3j80 b 3.75 BS01 ZN b 1 V35 K36 C37 N42 V34 K35 C36 N41 Q6CNL2 VLVQDLLHPTAASEARKHKLKTLVQSPRSHFLDVKCPGCLNITTVFSHAQTAVTCESCSTVLCTPTGGKAKLSEGTSFRRK 3j80 f 3.75 BS01 ZN f 1 C121 C142 C40 C61 P69061 KKVYTTPKKIRHKHKKVKLAVLNYYKVDDEGKVAKLRKECPNCGPGIFLANHGDRFYCGKCHSTFATQK 3j81 C 4.00 BS01 NUC 3 1 V85 P90 V126 A127 I130 V47 P52 V88 A89 I92 Q6CKL3 GWVPVTKLGRLVKAGKISSIEEIFLHSLPVKEFQIIDQLLPNLKDEVMNIKPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGIIIAKLSVIPIRRGYWGTNLGQPHSLATKTSGKCGSVSVRLIPAPRGSGIVASPAVKKLMQLAGVEDVYTSSTGSTRTLENTLKAAFVAIGNTYGFLTPNLWEVQALTPSPMDVYADYATAS 3j81 D 4.00 BS01 NUC 3 1 L142 R146 K148 L140 R144 K146 Q6CRK7 AIISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEIIIRATKVQDVVGENGRRINELTLLIEKRFKYKRGTIALYAERVHDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVISGKLRAARAKSMKFADGFLIHSGQPVNDFIETATRHVLLRQGVLGIKVKIMKDPSRNTSGPKALPDAVTIIEPKEEEPVLEPSVKDY 3j81 a 4.00 BS01 NUC 3 1 R42 K66 H80 A81 R82 R41 K65 H79 A80 R81 Q6CS01 PKKRASNGRNKKGRGHVKPVRCVNCSRSVPKDKAIKRMAIRNIVEAAAIRDLSEASVYAEYALPKTYNKLHYCISCAIHARIVRVRSRTDRRIRAPP 3j81 c 4.00 BS01 NUC 3 1 R64 R67 R59 R62 P33285 PVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTTRTIVRNVKGPVREGDILVLMESEREARRLR 3j81 f 4.00 BS01 ZN f 1 C121 C124 C139 C142 C40 C43 C58 C61 P69061 KKVYTTPKKIRHKHKKVKLAVLNYYKVDDEGKVAKLRKECPNCGPGIFLANHGDRFYCGKCHSTFATQK 3j81 i 4.00 BS01 NUC 1 1 G8 G9 K10 G4 G5 K6 P38912 NTKGGKKGRRGKNDSDGPKRELIYKEEGQEYAQITKMLGNGRVEASCFDGNKRMAHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNLDEARTLKNQGELPENAKI 3j81 i 4.00 BS02 NUC 3 1 K7 K10 G12 R13 K16 K67 W70 K3 K6 G8 R9 K12 K63 W66 P38912 NTKGGKKGRRGKNDSDGPKRELIYKEEGQEYAQITKMLGNGRVEASCFDGNKRMAHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNLDEARTLKNQGELPENAKI 3j81 j 4.00 BS01 NUC 1 1 S58 Q60 K61 R64 G66 K67 N68 Y102 Q103 K106 T107 S110 I111 R113 Y114 E117 K118 Y172 V223 A224 L227 S56 Q58 K59 R62 G64 K65 N66 Y100 Q101 K104 T105 S108 I109 R111 Y112 E115 K116 Y170 V210 A211 L214 P20459 TSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDETVWEGIEPPSKDVLDELKNYISAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITEVITKYGGVCNIT 3j81 j 4.00 BS02 NUC 3 1 R55 R57 R53 R55 P20459 TSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDETVWEGIEPPSKDVLDELKNYISAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITEVITKYGGVCNIT 3j81 m 4.00 BS01 NUC 1 1 R29 I30 Q31 Q32 R33 N34 G35 R36 P72 E73 F108 R11 I12 Q13 Q14 R15 N16 G17 R18 P54 E55 F90 P32911 ETATSNYIHIRIQQRNGRKTLTTVQGVPEEYDLKRILKVLKKDFACNGNIVKDPEMGEIIQLQGDQRAKVCEFMISQLGLQKKNIKIHGF 3j81 k 4.00 BS01 NUC 1 1 F321 F381 A382 E383 Q384 N385 R408 A409 F204 F241 A242 E243 Q244 N245 R258 A259 QATINIGTIGHVAHGKSTVVRAISGVQTVRLERNITIKLGYANAKIYKCQEEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFGGSILNGVFKLGDEIEIRPGIVTIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKK 3j81 k 4.00 BS02 MET k 1 G141 Y142 A143 E383 G40 Y41 A42 E243 QATINIGTIGHVAHGKSTVVRAISGVQTVRLERNITIKLGYANAKIYKCQEEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFGGSILNGVFKLGDEIEIRPGIVTIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKK 3wik A 2.00 BS01 LCT A 1 V66 K68 I95 F113 E114 H115 V116 N118 M163 I174 D175 V65 K67 I94 F112 E113 H114 V115 N117 M162 I173 D174 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMG 3wmb A 2.70 BS01 NF1 A 1 V327 D367 W424 W448 Y475 V484 W490 V305 D345 W402 W426 Y453 V462 W468 3.2.1.52 Q06GJ0 25155420 EDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTLHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERFVRMGIQAESLQPEWCYQNEGYCYS 3wmb A 2.70 BS02 NAG A 1 N375 Q381 L391 N353 Q359 L369 3.2.1.52 Q06GJ0 25155420 EDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTLHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERFVRMGIQAESLQPEWCYQNEGYCYS 3wmc A 2.10 BS01 NF6 A 1 V327 D367 E368 W424 W448 Y475 W490 W524 V305 D345 E346 W402 W426 Y453 W468 W502 3.2.1.52 Q06GJ0 25155420 EDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTLHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERFVRMGIQAESLQPEWCYQNEGYCYS 3wmc A 2.10 BS02 NAG A 1 Y132 R154 N164 T166 Y110 R132 N142 T144 3.2.1.52 Q06GJ0 25155420 EDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTLHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERFVRMGIQAESLQPEWCYQNEGYCYS 3wmc A 2.10 BS03 NAG A 2 N375 Q381 L391 D392 K393 N353 Q359 L369 D370 K371 3.2.1.52 Q06GJ0 25155420 EDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTLHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERFVRMGIQAESLQPEWCYQNEGYCYS 3wxq A 1.60 BS01 STE A 1 L24 T54 F58 K59 T61 D77 R79 L116 R127 Y129 L24 T54 F58 K59 T61 D77 R79 L116 R127 Y129 P05413 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 4cbq A 1.94 BS01 NDP A 1 G160 G161 D162 A163 E166 H182 R183 R184 R188 I246 G158 G159 D160 A161 E164 H180 R181 R182 R186 I244 1.8.1.9 C4LW95 NIHDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGVAAGGQLTTTTIIENFPGFPNGIDGNELMMNMRTQSEKYGTTIITETIDHVDFSTQPFKLFTEEGKEVLTKSVIIATGATAKRMHVPGEDKYWQNGVSACAICDGAVPIFRNKVLMVVGGGDAAMEEALHLTKYGSKVIILHRRDAFRASKTMQERVLNHPKIEVIWNSELVELEGDGDLLNGAKIHNLVSGEYKVVPVAGLFYAIGHSPNSKFLGGQVKTADDGYILTEGPKTSVDGVFACGDVCDRVYRQAIVAAGSGCMAALSCEKWLQTH 4cbq B 1.94 BS01 NDP B 1 K122 G160 G161 D162 A163 H182 R183 R184 R188 A245 I246 H248 Y290 R291 Q292 K120 G158 G159 D160 A161 H180 R181 R182 R186 A243 I244 H246 Y288 R289 Q290 1.8.1.9 C4LW95 NIHDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGVAAGGQLTTTTIIENFPGFPNGIDGNELMMNMRTQSEKYGTTIITETIDHVDFSTQPFKLFTEEGKEVLTKSVIIATGATAKRMHVPGEDKYWQNGVSACAICDGAVPIFRNKVLMVVGGGDAAMEEALHLTKYGSKVIILHRRDAFRASKTMQERVLNHPKIEVIWNSELVELEGDGDLLNGAKIHNLVSGEYKVVPVAGLFYAIGHSPNSKFLGGQVKTADDGYILTEGPKTSVDGVFACGDVCDRVYRQAIVAAGSGCMAALSCEKWLQTH 4cci A 1.30 BS01 CA A 1 D464 G466 D474 Q479 D114 G116 D124 Q129 Q5HKE8 IPPTTVKGRDNYDFYGRVDIESNPTDLNATNLTRYNYGQPPGTTTAGAVQFKNQVSFDKDFDFNIRVANNRQSNTTGADGWGFMFSKKDGDDFLKNGGILREKGTPSAAGFRIDTGYYNNDPLDKIQKQAGQGYRGYGTFVKNDSQGNTSKVGSGTPSTDFLNYADNTTNDLDGKFHGQKLNNVNLKYNASNQTFTATYAGKTWTATLSELGLSPTDSYNFLVTSSQYGNGNSGTYASGVMRADLDGATLTYTPK 4ccr A 2.28 BS01 FAD A 1 I10 G11 S12 G13 P14 A15 Y33 E34 G35 A38 V41 A42 G45 Q46 L47 T50 I53 N55 T87 I88 T117 G118 W133 C143 G283 D284 R291 Q292 A293 I9 G10 S11 G12 P13 A14 Y32 E33 G34 A37 V40 A41 G44 Q45 L46 T49 I52 N54 T86 I87 T116 G117 W132 C142 G280 D281 R288 Q289 A290 1.8.1.9 C4LW95 SNIHDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGVAAGGQLTTTTIIENFPGFPNGIDGNELMMNMRTQSEKYGTTIITETIDHVDFSTQPFKLFTEEGKEVLTKSVIIATGATAKRMHVPGEDKYWQNGVSACAICDGAVPIFRNKVLMVVGGGDAAMEEALHLTKYGSKVIILHRRDAFRKTMQERVLNHPKIEVIWNSELVELEGDGDLLNGAKIHNLVSGEYKVVPVAGLFYAIGHSPNSKFLGGQVKTADDGYILTEGPKTSVDGVFACGDVCDRVYRQAIVAAGSGCMAALSCEKWLQTH 4ccr B 2.28 BS01 FAD B 1 I10 G11 S12 G13 P14 A15 Y33 E34 G35 A38 V41 A42 G45 Q46 L47 T50 N55 I88 A116 T117 G118 W133 C143 G283 D284 R291 Q292 A293 A296 I8 G9 S10 G11 P12 A13 Y31 E32 G33 A36 V39 A40 G43 Q44 L45 T48 N53 I86 A114 T115 G116 W131 C141 G281 D282 R289 Q290 A291 A294 1.8.1.9 C4LW95 NIHDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGVAAGGQLTTTTIIENFPGFPNGIDGNELMMNMRTQSEKYGTTIITETIDHVDFSTQPFKLFTEEGKEVLTKSVIIATGATAKRMHVPGEDKYWQNGVSACAICDGAVPIFRNKVLMVVGGGDAAMEEALHLTKYGSKVIILHRRDAFRASKTMQERVLNHPKIEVIWNSELVELEGDGDLLNGAKIHNLVSGEYKVVPVAGLFYAIGHSPNSKFLGGQVKTADDGYILTEGPKTSVDGVFACGDVCDRVYRQAIVAAGSGCMAALSCEKWLQTH 4ccr D 2.28 BS01 FAD D 1 I10 G11 S12 G13 P14 A15 Y33 E34 G35 A38 V41 A42 G45 Q46 L47 T50 N55 T87 I88 T117 G118 A119 G283 D284 R291 Q292 A293 A296 I9 G10 S11 G12 P13 A14 Y32 E33 G34 A37 V40 A41 G44 Q45 L46 T49 N54 T86 I87 T116 G117 A118 G160 D161 R168 Q169 A170 A173 1.8.1.9 C4LW95 SNIHDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGVAAGGQLTTTTIIENFPGFPNGIDGNELMMNMRTQSEKYGTTIITETIDHVDFSTQPFKLFTEEGKEVLTKSVIIATGATAKAIGHSPNSKFLGGQVKTADDGYILTEGPKTSVDGVFACGDVCDRVYRQAIVAAGSGCMAALSCEKWLQTH 4clm B 1.40 BS01 WPL B 1 S21 E46 R48 R82 K170 M203 M205 R213 F225 S232 A233 Q236 S20 E45 R47 R81 K169 M202 M204 R212 F224 S231 A232 Q235 4.2.1.10 P24670 KTVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDILEWRVDHFMDIASTQSVLTAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNRAAIDSGLVDMIDLELFTGDADVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRKMQALGADIPKIAVMPQSKHDVLTLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEVFGSAATFGAVKQASAPGQIAVNDLRSVLMILHNA 4mtd A 2.50 BS01 NUC Y 1 Y45 P61 Y64 K78 N83 Y85 Y42 P58 Y61 K75 N80 Y82 P0AC51 TTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mtd A 2.50 BS02 NUC Z 1 R23 T25 Q27 R28 Q57 K59 P61 R65 R20 T22 Q24 R25 Q54 K56 P58 R62 P0AC51 TTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mtd A 2.50 BS03 ZN A 1 C103 C106 C143 C146 C100 C103 C140 C143 P0AC51 TTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mtd A 2.50 BS04 ZN A 2 H77 C88 H96 E111 H74 C85 H93 E108 P0AC51 TTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mtd B 2.50 BS01 NUC Y 1 T25 Q27 R28 Q57 K59 P61 R65 T23 Q25 R26 Q55 K57 P59 R63 P0AC51 KTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mtd B 2.50 BS02 NUC Z 1 Y45 P60 P61 Y64 K78 Y85 Y43 P58 P59 Y62 K76 Y83 P0AC51 KTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mtd C 2.50 BS01 NUC Y 1 Y45 P61 Y64 R65 K78 Y85 Y41 P57 Y60 R61 K74 Y81 P0AC51 TTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mtd D 2.50 BS01 NUC Y 1 R23 T25 Q27 R28 Q57 P61 R65 R22 T24 Q26 R27 Q56 P60 R64 P0AC51 EKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mte A 2.50 BS01 NUC Y 1 Y45 Y64 K78 Y85 Y42 Y61 K75 Y82 P0AC51 TTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mte B 2.50 BS02 NUC Z 1 Y45 P61 Y64 K78 Y85 Y43 P59 Y62 K76 Y83 P0AC51 KTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4mte C 2.50 BS01 NUC Y 1 R23 Y45 P61 Y64 R65 K78 N83 Y85 R19 Y41 P57 Y60 R61 K74 N79 Y81 P0AC51 TTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEAC 4nh4 A 2.10 BS01 NAP A 1 P60 M143 T147 G171 A172 V173 A192 G193 K197 Y213 N237 V238 C259 G260 I262 S263 Y265 F289 L290 V291 L334 G337 N339 P54 M137 T141 G165 A166 V167 A186 G187 K191 Y207 N231 V232 C253 G254 I256 S257 Y259 F283 L284 V285 L328 G331 N333 VVVVNKQVLLKHFIPEGAPKETDMELVTTGTIRLRVPEGSNAVLLKNLYLSCDPYMRMRMTKHEEASYVDDFVPGAPITGFGVGKVVDSSHPDFKTGDYVWGLIGWEEYSLITKPQGLFKIHHTEIPLSYYTGILGMVGLTAYVGFYDICSPKKGERVFVSAAAGAVGQIVGQFAKQFGCYVVGSAGSDEKVNLLKTKFGFDEAFNYKKEPDLTKALKRYFPEGIDIYFENVGGPMLEAVLHNMRIKGRIAACGMISQYNLEKPEGVHNLFLIVGKRIRLEGFLVFDHYGSYPEFEEKVVQLIKEEKIKYLEDIVEGLENAPAALIGLFEGRNVGKQVVVVSREKGHHHHHH 4o4g A 2.71 BS01 2RT A 1 L100 K101 K103 V106 V179 Y181 Y188 F227 L234 H235 P236 Y318 L102 K103 K105 V108 V181 Y183 Y190 F229 L236 H237 P238 Y320 2.7.7.49 P03366 24726448 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLV 4o4r A 2.40 BS01 20V A 1 M219 M221 Y341 L391 R392 R393 Q414 K419 M216 M218 Y338 L384 R385 R386 Q407 K412 S4V9Y7 24657439 RPSGTYAGLPIADYGDAPPLSTKTMFWRTSPEKLPPGAWEPAYLGSKDERVDGPSLQQVMRDQLKPYSEPRGLLPPQEILDAVCDAIENRLENTLEPQKPWTFKKACESLDKNTSSGYPYHKQKSKDWTGSAFIGDLGDQATHANNMYEMGKSMRPIYTAALKDELVKPDKIYGKIKKRLLWGSDLGTMIRAARAFGPFCDALKETCIFNPIRVGMSMNEDGPFIFARHANFRYHMDADYTRWDSTQQRAILKRAGDIMVRLSPEPDLARVVMDDLLAPSLLDVGDYKIVVEEGLPSGCPCTTQLNSLAHWILTLCAMVEVTRVDPDIVMQESEFSFYGDDEVVSTNLELDMVKYTMALRRYGLLPTRADPLERRQTLQGISFLRRAIVGDQFGWYGRLDRASIDRQLLWTKGPNHQNPFETLPGHAQRPSQLMALLGEAAMHGEKYYRTVASRVSKEAAQVVPRHRSVLRWVRFG 4o4r A 2.40 BS02 20V A 2 F29 K166 L169 Y341 R392 S410 R413 Q414 K419 F26 K163 L166 Y338 R385 S403 R406 Q407 K412 S4V9Y7 24657439 RPSGTYAGLPIADYGDAPPLSTKTMFWRTSPEKLPPGAWEPAYLGSKDERVDGPSLQQVMRDQLKPYSEPRGLLPPQEILDAVCDAIENRLENTLEPQKPWTFKKACESLDKNTSSGYPYHKQKSKDWTGSAFIGDLGDQATHANNMYEMGKSMRPIYTAALKDELVKPDKIYGKIKKRLLWGSDLGTMIRAARAFGPFCDALKETCIFNPIRVGMSMNEDGPFIFARHANFRYHMDADYTRWDSTQQRAILKRAGDIMVRLSPEPDLARVVMDDLLAPSLLDVGDYKIVVEEGLPSGCPCTTQLNSLAHWILTLCAMVEVTRVDPDIVMQESEFSFYGDDEVVSTNLELDMVKYTMALRRYGLLPTRADPLERRQTLQGISFLRRAIVGDQFGWYGRLDRASIDRQLLWTKGPNHQNPFETLPGHAQRPSQLMALLGEAAMHGEKYYRTVASRVSKEAAQVVPRHRSVLRWVRFG 4o4r B 2.40 BS01 20V B 1 M219 M221 Y341 L391 R392 R393 L406 Q414 K419 M218 M220 Y340 L389 R390 R391 L404 Q412 K417 S4V9Y7 24657439 LPRPSGTYAGLPIADYGDAPPLSTKTMFWRTSPEKLPPGAWEPAYLGSKDERVDGPSLQQVMRDQLKPYSEPRGLLPPQEILDAVCDAIENRLENTLEPQKPWTFKKACESLDKNTSSGYPYHKQKSKDWTGSAFIGDLGDQATHANNMYEMGKSMRPIYTAALKDELVKPDKIYGKIKKRLLWGSDLGTMIRAARAFGPFCDALKETCIFNPIRVGMSMNEDGPFIFARHANFRYHMDADYTRWDSTQQRAILKRAGDIMVRLSPEPDLARVVMDDLLAPSLLDVGDYKIVVEEGLPSGCPCTTQLNSLAHWILTLCAMVEVTRVDPDIVMQESEFSFYGDDEVVSTNLELDMVKYTMALRRYGLLPTRADKEGPLERRQTLQGISFLRRAIVGDQFGWYGRLDRASIDRQLLWTKGPNHQNPFETLPGRPSQLMALLGEAAMHGEKYYRTVASRVSKEAAQSGVVPRHRSVLRWVRFG 4o4r B 2.40 BS02 20V B 2 M28 F29 L169 Y341 L391 R392 S410 R413 Q414 K419 M27 F28 L168 Y340 L389 R390 S408 R411 Q412 K417 S4V9Y7 24657439 LPRPSGTYAGLPIADYGDAPPLSTKTMFWRTSPEKLPPGAWEPAYLGSKDERVDGPSLQQVMRDQLKPYSEPRGLLPPQEILDAVCDAIENRLENTLEPQKPWTFKKACESLDKNTSSGYPYHKQKSKDWTGSAFIGDLGDQATHANNMYEMGKSMRPIYTAALKDELVKPDKIYGKIKKRLLWGSDLGTMIRAARAFGPFCDALKETCIFNPIRVGMSMNEDGPFIFARHANFRYHMDADYTRWDSTQQRAILKRAGDIMVRLSPEPDLARVVMDDLLAPSLLDVGDYKIVVEEGLPSGCPCTTQLNSLAHWILTLCAMVEVTRVDPDIVMQESEFSFYGDDEVVSTNLELDMVKYTMALRRYGLLPTRADKEGPLERRQTLQGISFLRRAIVGDQFGWYGRLDRASIDRQLLWTKGPNHQNPFETLPGRPSQLMALLGEAAMHGEKYYRTVASRVSKEAAQSGVVPRHRSVLRWVRFG 4o5q A 2.00 BS01 FAD A 1 V218 G219 G221 P222 A223 G242 E243 R244 G247 Q248 T252 N257 Q288 S289 A290 A321 T322 G323 W326 C348 N454 G487 D488 K495 Q496 I497 A500 V218 G219 G221 P222 A223 G242 E243 R244 G247 Q248 T252 N257 Q288 S289 A290 A321 T322 G323 W326 C348 N454 G487 D488 K495 Q496 I497 A500 P35340 MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIAELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPSKEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQNEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIVGSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNMNVPGEDQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKADQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKASLSAFDYLIRTKTA 4o5v A 2.10 BS01 FE2 A 1 E86 C128 H130 E166 E81 C123 H125 E161 Q9HJU1 24816097 IRSVTEEDYLKIIQELVLYKGYATLADISRSLNVKRQSVRDEINHLISLSMAEKIERGKYRLTPSGDREANRFLRKHRTAEILLSRCIGIPWERVDEEAMGIEHGMTEEIIQRTIERFGVDRCPHGNPIPDPEGNVEPVADVRITSLLPDSTARISRIVYETDDILHFLALNGLIPGKDIKIESVKDTVRVLVDGRSIEIPTDIAMAIMVTVD 4oka A 2.50 BS01 5IR A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 S88 T90 W92 W108 L110 K112 L124 D128 N11 L13 S15 Y31 S33 V35 G36 N37 W67 S76 T78 W80 W96 L98 K100 L112 D116 P22629 25317660 DEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTKGTTEANAWKSTLVGHDTFTKVK 4ou3 A 1.95 BS01 III B 1 Q208 S209 N345 A346 G347 A348 M349 E350 H383 E384 E406 S464 F467 Y472 Q146 S147 N283 A284 G285 A286 M287 E288 H321 E322 E344 S402 F405 Y410 3.4.11.2 P15145 QSKPWNRYRLPTTLLPDSYNVTLRPYLTPNADGLYIFKGKSIVRFLCQEPTDVIIIHSKKLNYTTQGHMVVLRGVGDSQVPEIDRTELVELTEYLVVHLKGSLQPGHMYEMESEFQGELADDLAGFYRSEYMEGNVKKVLATTQMQSTDARKSFPCFDEPAMKATFNITLIHPNNLTALSNMPPKGSSTPLAEDPNWSVTEFETTPVMSTYLLAYIVSEFQSVNETAQNGVLIRIWARPNAIAEGHGMYALNVTGPILNFFANHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYRENALLFDPQSSSISNKERVVTVIAHELAHQWFGNLVTLAWWNDLWLNEGFASYVEYLGADHAEPTWNLKDLIVPGDVYRVMAVDALASSHPLTTPAEEVNTPAQISEMFDSISYSKGASVIRMLSNFLTEDLFKEGLASYLHAFAYQNTTYLDLWEHLQKAVDAQTSIRLPDTVRAIMDRWTLQMGFPVITVDTKTGNISQKHFLLDSESNVTRSSAFDYLWIVPISSIKNGVMQDHYWLRDVSQAQNDLFKTASDDWVLLNVNVTGYFQVNYDEDNWRMIQHQLQTNLSVIPVINRAQVIYDSFNLATAHMVPVTLALDNTLFLNGEKEYMPWQAALSSLSYFSLMFDRSEVYGPMKKYLRKQVEPLFQHFETLTKNWTERPENLMDQYSEINAISTACSNGLPQCENLAKTLFDQWMSDPENNPIHPNLRSTIYCNAIAQGGQDQWDFAWGQLQQAQLVNEADKLRSALACSNEVWLLNRYLGYTLNPDLIRKQDATSTINSIASNVIGQPLAWDFVQSNWKKLFQDYGGGSFSFSNLIQGVTRRFSSEFELQQLEQFKKNNMDVGFGSGTRALEQALEKTKANIKWVKENKEVVLNWFIEHSS 4ovb A 2.03 BS01 AUC A 1 S104 H107 V116 P117 R140 S104 H107 V116 P117 R140 P29772 MLLWRRCRAWLEIRRLDKELAQSSGLPLELPQIVPNAWNEVVWRLPVPNHPDAFMTASNAAQSDFIVYVNGLAFYRAWLALGVEDSQACPLKQDMPKDRKYPSSAAHFAVGIDSPVPLADVSPTMILGHFAVCFTDGMTRSMWLLAHEVAVFPVLSRDEASAVMLAEHVGVAAPIQVSKLREQCRKIL 4ovb A 2.03 BS02 AUC A 2 I175 L180 Q183 I175 L180 Q183 P29772 MLLWRRCRAWLEIRRLDKELAQSSGLPLELPQIVPNAWNEVVWRLPVPNHPDAFMTASNAAQSDFIVYVNGLAFYRAWLALGVEDSQACPLKQDMPKDRKYPSSAAHFAVGIDSPVPLADVSPTMILGHFAVCFTDGMTRSMWLLAHEVAVFPVLSRDEASAVMLAEHVGVAAPIQVSKLREQCRKIL 