2m96 A BS01 CA A 1 F26 D29 K31 D33 D39 E40 F26 D29 K31 D33 D39 E40 Q8WXD0 GSMITPSCQKGYFPCGNLTKCLPRAFHCDGKDDCGNGADEENCG 3j6e A 4.70 BS01 GTP A 1 G10 Q11 Q15 N101 S140 G143 G144 T145 G146 N206 Y224 N228 G9 Q10 Q14 N90 S129 G132 G133 T134 G135 N195 Y213 N217 P02550 24855948 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 3j6e B 4.70 BS01 G2P B 1 G10 Q11 C12 Q15 A99 N101 S140 G143 G144 T145 G146 E183 N206 Y224 N228 G9 Q10 C11 Q14 A96 N98 S137 G140 G141 T142 G143 E180 N203 Y221 N225 P02554 24855948 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 3j6f A 4.90 BS01 GTP A 1 Q11 A99 N101 S140 G143 G144 T145 G146 I171 N206 Y224 N228 Q10 A88 N90 S129 G132 G133 T134 G135 I160 N195 Y213 N217 P02550 24855948 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 3j6f B 4.90 BS01 GTP A 1 N249 K254 N246 K251 P02554 24855948 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 3j6f B 4.90 BS02 GDP B 1 G10 Q11 C12 Q15 N101 G143 T145 G146 D179 E183 N206 Y224 N228 G9 Q10 C11 Q14 N98 G140 T142 G143 D176 E180 N203 Y221 N225 P02554 24855948 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 3j6g A 5.50 BS01 GTP A 1 Q11 A12 Q15 N101 S140 G143 G144 T145 G146 I171 E183 N206 Y224 N228 Q10 A11 Q14 N90 S129 G132 G133 T134 G135 I160 E172 N195 Y213 N217 P02550 24855948 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRGHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 3j6g B 5.50 BS01 GDP B 1 Q11 C12 Q15 N101 S140 G143 G144 T145 G146 E183 N206 Y224 N228 Q10 C11 Q14 N98 S137 G140 G141 T142 G143 E180 N203 Y221 N225 P02554 24855948 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 3j6g B 5.50 BS02 TA1 B 1 V23 D26 D226 H229 L230 A233 S236 F272 P274 T276 Q281 R369 L371 V22 D25 D223 H226 L227 A230 S233 F269 P271 T273 Q278 R358 L360 P02554 24855948 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 3wad A 2.00 BS01 MG A 1 E351 E355 E334 E338 Q76KZ6 MRVLMTVFANRSHLYNMVPLAWALTTAGHEVHIASHPDNVQAISDSGLTAVPVGNDLNIMAALTLNETRPEKLTWQYIHDVFAQYSQIYEYMADSTMTADLVAHARQWQPDLVIWDALTYAGPIAAEAVGAPHVRMLFGLDQWGRMRDHFNRLTGERAADDRHDPLADWLATKGEPHGVAFTESLVTGTTTLAVAPPWMSFPSEQPALSMRHLPFNGPAVLPDWLREAPSRPRVCLTLGLTLRELNVTLADFVNAVADIDADVVATFSAEQVAEIGDLPDNVRAVDFVPLHALLPSCAAIVHHGGGGTRTNAIRYGVPQLIVPNWLWDEGYVAERFAERGAALVTEVPDLTPDRLRDQLRRLIAEPSFKAAAEQIQKEYDALPSLTETVGELVRVAER 3wag A 2.10 BS01 TYD A 1 S12 N230 T283 F304 V305 P306 L307 H320 G322 G323 G324 T325 N328 S12 N216 T266 F287 V288 P289 L290 H303 G305 G306 G307 T308 N311 Q76KZ6 MRVLMTVFANRSHLYNMVPLAWALTTAGHEVHIASHPDNVQAISDSGLTAVPVGNDLNIMAALTLNETRPEKLTWQYIHDVFAQYSQIYEYMADSTMTADLVAHARQWQPDLVIWDALTYAGPIAAEAVGAPHVRMLFGLDQWGRMRDHFNRLTGERAADDRHDPLADWLATKGEPHGVAFTESLVTGTTTLAVAPPWMSFPSEQPALSMRHLPFNGPAVLPDWLREAPSRPRVCLTLGLTLRELNVTLADFVNAVADIDADVVATFSAEQVAEIGDLPDNVRAVDFVPLHALLPSCAAIVHHGGGGTRTNAIRYGVPQLIVPNWLWDEGYVAERFAERGAALVTEVPDLTPDRLRDQLRRLIAEPSFKAAAEQIQKEYDALPSLTETVGELVRVAERG 3wct A 2.40 BS01 HEM A 1 L45 F46 S48 V49 H62 R65 Q93 H94 R97 L99 N103 F104 F107 I135 I139 L45 F46 S48 V49 H62 R65 Q93 H94 R97 L99 N103 F104 F107 I135 I139 S0BBU7 DCNILQRLKVKMQWAKAYGFGTERAKFGNSLWTSIFNYAPDARDLFKSVKSEDMRSPQFKAHIARVIGGLDRVISMFDNEDALNADLEHLKSQHDPRGLDALNFVVFGKALFATVGGQFGVCFDLPAWESCYKVIAMGITGNDMFS 3wct A 2.40 BS02 OXY A 1 W32 F46 H62 V66 W32 F46 H62 V66 S0BBU7 DCNILQRLKVKMQWAKAYGFGTERAKFGNSLWTSIFNYAPDARDLFKSVKSEDMRSPQFKAHIARVIGGLDRVISMFDNEDALNADLEHLKSQHDPRGLDALNFVVFGKALFATVGGQFGVCFDLPAWESCYKVIAMGITGNDMFS 3wct A 2.40 BS03 HEM D 1 H89 Q93 H89 Q93 S0BBU7 DCNILQRLKVKMQWAKAYGFGTERAKFGNSLWTSIFNYAPDARDLFKSVKSEDMRSPQFKAHIARVIGGLDRVISMFDNEDALNADLEHLKSQHDPRGLDALNFVVFGKALFATVGGQFGVCFDLPAWESCYKVIAMGITGNDMFS 3wct B 2.40 BS01 HEM B 1 M46 F47 R49 V50 H63 R66 L91 Q94 H95 R98 V100 Q104 Y105 V108 I141 M46 F47 R49 V50 H63 R66 L91 Q94 H95 R98 V100 Q104 Y105 V108 I141 S0BBR6 SECGPLQRLKVKRQWAEAYGSGNGREEFGHFIWANVFKVAPSARDMFKRVRGDNIYTPAFRAHATRVLGGLDMCVALLDDESVLNTQLAHLASQHSSRGVSAEQYNVVEHAVMMGVEHEIGQNVFDKDAWQACLDVITSGIQGN 3wct B 2.40 BS02 OXY B 1 W33 F47 H63 V67 W33 F47 H63 V67 S0BBR6 SECGPLQRLKVKRQWAEAYGSGNGREEFGHFIWANVFKVAPSARDMFKRVRGDNIYTPAFRAHATRVLGGLDMCVALLDDESVLNTQLAHLASQHSSRGVSAEQYNVVEHAVMMGVEHEIGQNVFDKDAWQACLDVITSGIQGN 3wct B 2.40 BS03 CA B 1 N106 E109 D135 N106 E109 D135 S0BBR6 SECGPLQRLKVKRQWAEAYGSGNGREEFGHFIWANVFKVAPSARDMFKRVRGDNIYTPAFRAHATRVLGGLDMCVALLDDESVLNTQLAHLASQHSSRGVSAEQYNVVEHAVMMGVEHEIGQNVFDKDAWQACLDVITSGIQGN 3wct B 2.40 BS04 HEM C 1 H90 Q94 H90 Q94 S0BBR6 SECGPLQRLKVKRQWAEAYGSGNGREEFGHFIWANVFKVAPSARDMFKRVRGDNIYTPAFRAHATRVLGGLDMCVALLDDESVLNTQLAHLASQHSSRGVSAEQYNVVEHAVMMGVEHEIGQNVFDKDAWQACLDVITSGIQGN 3wct C 2.40 BS01 HEM B 1 H94 Q98 H94 Q98 S0BCU7 SSNSCTTEDRREMQLMWANVWSAQFTGRRLAIAQAVFKDLFAHVPDAVGLFDRVHGTEIDSSEFKAHCIRVVNGLDSAIGLLSDPSTLNEQLSHLATQHQERAGVTKGGFSAIAQSFLRVMPQVASCFNPDAWSRCFNRITNGMTEGLAE 3wct C 2.40 BS02 HEM C 1 L50 F51 R53 V54 H67 R70 V71 L75 Q98 H99 R102 G109 F110 I113 T141 M144 L50 F51 R53 V54 H67 R70 V71 L75 Q98 H99 R102 G109 F110 I113 T141 M144 S0BCU7 SSNSCTTEDRREMQLMWANVWSAQFTGRRLAIAQAVFKDLFAHVPDAVGLFDRVHGTEIDSSEFKAHCIRVVNGLDSAIGLLSDPSTLNEQLSHLATQHQERAGVTKGGFSAIAQSFLRVMPQVASCFNPDAWSRCFNRITNGMTEGLAE 3wct C 2.40 BS03 OXY C 1 F37 F51 H67 V71 F37 F51 H67 V71 S0BCU7 SSNSCTTEDRREMQLMWANVWSAQFTGRRLAIAQAVFKDLFAHVPDAVGLFDRVHGTEIDSSEFKAHCIRVVNGLDSAIGLLSDPSTLNEQLSHLATQHQERAGVTKGGFSAIAQSFLRVMPQVASCFNPDAWSRCFNRITNGMTEGLAE 3wct D 2.40 BS01 HEM A 1 H94 Q98 H92 Q96 S0BAP9 FCSEADATIVIKQWNQIYNAGIGAKSRWTMGNEIFSSLFKLKPESEVLFNNVNVANMSSGAFHAHTVRVLSGLDMGINYLNDAGTLTSLTAHLAAQHVARTGLKAVYFDAMGKVLMTVLPSLIDNFNPDAWRNCLLPLKNAIAKGLP 3wct D 2.40 BS02 HEM D 1 L50 F51 N53 V54 H67 R70 V71 L95 Q98 H99 R102 L105 Y109 F110 M113 L48 F49 N51 V52 H65 R68 V69 L93 Q96 H97 R100 L103 Y107 F108 M111 S0BAP9 FCSEADATIVIKQWNQIYNAGIGAKSRWTMGNEIFSSLFKLKPESEVLFNNVNVANMSSGAFHAHTVRVLSGLDMGINYLNDAGTLTSLTAHLAAQHVARTGLKAVYFDAMGKVLMTVLPSLIDNFNPDAWRNCLLPLKNAIAKGLP 3wct D 2.40 BS03 OXY D 1 F37 F51 H67 V71 F35 F49 H65 V69 S0BAP9 FCSEADATIVIKQWNQIYNAGIGAKSRWTMGNEIFSSLFKLKPESEVLFNNVNVANMSSGAFHAHTVRVLSGLDMGINYLNDAGTLTSLTAHLAAQHVARTGLKAVYFDAMGKVLMTVLPSLIDNFNPDAWRNCLLPLKNAIAKGLP 3wct D 2.40 BS04 FUC D 1 N58 S61 N56 S59 S0BAP9 FCSEADATIVIKQWNQIYNAGIGAKSRWTMGNEIFSSLFKLKPESEVLFNNVNVANMSSGAFHAHTVRVLSGLDMGINYLNDAGTLTSLTAHLAAQHVARTGLKAVYFDAMGKVLMTVLPSLIDNFNPDAWRNCLLPLKNAIAKGLP 3wct G 2.40 BS02 HEM G 1 L50 F51 R53 V54 H67 R70 V71 L75 L95 Q98 H99 R102 V105 G109 F110 I113 F137 M144 L50 F51 R53 V54 H67 R70 V71 L75 L95 Q98 H99 R102 V105 G109 F110 I113 F137 M144 S0BCU7 SSNSCTTEDRREMQLMWANVWSAQFTGRRLAIAQAVFKDLFAHVPDAVGLFDRVHGTEIDSSEFKAHCIRVVNGLDSAIGLLSDPSTLNEQLSHLATQHQERAGVTKGGFSAIAQSFLRVMPQVASCFNPDAWSRCFNRITNGMTEGLAE 3wct H 2.40 BS04 FUC H 1 S61 G62 S59 G60 S0BAP9 FCSEADATIVIKQWNQIYNAGIGAKSRWTMGNEIFSSLFKLKPESEVLFNNVNVANMSSGAFHAHTVRVLSGLDMGINYLNDAGTLTSLTAHLAAQHVARTGLKAVYFDAMGKVLMTVLPSLIDNFNPDAWRNCLLPLKNAIAKGLP 3wcu A 2.90 BS01 HEM A 1 L45 F46 S48 V49 H62 V66 L70 H94 R97 L99 N103 F104 F107 I135 I139 L45 F46 S48 V49 H62 V66 L70 H94 R97 L99 N103 F104 F107 I135 I139 S0BBU7 DCNILQRLKVKMQWAKAYGFGTERAKFGNSLWTSIFNYAPDARDLFKSVKSEDMRSPQFKAHIARVIGGLDRVISMFDNEDALNADLEHLKSQHDPRGLDALNFVVFGKALFATVGGQFGVCFDLPAWESCYKVIAMGITGNDMFS 3wcu B 2.90 BS02 HEM B 1 M46 F47 R49 V50 H63 R66 G70 L71 L91 Q94 H95 R98 V100 Y105 I141 M46 F47 R49 V50 H63 R66 G70 L71 L91 Q94 H95 R98 V100 Y105 I141 S0BBR6 SECGPLQRLKVKRQWAEAYGSGNGREEFGHFIWANVFKVAPSARDMFKRVRGDNIYTPAFRAHATRVLGGLDMCVALLDDESVLNTQLAHLASQHSSRGVSAEQYNVVEHAVMMGVEHEIGQNVFDKDAWQACLDVITSGIQGN 3wcu D 2.90 BS02 HEM D 1 S47 L50 F51 N53 V54 H67 R70 V71 L75 H99 R102 L105 Y109 F110 M113 I144 S47 L50 F51 N53 V54 H67 R70 V71 L75 H99 R102 L105 Y109 F110 M113 I144 S0BAP9 SEFCSEADATIVIKQWNQIYNAGIGAKSRWTMGNEIFSSLFKLKPESEVLFNNVNVANMSSGAFHAHTVRVLSGLDMGINYLNDAGTLTSLTAHLAAQHVARTGLKAVYFDAMGKVLMTVLPSLIDNFNPDAWRNCLLPLKNAIAKGLP 3wcv D 2.60 BS02 HEM D 1 S47 L50 F51 N53 V54 H67 R70 V71 L75 L95 Q98 H99 R102 Y109 F110 M113 S45 L48 F49 N51 V52 H65 R68 V69 L73 L93 Q96 H97 R100 Y107 F108 M111 S0BAP9 FCSEADATIVIKQWNQIYNAGIGAKSRWTMGNEIFSSLFKLKPESEVLFNNVNVANMSSGAFHAHTVRVLSGLDMGINYLNDAGTLTSLTAHLAAQHVARTGLKAVYFDAMGKVLMTVLPSLIDNFNPDAWRNCLLPLKNAIAKGLP 3wcv E 2.60 BS01 HEM E 1 L45 F46 S48 V49 H62 R65 L90 Q93 H94 R97 L99 N103 F104 F107 Y132 I139 L45 F46 S48 V49 H62 R65 L90 Q93 H94 R97 L99 N103 F104 F107 Y132 I139 S0BBU7 DCNILQRLKVKMQWAKAYGFGTERAKFGNSLWTSIFNYAPDARDLFKSVKSEDMRSPQFKAHIARVIGGLDRVISMFDNEDALNADLEHLKSQHDPRGLDALNFVVFGKALFATVGGQFGVCFDLPAWESCYKVIAMGITGNDMFS 3wcv F 2.60 BS04 CA F 2 G99 S101 G99 S101 S0BBR6 SECGPLQRLKVKRQWAEAYGSGNGREEFGHFIWANVFKVAPSARDMFKRVRGDNIYTPAFRAHATRVLGGLDMCVALLDDESVLNTQLAHLASQHSSRGVSAEQYNVVEHAVMMGVEHEIGQNVFDKDAWQACLDVITSGIQGN 3wcw B 2.50 BS01 HEM B 1 M46 F47 R49 V50 H63 R66 Q94 H95 R98 V100 Q104 Y105 V108 M46 F47 R49 V50 H63 R66 Q94 H95 R98 V100 Q104 Y105 V108 S0BBR6 SECGPLQRLKVKRQWAEAYGSGNGREEFGHFIWANVFKVAPSARDMFKRVRGDNIYTPAFRAHATRVLGGLDMCVALLDDESVLNTQLAHLASQHSSRGVSAEQYNVVEHAVMMGVEHEIGQNVFDKDAWQACLDVITSGIQGN 3wcw F 2.50 BS01 HEM F 1 M46 F47 R49 H63 R66 V67 L71 L91 Q94 H95 R98 V100 Q104 Y105 V108 M46 F47 R49 H63 R66 V67 L71 L91 Q94 H95 R98 V100 Q104 Y105 V108 S0BBR6 SECGPLQRLKVKRQWAEAYGSGNGREEFGHFIWANVFKVAPSARDMFKRVRGDNIYTPAFRAHATRVLGGLDMCVALLDDESVLNTQLAHLASQHSSRGVSAEQYNVVEHAVMMGVEHEIGQNVFDKDAWQACLDVITSGIQGN 3wcw G 2.50 BS02 HEM G 1 L50 F51 R53 V54 H67 R70 V71 G74 L75 Q98 H99 R102 V105 G109 F110 I113 T141 M144 L50 F51 R53 V54 H67 R70 V71 G74 L75 Q98 H99 R102 V105 G109 F110 I113 T141 M144 S0BCU7 SSNSCTTEDRREMQLMWANVWSAQFTGRRLAIAQAVFKDLFAHVPDAVGLFDRVHGTEIDSSEFKAHCIRVVNGLDSAIGLLSDPSTLNEQLSHLATQHQERAGVTKGGFSAIAQSFLRVMPQVASCFNPDAWSRCFNRITNGMTEGLAE 3wcw G 2.50 BS03 OXY G 1 F51 H67 V71 F51 H67 V71 S0BCU7 