1vwx g 3.40 BS01 MG g 1 G55 T70 H73 G54 T69 H72 F2Z5B9 VQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVRPKVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQK 1vwx j 3.40 BS01 ZN j 1 C19 C22 C34 C37 C18 C21 C33 C36 TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGITPKPK 1vwx m 3.40 BS01 ZN m 1 C96 C99 C110 C115 C20 C23 C34 C39 P63053 IIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK 1vwx o 3.40 BS01 ZN o 1 C12 C15 C77 C11 C14 C76 P83884 VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQ 1vwz g 3.40 BS01 MG g 1 G55 T70 H73 G54 T69 H72 F2Z5B9 VQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVRPKVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQK 1vwz j 3.40 BS01 ZN j 1 C19 C22 C34 C37 C18 C21 C33 C36 TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGITPKPK 1vwz m 3.40 BS01 ZN m 1 C96 C99 C110 C115 C20 C23 C34 C39 P63053 IIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK 1vwz o 3.40 BS01 ZN o 1 C12 C15 C77 C11 C14 C76 P83884 VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQ 1vx1 g 3.90 BS01 MG g 1 G55 T70 H73 G54 T69 H72 F2Z5B9 VQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVRPKVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQK 1vx1 j 3.90 BS01 ZN j 1 C19 C22 C34 C37 C18 C21 C33 C36 TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGITPKPK 1vx1 m 3.90 BS01 ZN m 1 C96 C99 C110 C115 C20 C23 C34 C39 P63053 IIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK 1vx1 o 3.90 BS01 ZN o 1 C12 C15 C77 C11 C14 C76 P83884 VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQ 1vx2 A 3.90 BS01 NUC 2 1 F32 F103 T104 P105 G106 T109 N110 Q111 I112 Q113 Q132 E136 Y139 R155 Y156 F31 F102 T103 P104 G105 T108 N109 Q110 I111 Q112 Q131 E135 Y138 R154 Y155 Q4GWZ2 SGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEE 1vx2 B 3.90 BS01 NUC 2 1 R28 V114 K115 K116 W117 Q118 V120 H124 R136 F138 R146 N148 Q149 I150 R151 Q157 H158 Q159 Q160 R162 R165 P203 I204 Y205 K216 R8 V94 K95 K96 W97 Q98 V100 H104 R116 F118 R126 N128 Q129 I130 R131 Q137 H138 Q139 Q140 R142 R145 P183 I184 Y185 K196 B6V8C8 VVDPFSKRDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSPADLQNDEVAFRKSKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTVIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQPIYPLHDVFVRKVKMLKKPKFELGKLMELHG 1vx2 C 3.90 BS01 NUC 2 1 Q113 K114 Q115 T116 A118 Q120 R123 K183 T185 C188 G189 S190 L192 R194 V205 Y223 R227 C229 T230 N235 K238 Y250 Q55 K56 Q57 T58 A60 Q62 R65 K125 T127 C130 G131 S132 L134 R136 V147 Y165 R169 C171 T172 N177 K180 Y192 EWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKT 1vx2 D 3.90 BS01 NUC 2 1 V3 Q4 I5 S6 K8 R9 R27 G140 K141 Q145 R146 A147 K151 L156 M157 I158 H159 S160 G161 D162 H174 Q179 G183 K185 P205 D206 V3 Q4 I5 S6 K8 R9 R27 G140 K141 Q145 R146 A147 K151 L156 M157 I158 H159 S160 G161 D162 H174 Q179 G183 K185 P205 D206 Q0Z8U2 MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPTGKIGPKKPLPDHVSIVEPKDEILPTTPISEQK 1vx2 E 3.90 BS01 NUC 2 1 R3 G4 K6 K7 H8 K10 V12 K16 M19 D21 K22 F27 A28 P29 T33 G34 P35 K37 L38 R49 G58 D59 M66 R77 K106 R108 K128 F130 V131 G132 K134 V140 A144 T146 G186 A187 A219 R240 R2 G3 K5 K6 H7 K9 V11 K15 M18 D20 K21 F26 A27 P28 T32 G33 P34 K36 L37 R48 G57 D58 M65 R76 K105 R107 K127 F129 V130 G131 K133 V139 A143 T145 G185 A186 A218 R239 F1RQ91 ARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG 1vx2 F 3.90 BS01 NUC 2 1 A57 N74 M77 M78 H79 G80 R81 N82 N83 G84 L87 M88 R145 N148 W152 R159 F163 R164 I166 A44 N61 M64 M65 H66 G67 R68 N69 N70 G71 L74 M75 R132 N135 W139 R146 F150 R151 I153 F2Z5E6 TPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR 1vx2 G 3.90 BS01 NUC 2 1 K2 N4 P8 Q13 K14 L15 S53 G54 N56 Q59 G60 Q65 G66 V67 L68 R72 L75 C83 Y84 R87 R88 T89 G90 R92 K93 R94 S96 S107 V108 N110 R131 R132 L133 G134 K136 R137 S139 R140 R154 Q155 V157 R159 L162 E165 K167 K168 R170 T171 K172 A173 P174 K175 I176 Q177 R178 R183 L185 Q186 H187 K188 R189 R190 R191 K195 K196 R198 T199 N202 S235 S236 L237 K2 N4 P8 Q13 K14 L15 S53 G54 N56 Q59 G60 Q65 G66 V67 L68 R72 L75 C83 Y84 R87 R88 T89 G90 R92 K93 R94 S96 S107 V108 N110 R131 R132 L133 G134 K136 R137 S139 R140 R154 Q155 V157 R159 L162 E165 K167 K168 R170 T171 K172 A173 P174 K175 I176 Q177 R178 R183 L185 Q186 H187 K188 R189 R190 R191 K195 K196 R198 T199 N202 S235 S236 L237 MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSL 1vx2 H 3.90 BS01 NUC 2 1 P67 R99 K103 R106 K107 S108 R109 T110 K111 Q114 K115 R116 P117 R118 R120 T121 L122 T123 T181 G182 P63 R95 K99 R102 K103 S104 R105 T106 K107 Q110 K111 R112 P113 R114 R116 T117 L118 T119 T177 G178 I3L5B2 SAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQ 1vx2 I 3.90 BS01 NUC 2 1 G2 R5 D6 N7 K10 R11 R12 K13 T14 R18 K19 Y21 K23 K24 R25 K26 Y27 R31 P32 A33 R41 T45 R47 V48 R49 G50 N52 K53 K54 Y55 R56 L58 N64 S66 C71 C72 T73 R74 K75 S86 V97 K98 N99 R141 K144 K148 A176 Q181 C182 R184 D186 G187 G1 R4 D5 N6 K9 R10 R11 K12 T13 R17 K18 Y20 K22 K23 R24 K25 Y26 R30 P31 A32 R40 T44 R46 V47 R48 G49 N51 K52 K53 Y54 R55 L57 N63 S65 C70 C71 T72 R73 K74 S85 V96 K97 N98 R140 K143 K147 A175 Q180 C181 R183 D185 G186 GISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKG 1vx2 J 3.90 BS01 NUC 2 1 P2 V3 R5 S6 W7 V8 C9 R10 K11 T12 T15 R17 R18 F20 R38 N39 K40 R41 R45 F72 E73 K121 S122 H124 H125 R127 R131 Q132 H134 Q140 I144 S146 R150 R162 P164 G171 R172 V173 K174 N177 P1 V2 R4 S5 W6 V7 C8 R9 K10 T11 T14 R16 R17 F19 R37 N38 K39 R40 R44 F71 E72 K120 S121 H123 H124 R126 R130 Q131 H133 Q139 I143 S145 R149 R161 P163 G170 R171 V172 K173 N176 PVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAG 1vx2 K 3.90 BS01 NUC 2 1 M1 L2 M3 K25 L43 K47 Q50 S51 S54 R55 F62 M1 L2 M3 K25 L43 K47 Q50 S51 S54 R55 F62 F1RZ28 MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSR 1vx2 L 3.90 BS01 NUC 2 1 E7 R8 A9 Q11 P14 T15 K30 Y36 N39 I40 G41 L42 K59 S67 I68 R69 R71 K81 M82 Q83 T85 R89 R90 Y92 H94 R97 K98 Y99 R101 K104 R105 H106 K107 N108 M109 E130 R132 P133 L134 S135 K136 T137 R139 G150 F158 E6 R7 A8 Q10 P13 T14 K29 Y35 N38 I39 G40 L41 K58 S66 I67 R68 R70 K80 M81 Q82 T84 R88 R89 Y91 H93 R96 K97 Y98 R100 K103 R104 H105 K106 N107 M108 E129 R131 P132 L133 S134 K135 T136 R138 G149 F157 F2Z4Y8 ADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQKF 1vx2 M 3.90 BS01 NUC 2 1 R33 G34 I35 R36 E37 K40 D57 Y61 K83 G90 L91 C92 K93 D95 R96 R101 K102 V103 V104 G105 C106 S107 C108 R25 G26 I27 R28 E29 K32 D49 Y53 K75 G82 L83 C84 K85 D87 R88 R93 K94 V95 V96 G97 C98 S99 C100 GGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVQASNCDEPMYVKLVEALLAEHQINLIKVDDNKKLGEWVGLCKIDREGNPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK 1vx2 N 3.90 BS01 NUC 2 1 G2 R3 M4 G8 K9 G10 L11 S12 Q13 S14 L16 R20 S48 Q49 G51 V52 R55 A61 Q62 R64 N69 K70 I71 L72 R73 K76 E86 D87 H90 K94 H101 R104 N105 K107 D108 D110 K112 F113 R114 I116 S120 R121 L125 Y128 G1 R2 M3 G7 K8 G9 L10 S11 Q12 S13 L15 R19 S47 Q48 G50 V51 R54 A60 Q61 R63 N68 K69 I70 L71 R72 K75 E85 D86 H89 K93 H100 R103 N104 K106 D107 D109 K111 F112 R113 I115 S119 R120 L124 Y127 GRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA 1vx2 O 3.90 BS01 NUC 2 1 H32 F34 N38 D39 F41 H43 G49 K50 E51 T52 R55 T57 M60 A64 D65 R66 E68 I135 P136 S137 D138 S139 R141 K143 G145 R146 R147 R149 R150 H17 F19 N23 D24 F26 H28 G34 K35 E36 T37 R40 T42 M45 A49 D50 R51 E53 I120 P121 S122 D123 S124 R126 K128 G130 R131 R132 R134 R135 SLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL 1vx2 P 3.90 BS01 NUC 2 1 A39 R40 R42 R47 G48 L56 R59 K77 H79 D82 Y97 G99 A36 R37 R39 R44 G45 L53 R56 K74 H76 D79 Y94 G96 P62844 VEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNG 1vx2 Q 3.90 BS01 NUC 2 1 Q11 V12 F13 K17 T18 T20 H24 K26 K33 N35 G36 E43 R45 R69 R71 K73 G74 G75 G76 H77 V78 A79 Q80 P124 R125 R126 E128 S129 K130 K131 F132 G133 G136 A137 R138 A139 Y141 Q142 K143 S144 Y145 R146 Q6 V7 F8 K12 T13 T15 H19 K21 K28 N30 G31 E38 R40 R64 R66 K68 G69 G70 G71 H72 V73 A74 Q75 P119 R120 R121 E123 S124 K125 K126 F127 G128 G131 A132 R133 A134 Y136 Q137 K138 S139 Y140 R141 Q29201 PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR 1vx2 R 3.90 BS01 NUC 2 1 M1 G2 R3 V4 R5 T6 K7 K11 F28 K32 S43 K44 K45 N48 K49 R60 R67 P122 T123 V124 K129 M1 G2 R3 V4 R5 T6 K7 K11 F28 K32 S43 K44 K45 N48 K49 R60 R67 P122 T123 V124 K129 Q6QAP7 MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFK 1vx2 S 3.90 BS01 NUC 2 1 F28 K34 G35 V36 G37 R38 R39 Y40 W82 F83 L84 N85 R86 Q87 K88 L107 D110 H120 L129 R132 G133 Q134 H135 T136 K137 T138 T139 G140 R141 F23 K29 G30 V31 G32 R33 R34 Y35 W77 F78 L79 N80 R81 Q82 K83 L102 D105 H115 L124 R127 G128 Q129 H130 T131 K132 T133 T134 G135 R136 P62272 PEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRR 1vx2 T 3.90 BS01 NUC 2 1 V4 K7 Q11 Q12 L39 K41 K43 E44 L45 P47 Y48 R62 L66 R67 G71 V72 S74 K77 I78 G81 R82 R84 G86 V87 M88 P89 S90 H91 F92 S96 K97 R101 R102 G119 G120 R121 Q128 R129 D132 R133 V1 K4 Q8 Q9 L36 K38 K40 E41 L42 P44 Y45 R59 L63 R64 G68 V69 S71 K74 I75 G78 R79 R81 G83 V84 M85 P86 S87 H88 F89 S93 K94 R98 R99 G116 G117 R118 Q125 R126 D129 R130 F1RGG1 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKK 1vx2 U 3.90 BS01 NUC 2 1 E33 K51 G52 P53 V54 R55 M56 P57 T58 K59 T60 R62 T65 K67 T68 P69 C70 G71 E72 G73 S74 K75 T76 W77 R79 R83 K86 R87 L88 E18 K36 G37 P38 V39 R40 M41 P42 T43 K44 T45 R47 T50 K52 T53 P54 C55 G56 E57 G58 S59 K60 T61 W62 R64 R68 K71 R72 L73 A1XQU9 AIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIPKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA 1vx2 W 3.90 BS01 NUC 2 1 V2 R3 M4 V6 D9 K12 N16 K19 R20 K22 R28 K32 A58 K71 I75 S76 D80 L83 K88 W89 T105 T106 S107 I110 H120 G122 V1 R2 M3 V5 D8 K11 N15 K18 R19 K21 R27 K31 A57 K70 I74 S75 D79 L82 K87 W88 T104 T105 S106 I109 H119 G121 VRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF 1vx2 X 3.90 BS01 NUC 2 1 G2 K3 C4 R5 L7 R8 T9 R11 R17 H20 W22 H23 D24 K25 K28 A30 T34 H46 K60 Q61 S64 A65 I66 R67 K68 P86 N87 D88 G104 F105 R107 K108 H110 V112 G113 D114 I115 R119 K124 L131 Y134 K137 K138 G1 K2 C3 R4 L6 R7 T8 R10 R16 H19 W21 H22 D23 K24 K27 A29 T33 H45 K59 Q60 S63 A64 I65 R66 K67 P85 N86 D87 G103 F104 R106 K107 H109 V111 G112 D113 I114 R118 K123 L130 Y133 K136 K137 Q6SA96 GKCRGLRTARKLRSHRRDHKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR 1vx2 Y 3.90 BS01 NUC 2 1 R8 T9 R10 K11 F12 T14 A33 T34 P36 K37 M47 Y48 G59 F60 T62 H63 F64 G65 G66 S103 R104 K105 K108 K111 K115 K116 G119 A121 R6 T7 R8 K9 F10 T12 A31 T32 P34 K35 M45 Y46 G57 F58 T60 H61 F62 G63 G64 S101 R102 K103 K106 K109 K113 K114 G117 A119 DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAG 1vx2 Z 3.90 BS01 NUC 2 1 R80 S82 R85 R104 Q106 R40 S42 R45 R64 Q66 RDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKG 1vx2 a 3.90 BS01 NUC 2 1 T2 K4 R5 R6 N7 G9 R10 K13 G14 R15 G16 H17 R28 K32 K34 K37 K38 F39 I41 K70 V75 S76 I79 K82 R87 S88 R89 R92 R95 P97 P98 P99 T1 K3 R4 R5 N6 G8 R9 K12 G13 R14 G15 H16 R27 K31 K33 K36 K37 F38 I40 K69 V74 S75 I78 K81 R86 S87 R88 R91 R94 P96 P97 P98 P49171 TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPP 1vx2 b 3.90 BS01 NUC 2 1 R17 H19 K20 K21 K22 P28 S30 F32 H49 Q51 G69 K70 R72 R16 H18 K19 K20 K21 P27 S29 F31 H48 Q50 G68 K69 R71 PLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH 1vx2 c 3.90 BS01 NUC 2 1 R20 S23 G25 Q26 R16 S19 G21 Q22 Q6QAT1 RVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRL 1vx2 d 3.90 BS01 NUC 2 1 Y7 W8 S9 H10 P11 R12 K13 F14 G15 Q16 G17 R19 R22 C24 N26 R27 I31 R32 K33 Y34 C39 R40 Q41 C42 R44 D56 Y3 W4 S5 H6 P7 R8 K9 F10 G11 Q12 G13 R15 R18 C20 N22 R23 I27 R28 K29 Y30 C35 R36 Q37 C38 R40 D52 Q6QAP6 GFYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD 1vx2 e 3.90 BS01 NUC 2 1 H3 S5 G10 K11 V12 T16 K26 T29 R31 A32 K33 R34 R35 Q37 N39 N44 N56 N58 H1 S3 G8 K9 V10 T14 K24 T27 R29 A30 K31 R32 R33 Q35 N37 N42 N54 N56 HGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS 1vx2 f 3.90 BS01 NUC 2 1 K82 N91 K92 R95 V98 L100 L103 Y105 R116 R118 C121 G129 V130 F131 M132 A133 S134 H135 D137 R138 H139 Y140 C141 G142 K143 C145 L146 T147 Y148 C149 F150 N151 K152 K1 N10 K11 R14 V17 L19 L22 Y24 R35 R37 C40 G48 V49 F50 M51 A52 S53 H54 D56 R57 H58 Y59 C60 G61 K62 C64 L65 T66 Y67 C68 F69 N70 K71 F2Z5U0 KKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMASHFDRHYCGKCCLTYCFNK 1vx2 g 3.90 BS01 NUC 2 1 G61 S63 H64 R100 G60 S62 H63 R99 P63246 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTI 1vx4 g 3.50 BS01 MG g 1 G55 T70 H73 G54 T69 H72 F2Z5B9 VQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVRPKVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQK 1vx4 j 3.50 BS01 ZN j 1 C19 C22 C34 C37 C18 C21 C33 C36 TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGITPKPK 1vx4 m 3.50 BS01 ZN m 1 C96 C99 C110 C115 C20 C23 C34 C39 P63053 IIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK 1vx4 o 3.50 BS01 ZN o 1 C12 C15 C77 C11 C14 C76 P83884 VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQ 1vx5 A 3.50 BS01 NUC 2 1 F32 R102 P105 G106 T109 N110 I112 Q113 Q132 E136 Y139 R155 Y156 F31 R101 P104 G105 T108 N109 I111 Q112 Q131 E135 Y138 R154 Y155 Q4GWZ2 SGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEE 1vx5 B 3.50 BS01 NUC 2 1 R28 V114 K115 K116 W117 Q118 V120 H124 R136 F138 R146 N148 Q149 I150 R151 Q157 H158 Q159 Q160 R162 R165 P203 I204 Y205 K216 R8 V94 K95 K96 W97 Q98 V100 H104 R116 F118 R126 N128 Q129 I130 R131 Q137 H138 Q139 Q140 R142 R145 P183 I184 Y185 K196 B6V8C8 VVDPFSKRDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSPADLQNDEVAFRKSKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTVIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQPIYPLHDVFVRKVKMLKKPKFELGKLMELHG 1vx5 C 3.50 BS01 NUC 2 1 Q113 K114 Q115 T116 R117 A118 G119 Q120 K125 K145 K183 T185 C188 G189 S190 L192 R194 V205 Y223 R227 C229 T230 N235 K238 Y250 Q55 K56 Q57 T58 R59 A60 G61 Q62 K67 K87 K125 T127 C130 G131 S132 L134 R136 V147 Y165 R169 C171 T172 N177 K180 Y192 EWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKT 1vx5 D 3.50 BS01 NUC 2 1 V3 Q4 I5 S6 K8 R9 R27 G140 K141 R143 Q145 R146 A147 K151 L156 M157 I158 H159 S160 G161 H174 R178 Q179 G183 K185 P205 D206 V3 Q4 I5 S6 K8 R9 R27 G140 K141 R143 Q145 R146 A147 K151 L156 M157 I158 H159 S160 G161 H174 R178 Q179 G183 K185 P205 D206 Q0Z8U2 MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPTGKIGPKKPLPDHVSIVEPKDEILPTTPISEQK 1vx5 E 3.50 BS01 NUC 2 1 R3 G4 K6 K7 H8 K10 V12 K16 M19 D21 K22 F27 A28 P29 R30 T33 G34 P35 K37 L38 R49 G58 D59 M66 R77 K106 R108 K128 F130 V131 G132 K134 V140 A144 R145 T146 G186 A187 A219 R240 R2 G3 K5 K6 H7 K9 V11 K15 M18 D20 K21 F26 A27 P28 R29 T32 G33 P34 K36 L37 R48 G57 D58 M65 R76 K105 R107 K127 F129 V130 G131 K133 V139 A143 R144 T145 G185 A186 A218 R239 F1RQ91 ARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG 1vx5 F 3.50 BS01 NUC 2 1 A57 A58 K59 N74 M77 M78 H79 G80 R81 N82 N83 G84 L87 M88 R145 N148 W152 R159 F163 R164 I166 A44 A45 K46 N61 M64 M65 H66 G67 R68 N69 N70 G71 L74 M75 R132 N135 W139 R146 F150 R151 I153 F2Z5E6 TPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR 1vx5 G 3.50 BS01 NUC 2 1 K2 N4 P8 Q13 K14 L15 S53 G54 N56 Q59 G60 Q65 G66 V67 L68 R72 L75 C83 Y84 R87 R88 T89 G90 R92 K93 R94 S96 S107 V108 N110 R131 R132 L133 G134 K136 R137 S139 R140 R154 Q155 V157 R159 L162 E165 K167 K168 R170 T171 K172 A173 P174 K175 I176 Q177 R178 R183 L185 Q186 H187 K188 R189 R190 R191 K195 K196 R198 T199 N202 S235 S236 L237 K2 N4 P8 Q13 K14 L15 S53 G54 N56 Q59 G60 Q65 G66 V67 L68 R72 L75 C83 Y84 R87 R88 T89 G90 R92 K93 R94 S96 S107 V108 N110 R131 R132 L133 G134 K136 R137 S139 R140 R154 Q155 V157 R159 L162 E165 K167 K168 R170 T171 K172 A173 P174 K175 I176 Q177 R178 R183 L185 Q186 H187 K188 R189 R190 R191 K195 K196 R198 T199 N202 S235 S236 L237 MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSL 1vx5 H 3.50 BS01 NUC 2 1 P67 R99 K103 R106 K107 S108 R109 T110 K111 Q114 K115 R116 P117 R118 R120 T121 L122 T123 T181 G182 P63 R95 K99 R102 K103 S104 R105 T106 K107 Q110 K111 R112 P113 R114 R116 T117 L118 T119 T177 G178 I3L5B2 SAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQ 1vx5 I 3.50 BS01 NUC 2 1 G2 R5 D6 N7 K10 R11 R12 K13 T14 K19 Y21 K23 K24 R25 K26 Y27 R31 P32 A33 R41 T45 R47 V48 R49 G50 G51 N52 K53 K54 Y55 R56 L58 N64 S66 C71 C72 T73 R74 K75 S86 V97 K98 N99 R141 K144 K148 A176 Q181 C182 R184 D186 G187 G1 R4 D5 N6 K9 R10 R11 K12 T13 K18 Y20 K22 K23 R24 K25 Y26 R30 P31 A32 R40 T44 R46 V47 R48 G49 G50 N51 K52 K53 Y54 R55 L57 N63 S65 C70 C71 T72 R73 K74 S85 V96 K97 N98 R140 K143 K147 A175 Q180 C181 R183 D185 G186 F2Z5F5 GISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKG 1vx5 J 3.50 BS01 NUC 2 1 P2 V3 S6 W7 V8 C9 R10 K11 T12 T15 R17 R18 F20 R38 N39 K40 R41 R45 F72 E73 K121 S122 H124 H125 R127 R131 Q132 H134 Q140 I144 S146 R150 R162 P164 G171 R172 V173 K174 N177 P1 V2 S5 W6 V7 C8 R9 K10 T11 T14 R16 R17 F19 R37 N38 K39 R40 R44 F71 E72 K120 S121 H123 H124 R126 R130 Q131 H133 Q139 I143 S145 R149 R161 P163 G170 R171 V172 K173 N176 PVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAG 1vx5 K 3.50 BS01 NUC 2 1 M1 L2 M3 K25 L43 K47 Q50 S51 S54 R55 F62 M1 L2 M3 K25 L43 K47 Q50 S51 S54 R55 F62 F1RZ28 MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSR 1vx5 L 3.50 BS01 NUC 2 1 E7 A9 Q11 P14 T15 K30 N39 I40 G41 L42 K59 S67 I68 R69 R71 K81 M82 Q83 T85 R89 R90 Y92 H94 R97 K98 Y99 R101 K104 R105 H106 K107 N108 M109 E130 R132 P133 L134 S135 K136 T137 R139 G150 F158 E6 A8 Q10 P13 T14 K29 N38 I39 G40 L41 K58 S66 I67 R68 R70 K80 M81 Q82 T84 R88 R89 Y91 H93 R96 K97 Y98 R100 K103 R104 H105 K106 N107 M108 E129 R131 P132 L133 S134 K135 T136 R138 G149 F157 F2Z4Y8 ADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQKF 1vx5 M 3.50 BS01 NUC 2 1 R33 G34 I35 R36 E37 K40 D57 Y61 K83 G86 G90 L91 C92 K93 D95 R96 R101 K102 V103 V104 G105 C106 S107 C108 R25 G26 I27 R28 E29 K32 D49 Y53 K75 G78 G82 L83 C84 K85 D87 R88 R93 K94 V95 V96 G97 C98 S99 C100 GGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVQASNCDEPMYVKLVEALLAEHQINLIKVDDNKKLGEWVGLCKIDREGNPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK 1vx5 N 3.50 BS01 NUC 2 1 G2 R3 M4 H5 G8 K9 G10 L11 S12 Q13 S14 L16 R20 S48 Q49 G51 V52 R55 A61 Q62 R64 N69 K70 I71 L72 R73 K76 E86 D87 H90 K94 H101 R104 N105 K107 D108 D110 K112 F113 R114 I116 L117 S120 R121 Y128 G1 R2 M3 H4 G7 K8 G9 L10 S11 Q12 S13 L15 R19 S47 Q48 G50 V51 R54 A60 Q61 R63 N68 K69 I70 L71 R72 K75 E85 D86 H89 K93 H100 R103 N104 K106 D107 D109 K111 F112 R113 I115 L116 S119 R120 Y127 GRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA 1vx5 O 3.50 BS01 NUC 2 1 H32 F34 N38 D39 F41 H43 G49 K50 E51 T52 R55 T57 M60 A64 D65 R66 E68 I135 P136 S137 D138 S139 R141 K143 G145 R146 R147 R149 R150 H17 F19 N23 D24 F26 H28 G34 K35 E36 T37 R40 T42 M45 A49 D50 R51 E53 I120 P121 S122 D123 S124 R126 K128 G130 R131 R132 R134 R135 SLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL 1vx5 P 3.50 BS01 NUC 2 1 A39 R40 R42 R47 G48 L56 R59 K77 H79 D82 Y97 G99 A36 R37 R39 R44 G45 L53 R56 K74 H76 D79 Y94 G96 P62844 VEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNG 1vx5 Q 3.50 BS01 NUC 2 1 Q11 V12 F13 K17 T18 T20 H24 K26 K33 N35 G36 E43 R45 R69 R71 K73 G74 G75 G76 H77 V78 A79 P124 R125 R126 E128 S129 K130 K131 F132 G133 G136 A137 R138 A139 Y141 Q142 K143 S144 Y145 R146 Q6 V7 F8 K12 T13 T15 H19 K21 K28 N30 G31 E38 R40 R64 R66 K68 G69 G70 G71 H72 V73 A74 P119 R120 R121 E123 S124 K125 K126 F127 G128 G131 A132 R133 A134 Y136 Q137 K138 S139 Y140 R141 Q29201 PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR 1vx5 R 3.50 BS01 NUC 2 1 M1 G2 R3 V4 R5 T6 K7 K10 K11 F28 K32 S43 K44 K45 N48 K49 R60 R67 P122 T123 K129 M1 G2 R3 V4 R5 T6 K7 K10 K11 F28 K32 S43 K44 K45 N48 K49 R60 R67 P122 T123 K129 Q6QAP7 MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFK 1vx5 S 3.50 BS01 NUC 2 1 F28 K34 G35 V36 G37 R38 Y40 W82 F83 L84 N85 R86 Q87 K88 L107 H120 L129 R132 G133 H135 T136 K137 T138 T139 G140 R141 F23 K29 G30 V31 G32 R33 Y35 W77 F78 L79 N80 R81 Q82 K83 L102 H115 L124 R127 G128 H130 T131 K132 T133 T134 G135 R136 P62272 PEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRR 1vx5 T 3.50 BS01 NUC 2 1 V4 T5 K7 Q11 Q12 K41 E44 L45 P47 Y48 S59 R62 Y65 L66 R67 S74 K77 I78 G81 R82 R84 G86 V87 M88 P89 S90 H91 F92 S96 K97 R101 R102 G119 G120 R121 Q128 R129 D132 V1 T2 K4 Q8 Q9 K38 E41 L42 P44 Y45 S56 R59 Y62 L63 R64 S71 K74 I75 G78 R79 R81 G83 V84 M85 P86 S87 H88 F89 S93 K94 R98 R99 G116 G117 R118 Q125 R126 D129 F1RGG1 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKK 1vx5 U 3.50 BS01 NUC 2 1 E33 K51 G52 P53 V54 R55 M56 P57 T58 K59 T60 T65 K67 T68 P69 C70 G71 E72 G73 S74 K75 T76 W77 R79 R83 K86 R87 L88 E18 K36 G37 P38 V39 R40 M41 P42 T43 K44 T45 T50 K52 T53 P54 C55 G56 E57 G58 S59 K60 T61 W62 R64 R68 K71 R72 L73 A1XQU9 AIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIPKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA 1vx5 W 3.50 BS01 NUC 2 1 V2 R3 M4 V6 D9 K12 N16 K19 R20 R28 K32 R57 A58 K71 I75 S76 D80 L83 K88 W89 T105 T106 S107 I110 H120 G122 V1 R2 M3 V5 D8 K11 N15 K18 R19 R27 K31 R56 A57 K70 I74 S75 D79 L82 K87 W88 T104 T105 S106 I109 H119 G121 VRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF 1vx5 X 3.50 BS01 NUC 2 1 G2 K3 C4 R5 L7 R8 R11 R17 H20 W22 H23 K25 K28 T34 K37 S45 H46 K60 N63 S64 A65 I66 R67 K68 N87 D88 G89 G104 F105 R107 K108 H110 V112 G113 I115 R119 K124 S129 L131 K137 K138 G1 K2 C3 R4 L6 R7 R10 R16 H19 W21 H22 K24 K27 T33 K36 S44 H45 K59 N62 S63 A64 I65 R66 K67 N86 D87 G88 G103 F104 R106 K107 H109 V111 G112 I114 R118 K123 S128 L130 K136 K137 Q6SA96 GKCRGLRTARKLRSHRRDHKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR 1vx5 Y 3.50 BS01 NUC 2 1 R8 T9 K11 F12 T14 A33 T34 P36 K37 M47 Y48 G59 F60 T62 H63 F64 G65 G66 R93 S103 R104 K105 K108 K111 K115 K116 G119 A121 R6 T7 K9 F10 T12 A31 T32 P34 K35 M45 Y46 G57 F58 T60 H61 F62 G63 G64 R91 S101 R102 K103 K106 K109 K113 K114 G117 A119 DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTSRKQRKERKNRMKKVRGTAKANVGAG 1vx5 Z 3.50 BS01 NUC 2 1 R80 G81 S82 R85 R104 Q106 R40 G41 S42 R45 R64 Q66 RDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKG 1vx5 a 3.50 BS01 NUC 2 1 T2 K4 R5 R6 N7 G9 R10 K13 G14 R15 G16 H17 R28 K32 K34 K37 K38 F39 I41 K70 V75 S76 I79 R85 N86 R87 S88 R89 R92 R95 P97 P98 P99 T1 K3 R4 R5 N6 G8 R9 K12 G13 R14 G15 H16 R27 K31 K33 K36 K37 F38 I40 K69 V74 S75 I78 R84 N85 R86 S87 R88 R91 R94 P96 P97 P98 P49171 TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPP 1vx5 b 3.50 BS01 NUC 2 1 R17 H19 K21 K22 P28 S30 F32 H49 Q51 G68 G69 K70 R72 R16 H18 K20 K21 P27 S29 F31 H48 Q50 G67 G68 K69 R71 PLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH 1vx5 c 3.50 BS01 NUC 2 1 R20 S23 G25 Q26 R16 S19 G21 Q22 Q6QAT1 RVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRL 1vx5 d 3.50 BS01 NUC 2 1 Y7 W8 S9 H10 P11 R12 K13 F14 G15 Q16 G17 R19 R22 C24 N26 R27 H28 I31 R32 K33 Y34 C39 R40 Q41 C42 R44 D56 Y3 W4 S5 H6 P7 R8 K9 F10 G11 Q12 G13 R15 R18 C20 N22 R23 H24 I27 R28 K29 Y30 C35 R36 Q37 C38 R40 D52 Q6QAP6 GFYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD 1vx5 e 3.50 BS01 NUC 2 1 R8 K11 V12 R13 Q15 T16 P17 V19 K21 K26 T29 R31 K33 R34 R35 Q37 N39 N44 N56 N58 R6 K9 V10 R11 Q13 T14 P15 V17 K19 K24 T27 R29 K31 R32 R33 Q35 N37 N42 N54 N56 HGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS 1vx5 f 3.50 BS01 NUC 2 1 K82 N91 K92 R95 V98 L100 L103 Y105 R116 R118 C121 G129 V130 M132 A133 S134 H135 D137 R138 H139 Y140 C141 G142 K143 C145 L146 T147 Y148 C149 F150 N151 K152 K1 N10 K11 R14 V17 L19 L22 Y24 R35 R37 C40 G48 V49 M51 A52 S53 H54 D56 R57 H58 Y59 C60 G61 K62 C64 L65 T66 Y67 C68 F69 N70 K71 F2Z5U0 KKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMASHFDRHYCGKCCLTYCFNK 1vx5 g 3.50 BS01 NUC 2 1 G61 S63 H64 R100 G60 S62 H63 R99 P63246 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTI 3j6v B 7.00 BS01 NUC A 1 R138 R158 Y159 F160 K161 G162 G163 T166 N167 P169 L170 R89 R109 Y110 F111 K112 G113 G114 T117 N118 P120 L121 P82923 24799711 RILSEPLKHSDFFNVKELFSVRSLFNARVHLGHKAGCRHRFMEPYIFGSRLGQDIIDLEQTATHLQLALNFTAHVAFRGGIILFVSRARQFSHLIESTARSCGEYAHTRYFKGGLLTNAPLLLGARVRLPDLIIFLHTLNNVFEPHVAVRDAAKMSIPTVGVVDTNCNPCLITYPVPGNDDSPPAVQLFCQLFQTAVTRAKEKRRQLEALYRLQGAPGPHPANPAAPGAPSPGAQAQLGMGHSP 3j6v E 7.00 BS01 NUC A 1 R226 N230 M231 T232 A233 K234 E235 K238 K260 A261 T262 E263 D266 R269 K270 T297 K299 R300 T301 H302 K304 H317 A334 K335 V336 S337 G338 S339 V340 N341 W408 R419 V421 L425 R138 N142 M143 T144 A145 K146 E147 K150 K172 A173 T174 E175 D178 R181 K182 T209 K211 R212 T213 H214 K216 H229 A246 K247 V248 S249 G250 S251 V252 N253 W320 R331 V333 L337 Q2KID9 24799711 FFTKLTADELWKGALAETGAGARKGRGKRTKRKRRKDLNRGQIIGEGRRGFLWPGLNAPLMKSGAIQTITQRSKEEQEKVEADMVQQREEWDRKRKMKVKRERGWSGNSWGGISLGPPDPGPNGETYDDFDTRILEVRNVFNMTAKEGRKRSVRVLVAVGNGRGAAGFAIGKATERADAFRKAKNRAVHYLHYIERYEDHTIYHDISLTFKRTHIKMKKQPRGYGLRCHRAITTICRLIGIKDMYAKVSGSVNMLSLTRGLFQGLSRQETHQQLADKKSLHVVEFREECGPLPIVVASPQGALRKDPEPEDEVPDIKLDWDDVKAVQGMKRSVWSGLKRAAT 3j6v F 7.00 BS01 NUC A 1 M1 Y4 K50 M51 A53 H54 S55 T72 I89 R90 P91 V93 K95 M1 Y4 K50 M51 A53 H54 S55 T72 I89 R90 P91 V93 K95 P82931 24799711 MPRYELALILKAMQRPETAAALKRTLEALMDRGAVVRSLENLGERTLPYKMSAHSQRHTRGGYFLVDFYAPTTTVASIMEHLSRDIDVIRPNVVKHPLTQEVKECEGIVPVPLEEKLYSTKKRK 3j6v G 7.00 BS01 NUC A 1 P39 E40 Y41 Q42 D43 P160 I161 L162 G164 G165 F167 R192 K194 K195 P196 R197 M199 Q207 E211 R216 P218 K221 P1 E2 Y3 Q4 D5 P122 I123 L124 G126 G127 F129 R154 K156 K157 P158 R159 M161 Q169 E173 R178 P180 K183 Q3T040 24799711 PEYQDPQIDKEYYRKPLAQLTEEETYERELRKTQVIKAAPATKTSSVFEDPVISKFTNMMMKGGNKILARSLMTQTLEAVKRKQFEKYHAASAEEQATVERNPYTIFHQALKNCEPVIGLVPILKGGHFYQVPVPLAERRRRFLAMKWMITECREKKPRRMLMPEKLSQELLEAFCNRGPVIKRKHDMHKMAEANRALAHYRWW 3j6v I 7.00 BS01 NUC A 1 L179 R180 K182 L184 S186 E187 S189 S191 K192 D193 L194 I195 G196 R198 W199 L200 I201 K202 E204 L205 E206 E207 M208 L209 V210 E211 K212 L213 S214 D215 Y218 T307 Q308 D309 G336 R337 S338 S339 V376 R377 E378 R379 K380 P382 E385 G386 A387 R388 R389 K390 W393 K394 K395 R396 L112 R113 K115 L117 S119 E120 S122 S124 K125 D126 L127 I128 G129 R131 W132 L133 I134 K135 E137 L138 E139 E140 M141 L142 V143 E144 K145 L146 S147 D148 Y151 T240 Q241 D242 G269 R270 S271 S272 V309 R310 E311 R312 K313 P315 E318 G319 A320 R321 R322 K323 W326 K327 K328 R329 Q58DQ5 24799711 SYTVDFIKKQIEEFNIGKRHLANMMGEDPETFTQEDVDRAITYLFPSGLFEKRARPIMKHPEEIFPKQRAVQWGEDGRPFHFLFYTGKQSYYSLMHEAYGKVLHAEERQDQLRAKGLFSEKSKSKDLIGSRWLIKEELEEMLVEKLSDQDYAQFIRLLERLSALPCDAAEEEFVGRFRRTVTVQSKKHLIEPLQYDEQGMAFSTGQGKRKTANAEAVVYGHGSGKIEINGVDYLLYFPVTQDREQLMFPFHFLDRLGKHDVTCTVSGGGRSSQAGAIRLAMSRALCSFITEDEVEWMRQAGLLTTDPRVRERKKPGQEGARRKFTWKKR 3j6v J 7.00 BS01 NUC A 1 R113 R117 K122 S123 V124 H125 I126 F127 K128 H130 V132 E135 R137 R113 R117 K122 S123 V124 H125 I126 F127 K128 H130 V132 E135 R137 P82670 24799711 MAVRAVFGALGRRLWQGSKNFSVSSSRSNIAKNDGFLLSTSMKWVQFSNLHVDVPKDLTKPTITISDEPDTLYKRLSVLVKGHDKAVLDSYEYFAVLAAKELGISVKVHEPPRKIERFTLLKSVHIFKKHRVQYEMRTLYRCLELEHLTGSTADVYLEYIQRNLPEGVAMEVTKTRLEQLPEHIKKPVWETTPEEKGDSKS 3j6v K 7.00 BS01 NUC A 1 A55 I69 P70 Q72 S74 S75 L76 R77 S94 Y95 N96 N97 H107 G116 T117 R121 N122 A123 K125 I184 H186 N187 G188 C189 R190 P191 R192 K193 A194 R195 R196 L197 A31 I45 P46 Q48 S50 S51 L52 R53 S70 Y71 N72 N73 H83 G92 T93 R97 N98 A99 K101 I160 H162 N163 G164 C165 R166 P167 R168 K169 A170 R171 R172 L173 P82911 24799711 AGVPAPTIHMSAQQMQDAAAKEEVEKAETPAPAPSRSSFSIYPPIPGQESSLRWAGKKFEEIPIAHIKASYNNTQIHVVSAAHQPLARASCGTEGFRNAKKGTGIAAQTAGIAAAAKATGKGVTHVRVVVKGLGPGRLSAIKGLTMGGLEVISITDNTPIPHNGCRPRKARRL 3j6v L 7.00 BS01 NUC A 1 A31 L36 R39 P41 P42 F44 P45 P46 S47 K48 P51 T52 G54 R55 P56 Q57 K59 K69 K72 N74 S75 N77 R78 S86 F94 P96 G97 E98 G99 G112 G113 R114 T115 Q116 D117 L118 P119 G120 V121 K122 V126 R127 G128 K129 K137 K138 K139 A1 L6 R9 P11 P12 F14 P15 P16 S17 K18 P21 T22 G24 R25 P26 Q27 K29 K39 K42 N44 S45 N47 R48 S56 F64 P66 G67 E68 G69 G82 G83 R84 T85 Q86 D87 L88 P89 G90 V91 K92 V96 R97 G98 K99 K107 K108 K109 Q29RU1 24799711 ATLNQLHRRGPPKFPPSKPGPTEGRPQLKGVVLRTFIRKPKKPNSANRKCCRVRLSTGREAVCFIPGEGHNLQEHHVVLVQGGRTQDLPGVKLKVVRGKYDCGHVQKKK 3j6v N 7.00 BS01 NUC A 1 V16 V17 P18 S19 G23 Q24 A25 S27 Y28 Y29 D31 W32 R33 M34 L35 R36 K39 R40 M43 E74 I75 A77 L78 P79 R80 C83 R86 R88 R96 P97 R98 G99 V100 R105 L106 S107 R108 I109 I127 V16 V17 P18 S19 G23 Q24 A25 S27 Y28 Y29 D31 W32 R33 M34 L35 R36 K39 R40 M43 E74 I75 A77 L78 P79 R80 C83 R86 R88 R96 P97 R98 G99 V100 R105 L106 S107 R108 I109 I127 Q6B860 24799711 MATSMLGSLLRIVRQVVPSSASGQARSYYVDWRMLRDVKRRKMAYEYADERLRINSLRKNTILPKHLQEVADEEIAALPRDSCPVRIRNRCVMTSRPRGVKRRWRLSRIVFRHLADHGQLSGIQRAIW 3j6v O 7.00 BS01 NUC A 1 K106 K107 L110 Q127 A130 L131 K134 Y138 H145 K147 K149 A150 R153 Y154 M157 D160 K161 M165 P193 Y194 K197 I198 H199 R200 R201 L202 K53 K54 L57 Q74 A77 L78 K81 Y85 H92 K94 K96 A97 R100 Y101 M104 D107 K108 M112 P140 Y141 K144 I145 H146 R147 R148 L149 E1BBB4 24799711 TQKPVQQSQEDDPPPSMLLKDYQNVPGIEKVDDVVKRLISLEMANKKEMLKIKKEQLMSKVVENPKDTSSLEAQIVALTVKIRSYEEHMQKHQKDKAHKRYLLMSIDKRQKMLKNLRKTNYPVFEKTCKELGIEYTFPPPYHRKIHRRLATKKALCIRVFQEVQKLKKQKRALKTAAAAAQKQGQRNPESPSEARSEAIKETQ 3j6v P 7.00 BS01 NUC A 1 H16 R20 L21 L23 C26 T27 N39 K40 C41 P42 R43 D44 I77 G78 C79 G80 A81 L119 L120 Q123 T127 E128 A129 T132 H1 R5 L6 L8 C11 T12 N24 K25 C26 P27 R28 D29 I62 G63 C64 G65 A66 L104 L105 Q108 T112 E113 A114 T117 P82915 24799711 HLTIRLALGGCTNRPFYRIVAAHNKCPRDGRFVEQLGSYDPMPNSHGEKLVALNLDRIRHWIGCGAHLSKPVEKLLGLSGFFPLHPMVITNAERLRRKRAQEVLLAAQKTDTEATETKEN 3j6v Q 7.00 BS01 NUC A 1 M1 S2 V3 R5 S6 V8 K11 W12 I13 V30 R32 L33 V34 L35 P37 Y38 L39 L40 K41 Y42 K47 T48 Y49 R73 T74 K75 H76 V77 H79 S127 T128 T129 Q130 M1 S2 V3 R5 S6 V8 K11 W12 I13 V30 R32 L33 V34 L35 P37 Y38 L39 L40 K41 Y42 K47 T48 Y49 R73 T74 K75 H76 V77 H79 S127 T128 T129 Q130 P82916 24799711 MSVVRSSVHAKWIVGKVIGTAMQKTAKVRVTRLVLDPYLLKYFNKRKTYFAHDALQQCTVGDIVLLKALPVPRTKHVKHELAEIVFKVGQVVDPVTGKRCAGTTYLESPVDLETTPLAKNLEELSLSTTQ 3j6v R 7.00 BS01 NUC A 1 V39 E40 I41 Q42 E43 G44 K45 T46 I48 I49 E50 G51 R52 I53 T54 G55 T56 P57 K58 E59 S60 P61 N62 P63 P64 N65 P66 S67 Q69 C70 P71 I72 C73 R74 W75 H79 K80 R94 H96 G98 M99 L100 P101 R102 Q109 H112 R113 E116 E117 K120 H123 R124 V1 E2 I3 Q4 E5 G6 K7 T8 I10 I11 E12 G13 R14 I15 T16 G17 T18 P19 K20 E21 S22 P23 N24 P25 P26 N27 P28 S29 Q31 C32 P33 I34 C35 R36 W37 H41 K42 R56 H58 G60 M61 L62 P63 R64 Q71 H74 R75 E78 E79 K82 H85 R86 P82919 24799711 VEIQEGKTTIIEGRITGTPKESPNPPNPSGQCPICRWNLKHKYSYEDVLLLSQFIRPHGGMLPRSITGLCQEEHRKIEECVKMAHRAGLLPNHRPKLPEGFFPKTRPRLNRYLTRWSPRSVKPIYNKGHRWNKVRMAVGSPLLKDNVSYTGRPLVLYH 3j6v U 7.00 BS01 NUC A 1 L35 R43 Y44 E46 K47 R50 R52 Q53 R54 S56 Y57 C60 L35 R43 Y44 E46 K47 R50 R52 Q53 R54 S56 Y57 C60 P82920 24799711 MAKHLKFIARTVMVQEGNVEGAYRTLNRILTMDGLIEDIKRRRYYEKPCRRRQRESYETCRRIYNMEMARKINFLMRKNRADPWQGC 3j6v V 7.00 BS01 NUC A 1 G45 K46 N48 A56 H57 P59 H60 I62 A63 H64 G67 W68 K94 G2 K3 N5 A13 H14 P16 H17 I19 A20 H21 G24 W25 K51 Q2M2T7 24799711 VGKGNKPVTYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAERTVEDVFLRKFMLGTFPGCLADQLILKRRANQVEICALVLRQLPAHKFYFLVGYSETLLSHFYKCPVRLHLQTVPSKVVYKYI 3wc9 A 2.82 BS01 FPS A 1 S53 F54 Y73 R77 V179 G180 L183 M207 G208 L211 Q212 Y276 C289 S18 F19 Y38 R42 V144 G145 L148 M172 G173 L176 Q177 Y241 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRT 3wc9 B 2.82 BS01 FPS B 1 S53 F54 R77 V179 G180 L183 M207 L211 Q212 N215 R218 Y276 C289 S18 F19 R42 V144 G145 L148 M172 L176 Q177 N180 R183 Y241 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wc9 C 2.82 BS01 FPS C 1 R52 S53 F54 Y73 R77 V179 G180 L183 M207 L211 Q212 Y276 C289 R17 S18 F19 Y38 R42 V144 G145 L148 M172 L176 Q177 Y241 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wc9 D 2.82 BS01 FPS D 1 R52 S53 F54 R77 V179 G180 L183 M207 L211 Q212 Y276 F288 C289 R17 S18 F19 R42 V144 G145 L148 M172 L176 Q177 Y241 F253 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wc9 D 2.82 BS02 FPS D 2 F54 Y73 R77 D80 V179 L183 E222 F288 F19 Y38 R42 D45 V144 L148 E187 F253 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wc9 E 2.82 BS01 FPS E 1 R52 S53 F54 Y73 R77 V179 G180 L183 M207 L211 Q212 N215 R218 Y276 F288 C289 R17 S18 F19 Y38 R42 V144 G145 L148 M172 L176 Q177 N180 R183 Y241 F253 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wc9 F 2.82 BS01 FPS F 1 S53 F54 Y73 R77 V179 G180 L183 M207 L211 Q212 N215 R218 Y276 C289 S18 F19 Y38 R42 V144 G145 L148 M172 L176 Q177 N180 R183 Y241 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wca A 2.24 BS01 FPS A 1 S42 S44 F45 Y64 V171 G172 L175 A196 M199 G200 L203 Q204 N207 Y270 S15 S17 F18 Y37 V144 G145 L148 A169 M172 G173 L176 Q177 N180 Y243 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wca A 2.24 BS02 MG A 1 D71 E74 D75 Y163 D44 E47 D48 Y136 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wca B 2.24 BS01 FPS B 1 S42 S44 F45 Y64 R68 V171 G172 L175 Y179 M199 G200 L203 Q204 N207 Y270 S15 S17 F18 Y37 R41 V144 G145 L148 Y152 M172 G173 L176 Q177 N180 Y243 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wca B 2.24 BS02 MG B 1 D71 E74 D44 E47 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wca B 2.24 BS03 MG B 2 D71 D75 D44 D48 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wca C 2.24 BS01 FPS C 1 S42 S44 F45 Y64 R68 V171 G172 L175 A196 M199 G200 L203 Q204 N207 Y270 S15 S17 F18 Y37 R41 V144 G145 L148 A169 M172 G173 L176 Q177 N180 Y243 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wca C 2.24 BS02 FPS C 2 F45 F63 Y64 L67 R68 D71 V167 V171 Q204 D211 D215 F18 F36 Y37 L40 R41 D44 V140 V144 Q177 D184 D188 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wca D 2.24 BS01 FPS D 1 S42 S44 F45 Y64 V171 G172 L175 Y179 M199 G200 L203 Q204 N207 S15 S17 F18 Y37 V144 G145 L148 Y152 M172 G173 L176 Q177 N180 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcb A 3.00 BS01 8PH A 1 S42 S44 F45 Y64 R68 G172 L175 M199 G200 L203 S15 S17 F18 Y37 R41 G145 L148 M172 G173 L176 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFTFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcb B 3.00 BS01 8PH B 1 S42 R43 S44 F45 Y64 R68 N207 S15 R16 S17 F18 Y37 R41 N180 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFTFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcb D 3.00 BS01 8PH D 1 S42 S44 Y64 R68 S15 S17 Y37 R41 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFTFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcc A 2.32 BS01 E5S A 1 F45 Y64 L67 D71 V167 A168 V171 L175 M199 G200 L203 Q204 Y270 S283 Q287 F18 Y37 L40 D44 V140 A141 V144 L148 M172 G173 L176 Q177 Y243 S256 Q260 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcc B 2.32 BS01 E5S B 1 F45 V60 F63 Y64 L67 D71 V167 V171 L175 M199 L203 Y270 S283 P286 Q287 F18 V33 F36 Y37 L40 D44 V140 V144 L148 M172 L176 Y243 S256 P259 Q260 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcc C 2.32 BS01 E5S C 1 F45 I49 V60 Y64 L67 D71 V167 A168 V171 L175 Y179 L203 Q204 Y270 F282 S283 Q287 F19 I23 V34 Y38 L41 D45 V141 A142 V145 L149 Y153 L177 Q178 Y244 F256 S257 Q261 2.5.1.21 Q4CWB4 24789335 NDEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcc D 2.32 BS01 E5S D 1 F45 V60 Y64 L67 D71 V167 V171 L175 Y179 M199 L203 Q204 Y270 F282 S283 P286 Q287 F18 V33 Y37 L40 D44 V140 V144 L148 Y152 M172 L176 Q177 Y243 F255 S256 P259 Q260 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcd A 2.75 BS01 RWY A 1 V175 A176 V179 G180 L183 M207 G208 L211 C289 P292 V140 A141 V144 G145 L148 M172 G173 L176 C254 P257 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcd B 2.75 BS01 RWY B 1 F54 A176 V179 G180 L183 M207 G208 L211 F288 C289 P292 Q293 F19 A141 V144 G145 L148 M172 G173 L176 F253 C254 P257 Q258 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcd D 2.75 BS01 RWY D 1 A176 V179 G180 M207 G208 L211 F288 C289 P292 A141 V144 G145 M172 G173 L176 F253 C254 P257 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcd E 2.75 BS01 RWY E 1 Y73 R77 A176 V179 G180 L183 M207 G208 L211 F288 C289 P292 Q293 Y38 R42 A141 V144 G145 L148 M172 G173 L176 F253 C254 P257 Q258 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wce A 2.75 BS01 ER4 A 1 F45 Y64 L67 R68 D71 V167 A168 V171 G172 L175 Y179 M199 G200 L203 Y270 F18 Y37 L40 R41 D44 V140 A141 V144 G145 L148 Y152 M172 G173 L176 Y243 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wce B 2.75 BS01 ER4 B 1 F45 F63 Y64 L67 R68 D71 A168 V171 L175 M199 G200 L203 Y270 S283 F18 F36 Y37 L40 R41 D44 A141 V144 L148 M172 G173 L176 Y243 S256 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wce C 2.75 BS01 ER4 C 1 F45 Y64 L67 R68 D71 V167 A168 V171 L175 Y179 M199 G200 L203 Y270 S283 F18 Y37 L40 R41 D44 V140 A141 V144 L148 Y152 M172 G173 L176 Y243 S256 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wce D 2.75 BS01 ER4 D 1 F45 F63 Y64 L67 R68 D71 A168 V171 L175 Y179 M199 G200 L203 Y270 S283 F18 F36 Y37 L40 R41 D44 A141 V144 L148 Y152 M172 G173 L176 Y243 S256 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcf A 2.22 BS01 BH8 A 1 L76 R77 D80 V179 G180 L183 M207 L211 Q212 N215 C289 L41 R42 D45 V144 G145 L148 M172 L176 Q177 N180 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcf B 2.22 BS01 BH8 B 1 S51 R52 S53 F54 Y73 V179 G180 L183 M207 L211 Q212 N215 C289 S16 R17 S18 F19 Y38 V144 G145 L148 M172 L176 Q177 N180 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcf C 2.22 BS01 BH8 C 1 R52 S53 A176 L183 F187 M207 L211 N215 R218 Y276 C289 R17 S18 A141 L148 F152 M172 L176 N180 R183 Y241 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcf D 2.22 BS01 BH8 D 1 T50 S51 R52 S53 F54 Y73 A176 G180 L211 T15 S16 R17 S18 F19 Y38 A141 G145 L176 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcf E 2.22 BS01 BH8 E 1 S51 R52 S53 F54 A176 V179 G180 L183 M207 L211 N215 R218 C289 S16 R17 S18 F19 A141 V144 G145 L148 M172 L176 N180 R183 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcf F 2.22 BS01 BH8 F 1 S51 R52 S53 F54 Y73 V179 G180 L183 G208 L211 Q212 N215 S16 R17 S18 F19 Y38 V144 G145 L148 G173 L176 Q177 N180 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcg A 2.80 BS01 BH3 A 1 S42 R43 S44 Y64 R68 D71 V167 V171 G172 L175 M199 L203 Q204 S15 R16 S17 Y37 R41 D44 V140 V144 G145 L148 M172 L176 Q177 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcg B 2.80 BS01 BH3 B 1 S42 S44 F45 Y64 R68 D71 V167 V171 G172 L175 M199 L203 Q204 S15 S17 F18 Y37 R41 D44 V140 V144 G145 L148 M172 L176 Q177 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcg C 2.80 BS01 BH3 C 1 S42 S44 F45 Y64 R68 D71 V167 V171 G172 L175 M199 G200 L203 Q204 S15 S17 F18 Y37 R41 D44 V140 V144 G145 L148 M172 G173 L176 Q177 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wcg D 2.80 BS01 BH3 D 1 S42 R43 S44 F45 Y64 R68 D71 V167 V171 G172 L175 M199 L203 S15 R16 S17 F18 Y37 R41 D44 V140 V144 G145 L148 M172 L176 2.5.1.21 Q4CWB4 24789335 DEDLRFCYDILQAVSRSFAVVIMELDEEMRDAVCIFYLVLRALDTVEDDMSIPVEFKLRELPKFHEHLHDTTWCMSGVGVGRERELLERYTHVTRAYSRLGKAYQDVISGICERMANGMCDFLTRKVETKADYDLYCHYVAGLVGHGLTLLYVSSGLEDVRLADDLTNANHMGLFLQKTNIIRDFYEDICEVPPRVFWPREIWEKYTDDLHAFKDELHEAKAVECLNAMVADALVHVPHVVEYLASLRDPSVFAFSAIPQVMAMATLSLVFNNKDVFHTKVKTTRGATARIFHYSTELQATLQMLKTYTLRLAARMNAQDACYDRIEHLVNDAIRAMESHQ 3wch A 2.50 BS01 8PH A 1 R77 D80 D84 V175 A176 V179 G180 L183 M207 G208 L211 Q212 C289 R42 D45 D49 V140 A141 V144 G145 L148 M172 G173 L176 Q177 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wch A 2.50 BS02 8PH A 2 F54 V69 F72 Y73 L183 F288 P292 F19 V34 F37 Y38 L148 F253 P257 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wch A 2.50 BS03 8PH A 3 T50 S51 R52 S53 N215 T15 S16 R17 S18 N180 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wch B 2.50 BS01 8PH B 1 D80 D84 V175 A176 V179 G180 L183 M207 L211 Q212 N215 C289 D45 D49 V140 A141 V144 G145 L148 M172 L176 Q177 N180 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wch B 2.50 BS02 8PH B 2 F54 Y73 F19 Y38 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wch C 2.50 BS01 8PH C 1 R77 D80 D84 V175 A176 G180 L183 L211 Q212 R42 D45 D49 V140 A141 G145 L148 L176 Q177 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wch D 2.50 BS01 8PH D 1 D80 D84 V175 A176 G180 L183 M207 G208 L211 Y276 C289 D45 D49 V140 A141 G145 L148 M172 G173 L176 Y241 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wch E 2.50 BS01 8PH E 1 R52 S53 F54 G180 L183 M207 Q212 N215 R218 C289 R17 S18 F19 G145 L148 M172 Q177 N180 R183 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wch F 2.50 BS01 8PH F 1 R77 D80 D84 A176 V179 G180 L183 G208 L211 Q212 C289 R42 D45 D49 A141 V144 G145 L148 G173 L176 Q177 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wch F 2.50 BS02 8PH F 2 R52 S53 F54 Y73 L76 P292 R17 S18 F19 Y38 L41 P257 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wci A 2.30 BS01 BH5 A 1 T50 S51 R52 S53 Y73 R77 D80 V175 A176 V179 G180 L183 M207 L211 C289 T15 S16 R17 S18 Y38 R42 D45 V140 A141 V144 G145 L148 M172 L176 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wci B 2.30 BS01 BH5 B 1 T50 S51 R52 S53 F54 Y73 R77 D80 A176 V179 G180 L183 M207 L211 Y276 C289 T15 S16 R17 S18 F19 Y38 R42 D45 A141 V144 G145 L148 M172 L176 Y241 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wci C 2.30 BS01 BH5 C 1 T50 R52 S53 Y73 R77 A176 V179 G180 L183 M207 L211 Y276 C289 T15 R17 S18 Y38 R42 A141 V144 G145 L148 M172 L176 Y241 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wci D 2.30 BS01 BH5 D 1 T50 S51 R52 S53 Y73 R77 D80 V175 V179 G180 L183 M207 L211 Y276 C289 T15 S16 R17 S18 Y38 R42 D45 V140 V144 G145 L148 M172 L176 Y241 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wci E 2.30 BS01 BH5 E 1 T50 S51 R52 S53 L76 R77 D80 V179 G180 L183 M207 L211 C289 T15 S16 R17 S18 L41 R42 D45 V144 G145 L148 M172 L176 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wci F 2.30 BS01 BH5 F 1 T50 S51 R52 Y73 R77 V175 A176 V179 G180 L183 M207 L211 C289 T15 S16 R17 Y38 R42 V140 A141 V144 G145 L148 M172 L176 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcj A 2.20 BS01 E5S A 1 F54 I58 V69 Y73 L76 D80 V175 V179 L183 M207 L211 Y276 F288 C289 Q293 F19 I23 V34 Y38 L41 D45 V140 V144 L148 M172 L176 Y241 F253 C254 Q258 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcj B 2.20 BS01 E5S B 1 F54 I58 V69 Y73 D80 V175 A176 V179 L183 M207 L211 Y276 F288 C289 Q293 F20 I24 V35 Y39 D46 V141 A142 V145 L149 M173 L177 Y242 F254 C255 Q259 2.5.1.21 P37268 24789335 SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQN 3wcj C 2.20 BS01 E5S C 1 F54 I58 V69 Y73 L76 D80 V175 V179 L183 M207 L211 Y276 F288 C289 Q293 F19 I23 V34 Y38 L41 D45 V140 V144 L148 M172 L176 Y241 F253 C254 Q258 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQN 3wcj D 2.20 BS01 E5S D 1 F54 I58 V69 Y73 L76 D80 V175 V179 L183 M207 L211 Y276 F288 C289 Q293 F19 I23 V34 Y38 L41 D45 V140 V144 L148 M172 L176 Y241 F253 C254 Q258 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQN 3wcj E 2.20 BS01 E5S E 1 F54 V69 Y73 D80 V175 A176 V179 L183 M207 L211 Y276 F288 C289 Q293 F19 V34 Y38 D45 V140 A141 V144 L148 M172 L176 Y241 F253 C254 Q258 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQN 3wcj F 2.20 BS01 E5S F 1 F54 V69 Y73 D80 V175 V179 L183 M207 L211 Y276 F288 C289 Q293 F19 V34 Y38 D45 V140 V144 L148 M172 L176 Y241 F253 C254 Q258 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcl A 2.24 BS01 BH3 A 1 S51 R52 S53 F54 Y73 L76 R77 D80 V175 A176 V179 G180 L183 M207 L211 C289 S16 R17 S18 F19 Y38 L41 R42 D45 V140 A141 V144 G145 L148 M172 L176 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcm A 2.06 BS01 ER4 A 1 F54 I58 V69 Y73 L76 R77 D80 A176 V179 G180 L183 F187 M207 L211 Y276 F288 C289 F19 I23 V34 Y38 L41 R42 D45 A141 V144 G145 L148 F152 M172 L176 Y241 F253 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcm B 2.06 BS01 ER4 B 1 F54 I58 V69 Y73 R77 D80 A176 V179 G180 L183 F187 M207 L211 Y276 F288 C289 F21 I25 V36 Y40 R44 D47 A143 V146 G147 L150 F154 M174 L178 Y243 F255 C256 2.5.1.21 P37268 24789335 DSLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wcm C 2.06 BS01 ER4 C 1 F54 V69 Y73 R77 D80 A176 V179 G180 L183 M207 L211 Y276 F288 C289 F19 V34 Y38 R42 D45 A141 V144 G145 L148 M172 L176 Y241 F253 C254 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQN 3wcm D 2.06 BS01 ER4 D 1 F54 I58 V69 Y73 L76 R77 D80 A176 V179 G180 L183 F187 M207 L211 Y276 F288 C289 F18 I22 V33 Y37 L40 R41 D44 A140 V143 G144 L147 F151 M171 L175 Y240 F252 C253 2.5.1.21 P37268 24789335 SSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQN 3wcm E 2.06 BS01 ER4 E 1 F54 V69 Y73 L76 R77 D80 A176 V179 G180 L183 F187 M207 L211 Y276 F288 C289 F18 V33 Y37 L40 R41 D44 A140 V143 G144 L147 F151 M171 L175 Y240 F252 C253 2.5.1.21 P37268 24789335 SSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQN 3wcm F 2.06 BS01 ER4 F 1 V69 Y73 L76 R77 V179 G180 L183 S184 M207 L211 Y276 F288 V34 Y38 L41 R42 V144 G145 L148 S149 M172 L176 Y241 F253 2.5.1.21 P37268 24789335 LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ 3wdh A 1.75 BS01 CA A 1 D282 F283 E288 E308 D273 F274 E279 E299 3.2.1.41 K9L0H1 SFEAYLDELTMITILFPCHVDQKRAPIFFLRDDKKTAYRLTIRSSEKHHSFIKYECLVPFIVELGKRYVVYTEEGWQVPLQVGAVMRTKAFDDLYAYDGNDLGATYDPEKTTFKVWAPTATDVLLKLIHPTTKEETTYVMTREKKGLWTYTVYDDVERFLYTYMTYVNFIWREAVDPYAKSVSVNGTYGVVVDLAKTNIPKPSMSLFISMTDAIIYEMHIRDFTIHHESGVRQKGKYVGLTERGTTGPNGTLTGLSYIKQLGVTHVQLMPVQDFEGVDELQPLKMYNWGYNTVHYNAPEGSYATDPDDPYARIIELKRAIRAFQQEGIRVILDVVYNHVYVRETSSFEHLVPGYYFRYERNGYPSNGTGVGNDLASERKMVKKFIIDSVTYWLKEYGVDGFRFDLMGILDIDTMNDVRRAIDEIDPTVIILGEGWDLATPLPSEKKTTIANAKHTPRIAYFNDRFRDYVKGSTFDIHERGFALGDCSYKEAVIGAIRGSIHLFFSPRQSVNYVECHDNHTLWDKMAVANAHESEYIRRKRQKLATAIVLLSQGIPFLHSGQEFYRTKKGVENSYNSPDEVNQVDWNEKSRWEEDVREIMKLIELRKKHGAFRFLTADQVRRHMKFYDTHPSVIAYQLVDVGVYGPWKQIVVVYHNEEKKAMLPLADGKWKVMFSSELGNVCEQFIEINGIGAWVLIQC 3wjn A 2.60 BS01 FPS A 1 A79 T80 H83 D84 D88 R93 Y116 I142 E146 K170 K235 A79 T80 H83 D84 D88 R93 Y116 I142 E146 K164 K222 2.5.1.- K0BUH0 24895191 MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGGKRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAAFGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMITEENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNANVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMNACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAV 3wjn B 2.60 BS01 FPS A 1 D113 T117 D101 T105 2.5.1.- K0BUH0 24895191 MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGGKRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESFGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITEENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMNACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQR 3wjo A 2.45 BS01 IPE A 1 D84 D88 K170 D84 D88 K161 2.5.1.- K0BUH0 24895191 MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGGKRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAAFGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNNYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNAVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMNACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAV 3wjo A 2.45 BS02 IPE A 2 G44 K45 R48 H77 K170 F207 Q208 G44 K45 R48 H77 K161 F198 Q199 2.5.1.- K0BUH0 24895191 MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGGKRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAAFGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNNYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNAVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMNACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAV 3wlv A 1.75 BS01 AZA A 1 F184 L195 R201 S248 I249 Q250 F177 L188 R194 S241 I242 Q243 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv A 1.75 BS02 CL A 1 N276 G302 Q304 N269 G295 Q297 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv A 1.75 BS03 AZA B 1 Y11 A72 T73 Y4 A65 T66 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv B 1.75 BS01 AZA A 1 Y11 A72 T73 Y4 A65 T66 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv B 1.75 BS02 AZA B 1 F184 L195 R201 S248 I249 Q250 N276 F177 L188 R194 S241 I242 Q243 N269 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv B 1.75 BS03 CL B 1 N276 G302 Q304 N269 G295 Q297 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv C 1.75 BS01 AZA C 1 F184 L195 R201 S248 I249 Q250 N276 F177 L188 R194 S241 I242 Q243 N269 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv C 1.75 BS02 CL C 1 N276 G302 Q304 N269 G295 Q297 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv C 1.75 BS03 AZA D 1 A72 T73 A65 T66 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv D 1.75 BS01 AZA C 1 A72 T73 A65 T66 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv D 1.75 BS02 AZA D 1 F184 L195 R201 S248 I249 Q250 N276 F177 L188 R194 S241 I242 Q243 N269 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wlv D 1.75 BS03 CL D 1 N276 G302 Q304 N269 G295 Q297 1.7.3.3 Q45697 24897238 VMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFGVNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLASYTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTFAVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITEQQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVYLNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETETLSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEIPESEGKVYTEPRPPYGFQCFTVTQ 3wqy A 3.30 BS01 NUC C 1 Y95 R128 E189 P190 W191 N359 A360 G361 Y364 T422 R428 R432 R436 E447 Y449 D450 S451 H452 G453 D727 K781 K845 S872 G873 G874 G875 R876 D878 G882 A883 Y94 R127 E188 P189 W190 N358 A359 G360 Y363 T421 R427 R431 R435 E446 Y448 D449 S450 H451 G452 D726 K780 K844 S871 G872 G873 G874 R875 D877 G881 A882 6.1.1.7 O28029 TLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEHEG 3wqy A 3.30 BS02 A5A A 1 R128 D131 H141 L142 F145 M147 W191 E209 A211 T212 D242 G244 G246 R249 R127 D130 H140 L141 F144 M146 W190 E208 A210 T211 D241 G243 G245 R248 6.1.1.7 O28029 TLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEHEG 3wqy B 3.30 BS01 A5A B 1 R128 D131 H141 L142 F145 M147 W191 E209 V210 A211 T212 V214 D242 T243 G244 G246 R128 D131 H141 L142 F145 M147 W191 E209 V210 A211 T212 V214 D242 T243 G244 G246 6.1.1.7 O28029 MTLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEHE 3wqz A 3.49 BS01 NUC C 1 Y95 E220 N359 A360 G361 Y364 R367 R371 T422 R428 R432 R436 Y449 D450 S451 H452 G453 A481 K482 H484 S485 E723 Q823 E827 K845 F847 G873 G874 G875 R876 D878 Q881 G882 A883 Y94 E219 N358 A359 G360 Y363 R366 R370 T421 R427 R431 R435 Y448 D449 S450 H451 G452 A480 K481 H483 S484 E722 Q822 E826 K844 F846 G872 G873 G874 R875 D877 Q880 G881 A882 6.1.1.7 O28029 TLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEHEG 3wqz A 3.49 BS02 A5A A 1 R128 L142 F145 M147 W191 E209 V210 A211 T212 D242 T243 G244 G246 R249 R127 L141 F144 M146 W190 E208 V209 A210 T211 D241 T242 G243 G245 R248 6.1.1.7 O28029 TLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEHEG 3wqz A 3.49 BS03 ZN A 1 H604 C703 H603 C702 6.1.1.7 O28029 TLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEHEG 3wqz B 3.49 BS01 NUC C 1 L758 V760 F772 L758 V760 F772 6.1.1.7 O28029 MTLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEH 3wqz B 3.49 BS02 A5A B 1 A99 R128 D131 H141 L142 F145 M147 W191 E209 V210 A211 T212 V214 D242 T243 G244 R249 A99 R128 D131 H141 L142 F145 M147 W191 E209 V210 A211 T212 V214 D242 T243 G244 R249 6.1.1.7 O28029 MTLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEH 3wqz B 3.49 BS03 ZN B 1 H600 H604 C703 H600 H604 C703 6.1.1.7 O28029 MTLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEH 4bp0 A 2.24 BS01 ZN A 1 H108 H110 H197 H76 H78 H165 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEMRL 4bp0 A 2.24 BS02 ZN A 2 D112 C216 H258 D80 C184 H221 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEMRL 4bp0 A 2.24 BS03 ZN A 3 H33 D35 H3 D5 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEMRL 4bp0 B 2.24 BS01 ZN B 1 H108 H110 H197 H76 H78 H165 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEMR 4bp0 B 2.24 BS02 ZN B 2 D112 C216 H258 D80 C184 H221 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEMR 4bp0 B 2.24 BS03 ZN B 3 H33 D35 H3 D5 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEMR 4bp0 C 2.24 BS01 ZN C 1 H108 H110 H197 H76 H78 H165 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEM 4bp0 C 2.24 BS02 ZN C 2 D112 C216 H258 D80 C184 H221 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEM 4bp0 D 2.24 BS01 ZN D 1 H108 H110 H197 H76 H78 H165 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEM 4bp0 D 2.24 BS02 ZN D 2 D112 C216 H258 D80 C184 H221 3.5.2.6 Q8G9Q0 SDHVDLPYNLTATKIDSDVFVVTDRDFYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGGCMIKPKELGYLGDANVKAWPDSARRLKKFDAKIVIPGHGEWGGPEMVNKTIKVAEKAVGEM 4bqu A 2.36 BS01 CLR A 1 A6 L14 H17 L21 F22 E23 V26 V29 T31 R43 L45 F63 L86 A88 Y92 L104 S115 W117 A5 L13 H16 L20 F21 E22 V25 V28 T30 R42 L44 F62 L85 A87 Y91 L103 S114 W116 M1MR49 PSMPAINTQTLYLAGHSSKLFERNVGCVKTRYLNQTGDWVTRSLIYVFTFDTEPWVTQAGAFQVKWEPYSPLLRVKASDYVRDNLGAKPDYFIRTYDNDFLLLSDLKEVRSTCSLWVTLKYVDRIPETINRTFYTICPDPVPVPFDERCYPG 4bqu A 2.36 BS02 FUC A 1 R132 Y135 T136 R131 Y134 T135 M1MR49 PSMPAINTQTLYLAGHSSKLFERNVGCVKTRYLNQTGDWVTRSLIYVFTFDTEPWVTQAGAFQVKWEPYSPLLRVKASDYVRDNLGAKPDYFIRTYDNDFLLLSDLKEVRSTCSLWVTLKYVDRIPETINRTFYTICPDPVPVPFDERCYPG 4bqu B 2.36 BS01 CLR B 1 A6 L14 H17 L21 F22 E23 V26 V29 T31 R43 L45 F63 L86 A88 Y92 L104 S115 W117 A5 L13 H16 L20 F21 E22 V25 V28 T30 R42 L44 F62 L85 A87 Y91 L103 S114 W116 M1MR49 PSMPAINTQTLYLAGHSSKLFERNVGCVKTRYLNQTGDWVTRSLIYVFTFDTEPWVTQAGAFQVKWEPYSPLLRVKASDYVRDNLGAKPDYFIRTYDNDFLLLSDLKEVRSTCSLWVTLKYVDRIPETINRTFYTICPDPVPVPFDERC 4bqu B 2.36 BS02 FUC B 1 R132 Y135 T136 R131 Y134 T135 M1MR49 PSMPAINTQTLYLAGHSSKLFERNVGCVKTRYLNQTGDWVTRSLIYVFTFDTEPWVTQAGAFQVKWEPYSPLLRVKASDYVRDNLGAKPDYFIRTYDNDFLLLSDLKEVRSTCSLWVTLKYVDRIPETINRTFYTICPDPVPVPFDERC 4bqv A 1.70 BS01 8PW A 1 Q141 G145 C147 W148 K187 G191 G192 Y193 M194 G260 V285 N286 H287 Y334 Q20 G24 C26 W27 K66 G70 G71 Y72 M73 G139 V164 N165 H166 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4bqv B 1.70 BS01 8PW B 1 Q141 G145 C147 W148 G191 G192 Y193 M194 G260 V285 N286 H287 Y334 Q20 G24 C26 W27 G70 G71 Y72 M73 G139 V164 N165 H166 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4bqv C 1.70 BS01 8PW C 1 Q141 G145 C147 W148 K187 G191 G192 Y193 M194 G260 V285 N286 H287 G288 Y334 Q20 G24 C26 W27 K66 G70 G71 Y72 M73 G139 V164 N165 H166 G167 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4bqv D 1.70 BS01 8PW D 1 Q141 G145 C147 W148 K187 G191 G192 Y193 M194 G260 V285 N286 H287 Y334 Q20 G24 C26 W27 K66 G70 G71 Y72 M73 G139 V164 N165 H166 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4bqv E 1.70 BS01 8PW E 1 Q141 G145 C147 W148 G191 G192 Y193 M194 G260 V285 N286 H287 Y334 Q20 G24 C26 W27 G70 G71 Y72 M73 G139 V164 N165 H166 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4bqv F 1.70 BS01 8PW F 1 Q141 G145 C147 W148 G191 G192 Y193 M194 G260 V285 N286 H287 Y334 Q20 G24 C26 W27 G70 G71 Y72 M73 G139 V164 N165 H166 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4bqv G 1.70 BS01 8PW G 1 Q141 G145 A146 C147 W148 G191 G192 Y193 G260 V285 N286 H287 Y334 Q20 G24 A25 C26 W27 G70 G71 Y72 G139 V164 N165 H166 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4bqv H 1.70 BS01 8PW H 1 Q141 G145 C147 W148 G191 G192 Y193 G260 V285 N286 H287 Y334 Q20 G24 C26 W27 G70 G71 Y72 G139 V164 N165 H166 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4brb A 2.55 BS01 78N A 1 Q33 C41 I105 W112 Q28 C36 I100 W107 2.7.1.107 P0ABN1 GFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4brb A 2.55 BS02 78N A 2 R22 W25 I26 V38 M63 M66 R17 W20 I21 V33 M58 M61 2.7.1.107 P0ABN1 GFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4brb A 2.55 BS03 78N A 3 W25 L39 L40 W20 L34 L35 2.7.1.107 P0ABN1 GFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4brb A 2.55 BS04 78N A 4 V42 A46 L48 R55 V37 A41 L43 R50 2.7.1.107 P0ABN1 GFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4brb B 2.55 BS01 78N A 5 I110 I114 I88 I92 2.7.1.107 P0ABN1 AAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brb B 2.55 BS02 78N A 6 I110 I114 W117 I88 I92 W95 2.7.1.107 P0ABN1 AAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brb B 2.55 BS03 78N B 1 A46 A52 R55 A24 A30 R33 2.7.1.107 P0ABN1 AAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brb B 2.55 BS04 78N B 2 Q33 E34 E69 I105 A108 W112 Q11 E12 E47 I83 A86 W90 2.7.1.107 P0ABN1 AAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brb C 2.55 BS01 78N B 1 I110 I114 S118 I82 I86 S90 2.7.1.107 P0ABN1 AAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brb C 2.55 BS02 78N C 1 V42 A46 R55 M63 V14 A18 R27 M35 2.7.1.107 P0ABN1 AAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brb D 2.55 BS01 ZN D 1 E28 E76 E15 E63 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brb D 2.55 BS02 78N D 1 W47 D49 F120 W34 D36 F107 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brb D 2.55 BS03 78N D 2 L102 I105 V109 I110 A113 I114 L89 I92 V96 I97 A100 I101 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brr B 2.44 BS01 79M B 1 A52 R55 A30 R33 2.7.1.107 P0ABN1 AAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHF 4brr C 2.44 BS01 79M B 1 I110 I114 I79 I83 2.7.1.107 P0ABN1 RQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brr D 2.44 BS01 ZN D 1 E28 E76 E15 E63 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brr D 2.44 BS02 79M D 1 W47 L48 D49 F120 W34 L35 D36 F107 2.7.1.107 P0ABN1 AGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYHELSGRAKDLGSAAVLIAIIDAVITWAILLWSHFG 4brv A 2.05 BS01 FE A 1 H25 H50 H56 C109 H112 H25 H50 H56 C109 H112 A8AC72 MKSFGELIYTPDRAEGEAISKAATHTPKIEAPEKVKADQPFQVRVSVGPHPNEAAHSIRWIELYFYEEGRPFNPVMLGRVAFEPGYAEPDVTFTLKLKKSGVLYAISYCNLHGLWEARKEIKVE 4brv B 2.05 BS01 FE B 1 H25 H50 H56 C109 H112 H25 H50 H56 C109 H112 A8AC72 MKSFGELIYTPDRAEGEAISKAATHTPKIEAPEKVKADQPFQVRVSVGPHPNEAAHSIRWIELYFYEEGRPFNPVMLGRVAFEPGYAEPDVTFTLKLKKSGVLYAISYCNLHGLWEARKEIKVE 4brv C 2.05 BS01 FE C 1 H25 H50 H56 C109 H112 H25 H50 H56 C109 H112 A8AC72 MKSFGELIYTPDRAEGEAISKAATHTPKIEAPEKVKADQPFQVRVSVGPHPNEAAHSIRWIELYFYEEGRPFNPVMLGRVAFEPGYAEPDVTFTLKLKKSGVLYAISYCNLHGLWEARKEIKVE 4brv D 2.05 BS01 FE D 1 H25 H50 H56 C109 H112 H25 H50 H56 C109 H112 A8AC72 MKSFGELIYTPDRAEGEAISKAATHTPKIEAPEKVKADQPFQVRVSVGPHPNEAAHSIRWIELYFYEEGRPFNPVMLGRVAFEPGYAEPDVTFTLKLKKSGVLYAISYCNLHGLWEARKEIKVE 4bs6 A 1.20 BS01 JG7 A 1 Q141 G145 C147 W148 K187 G191 G192 Y193 M194 G260 V285 N286 H287 G288 Y334 Q20 G24 C26 W27 K66 G70 G71 Y72 M73 G139 V164 N165 H166 G167 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4bs6 B 1.20 BS01 JG7 B 1 Q141 G145 C147 W148 K187 G191 G192 Y193 M194 G260 V285 N286 H287 G288 Y334 Q20 G24 C26 W27 K66 G70 G71 Y72 M73 G139 V164 N165 H166 G167 Y213 3.4.22.27 O70370 TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 4bya A BS01 CA A 1 D20 D22 N24 Y26 E31 D20 D22 N24 Y26 E31 F2Z4K8 SLMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQHMTAK 4bya A BS02 CA A 2 D56 D58 D60 Q62 E67 D56 D58 D60 Q62 E67 F2Z4K8 SLMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQHMTAK 4cc5 A 1.88 BS01 L5V A 1 L82 E110 L111 Y219 V281 K283 L81 E109 L110 Y218 V280 K282 6.5.1.2 Q9AIU7 24900632 ADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEHPEYKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFP 4cc6 A 2.01 BS01 L5Y A 1 L80 L82 E110 L111 K112 I113 R133 E167 Y219 K283 P300 A303 L79 L81 E109 L110 K111 I112 R132 E166 Y218 K282 P299 A302 6.5.1.2 Q9AIU7 24900632 ADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEHPEYKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFP 4cik A 1.78 BS01 XO3 A 1 R35 D55 D57 W62 Y64 R71 Y72 R36 D56 D58 W63 Y65 R72 Y73 3.4.21.7 P00747 24900876 SECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILEC 4cku A 1.85 BS01 P2F A 1 I14 I32 D34 G36 Y77 V78 S79 F111 I123 Y192 D214 G216 T217 S218 I290 L292 I300 I12 I30 D32 G34 Y75 V76 S77 F109 I121 Y190 D212 G214 T215 S216 I284 L286 I294 3.4.23.39 P46925 24900843 NDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4cku B 1.85 BS01 P2F B 1 I14 I32 D34 G36 Y77 V78 S79 F111 I123 Y192 D214 G216 T217 S218 I290 L292 F294 I300 I12 I30 D32 G34 Y75 V76 S77 F109 I121 Y190 D212 G214 T215 S216 I288 L290 F292 I298 3.4.23.39 P46925 24900843 NDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4cku C 1.85 BS01 P2F C 1 M15 I32 D34 G36 Y77 V78 S79 F111 I123 Y192 D214 G216 T217 S218 I290 L292 I300 M14 I31 D33 G35 Y76 V77 S78 F110 I122 Y191 D213 G215 T216 S217 I283 L285 I293 3.4.23.39 P46925 24900843 SNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHILCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4cku D 1.85 BS01 P2F D 1 M15 I32 D34 G36 Y77 V78 S79 F111 T114 I123 Y192 D214 G216 T217 S218 I300 M14 I31 D33 G35 Y76 V77 S78 F110 T113 I122 Y191 D213 G215 T216 S217 I294 3.4.23.39 P46925 24900843 SNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4cku E 1.85 BS01 P2F E 1 M15 I32 D34 G36 Y77 V78 S79 F111 I123 Y192 D214 G216 T217 S218 I290 L292 I300 M14 I31 D33 G35 Y76 V77 S78 F110 I122 Y191 D213 G215 T216 S217 I283 L285 I293 3.4.23.39 P46925 24900843 SNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4cku F 1.85 BS01 P2F F 1 M15 I32 D34 G36 S37 Y77 V78 S79 F111 I123 Y192 D214 G216 T217 S218 I290 L292 I300 M15 I32 D34 G36 S37 Y77 V78 S79 F111 I123 Y192 D214 G216 T217 S218 I290 L292 I300 3.4.23.39 P46925 24900843 SSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4cns A 2.40 BS01 MG A 1 D128 G464 G466 D117 G453 G455 Q14195 24914979 MTSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMA 4cns A 2.40 BS02 MG A 2 K254 I279 T303 K243 I268 T292 Q14195 24914979 MTSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMA 4cns B 2.40 BS01 MG B 1 D128 G464 G466 D117 G453 G455 Q14195 24914979 MTSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKM 4cns C 2.40 BS01 MG C 1 D128 G464 G466 D118 G454 G456 Q14195 24914979 SMTSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKM 4cns D 2.40 BS01 MG D 1 D128 G464 G466 D118 G454 G456 Q14195 24914979 SMTSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMA 4cxt A 2.66 BS01 SXJ A 1 Y85 H129 K131 R135 G148 K150 C151 H154 Y37 H81 K83 R87 G100 K102 C103 H106 Q14145 24896564 NRTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACADFLVQQLD 4d25 A 1.90 BS01 NUC D 1 P265 T266 R267 G293 G294 V297 T314 G316 R317 D320 R324 F348 E439 T440 K441 H462 G463 R470 T488 A489 V490 P129 T130 R131 G157 G158 V161 T178 G180 R181 D184 R188 F212 E303 T304 K305 H326 G327 R334 T352 A353 V354 O01378 24910301 YVPPEPTNDETEIFSSTISSGINFDKFDHIAVKVSGENPPRPIESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPIINMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLKVAVAYGGTAVRHQGDNIARGCHILVATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDMGFMPSIEKMMLHPTMVETTKRQTLMFSATFPEDIQHLAGRFLNNYLFVAVGIVGGASTDVEQIFIEVTKYEKRNSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKAVSFYDSDQDLALVADLSKILRQADQSVPDFLK 4d25 A 1.90 BS02 ANP A 1 T153 I154 F160 Y200 K202 Q207 T226 G227 S228 G229 K230 T231 Q339 G494 D496 R521 R524 V525 T17 I18 F24 Y64 K66 Q71 T90 G91 S92 G93 K94 T95 Q203 G358 D360 R385 R388 V389 O01378 24910301 YVPPEPTNDETEIFSSTISSGINFDKFDHIAVKVSGENPPRPIESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPIINMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLKVAVAYGGTAVRHQGDNIARGCHILVATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDMGFMPSIEKMMLHPTMVETTKRQTLMFSATFPEDIQHLAGRFLNNYLFVAVGIVGGASTDVEQIFIEVTKYEKRNSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKAVSFYDSDQDLALVADLSKILRQADQSVPDFLK 4d26 A 2.10 BS01 NUC D 1 V135 P265 T266 R267 G293 G294 V297 T314 P315 G316 R317 D320 F348 E439 T440 K441 H462 G463 R470 T488 A489 V490 V2 P132 T133 R134 G160 G161 V164 T181 P182 G183 R184 D187 F215 E306 T307 K308 H329 G330 R337 T355 A356 V357 O01378 24910301 GVTYVPPEPTNDETEIFSSTISSGINFDKFDHIAVKVSGENPPRPIESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPIINMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLKVAVAYGGTAVRHQGDNIARGCHILVATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDMGFMPSIEKMMLHPTMVETTKRQTLMFSATFPEDIQHLAGRFLNNYLFVAVGIVGGASTDVEQIFIEVTKYEKRNSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKAVSFYDSDQDLALVADLSKILRQADQSVPDFLK 4d26 A 2.10 BS02 ADP A 1 T153 I154 F160 F182 Y200 K202 P203 Q207 G227 S228 G229 K230 T231 D496 R524 V525 T20 I21 F27 F49 Y67 K69 P70 Q74 G94 S95 G96 K97 T98 D363 R391 V392 O01378 24910301 GVTYVPPEPTNDETEIFSSTISSGINFDKFDHIAVKVSGENPPRPIESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPIINMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLKVAVAYGGTAVRHQGDNIARGCHILVATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDMGFMPSIEKMMLHPTMVETTKRQTLMFSATFPEDIQHLAGRFLNNYLFVAVGIVGGASTDVEQIFIEVTKYEKRNSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKAVSFYDSDQDLALVADLSKILRQADQSVPDFLK 4d26 A 2.10 BS03 MG A 1 K230 Q339 K97 Q206 O01378 24910301 GVTYVPPEPTNDETEIFSSTISSGINFDKFDHIAVKVSGENPPRPIESFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPIINMLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLKVAVAYGGTAVRHQGDNIARGCHILVATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDMGFMPSIEKMMLHPTMVETTKRQTLMFSATFPEDIQHLAGRFLNNYLFVAVGIVGGASTDVEQIFIEVTKYEKRNSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKAVSFYDSDQDLALVADLSKILRQADQSVPDFLK 4k2f A 1.99 BS01 A08 B 1 T166 L169 T138 L141 3.5.1.97 Q9I194 24824984 TGLAADIRWTAYGVPHIRAKDERGLGYGIGYAYARDNACLLAEEIVTARGERARYFGSEGKSSAELDNLPSDIFYAWLNQPEALQAFWQAQTPAVRQLLEGYAAGFNRFLREADGKTTSCLGQPWLRAIATDDLLRLTRRLLVEGGVGQFADALVAAAPPGAEK 4k2f B 1.99 BS01 A08 B 1 F240 F248 L266 L269 H284 V374 W378 P401 W402 V403 F24 F32 L50 L53 H68 V158 W162 P185 W186 V187 3.5.1.97 Q9I194 24824984 SNAIAVGSERSADGKGMLLANPHFPWNGAMRFYQMHLTIPGRLDVMGASLPGLPVVNIGFSRHLAWTHTVDTSSHFTLYRLALDPKDPRRYLVDGRSLPLEEKSVAIEVRGADGKLSRVEHKVYQSIYGPLVVWPGKLDWNRSEAYALRDANLENTRVLQQWYSINQASDVADLRRRVEALQGIPWVNTLAADEQGNALYMNQSVVPYLKPELIPACAIPQLVAEGLPALQGQDSRCAWSRDPAAAQAGITPAAQLPVLLRRDFVQNSNDSAWLTNPASPLQGFSPLVSQEKPIGPRARYALSRLQGKQPLEAKTLEEMVTANHVFSADQVLPDLLRLCRDNQGEKSLARACAALAQWDRGANLDSGSGFVYFQRFMQRFAELDGAWKEPFDAQRPLDTPQGIALDRPQVATQVRQALADAAAEVEKSGIPDGARWGDLQVSTRGQERIAIPGGDGHFGVYNAIQSVRKGDHLEVVGGTSYIQLVTFPEEGPKARGLLAFSQSSDPRSPHYRDQTELFSRQQWQTLPFSDRQIDADPQLQRLSIRE 4k2g A 2.30 BS01 1OQ B 1 T166 L169 L170 T138 L141 L142 3.5.1.97 Q9I194 24824984 TGLAADIRWTAYGVPHIRAKDERGLGYGIGYAYARDNACLLAEEIVTARGERARYFGSEGKSSAELDNLPSDIFYAWLNQPEALQAFWQAQTPAVRQLLEGYAAGFNRFLREADGKTTSCLGQPWLRAIATDDLLRLTRRLLVEGGVGQFADALVAAAPPGAEK 4k2g B 2.30 BS01 1OQ B 1 F240 M246 L266 L269 N273 H284 V374 W378 P401 W402 V403 F24 M30 L50 L53 N57 H68 V158 W162 P185 W186 V187 3.5.1.97 Q9I194 24824984 SNAIAVGSERSADGKGMLLANPHFPWNGAMRFYQMHLTIPGRLDVMGASLPGLPVVNIGFSRHLAWTHTVDTSSHFTLYRLALDPKDPRRYLVDGRSLPLEEKSVAIEVRGADGKLSRVEHKVYQSIYGPLVVWPGKLDWNRSEAYALRDANLENTRVLQQWYSINQASDVADLRRRVEALQGIPWVNTLAADEQGNALYMNQSVVPYLKPELIPACAIPQLVAEGLPALQGQDSRCAWSRDPAAAQAGITPAAQLPVLLRRDFVQNSNDSAWLTNPASPLQGFSPLVSQEKPIGPRARYALSRLQGKQPLEAKTLEEMVTANHVFSADQVLPDLLRLCRDNQGEKSLARACAALAQWDRGANLDSGSGFVYFQRFMQRFAELDGAWKEPFDAQRPLDTPQGIALDRPQVATQVRQALADAAAEVEKSGIPDGARWGDLQVSTRGQERIAIPGGDGHFGVYNAIQSVRKGDHLEVVGGTSYIQLVTFPEEGPKARGLLAFSQSSDPRSPHYRDQTELFSRQQWQTLPFSDRQIDADPQLQRLSIRE 4klc A 2.40 BS01 FES A 1 C196 R272 S402 C403 C406 C411 C132 R208 S338 C339 C342 C347 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPAIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIDTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4klc A 2.40 BS02 HEM A 1 M76 G77 G78 P79 L92 F93 L98 Y123 S197 T198 H263 L265 P266 W310 F337 H341 I342 D343 M12 G13 G14 P15 L28 F29 L34 Y59 S133 T134 H199 L201 P202 W246 F273 H277 I278 D279 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPAIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIDTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4klc B 2.40 BS01 FES B 1 C196 R272 S402 C403 C406 C411 C132 R208 S338 C339 C342 C347 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPAIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIDTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4klc B 2.40 BS02 HEM B 1 F88 L92 F93 L98 R115 I119 Y123 Y191 S197 T198 H263 L265 P266 Y276 V305 W310 F337 H341 I342 F24 L28 F29 L34 R51 I55 Y59 Y127 S133 T134 H199 L201 P202 Y212 V241 W246 F273 H277 I278 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPAIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIDTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4klr A 2.18 BS01 BCT A 1 M76 L98 Y165 M12 L34 Y101 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIQTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4klr A 2.18 BS02 HEM A 1 M76 L89 L92 F93 L98 R115 I119 Y123 S197 T198 H263 L265 P266 Y276 V305 W310 A336 F337 H341 I342 M12 L25 L28 F29 L34 R51 I55 Y59 S133 T134 H199 L201 P202 Y212 V241 W246 A272 F273 H277 I278 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIQTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4klr A 2.18 BS03 FES A 1 C196 R272 S402 C403 C406 C411 C132 R208 S338 C339 C342 C347 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIQTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4klr B 2.18 BS01 BCT B 1 M76 L98 Y165 M12 L34 Y101 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIQTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4klr B 2.18 BS02 HEM B 1 M76 L89 L92 F93 L98 R115 I119 Y123 Y191 S197 T198 H263 L265 P266 Y276 W310 A336 F337 H341 I342 M12 L25 L28 F29 L34 R51 I55 Y59 Y127 S133 T134 H199 L201 P202 Y212 W246 A272 F273 H277 I278 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIQTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4klr B 2.18 BS03 FES B 1 C196 R272 S402 C403 C406 C411 C132 R208 S338 C339 C342 C347 4.99.1.1 P22830 RKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIQTLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4l6b A 1.37 BS01 1VS A 1 D33 D35 G37 Y79 G80 D81 S83 F116 D119 I122 L125 F194 I217 D219 G221 T222 I300 I304 D33 D35 G37 Y79 G80 D81 S83 F116 D119 I122 L125 F194 I217 D219 G221 T222 I300 I304 3.4.23.22 P11838 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 4l7v A 2.05 BS01 SAH A 1 I82 G83 T84 G85 S86 Y88 Q89 V103 E104 R105 I106 L109 D131 G132 W133 T148 V200 P201 L202 V203 I60 G61 T62 G63 S64 Y66 Q67 V81 E82 R83 I84 L87 D109 G110 W111 T126 V178 P179 L180 V181 2.1.1.77 A5F9C1 NPKADRLIQFLTEQGITSPQVLAAIHALPREFFVAPSQPYIVAKMTELLALTPETKVLEIGTGSGYQTAVLAKLVNHVFTVERIKTLQWDAKRRLKQLDIYNVSTKHGDGWQGWPARGPFDAILVTAAAAKVPQSLLDQLAEGGRMVIPVGEDEQYLYKIVRQGGQFISERVEAVRFVPLVAGDLA 4l8z A 1.70 BS01 RL1 A 1 N51 A55 K58 D93 I96 G97 M98 L103 L107 F138 V150 W162 T184 N35 A39 K42 D77 I80 G81 M82 L87 L91 F122 V134 W146 T168 P07900 24751441 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 4l90 A 2.00 BS01 RL3 A 1 N51 A55 D93 I96 G97 M98 L103 L107 F138 V150 W162 T184 N35 A39 D77 I80 G81 M82 L87 L91 F122 V134 W146 T168 P07900 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 4l91 A 1.75 BS01 X29 A 1 N51 A55 D93 M98 L103 F138 V150 W162 T184 N35 A39 D77 M82 L87 F122 V134 W146 T168 P07900 24751441 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 4l93 A 1.84 BS01 S36 A 1 N51 D54 A55 D93 I96 G97 M98 L107 F138 T184 V186 N35 D38 A39 D77 I80 G81 M82 L91 F122 T168 V170 P07900 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 4l93 B 1.84 BS01 S36 B 1 N51 D54 A55 D93 I96 G97 M98 F138 T184 V186 N35 D38 A39 D77 I80 G81 M82 F122 T168 V170 P07900 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 4l94 A 1.65 BS01 S46 A 1 L48 N51 A55 K58 D93 I96 G97 M98 T184 V186 L32 N35 A39 K42 D77 I80 G81 M82 T168 V170 P07900 24751441 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 4len A 1.50 BS01 2GK A 1 C69 S70 K73 N104 Y105 S130 N132 E166 N170 T235 G236 S237 C44 S45 K48 N79 Y80 S105 N107 E141 N145 T210 G211 S212 3.5.2.6 Q9L5C8 24882105 QTSAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAEGL 4len B 1.50 BS01 2GK B 1 C69 S70 K73 N104 Y105 S130 N132 E166 N170 T216 K234 T235 G236 S237 C42 S43 K46 N77 Y78 S103 N105 E139 N143 T189 K207 T208 G209 S210 3.5.2.6 Q9L5C8 24882105 SAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAEGL 4liq E 2.60 BS01 FUC E 1 G333 F334 R384 G306 F307 R353 2.7.10.1 P07333 24898549 IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEKLANATTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIP 4liq E 2.60 BS02 FUC E 2 Q426 N428 H488 N489 Q395 N397 H457 N458 2.7.10.1 P07333 24898549 IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEKLANATTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIP 4lm6 A 1.70 BS01 DBV B 1 Y59 K62 Y59 K62 KMATDSKAPLIELFDERDGCKGPAANKASDVGEPGLCVKVSMQKVAMNAAAAKSVATNYMRK 4lm6 B 1.70 BS01 DBV B 1 C50 D54 S57 G58 C61 E62 R129 I133 A136 T137 F141 A146 Q147 Q148 K149 C50 D54 S57 G58 C61 E62 R129 I133 A136 T137 F141 A146 Q147 Q148 K149 MLDAFSKVITSADGKAAYVGGADLQALKKFVSDGNKRMDAVNAIVSNASCIVSDAVSGMVCENPALIAPNGGVYSNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARAVAIMKATVNGFINNTAQQKKLSTPAGDCSALASEAGGYFDKVSSALA 4lm6 C 1.70 BS01 DBV D 1 Y59 K62 Y59 K62 KMATDSKAPLIELFDERDGCKGPAANKASDVGEPGLCVKVSMQKVAMNAAAAKSVATNYMRK 4lm6 D 1.70 BS01 DBV D 1 C50 D54 S57 G58 C61 E62 R129 I133 A136 T137 F141 A146 Q148 K149 C48 D52 S55 G56 C59 E60 R127 I131 A134 T135 F139 A144 Q146 K147 DAFSKVITSADGKAAYVGGADLQALKKFVSDGNKRMDAVNAIVSNASCIVSDAVSGMVCENPALIAPNGGVYSNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARAVAIMKATVNGFINNTAQQKKLSTPAGDCSALASEAGGYFDKVSSALA 4lms A 1.35 BS01 M1V A 1 F13 A15 C18 A20 N22 A23 Q24 Y25 D35 D36 Q37 C38 K40 F13 A15 C18 A20 N22 A23 Q24 Y25 D35 D36 Q37 C38 K40 RDAQLRAPIVEIFDARGCDAKNAQYTGPKSNDMNDDQCVKVSMQKITVSEATAAKKLQEFIGGKATAINVPIISSMTKKY 4lms A 1.35 BS02 DBV B 1 G63 K64 A65 T66 A67 V70 P71 I72 I73 S74 G63 K64 A65 T66 A67 V70 P71 I72 I73 S74 RDAQLRAPIVEIFDARGCDAKNAQYTGPKSNDMNDDQCVKVSMQKITVSEATAAKKLQEFIGGKATAINVPIISSMTKKY 4lms A 1.35 BS03 M1V C 1 I61 M76 T77 K78 I61 M76 T77 K78 RDAQLRAPIVEIFDARGCDAKNAQYTGPKSNDMNDDQCVKVSMQKITVSEATAAKKLQEFIGGKATAINVPIISSMTKKY 4lms A 1.35 BS04 DBV D 1 A67 I68 A67 I68 RDAQLRAPIVEIFDARGCDAKNAQYTGPKSNDMNDDQCVKVSMQKITVSEATAAKKLQEFIGGKATAINVPIISSMTKKY 4lms B 1.35 BS01 M1V A 1 Y18 G20 Y4 G6 KAAYVGGADLQALKKFVSEGNKRLDAVNAIVSNASCIVSDAVSGMICENPALISPSGNCYTNRRMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLGGLKETYASLGVPAAGNARAVGIMKATCVAFINNTSNQKKLSTPAGDCSALASECAGYFDKVTSAL 4lms B 1.35 BS02 DBV B 1 C50 I51 D54 S57 G58 C61 I133 A136 T137 A140 F141 S146 N147 Q148 C36 I37 D40 S43 G44 C47 I119 A122 T123 A126 F127 S132 N133 Q134 KAAYVGGADLQALKKFVSEGNKRLDAVNAIVSNASCIVSDAVSGMICENPALISPSGNCYTNRRMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLGGLKETYASLGVPAAGNARAVGIMKATCVAFINNTSNQKKLSTPAGDCSALASECAGYFDKVTSAL 4lms B 1.35 BS03 M1V C 1 P64 A65 I67 S68 P50 A51 I53 S54 KAAYVGGADLQALKKFVSEGNKRLDAVNAIVSNASCIVSDAVSGMICENPALISPSGNCYTNRRMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLGGLKETYASLGVPAAGNARAVGIMKATCVAFINNTSNQKKLSTPAGDCSALASECAGYFDKVTSAL 4lms B 1.35 BS04 DBV D 1 N147 Q148 K150 N133 Q134 K136 KAAYVGGADLQALKKFVSEGNKRLDAVNAIVSNASCIVSDAVSGMICENPALISPSGNCYTNRRMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLGGLKETYASLGVPAAGNARAVGIMKATCVAFINNTSNQKKLSTPAGDCSALASECAGYFDKVTSAL 4lms C 1.35 BS01 M1V A 1 L63 L66 L63 L66 KDAQLRAPVVTIFDARGCKDHANKEYTGPKAGNAENDECCVKVQMTPIKVADDAAALVLKECLSELKG 4lms C 1.35 BS02 M1V C 1 F13 C18 D20 H21 N23 K24 E25 Y26 D37 E38 C39 C40 K42 F13 C18 D20 H21 N23 K24 E25 Y26 D37 E38 C39 C40 K42 KDAQLRAPVVTIFDARGCKDHANKEYTGPKAGNAENDECCVKVQMTPIKVADDAAALVLKECLSELKG 4lms C 1.35 BS03 DBV D 1 E65 K67 E65 K67 KDAQLRAPVVTIFDARGCKDHANKEYTGPKAGNAENDECCVKVQMTPIKVADDAAALVLKECLSELKG 4lms D 1.35 BS01 M1V A 1 A65 I67 A52 I54 SKAAYVGGADLQALKKFVSEGNKRLDAVNAIVSNASCIVSDAVSGMICENPALISPSGNCYTNRRMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLGGLKETYASLGVPAAGNARAVGIMKATCVAFINNTSNQKKLSTPAGDCSALASECAGYFDKVTSAL 4lms D 1.35 BS02 M1V C 1 Y18 G20 Y5 G7 SKAAYVGGADLQALKKFVSEGNKRLDAVNAIVSNASCIVSDAVSGMICENPALISPSGNCYTNRRMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLGGLKETYASLGVPAAGNARAVGIMKATCVAFINNTSNQKKLSTPAGDCSALASECAGYFDKVTSAL 4lms D 1.35 BS03 DBV D 1 C50 I51 D54 S57 G58 C61 E62 R129 I133 A136 T137 A140 F141 C37 I38 D41 S44 G45 C48 E49 R116 I120 A123 T124 A127 F128 SKAAYVGGADLQALKKFVSEGNKRLDAVNAIVSNASCIVSDAVSGMICENPALISPSGNCYTNRRMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLGGLKETYASLGVPAAGNARAVGIMKATCVAFINNTSNQKKLSTPAGDCSALASECAGYFDKVTSAL 4lmx A 1.80 BS01 PEB A 1 F14 E16 C20 K21 A22 T25 Q26 K27 A28 G33 F34 C35 K37 F14 E16 C20 K21 A22 T25 Q26 K27 A28 G33 F34 C35 K37 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLL 4lmx A 1.80 BS02 DBV B 1 Y57 N58 K60 L61 Y57 N58 K60 L61 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLL 4lmx A 1.80 BS03 PEB B 1 V13 F14 R17 F34 C35 V13 F14 R17 F34 C35 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLL 4lmx A 1.80 BS04 PEB B 2 M2 K4 D5 S6 M2 K4 D5 S6 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLL 4lmx A 1.80 BS05 PEB C 1 K44 M45 N46 A47 K44 M45 N46 A47 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLL 4lmx B 1.80 BS01 DBV B 1 C50 I51 D54 S57 G58 C61 E62 R129 I133 A136 T137 F141 N145 S146 Q148 K149 C50 I51 D54 S57 G58 C61 E62 R129 I133 A136 T137 F141 N145 S146 Q148 K149 MLDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx B 1.80 BS02 PEB B 1 K28 N35 K36 M38 D39 S40 I142 N144 T153 P154 G156 C158 K28 N35 K36 M38 D39 S40 I142 N144 T153 P154 G156 C158 MLDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx B 1.80 BS03 PEB B 3 M59 G72 V73 K78 A81 C82 R84 D85 I88 R108 L113 L120 V122 P123 G126 N127 M59 G72 V73 K78 A81 C82 R84 D85 I88 R108 L113 L120 V122 P123 G126 N127 MLDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx C 1.80 BS01 PEB A 1 F45 N46 A47 F45 N46 A47 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIGFNAAEAASVTKNYGIKRFGAKS 4lmx C 1.80 BS02 PEB C 1 F14 E16 C20 K21 A22 T25 Q26 K27 A28 G33 F34 C35 K37 F14 E16 C20 K21 A22 T25 Q26 K27 A28 G33 F34 C35 K37 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIGFNAAEAASVTKNYGIKRFGAKS 4lmx C 1.80 BS03 DBV D 1 Y57 G58 K60 F62 G63 A64 K65 S66 Y57 G58 K60 F62 G63 A64 K65 S66 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIGFNAAEAASVTKNYGIKRFGAKS 4lmx C 1.80 BS04 PEB D 1 V13 F14 R17 F34 V13 F14 R17 F34 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIGFNAAEAASVTKNYGIKRFGAKS 4lmx C 1.80 BS05 PEB D 2 M2 K4 D5 S6 K7 M2 K4 D5 S6 K7 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIGFNAAEAASVTKNYGIKRFGAKS 4lmx D 1.80 BS01 PEB A 1 R77 A80 R75 A78 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx D 1.80 BS02 DBV D 1 C50 I51 D54 S57 G58 C61 R129 I133 A136 T137 F141 S146 Q148 K149 C48 I49 D52 S55 G56 C59 R127 I131 A134 T135 F139 S144 Q146 K147 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx D 1.80 BS03 PEB D 1 K28 N35 K36 M38 D39 S40 I142 N144 T153 P154 G156 C158 K26 N33 K34 M36 D37 S38 I140 N142 T151 P152 G154 C156 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx D 1.80 BS04 PEB D 3 M59 G72 V73 K78 A81 C82 R84 D85 I88 R108 L113 Y117 L120 V122 P123 G126 N127 M57 G70 V71 K76 A79 C80 R82 D83 I86 R106 L111 Y115 L118 V120 P121 G124 N125 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx E 1.80 BS01 PEB E 1 F14 E16 C20 A22 T25 Q26 K27 A28 G33 F34 C35 K37 F14 E16 C20 A22 T25 Q26 K27 A28 G33 F34 C35 K37 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx E 1.80 BS02 DBV F 1 Y57 N58 K60 L61 G63 A64 K65 S66 Y57 N58 K60 L61 G63 A64 K65 S66 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx E 1.80 BS03 PEB F 1 V13 F14 R17 F34 V13 F14 R17 F34 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx E 1.80 BS04 PEB F 2 M2 K4 D5 S6 M2 K4 D5 S6 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx E 1.80 BS05 PEB G 1 K44 M45 A47 K44 M45 A47 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx F 1.80 BS01 DBV F 1 C50 I51 D54 S57 G58 C61 E62 R129 I133 A136 T137 F141 S146 Q148 K149 C49 I50 D53 S56 G57 C60 E61 R128 I132 A135 T136 F140 S145 Q147 K148 LDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx F 1.80 BS02 PEB F 1 K28 N35 K36 M38 D39 S40 I142 T153 P154 G156 C158 K27 N34 K35 M37 D38 S39 I141 T152 P153 G155 C157 LDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx F 1.80 BS03 PEB F 3 M59 G72 V73 R77 K78 A81 C82 R84 D85 I88 R108 L113 T116 L120 V122 P123 G126 N127 M58 G71 V72 R76 K77 A80 C81 R83 D84 I87 R107 L112 T115 L119 V121 P122 G125 N126 LDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx F 1.80 BS04 PEB G 1 R77 A80 R76 A79 LDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx G 1.80 BS01 PEB E 1 K44 M45 N46 A47 K44 M45 N46 A47 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAK 4lmx G 1.80 BS02 PEB G 1 F14 E16 C20 K21 A22 T25 Q26 K27 A28 G33 F34 C35 K37 F14 E16 C20 K21 A22 T25 Q26 K27 A28 G33 F34 C35 K37 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAK 4lmx G 1.80 BS03 DBV H 1 Y57 N58 K60 L61 A64 K65 Y57 N58 K60 L61 A64 K65 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAK 4lmx G 1.80 BS04 PEB H 1 V13 F14 R17 F34 V13 F14 R17 F34 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAK 4lmx G 1.80 BS05 PEB H 2 M2 K4 D5 S6 K7 M2 K4 D5 S6 K7 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAK 4lmx H 1.80 BS01 DBV H 1 C50 I51 D54 S57 G58 C61 R129 I133 A136 T137 F141 S146 Q148 K149 C49 I50 D53 S56 G57 C60 R128 I132 A135 T136 F140 S145 Q147 K148 LDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx H 1.80 BS02 PEB H 1 K28 N35 K36 M38 D39 S40 I142 N144 T153 P154 A155 G156 C158 K27 N34 K35 M37 D38 S39 I141 N143 T152 P153 A154 G155 C157 LDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx H 1.80 BS03 PEB H 3 M59 G72 V73 K78 A81 C82 R84 D85 I88 R108 L113 T116 L120 V122 P123 G126 N127 M58 G71 V72 K77 A80 C81 R83 D84 I87 R107 L112 T115 L119 V121 P122 G125 N126 LDAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx I 1.80 BS01 PEB I 1 F14 E16 C20 A22 T25 Q26 K27 A28 G33 F34 C35 K37 F14 E16 C20 A22 T25 Q26 K27 A28 G33 F34 C35 K37 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx I 1.80 BS02 DBV J 1 Y57 N58 K60 L61 A64 K65 S66 Y57 N58 K60 L61 A64 K65 S66 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx I 1.80 BS03 PEB J 1 V13 F14 R17 F34 V13 F14 R17 F34 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx I 1.80 BS04 PEB J 2 M2 K4 D5 S6 K7 M2 K4 D5 S6 K7 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx I 1.80 BS05 PEB K 1 K44 M45 N46 A47 K44 M45 N46 A47 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx J 1.80 BS01 DBV J 1 C50 I51 D54 S57 G58 C61 I133 A136 T137 F141 S146 Q147 Q148 K149 C48 I49 D52 S55 G56 C59 I131 A134 T135 F139 S144 Q145 Q146 K147 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx J 1.80 BS02 PEB J 1 K28 N35 K36 M38 D39 S40 I142 T153 P154 G156 C158 K26 N33 K34 M36 D37 S38 I140 T151 P152 G154 C156 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx J 1.80 BS03 PEB J 3 M59 G72 V73 K78 A81 C82 R84 D85 I88 R108 L113 Y117 L120 V122 P123 G126 N127 M57 G70 V71 K76 A79 C80 R82 D83 I86 R106 L111 Y115 L118 V120 P121 G124 N125 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx J 1.80 BS04 PEB K 1 N76 R77 A80 N74 R75 A78 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx K 1.80 BS01 PEB I 1 K44 M45 A47 K44 M45 A47 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx K 1.80 BS02 PEB K 1 F14 E16 C20 K21 A22 T25 Q26 K27 A28 G33 F34 C35 K37 F14 E16 C20 K21 A22 T25 Q26 K27 A28 G33 F34 C35 K37 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx K 1.80 BS03 DBV L 1 Y57 N58 K60 L61 A64 K65 S66 Y57 N58 K60 L61 A64 K65 S66 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx K 1.80 BS04 PEB L 1 V13 F14 R17 F34 V13 F14 R17 F34 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx K 1.80 BS05 PEB L 2 M2 K4 D5 S6 M2 K4 D5 S6 AMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIKMNAAEATSVTKNYNTKLLGAKS 4lmx L 1.80 BS01 PEB I 1 N76 R77 A80 N74 R75 A78 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx L 1.80 BS02 DBV L 1 C50 I51 D54 S57 G58 C61 R129 I133 A136 T137 F141 S146 Q147 Q148 K149 C48 I49 D52 S55 G56 C59 R127 I131 A134 T135 F139 S144 Q145 Q146 K147 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx L 1.80 BS03 PEB L 1 K28 N35 K36 M38 D39 S40 I142 N144 T153 P154 G156 C158 K26 N33 K34 M36 D37 S38 I140 N142 T151 P152 G154 C156 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4lmx L 1.80 BS04 PEB L 3 M59 G72 V73 R77 K78 A81 C82 R84 D85 I88 R108 L113 Y117 L120 V122 P123 G126 N127 M57 G70 V71 R75 K76 A79 C80 R82 D83 I86 R106 L111 Y115 L118 V120 P121 G124 N125 DAFSKVITSADGKAAYVGGADLQALKKFVSEGNKRMDSVNAIVSNASCIVSDSVSGMVCENPSLIAPNGGVYTNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARTISIMKATVIGFITNNSQQKKLSTPAGDCSALASEVGGYFDKVSSALA 4m00 A 2.05 BS01 CA A 1 D365 Y367 N369 D382 D115 Y117 N119 D132 Q2FUW1 24901708 TTAVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDVKAPTVTVGNQTIEVGKTMNPIVLTTTDNGTGTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPISPIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKTTTTFKYEVTRN 4m00 A 2.05 BS02 CA A 2 D573 K575 D601 N602 D645 D323 K325 D351 N352 D395 Q2FUW1 24901708 TTAVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDVKAPTVTVGNQTIEVGKTMNPIVLTTTDNGTGTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPISPIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKTTTTFKYEVTRN 4m00 A 2.05 BS03 CA A 3 D661 T663 D690 N691 D734 N738 D411 T413 D440 N441 D484 N488 Q2FUW1 24901708 TTAVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDVKAPTVTVGNQTIEVGKTMNPIVLTTTDNGTGTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPISPIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKTTTTFKYEVTRN 4m01 A 2.10 BS01 CA A 1 D365 Y367 N369 D382 D113 Y115 N117 D130 Q2FUW1 24901708 AVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTD 4m01 B 2.10 BS01 CA B 1 D365 Y367 N369 D382 D113 Y115 N117 D130 Q2FUW1 24901708 AVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTD 4m01 C 2.10 BS01 CA C 1 D365 Y367 N369 D382 D113 Y115 N117 D130 Q2FUW1 24901708 AVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDV 4m01 D 2.10 BS01 CA D 1 D365 Y367 N369 D382 D113 Y115 N117 D130 Q2FUW1 24901708 AVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDV 4m02 A 1.59 BS01 CA A 1 D573 K575 D601 N602 D645 D79 K81 D107 N108 D151 Q2FUW1 24901708 AVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDVKAPTVTVGNQTIEVGKTMNPIVLTTTDNGTGTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTT 4m03 A 2.24 BS01 CA A 1 D203 T205 D232 N233 D276 N280 D77 T79 D106 N107 D150 N154 Q2FUW1 24901708 TVTVGNQTIEVGKTMNPIVLTTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPISPIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKTTTTFKYEVT 4m2j A 2.95 BS01 PLP A 1 G90 S91 S92 Y116 N166 D194 T222 S224 K225 R233 G89 S90 S91 Y115 N165 D193 T221 S223 K224 R232 G9MBV4 24505011 SSLRPRREDPPVLEEWYRRHLGPDIHDISSSGVHPYSFAEIRDVCRIPAADLDAVVMDDSVSQGGEGVRRAIADRYAGGDADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHSLGHYPRAAGCDVAVLPGRAVRDGEIDPDVLAGLVTPGTAAVIVNFPHNPTGVTLSPQGLRALKERTAATGAVLVWDAATAEIAHRWEVLADPGADGGDTVSYGTLSKTFGLPGLRVGWAVAPKELLTATFPLRDRTTLFLSPLVELVAERAVRHADELIGARAAEARHNLAHLTGWMAAHEELVRWTPPEGGVCALPVFRELERAAAGPQEVERFCLELLERHRTLLVPGTAFGAPHGARLGFGGPQEDFRAGLDGLSRFLRERA 4m2k A 2.00 BS01 PLP A 1 G90 S91 S92 Y116 N162 N166 D194 T222 S224 K225 R233 G89 S90 S91 Y115 N161 N165 D193 T221 S223 K224 R232 G9MBV4 24505011 SSLRPRREDPPVLEEWYRRHLGPDIHDISSSGVHPYSFAEIRDVCRIPAADLDAVVMDDSVSQGGEGVRRAIADRYAGGDADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHSLGHYPRAAGCDVAVLPGRAVRDGEIDPDVLAGLVTPGTAAVIVNFPHNPTGVTLSPQGLRALKERTAATGAVLVWDAATAEIAHRWEVLADPGADGGDTVSYGTLSKTFGLPGLRVGWAVAPKELLTATFPLRDRTTLFLSPLVELVAERAVRHADELIGARAAEARHNLAHLTGWMAAHEELVRWTPPEGGVCALPVFRELERAAAGPQEVERFCLELLERHRTLLVPGTAFGAPHGARLGFGGPQEDFRAGLDGLSRFLRERA 4m2m A 1.58 BS01 PLP A 1 G90 S91 S92 Y116 N162 N166 D194 T222 S224 K225 R233 G85 S86 S87 Y111 N157 N161 D189 T217 S219 K220 R228 G9MBV4 24505011 PRREDPPVLEEWYRRHLGPDIHDISSSGVHPYSFAEIRDVCRIPAADLDAVVMDDSVSQGGEGVRRAIADRYAGGDADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHSLGHYPRAAGCDVAVLPGRAVRDGEIDPDVLAGLVTPGTAAVIVNFPHNPTGVTLSPQGLRALKERTAATGAVLVWDAATAEIAHRWEVLADPGADGGDTVSYGTLSKTFGLPGLRVGWAVAPKELLTATFPLRDRTTLFLSPLVELVAERAVRHADELIGARAAEARHNLAHLTGWMAAHEELVRWTPPEGGVCALPVFRELERAAAGPQEVERFCLELLERHRTLLVPGTAFGAPHGARLGFGGPQEDFRAGLDGLSRFLRERAAG 4m2m A 1.58 BS02 ARG A 1 L14 E15 Y18 L22 S32 Y116 N166 K225 R358 L9 E10 Y13 L17 S27 Y111 N161 K220 R353 G9MBV4 24505011 PRREDPPVLEEWYRRHLGPDIHDISSSGVHPYSFAEIRDVCRIPAADLDAVVMDDSVSQGGEGVRRAIADRYAGGDADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHSLGHYPRAAGCDVAVLPGRAVRDGEIDPDVLAGLVTPGTAAVIVNFPHNPTGVTLSPQGLRALKERTAATGAVLVWDAATAEIAHRWEVLADPGADGGDTVSYGTLSKTFGLPGLRVGWAVAPKELLTATFPLRDRTTLFLSPLVELVAERAVRHADELIGARAAEARHNLAHLTGWMAAHEELVRWTPPEGGVCALPVFRELERAAAGPQEVERFCLELLERHRTLLVPGTAFGAPHGARLGFGGPQEDFRAGLDGLSRFLRERAAG 4m3p A 1.90 BS01 ZN A 1 C217 C299 C300 C186 C268 C269 2.1.1.5 Q93088 24895213 KKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYSGQEVNEAACDIARQVADEGDALVAGGVSQTPKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQ 4m3p A 1.90 BS02 K A 1 D26 G27 Q72 Q247 G298 C299 D17 G18 Q63 Q216 G267 C268 2.1.1.5 Q93088 24895213 KKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYSGQEVNEAACDIARQVADEGDALVAGGVSQTPKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQ 4m3p B 1.90 BS01 ZN B 1 C217 C299 C300 C187 C269 C270 2.1.1.5 Q93088 24895213 KAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYSGQEVNEAACDIARQVADEGDALVAGGVSQTPSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKF 4m3p B 1.90 BS02 K B 1 D26 G27 Q72 Q247 G298 C299 D19 G20 Q65 Q217 G268 C269 2.1.1.5 Q93088 24895213 KAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYSGQEVNEAACDIARQVADEGDALVAGGVSQTPSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKF 4m3p C 1.90 BS01 ZN C 1 C217 C299 C300 C193 C275 C276 2.1.1.5 Q93088 24895213 KKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYKISGQEVNEAACDIARQVADEGDALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWKELFEK 4m3p C 1.90 BS02 K C 1 D26 G27 G28 Q72 Q247 G298 C299 D17 G18 G19 Q63 Q223 G274 C275 2.1.1.5 Q93088 24895213 KKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYKISGQEVNEAACDIARQVADEGDALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWKELFEK 4m3p D 1.90 BS01 ZN D 1 C217 C299 C300 C191 C273 C274 2.1.1.5 Q93088 24895213 KKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYSGQEVNEAACDIARQVADEGDALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWAELMQQKEATTEQQLKELFEKQKF 4m3p D 1.90 BS02 K D 1 D26 G27 Q72 Q247 G298 C299 D17 G18 Q63 Q221 G272 C273 2.1.1.5 Q93088 24895213 KKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYSGQEVNEAACDIARQVADEGDALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAAQLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWAELMQQKEATTEQQLKELFEKQKF 4m8d A 1.90 BS01 MN A 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d A 1.90 BS02 23J A 1 L35 H73 H77 D79 H83 G196 F209 H212 L35 H73 H77 D79 H83 G196 F209 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d B 1.90 BS01 23J A 1 F63 W65 F62 W64 A0NLY7 SAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d B 1.90 BS02 MN B 1 H73 H77 D79 H83 H72 H76 D78 H82 A0NLY7 SAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d B 1.90 BS03 23J B 1 L35 L37 F41 H83 F209 H212 L34 L36 F40 H82 F208 H211 A0NLY7 SAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d B 1.90 BS04 CA B 1 N228 D230 K231 N227 D229 K230 A0NLY7 SAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d C 1.90 BS01 MN C 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d C 1.90 BS02 23J C 1 L35 H73 H77 D79 H83 G196 H212 L35 H73 H77 D79 H83 G196 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d C 1.90 BS03 CA C 1 N228 D230 K231 N228 D230 K231 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d C 1.90 BS04 23J D 1 F63 W65 F63 W65 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d D 1.90 BS01 23J C 1 F63 W65 F63 W65 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d D 1.90 BS02 MN D 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d D 1.90 BS03 23J D 1 L35 H73 H77 D79 H83 G196 H212 L35 H73 H77 D79 H83 G196 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d E 1.90 BS01 MN E 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d E 1.90 BS02 23J E 1 L35 L37 H73 H77 D79 H83 W84 G196 F209 H212 L35 L37 H73 H77 D79 H83 W84 G196 F209 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d F 1.90 BS01 23J E 1 F63 W65 F63 W65 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d F 1.90 BS02 MN F 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d F 1.90 BS03 23J F 1 L35 L37 H73 H77 D79 H83 W84 G196 H212 L35 L37 H73 H77 D79 H83 W84 G196 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d G 1.90 BS01 MN G 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d G 1.90 BS02 23J G 1 L35 L37 F41 H83 W84 F209 H212 L35 L37 F41 H83 W84 F209 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d G 1.90 BS03 23J H 1 F63 W65 F63 W65 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d H 1.90 BS01 23J G 1 F63 W65 F63 W65 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d H 1.90 BS02 MN H 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d H 1.90 BS03 23J H 1 L35 L37 H73 H77 D79 H83 W84 G196 F209 H212 L35 L37 H73 H77 D79 H83 W84 G196 F209 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPKA 4m8d I 1.90 BS01 MN I 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d I 1.90 BS02 23J I 1 L35 H73 H77 D79 H83 W84 G196 F209 H212 L35 H73 H77 D79 H83 W84 G196 F209 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d I 1.90 BS03 23J J 1 F63 W65 F63 W65 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d J 1.90 BS01 23J I 1 F63 W65 F63 W65 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d J 1.90 BS02 MN J 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d J 1.90 BS03 23J J 1 L35 H73 H77 D79 H83 W84 G196 F209 H212 L35 H73 H77 D79 H83 W84 G196 F209 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d J 1.90 BS04 CA J 1 K153 N228 K153 N228 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d K 1.90 BS01 MN K 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d K 1.90 BS02 23J K 1 L35 H73 H77 D79 H83 W84 G196 H212 L35 H73 H77 D79 H83 W84 G196 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d K 1.90 BS03 23J L 1 F63 W65 F63 W65 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d L 1.90 BS01 23J K 1 F63 W65 F63 W65 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d L 1.90 BS02 MN L 1 H73 H77 D79 H83 H73 H77 D79 H83 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4m8d L 1.90 BS03 23J L 1 L35 H73 H77 D79 H83 G196 F209 H212 L35 H73 H77 D79 H83 G196 F209 H212 A0NLY7 MSAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK 4mcp A 1.65 BS01 ZN A 1 D387 E425 H553 D332 E370 H498 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcp A 1.65 BS02 ZN A 2 H377 D387 D453 H322 D332 D398 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcp A 1.65 BS03 CA A 1 T269 Y272 E433 E436 T214 Y217 E378 E381 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcp A 1.65 BS04 28Z A 1 R210 N257 A424 E425 G427 L428 E457 R463 G518 N519 R534 R536 T538 W541 S547 G548 Y552 H553 K699 Y700 R155 N202 A369 E370 G372 L373 E402 R408 G463 N464 R479 R481 T483 W486 S492 G493 Y497 H498 K642 Y643 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcq A 2.00 BS01 ZN A 1 D387 E425 H553 D332 E370 H498 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcq A 2.00 BS02 ZN A 2 H377 D387 D453 H322 D332 D398 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcq A 2.00 BS03 CA A 1 T269 Y272 P273 E433 E436 T214 Y217 P218 E378 E381 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcq A 2.00 BS04 29C A 1 K207 R210 N257 D387 A424 E425 G427 L428 R463 R511 G518 N519 R534 R536 W541 E542 Y552 H553 N698 K699 Y700 K152 R155 N202 D332 A369 E370 G372 L373 R408 R456 G463 N464 R479 R481 W486 E487 Y497 H498 N641 K642 Y643 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcr A 1.65 BS01 ZN A 1 D387 E425 H553 D332 E370 H498 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcr A 1.65 BS02 ZN A 2 H377 D387 D453 H322 D332 D398 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcr A 1.65 BS03 CA A 1 D266 T269 Y272 E433 E436 D211 T214 Y217 E378 E381 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcr A 1.65 BS04 29D A 1 R210 N257 D387 A424 E425 G427 L428 R463 R511 S513 G518 N519 R534 R536 W541 E542 Y552 H553 K699 Y700 A701 R155 N202 D332 A369 E370 G372 L373 R408 R456 S458 G463 N464 R479 R481 W486 E487 Y497 H498 K642 Y643 A644 3.4.17.21 Q04609 24863754 HNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcs A 1.83 BS01 ZN A 1 D387 E425 H553 D333 E371 H496 3.4.17.21 Q04609 24863754 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcs A 1.83 BS02 ZN A 2 H377 D387 D453 H323 D333 D399 3.4.17.21 Q04609 24863754 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcs A 1.83 BS03 CA A 1 T269 Y272 P273 E433 E436 T215 Y218 P219 E379 E382 3.4.17.21 Q04609 24863754 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcs A 1.83 BS04 GLU A 1 R210 N257 E424 E425 G427 L428 G518 Y552 H553 K699 Y700 R156 N203 E370 E371 G373 L374 G464 Y495 H496 K640 Y641 3.4.17.21 Q04609 24863754 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mcs A 1.83 BS05 ASP A 1 D453 G518 N519 R534 Y552 H553 D399 G464 N465 R480 Y495 H496 3.4.17.21 Q04609 24863754 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4mne A 2.85 BS01 ACP A 1 L74 G75 A76 G77 N78 V82 A95 K97 M143 E144 M146 S150 Q153 K192 S194 N195 L197 D208 L12 G13 A14 G15 N16 V20 A33 K35 M81 E82 M84 S88 Q91 K130 S132 N133 L135 D146 2.7.12.2 Q02750 LKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTI 4mne A 2.85 BS02 MG A 1 K97 N195 D208 K35 N133 D146 2.7.12.2 Q02750 LKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTI 4mne A 2.85 BS03 573 A 1 N78 G79 G80 K97 I99 L115 V127 I141 M143 C207 D208 F209 G210 V211 S212 L215 I216 N16 G17 G18 K35 I37 L53 V65 I79 M81 C145 D146 F147 G148 V149 S150 L153 I154 2.7.12.2 Q02750 LKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTI 4mne D 2.85 BS01 ACP D 1 L74 G75 A76 G77 N78 G80 V82 A95 K97 M143 E144 M146 S150 Q153 K192 S194 N195 L197 D208 L9 G10 A11 G12 N13 G15 V17 A30 K32 M78 E79 M81 S85 Q88 K127 S129 N130 L132 D143 2.7.12.2 Q02750 DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLN 4mne D 2.85 BS02 MG D 1 N195 D208 N130 D143 2.7.12.2 Q02750 DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLN 4mne D 2.85 BS03 573 D 1 G77 G79 G80 K97 V127 I141 M143 C207 D208 F209 G210 V211 S212 L215 I216 M219 G12 G14 G15 K32 V62 I76 M78 C142 D143 F144 G145 V146 S147 L150 I151 M154 2.7.12.2 Q02750 DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLN 4mne E 2.85 BS01 ACP E 1 L74 G77 N78 V82 A95 K97 M143 E144 M146 S150 Q153 K192 S194 N195 L197 D208 L13 G16 N17 V21 A34 K36 M82 E83 M85 S89 Q92 K131 S133 N134 L136 D147 2.7.12.2 Q02750 ELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTI 4mne E 2.85 BS02 MG E 1 N195 D208 N134 D147 2.7.12.2 Q02750 ELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTI 4mne E 2.85 BS03 573 E 1 N78 G79 K97 L115 V127 I141 M143 D208 F209 G210 V211 S212 L215 I216 M219 N17 G18 K36 L54 V66 I80 M82 D147 F148 G149 V150 S151 L154 I155 M158 2.7.12.2 Q02750 ELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTI 4mne H 2.85 BS01 ACP H 1 L74 G75 A76 G77 N78 G80 V82 A95 K97 M143 E144 M146 S150 Q153 K192 S194 N195 L197 D208 L9 G10 A11 G12 N13 G15 V17 A30 K32 M78 E79 M81 S85 Q88 K127 S129 N130 L132 D143 2.7.12.2 Q02750 DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIG 4mne H 2.85 BS02 MG H 1 N195 D208 N130 D143 2.7.12.2 Q02750 DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIG 4mne H 2.85 BS03 573 H 1 N78 G79 G80 K97 L118 V127 I141 M143 C207 D208 F209 G210 V211 S212 L215 I216 M219 N13 G14 G15 K32 L53 V62 I76 M78 C142 D143 F144 G145 V146 S147 L150 I151 M154 2.7.12.2 Q02750 DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIG 4mne H 2.85 BS04 573 H 2 H87 L92 M94 H119 Y130 H22 L27 M29 H54 Y65 2.7.12.2 Q02750 DDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIG 4mnf A 2.80 BS01 29L A 1 V471 A481 E501 L514 T529 W531 C532 N580 F583 D594 V23 A33 E53 L66 T81 W83 C84 N132 F135 D146 2.7.11.1 P15056 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATESILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARS 4mnf B 2.80 BS01 29L B 1 I463 V471 A481 K483 E501 I527 T529 W531 C532 N580 F583 I15 V23 A33 K35 E53 I79 T81 W83 C84 N132 F135 2.7.11.1 P15056 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATESILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARS 4ms7 A 1.67 BS01 ZN A 1 H341 H343 D354 H94 H96 D107 3.4.19.- Q9P371 24787148 FKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4ms7 A 1.67 BS02 ZN A 2 H356 C397 H404 H406 H109 C150 H157 H159 3.4.19.- Q9P371 24787148 FKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4ms7 B 1.67 BS01 ZN B 1 H356 C397 H404 H406 H110 C151 H158 H160 3.4.19.- Q9P371 24787148 TFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRV 4ms7 B 1.67 BS02 ZN B 2 H341 H343 D354 H95 H97 D108 3.4.19.- Q9P371 24787148 TFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRV 4msd A 1.90 BS01 ZN A 1 H341 H343 D354 H93 H95 D106 3.4.19.- Q9P371 24787148 KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGITDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msd A 1.90 BS02 ZN A 2 H356 C397 H404 H406 H108 C149 H156 H158 3.4.19.- Q9P371 24787148 KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGITDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msd B 1.90 BS01 ZN B 1 H341 H343 D354 H93 H95 D106 3.4.19.- Q9P371 24787148 KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGITDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msd B 1.90 BS02 ZN B 2 H356 C397 H404 H406 H108 C149 H156 H158 3.4.19.- Q9P371 24787148 KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGITDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msj A 1.80 BS01 ZN A 1 H341 H343 D354 H98 H100 D111 3.4.19.- Q9P371 24787148 MAGTFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msj A 1.80 BS02 ZN A 2 H356 C397 H404 H406 H113 C154 H161 H163 3.4.19.- Q9P371 24787148 MAGTFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msj B 1.80 BS01 ZN B 1 H341 H343 D354 H95 H97 D108 3.4.19.- Q9P371 24787148 TFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRV 4msj B 1.80 BS02 ZN B 2 H356 C397 H404 H406 H110 C151 H158 H160 3.4.19.- Q9P371 24787148 TFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRV 4msj C 1.80 BS01 ZN C 1 H341 H343 D354 H95 H97 D108 3.4.19.- Q9P371 24787148 TFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msj C 1.80 BS02 ZN C 2 H356 C397 H404 H406 H110 C151 H158 H160 3.4.19.- Q9P371 24787148 TFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msm A 1.74 BS01 ZN A 1 H341 H343 D354 H93 H95 D106 3.4.19.- Q9P371 24787148 KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLATCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRV 4msm A 1.74 BS02 ZN A 2 H356 C397 H404 H406 H108 C149 H156 H158 3.4.19.- Q9P371 24787148 KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLATCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRV 4msm C 1.74 BS01 ZN C 1 H341 H343 D354 H94 H96 D107 3.4.19.- Q9P371 24787148 FKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLATCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msm C 1.74 BS02 ZN C 2 H356 C397 H404 H406 H109 C150 H157 H159 3.4.19.- Q9P371 24787148 FKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLATCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msq A 1.95 BS01 ZN A 1 H356 C397 H404 H406 H108 C149 H156 H158 3.4.19.- Q9P371 24787148 KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msq A 1.95 BS02 ZN A 2 H341 H343 D354 H93 H95 D106 3.4.19.- Q9P371 24787148 KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msq C 1.95 BS01 ZN C 1 H356 C397 H404 H406 H109 C150 H157 H159 3.4.19.- Q9P371 24787148 FKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4msq C 1.95 BS02 ZN C 2 H341 H343 D354 H94 H96 D107 3.4.19.- Q9P371 24787148 FKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4mu5 A 1.80 BS01 HEM A 1 L41 F42 Y44 H64 K67 V68 V71 L92 H96 V101 F106 V109 L39 F40 Y42 H62 K65 V66 V69 L90 H94 V99 F104 V107 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAWSRGWDG 4mux A 1.70 BS01 SF4 A 1 C12 G14 V15 C96 L98 T167 C197 Y198 A268 C12 G14 V15 C96 L98 T167 C197 Y198 A268 1.17.1.2 C9QSC3 24813236 MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELR 4mux A 1.70 BS02 2E4 A 1 V15 V40 H41 A73 H74 V99 H124 E126 T167 T168 S225 S226 N227 S269 V15 V40 H41 A73 H74 V99 H124 E126 T167 T168 S225 S226 N227 S269 1.17.1.2 C9QSC3 24813236 MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELR 4mux B 1.70 BS01 SF4 B 1 C12 G14 C96 L98 T167 C197 Y198 A268 C12 G14 C96 L98 T167 C197 Y198 A268 1.17.1.2 C9QSC3 24813236 MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRV 4mux B 1.70 BS02 2E4 B 1 V15 V40 H41 A73 H74 V99 H124 E126 T167 T168 N224 S225 S226 N227 S269 V15 V40 H41 A73 H74 V99 H124 E126 T167 T168 N224 S225 S226 N227 S269 1.17.1.2 C9QSC3 24813236 MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRV 4mv5 A 1.90 BS01 F3S A 1 C12 G14 C96 L98 T167 C197 Y198 A268 C12 G14 C96 L98 T167 C197 Y198 A268 1.17.1.2 C9QSC3 24813236 MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELR 4mv5 A 1.90 BS02 2E7 A 1 V15 V40 H41 A73 H74 V99 H124 E126 T167 T168 N224 S225 S226 N227 S269 V15 V40 H41 A73 H74 V99 H124 E126 T167 T168 N224 S225 S226 N227 S269 1.17.1.2 C9QSC3 24813236 MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELR 4mv5 B 1.90 BS01 F3S B 1 C12 G14 V15 C96 L98 T167 C197 Y198 A268 C12 G14 V15 C96 L98 T167 C197 Y198 A268 1.17.1.2 C9QSC3 24813236 MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRV 4mv5 B 1.90 BS02 2E7 B 1 V15 V40 H41 A73 H74 V99 H124 E126 T167 T168 N224 S225 S226 N227 S269 V15 V40 H41 A73 H74 V99 H124 E126 T167 T168 N224 S225 S226 N227 S269 1.17.1.2 C9QSC3 24813236 MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRV 4n16 A 1.54 BS01 ZN A 1 H94 H96 H119 H92 H94 H117 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4ne0 A 2.17 BS01 FE A 1 H154 E156 H303 H147 E149 H296 G9MBV2 24505011 STPSYSLTPAEASAVAELTLELAAAYGSFGDPVLLRDLPRLAARLPEGVQDFLREFKLADRHGHTVIRGHDFDQRRIGPTPDHWRGRVRPGPEFPEELLLMLYSALLGEPFGWATQQDGHLVHDIFPIRSHENDQLGMGSKQLLTWHTEAAFHPYRSDYLILGALRNPDHVPTTVGELDLSSLSAEDIDVLFEPRYHIAPDESHLPKNNTIATEEEAARFATIQRMIDERPLGPLLYGSRLDPYMRLDPYFTSVPQDDTDARRAYDALFKVVDSGMREVVADQGDVLFIDNHRAVHGRLPFQARYDGTDRWLKRVCVTSDLRRSREMRATSATRLLG 4ne0 B 2.17 BS01 FE B 1 H154 E156 H303 R321 H136 E138 H263 R281 G9MBV2 24505011 TPSYSLTPAEASAVAELTLELAAAYGSFGDPVLLRDLPRLAARLPEGVQDFLREFKLADRHGHTVIRGHDFDQRRIGPTPDHWRGRVRPGPEFPEELLLMLYSALLGEPFGWATQQDGHLVHDIFPIRSHELLTWHTEAAFHPYRSDYLILGALRNPDHVPTTVGELDLSSLSAEDIDVLFEPRYHIAPDESMIDERPLGPLLYGSRLDPYMRLDPYFTSVPQDDTDARRAYDALFKVVDSGMREVVADQGDVLFIDNHRAVHGRLPFQARYDGTDRWLKRVCVTSDLRRSREMRATSATRLLG 4ne0 C 2.17 BS01 FE C 1 H154 E156 H303 R321 H146 E148 H281 R299 G9MBV2 24505011 TPSYSLTPAEASAVAELTLELAAAYGSFGDPVLLRDLPRLAARLPEGVQDFLREFKLADRHGHTVIRGHDFDQRRIGPTPDHWRGRVRPGPEFPEELLLMLYSALLGEPFGWATQQDGHLVHDIFPIRSHENDQLGMGSKQLLTWHTEAAFHPYRSDYLILGALRNPDHVPTTVGELDLSSLSAEDIDVLFEPRYHIAPDESHLPATIQRMIDERPLGPLLYGSRLDPYMRLDPYFTSVPQDDTDARRAYDALFKVVDSGMREVVADQGDVLFIDNHRAVHGRLPFQARYDGTDRWLKRVCVTSDLRRSREMRATSATRLLG 4ne0 C 2.17 BS02 ZZU C 1 Q123 L143 G144 H154 E156 D208 S210 D255 F258 R321 Q115 L135 G136 H146 E148 D200 S202 D233 F236 R299 G9MBV2 24505011 TPSYSLTPAEASAVAELTLELAAAYGSFGDPVLLRDLPRLAARLPEGVQDFLREFKLADRHGHTVIRGHDFDQRRIGPTPDHWRGRVRPGPEFPEELLLMLYSALLGEPFGWATQQDGHLVHDIFPIRSHENDQLGMGSKQLLTWHTEAAFHPYRSDYLILGALRNPDHVPTTVGELDLSSLSAEDIDVLFEPRYHIAPDESHLPATIQRMIDERPLGPLLYGSRLDPYMRLDPYFTSVPQDDTDARRAYDALFKVVDSGMREVVADQGDVLFIDNHRAVHGRLPFQARYDGTDRWLKRVCVTSDLRRSREMRATSATRLLG 4ne0 D 2.17 BS01 FE D 1 H154 E156 H303 R321 H146 E148 H275 R293 G9MBV2 24505011 TPSYSLTPAEASAVAELTLELAAAYGSFGDPVLLRDLPRLAARLPEGVQDFLREFKLADRHGHTVIRGHDFDQRRIGPTPDHWRGRVRPGPEFPEELLLMLYSALLGEPFGWATQQDGHLVHDIFPIRSHENDQLGMGSKQLLTWHTEAAFHPYRSDYLILGALRNPDHVPTTVGELDLSSLSAEDIDVLFEPRYHIAPDESHRMIDERPLGPLLYGSRLDPYMRLDPYFTSVPQDDTDARRAYDALFKVVDSGMREVVADQGDVLFIDNHRAVHGRLPFQARYDGTDRWLKRVCVTSDLRRSREMRATSATRLLG 4ne0 D 2.17 BS02 ZZU D 1 Q123 Q142 L143 H154 E156 D208 S210 D255 F258 R321 Q115 Q134 L135 H146 E148 D200 S202 D227 F230 R293 G9MBV2 24505011 TPSYSLTPAEASAVAELTLELAAAYGSFGDPVLLRDLPRLAARLPEGVQDFLREFKLADRHGHTVIRGHDFDQRRIGPTPDHWRGRVRPGPEFPEELLLMLYSALLGEPFGWATQQDGHLVHDIFPIRSHENDQLGMGSKQLLTWHTEAAFHPYRSDYLILGALRNPDHVPTTVGELDLSSLSAEDIDVLFEPRYHIAPDESHRMIDERPLGPLLYGSRLDPYMRLDPYFTSVPQDDTDARRAYDALFKVVDSGMREVVADQGDVLFIDNHRAVHGRLPFQARYDGTDRWLKRVCVTSDLRRSREMRATSATRLLG 4ngm A 1.84 BS01 ZN A 1 H377 D387 D453 H323 D333 D399 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngm A 1.84 BS02 ZN A 2 D387 E425 H553 D333 E371 H499 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngm A 1.84 BS03 CA A 1 D266 T269 Y272 P273 E433 E436 D212 T215 Y218 P219 E379 E382 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngm A 1.84 BS04 JB7 A 1 G206 K207 R210 N257 E424 E425 G427 L428 G518 N519 R534 R536 F546 S547 G548 Y552 H553 N698 K699 Y700 A701 G152 K153 R156 N203 E370 E371 G373 L374 G464 N465 R480 R482 F492 S493 G494 Y498 H499 N644 K645 Y646 A647 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngn A 1.64 BS01 ZN A 1 H377 D387 D453 H323 D333 D399 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngn A 1.64 BS02 ZN A 2 D387 E425 H553 D333 E371 H499 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngn A 1.64 BS03 CA A 1 T269 Y272 E433 E436 T215 Y218 E379 E382 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngn A 1.64 BS04 J96 A 1 R210 N257 E424 E425 G427 L428 G518 N519 R534 R536 Y552 H553 K699 Y700 R156 N203 E370 E371 G373 L374 G464 N465 R480 R482 Y498 H499 K645 Y646 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngp A 1.63 BS01 J31 A 1 R210 N257 E424 E425 G427 L428 E457 R463 G518 N519 R534 R536 W541 N544 F546 Y552 H553 K699 Y700 A701 R156 N203 E370 E371 G373 L374 E403 R409 G464 N465 R480 R482 W487 N490 F492 Y498 H499 K644 Y645 A646 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngp A 1.63 BS02 ZN A 1 H377 D387 D453 H323 D333 D399 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngp A 1.63 BS03 ZN A 2 D387 E425 H553 D333 E371 H499 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngp A 1.63 BS04 CA A 1 T269 Y272 E433 E436 T215 Y218 E379 E382 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngq A 2.08 BS01 ZN A 1 H377 D387 D453 H323 D333 D399 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngq A 2.08 BS02 ZN A 2 D387 E425 H553 D333 E371 H497 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngq A 2.08 BS03 CA A 1 D266 T269 Y272 P273 E433 E436 D212 T215 Y218 P219 E379 E382 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngq A 2.08 BS04 J37 A 1 R210 N257 E424 E425 G427 L428 E457 R463 D465 G518 N519 R534 R536 Y552 H553 K699 Y700 R156 N203 E370 E371 G373 L374 E403 R409 D411 G464 N465 R480 R482 Y496 H497 K643 Y644 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngr A 1.90 BS01 J21 A 1 K207 R210 Y234 N257 E424 E425 G427 L428 R463 G518 N519 R534 R536 G548 Y552 H553 N698 K699 Y700 A701 K153 R156 Y180 N203 E370 E371 G373 L374 R409 G464 N465 R480 R482 G487 Y491 H492 N637 K638 Y639 A640 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngr A 1.90 BS02 ZN A 1 H377 D387 D453 H323 D333 D399 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngr A 1.90 BS03 ZN A 2 D387 E425 H553 D333 E371 H492 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngr A 1.90 BS04 CA A 1 D266 T269 Y272 P273 E433 E436 D212 T215 Y218 P219 E379 E382 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngs A 1.68 BS01 J34 A 1 R210 N257 E424 E425 G427 L428 E457 R463 G518 N519 R534 R536 T538 W541 N544 F546 G548 Y552 H553 N698 K699 Y700 R156 N203 E370 E371 G373 L374 E403 R409 G464 N465 R480 R482 T484 W487 N490 F492 G494 Y498 H499 N644 K645 Y646 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngs A 1.68 BS02 ZN A 1 H377 D387 D453 H323 D333 D399 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngs A 1.68 BS03 ZN A 2 D387 E425 H553 D333 E371 H499 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngs A 1.68 BS04 CA A 1 T269 Y272 P273 E433 E436 T215 Y218 P219 E379 E382 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngt A 2.31 BS01 ZN A 1 H377 D387 E425 D453 H323 D333 E371 D399 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngt A 2.31 BS02 ZN A 2 D387 E425 H553 D333 E371 H495 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngt A 2.31 BS03 CA A 1 D266 T269 Y272 E433 E436 D212 T215 Y218 E379 E382 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4ngt A 2.31 BS04 J42 A 1 R210 N257 E424 E425 G427 E457 R463 G518 N519 R534 R536 T538 K539 W541 Y552 H553 K699 Y700 A701 R156 N203 E370 E371 G373 E403 R409 G464 N465 R480 R482 T484 K485 W487 Y494 H495 K641 Y642 A643 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 4nzi A 2.10 BS01 HEM A 1 L31 L38 L41 F42 Y44 H64 K67 V68 V71 I72 Y88 L92 K95 H96 V101 F106 V109 W140 L29 L36 L39 F40 Y42 H62 K65 V66 V69 I70 Y86 L90 K93 H94 V99 F104 V107 W138 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGWDG 4o0z A 2.05 BS01 2RM A 1 Y188 H191 F193 R196 D219 S241 V242 A244 S275 I309 R311 I351 Y172 H175 F177 R180 D203 S225 V226 A228 S259 I293 R295 I335 2.4.2.12 P43490 24797455 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELE 4o0z B 2.05 BS01 2RM B 1 Y188 H191 F193 R196 D219 S241 V242 A244 S275 R311 I351 Y171 H174 F176 R179 D202 S224 V225 A227 S258 R294 I334 2.4.2.12 P43490 24797455 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIEL 4o10 A 1.55 BS01 2QF A 1 Y188 H191 F193 R196 D219 S241 V242 A244 P273 S275 I309 R311 I351 Y172 H175 F177 R180 D203 S225 V226 A228 P257 S259 I293 R295 I335 2.4.2.12 P43490 24797455 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELE 4o10 A 1.55 BS02 2QF B 1 D16 Y18 D9 Y11 2.4.2.12 P43490 24797455 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELE 4o10 B 1.55 BS01 2QF B 1 Y188 H191 F193 R196 D219 S241 V242 A244 P273 S275 I309 R311 I351 Y171 H174 F176 R179 D202 S224 V225 A227 P256 S258 I292 R294 I334 2.4.2.12 P43490 24797455 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIEL 4o12 A 2.50 BS01 2QG A 1 Y188 H191 F193 R196 D219 V242 A244 S275 I309 R311 I351 Y172 H175 F177 R180 D203 V226 A228 S259 I293 R295 I335 2.4.2.12 P43490 24797455 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEA 4o12 B 2.50 BS01 2QG A 1 D16 Y18 D9 Y11 2.4.2.12 P43490 24797455 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEA 4o12 B 2.50 BS02 2QG B 1 K189 H191 F193 R196 D219 V242 A244 S275 I309 R311 R349 V350 I351 E376 N377 I378 A379 K172 H174 F176 R179 D202 V225 A227 S258 I292 R294 R332 V333 I334 E359 N360 I361 A362 2.4.2.12 P43490 24797455 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEA 4o1t A 1.60 BS01 HEM A 1 L38 L41 F42 Y44 H64 K67 V68 V71 Y88 L92 H96 V101 W106 V109 L36 L39 F40 Y42 H62 K65 V66 V69 Y86 L90 H94 V99 W104 V107 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSWSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 4o2g A 2.70 BS01 HEM A 1 L41 F42 Y44 H64 K67 V71 L92 H96 V101 S105 F106 V109 Y137 M144 L39 F40 Y42 H62 K65 V69 L90 H94 V99 S103 F104 V107 Y135 M142 Q9ER97 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGW 4o35 A 1.80 BS01 HEM A 1 L41 F42 Y44 H64 K67 V71 L92 H96 L103 S105 W106 V109 Y137 V140 M144 L41 F42 Y44 H64 K67 V71 L92 H96 L103 S105 W106 V109 Y137 V140 M144 Q9ER97 MERPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSWSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWD 4o4d A 2.10 BS01 I3P A 1 K115 K118 R119 R152 Y153 H234 K85 K88 R89 R122 Y123 H204 2.7.4.21 N9UNA8 PDGQYLLKPCLSHRERDFYLHIKDDKEWTGTGIIPKFYGVELHEFGFGELEFIRMENLMYKYKRPFVLDLKIGTQTWDPETASSKMKKRLVVDSTSTTTSLGVRFSGMERNIGEEKPILYSRYLCTHEVNTRDSLKEYIKLFFNDGKKYRKELVPYFISQLDKMIEVMKKREYKMFSSSVLFVYDSTTTLEDKKYNCKMIDFAHNWILSEEECTVEDGFLFGLNNLKSILEDIENEFKSL 4o4d A 2.10 BS02 ATP A 1 L36 K38 M85 E86 N87 L88 M89 D99 L211 D231 L6 K8 M55 E56 N57 L58 M59 D69 L181 D201 2.7.4.21 N9UNA8 PDGQYLLKPCLSHRERDFYLHIKDDKEWTGTGIIPKFYGVELHEFGFGELEFIRMENLMYKYKRPFVLDLKIGTQTWDPETASSKMKKRLVVDSTSTTTSLGVRFSGMERNIGEEKPILYSRYLCTHEVNTRDSLKEYIKLFFNDGKKYRKELVPYFISQLDKMIEVMKKREYKMFSSSVLFVYDSTTTLEDKKYNCKMIDFAHNWILSEEECTVEDGFLFGLNNLKSILEDIENEFKSL 4o4e A 1.90 BS01 5MY A 1 G23 Q27 K101 K115 K118 R119 R152 Y153 G1 Q5 K77 K91 K94 R95 R128 Y129 2.7.4.21 N9UNA8 GSFTQQPDGQYLLKPCLSHRERDFYLHIKDDKEWTGTGIIPKFYGVELHEFGFGELEFIRMENLMYKYKRPFVLDLKIGTQTWDPETASSKMKKRLVVDSTSTTTSLGVRFSGMERNIGEEKPILYSRYLCTHEVNTRDSLKEYIKLFFNDGKKYRKELVPYFISQLDKMIEVMKKREYKMFSSSVLFVYDSTTTLEDKKYNCKMIDFAHNWILSEEECTVEDGFLFGLNNLKSILEDIENEFKSL 4o4e A 1.90 BS02 ATP A 1 G23 S24 F25 Q27 L36 K38 M85 E86 N87 L88 D99 I230 D231 A233 G1 S2 F3 Q5 L12 K14 M61 E62 N63 L64 D75 I206 D207 A209 2.7.4.21 N9UNA8 GSFTQQPDGQYLLKPCLSHRERDFYLHIKDDKEWTGTGIIPKFYGVELHEFGFGELEFIRMENLMYKYKRPFVLDLKIGTQTWDPETASSKMKKRLVVDSTSTTTSLGVRFSGMERNIGEEKPILYSRYLCTHEVNTRDSLKEYIKLFFNDGKKYRKELVPYFISQLDKMIEVMKKREYKMFSSSVLFVYDSTTTLEDKKYNCKMIDFAHNWILSEEECTVEDGFLFGLNNLKSILEDIENEFKSL 4o4f A 1.70 BS01 IHP A 1 G23 Q27 K101 K115 K118 R119 R152 Y153 G1 Q5 K77 K91 K94 R95 R128 Y129 2.7.4.21 N9UNA8 GSFTQQPDGQYLLKPCLSHRERDFYLHIKDDKEWTGTGIIPKFYGVELHEFGFGELEFIRMENLMYKYKRPFVLDLKIGTQTWDPETASSKMKKRLVVDSTSTTTSLGVRFSGMERNIGEEKPILYSRYLCTHEVNTRDSLKEYIKLFFNDGKKYRKELVPYFISQLDKMIEVMKKREYKMFSSSVLFVYDSTTTLEDKKYNCKMIDFAHNWILSEEECTVEDGFLFGLNNLKSILEDIENEFKSL 4o4f A 1.70 BS02 ATP A 1 G23 S24 F25 Q27 L36 K38 M85 E86 N87 L88 D99 I230 D231 G1 S2 F3 Q5 L12 K14 M61 E62 N63 L64 D75 I206 D207 2.7.4.21 N9UNA8 GSFTQQPDGQYLLKPCLSHRERDFYLHIKDDKEWTGTGIIPKFYGVELHEFGFGELEFIRMENLMYKYKRPFVLDLKIGTQTWDPETASSKMKKRLVVDSTSTTTSLGVRFSGMERNIGEEKPILYSRYLCTHEVNTRDSLKEYIKLFFNDGKKYRKELVPYFISQLDKMIEVMKKREYKMFSSSVLFVYDSTTTLEDKKYNCKMIDFAHNWILSEEECTVEDGFLFGLNNLKSILEDIENEFKSL 4o4f A 1.70 BS03 PO4 A 1 R201 D247 G248 F249 L250 R177 D223 G224 F225 L226 2.7.4.21 N9UNA8 GSFTQQPDGQYLLKPCLSHRERDFYLHIKDDKEWTGTGIIPKFYGVELHEFGFGELEFIRMENLMYKYKRPFVLDLKIGTQTWDPETASSKMKKRLVVDSTSTTTSLGVRFSGMERNIGEEKPILYSRYLCTHEVNTRDSLKEYIKLFFNDGKKYRKELVPYFISQLDKMIEVMKKREYKMFSSSVLFVYDSTTTLEDKKYNCKMIDFAHNWILSEEECTVEDGFLFGLNNLKSILEDIENEFKSL 4o8c B 2.00 BS01 MG B 1 D10 D12 D206 D211 D10 D12 D206 D211 3.1.3.1 Q8L1N9 MRKYNGYLIDLDGTMYRGTERIDAASGFIKELNRLHIPYLFVTNNSTRTPEQVADKLVSLDIPATPEQIFTSSMATANYVYDLDQNAMIYFIGEEGLYKALKEKGFSFADENADVVIVGLDREVTYEKLAVACLAVRNGAKLISTNGDLALPTERGFMPGNGAFTALISYSTQVKATFVGKPEPIIMEQALKVLGTNKNETIMVGDNYDTDILAGIRAGLDTLLVHTGVTTVEKLKEYKQQPTYSMKSLDDWKFL 4ooe A 1.83 BS01 FOM A 1 D151 S152 E153 A176 S177 H200 Y203 M205 S213 N218 K219 E222 M267 D140 S141 E142 A165 S166 H189 Y192 M194 S202 N207 K208 E211 M256 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVS 4ooe A 1.83 BS02 MN A 1 K128 D151 S152 E153 E222 K117 D140 S141 E142 E211 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVS 4ooe A 1.83 BS03 NDP A 1 G19 T21 G22 S23 I24 A46 G47 G48 A49 H50 A69 A103 L104 V105 L108 A126 N127 K128 E129 D151 M205 G206 N209 M267 G8 T10 G11 S12 I13 A35 G36 G37 A38 H39 A58 A92 L93 V94 L97 A115 N116 K117 E118 D140 M194 G195 N198 M256 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVS 4ooe B 1.83 BS01 FOM B 1 D151 S152 E153 A176 S177 H200 Y203 M205 S213 N218 K219 E222 M267 D140 S141 E142 A165 S166 H189 Y192 M194 S202 N207 K208 E211 M256 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4ooe B 1.83 BS02 MN B 1 K128 D151 E153 E222 K117 D140 E142 E211 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4ooe B 1.83 BS03 NDP B 1 G19 T21 G22 S23 I24 A46 G47 G48 A49 H50 A69 A103 L104 V105 A126 N127 K128 E129 D151 M205 G206 N209 M267 G8 T10 G11 S12 I13 A35 G36 G37 A38 H39 A58 A92 L93 V94 A115 N116 K117 E118 D140 M194 G195 N198 M256 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4ooe C 1.83 BS01 FOM C 1 D151 S152 E153 A176 S177 H200 Y203 S213 N218 K219 E222 M267 D140 S141 E142 A165 S166 H189 Y192 S202 N207 K208 E211 M256 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSG 4ooe C 1.83 BS02 MN C 1 K128 D151 S152 E153 E222 K117 D140 S141 E142 E211 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSG 4ooe C 1.83 BS03 NDP C 1 G19 T21 G22 S23 I24 A46 G47 G48 A49 H50 A69 A103 L104 V105 L108 A126 N127 K128 E129 D151 M205 G206 P207 N209 M267 G8 T10 G11 S12 I13 A35 G36 G37 A38 H39 A58 A92 L93 V94 L97 A115 N116 K117 E118 D140 M194 G195 P196 N198 M256 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSG 4ooe D 1.83 BS01 FOM D 1 D151 S152 E153 A176 S177 H200 Y203 M205 S213 N218 K219 E222 M267 D140 S141 E142 A165 S166 H189 Y192 M194 S202 N207 K208 E211 M256 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4ooe D 1.83 BS02 MN D 1 K128 D151 S152 E153 E222 K117 D140 S141 E142 E211 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4ooe D 1.83 BS03 NDP D 1 G19 T21 G22 S23 I24 A46 G47 G48 A49 H50 A69 A103 L104 V105 A126 N127 K128 E129 D151 M205 G206 N209 M267 G8 T10 G11 S12 I13 A35 G36 G37 A38 H39 A58 A92 L93 V94 A115 N116 K117 E118 D140 M194 G195 N198 M256 1.1.1.267 I6YAH0 24825256 RLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTYSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM 4oof A 2.30 BS01 NDP A 1 G19 T21 G22 S23 I24 A46 G47 G48 A49 H50 A69 A103 L104 V105 L108 A126 N127 K128 E129 D151 M205 G206 P207 N209 M267 G9 T11 G12 S13 I14 A36 G37 G38 A39 H40 A59 A93 L94 V95 L98 A116 N117 K118 E119 D141 M195 G196 P197 N199 M257 1.1.1.267 I6YAH0 24825256 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTFSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSG 4oof A 2.30 BS02 MN A 1 K128 D151 S152 E153 E222 K118 D141 S142 E143 E212 1.1.1.267 I6YAH0 24825256 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTFSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSG 4oof A 2.30 BS03 FOM A 1 D151 S152 E153 A176 S177 H200 F203 M205 S213 N218 K219 E222 M267 D141 S142 E143 A166 S167 H190 F193 M195 S203 N208 K209 E212 M257 1.1.1.267 I6YAH0 24825256 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTFSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSG 4oof B 2.30 BS01 NDP B 1 G19 T21 G22 S23 I24 A46 G47 G48 A49 H50 A69 A103 L104 V105 L108 A126 N127 K128 E129 D151 M205 G206 N209 M267 G9 T11 G12 S13 I14 A36 G37 G38 A39 H40 A59 A93 L94 V95 L98 A116 N117 K118 E119 D141 M195 G196 N199 M257 1.1.1.267 I6YAH0 24825256 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTFSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSG 4oof B 2.30 BS02 MN B 1 K128 D151 S152 E153 E222 K118 D141 S142 E143 E212 1.1.1.267 I6YAH0 24825256 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTFSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSG 4oof B 2.30 BS03 FOM B 1 D151 S152 E153 A176 S177 H200 F203 M205 S213 N218 K219 E222 M267 D141 S142 E143 A166 S167 H190 F193 M195 S203 N208 K209 E212 M257 1.1.1.267 I6YAH0 24825256 GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTFSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSG 4ooo A 2.15 BS01 RU0 A 1 W62 W63 L75 D101 W62 W63 L75 D101 3.2.1.17 P00698 24796316 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4ooo A 2.15 BS02 RU0 A 2 A122 W123 A122 W123 3.2.1.17 P00698 24796316 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4oyg A 3.50 BS01 ASP A 1 R276 S277 S278 M311 T314 Y317 G354 V355 P356 G357 A358 G359 D394 T398 N401 R271 S272 S273 M306 T309 Y312 G349 V350 P351 G352 A353 G354 D389 T393 N396 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg A 3.50 BS02 NA A 1 T308 M311 S349 I350 G351 T352 A353 T303 M306 S344 I345 G346 T347 A348 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg A 3.50 BS03 NA A 2 S278 G306 A307 T308 N310 M311 N401 D405 S273 G301 A302 T303 N305 M306 N396 D400 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg B 3.50 BS01 ASP B 1 R276 S277 S278 M311 T314 Y317 T352 G354 V355 P356 G357 A358 G359 D394 T398 N401 R271 S272 S273 M306 T309 Y312 T347 G349 V350 P351 G352 A353 G354 D389 T393 N396 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg B 3.50 BS02 NA B 1 T308 M311 S349 I350 G351 T352 A353 T303 M306 S344 I345 G346 T347 A348 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg B 3.50 BS03 NA B 2 S278 G306 A307 N310 M311 N401 V402 D405 S273 G301 A302 N305 M306 N396 V397 D400 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg C 3.50 BS01 ASP C 1 R276 S277 S278 M311 T314 Y317 T352 G354 V355 P356 G357 A358 G359 D394 T398 N401 R271 S272 S273 M306 T309 Y312 T347 G349 V350 P351 G352 A353 G354 D389 T393 N396 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg C 3.50 BS02 NA C 1 T308 M311 S349 I350 G351 T352 A353 T303 M306 S344 I345 G346 T347 A348 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg C 3.50 BS03 NA C 2 S278 G306 A307 N310 M311 N401 V402 D405 S273 G301 A302 N305 M306 N396 V397 D400 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg D 3.50 BS01 ASP D 1 R276 S277 S278 M311 T314 Y317 T352 G354 V355 P356 G357 A358 G359 D394 T398 N401 R271 S272 S273 M306 T309 Y312 T347 G349 V350 P351 G352 A353 G354 D389 T393 N396 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg D 3.50 BS02 NA D 1 T308 M311 S349 I350 G351 T352 A353 T303 M306 S344 I345 G346 T347 A348 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg D 3.50 BS03 NA D 2 S278 G306 A307 N310 M311 N401 V402 D405 S273 G301 A302 N305 M306 N396 V397 D400 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg E 3.50 BS01 ASP E 1 R276 S277 S278 M311 T314 Y317 G354 V355 P356 G357 A358 G359 D394 T398 N401 R271 S272 S273 M306 T309 Y312 G349 V350 P351 G352 A353 G354 D389 T393 N396 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg E 3.50 BS02 NA E 1 T308 M311 S349 I350 G351 T352 A353 T303 M306 S344 I345 G346 T347 A348 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg E 3.50 BS03 NA E 2 S278 G306 A307 N310 M311 N401 V402 D405 S273 G301 A302 N305 M306 N396 V397 D400 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg F 3.50 BS01 ASP F 1 R276 S277 S278 M311 T314 Y317 T352 G354 V355 P356 G357 A358 G359 D394 T398 N401 R271 S272 S273 M306 T309 Y312 T347 G349 V350 P351 G352 A353 G354 D389 T393 N396 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg F 3.50 BS02 NA F 1 T308 M311 S349 I350 G351 T352 A353 T303 M306 S344 I345 G346 T347 A348 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4oyg F 3.50 BS03 NA F 2 S278 G306 A307 N310 M311 N401 V402 D405 S273 G301 A302 N305 M306 N396 V397 D400 O59010 24842876 KYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGATMVNVTGDLTGTAIVAKTE 4p3y A 2.15 BS01 GDP A 1 D22 H23 G24 K25 T26 T27 N136 K137 D139 M140 S174 A175 L176 D14 H15 G16 K17 T18 T19 N128 K129 D131 M132 S166 A167 L168 C6EGC5 24860094 TKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG 4p7g A 2.58 BS01 PO4 A 1 K89 A110 Y111 C112 G113 Y114 S115 D184 K45 A66 Y67 C68 G69 Y70 S71 D140 2.1.1.6 P22734 GDTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQG 4p7g B 2.58 BS01 PO4 B 1 K89 Y111 C112 G113 Y114 S115 D184 K45 Y67 C68 G69 Y70 S71 D140 2.1.1.6 P22734 GDTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 4p7g C 2.58 BS01 PO4 C 1 K89 Y111 C112 G113 Y114 S115 D184 K45 Y67 C68 G69 Y70 S71 D140 2.1.1.6 P22734 GDTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 4p7g D 2.58 BS01 PO4 D 1 K89 A110 Y111 C112 G113 Y114 S115 D184 K45 A66 Y67 C68 G69 Y70 S71 D140 2.1.1.6 P22734 GDTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 4p7j A 1.45 BS01 SO4 A 1 A110 Y111 C112 G113 Y114 S115 D184 A66 Y67 C68 G69 Y70 S71 D140 2.1.1.6 P22734 GDTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGPSSP 4p7k A 1.22 BS01 SFG A 1 K89 G109 A110 Y111 Y114 S115 E133 M134 N135 Y138 G160 A161 S162 Q163 D184 H185 W186 R189 K45 G65 A66 Y67 Y70 S71 E89 M90 N91 Y94 G116 A117 S118 Q119 D140 H141 W142 R145 2.1.1.6 P22734 GDTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGPSSPDK 4p8r A 2.20 BS01 NAD A 1 N8 G9 G11 R12 I13 N33 D34 R78 S96 T97 G98 L99 T120 C150 A181 N314 Y318 N8 G9 G11 R12 I13 N33 D34 R78 S96 T97 G98 L99 T120 C150 A181 N314 Y318 1.2.1.12 Q38AR9 MVIRVGINGFGRIGRVVFRAAQRRNDIEIVGINDLLDADYMAYMLKYDSTHGRFEGAVEVQGGALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITGPSKDDTPMFVMGVNHTTYKGEAIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATTATQKTVDGPSQKDWRGGRGAAQNIIPSSTGAAKAVGKIIPSLNGKLTGMAFRVPTPNVSVVDLTVRLERPATYKQICDAIKAASEGELKGILGYVDEEIVSSDINGIPLTSVFDARAGISLNDNFVKLVSWYDNETGYSNKVLDLIAHITK 4p8r A 2.20 BS02 MG A 1 A21 R24 I27 E28 A21 R24 I27 E28 1.2.1.12 Q38AR9 MVIRVGINGFGRIGRVVFRAAQRRNDIEIVGINDLLDADYMAYMLKYDSTHGRFEGAVEVQGGALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITGPSKDDTPMFVMGVNHTTYKGEAIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATTATQKTVDGPSQKDWRGGRGAAQNIIPSSTGAAKAVGKIIPSLNGKLTGMAFRVPTPNVSVVDLTVRLERPATYKQICDAIKAASEGELKGILGYVDEEIVSSDINGIPLTSVFDARAGISLNDNFVKLVSWYDNETGYSNKVLDLIAHITK 4p8r B 2.20 BS01 NAD B 1 N8 G9 G11 R12 I13 N33 D34 R78 S96 T97 G98 L99 T120 C150 A181 N314 Y318 N8 G9 G11 R12 I13 N33 D34 R78 S96 T97 G98 L99 T120 C150 A181 N314 Y318 1.2.1.12 Q38AR9 MVIRVGINGFGRIGRVVFRAAQRRNDIEIVGINDLLDADYMAYMLKYDSTHGRFEGAVEVQGGALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITGPSKDDTPMFVMGVNHTTYKGEAIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATTATQKTVDGPSQKDWRGGRGAAQNIIPSSTGAAKAVGKIIPSLNGKLTGMAFRVPTPNVSVVDLTVRLERPATYKQICDAIKAASEGELKGILGYVDEEIVSSDINGIPLTSVFDARAGISLNDNFVKLVSWYDNETGYSNKVLDLIAHITK 4p8r B 2.20 BS02 MG B 1 A21 R24 I27 A21 R24 I27 1.2.1.12 Q38AR9 MVIRVGINGFGRIGRVVFRAAQRRNDIEIVGINDLLDADYMAYMLKYDSTHGRFEGAVEVQGGALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITGPSKDDTPMFVMGVNHTTYKGEAIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATTATQKTVDGPSQKDWRGGRGAAQNIIPSSTGAAKAVGKIIPSLNGKLTGMAFRVPTPNVSVVDLTVRLERPATYKQICDAIKAASEGELKGILGYVDEEIVSSDINGIPLTSVFDARAGISLNDNFVKLVSWYDNETGYSNKVLDLIAHITK 4p8r C 2.20 BS01 NAD C 1 N8 G9 F10 G11 R12 I13 N33 D34 R78 S96 T97 G98 L99 T120 C150 A181 N314 Y318 N7 G8 F9 G10 R11 I12 N32 D33 R77 S95 T96 G97 L98 T119 C149 A180 N313 Y317 1.2.1.12 Q38AR9 VIRVGINGFGRIGRVVFRAAQRRNDIEIVGINDLLDADYMAYMLKYDSTHGRFEGAVEVQGGALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITGPSKDDTPMFVMGVNHTTYKGEAIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATTATQKTVDGPSQKDWRGGRGAAQNIIPSSTGAAKAVGKIIPSLNGKLTGMAFRVPTPNVSVVDLTVRLERPATYKQICDAIKAASEGELKGILGYVDEEIVSSDINGIPLTSVFDARAGISLNDNFVKLVSWYDNETGYSNKVLDLIAHITK 4p8r D 2.20 BS01 NAD D 1 N8 G9 G11 R12 I13 N33 D34 R78 S96 T97 G98 L99 T120 C150 A181 N314 Y318 N8 G9 G11 R12 I13 N33 D34 R78 S96 T97 G98 L99 T120 C150 A181 N314 Y318 1.2.1.12 Q38AR9 MVIRVGINGFGRIGRVVFRAAQRRNDIEIVGINDLLDADYMAYMLKYDSTHGRFEGAVEVQGGALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITGPSKDDTPMFVMGVNHTTYKGEAIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATTATQKTVDGPSQKDWRGGRGAAQNIIPSSTGAAKAVGKIIPSLNGKLTGMAFRVPTPNVSVVDLTVRLERPATYKQICDAIKAASEGELKGILGYVDEEIVSSDINGIPLTSVFDARAGISLNDNFVKLVSWYDNETGYSNKVLDLIAHITK 4p8r D 2.20 BS02 MG D 1 A21 R24 I27 A21 R24 I27 1.2.1.12 Q38AR9 MVIRVGINGFGRIGRVVFRAAQRRNDIEIVGINDLLDADYMAYMLKYDSTHGRFEGAVEVQGGALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITGPSKDDTPMFVMGVNHTTYKGEAIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVHATTATQKTVDGPSQKDWRGGRGAAQNIIPSSTGAAKAVGKIIPSLNGKLTGMAFRVPTPNVSVVDLTVRLERPATYKQICDAIKAASEGELKGILGYVDEEIVSSDINGIPLTSVFDARAGISLNDNFVKLVSWYDNETGYSNKVLDLIAHITK 4p99 A 1.80 BS01 CA A 1 D312 E314 D399 D311 E313 D398 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS02 CA A 2 D225 T308 D224 T307 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS03 CA A 3 T222 D224 V226 E231 T221 D223 V225 E230 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS04 CA A 4 T326 D328 V330 E335 T325 D327 V329 E334 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS05 CA A 5 D388 A390 D387 A389 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS06 CA A 6 D329 T412 D328 T411 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS07 CA A 7 T14 D16 V18 E23 T13 D15 V17 E22 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS08 CA A 8 D17 T100 D16 T99 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS09 CA A 9 D76 A78 D75 A77 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS10 CA A 10 D104 E106 A107 D191 D103 E105 A106 D190 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS11 CA A 11 D121 T204 D120 T203 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS12 CA A 12 T118 D120 V122 E127 T117 D119 V121 E126 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS13 CA A 13 D180 A182 D179 A181 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS14 CA A 14 D208 E210 D295 D207 E209 D294 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS15 CA A 15 E2 A3 D87 E1 A2 D86 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS16 CA A 16 E152 T157 E151 T156 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 A 1.80 BS17 CA A 17 D284 A286 F287 D283 A285 F286 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS01 CA B 1 D284 A286 D283 A285 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS02 CA B 2 D208 E210 D295 D207 E209 D294 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS03 CA B 3 D17 T100 D16 T99 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS04 CA B 4 T14 D16 V18 E23 T13 D15 V17 E22 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS05 CA B 5 D104 E106 D191 D103 E105 D190 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS06 CA B 6 D121 T204 D120 T203 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS07 CA B 7 T118 D120 V122 E127 T117 D119 V121 E126 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS08 CA B 8 D180 A182 D179 A181 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS09 CA B 9 D225 T308 D224 T307 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS10 CA B 10 T222 D224 V226 E231 T221 D223 V225 E230 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS11 CA B 11 D312 E314 D399 D311 E313 D398 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS12 CA B 12 D329 T412 D328 T411 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS13 CA B 13 T326 D328 V330 E335 T325 D327 V329 E334 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS14 CA B 14 D388 A390 D387 A389 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS15 CA B 15 D76 A78 F79 D75 A77 F78 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 B 1.80 BS16 CA B 16 E2 A3 D87 E1 A2 D86 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS01 CA C 1 D312 E314 A315 D399 D311 E313 A314 D398 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS02 CA C 2 D180 A182 D179 A181 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS03 CA C 3 E2 A3 D87 E1 A2 D86 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS04 CA C 4 D17 T100 D16 T99 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS05 CA C 5 T14 D16 V18 E23 T13 D15 V17 E22 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS06 CA C 6 D104 E106 A107 D191 D103 E105 A106 D190 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS07 CA C 7 T118 D120 V122 E127 T117 D119 V121 E126 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS08 CA C 8 D121 T204 D120 T203 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS09 CA C 9 D208 E210 D295 D207 E209 D294 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS10 CA C 10 D225 T308 D224 T307 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS11 CA C 11 T222 D224 V226 E231 T221 D223 V225 E230 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS12 CA C 12 D76 A78 F79 D75 A77 F78 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS13 CA C 13 A60 N61 A59 N60 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS14 CA C 14 A164 N165 A163 N164 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS15 CA C 15 D284 A286 D283 A285 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS16 CA C 16 D329 T412 D328 T411 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS17 CA C 17 T326 D328 V330 E335 T325 D327 V329 E334 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 C 1.80 BS18 CA C 18 D388 A390 F391 D387 A389 F390 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS01 CA D 1 D17 T100 D16 T99 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS02 CA D 2 T14 D16 V18 E23 T13 D15 V17 E22 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS03 CA D 3 D76 A78 D75 A77 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS04 CA D 4 D104 E106 D191 D103 E105 D190 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS05 CA D 5 D121 T204 D120 T203 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS06 CA D 6 D180 A182 D179 A181 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS07 CA D 7 T118 D120 V122 E127 T117 D119 V121 E126 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS08 CA D 8 D208 E210 D295 D207 E209 D294 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS09 CA D 9 D225 T308 D224 T307 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS10 CA D 10 T222 D224 V226 E231 T221 D223 V225 E230 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS11 CA D 11 D284 A286 D283 A285 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS12 CA D 12 D312 E314 D399 D311 E313 D398 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS13 CA D 13 D329 T412 D328 T411 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS14 CA D 14 T326 D328 V330 E335 T325 D327 V329 E334 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS15 CA D 15 D388 A390 D387 A389 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS16 CA D 16 E2 A3 D87 E1 A2 D86 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p99 D 1.80 BS17 CA D 17 S71 A74 A75 S70 A73 A74 24892750 EATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDTEATAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 4p9s A 2.32 BS01 FAD A 1 I48 G49 G51 C52 V53 L72 E73 K74 A79 G80 S81 T82 H84 A85 A86 G87 L88 P211 V212 A240 A241 G242 W244 H263 Y265 G363 P364 I365 F390 Y392 G393 I394 I395 I11 G12 G14 C15 V16 L35 E36 K37 A42 G43 S44 T45 H47 A48 A49 G50 L51 P174 V175 A203 A204 G205 W207 H226 Y228 G326 P327 I328 F353 Y355 G356 I357 I358 1.5.8.4 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKD 4p9s B 2.32 BS01 FAD B 1 I48 G49 G51 C52 V53 L72 E73 K74 G80 S81 T82 H84 A85 A86 G87 L88 P211 V212 A240 A241 G242 W244 H263 Y265 G363 P364 I365 F390 Y392 G393 I394 I395 I11 G12 G14 C15 V16 L35 E36 K37 G43 S44 T45 H47 A48 A49 G50 L51 P174 V175 A203 A204 G205 W207 H226 Y228 G326 P327 I328 F353 Y355 G356 I357 I358 1.5.8.4 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKD 4p9v A 1.64 BS01 III B 1 R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121 R14 R33 S35 S37 S43 Q53 H54 F55 K56 L67 W68 P62993 24856058 EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ 4p9z A 1.80 BS01 III B 1 R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121 R14 R33 S35 S37 S43 Q53 H54 F55 K56 L67 W68 P62993 24856058 EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQ 4paa A 2.26 BS01 FAD A 1 I48 G49 G51 C52 V53 L72 E73 K74 G80 S81 T82 H84 A85 A86 G87 L88 V212 A241 G242 W244 H263 Y265 G363 P364 I365 F390 Y392 G393 I394 I395 I11 G12 G14 C15 V16 L35 E36 K37 G43 S44 T45 H47 A48 A49 G50 L51 V175 A204 G205 W207 H226 Y228 G326 P327 I328 F353 Y355 G356 I357 I358 1.5.8.4 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKD 4paa A 2.26 BS02 THG A 1 F530 I560 E573 T575 I587 F649 L650 Y669 E676 Y678 F717 Y737 F738 T843 F493 I523 E536 T538 I550 F612 L613 Y632 E639 Y641 F680 Y700 F701 T806 1.5.8.4 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKD 4paa B 2.26 BS01 FAD B 1 I48 G49 G51 C52 V53 L72 E73 K74 G80 S81 T82 H84 A85 A86 G87 L88 P211 V212 A240 A241 G242 W244 H263 Y265 G363 P364 I365 F390 Y392 G393 I394 I395 I11 G12 G14 C15 V16 L35 E36 K37 G43 S44 T45 H47 A48 A49 G50 L51 P174 V175 A203 A204 G205 W207 H226 Y228 G326 P327 I328 F353 Y355 G356 I357 I358 1.5.8.4 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKD 4paa B 2.26 BS02 THG B 1 F530 I560 E573 T575 I587 F649 L650 Y669 E676 Y678 F717 Y737 F493 I523 E536 T538 I550 F612 L613 Y632 E639 Y641 F680 Y700 1.5.8.4 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKD 4pab A 1.85 BS01 FAD A 1 I48 G49 G50 G51 C52 V53 L72 E73 K74 G80 S81 T82 H84 A85 A86 G87 L88 P211 V212 A240 A241 G242 W244 H263 Y265 G363 P364 I365 F390 Y392 G393 I394 I395 I11 G12 G13 G14 C15 V16 L35 E36 K37 G43 S44 T45 H47 A48 A49 G50 L51 P174 V175 A203 A204 G205 W207 H226 Y228 G326 P327 I328 F353 Y355 G356 I357 I358 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKSAAL 4pab A 1.85 BS02 THG A 1 F530 I560 E573 T575 I587 F649 L650 Y669 E676 Y678 F717 Y737 F493 I523 E536 T538 I550 F612 L613 Y632 E639 Y641 F680 Y700 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKSAAL 4pab B 1.85 BS01 FAD B 1 I48 G49 G50 G51 C52 V53 L72 E73 K74 G80 S81 T82 H84 A85 A86 G87 L88 P211 V212 A240 A241 G242 W244 H263 Y265 G363 P364 I365 F390 Y392 G393 I394 I395 I11 G12 G13 G14 C15 V16 L35 E36 K37 G43 S44 T45 H47 A48 A49 G50 L51 P174 V175 A203 A204 G205 W207 H226 Y228 G326 P327 I328 F353 Y355 G356 I357 I358 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKSAALE 4pab B 1.85 BS02 THG B 1 I560 E573 T575 I587 F649 L650 Y669 E676 Y678 F717 Y737 I523 E536 T538 I550 F612 L613 Y632 E639 Y641 F680 Y700 Q5RKL4 24858690 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKSAALE 4pca A 1.50 BS01 MN A 1 A38 D136 K139 D162 N163 A41 D139 K142 D165 N166 S6G476 HHHMRNVSLSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pca A 1.50 BS02 SAH A 1 Q39 L40 G64 T65 C66 F69 S70 E88 K89 N93 G115 E116 A117 D136 A137 N138 Y145 Q42 L43 G67 T68 C69 F72 S73 E91 K92 N96 G118 E119 A120 D139 A140 N141 Y148 S6G476 HHHMRNVSLSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pca B 1.50 BS01 MN B 1 A38 D136 K139 D162 N163 A39 D137 K140 D163 N164 S6G476 HMRNVSLSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pca B 1.50 BS02 SAH B 1 L35 Q39 L40 G64 T65 C66 F69 S70 E88 K89 N93 G115 A117 D136 N138 Y145 L36 Q40 L41 G65 T66 C67 F70 S71 E89 K90 N94 G116 A118 D137 N139 Y146 S6G476 HMRNVSLSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pca C 1.50 BS01 MN C 1 A38 D136 K139 D162 N163 A39 D137 K140 D163 N164 S6G476 HMRNVSLSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pca C 1.50 BS02 SAH C 1 Q39 L40 G64 T65 C66 F69 S70 E88 K89 N93 G115 E116 A117 D136 N138 Y145 Q40 L41 G65 T66 C67 F70 S71 E89 K90 N94 G116 E117 A118 D137 N139 Y146 S6G476 HMRNVSLSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pca D 1.50 BS01 MN D 1 A38 D136 K139 D162 N163 A41 D139 K142 D165 N166 S6G476 HHHMRNVSLSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pca D 1.50 BS02 SAH D 1 Q39 L40 G64 T65 C66 F69 S70 E88 K89 N93 G115 E116 A117 D136 N138 Y145 Q42 L43 G67 T68 C69 F72 S73 E91 K92 N96 G118 E119 A120 D139 N141 Y148 S6G476 HHHMRNVSLSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pcl A 1.85 BS01 SAM A 1 A38 Q39 L40 G64 T65 C66 F69 S70 E88 K89 D90 N93 G115 E116 A117 D136 N138 Y145 A33 Q34 L35 G59 T60 C61 F64 S65 E83 K84 D85 N88 G110 E111 A112 D131 N133 Y140 S6G476 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pcl A 1.85 BS02 MN A 1 D136 K139 D162 N163 D131 K134 D157 N158 S6G476 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pcl B 1.85 BS01 SAM B 1 A38 Q39 L40 G64 T65 C66 F69 S70 E88 K89 N93 G115 E116 A117 D136 N138 A33 Q34 L35 G59 T60 C61 F64 S65 E83 K84 N88 G110 E111 A112 D131 N133 S6G476 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pcl B 1.85 BS02 MN B 1 A38 D136 D162 N163 A33 D131 D157 N158 S6G476 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4pgp A 2.25 BS01 IAC A 1 P41 T45 F46 P47 Y100 R173 M194 T211 S212 D214 Y236 F238 P10 T14 F15 P16 Y69 R142 M163 T180 S181 D183 Y205 F207 Q315G1 PVTLNYANFPPASTFPCIQMEQWAHEVRTRTRGKVDVLTYPGGTLLGARNMLRGVMSGQADIGCISLAYHPGVFPVMSVFELPLGFTSAEAASSVLWELYSGLRPAELERVKVLTMFTSAPSHFMTVTPVRSLRDLQGMEIRGAGTLSAILEKLGATPVSMPMPEVPEAVQKGIIKGLFTSLDVMKDMNFAEMTGHVTRADQAVYPFAVIMNREAWERLSPDVQQVLDGLAAEHAAWTGRYLDAHVQDSMRWAEEKHGVQVHTLPEEDIAAMRRSVQPLFDAWAQRAADKGADPDAVMRTVDALKAQY 4pgp B 2.25 BS01 IAC B 1 F40 P41 T45 F46 P47 Y100 R173 M194 T211 S212 D214 V215 Y236 F238 F9 P10 T14 F15 P16 Y69 R142 M163 T180 S181 D183 V184 Y205 F207 Q315G1 PVTLNYANFPPASTFPCIQMEQWAHEVRTRTRGKVDVLTYPGGTLLGARNMLRGVMSGQADIGCISLAYHPGVFPVMSVFELPLGFTSAEAASSVLWELYSGLRPAELERVKVLTMFTSAPSHFMTVTPVRSLRDLQGMEIRGAGTLSAILEKLGATPVSMPMPEVPEAVQKGIIKGLFTSLDVMKDMNFAEMTGHVTRADQAVYPFAVIMNREAWERLSPDVQQVLDGLAAEHAAWTGRYLDAHVQDSMRWAEEKHGVQVHTLPEEDIAAMRRSVQPLFDAWAQRAADKGADPDAVMRTVDALKAQYG 4pgp C 2.25 BS01 IAC C 1 F40 P41 T45 F46 P47 Y100 R173 M194 T211 S212 D214 Y236 F238 F9 P10 T14 F15 P16 Y69 R142 M163 T180 S181 D183 Y205 F207 Q315G1 PVTLNYANFPPASTFPCIQMEQWAHEVRTRTRGKVDVLTYPGGTLLGARNMLRGVMSGQADIGCISLAYHPGVFPVMSVFELPLGFTSAEAASSVLWELYSGLRPAELERVKVLTMFTSAPSHFMTVTPVRSLRDLQGMEIRGAGTLSAILEKLGATPVSMPMPEVPEAVQKGIIKGLFTSLDVMKDMNFAEMTGHVTRADQAVYPFAVIMNREAWERLSPDVQQVLDGLAAEHAAWTGRYLDAHVQDSMRWAEEKHGVQVHTLPEEDIAAMRRSVQPLFDAWAQRAADKGADPDAVMRTVDALKAQYGG 4pgp D 2.25 BS01 IAC D 1 F40 P41 T45 F46 P47 Y100 R173 M194 T211 S212 D214 V215 Y236 F238 F9 P10 T14 F15 P16 Y69 R142 M163 T180 S181 D183 V184 Y205 F207 Q315G1 PVTLNYANFPPASTFPCIQMEQWAHEVRTRTRGKVDVLTYPGGTLLGARNMLRGVMSGQADIGCISLAYHPGVFPVMSVFELPLGFTSAEAASSVLWELYSGLRPAELERVKVLTMFTSAPSHFMTVTPVRSLRDLQGMEIRGAGTLSAILEKLGATPVSMPMPEVPEAVQKGIIKGLFTSLDVMKDMNFAEMTGHVTRADQAVYPFAVIMNREAWERLSPDVQQVLDGLAAEHAAWTGRYLDAHVQDSMRWAEEKHGVQVHTLPEEDIAAMRRSVQPLFDAWAQRAADKGADPDAVMRTVDALKAQYGG 4pl0 A 2.70 BS01 ANP A 1 Y354 I360 P379 S380 G381 S382 G383 K384 S385 T386 Q426 E506 H537 Y346 I352 P371 S372 G373 S374 G375 K376 S377 T378 Q418 E498 H529 Q9X2W0 LFNYIYSLMDVRGKFLFFSMLFITSLSSIIISISPLILAKITDLLSGSLSNFSYEYLVLLACLYMFCVISNKASVFLFMILQSSLRINMQKKMSLKYLRELYNENITNLSKNNAGYTTQSLNQASNDIYILVRNVSQNILSPVIQLISTIVVVLSTKDWFSAGVFFLYILVFVIFNTRLTGSLASLRKHSMDITLNSYSLLSDTVDNMIAAKKNNALRLISERYEDALTQENNAQKKYWLLSSKVLLLNSLLAVILFGSVFIYNILGVLNGVVSIGHFIMITSYIILLSTPVENIGALLSEIRQSMSSLAGFIQRHAENKATSPSIPFLNMERKLNLSIRELSFSYSDDKKILNSVSLDLFTGKMYSLTGPSGSGKSTLVKIISGYYKNYFGDIYLNDISLRNISDEDLNDAIYYLTQDDYIFMDTLRFNLRLANYDASENEIFKVLKLANLSVVNNEPVSLDTHLINRGNNYSGGQKQRISLARLFLRKPAIIIIDEATSALDYINESEILSSIRTHFPDALIINISHRINLLECSDCVYVLNEGNIVASGHFRDLMVSNEYISGLASVT 4pl0 A 2.70 BS02 MG A 1 S385 Q426 D505 S377 Q418 D497 Q9X2W0 LFNYIYSLMDVRGKFLFFSMLFITSLSSIIISISPLILAKITDLLSGSLSNFSYEYLVLLACLYMFCVISNKASVFLFMILQSSLRINMQKKMSLKYLRELYNENITNLSKNNAGYTTQSLNQASNDIYILVRNVSQNILSPVIQLISTIVVVLSTKDWFSAGVFFLYILVFVIFNTRLTGSLASLRKHSMDITLNSYSLLSDTVDNMIAAKKNNALRLISERYEDALTQENNAQKKYWLLSSKVLLLNSLLAVILFGSVFIYNILGVLNGVVSIGHFIMITSYIILLSTPVENIGALLSEIRQSMSSLAGFIQRHAENKATSPSIPFLNMERKLNLSIRELSFSYSDDKKILNSVSLDLFTGKMYSLTGPSGSGKSTLVKIISGYYKNYFGDIYLNDISLRNISDEDLNDAIYYLTQDDYIFMDTLRFNLRLANYDASENEIFKVLKLANLSVVNNEPVSLDTHLINRGNNYSGGQKQRISLARLFLRKPAIIIIDEATSALDYINESEILSSIRTHFPDALIINISHRINLLECSDCVYVLNEGNIVASGHFRDLMVSNEYISGLASVT 4pl0 A 2.70 BS03 ANP B 1 V463 N464 N479 N480 S482 G483 G484 Q485 V455 N456 N471 N472 S474 G475 G476 Q477 Q9X2W0 LFNYIYSLMDVRGKFLFFSMLFITSLSSIIISISPLILAKITDLLSGSLSNFSYEYLVLLACLYMFCVISNKASVFLFMILQSSLRINMQKKMSLKYLRELYNENITNLSKNNAGYTTQSLNQASNDIYILVRNVSQNILSPVIQLISTIVVVLSTKDWFSAGVFFLYILVFVIFNTRLTGSLASLRKHSMDITLNSYSLLSDTVDNMIAAKKNNALRLISERYEDALTQENNAQKKYWLLSSKVLLLNSLLAVILFGSVFIYNILGVLNGVVSIGHFIMITSYIILLSTPVENIGALLSEIRQSMSSLAGFIQRHAENKATSPSIPFLNMERKLNLSIRELSFSYSDDKKILNSVSLDLFTGKMYSLTGPSGSGKSTLVKIISGYYKNYFGDIYLNDISLRNISDEDLNDAIYYLTQDDYIFMDTLRFNLRLANYDASENEIFKVLKLANLSVVNNEPVSLDTHLINRGNNYSGGQKQRISLARLFLRKPAIIIIDEATSALDYINESEILSSIRTHFPDALIINISHRINLLECSDCVYVLNEGNIVASGHFRDLMVSNEYISGLASVT 4pl0 B 2.70 BS01 ANP A 1 V463 N464 N479 N480 S482 G483 G484 Q485 A510 V460 N461 N476 N477 S479 G480 G481 Q482 A507 Q9X2W0 KQKNSLFNYIYSLMDVRGKFLFFSMLFITSLSSIIISISPLILAKITDLLSGSLSNFSYEYLVLLACLYMFCVISNKASVFLFMILQSSLRINMQKKMSLKYLRELYNENITNLSKNNAGYTTQSLNQASNDIYILVRNVSQNILSPVIQLISTIVVVLSTKDWFSAGVFFLYILVFVIFNTRLTGSLASLRKHSMDITLNSYSLLSDTVDNMIAAKKNNALRLISERYEDALTQENNAQKKYWLLSSKVLLLNSLLAVILFGSVFIYNILGVLNGVVSIGHFIMITSYIILLSTPVENIGALLSEIRQSMSSLAGFIQRHAENKATSPSIPFLNMERKLNLSIRELSFSYSDDKKILNSVSLDLFTGKMYSLTGPSGSGKSTLVKIISGYYKNYFGDIYLNDISLRNISDEDLNDAIYYLTQDDYIFMDTLRFNLRLANYDASENEIFKVLKLANLSVVNNEPVSLDTHLINRGNNYSGGQKQRISLARLFLRKPAIIIIDEATSALDYINESEILSSIRTHFPDALIINISHRINLLECSDCVYVLNEGNIVASGHFRDLMVSNEYISGLASVT 4pl0 B 2.70 BS02 ANP B 1 Y354 I360 S380 G381 S382 G383 K384 S385 T386 Q426 E506 H537 Y351 I357 S377 G378 S379 G380 K381 S382 T383 Q423 E503 H534 Q9X2W0 KQKNSLFNYIYSLMDVRGKFLFFSMLFITSLSSIIISISPLILAKITDLLSGSLSNFSYEYLVLLACLYMFCVISNKASVFLFMILQSSLRINMQKKMSLKYLRELYNENITNLSKNNAGYTTQSLNQASNDIYILVRNVSQNILSPVIQLISTIVVVLSTKDWFSAGVFFLYILVFVIFNTRLTGSLASLRKHSMDITLNSYSLLSDTVDNMIAAKKNNALRLISERYEDALTQENNAQKKYWLLSSKVLLLNSLLAVILFGSVFIYNILGVLNGVVSIGHFIMITSYIILLSTPVENIGALLSEIRQSMSSLAGFIQRHAENKATSPSIPFLNMERKLNLSIRELSFSYSDDKKILNSVSLDLFTGKMYSLTGPSGSGKSTLVKIISGYYKNYFGDIYLNDISLRNISDEDLNDAIYYLTQDDYIFMDTLRFNLRLANYDASENEIFKVLKLANLSVVNNEPVSLDTHLINRGNNYSGGQKQRISLARLFLRKPAIIIIDEATSALDYINESEILSSIRTHFPDALIINISHRINLLECSDCVYVLNEGNIVASGHFRDLMVSNEYISGLASVT 4pl0 B 2.70 BS03 MG B 1 S385 Q426 S382 Q423 Q9X2W0 KQKNSLFNYIYSLMDVRGKFLFFSMLFITSLSSIIISISPLILAKITDLLSGSLSNFSYEYLVLLACLYMFCVISNKASVFLFMILQSSLRINMQKKMSLKYLRELYNENITNLSKNNAGYTTQSLNQASNDIYILVRNVSQNILSPVIQLISTIVVVLSTKDWFSAGVFFLYILVFVIFNTRLTGSLASLRKHSMDITLNSYSLLSDTVDNMIAAKKNNALRLISERYEDALTQENNAQKKYWLLSSKVLLLNSLLAVILFGSVFIYNILGVLNGVVSIGHFIMITSYIILLSTPVENIGALLSEIRQSMSSLAGFIQRHAENKATSPSIPFLNMERKLNLSIRELSFSYSDDKKILNSVSLDLFTGKMYSLTGPSGSGKSTLVKIISGYYKNYFGDIYLNDISLRNISDEDLNDAIYYLTQDDYIFMDTLRFNLRLANYDASENEIFKVLKLANLSVVNNEPVSLDTHLINRGNNYSGGQKQRISLARLFLRKPAIIIIDEATSALDYINESEILSSIRTHFPDALIINISHRINLLECSDCVYVLNEGNIVASGHFRDLMVSNEYISGLASVT 4plb B 2.69 BS01 NUC E 1 E435 G436 D437 S438 R458 G459 K460 D508 D512 R1033 K1043 V1045 H1046 H1079 H1081 G1082 S1085 R1092 I1175 R1272 E19 G20 D21 S22 R42 G43 K44 D92 D96 R214 K224 V226 H227 H260 H262 G263 S266 R273 I356 R453 5.99.1.3 P20831 24900889 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYANERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLG 4plb B 2.69 BS02 NUC F 1 K460 I461 L462 N463 K466 R471 H515 V626 R629 F1022 R1122 F1123 I1175 A1176 V1177 G1178 M1179 R1238 K44 I45 L46 N47 K50 R55 H99 V176 R179 F203 R303 F304 I356 A357 V358 G359 M360 R419 5.99.1.3 P20831 24900889 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYANERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLG 4plb B 2.69 BS03 31N F 1 A1068 G1072 D1083 M1121 A249 G253 D264 M302 5.99.1.3 P20831 24900889 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYANERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLG 4plb B 2.69 BS04 MN B 1 E435 D508 E19 D92 5.99.1.3 P20831 24900889 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYANERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLG 4plb D 2.69 BS01 NUC E 1 K460 I461 L462 N463 K466 R471 H515 L519 V626 R629 F1022 R1122 F1123 I1175 A1176 G1178 M1179 R1238 S1330 K44 I45 L46 N47 K50 R55 H99 L103 V176 R179 F202 R302 F303 I355 A356 G358 M359 R418 S510 5.99.1.3 P20831 24900889 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYNERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQL 4plb D 2.69 BS02 NUC F 1 E435 G436 D437 S438 R458 G459 K460 D508 D512 R1033 K1043 V1045 H1046 H1079 H1081 G1082 S1085 R1092 S1173 I1175 R1272 E19 G20 D21 S22 R42 G43 K44 D92 D96 R213 K223 V225 H226 H259 H261 G262 S265 R272 S353 I355 R452 5.99.1.3 P20831 24900889 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYNERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQL 4plb D 2.69 BS03 31N F 1 A1068 M1075 D1083 A248 M255 D263 5.99.1.3 P20831 24900889 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYNERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQL 4plb D 2.69 BS04 MN D 1 E435 D508 D510 E19 D92 D94 5.99.1.3 P20831 24900889 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYNERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQL 4plm A 2.80 BS01 CA A 1 F109 D112 T120 S279 F70 D73 T81 S238 Q90922 24876346 PDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCGKPPSRYCVVTEKGEEQVRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNKPSRAAITKQNEQEAICTDSHTDVRPLSGGLIAFSTLDGRPTAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDEDDSELARDSYFYAVSDLQVGGRCKCNGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKECDCHPVGAAGQTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIP 4pln A 3.20 BS01 CA A 1 F109 D112 T120 S279 F70 D73 T81 S240 Q90922 24876346 PDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCGKPPSRYCVVTEKGEEQVRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNKPSRAAITKQNEQEAICTDSHTDVRPLSGGLIAFSTLDGRPTAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKECDCHPVGAAGQTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKI 4pln B 3.20 BS01 CA B 1 F109 D112 T120 S279 F70 D73 T81 S240 Q90922 24876346 PDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCGKPPSRYCVVTEKGEEQVRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNKPSRAAITKQNEQEAICTDSHTDVRPLSGGLIAFSTLDGRPTAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKECDCHPVGAAGQTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKI 4plo A 2.90 BS01 CA A 1 F109 D112 T120 S279 F70 D73 T81 S235 Q90922 24876346 PDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCGKPPSRYCVVTEKGEEQVRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNKPSRAAITKQNEQEAICTDSHTDVRPLSGGLIAFSTLDGRPTAHDFDNSPVLQDWVTATDIKVTFSRLHTFDDSELARDSYFYAVSDLQVGGRCKCNGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKECDCHPVGAAGQTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKI 4pmm A 2.00 BS01 31V A 1 L516 A542 K544 E560 L563 L564 L567 F589 E590 Y591 M592 F646 H648 L657 G667 D668 F669 L16 A39 K41 E54 L57 L58 L61 F83 E84 Y85 M86 F140 H142 L151 G161 D162 F163 2.7.10.1 P04629 24914455 CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLDKMLVAVKALKESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAHHHH 4pmp A 1.80 BS01 31W A 1 V524 A542 K544 L564 L567 V573 F589 E590 Y591 M592 L657 I666 G667 D668 F669 V24 A38 K40 L56 L59 V65 F81 E82 Y83 M84 L149 I158 G159 D160 F161 2.7.10.1 P04629 24914455 CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLKMLVAVKALKSARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRIYSTDYYRVGTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAHHHH 4pms A 2.80 BS01 31X A 1 L516 V524 A542 K544 L564 I572 V573 F589 D596 L657 D668 F669 G670 M671 L16 V24 A39 K41 L58 I66 V67 F83 D90 L151 D162 F163 G164 M165 2.7.10.1 P04629 24914455 CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLDKMLVAVKALKESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAHHHH 4pmt A 2.10 BS01 31Y A 1 L516 G517 V524 A542 F589 E590 Y591 M592 R599 R654 L657 G667 D668 R673 L16 G17 V24 A38 F76 E77 Y78 M79 R86 R141 L144 G154 D155 R158 2.7.10.1 P04629 24914455 CVHHIKRRDIVLKWELGEGAFGKVFLAECHNLDKMLVAVKALDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFSRDIYSTDYYRVTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAHHHH 4poh A 2.30 BS01 III B 1 F277 V280 K284 L294 V298 L301 R302 T449 F450 E453 A457 F33 V36 K40 L50 V54 L57 R58 T205 F206 E209 A213 P19793 24801499 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4poh A 2.30 BS02 2VR A 1 I268 A271 A272 Q275 W305 F313 R316 L326 A327 I345 C432 L436 F439 I24 A27 A28 Q31 W61 F69 R72 L82 A83 I101 C188 L192 F195 P19793 24801499 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4poj A 2.00 BS01 III B 1 F277 V280 K284 L294 Q297 V298 L301 R302 T449 F450 E453 A457 F33 V36 K40 L50 Q53 V54 L57 R58 T205 F206 E209 A213 P19793 24801499 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4poj A 2.00 BS02 2VP A 1 I268 A271 A272 Q275 F313 R316 L326 A327 I345 F346 V349 L436 F439 I24 A27 A28 Q31 F69 R72 L82 A83 I101 F102 V105 L192 F195 P19793 24801499 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4pp3 A 2.00 BS01 III B 1 F277 V280 K284 L294 Q297 V298 L301 R302 T449 F450 E453 A457 F33 V36 K40 L50 Q53 V54 L57 R58 T205 F206 E209 A213 P19793 24801499 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4pp3 A 2.00 BS02 2VZ A 1 I268 A271 A272 Q275 F313 R316 L326 A327 I345 F346 C432 L436 I24 A27 A28 Q31 F69 R72 L82 A83 I101 F102 C188 L192 P19793 24801499 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4pp5 A 2.00 BS01 III B 1 F277 V280 K284 L294 Q297 V298 L301 R302 T449 F450 E453 E456 F33 V36 K40 L50 Q53 V54 L57 R58 T205 F206 E209 E212 P19793 24801499 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4pp5 A 2.00 BS02 2W0 A 1 I268 A271 A272 Q275 W305 F313 R316 L326 A327 V342 I345 C432 L436 I24 A27 A28 Q31 W61 F69 R72 L82 A83 V98 I101 C188 L192 P19793 24801499 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4pqg A 2.00 BS01 UDP A 1 G16 Y19 R328 K333 Y357 G358 H384 A385 L387 G407 L408 T409 E412 G19 Y22 R331 K336 Y360 G361 H387 A388 L390 G410 L411 T412 E415 2.4.1.- Q97P84 HHHMTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMILADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVLRVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAVLYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVILDRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFIVSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKHIDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYSQYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVEDQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD 4pqg A 2.00 BS02 NAG A 1 G16 V17 A20 H242 A243 V305 S403 E404 G405 F406 G407 G19 V20 A23 H245 A246 V308 S406 E407 G408 F409 G410 2.4.1.- Q97P84 HHHMTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMILADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVLRVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAVLYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVILDRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFIVSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKHIDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYSQYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVEDQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD 4pqg B 2.00 BS01 UDP B 1 S15 G16 Y19 R328 K333 Y357 G358 H384 A385 L387 G407 L408 T409 E412 S15 G16 Y19 R328 K333 Y357 G358 H384 A385 L387 G407 L408 T409 E412 2.4.1.- Q97P84 MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMILADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVLRVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAVLYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVILDRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFIVSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKHIDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYSQYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVEDQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVL 4pqg B 2.00 BS02 NAG B 1 G16 V17 A20 H242 A243 V305 S403 E404 G405 F406 G407 G16 V17 A20 H242 A243 V305 S403 E404 G405 F406 G407 2.4.1.- Q97P84 MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMILADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVLRVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAVLYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVILDRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFIVSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKHIDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYSQYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVEDQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVL 4pqk A 3.40 BS01 MLR A 1 D15 K16 E45 E46 W63 A64 D66 R67 E112 E154 P155 Y156 F157 W231 M331 S338 W341 Y342 R345 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 M330 S337 W340 Y341 R344 B1B3N6 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTHNFDDKEMLLQEFPEQLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHDRGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNM 4pqk B 3.40 BS01 MLR B 1 N13 D15 K16 E45 E46 W63 A64 D66 R67 E112 E154 P155 Y156 W231 M331 W341 Y342 R345 N12 D14 K15 E44 E45 W62 A63 D65 R66 E111 E153 P154 Y155 W230 M330 W340 Y341 R344 B1B3N6 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTHNFDDKEMLLQEFPEQLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHDRGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMK 4pqk C 3.40 BS01 MLR C 1 N13 D15 K16 E45 E46 W63 A64 D66 R67 E112 E154 P155 Y156 W231 W341 Y342 R345 N11 D13 K14 E43 E44 W61 A62 D64 R65 E110 E152 P153 Y154 W229 W339 Y340 R343 B1B3N6 IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTHNFDDKEMLLQEFPEQLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHDRGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKN 4pqk D 3.40 BS01 MLR D 1 D15 K16 E45 E46 W63 A64 D66 R67 E112 E154 P155 Y156 W231 M331 W341 Y342 R345 D13 K14 E43 E44 W61 A62 D64 R65 E110 E147 P148 Y149 W224 M324 W334 Y335 R338 B1B3N6 IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKEKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTHNFDDKEMLLQEFPEQLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHDRGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNM 4pqt A 2.05 BS01 ZN A 1 H356 C397 H404 H406 H108 C149 H156 H158 3.4.19.- Q9P371 24787148 KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVALHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR 4pqu A 2.51 BS01 NUC T 1 W24 F61 I63 L74 D76 R78 N81 E89 Q91 L92 G93 I94 G152 K154 P157 Y183 N265 R356 K374 N474 Q500 W24 F61 I63 L74 D76 R78 N81 E89 Q91 L92 G93 I94 G152 K154 P157 Y183 N265 R356 K374 N474 Q500 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu A 2.51 BS02 NUC P 1 Y183 M184 D185 D186 M230 G231 C258 G262 K263 W266 L289 H361 K451 T473 Q475 K476 Y501 Y183 M184 D185 D186 M230 G231 C258 G262 K263 W266 L289 H361 K451 T473 Q475 K476 Y501 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu A 2.51 BS03 DTP A 1 K65 R72 L74 D110 V111 G112 D113 A114 Y115 Q151 D185 K65 R72 L74 D110 V111 G112 D113 A114 Y115 Q151 D185 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu A 2.51 BS04 MG A 1 D110 V111 D185 D110 V111 D185 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu A 2.51 BS05 MG A 2 D110 D185 D186 D110 D185 D186 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu B 2.51 BS01 NUC P 1 Q394 K395 F416 Q378 K379 F400 2.7.7.49,2.7.7.7 P03366 24880687 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 4pqu C 2.51 BS01 NUC E 1 F61 I63 L74 D76 R78 N81 E89 Q91 G93 I94 G152 W153 K154 P157 Y183 N265 T286 A355 N474 F61 I63 L74 D76 R78 N81 E89 Q91 G93 I94 G152 W153 K154 P157 Y183 N265 T286 A355 N474 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu C 2.51 BS02 NUC F 1 Y183 D185 M230 G231 C258 K259 G262 K263 W266 L289 G359 H361 T473 Q475 Y501 Y183 D185 M230 G231 C258 K259 G262 K263 W266 L289 G359 H361 T473 Q475 Y501 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu C 2.51 BS03 DTP C 1 K65 R72 L74 D110 V111 G112 D113 A114 Y115 Q151 D185 K219 K65 R72 L74 D110 V111 G112 D113 A114 Y115 Q151 D185 K219 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu C 2.51 BS04 MG C 1 D110 V111 D185 D110 V111 D185 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu C 2.51 BS05 MG C 2 D110 D185 D186 D110 D185 D186 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGN 4pqu D 2.51 BS01 NUC F 1 Q394 K395 F416 Q379 K380 F401 2.7.7.49,2.7.7.7 P03366 24880687 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 4prl A 2.60 BS01 NAD A 1 Y101 I106 G153 V154 G155 H156 I157 Y175 D176 H205 T206 P207 T212 A233 A234 D259 H295 A297 Y298 Y101 I106 G153 V154 G155 H156 I157 Y175 D176 H205 T206 P207 T212 A233 A234 D259 H295 A297 Y298 1.1.1.290 C5G4U0 24794195 MKIAVFSPSESERKLVAATEKKFGCELKLIDESLSAENVDQVADCDGVLLKPLGNLDDEIVYKKLADYGIKSIGLRIVGTNTIDFDLAKKYHLTVTNVPVYSPRAIAEMAVTQAMYLNRKIGEFKANMDKGDFTNPDSLISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKVLAYDVIYNPEVEPYLTYADFDTVLKEADIISLHTPLLKSTENMIGKKQFAEMKNDAILINAARGELVDTAALIEALEKHEIAAAGLDTLAHESSYFFKKVDDAQIPADYKKLAAMPNVIVTPHSAYFTKTSVRNMIEISLRDTIALANGERAHFVVSR 4prl B 2.60 BS01 NAD B 1 Y101 I106 G153 V154 G155 H156 I157 Y175 D176 V177 H205 T206 P207 A233 A234 R235 D259 H295 A297 Y101 I106 G153 V154 G155 H156 I157 Y175 D176 V177 H205 T206 P207 A233 A234 R235 D259 H295 A297 1.1.1.290 C5G4U0 24794195 MKIAVFSPSESERKLVAATEKKFGCELKLIDESLSAENVDQVADCDGVLLKPLGNLDDEIVYKKLADYGIKSIGLRIVGTNTIDFDLAKKYHLTVTNVPVYSPRAIAEMAVTQAMYLNRKIGEFKANMDKGDFTNPDSLISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKVLAYDVIYNPEVEPYLTYADFDTVLKEADIISLHTPLLKSTENMIGKKQFAEMKNDAILINAARGELVDTAALIEALEKHEIAAAGLDTLAHESSYFFKKVDDAQIPADYKKLAAMPNVIVTPHSAYFTKTSVRNMIEISLRDTIALANGERAHFVVSR 4ptz C 1.90 BS01 FMN C 1 S8 R10 S13 R14 S15 P74 V75 Y76 K77 A78 T106 G107 G108 T109 H112 D140 S9 R11 S14 R15 S16 P75 V76 Y77 K78 A79 T107 G108 G109 T110 H113 D141 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALHR 4ptz C 1.90 BS02 FMN C 2 R10 R14 K77 G108 T109 Y146 R11 R15 K78 G109 T110 Y147 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALHR 4ptz A 1.90 BS01 FMN A 1 S8 R10 S13 R14 S15 P74 V75 Y76 K77 A78 T106 G107 G108 T109 H112 D140 S9 R11 S14 R15 S16 P75 V76 Y77 K78 A79 T107 G108 G109 T110 H113 D141 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4ptz A 1.90 BS02 FMN A 2 R10 R14 K77 G108 T109 D140 Y146 R11 R15 K78 G109 T110 D141 Y147 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4ptz A 1.90 BS03 FMN B 1 F51 E93 F52 E94 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4ptz B 1.90 BS01 FMN A 3 F51 E93 F52 E94 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4ptz B 1.90 BS02 FMN B 2 S8 R10 S13 R14 S15 P74 V75 Y76 K77 A78 T106 G107 G108 T109 H112 D140 S9 R11 S14 R15 S16 P75 V76 Y77 K78 A79 T107 G108 G109 T110 H113 D141 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4ptz B 1.90 BS03 FMN B 1 R10 R14 K77 G108 T109 R11 R15 K78 G109 T110 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4ptz D 1.90 BS01 FMN D 1 S8 R10 S13 R14 S15 P74 V75 Y76 K77 A78 T106 G107 G108 T109 H112 D140 S9 R11 S14 R15 S16 P75 V76 Y77 K78 A79 T107 G108 G109 T110 H113 D141 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALHR 4pu0 C 2.30 BS01 FMN C 1 S8 S13 R14 S15 P74 V75 Y76 K77 T106 G107 G108 T109 H112 D140 S9 S14 R15 S16 P75 V76 Y77 K78 T107 G108 G109 T110 H113 D141 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4pu0 A 2.30 BS01 FMN A 1 S8 S13 R14 S15 P74 V75 Y76 K77 A78 T106 G107 G108 T109 H112 D140 S9 S14 R15 S16 P75 V76 Y77 K78 A79 T107 G108 G109 T110 H113 D141 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4pu0 B 2.30 BS01 FMN A 1 F51 D89 E93 F52 D90 E94 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4pu0 D 2.30 BS01 FMN D 1 S8 R10 S13 R14 S15 P74 V75 Y76 K77 A78 T106 G107 G108 T109 H112 D140 S9 R11 S14 R15 S16 P75 V76 Y77 K78 A79 T107 G108 G109 T110 H113 D141 1.5.1.38 P80644 24816272 MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALH 4puo A 2.90 BS01 NUC T 1 F61 I63 R78 L283 G285 R448 Q500 F62 I64 R79 L284 G286 R449 Q501 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4puo A 2.90 BS02 NUC P 1 Y183 M230 G231 K259 G262 A360 H361 R448 K451 T473 Q475 K476 Y501 Y184 M231 G232 K260 G263 A361 H362 R449 K452 T474 Q476 K477 Y502 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4puo A 2.90 BS03 NVP A 1 L100 K101 V106 V179 Y181 Y188 F227 W229 L234 P236 Y318 L101 K102 V107 V180 Y182 Y189 F228 W230 L235 P237 Y319 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4puo B 2.90 BS01 NUC P 1 K395 N418 K379 N402 2.7.7.49,2.7.7.7 P03366 24880687 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 4puo C 2.90 BS01 NUC E 1 I63 R78 E89 A446 R448 N474 I64 R79 E90 A447 R449 N475 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4puo C 2.90 BS02 NUC F 1 M230 G231 Q242 N255 C258 K259 G262 K263 W266 R358 G359 A360 H361 K451 T473 Q475 Y501 M231 G232 Q243 N256 C259 K260 G263 K264 W267 R359 G360 A361 H362 K452 T474 Q476 Y502 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4puo C 2.90 BS03 NVP C 1 L100 K101 V106 V179 Y181 Y188 W229 L234 H235 P236 Y318 L101 K102 V107 V180 Y182 Y189 W230 L235 H236 P237 Y319 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4puo D 2.90 BS01 NUC F 1 K395 N418 K379 N402 2.7.7.49,2.7.7.7 P03366 24880687 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 4pwd A 3.00 BS01 NUC T 1 G93 N265 L283 R284 G285 K374 G94 N266 L284 R285 G286 K375 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4pwd A 3.00 BS02 NUC P 1 Y183 M230 G231 K259 G262 W266 L289 R358 G359 A360 H361 K451 T473 Q475 K476 Y501 Y184 M231 G232 K260 G263 W267 L290 R359 G360 A361 H362 K452 T474 Q476 K477 Y502 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4pwd A 3.00 BS03 NVP A 1 L100 K101 V106 V179 Y181 Y188 W229 L234 Y318 L101 K102 V107 V180 Y182 Y189 W230 L235 Y319 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4pwd A 3.00 BS04 CA A 1 D443 N498 D549 D444 N499 D550 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4pwd B 3.00 BS01 NUC P 1 Q394 K395 Q378 K379 2.7.7.49,2.7.7.7 P03366 24880687 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 4pwd C 3.00 BS01 NUC E 1 L92 G93 I94 N265 L283 G285 R356 K374 N474 E478 Q500 Y501 L93 G94 I95 N266 L284 G286 R357 K375 N475 E479 Q501 Y502 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4pwd C 3.00 BS02 NUC F 1 Y183 M230 G231 Q242 C258 K259 G262 K263 W266 R358 G359 A360 H361 K451 T473 Q475 Y501 Y184 M231 G232 Q243 C259 K260 G263 K264 W267 R359 G360 A361 H362 K452 T474 Q476 Y502 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4pwd C 3.00 BS03 NVP C 1 K101 V106 V179 Y181 Y188 W229 L234 H235 P236 Y318 K102 V107 V180 Y182 Y189 W230 L235 H236 P237 Y319 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4pwd C 3.00 BS04 CA C 1 D443 G444 D549 D444 G445 D550 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4pwd D 3.00 BS01 NUC F 1 K395 N418 K379 N402 2.7.7.49,2.7.7.7 P03366 24880687 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 4pyl A 2.20 BS01 MG A 1 D184 K187 D212 N213 D138 K141 D166 N167 2.1.1.6 P22734 TKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGPS 4pyl A 2.20 BS02 SFG A 1 M83 N84 V85 G109 A110 Y111 Y114 S115 E133 M134 Y138 G160 A161 S162 Q163 F182 D184 H185 W186 M37 N38 V39 G63 A64 Y65 Y68 S69 E87 M88 Y92 G114 A115 S116 Q117 F136 D138 H139 W140 2.1.1.6 P22734 TKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGPS 4pyl A 2.20 BS03 TCW A 1 W81 M83 D184 W186 K187 D212 N213 P217 E242 W35 M37 D138 W140 K141 D166 N167 P171 E196 2.1.1.6 P22734 TKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGPS 4pys A 1.82 BS01 ZN A 1 C254 C272 C313 C316 C235 C248 C287 C290 Q5LAT3 GQIIMPTPGKIERADGRLRLQGKIRMYAEESPGSFIRLFYEKLVPESAVEWCKEEVNSHISWKKDVTLPTEGYRIRVTPERIIVEAADDAGFIYAIQSLRQWNTGEERGLIFPCVEITDFPRVKWRSFMLDSGRQYQKVSTIKKYIDMASMLKMNYFHWHLTEGLGWRIEIKRYPFLTRIGAFVGQGPEQQGFYSQEEVKEIIGYAADRGITVVPEIDMPGHAEAALNAYPRLGCFNVAVKVPQNIFCAGKDSTLIFLKNVLDEVCRMFPSAYIHLGGDPKGNWDKCPDCRSRIEKEKLKDSHDLQLWFSARMADYLKQKGRKAIFWGDVIYKDGYSLPDNVVIQWWNWRGHRDLALKNAVRHNYPVICGTNYYTYLNFPLTPWKGYTQARTFDLEDVYLRNPSYRPREENPLILGMSSALWTDDGVTESMIDRRVFPRILALAEQMWHSGNPENFDEFYGKVLSKQLWFEQQGYSFGPALKEDAGTNYKWD 4pys B 1.82 BS01 ZN B 1 C254 C272 C313 C316 C235 C245 C281 C284 Q5LAT3 GQIIMPTPGKIERADGRLRLQGKIRMYAEESPGSFIRLFYEKLVPESAVEWCKEEVNSHISWKKDVTLPTEGYRIRVTPERIIVEAADDAGFIYAIQSLRQWNTGEERGLIFPCVEITDFPRVKWRSFMLDSGRQYQKVSTIKKYIDMASMLKMNYFHWHLTEGLGWRIEIKRYPFLTRIGAFVGQGPEQQGFYSQEEVKEIIGYAADRGITVVPEIDMPGHAEAALNAYPRLGCNVAVKVNIFCAGKDSTLIFLKNVLDEVCRMFPSAYIHLGGDEAPKCPDCRSRIEKEKLSHDLQLWFSARMADYLKQKGRKAIFWGDVIYKDYSLPDNVVIQWWNWRGHRDLALKNAVRHNYPVICGTNYYTYLNFPLTPWKGYTQARTFDLEDVYLRNPSYRPREENPLILGMSSALWTDDGVTESMIDRRVFPRILALAEQMWHSGNPENFDEFYGKVLSKQLWFEQQGYSFGPALKEDAGTNYKWD 4q0b A 3.30 BS01 NUC T 1 F61 I63 F62 I64 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b A 3.30 BS02 NUC t 1 R448 Q500 R449 Q501 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b A 3.30 BS03 NUC P 1 Y183 M230 G231 N255 K259 G262 K263 W266 L289 R358 G359 A360 H361 R448 T473 Q475 K476 Y501 Y184 M231 G232 N256 K260 G263 K264 W267 L290 R359 G360 A361 H362 R449 T474 Q476 K477 Y502 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b A 3.30 BS04 NVP A 1 L100 K101 K103 V106 V179 Y181 Y188 W229 L234 P236 L101 K102 K104 V107 V180 Y182 Y189 W230 L235 P237 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b A 3.30 BS05 MN A 1 D443 G444 E478 N498 D549 D444 G445 E479 N499 D550 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b C 3.30 BS01 NUC E 1 I63 E89 G285 I64 E90 G286 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b C 3.30 BS02 NUC F 1 M230 G231 C258 K259 G262 K263 L289 R358 G359 A360 H361 K451 T473 Q475 K476 Y501 M231 G232 C259 K260 G263 K264 L290 R359 G360 A361 H362 K452 T474 Q476 K477 Y502 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b C 3.30 BS03 NUC e 1 R448 N474 E478 Q500 Y501 R449 N475 E479 Q501 Y502 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b C 3.30 BS04 NVP C 1 L100 K101 K103 V106 V179 Y181 Y188 W229 L234 H235 P236 Y318 L101 K102 K104 V107 V180 Y182 Y189 W230 L235 H236 P237 Y319 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b C 3.30 BS05 MN C 1 D443 G444 E478 D549 D444 G445 E479 D550 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03366 24880687 VPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4q0b D 3.30 BS01 NUC F 1 K395 N418 K379 N402 2.7.7.49,2.7.7.7 P03366 24880687 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 4q5t A 1.91 BS01 MET A 1 Y69 F86 Q87 H88 F91 S112 N147 R150 N206 N235 Y46 F63 Q64 H65 F68 S89 N124 R127 N183 N212 I6L927 GQKNDKNTLTVGVMTMTDSDKERWDKIEELLKKENIKLKFKEFTDYSQPNKALKNGEIDINSFQHYNFLNNWNKENKGDLVTVAETYISPINLFSGTENGKAKYSSAKEIPNGGQIAIPNDATNESRALYVLQDAGLIKLNVSGDELATVKNIKSNPKNLDIKEVDASQTARNLASVDAAVVNNSYAVPAKIDFKTSLYKEKVNEGSKQWINIIAAQKNWKKSKKAAAIKKLIKAYHTDAVKKVIKKTAKGVDEPVW 4q94 A 1.85 BS01 III C 1 N18 S19 Q20 V23 Y61 N64 D65 Q68 K71 N17 S18 Q19 V22 Y60 N63 D64 Q67 K70 Q9NQG5 SSFSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSME 4q94 A 1.85 BS02 III D 1 R106 L107 I110 R114 S115 R105 L106 I109 R113 S114 Q9NQG5 SSFSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSME 4q94 B 1.85 BS01 III C 1 R106 L107 I110 R114 S115 R105 L106 I109 R113 S114 Q9NQG5 SSFSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSME 4q94 B 1.85 BS02 III D 1 N18 S19 Q20 V23 Y61 N64 D65 Q68 K71 N17 S18 Q19 V22 Y60 N63 D64 Q67 K70 Q9NQG5 SSFSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSME 4qby G 3.00 BS01 MG G 1 T8 Y119 R122 A123 M125 T7 Y118 R121 A122 M124 3.4.25.1 P21243 GYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIAEQ 4qby H 3.00 BS01 III 1 1 T1 S20 T21 Q22 G45 A46 G47 A49 T1 S20 T21 Q22 G45 A46 G47 A49 3.4.25.1 P25043 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 4qby I 3.00 BS01 III 1 1 D124 L125 D124 L125 3.4.25.1 P25451 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 4qby I 3.00 BS02 MG I 1 A174 D177 S180 A174 D177 S180 3.4.25.1 P25451 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 4qby I 3.00 BS03 MG I 2 R27 W182 D204 R27 W182 D204 3.4.25.1 P25451 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 4qby J 3.00 BS01 MG J 1 Q118 D120 T124 Q118 D120 T124 3.4.25.1 P22141 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDF 4qby K 3.00 BS01 III 2 1 T1 A20 T21 K33 M45 A46 G47 A49 T1 A20 T21 K33 M45 A46 G47 A49 3.4.25.1 P30656 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4qby K 3.00 BS02 MG K 1 A165 H166 D168 A169 S171 A165 H166 D168 A169 S171 3.4.25.1 P30656 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4qby K 3.00 BS03 MG K 2 I82 N85 L86 I82 N85 L86 3.4.25.1 P30656 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4qby L 3.00 BS01 III 2 1 D126 V128 D126 V128 3.4.25.1 P23724 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 4qby N 3.00 BS01 MG N 1 R19 I163 D166 S169 R19 I163 D166 S169 3.4.25.1 P38624 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL 4qby V 3.00 BS01 III 3 1 T1 S20 T21 Q22 G45 A46 G47 A49 T1 S20 T21 Q22 G45 A46 G47 A49 3.4.25.1 P25043 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 4qby V 3.00 BS02 MG V 1 R19 I163 D166 L167 S169 R19 I163 D166 L167 S169 3.4.25.1 P25043 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 4qby W 3.00 BS01 III 3 1 D124 L125 D124 L125 3.4.25.1 P25451 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 4qby Y 3.00 BS01 III 4 1 T1 A20 T21 K33 M45 A46 G47 A49 T1 A20 T21 K33 M45 A46 G47 A49 3.4.25.1 P30656 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4qby Y 3.00 BS02 MG I 3 H166 A169 H166 A169 3.4.25.1 P30656 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4qby Y 3.00 BS03 MG Y 1 R19 A165 H166 D168 A169 S171 R19 A165 H166 D168 A169 S171 3.4.25.1 P30656 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4qby Z 3.00 BS01 III 4 1 D126 V128 D126 V128 3.4.25.1 P23724 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 4qby Z 3.00 BS02 MG Z 1 R28 T192 H195 I196 V198 D222 R28 T192 H195 I196 V198 D222 3.4.25.1 P23724 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 4qem A 1.20 BS01 HC4 A 1 F5 G30 C45 H48 D49 F5 G29 C44 H47 D48 3.1.1.4 D0VX11 SLLEFGKMILEETGKLAIPSYSSYGCYCGWGGKGTPKDATDRCCFVHDCCYGNLPDCNPKSDRYKYKRVNGAIVCEKGTSCENRICECDKAAAICFRQNLNTYSKKYMLYPDFLCKGELKC 4qer A 1.20 BS01 STL A 1 L2 F5 G6 I19 Y22 G30 C45 H48 D49 L2 F5 G6 I18 Y21 G29 C44 H47 D48 3.1.1.4 D0VX11 SLLEFGKMILEETGKLAIPSYSSYGCYCGWGGKGTPKDATDRCCFVHDCCYGNLPDCNPKSDRYKYKRVNGAIVCEKGTSCENRICECDKAAAICFRQNLNTYSKKYMLYPDFLCKGELKC 4qez B 2.70 BS01 ADE B 1 A77 G78 F152 M153 V172 E173 S197 D198 A200 A76 G77 F146 M147 V166 E167 S191 D192 A194 3.2.2.9 Q81LL4 RIAVIGAMEEEVRILRDKLEQAETETVAGCEFTKGQLAGHEVILLKSGIGKVNAAMSTTILLERYKPEKVINTGSAGGFHHSLNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADEALVALAEKCMQQVVKGMIATGDSFMSDPNRVAAIRDKFENLYAVEMEAAAVAQVCHQYEVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLEELKLEHHHH 4qez A 2.70 BS01 ADE A 1 A77 G78 F152 M153 V172 E173 S197 D198 A76 G77 F145 M146 V165 E166 S190 D191 3.2.2.9 Q81LL4 RIAVIGAMEEEVRILRDKLEQAETETVAGCEFTKGQLAGHEVILLKSGIGKVNAAMSTTILLERYKPEKVINTGSAGGFHHSLNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADEALVALAEKCMQVVKGMIATGDSFMSDPNRVAAIRDKFENLYAVEMEAAAVAQVCHQYEVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLEEL 4qez C 2.70 BS01 ADE C 1 A77 G78 F152 M153 V172 E173 S197 D198 F208 A76 G77 F146 M147 V166 E167 S191 D192 F202 3.2.2.9 Q81LL4 RIAVIGAMEEEVRILRDKLEQAETETVAGCEFTKGQLAGHEVILLKSGIGKVNAAMSTTILLERYKPEKVINTGSAGGFHHSLNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADEALVALAEKCMQQVVKGMIATGDSFMSDPNRVAAIRDKFENLYAVEMEAAAVAQVCHQYEVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLEELKLEHHHH 4qf7 A 1.48 BS01 C0R A 1 L2 L3 F5 G6 A18 I19 Y22 S23 C29 G30 L2 L3 F5 G6 A17 I18 Y21 S22 C28 G29 3.1.1.4 D0VX11 SLLEFGKMILEETGKLAIPSYSSYGCYCGWGGKGTPKDATDRCCFVHDCCYGNLPDCNPKSDRYKYKRVNGAIVCEKGTSCENRICECDKAAAICFRQNLNTYSKKYMLYPDFLCKGELKC 4qf8 A 1.65 BS01 SPD A 1 F5 G6 A18 Y22 Y28 C29 G30 C45 H48 D49 F5 G6 A17 Y21 Y27 C28 G29 C44 H47 D48 3.1.1.4 D0VX11 SLLEFGKMILEETGKLAIPSYSSYGCYCGWGGKGTPKDATDRCCFVHDCCYGNLPDCNPKSDRYKYKRVNGAIVCEKGTSCENRICECDKAAAICFRQNLNTYSKKYMLYPDFLCKGELKC 4qfh A 1.80 BS01 G6P A 1 I206 G208 S209 S259 K260 T261 T264 Q408 E412 K572 I209 G211 S212 S262 K263 T264 T267 Q411 E415 K575 5.3.1.9 O61113 HHHMKDQYLKDLTVHLNESNAAPANTSMAVASFNMPHEITRRMRPLGVDADTSLTSCPSWRRLQELYEIHGSESILKNFDECKDRFQRYSLEVDLRSSDKNFVFLDYSKTHINDEIKDVLFKLVEERGIRAFMRALFAGEKVNTAENRSVLHIALRNRSNRPIFVNGHDVMPLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMACEALRPFSDRRISMHFVSNIDGTHLSEVLNLVDLESTLFIIASKTFTTQETITNALSARNEFLKFLSSRGISEAGAVAKHFVALSTNAEKVKEFGIDEENMFQFWDWVGGRYSLWSAIGLSVMISIGYDNFVELLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAILPYDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGTKLIPCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQLLIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVELGKLLAKSILLQLQPGQKVTNHDSSTNGLIELFNERSH 4qfh B 1.80 BS01 G6P B 1 I206 G208 S209 S259 K260 T261 T264 E412 K572 I210 G212 S213 S263 K264 T265 T268 E416 K576 5.3.1.9 O61113 HHHHMKDQYLKDLTVHLNESNAAPANTSMAVASFNMPHEITRRMRPLGVDADTSLTSCPSWRRLQELYEIHGSESILKNFDECKDRFQRYSLEVDLRSSDKNFVFLDYSKTHINDEIKDVLFKLVEERGIRAFMRALFAGEKVNTAENRSVLHIALRNRSNRPIFVNGHDVMPLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMACEALRPFSDRRISMHFVSNIDGTHLSEVLNLVDLESTLFIIASKTFTTQETITNALSARNEFLKFLSSRGISEAGAVAKHFVALSTNAEKVKEFGIDEENMFQFWDWVGGRYSLWSAIGLSVMISIGYDNFVELLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAILPYDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGTKLIPCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQLLIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVELGKLLAKSILLQLQPGQKVTNHDSSTNGLIELFNERSH 4qgd A 1.80 BS01 PZZ A 1 L2 L3 F5 G6 I9 A18 I19 Y22 S23 C29 G30 L2 L3 F5 G6 I9 A17 I18 Y21 S22 C28 G29 3.1.1.4 D0VX11 SLLEFGKMILEETGKLAIPSYSSYGCYCGWGGKGTPKDATDRCCFVHDCCYGNLPDCNPKSDRYKYKRVNGAIVCEKGTSCENRICECDKAAAICFRQNLNTYSKKYMLYPDFLCKGELKC 4qgl A 2.61 BS01 CD A 1 H99 H101 E105 H144 H103 H105 E109 H148 1.13.11.54,1.13.11.53 Q81MI9 GAAAMAQIRIHEVNTRIENEVKVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSARRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY 4qgl A 2.61 BS02 CD A 2 G-3 H113 E131 G1 H117 E135 1.13.11.54,1.13.11.53 Q81MI9 GAAAMAQIRIHEVNTRIENEVKVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSARRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY 4qgm A 2.97 BS01 CD A 1 H99 H101 E105 H144 H102 H104 E108 H147 1.13.11.54,1.13.11.53 Q81MI9 AAAMAQIRIHEVNTRIENEVKVSKFLQEEGVLYEKWNISKLPPHLNENYSLTDENKAEILAVFSKEIADVSARRGYKAHDVISLSNSTPNLDELLINFQKEHHHTDDEVRFIVSGHGIFAIEGKDGTFFDVELEPGDLISVPENARHYFTLQDDRQVVAIRIFVTTEGWVPIY 4qgr A 1.75 BS01 PLP A 1 N57 G58 T59 T83 F84 A86 V136 D162 A164 Q165 S186 K191 N60 G61 T62 T86 F87 A89 V139 D165 A167 Q168 S189 K194 Q2YRB9 HHHMQFIDLGAQRARIENRLNAAISKVVAEGRYILGPEVAEFEKKLGEYLGVEHVIACANGTDALQMPLMTRGIGPGHAVFVPSFTFAATAEVVALVGAEPVFVDVDPDSYNMNVEQLEAAIAATIKEGRLEPKAIIPVDLFGLAASYNRITAIAEREGLFIIEDAAQSIGGKRDNVMCGAFGHVGATSFYPAKPLGCYGDGGAMFTNDAELADTLRSVLFHGKGETQYDNVRIGINSRLDTIQAAVLLEKLAILEDEMEARDRIARRYNEALKDVVKVPELPAGNRSAWAQYSIESENRDGLKAQLQAEGIPSVIYYVKPLHLQTAYKHYSVAPGGLPVSESLPSRILSLPMHPYLSEADQDKIIGVIRGFHGKK 4qgr B 1.75 BS01 PLP B 1 G58 T59 T83 F84 A86 V136 D162 A164 Q165 S186 K191 G59 T60 T84 F85 A87 V137 D163 A165 Q166 S187 K192 Q2YRB9 HMQFIDLGAQRARIENRLNAAISKVVAEGRYILGPEVAEFEKKLGEYLGVEHVIACANGTDALQMPLMTRGIGPGHAVFVPSFTFAATAEVVALVGAEPVFVDVDPDSYNMNVEQLEAAIAATIKEGRLEPKAIIPVDLFGLAASYNRITAIAEREGLFIIEDAAQSIGGKRDNVMCGAFGHVGATSFYPAKPLGCYGDGGAMFTNDAELADTLRSVLFHGKGETQYDNVRIGINSRLDTIQAAVLLEKLAILEDEMEARDRIARRYNEALKDVVKVPELPAGNRSAWAQYSIESENRDGLKAQLQAEGIPSVIYYVKPLHLQTAYKHYSVAPGGLPVSESLPSRILSLPMHPYLSEADQDKIIGVIRGFHGK 4qhq A 1.40 BS01 MET A 1 Y68 F85 Q86 H87 Y90 Y109 S111 N140 R143 N202 N204 N229 Y38 F55 Q56 H57 Y60 Y79 S81 N110 R113 N172 N174 N199 B4EA88 VIKVGTVAGPDSEVWQVVQKVAKEKEGLNVKVIEFNDYVQPNAALDSGDLDANSFQHQPYLDSQVKQRGYKIVSAGLTYISPIGVYSKKFKSLKDLPQGAKLAVPNDPSNENRALLLLQTQGVIKLKAGAGTGGNNATVLDIAENPKKLKISELDAAQLPRVLSDVDAAVINTNYALAANLQPTKDAIALESLTSPYANLIAVRAKDKDQPWVKKLVKAYQSPEVKEFIKKQFKGSMVASF 4qjq A 2.10 BS01 HEM A 1 M101 G104 Q105 D108 D112 F113 A114 R255 E258 Q259 T344 F347 R348 G350 H351 F380 L417 L433 I436 R440 M101 G104 Q105 D108 D112 F113 A114 R255 E258 Q259 T344 F347 R348 G350 H351 F380 L417 L433 I436 R440 1.11.1.7 A3F9D6 SWEVGCGAPVPLVTCDEQSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCVQGDECFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELRNKLFQPTHKVHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 4qjq A 2.10 BS02 CA A 1 D110 T184 F186 D188 S190 D110 T184 F186 D188 S190 1.11.1.7 A3F9D6 SWEVGCGAPVPLVTCDEQSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCVQGDECFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELRNKLFQPTHKVHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 4qjq A 2.10 BS03 OTR A 1 H109 R255 E258 F381 Q423 P424 H109 R255 E258 F381 Q423 P424 1.11.1.7 A3F9D6 SWEVGCGAPVPLVTCDEQSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCVQGDECFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELRNKLFQPTHKVHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 4tkr A 3.00 BS01 TPP A 1 S23 S31 S32 S34 S36 W61 H65 E82 Y83 F87 R127 H131 G135 W139 F152 S153 N157 S21 S29 S30 S32 S34 W59 H63 E80 Y81 F85 R125 H129 G133 W137 F150 S151 N155 S5L6I0 NKRLIILLECAIFAAVAMVLSFIPLDIGSSFSISLGMIPMYVIAIRRGFWAAGFAGLLWGLLHFLTGKAYILMPSQAIIEYILAFSFIAFSGVFSKQVRSNLAANQLKKAIEWAWGTMIIGGVARYFWHYVAGVLFWGAYAFQGWGAQLFSIVMNGASCLGTVLVSGIIISILLKTSPKLFLP 4tkr B 3.00 BS01 TPP B 1 S23 S31 S32 S34 S36 H65 E82 Y83 R127 H131 G135 W139 F152 N157 S24 S32 S33 S35 S37 H66 E83 Y84 R128 H132 G136 W140 F153 N158 S5L6I0 VMQNKRLIILLECAIFAAVAMVLSFIPLDIGSSFSISLGMIPMYVIAIRRGFWAAGFAGLLWGLLHFLTGKAYILMPSQAIIEYILAFSFIAFSGVFSKQVRSNLAANQLKKAIEWAWGTMIIGGVARYFWHYVAGVLFWGAYAFQGWGAQLFSIVMNGASCLGTVLVSGIIISILLKTSPKLFLP