4ovb A 2.03 BS03 AUC A 3 P31 I33 W43 Y68 P31 I33 W43 Y68 P29772 MLLWRRCRAWLEIRRLDKELAQSSGLPLELPQIVPNAWNEVVWRLPVPNHPDAFMTASNAAQSDFIVYVNGLAFYRAWLALGVEDSQACPLKQDMPKDRKYPSSAAHFAVGIDSPVPLADVSPTMILGHFAVCFTDGMTRSMWLLAHEVAVFPVLSRDEASAVMLAEHVGVAAPIQVSKLREQCRKIL 4pe0 X 1.08 BS01 NQS X 1 F43 L44 A83 C84 F88 F44 L45 A84 C85 F89 P02638 25268459 MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFF 4pe0 A 1.08 BS01 NQS A 1 F43 A83 C84 F87 F88 F44 A84 C85 F88 F89 P02638 25268459 MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFEHE 4pnj A 1.36 BS01 HEM A 1 L32 T39 K42 F43 R45 H64 T67 V68 A71 L72 L89 S92 H93 H97 I99 Y103 L104 I107 L33 T40 K43 F44 R46 H65 T68 V69 A72 L73 L90 S93 H94 H98 I100 Y104 L105 I108 P02185 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG 4ppr A 2.00 BS01 MER A 1 A120 S121 T153 S176 N178 G217 L218 K282 T283 G284 Y285 T286 Q291 R313 A62 S63 T95 S118 N120 G159 L160 K224 T225 G226 Y227 T228 Q233 R255 O53380 PLPLVVPPTPVGGNALGGCGIITAPGSAPAPGDVSAEAWLVADLDSGAVIAARDPHGRHRPASVIKVLVAMASINTLTLNKSVAGTADDAAVEGTKVGVNTGGTYTVNQLLHGLLMHSGNDAAYALARQLGGMPAALEKINLLAAKLGGRDTRVATPSGLDGPGMSTSAYDIGLFYRYAWQNPVFADIVATRTFDFPGHGDHPGYELENDNQLLYNYPGALGGKTGYTDDAGQTFVGAANRDGRRLMTVLLHGTRQPIPPWEQAAHLLDYGFNTPAGTQIGTLIEPDPSLMSTDRRVDPQ 4q18 A 2.00 BS01 2XJ A 1 E53 V55 L82 M85 Y86 P89 F96 Q97 R128 D133 F137 S144 S146 Y204 E33 V35 L52 M55 Y56 P59 F66 Q67 R98 D103 F107 S114 S116 Y174 2.7.1.74 P27707 25341194 IKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNLTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q18 A 2.00 BS02 2XJ A 2 I30 S59 Y86 E196 E197 G199 I200 P201 Y204 I10 S39 Y56 E166 E167 G169 I170 P171 Y174 2.7.1.74 P27707 25341194 IKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNLTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q18 B 2.00 BS02 2XJ B 1 E53 V55 L82 M85 P89 F96 Q97 R128 D133 F137 N140 L141 S144 Y204 K207 E35 V37 L53 M56 P60 F67 Q68 R99 D104 F108 N111 L112 S115 Y175 K178 2.7.1.74 P27707 25341194 TRIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSLTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q18 B 2.00 BS03 2XJ B 2 I30 S59 L82 Y86 R194 E196 E197 G199 I200 P201 Y204 I12 S41 L53 Y57 R165 E167 E168 G170 I171 P172 Y175 2.7.1.74 P27707 25341194 TRIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSLTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q19 A 2.09 BS01 2XL A 1 I30 E53 V55 L82 M85 Y86 P89 Q97 R128 D133 F137 Y204 I10 E33 V35 L51 M54 Y55 P58 Q66 R96 D101 F105 Y172 2.7.1.74 P27707 25341194 IKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSLTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q1c B 2.00 BS01 2XM B 1 E53 V55 L82 Y86 P89 Q97 R128 D133 F137 L141 S144 Y204 E34 V36 L51 Y55 P58 Q66 R97 D102 F106 L110 S113 Y173 2.7.1.74 P27707 25341194 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q1e A 1.85 BS01 2Y8 A 1 E53 V55 L82 M85 P89 F96 Q97 R128 D133 F137 N140 L141 S144 S146 Y204 E34 V36 L53 M56 P60 F67 Q68 R99 D104 F108 N111 L112 S115 S117 Y175 2.7.1.74 P27707 25341194 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNLTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q1f A 2.10 BS02 2XN A 1 I30 E53 V55 L82 M85 Y86 P89 F96 Q97 R128 D133 F137 N140 L141 S144 Y204 K207 I11 E34 V36 L53 M56 Y57 P60 F67 Q68 R99 D104 F108 N111 L112 S115 Y175 K178 2.7.1.74 P27707 25341194 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNLTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q1f B 2.10 BS02 2XN B 1 E53 L82 M85 Y86 P89 F96 Q97 R128 D133 F137 S144 P201 Y204 E34 L53 M56 Y57 P60 F67 Q68 R99 D104 F108 S115 P172 Y175 2.7.1.74 P27707 25341194 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNLTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q4w 1 1.40 BS01 CA 1 1 T26 A27 Q28 S29 N68 T2 A3 Q4 S5 N44 V9VEF3 25329320 PTAQSTPLTSGVNSQEVPALTAVETGASGQAVPSDVIETRHVVNYKTRSESTLESFFGRSACVTILEVENFNATTDADRKKQFTTWAITYTDTVQLRRKLEFFTYSRFDLEMTFVITERYYASNTGHARNQVYQLMYIPPGAPRPTAWDDYTWQSSSNPSVFYTYGSAPPRMSIPYVGIANAYSHFYDGFARVPLKDETVDSGDTYYGLVTINDFGTLAVRVVNEYNPARITSKIRVYMKPKHVRCWCPRPPRAVPYRGEGVDFKQDSITPLTAVENINTF 4q4w 1 1.40 BS02 CA 1 2 T33 S34 S58 I61 T9 S10 S34 I37 V9VEF3 25329320 PTAQSTPLTSGVNSQEVPALTAVETGASGQAVPSDVIETRHVVNYKTRSESTLESFFGRSACVTILEVENFNATTDADRKKQFTTWAITYTDTVQLRRKLEFFTYSRFDLEMTFVITERYYASNTGHARNQVYQLMYIPPGAPRPTAWDDYTWQSSSNPSVFYTYGSAPPRMSIPYVGIANAYSHFYDGFARVPLKDETVDSGDTYYGLVTINDFGTLAVRVVNEYNPARITSKIRVYMKPKHVRCWCPRPPRAVPYRGEGVDFKQDSITPLTAVENINTF 4q4w 1 1.40 BS03 CA 1 3 V41 L44 V17 L20 V9VEF3 25329320 PTAQSTPLTSGVNSQEVPALTAVETGASGQAVPSDVIETRHVVNYKTRSESTLESFFGRSACVTILEVENFNATTDADRKKQFTTWAITYTDTVQLRRKLEFFTYSRFDLEMTFVITERYYASNTGHARNQVYQLMYIPPGAPRPTAWDDYTWQSSSNPSVFYTYGSAPPRMSIPYVGIANAYSHFYDGFARVPLKDETVDSGDTYYGLVTINDFGTLAVRVVNEYNPARITSKIRVYMKPKHVRCWCPRPPRAVPYRGEGVDFKQDSITPLTAVENINTF 4q4w 4 1.40 BS01 CA 1 4 K63 A65 K51 A53 V9VEF3 25329320 GAQVSSQKVGAHVNYTTINYYKDSASNAASKLDFSQDPSKFTEPVKDIMIKTAPALN 4q4x 1 1.65 BS01 SIA 1 1 Y145 A146 S147 Y121 A122 S123 V9VEF3 25329320 PTAQSTPLTSGVNSQEVPALTAVETGASGQAVPSDVIETRHVVNYKTRSESTLESFFGRSACVTILEVENFNATTDADRKKQFTTWAITYTDTVQLRRKLEFFTYSRFDLEMTFVITERYYASNTGHARNQVYQLMYIPPGAPRPTAWDDYTWQSSSNPSVFYTYGSAPPRMSIPYVGIANAYSHFYDGFARVPLKDETVDSGDTYYGLVTINDFGTLAVRVVNEYNPARITSKIRVYMKPKHVRCWCPRPPRAVPYRGEGVDFKQDSITPLTAVENINTF 4q4x 1 1.65 BS04 CA 1 3 N94 W172 V246 N248 N70 W148 V222 N224 V9VEF3 25329320 PTAQSTPLTSGVNSQEVPALTAVETGASGQAVPSDVIETRHVVNYKTRSESTLESFFGRSACVTILEVENFNATTDADRKKQFTTWAITYTDTVQLRRKLEFFTYSRFDLEMTFVITERYYASNTGHARNQVYQLMYIPPGAPRPTAWDDYTWQSSSNPSVFYTYGSAPPRMSIPYVGIANAYSHFYDGFARVPLKDETVDSGDTYYGLVTINDFGTLAVRVVNEYNPARITSKIRVYMKPKHVRCWCPRPPRAVPYRGEGVDFKQDSITPLTAVENINTF 4q4x 3 1.65 BS01 CA 3 1 T4 L6 T4 L6 V9VEF3 25329320 GLPTMLTPGSSQFLTSDDFQSPCALPNFDVTPPIHIPGEVFNMMELAEIDSMIPMNSVTGKANTMEMYPIPLDDKGSATPIFSISLSPASDKRLQYTMLGEILNYYTHWTGSLRFTFLFCGSMMATGKILLSYSPPGAKPPTTRKDAMLGTHIIWDLGLQSSCTMLAPWISNTVYRRCIKDDFTEGGYITCFYQTRIVVPSGTPTSMFMLAFVSACPDFSVRLLRDTNHISQRT 4q4y 1 1.88 BS02 CA 1 1 T33 S34 S58 I61 E62 T9 S10 S34 I37 E38 V9VEF3 25329320 PTAQSTPLTSGVNSQEVPALTAVETGASGQAVPSDVIETRHVVNYKTRSESTLESFFGRSACVTILEVENFNATTDADRKKQFTTWAITYTDTVQLRRKLEFFTYSRFDLEMTFVITERYYASNTGHARNQVYQLMYIPPGAPRPTAWDDYTWQSSSNPSVFYTYGSAPPRMSIPYVGIANAYSHFYDGFARVPLKDETVDSGDTYYGLVTINDFGTLAVRVVNEYNPARITSKIRVYMKPKHVRCWCPRPPRAVPYRGEGVDFKQDSITPLTAVENINTF 4q6m A 1.60 BS01 CA A 1 Q46 E49 H128 Q25 E28 H107 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6m A 1.60 BS02 CA A 2 N382 V383 F386 E396 N361 V362 F365 E375 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6m A 1.60 BS03 CA A 3 H62 D254 H41 D233 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6n A 1.55 BS01 MHI A 1 R86 N93 R94 H126 H128 G130 G131 W148 M203 A206 L207 T208 A220 E222 R65 N72 R73 H105 H107 G109 G110 W127 M182 A185 L186 T187 A199 E201 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6n A 1.55 BS02 CA A 1 Q46 E49 R86 H128 Q25 E28 R65 H107 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6o A 1.41 BS04 API A 1 N93 R94 H126 H128 W148 M203 A206 L207 T208 A220 E222 N72 R73 H105 H107 W127 M182 A185 L186 T187 A199 E201 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6p A 2.62 BS03 ZN A 3 Q320 E321 Q299 E300 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6p A 2.62 BS04 ZN A 4 E188 H190 E167 H169 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6p A 2.62 BS06 API A 1 N93 R94 H126 H128 W148 M203 T208 E222 N72 R73 H105 H107 W127 M182 T187 E201 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6q A 2.40 BS02 CA A 1 L229 K329 L208 K308 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q6q A 2.40 BS03 CA A 2 N173 E176 N152 E155 O25708 MIEKAPTNVEDRDKAPHLLLLAGIQGDEPGGFNATNLFLMHYSVLKGLVEVVPVLNKPSMLRNHRGLYGDMNRKFAALDKNDPEYPTIQEIKSLIAKPSIDAVLHLHDGGGYYRPVYVDAMLNPKRWGNCFIIDQDEVKGAKFPNLLAFANNTIESINAHLLHPIEEYHLKNTRTAQGDTEMQKALTFYAINQKKSAFANEASKELPLASRVFYHLQAIEGLLNQLNIPFKRDFDLNPNSVHALINDKNLWAKISSLPKMPLFNLRPKLNHFPLPHNTKIPQIPIESNAYIVGLVKNKQEVFLKYGNKLMTRLSPFYIEFDPSLEEVKMQIDNKDQMVKIGSVVEVKESFYIHAMDNIRANVIGFSVSNENKPNEAGYTIKFKDFQKRFSLDKQERIYRIEFYKNNAFSGMILVKFV 