SSNSCTTEDRREMQLMWANVWSAQFTGRRLAIAQAVFKDLFAHVPDAVGLFDRVHGTEIDSSEFKAHCIRVVNGLDSAIGLLSDPSTLNEQLSHLATQHQERAGVTKGGFSAIAQSFLRVMPQVASCFNPDAWSRCFNRITNGMTEGLAE 3wdi A 2.20 BS01 MLR A 1 W297 Y299 N300 H347 R411 D413 L414 E442 H525 D526 N581 Y583 W289 Y291 N292 H339 R403 D405 L406 E434 H517 D518 N573 Y575 3.2.1.41 K9L0H1 QSFEAYLDELTMITILFPCHVDQKRAPIFFLRDDKKTAYRLTIRSSEKHHSFIKYECLVPFIVELGKRYVVYTEEGWQVPLQVGAVMRTKAFDDLYAYDGNDLGATYDPEKTTFKVWAPTATDVLLKLIHPTTKEETTYVMTREKKGLWTYTVYDDVERFLYTYMTYVNFIWREAVDPYAKSVSVNGTYGVVVDLAKTNIPKPSMSLFISMTDAIIYEMHIRDFTIHHESGVRQKGKYVGLTERGTTGPNGTLTGLSYIKQLGVTHVQLMPVQDFEGVDELQPLKMYNWGYNTVHYNAPEGSYATDPDDPYARIIELKRAIRAFQQEGIRVILDVVYNHVYVRETSSFEHLVPGYYFRYERNGYPSNGTGVGNDLASERKMVKKFIIDSVTYWLKEYGVDGFRFDLMGILDIDTMNDVRRAIDEIDPTVIILGEGWDLATPLPSEKKTTIANAKHTPRIAYFNDRFRDYVKGSTFDIHERGFALGDCSYKEAVIGAIRGSIHLFFSPRQSVNYVECHDNHTLWDKMAVANAHESEYIRRKRQKLATAIVLLSQGIPFLHSGQEFYRTKKGVENSYNSPDEVNQVDWNEKSRWEEDVREIMKLIELRKKHGAFRFLTADQVRRHMKFYDTHPSVIAYQLVDVGVYGPWKQIVVVYHNEEKKAMLPLADGKWKVMFSSGNVCEQFIEINGIGAWVLIQC 3wdi A 2.20 BS02 MLR A 2 W444 L446 D472 R475 F483 N527 W436 L438 D464 R467 F475 N519 3.2.1.41 K9L0H1 QSFEAYLDELTMITILFPCHVDQKRAPIFFLRDDKKTAYRLTIRSSEKHHSFIKYECLVPFIVELGKRYVVYTEEGWQVPLQVGAVMRTKAFDDLYAYDGNDLGATYDPEKTTFKVWAPTATDVLLKLIHPTTKEETTYVMTREKKGLWTYTVYDDVERFLYTYMTYVNFIWREAVDPYAKSVSVNGTYGVVVDLAKTNIPKPSMSLFISMTDAIIYEMHIRDFTIHHESGVRQKGKYVGLTERGTTGPNGTLTGLSYIKQLGVTHVQLMPVQDFEGVDELQPLKMYNWGYNTVHYNAPEGSYATDPDDPYARIIELKRAIRAFQQEGIRVILDVVYNHVYVRETSSFEHLVPGYYFRYERNGYPSNGTGVGNDLASERKMVKKFIIDSVTYWLKEYGVDGFRFDLMGILDIDTMNDVRRAIDEIDPTVIILGEGWDLATPLPSEKKTTIANAKHTPRIAYFNDRFRDYVKGSTFDIHERGFALGDCSYKEAVIGAIRGSIHLFFSPRQSVNYVECHDNHTLWDKMAVANAHESEYIRRKRQKLATAIVLLSQGIPFLHSGQEFYRTKKGVENSYNSPDEVNQVDWNEKSRWEEDVREIMKLIELRKKHGAFRFLTADQVRRHMKFYDTHPSVIAYQLVDVGVYGPWKQIVVVYHNEEKKAMLPLADGKWKVMFSSGNVCEQFIEINGIGAWVLIQC 3wdi A 2.20 BS03 MLR A 3 Y14 D16 L24 K62 V91 G92 A93 M95 R96 Y367 Y6 D8 L16 K54 V83 G84 A85 M87 R88 Y359 3.2.1.41 K9L0H1 QSFEAYLDELTMITILFPCHVDQKRAPIFFLRDDKKTAYRLTIRSSEKHHSFIKYECLVPFIVELGKRYVVYTEEGWQVPLQVGAVMRTKAFDDLYAYDGNDLGATYDPEKTTFKVWAPTATDVLLKLIHPTTKEETTYVMTREKKGLWTYTVYDDVERFLYTYMTYVNFIWREAVDPYAKSVSVNGTYGVVVDLAKTNIPKPSMSLFISMTDAIIYEMHIRDFTIHHESGVRQKGKYVGLTERGTTGPNGTLTGLSYIKQLGVTHVQLMPVQDFEGVDELQPLKMYNWGYNTVHYNAPEGSYATDPDDPYARIIELKRAIRAFQQEGIRVILDVVYNHVYVRETSSFEHLVPGYYFRYERNGYPSNGTGVGNDLASERKMVKKFIIDSVTYWLKEYGVDGFRFDLMGILDIDTMNDVRRAIDEIDPTVIILGEGWDLATPLPSEKKTTIANAKHTPRIAYFNDRFRDYVKGSTFDIHERGFALGDCSYKEAVIGAIRGSIHLFFSPRQSVNYVECHDNHTLWDKMAVANAHESEYIRRKRQKLATAIVLLSQGIPFLHSGQEFYRTKKGVENSYNSPDEVNQVDWNEKSRWEEDVREIMKLIELRKKHGAFRFLTADQVRRHMKFYDTHPSVIAYQLVDVGVYGPWKQIVVVYHNEEKKAMLPLADGKWKVMFSSGNVCEQFIEINGIGAWVLIQC 3wig A 2.70 BS01 ANP A 1 L75 G76 A77 G78 A96 K98 E145 M147 S151 Q154 K193 S195 N196 L198 D209 L14 G15 A16 G17 A32 K34 E81 M83 S87 Q90 K129 S131 N132 L134 D145 2.7.12.2 Q02750 24746704 MELKDDDFEKISELGAGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIG 3wig A 2.70 BS03 CHU A 1 L119 V128 G129 I142 M144 H189 R190 D191 C208 D209 F210 G211 V212 S213 L216 I217 M220 N222 L55 V64 G65 I78 M80 H125 R126 D127 C144 D145 F146 G147 V148 S149 L152 I153 M156 N158 2.7.12.2 Q02750 24746704 MELKDDDFEKISELGAGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIG 3ws8 A 2.60 BS02 X4C A 1 S677 V678 I692 Y693 F696 P712 M713 G725 Q726 G728 F729 S231 V232 I246 Y247 F250 P266 M267 G279 Q280 G282 F283 3.1.4.17,3.1.4.35 Q9Y233 24837154 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 3ws8 B 2.60 BS03 X4C B 1 Y693 P712 M713 E721 G725 Q726 G728 F729 Y247 P266 M267 E275 G279 Q280 G282 F283 3.1.4.17,3.1.4.35 Q9Y233 24837154 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 3ws9 A 2.99 BS03 X4D A 1 Y693 F696 P712 M713 G725 Q726 G728 F729 Y247 F250 P266 M267 G279 Q280 G282 F283 3.1.4.17,3.1.4.35 Q9Y233 24837154 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 3ws9 B 2.99 BS02 MG B 1 H563 D564 D674 H117 D118 D228 3.1.4.17,3.1.4.35 Q9Y233 24837154 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 3ws9 B 2.99 BS03 X4D B 1 L675 S677 Y693 P712 M713 E721 G725 Q726 G728 F729 L229 S231 Y247 P266 M267 E275 G279 Q280 G282 F283 3.1.4.17,3.1.4.35 Q9Y233 24837154 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEE 4bp1 A 2.17 BS01 MTA A 1 Q33 L49 G85 G86 D88 C107 E108 I109 V113 D139 A140 D157 S158 S159 P164 A165 T167 L168 Q32 L48 G84 G85 D87 C106 E107 I108 V112 D138 A139 D156 S157 S158 P163 A164 T166 L167 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4bp1 A 2.17 BS02 PUT A 1 I53 Q54 Y63 D157 S158 D160 Y225 I52 Q53 Y62 D156 S157 D159 Y224 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4bp1 B 2.17 BS01 MTA B 1 Q33 L49 Q54 G85 G86 D88 C107 E108 I109 D110 V113 D139 A140 D157 S158 S159 P164 A165 T167 L168 Q32 L48 Q53 G84 G85 D87 C106 E107 I108 D109 V112 D138 A139 D156 S157 S158 P163 A164 T166 L167 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIEN 4bp1 C 2.17 BS01 MTA C 1 Q33 L49 Q54 G85 G86 D88 C107 E108 I109 V113 E138 D139 A140 D157 S158 S159 P164 A165 T167 L168 Q32 L48 Q53 G84 G85 D87 C106 E107 I108 V112 E137 D138 A139 D156 S157 S158 P163 A164 T166 L167 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4bp1 C 2.17 BS02 PUT C 1 V52 Q54 Y63 D157 S158 D160 Y225 I230 V51 Q53 Y62 D156 S157 D159 Y224 I229 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4c69 X 2.28 BS01 ATP X 1 K12 K20 K12 K20 Q60932 MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 4cis A 2.05 BS01 NUC C 1 F111 N128 K130 F111 N128 K130 3.2.2.23 Q031W6 PELPEVETVRRELEKRIVGQKIISIEATYPRMVLTGFEQLKKELTGKIIQGIIRRGKYLIFEIGDDFRLISHLRMEGKYRLATLDAPREKHDHLTMKFSDGQLIYADVRKFGTWELISTDQVLPYFLNKKIGPEPTYEDFDEKLFREKLRKSTKKIKPYLLEQTLVAGLGNIYVDEVLWLAKIHPEKEANQLIESSIHLLHDSIIEILQKAIKLGGSSITGKMQNELQVYGKTGEKCSRCGAEIQKIKVAGRGTHFCPFCQQK 4cis A 2.05 BS02 NUC D 1 E2 K57 H72 R74 M75 K129 L161 E162 Q163 G170 N171 R260 E2 K57 H72 R74 M75 K129 L161 E162 Q163 G170 N171 R252 3.2.2.23 Q031W6 PELPEVETVRRELEKRIVGQKIISIEATYPRMVLTGFEQLKKELTGKIIQGIIRRGKYLIFEIGDDFRLISHLRMEGKYRLATLDAPREKHDHLTMKFSDGQLIYADVRKFGTWELISTDQVLPYFLNKKIGPEPTYEDFDEKLFREKLRKSTKKIKPYLLEQTLVAGLGNIYVDEVLWLAKIHPEKEANQLIESSIHLLHDSIIEILQKAIKLGGSSITGKMQNELQVYGKTGEKCSRCGAEIQKIKVAGRGTHFCPFCQQK 4cis A 2.05 BS04 BU3 A 1 Y58 H72 R74 T113 K129 Y58 H72 R74 T113 K129 3.2.2.23 Q031W6 PELPEVETVRRELEKRIVGQKIISIEATYPRMVLTGFEQLKKELTGKIIQGIIRRGKYLIFEIGDDFRLISHLRMEGKYRLATLDAPREKHDHLTMKFSDGQLIYADVRKFGTWELISTDQVLPYFLNKKIGPEPTYEDFDEKLFREKLRKSTKKIKPYLLEQTLVAGLGNIYVDEVLWLAKIHPEKEANQLIESSIHLLHDSIIEILQKAIKLGGSSITGKMQNELQVYGKTGEKCSRCGAEIQKIKVAGRGTHFCPFCQQK 4cis B 2.05 BS01 NUC C 1 K90 H91 V108 R109 K110 F111 T153 K154 K155 A258 K90 H91 V108 R109 K110 F111 T153 K154 K155 A254 3.2.2.23 Q031W6 PELPEVETVRRELEKRIVGQKIISIEATYPRMVLTGFEQLKKELTGKIIQGIIRRGKYLIFEIGDDFRLISHLRMEGKYRLATLDAPREKHDHLTMKFSDGQLIYADVRKFGTWELISTDQVLPYFLNKKIGPEPTYEDFDEKLFREKLRKSTKKIKPYLLEQTLVAGLGNIYVDEVLWLAKIHPEKEANQLIESSIHLLHDSIIEILQKAIKLGGSSIRLGSTGKMQNELQVYGKTGEKCSRCGAEIQKIKVAGRGTHFCPFCQQK 4cis B 2.05 BS02 NUC D 1 P1 E2 K57 H72 R74 M75 R109 K129 G170 N171 I172 I219 R220 Y238 K254 K256 R260 G261 P1 E2 K57 H72 R74 M75 R109 K129 G170 N171 I172 I219 R220 Y234 K250 K252 R256 G257 3.2.2.23 Q031W6 PELPEVETVRRELEKRIVGQKIISIEATYPRMVLTGFEQLKKELTGKIIQGIIRRGKYLIFEIGDDFRLISHLRMEGKYRLATLDAPREKHDHLTMKFSDGQLIYADVRKFGTWELISTDQVLPYFLNKKIGPEPTYEDFDEKLFREKLRKSTKKIKPYLLEQTLVAGLGNIYVDEVLWLAKIHPEKEANQLIESSIHLLHDSIIEILQKAIKLGGSSIRLGSTGKMQNELQVYGKTGEKCSRCGAEIQKIKVAGRGTHFCPFCQQK 4csu 0 5.50 BS01 NUC B 1 S1 R2 K9 R10 T13 N15 N16 R17 S18 H19 A20 L21 N22 T24 R26 R27 F28 L29 P30 N31 H33 H35 R36 E42 K43 R44 F45 R49 A52 K53 M55 R56 V57 K60 K61 Y77 S1 R2 K9 R10 T13 N15 N16 R17 S18 H19 A20 L21 N22 T24 R26 R27 F28 L29 P30 N31 H33 H35 R36 E42 K43 R44 F45 R49 A52 K53 M55 R56 V57 K60 K61 Y77 P0A7M2 24844575 SRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY 4csu 1 5.50 BS01 NUC B 1 M1 K2 Q38 Q39 S40 H41 L43 K44 R47 R48 A51 R52 K54 T55 L56 N58 E59 M1 K2 Q38 Q39 S40 H41 L43 K44 R47 R48 A51 R52 K54 T55 L56 N58 E59 P0A7M6 24844575 MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA 4csu 2 5.50 BS01 NUC A 1 R15 L16 H19 F52 M53 R15 L16 H19 F52 M53 P0AG51 24844575 AKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAVSFMVKVEE 4csu 2 5.50 BS02 NUC B 1 R10 S11 I13 G14 K18 A21 T22 L24 G25 G27 R29 R30 I31 H33 R37 A42 I43 G45 M46 R10 S11 I13 G14 K18 A21 T22 L24 G25 G27 R29 R30 I31 H33 R37 A42 I43 G45 M46 P0AG51 24844575 AKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAVSFMVKVEE 4csu 3 5.50 BS01 NUC B 1 A1 V2 Q3 Q4 N5 K6 P7 T8 R9 S10 K11 R12 G13 M14 R15 R16 S17 H18 D19 S26 S28 V29 K31 H37 R39 H40 H41 Y48 R49 R51 K56 A1 V2 Q3 Q4 N5 K6 P7 T8 R9 S10 K11 R12 G13 M14 R15 R16 S17 H18 D19 S26 S28 V29 K31 H37 R39 H40 H41 Y48 R49 R51 K56 P0A7N4 24844575 AVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRGRKVIAK 4csu 4 5.50 BS01 NUC B 1 G3 I4 R5 K7 K9 F19 Y20 T21 T22 K24 N25 K29 E31 L35 K36 K37 F38 P40 R43 Q44 H45 K52 G1 I2 R3 K5 K7 F17 Y18 T19 T20 K22 N23 K27 E29 L33 K34 K35 F36 P38 R41 Q42 H43 K50 P0A7N9 24844575 GIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAK 4csu 5 5.50 BS01 NUC B 1 M1 A2 K3 L4 T5 K6 R7 M8 R9 R12 E13 V15 D16 A17 T18 E32 L33 T35 V39 E40 S41 A45 K54 T69 G70 R71 S72 R74 I104 K105 K106 G107 E108 M109 N110 F111 D112 L127 G128 V130 L131 G132 P133 R134 G135 L136 R162 R164 N165 D166 K167 N168 I170 H172 T173 T174 K177 S215 T216 T217 M218 G219 G221 M1 A2 K3 L4 T5 K6 R7 M8 R9 R12 E13 V15 D16 A17 T18 E32 L33 T35 V39 E40 S41 A45 K54 T69 G70 R71 S72 R74 I104 K105 K106 G107 E108 M109 N110 F111 D112 L127 G128 V130 L131 G132 P133 R134 G135 L136 R162 R164 N165 D166 K167 N168 I170 H172 T173 T174 K177 S215 T216 T217 M218 G219 G221 P0A7L0 24844575 MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTMGAGVAVDQAGLSASVN 4csu 6 5.50 BS01 NUC B 1 M1 K2 R3 T4 F5 Q6 P7 S8 V9 L10 R12 N13 R14 H16 G17 F18 R19 A20 R21 M22 K25 N26 R28 Q29 V30 R33 R34 K37 G38 R39 R41 L42 T43 S45 K46 M1 K2 R3 T4 F5 Q6 P7 S8 V9 L10 R12 N13 R14 H16 G17 F18 R19 A20 R21 M22 K25 N26 R28 Q29 V30 R33 R34 K37 G38 R39 R41 L42 T43 S45 K46 P0A7P5 24844575 MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK 4csu 7 5.50 BS01 NUC B 1 P1 K2 I3 K4 T5 V6 R7 G8 K14 K15 T16 G17 K18 K22 K24 H25 A26 N27 L28 R29 H30 I31 L32 T33 K34 K35 T37 K38 R39 K40 R41 L43 R44 K46 S50 K51 P62 Y63 A64 P1 K2 I3 K4 T5 V6 R7 G8 K14 K15 T16 G17 K18 K22 K24 H25 A26 N27 L28 R29 H30 I31 L32 T33 K34 K35 T37 K38 R39 K40 R41 L43 R44 K46 S50 K51 P62 Y63 A64 P0A7Q1 24844575 PKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA 4csu 8 5.50 BS01 NUC B 1 M1 K2 V3 R4 A5 S6 V7 K8 L10 R12 I16 K18 R19 D20 G21 R24 P31 K32 H33 K34 R36 Q37 G38 M1 K2 V3 R4 A5 S6 V7 K8 L10 R12 I16 K18 R19 D20 G21 R24 P31 K32 H33 K34 R36 Q37 G38 P0A7Q6 24844575 MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG 4csu 9 5.50 BS01 NUC B 1 V21 F23 R24 R25 E26 K27 Y28 I29 P30 K31 G32 G33 P34 D35 E51 N52 N54 T55 L56 D58 Y59 R60 F61 E62 K63 R66 R76 D77 C78 T79 G80 K81 R82 T128 R129 K131 S132 S133 V134 N135 R136 R139 K141 R177 A181 A182 K183 P184 K185 F191 T192 T193 L194 V200 R202 E206 K207 S208 L217 E219 E223 G224 A225 L227 G228 I229 R230 F231 V18 F20 R21 R22 E23 K24 Y25 I26 P27 K28 G29 G30 P31 D32 E48 N49 N51 T52 L53 D55 Y56 R57 F58 E59 K60 R63 R73 D74 C75 T76 G77 K78 R79 T125 R126 K128 S129 S130 V131 N132 R133 R136 K138 R174 A178 A179 K180 P181 K182 F188 T189 T190 L191 V197 R199 E203 K204 S205 L214 E216 E220 G221 A222 L224 G225 I226 R227 F228 P42641 24844575 VDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLATKPRWLVFNKIDLLDKVEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIENP 4csu C 5.50 BS01 NUC B 1 K6 P7 T8 P10 R12 R13 H14 V19 L23 K25 K27 F29 K35 N36 K38 S39 G40 G41 R42 N43 N44 N45 G46 R47 I48 T49 T50 R51 H52 H57 K58 Q59 A60 Y61 R62 V76 E81 Y82 P84 N85 R86 S87 L94 Y95 K96 G98 R100 M145 K146 P147 G148 K149 Q152 L153 A154 R155 S156 A157 G158 T159 L175 R176 S177 E179 R181 E184 A197 H199 M200 R202 V203 L204 G205 K206 A207 G208 A210 R211 W212 R213 R216 P217 T218 V219 R220 G221 T222 A223 M224 N225 V227 H231 G232 G233 G234 E235 G236 R237 N238 F239 G240 K241 H242 P243 T245 W247 Q250 T251 K252 G253 K254 K255 T256 R257 N259 K260 R261 K264 F265 R269 R270 K6 P7 T8 P10 R12 R13 H14 V19 L23 K25 K27 F29 K35 N36 K38 S39 G40 G41 R42 N43 N44 N45 G46 R47 I48 T49 T50 R51 H52 H57 K58 Q59 A60 Y61 R62 V76 E81 Y82 P84 N85 R86 S87 L94 Y95 K96 G98 R100 M145 K146 P147 G148 K149 Q152 L153 A154 R155 S156 A157 G158 T159 L175 R176 S177 E179 R181 E184 A197 H199 M200 R202 V203 L204 G205 K206 A207 G208 A210 R211 W212 R213 R216 P217 T218 V219 R220 G221 T222 A223 M224 N225 V227 H231 G232 G233 G234 E235 G236 R237 N238 F239 G240 K241 H242 P243 T245 W247 Q250 T251 K252 G253 K254 K255 T256 R257 N259 K260 R261 K264 F265 R269 R270 P60422 24844575 AVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRS 4csu D 5.50 BS01 NUC B 1 M11 T12 R13 P23 V24 Q36 K38 N42 D43 Y45 Q49 K55 K56 N58 R59 T61 K62 P63 G66 H67 K70 R77 L79 W80 E81 R83 S113 K114 G115 K116 G117 F118 V122 R124 W125 N126 F127 R128 A132 T133 H134 G135 S137 L138 H140 R141 V142 P143 G144 S145 I146 G147 Q148 N149 Q150 T151 G153 K154 V155 F156 K157 G158 K159 K160 M161 A162 G163 Q164 M165 N167 R169 V170 T171 Q173 S174 L175 K190 G191 A192 V193 P194 G195 A196 T197 K208 A209 M11 T12 R13 P23 V24 Q36 K38 N42 D43 Y45 Q49 K55 K56 N58 R59 T61 K62 P63 G66 H67 K70 R77 L79 W80 E81 R83 S113 K114 G115 K116 G117 F118 V122 R124 W125 N126 F127 R128 A132 T133 H134 G135 S137 L138 H140 R141 V142 P143 G144 S145 I146 G147 Q148 N149 Q150 T151 G153 K154 V155 F156 K157 G158 K159 K160 M161 A162 G163 Q164 M165 N167 R169 V170 T171 Q173 S174 L175 K190 G191 A192 V193 P194 G195 A196 T197 K208 A209 P60438 24844575 MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA 4csu E 5.50 BS01 NUC B 1 R21 N24 A26 H29 Q30 Y35 A36 G38 A39 R40 Q41 T43 R44 Q46 K47 T48 R49 A50 V52 T53 G54 S55 K57 K58 W60 Q62 K63 G64 T65 G66 R67 A68 R69 S70 G71 S75 P76 I77 W78 R79 S80 T84 F85 R88 H92 Q94 K95 V96 N97 K98 K99 M100 Y101 R102 P129 K130 T131 K132 L159 R162 N163 L164 H165 T173 G174 I175 D176 M199 R21 N24 A26 H29 Q30 Y35 A36 G38 A39 R40 Q41 T43 R44 Q46 K47 T48 R49 A50 V52 T53 G54 S55 K57 K58 W60 Q62 K63 G64 T65 G66 R67 A68 R69 S70 G71 S75 P76 I77 W78 R79 S80 T84 F85 R88 H92 Q94 K95 V96 N97 K98 K99 M100 Y101 R102 P129 K130 T131 K132 L159 R162 N163 L164 H165 T173 G174 I175 D176 M199 P60723 24844575 MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA 4csu F 5.50 BS01 NUC A 1 N22 S23 V24 M25 Q26 R29 K32 Q62 K63 P64 L65 V88 T89 R91 R94 W96 N22 S23 V24 M25 Q26 R29 K32 Q62 K63 P64 L65 V88 T89 R91 R94 W96 P62399 24844575 AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK 4csu F 5.50 BS02 NUC B 1 T34 N36 M37 G38 G40 E41 T67 K68 R70 K71 S72 V73 A74 G75 F76 I84 G85 L116 S117 S120 F121 D122 G123 N126 S128 G130 V131 R132 D146 R147 V148 G150 L151 D152 T154 T34 N36 M37 G38 G40 E41 T67 K68 R70 K71 S72 V73 A74 G75 F76 I84 G85 L116 S117 S120 F121 D122 G123 N126 S128 G130 V131 R132 D146 R147 V148 G150 L151 D152 T154 P62399 24844575 AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK 4csu G 5.50 BS01 NUC B 1 S1 R2 V3 L36 D38 W61 A62 Q63 G65 T66 A69 L70 F82 Y93 L106 G107 F108 S109 H110 K137 Q138 G141 Q142 A145 R148 R152 Y156 K157 Y163 K171 A173 K175 K176 S1 R2 V3 L35 D37 W60 A61 Q62 G64 T65 A68 L69 F81 Y92 L105 G106 F107 S108 H109 K136 Q137 G140 Q141 A144 R147 R151 Y155 K156 Y162 K170 A172 K174 K175 P0AG55 24844575 SRVAKAPVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK 4csu H 5.50 BS01 NUC B 1 A10 N11 L12 K22 A23 G24 Y25 R27 N28 F29 P32 Q33 E70 I72 N73 L75 D101 A102 T104 A105 A106 G107 V108 E109 V110 A111 A10 N11 L12 K22 A23 G24 Y25 R27 N28 F29 P32 Q33 E70 I72 N73 L75 D101 A102 T104 A105 A106 G107 V108 E109 V110 A111 P0A7R1 24844575 MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE 4csu I 5.50 BS01 NUC B 1 P74 A75 A76 K80 G88 S89 G90 K91 P92 N93 K94 K112 D115 M116 T117 G118 A119 D120 A123 R126 S127 I128 G130 T131 R133 S134 M135 P2 A3 A4 K8 G16 S17 G18 K19 P20 N21 K22 K40 D43 M44 T45 G46 A47 D48 A51 R54 S55 I56 G58 T59 R61 S62 M63 P0A7J7 24844575 PPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED 4csu J 5.50 BS01 NUC B 1 K2 T3 F4 K7 E9 W15 L25 G26 R27 T30 E31 R34 R37 K39 V48 Y53 V64 T65 N67 K68 K72 Y75 H76 H77 T78 H80 G82 G83 I84 K85 Q86 E90 E91 R95 R96 I103 A104 G107 M108 L109 P110 K111 P113 L114 R116 R120 K123 H132 A133 A134 Q135 Q136 K2 T3 F4 K7 E9 W15 L25 G26 R27 T30 E31 R34 R37 K39 V48 Y53 V64 T65 N67 K68 K72 Y75 H76 H77 T78 H80 G82 G83 I84 K85 Q86 E90 E91 R95 R96 I103 A104 G107 M108 L109 P110 K111 P113 L114 R116 R120 K123 H132 A133 A134 Q135 Q136 P0AA10 24844575 MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI 4csu K 5.50 BS01 NUC B 1 M1 I2 E4 Q5 T6 M7 R18 I22 K23 L25 G27 S28 H29 R30 R31 Y32 K40 T42 K54 G55 K66 K67 R70 G74 V76 R78 N82 M1 I2 E4 Q5 T6 M7 R18 I22 K23 L25 G27 S28 H29 R30 R31 Y32 K40 T42 K54 G55 K66 K67 R70 G74 V76 R78 N82 P0ADY3 24844575 MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPE 4csu L 5.50 BS01 NUC B 1 L3 N4 L6 E10 G11 S12 K13 K14 A15 G16 K17 R18 L19 G20 R21 G22 I23 G24 S25 L27 G28 K29 T30 G31 G32 R33 G34 H35 K36 G37 Q38 K39 R41 S42 G43 G44 V46 R47 R48 G49 F50 G52 G53 Q54 M55 L57 Y58 R59 R60 L61 P62 K63 F64 G65 F66 S68 R69 K70 A71 E76 R78 D81 K84 N99 I103 Q104 K109 I111 L112 A113 R126 V127 T128 K129 G130 R132 L2 N3 L5 E9 G10 S11 K12 K13 A14 G15 K16 R17 L18 G19 R20 G21 I22 G23 S24 L26 G27 K28 T29 G30 G31 R32 G33 H34 K35 G36 Q37 K38 R40 S41 G42 G43 V45 R46 R47 G48 F49 G51 G52 Q53 M54 L56 Y57 R58 R59 L60 P61 K62 F63 G64 F65 S67 R68 K69 A70 E75 R77 D80 K83 N98 I102 Q103 K108 I110 L111 A112 R125 V126 T127 K128 G129 R131 P02413 24844575 RLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEIRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE 4csu M 5.50 BS02 NUC B 1 L2 Q3 P4 K5 R6 K8 F9 R10 K11 M12 H13 K14 G15 R16 N17 R18 Q22 G23 T24 D25 S27 F28 R40 R44 A48 R51 R55 K62 W64 R66 V67 F68 D70 T74 E75 K76 L78 V80 R81 M82 G83 K84 G85 K86 G87 L95 K100 K118 L119 A122 K123 P125 K127 L2 Q3 P4 K5 R6 K8 F9 R10 K11 M12 H13 K14 G15 R16 N17 R18 Q22 G23 T24 D25 S27 F28 R40 R44 A48 R51 R55 K62 W64 R66 V67 F68 D70 T74 E75 K76 L78 V80 R81 M82 G83 K84 G85 K86 G87 L95 K100 K118 L119 A122 K123 P125 K127 P0ADY7 24844575 MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM 4csu N 5.50 BS01 NUC B 1 M1 R2 H3 R4 K5 G7 R8 Q9 L10 N11 R12 N13 S14 H16 R17 R22 N23 M24 S27 R30 H31 I34 K35 T36 K40 K42 R45 R46 E49 P50 T53 V60 A61 R63 R64 L65 F67 A68 R71 N73 R90 A91 G92 G93 T95 R96 L98 K99 R103 A104 G105 D106 A108 M1 R2 H3 R4 K5 G7 R8 Q9 L10 N11 R12 N13 S14 H16 R17 R22 N23 M24 S27 R30 H31 I34 K35 T36 K40 K42 R45 R46 E49 P50 T53 V60 A61 R63 R64 L65 F67 A68 R71 N73 R90 A91 G92 G93 T95 R96 L98 K99 R103 A104 G105 D106 A108 P0AG44 24844575 MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSE 4csu O 5.50 BS01 NUC A 1 K3 K4 R7 R15 H29 R30 T31 P32 R33 H34 Y36 Q38 G44 S45 E46 V47 V54 E55 K56 K63 Y64 N67 K68 F97 Q98 H100 G101 R102 V103 K2 K3 R6 R14 H28 R29 T30 P31 R32 H33 Y35 Q37 G43 S44 E45 V46 V53 E54 K55 K62 Y63 N66 K67 F96 Q97 H99 G100 R101 V102 P0C018 24844575 DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF 4csu O 5.50 BS02 NUC B 1 R9 R10 T12 R13 R16 F92 R94 Q98 Y99 R111 F117 R8 R9 T11 R12 R15 F91 R93 Q97 Y98 R110 F116 P0C018 