLVAELGHLARPIVRLVDPELARTMAEAALAWTYYLFRDMPAYAAQQRARVWKGLPYKRPERTTVGVLGLGELGAAAALRLRDAGFDVHGWSRSPKEIAGVTCHAGEETLERMLGQVEILVCLLPLTGETRGLLDARRLACLPEGAQIVNFARGPILDSAALIEALDSGRIGHAVLDVFEVEPLPEASPFWGHPKVTVLPHISAATDPETASAIVGAHVADYRATGRIPPSVDLTRGY 4zqb B 1.85 BS01 NAP B 1 R90 M100 G144 L145 G146 E147 L148 W166 S167 R168 S169 K171 L198 L199 P200 E204 F226 A227 R228 D252 V253 H276 S278 A279 R311 Y313 R93 M103 G147 L148 G149 E150 L151 W169 S170 R171 S172 K174 L201 L202 P203 E207 F229 A230 R231 D255 V256 H279 S281 A282 R314 Y316 1.1.1.79,1.1.1.81 Q3IWN8 FQSMSRIALVTRLSPEAEAHWAGHLARALPGERIDGFRELSPAERAEVDIAIVANPDPADLAELPNLVWIHSLWAGVERLVAELGHLARPIVRLVDPELARTMAEAALAWTYYLFRDMPAYAAQQRARVWKGLPYKRPERTTVGVLGLGELGAAAALRLRDAGFDVHGWSRSPKEIAGVTCHAGEETLERMLGQVEILVCLLPLTGETRGLLDARRLACLPEGAQIVNFARGPILDSAALIEALDSGRIGHAVLDVFEVEPLPEASPFWGHPKVTVLPHISAATDPETASAIVGAHVADYRATGRIPPSVDLTRGY 4zqb B 1.85 BS02 SO4 B 1 G73 R228 H276 G76 R231 H279 1.1.1.79,1.1.1.81 Q3IWN8 FQSMSRIALVTRLSPEAEAHWAGHLARALPGERIDGFRELSPAERAEVDIAIVANPDPADLAELPNLVWIHSLWAGVERLVAELGHLARPIVRLVDPELARTMAEAALAWTYYLFRDMPAYAAQQRARVWKGLPYKRPERTTVGVLGLGELGAAAALRLRDAGFDVHGWSRSPKEIAGVTCHAGEETLERMLGQVEILVCLLPLTGETRGLLDARRLACLPEGAQIVNFARGPILDSAALIEALDSGRIGHAVLDVFEVEPLPEASPFWGHPKVTVLPHISAATDPETASAIVGAHVADYRATGRIPPSVDLTRGY 5ai1 A 2.10 BS01 EQU A 1 Y16 N40 F56 F86 M90 D103 Y15 N39 F55 F83 M87 D96 P07445 25947291 NLPTAQEVQGLMARYIELVDVGDIEAIVQMFADDATVENPFGQPPIHGREQIAAFFRQGLGGVRACLTGPVRASHNGCGAMPFRVEMVPCALDVIDVMRFDEHGRIQTMQAFWSEVNLSV 5al9 A 1.37 BS01 HEM A 1 P60 S61 W67 P162 D163 G164 V171 F175 L188 I189 A191 H192 G195 E196 C197 H198 F201 S202 Y204 W208 S252 F284 P27 S28 W34 P129 D130 G131 V138 F142 L155 I156 A158 H159 G162 E163 C164 H165 F168 S169 Y171 W175 S219 F251 1.11.1.5 Q4Q3K2 25941976 SEEPPFDIRALRADIEDMISEKLELGPSLIRLAWHEAASYDCFKKDGSPNSASMRFKPECLYAGNKGLDIPRKALETLKKKYPQISYADLWVLAAYVAIEYMGGPTIPFCWGRVDAKDGSVCGPDGRLPDGSKTQSHVREVFRRLGFNDQETVALIGAHTCGECHIEFSGYHGPWTHRKNGFDNSFFTQLLDEDWVLNPKVEQMQLMDRATTKLMMLPSDVCLLLDPSYRKYVELYAKDNDRFNKDFANAFKKLTELGTRNLHKAPA 5ala A 2.73 BS01 HEM A 1 P60 S61 I63 R64 W67 P162 G164 L188 A191 H192 C194 G195 E196 C197 H198 F201 S202 Y204 W208 L250 S252 F280 F284 P27 S28 I30 R31 W34 P129 G131 L155 A158 H159 C161 G162 E163 C164 H165 F168 S169 Y171 W175 L217 S219 F247 F251 1.11.1.11,1.11.1.5 Q4Q3K2 25941976 SEEPPFDIRALRADIEDMISEKLELGPSLIRLAWHEAASYDCFKKDGSPNSASMRFKPECLYAGNKGLDIPRKALETLKKKYPQISYADLWVLAAYVAIEYMGGPTIPFCWGRVDAKDGSVCGPDGRLPDGSKTQSHVREVFRRLGFNDQETVALIGAHTCGECHIEFSGYHGPWTHRKNGFDNSFFTQLLDEDWVLNPKVEQMQLMDRATTKLMMLPSDVCLLLDPSYRKYVELYAKDNDRFNKDFANAFKKLTELGTRNLHKAPA 5ala B 2.73 BS01 HEM B 1 P60 S61 W67 P162 D163 G164 V171 L188 A191 H192 C194 G195 E196 C197 H198 F201 S202 Y204 W208 L250 S252 F284 P27 S28 W34 P129 D130 G131 V138 L155 A158 H159 C161 G162 E163 C164 H165 F168 S169 Y171 W175 L217 S219 F251 1.11.1.11,1.11.1.5 Q4Q3K2 25941976 SEEPPFDIRALRADIEDMISEKLELGPSLIRLAWHEAASYDCFKKDGSPNSASMRFKPECLYAGNKGLDIPRKALETLKKKYPQISYADLWVLAAYVAIEYMGGPTIPFCWGRVDAKDGSVCGPDGRLPDGSKTQSHVREVFRRLGFNDQETVALIGAHTCGECHIEFSGYHGPWTHRKNGFDNSFFTQLLDEDWVLNPKVEQMQLMDRATTKLMMLPSDVCLLLDPSYRKYVELYAKDNDRFNKDFANAFKKLTELGTRNLHKAPA 5b8i A 1.85 BS01 ZN A 1 D136 N168 H217 H299 D107 N139 H188 H270 3.1.3.16 J3K9C5 LERVCKEVQAPAFHTPTNEQFWSPVDPSKPNLAFLKQHFYREGRLTEDQALWIIQAGTELLRAEPNLLEMDAPITVCGDVHGQYYDLMKLFEVGGDPAETRYLFLGDYVDRGYFSIECVLYLWALKIWYPNTLWLLRGNHECRHLTDYFTFKLECKHKYSEKVYDACMESFCALPLAAIMNKQFLCIHGGLSPELHTLEDIKSIDRFREPPTHGLMCDILWADPLEDFGTEKTGEYFVHNNVRGCSFFFSYPAACAFLEKNNLLSIIRAHEAQDAGYRMYQKTRTTGFPSVMTIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKITDMLIAILN 5b8i A 1.85 BS02 FE A 1 D108 H110 D136 D79 H81 D107 3.1.3.16 J3K9C5 LERVCKEVQAPAFHTPTNEQFWSPVDPSKPNLAFLKQHFYREGRLTEDQALWIIQAGTELLRAEPNLLEMDAPITVCGDVHGQYYDLMKLFEVGGDPAETRYLFLGDYVDRGYFSIECVLYLWALKIWYPNTLWLLRGNHECRHLTDYFTFKLECKHKYSEKVYDACMESFCALPLAAIMNKQFLCIHGGLSPELHTLEDIKSIDRFREPPTHGLMCDILWADPLEDFGTEKTGEYFVHNNVRGCSFFFSYPAACAFLEKNNLLSIIRAHEAQDAGYRMYQKTRTTGFPSVMTIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKITDMLIAILN 5b8i A 1.85 BS03 FK5 C 1 W370 S371 P373 F374 W341 S342 P344 F345 3.1.3.16 J3K9C5 LERVCKEVQAPAFHTPTNEQFWSPVDPSKPNLAFLKQHFYREGRLTEDQALWIIQAGTELLRAEPNLLEMDAPITVCGDVHGQYYDLMKLFEVGGDPAETRYLFLGDYVDRGYFSIECVLYLWALKIWYPNTLWLLRGNHECRHLTDYFTFKLECKHKYSEKVYDACMESFCALPLAAIMNKQFLCIHGGLSPELHTLEDIKSIDRFREPPTHGLMCDILWADPLEDFGTEKTGEYFVHNNVRGCSFFFSYPAACAFLEKNNLLSIIRAHEAQDAGYRMYQKTRTTGFPSVMTIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKITDMLIAILN 5b8i B 1.85 BS01 CA B 1 D31 D33 S35 T37 E39 E42 D31 D33 S35 T37 E39 E42 I9NKL8 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLSTRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENTDVSMSMTLDQF 5b8i B 1.85 BS02 CA B 2 D63 D65 D69 E74 D63 D65 D69 E74 I9NKL8 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLSTRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENTDVSMSMTLDQF 5b8i B 1.85 BS03 CA B 3 D100 D102 D104 F106 E111 D100 D102 D104 F106 E111 I9NKL8 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLSTRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENTDVSMSMTLDQF 5b8i B 1.85 BS04 CA B 4 D141 D143 D145 R147 E152 D141 D143 D145 R147 E152 I9NKL8 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLSTRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENTDVSMSMTLDQF 5b8i B 1.85 BS05 FK5 C 1 L116 M119 V120 L116 M119 V120 I9NKL8 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLSTRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENTDVSMSMTLDQF 5b8i C 1.85 BS01 FK5 C 1 Y36 F55 D56 R61 F64 V72 V73 I74 W77 A99 Y100 F105 F117 Y26 F45 D46 R51 F54 V62 V63 I64 W67 A89 Y90 F95 F107 J3K1B6 GVTKKILKEGNGVDKPVKGDDIVMNYRGCLYDSSKPSEHFMGRKFDSTEERGEFKTKIGIGVVIRGWDEAVLQMSLGEKSILTITDDYAYGARGFPGLIPPHATLVFEVELKGINSKRA