4q8r A 1.65 BS01 PO4 A 1 S11 T12 S13 G40 S41 S59 R125 S129 G130 T131 S7 T8 S9 G36 S37 S55 R121 S125 G126 T127 Q0TTH0 25338617 SVSISGSTSVGPVMEAEAEAFKTKKPDVSIEINQIGSSAGIKNAMEGVSEIGMASRDLKGEEKQAGLKEVEIAYDGIALITHKNNPVKDLTLVQIKDIYTGKITNWKELGGNDAPIVVVSREDGSGTRDAFQEIVGFKAEELTVNSQISDGSGNIKSLVQGNENAIGYISFSYVDDSVSAVKVDGVEATPENVLNKSYKVSRPFLAVYKEENLTESGKSFIDFILSEEGQDIVAKEHLIKV 4q8r A 1.65 BS02 ZN A 1 E231 D235 E227 D231 Q0TTH0 25338617 SVSISGSTSVGPVMEAEAEAFKTKKPDVSIEINQIGSSAGIKNAMEGVSEIGMASRDLKGEEKQAGLKEVEIAYDGIALITHKNNPVKDLTLVQIKDIYTGKITNWKELGGNDAPIVVVSREDGSGTRDAFQEIVGFKAEELTVNSQISDGSGNIKSLVQGNENAIGYISFSYVDDSVSAVKVDGVEATPENVLNKSYKVSRPFLAVYKEENLTESGKSFIDFILSEEGQDIVAKEHLIKV 4q8r A 1.65 BS03 ZN A 2 D61 E73 D57 E69 Q0TTH0 25338617 SVSISGSTSVGPVMEAEAEAFKTKKPDVSIEINQIGSSAGIKNAMEGVSEIGMASRDLKGEEKQAGLKEVEIAYDGIALITHKNNPVKDLTLVQIKDIYTGKITNWKELGGNDAPIVVVSREDGSGTRDAFQEIVGFKAEELTVNSQISDGSGNIKSLVQGNENAIGYISFSYVDDSVSAVKVDGVEATPENVLNKSYKVSRPFLAVYKEENLTESGKSFIDFILSEEGQDIVAKEHLIKV 4qbb A 1.60 BS01 E69 A 1 N46 D49 N50 C51 W52 E96 G97 G98 L143 E147 H148 A149 D163 D164 N18 D21 N22 C23 W24 E68 G69 G70 L115 E119 H120 A121 D135 D136 3.4.22.46 P03305 25240326 MELTLYNGEKKTFYSRPNNHDNCWLNAILQLFRYVEEPFFDWVYSSPENLTLEAIKQLEDLTGLELHEGGPPALVIWNIKHLLHTGIGTASRPSEVCVVDGTDMCLADFHAGIFLKGQEHAVFACVTSNGWYAIDDEDFYPWTPDPSDVLVFVPYDQEP 4qbb B 1.60 BS01 E69 B 1 N46 D49 N50 C51 W52 E96 G97 G98 L143 Q146 E147 H148 A149 N18 D21 N22 C23 W24 E68 G69 G70 L115 Q118 E119 H120 A121 3.4.22.46 P03305 25240326 MELTLYNGEKKTFYSRPNNHDNCWLNAILQLFRYVEEPFFDWVYSSPENLTLEAIKQLEDLTGLELHEGGPPALVIWNIKHLLHTGIGTASRPSEVCVVDGTDMCLADFHAGIFLKGQEHAVFACVTSNGWYAIDDEDFYPWTPDPSDVLVFVPYD 4qbb C 1.60 BS01 E69 C 1 N46 D49 N50 C51 W52 E96 G97 G98 P100 L143 E147 H148 A149 N18 D21 N22 C23 W24 E68 G69 G70 P72 L115 E119 H120 A121 3.4.22.46 P03305 25240326 MELTLYNGEKKTFYSRPNNHDNCWLNAILQLFRYVEEPFFDWVYSSPENLTLEAIKQLEDLTGLELHEGGPPALVIWNIKHLLHTGIGTASRPSEVCVVDGTDMCLADFHAGIFLKGQEHAVFACVTSNGWYAIDDEDFYPWTPDPSDVLVFVPYDQ 4qty A 1.60 BS02 AZI A 1 K53 G66 T67 D68 V69 K25 G38 T39 D40 V41 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETHKIPVAADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHH 4qu0 A 1.95 BS02 AZI A 1 K53 G66 T67 D68 K25 G38 T39 D40 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETHKIPVEADFLAAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIHSMLTKELYFYHH 4qu9 A 1.56 BS02 AZI A 1 K88 N89 K60 N61 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIAGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHLH 4qu9 A 1.56 BS03 AZI A 2 E106 R111 E78 R83 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIAGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHLH 4qu9 A 1.56 BS04 AZI A 3 N73 C220 A221 N45 C181 A182 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIAGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHLH 4qu9 A 1.56 BS05 AZI A 4 D253 A254 D214 A215 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIAGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHLH 4qub A 1.69 BS02 AZI A 1 E43 E84 E15 E56 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLAKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHHH 4qub A 1.69 BS03 AZI A 2 N73 A221 N45 A182 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLAKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHHH 4qub A 1.69 BS04 AZI A 3 L136 A137 T140 Y195 L108 A109 T112 Y156 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLAKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHHH 4qub A 1.69 BS06 AZI A 5 K229 L230 E231 H234 K190 L191 E192 H195 3.4.22.56 P42574 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLAKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHHH 4qud A 2.00 BS01 III D 1 R64 S120 H121 Q161 C163 Y204 S205 W206 R207 N208 S209 W214 S249 F250 F256 R36 S92 H93 Q133 C135 Y166 S167 W168 R169 N170 S171 W176 S211 F212 F218 3.4.22.56 25343534 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKIFNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 4que A 1.84 BS02 III E 1 D68 A72 R75 R86 N87 K88 N89 D35 A39 R42 R53 N54 K55 N56 3.4.22.56 P42574 25343534 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETCHKIPVEADFLFAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIHSMLTKELYFY 4que C 1.84 BS02 III D 1 R75 R86 N87 K88 N89 R42 R53 N54 K55 N56 3.4.22.56 P42574 25343534 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLFAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIHSMLTKELYFY 4qug A 1.92 BS03 AZI A 2 T92 E94 E95 T59 E61 E62 3.4.22.56 P42574 25343534 DNSYKMDYPEMGLCIIINNKNFHKSTGATSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 4quh A 1.76 BS04 AZI A 2 N73 C220 A221 K224 N40 C177 A178 K181 3.4.22.56 25343534 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKIGNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 4quh C 1.76 BS03 AZI C 2 N80 L81 N47 L48 3.4.22.56 P42574 25343534 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKIGNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETCHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 4qul A 1.90 BS02 AZI A 1 K137 T140 N141 E190 F193 K101 T104 N105 E143 F146 3.4.22.56 P42574 25343534 DNSYKMDYPEMGLCIIINNKNWTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 4qul A 1.90 BS03 AZI A 2 N208 D211 W214 Q217 F247 N161 D164 W167 Q170 F200 3.4.22.56 P42574 25343534 DNSYKMDYPEMGLCIIINNKNWTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIEHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 4qwn A 2.10 BS01 III E 1 M111 Q116 G118 I144 S145 N186 A187 I188 M191 Y199 T209 D210 H212 F215 Y222 N298 K323 F324 R325 M76 Q81 G83 I109 S110 N151 A152 I153 M156 Y164 T174 D175 H177 F180 Y187 N263 K288 F289 R290 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qwn A 2.10 BS02 AKG A 1 N142 I144 T209 H212 D214 Y222 K229 H284 V286 N107 I109 T174 H177 D179 Y187 K194 H249 V251 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qwn C 2.10 BS01 III F 1 I144 S145 N186 A187 I188 M191 Y199 F215 Y222 N298 K323 F324 R325 I109 S110 N151 A152 I153 M156 Y164 F180 Y187 N263 K288 F289 R290 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qx7 A 2.34 BS01 III E 1 R36 D109 M111 N114 T115 Q116 K117 I144 S145 N186 A187 I188 M191 Y199 T209 D210 H212 D214 F215 Y222 Q253 G254 N298 K323 F324 R325 R1 D74 M76 N79 T80 Q81 K82 I109 S110 N151 A152 I153 M156 Y164 T174 D175 H177 D179 F180 Y187 Q218 G219 N263 K288 F289 R290 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qx7 A 2.34 BS02 AKG A 1 N142 I144 L201 T209 H212 D214 Y222 K229 H284 V286 N107 I109 L166 T174 H177 D179 Y187 K194 H249 V251 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qx7 C 2.34 BS01 III F 1 D109 M111 I144 S145 N186 A187 I188 M191 Y199 T209 D214 F215 V220 Y222 Q253 N298 T318 R319 V320 K323 F324 R325 D74 M76 I109 S110 N151 A152 I153 M156 Y164 T174 D179 F180 V185 Y187 Q218 N263 T283 R284 V285 K288 F289 R290 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qx8 A 1.65 BS01 III E 1 D109 M111 Q116 G118 I144 S145 N186 A187 I188 M191 Y199 L201 T209 D210 H212 D214 F215 V220 Q253 N298 T318 V320 K323 F324 R325 D74 M76 Q81 G83 I109 S110 N151 A152 I153 M156 Y164 L166 T174 D175 H177 D179 F180 V185 Q218 N263 T283 V285 K288 F289 R290 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qx8 C 1.65 BS01 III F 1 M111 Q116 I144 S145 N186 A187 I188 M191 Y199 L201 T209 D210 H212 F215 V220 Y222 L248 Q253 G297 N298 T318 V320 K323 F324 R325 M76 Q81 I109 S110 N151 A152 I153 M156 Y164 L166 T174 D175 H177 F180 V185 Y187 L213 Q218 G262 N263 T283 V285 K288 F289 R290 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qxb A 1.60 BS01 III E 1 R36 D109 M111 N114 T115 Q116 K117 G118 I144 S145 N186 A187 I188 Y199 L201 T209 D210 H212 D214 F215 V220 Q253 G254 N298 K323 F324 R325 P327 R1 D74 M76 N79 T80 Q81 K82 G83 I109 S110 N151 A152 I153 Y164 L166 T174 D175 H177 D179 F180 V185 Q218 G219 N263 K288 F289 R290 P292 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qxc C 1.75 BS01 III F 1 M111 Q116 I144 S145 N186 A187 I188 M191 Y199 L201 T209 D210 H212 D214 F215 V220 N298 T318 V320 K323 F324 R325 M76 Q81 I109 S110 N151 A152 I153 M156 Y164 L166 T174 D175 H177 D179 F180 V185 N263 T283 V285 K288 F289 R290 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qxh A 2.20 BS01 III E 1 R36 M111 N114 T115 Q116 K117 G118 I144 S145 N186 A187 I188 Y199 T209 D210 H212 D214 F215 Q253 G254 N298 K323 F324 R325 R1 M76 N79 T80 Q81 K82 G83 I109 S110 N151 A152 I153 Y164 T174 D175 H177 D179 F180 Q218 G219 N263 K288 F289 R290 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4qxh C 2.20 BS01 III F 1 M111 Q116 I144 S145 N186 A187 I188 M191 Y199 H212 D214 F215 Q253 N298 T318 V320 K323 F324 R325 M76 Q81 I109 S110 N151 A152 I153 M156 Y164 H177 D179 F180 Q218 N263 T283 V285 K288 F289 R290 1.14.11.27 F6YRW4 25128496 RTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDME 4r3m A 1.80 BS01 JR9 A 1 N51 A55 D93 M98 N106 L107 I110 G135 F138 Y139 V150 W162 T184 N36 A40 D78 M83 N91 L92 I95 G120 F123 Y124 V135 W147 T169 P07900 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 4r4n A 3.56 BS01 III a 1 T257 V281 S365 G366 G367 D368 I371 S375 F376 N425 M426 W427 R429 V430 T455 G472 G473 D474 M475 T136 V160 S223 G224 G225 D226 I229 S233 F234 N266 M267 W268 R270 V271 T296 G313 G314 D315 M316 25165110 NTTLFCASDAKAYDTEVHNVWATHACVPTDPSPQELKMENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVQLTGGSALTQACPKVTFEPIPIHYCAPAGYAILKCNDKEFNGTGLCKNVSTVQCTHGIRPVVSTQLLLNGSLAEGKVMIRSENITNNVKNIIVQLNESVTINCTRPNNSGGDIRQAHCNVSGSQWNKTLHQVVEQLRKYWNNNTIIFNSSSGGDLEITTHSFNCGGEFFYCNTSGLFNSNGTITLPCRIKQIINMWQRVGQAIYAPPIQGVIRCVSNITGLILTRDGGGNSNENETFRPGGGDMRDNWRSELYKYKVVKIE 4r4n E 3.56 BS01 III e 1 T257 S365 G366 G367 D368 E370 I371 S375 F376 N425 M426 W427 V430 G472 G473 M475 T136 S223 G224 G225 D226 E228 I229 S233 F234 N262 M263 W264 V267 G309 G310 M312 25165110 NTTLFCASDAKAYDTEVHNVWATHACVPTDPSPQELKMENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVQLTGGSALTQACPKVTFEPIPIHYCAPAGYAILKCNDKEFNGTGLCKNVSTVQCTHGIRPVVSTQLLLNGSLAEGKVMIRSENITNNVKNIIVQLNESVTINCTRPNNSGGDIRQAHCNVSGSQWNKTLHQVVEQLRKYWNNNTIIFNSSSGGDLEITTHSFNCGGEFFYCNTSGLFNSTLPCRIKQIINMWQRVGQAIYAPPIQGVIRCVSNITGLILTRDGGGNSNENETFRPGGGDMRDNWRSELYKYKVVKIE 4r4n M 3.56 BS01 III m 1 T257 S365 G366 G367 D368 E370 S375 F376 F382 N425 M426 W427 V430 G472 G473 M475 T136 S223 G224 G225 D226 E228 S233 F234 F240 N272 M273 W274 V277 G319 G320 M322 25165110 NTTLFCASDAKAYDTEVHNVWATHACVPTDPSPQELKMENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVQLTGGSALTQACPKVTFEPIPIHYCAPAGYAILKCNDKEFNGTGLCKNVSTVQCTHGIRPVVSTQLLLNGSLAEGKVMIRSENITNNVKNIIVQLNESVTINCTRPNNSGGDIRQAHCNVSGSQWNKTLHQVVEQLRKYWNNNTIIFNSSSGGDLEITTHSFNCGGEFFYCNTSGLFNSGTASIENGTITLPCRIKQIINMWQRVGQAIYAPPIQGVIRCVSNITGLILTRDGGGNSNENETFRPGGGDMRDNWRSELYKYKVVKIE 4r4n P 3.56 BS01 III p 1 S365 G366 G367 D368 E370 I371 S375 F382 N425 M426 W427 R429 T455 G472 D474 S223 G224 G225 D226 E228 I229 S233 F240 N271 M272 W273 R275 T301 G318 D320 25165110 NTTLFCASDAKAYDTEVHNVWATHACVPTDPSPQELKMENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVQLTGGSALTQACPKVTFEPIPIHYCAPAGYAILKCNDKEFNGTGLCKNVSTVQCTHGIRPVVSTQLLLNGSLAEGKVMIRSENITNNVKNIIVQLNESVTINCTRPNNSGGDIRQAHCNVSGSQWNKTLHQVVEQLRKYWNNNTIIFNSSSGGDLEITTHSFNCGGEFFYCNTSGLFNGTASIENGTITLPCRIKQIINMWQRVGQAIYAPPIQGVIRCVSNITGLILTRDGGGNSNENETFRPGGGDMRDNWRSELYKYKVVKIE 4r4n S 3.56 BS01 III s 1 S365 G366 G367 D368 E370 I371 S375 F382 N425 M426 W427 R429 V430 S223 G224 G225 D226 E228 I229 S233 F240 N272 M273 W274 R276 V277 25165110 NTTLFCASDAKAYDTEVHNVWATHACVPTDPSPQELKMENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVQLTGGSALTQACPKVTFEPIPIHYCAPAGYAILKCNDKEFNGTGLCKNVSTVQCTHGIRPVVSTQLLLNGSLAEGKVMIRSENITNNVKNIIVQLNESVTINCTRPNNSGGDIRQAHCNVSGSQWNKTLHQVVEQLRKYWNNNTIIFNSSSGGDLEITTHSFNCGGEFFYCNTSGLFNSGTASIENGTITLPCRIKQIINMWQRVGQAIYAPPIQGVIRCVSNITGLILTRDGGGNSNENETFRPGGGDMRDNWRSELYKYKVVKIE 4r4n V 3.56 BS01 III v 1 S365 G366 G367 D368 E370 I371 S375 F376 F382 N425 M426 W427 R429 V430 T455 G472 G473 M475 S223 G224 G225 D226 E228 I229 S233 F234 F240 N271 M272 W273 R275 V276 T301 G318 G319 M321 25165110 NTTLFCASDAKAYDTEVHNVWATHACVPTDPSPQELKMENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVQLTGGSALTQACPKVTFEPIPIHYCAPAGYAILKCNDKEFNGTGLCKNVSTVQCTHGIRPVVSTQLLLNGSLAEGKVMIRSENITNNVKNIIVQLNESVTINCTRPNNSGGDIRQAHCNVSGSQWNKTLHQVVEQLRKYWNNNTIIFNSSSGGDLEITTHSFNCGGEFFYCNTSGLFNGTASIENGTITLPCRIKQIINMWQRVGQAIYAPPIQGVIRCVSNITGLILTRDGGGNSNENETFRPGGGDMRDNWRSELYKYKVVKIE 4r8p A 3.28 BS02 NUC J 1 H39 R40 Y41 P43 G44 V46 A47 R49 R63 K64 L65 P66 R69 H3 R4 Y5 P7 G8 V10 A11 R13 R27 K28 L29 P30 R33 P84233 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 4r8p D 3.28 BS01 NUC I 1 K31 T32 Y42 G53 I54 S55 S56 R86 S87 T88 K1 T2 Y12 G23 I24 S25 S26 R56 S57 T58 P02281 KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 4r8p E 3.28 BS01 NUC I 1 H39 R40 Y41 P43 G44 T45 V46 A47 R49 K56 R63 K64 L65 P66 R69 R83 H2 R3 Y4 P6 G7 T8 V9 A10 R12 K19 R26 K27 L28 P29 R32 R46 P84233 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 4r8p E 3.28 BS02 NUC J 1 R42 P43 T45 R63 R72 R83 F84 Q85 R116 V117 T118 R5 P6 T8 R26 R35 R46 F47 Q48 R79 V80 T81 P84233 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 4r8p G 3.28 BS02 NUC J 1 A12 A14 K15 R17 R20 G28 R29 R32 R42 A1 A3 K4 R6 R9 G17 R18 R21 R31 Q6AZJ8 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 4r8p H 3.28 BS02 NUC J 1 T32 Y42 G53 I54 S56 R86 S87 T88 T2 Y12 G23 I24 S26 R56 S57 T58 P02281 KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 4r8p L 3.28 BS01 NUC J 1 H232 H255 K266 H139 H162 K173 6.3.2.-,6.3.2.19 P61077 KTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSGSGSRSALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM 4r8p L 3.28 BS02 ZN L 1 C51 C54 C72 C75 C37 C40 C58 C61 6.3.2.-,6.3.2.19 P61077 KTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSGSGSRSALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM 4r8p L 3.28 BS03 ZN L 2 C67 H69 C87 T89 C90 C53 H55 C73 T75 C76 6.3.2.-,6.3.2.19 P61077 KTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSGSGSRSALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM 4r8p N 3.28 BS01 NUC J 1 S280 R325 K328 S186 R231 K234 6.3.2.-,6.3.2.19 P61077 TWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSGSGSRSALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM 4r8p N 3.28 BS02 ZN N 1 C51 C54 C72 C75 R121 C36 C39 C57 C60 R106 6.3.2.-,6.3.2.19 P61077 TWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSGSGSRSALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM 4r8y A 1.90 BS01 3KO A 1 S71 G74 L91 D93 G95 S96 V130 Y132 F169 I171 W176 R189 D289 G291 T292 T293 S14 G17 L34 D36 G38 S39 V73 Y75 F112 I114 W119 R132 D232 G234 T235 T236 3.4.23.46 GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI 4r91 A 1.58 BS01 3KT A 1 G74 D93 G95 S96 V130 Y132 F169 W176 R189 D289 G291 T292 T293 G17 D36 G38 S39 V73 Y75 F112 W119 R132 D232 G234 T235 T236 3.4.23.46 P56817 GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI 4r91 B 1.58 BS01 3KT B 1 G72 Q73 G74 D93 G95 S96 V130 Y132 F169 W176 R189 Y259 D289 G291 T292 T293 G15 Q16 G17 D36 G38 S39 V73 Y75 F112 W119 R132 Y202 D232 G234 T235 T236 3.4.23.46 P56817 GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4r92 A 1.71 BS01 3KU A 1 D93 G95 S96 V130 Y132 K168 F169 F170 I171 W176 R189 D289 G291 T292 D37 G39 S40 V74 Y76 K112 F113 F114 I115 W120 R133 D233 G235 T236 3.4.23.46 P56817 RGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI 4r95 A 1.99 BS01 3KW A 1 D93 G95 S96 V130 Y132 Q134 K168 F169 F170 I171 R189 D289 G291 T292 D36 G38 S39 V73 Y75 Q77 K111 F112 F113 I114 R132 D232 G234 T235 3.4.23.46 P56817 GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI 4r95 B 1.99 BS01 3KW B 1 L91 D93 G95 S96 V130 Y132 K168 F169 I171 R189 D289 G291 T292 L34 D36 G38 S39 V73 Y75 K111 F112 I114 R132 D232 G234 T235 3.4.23.46 P56817 GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4r9j B 2.10 BS03 3LJ B 2 R183 S184 G199 A200 R112 S113 G128 A129 Q15485 PCLTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA 4r9m A 2.90 BS01 MG A 1 E35 E76 E32 E73 2.3.1.57 MPSAHSVKLRPLEREDLRYVHQLDSVMRYWFEEPYEAFVELSDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQIIISPEYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFSVEGELMHEFFINGQYRNAIRMCIFQHQYLAE 4rb4 K 3.88 BS02 AQH K 1 T107 L108 G109 A110 F187 Q224 T226 K230 I255 D256 R257 L281 L283 R286 P300 S301 G302 W305 E326 T99 L100 G101 A102 F179 Q216 T218 K222 I247 D248 R249 L273 L275 R278 P292 S293 G294 W297 E318 2.4.