24844575 DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF 4csu P 5.50 BS01 NUC B 1 S1 K5 R20 I49 R50 N51 R52 H55 E70 V72 Q74 R92 K93 A94 K95 Y97 Y98 R100 R102 A106 R108 R112 L113 N114 S1 K5 R20 I49 R50 N51 R52 H55 E70 V72 Q74 R92 K93 A94 K95 Y97 Y98 R100 R102 A106 R108 R112 L113 N114 P0A7K6 24844575 SNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN 4csu Q 5.50 BS01 NUC B 1 A1 R2 V3 K4 R5 G6 V7 I8 R10 R12 K14 K15 K18 K21 G22 Y23 Y24 G25 A26 R27 R29 V30 Y31 R32 V33 F35 Q36 I39 K40 Y44 Y46 R47 D48 R49 R50 R52 K53 R54 F56 R57 Q58 W60 I61 A62 N65 R69 S74 Y75 S76 K77 I79 N80 K83 I89 R91 K92 I93 A1 R2 V3 K4 R5 G6 V7 I8 R10 R12 K14 K15 K18 K21 G22 Y23 Y24 G25 A26 R27 R29 V30 Y31 R32 V33 F35 Q36 I39 K40 Y44 Y46 R47 D48 R49 R50 R52 K53 R54 F56 R57 Q58 W60 I61 A62 N65 R69 S74 Y75 S76 K77 I79 N80 K83 I89 R91 K92 I93 P0A7L3 24844575 ARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA 4csu R 5.50 BS01 NUC B 1 G9 K10 Q11 E23 K24 L25 K71 K73 K76 R78 R79 R80 K81 H82 Y83 R84 K85 Q86 G88 H89 R90 Q91 W92 G9 K10 Q11 E23 K24 L25 K71 K73 K76 R78 R79 R80 K81 H82 Y83 R84 K85 Q86 G88 H89 R90 Q91 W92 P0AG48 24844575 MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA 4csu S 5.50 BS01 NUC B 1 T3 I4 A5 K6 H7 R8 R11 S12 S13 Q15 K16 R18 R25 K41 K42 K49 S53 A56 N57 H60 N61 K73 F75 D77 E78 M82 R84 M86 P87 R88 A89 K90 G91 R92 D94 R95 L97 K98 R99 H102 T3 I4 A5 K6 H7 R8 R11 S12 S13 Q15 K16 R18 R25 K41 K42 K49 S53 A56 N57 H60 N61 K73 F75 D77 E78 M82 R84 M86 P87 R88 A89 K90 G91 R92 D94 R95 L97 K98 R99 H102 P61175 24844575 METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR 4csu T 5.50 BS01 NUC B 1 M1 I2 R3 E4 H15 E18 K19 A20 S21 M24 T29 A38 T39 K40 V57 V58 N59 T60 L61 V62 K64 K66 K68 R69 Q72 R73 I74 G75 R76 R77 S78 K82 Y84 M1 I2 R3 E4 H15 E18 K19 A20 S21 M24 T29 A38 T39 K40 V57 V58 N59 T60 L61 V62 K64 K66 K68 R69 Q72 R73 I74 G75 R76 R77 S78 K82 Y84 P0ADZ0 24844575 MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNL 4csu U 5.50 BS01 NUC B 1 A2 K3 I4 R6 L13 T14 G15 K16 K18 N26 V27 V41 K42 K43 H44 Q45 K46 P47 G56 I57 Q65 S67 N68 V69 K78 A79 D80 R81 G83 R85 K90 K91 K96 A1 K2 I3 R4 L10 T11 G12 K13 K15 N23 V24 V38 K39 K40 H41 Q42 K43 P44 G53 I54 Q62 S64 N65 V66 K75 A76 D77 R78 G80 R82 K87 K88 K93 P60624 24844575 AKIRDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETI 4csu W 5.50 BS01 NUC A 1 R9 Q12 G13 K14 S17 R18 R19 R21 P27 I29 Y31 K34 Q75 Q78 Q87 H88 R9 Q12 G13 K14 S17 R18 R19 R21 P27 I29 Y31 K34 Q75 Q78 Q87 H88 P68919 24844575 MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA 4csu Y 5.50 BS01 NUC B 1 G6 G7 T9 R10 N11 G12 R13 D14 S15 E16 A17 R19 L20 K23 R24 F25 S29 V30 L31 A32 I35 R38 R40 G41 T42 F44 V50 G53 R54 D55 H56 F59 K65 V66 K67 F68 R76 K77 G1 G2 T4 R5 N6 G7 R8 D9 S10 E11 A12 R14 L15 K18 R19 F20 S24 V25 L26 A27 I30 R33 R35 G36 T37 F39 V45 G48 R49 D50 H51 F54 K60 V61 K62 F63 R71 K72 P0A7L8 24844575 GGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE 4ct0 A 2.45 BS01 ZN A 1 C414 H473 C404 H463 P97784 24855952 VNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVAANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRG 4ct0 B 2.45 BS01 ZN A 1 C1210 C1213 C92 C95 O54943 24855952 AGLEVLFQGPDSMYVLQDPIWLLMANTDDSIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPRFTEGQRRELREVHPWVHTGGLPTAIDVTGCVYCE 4cym A 2.80 BS01 MG A 1 T39 T57 T18 T36 3.6.5.2 Q13637 24856514 REHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGLERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQS 4czw A 2.60 BS01 ZN A 1 H525 C530 C535 C538 H70 C75 C80 C83 3.1.13.4 P0C581 DHWSLRPEAPPEYRICEIKYSKFGVDDFDFGFFNNTPYPGLENNITNSYANSLLQVMHYTPLLRNMALQHAATACLADPCLLCELGYVFDMLQKGEGPSCHATNMLRALNHTSNASVSGVLEDIAKDKNPSTLVKNLTMFLFDKISQDYKGTPPISTELERTLFKLNQPPNPLDLVKRLLETDARYQIKCMHCQHVSPRTATTFVNKLCYPAQRITFSQVLKAGLENEAVNKGYCTKCQRYQNLDQRKIIFNIPAVLALCTEITTAEHRKLWSTPGWLPEEIGIIVDQGHVYCYEGDDLKLHLNRHNITVYSLVGTVVNVETKSPQKSHLVATVNVGRAEPESKDQDRWHLFNDFSVRGISKVEALTFNAAWKMPVVVMFQVKAANHRFNMDWKTRLDTSVLFRDNNPHALKTYELLDRETEIPGPDTVIAIDTEFIRLKISHAIARASVVRGQGSREGVAFIDDYIHIKETIVDYLTEWSGITPTDLDPINSQRNLVSPKTAYKKLWVLVNLGCKFLGHGLSQDFRVINIQVPRNQVIDTSIIFMKPPSQRKISLAFLAWYLLKEDIQQNTHDSIEDAQTALKLYRKYEEFMANGSFHDVLEALYKKG 4czw A 2.60 BS02 ZN A 2 C645 C648 C700 C703 C190 C193 C235 C238 3.1.13.4 P0C581 DHWSLRPEAPPEYRICEIKYSKFGVDDFDFGFFNNTPYPGLENNITNSYANSLLQVMHYTPLLRNMALQHAATACLADPCLLCELGYVFDMLQKGEGPSCHATNMLRALNHTSNASVSGVLEDIAKDKNPSTLVKNLTMFLFDKISQDYKGTPPISTELERTLFKLNQPPNPLDLVKRLLETDARYQIKCMHCQHVSPRTATTFVNKLCYPAQRITFSQVLKAGLENEAVNKGYCTKCQRYQNLDQRKIIFNIPAVLALCTEITTAEHRKLWSTPGWLPEEIGIIVDQGHVYCYEGDDLKLHLNRHNITVYSLVGTVVNVETKSPQKSHLVATVNVGRAEPESKDQDRWHLFNDFSVRGISKVEALTFNAAWKMPVVVMFQVKAANHRFNMDWKTRLDTSVLFRDNNPHALKTYELLDRETEIPGPDTVIAIDTEFIRLKISHAIARASVVRGQGSREGVAFIDDYIHIKETIVDYLTEWSGITPTDLDPINSQRNLVSPKTAYKKLWVLVNLGCKFLGHGLSQDFRVINIQVPRNQVIDTSIIFMKPPSQRKISLAFLAWYLLKEDIQQNTHDSIEDAQTALKLYRKYEEFMANGSFHDVLEALYKKG 4czy B 3.40 BS01 ANP B 1 D271 N277 S278 T279 M287 A300 R302 D352 F353 H354 S357 E358 T359 K413 I415 D38 N44 S45 T46 M54 A67 R69 D119 F120 H121 S124 E125 T126 K174 I176 Q7SDP4 IPKDRRENLQKKLFHMQQLLPNSGLPNLDRWHSLFPLDTKATRNSTCFGYPSWMYKAQNNKNGRHFALRRIEGYRLTNEKAILNVTKEWKKIINANIVTVHEAFTTEFFGDSSLIFVYDFHPLSETLYDHHFPPNRNTNKIPENLLWSYVCQIANALLAIHNAKLAARCLELSKIIWENNRIRLAACSILDVLHHDSPNRKTIEELQQEDFVKFGRIILALATNTPTLNFNNIDAALATIVPRYSTQLRGVLEWLIKPSAPGETKTVETLLGGITTHLANFANFVMQESDEKEFHLMRELENGRIARLMFKLSVVNERGDSHNWSETGERLLLKLFRDYVFHQVDADGKARLDTNHYLNCLSKLDASSEEQILLTSRDNATVFVVSYRSIRQMLDRAYGELGK 4czy D 3.40 BS01 ANP D 1 L270 D271 N277 T279 M287 A300 R302 D352 F353 H354 S357 E358 T359 S412 K413 I415 L37 D38 N44 T46 M54 A67 R69 D119 F120 H121 S124 E125 T126 S173 K174 I176 Q7SDP4 IPKDRRENLQKKLFHMQQLLPNSGLPNLDRWHSLFPLDTKATRNSTCFGYPSWMYKAQNNKNGRHFALRRIEGYRLTNEKAILNVTKEWKKIINANIVTVHEAFTTEFFGDSSLIFVYDFHPLSETLYDHHFPPNNNTNKIPENLLWSYVCQIANALLAIHNAKLAARCLELSKIIWENNRIRLAACSILDVLHHDSPNRKTIEELQQEDFVKFGRIILALATNTPTLNFNNIDAALATIVPRYSTQLRGVLEWLIKPSAPGETKTVETLLGGITTHLANFANFVMQESDEKEFHLMRELENGRIARLMFKLSVVNERCGVHNWSETGERLLLKLFRDYVFHQVDADGKARLDTNHYLNCLSKLDASSEEQILLTSRDNATVFVVSYRSIRQMLDRAYGELGK 4czy D 3.40 BS02 MG D 1 D271 R276 S285 D38 R43 S52 Q7SDP4 IPKDRRENLQKKLFHMQQLLPNSGLPNLDRWHSLFPLDTKATRNSTCFGYPSWMYKAQNNKNGRHFALRRIEGYRLTNEKAILNVTKEWKKIINANIVTVHEAFTTEFFGDSSLIFVYDFHPLSETLYDHHFPPNNNTNKIPENLLWSYVCQIANALLAIHNAKLAARCLELSKIIWENNRIRLAACSILDVLHHDSPNRKTIEELQQEDFVKFGRIILALATNTPTLNFNNIDAALATIVPRYSTQLRGVLEWLIKPSAPGETKTVETLLGGITTHLANFANFVMQESDEKEFHLMRELENGRIARLMFKLSVVNERCGVHNWSETGERLLLKLFRDYVFHQVDADGKARLDTNHYLNCLSKLDASSEEQILLTSRDNATVFVVSYRSIRQMLDRAYGELGK 4d2l A 2.90 BS01 III B 1 V100 D103 Y104 D107 M111 M114 K118 F120 F125 E128 L139 G140 V141 A144 V52 D55 Y56 D59 M63 M66 K70 F72 F77 E80 L91 G92 V93 A96 O57173 24850748 TNILDYLSTERDHVMMAVRYYMSKQRLDDLYRQLPTKTRSYIDIINIYCDKVSNDYNRDMNIMYDMASTKSFTVYDFNNEVNTIMLDNKGLGVRLATISFITELGRRCMNPVKTIKMFTLLSHTICDDCFVDYITDIS 4d2m A 2.10 BS01 III B 1 Y96 V100 Y104 D107 M108 M111 M114 A115 T117 S119 F120 T121 D124 F125 E128 I132 N136 G138 L139 G140 V141 L143 A144 T145 F148 Y46 V50 Y54 D57 M58 M61 M64 A65 T67 S69 F70 T71 D74 F75 E78 I82 N86 G88 L89 G90 V91 L93 A94 T95 F98 O57173 24850748 ILDYLSTERDHVMMAVRYYMSKQRLDDLYRQLPTKTRSYIDIINIYCDKVSNDYNRDMNIMYDMASTKSFTVYDFNNEVNTIMLDNKGLGVRLATISFITELGRRCMNPVKTIKMFTLLSHTICDDCFVDYITDIS 4d2m C 2.10 BS01 III D 1 Y96 V100 Y104 D107 M111 M114 A115 S119 F120 T121 D124 F125 E128 I132 N136 G138 L139 G140 V141 L143 A144 T145 F148 Y46 V50 Y54 D57 M61 M64 A65 S69 F70 T71 D74 F75 E78 I82 N86 G88 L89 G90 V91 L93 A94 T95 F98 O57173 24850748 ILDYLSTERDHVMMAVRYYMSKQRLDDLYRQLPTKTRSYIDIINIYCDKVSNDYNRDMNIMYDMASTKSFTVYDFNNEVNTIMLDNKGLGVRLATISFITELGRRCMNPVKTIKMFTLLSHTICDDCFVDYITDIS 4kvb B 4.20 BS01 NUC A 1 R21 K22 P26 K27 R96 G99 G100 T103 N104 R111 R144 Y148 I172 R175 K179 R16 K17 P21 K22 R91 G94 G95 T98 N99 R106 R139 Y143 I167 R170 K174 P62662 TVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4kvb C 4.20 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 R127 S154 R156 E161 Q162 A163 R172 V173 P174 L175 H176 T177 L178 R179 F186 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 K25 R126 S153 R155 E160 Q161 A162 R171 V172 P173 L174 H175 T176 L177 R178 F185 T191 Y192 G193 V194 G196 K198 P62663 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4kvb D 4.20 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 L21 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 A55 R59 K61 Q62 R66 E72 R73 Q74 N77 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 S137 Y138 R141 L155 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 L20 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 A54 R58 K60 Q61 R65 E71 R72 Q73 N76 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 S136 Y137 R140 L154 E204 S207 R208 P62664 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4kvb E 4.20 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 G23 R24 R25 R27 F45 P49 K57 Y60 Y61 A86 A94 A95 T98 I101 A102 R107 L119 T120 K121 E122 L123 S125 R126 N127 I129 N130 R10 T12 A13 R14 M15 Q16 A17 G18 G19 R20 R21 R23 F41 P45 K53 Y56 Y57 A82 A90 A91 T94 I97 A98 R103 L115 T116 K117 E118 L119 S121 R122 N123 I125 N126 P62665 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4kvb G 4.20 BS01 NUC A 1 A2 R3 R4 R5 R6 A7 R10 L12 N28 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 G81 G82 Y85 R94 R95 S98 R102 N109 R114 R115 A116 R119 A1 R2 R3 R4 R5 A6 R9 L11 N27 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 G80 G81 Y84 R93 R94 S97 R101 N108 R113 R114 A115 R118 P62667 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4kvb H 4.20 BS01 NUC A 1 M1 L2 T3 D8 T11 R12 R14 N15 V19 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 R102 R105 S113 T114 S115 G130 E132 M1 L2 T3 D8 T11 R12 R14 N15 V19 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 R102 R105 S113 T114 S115 G130 E132 P62668 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4kvb I 4.20 BS01 NUC A 1 Q3 Y5 R9 R10 K11 E12 V14 R16 R20 Y36 Q38 R42 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 H117 K118 R120 R121 A122 Q124 Y125 S126 K127 Q2 Y4 R8 R9 K10 E11 V13 R15 R19 Y35 Q37 R41 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 H116 K117 R119 R120 A121 Q123 Y124 S125 K126 P62669 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGRFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4kvb J 4.20 BS01 NUC A 1 R5 K7 R9 H13 S35 G36 P37 P39 L40 P41 T42 R43 V44 R45 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 E61 H62 H68 R70 D73 K99 R3 K5 R7 H11 S33 G34 P35 P37 L38 P39 T40 R41 V42 R43 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 E59 H60 H66 R68 D71 K97 P62653 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4kvb K 4.20 BS01 NUC A 1 Y20 N26 N27 I29 T31 T33 G37 P39 I40 W42 S44 G46 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 K122 K123 K124 Y10 N16 N17 I19 T21 T23 G27 P29 I30 W32 S34 G36 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 K112 K113 K114 P62654 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 4kvb L 4.20 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 K17 R19 K20 K21 K23 V24 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 L52 R53 K54 T61 Y69 P71 G72 E73 R86 G87 G88 K91 D92 R97 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 K13 R15 K16 K17 K19 V20 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 L48 R49 K50 T57 Y65 P67 G68 E69 R82 G83 G84 K87 D88 R93 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 P61941 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4kvb M 4.20 BS01 NUC A 1 R14 V17 Y23 G24 I25 G26 A28 R29 R44 L70 N77 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 V117 R125 K126 R13 V16 Y22 G23 I24 G25 A27 R28 R43 L69 N76 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 V116 R124 K125 P62655 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAPRK 4kvb N 4.20 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K15 F16 K17 V18 R19 Y21 T22 R23 C27 R29 R31 S32 V33 Y34 R35 R41 I42 R45 E46 R57 K58 S60 W61 A1 R2 K3 A4 L5 E7 K14 F15 K16 V17 R18 Y20 T21 R22 C26 R28 R30 S31 V32 Y33 R34 R40 I41 R44 E45 R56 K57 S59 W60 P62656 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4kvb O 4.20 BS01 NUC A 1 P2 K5 K8 D21 T22 G23 S24 T25 Q28 L31 R35 R38 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 M58 G61 R64 R65 R68 Y69 R72 P1 K4 K7 D20 T21 G22 S23 T24 Q27 L30 R34 R37 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 M57 G60 R63 R64 R67 Y68 R71 P62657 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4kvb P 4.20 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 E83 M1 V2 K3 R5 L6 R8 F9 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 E83 P62238 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4kvb S 4.20 BS01 NUC A 1 P2 R3 S4 K6 F10 H14 W34 R36 R37 Y52 G54 K55 K70 G72 E73 T77 R78 T79 Y80 R81 P1 R2 S3 K5 F9 H13 W33 R35 R36 Y51 G53 K54 K69 G71 E72 T76 R77 T78 Y79 R80 P62660 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4kvb T 4.20 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 N26 K27 K29 S31 A32 K34 T35 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 R89 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 N19 K20 K22 S24 A25 K27 T28 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 R82 G94 G95 G96 L97 S98 P62661 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAVQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4kyu A 1.70 BS01 GDP A 1 N13 V14 G15 K16 S17 T18 N119 K120 D122 S145 G146 T147 N12 V13 G14 K15 S16 T17 N108 K109 D111 S134 G135 T136 P50743 GKPVVAIVGRPNVGKSTIFNRIAGERIRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLAQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHF 4kyu A 1.70 BS02 MG A 1 S17 N21 S16 N20 P50743 GKPVVAIVGRPNVGKSTIFNRIAGERIRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLAQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHF 4kyu B 1.70 BS02 MG B 1 S17 D57 S15 D37 P50743 KPVVAIVGRPNVGKSTIFNRIAIYSSAEWNYDFNLIDTGGIDIGDEPFLAQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHF 4kyw A 2.35 BS01 NUC C 1 N16 S17 Q18 A20 R21 N48 P50 V51 D53 E64 S67 K68 K69 N77 D78 G79 A80 T83 Y101 R135 W138 N16 S17 Q18 A20 R21 N48 P50 V51 D53 E64 S67 K68 K69 N77 D78 G79 A80 T83 Y101 R135 W138 3.1.21.4 P0A459 MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYTKNFEVNNFLVLPKQFVTPKSIIQRKPLAPTANRAGWIGCNIDLSQVPSKGRIFLVQDGQVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL 4kyw A 2.35 BS02 NUC D 1 Y13 K14 S15 Q18 R21 N47 N48 R126 L129 A130 A133 N134 R135 N142 Y13 K14 S15 Q18 R21 N47 N48 R126 L129 A130 A133 N134 R135 N142 3.1.21.4 P0A459 MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYTKNFEVNNFLVLPKQFVTPKSIIQRKPLAPTANRAGWIGCNIDLSQVPSKGRIFLVQDGQVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL 4kyw A 2.35 BS03 NUC E 1 R179 G187 W188 K222 N223 N224 H225 E228 K229 Q232 R179 G187 W188 K222 N223 N224 H225 E228 K229 Q232 3.1.21.4 P0A459 MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYTKNFEVNNFLVLPKQFVTPKSIIQRKPLAPTANRAGWIGCNIDLSQVPSKGRIFLVQDGQVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL 4kyw A 2.35 BS04 NUC F 1 L206 E228 R231 Q232 Q235 R238 F245 R248 G249 Y251 L206 E228 R231 Q232 Q235 R238 F245 R248 G249 Y251 3.1.21.4 P0A459 MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYTKNFEVNNFLVLPKQFVTPKSIIQRKPLAPTANRAGWIGCNIDLSQVPSKGRIFLVQDGQVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL 4kyw A 2.35 BS06 CA A 1 D53 E64 L65 K66 D53 E64 L65 K66 3.1.21.4 P0A459 MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYTKNFEVNNFLVLPKQFVTPKSIIQRKPLAPTANRAGWIGCNIDLSQVPSKGRIFLVQDGQVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL 4kzn A 1.71 BS01 FUC A 1 Y39 M94 S95 Y27 M82 S83 P15692 EVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPK 4l20 A 1.68 BS01 HEM A 1 W14 E19 R20 V44 G48 F49 D52 P54 G57 C60 V61 F64 Q65 K75 N78 I80 T87 Y89 W12 E17 R18 V42 G46 F47 D50 P52 G55 C58 V59 F62 Q63 K73 N76 I78 T85 Y87 O76745 PPAQLSVHTVSWNSGHERVPTNLEELLGLNSGETPDVIAVAVQGFGFQTDKPQQGPACVKNFQSLLTSKGYTKLKNTITETMGLTVYCLEKHLDQNTLKNETIIVTVDDQKKSGGIVTSFTIYNKRFSFTTSRMSDEDVTSTNTKYAYDTRLDYSKKDDPSDFLFWIGDLNVRVETNATHAKSLVDQNNIDGLMAFDQLKKAKEQKLFDGWTEPQVTFKPTYKFKPNTDEYDLSATPSWTDRALYKSGTGKTIQPLSYNSLTNYKQTEHRPVLAKFRVTL 4l21 A 1.65 BS01 HEM A 1 S16 E19 A21 L28 V44 F49 D52 Q56 G57 C60 V61 V64 K75 N78 I80 T87 Y89 S14 E17 A19 L26 V42 F47 D50 Q54 G55 C58 V59 V62 K73 N76 I78 T85 Y87 O76745 PPAQLSVHTVSWNSGHERAPTNLEELLGLNSGETPDVIAVAVQGFGFQTDKPQQGPACVKNVQSLLTSKGYTKLKNTITETMGLTVYCLEKHLDQNTLKNETIIVTVDDQKKSGGIVTSFTIYNKRFSFTTSRMSDEDVTSTNTKYAYDTRLDYSKKDDPSDFLFWIGDLNVRVETNATHAKSLVDQNNIDGLMAFDQLKKAKEQKLFDGWTEPQVTFKPTYKFKPNTDEYDLSATPSWTDRALYKSGTGKTIQPLSYNSLTNYKQTEHRPVLAKFRVTL 4l21 A 1.65 BS02 NO A 1 V44 I80 V42 I78 O76745 PPAQLSVHTVSWNSGHERAPTNLEELLGLNSGETPDVIAVAVQGFGFQTDKPQQGPACVKNVQSLLTSKGYTKLKNTITETMGLTVYCLEKHLDQNTLKNETIIVTVDDQKKSGGIVTSFTIYNKRFSFTTSRMSDEDVTSTNTKYAYDTRLDYSKKDDPSDFLFWIGDLNVRVETNATHAKSLVDQNNIDGLMAFDQLKKAKEQKLFDGWTEPQVTFKPTYKFKPNTDEYDLSATPSWTDRALYKSGTGKTIQPLSYNSLTNYKQTEHRPVLAKFRVTL 4ldj A 1.15 BS01 GDP A 1 G13 V14 G15 K16 S17 A18 F28 D30 E31 N116 K117 D119 L120 S145 A146 K147 G14 V15 G16 K17 S18 A19 F29 D31 E32 N117 K118 D120 L121 S146 A147 K148 P01116 GMTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK 4lma A 2.30 BS01 PLP A 1 V45 K46 N77 G181 T182 G183 G184 T185 G225 I226 S269 P296 S297 V45 K46 N77 G181 T182 G183 G184 T185 G225 I226 S269 P296 S297 2.5.1.47 A8YBS4 24275508 MRIAHDVTELVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIGTHMINSAEKAGLINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTPGSQGMKGAILRAQQIVDSIPGAYMLQQFRNPSNPEIHRLTTAEEIWQDTEGQVDFIVAGVGTGGTITGVAEVIKSRKPSFQVVAVEPFNSPVISGGNPGPHKIQGIGAGFIPEVLRTDLIDEVITVSDEEAFQFGRRLAKEEGLLSGISSGANLCAAIQLAQRPENEGKLIVVIQPSFGERYLSTLMFQNIEERELTL 4lma B 2.30 BS01 PLP B 1 V45 K46 N77 G179 G181 T182 G183 T185 G225 I226 S269 P296 S297 V45 K46 N77 G179 G181 T182 G183 T185 G225 I226 S269 P296 S297 2.5.1.47 A8YBS4 24275508 MRIAHDVTELVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIGTHMINSAEKAGLINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTPGSQGMKGAILRAQQIVDSIPGAYMLQQFRNPSNPEIHRLTTAEEIWQDTEGQVDFIVAGVGTGGTITGVAEVIKSRKPSFQVVAVEPFNSPVISGGNPGPHKIQGIGAGFIPEVLRTDLIDEVITVSDEEAFQFGRRLAKEEGLLSGISSGANLCAAIQLAQRPENEGKLIVVIQPSFGERYLSTLMFQNIE 4lmb A 1.91 BS01 CYS A 1 K46 T74 S75 N77 T78 M125 Q147 F148 G225 K46 T74 S75 N77 T78 M125 Q147 F148 G225 2.5.1.47 A8YBP8 24275508 MLIARDITQLVGRTPLVQLNRIPVAEGVKARIVVKLESMNPAASVKDRIGVSMVEDAEAAGLIHPDKTILVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTPGSQGMEGAITRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGVGTGGTITGIAETIKPRRPQFQAIAVEPSNSPVLSGGQPGPHKIQGIGAGFIPAIFRPELIDEVIIVDDTEAFAYARRLARQEGLLSGISAGAALWAAIQVGKRPENEDKLIVMIQPSFGERYLSTALFKD 4lmb A 1.91 BS02 CYS A 2 S75 M101 M125 F148 I223 Q224 G225 I226 A228 S75 M101 M125 F148 I223 Q224 G225 I226 A228 2.5.1.47 A8YBP8 24275508 MLIARDITQLVGRTPLVQLNRIPVAEGVKARIVVKLESMNPAASVKDRIGVSMVEDAEAAGLIHPDKTILVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTPGSQGMEGAITRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGVGTGGTITGIAETIKPRRPQFQAIAVEPSNSPVLSGGQPGPHKIQGIGAGFIPAIFRPELIDEVIIVDDTEAFAYARRLARQEGLLSGISAGAALWAAIQVGKRPENEDKLIVMIQPSFGERYLSTALFKD 4lmb A 1.91 BS03 PLP A 1 K46 N77 V180 G181 T182 G183 G184 T185 Q224 G225 I226 S269 P296 S297 Y302 K46 N77 V180 G181 T182 G183 G184 T185 Q224 G225 I226 S269 P296 S297 Y302 2.5.1.47 A8YBP8 24275508 MLIARDITQLVGRTPLVQLNRIPVAEGVKARIVVKLESMNPAASVKDRIGVSMVEDAEAAGLIHPDKTILVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTPGSQGMEGAITRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGVGTGGTITGIAETIKPRRPQFQAIAVEPSNSPVLSGGQPGPHKIQGIGAGFIPAIFRPELIDEVIIVDDTEAFAYARRLARQEGLLSGISAGAALWAAIQVGKRPENEDKLIVMIQPSFGERYLSTALFKD 4loy H 1.77 BS02 III L 1 E23 I24 G25 M26 P28 W29 S115 D116 H119 P120 C122 G133 Y134 K135 R137 N159 Y184A M201 K202 P204 N205 R206 W207 E8 I9 G10 M11 P13 W14 S112 D113 H116 P117 C119 G133 Y134 K135 R137 N157 Y183 M204 K205 P207 N210 R211 W212 3.4.21.5 P00734 24175584 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 4loy H 1.77 BS03 6XS H 1 H57 Y60A W60D L99 I174 D189 A190 V213 S214 W215 G216 E217 G219 C220 G226 F227 Y228 H43 Y47 W50 L96 I172 D192 A193 V218 S219 W220 G221 E222 G223 C224 G231 F232 Y233 3.4.21.5 P00734 24175584 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 4lus B 2.10 BS01 TCE B 1 T79 P81 K100 C126 E162 T77 P79 K98 C124 E155 5.1.1.1 Q180W0 KITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYGHGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKITMTVYSLETAQKINEIAKSLGEKACVHVKIDSGFQPNEESVQEIIELNKLEYIDLEGMFTHFATADEEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLRLNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTGKETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEVILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLL 4lut A 2.26 BS01 DCS A 1 K39 Y43 L85 H167 S208 R223 G225 I226 Y356 K37 Y41 L83 H158 S199 R214 G216 I217 Y347 5.1.1.1 Q180W0 KITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYGHGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKITMTVYSLETAQKINEIAKSLGEKACVHVKIDFQPNEESVQEIIELNKLEYIDLEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLRLNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTGKETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEVILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLL 4lut A 2.26 BS02 DCS B 1 Y268 Y287 C314 M315 Y259 Y278 C305 M306 5.1.1.1 Q180W0 KITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYGHGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKITMTVYSLETAQKINEIAKSLGEKACVHVKIDFQPNEESVQEIIELNKLEYIDLEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLRLNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTGKETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEVILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLL 4lut B 2.26 BS01 DCS A 1 Y287 C314 M315 Y267 C294 M295 5.1.1.1 Q180W0 KITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYGHGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKITMTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYIDLEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLRLNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEVILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLL 4lut B 2.26 BS02 DCS B 1 K39 Y43 L85 R137 H167 S208 R223 G225 I226 Y356 K37 Y41 L83 R135 H165 S206 R221 G223 I224 Y336 5.1.1.1 Q180W0 KITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYGHGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKITMTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYIDLEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLRLNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEVILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLL 4mr1 A 1.99 BS01 YPT A 1 R14 H15 T89 V92 N93 K96 R14 H15 T89 V92 N93 K96 3.2.1.17 P00698 24256441 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4mu8 A 1.45 BS01 HEM A 1 R13 C14 C17 H18 G29 P30 L32 I35 S40 G41 Y46 Y48 T49 N52 W59 M64 Y67 L68 T78 K79 M80 F82 L94 R17 C18 C21 H22 G33 P34 L36 I39 S44 G45 Y50 Y52 T53 N56 W63 M68 Y71 L72 T82 K83 M84 F86 L98 P00044 24760830 EFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGYSYTDANIKKNVLWDENNMSEYLTNPAKYIPGTKMAFGGLKKEKDRNDLITYLKKASE 4n58 A 1.86 BS01 FES A 1 Y36 S37 C38 R39 G41 A42 C43 C46 C75 Y35 S36 C37 R38 G40 A41 C42 C45 C74 24865810 ATYKVKDVTTGAEIEVPDDKYILDEFEKQGVNLPYSCRAGACSSCVALISSGEVDQSDGSFLSEKQEKKYILTCCSYPKSDCTIETGYEDKILEDFEIELAETGLEFFNLPRSGEILSGVTAPFEAFDHYLFGNGVERSININDVGFNINVSQIPPIMSLLNGKNVGRFDIGSDFVRNTALDGYSVAAYLGNITMRTEGVLNVKSDGTWQYEGVIRSYNDTYDANPSTHRGALGEWATGVLNNLSGTPYEIRIPGELKIKENGKKL 4n58 B 1.86 BS01 FES B 1 Y36 S37 C38 R39 G41 A42 C43 C46 L73 C75 Y34 S35 C36 R37 G39 A40 C41 C44 L71 C73 24865810 TYKVKDVTTGAEIEVPDDKYILDEFEKQGVNLPYSCRAGACSSCVALISSGEVDQSDGSFLSEKQEKKYILTCCSYPKSDCTIETGYEDKILEDFEIELAETGLEFFNLPRSGEILSGVTAPFEAFDHYLFGNGVERSININDVGFNINVSQIPPIMSLLNGKNVGRFDIGSDFVRNTALDGYSVAAYLGNITMRTEGVLNVKSDGTWQYEGVIRSYNDTYDANPSTHRGALGEWATGVLNNLSGTPYEIRIPGELKIKENGKKLE 4n59 A 2.30 BS01 FES A 1 S37 C38 R39 G41 A42 C43 C46 C75 S36 C37 R38 G40 A41 C42 C45 C74 24865810 ATYKVKDVTTGAEIEVPDDKYILDEFEKQGVNLPYSCRAGACSSCVALISSGEVDQSDGSFLSEKQEKKYILTCCSYPKSDCTIETGYEDKILEDFEIELAETGLEFFNDLKDSLPRSGEILSGVTAPFEAFDHYLFGNGVERSININDVGFNINVSQIPPIMSLLNGKNVGRFDIGSDFVRNTALDGYSVAAYLGNITMRTEGVLNVKSDGTWQYEGVIRSYNDTYDANPSTHRGALGEWSGTPYEIRIPGELKIKENGKK 4n73 A 1.87 BS01 COH A 1 H381 L382 V383 C384 P385 M386 F405 F409 V413 F443 L446 M447 F454 A479 G480 L482 L483 M486 H568 L572 F575 H1 L2 V3 C4 P5 M6 F25 F29 V33 F63 L66 M67 F74 A99 G100 L102 L103 M106 H188 L192 F195 Q14995 HLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVH 4nh2 A 2.30 BS01 P6L A 1 N72 F75 G76 N77 I78 N72 F75 G76 N77 I78 P69680 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 4nh2 B 2.30 BS01 P6L B 1 N72 F75 N79 N72 F75 N79 P69680 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLDPCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 4nh2 B 2.30 BS02 P6L C 1 M82 K84 M82 K84 P69680 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLDPCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 4nh2 C 2.30 BS01 P6L C 2 V61 L66 E70 N72 F75 G76 I78 T137 V61 L66 E70 N72 F75 G76 I78 T137 P69680 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLDDPCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 4nh2 C 2.30 BS02 P6L C 1 G282 G283 I286 V289 S335 S336 L337 G271 G272 I275 V278 S318 S319 L320 P69680 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLDDPCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 4nh2 D 2.30 BS01 P6L D 1 L66 N72 F75 I78 L138 L66 N72 F75 I78 L138 P69680 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLDPCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 4nh2 E 2.30 BS01 P6L E 1 Y62 L66 G71 N72 F75 N77 I78 T137 Y62 L66 G71 N72 F75 N77 I78 T137 P69680 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKDPCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 4nh2 F 2.30 BS01 P6L F 1 G71 N72 F75 G76 I78 T137 G71 N72 F75 G76 I78 T137 P69680 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 4nh2 F 2.30 BS02 P6L F 2 L81 K84 L81 K84 P69680 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 4nmm A 1.89 BS02 Y9Z A 1 C12 G13 V14 G15 K16 S17 A18 F28 V29 D30 P34 A59 N116 K117 D119 L120 S145 A146 C13 G14 V15 G16 K17 S18 A19 F29 V30 D31 P35 A60 N117 K118 D120 L121 S146 A147 3.6.5.2 P01116 GMTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK 4o3t A 2.99 BS01 III P 1 I505 H551 Y615 G616 Y619 T620 L629 R630 V631 A632 H633 S666 G667 P668 C669 D672 A698 I2 H48 Y112 G113 Y116 T117 L126 R127 V128 A129 H130 S163 G164 P165 C166 D169 A195 P14210 24859116 NIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILT 4o3u A 3.04 BS01 III P 1 H551 S611 C612 V614 Y619 T620 L629 R630 V631 A632 H633 L634 E662 S666 G667 P668 C669 D672 C697 A698 H48 S108 C109 V111 Y116 T117 L126 R127 V128 A129 H130 L131 E159 S163 G164 P165 C166 D169 C194 A195 P14210 24859116 NIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILT 4o5t A 2.90 BS01 XDA A 1 L42 A45 I87 M103 Y134 L161 C186 Q208 K238 A242 W257 H300 L40 A43 I82 M98 Y129 L156 C181 Q203 K233 A237 W252 H295 3.1.8.2 Q7SIG4 24847076 IPVIEPLFTKMTEDIPGATGPVFDKNGDFYVVASPLSEALINANSLAEARSDAGEILHIDLKTGKKTVICKPEVNGYGGSPIGCQCDRDANQLFVADMRLGLLVVQTDGTFEEIANKDSEGRCMQGCAYCAFDYEGNLWITAPAGGVAPADFTISLREKFGSIYCFTTDGQMIQVDTAFQCPAGIAVRHMNDGRPYQLIVAEQPTKKLWSYDIKGPANIENKKVWGHIPGTHKGGAAGMVFDEDNNLLVANWGSSHIEVFGPDGGQPKMRIRCPFEKPANLHFKPQTKTIFVTEHDNNAVWKFEWQRNGKKQYCETSKF 4o5t B 2.90 BS01 XDA B 1 L42 A45 N46 M103 A133 Y134 P148 I159 L161 C186 Q208 K238 W257 H300 L41 A44 N45 M99 A129 Y130 P144 I155 L157 C182 Q204 K234 W253 H296 3.1.8.2 Q7SIG4 24847076 EIPVIEPLFTKMTEDIPGATGPVFDKNGDFYVVASPLSEALINANSLAEAYSDAGEILHIDLKTGKKTVICKPEVNGYGGSPIGCQCDRDANQLFVADMRLGLLVVQTDGTFEEIANKDSEGRCMQGCAYCAFDYEGNLWITAPAGGVAPADFTISLREKFGSIYCFTTDGQMIQVDTAFQCPAGIAVRHMNDGRPYQLIVAEQPTKKLWSYDIKGPANIENKKVWGHIPGTHKGGAAGMVFDEDNNLLVANWGSSHIEVFGPDGGQPKMRIRCPFEKPANLHFKPQTKTIFVTEHDNNAVWKFEWQRNGKKQYCETSKFGIFGSL 4ols A 2.27 BS01 ZN A 1 H214 H324 C332 H26 H136 C144 D6QY02 TLKVSKNHINYTMDKRGKKPEGMVIHNDAGRSSGQQYENSLANAGYARYANGIAHYYGSEGYVWEAIDAKNQIAWHTGDGTGANSGNFRFAGIEVCQSMSASDAQFLKNEQAVFQFTAEKFKEWGLTPNRKTVRLHMEFVPTACPHRSMVLHTGFNPVTQGRPSQAIMNKLKDYFIKQIKNYMDK 4ols D 2.27 BS02 MG D 1 W263 H264 G266 N275 W75 H76 G78 N87 D6QY02 TLKVSKNHINYTMDKRGKKPEGMVIHNDAGRSSGQQYENSLANAGYARYANGIAHYYGSEGYVWEAIDAKNQIAWHTGDGTGANSGNFRFAGIEVCQSMSASDAQFLKNEQAVFQFTAEKFKEWGLTPNRKTVRLHMEFVPTACPHRSMVLHTGFNPVTQGRPSQAIMNKLKDYFIKQIKNYMDK 4ols D 2.27 BS03 FE D 1 G270 A271 N272 S273 G82 A83 N84 S85 D6QY02 TLKVSKNHINYTMDKRGKKPEGMVIHNDAGRSSGQQYENSLANAGYARYANGIAHYYGSEGYVWEAIDAKNQIAWHTGDGTGANSGNFRFAGIEVCQSMSASDAQFLKNEQAVFQFTAEKFKEWGLTPNRKTVRLHMEFVPTACPHRSMVLHTGFNPVTQGRPSQAIMNKLKDYFIKQIKNYMDK 4onj A 2.81 BS01 SFG A 1 N460 S461 F462 F488 S489 G490 I491 G493 E512 K513 N517 N538 D539 S565 L588 N203 S204 F205 F231 S232 G233 I234 G236 E255 K256 N260 N281 D282 S308 L313 2.1.1.- Q76KU6 24855943 RLPKPMIGFGVPTEPLPAMVRRTLPEQAVGPPFFYYENVALAPKGVWDTISRFLYDIEPEFVDSKYFCAAARKRGYIHNLPVENRFPLFPLAPRTIHEALPLSKKWWPSWDPRTKLNCLQTAIGSAQLTNRIRKAVEDFDGEPPMRVQKFVLDQCRKWNLVWVGRNKVAPLEPDEVEMLLGFPKNHTRGGGISRTDRYKSLGNSFQVDTVAYHLSVLKDLFPGGINVLSLFSGIGGGEVALYRLGIPLNTVVSVEKSEVNRDIVRSWWEQTNQRGNLIHFNDVQQLNGDRLEQLIESFGGFDLVIGGSPESSLFYDYVRILDLVKSIMSRH 4onj B 2.81 BS01 SFG B 1 N460 S461 F462 F488 G490 E512 K513 S514 N517 N538 S565 P566 L588 N204 S205 F206 F232 G234 E256 K257 S258 N261 N282 S309 P310 L316 2.1.1.- Q76KU6 24855943 IRLPKPMIGFGVPTEPLPAMVRRTLPEQAVGPPFFYYENVALAPKGVWDTISRFLYDIEPEFVDSKYFCAAARKRGYIHNLPVENRFPLFPLAPRTIHEALPLSKKWWPSWDPRTKLNCLQTAIGSAQLTNRIRKAVEDFDGEPPMRVQKFVLDQCRKWNLVWVGRNKVAPLEPDEVEMLLGFPKNHTRGGGISRTDRYKSLGNSFQVDTVAYHLSVLKDLFPGGINVLSLFSGIGGGEVALYRLGIPLNTVVSVEKSEVNRDIVRSWWEQTNQRGNLIHFNDVQQLNGDRLEQLIESFGGFDLVIGGSPCNESSLFYDYVRILDLVKSIMSR 4onq A 2.50 BS01 SFG A 1 N460 S461 F462 F488 S489 G490 I491 G493 E512 K513 N517 S565 L588 N203 S204 F205 F231 S232 G233 I234 G236 E255 K256 N260 S308 L311 2.1.1.- Q76KU6 24855943 RLPKPMIGFGVPTEPLPAMVRRTLPSQAVGPPFFYYENVALAPKGVWDTISSSLYDIEPEFVDSKYFCAAARKRGYIHNLPVENRFPLFPLAPRTIHEALPLSKKWWPSWDPRTKLNCLQTAIGSAQLTNRIRKAVEDFDGEPPMRVQKFVLDQCRKWNLVWVGRNKVAPLEPDEVEMLLGFPKNHTRGGGISRTDRYKSLGNSFQVDTVAYHLSVLKDLFPGGINVLSLFSGIGGGEVALYRLGIPLNTVVSVEKSEVNRDIVRSWWEQTNQRGNLIHFNDVQQLNGDRLEQLIESFGGFDLVIGGSPSLFSSYVRILDLVKSIMS 4onq B 2.50 BS01 SFG B 1 N460 S461 F462 F488 S489 G490 I491 G493 V511 E512 K513 N538 D539 V540 S565 L588 N196 S197 F198 F224 S225 G226 I227 G229 V247 E248 K249 N274 D275 V276 S301 L302 2.1.1.- Q76KU6 24855943 RLPKPMIGFGVPTERTLPSQAVGPPFFYYENVALAPKGVWDTISSSLYDIEPEFVDSKYFCAAARKRGYIHNLPVENRFPLFPLAPRTIHEALPLSKKWWPSWDPRTKLNCLQTAIGSAQLTNRIRKAVEDFDGEPPMRVQKFVLDQCRKWNLVWVGRNKVAPLEPDEVEMLLGFPKNHTRGGGISRTDRYKSLGNSFQVDTVAYHLSVLKDLFPGGINVLSLFSGIGGGEVALYRLGIPLNTVVSVEKSEVNRDIVRSWWEQTNQRGNLIHFNDVQQLNGDRLEQLIESFGGFDLVIGGSLFSSYVRILDLVKSIM 4oqp A 1.60 BS01 PED A 1 S115 W116 T118 T119 K141 T208 G210 D239 S242 K283 S58 W59 T61 T62 K84 T151 G153 D182 S185 K226 P39140 FEDLDALGSILEEKYGLLEAHVVFSPTPDYAGITHDLSRYGAEYMHETVKDGDIVGVSWGTTMYQIAQNMQPKQVKGVEVVQLKGGISHSRVNTYSAETIQLFAEAFQTMPRYLPLPVVFDNADVKRMVEKDRHIERIIEMGKQANIALFTVGTVRDEALLFRLGYFNEEEKALLKKQAVGDICSRFFDAKGNICSSAINDRTIGVELQDLRLKERSILVAGGSRKVSSIHGALTGKYANVLIIDQHTARALVN 4oqv A 1.23 BS02 2V6 A 1 M43 L46 Q47 P52 A55 A59 L68 V134 R136 Y356 L359 T360 P364 M10 L13 Q14 P19 A22 A26 L35 V101 R103 Y314 L317 T318 P322 1.3.5.2 Q02127 24801997 DERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHR 4or0 A 2.58 BS01 NPS A 1 N390 F402 R409 Y410 K413 V432 G433 C437 T448 L452 S488 N389 F401 R408 Y409 K412 V431 G432 C436 T447 L451 S487 P02769 24753230 THKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA 4or0 A 2.58 BS02 NPS A 2 F205 R208 A209 A212 L346 K350 S479 L480 V481 F204 R207 A208 A211 L345 K349 S478 L479 V480 P02769 24753230 THKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA 4or0 A 2.58 BS03 NPS A 3 R194 L197 S201 W213 R217 S343 L454 L480 R193 L196 S200 W212 R216 S342 L453 L479 P02769 24753230 THKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA 4or0 B 2.58 BS01 NPS B 1 N390 C391 F402 R409 Y410 T448 L452 S488 N389 C390 F401 R408 Y409 T447 L451 S487 P02769 24753230 THKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA 4or0 B 2.58 BS02 NPS B 2 R208 A209 A212 L326 L346 K350 S479 L480 V481 R207 A208 A211 L325 L345 K349 S478 L479 V480 P02769 24753230 THKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA 4or0 B 2.58 BS03 NPS B 3 R194 L197 R198 S201 A209 W213 R217 L346 L480 R193 L196 R197 S200 A208 W212 R216 L345 L479 P02769 24753230 THKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA 4ori A 1.50 BS02 2V6 A 1 M43 L46 Q47 P52 A55 A59 V134 R136 Y356 I360 P364 M8 L11 Q12 P17 A20 A24 V99 R101 Y315 I319 P323 1.3.5.2 Q63707 24801997 HFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR 4orm A 2.07 BS01 2V6 A 1 L172 G181 E182 C184 H185 F188 L197 F227 L240 I263 R265 L531 V532 M536 L12 G21 E22 C24 H25 F28 L37 F67 L80 I103 R105 L341 V342 M346 1.3.5.2 Q08210 24801997 YNPEFFLYDIFLKFCLKYIDGEICHDLFLLLGKYNILPYDTSNDSIYACTNIKHLDFINPFGVAAGFDKNGVCIDSILKLGFSFIEIGTITPRGQTGNAKPRIFRDVESRSIINSCGFNNMGCDKVTENLILFRKRQEEDKLLSKHIVGVSIGKNKDTVNIVDDLKYCINKIGRYADYIAINVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNIMNDEFLWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISNTTTQINDIKSFENKKGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLVFNGMKSAVQIKRELNHLLYQRGYYNLKEAIGRK 4ot2 A 2.42 BS01 NPS A 1 L386 N390 C391 F402 R409 Y410 K413 L429 C437 S448 L452 S488 L383 N387 C388 F399 R406 Y407 K410 L426 C434 S445 L449 S485 P35747 24753230 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGREDKEACFAEEGPKLVASSQLALA 4ot2 A 2.42 BS02 NPS A 2 R208 A212 L346 K350 S479 L480 R205 A209 L343 K347 S476 L477 P35747 24753230 KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGREDKEACFAEEGPKLVASSQLALA 4ouj A 1.46 BS01 LBT A 1 D264 Y266 G267 Q277 F279 N282 N286 D251 Y253 G254 Q264 F266 N269 N273 B1INP8 24631690 LNDKIVTISCKANTDLFFYQVPGNGNVSLFQQTRNYLERWRIIYDSNKAAYKIKSMNIYNTNLVLTWNAPTHNISAQQDSNADNQYWLLLKDIGNNSFIIASYKNPNLVLYADTVARNLKLSTLNNSSYIKFIIEDYVISDFKNFTCRISPILAGGKVVQQVSMTNLAVNLYIWNNDLNQKWTIIYNEEKAAYQFFNKILSNGVLTWIFSDGNTVRVSSSAQNNDAQYWLINPVSDRYTITNLRDKTKVLDLYGGQTADGTTIQVFNSNGGDNQKWNIRNP 4oxs A 2.80 BS02 2CV A 2 P193 W196 I200 P63 W66 I70 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDAM 4p19 A 3.25 BS01 HG A 1 C55 C364 L374 C49 C358 L368 O59010 24842876 YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGTLV 4p1a A 3.75 BS01 TL A 1 T308 I309 N310 S349 I350 G351 T352 A353 T302 I303 N304 S343 I344 G345 T346 A347 O59010 24842876 YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGTL 4p1a A 3.75 BS02 TL A 2 R276 A353 G354 V355 P356 D394 R397 T398 R270 A347 G348 V349 P350 D388 R391 T392 O59010 24842876 YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGTL 4p1a A 3.75 BS03 HG A 1 C55 C364 H368 C49 C358 H362 O59010 24842876 YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGTL 4p1a B 3.75 BS01 TL B 1 T308 I309 N310 M311 S349 I350 G351 T352 A353 T300 I301 N302 M303 S341 I342 G343 T344 A345 O59010 24842876 EYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE 4p1a C 3.75 BS02 TL C 2 R276 V355 P356 D394 R397 T398 R271 V350 P351 D389 R392 T393 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGT 4p2z A 3.08 BS01 2CV B 1 F142 K166 Y169 F12 K36 Y39 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTAFTVLNLAIGIIVDA 4p2z B 3.08 BS02 2CV B 2 F142 S165 K166 Y169 F12 S35 K36 Y39 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTAFTVLNLAIGIIVDA 4p2z C 3.08 BS01 2CV D 1 F142 S165 Y169 F13 S36 Y40 A0L5S6 24850863 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTAFTVLNLAIGIIVD 4p30 D 3.31 BS01 2CV C 3 S165 Y169 S36 Y40 A0L5S6 24850863 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTAFTVLNLAIGIIVD 4p6h A 4.08 BS02 TL A 1 S278 G306 A307 I309 N310 M311 N401 D405 S272 G300 A301 I303 N304 M305 N395 D399 O59010 24842876 YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE 4p9o A 2.89 BS02 2CV A 2 Y153 V197 F198 Y23 V67 F68 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDAM 4p9o B 2.89 BS01 2CV A 1 F142 S165 K166 Y169 F172 F12 S35 K36 Y39 F42 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4p9o B 2.89 BS02 2CV B 1 P193 N194 W196 I200 P63 N64 W66 I70 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4p9p A 2.91 BS01 2CV B 1 M189 P193 W196 M59 P63 W66 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDAM 4p9p C 2.91 BS01 2CV C 1 N194 W196 N65 W67 A0L5S6 24850863 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4p9p D 2.91 BS01 2CV C 1 F142 S165 K166 F172 F13 S36 K37 F43 A0L5S6 24850863 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4pa3 B 3.25 BS01 2CV A 1 F142 S165 K166 L168 Y169 F172 F12 S35 K36 L38 Y39 F42 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4pa3 D 3.25 BS02 2CV D 1 R186 P193 N194 W196 R57 P64 N65 W67 A0L5S6 24850863 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4pa4 C 3.02 BS01 2CV C 1 F142 S165 K166 F13 S36 K37 A0L5S6 24850863 GVGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVDAM 4pa9 B 3.43 BS01 2CV A 1 S165 K166 Y169 F172 S35 K36 Y39 F42 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4pa9 B 3.43 BS02 2CV B 1 M189 N190 P193 N194 W196 M59 N60 P63 N64 W66 A0L5S6 24850863 VGSVAALLTVVFYIAAVMATNLYGATFPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLTTFTVLNLFIGIIVD 4pe5 A 3.96 BS01 GLY A 1 F484 P516 L517 T518 R523 S688 W731 D732 F758 F439 P471 L472 T473 R478 S608 W651 D652 F678 P35439 KIVNIGAVLSTRKHEQMFREAVNQANKRIQLQATSVTHKPNAIQMALSVCEDLISSQVYAILVSHTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLDMTGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFAQYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTVPQCCYGFCIDLLIKLARTMQFTYEVHLVADGKFGTQERVQNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSCLWLLVGLSVHVVAVMLYLLDRSAMWFSWGVLLNAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQQVSLSILKSHENGFMEDLDKTWVRYQECDSRTCENMAGVFMLVAGGIVAGIFL 4pe5 A 3.96 BS02 QEL B 1 Y109 T110 R115 S132 I133 L135 Y72 T73 R78 S95 I96 L98 P35439 KIVNIGAVLSTRKHEQMFREAVNQANKRIQLQATSVTHKPNAIQMALSVCEDLISSQVYAILVSHTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLDMTGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFAQYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTVPQCCYGFCIDLLIKLARTMQFTYEVHLVADGKFGTQERVQNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSCLWLLVGLSVHVVAVMLYLLDRSAMWFSWGVLLNAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQQVSLSILKSHENGFMEDLDKTWVRYQECDSRTCENMAGVFMLVAGGIVAGIFL 4pe5 B 3.96 BS01 QEL B 1 Q110 I111 F114 F176 P177 E236 Q81 I82 F85 F147 P148 E207 Q00960 KSPPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDCKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNMLNRYLINVTFEGRDLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMTQDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRGYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSLEPFSACVWVMMFVMLLIVIGKAIWLLWGLVFNIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHVFYMLGAAMALSLITFISEHL 4pe5 B 3.96 BS02 GLU B 1 H486 S512 L513 T514 R519 G689 S690 T691 Y731 D732 Y762 H440 S466 L467 T468 R473 G586 S587 T588 Y628 D629 Y659 Q00960 KSPPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDCKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNMLNRYLINVTFEGRDLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMTQDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRGYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSLEPFSACVWVMMFVMLLIVIGKAIWLLWGLVFNIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHVFYMLGAAMALSLITFISEHL 4pe5 D 3.96 BS01 QEL C 1 A107 Q110 I111 F114 F176 P177 E236 A76 Q79 I80 F83 F145 P146 E205 Q00960 PPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDCKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNMLNRYLINVTFEGRDLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMTQDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRFLEPFSACVWVMMFVMLLIGKAIWLLWGLVFIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHEVMSSQLDCDNMAGVFYMLGAAMALSLITFIS 4po0 A 2.73 BS01 NPS A 1 V388 N391 C392 L407 R410 Y411 K414 V449 L453 R485 F488 S489 V387 N390 C391 L406 R409 Y410 K413 V448 L452 R484 F487 S488 G1U9S2 24753230 AHKSEIAHRFNDVGEEHFIGLVLITFSQYLQKCPYEEHAKLVKEVTDLAKACVADESAANCDKSLHDIFGDKICALPSLRDTYGDVADCCEKKEPERNECFLHHKDDKPDLPPFARPEADVLCKAFHDDEKAFFGHYLYEVARRHPYFYAPELLYYAQKYKAILTECCEAADKGACLTPKLDALKEKALISAAQERLRCASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHKECCHGDLLECADDRADLAKYMCEHQETISSHLKECCDKPILEKAHCIYGLHNDETPAGLPAVAEEFVEDKDVCKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLGKAYEATLKKCCATDDPHACYAKVLDEFQPLVDEPKNLVKQNCELYEQLGDYNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGSKCCKHPEAERLPCVEDYLSVVLNRLCVLHEKTPVSEKVTKCCSESLVDRRPCFSALGPDETYVPKEFNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGEFTALLDKCCSAEDKEACFAVEGPKLVESSKATLG 4po0 A 2.73 BS02 NPS A 2 R209 A213 G328 L331 G350 R208 A212 G327 L330 G349 G1U9S2 24753230 AHKSEIAHRFNDVGEEHFIGLVLITFSQYLQKCPYEEHAKLVKEVTDLAKACVADESAANCDKSLHDIFGDKICALPSLRDTYGDVADCCEKKEPERNECFLHHKDDKPDLPPFARPEADVLCKAFHDDEKAFFGHYLYEVARRHPYFYAPELLYYAQKYKAILTECCEAADKGACLTPKLDALKEKALISAAQERLRCASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHKECCHGDLLECADDRADLAKYMCEHQETISSHLKECCDKPILEKAHCIYGLHNDETPAGLPAVAEEFVEDKDVCKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLGKAYEATLKKCCATDDPHACYAKVLDEFQPLVDEPKNLVKQNCELYEQLGDYNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGSKCCKHPEAERLPCVEDYLSVVLNRLCVLHEKTPVSEKVTKCCSESLVDRRPCFSALGPDETYVPKEFNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGEFTALLDKCCSAEDKEACFAVEGPKLVESSKATLG 4po0 A 2.73 BS03 NPS A 3 L394 L398 N405 V409 L529 N541 L544 K545 V548 L393 L397 N404 V408 L528 N540 L543 K544 V547 G1U9S2 24753230 AHKSEIAHRFNDVGEEHFIGLVLITFSQYLQKCPYEEHAKLVKEVTDLAKACVADESAANCDKSLHDIFGDKICALPSLRDTYGDVADCCEKKEPERNECFLHHKDDKPDLPPFARPEADVLCKAFHDDEKAFFGHYLYEVARRHPYFYAPELLYYAQKYKAILTECCEAADKGACLTPKLDALKEKALISAAQERLRCASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHKECCHGDLLECADDRADLAKYMCEHQETISSHLKECCDKPILEKAHCIYGLHNDETPAGLPAVAEEFVEDKDVCKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLGKAYEATLKKCCATDDPHACYAKVLDEFQPLVDEPKNLVKQNCELYEQLGDYNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGSKCCKHPEAERLPCVEDYLSVVLNRLCVLHEKTPVSEKVTKCCSESLVDRRPCFSALGPDETYVPKEFNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGEFTALLDKCCSAEDKEACFAVEGPKLVESSKATLG 4pp9 A 2.58 BS01 2VT A 1 I369 V377 L379 K387 A389 F435 E436 F437 M438 E439 G441 L489 I14 V22 L24 K32 A34 F80 E81 F82 M83 E84 G86 L134 2.7.10.2 Q08881 24767842 SVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESG 4pp9 B 2.58 BS01 2VT B 1 Q367 I369 V377 L379 K387 A389 V419 F435 E436 F437 M438 E439 G441 L489 Q12 I14 V22 L24 K32 A34 V64 F80 E81 F82 M83 E84 G86 L134 2.7.10.2 Q08881 24767842 SVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESG 4ppa A 2.67 BS01 2VU A 1 K387 A389 K391 V419 F435 E436 F437 M438 E439 G441 L489 S499 D500 K32 A34 K36 V57 F73 E74 F75 M76 E77 G79 L127 S137 D138 2.7.10.2 Q08881 24767842 SVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESG 4ppa A 2.67 BS02 2VU B 1 I369 V377 L379 I14 V22 L24 2.7.10.2 Q08881 24767842 SVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESG 4ppb A 2.82 BS01 2VV A 1 A389 K391 V419 F435 E436 F437 M438 E439 H440 G441 L489 S499 A34 K36 V57 F73 E74 F75 M76 E77 H78 G79 L127 S137 2.7.10.2 Q08881 24767842 SVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESG 4ppb B 2.82 BS01 2VV A 1 Q367 I369 V377 Q12 I14 V22 2.7.10.2 Q08881 24767842 SVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESG 4pss A 0.85 BS01 NAP A 1 A6 A7 I14 G15 M16 N18 A19 M20 W22 G43 R44 H45 T46 S49 L62 S63 S64 K76 V78 I94 G95 G96 G97 R98 V99 Y100 Q102 T123 A6 A7 I14 G15 M16 N18 A19 M20 W22 G43 R44 H45 T46 S49 L62 S63 S64 K76 V78 I94 G95 G96 G97 R98 V99 Y100 Q102 T123 U6N356 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 4pzi A 2.15 BS01 NUC B 1 K959 K960 M961 R962 T995 K996 K997 Q998 K4 K5 M6 R7 T40 K41 K42 Q43 2.1.1.43 Q9UMN6 HHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERL 4pzi A 2.15 BS02 NUC C 1 R962 M963 R965 K987 K997 Q998 C999 I1008 R7 M8 R10 K32 K42 Q43 C44 I53 2.1.1.43 Q9UMN6 HHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERL 4pzi A 2.15 BS03 ZN A 1 C966 C969 C972 C1005 C11 C14 C17 C50 2.1.1.43 Q9UMN6 HHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERL 4q30 F 2.03 BS01 NWD F 1 E13 Y61 P89 T91 R96 L138 G141 S142 T143 T174 L192 E193 M196 E10 Y58 P86 T88 R93 L135 G138 S139 T140 T171 L189 E190 M193 P19491 24850223 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGEC 4q8g A 2.10 BS01 ZN A 1 C660 H662 C713 C716 C154 H156 C194 C197 3.1.13.4 P53010 TSDIQTYTSINKYEVPPAYSRLPLTFDFTPFNNTEYSGLDPDVDNHYTNAIIQLYRFIPEMFNFVVGCLKDTTLLTDLGYLFDMMERSHGKICSSSNFQASLKSLTSIKRNMPQKFNRFLLSQLIKEEAQTVNHNITLNQCFGLETEIRTECSCDHYDTTVKLLPSLSISGINQNILPYIEYAMKNVTQKNSICPTCGKTETITQECTVKNLPSVLSLELSLLDTEFSNIRSSKNWLTSEFYGSIIKNKAVLRSTASELKGTSHIFKYELNGYVAKITDNNNETRLVTYVKKYNPKENCFKWLMFNDYLVVEITEEEALKMTYPWKTPEIIIYCDAEELRKPFF 4q8g B 2.10 BS01 ZN B 1 C660 D661 H662 C713 C716 C165 D166 H167 C203 C206 3.1.13.4 P53010 ETSDIQTYTSINKYEVPPAYSRLPLTSGRFGTDNFDFTPFNNTEYSGLDPDVDNHYTNAIIQLYRFIPEMFNFVVGCLKDENFETTLLTDLGYLFDMMERSHGKICSSSNFQASLKSLTKRNMPQKFNRFLLSQLIKEEAQTVNHNITLNQCFGLETEIRTECSCDHYDTTVKLLPSLSISGQNILPYIEYAMKNVTQKNSICPTCGKTETITQECTVKNLPSVLSLELSLLDTEFSNIRSSKNWLTSEFYGSIIKNKAVLRSTASELKGTSHIFKYELNGYVAKITDNNNETRLVTYVKKYNPKENCFKWLMFNDYLVVEITEEEALKMTYPWKTPEIIIYCDAEELRKPFF 4q8h A 3.10 BS01 MG A 1 D910 E912 D1071 D432 E434 D587 3.1.13.4 P53010 PETSDIQTYTSINKYEVPPAYSRLPLTSGRFGTDNFDFTPFNNTEYSGLDPDVDNHYTNAIIQLYRFIPEMFNFVVGCLKDENFETTLLTDLGYLFDMMERSHGKICSSSNFQASLKSLTDKRQEEYLESLCIRESIEDFNSSESIKRNMPQKFNRFLLSQLIKEEAQTVNHNITLNQCFGLETEIRTECSCDHYDTTVKLLPSLSISGINKTGQNILPYIEYAMKNVTQKNSICPTCGKTETITQECTVKNLPSVLSLELSLLDTEFSNIRSSKNWLTSEFYGSIIKNKAVLRSTASELKGTSHIFKYELNGYVAKITDNNNETRLVTYVKKYNPKENCFKWLMFNDYLVVEITEEEALKMTYPWKTPEIIIYCDAEELRKPFFSVDTYSINYDILFRDYFANGIRDTARREYKLLTHDEAPKSGTLVAIDAEFVSLQSELCEIDHIRPKRTALARISIIRGEEGELYGVPFVDDYVVNTNHIEDYLTRYSGILPGDLDPEKSTKRLVRRNVVYRKVWLLMQLGCVFVGHGLNNDFKHININVPRNQIRDTAIYFLQGKRYLSLRYLAYVLLGMNIQEGNHDSIEDAHTALILYKKYLHLKEKAIFEKVLNSVYEEGRAHNFKVPE 4q8h A 3.10 BS02 MG A 2 D910 E912 H1066 D1071 D432 E434 H582 D587 3.1.13.4 P53010 PETSDIQTYTSINKYEVPPAYSRLPLTSGRFGTDNFDFTPFNNTEYSGLDPDVDNHYTNAIIQLYRFIPEMFNFVVGCLKDENFETTLLTDLGYLFDMMERSHGKICSSSNFQASLKSLTDKRQEEYLESLCIRESIEDFNSSESIKRNMPQKFNRFLLSQLIKEEAQTVNHNITLNQCFGLETEIRTECSCDHYDTTVKLLPSLSISGINKTGQNILPYIEYAMKNVTQKNSICPTCGKTETITQECTVKNLPSVLSLELSLLDTEFSNIRSSKNWLTSEFYGSIIKNKAVLRSTASELKGTSHIFKYELNGYVAKITDNNNETRLVTYVKKYNPKENCFKWLMFNDYLVVEITEEEALKMTYPWKTPEIIIYCDAEELRKPFFSVDTYSINYDILFRDYFANGIRDTARREYKLLTHDEAPKSGTLVAIDAEFVSLQSELCEIDHIRPKRTALARISIIRGEEGELYGVPFVDDYVVNTNHIEDYLTRYSGILPGDLDPEKSTKRLVRRNVVYRKVWLLMQLGCVFVGHGLNNDFKHININVPRNQIRDTAIYFLQGKRYLSLRYLAYVLLGMNIQEGNHDSIEDAHTALILYKKYLHLKEKAIFEKVLNSVYEEGRAHNFKVPE 4q96 A 1.85 BS01 III C 1 N18 S19 Q20 V23 Y61 N64 D65 Q68 K71 N16 S17 Q18 V21 Y59 N62 D63 Q66 K69 Q9NQG5 SFSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMED 4q96 A 1.85 BS02 III F 1 C100 P103 C98 P101 Q9NQG5 SFSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMED 4q96 B 1.85 BS01 III C 1 H21 I110 R114 H18 I107 R111 Q9NQG5 FSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMED 4q96 B 1.85 BS02 III F 1 N18 S19 Q20 H21 Q24 S53 N54 L57 Y61 E95 A96 G99 C100 K102 R106 I110 N15 S16 Q17 H18 Q21 S50 N51 L54 Y58 E92 A93 G96 C97 K99 R103 I107 Q9NQG5 FSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMED 4q96 D 1.85 BS01 III C 1 C100 P103 R106 C97 P100 R103 Q9NQG5 FSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMED 4q96 E 1.85 BS01 III C 1 N18 S19 Q20 H21 S53 N54 L57 Y61 A96 C100 K102 R106 I110 N16 S17 Q18 H19 S51 N52 L55 Y59 A94 C98 K100 R104 I108 Q9NQG5 SFSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSME