1vy0 B 3.68 BS01 NUC A 1 W24 P26 R96 L98 G99 G100 T103 N104 T107 R111 K133 H140 Y148 I172 E176 K179 W21 P23 R93 L95 G96 G97 T100 N101 T104 R108 K130 H137 Y145 I169 E173 K176 P80371 EITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 1vy0 C 3.68 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 R127 S154 G155 R156 E161 Q162 A163 R172 V173 P174 L175 H176 T177 L178 R179 F186 R190 T192 Y193 G194 V195 L196 K199 G1 N2 K3 I4 F9 K25 R126 S153 G154 R155 E160 Q161 A162 R171 V172 P173 L174 H175 T176 L177 R178 F185 R189 T191 Y192 G193 V194 L195 K198 P80372 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGE 1vy0 D 3.68 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 G23 E24 R25 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 S52 Y54 A55 L58 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 K85 K86 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 S137 R141 K151 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 G22 E23 R24 R34 R35 Y37 P39 G40 Q41 H42 Q44 R48 S51 Y53 A54 L57 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 K84 K85 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 S136 R140 K150 E155 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 1vy0 E 3.68 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 F45 K47 P49 K57 G85 A86 K92 A94 A95 T98 I101 A102 L119 T120 K121 E122 L123 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 F41 K43 P45 K53 G81 A82 K88 A90 A91 T94 I97 A98 L115 T116 K117 E118 L119 S121 R122 N123 N126 Y129 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 1vy0 F 3.68 BS01 NUC A 1 R2 Y4 K54 E69 V72 N73 R77 R80 R87 V90 V91 K92 R2 Y4 K54 E69 V72 N73 R77 R80 R87 V90 V91 K92 Q5SLP8 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 1vy0 G 3.68 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 R79 R94 S98 R102 R114 R115 A116 R119 W156 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 R78 R93 S97 R101 R113 R114 A115 R118 W155 P17291 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 1vy0 H 3.68 BS01 NUC A 1 M1 T3 D4 P5 A7 D8 T11 R12 R14 N15 R18 V19 K21 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 S113 T114 S115 V129 G130 E132 M1 T3 D4 P5 A7 D8 T11 R12 R14 N15 R18 V19 K21 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 S113 T114 S115 V129 G130 E132 Q5SHQ2 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 1vy0 I 3.68 BS01 NUC A 1 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 G39 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 R107 V108 E110 R111 K112 K113 Y114 G115 K116 H117 K118 R120 R121 A122 P123 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 G38 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 R106 V107 E109 R110 K111 K112 Y113 G114 K115 H116 K117 R119 R120 A121 P122 Q123 Y124 S125 K126 R127 P80374 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 1vy0 J 3.68 BS01 NUC A 1 R5 R9 H13 K14 D17 S35 G36 P37 I38 P39 L40 P41 T42 R43 V44 R45 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 D73 K99 R3 R7 H11 K12 D15 S33 G34 P35 I36 P37 L38 P39 T40 R41 V42 R43 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 H60 H66 R68 D71 K97 Q5SHN7 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTV 1vy0 K 3.68 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 G37 N38 P39 W42 S44 G46 G52 S53 K55 R85 V114 P115 H116 N117 G118 C119 R120 K122 K123 K124 K127 Y10 H12 N16 N17 I19 T21 G27 N28 P29 W32 S34 G36 G42 S43 K45 R75 V104 P105 H106 N107 G108 C109 R110 K112 K113 K114 K117 P80376 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 1vy0 L 3.68 BS01 NUC A 1 P5 T6 N8 Q9 R12 K13 R15 E16 K17 K20 K21 K23 K28 G29 A30 P31 F32 R33 R34 P45 K46 K47 P48 N49 S50 A51 L52 R53 K54 T61 Y69 P71 G72 E73 G74 R86 G87 G88 V90 K91 D92 P94 R97 V101 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 R8 K9 R11 E12 K13 K16 K17 K19 K24 G25 A26 P27 F28 R29 R30 P41 K42 K43 P44 N45 S46 A47 L48 R49 K50 T57 Y65 P67 G68 E69 G70 R82 G83 G84 V86 K87 D88 P90 R93 V97 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 Q5SHN3 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 1vy0 M 3.68 BS01 NUC A 1 R14 V17 Y21 I22 Y23 G24 I25 G26 A28 R29 R44 V74 N77 Y87 R88 R91 H92 L96 P97 V98 R99 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 P113 R114 K115 K121 R13 V16 Y20 I21 Y22 G23 I24 G25 A27 R28 R43 V73 N76 Y86 R87 R90 H91 L95 P96 V97 R98 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 P112 R113 K114 K120 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 1vy0 N 3.68 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K9 R12 K15 F16 K17 V18 R19 Y21 T22 C27 R29 R31 S32 V33 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K8 R11 K14 F15 K16 V17 R18 Y20 T21 C26 R28 R30 S31 V32 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 1vy0 O 3.68 BS01 NUC A 1 P2 K5 K8 Q9 I12 F18 D21 T22 G23 S24 T25 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 H53 R54 G55 M58 M59 G61 Q62 R64 R65 R68 Y69 R72 P1 K4 K7 Q8 I11 F17 D20 T21 G22 S23 T24 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 H52 R53 G54 M57 M58 G60 Q61 R63 R64 R67 Y68 R71 Q5SJ76 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 1vy0 P 3.68 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 Y58 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 Y58 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQEA 1vy0 Q 3.68 BS01 NUC A 1 P2 K3 K4 S12 K14 M15 Q16 K17 T18 R25 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 R91 R92 N94 Y95 S97 L98 K100 R101 P1 K2 K3 S11 K13 M14 Q15 K16 T17 R24 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 R90 R91 N93 Y94 S96 L97 K99 R100 Q5SHP7 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKR 1vy0 R 3.68 BS01 NUC A 1 K49 I50 P52 R53 K61 Q63 R64 A67 K68 K71 R72 R74 I75 F81 T82 K31 I32 P34 R35 K43 Q45 R46 A49 K50 K53 R54 R56 I57 F63 T64 Q5SLQ0 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 1vy0 S 3.68 BS01 NUC A 1 P2 R3 S4 L5 K6 K7 V11 H14 W34 R36 R37 Y52 N53 G54 K55 K70 G72 E73 T77 R78 T79 Y80 R81 H83 P1 R2 S3 L4 K5 K6 V10 H13 W33 R35 R36 Y51 N52 G53 K54 K69 G71 E72 T76 R77 T78 Y79 R80 H82 Q5SHP2 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYRGHGK 1vy0 T 3.68 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 N26 K27 A28 K29 S31 K34 T35 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 R80 K81 S82 R83 M85 R86 R89 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 N19 K20 A21 K22 S24 K27 T28 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 R73 K74 S75 R76 M78 R79 R82 G94 G95 G96 L97 S98 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 1vy1 D 3.68 BS01 NUC A 1 K4 K7 P8 Y9 T10 P11 S12 R13 R14 F15 V18 F21 L37 K38 K39 G41 G42 R43 N44 N45 Q46 G47 R48 I49 T50 V51 R52 R54 G56 H58 K59 R60 L61 Y62 R63 I64 K68 Y84 P86 N87 R88 S89 D99 G100 E101 K102 L147 E148 P149 K150 K151 K154 L155 A156 R157 A158 A159 G160 T161 Y172 L177 P178 S179 E181 R183 H186 A199 H201 K202 V205 L206 G207 K208 A209 G210 R211 S212 R213 W214 L215 R217 R218 P219 H220 V221 R222 G223 A224 A225 M226 N227 P228 V229 D230 H231 H233 G235 G236 E237 G238 R239 A240 P241 R242 G243 R244 P245 P246 A247 S248 P249 W250 G251 W252 Q253 T254 K255 G256 L257 K258 T259 R260 R262 R263 K264 P265 S266 R268 F269 I270 K3 K6 P7 Y8 T9 P10 S11 R12 R13 F14 V17 F20 L36 K37 K38 G40 G41 R42 N43 N44 Q45 G46 R47 I48 T49 V50 R51 R53 G55 H57 K58 R59 L60 Y61 R62 I63 K67 Y83 P85 N86 R87 S88 D98 G99 E100 K101 L146 E147 P148 K149 K150 K153 L154 A155 R156 A157 A158 G159 T160 Y171 L176 P177 S178 E180 R182 H185 A198 H200 K201 V204 L205 G206 K207 A208 G209 R210 S211 R212 W213 L214 R216 R217 P218 H219 V220 R221 G222 A223 A224 M225 N226 P227 V228 D229 H230 H232 G234 G235 E236 G237 R238 A239 P240 R241 G242 R243 P244 P245 A246 S247 P248 W249 G250 W251 Q252 T253 K254 G255 L256 K257 T258 R259 R261 R262 K263 P264 S265 R267 F268 I269 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIAR 1vy1 E 3.68 BS01 NUC A 1 K8 M11 T12 R13 P22 Q35 K41 D42 Y44 Q48 R58 N60 R61 P62 K64 H66 R76 L78 R79 E80 R82 S108 K109 G110 R111 G112 F113 A114 G115 M117 K118 R119 N121 F122 A123 G124 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 K154 M156 A157 H159 Y160 E163 R164 V165 T166 M168 L170 K185 A187 V188 P189 G190 P191 K202 K203 K8 M11 T12 R13 P22 Q35 K41 D42 Y44 Q48 R58 N60 R61 P62 K64 H66 R76 L78 R79 E80 R82 S108 K109 G110 R111 G112 F113 A114 G115 M117 K118 R119 N121 F122 A123 G124 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 K154 M156 A157 H159 Y160 E163 R164 V165 T166 M168 L170 K185 A187 V188 P189 G190 P191 K202 K203 Q5SHN8 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKAA 1vy1 E 3.68 BS02 MG E 1 A131 H135 A131 H135 Q5SHN8 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKAA 1vy1 F 3.68 BS01 NUC A 1 N29 H31 W34 E35 R38 W39 Q40 L41 A42 K43 R44 R45 R46 T48 A49 S50 T51 K52 T53 R54 G55 V57 A58 Y59 S60 G61 R62 K63 W65 Q67 K68 H69 G71 R72 R74 H75 G76 I78 P81 I82 F83 V84 G85 V88 V89 F90 P92 P94 R95 Y99 T100 L101 P102 K103 K104 V105 R106 K135 T136 R165 R168 N169 P171 V174 E179 G180 N182 Y184 R188 R205 N24 H26 W29 E30 R33 W34 Q35 L36 A37 K38 R39 R40 R41 T43 A44 S45 T46 K47 T48 R49 G50 V52 A53 Y54 S55 G56 R57 K58 W60 Q62 K63 H64 G66 R67 R69 H70 G71 I73 P76 I77 F78 V79 G80 V83 V84 F85 P87 P89 R90 Y94 T95 L96 P97 K98 K99 V100 R101 K130 T131 R160 R163 N164 P166 V169 E174 G175 N177 Y179 R183 R200 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 1vy1 G 3.68 BS01 NUC A 1 K36 V38 N40 G42 L43 G44 E45 T71 R72 A73 K74 N79 F80 L82 I88 R91 S124 D126 R128 N130 N132 L133 G134 L135 R153 G154 D156 A158 K35 V37 N39 G41 L42 G43 E44 T70 R71 A72 K73 N78 F79 L81 I87 R90 S123 D125 R127 N129 N131 L132 G133 L134 R152 G153 D155 A157 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vy1 G 3.68 BS02 NUC B 1 P2 N27 V28 W29 E30 R33 Q66 K67 P68 A69 V70 T71 R91 V92 T93 R95 R96 R98 P1 N26 V27 W28 E29 R32 Q65 K66 P67 A68 V69 T70 R90 V91 T92 R94 R95 R97 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vy1 H 3.68 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 T70 N74 G108 F109 S110 H111 Q139 G142 Q143 R152 Y157 H158 K160 R170 S1 R2 I3 R58 K61 S62 G65 L66 T69 N73 G107 F108 S109 H110 Q138 G141 Q142 R151 Y156 H157 K159 R169 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRL 1vy1 I 3.68 BS01 NUC A 1 K22 P23 G24 Y25 R27 N28 Y29 R33 S42 K45 A46 R50 R52 A53 K56 R57 K22 P23 G24 Y25 R27 N28 Y29 R33 S42 K45 A46 R50 R52 A53 K56 R57 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 1vy1 N 3.68 BS01 NUC A 1 K2 T3 V5 W13 T22 L23 G24 R25 T28 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 R74 Y75 S76 Y78 P79 G80 L82 K83 K89 R97 E100 H101 A102 G105 M106 P108 K109 P111 L112 R114 F117 K118 K121 P129 Q131 K2 T3 V5 W13 T22 L23 G24 R25 T28 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 R74 Y75 S76 Y78 P79 G80 L82 K83 K89 R97 E100 H101 A102 G105 M106 P108 K109 P111 L112 R114 F117 K118 K121 P129 Q131 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 1vy1 O 3.68 BS01 NUC A 1 M1 Q3 Q5 T6 I22 R23 L25 K26 G27 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K66 K67 E68 K70 R78 N82 M1 Q3 Q5 T6 I22 R23 L25 K26 G27 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K66 K67 E68 K70 R78 N82 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 1vy1 P 3.68 BS01 NUC A 1 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 K17 R18 G20 R21 G22 P23 G24 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 D47 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 R65 G66 M67 Q68 G69 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 A150 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 K17 R18 G20 R21 G22 P23 G24 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 D47 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 R65 G66 M67 Q68 G69 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 A150 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 1vy1 Q 3.68 BS01 NUC A 1 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 T21 K22 G23 Y26 F29 W41 Q46 A49 R56 R59 K63 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 T21 K22 G23 Y26 F29 W41 Q46 A49 R56 R59 K63 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 1vy1 R 3.68 BS01 NUC A 1 M1 R2 H3 L4 K5 S6 R8 K9 L10 N11 R12 H13 S14 S15 H16 R17 L18 A19 L20 R22 N23 Q24 K26 H31 I34 T35 T36 T37 P39 K40 K42 R45 G46 D49 H50 H53 R57 L60 H61 R63 R64 L65 L67 R68 Q71 V73 R77 R90 Q91 G92 G93 T95 R96 V97 K99 R105 G106 D107 A109 V117 M1 R2 H3 L4 K5 S6 R8 K9 L10 N11 R12 H13 S14 S15 H16 R17 L18 A19 L20 R22 N23 Q24 K26 H31 I34 T35 T36 T37 P39 K40 K42 R45 G46 D49 H50 H53 R57 L60 H61 R63 R64 L65 L67 R68 Q71 V73 R77 R90 Q91 G92 G93 T95 R96 V97 K99 R105 G106 D107 A109 V117 Q9Z9H5 MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 1vy1 S 3.68 BS02 NUC B 1 K11 R15 K19 R25 F29 R30 S31 L32 K33 Y36 Q38 I40 G45 V46 T47 S50 S52 L54 A55 K57 N61 K62 T63 Y92 K93 H95 R97 K10 R14 K18 R24 F28 R29 S30 L31 K32 Y35 Q37 I39 G44 V45 T46 S49 S51 L53 A54 K56 N60 K61 T62 Y91 K92 H94 R96 Q5SHQ4 ARLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 1vy1 U 3.68 BS01 NUC A 1 P2 R3 A4 K5 T6 G7 V8 V9 R10 R11 R12 K13 H14 K15 K16 K19 K22 G23 Y24 W25 G26 L27 R28 S29 K30 S31 F32 R33 K34 R36 E37 A41 A42 Y45 Y47 H49 R50 K51 R52 R53 K54 R55 F57 R58 R59 W61 I62 V63 N66 R70 N75 Y76 S77 I80 H81 R92 K93 N94 Q117 P1 R2 A3 K4 T5 G6 V7 V8 R9 R10 R11 K12 H13 K14 K15 K18 K21 G22 Y23 W24 G25 L26 R27 S28 K29 S30 F31 R32 K33 R35 E36 A40 A41 Y44 Y46 H48 R49 K50 R51 R52 K53 R54 F56 R57 R58 W60 I61 V62 N65 R69 N74 Y75 S76 I79 H80 R91 K92 N93 Q116 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQG 1vy1 X 3.68 BS01 NUC A 1 S14 E15 K16 K25 H31 K33 T35 K36 T37 E38 K40 N41 E44 K53 N55 T56 L57 H58 R60 K62 K64 R65 L66 Y69 L70 G71 K72 R73 P74 D75 K78 I80 S12 E13 K14 K23 H29 K31 T33 K34 T35 E36 K38 N39 E42 K51 N53 T54 L55 H56 R58 K60 K62 R63 L64 Y67 L68 G69 K70 R71 P72 D73 K76 I78 Q5SHP0 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEG 1vy1 Y 3.68 BS01 NUC A 1 R2 K4 H6 K8 K9 G18 K19 V30 P32 K34 Y35 I44 V45 K46 K47 V49 V51 G58 G59 F60 H68 S70 K71 R73 R84 V85 R1 K3 H5 K7 K8 G17 K18 V29 P31 K33 Y34 I43 V44 K45 K46 V48 V50 G57 G58 F59 H67 S69 K70 R72 R83 V84 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 1vy1 Z 3.68 BS01 NUC A 1 K46 I120 I146 G147 H151 E168 E169 T170 P176 K46 I120 I146 G147 H151 E168 E169 T170 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vy1 Z 3.68 BS02 NUC B 1 R10 P15 R19 Y29 N30 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 R10 P15 R19 Y29 N30 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vy1 0 3.68 BS01 NUC A 1 H3 K4 G8 S9 T10 R11 N12 R14 D15 S16 Q17 A18 K19 R20 K24 R25 Y26 E27 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 F45 G54 R55 D56 F57 T58 F60 F69 R74 L75 R77 H2 K3 G7 S8 T9 R10 N11 R13 D14 S15 Q16 A17 K18 R19 K23 R24 Y25 E26 Q28 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 F44 G53 R54 D55 F56 T57 F59 F68 R73 L74 R76 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 1vy1 1 3.68 BS01 NUC A 1 S2 K3 K10 I13 V14 A15 N16 I18 Q19 R20 R21 A24 K25 R26 G28 G29 V30 G31 K32 K33 T34 T35 K39 R40 R41 Q42 Y43 P44 N45 Q47 R50 R52 R61 A64 S65 H66 K69 R76 K78 K88 E93 L94 L97 L98 S1 K2 K9 I12 V13 A14 N15 I17 Q18 R19 R20 A23 K24 R25 G27 G28 V29 G30 K31 K32 T33 T34 K38 R39 R40 Q41 Y42 P43 N44 Q46 R49 R51 R60 A63 S64 H65 K68 R75 K77 K87 E92 L93 L96 L97 P60494 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 1vy1 2 3.68 BS01 NUC A 1 S4 E5 R7 L10 R14 K29 Q46 N47 H48 R51 K54 R55 A58 R59 T62 N65 E66 R69 S1 E2 R4 L7 R11 K26 Q43 N44 H45 R48 K51 R52 A55 R56 T59 N62 E63 R66 Q5SHP6 SEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQNA 1vy1 3 3.68 BS01 NUC A 1 K10 S11 I13 G14 Y15 P16 K17 K20 A21 K24 A25 R29 R30 L31 Q32 P41 A42 G45 N46 K49 K9 S10 I12 G13 Y14 P15 K16 K19 A20 K23 A24 R28 R29 L30 Q31 P40 A41 G44 N45 K48 Q5SHQ6 PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE 1vy1 6 3.68 BS01 NUC A 1 V5 R6 K8 L10 R19 Y21 T23 E24 K25 K27 R28 P31 R37 K38 Y39 C40 K45 H46 K53 V1 R2 K4 L6 R15 Y17 T19 E20 K21 K23 R24 P27 R33 K34 Y35 C36 K41 H42 K49 P35871 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVK 1vy1 7 3.68 BS01 NUC A 1 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 R23 P25 G26 G27 R28 K29 V30 K32 R33 R34 R35 Q36 K37 G38 R39 W40 R41 R47 K48 R49 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 R23 P25 G26 G27 R28 K29 V30 K32 R33 R34 R35 Q36 K37 G38 R39 W40 R41 R47 K48 R49 P80340 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRKR 1vy1 8 3.68 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 K12 R13 K15 T17 A18 S19 K21 K26 T27 G28 K29 R30 H31 L32 N33 W34 S37 G38 K39 E40 I41 R42 Q43 K44 R46 K47 F48 K52 L61 L62 Y64 E65 P1 K2 M3 K4 T5 H6 K7 K11 R12 K14 T16 A17 S18 K20 K25 T26 G27 K28 R29 H30 L31 N32 W33 S36 G37 K38 E39 I40 R41 Q42 K43 R45 K46 F47 K51 L60 L61 Y63 E64 Q5SKU1 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 1vy1 9 3.68 BS01 NUC A 1 M1 K2 R4 A5 S6 V7 K8 I10 K15 I17 R18 R19 H20 G21 R22 Y24 I26 P30 K31 K33 R35 Q36 G37 M1 K2 R4 A5 S6 V7 K8 I10 K15 I17 R18 R19 H20 G21 R22 Y24 I26 P30 K31 K33 R35 Q36 G37 Q5SHR2 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 1vy2 B 3.68 BS01 NUC A 1 K22 W24 P26 R96 G99 G100 T103 N104 I108 R111 K133 Y148 I172 E176 K179 K19 W21 P23 R93 G96 G97 T100 N101 I105 R108 K130 Y145 I169 E173 K176 P80371 EITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 1vy2 D 3.68 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 S52 Y54 A55 R59 K61 Q62 R65 R66 S71 E72 R73 Q74 R76 N77 K86 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 D134 L135 P136 S137 L155 E156 L157 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 Q44 R48 S51 Y53 A54 R58 K60 Q61 R64 R65 S70 E71 R72 Q73 R75 N76 K85 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 D133 L134 P135 S136 L154 E155 L156 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 1vy2 E 3.68 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 K47 P49 K57 Y60 Y61 F84 A86 K92 A94 A95 T98 I101 A102 L119 T120 K121 E122 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 K43 P45 K53 Y56 Y57 F80 A82 K88 A90 A91 T94 I97 A98 L115 T116 K117 E118 S121 R122 N123 N126 Y129 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 1vy2 H 3.68 BS01 NUC A 1 M1 L2 T3 P5 D8 T11 R12 R14 N15 R18 V19 K21 S29 R30 F31 K56 K88 P89 G90 R91 R92 Y94 G96 V97 S113 T114 S115 K116 G128 V129 G130 E132 M1 L2 T3 P5 D8 T11 R12 R14 N15 R18 V19 K21 S29 R30 F31 K56 K88 P89 G90 R91 R92 Y94 G96 V97 S113 T114 S115 K116 G128 V129 G130 E132 Q5SHQ2 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 1vy2 K 3.68 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 G37 N38 P39 I40 W42 S44 G46 V47 G52 S53 K55 Y75 R85 P113 V114 H116 N117 G118 C119 R120 P121 K122 K123 K124 Y10 H12 N16 N17 I19 T21 G27 N28 P29 I30 W32 S34 G36 V37 G42 S43 K45 Y65 R75 P103 V104 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 1vy2 M 3.68 BS01 NUC A 1 K13 R14 V17 Y21 I22 Y23 G24 I25 G26 K27 A28 R29 R44 V74 N77 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K121 K12 R13 V16 Y20 I21 Y22 G23 I24 G25 K26 A27 R28 R43 V73 N76 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 K120 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 1vy2 Q 3.68 BS01 NUC A 1 P2 K3 S12 K14 M15 Q16 K17 T18 R25 P28 L31 Y32 K34 R38 S39 K40 K41 Y42 E61 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 R91 R92 N94 Y95 S97 L98 S99 K100 R101 P1 K2 S11 K13 M14 Q15 K16 T17 R24 P27 L30 Y31 K33 R37 S38 K39 K40 Y41 E60 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 R90 R91 N93 Y94 S96 L97 S98 K99 R100 Q5SHP7 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKR 1vy2 S 3.68 BS01 NUC A 1 P2 R3 S4 L5 K6 K7 V11 H14 W34 R36 R37 Y52 N53 G54 K55 K70 G72 E73 T77 R78 Y80 H83 P1 R2 S3 L4 K5 K6 V10 H13 W33 R35 R36 Y51 N52 G53 K54 K69 G71 E72 T76 R77 Y79 H82 Q5SHP2 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYRGHGK 1vy2 T 3.68 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 R22 R23 N26 K27 A28 K29 S31 A32 T35 L36 K39 E51 I55 R57 E60 S61 D64 K65 K68 S70 K74 A78 R79 K81 S82 R83 M85 R89 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 R15 R16 N19 K20 A21 K22 S24 A25 T28 L29 K32 E44 I48 R50 E53 S54 D57 K58 K61 S63 K67 A71 R72 K74 S75 R76 M78 R82 G94 G95 G96 L97 S98 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 1vy3 F 3.68 BS01 NUC A 1 H31 L32 W34 E35 R38 W39 Q40 L41 R44 R45 R46 T48 A49 S50 T51 T53 R54 G55 V57 A58 Y59 S60 G61 R62 K63 W65 P66 Q67 K68 H69 G71 R72 A73 R74 H75 G76 I78 P81 I82 F83 V84 G85 V88 V89 F90 G91 P92 R95 Y99 T100 P102 K103 K104 V105 R106 K108 K135 T136 L140 R165 R168 N169 L170 P171 V174 T175 E179 G180 N182 Y184 H26 L27 W29 E30 R33 W34 Q35 L36 R39 R40 R41 T43 A44 S45 T46 T48 R49 G50 V52 A53 Y54 S55 G56 R57 K58 W60 P61 Q62 K63 H64 G66 R67 A68 R69 H70 G71 I73 P76 I77 F78 V79 G80 V83 V84 F85 G86 P87 R90 Y94 T95 P97 K98 K99 V100 R101 K103 K130 T131 L135 R160 R163 N164 L165 P166 V169 T170 E174 G175 N177 Y179 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 1vy3 G 3.68 BS01 NUC A 1 K36 V38 N40 G42 L43 G44 E45 T71 R72 A73 K74 K75 I77 N79 F80 L82 I88 G89 R91 S124 D126 R128 N130 N132 L133 G134 L135 G154 M155 D156 K35 V37 N39 G41 L42 G43 E44 T70 R71 A72 K73 K74 I76 N78 F79 L81 I87 G88 R90 S123 D125 R127 N129 N131 L132 G133 L134 G153 M154 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vy3 I 3.68 BS01 NUC A 1 K22 P23 G24 Y25 N28 Y29 S42 K45 A46 R50 R52 K22 P23 G24 Y25 N28 Y29 S42 K45 A46 R50 R52 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 1vy3 N 3.68 BS01 NUC A 1 K2 T3 V5 W13 L23 G24 R25 T28 K29 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 R74 Y75 S76 Y78 G80 G81 L82 K83 H94 R97 E100 H101 A102 G105 M106 P108 G110 P111 L112 R114 K118 P129 Q131 K2 T3 V5 W13 L23 G24 R25 T28 K29 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 R74 Y75 S76 Y78 G80 G81 L82 K83 H94 R97 E100 H101 A102 G105 M106 P108 G110 P111 L112 R114 K118 P129 Q131 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 1vy3 O 3.68 BS01 NUC A 1 M1 Q3 Q5 T6 Y7 I22 R23 G27 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K66 K67 E68 K70 R78 N82 M1 Q3 Q5 T6 Y7 I22 R23 G27 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K66 K67 E68 K70 R78 N82 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 1vy3 P 3.68 BS02 MG P 1 Q38 L45 K46 F51 Q38 L45 K46 F51 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 1vy3 Q 3.68 BS02 NUC B 1 R16 L17 K18 A20 R16 L17 K18 A20 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 1vy3 R 3.68 BS01 NUC A 1 M1 R2 H3 L4 K5 S6 R8 K9 N11 R12 H13 S14 S15 H16 R17 A19 L20 R22 N23 Q24 K26 S27 H31 I34 T35 T36 T37 K40 K42 R45 G46 D49 H50 H53 R57 L60 H61 R63 R64 L67 R68 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 A109 M1 R2 H3 L4 K5 S6 R8 K9 N11 R12 H13 S14 S15 H16 R17 A19 L20 R22 N23 Q24 K26 S27 H31 I34 T35 T36 T37 K40 K42 R45 G46 D49 H50 H53 R57 L60 H61 R63 R64 L67 R68 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 A109 Q9Z9H5 MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 1vy3 X 3.68 BS02 MG X 1 F21 K25 Y26 T27 F19 K23 Y24 T25 Q5SHP0 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEG 1vy3 Y 3.68 BS01 NUC A 1 R2 H6 K8 K9 S17 G18 V30 P32 K33 K34 Y35 I44 V45 K46 K47 A48 V49 V51 G58 G59 F60 H68 S70 K71 R73 R84 V85 R1 H5 K7 K8 S16 G17 V29 P31 K32 K33 Y34 I43 V44 K45 K46 A47 V48 V50 G57 G58 F59 H67 S69 K70 R72 R83 V84 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 1vy3 Z 3.68 BS01 NUC A 1 K46 R112 Q118 I146 G147 D148 H151 E169 T170 V175 P176 P177 K46 R112 Q118 I146 G147 D148 H151 E169 T170 V175 P176 P177 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vy3 0 3.68 BS01 NUC A 1 A2 H3 K4 G8 S9 T10 N12 R14 D15 S16 Q17 A18 K19 R20 V23 K24 R25 Y26 E27 G28 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 F45 G54 R55 D56 F57 F60 L62 F69 R74 L75 R77 A1 H2 K3 G7 S8 T9 N11 R13 D14 S15 Q16 A17 K18 R19 V22 K23 R24 Y25 E26 G27 Q28 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 F44 G53 R54 D55 F56 F59 L61 F68 R73 L74 R76 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 1vy3 1 3.68 BS01 NUC A 1 S2 K3 K10 R11 I13 V14 N16 I18 Q19 R20 R21 K25 G28 G29 V30 K32 K33 T34 T35 I37 S38 K39 R40 R41 Q42 Y43 P44 N45 Q47 K48 R50 R52 R61 A64 S65 H66 K69 R76 K78 K88 E93 L97 L98 S1 K2 K9 R10 I12 V13 N15 I17 Q18 R19 R20 K24 G27 G28 V29 K31 K32 T33 T34 I36 S37 K38 R39 R40 Q41 Y42 P43 N44 Q46 K47 R49 R51 R60 A63 S64 H65 K68 R75 K77 K87 E92 L96 L97 P60494 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 1vy3 2 3.68 BS01 NUC A 1 S4 E5 R7 L10 R14 K29 Q46 N47 H48 I50 R51 K54 R55 A58 R59 L61 T62 N65 E66 R69 S1 E2 R4 L7 R11 K26 Q43 N44 H45 I47 R48 K51 R52 A55 R56 L58 T59 N62 E63 R66 Q5SHP6 SEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQNA 1vy3 6 3.68 BS01 NUC A 1 V5 R6 K8 L10 R19 T23 E24 K25 K27 R28 P31 R37 K38 Y39 C40 K45 H46 V1 R2 K4 L6 R15 T19 E20 K21 K23 R24 P27 R33 K34 Y35 C36 K41 H42 P35871 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVK 1vy3 8 3.68 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 K12 R13 K15 T17 A18 S19 K21 K26 T27 G28 K29 R30 H31 L32 N33 W34 Q35 S37 K39 I41 R42 Q43 R46 F48 V49 K52 I58 L61 L62 Y64 E65 P1 K2 M3 K4 T5 H6 K7 K11 R12 K14 T16 A17 S18 K20 K25 T26 G27 K28 R29 H30 L31 N32 W33 Q34 S36 K38 I40 R41 Q42 R45 F47 V48 K51 I57 L60 L61 Y63 E64 Q5SKU1 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 1vy3 9 3.68 BS01 NUC A 1 M1 V3 R4 A5 S6 V7 K8 K15 V16 I17 R18 R19 H20 G21 R22 Y24 I26 P30 K31 K33 R35 Q36 G37 M1 V3 R4 A5 S6 V7 K8 K15 V16 I17 R18 R19 H20 G21 R22 Y24 I26 P30 K31 K33 R35 Q36 G37 Q5SHR2 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 2mgz A BS01 NUC C 1 R101 H103 S105 N106 I107 P108 F109 I131 I132 F133 N134 E135 R136 G137 S138 K139 G140 F141 F143 R167 N172 L173 A174 T175 Q176 R177 R6 H8 S10 N11 I12 P13 F14 I36 I37 F38 N39 E40 R41 G42 S43 K44 G45 F46 F48 R72 N77 L78 A79 T80 Q81 R82 G5EEW7 GDGPRRLHVSNIPFKYREPDLTAMFEKVGPVVDVEIIFNERGSKGFGFVTMQNPDDADRARAEFNGTTIEGRRVEVNLATQRVHNKKAKPLMSV 2mgz B BS01 NUC C 1 F38 G40 Y44 V65 I67 R70 R76 G77 Y78 F80 R103 N106 N108 A110 G113 A114 K115 F20 G22 Y26 V47 I49 R52 R58 G59 Y60 F62 R85 N88 N90 A92 G95 A96 K97 O45189 GSTNAEPVVGSRDTMFTKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKDPNPIIDGRKANVNLAYLGAKPRTNVQLA 2mow A BS01 III B 1 K21 S25 G26 R28 I29 K30 Y67 D70 S71 R74 M126 L127 I130 K21 S25 G26 R28 I29 K30 Y67 D70 S71 R74 M126 L127 I130 P53617 25066235 MQQDDDFQNFVATLESFKDLKSGISGSRIKKLTTYALDHIDIESKIISLIIDYSRLCPDSHKLGSLYIIDSIGRAYLDETRSNSNSSSNKPGTCAHAINTLGEVIQELLSDAIAKSNQDHKEKIRMLLDIWDRSGLFQKSYLNAIRSKCFAMDLEHHHHHH 2ru3 A BS01 NUC B 1 K36 F38 G40 G41 L42 P43 Y44 I67 D69 R70 K74 R76 G77 Y78 F80 R103 K104 N106 N108 A110 G113 A114 K115 R117 K18 F20 G22 G23 L24 P25 Y26 I49 D51 R52 K56 R58 G59 Y60 F62 R85 K86 N88 N90 A92 G95 A96 K97 R99 O45189 GSTNAEPVVGSRDTMFTKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKDPNPIIDGRKANVNLAYLGAKPRTNVQ 3wgg A 2.10 BS01 8NA A 1 I90 G93 N94 L95 D117 I118 N119 C153 I154 P155 N158 T162 F177 P179 I87 G90 N91 L92 D114 I115 N116 C150 I151 P152 N155 T159 F174 P176 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLK 3wgg A 2.10 BS02 8NA B 1 N101 Y102 T103 S104 N98 Y99 T100 S101 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLK 3wgg B 2.10 BS02 8NA B 1 I90 G93 N94 L95 D117 I118 N119 L122 C153 I154 P155 F177 P179 I87 G90 N91 L92 D114 I115 N116 L119 C150 I151 P152 F174 P176 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLK 3wgh A 2.05 BS01 NAI A 1 I90 G93 N94 L95 D117 I118 N119 C153 I154 P155 T162 F177 L178 V193 L195 I80 G83 N84 L85 D107 I108 N109 C143 I144 P145 T152 F167 L168 V183 L185 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLK 3wgh A 2.05 BS02 NAI B 1 A98 Y102 A88 Y92 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLK 3wgh B 2.05 BS02 NAI B 1 I90 G93 N94 L95 D117 I118 L122 C153 I154 P155 T162 F177 V193 L195 I81 G84 