-.- H5MH13 25310236 FITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQGVEAT 4rb4 L 3.88 BS02 AQH L 1 G106 T107 L108 G109 F187 Q224 S225 T226 I255 D256 R257 R286 P300 S301 G302 G87 T88 L89 G90 F167 Q204 S205 T206 I235 D236 R237 R265 P279 S280 G281 2.4.-.- H5MH13 25310236 FITPPDTPTQAGPENIFYDFNDGAWHVRLLDADSENILFCCDGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQGV 4rb4 C 3.88 BS02 AQH C 1 T107 L108 G109 A110 F187 Q224 S225 T226 K230 R257 L283 R286 P300 S301 G302 W305 F320 E326 T98 L99 G100 A101 F178 Q215 S216 T217 K221 R248 L274 R277 P291 S292 G293 W296 F311 E317 2.4.-.- H5MH13 25310236 ITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQGVEAT 4rb4 D 3.88 BS02 AQH D 1 T107 L108 G109 F187 Q224 S225 T226 K230 I255 D256 R257 L281 L283 R286 P300 S301 G302 L303 T98 L99 G100 F177 Q214 S215 T216 K220 I245 D246 R247 L271 L273 R276 P290 S291 G292 L293 2.4.-.- H5MH13 25310236 ITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLT 4rb4 E 3.88 BS02 AQH E 1 T107 L108 G109 A110 F187 Q224 T226 K230 I255 R257 L281 L283 R286 P300 S301 G302 L303 F320 E326 T98 L99 G100 A101 F178 Q215 T217 K221 I246 R248 L272 L274 R277 P291 S292 G293 L294 F311 E317 2.4.-.- H5MH13 25310236 ITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQGVEATL 4rb4 H 3.88 BS02 AQH H 1 L108 G109 A110 F187 Q224 S225 T226 K230 R257 L281 L283 R286 P300 S301 G302 L303 F320 W343 L99 G100 A101 F178 Q215 S216 T217 K221 R248 L272 L274 R277 P291 S292 G293 L294 F311 W334 2.4.-.- H5MH13 25310236 ITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQG 4rb4 B 3.88 BS02 AQH B 1 T107 G109 A110 F187 Q224 T226 K230 I255 R257 L281 L283 R286 P300 S301 G302 W305 F320 S321 E326 T99 G101 A102 F179 Q216 T218 K222 I247 R249 L273 L275 R278 P292 S293 G294 W297 F312 S313 E318 2.4.-.- H5MH13 25310236 FITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLT 4rb4 G 3.88 BS02 AQH G 1 T107 L108 A110 F187 S225 T226 K230 D256 R257 L281 R286 P300 S301 G302 L303 E326 W343 T97 L98 A100 F177 S215 T216 K220 D246 R247 L271 R276 P290 S291 G292 L293 E316 W333 2.4.-.- H5MH13 25310236 TPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQGVEATL 4rb4 I 3.88 BS02 AQH I 1 T107 L108 G109 A110 F187 Q224 S225 T226 K230 I255 D256 R257 R286 P300 S301 G302 L303 F320 T98 L99 G100 A101 F178 Q215 S216 T217 K221 I246 D247 R248 R277 P291 S292 G293 L294 F311 2.4.-.- 25310236 ITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQGVEAT 4rb4 J 3.88 BS02 AQH J 1 T107 L108 G109 A110 F187 T226 K230 R257 L281 L283 R286 P300 S301 G302 L303 W305 E326 W343 T99 L100 G101 A102 F179 T218 K222 R249 L273 L275 R278 P292 S293 G294 L295 W297 E318 W335 2.4.-.- H5MH13 25310236 FITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQ 4rb4 A 3.88 BS02 AQH A 1 T107 G109 A110 F187 S225 T226 K230 R257 L281 L283 R286 P300 S301 G302 E326 T97 G98 A99 F176 S214 T215 K219 R246 L270 L272 R275 P289 S290 G291 E315 2.4.-.- H5MH13 25310236 ITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGETPLLDETLKLKDRPVLISFPTGTGALLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLT 4rk3 A 1.80 BS01 GOL A 1 N71 R196 N248 Y276 D277 Q294 N13 R132 N184 Y212 D213 Q230 Q036L9 TGNIGVLVSRVTNPFFAGLFDAIERELHAHGYQVMITQTYDDPEAEERFLKQLKSRELDGVILASVEAPDRVMAVAKAFPGRVVVVNADVQIPGATSLVLPHYQATRDALDYLFNQGHRRFAYVSGGTISSRTQAFLDFMQAHQLLVAQDLLFGQIHTAKEGQAVGKQLASLAPNVRPDAVFTNSDEVAVGVIDSLLAADVKVPDDIAVMGYDDQPFAPFAKIPLTTVHQPVASMAAAATHELLKGLGRQVAQDTQPTLHLSLKIRQSA 4rk5 A 1.35 BS01 SUC A 1 S67 R68 N71 F74 N145 G184 H192 R196 H221 N248 D277 Q294 S9 R10 N13 F16 N87 G126 H134 R138 H163 N190 D219 Q236 Q036L9 TGNIGVLVSRVTNPFFAGLFDAIERELHAHGYQVMITQTYDDPEAEERFLKQLKSRELDGVILASVEAPDRVMAVAKAFPGRVVVVNADVQIPGATSLVLPHYQATRDALDYLFNQGHRRFAYVSGGTISGAHHGQSRTQAFLDFMQAHQLLVAQDLLFGQIHTAKEGQAVGKQLASLAPNVRPDAVFTNSDEVAVGVIDSLLAADVKVPDDIAVMGYDDQPFAPFAKIPLTTVHQPVASMAAAATHELLKGLGRQVAQDTQPTLHLSLKIRQSA 4rk9 A 2.15 BS01 GLC A 1 T39 M40 T41 E45 V270 H308 T8 M9 T10 E14 V239 H277 Q65LL6 VTLTMFSTMTNDSEKNTLRSIADDFEKENEGIKIDISFPGPDYENMLRVKMAANDMPDLFDTHGWAKIRYGEYTADLKDMDWVKHLDPNLDPILKDEKGKVYAYPFNQAKDGIVYNAGLLKKYGLKPPQTLDELMHALETIKEKSNGSVIPFWFAGSDKGALAQFYDQLATPLLITDDRRNEKKALENGTFDWSDYTLLAETFKEMQEKQLINKDILTAKPSQLVELMAQEKIGFTLSVTSIGPDTREVNPDIQLGVMPTPAVYEGDKPSWIGGERHTVAVWKDSEHLEEAKRFIEFAAQPKYVKKIAEATSFPQALTNTEAENYYSKFYDQYEEIKIEPYFDRVYLPSGMWDVMGTTGQELLAGTLTPKQVSEKMKQEYSRLQ 4rk9 A 2.15 BS02 GLA A 1 T39 G71 P72 E75 W383 T8 G40 P41 E44 W352 Q65LL6 VTLTMFSTMTNDSEKNTLRSIADDFEKENEGIKIDISFPGPDYENMLRVKMAANDMPDLFDTHGWAKIRYGEYTADLKDMDWVKHLDPNLDPILKDEKGKVYAYPFNQAKDGIVYNAGLLKKYGLKPPQTLDELMHALETIKEKSNGSVIPFWFAGSDKGALAQFYDQLATPLLITDDRRNEKKALENGTFDWSDYTLLAETFKEMQEKQLINKDILTAKPSQLVELMAQEKIGFTLSVTSIGPDTREVNPDIQLGVMPTPAVYEGDKPSWIGGERHTVAVWKDSEHLEEAKRFIEFAAQPKYVKKIAEATSFPQALTNTEAENYYSKFYDQYEEIKIEPYFDRVYLPSGMWDVMGTTGQELLAGTLTPKQVSEKMKQEYSRLQ 4rk9 A 2.15 BS03 GLA A 2 E75 H94 W96 Q195 R307 Y372 D374 R375 W383 E44 H63 W65 Q164 R276 Y341 D343 R344 W352 Q65LL6 VTLTMFSTMTNDSEKNTLRSIADDFEKENEGIKIDISFPGPDYENMLRVKMAANDMPDLFDTHGWAKIRYGEYTADLKDMDWVKHLDPNLDPILKDEKGKVYAYPFNQAKDGIVYNAGLLKKYGLKPPQTLDELMHALETIKEKSNGSVIPFWFAGSDKGALAQFYDQLATPLLITDDRRNEKKALENGTFDWSDYTLLAETFKEMQEKQLINKDILTAKPSQLVELMAQEKIGFTLSVTSIGPDTREVNPDIQLGVMPTPAVYEGDKPSWIGGERHTVAVWKDSEHLEEAKRFIEFAAQPKYVKKIAEATSFPQALTNTEAENYYSKFYDQYEEIKIEPYFDRVYLPSGMWDVMGTTGQELLAGTLTPKQVSEKMKQEYSRLQ 4rk9 A 2.15 BS04 FRU A 1 T41 D189 G191 Q195 V270 T271 T10 D158 G160 Q164 V239 T240 Q65LL6 VTLTMFSTMTNDSEKNTLRSIADDFEKENEGIKIDISFPGPDYENMLRVKMAANDMPDLFDTHGWAKIRYGEYTADLKDMDWVKHLDPNLDPILKDEKGKVYAYPFNQAKDGIVYNAGLLKKYGLKPPQTLDELMHALETIKEKSNGSVIPFWFAGSDKGALAQFYDQLATPLLITDDRRNEKKALENGTFDWSDYTLLAETFKEMQEKQLINKDILTAKPSQLVELMAQEKIGFTLSVTSIGPDTREVNPDIQLGVMPTPAVYEGDKPSWIGGERHTVAVWKDSEHLEEAKRFIEFAAQPKYVKKIAEATSFPQALTNTEAENYYSKFYDQYEEIKIEPYFDRVYLPSGMWDVMGTTGQELLAGTLTPKQVSEKMKQEYSRLQ 4rk9 B 2.15 BS01 GLC B 1 T39 M40 T41 N42 E45 V270 T271 H308 T8 M9 T10 N11 E14 V239 T240 H277 Q65LL6 VTLTMFSTMTNDSEKNTLRSIADDFEKENEGIKIDISFPGPDYENMLRVKMAANDMPDLFDTHGWAKIRYGEYTADLKDMDWVKHLDPNLDPILKDEKGKVYAYPFNQAKDGIVYNAGLLKKYGLKPPQTLDELMHALETIKEKSNGSVIPFWFAGSDKGALAQFYDQLATPLLITDDRRNEKKALENGTFDWSDYTLLAETFKEMQEKQLINKDILTAKPSQLVELMAQEKIGFTLSVTSIGPDTREVNPDIQLGVMPTPAVYEGDKPSWIGGERHTVAVWKDSEHLEEAKRFIEFAAQPKYVKKIAEATSFPQALTNTEAENYYSKFYDQYEEIKIEPYFDRVYLPSGMWDVMGTTGQELLAGTLTPKQVSEKMKQEYSRLQ 4rk9 B 2.15 BS02 GLA B 1 P72 E75 H94 W383 P41 E44 H63 W352 Q65LL6 VTLTMFSTMTNDSEKNTLRSIADDFEKENEGIKIDISFPGPDYENMLRVKMAANDMPDLFDTHGWAKIRYGEYTADLKDMDWVKHLDPNLDPILKDEKGKVYAYPFNQAKDGIVYNAGLLKKYGLKPPQTLDELMHALETIKEKSNGSVIPFWFAGSDKGALAQFYDQLATPLLITDDRRNEKKALENGTFDWSDYTLLAETFKEMQEKQLINKDILTAKPSQLVELMAQEKIGFTLSVTSIGPDTREVNPDIQLGVMPTPAVYEGDKPSWIGGERHTVAVWKDSEHLEEAKRFIEFAAQPKYVKKIAEATSFPQALTNTEAENYYSKFYDQYEEIKIEPYFDRVYLPSGMWDVMGTTGQELLAGTLTPKQVSEKMKQEYSRLQ 4rk9 B 2.15 BS03 GLA B 2 E75 H94 W96 Q195 D198 R307 Y372 D374 R375 W383 E44 H63 W65 Q164 D167 R276 Y341 D343 R344 W352 Q65LL6 VTLTMFSTMTNDSEKNTLRSIADDFEKENEGIKIDISFPGPDYENMLRVKMAANDMPDLFDTHGWAKIRYGEYTADLKDMDWVKHLDPNLDPILKDEKGKVYAYPFNQAKDGIVYNAGLLKKYGLKPPQTLDELMHALETIKEKSNGSVIPFWFAGSDKGALAQFYDQLATPLLITDDRRNEKKALENGTFDWSDYTLLAETFKEMQEKQLINKDILTAKPSQLVELMAQEKIGFTLSVTSIGPDTREVNPDIQLGVMPTPAVYEGDKPSWIGGERHTVAVWKDSEHLEEAKRFIEFAAQPKYVKKIAEATSFPQALTNTEAENYYSKFYDQYEEIKIEPYFDRVYLPSGMWDVMGTTGQELLAGTLTPKQVSEKMKQEYSRLQ 4rl6 A 2.79 BS01 NDP A 1 C9 G10 G11 V12 S34 R35 T36 K39 L60 D61 A62 D63 A84 L85 P86 Q88 T106 A107 G160 F161 D162 P163 T366 C8 G9 G10 V11 S33 R34 T35 K38 L59 D60 A61 D62 A83 L84 P85 Q87 T105 A106 G159 F160 D161 P162 T361 1.5.1.7 Q04L03 SRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLKAKLEGKTSTKIETAALDADKVEEVIALIGSYKPEAVLNVALPYQDLTIMDACLATGVHYIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSGFDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYWEDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSYLTHMKCLENVGLLRTDTINFIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEELDPDPFMEALNEYGLPWVVVENPQMVD 4rl6 B 2.79 BS01 NDP B 1 C9 G10 G11 V12 R35 T36 K39 L60 A62 D63 A84 L85 P86 Q88 T106 A107 D162 T366 C8 G9 G10 V11 R34 T35 K38 L59 A61 D62 A83 L84 P85 Q87 T105 A106 D161 T343 1.5.1.7 Q04L03 SRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLKAKLEGKTSTKIETAALDADKVEEVIALIGSYKPEAVLNVALPYQDLTIMDACLATGVHYIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSGFDPGVTSVFSAYALKHYFDEIHYIDILDCNFNPEINLREVSAPGSYWEDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSYLTHMKCLENVGLLRTDGQEIVPIQFLKALLGPRTVGKTNIGCIFTGVKDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEELDPDPFMEALNEYGLPWVVVENPQMVD 4rn6 A 3.00 BS01 15U A 1 H57 Y60A W60D E97A L99 L144 W148 W215 G216 E217 G219 H74 Y78 W81 E125 L127 L175 W179 W252 G253 E254 G255 3.4.21.5 P00734 23467412 EADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTAPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 4rn6 B 3.00 BS01 15U B 1 H57 Y60A W60D L99 L144 W148 V213 W215 G216 E217 G219 G226 H74 Y78 W81 L127 L175 W179 V250 W252 G253 E254 G255 G263 3.4.21.5 P00734 23467412 EADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTAPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 4rn7 A 1.72 BS01 ZN A 1 H125 E141 H195 H12 E28 H82 3.5.1.28 Q183J9 SNAYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQKDIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATDGSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIINEKYQDQLAEGIVQGVLSYLDSKG 4tk0 A 1.65 BS02 32Z A 1 H1031 G1032 G1053 Y1060 F1061 A1062 K1067 S1068 Y1071 I1075 E1138 H70 G71 G92 Y99 F100 A101 K106 S107 Y110 I114 E177 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tkf A 2.60 BS02 33C A 1 H1031 G1032 S1033 F1035 A1038 I1039 G1043 F1044 D1045 H1048 A1049 Y1050 G1058 I1059 Y1060 Y1071 H70 G71 S72 F74 A77 I78 G82 F83 D84 H87 A88 Y89 G97 I98 Y99 Y110 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tkf A 2.60 BS03 3AB A 1 H1031 G1032 M1054 Y1060 F1061 A1062 K1067 S1068 Y1071 E1138 H70 G71 M93 Y99 F100 A101 K106 S107 Y110 E177 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tkf B 2.60 BS02 33C B 1 H1031 S1033 F1035 A1038 I1039 G1043 F1044 D1045 H1048 A1049 I1059 Y1060 Y1071 I1075 H75 S77 F79 A82 I83 G87 F88 D89 H92 A93 I103 Y104 Y115 I119 2.4.2.30 Q9H2K2 FQGSPDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tkf C 2.60 BS02 33C C 1 H1031 F1035 A1038 G1043 F1044 D1045 H1048 I1059 Y1060 Y1071 I1075 H79 F83 A86 G91 F92 D93 H96 I107 Y108 Y119 I123 2.4.2.30 Q9H2K2 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tmp A 2.30 BS01 III B 1 F28 H30 H56 S58 F59 S76 G77 Y78 A79 G80 F81 I82 D103 F105 L106 H107 L108 H111 F28 H30 H56 S58 F59 S76 G77 Y78 A79 G80 F81 I82 D103 F105 L106 H107 L108 H111 P42568 MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKA 4tvv A 1.40 BS01 PO4 A 1 H203 K235 G236 Y270 Y286 R289 H174 K206 G207 Y241 Y257 R260 Q5ZRR1 25339170 SIVCDSTIENPCIVQDSKTQFSPVIRYREVASIADVYGGNITGINKFHLSGSEQPSEKGWEAIAESISRKMKKVIVLDLRQESHGYLNGRAITLVSAYNWINLGKSNSQSTLDQENWLAGLRSRKIVNGVLTVPQYVAKQYSQGKSMVVSTVKNEEYYVYKKGFDYYRIFISDHRAPLDSEVDALVALIKNNPEDTWYHVHCRGGKGRTTTVFAMFDMLKNADKVSFEEIIARQASIPPFYNLMVTNREIPELTPYYEQRLQFLIHFYEFARQSLMGYSGTWSEW 4tvv A 1.40 BS02 PO4 A 2 D202 C231 R232 G233 G234 K235 R237 D173 C202 R203 G204 G205 K206 R208 Q5ZRR1 25339170 SIVCDSTIENPCIVQDSKTQFSPVIRYREVASIADVYGGNITGINKFHLSGSEQPSEKGWEAIAESISRKMKKVIVLDLRQESHGYLNGRAITLVSAYNWINLGKSNSQSTLDQENWLAGLRSRKIVNGVLTVPQYVAKQYSQGKSMVVSTVKNEEYYVYKKGFDYYRIFISDHRAPLDSEVDALVALIKNNPEDTWYHVHCRGGKGRTTTVFAMFDMLKNADKVSFEEIIARQASIPPFYNLMVTNREIPELTPYYEQRLQFLIHFYEFARQSLMGYSGTWSEW 4tvv B 1.40 BS01 PO4 B 1 H203 K235 G236 Y270 R277 Y286 R289 H177 K209 G210 Y244 R251 Y260 R263 Q5ZRR1 25339170 IVCDSTIENPCIVQDSKTQFSPVIRYREVASIADVYGGNITGINKFHLSGSEQPSEKGWEAIAESISRKMGAETKKVIVLDLRQESHGYLNGRAITLVSAYNWINLGKSNSQSTLDQENWLAGLRSRKIVNGVLTVPQYVAKQYSQGKSMVVSTVKNEEYYVYKKGFDYYRIFISDHRAPLDSEVDALVALIKNNPEDTWYHVHCRGGKGRTTTVFAMFDMLKNADKVSFEEIIARQASIPPFYNLMVTNREIPELTPYYEQRLQFLIHFYEFARQSLMGYSGTWSEW 4tvv B 1.40 BS02 PO4 B 2 D202 C231 R232 G233 G234 K235 G236 R237 D176 C205 R206 G207 G208 K209 G210 R211 Q5ZRR1 25339170 IVCDSTIENPCIVQDSKTQFSPVIRYREVASIADVYGGNITGINKFHLSGSEQPSEKGWEAIAESISRKMGAETKKVIVLDLRQESHGYLNGRAITLVSAYNWINLGKSNSQSTLDQENWLAGLRSRKIVNGVLTVPQYVAKQYSQGKSMVVSTVKNEEYYVYKKGFDYYRIFISDHRAPLDSEVDALVALIKNNPEDTWYHVHCRGGKGRTTTVFAMFDMLKNADKVSFEEIIARQASIPPFYNLMVTNREIPELTPYYEQRLQFLIHFYEFARQSLMGYSGTWSEW 4u8w A 1.30 BS01 G10 A 1 L23 D25 G27 A28 D30 V32 G48 G49 I50 P81 V82 I84 L23 D25 G27 A28 D30 V32 G48 G49 I50 P81 V82 I84 3.4.23.16 P03366 25336073 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF 4ubs A 2.20 BS01 HEM A 1 L92 L93 H100 R104 L237 L238 A241 G242 T245 M249 L282 A288 L291 R293 A343 F344 G345 H349 C351 L352 G353 A357 M361 L83 L84 H91 R95 L228 L229 A232 G233 T236 M240 L273 A279 L282 R284 A334 F335 G336 H340 C342 L343 G344 A348 M352 1.14.15.11 Q825I8 25341403 APVAFPQDRTCPYDPPTAYDPLREGRPLSRVSLYDGRSVWVVTGHAAARALLSDQRLSSDRTLPRFPATTERFEAVRTRRVALLGVDDPEHRTQRRMLVPSFTLKRAAALRPRIQETVDGLLDAMEAQGPPAELVSAFALPLPSMVICALLGVPYADHDFFESQSRRLLRGPGIAEVQDARAQLDDYLYALIDRKRKEPGDGLLDDLIQEQLNRGTVDRAELVSLATLLLIAGHETTANMISLGTFTLLRHPEQLAELRAEPGLMPAAVEELLRFLSIADGLLRVATEDIEVAGTTIRADEGVVFATSVINRDAAGFAEPDALDWHRSARHHVAFGFGIHQCLGQNLARAEMEIALGTLFERLPGLRLAAPADEIPFKPGDTIQGMLELPVTW 4ubs A 2.20 BS02 DIF A 1 R70 V85 L93 L177 S233 T236 L237 I240 R61 V76 L84 L168 S224 T227 L228 I231 1.14.15.11 Q825I8 25341403 APVAFPQDRTCPYDPPTAYDPLREGRPLSRVSLYDGRSVWVVTGHAAARALLSDQRLSSDRTLPRFPATTERFEAVRTRRVALLGVDDPEHRTQRRMLVPSFTLKRAAALRPRIQETVDGLLDAMEAQGPPAELVSAFALPLPSMVICALLGVPYADHDFFESQSRRLLRGPGIAEVQDARAQLDDYLYALIDRKRKEPGDGLLDDLIQEQLNRGTVDRAELVSLATLLLIAGHETTANMISLGTFTLLRHPEQLAELRAEPGLMPAAVEELLRFLSIADGLLRVATEDIEVAGTTIRADEGVVFATSVINRDAAGFAEPDALDWHRSARHHVAFGFGIHQCLGQNLARAEMEIALGTLFERLPGLRLAAPADEIPFKPGDTIQGMLELPVTW 4ubs A 2.20 BS03 DIF A 2 T245 D289 G290 L291 L292 T236 D280 G281 L282 L283 1.14.15.11 Q825I8 25341403 APVAFPQDRTCPYDPPTAYDPLREGRPLSRVSLYDGRSVWVVTGHAAARALLSDQRLSSDRTLPRFPATTERFEAVRTRRVALLGVDDPEHRTQRRMLVPSFTLKRAAALRPRIQETVDGLLDAMEAQGPPAELVSAFALPLPSMVICALLGVPYADHDFFESQSRRLLRGPGIAEVQDARAQLDDYLYALIDRKRKEPGDGLLDDLIQEQLNRGTVDRAELVSLATLLLIAGHETTANMISLGTFTLLRHPEQLAELRAEPGLMPAAVEELLRFLSIADGLLRVATEDIEVAGTTIRADEGVVFATSVINRDAAGFAEPDALDWHRSARHHVAFGFGIHQCLGQNLARAEMEIALGTLFERLPGLRLAAPADEIPFKPGDTIQGMLELPVTW 4umo A 3.00 BS01 K A 1 W392 F398 R507 W37 F43 R47 P51787 QQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIEFSQLREHHRATIKVIRRMQYFVAKKKFQQARKP 4umo A 3.00 BS02 K A 2 Y395 E397 F398 Y40 E42 F43 P51787 QQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIEFSQLREHHRATIKVIRRMQYFVAKKKFQQARKP 4umo A 3.00 BS03 K B 1 R507 H510 R511 R47 H50 R51 P51787 QQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIEFSQLREHHRATIKVIRRMQYFVAKKKFQQARKP 4up0 A 1.28 BS01 III F 1 D339 Q341 A343 I344 L345 E347 W353 Y366 L369 T370 E372 A375 D14 Q16 A18 I19 L20 E22 W28 Y41 L44 T45 E47 A50 Q86UU0 25323450 GVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCVYVFTTHLANTAAEAVLQGRADSILAYH 4up0 A 1.28 BS02 ZN A 1 C330 C333 H355 C358 C5 C8 H30 C33 Q86UU0 25323450 GVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCVYVFTTHLANTAAEAVLQGRADSILAYH 4up0 A 1.28 BS03 ZN A 2 C346 C350 C379 C382 C21 C25 C54 C57 Q86UU0 25323450 GVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCVYVFTTHLANTAAEAVLQGRADSILAYH 4up5 A 1.65 BS03 94W A 1 A332 F354 C358 T359 W377 C379 D380 T1240 A7 F29 C33 T34 W52 C54 D55 T63 Q86UU0 25323450 GVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCVYVFTTHLANTAAEAVLQGRADSILAYH 4uyj A 3.35 BS01 NUC R 1 R26 K30 R32 D45 L46 C48 K52 R25 K29 R31 D44 L45 C47 K51 P49458 25336584 PQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGNLCVKVTDDLVCLVYKTDQAQDVKKIEKFHSQLMRLMVA 4uyj B 3.35 BS01 NUC R 1 M1 G24 S25 Y27 K31 Y33 R36 T37 K38 R59 K64 K66 M1 G24 S25 Y27 K31 Y33 R36 T37 K38 R48 K53 K55 P37108 25336584 MVLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDG 4uyj C 3.35 BS01 NUC S 1 P2 R26 K30 R32 K41 D45 L46 C48 K52 P1 R25 K29 R31 K40 D44 L45 C47 K51 P49458 25336584 PQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGNLCVKVTDDLVCLVYKTDQAQDVKKIEKFHSQLMRLMVA 4uyj D 3.35 BS01 NUC S 1 M1 G24 S25 Y27 K31 Y33 R36 T37 K38 P39 L57 R59 K66 M1 G24 S25 Y27 K31 Y33 R36 T37 K38 P39 L46 R48 K55 P37108 25336584 MVLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGL 4uyk A 3.22 BS01 NUC R 1 R26 K30 R32 K41 D45 L46 C48 K52 R25 K29 R31 K40 D44 L45 C47 K51 P49458 25336584 PQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGNLCVKVTDDLVCLVYKTDQAQDVKKIEKFHSQLMRLMVAKEARNVTM 4v2v A 2.00 BS01 III C 1 N86 D135 N137 I168 E169 G170 Y175 Y177 E190 K241 S288 T289 N290 D311 V313 N84 D133 N135 I166 E167 G168 Y173 Y175 E188 K239 S286 T287 N288 D309 V311 1.14.11.- O75164 SESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLK 4v2v B 2.00 BS01 III D 1 N86 D135 I168 E169 G170 Y175 Y177 E190 K241 S288 T289 N290 V313 N80 D129 I162 E163 G164 Y169 Y171 E184 K235 S282 T283 N284 V307 1.14.11.- O75164 TLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFL 4w1o A 2.20 BS01 3GJ A 1 Y159 H160 T271 M273 D318 L319 N321 Y329 W332 T333 I336 F340 M357 S368 Q369 F372 I376 Y70 H71 T182 M184 D229 L230 N232 Y240 W243 T244 I247 F251 M268 S279 Q280 F283 I287 3.1.4.53 Q08499 24984230 DVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 4w1o B 2.20 BS01 3GJ B 1 Y159 H160 T271 M273 D318 L319 N321 Y329 T333 I336 F340 M357 S368 Q369 F372 Y77 H78 T189 M191 D232 L233 N235 Y243 T247 I250 F254 M271 S282 Q283 F286 3.1.4.53 Q08499 24984230 GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP 4wap O 3.09 BS01 NUC B 1 K3 R15 R25 H29 R30 T31 P32 R33 H34 Y36 Q38 I40 N43 G44 S45 E46 V47 V54 E55 K63 Y64 G66 N67 K68 Q98 H100 G101 R102 K2 R14 R24 H28 R29 T30 P31 R32 H33 Y35 Q37 I39 N42 G43 S44 E45 V46 V53 E54 K62 Y63 G65 N66 K67 Q97 H99 G100 R101 P0C018 DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF 4wbo A 2.81 BS01 ANW A 1 L193 A214 M264 T265 M267 N268 L321 V476 A478 L166 A187 M237 T238 M240 N241 L294 V449 A451 2.7.11.14 P28327 25340299 PASRDRKYLARLKLPPLSKCEALRESLDLGFEGMCLEQPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAGAGDGLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENVLLDDDGNVRISDLGLAVELKAGQTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKNIKGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP 4wbo B 2.81 BS01 ANW B 1 L193 A214 M264 T265 M267 N268 L321 A478 L164 A185 M235 T236 M238 N239 L292 A449 2.7.11.14 P28327 25340299 SRDRKYLARLKLPPLSKCEALRESLDLGFEGMCLEQPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAGAGDGLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENVLLDDDGNVRISDLGLAVELKAGQTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKNIQGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP 4wbo C 2.81 BS01 ANW C 1 L193 A214 M264 T265 M267 N268 L321 L163 A184 M234 T235 M237 N238 L291 2.7.11.14 P28327 25340299 RDRKYLARLKLPPLSKCEALRESLDLGFEGMCLEQPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAGAGDGLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENVLLDDDGNVRISDLGLAVELKAGQTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVW 4wbo D 2.81 BS01 ANW D 1 L193 A214 M264 T265 M267 N268 G270 L321 Y477 A478 L159 A180 M230 T231 M233 N234 G236 L287 Y443 A444 2.7.11.14 P28327 25340299 SRDRKYLARLKLPPLSKCEALRESLDLGFEGMCLEQPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARALFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENVLLDDDGNVRISDLGLAVELKAGQTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKNIQDVKGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVW 4wg2 A 2.66 BS01 HEM A 1 K69 L86 V87 W96 I153 F261 A264 G265 A268 T269 T327 A328 F331 P392 F393 G394 R398 S400 I401 G402 A406 K66 L83 V84 W93 I150 F258 A261 G262 A265 T266 T324 A325 F328 P389 F390 G391 R395 S397 I398 G399 A403 1.14.14.1,1.6.2.4 P14779 25325618 EMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFARDFAGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLFAGHEATSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLSLKPKGFVVKAKSKKIPLGGIPSPSTH 4wh5 A 1.82 BS01 MG A 1 D46 D48 D43 D45 P06107 NNVTEKELFYILDLFEHMKVTYWLDGGWGVDVLTGKQQREHRDIDIDFDAQHTQKVIQKLEDIGYKIEVHWMPSRMELKHEEYGYLDIHPINLNDDGSITQANPEGGNYVFQNDWFSETNYKDRKIPCISKEAQLLFHSGYDLTETDHFDIKNLKSIT 4wh5 A 1.82 BS02 MG A 2 G29 G30 D46 D48 G26 G27 D43 D45 P06107 NNVTEKELFYILDLFEHMKVTYWLDGGWGVDVLTGKQQREHRDIDIDFDAQHTQKVIQKLEDIGYKIEVHWMPSRMELKHEEYGYLDIHPINLNDDGSITQANPEGGNYVFQNDWFSETNYKDRKIPCISKEAQLLFHSGYDLTETDHFDIKNLKSIT 4wh5 A 1.82 BS03 3QB A 1 D28 G29 G30 D50 H92 W118 F119 I132 A136 Q137 F140 H141 D25 G26 G27 D47 H89 W115 F116 I129 A133 Q134 F137 H138 P06107 NNVTEKELFYILDLFEHMKVTYWLDGGWGVDVLTGKQQREHRDIDIDFDAQHTQKVIQKLEDIGYKIEVHWMPSRMELKHEEYGYLDIHPINLNDDGSITQANPEGGNYVFQNDWFSETNYKDRKIPCISKEAQLLFHSGYDLTETDHFDIKNLKSIT 4wh5 B 1.82 BS01 MG B 1 D46 D48 D90 D43 D45 D87 P06107 NNVTEKELFYILDLFEHMKVTYWLDGGWGVDVLTGKQQREHRDIDIDFDAQHTQKVIQKLEDIGYKIEVHWMPSRMELKHEEYGYLDIHPINLNDDGSITQANPEGGNYVFQNDWFSETNYKDRKIPCISKEAQLLFHSGYDLTETDHFDIKNLKSIT 4wh5 B 1.82 BS03 3QB B 1 D28 D48 D50 R78 D90 H92 F119 F140 D25 D45 D47 R75 D87 H89 F116 F137 P06107 NNVTEKELFYILDLFEHMKVTYWLDGGWGVDVLTGKQQREHRDIDIDFDAQHTQKVIQKLEDIGYKIEVHWMPSRMELKHEEYGYLDIHPINLNDDGSITQANPEGGNYVFQNDWFSETNYKDRKIPCISKEAQLLFHSGYDLTETDHFDIKNLKSIT 4wkq A 1.85 BS01 IRE A 1 L718 A743 K745 E762 M766 L788 T790 Q791 M793 P794 G796 C797 D800 L844 T854 L25 A47 K49 E61 M65 L87 T89 Q90 M92 P93 G95 C96 D99 L143 T153 2.7.10.1 P00533 AMGEAPNQALLRILKETEFKKIKVLGSGTVYKGLWIPEGEKVKIPVAIKESPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDMDDVVDADEYLIPQ 4wnr A 2.90 BS01 GDP A 1 G330 E331 A332 G333 K334 T335 S336 F346 G348 E350 H351 N430 K431 D433 E434 S459 C460 K461 G24 E25 A26 G27 K28 T29 S30 F40 G42 E44 H45 N124 K125 D127 E128 S153 C154 K155 Q46A62 25317655 NYFKSLEGEKKPLNEVKVLLVGDGEAGKTSLLKRLLGEGFDGNEHQTQGINIKKWGFKDKDKEIKVNFWDFGGQEIMHATHQFFLSKRSLYILVLDSRRDEKAEYWLKHIRSFGGDSPVLVALNKIDENPSFELNRKFLQEKYPSIKGFFRISCKEDRGIEGFSQKLKKELLKVEHMQIEWAKSWFEVKTKLEKMSCNFITYEEYRNICLEENVGDKSSQNTLVDFLNDLGVIVHFKDISLLDTHVLEPKWITEGVYKIINSEILAKKKGVLRFSMLDEILEQKKEGDYYYPPERYGYIINLMKKFELCYSIDEETVLLPDLL 4wrh A 1.60 BS01 NAP A 1 G22 T23 Y24 D50 Y55 H117 S166 N167 Q190 Y216 S217 A218 L219 G220 S221 Q222 L236 A253 L268 A269 K270 S271 Y272 R276 Q279 N280 G17 T18 Y19 D45 Y50 H112 S161 N162 Q185 Y211 S212 A213 L214 G215 S216 Q217 L231 A248 L263 A264 K265 S266 Y267 R271 Q274 N275 1.-.-.-,1.1.1.357,1.1.1.112,1.1.1.188,1.1.1.239,1.1.1.64 P42330 QCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSD 4wrh A 1.60 BS02 YY2 A 1 W86 S118 M120 L122 S129 V137 N167 Y216 F306 F311 P318 W81 S113 M115 L117 S124 V132 N162 Y211 F301 F306 P313 1.-.-.-,1.1.1.357,1.1.1.112,1.1.1.188,1.1.1.239,1.1.1.64 P42330 QCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSD 4wrh A 1.60 BS03 YY1 A 1 Y24 L54 Y55 H117 Y19 L49 Y50 H112 1.-.-.-,1.1.1.357,1.1.1.112,1.1.1.188,1.1.1.239,1.1.1.64 P42330 QCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSD 4wsq A 1.95 BS01 ZN A 1 H185 D186 H189 H157 D158 H161 2.7.11.1 Q2M2I8 GLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAK 4wsq A 1.95 BS02 ZN A 2 D127 H185 D99 H157 2.7.11.1 Q2M2I8 GLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAK 4wsq A 1.95 BS03 ZN A 3 D176 D194 D148 D166 2.7.11.1 Q2M2I8 GLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAK 4wsq A 1.95 BS04 KSA A 1 L52 A53 V60 A72 K74 M126 D127 F128 C129 G132 Q133 E180 N181 L183 C193 D194 L24 A25 V32 A44 K46 M98 D99 F100 C101 G104 Q105 E152 N153 L155 C165 D166 2.7.11.1 Q2M2I8 GLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAK