2mes A BS01 III B 1 Q8 E11 F12 A15 L18 F19 I27 L32 M36 M51 E54 V55 I63 F68 M71 M72 R74 K75 M76 D78 E84 E87 A88 V91 F92 M109 L112 E114 L116 M124 E127 A128 V136 F141 M144 M145 Q5 E8 F9 A12 L15 F16 I24 L29 M33 M48 E51 V52 I60 F65 M68 M69 R71 K72 M73 D75 E81 E84 A85 V88 F89 M106 L109 E111 L113 M121 E124 A125 V133 F138 M141 M142 P62155 24705785 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 2mpi B BS01 III A 1 F22 V23 N24 Q25 H26 L27 C28 L32 L36 V39 C40 T48 F1 V2 N3 Q4 H5 L6 C7 L11 L15 V18 C19 T27 P01308 25092300 FVNQHLCGSDLVEALYLVCGERGGFYTKPT 2mum A BS01 ZN A 1 C225 C227 H249 C252 C4 C6 H28 C31 P38806 TLYCFCQRVSFGEMVACDGPNCKYEWFHYDCVNLKEPPKGTWYCPECKIE 2mum A BS02 ZN A 2 C238 C243 C265 C268 C17 C22 C44 C47 P38806 TLYCFCQRVSFGEMVACDGPNCKYEWFHYDCVNLKEPPKGTWYCPECKIE 2muv C BS01 3LW C 1 V27 A30 G34 V9 A12 G16 B0LX40 25470189 SNDSSDPLVVAANIIGILHLILWILDRLFFK 2muv D BS01 3LW C 1 V27 G34 V9 G16 B0LX40 25470189 SNDSSDPLVVAANIIGILHLILWILDRLFFK 2muw B BS01 3LW C 1 A30 I33 A12 I15 B0LX40 25470189 SNDSSDPLVVAASIIGILHLILWILDRLFFK 3wxk A 2.37 BS01 GOL A 1 R84 E85 W104 D254 R86 E87 W106 D256 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxk A 2.37 BS02 GOL A 2 G275 T276 G277 F279 G277 T278 G279 F281 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxk B 2.37 BS01 GOL B 1 R84 E85 W104 Y139 D254 Q255 F279 R86 E87 W106 Y141 D256 Q257 F281 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxk C 2.37 BS01 GOL C 1 R84 E85 W104 D254 Q255 R86 E87 W106 D256 Q257 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxk D 2.37 BS01 GOL D 1 R84 E85 W104 Y139 D254 Q255 R86 E87 W106 Y141 D256 Q257 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxk D 2.37 BS02 GOL D 2 W104 F279 A316 I317 A318 W106 F281 A318 I319 A320 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxl A 1.90 BS02 ADP A 1 G10 T11 T12 S13 Q255 T273 G275 T276 F279 G12 T13 T14 S15 Q257 T275 G277 T278 F281 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxl B 1.90 BS01 GOL B 1 R84 E85 W104 D254 Q255 F279 R86 E87 W106 D256 Q257 F281 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxl B 1.90 BS02 ADP B 1 R22 R24 R477 E478 R24 R26 R479 E480 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxl B 1.90 BS03 ADP B 2 M1 Y3 D20 R22 R24 V26 M3 Y5 D22 R24 R26 V28 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxl C 1.90 BS01 GOL C 1 R84 E85 W104 Y139 R192 F279 E314 R86 E87 W106 Y141 R194 F281 E316 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxl C 1.90 BS02 GOL C 2 P25 V26 S27 V28 K68 P27 V28 S29 V30 K70 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wxl D 1.90 BS02 ADP D 1 M1 Y3 D20 R22 R24 V26 D69 M3 Y5 D22 R24 R26 V28 D71 2.7.1.30 D3KVM3 25315291 FTMKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAK 3wy9 A 2.30 BS01 III C 1 K125 F129 R132 T133 L166 K324 L359 A360 I384 I422 S423 K114 F118 R121 T122 L155 K313 L348 A349 I373 I411 S412 O59153 25428348 KPHVNIVFIGHVDHGKSTTIGRLLYDTGNIPETIIKKFESFKFAWVMDRLKEERERGITIDVAHTKFETPHRYITIIDAPGHRDFVKNMITGASQADAAVLVVAATDGVMPQTKEHAFLARTLGIKHIIVTINKMDMVNYDQKVFEKVKAQVEKLLKTLGYKDFPVIPTSAWNGDNVVKKSDKMPWYNGPTLIEALDQIPEPEKPIDKPLRIPIQDVYSIKGVGTVPVGRVETGKLKVGDVVIFEPASTIFHKPIQGEVKSIEMHHEPLQEALPGDNIGFNVRGVSKNDIKRGDVAGHTDKPPTVVRTKDTFKAQIIVLNHPTAITVGYSPVLHAHTAQIPVRFEQILAKVDPRTGNIVEENPQFIKTGDSAIVVLRPMKPVVLEPVKEIPQLGRFAIRDMGMTIAAGMVISIQKG 3wy9 A 2.30 BS02 GDP A 1 D17 H18 G19 K20 S21 T22 N144 K145 D147 M148 S181 A182 W183 D13 H14 G15 K16 S17 T18 N133 K134 D136 M137 S170 A171 W172 O59153 25428348 KPHVNIVFIGHVDHGKSTTIGRLLYDTGNIPETIIKKFESFKFAWVMDRLKEERERGITIDVAHTKFETPHRYITIIDAPGHRDFVKNMITGASQADAAVLVVAATDGVMPQTKEHAFLARTLGIKHIIVTINKMDMVNYDQKVFEKVKAQVEKLLKTLGYKDFPVIPTSAWNGDNVVKKSDKMPWYNGPTLIEALDQIPEPEKPIDKPLRIPIQDVYSIKGVGTVPVGRVETGKLKVGDVVIFEPASTIFHKPIQGEVKSIEMHHEPLQEALPGDNIGFNVRGVSKNDIKRGDVAGHTDKPPTVVRTKDTFKAQIIVLNHPTAITVGYSPVLHAHTAQIPVRFEQILAKVDPRTGNIVEENPQFIKTGDSAIVVLRPMKPVVLEPVKEIPQLGRFAIRDMGMTIAAGMVISIQKG 3wy9 B 2.30 BS01 III D 1 F129 T133 K324 L359 A360 I384 I422 S423 F118 T122 K313 L348 A349 I373 I411 S412 O59153 25428348 KPHVNIVFIGHVDHGKSTTIGRLLYDTGNIPETIIKKFESFKFAWVMDRLKEERERGITIDVAHTKFETPHRYITIIDAPGHRDFVKNMITGASQADAAVLVVAATDGVMPQTKEHAFLARTLGIKHIIVTINKMDMVNYDQKVFEKVKAQVEKLLKTLGYKDFPVIPTSAWNGDNVVKKSDKMPWYNGPTLIEALDQIPEPEKPIDKPLRIPIQDVYSIKGVGTVPVGRVETGKLKVGDVVIFEPASTIFHKPIQGEVKSIEMHHEPLQEALPGDNIGFNVRGVSKNDIKRGDVAGHTDKPPTVVRTKDTFKAQIIVLNHPTAITVGYSPVLHAHTAQIPVRFEQILAKVDPRTGNIVEENPQFIKTGDSAIVVLRPMKPVVLEPVKEIPQLGRFAIRDMGMTIAAGMVISIQKG 3wyp B 1.30 BS01 BSO B 1 N23 L25 S27 Y43 S45 V47 N49 W79 S88 T90 W92 W108 L110 D128 N10 L12 S14 Y30 S32 V34 N36 W66 S75 T77 W79 W95 L97 D115 P22629 25434833 EAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKP 3x11 A 2.15 BS01 III C 1 M5 Y7 Y59 E63 N66 M67 T73 Y74 N77 N80 Y84 I95 Y99 D114 Y123 W133 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 M5 Y7 Y59 E63 N66 M67 T73 Y74 N77 N80 Y84 I95 Y99 D114 Y123 W133 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 P18465 25480565 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRNARGYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 3x13 A 1.80 BS01 III C 1 Y7 D9 F22 S24 F36 Y59 R62 N63 I66 F67 N70 T73 D74 S77 L81 Y84 L95 S97 Y99 N114 Y116 Y123 T143 K146 W147 A150 V152 D156 Y159 W167 Y171 Y7 D9 F22 S24 F36 Y59 R62 N63 I66 F67 N70 T73 D74 S77 L81 Y84 L95 S97 Y99 N114 Y116 Y123 T143 K146 W147 A150 V152 D156 Y159 W167 Y171 P30460 25480565 GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIFKTNTQTDRESLRILRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAARVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 3x14 A 2.00 BS01 III C 1 M5 Y7 D9 F22 S24 F36 Y59 R62 N63 I66 F67 N70 T73 D74 S77 I80 L81 Y84 L95 S97 Y99 N114 Y116 Y123 T143 K146 W147 Q155 D156 Y159 W167 Y171 M5 Y7 D9 F22 S24 F36 Y59 R62 N63 I66 F67 N70 T73 D74 S77 I80 L81 Y84 L95 S97 Y99 N114 Y116 Y123 T143 K146 W147 Q155 D156 Y159 W167 Y171 P30460 25480565 GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIFKTNTQTDRESLRILLRYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAARVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 3x16 A 2.65 BS01 HEB A 1 G87 L88 I90 R91 W94 V223 P225 F245 L258 T259 G262 H263 G266 K267 C268 H269 T307 S308 W314 A374 F402 W406 G77 L78 I80 R81 W84 V213 P215 F235 L248 T249 G252 H253 G256 K257 C258 H259 T297 S298 W304 A364 F392 W396 1.11.1.21 Q31MN3 25479089 MHGGATTVNISTAEWWPKALNLDILSQHDRKTNPMGPDFNYQEEVKKLDVAALKQDLQALMTDSQDWFPADWGHYGGLMIRLTWHAAGTYRIADGRGGAGTGNQRFAPLNSWPDNTNLDKARRLLWPIKQKYGNKLSWADLIAYAGTIAYESMGLKTFGFAFGREDIWHPEKDIYWGPEKEWVPPSTNPNSRYTGDRELENPLAAVTMGLIYVNPEGVDGNPDPLKTAHDVRVTFARMAMNDEETVALTAGGHTVGKCHGNGNAALLGPEPEGADVEDQGLGWINKTQSGIGRNAVTSGLEGAWTPHPTQWDNGYFRMLLNYDWELKKSPAGAWQWEPINPREEDLPVDVEDPSIRRNLVMTDADMAMKMDPEYRKISERFYQDPAYFADVFARAWFKLTHRDMGPKARYIGPDVPQEDLIWQDPIPAGNRNYDVQAVKDRIAASGLSISELVSTAWDSARTYRNSDKRGGANGARIRLAPQKDWEGNEPDRLAKVLAVLEGIAAATGASVADVIVLAGNVGVEQAARAAGVEIVLPFAPGRGDATAEQTDTESFAVLEPIHDGYRNWLKQDYAATPEELLLDRTQLLGLTAPEMTVLIGGLRVLGTNHGGTKHGVFTDREGVLTNDFFVNLTDMNYLWKPAGKNLYEICDRKTNQVKWTATRVDLVFGSNSILRAYSELYAQDDNKEKFVRDFVAAWTKVMNADRFDLD 4ci4 A 2.30 BS01 Y1N A 1 L247 F273 C275 C276 Q277 T279 S280 Y314 F318 L321 M330 V332 M355 H440 V444 L460 Y464 L38 F54 C56 C57 Q58 T60 S61 Y95 F99 L102 M111 V113 M136 H221 V225 L241 Y245 2.3.1.48 Q07869 KSLAKRIYEAYLKNFNMNKVKARVILSPPFVIHDMETLCMAEKTLVKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDM 4ci5 A 1.77 BS01 Y1N A 1 F226 F282 Q286 R288 S289 A292 E295 H323 M329 L330 M364 H449 L453 L465 L469 Y473 F21 F65 Q69 R71 S72 A75 E78 H106 M112 L113 M147 H232 L236 L248 L252 Y256 P37231 PESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 4ci5 B 1.77 BS01 Y1N B 1 L255 F264 H266 R280 I281 G284 C285 R288 A292 M329 L330 L333 I341 L44 F53 H55 R63 I64 G67 C68 R71 A75 M112 L113 L116 I124 P37231 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGSPFVIYDMNSLMMGEDKIKFKHITPEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 4cl9 A 1.40 BS01 IES A 1 W81 P82 F83 Q84 Q85 K91 L92 L94 Y139 N140 D145 I146 M149 W40 P41 F42 Q43 Q44 K50 L51 L53 Y98 N99 D104 I105 M108 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4d2y A 1.98 BS03 L5Z A 1 M336 L337 Q478 P565 V567 M38 L39 Q169 P256 V258 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4d2y B 1.98 BS05 L5Z B 1 M336 L337 Q478 P565 V567 W678 Y706 M38 L39 Q171 P258 V260 W371 Y399 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4d30 B 1.96 BS05 EG8 B 1 M336 Q478 P565 V567 M38 Q171 P258 V260 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4d31 A 1.95 BS03 OLW A 1 M336 Q478 P565 V567 W678 Y706 M38 Q169 P256 V258 W369 Y397 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4d32 A 2.10 BS03 7F5 A 1 M336 L337 Q478 P565 A566 V567 F584 E592 M38 L39 Q169 P256 A257 V258 F275 E283 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4d32 B 2.10 BS04 7F5 B 1 M336 L337 Q478 P565 A566 V567 F584 E592 Y706 M38 L39 Q171 P258 A259 V260 F277 E285 Y399 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4d33 A 2.09 BS01 HEM A 1 W180 A183 R185 C186 V187 G188 L195 S228 M341 F355 S356 G357 W358 M360 E363 W449 F475 Y477 W103 A106 R108 C109 V110 G111 L118 S151 M264 F278 S279 G280 W281 M283 E286 W372 F398 Y400 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d33 A 2.09 BS03 6J0 A 1 L107 Q249 P336 V338 F355 G357 Y477 L41 Q172 P259 V261 F278 G280 Y400 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d33 A 2.09 BS04 MTL A 1 S248 R252 A268 N269 E271 I272 N340 D480 S171 R175 A191 N192 E194 I195 N263 D403 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d33 B 2.09 BS04 6J0 B 1 L107 Q249 P336 V338 G357 Y477 L39 Q171 P258 V260 G279 Y399 1.14.13.39 P29473 25489882 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d34 A 2.25 BS01 HEM A 1 W180 A183 R185 C186 V187 G188 S228 M341 F355 S356 W358 E363 W449 F475 Y477 W103 A106 R108 C109 V110 G111 S151 M264 F278 S279 W281 E286 W372 F398 Y400 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d34 A 2.25 BS03 E2Z A 1 Q249 P336 V338 E363 Y477 Q172 P259 V261 E286 Y400 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d34 B 2.25 BS05 E2Z B 1 L107 Q249 P336 V338 E363 Y477 L39 Q172 P259 V261 E286 Y400 1.14.13.39 P29473 25489882 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKLPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d35 A 2.18 BS03 4E8 A 1 L107 Q249 P336 V338 F355 Y477 L41 Q172 P259 V261 F278 Y400 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d35 B 2.18 BS05 4E8 B 1 L107 Q249 P336 V338 F355 W449 Y477 L39 Q172 P259 V261 F278 W372 Y400 1.14.13.39 P29473 25489882 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKLPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d36 A 2.05 BS03 HLW A 1 V106 L107 Q249 P336 V338 G357 W449 Y477 V40 L41 Q172 P259 V261 G280 W372 Y400 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d36 B 2.05 BS05 HLW B 1 L107 Q249 P336 V338 Y477 L39 Q171 P258 V260 Y399 1.14.13.39 P29473 25489882 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d37 A 2.10 BS03 9HL A 1 V106 L107 Q249 P336 V338 W449 Y477 V40 L41 Q171 P258 V260 W371 Y399 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d37 B 2.10 BS05 9HL B 1 V106 L107 Q249 P336 V338 W449 V38 L39 Q170 P257 V259 W370 1.14.13.39 P29473 25489882 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d38 A 2.30 BS03 L5Z A 1 V106 L107 Q249 P336 V338 Y477 V40 L41 Q171 P258 V260 Y399 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d38 B 2.30 BS05 L5Z B 1 V106 L107 Q249 P336 V338 V38 L39 Q170 P257 V259 1.14.13.39 P29473 25489882 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d39 A 2.00 BS01 HEM A 1 W180 C186 V187 G188 L195 S228 M341 F355 S356 G357 W358 M360 E363 W449 F475 Y477 W103 C109 V110 G111 L118 S151 M264 F278 S279 G280 W281 M283 E286 W372 F398 Y400 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d39 A 2.00 BS03 OLW A 1 V106 L107 Q249 P336 V338 F355 W449 Y477 V40 L41 Q172 P259 V261 F278 W372 Y400 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d39 A 2.00 BS04 MTL A 1 S248 A268 N269 E271 I272 N340 D480 S171 A191 N192 E194 I195 N263 D403 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d3a A 2.25 BS03 7F5 A 1 V106 L107 Q249 P336 A337 V338 F355 S356 V40 L41 Q172 P259 A260 V261 F278 S279 1.14.13.39 P29473 25489882 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d3a B 2.25 BS03 HEM B 1 W180 A183 R185 C186 V187 G188 S228 M341 F355 S356 G357 W358 M360 W449 F475 Y477 W102 A105 R107 C108 V109 G110 S150 M263 F277 S278 G279 W280 M282 W371 F397 Y399 1.14.13.39 P29473 25489882 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d3a B 2.25 BS05 7F5 B 1 L107 Q249 P336 A337 V338 F355 Y477 L39 Q171 P258 A259 V260 F277 Y399 1.14.13.39 P29473 25489882 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4d3b A 1.80 BS03 6J0 A 1 M336 L337 Q478 P565 V567 Y706 M38 L39 Q169 P256 V258 Y397 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4d3h A 2.00 BS01 2BA A 1 N24 R26 A27 T28 L45 G47 Q108 N33 R35 A36 T37 L54 G56 Q102 Q99WC0 SGLVPRGSHMKMIIAIVQDQDSQELADQLVKNNFRATKLATTGGFLRAGNTTFLCGVNDDRVDEILSVINQTCGNREQLVSPVEVEVGGATVFVMPVDAFHQF 4d3h A 2.00 BS02 2BA C 1 I7 G34 G35 F36 L37 N41 T97 F99 I16 G43 G44 F45 L46 N50 T91 F93 Q99WC0 SGLVPRGSHMKMIIAIVQDQDSQELADQLVKNNFRATKLATTGGFLRAGNTTFLCGVNDDRVDEILSVINQTCGNREQLVSPVEVEVGGATVFVMPVDAFHQF 4d3h B 2.00 BS01 2BA A 1 I7 G34 G35 F36 L37 N41 E92 T97 F99 I15 G42 G43 F44 L45 N49 E87 T92 F94 Q99WC0 GLVPRGSHMKMIIAIVQDQDSQELADQLVKNNFRATKLATTGGFLRAGNTTFLCGVNDDRVDEILSVINQTCGNREQLVSPIPVEVEVGGATVFVMPVDAFHQF 4d3h C 2.00 BS01 2BA B 1 G34 G35 F36 L37 N41 V91 E92 G94 T97 F99 G43 G44 F45 L46 N50 V83 E84 G86 T89 F91 Q99WC0 SGLVPRGSHMKMIIAIVQDQDSQELADQLVKNNFRATKLATTGGFLRAGNTTFLCGVNDDRVDEILSVINQTCGNREQLVSPVEVGGATVFVMPVDAFHQF 4d6q A 1.29 BS02 PD2 A 1 Y136 F189 H192 E194 K210 W212 K245 H280 Y126 F179 H182 E184 K200 W202 K235 H270 Q6B0I6 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 4d6r A 1.40 BS04 IEJ A 2 K255 I259 P260 F261 K245 I249 P250 F251 Q6B0I6 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERY 4d6r A 1.40 BS05 IEJ A 3 K25 F28 N29 P54 E56 W57 Q151 K15 F18 N19 P44 E46 W47 Q141 Q6B0I6 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERY 4d6s A 1.40 BS02 DMD A 1 Q221 Y277 Y303 M306 Q211 Y267 Y293 M296 Q6B0I6 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWK 4itx A 1.61 BS02 CA A 1 N12 R15 N8 R11 4.4.1.8 P06721 KLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAYESSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFARIV 4jit B 2.80 BS01 3ZF B 1 R69 L90 D92 T93 G94 G95 T96 W134 I135 R67 L88 D90 T91 G92 G93 T94 W132 I133 2.4.2.22 H0Q6L9 23927482 EKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR 4jit C 2.80 BS01 3ZF C 1 R69 V91 D92 T93 G94 G95 T96 K115 W134 I135 R67 V89 D90 T91 G92 G93 T94 K113 W132 I133 2.4.2.22 H0Q6L9 23927482 EKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR 4jls A 2.20 BS01 3ZE A 1 L90 V91 D92 T93 G94 G95 T96 K115 T133 W134 I135 L71 V72 D73 T74 G75 G76 T77 K96 T114 W115 I116 2.4.2.22 H0Q6L9 23927482 EKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR 4kwo A 1.32 BS01 1UD A 1 L68 L100 D102 Y106 Q107 D156 C158 I201 Q203 G229 G230 L231 A232 Y258 M260 G261 D280 L46 L78 D80 Y84 Q85 D125 C127 I170 Q172 G198 G199 L200 A201 Y227 M229 G230 D249 2.4.2.29 P28720 25483606 DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAAGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSTKQSEEGVTFKHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 4lap A 1.12 BS01 1VT A 1 I10 D15 D33 Y79 G80 D81 S83 F116 D119 L125 G221 T222 T223 Y226 I300 I304 I10 D15 D33 Y79 G80 D81 S83 F116 D119 L125 G221 T222 T223 Y226 I300 I304 3.4.23.22 P11838 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 4lbu A 1.17 BS01 1WJ A 1 T47 L68 G69 N70 D102 Y106 Q107 D156 C158 I201 Q203 G229 G230 L231 A232 M260 G261 D280 T38 L59 G60 N61 D93 Y97 Q98 D142 C144 I187 Q189 G215 G216 L217 A218 M246 G247 D266 2.4.2.29 P28720 25483606 DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 4lks A 1.50 BS01 CA A 1 N37 D40 D42 T45 A155 N32 D35 D37 T40 A150 Q0TRJ3 LYKKAGSEFALDSSKLEAIYATSEADRDYKENAVDGDENTIWHSAYQAADKLPVSITIKLDKAYDLNQIDYLPRQNSRNGHVTEYKIETSLDNENWTEVRTGNLEVNEAGNALANRGYNPIRFNTINAQYLRFTALKTLGDTNNKYASAAELVFYGK 4lks A 1.50 BS02 GAL A 1 H48 Y51 R79 N84 Y151 H43 Y46 R74 N79 Y146 Q0TRJ3 LYKKAGSEFALDSSKLEAIYATSEADRDYKENAVDGDENTIWHSAYQAADKLPVSITIKLDKAYDLNQIDYLPRQNSRNGHVTEYKIETSLDNENWTEVRTGNLEVNEAGNALANRGYNPIRFNTINAQYLRFTALKTLGDTNNKYASAAELVFYGK 4mtb A 1.22 BS02 BZY A 1 H57 N97 T98 Q175 D189 S190 C191 Q192 S195 V213 S214 W215 G216 G219 C220 G226 H40 N79 T80 Q155 D171 S172 C173 Q174 S177 V191 S192 W193 G194 G196 C197 G204 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 4nni A 2.64 BS01 VGL A 1 F307 R357 F30 R80 P9WH43 NLYFQHMRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGLVHISELAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAETNEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAA 4nni A 2.64 BS02 VGL A 2 F310 E318 R357 F33 E41 R80 P9WH43 NLYFQHMRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGLVHISELAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAETNEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAA 4nni B 2.64 BS02 VGL B 2 K303 F310 E318 R357 K26 F33 E41 R80 P9WH43 NLYFQHMRHFARTHAIGQIVPGKVTKLVPFGAFVRVEEGIEGLVHISELAERHVEVPDQVVAVGDDAMVKVIDIDLERRRISLSLKQANEDYTEEFDPAKYGMADSYDEQGNYIFPEGFDAETNEWLEGFEKQRAEWEARYAEAERRHKMHTAQMEKFAAA 4no3 A 1.70 BS01 III C 1 M5 Y7 M45 E63 R65 K66 V67 T73 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 Q155 L156 Y159 T163 W167 Y171 M5 Y7 M45 E63 R65 K66 V67 T73 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 Q155 L156 Y159 T163 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 4no5 A 2.10 BS01 III C 1 M5 Y7 M45 E63 K66 V67 A69 T73 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 M5 Y7 M45 E63 K66 V67 A69 T73 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE 4npi A 1.94 BS01 NAD A 1 I165 S166 P167 W168 K192 S194 E195 F224 G225 K226 G230 E231 F244 G246 E247 T250 E268 L269 G270 C302 K352 E404 F406 I148 S149 P150 W151 K175 S177 E178 F207 G208 K209 G213 E214 F227 G229 E230 T233 E251 L252 G253 C285 K335 E387 F389 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4npi A 1.94 BS02 2VS A 1 R120 N169 L170 L173 L174 W177 E268 C302 Y462 R464 F470 R103 N152 L153 L156 L157 W160 E251 C285 Y445 R447 F453 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4npi B 1.94 BS02 2VS B 1 R120 N169 L174 W177 E268 V301 C302 Y462 R464 F470 R103 N152 L157 W160 E251 V284 C285 Y445 R447 F453 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4ns2 A 1.18 BS01 HEM A 1 T39 K42 F43 K45 H64 V67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 I107 F138 T39 K42 F43 K45 H64 V67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 I107 F138 P68082 GLSDGEWQQVLNVWGKVEADIAGHGQEVLIRLFTGHPETLEKFKKFKHLKTEAEMKASEKLKKHGTVVLTALGGILKKKGHHEAKLKPLAQSHATKHKIPIKYLEFISDAIIHVLHSKHPGDFGADAQGAMTKALELFRNDIAAKYKELGFQG 4o56 A 1.80 BS01 III B 1 K413 W414 D416 Y485 S487 H489 L490 L491 R516 F535 H538 K540 K54 W55 D57 Y126 S128 H130 L131 L132 R157 F176 H179 K181 2.7.11.21 P53350 LGSPGIQGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS 4o6l A 2.38 BS01 2QK A 1 I531 G532 V539 A551 K553 I586 M602 E603 C604 G605 I607 D608 L654 I663 D664 Q670 M671 Q672 P673 T675 I17 G18 V25 A37 K39 I72 M88 E89 C90 G91 I93 D94 L140 I149 D150 Q156 M157 Q158 P159 T161 2.7.12.1 P33981 NECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSTVNYMPPEAIKDMSISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQI 4o6l B 2.38 BS01 2QK B 1 I531 G532 S533 G534 S537 V539 A551 K553 I586 M602 E603 C604 G605 N606 I607 D608 L654 I663 D664 I17 G18 S19 G20 S23 V25 A37 K39 I72 M88 E89 C90 G91 N92 I93 D94 L140 I149 D150 2.7.12.1 P33981 NECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPGTVNYMPPEAIKDMISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQI 4oci A 2.01 BS01 CA A 1 D16 D18 D20 Y22 D9 D11 D13 Y15 N9UIU7 25502654 LKESFLLFDGDGDGYLTLNEFESLVRVLGVVMETSAIASTYNSNSKVRGMSYELFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEITDLFTFMGIDEQGVVKVDDFINQDNHHHHHH 4odc A 1.54 BS01 HEM A 1 M33 T40 Y43 F44 H46 W47 H60 K63 I68 L85 Q88 H89 L93 V95 N99 F100 L103 N104 L138 M32 T39 Y42 F43 H45 W46 H59 K62 I67 L84 Q87 H88 L92 V94 N98 F99 L102 N103 L137 P80043 SLSDKDKAAVRALWSKIGKSADAIGNDALSRMIVVYPQTKTYFSHWPDVTPGSPHIKAHGKKVMGGIALAVSKIDDLKTGLMELSEQHAYKLRVDPANFKILNHCILVVISTMFPKEFTPEAHVSLDKFLSGVALALAERYR 4odc B 1.54 BS01 HEM B 1 H41 F42 H63 K66 L88 L91 H92 L96 V98 N102 F103 L106 L141 H41 F42 H63 K66 L88 L91 H92 L96 V98 N102 F103 L106 L141 P80044 VEWTDKERSIISDIFSHMDYDDIGPKALSRCLIVYPWTQRHFSGFGNLYNAEAIIGNANVAAHGIKVLHGLDRGVKNMDNIAATYADLSTLHSEKLHVDPDNFKLLSDCITIVLAAKMGHAFTAETQGAFQKFLAVVVSALGKQYH 4oe2 A 2.00 BS01 NAD A 1 I165 S166 P167 W168 N169 L174 K192 P193 S194 E195 F224 G225 K226 G230 E231 F244 T245 G246 E247 T250 T253 A268 L269 G270 C302 E404 F406 F470 I148 S149 P150 W151 N152 L157 K175 P176 S177 E178 F207 G208 K209 G213 E214 F227 T228 G229 E230 T233 T236 A251 L252 G253 C285 E387 F389 F453 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFALGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4oe7 A 1.99 BS02 GXT A 1 S56 F147 T176 Y203 S45 F136 T165 Y192 4.1.2.- P75682 ALFTGIIPPVSTIFTADGQLDKPGTAALIDDLIKAGVDGLFFLGSGGEFSQLGAEERKAIARFAIDHVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWKVSEANLIRYFEQVADSVTLPVMLYNFPALTGQDLTPALVKTLADSRSNIIGIKDTIDSVAHLRSMIHTVKGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGYHQTLLQIPQMYQLDTPFVNVIKEAIVLCGRPVSTHVLPPASPLDEPRKAQLKTLLQQLKLC 4oe7 A 1.99 BS03 PYR A 1 P20 F52 G55 S56 G57 Y145 K174 G202 I219 P9 F41 G44 S45 G46 Y134 K163 G191 I208 4.1.2.- P75682 ALFTGIIPPVSTIFTADGQLDKPGTAALIDDLIKAGVDGLFFLGSGGEFSQLGAEERKAIARFAIDHVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWKVSEANLIRYFEQVADSVTLPVMLYNFPALTGQDLTPALVKTLADSRSNIIGIKDTIDSVAHLRSMIHTVKGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGYHQTLLQIPQMYQLDTPFVNVIKEAIVLCGRPVSTHVLPPASPLDEPRKAQLKTLLQQLKLC 4oe7 B 1.99 BS01 MG B 1 P20 G57 A221 P9 G46 A210 4.1.2.- P75682 ALFTGIIPPVSTIFTADGQLDKPGTAALIDDLIKAGVDGLFFLGSGGEFSQLGAEERKAIARFAIDHVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWKVSEANLIRYFEQVADSVTLPVMLYNFPALTGQDLTPALVKTLADSRSNIIGIKDTIDSVAHLRSMIHTVKGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGYHQTLLQIPQMYQLDTPFVNVIKEAIVLCGRPVSTHVLPPASPLDEPRKAQLKTLLQQLKLC 4oe7 B 1.99 BS02 GXP B 1 P20 F52 G55 S56 G57 Y145 F147 K174 T176 G202 I219 P9 F41 G44 S45 G46 Y134 F136 K163 T165 G191 I208 4.1.2.- P75682 ALFTGIIPPVSTIFTADGQLDKPGTAALIDDLIKAGVDGLFFLGSGGEFSQLGAEERKAIARFAIDHVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWKVSEANLIRYFEQVADSVTLPVMLYNFPALTGQDLTPALVKTLADSRSNIIGIKDTIDSVAHLRSMIHTVKGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGYHQTLLQIPQMYQLDTPFVNVIKEAIVLCGRPVSTHVLPPASPLDEPRKAQLKTLLQQLKLC 4ou2 A 2.15 BS02 6OA A 1 R120 N169 L170 L173 L174 V301 C302 Y462 R464 F470 R103 N152 L153 L156 L157 V284 C285 Y445 R447 F453 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFALGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4ou2 B 2.15 BS02 6OA B 1 R120 N169 L174 W177 V301 C302 Y462 R464 F470 R103 N152 L157 W160 V284 C285 Y445 R447 F453 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFALGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4ou2 C 2.15 BS02 6OA C 1 R120 N169 L174 W177 V301 C302 L303 Y462 R464 F470 R103 N152 L157 W160 V284 C285 L286 Y445 R447 F453 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFALGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4ou2 D 2.15 BS02 6OA D 1 R120 N169 L174 W177 C302 L303 Y462 R464 F470 R103 N152 L157 W160 C285 L286 Y445 R447 F453 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFALGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4oub A 2.19 BS01 NAD A 1 I165 S166 P167 W168 N169 K192 S194 E195 F224 G225 G230 E231 F244 G246 E247 T250 L269 C302 K352 E404 F406 I148 S149 P150 W151 N152 K175 S177 E178 F207 G208 G213 E214 F227 G229 E230 T233 L252 C285 K335 E387 F389 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFALGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4oub A 2.19 BS02 2VS A 1 R120 N169 L170 L174 W177 V301 C302 Y462 R464 F470 R103 N152 L153 L157 W160 V284 C285 Y445 R447 F453 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFALGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4oub C 2.19 BS02 2VS C 1 R120 N169 L170 L174 W177 V301 C302 Y462 R464 R103 N152 L153 L157 W160 V284 C285 Y445 R447 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFALGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4oub D 2.19 BS01 NAD D 1 I165 S166 P167 W168 K192 S194 E195 F224 G225 G230 E231 F244 T245 G246 E247 T250 T253 L269 C302 H349 K352 E404 F406 I148 S149 P150 W151 K175 S177 E178 F207 G208 G213 E214 F227 T228 G229 E230 T233 T236 L252 C285 H332 K335 E387 F389 Q83V33 SQLLNYIDGNFVTSASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLFEMSTSDGSGALNYTVRKPLGVIGVISPWNLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSFALGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 4pgk A 2.17 BS03 Y69 A 1 I40 G44 E45 A48 E73 Q123 I127 E128 F130 A131 A134 Y135 I190 L194 V197 L211 F215 I20 G24 E25 A28 E53 Q103 I107 E108 F110 A111 A114 Y115 I170 L174 V177 L191 F195 4.1.99.5 Q7V6D4 25222710 ALPDFTSDRYKDAYSRINAIVIEGEQEAHDNYIAIGTLLPDHVEELKRLAKMEMRHKKGFTACGKNLGVKADMDFAREFFAPLRDNFQTALGQGKTPTCLLIQALLIEAFAISAYHTYIPVSDPFARKITEGVVKDEYTHLNYGEAWLKANLESCREELLEANRENLPLILRMLDQVAGDAAVLQMDKEDLIEDFLIAYQESLTEIGFNTREITRMAAAAL 4pmi B 3.20 BS01 NUC A 1 T34 R35 Q36 A37 R38 R39 N40 R41 R42 R43 R44 R48 R50 T24 R25 Q26 A27 R28 R29 N30 R31 R32 R33 R34 R38 R40 P69718 25486594 DSLKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRARQRQIHSISERIRSTY 4pmi C 3.20 BS01 NUC A 1 P27 Q36 R39 N40 R41 R42 R43 R44 R46 R48 R50 R58 P15 Q24 R27 N28 R29 R30 R31 R32 R34 R36 R38 R46 P69718 25486594 LKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRARQRQIHSISERIRSTYL 4puv A 1.30 BS02 AZI A 2 V227 N254 H256 G286 I288 V227 N254 H256 G286 I288 1.7.3.3 Q00511 25005084 SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRS 4qt7 A 1.55 BS01 III B 1 Y90 Y92 R95 T96 T98 D99 D117 W118 Y131 P133 N135 Y136 Y9 Y11 R14 T15 T17 D18 D36 W37 Y50 P52 N54 Y55 2.7.10.2 P00523 25447263 SHMTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLTTGQTGYIPSNYVAPSD 4qts C 3.10 BS01 ZN C 1 H81 C83 C86 C89 H55 C57 C60 C63 Q59063 25451598 LTLKGKVILEGIIELETGMHINPVIRDAFGRILIPGSSLKGKIRALLERKDGLPHDCGECEICKIFGPHDSKNIKEPVRVIVRDAYLQPEERVVAGSKFKFEVVFNIYKESDKELIKKFIEGMKLLEDDYLGGSGSRGYGKIKFRDIKLICKPKEYYEGNENSKKESDEVESLNELESELDKIWGG 4qtt C 2.00 BS01 ZN C 1 C11 V13 C16 C112 C115 C11 V13 C16 C112 C115 P53738 25489090 MKFLTTNFLKCSVKACDTSNDNFPLQYDGSKCQLVQDESIEFNPEFLLNIVDRVDWPAVLTVAAELGNNALPPTKPSFPSSIQELTDDDMAILNDLHTLLLQTSIAEGEMKCRNCGHIYYIKNGIPNLLLPPHLV 4qtu B 2.12 BS01 SAM B 1 Y14 Y22 Q32 G55 C56 G57 L60 S61 D77 I78 S79 M82 Q98 D99 M100 I117 S118 A119 W122 Y3 Y11 Q21 G44 C45 G46 L49 S50 D66 I67 S68 M71 Q87 D88 M89 I106 S107 A108 W111 2.1.1.- P25627 25489090 IFYNDSEAHKYTGSTRVQHIQAKMTLRALELLNLQPCSFILDIGCGSGLSGEILTQEGDHVWCGLDISPSMLATGLSRELEGDLMLQDMGTGIPFRAGSFDAAISISAIQWLCNADTSYNDPKQRLMRFFNTLYAALKKGGKFVAQFYPKNDDQVDDILQSAKVAGFSGGLVVDDPESKKNKKYYLVLSSG 4qtu D 2.12 BS01 SAM D 1 Y22 Q32 G55 C56 G57 L60 S61 D77 I78 S79 M82 Q98 D99 M100 I117 S118 W122 Y5 Q15 G38 C39 G40 L43 S44 D60 I61 S62 M65 Q81 D82 M83 I100 S101 W105 2.1.1.- P25627 25489090 EAHKYTGSTRVQHIQAKMTLRALELLNLQPCSFILDIGCGSGLSGEILTQEGDHVWCGLDISPSMLATGLSRELEGDLMLQDMGTGIPFRAGSFDAAISISAIQWLCNDPKQRLMRFFNTLYAALKKGGKFVAQFYPKNDDQVDDILQSAKVAGFSGGLVVDDPESKKNKKYYLVLSSG 4r68 A 2.11 BS01 NAI A 1 G28 A29 V30 D51 V52 I53 T94 A95 G96 R98 I115 I119 V135 N137 H192 T247 I251 G28 A29 V30 D51 V52 I53 T94 A95 G96 R98 I115 I119 V135 N137 H192 T247 I251 1.1.1.27 P00338 25466195 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 4r68 A 2.11 BS02 W31 A 1 R105 L108 N137 L164 D165 R168 H192 G193 D194 V234 A237 Y238 I241 T247 R105 L108 N137 L164 D165 R168 H192 G193 D194 V234 A237 Y238 I241 T247 1.1.1.27 P00338 25466195 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 4r68 C 2.11 BS01 NAI C 1 V25 G28 A29 V30 D51 V52 I53 T94 A95 G96 I115 I119 V135 N137 L164 H192 T247 I251 V25 G28 A29 V30 D51 V52 I53 T94 A95 G96 I107 I111 V127 N129 L156 H184 T239 I243 1.1.1.27 P00338 25466195 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGALNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 4r68 C 2.11 BS02 W31 C 1 N137 L164 D165 R168 H192 G193 D194 A237 Y238 I241 T247 N129 L156 D157 R160 H184 G185 D186 A229 Y230 I233 T239 1.1.1.27 P00338 25466195 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGALNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 4r68 D 2.11 BS01 NAI D 1 V25 G28 A29 V30 D51 V52 I53 T94 A95 G96 I115 F118 I119 V135 N137 H192 T247 I251 V25 G28 A29 V30 D51 V52 I53 T94 A95 G96 I115 F118 I119 V135 N137 H192 T247 I251 1.1.1.27 P00338 25466195 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 4r69 A 3.19 BS01 NAI A 1 V25 G26 G28 A29 V30 D51 V52 I53 T94 A95 G96 A97 R98 I115 V135 S136 N137 L164 H192 T247 I251 V25 G26 G28 A29 V30 D51 V52 I53 T94 A95 G96 A97 R98 I109 V129 S130 N131 L158 H186 T241 I245 1.1.1.27 P00338 25466195 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 4r69 B 3.19 BS02 W13 B 1 R98 N137 L164 D165 R168 H192 G193 D194 V234 A237 Y238 I241 T247 R98 N130 L157 D158 R161 H185 G186 D187 V227 A230 Y231 I234 T240 1.1.1.27 P00338 25466195 ATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 4r8t B 2.13 BS01 III A 1 T18 T19 T20 G21 V22 Y23 R24 I25 M26 A27 R28 G29 Y34 A36 V40 M41 Y42 F46 T52 A57 I58 M59 S60 L65 D94 Q96 I98 V100 A106 N108 Q110 L140 D141 S142 I146 T1 T2 T3 G4 V5 Y6 R7 I8 M9 A10 R11 G12 Y17 A19 V23 M24 Y25 F29 T35 A40 I41 M42 S43 L48 D77 Q79 I81 V83 A89 N91 Q93 L123 D124 S125 I129 O90417 TTTGVYRIMARGILGTYQAGVGVMYENVFHTLWHTTRGAAIMSGEGKLTPYWGSVKEDRIAYGGPWRFDRKWNGTDDVQVIVVEPGKAAVNIQTKPGVFKTPLGEVGAVSLDYPRGTSGSPILDSNGDIIGLYGNGVELGD 4rce A 2.40 BS01 3LN A 1 G11 Q12 G13 L30 D32 V69 Y71 F108 W115 I118 D228 G230 G13 Q14 G15 L32 D34 V71 Y73 F110 W117 I120 D220 G222 3.4.23.46 P56817 25389560 FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4rcf A 1.78 BS01 3LO A 1 G11 Q12 G13 L30 D32 G34 S35 Y71 W76 F108 I118 R128 Y198 D228 G230 G13 Q14 G15 L32 D34 G36 S37 Y73 W78 F110 I120 R130 Y190 D220 G222 3.4.23.46 P56817 25389560 FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI 4rd5 A 2.70 BS01 NUC C 1 R227 K235 S277 G278 D279 K282 N283 R285 E287 N288 D289 L290 R43 K51 S93 G94 D95 K98 N99 R101 E103 N104 D105 L106 3.1.21.4 Q5F9M9 25429979 LGVQKIAPEQIRQLFAQTSEYHFSIPAKTEEKSNLNVFFGEGRRDKRGFVKPRPWYEVELIVSKDITSQEGYPVLKSFTVITDDGWQFQCKTSGDYSKNFRSENDLKTLGKWIKGRLESHGCLQNNEKITHETLREYGNDHFELRSTDNPDVWLLSFKGK 4rd5 A 2.70 BS02 NUC D 1 K212 E214 E215 K216 S217 N218 G224 E225 R227 R237 E243 I245 S247 K248 Y280 K282 R285 K28 E30 E31 K32 S33 N34 G40 E41 R43 R53 E59 I61 S63 K64 Y96 K98 R101 3.1.21.4 Q5F9M9 25429979 LGVQKIAPEQIRQLFAQTSEYHFSIPAKTEEKSNLNVFFGEGRRDKRGFVKPRPWYEVELIVSKDITSQEGYPVLKSFTVITDDGWQFQCKTSGDYSKNFRSENDLKTLGKWIKGRLESHGCLQNNEKITHETLREYGNDHFELRSTDNPDVWLLSFKGK 4rd5 B 2.70 BS01 NUC E 1 R227 K235 K275 S277 G278 D279 K282 N283 R285 N288 L290 R43 K51 K91 S93 G94 D95 K98 N99 R101 N104 L106 3.1.21.4 Q5F9M9 25429979 LGVQKIAPEQIRQLFAQTSEYHFSIPAKTEEKSNLNVFFGEGRRDKRGFVKPRPWYEVELIVSKDITSQEGYPVLKSFTVITDDGWQFQCKTSGDYSKNFRSENDLKTLGKWIKGRLESHGCLQNNEKITHETLREYGNDHFELRSTDNPDVWLLSFKG 4rd5 B 2.70 BS02 NUC F 1 K212 E214 K216 S217 N218 G224 E225 R227 K230 R237 E243 I245 S247 K248 Y280 K282 K28 E30 K32 S33 N34 G40 E41 R43 K46 R53 E59 I61 S63 K64 Y96 K98 3.1.21.4 Q5F9M9 25429979 LGVQKIAPEQIRQLFAQTSEYHFSIPAKTEEKSNLNVFFGEGRRDKRGFVKPRPWYEVELIVSKDITSQEGYPVLKSFTVITDDGWQFQCKTSGDYSKNFRSENDLKTLGKWIKGRLESHGCLQNNEKITHETLREYGNDHFELRSTDNPDVWLLSFKG 4rdm B 2.70 BS01 NUC E 1 R227 S277 G278 D279 K282 N283 R285 E287 N288 L290 R47 S97 G98 D99 K102 N103 R105 E107 N108 L110 3.1.21.4 Q5F9M9 25429979 LENCLGVQKIAPEQIRQLFAQTSEYHFSIPAKTEEKSNLNVFFGEGRRDKRGFVKPRPWYEVELIVSKDITSQEGYPVLKSFTVITDDGWQFQCKTSGDYSKNFRSENDLKTLGKWIKGRLESHGCLQNNEKITHETLREYGNDHFELRSTDNPDVWLLSFKGK 4rdm B 2.70 BS02 NUC F 1 K212 E214 K216 S217 N218 G224 E225 R237 E243 I245 S247 K248 Y280 K282 K32 E34 K36 S37 N38 G44 E45 R57 E63 I65 S67 K68 Y100 K102 3.1.21.4 Q5F9M9 25429979 LENCLGVQKIAPEQIRQLFAQTSEYHFSIPAKTEEKSNLNVFFGEGRRDKRGFVKPRPWYEVELIVSKDITSQEGYPVLKSFTVITDDGWQFQCKTSGDYSKNFRSENDLKTLGKWIKGRLESHGCLQNNEKITHETLREYGNDHFELRSTDNPDVWLLSFKGK 4rdn A 2.10 BS01 6MD A 1 K416 S417 Y418 D422 W432 C433 T435 N462 W486 K490 W491 D528 K17 S18 Y19 D23 W33 C34 T36 N63 W87 K91 W92 D129 Q9Y5A9 25412658 ENLYFQHMKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYK 4rdn B 2.10 BS01 6MD B 1 K416 S417 Y418 D422 W432 C433 N462 W486 W491 D528 K16 S17 Y18 D22 W32 C33 N62 W86 W91 D128 Q9Y5A9 25412658 NLYFQHMKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYK 4rea A 3.81 BS01 NUC C 1 N452 S460 N82 S90 3.1.21.-,3.1.4.1 Q9Y2M0 EFPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMELLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPALVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAV 4rea A 3.81 BS02 NUC D 1 D397 E398 K401 T405 D27 E28 K31 T35 3.1.21.-,3.1.4.1 Q9Y2M0 EFPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMELLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPALVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAV 4rea A 3.81 BS03 NUC E 1 E390 K406 Q409 E20 K36 Q39 3.1.21.-,3.1.4.1 Q9Y2M0 EFPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMELLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPALVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAV 4rea B 3.81 BS01 NUC C 1 Y374 R420 R424 K425 Y436 N621 L811 G978 P979 N980 D981 Y4 R50 R54 K55 Y66 N227 L390 G557 P558 N559 D560 3.1.21.-,3.1.4.1 Q9Y2M0 EFPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMEDELLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPALVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAV 4rea B 3.81 BS02 NUC E 1 S473 A474 Q492 K493 S103 A104 Q122 K123 3.1.21.-,3.1.4.1 Q9Y2M0 EFPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMEDELLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPALVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAV 4reb A 4.20 BS01 NUC F 1 Y374 R420 R424 Y436 V577 Y4 R50 R54 Y66 V167 3.1.21.-,3.1.4.1 Q9Y2M0 EFPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLARAKALAGQSVRICKGPRAVFSRILLLFSLTLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMVKHVTITCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPALVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVA 4reb H 4.20 BS01 NUC D 1 E398 K401 E28 K31 3.1.21.-,3.1.4.1 Q9Y2M0 EFPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPALVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVA 4rec A 2.20 BS01 NUC B 1 Y374 R420 R424 K425 Y436 S473 A474 K478 Q492 K493 V577 Y4 R50 R54 K55 Y66 S103 A104 K108 Q122 K123 V186 3.1.21.-,3.1.4.1 Q9Y2M0 EFPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMEDEGLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPALVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAV 4rfy A 1.70 BS01 3OU A 1 L408 G409 T410 G411 Q412 F413 V416 A428 K430 T474 E475 Y476 M477 A478 N479 G480 D521 N526 L528 D539 L542 S543 V546 Y551 L13 G14 T15 G16 Q17 F18 V21 A33 K35 T79 E80 Y81 M82 A83 N84 G85 D126 N131 L133 D144 L147 S148 V151 Y156 2.7.10.2 Q06187 25466710 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREARHAFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 4rg0 A 2.50 BS01 3P0 A 1 L408 G409 T410 G411 Q412 F413 V416 A428 K430 T474 E475 Y476 M477 A478 G480 H519 D521 N526 L528 S538 D539 V546 L13 G14 T15 G16 Q17 F18 V21 A33 K35 T79 E80 Y81 M82 A83 G85 H124 D126 N131 L133 S143 D144 V151 2.7.10.2 Q06187 25466710 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREARHAFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 4rgp A 2.30 BS01 CA A 1 E42 E45 E43 E46 I6U2G5 NATEQETLTILLDVYAYYQAYQIVKASQFFSDDIIFLLELLKERRELNVDFLFQNQVHLQELELTYHISLLDNAYEEELLANYIMDLEAKLRNDHIIDFVRSVSPILYRLLMRLMQSQVADINDYIYDAKNDQYDTWKFDKMHDSANPFVQNFVAKGRDSKITSRSLADFIQLTDLPQAIKDNILLLRDFEKSVRNPLAHLIKPFDEEELHRTTGFSSQTFLEKIIQLAVFSGIHYDNDKFYFDKVNELIKRIYQ 4rgp A 2.30 BS02 CA A 2 D127 A128 D134 D128 A129 D135 I6U2G5 NATEQETLTILLDVYAYYQAYQIVKASQFFSDDIIFLLELLKERRELNVDFLFQNQVHLQELELTYHISLLDNAYEEELLANYIMDLEAKLRNDHIIDFVRSVSPILYRLLMRLMQSQVADINDYIYDAKNDQYDTWKFDKMHDSANPFVQNFVAKGRDSKITSRSLADFIQLTDLPQAIKDNILLLRDFEKSVRNPLAHLIKPFDEEELHRTTGFSSQTFLEKIIQLAVFSGIHYDNDKFYFDKVNELIKRIYQ 4rgp B 2.30 BS01 CA B 1 E42 E45 N47 E43 E46 N48 I6U2G5 NATEQETLTILLDVYAYYQAYQIVKASQFFSDDIIFLLELLKERRELNVDFLFQNQVHLQELELTYHISLLDNAYEEELLANYIMDLEAKLRNDHIIDFVRSVSPILYRLLMRLMQSQVADINDYIYDAKNDQYDTWKFDKMHDSANPFVQNFVAKGRDSKITSRSLADFIQLTDLPQAIKDNILLLRDFEKSVRNPLAHLIKPFDEEELHRTTGFSSQTFLEKIIQLAVFSGIHYDNDKFYFDKVNELIKRIYQ 4rio A 2.69 BS01 3QX A 1 L828 G829 A853 V884 M902 E903 Y904 L905 G908 N954 L956 L14 G15 A39 V70 M88 E89 Y90 L91 G94 N140 L142 2.7.10.2 P52333 25453808 TIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGSERDVPALSRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLW 4rnb A 2.50 BS01 SUV A 1 A110 T111 V114 W120 I130 P131 Q134 T135 V138 E212 H224 F227 Y317 I320 N324 H350 Y354 A61 T62 V65 W71 I81 P82 Q85 T86 V89 E154 H166 F169 Y416 I419 N423 H447 Y451 O43614 PKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQGIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAGDPGELANAILKALELSRSDLSKFRENCKKRAMSFSKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFAHDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSC 4rot A 1.80 BS01 ZN A 1 D226 H228 D233 H235 3.1.1.1,3.1.1.2 V6W522 NLYFQGAMASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYLLHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQVLAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETNLEGNLGELAYWQGVFGQFEDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADFQAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS 4rot A 1.80 BS02 OXL A 1 R259 S261 R266 S268 3.1.1.1,3.1.1.2 V6W522 NLYFQGAMASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYLLHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQVLAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETNLEGNLGELAYWQGVFGQFEDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADFQAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS 4rre G 1.65 BS01 III H 1 R447 D449 Y455 V457 H459 R462 T464 Q465 W466 R11 D13 Y19 V21 H23 R26 T28 Q29 W30 6.3.2.- Q96J02 LGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQG 4ruw A 1.28 BS01 ZN A 1 H95 D97 H104 H134 H46 D48 H55 H85 3.1.4.- C5C3L1 RRDLRVMTWNIHTAVAPDAPGVVDEPRIAAVIRAEAPDVVVLNEVHRDAPGPGSHGDQPARLAELLAADGYVHTWFGLTEVDLPHEGAVLPGSSNGNVVMSRHPFVGGGVVVPLPNENYEPGGKLRRSLLTVTVDVPGLGDVVVHATHLSTPGSAVLVEDQKEQLRIVLDHVDARVPSVLAGDLNIWTTDVPTQPYSQNNLMQSWIAEDHLADTWRQVNDPGAGPTMTASYGRPESPHPDRRIDYVFATPAFDVVAGHVSLVDRFASDHLGVVMDLRLGGAPVAARTVLAGEDGLDGWAQLTASRPGRLRLSVCKNRGQADDDGTAVRAVLRNRAGVALRTVTDSGTSRDRCTVETWRGALPPGARLEACLVGADGTILASRTETL 4rxl A 1.52 BS01 WO4 A 1 A31 S33 G59 S60 A79 V144 P145 A146 N172 V173 Y191 A7 S9 G35 S36 A55 V120 P121 A122 N148 V149 Y167 Q9KLL7 TLHIYAASSMTNAVNALVADYSQQHDVKLVTVYGGSSSLARQIEAGAPADLFISANEEWANYLVEKGLVKPNKVVTLAANSLVLIRPTAQPVASFELQDAAAWQTALADSRLAVAQVDAVPAGMYAKQALQHAGVWPELESRLAQTNNVRLALALVERGESPLGIVYKTDALLSDKVTIVTAFSAQSHQPIRYPLAQLNDKAASAEWVAYLRSDAAQQILQRFGFESVS 4rxm A 1.75 BS01 INS A 1 F38 E39 D112 R113 S160 R164 W189 N216 D243 Q263 F18 E19 D92 R93 S140 R144 W169 N196 D223 Q243 A7JW62 SMKDELVVFSLPNLSSPFEVQLQKVAVETSKKLEIKLQVLDGQSSSTKQASDLENAITRGAKGIIISPNDVNAISGAVEEIIKEKIPAATLDRKVESSKPVPHFGANNYTGGQEVAKAVKAKYPNGAKIILLTGQPGSTSNIERTKGIRDELAAGGDKYKIVVDQTGNWLRSEGLRIIESVLPTLKEKPEVIISANDDMALGAIEALRSQGLKAGDILVTGFDSTPEALARVKDGWLYLTADQRPSFAVSTALEQVVGNIRESKEVSGADYPPKIILKDNLQEAERFAEIS 4rxm A 1.75 BS02 BGC A 1 D24 S50 E54 I55 D4 S30 E34 I35 A7JW62 SMKDELVVFSLPNLSSPFEVQLQKVAVETSKKLEIKLQVLDGQSSSTKQASDLENAITRGAKGIIISPNDVNAISGAVEEIIKEKIPAATLDRKVESSKPVPHFGANNYTGGQEVAKAVKAKYPNGAKIILLTGQPGSTSNIERTKGIRDELAAGGDKYKIVVDQTGNWLRSEGLRIIESVLPTLKEKPEVIISANDDMALGAIEALRSQGLKAGDILVTGFDSTPEALARVKDGWLYLTADQRPSFAVSTALEQVVGNIRESKEVSGADYPPKIILKDNLQEAERFAEIS 4rxm B 1.75 BS02 ASP B 1 L205 K206 E207 L183 K184 E185 A7JW62 KDELVVFSLPNLSSPFEVQLQKVAVETSKKLEIKLQVLDGQSSSTKQASDLENAITRGAKGIIISPNDVNAISGAVEEIIKEKIPAATLDRKVESSKPVPHFGANNYTGGQEVAKAVKAKYPNGAKIILLTGQPGSTSNIERTKGIRDELAAGGDKYKIVVDQTGNWLRSEGLRIIESVLPTLKEKPEVIISANDDMALGAIEALRSQGLKAGDILVTGFDSTPEALARVKDGWLYLTADQRPSFAVSTALEQVVGNIRESKEVSGADYPPKIILKDNLQEAERFAEI 4rxt A 1.35 BS01 ARA A 1 K42 Y48 W49 E75 D123 S176 R180 N231 D257 Q277 K12 Y18 W19 E45 D93 S146 R150 N201 D227 Q247 B9JKX8 SMAEVTIPIIVKDTTSFYWQIVLAGARKAGKDLGVKVPELGAQAETDVNGQISILENAVAGKPAAIVISPTEFKALGKPVDEAAKSVPIIGIDSGADSKAFKSFLTTDNTQGGRIAADGLAAAIKAMTGKEEGDVVIITNTPGAGSLEQRRTGFLDQVKTKYPGLKVVADKYADGQATTGLNIMTDLITANPKIVGVFASNLIMAQGVGQAIAENKLSDKVKVIGFDSDDKTLGFLKSGAIAGLVVQDPYRMGYDGIKTALAVSKGEKVEANVDTGANLVTKANMSDPKIEALIN 4rxu A 1.40 BS01 BGC A 1 E62 R64 D138 R139 D186 N188 F192 W242 N272 D298 K318 E15 R17 D91 R92 D139 N141 F145 W195 N225 D251 K271 A9WDY0 TQQLAVGIVLPTKDEPRWIQDETRFREALQQAGYQVEILFSQGSSAKEKENVEALIAKGIKVLIICPHDGTAAAAAAEAARAAGVKVISYDRLIRETDAVDYYVTFDSIAVGAQQAQYLVDHASGTGNPLYLYAGAASDNNAFLFFEGAWKVLQPKIADGTFVIKNSSEAVALQNKLDLTRDEMAKIIGQVTTNWDFNTAKNLAEANLTAATAADKGKVYILAPNDGTARAIADAFAADKDVTEYFVTGQDAEKASVQYIIDGRQSMTVFKDVRTLVQDAIKAAVALLQDQQPEARGTYNNGKKDVPAIQSPVVTVTRDNVRAALIDSGYYSASDFTNLP 4ry0 A 1.40 BS01 RIP A 1 N39 F42 D115 R116 D162 N164 R168 W192 N218 D243 Q263 N14 F17 D90 R91 D137 N139 R143 W167 N193 D218 Q238 Q2JZQ5 MADLIAIITPAHDNPFFKAEAVGAEAKAKELGYETLVMTHDDDANKQSEMIDTAIGRGAKAIILDNAGADASVAAVKKAKDAGIPSFLIDREINATGVAVAQIVSNNYQGAQLGAQEFVKLMGEKGNYVELVGKESDTNAGIRSQGYHDVIDDYPEMKSVAKQSANWSQTEAYSKMETILQANPDIKGVISGNDTMAMGAIAALQAAGRKDVIVVGFDGSNDVRDSIKSGGIKATVLQPAYAQAQLAVEQADAYIKNKTTPKEEKQLMDCVLINADNAGKLETFALT 4ry0 A 1.40 BS02 CA A 1 D174 D177 D178 D149 D152 D153 Q2JZQ5 MADLIAIITPAHDNPFFKAEAVGAEAKAKELGYETLVMTHDDDANKQSEMIDTAIGRGAKAIILDNAGADASVAAVKKAKDAGIPSFLIDREINATGVAVAQIVSNNYQGAQLGAQEFVKLMGEKGNYVELVGKESDTNAGIRSQGYHDVIDDYPEMKSVAKQSANWSQTEAYSKMETILQANPDIKGVISGNDTMAMGAIAALQAAGRKDVIVVGFDGSNDVRDSIKSGGIKATVLQPAYAQAQLAVEQADAYIKNKTTPKEEKQLMDCVLINADNAGKLETFALT 4ry8 A 1.75 BS01 SR1 A 1 F48 F49 H98 D122 Q135 F166 P168 R172 W224 D250 F17 F18 H67 D91 Q104 F135 P137 R141 W193 D219 A8F7U7 PKNVRIALVREVGEGSFFERYLAGAQSMARELGVTLLEATAHGDMARMVTMIENFITQRVDAIIIDHGRPDPLMPKIKEALDRGIRVVTFDLVVDDNRVPEIEQDDLLIGYLISKQLAVDFAGNANVIYVNVGGFAPLDKRDKMWQIIKWRFPGIKEVAKIGAVTGSTAADTQTRMEAAMKEKPEANAVLAMWDEFAKGAVRAIMQAGKSDQFKVYSVDVTTEDIQMMIQQNSPWVATVGTDSYAVGRLAVRAAAALVGGEKLPKYLLVEPQLITRQFLVDNNITNMDELVKALPALGESNLVWPEWLKALTEKN 4ry9 A 1.40 BS01 TLZ A 1 K43 Y49 F50 D123 S124 N171 R177 W208 N234 D260 N280 K10 Y16 F17 D90 S91 N138 R144 W175 N201 D227 N247 A1WJM2 GAFKIGVSMKTLSAPYFAAQMEAAKARGKELGYEVLATDAQGKLQKQISDVEDLVTRGVKLLIINPADSEGLVNAVNNASANGVKVVVIDSTLNPRANFVTQVQSSNSINGALVGHWVIEEVGNKSLKIALLSGEKGNPVGQERRLGVLSGIIEAQLRKFGKADLTVVGQGWGHWNDEGGLKAMEDLLVANKDINMVLGENDSMVLGARRAIESAGRTGILLVAAADAQKEALALIKQGKYGVTGLNDPALVARTAIDLGVKVVKGEVKDVPKQTLTTPAAITKGNVDKFYNPKAVF 4ry9 B 1.40 BS02 BCT B 1 P99 D101 S102 S124 T125 N171 P172 P66 D68 S69 S91 T92 N138 P139 A1WJM2 GAFKIGVSMKTLSAPYFAAQMEAAKARGKELGYEVLATDAQGKLQKQISDVEDLVTRGVKLLIINPADSEGLVNAVNNASANGVKVVVIDSTLNPRANFVTQVQSSNSINGALVGHWVIEEVGNKSLKIALLSGEKGNPVGQERRLGVLSGIIEAQLRKFGKADLTVVGQGWGHWNDEGGLKAMEDLLVANKDINMVLGENDSMVLGARRAIESAGRTGILLVAAADAQKEALALIKQGKYGVTGLNDPALVARTAIDLGVKVVKGEVKDVPKQTLTTPAAITKGNVDKFYNPKAVF 4rya A 1.50 BS01 MTL A 1 N32 E61 R65 Y135 E137 R184 G190 F245 V265 W300 W302 Q388 N11 E40 R44 Y114 E116 R163 G169 F224 V244 W279 W281 Q367 B9JRF8 AETLTIATVNNGDMIRMQKLTDDFTKKNPGIDVKWVTLEENVLRQKVTTDVATKGGQYDVMTIGIYEAPIWGKQGWLAPLDKLSADKDYDAADLLPPVRSGLTVDGKLYAAPFYAESSMVMYRKDLFEKAGLKMPEAPTWDFIKEAADKITDKSKEVYGICLRGKAGWGENIAFLSAMSNSFGARWFDEQWKPQFDQPEWKKTLQFYVDLMKKNGPPGASSNGFNENLALFQTGKCGMWIDATVAASFVTNPKESKVADQVGFALAPDNGLGKRGNWLWSWNLAIPAGSKKVEAAEKFIAWATSKDYLKLVAEKDGWANVPPGTRTSLYANADYQKAAPFAKMTLDSINSADPKHPTVKPVPYEGVQYVAIPEFQGIGTAVGQQFSAALAGQTTVDQALKTAQTLTEREMKKAGYPK 4tk1 A 2.70 BS01 III C 1 M326 F330 R653 Y673 M711 P713 Y719 D729 M731 M7 F11 R333 Y353 M389 P391 Y397 D407 M409 2.7.7.75,2.10.1.1 Q03555 PFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tk1 A 2.70 BS02 III D 1 H682 Q683 P685 H362 Q363 P365 2.7.7.75,2.10.1.1 Q03555 PFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tk1 B 2.70 BS01 III D 1 M326 D327 F330 R653 P654 I656 K658 P671 Y673 M711 L712 P713 Y719 V727 D729 M7 D8 F11 R324 P325 I327 K329 P342 Y344 M376 L377 P378 Y384 V392 D394 2.7.7.75,2.10.1.1 Q03555 PFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tk2 A 4.10 BS01 III D 1 M326 D327 F330 R653 I656 M711 P713 Y719 D729 M7 D8 F11 R330 I333 M386 P388 Y394 D404 2.7.7.75,2.10.1.1 Q03555 PFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tk2 B 4.10 BS01 III C 1 M326 D327 F330 R653 I656 Y673 M711 P713 Y719 V727 D729 M7 D8 F11 R330 I333 Y350 M386 P388 Y394 V402 D404 2.7.7.75,2.10.1.1 Q03555 PFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tk2 B 4.10 BS02 III D 1 H682 Q683 H359 Q360 2.7.7.75,2.10.1.1 Q03555 PFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tk3 A 2.70 BS02 III D 1 M326 D327 F330 R653 I656 K658 P671 Y673 M711 P713 P714 Y719 D729 M731 M8 D9 F12 R335 I338 K340 P353 Y355 M393 P395 P396 Y401 D411 M413 2.7.7.75,2.10.1.1 Q03555 SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tk3 B 2.70 BS02 III D 1 Q683 P685 Q361 P363 2.7.7.75,2.10.1.1 Q03555 SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRETEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tk4 A 3.60 BS01 III D 1 D327 F330 R653 I656 K658 Y673 M711 P713 P714 Y719 D729 D8 F11 R330 I333 K335 Y350 M388 P390 P391 Y396 D406 2.7.7.75,2.10.1.1 Q03555 PFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tk4 B 3.60 BS01 III C 1 M326 D327 F330 R653 P654 I656 K658 Y673 M711 P713 P714 V727 D729 M7 D8 F11 R323 P324 I326 K328 Y343 M381 P383 P384 V397 D399 2.7.7.75,2.10.1.1 Q03555 PFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL 4tt2 A 2.50 BS01 III P 1 V1013 V1018 P1019 D1020 E1062 Y1063 N1064 R1067 D1071 I1074 V35 V40 P41 D42 E84 Y85 N86 R89 D93 I96 3.6.1.3 Q6PL18 25486442 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 4tt4 A 2.70 BS01 ALY P 1 E1103 S1107 E125 S129 3.6.1.3 Q6PL18 25486442 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 4tt4 B 2.70 BS01 III P 1 T1084 A1087 I1088 E1091 T106 A109 I110 E113 3.6.1.3 Q6PL18 25486442 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 4tt4 B 2.70 BS02 ALY P 1 R1005 H1076 A1080 T1084 R27 H98 A102 T106 3.6.1.3 Q6PL18 25486442 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 4tte A 1.80 BS01 36Z A 1 R1007 V1008 K1011 P1012 V1013 Y1063 N1064 I1074 R29 V30 K33 P34 V35 Y85 N86 I96 3.6.1.3 Q6PL18 25486442 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 4tu4 A 1.73 BS01 37N A 1 R1007 V1008 V1013 D1014 E1017 Y1063 N1064 I1074 R29 V30 V35 D36 E39 Y85 N86 I96 3.6.1.3 Q6PL18 25486442 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 4u6x A 1.68 BS01 III P 1 M5 Y7 F9 M45 E63 R65 K66 V67 H70 Y99 Q155 L156 Y159 W167 Y171 M5 Y7 F9 M45 E63 R65 K66 V67 H70 Y99 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 4u6x A 1.68 BS02 III P 2 T73 D77 T80 L81 Y84 H114 Y116 Y123 T143 K146 W147 V152 Q155 L156 T73 D77 T80 L81 Y84 H114 Y116 Y123 T143 K146 W147 V152 Q155 L156 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 4u6x B 1.68 BS01 MG B 1 I35 E36 V37 Y66 I36 E37 V38 Y67 P61769 MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM 4u6y A 1.47 BS01 III P 1 M5 Y7 F9 M45 E63 R65 K66 V67 A69 H70 V76 D77 T80 L81 Y84 Y99 Y116 Y123 T143 K146 W147 A150 V152 Q155 L156 Y159 T163 W167 Y171 M5 Y7 F9 M45 E63 R65 K66 V67 A69 H70 V76 D77 T80 L81 Y84 Y99 Y116 Y123 T143 K146 W147 A150 V152 Q155 L156 Y159 T163 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 4ubq A 2.30 BS01 ZN A 1 H78 H80 H140 H74 H76 H136 3.5.2.6 Q9KVZ2 LPDLKIEKLEEGVYVHTSFEEVNGWGVVSKHGLVVLVNTDAYLIDTPFTATDTEKLVNWFVERGYKIKGTISSHFHSDSTGGIEWLNSQSIPTYASELTNELLKKDGKVQAKNSFSGVSYWLVKNKIEVFYPGPGHTQDNVVVWLPEKKILFGGCFVKPDGLGNLGDANLEAWPKSAKILMSKYVKAKLVVSSHSEIGDASLLKRTWEQAVKGLNESK 4ubq A 2.30 BS02 ZN A 2 D82 C159 H198 D78 C155 H194 3.5.2.6 Q9KVZ2 LPDLKIEKLEEGVYVHTSFEEVNGWGVVSKHGLVVLVNTDAYLIDTPFTATDTEKLVNWFVERGYKIKGTISSHFHSDSTGGIEWLNSQSIPTYASELTNELLKKDGKVQAKNSFSGVSYWLVKNKIEVFYPGPGHTQDNVVVWLPEKKILFGGCFVKPDGLGNLGDANLEAWPKSAKILMSKYVKAKLVVSSHSEIGDASLLKRTWEQAVKGLNESK 4uch A 2.20 BS03 OLW A 1 M341 H342 Q483 P570 V572 Y711 M40 H41 Q174 P261 V263 Y402 P29475 25489882 CPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPDVATKDQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWK 4uch B 2.20 BS03 HEM B 1 W414 C420 V421 G422 L429 S462 F589 S590 G591 W592 M594 E597 W683 F709 Y711 W101 C107 V108 G109 L116 S149 F276 S277 G278 W279 M281 E284 W370 F396 Y398 P29475 25489882 RFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPATKDQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4uch B 2.20 BS05 OLW B 1 M341 H342 Q483 P570 V572 W683 Y711 M38 H39 Q170 P257 V259 W370 Y398 P29475 25489882 RFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPATKDQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4ue3 L 1.40 BS01 NFV L 1 C76 C79 V82 H83 A507 P508 K509 L512 V530 P531 T532 C576 C579 C75 C78 V81 H82 A506 P507 K508 L511 V529 P530 T531 C575 C578 1.12.99.6 P0ACD8 STQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVITNAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDNANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSPGYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVKIHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMIPDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNVLPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLGRILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAPKGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEILRTLHSFDPCLACSTH 4ue3 S 1.40 BS03 SF3 S 1 E16 C17 T18 C19 C20 E76 T114 C115 C120 G148 C149 E13 C14 T15 C16 C17 E73 T111 C112 C117 G145 C146 1.12.99.6 P69739 KPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAEEVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTCASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVDRMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACSSTRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVV 4ueg A 1.93 BS01 MG A 1 D104 D106 H214 D101 D103 H205 2.4.1.186 O15488 TDQAFVTLATNDIYCQGALVLGQSLRRHRLTRKLVVLITPQVSDLLRRILSKVFDEVIEVNLIDSADYIHLAFLKRPELGLTLTKLHCWTLTHYSKCVFLDADTLVLSNVDELFDRGEFSAAPDPGWPDCFNSGVFVFQPSLHTHKLLLQHAMEHGSFDGADQGLLNSFFRNWSTTDIHKHLPFIYNLSSSPAFKQFGSSAKVVHFLGSMKPWNYKYQAAFLHLWWTVYQNNVLPLYKSVQA 4utf A 1.30 BS01 MAN A 1 H60 H63 I294 R295 E333 H335 E336 H30 H33 I264 R265 E303 H305 E306 3.2.1.130 D6D1V7 NNLGTELDYDTFCFYYDWYGSEAIDGQYRHWAHAIAPDPNGGSGQNPGTIPGTQESIASNFYPQLGRYSSSDPNILTKHMDMFVMARTGVLALTWWNEQDETEAKRIGLILDAADKKKIKVCFHLEPYPSRNVQNLRENIVKLITRYGNHPAFYRKDGKPLFFIYDSYLIEPSEWEKLLSPGGSITIRNTAYDALMIGLWTSSPTVQRPFILNAHFDGFYTYFAATGFTYGSTPTNWVSMQKWAKENGKIFIPSVGPGYIDTRIRPWNGSVIRTRTDGQYYDAMYRKAIEAGVSAISITSFNEWHEGSQIEPAVPYTSSEFTYLDYENREPDYYLTRTAYWVGKFRESK 4utf A 1.30 BS04 MAN A 3 F258 Y289 R295 N298 E336 F228 Y259 R265 N268 E306 3.2.1.130 D6D1V7 NNLGTELDYDTFCFYYDWYGSEAIDGQYRHWAHAIAPDPNGGSGQNPGTIPGTQESIASNFYPQLGRYSSSDPNILTKHMDMFVMARTGVLALTWWNEQDETEAKRIGLILDAADKKKIKVCFHLEPYPSRNVQNLRENIVKLITRYGNHPAFYRKDGKPLFFIYDSYLIEPSEWEKLLSPGGSITIRNTAYDALMIGLWTSSPTVQRPFILNAHFDGFYTYFAATGFTYGSTPTNWVSMQKWAKENGKIFIPSVGPGYIDTRIRPWNGSVIRTRTDGQYYDAMYRKAIEAGVSAISITSFNEWHEGSQIEPAVPYTSSEFTYLDYENREPDYYLTRTAYWVGKFRESK 4v28 A 1.20 BS01 4MU A 1 F253 A255 F258 Y289 N298 V301 E336 F223 A225 F228 Y259 N268 V271 E306 3.2.1.130 D6D1V7 25487964 NNLGTELDYDTFCFYYDWYGSEAIDGQYRHWAHAIAPDPNGGSGQNPGTIPGTQESIASNFYPQLGRYSSSDPNILTKHMDMFVMARTGVLALTWWNEQDETEAKRIGLILDAADKKKIKVCFHLEPYPSRNVQNLRENIVKLITRYGNHPAFYRKDGKPLFFIYDSYLIEPSEWEKLLSPGGSITIRNTAYDALMIGLWTSSPTVQRPFILNAHFDGFYTYFAATGFTYGSTPTNWVSMQKWAKENGKIFIPSVGPGYIDTRIRPWNGSVIRTRTDGQYYDAMYRKAIEAGVSAISITSFNQWHEGSQIEPAVPYTSSEFTYLDYENREPDYYLTRTAYWVGKFRESK 4v28 A 1.20 BS02 MAN A 1 Y46 W48 W126 H154 E156 Y195 Y252 Q333 E336 Y16 W18 W96 H124 E126 Y165 Y222 Q303 E306 3.2.1.130 D6D1V7 25487964 NNLGTELDYDTFCFYYDWYGSEAIDGQYRHWAHAIAPDPNGGSGQNPGTIPGTQESIASNFYPQLGRYSSSDPNILTKHMDMFVMARTGVLALTWWNEQDETEAKRIGLILDAADKKKIKVCFHLEPYPSRNVQNLRENIVKLITRYGNHPAFYRKDGKPLFFIYDSYLIEPSEWEKLLSPGGSITIRNTAYDALMIGLWTSSPTVQRPFILNAHFDGFYTYFAATGFTYGSTPTNWVSMQKWAKENGKIFIPSVGPGYIDTRIRPWNGSVIRTRTDGQYYDAMYRKAIEAGVSAISITSFNQWHEGSQIEPAVPYTSSEFTYLDYENREPDYYLTRTAYWVGKFRESK 4v3u A 2.30 BS01 HEM A 1 W414 C420 V421 G422 S462 M575 F589 S590 G591 W592 E597 W683 F709 Y711 W113 C119 V120 G121 S161 M274 F288 S289 G290 W291 E296 W382 F408 Y410 P29475 25489882 CPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVATKDQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4v3u A 2.30 BS03 EG8 A 1 M341 H342 Q483 P570 V572 M40 H41 Q182 P269 V271 P29475 25489882 CPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVATKDQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4v3u B 2.30 BS05 EG8 B 1 M341 H342 Q483 P570 V572 F589 M40 H41 Q173 P260 V262 F279 P29475 25489882 CPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPVATKDQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4v3v A 2.06 BS01 HEM A 1 W409 A412 R414 C415 V416 G417 F584 S585 W587 E592 W678 F704 Y706 W100 A103 R105 C106 V107 G108 F275 S276 W278 E283 W369 F395 Y397 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4v3v A 2.06 BS03 S8F A 1 L337 Q478 P565 V567 W678 Y706 L39 Q169 P256 V258 W369 Y397 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4v3v B 2.06 BS05 S8F B 1 Q478 P565 V567 W678 Y706 Q171 P258 V260 W371 Y399 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4v3w A 2.13 BS03 E2Z A 1 M336 Q478 P565 V567 E592 M38 Q169 P256 V258 E283 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4v3w A 2.13 BS05 H4B B 1 W306 W676 F691 H692 E694 W8 W367 F382 H383 E385 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4v3w B 2.13 BS05 E2Z B 1 Q478 P565 V567 W678 Q171 P258 V260 W371 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4v3x B 1.99 BS05 4E8 B 1 M336 L337 R414 Q478 P565 V567 Y706 M38 L39 R107 Q171 P258 V260 Y399 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4v3z A 2.05 BS03 9HL A 1 M336 L337 Q478 P565 V567 E592 W678 M38 L39 Q169 P256 V258 E283 W369 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4v3z B 2.05 BS05 9HL B 1 M336 L337 Q478 P565 V567 W678 M38 L39 Q171 P258 V260 W371 1.14.13.39 P29476 25489882 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4wck A 1.40 BS01 API A 1 N93 R94 H126 H128 W148 D155 M203 A206 L207 T208 A220 E222 N75 R76 H108 H110 W130 D137 M185 A188 L189 T190 A202 E204 B5ZAD9 SMEMIEKAPTDLEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKKDPEYPTIQEIKSLIAKPNIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFELNPSSVHALINDKSLWAKISSLPKIPLFNLRPRLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIRFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4wcm A 1.75 BS01 ZN A 1 H46 E49 H128 H27 E30 H109 B5ZAD9 MEMIEKAPTDLEDRDKAPHLLLLAGIHGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKKDPEYPTIQEIKSLIAKPNIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFELNPSSVHALINDKSLWAKISSLPKIPLFNLRPRLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVKPNEAGYTIRFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4wcn A 1.75 BS02 3KS A 1 R86 N93 R94 H126 H128 G130 G131 W148 M203 A206 L207 T208 A220 E222 K225 R68 N75 R76 H108 H110 G112 G113 W130 M185 A188 L189 T190 A202 E204 K207 B5ZAD9 SMEMIEKAPTDLEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKKDPEYPTIQEIKSLIAKPNIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFELNPSSVHALINDKSLWAKISSLPKIPLFNLRPRLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVNEAGYTIRFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4wf0 A 1.95 BS01 FMN A 1 V416 I417 T418 N425 N449 C450 R451 L453 Q454 V463 I466 R467 I470 L480 N482 N492 F494 L496 F509 I510 G511 Q513 V11 I12 T13 N20 N44 C45 R46 L48 Q49 V58 I61 R62 I65 L75 N77 N87 F89 L91 F104 I105 G106 Q108 O49003 TTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNCRFLQGPETDRATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNVFHLQPMRDYKGDVQYFIGVQLDGTERLHGAAEREAVCLIKKTAFQIAEAANDENYF 4wfj A 1.75 BS01 CA A 1 S76 F77 A78 F81 N133 S30 F31 A32 F35 N87 W0TJ64 25492421 NPYERGPDPTEDSIEAIRGPFSVATERVSSFASGFGGGTIYYPRETDEGTFGAVAVAPGFTASQGSMSWYGERVASQGFIVFTIDTNTRLDQPGQRGRQLLAALDYLVERSDRKVRERLDPNRLAVMGHSMGGGGSLEATVMRPSLKASIPLTPWNLDKTWGQVQVPTFIIGAELDTIAPVRTHAKPFYESLPSSLPKAYMELDGATHFAPNIPNTTIAKYVISWLKRFVDEDTRYSQFLCPNPTDRAIEEYRSTCPY 4wj7 A 2.75 BS01 III W 1 P82 S83 I136 H137 D138 I139 A140 A141 V142 S143 Y144 V145 R146 A158 C210 G214 F217 P28 S29 I82 H83 D84 I85 A86 A87 V88 S89 Y90 V91 R92 A104 C126 G130 F133 Q9BSQ5 PDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDEACCLVILAAESKVAAEELCCLLGQVFQVVY 4wj7 C 2.75 BS01 III Y 1 P82 S83 R85 I136 H137 D138 I139 A140 A141 V142 S143 Y144 V145 R146 A158 E207 C210 C211 G214 F217 V219 V220 P22 S23 R25 I76 H77 D78 I79 A80 A81 V82 S83 Y84 V85 R86 A98 E116 C119 C120 G123 F126 V128 V129 Q9BSQ5 DYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQEACCLVILAAESKVAAEELCCLLGQVFQVV 4wj7 D 2.75 BS01 III Z 1 P82 S83 S84 R85 I136 H137 D138 I139 A140 A141 V142 S143 Y144 V145 R146 K203 E207 C210 G214 F217 P20 S21 S22 R23 I74 H75 D76 I77 A78 A79 V80 S81 Y82 V83 R84 K109 E113 C116 G120 F123 Q9BSQ5 IEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQACCLVILAAESKVAAEELCCLLGQVF 4wnl C 2.80 BS01 III F 1 H150 K153 E190 T191 Q197 E198 I199 L200 L211 A214 W215 I218 H142 K145 E182 T183 Q189 E190 I191 L192 L203 A206 W207 I210 P36068 DIKVTPGTSELVEQILALLSRYLSSYIHVLNKFISHLRRVATLRFERTTLIKFVKKLRFYNDSVLSYNASEFINEGKNPGADSFDKVILPIASMFVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIESLRIGSNLLDLEVVQFAIKSADEDGTNIGETDNIFLQEILPVNSEEEFQTLSAAWHSILDGKLGALDEEFDVVATKWHD 4wnl D 2.80 BS01 III E 1 K153 T191 Q197 E198 I199 L200 A214 W215 I218 K140 T173 Q179 E180 I181 L182 A196 W197 I200 P36068 DIKVTPGTSELVEQILALLSRYLSSYIHVLNKFISHLRRVATLRFERTTLIKFVKKLRFYNDSVLSYNASEFINEADSFDKVILPIASMFVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIESLRIGSNLLDLEVVQFAIKSADEDGTDNIFLQEILPVNSEEEFQTLSAAWHSILDGKLGALDEEFDVVATKWH 4wpc A 3.34 BS01 I6P A 1 R141 K145 R109 K113 P38339 FSTPEIKKVLNSDVAINALLSRLKQSLLTCEEFMKFIRKKYAFEEEHVQELSKQYKHFFNIQNSSLKKMIHEVLGFDGKMAQVKQSYITALQKMYSEISSLLLTMTKLRKSVKENSKRLEKDVSDAIHSAEKAQSRYNSLCQDWDKLRKTKLTLRGSKTTKEQEEELLRKIDNADLEYKQKVDHSNSLRNTFITKERPRIVQELKDLILEIDTAMTIQLQKYTIWTENLVLNTGVTISPLDSTKSMKSFAGSVSNERDLYSFLNKYNQLINKNLIPVSYKKHP 4wwj A 1.90 BS01 FE A 1 E101 H104 H194 E100 H103 H193 1.-.-.- Q4K8M0 25489112 IDTFSRTGPLMEAASYPAWTQQLIQDCSESKRRVVEHELYQRMRDNKLSAKVMRQYLIGGWPVVEQFALYMAQNLTKTRFARHPGEDMARRWLMRNIRVELNHADYWVHWSRAHGVTLEDLQAQQVPPELHALSHWCWHTSSADSLIVAIAATNYAIEGATGEWSALVCSNGIYAAAFPEEDRKRAMKWLKMHAQYDDAHPWEALEIIVTLAGLNPTKALQAELRQAICKSYDYMYLFLERCMQQEKTAVTRERLA 4wwj B 1.90 BS01 FE B 1 E101 H104 E159 H194 E100 H103 E158 H193 1.-.-.- Q4K8M0 25489112 IDTFSRTGPLMEAASYPAWTQQLIQDCSESKRRVVEHELYQRMRDNKLSAKVMRQYLIGGWPVVEQFALYMAQNLTKTRFARHPGEDMARRWLMRNIRVELNHADYWVHWSRAHGVTLEDLQAQQVPPELHALSHWCWHTSSADSLIVAIAATNYAIEGATGEWSALVCSNGIYAAAFPEEDRKRAMKWLKMHAQYDDAHPWEALEIIVTLAGLNPTKALQAELRQAICKSYDYMYLFLERCMQQEKTAVTRERLA 4wwz A 1.80 BS02 3X1 A 1 Y41 Y57 G61 V64 F68 E101 H104 L134 E159 T162 W165 W190 H194 F239 Y40 Y56 G60 V63 F67 E100 H103 L133 E158 T161 W164 W189 H193 F238 Q4K8M0 25489112 IDTFSRTGPLMEAASYPAWTQQLIQDCSESKRRVVEHELYQRMRDNKLSAKVMRQYLIGGWPVVEQFALYMAQNLTKTRFARHPGEDMARRWLMRNIRVELNHADYWVHWSRAHGVTLEDLQAQQVPPELHALSHWCWHTSSADSLIVAIAATNYAIEGATGEWSALVCSNGIYAAAFPEEDRKRAMKWLKMHAQYDDAHPWEALEIIVTLAGLNPTKALQAELRQAICKSYDYMYLFLERCMQQEKTAVTRERLA 4wwz A 1.80 BS03 PSL A 1 R99 N103 H104 Y107 R98 N102 H103 Y106 Q4K8M0 25489112 IDTFSRTGPLMEAASYPAWTQQLIQDCSESKRRVVEHELYQRMRDNKLSAKVMRQYLIGGWPVVEQFALYMAQNLTKTRFARHPGEDMARRWLMRNIRVELNHADYWVHWSRAHGVTLEDLQAQQVPPELHALSHWCWHTSSADSLIVAIAATNYAIEGATGEWSALVCSNGIYAAAFPEEDRKRAMKWLKMHAQYDDAHPWEALEIIVTLAGLNPTKALQAELRQAICKSYDYMYLFLERCMQQEKTAVTRERLA 4wwz B 1.80 BS04 PSL B 1 R99 N103 H104 Y107 K189 R98 N102 H103 Y106 K188 Q4K8M0 25489112 IDTFSRTGPLMEAASYPAWTQQLIQDCSESKRRVVEHELYQRMRDNKLSAKVMRQYLIGGWPVVEQFALYMAQNLTKTRFARHPGEDMARRWLMRNIRVELNHADYWVHWSRAHGVTLEDLQAQQVPPELHALSHWCWHTSSADSLIVAIAATNYAIEGATGEWSALVCSNGIYAAAFPEEDRKRAMKWLKMHAQYDDAHPWEALEIIVTLAGLNPTKALQAELRQAICKSYDYMYLFLERCMQQEKTAVTRERLA 4wx0 A 1.70 BS02 HXD A 1 Y41 V64 V65 F68 E101 H104 E159 T162 W190 H194 M236 F239 Y40 V63 V64 F67 E100 H103 E158 T161 W189 H193 M235 F238 Q4K8M0 25489112 IDTFSRTGPLMEAASYPAWTQQLIQDCSESKRRVVEHELYQRMRDNKLSAKVMRQYLIGGWPVVEQFALYMAQNLTKTRFARHPGEDMARRWLMRNIRVELNHADYWVHWSRAHGVTLEDLQAQQVPPELHALSHWCWHTSSADSLIVAIAATNYAIEGATGEWSALVCSNGIYAAAFPEEDRKRAMKWLKMHAQYDDAHPWEALEIIVTLAGLNPTKALQAELRQAICKSYDYMYLFLERCMQQEKTAVTRERLA 4x0i A 3.09 BS01 HEM A 1 Y43 F44 H59 K62 V63 A66 L84 L87 H88 L92 V94 N98 F99 L102 V133 L137 Y42 F43 H58 K61 V62 A65 L83 L86 H87 L91 V93 N97 F98 L101 V132 L136 P69905 25497229 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 4x0i B 3.09 BS02 HEM D 1 T39 F42 F43 H64 K67 F72 L89 H93 L97 V99 N103 F104 L107 L142 T37 F40 F41 H62 K65 F70 L87 H91 L95 V97 N101 F102 L105 L140 P68871 25497229 HLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALA 4x0i D 3.09 BS01 HEM D 1 K56 S59 I60 K164 R199 Y200 K14 S17 I18 K122 R145 Y146 I7BA99 25497229 DEVEKACHLAQQLKEVSITLGVIYRTTERHSVQVEAHKTAIDKHADAVSRAVEALTRVDVALQRLKELGKANDTKAVKIIENITSARENLALFNNETQAVLTARDHVHKHRAAALQGWSDAKEKGDAAAEDVWVLLNAAKEKCSRYSSSSTSETELQKAIDAAANVGGLSAHKSKYGDVLNKFKLSNASVGAVRDTSGRGGKHMEKVNNVAKLLKDAEVSLAAAAAEIEEVKNAHETKV 4x0l B 2.05 BS01 HEM B 1 T39 F42 F43 H64 K67 V68 A71 F72 L89 L92 H93 L97 V99 N103 F104 L107 L142 T37 F40 F41 H62 K65 V66 A69 F70 L87 L90 H91 L95 V97 N101 F102 L105 L140 P68871 25497229 HLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKY 4x0m A 1.68 BS01 3WA A 1 I211 V219 A230 L260 S280 D281 Y282 H283 L340 I13 V21 A32 L62 S82 D83 Y84 H85 L142 2.7.11.30 P36897 25437144 GTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI 4x2j A 1.69 BS01 3WN A 1 I211 V219 A230 K232 E245 Y249 L260 S280 D281 Y282 H283 G286 L340 D351 I13 V21 A32 K34 E47 Y51 L62 S82 D83 Y84 H85 G88 L142 D153 2.7.11.30 P36897 25437144 GTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI 4x3j A 2.50 BS01 3WR A 1 A853 E872 V875 L876 I886 I902 E903 Y904 A905 F960 H962 L971 I980 A981 D982 F983 A9 E12 V15 L16 I26 I34 E35 Y36 A37 F92 H94 L103 I112 A113 D114 F115 2.7.10.1 Q02763 25437144 VLKARMDAAIKELEVLCKLGHHPNIINLLLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRNLAARNILVGENYVAKIADFGLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGID 4x7i A 1.77 BS01 3YS A 1 S10 G11 Q12 G13 L30 D32 G34 S35 Y71 F108 I110 I118 D228 S229 G230 T231 T232 A335 S15 G16 Q17 G18 L35 D37 G39 S40 Y76 F113 I115 I123 D233 S234 G235 T236 T237 A340 3.4.23.46 P56817 RGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMDCGYN 4x8r A 1.90 BS01 BDP A 1 T32 H33 E71 R87 S89 R147 R168 M170 Y191 N208 N209 S212 E235 T11 H12 E50 R66 S68 R126 R147 M149 Y170 N187 N188 S191 E214 A3PLM5 ECEVTLRSSDTHPDGYPTVEGVKFMAERAKELSNGRICIEVFPSSQLGEEKDTIEQTQFGVIDMVRASFGSFNDIVPEAQLLSLPYLFRSEEHLHNVMDGPIGDELAKAFEAKDLIAVAYYDGGSRSFYNSQKPITKVEDLKGMKFRVMQSDVFVDMMSALGANATPMPYGEVYSSIQTGVIDGAENNWPSYDSSGHFEVAKYYTLDQHLMVPELVAISKIKWDALSPEDQQVLRQAAEESEPVQRKLWAEQEKASEEKVVASGAEVVREIDKTPFIEAMAPVYEKYVTKSEYQDLVKRIQETQ 4xau C 3.00 BS01 PLP C 1 S53 G54 T55 F81 A83 T84 W128 D158 A160 H161 S182 Q184 K187 S58 G59 T60 F86 A88 T89 W133 D163 A165 H166 S187 Q189 K192 Q0H2X1 PRGSHMIPLFKVAVSPTALDRVAEVFASGYLGQGPRVAEFESALAARLGNPRVVSVHSGTSGLCLALRLLDAPEERDEVLSTPLTFEATNWAILADGRRITWVDVDPATLTMDLDDLERKISPATRAIIVVHWTGYPVDLDRLAGILDRAEREHGFRPAVIEDCAHAWGASYRGVPLGSHGNMCVFSFQALKHLTCGDGGLLTLPGDELHERAMLRRFYGIDRTADRLRGAYDVAEWGLKWHMTDLNAAIGLANLETVDEQLRLHRENAAFYDKELTGVPGLELLQRSPDREGSFYVYDVKVDDRPAFHRKMEAAGIMAGLVSRRNDEHSCVAHLRTSLPGLDSVYDRMVSLPVGWWLTEQDREHVVATIRSGW 4xau E 3.00 BS01 PLP C 1 Y214 K235 Y218 K239 Q0H2X1 RGSHMIPLFKVAVSPTALDRVAEVFASGYLGQGPRVAEFESALAARLGNPRVVSVHSGTSGLCLALRLLDAPEERDEVLSTPLTFEATNWAILADGRRITWVDVDPATLTMDLDDLERKISPATRAIIVVHWTGYPVDLDRLAGILDRAEREHGFRPAVIEDCAHAWGASYRGVPLGSHGNMCVFSFQALKHLTCGDGGLLTLPGDELHERAMLRRFYGIDRTADRLRGAYDVAEWGLKWHMTDLNAAIGLANLETVDEQLRLHRENAAFYDKELTGVPGLELLQRSPDREGSFYVYDVKVDDRPAFHRKMEAAGIMAGLVSRRNDEHSCVAHLRTSLPGLDSVYDRMVSLPVGWWLTEQDREHVVATIRSGW