N85 L86 D108 I109 L113 C144 I145 P146 T153 F168 V184 L186 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLK 3wgi A 3.25 BS01 NUC E 1 S34 S35 R50 N54 G58 F59 G60 Q62 G63 Y64 G65 Y66 S31 S32 R47 N51 G55 F56 G57 Q59 G60 Y61 G62 Y63 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA 3wgi A 3.25 BS02 NUC F 1 S8 R14 T45 S47 Q48 R50 Q51 Q61 Q62 S5 R11 T42 S44 Q45 R47 Q48 Q58 Q59 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA 3wgi A 3.25 BS03 NAJ A 1 I90 G91 A92 G93 N94 L95 D117 I118 N119 V135 C153 I154 P155 F177 P179 L195 I87 G88 A89 G90 N91 L92 D114 I115 N116 V132 C150 I151 P152 F174 P176 L192 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA 3wgi A 3.25 BS04 NAJ B 1 A98 I99 Y102 F105 A95 I96 Y99 F102 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA 3wgi B 3.25 BS01 NUC E 1 S8 A10 R14 T45 S47 Q48 R50 Q51 Q61 Q62 S5 A7 R11 T42 S44 Q45 R47 Q48 Q58 Q59 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA 3wgi B 3.25 BS04 NAJ B 1 I90 G91 G93 N94 L95 D117 I118 N119 C153 I154 P155 T162 F177 L178 P179 L195 S196 I87 G88 G90 N91 L92 D114 I115 N116 C150 I151 P152 T159 F174 L175 P176 L192 S193 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA 3wgi C 3.25 BS02 NUC H 1 S8 R14 T45 S47 Q48 R50 Q51 Q62 S5 R11 T42 S44 Q45 R47 Q48 Q59 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA 3wgi C 3.25 BS04 NAJ D 1 I99 Y102 F105 I96 Y99 F102 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA 3wgi D 3.25 BS02 NUC H 1 S34 S35 R50 Q51 N54 G58 F59 G60 Q61 Q62 G63 Y64 G65 Y66 S31 S32 R47 Q48 N51 G55 F56 G57 Q58 Q59 G60 Y61 G62 Y63 D5KM69 KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETA 3wrx A 2.50 BS01 AGS A 1 T16 D18 T19 K20 S54 T55 S56 R92 A95 G124 S125 G126 G127 T9 D11 T12 K13 S44 T45 S46 R82 A85 G114 S115 G116 G117 A7M6E7 SPRVFCIGTADTKFDELRFLSEHVRSSLNSFSNKKVGVTVVDVSTSWKETNSCADFDFVPSKDVLSCHTLGEETMGTFADIRGLAIAIMSKALETFLSIANDEQNLAGVIGLGGSGGTSLLSSAFRSLPIGIPKVIISTVASGQTESYIGTSDLVLFPSVVDICGINNVSKVVLSNAGAAFAGMVIGRLESKFTVGVTMFGVTTPCVNAVKERLVKEGYETLVFHATGVGGRAMEDLVRGGFIQGVLDITTTEVADYVVGGVMACDSSRFDAILEKKIPLVLSVGALDMVNFGPKTTIPPEFQQRKIHEHNEQVSLMRTTVGENKKFAAFIAEKLNKASSSVCVCLPEKGVSALDAPGKDFYDPEATSCLTRELQMLLENNERCQVKVLPYHINDAEFANALVDSFLEISPK 3wrx A 2.50 BS02 MG A 1 M85 G86 M75 G76 A7M6E7 SPRVFCIGTADTKFDELRFLSEHVRSSLNSFSNKKVGVTVVDVSTSWKETNSCADFDFVPSKDVLSCHTLGEETMGTFADIRGLAIAIMSKALETFLSIANDEQNLAGVIGLGGSGGTSLLSSAFRSLPIGIPKVIISTVASGQTESYIGTSDLVLFPSVVDICGINNVSKVVLSNAGAAFAGMVIGRLESKFTVGVTMFGVTTPCVNAVKERLVKEGYETLVFHATGVGGRAMEDLVRGGFIQGVLDITTTEVADYVVGGVMACDSSRFDAILEKKIPLVLSVGALDMVNFGPKTTIPPEFQQRKIHEHNEQVSLMRTTVGENKKFAAFIAEKLNKASSSVCVCLPEKGVSALDAPGKDFYDPEATSCLTRELQMLLENNERCQVKVLPYHINDAEFANALVDSFLEISPK 3wrx C 2.50 BS01 AGS A 1 D1097 R1100 V1101 D418 R421 V422 2.1.1.-,2.7.7.-,3.6.4.13 P03587 SEEIESLEQFHMATASSLIHKQMCSIVYTGPLKVQQMKNFIDSLVASLSAAVSNLVKILKDKFGVLDVASKRWLVKPSAKNHAWGVVETHARKYHVALLEHDEFGIITCDNWRRVAVSSESVVYSDMAKLRTLRRLLKDGEPHVSSAKVVLVDGVPGCGKTKEILSRVNFEEDLILVPGRQAAEMIRRRANASGIIVATKDNVRTVDSFLMNYGKGARCQFKRLFIDEGLMLHTGCVNFLVEMSLCDIAYVYGDTQQIPYINRVTGFPYPAHFAKLEVDEVETRRTTLRCPADVTHFLNQRYEGHVMCTSSEKKSVSQEMVSGAASINPVSKPLKGKILTFTQSDKEALLSRGYADVHTVHEVQGETYADVSLVRLTPTPVSIIARDSPHVLVSLSRHTKSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDA 3wrx C 2.50 BS02 MG A 1 N978 Y981 G983 N299 Y302 G304 2.1.1.-,2.7.7.-,3.6.4.13 P03587 SEEIESLEQFHMATASSLIHKQMCSIVYTGPLKVQQMKNFIDSLVASLSAAVSNLVKILKDKFGVLDVASKRWLVKPSAKNHAWGVVETHARKYHVALLEHDEFGIITCDNWRRVAVSSESVVYSDMAKLRTLRRLLKDGEPHVSSAKVVLVDGVPGCGKTKEILSRVNFEEDLILVPGRQAAEMIRRRANASGIIVATKDNVRTVDSFLMNYGKGARCQFKRLFIDEGLMLHTGCVNFLVEMSLCDIAYVYGDTQQIPYINRVTGFPYPAHFAKLEVDEVETRRTTLRCPADVTHFLNQRYEGHVMCTSSEKKSVSQEMVSGAASINPVSKPLKGKILTFTQSDKEALLSRGYADVHTVHEVQGETYADVSLVRLTPTPVSIIARDSPHVLVSLSRHTKSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDA 3wrx C 2.50 BS03 AGS C 1 P835 G836 C837 G838 K839 T840 K841 R868 Q936 L967 R968 G1044 T1046 R1076 P156 G157 C158 G159 K160 T161 K162 R189 Q257 L288 R289 G365 T367 R397 2.1.1.-,2.7.7.-,3.6.4.13 P03587 SEEIESLEQFHMATASSLIHKQMCSIVYTGPLKVQQMKNFIDSLVASLSAAVSNLVKILKDKFGVLDVASKRWLVKPSAKNHAWGVVETHARKYHVALLEHDEFGIITCDNWRRVAVSSESVVYSDMAKLRTLRRLLKDGEPHVSSAKVVLVDGVPGCGKTKEILSRVNFEEDLILVPGRQAAEMIRRRANASGIIVATKDNVRTVDSFLMNYGKGARCQFKRLFIDEGLMLHTGCVNFLVEMSLCDIAYVYGDTQQIPYINRVTGFPYPAHFAKLEVDEVETRRTTLRCPADVTHFLNQRYEGHVMCTSSEKKSVSQEMVSGAASINPVSKPLKGKILTFTQSDKEALLSRGYADVHTVHEVQGETYADVSLVRLTPTPVSIIARDSPHVLVSLSRHTKSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDA 3wry D 2.30 BS02 AGS D 1 P835 G836 C837 G838 K839 T840 K841 R867 R868 R968 G1044 T1046 R1076 P155 G156 C157 G158 K159 T160 K161 R187 R188 R288 G364 T366 R396 2.1.1.-,2.7.7.-,3.6.4.13 P03587 SLEQFHMATASSLIHKQMCSIVYTGPLKVQQMKNFIDSLVASLSAAVSNLVKILKLETRQKFGVLDVASKRWLVKPSAKNHAWGVVETHARKYHVALLEHDEFGIITCDNWRRVAVSSESVVYSDMAKLRTLRRLLKDGEPHVSSAKVVLVDGVPGCGKTKEILSRVNFEEDLILVPGRQAAEMIRRRANASGIIVATKDNVRTVDSFLMNYGKGARCQFKRLFIDEGLMLHTGCVNFLVEMSLCDIAYVYGDTQQIPYINRVTGFPYPAHFAKLEVDEVETRRTTLRCPADVTHFLNQRYEGHVMCTSSEKKSVSQEMVSGAASINPVSKPLKGKILTFTQSDKEALLSRGYADVHTVHEVQGETYADVSLVRLTPTPVSIIARDSPHVLVSLSRHTKSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVD 3wts A 2.35 BS01 NUC D 1 H78 R139 R142 G143 K167 T169 V170 D171 R177 H20 R81 R84 G85 K109 T111 V112 D113 R119 Q03347 25083921 MGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVAKGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPR 3wts C 2.35 BS01 NUC D 1 Q336 L337 W375 K379 K381 K383 M384 K388 R391 Y395 Y396 Q18 L19 W57 K61 K63 K65 M66 K70 R73 Y77 Y78 P14921 25083921 PVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK 3wts C 2.35 BS02 NUC E 1 G333 P334 R391 R394 Y395 Y397 K404 K408 R409 Y410 G15 P16 R73 R76 Y77 Y79 K86 K90 R91 Y92 P14921 25083921 PVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK 3wts H 2.35 BS01 NUC I 1 Q336 L337 W375 K379 K381 K388 R391 Y395 Y396 Q4 L5 W43 K47 K49 K56 R59 Y63 Y64 P14921 25083921 GPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAML 3wts H 2.35 BS02 NUC J 1 P334 R391 R394 Y395 Y397 K404 R409 P2 R59 R62 Y63 Y65 K72 R77 P14921 25083921 GPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAML 3wtt C 2.35 BS01 NUC D 1 Q336 L337 W375 K379 K383 M384 K388 R391 Y396 Q18 L19 W57 K61 K65 M66 K70 R73 Y78 P14921 25083921 PVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK 3wtt H 2.35 BS01 NUC I 1 Q336 L337 W375 K379 K381 M384 K388 Y395 Y396 K399 Q4 L5 W43 K47 K49 M52 K56 Y63 Y64 K67 P14921 25083921 GPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYT 3wtu A 2.70 BS01 NUC D 1 H78 R139 R142 G143 K167 T169 A170 D171 R177 H19 R80 R83 G84 K108 T110 A111 D112 R118 Q03347 25083921 GELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVAKGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITADGPREPR 3wtu F 2.70 BS01 NUC I 1 R139 R142 G143 K167 T169 A170 D171 R177 R80 R83 G84 K108 T110 A111 D112 R118 Q03347 25083921 GELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVAKGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITADGPREPR 3wtu H 2.70 BS01 NUC I 1 Q336 L337 W375 K379 K381 K388 Y395 Y396 K399 Q4 L5 W43 K47 K49 K56 Y63 Y64 K67 P14921 25083921 GPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAML 3wtx C 2.80 BS02 NUC E 1 P334 R391 R394 Y395 Y397 K404 K408 R409 Y410 P1 R58 R61 Y62 Y64 K71 K75 R76 Y77 P14921 25083921 PIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK 3wty C 2.70 BS02 NUC E 1 S332 P334 R391 R394 Y395 Y397 K404 K408 R409 Y410 S14 P16 R73 R76 Y77 Y79 K86 K90 R91 Y92 P14921 25083921 PVIPAAALAGYTGSPPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK 3wty H 2.70 BS01 NUC I 1 Q336 L337 W375 K379 K388 R391 Y395 Y396 K399 Q4 L5 W43 K47 K56 R59 Y63 Y64 K67 P14921 25083921 PPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAML 4by4 A 2.30 BS01 CA A 1 D73 N75 D77 A79 E84 D68 N70 D72 A74 E79 Q9VWX8 25074811 SKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQNTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALS 4by4 A 2.30 BS02 CA A 2 D109 D111 D113 Y115 E120 D104 D106 D108 Y110 E115 Q9VWX8 25074811 SKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQNTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALS 4by4 A 2.30 BS03 CA A 3 D156 N158 D160 R162 E167 D144 N146 D148 R150 E155 Q9VWX8 25074811 SKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQNTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALS 4by4 B 2.30 BS01 CA B 1 D73 N75 D77 A79 I80 E84 D69 N71 D73 A75 I76 E80 Q9VWX8 25074811 NSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALS 4bzd A 1.83 BS01 D6I A 1 K9 I10 V18 A31 V64 F80 E81 F82 L83 H84 D86 Q131 L134 D145 K9 I10 V17 A30 V57 F73 E74 F75 L76 H77 D79 Q124 L127 D138 2.7.11.22 P24941 MENFQKVEKIGEGYGVVYKARNKLTGEVVALKKIRLVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 4bzf A 1.90 BS01 TRE A 1 S76 T79 P205 N290 N293 L294 S75 T78 P204 N289 N292 L293 5.1.3.3 P39840 ANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTNVQLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFLYHEKWNVVTTKQTDEGVIVETEIDLSELPHVQKQFPHHAVVRMTYTIKENTLFKHATVMNKGKEAFPWGIGYHTTFIFPAESSLFSLTADQQWELDERLLPTGKLMDVPYKEALHEGMDLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFKHWVVYNADGKQGYLCPEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELN 4bzf B 1.90 BS01 TRE B 1 S76 T79 L204 P205 N290 N293 L294 S75 T78 L203 P204 N289 N292 L293 5.1.3.3 P39840 ANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTNVQLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFLYHEKWNVVTTKQTDEGVIVETEIDLSELPHVQKQFPHHAVVRMTYTIKENTLFKHATVMNKGKEAFPWGIGYHTTFIFPAESSLFSLTADQQWELDERLLPTGKLMDVPYKEALHEGMDLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFKHWVVYNADGKQGYLCPEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNH 4bzg A 2.13 BS01 MAL A 1 T62 N73 R74 E93 L100 H101 H177 L203 D230 Y271 E283 T61 N72 R73 E92 L99 H100 H176 L202 D229 Y270 E282 5.1.3.3 P39840 ANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTNVQLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFLYHEKWNVVTTKQTDEGVIVETEIDLSELPHVQKQFPHHAVVRMTYTIKENTLFKHATVMNKGKEAFPWGIGYHTTFIFPAESSLFSLTADQQWELDERLLPTGKLMDVPYKEALHEGMDLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFKHWVVYNADGKQGYLCPEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELN 4bzg B 2.13 BS01 MAL B 1 L63 N73 R74 E93 H101 H177 D230 Y271 E283 L62 N72 R73 E92 H100 H176 D229 Y270 E282 5.1.3.3 P39840 ANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTNVQLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFLYHEKWNVVTTKQTDEGVIVETEIDLSELPHVQKQFPHHAVVRMTYTIKENTLFKHATVMNKGKEAFPWGIGYHTTFIFPAESSLFSLTADQQWELDERLLPTGKLMDVPYKEALHEGMDLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFKHWVVYNADGKQGYLCPEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNH 4bzh B 2.60 BS01 TRE B 1 S76 D77 T79 L204 P205 N290 N293 S75 D76 T78 L203 P204 N289 N292 5.1.3.3 P39840 ANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTNVQLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFLYHEKWNVVTTKQTDEGVIVETEIDLSELPHVQKQFPHHAVVRMTYTIKENTLFKHATVMNKGKEAFPWGIGYHTTFIFPAESSLFSLTADQQWELDERLLPTGKLMDVPYKEALHEGMDLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFKHWVVYNADGKQGYLCPEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNH 4bzq A 2.10 BS01 ADX A 1 D480 R483 F492 R497 N500 L501 A522 I523 S524 P525 K562 L564 H575 F576 T577 D41 R44 F53 R58 N61 L62 A83 I84 S85 P86 K123 L125 H136 F137 T138 2.7.7.4,2.7.1.25 P9WNM4 PPRGKTVWFTGLSGSGKSSVAMLVERKLLEKGISAYVLDGDNLRHGLNADLGFSMADRAENLRRLSHVATLLADCGHLVLVPAISPLAEHRALARKVHADAGIDFFEVFCDTPLQDCERRDPKGLYAKARAGEITHFTGIDSPYQRPKNPDLRLTPDRSIDEQAQEVIDLLES 4bzq A 2.10 BS02 ADP A 1 G453 S454 G455 K456 S457 S458 R559 P561 R597 I599 Q602 G14 S15 G16 K17 S18 S19 R120 P122 R158 I160 Q163 2.7.7.4,2.7.1.25 P9WNM4 PPRGKTVWFTGLSGSGKSSVAMLVERKLLEKGISAYVLDGDNLRHGLNADLGFSMADRAENLRRLSHVATLLADCGHLVLVPAISPLAEHRALARKVHADAGIDFFEVFCDTPLQDCERRDPKGLYAKARAGEITHFTGIDSPYQRPKNPDLRLTPDRSIDEQAQEVIDLLES 4bzx A 1.70 BS02 ANP A 1 S452 G453 S454 G455 K456 S457 S458 I523 R559 P561 K562 R597 I599 Q602 S13 G14 S15 G16 K17 S18 S19 I84 R120 P122 K123 R158 I160 Q163 2.7.1.25 P9WNM4 PPRGKTVWFTGLSGSGKSSVAMLVERKLLEKGISAYVLDGDNLRHGLNADLGFSMADRAENLRRLSHVATLLADCGHLVLVPAISPLAEHRALARKVHADAGIDFFEVFCDTPLQDCERRDPKGLYAKARAGEITHFTGIDSPYQRPKNPDLRLTPDRSIDEQAQEVIDLLES 4bzx B 1.70 BS01 ADX B 1 R483 F492 R497 N500 L501 A522 I523 S524 P525 L564 H575 F576 T577 R44 F53 R58 N61 L62 A83 I84 S85 P86 L125 H136 F137 T138 2.7.1.25 P9WNM4 PPRGKTVWFTGLSGSGKSSVAMLVERKLLEKGISAYVLDGDNLRHGLNADLGFSMADRAENLRRLSHVATLLADCGHLVLVPAISPLAEHRALARKVHADAGIDFFEVFCDTPLQDCERRDPKGLYAKARAGEITHFTGIDSPYQRPKNPDLRLTPDRSIDEQAQEVIDLLES 4c1n A 2.53 BS01 SF4 A 1 P13 K15 N16 C17 K18 E19 C20 C25 F28 C42 P43 P12 K14 N15 C16 K17 E18 C19 C24 F27 C41 P42 Q3ACS3 GLTGLEIYKHLPKKNCKECGQPTCLAFAMQIAAGKAGLDACPYVSDEAKELLESASAPPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQRW 4c1n A 2.53 BS02 B12 I 1 F337 I338 T339 F342 T345 C348 V349 G369 T370 S371 V372 L373 T374 A378 I405 P407 P429 R430 E431 S432 F336 I337 T338 F341 T344 C347 V348 G368 T369 S370 V371 L372 T373 A377 I404 P406 P428 R429 E430 S431 Q3ACS3 GLTGLEIYKHLPKKNCKECGQPTCLAFAMQIAAGKAGLDACPYVSDEAKELLESASAPPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQRW 4c1n G 2.53 BS01 SF4 G 1 L12 P13 N16 C17 K18 E19 C20 C25 F28 C42 P43 L10 P11 N14 C15 K16 E17 C18 C23 F26 C40 P41 Q3ACS3 LTGLEIYKHLPKKNCKECGQPTCLAFAMQIAAGKAGLDACPYVSDEAKELLESASAPPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQRW 4c1n G 2.53 BS02 B12 K 1 F337 I338 T339 F342 T345 V349 G369 T370 S371 V372 L373 T374 I405 P407 P429 R430 E431 S432 F335 I336 T337 F340 T343 V347 G367 T368 S369 V370 L371 T372 I403 P405 P427 R428 E429 S430 Q3ACS3 LTGLEIYKHLPKKNCKECGQPTCLAFAMQIAAGKAGLDACPYVSDEAKELLESASAPPVALIKVGKGEKVLEIGHETVLFRHDKRFEHPCGLAILVEDTLSEGEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKGLDALAELVQKITALGYKNLILDPQPENISEGLFYQTQIRRLAIKKLFRPFGYPTIAFALDENPYQAVMEASVYIAKYAGIIVLNTVEPADILPLITLRLNIYTDPQKPIAVEPKVYEILNPGPDAPVFITTNFSLTYFCVAGDVEGARIPAYILPVDTDGTSVLTAWAAGKFTPEKIAQFLKESGIAEKVNHRKAILPGGVAVLSGKLQELSGWEILVGPRESSGINSFIKQRW 4c1n I 2.53 BS01 B12 I 1 D246 I248 Y318 Y352 T380 N381 S398 A399 G400 P401 N509 R512 A513 E602 L603 S604 F609 M610 F613 D125 I127 Y197 Y231 T259 N260 S277 A278 G279 P280 N388 R391 A392 E481 L482 S483 F488 M489 F492 Q3ACS2 LDPLFKEVSLELPVPTLDDPRDDLSRLTATFSRQENGNLIVEYEQLKDLPQILRNENFSVTVGVSDYLGLNKALYIKSGSASQRVFGLAIDIGTTTVVVQLVDLVSGKVLGTKGNYNKQAAFGDDVISRIIYVDENPDGAEKLRKAVLSTINELIFQLCKEHGVEKKEIMAAVVAGNTTMTHLFLEIDPRYIRLEPYTPAALFIPPVPATEAKIEMNPKGFVYIMPNVASYVGGDITSGVLYTGLANSDEITLFIDIGTNGEMVLGNKDWLVTCACSAGPAFEGSGIKHGMRAMQGAIERVSISEAGLKVKYQTVGGIPPVGICGSGLIDLLANLKRAGIIDRSGKIDRTVNKERIREGEDGLEFVLAWANESGNNKDIVITEADIQNLIRAKAAIFAGVRTMLAMVDLPLEAIDRVIIAGGFGKYLNIKDAITIGLLPDIDINKFSYVGNSSLKGARKALLSRKACAEVKEIARKMTYLELSVGTTFMDEFVSASFIPHTDLHLFPSV 4c1n J 2.53 BS01 B12 C 1 D246 I248 Y318 Y352 T380 N381 S398 A399 G400 P401 N509 R512 A513 A516 E602 F609 M610 F613 D125 I127 Y197 Y231 T259 N260 S277 A278 G279 P280 N388 R391 A392 A395 E481 F488 M489 F492 Q3ACS2 LDPLFKEVSLELPVPTLDDPRDDLSRLTATFSRQENGNLIVEYEQLKDLPQILRNENFSVTVGVSDYLGLNKALYIKSGSASQRVFGLAIDIGTTTVVVQLVDLVSGKVLGTKGNYNKQAAFGDDVISRIIYVDENPDGAEKLRKAVLSTINELIFQLCKEHGVEKKEIMAAVVAGNTTMTHLFLEIDPRYIRLEPYTPAALFIPPVPATEAKIEMNPKGFVYIMPNVASYVGGDITSGVLYTGLANSDEITLFIDIGTNGEMVLGNKDWLVTCACSAGPAFEGSGIKHGMRAMQGAIERVSISEAGLKVKYQTVGGIPPVGICGSGLIDLLANLKRAGIIDRSGKIDRTVNKERIREGEDGLEFVLAWANESGNNKDIVITEADIQNLIRAKAAIFAGVRTMLAMVDLPLEAIDRVIIAGGFGKYLNIKDAITIGLLPDIDINKFSYVGNSSLKGARKALLSRKACAEVKEIARKMTYLELSVGTTFMDEFVSASFIPHTDLHLFPSV 4cth A 2.15 BS02 RDF A 1 F106 V541 N542 A543 F544 I558 F563 H583 E584 H587 E646 W693 V710 H711 R717 F54 V489 N490 A491 F492 I506 F511 H531 E532 H535 E594 W641 V658 H659 R665 3.4.24.11 P08473 25089527 DGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYVTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPKNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 4cwv A 2.34 BS01 HEM A 1 W180 R185 C186 S228 M341 F355 S356 W358 M360 E363 W449 F475 Y477 W102 R107 C108 S150 M263 F277 S278 W280 M282 E285 W371 F397 Y399 1.14.13.39 P29473 25089924 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cwv A 2.34 BS03 HW8 A 1 V338 N340 M341 W358 E363 W449 Y477 V260 N262 M263 W280 E285 W371 Y399 1.14.13.39 P29473 25089924 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cwv B 2.34 BS04 HW8 B 1 L107 V338 N340 M341 W358 E363 W449 Y477 L39 V258 N260 M261 W278 E283 W369 Y397 1.14.13.39 P29473 25089924 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cww A 2.16 BS03 HW9 A 1 P336 V338 N340 M341 F355 S356 G357 W358 E363 W449 Y477 P259 V261 N263 M264 F278 S279 G280 W281 E286 W372 Y400 1.14.13.39 P29473 25089924 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cwx A 2.15 BS03 HW0 A 1 V106 P336 V338 N340 M341 W358 Y359 E363 W449 Y477 V40 P258 V260 N262 M263 W280 Y281 E285 W371 Y399 1.14.13.39 P29473 25089924 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cwx B 2.15 BS04 HW0 B 1 V106 L107 P336 V338 N340 M341 W358 E363 W449 Y477 V38 L39 P256 V258 N260 M261 W278 E283 W369 Y397 1.14.13.39 P29473 25089924 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cwy A 2.15 BS03 HW1 A 1 V106 P336 V338 N340 M341 F355 G357 W358 Y359 E363 W449 Y477 V40 P258 V260 N262 M263 F277 G279 W280 Y281 E285 W371 Y399 1.14.13.39 P29473 25089924 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cwy B 2.15 BS04 HW1 B 1 V106 L107 P336 V338 N340 M341 F355 G357 W358 Y359 E363 W449 Y477 V38 L39 P256 V258 N260 M261 F275 G277 W278 Y279 E283 W369 Y397 1.14.13.39 P29473 25089924 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cwz A 2.08 BS01 HEM A 1 W180 R185 C186 V187 S228 M341 F355 S356 W358 E363 W449 F475 W103 R108 C109 V110 S151 M264 F278 S279 W281 E286 W372 F398 1.14.13.39 P29473 25089924 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRAQPDPW 4cwz A 2.08 BS03 HW9 A 1 L107 P336 V338 M341 F355 G357 W358 E363 W449 A477 L41 P259 V261 M264 F278 G280 W281 E286 W372 A400 1.14.13.39 P29473 25089924 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRAQPDPW 4cwz B 2.08 BS03 HEM B 1 W180 C186 V187 G188 S228 M341 F355 S356 G357 W358 M360 E363 W449 F475 W102 C108 V109 G110 S150 M263 F277 S278 G279 W280 M282 E285 W371 F397 1.14.13.39 P29473 25089924 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRAQPDPW 4cwz B 2.08 BS05 HW9 B 1 V106 P336 V338 M341 F355 S356 G357 W358 E363 W449 A477 V38 P258 V260 M263 F277 S278 G279 W280 E285 W371 A399 1.14.13.39 P29473 25089924 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRAQPDPW 4cx0 A 2.20 BS03 Q16 A 1 V106 R185 V338 F355 W358 Y359 E363 V40 R108 V261 F278 W281 Y282 E286 1.14.13.39 P29473 25089924 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRAQPDPW 4cx0 B 2.20 BS03 HEM B 1 W180 C186 V187 S228 F355 S356 G357 W358 M360 E363 W449 F475 W101 C107 V108 S149 F276 S277 G278 W279 M281 E284 W370 F396 1.14.13.39 P29473 25089924 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRAQPDPW 4cx0 B 2.20 BS05 Q16 B 1 V106 L107 R185 P336 V338 F355 W358 Y359 E363 V38 L39 R106 P257 V259 F276 W279 Y280 E284 1.14.13.39 P29473 25089924 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRAQPDPW 4cx1 B 2.13 BS02 HEM B 1 W180 R185 C186 V187 G188 L195 S228 M341 F355 S356 G357 W358 M360 E363 V420 W449 F475 Y477 W102 R107 C108 V109 G110 L117 S150 M263 F277 S278 G279 W280 M282 E285 V342 W371 F397 Y399 1.14.13.39 P29473 25089924 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cx2 A 2.04 BS01 HEM A 1 W180 C186 V187 G188 S228 M341 F355 S356 W358 M360 E363 V420 W449 F475 Y477 W103 C109 V110 G111 S151 M264 F278 S279 W281 M283 E286 V343 W372 F398 Y400 1.14.13.39 P29473 25089924 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4cx3 A 1.97 BS01 HEM A 1 W409 A412 R414 C415 V416 G417 S457 M570 F584 S585 G586 W587 M589 E592 W678 F704 W100 A103 R105 C106 V107 G108 S148 M261 F275 S276 G277 W278 M280 E283 W369 F395 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIVLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRNYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4cx3 A 1.97 BS03 HW8 A 1 V336 L337 R414 Q478 P565 V567 W587 E592 W678 Y706 V38 L39 R105 Q169 P256 V258 W278 E283 W369 Y397 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIVLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRNYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4cx3 B 1.97 BS04 HW8 B 1 V336 L337 R414 Q478 P565 V567 W587 E592 Y706 V38 L39 R107 Q171 P258 V260 W280 E285 Y399 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIVLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRNYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4cx4 A 1.98 BS03 HW9 A 1 V336 L337 R414 Q478 P565 V567 F584 G586 W587 E592 W678 Y706 V38 L39 R105 Q169 P256 V258 F275 G277 W278 E283 W369 Y397 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIVLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRNYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4cx4 B 1.98 BS02 HEM B 1 W409 A412 R414 C415 V416 S457 M570 F584 S585 G586 W587 E592 W678 F704 W102 A105 R107 C108 V109 S150 M263 F277 S278 G279 W280 E285 W371 F397 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIVLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRNYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4cx4 B 1.98 BS04 HW9 B 1 V336 L337 R414 P565 V567 F584 S585 G586 W587 E592 Y706 V38 L39 R107 P258 V260 F277 S278 G279 W280 E285 Y399 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIVLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRNYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4cx5 A 1.80 BS01 HEM A 1 W409 C415 V416 G417 S457 F584 S585 G586 W587 M589 E592 W678 F704 W100 C106 V107 G108 S148 F275 S276 G277 W278 M280 E283 W369 F395 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4cx5 A 1.80 BS03 HW8 A 1 M336 L337 R414 Q478 P565 V567 W587 E592 W678 Y706 M38 L39 R105 Q169 P256 V258 W278 E283 W369 Y397 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4cx5 B 1.80 BS03 HEM B 1 W409 A412 C415 V416 G417 S457 M570 F584 S585 G586 W587 E592 W678 F704 W102 A105 C108 V109 G110 S150 M263 F277 S278 G279 W280 E285 W371 F397 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4cx6 A 1.90 BS03 Q16 A 1 M336 L337 R414 P565 V567 F584 W587 E592 Y706 M38 L39 R105 P256 V258 F275 W278 E283 Y397 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4cx6 B 1.90 BS03 HEM B 1 W409 A412 C415 V416 G417 S457 F584 S585 W587 E592 W678 F704 W102 A105 C108 V109 G110 S150 F277 S278 W280 E285 W371 F397 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4cx6 B 1.90 BS05 Q16 B 1 M336 L337 R414 V567 F584 W587 E592 W678 Y706 M38 L39 R107 V260 F277 W280 E285 W371 Y399 1.14.13.39 P29476 25089924 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4cx7 A 3.16 BS01 HEM A 1 W194 C200 I201 G202 Q205 S242 F369 N370 G371 W372 E377 W463 Y489 Y491 W105 C111 I112 G113 Q116 S153 F280 N281 G282 W283 E288 W374 Y400 Y402 1.14.13.39 P35228 25089924 RHVRIKNWGSGMTFQDTLHHKAKGICLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQ 4cx7 A 3.16 BS03 S71 A 1 M120 T121 Q263 P350 V352 W372 E377 Y491 M31 T32 Q174 P261 V263 W283 E288 Y402 1.14.13.39 P35228 25089924 RHVRIKNWGSGMTFQDTLHHKAKGICLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQ 4cx7 B 3.16 BS04 S71 B 1 M120 Q263 R266 P350 V352 W372 E377 W463 Y491 M31 Q174 R177 P261 V263 W283 E288 W374 Y402 1.14.13.39 P35228 25089924 RHVRIKNWGSGMTFQDTLHHKAKGICLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQ 4cx7 C 3.16 BS03 S71 C 1 M120 T121 Q263 P350 V352 W372 E377 W463 Y491 M31 T32 Q174 P261 V263 W283 E288 W374 Y402 1.14.13.39 P35228 25089924 RHVRIKNWGSGMTFQDTLHHKAKGICLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQ 4cx7 D 3.16 BS02 HEM D 1 W194 C200 I201 G202 Q205 F369 N370 G371 W372 E377 W463 Y491 W105 C111 I112 G113 Q116 F280 N281 G282 W283 E288 W374 Y402 1.14.13.39 P35228 25089924 RHVRIKNWGSGMTFQDTLHHKAKGICLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQ 4czm A 2.20 BS01 ANP A 1 G18 T19 A20 N21 G164 G165 G166 T167 G188 E213 K216 K217 G294 G295 G296 L298 L299 L321 G10 T11 A12 N13 G156 G157 G158 T159 G180 E205 K208 K209 G286 G287 G288 L290 L291 L313 B8H609 24843005 ISNDIAIDLGTANTLIYQKGKGIVLNEPSVVALRNVGGRKVVHAVGIEAKQMLGRTPGHMEAIRPMRDGVIADFEVAEEMIKYFIRKVHNRKGSGNPKVIVCVPSGATAVERRAINDSCLNAGARRVGLIDEPMAAAIGAGLPIHEPTGSMVVDIGGGTTEVAVLSLSGIVYSRSVRVGGDKMDEAIISYMRRHHNLLIGETTAERIKKEIGTARAPADGEGLSIDVKGRDLMQGVPREVRISEKQAADALAEPVGQIVEAVKVALEATPPELADDIADKGIMLTGGGALLRGLDAEIRDHTGLPVTVADDPLSCVALGCGKVLEHPKWMKGVLES 4kyi B 3.08 BS01 GNP B 1 S30 A31 V32 G33 K34 S35 S36 F46 H47 E48 S52 T53 G79 N134 K135 D137 L138 S164 A165 K166 S12 A13 V14 G15 K16 S17 S18 F28 H29 E30 S34 T35 G61 N116 K117 D119 L120 S146 A147 K148 P51148 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGLERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 4kyi B 3.08 BS02 MG B 1 S35 T53 D76 S17 T35 D58 P51148 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGLERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 4kyi D 3.08 BS01 GNP D 1 S30 A31 G33 K34 S35 S36 F46 H47 E48 S52 T53 G79 N134 K135 D137 L138 S164 A165 S12 A13 G15 K16 S17 S18 F28 H29 E30 S34 T35 G61 N116 K117 D119 L120 S146 A147 P51148 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGLERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 4kyi F 3.08 BS01 GNP F 1 S30 A31 V32 G33 K34 S35 S36 F46 E48 S52 T53 N134 K135 D137 S164 A165 K166 S12 A13 V14 G15 K16 S17 S18 F28 E30 S34 T35 N116 K117 D119 S146 A147 K148 P51148 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGLERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKL 4m4g A 2.70 BS01 SAC A 1 T100 H101 T102 Q103 T149 F201 G203 T225 T15 H16 T17 Q18 T64 F116 G118 T140 P06614 EHTWPDKGSLYIATTHTQARYALPGVIKGFIERYPRVSLHMHQGSPTQIAEAVSKGNADFAIATEALHLYDDLVMLPCYHWNRSIVVTPDHPLAATSSVTIEALAQYPLVTYTFGFTGRSELDTAFNRAGLTPRIVFTATDADVIKTYVRLGLGVGVIASMAVDPLADPDLVRIDAHDIFSHSTTKIGFRRSTFLRSYMYDFIQRFAPHLTRDVVDTAVALRSNEEIEAMFQDIKLPEK 4m4g A 2.70 BS02 SAC A 2 A107 K324 A22 K239 P06614 EHTWPDKGSLYIATTHTQARYALPGVIKGFIERYPRVSLHMHQGSPTQIAEAVSKGNADFAIATEALHLYDDLVMLPCYHWNRSIVVTPDHPLAATSSVTIEALAQYPLVTYTFGFTGRSELDTAFNRAGLTPRIVFTATDADVIKTYVRLGLGVGVIASMAVDPLADPDLVRIDAHDIFSHSTTKIGFRRSTFLRSYMYDFIQRFAPHLTRDVVDTAVALRSNEEIEAMFQDIKLPEK 4mgj A 2.41 BS01 HEM A 1 R98 V113 I114 W121 R125 M132 A298 G299 T303 T306 I363 V367 H369 L392 P428 H429 S430 R434 C436 L437 G438 I441 A442 R63 V78 I79 W86 R90 M97 A259 G260 T264 T267 I324 V328 H330 L353 P389 H390 S391 R395 C397 L398 G399 I402 A403 1.14.14.1 P00178 25029089 GKLPPGPSPLPVLGNLLQMFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFELFPGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPHSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFLAR 4mgj A 2.41 BS02 CPZ A 1 I101 F297 A298 T302 V367 V477 I66 F258 A259 T263 V328 V438 1.14.14.1 P00178 25029089 GKLPPGPSPLPVLGNLLQMFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFELFPGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPHSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFLAR 4mim A 2.65 BS02 BPV A 1 R548 D549 Q552 G586 L619 R621 F654 K718 H749 T882 R78 D79 Q82 G116 L149 R151 F184 K248 H279 T412 6.4.1.1 Q2K340 24157795 DRATKLLTYLADVTVNGHPEAKDRPKPLENAARPVVPYANGNGVKDGTKQLLDTLGPKKFGEWMRNEKRVLLTDTTMRDGHQSLLATRMRTYDIARIAGTYSHALPNLLSLECWGGATFDVSMRFLTEDPWERLALIREGAPNLLLQMLLRGANGVGYTNYPDNVVKYFVRQAAKGGIDLFRVFDCLNWVENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTNLAVELEKAGAHIIAVKDMAGLLKPAAAKVLFKALREATGLPIHFHTHDTSGIAAATVLAAVEAGVDAVDAAMDALSGNTSQPCLGSIVEALSGSERDPGLDPAWIRRISFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHQVAQAYADANQMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVVSPDREVSFPESVVSMLKGDLGQPPSGWPEALQKKALKGEKPYTVRPGSLLKEADLDAERKVIEKKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLADGEELFADIEKTLVIVNQAVSATDSQGMVTVFFELNGQPRRIKVPDRA 4mim B 2.65 BS03 BPV B 1 R548 D549 Q552 G586 L619 R621 F654 K718 T882 R75 D76 Q79 G113 L146 R148 F181 K245 T409 6.4.1.1 Q2K340 24157795 DRATKLLTYLADVTVNGHPEAKDRPKPLENARPVVPYANGVKDGTKQLLDTLGPKKFGEWMRNEKRVLLTDTTMRDGHQSLLATRMRTYDIARIAGTYSHALPNLLSLECWGGATFDVSMRFLTEDPWERLALIREGAPNLLLQMLLRGANGVGYTNYPDNVVKYFVRQAAKGGIDLFRVFDCLNWVENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTNLAVELEKAGAHIIAVKDMAGLLKPAAAKVLFKALREATGLPIHFHTHDTSGIAAATVLAAVEAGVDAVDAAMDALSGNTSQPCLGSIVEALSGSERDPGLDPAWIRRISFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHQVAQAYADANQMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVVSPDREVSFPESVVSMLKGDLGQPPSGWPEALQKKALKEKPYTVRPGSLLKEADLDAERKVIEKKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLADGEELFADIEKGKTLVIVNQAVSATDSQGMVTVFFELNGQPRRIKVPDRA 4mim C 2.65 BS02 BPV C 1 R548 Q552 G586 L619 R621 F654 K718 V881 T882 R78 Q82 G116 L149 R151 F184 K248 V411 T412 6.4.1.1 Q2K340 24157795 DRATKLLTYLADVTVNGHPEAKDRPKPLENAARPVVPYANGNGVKDGTKQLLDTLGPKKFGEWMRNEKRVLLTDTTMRDGHQSLLATRMRTYDIARIAGTYSHALPNLLSLECWGGATFDVSMRFLTEDPWERLALIREGAPNLLLQMLLRGANGVGYTNYPDNVVKYFVRQAAKGGIDLFRVFDCLNWVENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTNLAVELEKAGAHIIAVKDMAGLLKPAAAKVLFKALREATGLPIHFHTHDTSGIAAATVLAAVEAGVDAVDAAMDALSGNTSQPCLGSIVEALSGSERDPGLDPAWIRRISFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHQVAQAYADANQMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVVSPDREVSFPESVVSMLKGDLGQPPSGWPEALQKKALKGEKPYTVRPGSLLKEADLDAERKVIEKKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLADGEELFADIEKGKTLVIVNQAVSATDSQGMVTVFFELNGQPRRIKVPDRA 4mwm A 1.12 BS01 CPT A 1 H15 V92 N93 K96 H15 V92 N93 K96 3.2.1.17 P00698 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGC 4mwm A 1.12 BS03 MEB A 1 Y20 R21 Y20 R21 3.2.1.17 P00698 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGC 4ndo B 1.35 BS01 ATP B 1 K42 G44 G45 Q46 S47 G77 A78 G79 T169 K189 D190 G193 Y195 A197 N198 P199 K200 S224 I225 K40 G42 G43 Q44 S45 G75 A76 G77 T167 K187 D188 G191 Y193 A195 N196 P197 K198 S222 I223 P84253 24945101 NSTAELEELLMQRSLTDPQLQAAAAAAADFRILPDATVIKIGGQSVIDRGRAAVYPLVDEIVAARKNHKLLIGTGAGTRARHLYSIAAGLGLPAGVLAQLGSSVADQNAAMLGQLLAKHGIPVVGGAGLSAVPLSLAEVNAVVFSGMPPYKLWMRPAAEGVIPPYRTDAGCFLLAEQFGCKQMIFVKDEDGLYTANPKTSKDATFIPRISVDEMKAKGLHDSILEFPVLDLLQSAQHVREVQVVNGLVPGNLTRALAGEHVGTIITAS 4ndo B 1.35 BS02 8M0 B 1 G127 G128 A129 G130 F146 S147 M149 P151 L176 F180 G125 G126 A127 G128 F144 S145 M147 P149 L174 F178 P84253 24945101 NSTAELEELLMQRSLTDPQLQAAAAAAADFRILPDATVIKIGGQSVIDRGRAAVYPLVDEIVAARKNHKLLIGTGAGTRARHLYSIAAGLGLPAGVLAQLGSSVADQNAAMLGQLLAKHGIPVVGGAGLSAVPLSLAEVNAVVFSGMPPYKLWMRPAAEGVIPPYRTDAGCFLLAEQFGCKQMIFVKDEDGLYTANPKTSKDATFIPRISVDEMKAKGLHDSILEFPVLDLLQSAQHVREVQVVNGLVPGNLTRALAGEHVGTIITAS 4ndo A 1.35 BS04 8M0 A 1 P103 A106 S107 G110 Q111 H114 Y127 E129 H130 P131 S150 P154 H156 P72 A75 S76 G79 Q80 H83 Y96 E98 H99 P100 S119 P123 H125 P84308 24945101 KRPIRLLPWLQVVKIGGRVMDRGADAILPLVEELRKLLPEHRLLILTGAGVRARHVFSVGLDLGLPVGSLAPLAASEAGQNGHILAAMLASEGVSYVEHPTVADQLAIHLSATRAVVGSAFPPYHHHEFPGSRIPPHRADTGAFLLADAFGAAGLTIVENVDGIYTADPNGPDRGQARFLPETSATDLAKSEGPLPVDRALLDVMATARHIERVQVVNGLVPGRLTAALRGEHVGTLIRTGVRPA 4ndp B 1.60 BS01 ATP B 1 K42 G44 G45 Q46 S47 G77 A78 G79 T169 K189 D190 E191 G193 L194 Y195 A197 N198 P199 K200 S224 I225 K40 G42 G43 Q44 S45 G75 A76 G77 T167 K187 D188 E189 G191 L192 Y193 A195 N196 P197 K198 S222 I223 P84253 24945101 NSTAELEELLMQRSLTDPQLQAAAAAAADFRILPDATVIKIGGQSVIDRGRAAVYPLVDEIVAARKNHKLLIGTGAGTRARHLYSIAAGLGLPAGVLAQLGSSVADQNAAMLGQLLAKHGIPVVGGAGLSAVPLSLAEVNAVVFSGMPPYKLWMRPAAEGVIPPYRTDAGCFLLAEQFGCKQMIFVKDEDGLYTANPKTSKDATFIPRISVDEMKAKGLHDSILEFPVLDLLQSAQHVREVQVVNGLVPGNLTRALAGEHVGTIITAS 4ndp A 1.60 BS05 M10 A 1 Q136 H140 Q105 H109 P84308 24945101 KRPIRLLPWLQVVKIGGRVMDRGADAILPLVEELRKLLPEHRLLILTGAGVRARHVFSVGLDLGLPVGSLAPLAASEAGQNGHILAAMLASEGVSYVEHPTVADQLAIHLSATRAVVGSAFPPYHHHEFPGSRIPPHRADTGAFLLADAFGAAGLTIVENVDGIYTADPNGPDRGQARFLPETSATDLAKSEGPLPVDRALLDVMATARHIERVQVVNGLVPGRLTAALRGEHVGTLIRTGVRPA 4ndq B 1.75 BS01 ATP B 1 K42 G44 G45 Q46 S47 G77 G79 K189 D190 E191 G193 Y195 A197 N198 P199 K200 S224 I225 K40 G42 G43 Q44 S45 G75 G77 K187 D188 E189 G191 Y193 A195 N196 P197 K198 S222 I223 P84253 24945101 NSTAELEELLMQRSLTDPQLQAAAAAAADFRILPDATVIKIGGQSVIDRGRAAVYPLVDEIVAARKNHKLLIGTGAGTRARHLYSIAAGLGLPAGVLAQLGSSVADQNAAMLGQLLAKHGIPVVGGAGLSAVPLSLAEVNAVVFSGMPPYKLWMRPAAEGVIPPYRTDAGCFLLAEQFGCKQMIFVKDEDGLYTANPKTSKDATFIPRISVDEMKAKGLHDSILEFPVLDLLQSAQHVREVQVVNGLVPGNLTRALAGEHVGTIITAS 4ndq B 1.75 BS02 8M0 B 1 G127 G130 L131 F146 S147 M149 P151 L176 F180 G125 G128 L129 F144 S145 M147 P149 L174 F178 P84253 24945101 NSTAELEELLMQRSLTDPQLQAAAAAAADFRILPDATVIKIGGQSVIDRGRAAVYPLVDEIVAARKNHKLLIGTGAGTRARHLYSIAAGLGLPAGVLAQLGSSVADQNAAMLGQLLAKHGIPVVGGAGLSAVPLSLAEVNAVVFSGMPPYKLWMRPAAEGVIPPYRTDAGCFLLAEQFGCKQMIFVKDEDGLYTANPKTSKDATFIPRISVDEMKAKGLHDSILEFPVLDLLQSAQHVREVQVVNGLVPGNLTRALAGEHVGTIITAS 4ndq B 1.75 BS03 MO B 1 A133 S137 A131 S135 P84253 24945101 NSTAELEELLMQRSLTDPQLQAAAAAAADFRILPDATVIKIGGQSVIDRGRAAVYPLVDEIVAARKNHKLLIGTGAGTRARHLYSIAAGLGLPAGVLAQLGSSVADQNAAMLGQLLAKHGIPVVGGAGLSAVPLSLAEVNAVVFSGMPPYKLWMRPAAEGVIPPYRTDAGCFLLAEQFGCKQMIFVKDEDGLYTANPKTSKDATFIPRISVDEMKAKGLHDSILEFPVLDLLQSAQHVREVQVVNGLVPGNLTRALAGEHVGTIITAS 4ndq A 1.75 BS01 8M0 B 1 Y155 H156 H157 H158 Y124 H125 H126 H127 P84308 24945101 KRPIRLLPWLQVVKIGGRVMDRGADAILPLVEELRKLLPEHRLLILTGAGVRARHVFSVGLDLGLPVGSLAPLAASEAGQNGHILAAMLASEGVSYVEHPTVADQLAIHLSATRAVVGSAFPPYHHHEFPGSRIPPHRADTGAFLLADAFGAAGLTIVENVDGIYTADPNGPDRGQARFLPETSATDLAKSEGPLPVDRALLDVMATARHIERVQVVNGLVPGRLTAALRGEHVGTLIRTGVRPA 4ndq A 1.75 BS03 MG A 1 D171 P227 D140 P196 P84308 24945101 KRPIRLLPWLQVVKIGGRVMDRGADAILPLVEELRKLLPEHRLLILTGAGVRARHVFSVGLDLGLPVGSLAPLAASEAGQNGHILAAMLASEGVSYVEHPTVADQLAIHLSATRAVVGSAFPPYHHHEFPGSRIPPHRADTGAFLLADAFGAAGLTIVENVDGIYTADPNGPDRGQARFLPETSATDLAKSEGPLPVDRALLDVMATARHIERVQVVNGLVPGRLTAALRGEHVGTLIRTGVRPA 4ndq A 1.75 BS04 8M0 A 1 A106 S107 G110 H114 Y127 E129 H130 P131 S150 P153 P154 H156 A75 S76 G79 H83 Y96 E98 H99 P100 S119 P122 P123 H125 P84308 24945101 KRPIRLLPWLQVVKIGGRVMDRGADAILPLVEELRKLLPEHRLLILTGAGVRARHVFSVGLDLGLPVGSLAPLAASEAGQNGHILAAMLASEGVSYVEHPTVADQLAIHLSATRAVVGSAFPPYHHHEFPGSRIPPHRADTGAFLLADAFGAAGLTIVENVDGIYTADPNGPDRGQARFLPETSATDLAKSEGPLPVDRALLDVMATARHIERVQVVNGLVPGRLTAALRGEHVGTLIRTGVRPA 4ndr A 2.00 BS05 M10 A 1 T132 Q136 H140 T101 Q105 H109 P84308 24945101 KRPIRLLPWLQVVKIGGRVMDRGADAILPLVEELRKLLPEHRLLILTGAGVRARHVFSVGLDLGLPVGSLAPLAASEAGQNGHILAAMLASEGVSYVEHPTVADQLAIHLSATRAVVGSAFPPYHHHEFPGSRIPPHRADTGAFLLADAFGAAGLTIVENVDGIYTADPNGPDRGQARFLPETSATDLAKSEGPLPVDRALLDVMATARHIERVQVVNGLVPGRLTAALRGEHVGTLIRTGVRPA 4ny2 A 1.88 BS01 ZN A 1 D40 H97 H101 D11 H68 H72 3.5.1.41 M7M1G8 24810719 PKGTIYLTFDDGPVNASVEVIKVLNQGGVKATFYFNAWHLDGIGDENEDRALEALKLALDSGHIVGNHSYDHMIHNCVEEFGPTSGADCNATGNHQIHSYQDPVRDAASFEQNLITLEKYLPTIRSYPNYKGYELARLPYTNGWRVTKHFQADGLCATSDNLKPWEPGYVCDPANPSNSVKASIQVQNILANQGYQTHGWDVDWAPENWGIPMPANSLTEAVPFLAYVDKALNSCSPTTIEPINSKTQEFPCGTPLHADKVIVLTHDFLFEDGKRGMGATQNLPKLAEFIRIAKEAGYVFDTMDNYTPRWSVGKTYQAGEYVLYQGVVYKAVISHTAQQDWAPSSTSSLWTNADPATNWTLNVSYEQGDIVNYKGKRYLVSVPHVSQQDWTPDTQNTLFTALEL 4ny4 A 2.95 BS01 HEM A 1 R105 I118 S119 W126 R130 F137 F302 A305 T309 V313 I369 A370 L373 R375 P434 F435 G436 R440 N441 C442 I443 A448 M452 R78 I91 S92 W99 R103 F110 F264 A267 T271 V275 I331 A332 L335 R337 P396 F397 G398 R402 N403 C404 I405 A410 M414 1.14.13.-,1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.97 P08684 24642031 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQFLQLMIDSQSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 4ny4 A 2.95 BS02 2QH A 1 R105 R106 F108 S119 R212 F213 F215 F241 I301 F304 A305 T309 A370 R78 R79 F81 S92 R185 F186 F188 F214 I263 F266 A267 T271 A332 1.14.13.-,1.14.13.157,1.14.13.32,1.14.13.67,1.14.13.97 P08684 24642031 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQFLQLMIDSQSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDG 4nz1 A 2.05 BS02 NAG A 1 D40 H101 N119 H124 R304 D11 H72 N90 H95 R275 3.5.1.41 M7M1G8 24810719 PKGTIYLTFSDGPVNASVEVIKVLNQGGVKATFYFNAWHLDGIGDENEDRALEALKLALDSGHIVGNHSYDHMIHNCVEEFGPTSGADCNATGNHQIHSYQDPVRDAASFEQNLITLEKYLPTIRSYPNYKGYELARLPYTNGWRVTKHFQADGLCATSDNLKPWEPGYVCDPANPSNSVKASIQVQNILANQGYQTHGWDVDWAPENWGIPMPANSLTEAVPFLAYVDKALNSCSPTTIEPINSKTQEFPCGTPLHADKVIVLTHDFLFEDGKRGMGATQNLPKLAEFIRIAKEAGYVFDTMDNYTPRWSVGKTYQAGEYVLYQGVVYKAVISHTAQQDWAPSSTSSLWTNADPATNWTLNVSYEQGDIVNYKGKRYLVSVPHVSQQDWTPDTQNTLFTALE 4nz1 A 2.05 BS03 NAG A 2 D40 H101 Q125 P168 Y169 W238 H295 D11 H72 Q96 P139 Y140 W209 H266 3.5.1.41 M7M1G8 24810719 PKGTIYLTFSDGPVNASVEVIKVLNQGGVKATFYFNAWHLDGIGDENEDRALEALKLALDSGHIVGNHSYDHMIHNCVEEFGPTSGADCNATGNHQIHSYQDPVRDAASFEQNLITLEKYLPTIRSYPNYKGYELARLPYTNGWRVTKHFQADGLCATSDNLKPWEPGYVCDPANPSNSVKASIQVQNILANQGYQTHGWDVDWAPENWGIPMPANSLTEAVPFLAYVDKALNSCSPTTIEPINSKTQEFPCGTPLHADKVIVLTHDFLFEDGKRGMGATQNLPKLAEFIRIAKEAGYVFDTMDNYTPRWSVGKTYQAGEYVLYQGVVYKAVISHTAQQDWAPSSTSSLWTNADPATNWTLNVSYEQGDIVNYKGKRYLVSVPHVSQQDWTPDTQNTLFTALE 4nz2 A 2.45 BS01 HEM A 1 R97 I112 V113 W120 R124 L294 A297 G298 T301 T302 Q356 L361 L362 S365 L366 H368 P427 F428 S429 R433 C435 V436 G437 L440 A441 R71 I86 V87 W94 R98 L268 A271 G272 T275 T276 Q330 L335 L336 S339 L340 H342 P401 F402 S403 R407 C409 V410 G411 L414 A415 1.14.13.-,1.14.13.80,1.14.13.48,1.14.13.49 P11712 24642031 KGRPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIEILSSPWIQVYNNFPALLDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV 4nz2 A 2.45 BS02 2QJ A 1 N107 F114 I205 L208 L233 V237 G296 E300 T301 T304 L362 L366 A477 N81 F88 I179 L182 L207 V211 G270 E274 T275 T278 L336 L340 A451 1.14.13.-,1.14.13.80,1.14.13.48,1.14.13.49 P11712 24642031 KGRPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIEILSSPWIQVYNNFPALLDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV 4nz2 B 2.45 BS02 2QJ B 1 N107 F114 I205 L208 V237 G296 E300 T301 T304 L362 A477 N81 F88 I179 L182 V211 G270 E274 T275 T278 L336 A451 1.14.13.-,1.14.13.80,1.14.13.48,1.14.13.49 P11712 24642031 KGRPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIEILSSPWIQVYNNFPALLDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV 4nz3 A 2.11 BS03 NAG A 2 D40 H97 H101 Q125 P168 Y169 W238 H295 D11 H68 H72 Q96 P139 Y140 W209 H266 3.5.1.41 M7M1G8 24810719 PKGTIYLTFSDGPVNASVEVIKVLNQGGVKATFYFNAWHLDGIGDENEDRALEALKLALDSGHIVGNHSYDHMIHNCVEEFGPTSGADCNATGNHQIHSYQDPVRDAASFEQNLITLEKYLPTIRSYPNYKGYELARLPYTNGWRVTKHFQADGLCATSDNLKPWEPGYVCDPANPSNSVKASIQVQNILANQGYQTHGWDVDWAPENWGIPMPANSLTEAVPFLAYVDKALNSCSPTTIEPINSKTQEFPCGTPLHADKVIVLTHDFLFEDGKRGMGATQNLPKLAEFIRIAKEAGYVFDTMDNYTPRWSVGKTYQAGEYVLYQGVVYKAVISHTAQQDWAPSSTSSLWTNADPATNWTLNVSYEQGDIVNYKGKRYLVSVPHVSQQDWTPDTQNTLFTALE 4nz3 B 2.11 BS03 NAG B 2 S39 D40 H97 H101 Q125 P168 Y169 W238 H295 S10 D11 H68 H72 Q96 P139 Y140 W209 H266 3.5.1.41 M7M1G8 24810719 PKGTIYLTFSDGPVNASVEVIKVLNQGGVKATFYFNAWHLDGIGDENEDRALEALKLALDSGHIVGNHSYDHMIHNCVEEFGPTSGADCNATGNHQIHSYQDPVRDAASFEQNLITLEKYLPTIRSYPNYKGYELARLPYTNGWRVTKHFQADGLCATSDNLKPWEPGYVCDPANPSNSVKASIQVQNILANQGYQTHGWDVDWAPENWGIPMPANSLTEAVPFLAYVDKALNSCSPTTIEPINSKTQEFPCGTPLHADKVIVLTHDFLFEDGKRGMGATQNLPKLAEFIRIAKEAGYVFDTMDNYTPRWSVGKTYQAGEYVLYQGVVYKAVISHTAQQDWAPSSTSSLWTNADPATNWTLNVSYEQGDIVNYKGKRYLVSVPHVSQQDWTPDTQNTLFTALE 4o0l A 2.20 BS01 NDP A 1 G35 G38 G39 I40 R60 S61 A62 C85 E86 V87 N113 A114 G115 V137 T164 T165 S166 Y181 K185 P210 G211 F212 F213 T215 P216 M217 G218 G29 G32 G33 I34 R54 S55 A56 C79 E80 V81 N107 A108 G109 V131 T158 T159 S160 Y175 K179 P204 G205 F206 F207 T209 P210 M211 G212 B9ZZZ6 24507746 GPFPKATPQLPNSVFDMFSMKGKVTAITGGGGGIGFAAAEAIAEAGGDVALLYRSAPNMEERSAELAKRFGVKVKSYQCEVTEHESVKQAIEAVEKDFGRLDCYIANAGGGVPGSINPDYPLEAWHKTQSVNLHSTFYAARECARIFKAQGSGSFIATTSISARIVNVPYDQPAYNSSKAAVVHFCRSLARDWRNFARVNTISPGFFDTPMGPSDKAVEDVLYQKSVLGRAGDVKELKAAYLYLASNASTYTTGADLLIDGGYCLT 4o4s A 2.50 BS01 CYC A 1 V36 Q55 Y65 R66 R68 N83 L113 C116 M118 C137 V139 R141 L148 F152 F159 S161 D163 W175 F182 F184 V35 Q54 Y64 R65 R67 N82 L112 C115 M117 C136 V138 R140 L147 F151 F158 S160 D162 W174 F181 F183 4.-.-.- Q8YLF9 THSTDIATLARWMAADFSNQAQAFENPPFYAHIRVCMRPLPWEVLSGVGFFVEQAYDYMLNDPYRLRVLKLMIVGDRIHIENYTVKQEENFYGASRDLNRLQTLTSESLEKLPGCNMIVEWTGNSFKGTVEPGKGCIVVRKGQKTYLDSEFEINEEKFISLDRGRDLETDAHIWGSVAGPFYFVRLHNFADEVKISAEL 4o4s B 2.50 BS01 CYC B 1 Q55 R66 R68 N83 L113 C116 M118 C137 V139 R141 L148 F152 F159 S161 D163 W175 F182 Q54 R65 R67 N82 L112 C115 M117 C136 V138 R140 L147 F151 F158 S160 D162 W174 F181 4.-.-.- Q8YLF9 THSTDIATLARWMAADFSNQAQAFENPPFYAHIRVCMRPLPWEVLSGVGFFVEQAYDYMLNDPYRLRVLKLMIVGDRIHIENYTVKQEENFYGASRDLNRLQTLTSESLEKLPGCNMIVEWTGNSFKGTVEPGKGCIVVRKGQKTYLDSEFEINEEKFISLDRGRDLETDAHIWGSVAGPFYFVRLHNFADEVKISA 4o4s I 2.50 BS02 CYC J 1 P28 F30 P27 F29 4.-.-.- Q8YLF9 THSTDIATLARWMAADFSNQAQAFENPPFYAHIRVCMRPLPWEVLSGVGFFVEQAYDYMLNDPYRLRVLKLMIVGDRIHIENYTVKQEENFYGASRDLNRLQTLTSESLEKLPGCNMIVEWTGNSFKGTVEPGKGCIVVRKGQKTYLDSEFEINEEKFISLDRGRDLETDAHIWGSVAGPFYFVRLHNFADEVKISA 4o4s J 2.50 BS01 CYC J 1 Q55 R66 R68 L70 N83 L113 C116 M118 C137 R141 L148 F152 F159 S161 D163 W175 F182 F184 Q54 R65 R67 L69 N82 L112 C115 M117 C136 R140 L147 F151 F158 S160 D162 W174 F181 F183 4.-.-.- Q8YLF9 THSTDIATLARWMAADFSNQAQAFENPPFYAHIRVCMRPLPWEVLSGVGFFVEQAYDYMLNDPYRLRVLKLMIVGDRIHIENYTVKQEENFYGASRDLNRLQTLTSESLEKLPGCNMIVEWTGNSFKGTVEPGKGCIVVRKGQKTYLDSEFEINEEKFISLDRGRDLETDAHIWGSVAGPFYFVRLHNFADEVKISA 4o4s D 2.50 BS01 CYC D 1 V36 Q55 R66 R68 L70 N83 L113 C116 M118 C137 V139 R141 L148 F152 F159 D163 W175 F182 F184 V35 Q54 R65 R67 L69 N82 L112 C115 M117 C136 V138 R140 L147 F151 F158 D162 W174 F181 F183 4.-.-.- Q8YLF9 THSTDIATLARWMAADFSNQAQAFENPPFYAHIRVCMRPLPWEVLSGVGFFVEQAYDYMLNDPYRLRVLKLMIVGDRIHIENYTVKQEENFYGASRDLNRLQTLTSESLEKLPGCNMIVEWTGNSFKGTVEPGKGCIVVRKGQKTYLDSEFEINEEKFISLDRGRDLETDAHIWGSVAGPFYFVRLHNFADEVKISA 4o4s H 2.50 BS01 CYC H 1 I34 V36 Q55 R66 R68 N83 L113 C116 M118 C137 V139 R141 L148 F152 F159 S161 D163 W175 F182 F184 I33 V35 Q54 R65 R67 N82 L112 C115 M117 C136 V138 R140 L147 F151 F158 S160 D162 W174 F181 F183 4.-.-.- Q8YLF9 THSTDIATLARWMAADFSNQAQAFENPPFYAHIRVCMRPLPWEVLSGVGFFVEQAYDYMLNDPYRLRVLKLMIVGDRIHIENYTVKQEENFYGASRDLNRLQTLTSESLEKLPGCNMIVEWTGNSFKGTVEPGKGCIVVRKGQKTYLDSEFEINEEKFISLDRGRDLETDAHIWGSVAGPFYFVRLHNFADEVKISA 4o9w A 1.69 BS01 III B 1 K413 W414 V415 D416 Y485 H489 L490 L491 R516 H538 K540 K39 W40 V41 D42 Y111 H115 L116 L117 R133 H155 K157 2.7.11.21 P53350 HLSDMLQQLHSVNASKPSELVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR 4obz A 2.90 BS01 2S4 B 1 D33 Y78 S80 D32 Y77 S79 3.4.23.5 P07339 25086681 PIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQS 4obz B 2.90 BS01 2S4 B 1 T125 F131 I134 Y205 I229 D231 G233 T234 I311 I320 T19 F25 I28 Y99 I123 D125 G127 T128 I205 I214 3.4.23.5 P07339 25086681 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEAA 4oc6 A 2.64 BS01 2S1 B 1 A13 D33 G35 H77 Y78 G79 S80 A13 D33 G35 H77 Y78 G79 S80 3.4.23.5 P07339 25086681 GPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQS 4oc6 B 2.64 BS01 2S1 B 1 T125 F131 I134 I142 Y205 I229 D231 G233 T234 S235 E260 I311 S315 I320 T20 F26 I29 I37 Y100 I124 D126 G128 T129 S130 E155 I206 S210 I215 3.4.23.5 P07339 25086681 GGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEAARL 4od9 A 1.90 BS01 2RZ A 1 A13 D33 G35 Y78 G79 S80 A12 D32 G34 Y77 G78 S79 3.4.23.5 P07339 25086681 PIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQS 4od9 B 1.90 BS01 2RZ A 1 T125 F126 F131 I134 Y205 I229 D231 G233 T234 M309 I311 I320 T19 F20 F25 I28 Y99 I123 D125 G127 T128 M203 I205 I214 3.4.23.5 P07339 25086681 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEAA 4od9 C 1.90 BS01 2RZ D 1 A13 D33 G35 Y78 G79 A12 D32 G34 Y77 G78 3.4.23.5 P07339 25086681 PIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQS 4oql A 2.10 BS01 F2U A 1 H58 E83 W88 I97 Y101 Q125 M128 Y132 R163 A167 A168 Y172 R222 E225 H13 E35 W40 I49 Y53 Q77 M80 Y84 R110 A114 A115 Y119 R169 E172 2.7.1.21 P03176 MPTLLRVYIDGPHGMGKTTTTQLLVARDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE 4oqm B 2.20 BS01 FDU B 1 H58 E83 I97 Y101 Q125 M128 Y132 R163 A167 A168 Y172 E225 H13 E38 I52 Y56 Q80 M83 Y87 R113 A117 A118 Y122 E173 2.7.1.21 P03176 MPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE 4oqn B 2.30 BS01 EDU B 1 H58 E83 W88 I97 I100 Y101 Q125 M128 R163 A167 A168 Y172 E225 H13 E38 W43 I52 I55 Y56 Q80 M83 R113 A117 A118 Y122 E175 2.7.1.21 P03176 MPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE 4oqx A 2.50 BS01 EDV A 1 H58 W88 I97 I100 Y101 Q125 M128 R163 A167 A168 Y172 R222 H14 W42 I51 I54 Y55 Q79 M82 R112 A116 A117 Y121 R171 2.7.1.21 P03176 KMPTLLRVYIDGPHGMGKTTTTQLLVASRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE 4oqx B 2.50 BS01 EDV B 1 H58 W88 I97 Y101 Q125 M128 Y132 R163 A168 Y172 E225 H13 W43 I52 Y56 Q80 M83 Y87 R113 A118 Y122 E172 2.7.1.21 P03176 MPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE 4ou6 A 1.96 BS01 NUC L 1 F124 Y127 W128 K143 R146 S147 I150 G151 F41 Y44 W45 K60 R63 S64 I67 G68 P0A8J2 25053836 VPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLP 4ou6 B 1.96 BS01 NUC L 1 F124 Y127 W128 K143 S147 I150 F41 Y44 W45 K60 S64 I67 P0A8J2 25053836 VPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRAS 4ou6 C 1.96 BS01 NUC L 1 Y127 W128 Q142 K143 S147 I150 G151 Y44 W45 Q59 K60 S64 I67 G68 P0A8J2 25053836 VPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRA 4ou6 D 1.96 BS01 NUC L 1 Y127 W128 R146 S147 G151 Y44 W45 R63 S64 G68 P0A8J2 25053836 VPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRAS 4ou6 E 1.96 BS01 NUC L 1 Y127 W128 K143 S147 I150 Y44 W45 K60 S64 I67 P0A8J2 25053836 VPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRAS 4ou7 A 2.83 BS01 NUC S 1 Y127 W128 K143 R146 S147 I150 Y44 W45 K60 R63 S64 I67 P0A8J2 25053836 VPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRAS 4ou7 B 2.83 BS01 NUC S 1 Y127 K143 R146 S147 I150 Y44 K60 R63 S64 I67 P0A8J2 25053836 VPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRAS 4ou7 C 2.83 BS01 NUC S 1 Y127 W128 K143 R146 S147 I150 G151 Y44 W45 K60 R63 S64 I67 G68 P0A8J2 25053836 VPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRA 4ou7 D 2.83 BS01 NUC S 1 Y127 W128 K143 R146 I150 Y44 W45 K60 R63 I67 P0A8J2 25053836 VPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRAS 4oui A 2.17 BS02 CTO A 1 D40 H97 H101 N119 H124 Q125 P168 Y169 P193 W194 W229 D232 N237 W238 P271 N273 S274 L293 H295 F297 R304 D11 H68 H72 N90 H95 Q96 P139 Y140 P164 W165 W200 D203 N208 W209 P242 N244 S245 L264 H266 F268 R275 3.5.1.41 M7M1G8 24810719 PKGTIYLTFSDGPVNASVEVIKVLNQGGVKATFYFNAWHLDGIGDENEDRALEALKLALDSGHIVGNHSYDHMIHNCVEEFGPTSGADCNATGNHQIHSYQDPVRDAASFEQNLITLEKYLPTIRSYPNYKGYELARLPYTNGWRVTKHFQADGLCATSDNLKPWEPGYVCDPANPSNSVKASIQVQNILANQGYQTHGWDVDWAPENWGIPMPANSLTEAVPFLAYVDKALNSCSPTTIEPINSKTQEFPCGTPLHADKVIVLTHDFLFEDGKRGMGATQNLPKLAEFIRIAKEAGYVFDTMDNYTPRWSVGKTYQAGEYVLYQGVVYKAVISHTAQQDWAPSSTSSLWTNADPATNWTLNVSYEQGDIVNYKGKRYLVSVPHVSQQDWTPDTQNTLFTALE 4oui B 2.17 BS02 CTO B 1 D40 H97 H101 N119 H124 Q125 P168 Y169 P193 D232 W238 P271 N273 S274 L293 H295 R304 D11 H68 H72 N90 H95 Q96 P139 Y140 P164 D203 W209 P242 N244 S245 L264 H266 R275 3.5.1.41 M7M1G8 24810719 PKGTIYLTFSDGPVNASVEVIKVLNQGGVKATFYFNAWHLDGIGDENEDRALEALKLALDSGHIVGNHSYDHMIHNCVEEFGPTSGADCNATGNHQIHSYQDPVRDAASFEQNLITLEKYLPTIRSYPNYKGYELARLPYTNGWRVTKHFQADGLCATSDNLKPWEPGYVCDPANPSNSVKASIQVQNILANQGYQTHGWDVDWAPENWGIPMPANSLTEAVPFLAYVDKALNSCSPTTIEPINSKTQEFPCGTPLHADKVIVLTHDFLFEDGKRGMGATQNLPKLAEFIRIAKEAGYVFDTMDNYTPRWSVGKTYQAGEYVLYQGVVYKAVISHTAQQDWAPSSTSSLWTNADPATNWTLNVSYEQGDIVNYKGKRYLVSVPHVSQQDWTPDTQNTLFTALE 4oyf A 3.41 BS01 NA A 1 S278 G306 A307 N310 N401 D405 S261 G289 A290 N293 N384 D388 24842876 EYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE 4oze A 1.61 BS05 24G A 1 I18 H19 H58 E73 R137 Y151 G153 E154 F155 T179 F180 C181 E185 I186 K190 G195 G198 S199 V205 K227 R250 G251 G252 H253 I17 H18 H57 E72 R136 Y150 G152 E153 F154 T178 F179 C180 E184 I185 K189 G194 G197 S198 V204 K226 R249 G250 G251 H252 3.5.1.- O67648 GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFCFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ 4oze B 1.61 BS04 24G B 1 I18 H19 H58 E73 R137 Y151 G153 E154 F155 T179 F180 C181 E185 I186 G198 K227 R250 G251 G252 H253 I17 H18 H57 E72 R136 Y150 G152 E153 F154 T178 F179 C180 E184 I185 G197 K226 R249 G250 G251 H252 3.5.1.- O67648 GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFCFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK 4p10 A 2.00 BS01 2B8 A 1 H181 E184 N256 R257 H310 S311 Y312 S321 L362 A365 D370 E385 H157 E160 N232 R233 H286 S287 Y288 S297 L338 A341 D346 E361 3.4.17.20 Q96IY4 24588961 SGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTYGQGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNVLEP 4p4c A 1.60 BS01 25Q A 1 A651 K653 E670 M674 I683 I697 T699 E700 Y701 M702 L753 S763 A39 K41 E58 M62 I71 I85 T87 E88 Y89 M90 L141 S151 2.7.10.1 Q6P4R6 25076195 AKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITPSNLLLD 4p5f B 2.10 BS02 AR6 B 1 D116 K119 D120 P121 D122 D123 I232 M259 R277 A278 Y279 N280 K307 Y311 A341 L342 L345 L357 W361 F366 Y398 D399 D31 K34 D35 P36 D37 D38 I147 M174 R192 A193 Y194 N195 K222 Y226 A252 L253 L256 L268 W272 F277 Y293 D294 Q5GUA3 25079351 TPVLTPTEAAVLRELRLHRPQLPLDTLLFTDPNKDPDDVVTYTIAKQLQADGFLRLTDVVVTLGDADMRSQRAQLAKGVFDRLALPDVRVARGQDYPMTSTQAREHSKFLAEGAALRAAPDAVHTDGVRAMCERLATSPHKLGMVVIAGMTDASALLAEAGDLVREKVASITIMGGIDPARDADGLVQPDTRAYNNATDIHAARALYRRAQQLGIPLRILTKEAAYKAAVPPAFYEGGHPVGEYLRDVQKNALKGLWEGIQANLIPGLDTAWFFRTFVAFDAIWPQVTKLNLYDPLTLLAALPGTARLLFQPTPMSPVEHVGHAEVVRPEKARLLLSALAKAALV 4p5q A 1.35 BS01 Q0B A 1 G628 V635 A651 K653 M674 T699 E700 Y701 M702 E703 N704 G705 L753 S763 G20 V27 A43 K45 M66 T91 E92 Y93 M94 E95 N96 G97 L145 S155 2.7.10.1 P29320 25076195 VHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITPSNLLLD 4p5z A 2.00 BS01 Q7M A 1 A629 V635 A651 K653 E670 I673 M674 F677 I683 T699 E700 Y701 M702 L737 Y742 L753 V762 S763 D764 F765 A21 V27 A43 K45 E62 I65 M66 F69 I75 T91 E92 Y93 M94 L129 Y134 L145 V154 S155 D156 F157 2.7.10.1 P29320 25076195 VHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITNLLL 4pb1 A 2.80 BS01 RBV A 1 G153 E156 Y192 L259 N331 E332 F333 F366 N368 S371 I374 G152 E155 Y191 L247 N319 E320 F321 F354 N356 S359 I362 Q9KPL5 25082345 SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pb1 A 2.80 BS02 DMU A 1 L295 L369 A391 V395 L283 L357 A379 V383 Q9KPL5 25082345 SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pb2 A 2.30 BS01 5UD A 1 Q154 V188 L259 E332 F333 F366 N368 S371 I374 Q153 V187 L247 E320 F321 F354 N356 S359 I362 Q9KPL5 25082345 SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pb2 A 2.30 BS02 DMU A 1 L295 L369 I372 A391 V395 L283 L357 I360 A379 V383 Q9KPL5 25082345 SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pd5 A 2.91 BS01 GEO A 1 Q154 A185 Y192 L259 N331 E332 F333 F366 N368 S371 I374 Q152 A183 Y190 L246 N318 E319 F320 F353 N355 S358 I361 Q9KPL5 25082345 LFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pd5 A 2.91 BS02 DMU A 1 V329 L369 A391 V395 V316 L356 A378 V382 Q9KPL5 25082345 LFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pd6 A 2.08 BS02 DMU A 1 L369 A391 L354 A376 Q9KPL5 25082345 MSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pd7 A 2.91 BS01 ZE8 A 1 Q154 Y192 L259 N331 E332 F333 F366 N368 S371 I374 Q153 Y191 L247 N319 E320 F321 F354 N356 S359 I362 Q9KPL5 25082345 SLFMSLIGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pd7 A 2.91 BS02 DMU A 1 V329 L369 A391 V317 L357 A379 Q9KPL5 25082345 SLFMSLIGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pd8 A 2.75 BS01 P0C A 1 Q154 A185 V188 Y192 L259 E332 F333 F366 N368 S371 I374 Q153 A184 V187 Y191 L247 E320 F321 F354 N356 S359 I362 Q9KPL5 25082345 SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pd8 A 2.75 BS02 DMU A 1 V329 L369 I372 A391 V317 L357 I360 A379 Q9KPL5 25082345 SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pd9 A 3.10 BS01 ADN A 1 Q154 E156 A185 V188 Y192 N331 E332 F333 F366 N368 S371 I374 Q153 E155 A184 V187 Y191 N319 E320 F321 F354 N356 S359 I362 Q9KPL5 25082345 SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pd9 A 3.10 BS02 DMU A 1 I274 L295 L369 I372 A391 V395 I262 L283 L357 I360 A379 V383 Q9KPL5 25082345 SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4pda A 2.61 BS02 DMU A 1 V329 L369 I372 A391 V395 V317 L357 I360 A379 V383 Q9KPL5 25082345 SLFMSCCGMAVLLGIAVLLSSNRKAINLRTVGGAFAIQFSLGAFILYVPWGQELLRGFSDAVSNVINYGNDGTSFLFGGLVSGKMFEVFGGGGFIFAFRVLPTLIFFSALISVLYYLGVMQWVIRILGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASIAGGVLAGYASMGVKIEYLVAASFMAAPGGLLFAKLMMPETEKPQDKPANVIDAAAGGASAGLQLALNVGAMLIAFIGLIALINGMLGGIGGWFGMPELKLEMLLGWLFAPLAFLIGVPWNEATVAGEFIGLKTVANEFVAYSQFAPYLTEAAPVVLSEKTKAIISFALCGFANLSSIAILLGGLGSLAPKRRGDIARMGVKAVIAGTLSNLMAATIAGFFL 4phk A 2.05 BS01 2UB A 1 V127 H131 W168 K172 Q175 F226 V32 H36 W73 K77 Q80 F131 P04632 25086406 EEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 4phk B 2.05 BS01 2UB B 1 V127 H131 W168 K172 Q175 V32 H36 W73 K77 Q80 P04632 25086406 EEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 4phm A 2.03 BS01 2UD A 1 V127 L134 W168 K172 Q175 F226 V32 L39 W73 K77 Q80 F131 P04632 25086406 EEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 4phm A 2.03 BS03 CA A 2 D152 D154 T156 K158 G160 E163 D57 D59 T61 K63 G65 E68 P04632 25086406 EEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 4phm B 2.03 BS01 2UD B 1 V127 W168 K172 Q175 F226 V32 W73 K77 Q80 F131 P04632 25086406 EEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 4pk2 A 1.35 BS01 III B 1 Q58 I64 K102 I121 L122 D123 D157 R158 N182 F183 Q50 I56 K94 I113 L114 D115 D149 R150 N174 F175 2.3.1.108 Q5SQI0 24906155 FTMEFPFDVDALFPERITVLDQHLRPPAVDLQQQIMTIIDELGKASAKAQNLSAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHPP 4pk2 A 1.35 BS02 COA B 1 Q58 F124 Y125 I126 Q131 R132 H133 G134 G136 R137 P159 S160 K162 L163 K165 F166 K169 H170 Q50 F116 Y117 I118 Q123 R124 H125 G126 G128 R129 P151 S152 K154 L155 K157 F158 K161 H162 2.3.1.108 Q5SQI0 24906155 FTMEFPFDVDALFPERITVLDQHLRPPAVDLQQQIMTIIDELGKASAKAQNLSAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHPP 4pk3 A 1.35 BS01 III B 1 Q58 L60 I64 K102 L122 D123 F124 I156 D157 R158 P159 L163 N181 N182 F183 Q50 L52 I56 K94 L114 D115 F116 I148 D149 R150 P151 L155 N173 N174 F175 2.3.1.108 Q5SQI0 24906155 FTMEFPFDVDALFPERITVLDQHLRPPAVDLQQQIMTIIDELGKASAKAQNLSAPITSASRMQSNRHVVYILKDSSARPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHPP 4q85 A 3.29 BS01 APC A 1 K61 A70 S71 G74 E75 E78 S184 A185 G186 N187 Q195 E199 R203 R286 E290 K50 A59 S60 G63 E64 E67 S173 A174 G175 N176 Q184 E188 R192 R275 E279 P75838 ALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q85 A 3.29 BS02 MG A 1 S215 L216 Y247 L334 F335 K336 S204 L205 Y236 L312 F313 K314 P75838 ALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q85 A 3.29 BS03 MG A 2 E78 M183 E199 E67 M172 E188 P75838 ALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q85 A 3.29 BS04 MG A 3 K61 E202 R203 R286 E290 K50 E191 R192 R275 E279 P75838 ALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q85 B 3.29 BS01 APC B 1 K9 S16 K61 A70 S71 G74 E75 E78 S184 A185 N187 E191 Q195 E199 R203 R286 E290 K8 S15 K60 A69 S70 G73 E74 E77 S183 A184 N186 E190 Q194 E198 R202 R285 E289 P75838 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAFW 4q85 C 3.29 BS02 MG C 2 E78 E199 E65 E186 P75838 EDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q85 D 3.29 BS03 MG D 2 K61 E202 R203 E290 K60 E201 R202 E289 P75838 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAF 4q85 D 3.29 BS04 MG D 3 E78 M183 Q195 E199 E77 M182 Q194 E198 P75838 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAF 4q85 G 3.29 BS01 MG G 1 S215 L216 Y247 L334 K336 S191 L192 Y223 L298 K300 P75838 SDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q85 H 3.29 BS03 MG H 2 E75 E78 E199 E74 E77 E198 P75838 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAFW 4q85 H 3.29 BS05 MG H 4 V445 R446 W459 L462 V434 R435 W448 L451 P75838 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAFW 4q86 A 2.25 BS01 AMP A 1 K9 F20 K61 A70 S71 G74 E75 E78 S184 A185 G186 Q195 R286 K8 F19 K60 A69 S70 G73 E74 E77 S183 A184 G185 Q194 R285 P75838 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAF 4q86 B 2.25 BS01 AMP B 1 K9 L13 S16 F20 K61 A70 S71 G74 E75 E78 S184 A185 N187 E191 Q195 R286 K8 L12 S15 F19 K60 A69 S70 G73 E74 E77 S183 A184 N186 E190 Q194 R285 P75838 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAFW 4q86 C 2.25 BS01 AMP C 1 L13 F20 K61 A70 S71 G74 E75 E78 S184 A185 N187 E191 Q195 R286 L2 F9 K50 A59 S60 G63 E64 E67 S173 A174 N176 E180 Q184 R275 P75838 ALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4q86 D 2.25 BS01 AMP D 1 K9 K61 A70 S71 G74 E75 E78 S184 A185 G186 N187 Q195 R286 K8 K60 A69 S70 G73 E74 E77 S183 A184 G185 N186 Q194 R285 P75838 TQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAF 4q86 E 2.25 BS01 AMP E 1 K9 K61 S71 G74 E75 E78 S184 A185 G186 E191 Q195 R286 K6 K58 S68 G71 E72 E75 S181 A182 G183 E188 Q192 R283 P75838 TFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKA 4qlw D 2.00 BS01 FE D 1 G45 H46 C112 F114 H117 E121 G45 H46 C112 F114 H117 E121 P00282 25082811 AECSVDIQGNDQMQFNTNAITVDKSCKQFTVNLSHPGNLPKNVMGHNWVLSTAADMQGVVTDGMASGLDKDYLKPDDSRVIAHTKLIGSGEKDSVTFDVSKLKEGEQYMFFCTFPGHSALEKGTLTLK 4qn1 A 2.48 BS01 ZN A 1 C1229 H1230 C1241 C1244 C221 H222 C233 C236 Q149N8 GTMEELLTSLQKKCGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSMSEKFRDCRGLQFLLTTQMEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSNTLWAISETERSMKAILSFAKSHRFDVEFVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPLHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEK 4qpw A 1.14 BS01 XYP A 1 H210 Q213 Q282 H52 Q55 Q124 B3CET4 VDKVDYEIDYSTAGYSFWNEVNEEVKETTTIGKNDTEGCLEIKTSVAASQNHFIQYHTADNLPIEIGKEYKLKMMVRGSAEGKLNFGVGPWSGRAEGSFSFNTEWKEYEFSFKAVADGGHVMTQSGLFVGTIQIKYVKITHS 4qpw A 1.14 BS02 XYP A 2 W176 E178 W249 W18 E20 W91 B3CET4 VDKVDYEIDYSTAGYSFWNEVNEEVKETTTIGKNDTEGCLEIKTSVAASQNHFIQYHTADNLPIEIGKEYKLKMMVRGSAEGKLNFGVGPWSGRAEGSFSFNTEWKEYEFSFKAVADGGHVMTQSGLFVGTIQIKYVKITHS 4qse A 1.37 BS01 GOL A 1 D89 N142 E195 F199 W265 G297 D298 R367 D62 N115 E168 F172 W238 G270 D271 R340 A9CGI0 DVTLTLWSLDRDIQPAPNLIKEFNALNNGIKIEYRQLQFDDVVSESMRAYSTGNAPDIIAIDNPNHAMFASRGAFLDVTDMIAKSDVIKTENYFPGPLKSVTWDGKYFGVPKATNTIALYYNKDLFKAAGLDAAKPPQTWDELVDAARKLTNPAKNVYGISFSAKANEEGTFQFLPWAQMAGATYKNINTDGAVKALETWKTLLDEKLASPDTLTRSQWDSTATFNAGNAAMAISGPWEIDRMLKDAKFDWGVTLLPVPTPDAPRSSAMGDYNWAIFSKTKHPAEAFKAIEFFASKDKDMFKNFGQLPARSDIPVPPTGNALKDEALKTFVEQLKYAQPRGPSPEWPKISKAIQDAIQGALSGQMTPKAALDQAAEKIKLVD 4qse A 1.37 BS02 GOL A 2 K150 D277 W278 L349 K123 D250 W251 L322 A9CGI0 DVTLTLWSLDRDIQPAPNLIKEFNALNNGIKIEYRQLQFDDVVSESMRAYSTGNAPDIIAIDNPNHAMFASRGAFLDVTDMIAKSDVIKTENYFPGPLKSVTWDGKYFGVPKATNTIALYYNKDLFKAAGLDAAKPPQTWDELVDAARKLTNPAKNVYGISFSAKANEEGTFQFLPWAQMAGATYKNINTDGAVKALETWKTLLDEKLASPDTLTRSQWDSTATFNAGNAAMAISGPWEIDRMLKDAKFDWGVTLLPVPTPDAPRSSAMGDYNWAIFSKTKHPAEAFKAIEFFASKDKDMFKNFGQLPARSDIPVPPTGNALKDEALKTFVEQLKYAQPRGPSPEWPKISKAIQDAIQGALSGQMTPKAALDQAAEKIKLVD 4qtj A 2.10 BS01 NUC B 1 R38 I63 K64 R65 T67 R76 R34 I59 K60 R61 T63 R72 Q5AP80 MIVPTYNGYIHNTRDALAVIQQVLDKQLEPVSRRPHERERGVLIVSGSVFVFIEQSSGIKRWTDGISWSPSRIQGRFLVYGELDKKGLVKKTITLTTTTKELHMEGKAEKQTIHLISYYSKQDIDSGKLQRPSESDLKHVQISPALWTMVQENS 4qtj A 2.10 BS02 NUC C 1 R65 W66 S75 L82 Y84 K206 T210 R61 W62 S71 L78 Y80 K90 T94 Q5AP80 MIVPTYNGYIHNTRDALAVIQQVLDKQLEPVSRRPHERERGVLIVSGSVFVFIEQSSGIKRWTDGISWSPSRIQGRFLVYGELDKKGLVKKTITLTTTTKELHMEGKAEKQTIHLISYYSKQDIDSGKLQRPSESDLKHVQISPALWTMVQENS 4qtk A 2.99 BS01 NUC C 1 R38 K64 R65 T67 R76 R33 K59 R60 T62 R71 Q5AP80 IVPTYNGYIHNTRDALAVIQQVLDKQLEPVSRRPHERERGVLIVSGSVFVFIEQSSGIKRWTDGISWSPSRIQGRFLVYGEGLVKKTITLTTTTKELHMEGKAEKQTIHLISYYSKQDIDSGKLQRPSESDLKHVQISPALWTMV 4qtk A 2.99 BS02 NUC D 1 R65 W66 W72 S75 L82 Y84 K206 T210 R60 W61 W67 S70 L77 Y79 K85 T89 Q5AP80 IVPTYNGYIHNTRDALAVIQQVLDKQLEPVSRRPHERERGVLIVSGSVFVFIEQSSGIKRWTDGISWSPSRIQGRFLVYGEGLVKKTITLTTTTKELHMEGKAEKQTIHLISYYSKQDIDSGKLQRPSESDLKHVQISPALWTMV 4qtk B 2.99 BS02 NUC F 1 R65 W66 W72 S75 L82 Y84 K206 T208 T210 R60 W61 W67 S70 L77 Y79 K87 T89 T91 Q5AP80 IVPTYNGYIHNTRDALAVIQQVLDKQLEPVSRRPHERERGVLIVSGSVFVFIEQSSGIKRWTDGISWSPSRIQGRFLVYGELNGLVKKTITLTTTTKELHMEGKAEKQTIHLISYYSKQDIDSGKLQRPSESDLKHVQISPALWTMVQ 4qu6 A 1.75 BS01 NUC B 1 Q155 G156 L157 P158 W159 G194 R220 Y221 E223 Q9 G10 L11 P12 W13 G48 R74 Y75 E77 Q12849 DDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSP 4qu6 A 1.75 BS02 CA A 1 D147 V149 D233 D1 V3 D87 Q12849 DDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSP 4qu7 A 2.50 BS01 NUC U 1 R406 G407 L408 P409 F410 T440 R467 Y468 E470 R7 G8 L9 P10 F11 T41 R68 Y69 E71 Q12849 MHFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLNSCPKGK 4qu7 B 2.50 BS01 NUC V 1 R406 G407 L408 P409 F410 R467 Y468 E470 R7 G8 L9 P10 F11 R68 Y69 E71 Q12849 MHFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELFLNSCPK 4qym A 1.58 BS01 MET A 1 L70 Q74 T130 L131 S132 S153 N154 T155 F204 D280 F331 L18 Q22 T78 L79 S80 S101 N102 T103 F152 D228 F279 Q3MFZ5 NTIPIGIALAQTSNVALLGQEQVAGAKIAEKYFNDKGGVNGTPIKLIFQDTAGDEAGTINAFQTLINKDKVVGIVGPTLSQQAFSANPIAERAKVPVVGPSNTAKGIPEIGDYVARVSAPVSVVAPNSVKAALKQNPNIKKVAVFFAQNDAFSKSETEIFQQTVKDQGLELVTVQKFQTTDTDFQSQATNAINLKPDLVIISGLAADGGNLVRQLRELGYQGAIIGGDGLNTSNVFAVCKALCDGVLIAQAYSPEYTGEINKAFRQAYVDQYKKEPPQFSAQAFAAVQVYVESLKALDTKNKVSKIQLPELRTELNKQLLTGKYNTPLGEISFTPIGEVVQKDFYVAQIKMEKDGSQGKFTFLK 4r02 J 2.50 BS01 MG J 1 Q118 T124 Q118 T124 3.4.25.1 P22141 25087721 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDF 4r02 L 2.50 BS01 3E5 K 1 Y106 D126 P127 S130 Y106 D126 P127 S130 3.4.25.1 P23724 25087721 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 4r02 Y 2.50 BS01 3E5 Y 1 T1 A20 T21 M45 G47 A49 T1 A20 T21 M45 G47 A49 3.4.25.1 P30656 25087721 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4tnw A 3.20 BS01 POV A 1 Q219 P223 M226 L227 T255 Q259 G262 Q219 P223 M226 L227 T255 Q259 G262 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGHHH 4tnw D 3.20 BS01 POV D 1 S260 N264 I280 G281 M284 T285 F288 S260 N264 I280 G281 M284 T285 F288 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw E 3.20 BS01 POV A 1 S260 N264 I280 G281 M284 S260 N264 I280 G281 M284 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw E 3.20 BS02 POV D 1 Q219 P223 Q259 Q219 P223 Q259 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw P 3.20 BS01 POV P 1 L218 Q219 P223 M226 L227 V230 Q259 L218 Q219 P223 M226 L227 V230 Q259 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw P 3.20 BS02 POV Q 1 T257 S260 A261 N264 G281 A282 M284 T285 F286 F288 C289 L326 T257 S260 A261 N264 G281 A282 M284 T285 F286 F288 C289 L326 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw Q 3.20 BS01 POV Q 1 L218 Q219 P223 M226 V230 A258 Q259 G262 L218 Q219 P223 M226 V230 A258 Q259 G262 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw Q 3.20 BS02 POV R 1 S260 N264 I280 G281 M284 T285 L292 S260 N264 I280 G281 M284 T285 L292 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw R 3.20 BS01 POV R 1 L218 Q219 M226 L227 V230 T255 Q259 G262 L218 Q219 M226 L227 V230 T255 Q259 G262 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw R 3.20 BS02 POV R 2 G281 A282 M284 F286 F288 C289 L292 G281 A282 M284 F286 F288 C289 L292 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw S 3.20 BS01 POV R 3 P223 M226 L227 V230 T255 Q259 P223 M226 L227 V230 T255 Q259 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw S 3.20 BS02 POV T 1 S260 N264 I280 G281 A282 M284 T285 F286 F288 C289 L292 S260 N264 I280 G281 A282 M284 T285 F286 F288 C289 L292 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw T 3.20 BS01 POV P 1 S260 N264 V278 I280 G281 M284 T285 F286 F288 C289 S260 N264 V278 I280 G281 M284 T285 F286 F288 C289 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tnw T 3.20 BS02 POV T 1 L218 Q219 P223 M226 L227 V230 Q259 G262 L218 Q219 P223 M226 L227 V230 Q259 G262 G5EBR3 SDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANAGTTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGH 4tpw A 1.50 BS01 MGP A 1 W56 Q57 M101 W102 E103 R157 K162 W166 K206 G208 W24 Q25 M69 W70 E71 R125 K130 W134 K174 G176 P06730 25049413 HYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 4tpw A 1.50 BS02 33R A 1 F47 K49 N59 R61 I63 H78 I79 S83 Y91 F15 K17 N27 R29 I31 H46 I47 S51 Y59 P06730 25049413 HYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 4tqb A 1.59 BS01 MGT A 1 W56 M101 W102 E103 R157 K162 W166 K206 G208 W24 M69 W70 E71 R125 K130 W134 K174 G176 P06730 25049413 HYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 4tqb A 1.59 BS02 34K A 1 F47 K49 N59 R61 I63 L75 H78 I79 F15 K17 N27 R29 I31 L43 H46 I47 P06730 25049413 HYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 4tqc A 1.80 BS02 34J A 1 F47 K49 N59 R61 H78 S82 F13 K15 N25 R27 H44 S48 P06730 25049413 IKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSKNRFVV 4tqc B 1.80 BS01 M7G B 1 W56 Q57 M101 W102 E103 R157 K162 W166 W22 Q23 M67 W68 E69 R123 K128 W132 P06730 25049413 IKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSKNRFVV 4trj A 1.73 BS02 665 A 1 G96 F97 M103 G104 F149 P156 A157 Y158 M199 I215 L218 G95 F96 M102 G103 F148 P155 A156 Y157 M198 I214 L217 1.3.1.9 P9WGR0 17034137 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4tvx F 3.24 BS01 NUC L 1 N19 R20 D21 D22 N24 K27 S40 Q42 S43 K45 R46 R49 G164 M166 K177 D179 F200 T201 A202 V203 Q209 G210 S211 A265 K266 T269 N18 R19 D20 D21 N23 K26 S39 Q41 S42 K44 R45 R48 G160 M162 K173 D175 F196 T197 A198 V199 Q205 G206 S207 A261 K262 T265 Q46899 SNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVDKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPQVKQMPTLEQLKSWVRNNGEA 4tvx D 3.24 BS01 NUC L 1 N19 R20 D21 D22 N24 K27 S40 Q42 S43 K45 R46 R49 R64 S163 G164 M166 F200 T201 A202 V203 A212 G264 A265 K266 N18 R19 D20 D21 N23 K26 S39 Q41 S42 K44 R45 R48 R63 S160 G161 M163 F197 T198 A199 V200 A206 G258 A259 K260 Q46899 SNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVDEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLKSWVRNNGE 4tvx E 3.24 BS01 NUC L 1 N19 R20 D21 D22 K27 S40 Q42 S43 K45 R46 R49 R64 G164 M166 W199 F200 T201 A202 V203 H213 A265 K266 N18 R19 D20 D21 K26 S39 Q41 S42 K44 R45 R48 R63 G159 M161 W194 F195 T196 A197 V198 H204 A256 K257 Q46899 SNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDAQVKQMPTLEQLKSWVRNNGEA 4tvx C 3.24 BS01 NUC L 1 N19 R20 D21 D22 K27 S40 Q42 S43 K45 R46 R49 R64 G164 M166 W199 F200 T201 A202 V203 A212 L214 A265 K266 T269 N18 R19 D20 D21 K26 S39 Q41 S42 K44 R45 R48 R63 G158 M160 W193 F194 T195 A196 V197 A203 L205 A256 K257 T260 Q46899 SNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDQVKQMPTLEQLKSWVRNNGE 4tvx G 3.24 BS01 NUC L 1 N19 R20 D21 D22 K27 S40 Q42 S43 K45 R46 R49 S163 G164 R165 M166 A167 K177 V178 D179 W199 F200 T201 A202 V203 Q234 A265 K266 R268 N18 R19 D20 D21 K26 S39 Q41 S42 K44 R45 R48 S156 G157 R158 M159 A160 K170 V171 D172 W192 F193 T194 A195 V196 Q227 A258 K259 R261 Q46899 SNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPIQVKQMPTLEQLKSWVRNNGE 4tvx H 3.24 BS01 NUC L 1 W16 G17 Q18 P19 T20 R25 P26 S34 G35 G38 L39 G41 A42 I46 R48 L54 Y85 H86 T87 V88 L89 R108 Y142 P144 Y145 G147 R148 R149 R197 R206 F208 W16 G17 Q18 P19 T20 R25 P26 S34 G35 G38 L39 G41 A42 I46 R48 L54 Y85 H86 T87 V88 L89 R108 Y142 P144 Y145 G147 R148 R149 R197 R206 F208 Q46898 MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGG 4tvx U 3.24 BS01 NUC X 1 F129 V130 Q132 F127 V128 Q130 Q46901 LLIDNWIPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALALLVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGGGFKSGLRGGTPVTTFVRGIDLRSTVLLNVLTLPRLQKQFPNESHTENQPTWIKPIKSNESIPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNNGNRVAAVVNQFRNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANVNFSQADEVIADLRDKLHQLCEMLFNQSVAPYAHHPKLISTLALARATLYKHLRELKPQ 4tvx U 3.24 BS02 ZN U 1 C140 C143 C250 C252 C253 C138 C141 C248 C250 C251 Q46901 LLIDNWIPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALALLVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGGGFKSGLRGGTPVTTFVRGIDLRSTVLLNVLTLPRLQKQFPNESHTENQPTWIKPIKSNESIPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNNGNRVAAVVNQFRNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANVNFSQADEVIADLRDKLHQLCEMLFNQSVAPYAHHPKLISTLALARATLYKHLRELKPQ 4tvx I 3.24 BS01 ZN I 1 C140 C143 C250 C253 C138 C141 C248 C251 Q46901 LLIDNWIPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALALLVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGGGFKSGLRGGTPVTTFVRGIDLRSTVLLNVLTLPRLQKQFPNESHTENQPTWIKPIKSNESIPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNNGNRVAAVVNQFRNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANVNFSQADEVIADLRDKLHQLCEMLFNQSVAPYAHHPKLISTLALARATLYKHLRELKPQ 4txy A 3.00 BS01 MG A 1 D132 D134 D194 D128 D130 D184 2.7.7.86 Q9KVG7 TWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAKGIAKAVKKSALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDEFLGLTPRFWTQGSFQYDTLNRPFQPGQEMDIDDGTYMPMPIIGHSLLILLVDASLKSLVAENHGWKFEAKQTCGRIKIEAEKTHIDVPMYAIPKDEFQKKQIAELDSENVNLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWDVGGPSSISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPDSTDEKPLFPPSYKHGPREMDIMSKLERLPEILSSAESADSKSEALKKINMAFGNRVTNSELIVLAKA 4txz A 2.80 BS02 MG A 2 G114 S115 D132 D134 G110 S111 D128 D130 2.7.7.86 Q9KVG7 TWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAKGIAKAVKKSALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDEFLGLTPRFWTQGSFQYDTLNRPFQPGQEMDIDDGTYMPMPIKIGHSLLILLVDASLKSLVAENHGWKFEAKQTCGRIKIEAEKTHIDVPMYAIPKDEFELDSENVNLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWDVGGPSSISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPDSTDEKPLFPPSYKHGPREMDIMSKLERLPEILSSAESADSKSEALKKINMAFGNRVTNSELIVLAKA 4txz A 2.80 BS03 G2P A 1 Q113 G114 S115 Y118 D132 D134 P262 K288 S302 D346 D349 L353 Q109 G110 S111 Y114 D128 D130 P219 K245 S259 D303 D306 L310 2.7.7.86 Q9KVG7 TWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAKGIAKAVKKSALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDEFLGLTPRFWTQGSFQYDTLNRPFQPGQEMDIDDGTYMPMPIKIGHSLLILLVDASLKSLVAENHGWKFEAKQTCGRIKIEAEKTHIDVPMYAIPKDEFELDSENVNLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWDVGGPSSISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPDSTDEKPLFPPSYKHGPREMDIMSKLERLPEILSSAESADSKSEALKKINMAFGNRVTNSELIVLAKA 4txz B 2.80 BS02 MG B 2 S115 D132 D134 S111 D128 D130 2.7.7.86 Q9KVG7 TWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAKGIAKAVKKSALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDEFLGLTPRFWTQGSFQYDTLNRPFQPGQEMDIDDGTYMPMPIGHSLLILLVDASLKSLVAENHGWKFEAKQTCGRIKIEAEKTHIDVPMYAIPKDEFDSENVNLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWDVGGPSSISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPDSTDEKPLFPPSYKHGPREMDIMSKLERLPEILSSAESADSKSEALKKINMAFGNRVTNSELIVLAKA 4ty0 A 1.80 BS02 MG A 2 D132 D134 D130 D132 2.7.7.86 Q9KVG7 SMTWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAKGIAKAVKKSALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDEFLGLTPRFWTQGSFQYDTLNRPFQPGQEMDIDDGTYMPMPIIGHSLLILLVDASLKSLVAENHGWKFEAKQTCGRIKIEAEKTHIDVPMYAIPKDEFQKKQIALEANRSYELDSENVNLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWDVGGPSSISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPDSTDEKPLFPPSYKHGPREMDIMSKLERLPEILSSAESADSKSEALKKINMAFGNRVTNSELIVLAKA 4ty0 A 1.80 BS03 38V A 1 Q113 G114 S115 Y118 D132 D134 K178 T180 C181 D194 Y198 S260 P262 V265 K288 S302 L353 Q111 G112 S113 Y116 D130 D132 K170 T172 C173 D186 Y190 S231 P233 V236 K259 S273 L324 2.7.7.86 Q9KVG7 SMTWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAKGIAKAVKKSALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDEFLGLTPRFWTQGSFQYDTLNRPFQPGQEMDIDDGTYMPMPIIGHSLLILLVDASLKSLVAENHGWKFEAKQTCGRIKIEAEKTHIDVPMYAIPKDEFQKKQIALEANRSYELDSENVNLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWDVGGPSSISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPDSTDEKPLFPPSYKHGPREMDIMSKLERLPEILSSAESADSKSEALKKINMAFGNRVTNSELIVLAKA 4ty0 B 1.80 BS03 38V B 1 Q113 G114 S115 Y118 D132 D134 K178 T180 C181 D194 P196 Y198 L248 S260 P262 K288 S302 L353 Q109 G110 S111 Y114 D128 D130 K166 T168 C169 D182 P184 Y186 L199 S211 P213 K239 S253 L304 2.7.7.86 Q9KVG7 TWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAKGIAKAVKKSALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDEFLGLTPRFWTQGSFQYDTLNRPFQPGQEMDIDDGTYMPMPGHSLLILLVDASLKSLVAENHGWKFEAKQTCGRIKIEAEKTHIDVPMYAIPKDEFSENVNLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWDVGGPSSISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPDSTDEKPLFPPSYKHGPREMDIMSKLERLPEILSSAESADSKSEALKKINMAFGNRVTNSELIVLA 4tyx A 1.64 BS01 HEM A 1 T39 K42 H43 R45 H64 T67 V68 A71 L89 A92 H93 H97 I99 Y103 L104 I107 T39 K42 H43 R45 H64 T67 V68 A71 L89 A92 H93 H97 I99 Y103 L104 I107 P02185 25076049 VLSEGEWQLVLHVWAKVEADVAGHGQDIHIRLYKSHPETLEKHDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQAHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG 4u5b A 3.50 BS01 FWF D 1 I481 P494 M496 S497 S729 K730 L751 S754 I468 P481 M483 S484 S662 K663 L684 S687 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTEEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSARIVAGVWWFFTLIIISSYTANLATFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGASALSLSNVAGVFYILVGGLGLAMLVALIEF 4u5b B 3.50 BS01 FWF B 1 I481 K493 P494 M496 S497 S729 K730 L751 S754 I472 K484 P485 M487 S488 S666 K667 L688 S691 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTESGDLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSARIVAGVWWFFTLIIISSYTANLATFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGKTSALSLSNVAGVFYILVGGLGLAMLVALIEF 4u5b C 3.50 BS01 FWF B 1 I481 K493 P494 M496 S497 S729 K730 S754 I467 K479 P480 M482 S483 S661 K662 S686 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSARIVAGVWWFFTLIIISSYTANLATFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEF 4u5b D 3.50 BS01 FWF D 1 I481 P494 M496 S497 S729 K730 G731 L751 S754 I468 P481 M483 S484 S662 K663 G664 L684 S687 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSARIVAGVWWFFTLIIISSYTANLATFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGTSALSLSNVAGVFYILVGGLGLAMLVALIEF 4u5c A 3.69 BS01 FWD A 1 E402 Y450 P478 L479 T480 R485 G653 S654 T655 T686 L704 E705 M708 E389 Y437 P465 L466 T467 R472 G593 S594 T595 T626 L644 E645 M648 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNIDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTESGDGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLVSSPRSLSARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGSALSLSNVAGVFYILVGGLGLAMLVALIEFAYK 4u5c A 3.69 BS02 FWF D 1 I481 K493 P494 M496 S497 S729 K730 G731 S754 I468 K480 P481 M483 S484 S669 K670 G671 S694 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNIDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTESGDGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLVSSPRSLSARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGSALSLSNVAGVFYILVGGLGLAMLVALIEFAYK 4u5c B 3.69 BS01 FWD B 1 Y450 P478 L479 T480 R485 G653 S654 T655 T686 E705 M708 Y440 P468 L469 T470 R475 G594 S595 T596 T627 E646 M649 P19491 SIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTESGGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSPRSLSARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGSLSNVAGVFYILVGGLGLAMLVALIEFAYKR 4u5c B 3.69 BS02 FWF B 1 I481 K493 P494 M496 S497 S729 K730 G731 L751 S754 I471 K483 P484 M486 S487 S670 K671 G672 L692 S695 P19491 SIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTESGGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSPRSLSARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGSLSNVAGVFYILVGGLGLAMLVALIEFAYKR 4u5c D 3.69 BS02 FWF D 1 I481 P494 M496 S497 S729 K730 G731 S754 I470 P483 M485 S486 S675 K676 G677 S700 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLVSRADISPRSLSARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSALSLSNVAGVFYILVGGLGLAMLVALIEF 4u5d A 3.58 BS01 FWF A 1 K493 P494 M496 S497 S729 K730 L751 S754 K480 P481 M483 S484 S662 K663 L684 S687 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTEEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGASLSNVAGVFYILVGGLGLAMLVALIEF 4u5d C 3.58 BS01 FWF B 1 I481 K493 P494 M496 S497 S729 L751 S754 I468 K480 P481 M483 S484 S662 L684 S687 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEF 4u5d D 3.58 BS01 FWF A 1 P494 F495 M496 S497 S729 K730 S754 P484 F485 M486 S487 S665 K666 S690 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTTSGLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGKTSALSLSNVAGVFYILVGGLGLAMLVALIEF 4u5e A 3.51 BS01 FWF A 1 I481 K493 P494 F495 M496 S497 S729 K730 V750 L751 S754 I468 K480 P481 F482 M483 S484 S662 K663 V683 L684 S687 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTEEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSARIVAGVWWFFTLIIISSYTANLAAFLGVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGASALSLSNVAGVFYILVGGLGLAMLVALIEF 4u5e D 3.51 BS01 FWF A 1 I481 P494 M496 S497 S729 K730 S754 I468 P481 M483 S484 S662 K663 S687 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKGERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTLEQKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWDGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSVVLFLSARIVAGVWWFFTLIIISSYTANLAAFLGVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGTSALSLSNVAGVFYILVGGLGLAMLVALIEF 4u5g A 2.20 BS01 ZN A 1 D15 E19 D12 E16 P0CB20 ADCCRMKECCTDRVNECLQRYSGREDKFVSFCYQEATVTCGSFNEIVGCCYGYQMCMIRVVKPNSLSGAHEACKTVSCGNPCA 4u5g A 2.20 BS02 ZN A 2 H73 E74 H70 E71 P0CB20 ADCCRMKECCTDRVNECLQRYSGREDKFVSFCYQEATVTCGSFNEIVGCCYGYQMCMIRVVKPNSLSGAHEACKTVSCGNPCA 4u65 E 2.10 BS01 CA E 1 D111 Y120 D134 E136 D137 D61 Y70 D84 E86 D87 Q3KK32 ADWDFSAISRKATALYGPLGAGQQRIDAWQNLLATQKQVSEMEKLKVVNLFFNKQMRYVEDIDLWHEVDYWETPIEALWKGAGDCEDYAIAKYFSLRHLGVASDKLRITYVKALRQNRAHMVLTYYSSPDAMPLVLDSLIDPIKPAAERTDLLPVYSFNAEGLLSRWQDVLKKMQAEGFPV 4u65 E 2.10 BS02 CA E 2 D111 D119 D134 E136 D61 D69 D84 E86 Q3KK32 ADWDFSAISRKATALYGPLGAGQQRIDAWQNLLATQKQVSEMEKLKVVNLFFNKQMRYVEDIDLWHEVDYWETPIEALWKGAGDCEDYAIAKYFSLRHLGVASDKLRITYVKALRQNRAHMVLTYYSSPDAMPLVLDSLIDPIKPAAERTDLLPVYSFNAEGLLSRWQDVLKKMQAEGFPV 4umv A 3.20 BS01 MG A 1 D436 T438 D628 G629 D311 T313 D503 G504 3.6.3.5 Q3YW59 KENLPLITLIVMMAISWGLEQFNHPFGQLAFIATTLVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEGWAASRARQGVSALMALKPETATRLRNGEREEVAINSLRPGDVIEVAAGGRLPADGKLLSPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIEEAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGCPCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTAIHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEAQVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGIIALQDTLRADAATAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTKLNQHAPLAMVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANIRQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLR 4umv A 3.20 BS02 BEF A 1 G289 D436 T438 T583 K610 D628 N631 G164 D311 T313 T458 K485 D503 N506 3.6.3.5 Q3YW59 KENLPLITLIVMMAISWGLEQFNHPFGQLAFIATTLVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEGWAASRARQGVSALMALKPETATRLRNGEREEVAINSLRPGDVIEVAAGGRLPADGKLLSPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIEEAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGCPCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTAIHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEAQVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGIIALQDTLRADAATAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTKLNQHAPLAMVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANIRQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLR 4umw A 2.70 BS01 ALF A 1 T288 G289 D436 K437 T438 T583 G584 K610 N631 T161 G162 D309 K310 T311 T456 G457 K483 N504 3.6.3.5 Q3YW59 RLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATTLVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEGWAASRVSALMALKPETATRLRNGEREEVAINSLRPGDVIEVAAGGRLPADGKLLSPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIEEAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGCPCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTAIHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEAQVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGIIALQDTLRADAATAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTKLNQHAPLAMVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANIRQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLR 4umw A 2.70 BS02 MG A 1 D436 T438 D628 G629 D632 D309 T311 D501 G502 D505 3.6.3.5 Q3YW59 RLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATTLVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEGWAASRVSALMALKPETATRLRNGEREEVAINSLRPGDVIEVAAGGRLPADGKLLSPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIEEAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGCPCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTAIHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEAQVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGIIALQDTLRADAATAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTKLNQHAPLAMVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANIRQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLR 4uq6 A 12.80 BS01 GLU A 1 Y450 P478 L479 T480 R485 L650 G653 S654 T655 E705 Y732 Y433 P461 L462 T463 R468 L508 G511 S512 T513 E563 Y590 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNPVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4uq6 C 12.80 BS01 GLU C 1 Y450 P478 T480 R485 L650 G653 S654 T655 E705 Y433 P461 T463 R468 L508 G511 S512 T513 E563 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNPVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4uqj D 10.40 BS01 ZK1 D 1 E402 Y450 P478 L479 T480 R485 G653 S654 T686 E705 T707 Y732 E385 Y433 P461 L462 T463 R468 G597 S598 T630 E649 T651 Y676 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTLKTVVVTTILESPYVMMKKNHEMLKGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSTNEFGIFNSLWFSLGAFMQPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGLLDKLKNKWWYDKGECSNVAGVFYILVGGLGLAMLVALIEFCYK 4uqk A 16.40 BS01 QUS A 1 Y450 P478 L479 T480 R485 L650 G653 S654 T655 L704 E705 M708 Y433 P461 L462 T463 R468 L508 G511 S512 T513 L562 E563 M566 P19491 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVLTEKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4uqq A 7.60 BS01 GLU A 1 Y457 P485 L486 A487 R492 G657 A658 T659 E707 Y442 P470 L471 A472 R477 G564 A565 T566 E614 P42260 THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTENRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKGVFSFLNPLSPDIWMYVLLACWFFTLIIISSYTANLAAFLTVERPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEQNIGGIFIVLA 4uuu A 1.71 BS01 SAM A 1 P422 L423 G442 F443 D444 Q445 A446 T535 I537 D538 P24 L25 G44 F45 D46 Q47 A48 T127 I129 D130 4.2.1.22 P35520 NLYFQSMKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQQRQMVFGVVTAIDLLNFVAA 4uuu A 1.71 BS02 SAM B 1 G442 D444 G44 D46 4.2.1.22 P35520 NLYFQSMKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQQRQMVFGVVTAIDLLNFVAA 4uuu B 1.71 BS02 SAM B 1 A421 P422 L423 G442 F443 D444 Q445 A446 V533 T535 I537 D538 A30 P31 L32 G51 F52 D53 Q54 A55 V132 T134 I136 D137 4.2.1.22 P35520 GVDLGTENLYFQSMKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQQRQMVFGVVTAIDLLNFVAAQE 4uuv A 2.80 BS02 NUC C 1 Q342 L343 W381 K385 R387 D393 K394 R397 S398 Y401 Y402 P433 D434 Q4 L5 W43 K47 R49 D55 K56 R59 S60 Y63 Y64 P95 D96 P43268 GALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPDALFSMAFPD 4uuv D 2.80 BS02 NUC F 1 Q342 L343 W381 K385 R387 M390 D393 R397 S398 Y401 Y402 P433 Q3 L4 W42 K46 R48 M51 D54 R58 S59 Y62 Y63 P94 P43268 ALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPDALFSMAFPD 4uuv G 2.80 BS02 NUC I 1 Q342 L343 W381 K385 D393 K394 R397 S398 Y401 Y402 P433 Q3 L4 W42 K46 D54 K55 R58 S59 Y62 Y63 P94 P43268 ALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPDALFSMAFPD