3wic A 2.60 BS01 ZN A 1 C41 H68 E69 C40 H67 E68 1.1.1.47 Q979W2 STINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDNNYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGTNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQKPKGEIKTVIKWP 3wic A 2.60 BS02 ZN A 2 C99 C102 C110 D116 C98 C101 C109 D115 1.1.1.47 Q979W2 STINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDNNYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGTNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQKPKGEIKTVIKWP 3wid A 2.25 BS02 NAP A 1 I192 S194 G195 E197 N216 R217 H218 Y238 T252 S253 T258 F275 G276 F277 S304 V305 D306 I191 S193 G194 E196 N215 R216 H217 Y237 T251 S252 T257 F274 G275 F276 S303 V304 D305 1.1.1.47 Q979W2 STINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDNNYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQKPKGEIKTVIKWP 3wid B 2.25 BS02 NAP B 1 N160 I192 S194 G195 S196 E197 N216 R217 H218 Y238 T252 S253 D255 T258 F275 F277 S304 V305 D306 N159 I191 S193 G194 S195 E196 N215 R216 H217 Y237 T251 S252 D254 T257 F274 F276 S303 V304 D305 1.1.1.47 Q979W2 STINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDNNYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQKPKGEIKTVIKWP 3wid D 2.25 BS02 NAP D 1 N160 I192 S194 G195 S196 E197 N216 R217 H218 Y238 T252 S253 T258 F275 G276 F277 S304 V305 D306 N159 I191 S193 G194 S195 E196 N215 R216 H217 Y237 T251 S252 T257 F274 G275 F276 S303 V304 D305 1.1.1.47 Q979W2 STINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDNNYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQKPKGEIKTVIKWP 3wie A 2.33 BS04 BGC A 1 T43 H68 E119 E156 K159 N160 F277 V305 D306 T42 H67 E118 E155 K158 N159 F276 V304 D305 1.1.1.47 Q979W2 STINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDNNYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQKPKGEIKTVIKWP 3wie B 2.33 BS04 BGC B 1 T43 H68 V93 E119 E156 K159 N160 D306 T42 H67 V92 E118 E155 K158 N159 D305 1.1.1.47 Q979W2 STINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDNNYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQKPKGEIKTVIKWP 3wie C 2.33 BS04 BGC C 1 T43 V93 R94 E119 E156 K159 N160 D306 T42 V92 R93 E118 E155 K158 N159 D305 1.1.1.47 Q979W2 STINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDNNYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQKPKGEIKTVIKWP 3wie D 2.33 BS04 BGC D 1 T43 E119 E156 K159 N160 F277 V305 D306 T42 E118 E155 K158 N159 F276 V304 D305 1.1.1.47 Q979W2 STINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSDNNYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDETENKMKMMDDFGVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKPEETNIFFQKPKGEIKTVIKWP 3wnz A 1.90 BS01 ADP A 1 K138 I176 K178 A183 S184 S185 V188 E226 E227 F228 L229 Q268 F271 E311 I323 E324 K135 I173 K175 A180 S181 S182 V185 E223 E224 F225 L226 Q265 F268 E308 I320 E321 6.3.2.28 P39641 24702628 KTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHNKPEEEVVEQIVKVAEMFGADAITTNNELFIAPMAKACERLGLRGAGVQAAENARDKNKMRDAFNKAGVKSIKNKRVTTLEDFRAALEEIGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVTFEAPFIAEEFLQGEYGDWYQTEGYSDYISIEGIMADGEYFPIAIHDKTPQIGFTETSHITPSILDEEAKKKIVEAAKKANEGLGLQNCATHTEIKLMKNREPGLIESAARFAGWNMIPNIKKVFGLDMAQLLLDVLCFGKDADLPDGLLDQEPYYVADCHLYPQHFKQNGQIPETAEDLVIEAIDIPDGLLKGDTEIVSFSAAAPGTSVDLTLFEAFNSIAAFELKGSNSQDVAESIRQIQQHAKLTAKY 3wo0 A 2.00 BS03 MG A 2 K138 E324 K135 E321 6.3.2.28 P39641 24702628 KTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHNKPEEEVVEQIVKVAEMFGADAITTNNELFIAPMAKACERLGLRGAGVQAAENARDKNKMRDAFNKAGVKSIKNKRVTTLEDFRAALEEIGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVTFEAPFIAEEFLQGEYGDWYQTEGYSDYISIEGIMADGEYFPIAIHDKTPQIGFTETSHITPSILDEEAKKKIVEAAKKANEGLGLQNCATHTEIKLMKNREPGLIESAARFAGWNMIPNIKKVFGLDMAQLLLDVLCFGKDADLPDGLLDQEPYYVADCHLYPQHFKQNGQIPETAEDLVIEAIDIPDGLLKGDTEIVSFSAAAPGTSVDLTLFEAFNSIAAFELKGSNSQDVAESIRQIQQHAKLTAKY 3wo0 A 2.00 BS04 ALA A 1 E273 H309 E311 R328 G331 W332 M334 E270 H306 E308 R325 G328 W329 M331 6.3.2.28 P39641 24702628 KTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHNKPEEEVVEQIVKVAEMFGADAITTNNELFIAPMAKACERLGLRGAGVQAAENARDKNKMRDAFNKAGVKSIKNKRVTTLEDFRAALEEIGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVTFEAPFIAEEFLQGEYGDWYQTEGYSDYISIEGIMADGEYFPIAIHDKTPQIGFTETSHITPSILDEEAKKKIVEAAKKANEGLGLQNCATHTEIKLMKNREPGLIESAARFAGWNMIPNIKKVFGLDMAQLLLDVLCFGKDADLPDGLLDQEPYYVADCHLYPQHFKQNGQIPETAEDLVIEAIDIPDGLLKGDTEIVSFSAAAPGTSVDLTLFEAFNSIAAFELKGSNSQDVAESIRQIQQHAKLTAKY 3wo1 A 2.30 BS01 ADP A 1 K138 K178 A183 S184 S185 E226 E227 F228 L229 Q268 E311 E324 K136 K176 A181 S182 S183 E224 E225 F226 L227 Q266 E309 E322 6.3.2.28 P39641 24702628 SKTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHNKPEEEVVEQIVKVAEMFGADAITTNNELFIAPMAKACERLGLRGAGVQAAENARDKNKMRDAFNKAGVKSIKNKRVTTLEDFRAALEEIGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVTFEAPFIAEEFLQGEYGDWYQTEGYSDYISIEGIMADGEYFPIAIHDKTPQIGFTETSHITPSILDEEAKKKIVEAAKKANEGLGLQNCATHTEIKLMKNREPGLIESAARFAGANMIPNIKKVFGLDMAQLLLDVLCFGKDADLPDGLLDQEPYYVADCHLYPQHFKQNGQIPETAEDLVIEAIDIPDGLLKGDTEIVSFSAAAPGTSVDLTLFEAFNSIAAFELKGSNSQDVAESIRQIQQHAKLTAKY 3wo1 A 2.30 BS04 ALA A 1 E273 H309 E311 R328 A330 G331 M334 E271 H307 E309 R326 A328 G329 M332 6.3.2.28 P39641 24702628 SKTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHNKPEEEVVEQIVKVAEMFGADAITTNNELFIAPMAKACERLGLRGAGVQAAENARDKNKMRDAFNKAGVKSIKNKRVTTLEDFRAALEEIGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVTFEAPFIAEEFLQGEYGDWYQTEGYSDYISIEGIMADGEYFPIAIHDKTPQIGFTETSHITPSILDEEAKKKIVEAAKKANEGLGLQNCATHTEIKLMKNREPGLIESAARFAGANMIPNIKKVFGLDMAQLLLDVLCFGKDADLPDGLLDQEPYYVADCHLYPQHFKQNGQIPETAEDLVIEAIDIPDGLLKGDTEIVSFSAAAPGTSVDLTLFEAFNSIAAFELKGSNSQDVAESIRQIQQHAKLTAKY 3zoc A 2.10 BS01 FMN A 1 T12 N24 M26 A27 A28 D29 W30 A44 V45 A46 R49 T50 T51 W75 A77 G78 K80 K81 G82 K85 H155 W158 F161 T16 N28 M30 A31 A32 D33 W34 A48 V49 A50 R53 T54 T55 W79 A81 G82 K84 K85 G86 K89 H159 W162 F165 O58586 YFQGMEGYRLLYPMRTYLIVSGHGEETNVMAADWVTVVSFDPFIVGVAVAPKRTTHKLIKKYGEFVISVPSLDVLRDVWIAGTKKGPSKLKEMSVTLIPSKKVKVPSIEEALANIECRVIDARSYGDHTFFVGEVVGYTYKDYAFEKGKPNLKAKFLAHVSWSEFVTFSEKVHKAE 3zoc A 2.10 BS02 HBA A 1 Y8 D29 W30 R49 H124 H155 Y12 D33 W34 R53 H128 H159 O58586 YFQGMEGYRLLYPMRTYLIVSGHGEETNVMAADWVTVVSFDPFIVGVAVAPKRTTHKLIKKYGEFVISVPSLDVLRDVWIAGTKKGPSKLKEMSVTLIPSKKVKVPSIEEALANIECRVIDARSYGDHTFFVGEVVGYTYKDYAFEKGKPNLKAKFLAHVSWSEFVTFSEKVHKAE 3zod A 1.68 BS02 HQE A 1 Y8 D29 W30 R49 H124 Y16 D37 W38 R57 H132 O58586 HENLYFQGMEGYRLLYPMRTYLIVSGHGEETNVMAADWVTVVSFDPFIVGVAVAPKRTTHKLIKKYGEFVISVPSLDVLRDVWIAGTKKGPSKLKEMSVTLIPSKKVKVPSIEEALANIECRVIDARSYGDHTFFVGEVVGYTYKDYAFEKGKPNLKAKFLAHVSWSEFVTFSEKVHKAE 3zoe A 1.85 BS01 HBA A 1 Y17 V38 W39 R58 H131 Y162 Y17 V38 W39 R58 H131 Y159 Q72HI0 MRSYRAQGPLPGFYHYYPGVPAVVGVRVEERVNFCPAVWNTGLSADPPLFGVSISPKRFTHGLLLKARRFSASFHPFGQKDLVHWLGSHSGREVDKGQAPHFLGHTGVPILEGAYAAYELELLEVHTFGDHDLFVGRVVAVWEEEGLLDRPKPGLALLYYGKGLYGRPAEETFAP 3zoe A 1.85 BS02 FMN A 1 N33 P36 A37 V38 W39 S53 I54 S55 R58 F59 T60 L86 G87 H89 S90 G91 K96 H131 Y162 Y168 N33 P36 A37 V38 W39 S53 I54 S55 R58 F59 T60 L86 G87 H89 S90 G91 K96 H131 Y159 Y165 Q72HI0 MRSYRAQGPLPGFYHYYPGVPAVVGVRVEERVNFCPAVWNTGLSADPPLFGVSISPKRFTHGLLLKARRFSASFHPFGQKDLVHWLGSHSGREVDKGQAPHFLGHTGVPILEGAYAAYELELLEVHTFGDHDLFVGRVVAVWEEEGLLDRPKPGLALLYYGKGLYGRPAEETFAP 3zof A 2.15 BS01 HQE A 1 Y17 V38 W39 R58 H131 Y17 V38 W39 R58 H131 Q72HI0 MRSYRAQGPLPGFYHYYPGVPAVVGVRVEERVNFCPAVWNTGLSADPPLFGVSISPKRFTHGLLLKARRFSASFHPFGQKDLVHWLGSHSGREVDKGQAPHFLGHTGVPILEGAYAAYELELLEVHTFGDHDLFVGRVVAVWEEEGLLDEKGRPKPGLALLYYGKGLYGRPAEETFAP 3zoh B 1.65 BS01 A2Q B 1 V38 W39 R58 H131 V38 W39 R58 H131 Q72HI0 MRSYRAQGPLPGFYHYYPGVPAVVGVRVEERVNFCPAVWNTGLSADPPLFGVSISPKRFTHGLLLKARRFSASFHPFGQKDLVHWLGSHSGREVDKGQAPHFLGHTGVPILEGAYAAYELELLEVHTFGDHDLFVGRVVAVWEEEGLLDEKGRPKPGLALLYYGKGLYGRPAEETFAP 3zoh C 1.65 BS01 A2Q C 1 W39 R58 H131 W39 R58 H131 Q72HI0 MRSYRAQGPLPGFYHYYPGVPAVVGVRVEERVNFCPAVWNTGLSADPPLFGVSISPKRFTHGLLLKARRFSASFHPFGQKDLVHWLGSHSGREVDKGQAPHFLGHTGVPILEGAYAAYELELLEVHTFGDHDLFVGRVVAVWEEEGLLDEKGRPKPGLALLYYGKGLYGRPAEETFAP 4bkq A 2.30 BS01 NAI A 1 G71 S73 T74 G75 Y76 F96 F97 E98 G133 D134 A135 F136 S161 L162 A163 S164 F246 T247 Y248 K267 L294 K295 A296 V297 T299 A301 S302 G64 S66 T67 G68 Y69 F89 F90 E91 G126 D127 A128 F129 S154 L155 A156 S157 F239 T240 Y241 K260 L287 K288 A289 V290 T292 A294 S295 1.3.1.-,1.3.1.9 Q8Z9U1 HHHSSGLVPRGSHMLEMIIKPRVRGFICVTAHPTGCEANVKKQIDYVTTEGPIANGPKRVLVIGASTGYGLAARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQKGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVIYSLASPRRTHPKTGEVFNSALKPIGNAVNLRGLDTDKEVIKESVLQPATQSEIDSTVAVMGGEDWQMWIDALLDAGVLAEGAQTTAFTYLGEKITHDIYWNGSIGAAKKDLDQKVLAIRESLAAHGGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKEKGTHEGCIEQVYSLYKDSLCGDSPHMDQEGRLRADYKELDPEVQNQVQQLWDQVTNDNIYQLTDFVGYKSEFLNLFGFGIDGVDYDADVNPDVKIPNLIQG 4blj A 1.20 BS01 70B A 1 R144 H158 N160 R162 N174 W181 E184 R186 R32 H46 N48 R50 N62 W69 E72 R74 P17931 MLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI 4bu2 A 2.78 BS01 AKG A 1 Y167 G175 L176 H179 D181 K194 H240 H253 T255 Y103 G111 L112 H115 D117 K130 H176 H189 T191 1.14.11.- Q8IUF8 PSALNFDSPSSLFESLISPIKTETFFKEFWEQKPLLIQRDDPALATYYGSLFKLTDLKSLCRDVNVCRATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTVPLAREYSVEAEERIGRPVHEFMLKPGDLLYFPRGTIHQADTPAGLAHSTHVTISTYQNNSWGDFLLDTISGLVFDTAKEDVELRTGIPRQLLLQVESTTVATRRLSGFLRTLADRLEGTKELLSSDMKKDFIMHRLPPYSAKLPRLDSVVRLQFKDHIVLTVLPDQEKMVYIYHSLKNSRETHMMGNEFHGLRFPLSHLDALKQIWNSPAISVKDLKLTTDEEKESLVLSLWTECLIQVV 4bv1 A 1.90 BS01 FE A 1 H10 H35 H41 C97 H100 H10 H35 H41 C97 H100 Q74MF3 MIKTEYNPKHSPIIEIEKEGELYKITIEVGKEVKHPNEPSHHIQWVDLYFEPEGKEPTHIARIEFKAHGEYNNYTEPKAIVYAKLEGKGKLIAISYCTLHGLWKTEKEL 4bxf A 2.05 BS01 III C 1 N101 Q136 H138 Q139 L161 G163 N165 Y167 H179 D181 D182 V183 C209 T255 S257 T258 Q260 D333 H337 M405 M406 G407 N72 Q107 H109 Q110 L132 G134 N136 Y138 H150 D152 D153 V154 C180 T226 S228 T229 Q231 D304 H308 M369 M370 G371 1.14.11.- Q8IUF8 PSALNFDSPSSLFESLISPIKTETFFKEFWEQKPLLIQRDDPALATYYGSLFKLTDLKSLCSRGMYYGRDVNVCRCVNGKKKVLNKDGKAHFLQLRKDFDQKRATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTVPLARECSVEAEERIGRPVHEFMLKPGDLLYFPRGTIHQADTPAGLAHSTHVTISTYQNNSWGDFLLDTISGLVFDTAKEDVELRTGIPRQLLLQVESTTVATRRLSGFLRTLADRLEGTKELLSSDMKKDFIMHRLPPYSAGDGAELSTPGGKLPRLDSVVRLQFKDHIVLTVLPAQEKMVYIYHSLKNSRETHMMGNEFHGLRFPLSHLDALKQIWNSPAISVKDLKLTTDEEKESLVLSLWTECLIQVV 4bxf A 2.05 BS02 MN A 1 H179 D181 H240 H150 D152 H211 1.14.11.- Q8IUF8 PSALNFDSPSSLFESLISPIKTETFFKEFWEQKPLLIQRDDPALATYYGSLFKLTDLKSLCSRGMYYGRDVNVCRCVNGKKKVLNKDGKAHFLQLRKDFDQKRATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTVPLARECSVEAEERIGRPVHEFMLKPGDLLYFPRGTIHQADTPAGLAHSTHVTISTYQNNSWGDFLLDTISGLVFDTAKEDVELRTGIPRQLLLQVESTTVATRRLSGFLRTLADRLEGTKELLSSDMKKDFIMHRLPPYSAGDGAELSTPGGKLPRLDSVVRLQFKDHIVLTVLPAQEKMVYIYHSLKNSRETHMMGNEFHGLRFPLSHLDALKQIWNSPAISVKDLKLTTDEEKESLVLSLWTECLIQVV 4bxf A 2.05 BS03 AKG A 1 Y167 H179 D181 K194 H240 H253 T255 Y138 H150 D152 K165 H211 H224 T226 1.14.11.- Q8IUF8 PSALNFDSPSSLFESLISPIKTETFFKEFWEQKPLLIQRDDPALATYYGSLFKLTDLKSLCSRGMYYGRDVNVCRCVNGKKKVLNKDGKAHFLQLRKDFDQKRATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTVPLARECSVEAEERIGRPVHEFMLKPGDLLYFPRGTIHQADTPAGLAHSTHVTISTYQNNSWGDFLLDTISGLVFDTAKEDVELRTGIPRQLLLQVESTTVATRRLSGFLRTLADRLEGTKELLSSDMKKDFIMHRLPPYSAGDGAELSTPGGKLPRLDSVVRLQFKDHIVLTVLPAQEKMVYIYHSLKNSRETHMMGNEFHGLRFPLSHLDALKQIWNSPAISVKDLKLTTDEEKESLVLSLWTECLIQVV 4bxf B 2.05 BS01 III D 1 Q136 H138 Q139 L161 G163 N165 Y167 H179 D181 C209 T255 S257 Q260 D333 H337 M405 M406 Q106 H108 Q109 L131 G133 N135 Y137 H149 D151 C179 T225 S227 Q230 D303 H307 M367 M368 1.14.11.- Q8IUF8 SALNFDSPSSLFESLISPIKTETFFKEFWEQKPLLIQRDDPALATYYGSLFKLTDLKSLCSRGMYYGRDVNVCRCVNGKKKVLNKDGKAHFLQLRKDFDQKRATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTVPLARECSVEAEERIGRPVHEFMLKPGDLLYFPRGTIHQADTPAGLAHSTHVTISTYQNNSWGDFLLDTISGLVFDTAKEDVELRTGIPRQLLLQVESTTVATRRLSGFLRTLADRLEGTKELLSSDMKKDFIMHRLPPYSAGDGAELSTPGGKLPRLDSVVRLQFKDHIVLTVLPQEKMVYIYHSLKNSRETHMMTEFHGLRFPLSHLDALKQIWNSPAISVKDLKLTTDEEKESLVLSLWTECLIQVV 4bxf B 2.05 BS03 AKG B 1 H179 D181 K194 W196 H240 H253 T255 H149 D151 K164 W166 H210 H223 T225 1.14.11.- Q8IUF8 SALNFDSPSSLFESLISPIKTETFFKEFWEQKPLLIQRDDPALATYYGSLFKLTDLKSLCSRGMYYGRDVNVCRCVNGKKKVLNKDGKAHFLQLRKDFDQKRATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYITPAGSQGLPPHYDDVEVFILQLEGEKHWRLYHPTVPLARECSVEAEERIGRPVHEFMLKPGDLLYFPRGTIHQADTPAGLAHSTHVTISTYQNNSWGDFLLDTISGLVFDTAKEDVELRTGIPRQLLLQVESTTVATRRLSGFLRTLADRLEGTKELLSSDMKKDFIMHRLPPYSAGDGAELSTPGGKLPRLDSVVRLQFKDHIVLTVLPQEKMVYIYHSLKNSRETHMMTEFHGLRFPLSHLDALKQIWNSPAISVKDLKLTTDEEKESLVLSLWTECLIQVV 4c0n A 1.77 BS01 HEM A 1 I58 F59 A67 N70 F74 F75 Y85 K89 L94 R97 H98 F101 V103 A108 W111 F137 T140 A141 L144 I57 F58 A66 N69 F73 F74 Y84 K88 L93 R96 H97 F100 V102 A107 W110 F136 T139 A140 L143 Q67XG0 QSLQDKASVLSGVDQAEAFAIDESNLFDKLGLQTFINLSTNFYTRVYDDEEEWFQSIFSNSNKEDAIQNQYEFFVQRMGGPPLYSQRKGHPALIGRHRPFPVTHQAAERWLEHMQNALDDSVDIDQDSKIKMMKFFRHTAFFLVAGNELK 4c1p A 2.63 BS01 BXP A 1 E357 Y360 M362 T365 D367 H418 Y434 C442 F443 M446 T515 D517 S518 W654 Q701 S710 Y713 R715 E333 Y336 M338 T341 D343 H394 Y410 C418 F419 M422 T491 D493 S494 W630 Q677 S686 Y689 R691 3.2.1.37 PKNMFFNAHHSPVGAFASFTLGFPGKSGGLDLELGRPPRQNVYIGVASLSQPGMYEVLPFFEAGDDESKRYDIENPDPNPEKPQILVPFPNEMIQREFHVSTDTWKAGDLTFTIYSPVKSVPNPDTAKEEDLKFALVPAVIAELTIDNTKGTSPRRAFFGFEGNDPYTSMRRIDDTCPPLRGVGQGRITAIVSKHSDVRSALHFSLEDILTTPLEENWTFGLGKVGALIMDTPAGMKRTYQFAVCFYRSGYATAGLDTSYFYTRFFKNIEEVGKYALDHIEALKERAFQSNQLIERDWLSDDQKFMMAHAIRSYYGNTQLLEQEGKPIWVVNEGEYRMMNTFDLTVDQLFFELKMNPWTVKNVLDLYVERYSYYDRVRFPGEEKEYPGGISFTHDMGVANTFSRPHYSAYELYGIDGCFSHMTHEQLVNWVLCAAVYIEQTKDWAWRQEKLPILEQCLESMVNRDHPDPEKRNGVMGLDSTRTMGGAEITTYDSLDVSLGQARNNLYLAGKCWAAYVALEKIFRDTGKEALAALAGEQAEKCAATIVSYVTEQGYIPAVMGEGNDSKIIPAIEGLVFPYFTNCHEALDPHGRFGEYIRALRKHLQYVLTEGICLFPDGGWKISSTSNNSWLSKIYLCQFIARRILGWKWDEAGAKADAAHVAWLTHPTLSVWSWSDQIIAGEISGSKYYPRGVTSILWLEEGK 4c6h A 1.61 BS01 HE2 A 1 D106 I132 F142 A146 F150 V210 L247 D105 I131 F141 A145 F149 V209 L246 3.8.1.5 24613925 TTSFRDKKKFATVHGKQMAYIEEGTGDPIVFLHGNPMSSYLWRNIMPHLAGKGRLIAPDLIGMGDSDKLDNSGPDSYTFAEHCTYLFALLEQLGVTENVTLVIHDWGSGLGFHWAHTHSDAVKGIAFMEAIVETRESWDAFPERAREMFQALRSPAGEEMVLEKNLFVEALVPGSILRDLTEEEMNEYRRPFANAGEDRRPTLTFPRQVPIEGQPKDVTELVDAYVDWLGQTSIPKLFINADPGVLITGEVRDRVRSWPNLTEVTVAGLHFIQEDSPDEIGAAVRDWHASL 4c8r A 2.82 BS02 6YT A 1 L199 H202 D204 L217 S229 F340 H347 G348 R349 R360 L199 H202 D204 L217 S229 F340 H347 G348 R349 R360 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4c8r C 2.82 BS02 6YT C 1 W181 L199 H202 L217 H347 R349 R360 W181 L199 H202 L217 H347 R349 R360 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4c8r D 2.82 BS02 6YT D 1 Y177 W181 L199 H202 D204 L217 H347 R360 Y177 W181 L199 H202 D204 L217 H347 R360 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4c8r E 2.82 BS02 6YT E 1 W181 V183 L199 H202 D204 H347 R349 R360 W181 V183 L199 H202 D204 H347 R349 R360 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4c8r F 2.82 BS02 6YT F 1 L199 H202 L217 S229 F340 H347 R349 R360 L199 H202 L217 S229 F340 H347 R349 R360 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4cck A 2.15 BS02 OGA A 1 Y328 F337 H340 K355 W357 H405 H417 T419 Y147 F156 H159 K174 W176 H224 H236 T238 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLA 4cck B 2.15 BS02 OGA B 1 Y328 F337 H340 D342 K355 H405 H417 T419 Y147 F156 H159 D161 K174 H224 H236 T238 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLA 4cck C 2.15 BS02 OGA C 1 Y328 H340 K355 H405 H417 T419 Y147 H159 K174 H224 H236 T238 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLAL 4ccm A 2.51 BS01 III C 1 Q260 R272 R297 L299 C300 M322 G324 N326 Y328 F337 H340 I344 N376 T419 S421 T422 Q424 V576 Y577 Q79 R91 R116 L118 C119 M141 G143 N145 Y147 F156 H159 I163 N195 T238 S240 T241 Q243 V394 Y395 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRVPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLA 4ccm B 2.51 BS01 III D 1 Q260 R272 T274 R297 L299 C300 M322 G324 N326 Y328 F337 H340 D342 I344 N376 T419 S421 Q424 Y577 Q79 R91 T93 R116 L118 C119 M141 G143 N145 Y147 F156 H159 D161 I163 N195 T238 S240 Q243 Y396 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRVPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLAL 4ccm B 2.51 BS03 OGA B 1 Y328 F337 H340 K355 H405 H417 T419 Y147 F156 H159 K174 H224 H236 T238 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRVPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLAL 4ccn A 2.23 BS01 III C 1 G259 R272 T274 R297 C299 S300 M322 G324 N326 Y328 F337 H340 D342 I344 N376 T419 S421 T422 Q424 Y577 G78 R91 T93 R116 C118 S119 M141 G143 N145 Y147 F156 H159 D161 I163 N195 T238 S240 T241 Q243 Y395 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLCSPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLAL 4ccn B 2.23 BS01 III D 1 Q260 R272 T274 R297 C299 S300 M322 G324 N326 Y328 H340 D342 N376 T419 S421 Q424 Q79 R91 T93 R116 C118 S119 M141 G143 N145 Y147 H159 D161 N195 T238 S240 Q243 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLCSPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLAL 4ccn B 2.23 BS03 OGA B 1 Y328 F337 H340 D342 K355 W357 H405 A407 H417 T419 Y147 F156 H159 D161 K174 W176 H224 A226 H236 T238 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLCSPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLAL 4cco A 2.30 BS01 III C 1 G259 Q260 R297 L299 C300 M322 G324 N326 Y328 H340 D342 I344 C373 S374 P375 N376 T419 S421 T422 Q424 V576 Y577 G78 Q79 R116 L118 C119 M141 G143 N145 Y147 H159 D161 I163 C192 S193 P194 N195 T238 S240 T241 Q243 V394 Y395 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTCSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLAL 4cco B 2.30 BS01 III D 1 Q260 R297 L299 C300 M322 G324 N326 Y328 F337 H340 D342 C373 S374 T419 S421 Q424 V576 Y577 Q79 R116 L118 C119 M141 G143 N145 Y147 F156 H159 D161 C192 S193 T238 S240 Q243 V395 Y396 1.14.11.-,1.14.11.27 Q9H6W3 MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTCSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLAL 4cgu A 2.11 BS01 III C 1 K8 N12 F15 V39 N43 K50 I76 K79 Y82 R83 K9 N13 F16 V40 N44 K51 I77 K80 Y83 R84 P25638 24794838 LMSQFEKQKEQGNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQMCQQGLRYTSTAEHVAIRSKLQYRLELAQGAVGSVQIPVVEVDELPEGYDRS 4cgv B 2.54 BS01 III F 1 K137 N141 F144 Y156 V168 N172 S175 Y200 K202 R206 K10 N14 F17 Y29 V41 N45 S48 Y73 K75 R79 Q9H6T3 24794838 VDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKEN 4cgv C 2.54 BS01 III E 1 K137 N141 F144 V168 N172 S175 R179 Y200 K202 R206 K13 N17 F20 V44 N48 S51 R55 Y76 K78 R82 Q9H6T3 24794838 GIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALAS 4cgw A 3.00 BS01 III C 1 K286 N290 F293 N321 M324 K328 Y349 K351 A354 R355 K20 N24 F27 N55 M58 K62 Y83 K85 A88 R89 Q9H6T3 24794838 EGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEP 4cgw B 3.00 BS01 III D 1 K286 N290 F293 L317 N321 Y349 R355 K14 N18 F21 L45 N49 Y77 R83 Q9H6T3 24794838 IEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLE 4ci7 A 1.40 BS01 CA A 1 L339 E448 K460 N487 L298 E407 K419 N446 3.4.22.15 C9YQ11 GSHKTLDGVETAEYSESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRKSSVAYNPMDLGLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNKDKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDKKMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGVPQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETDIDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTS 4ciu A 3.50 BS01 ADP A 1 P179 V180 I181 R183 P208 G209 V210 G211 K212 T213 A214 I349 P387 D388 I391 P21 V22 I23 R25 P50 G51 V52 G53 K54 T55 A56 I169 P207 D208 I211 P63284 QALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGEFEERLKGVLNDLAKQEGNVILFIDALHTMVGDAGNMLKPALARGELHCVGATTLDEYRQYIFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQELHHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDEAMVRIDMSEFMEKHSVSRLVGAGGYLTEAVRRRPYSVILLDAVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFLDYAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDEALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAVQH 4ciu A 3.50 BS02 ADP A 2 R569 V570 I571 T607 G608 V609 G610 K611 T612 E613 I774 Q778 A814 R815 R379 V380 I381 T417 G418 V419 G420 K421 T422 E423 I573 Q577 A613 R614 P63284 QALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGEFEERLKGVLNDLAKQEGNVILFIDALHTMVGDAGNMLKPALARGELHCVGATTLDEYRQYIFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQELHHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDEAMVRIDMSEFMEKHSVSRLVGAGGYLTEAVRRRPYSVILLDAVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFLDYAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDEALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAVQH 4ckt A 3.00 BS01 III C 1 K57 K64 F66 L110 D111 A112 K113 L165 K166 Y167 R168 K11 K18 F20 L64 D65 A66 K67 L119 K120 Y121 R122 Q9CQJ2 24794838 QIQPKPGFCVKTNSSEGKVFINICHSPSIPPPADVTEDELLQMLEEDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSNFYLRMQNSDFLRELVVTIAREGLEDKYGLQLNPEWRMLKYRSFLGS 4ckt B 3.00 BS01 III D 1 K64 F66 A112 K113 L165 K166 Y167 R168 K17 F19 A65 K66 L118 K119 Y120 R121 Q9CQJ2 24794838 IQPKPGFCVKTNSSEGKVFINICHSPSIPPPADVTEDELLQMLEEDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSNFYLRMQNSDFLRELVVTIAREGLEDKYGLQLNPEWRMLKYRSFLGSISQQNI 4cpm A 2.75 BS02 G39 A 1 R115 E116 D148 R149 W176 I220 R222 A244 E274 R291 N293 R373 Y408 R40 E41 D73 R74 W101 I145 R147 A169 E199 R216 N218 R298 Y333 3.2.1.18 C0LT34 24795482 EPEWTYPRLSCPGSTFQKALLISPHRFGETKGNSAPLIIREPFIACGPNECKHFALTHYAAQPGGYYNGTRGDRNKLRHLISVKLGKIPTVENSIFHMAAWSGSACHDGKEWTYIGVDGPDNNALLKVKYGEAYTDTYHSYANKILRTQESACNCIGGNCYLMITDGSASGVSECRFLKIREGRIIKEIFPTGRVKHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTDTYLDTPRPNDGSITGPCESNGDKGSGGIKGGFVHQRMESKIGRWYSRTMSKTERMGMGLYVKYDGDPWADSDALAFSGVMVSMKEPGWYSFGFEIKDKKCDVPCIGIEMVHDGGKETWHSAATAIYCLMGSGQLLWDTVTGVDMAL 4cpy A 1.80 BS02 G39 A 1 R115 E116 D148 R149 W176 L220 A244 E274 R291 N293 R373 Y408 R40 E41 D73 R74 W101 L145 A169 E199 R216 N218 R298 Y333 3.2.1.18 H6QN19 24795482 EPEWTYPRLSCPGSTFQKALLISPHRFGETKGNSAPLIIREPFIACGPNECKHFALTHYAAQPGGYYNGTRGDRNKLRHLISVKLGKIPTVENSIFHMAAWSGSACHDGKEWTYIGVDGPDNDALLKVKYGEAYTDTYHSYANKLLRTQESACNCIGGNCYLMITDGSASGVSECRFLKIREGRIIKEIFPTGRVKHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTDTYLDTPRPDDGSITGPCESNGDKGSGGIKGGFVHQRMESKIGRWYSRTMSKTERMGMGLYVKYDGDPWADSDALAFSGVMVSMKEPGWYSFGFEIKDKECDVPCIGIEMVHDGGKETWHSAATAIYCLMGSGQLLWDTVTGVDMAL 4cpz A 2.20 BS02 ZMR A 1 R115 E116 D148 R149 R153 W176 L220 E225 E274 E275 R291 N293 R373 Y408 R40 E41 D73 R74 R78 W101 L145 E150 E199 E200 R216 N218 R298 Y333 3.2.1.18 H6QN19 24795482 EPEWTYPRLSCPGSTFQKALLISPHRFGETKGNSAPLIIREPFIACGPNECKHFALTHYAAQPGGYYNGTRGDRNKLRHLISVKLGKIPTVENSIFHMAAWSGSACHDGKEWTYIGVDGPDNDALLKVKYGEAYTDTYHSYANKLLRTQESACNCIGGNCYLMITDGSASGVSECRFLKIREGRIIKEIFPTGRVKHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTDTYLDTPRPDDGSITGPCESNGDKGSGGIKGGFVHQRMESKIGRWYSRTMSKTERMGMGLYVKYDGDPWADSDALAFSGVMVSMKEPGWYSFGFEIKDKECDVPCIGIEMVHDGGKETWHSAATAIYCLMGSGQLLWDTVTGVDMAL 4cpz B 2.20 BS02 ZMR B 1 R115 E116 D148 R149 R153 W176 E225 A244 E274 R291 R373 Y408 R40 E41 D73 R74 R78 W101 E150 A169 E199 R216 R298 Y333 3.2.1.18 H6QN19 24795482 EPEWTYPRLSCPGSTFQKALLISPHRFGETKGNSAPLIIREPFIACGPNECKHFALTHYAAQPGGYYNGTRGDRNKLRHLISVKLGKIPTVENSIFHMAAWSGSACHDGKEWTYIGVDGPDNDALLKVKYGEAYTDTYHSYANKLLRTQESACNCIGGNCYLMITDGSASGVSECRFLKIREGRIIKEIFPTGRVKHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTDTYLDTPRPDDGSITGPCESNGDKGSGGIKGGFVHQRMESKIGRWYSRTMSKTERMGMGLYVKYDGDPWADSDALAFSGVMVSMKEPGWYSFGFEIKDKECDVPCIGIEMVHDGGKETWHSAATAIYCLMGSGQLLWDTVTGVDMAL 4cpz H 2.20 BS02 ZMR H 1 R115 E116 D148 R149 R153 W176 R222 E225 E274 R291 R373 Y408 R40 E41 D73 R74 R78 W101 R147 E150 E199 R216 R298 Y333 3.2.1.18 H6QN19 24795482 EPEWTYPRLSCPGSTFQKALLISPHRFGETKGNSAPLIIREPFIACGPNECKHFALTHYAAQPGGYYNGTRGDRNKLRHLISVKLGKIPTVENSIFHMAAWSGSACHDGKEWTYIGVDGPDNDALLKVKYGEAYTDTYHSYANKLLRTQESACNCIGGNCYLMITDGSASGVSECRFLKIREGRIIKEIFPTGRVKHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTDTYLDTPRPDDGSITGPCESNGDKGSGGIKGGFVHQRMESKIGRWYSRTMSKTERMGMGLYVKYDGDPWADSDALAFSGVMVSMKEPGWYSFGFEIKDKECDVPCIGIEMVHDGGKETWHSAATAIYCLMGSGQLLWDTVTGVDMAL 4cse A 3.30 BS01 III C 1 K57 K64 L110 D111 A112 K113 K166 Y167 R168 K11 K18 L48 D49 A50 K51 K104 Y105 R106 Q9CQJ2 24794838 QIQPKPGFCVKTNSSEGKVFINICHSPSIPPPADFRIPMSLGEPHAELDAKGQGCTAYDVAVNSNFYLRMQNSDFLRELVVTIAREGLEDKYGLQLNPEWRMLKYRSFLGS 4cse B 3.30 BS01 III D 1 K57 K64 D111 A112 K113 R163 L165 K166 Y167 R168 K9 K16 D48 A49 K50 R100 L102 K103 Y104 R105 Q9CQJ2 24794838 QPKPGFCVKTNSSEGKVFINICHSPSIPPPADGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSNFYLRMQNSDFLRELVVTIAREGLEDKYGLQLNPEWRMLKYRSFLGSIS 4cuf A 2.29 BS02 CA A 2 N490 T491 E493 D507 K508 N79 T80 E82 D96 K97 P46531 DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDASCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQVDLHHI 4cuf A 2.29 BS03 CA A 3 V413 E415 N431 T432 G434 S435 V2 E4 N20 T21 G23 S24 P46531 DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDASCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQVDLHHI 4cuw H 3.70 BS01 III m 1 R91 V93 R91 V93 24792965 MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFITEDL 4cuw H 3.70 BS02 III m 2 Y180 S182 Y180 S182 24792965 MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFITEDL 4cuw H 3.70 BS03 III m 3 I172 R173 L176 Y180 I172 R173 L176 Y180 24792965 MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFITEDL 4cuw H 3.70 BS04 TYR m 1 Q162 V181 Q162 V181 24792965 MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFITEDL 4cuw T 3.70 BS01 III b 1 N77 M79 N82 R83 Y84 N76 M78 N81 R82 Y83 24792965 GKSHGYRSRTRYMFQRDFRKHGAVHLSTYLKVYKVGDIVDIKANGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI 4cuw X 3.70 BS01 III l 1 M88 V114 P116 N117 G118 M67 V93 P95 N96 G97 24792965 KALKVRTSATFRLPKTLKLARAPKYASKAVPHYNRLDSYKVIEQPITSETAMKKVEDGNILVFQVSMKANKYQIKKAVKELYEVDVLKVNTLVRPNGTKKAYVRLTADYDALDIANRIGYI 4cuw Y 3.70 BS01 III l 2 L76 K77 L75 K76 24792965 AKQSLDVSSDRRKARKAYFTAPSSQRRVLLSAPLSKELRAQYGIKALPIRRDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPSKLVITKLHLDKDRKALIQRKGGKLE 4cuw j 3.70 BS01 III l 1 L18 N20 L17 N19 24792965 GKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA 4cuw j 3.70 BS02 III l 3 K14 T17 L18 R25 K13 T16 L17 R24 24792965 GKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA 4cuy D 3.70 BS01 III d 1 G15 Y18 N22 G12 Y15 N19 24792965 LISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHSGQPVNDFIDTATRHVLMRQGVLGIKVKIMRDPAKSRTGPKALPDAVTIIEPKEEEPILAPSVKDY 4cuy J 3.70 BS01 III e 1 G35 K37 H123 G34 K36 H122 24792965 PRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAASVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARK 4cuy J 3.70 BS02 III e 2 L28 G32 E33 K37 H123 L27 G31 E32 K36 H122 24792965 PRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAASVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARK 4cuy K 3.70 BS01 III d 2 N28 W61 Q62 N28 W61 Q62 24792965 MLMPKEDRNKIHQYLFQEGVVVAKADFNQAAHEEIDTKNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQ 4cuy U 3.70 BS01 III d 3 L63 I65 L47 I49 24792965 QQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVVAS 4cuy U 3.70 BS02 III d 4 I65 P71 I49 P55 24792965 QQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVVAS 4cuy U 3.70 BS03 III d 5 K69 Y82 K53 Y66 24792965 QQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVVAS 4cuy U 3.70 BS04 III d 6 Y82 E83 M84 Y66 E67 M68 24792965 QQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVVAS 4cuy U 3.70 BS05 III d 7 E80 T81 Y82 E83 E64 T65 Y66 E67 24792965 QQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVVAS 4cuy X 3.70 BS01 III e 3 K56 I68 K55 I67 24792965 GKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNAGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKP 4cuy X 3.70 BS02 III e 4 A90 G91 W136 A89 G90 W135 24792965 GKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNAGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKP 4cv4 A 1.90 BS01 CO A 1 D93 E148 D47 E102 Q9CQJ2 24794838 QIQPKPGFCVKTNSSEGKVFINICHSPSIPPPADVTEDELLQMLEEDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSNFYLRMQNSDFLRELVVTIAREGLEDKYGLQLNPEWRMLKYRSFLGSISQQNI 4cy1 A 1.50 BS01 III D 1 K46 A47 S49 A65 K67 K87 L88 G89 I90 S91 D107 Y131 F133 Y191 L234 E258 K259 Y260 C261 F263 K16 A17 S19 A35 K37 K57 L58 G59 I60 S61 D77 Y101 F103 Y161 L203 E227 K228 Y229 C230 F232 P61964 24788516 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4cy2 A 2.00 BS01 III C 1 S223 P224 N225 Y228 L240 L249 K250 V268 Q289 S193 P194 N195 Y198 L210 L219 K220 V238 Q259 P61964 24788516 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4cy2 A 2.00 BS02 III D 1 K46 A47 S49 A65 K67 K87 L88 G89 I90 S91 D107 Y131 F133 K259 Y260 C261 F263 L321 K16 A17 S19 A35 K37 K57 L58 G59 I60 S61 D77 Y101 F103 K229 Y230 C231 F233 L291 P61964 24788516 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4cy3 A 1.40 BS01 III D 1 S76 A92 G116 I117 S118 D134 Y158 F160 F176 Y218 K286 Y287 C288 F290 L332 E349 S18 A34 G58 I59 S60 D76 Y100 F102 F118 Y160 K228 Y229 C230 F232 L274 E291 Q9V3J8 24788516 KPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSDT 4cy5 A 2.30 BS01 III C 1 R208 S250 P251 N252 Y255 L276 K277 F293 Q316 R151 S192 P193 N194 Y197 L218 K219 F235 Q258 Q9V3J8 24788516 VKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSDT 4cy5 A 2.30 BS02 III D 1 S76 A92 G116 I117 S118 D134 Y158 F160 F176 L261 K286 Y287 C288 F290 L332 S19 A35 G59 I60 S61 D77 Y101 F103 F119 L203 K228 Y229 C230 F232 L274 Q9V3J8 24788516 VKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSDT 4k7l B 1.38 BS01 III A 1 Y25 M29 R33 N34 L35 N44 T45 F46 V47 H48 E49 S50 L51 V54 V116 P117 V118 H119 F120 Y3 M7 R11 N12 L13 N22 T23 F24 V25 H26 E27 S28 L29 V32 V94 P95 V96 H97 F98 P61823 SNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 4ki7 C 2.80 BS01 1R2 C 1 N12 L16 Y24 N75 G77 H81 H101 I102 V105 R112 N10 L14 Y22 N73 G75 H79 H99 I100 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4ki7 D 2.80 BS01 1R2 D 1 N12 L13 R15 L16 R19 Y24 N75 G77 H81 H101 I102 S103 R112 N10 L11 R13 L14 R17 Y22 N73 G75 H79 H99 I100 S101 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHVG 4ki7 E 2.80 BS01 1R2 E 1 P11 N12 L13 L16 E20 Y24 N75 G77 G78 H81 H101 I102 S103 R112 P9 N10 L11 L14 E18 Y22 N73 G75 G76 H79 H99 I100 S101 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4ki7 N 2.80 BS01 1R2 N 1 L13 R15 L16 E20 Y24 N75 G77 H81 H101 I102 S103 V105 R112 L11 R13 L14 E18 Y22 N73 G75 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4ki7 T 2.80 BS01 1R2 T 1 N12 L13 L16 Y24 N75 G77 G78 H81 H101 I102 S103 V105 R112 N10 L11 L14 Y22 N73 G75 G76 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiu A 2.40 BS01 KIU A 1 P11 N12 L13 R15 L16 E20 Y24 N75 G77 G78 H81 H101 I102 S103 V105 R112 P9 N10 L11 R13 L14 E18 Y22 N73 G75 G76 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiu B 2.40 BS01 KIU B 1 P11 N12 R15 R19 E20 Y24 N75 G77 G78 H81 H101 I102 S103 V105 R112 P9 N10 R13 R17 E18 Y22 N73 G75 G76 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiu C 2.40 BS01 KIU C 1 P11 N12 L13 L16 E20 Y24 N75 G77 H81 H101 I102 S103 V105 R108 R112 P9 N10 L11 L14 E18 Y22 N73 G75 H79 H99 I100 S101 V103 R106 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiu D 2.40 BS01 KIU D 1 P11 N12 L13 R15 L16 R19 Y24 N75 G77 H81 H101 I102 S103 R108 R112 P9 N10 L11 R13 L14 R17 Y22 N73 G75 H79 H99 I100 S101 R106 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHVG 4kiu G 2.40 BS01 KIU G 1 N12 L13 R15 R19 Y24 N75 G77 G78 H81 H101 I102 S103 V105 R112 N10 L11 R13 R17 Y22 N73 G75 G76 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiu H 2.40 BS01 KIU H 1 N12 L13 L16 R19 E20 Y24 N75 G77 H81 H101 I102 S103 V105 R112 N10 L11 L14 R17 E18 Y22 N73 G75 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiu I 2.40 BS02 KIU J 1 V84 D88 E92 V82 D86 E90 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiu O 2.40 BS01 KIU O 1 P11 N12 R15 L16 E20 Y24 N75 G77 H81 H101 I102 S103 V105 R112 P9 N10 R13 L14 E18 Y22 N73 G75 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiu X 2.40 BS01 KIU X 1 P11 N12 L13 L16 R19 Y24 N75 G77 G78 H81 H101 I102 S103 V105 R112 P18 N19 L20 L23 R26 Y28 N79 G81 G82 H85 H105 I106 S107 V109 R116 P9WPX7 LYFQSHMSELIVNVINGPNLGRLGRREYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiw C 2.57 BS01 KIW C 1 N12 L13 R15 L16 N75 G77 G78 H81 H101 I102 S103 V105 R112 N10 L11 R13 L14 N70 G72 G73 H76 H96 I97 S98 V100 R107 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiw G 2.57 BS02 KIW G 1 P11 N12 L13 R15 L16 R18 R19 Y24 N75 G77 G78 H81 H101 I102 S103 V105 R112 P9 N10 L11 R13 L14 R16 R17 Y22 N73 G75 G76 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiw J 2.57 BS01 KIW J 1 P11 N12 L13 R15 L16 Y24 N75 G77 H81 H101 I102 S103 V105 R112 P9 N10 L11 R13 L14 Y22 N73 G75 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiw L 2.57 BS01 KIW L 1 N12 R15 L16 R19 Y24 N75 G77 H81 H101 I102 S103 V105 R112 N10 R13 L14 R17 Y19 N70 G72 H76 H96 I97 S98 V100 R107 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiw M 2.57 BS01 KIW M 1 N12 R15 L16 Y24 G77 G78 H81 H101 I102 S103 V105 R112 N10 R13 L14 Y22 G75 G76 H79 H99 I100 S101 V103 R110 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiw R 2.57 BS01 KIW R 1 P11 N12 R15 L16 Y24 N75 G77 G78 H81 H101 I102 S103 R112 P9 N10 R13 L14 Y19 N70 G72 G73 H76 H96 I97 S98 R107 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiw T 2.57 BS01 KIW T 1 R19 E20 V23 N75 G77 G78 H81 H101 I102 S103 V105 R112 R17 E18 V21 N72 G74 G75 H78 H98 I99 S100 V102 R109 4.2.1.10 P9WPX7 LIVNVINGPNLGRLGRREPAVGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kiw X 2.57 BS02 KIW X 1 P11 N12 R15 L16 R18 N75 G77 G78 H81 H101 I102 S103 V105 R112 P9 N10 R13 L14 R16 N70 G72 G73 H76 H96 I97 S98 V100 R107 P9WPX7 LIVNVINGPNLGRLGRREYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4kkf A 1.70 BS01 CBK A 1 H31 E39 E50 W403 W409 D485 R609 W611 H33 E41 E52 W405 W411 D487 R611 W613 3.2.1.91 O65986 VPNNEYVQHFKDMYAKIHNANNGYFSDEGIPYHAVETLMVEAPDYGHETTSEAFSYYMWLEAMNAKLTGDFSGFKKAWDVTEKYIIPGETDQPSASMSNYDPNKPATYAAEHPDPSMYPSQLQFGAAVGKDPLYNELKSTYGTSQVYGMHWLLDVDNWYGFGGATSTSPVYINTFQRGVQESCWETVPQPCKDEMKYGGRNGFLDLFTGDSQYATQFKYTNAPDADARAVQATYYAQLAAKEWGVDISSYVAKSTKMGDFLRYSFFDKYFRKVGNSTQAGTGYDSAQYLLNWYYAWGGGISSNWSWRIGSSHNHFGYQNPMAAWILSNTSDFKPKSPNAATDWNNSLKRQIEFYQWLQSAEGGIAGGASNSNGGSYQAWPAGTRTFYGMGYTPHPVYEDPGSNEWFGMQAWSMQRVAEYYYSSKDPAAKSLLDKWAKWACANVQFDDAAKKFKIPAKLVWTGQPDTWTGSYTGNSNLHVKVEAYGEDLGVAGSLSNALSYYAKALESSTDAADKVAYNTAKETSRKILDYLWASYQDDKGIAVTETRNDFKRFNQSVYIPSGWTGKMPNGDVIQSGATFLSIRSKYKQDPSWPNVEAALANGTGVDMTYHRFWGQSDIAIAFGTYGTLFT 4kkf A 1.70 BS02 CBI A 1 W149 N171 F173 Q174 K216 T218 N219 W290 Y291 Y315 Y395 W151 N173 F175 Q176 K218 T220 N221 W292 Y293 Y317 Y397 3.2.1.91 O65986 VPNNEYVQHFKDMYAKIHNANNGYFSDEGIPYHAVETLMVEAPDYGHETTSEAFSYYMWLEAMNAKLTGDFSGFKKAWDVTEKYIIPGETDQPSASMSNYDPNKPATYAAEHPDPSMYPSQLQFGAAVGKDPLYNELKSTYGTSQVYGMHWLLDVDNWYGFGGATSTSPVYINTFQRGVQESCWETVPQPCKDEMKYGGRNGFLDLFTGDSQYATQFKYTNAPDADARAVQATYYAQLAAKEWGVDISSYVAKSTKMGDFLRYSFFDKYFRKVGNSTQAGTGYDSAQYLLNWYYAWGGGISSNWSWRIGSSHNHFGYQNPMAAWILSNTSDFKPKSPNAATDWNNSLKRQIEFYQWLQSAEGGIAGGASNSNGGSYQAWPAGTRTFYGMGYTPHPVYEDPGSNEWFGMQAWSMQRVAEYYYSSKDPAAKSLLDKWAKWACANVQFDDAAKKFKIPAKLVWTGQPDTWTGSYTGNSNLHVKVEAYGEDLGVAGSLSNALSYYAKALESSTDAADKVAYNTAKETSRKILDYLWASYQDDKGIAVTETRNDFKRFNQSVYIPSGWTGKMPNGDVIQSGATFLSIRSKYKQDPSWPNVEAALANGTGVDMTYHRFWGQSDIAIAFGTYGTLFT 4kmm A 2.60 BS01 HEM A 1 H76 F88 L92 R115 I119 Y123 Y191 S197 T198 H263 L265 V305 H341 I342 E343 H12 F24 L28 R51 I55 Y59 Y127 S133 T134 H199 L201 V241 H277 I278 E279 4.99.1.1 P22830 RKPKTGILMLNHGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4kmm B 2.60 BS01 HEM B 1 H76 F88 L92 L98 R115 I119 Y123 S197 T198 H263 L265 P266 V269 F337 H341 I342 E343 H12 F24 L28 L34 R51 I55 Y59 S133 T134 H199 L201 P202 V205 F273 H277 I278 E279 4.99.1.1 P22830 RKPKTGILMLNHGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL 4kmn A 1.52 BS01 ZN A 1 C300 C303 H320 C327 C50 C53 H70 C77 6.3.2.- Q13490 AAASISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEAA 4kmn A 1.52 BS02 436 A 1 R294 K299 G306 L307 R308 C309 W310 E311 D314 E319 W323 R44 K49 G56 L57 R58 C59 W60 E61 D64 E69 W73 6.3.2.- Q13490 AAASISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEAA 4kmp A 1.95 BS01 ZN A 1 C300 C303 H320 C327 C50 C53 H70 C77 6.3.2.- P98170 ADSHMLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSL 4knq A 1.82 BS01 NUC B 1 P15 W17 W20 Q31 L35 K38 Y51 Q85 I86 G87 R93 G96 S102 G103 G104 P13 W15 W18 Q26 L30 K33 Y46 Q80 I81 G82 R88 G91 S97 G98 G99 P69517 HMTSPFKLPDESPSWTEWRLHNDETQDNPLGFKESWGFGKVVFKRYLRYDRTEASLHRVLGSWTGDSVNYAASRFFGFDQIGCTYSIRFRGVSITVSGGSRTLQHLCEMAIRSKQELLQLAP 4kpl A 2.00 BS01 CS2 A 1 N39 H124 R149 D213 H215 E239 E265 R286 H315 P317 D319 E342 L392 W405 N38 H123 R148 D192 H194 E218 E244 R265 H294 P296 D298 E321 L371 W384 4.2.1.8 Q1QT89 SLKIRDAYTIVTCPGRNFVTLKIVTESGTHGIGDATLNGREMAVAAYLDEHVVPALIGRDAGRIEDTWQYLYRGAYWRRGPVTMTAIAAVDMALWDIKAKAAGMPLYQLLGGKSRERVMTYAHCTGQTIEDCLGEVARHVELGYRAVRVQSGVPGSLPAEHVWSTEKYLNHAPKLFAAVRERFGDDLHVLHDVHHRLTPIEAARLGKAVEPYHLFWLEDCVPAENQESLRLIREHTTTPLAIGEVFNSIHDCRELIQNQWIDYIRMPLTHGGGITAMRRVADLASLYHVRTGFHGPTDLSPVCLGAAIHFDTWVPNFGIQEHMPHTDETDAVFPHDYRFEDGHFLAGESPGHGVDIDEELAAKYPYERASLPVNRLEDGTLWHW 4kpl C 2.00 BS01 KDG C 1 N39 H124 D213 H215 E239 E265 R286 H315 P317 D319 E342 W405 N38 H123 D193 H195 E219 E245 R266 H295 P297 D299 E322 W385 4.2.1.8 Q1QT89 SLKIRDAYTIVTCPGRNFVTLKIVTESGTHGIGDATLNGREMAVAAYLDEHVVPALIGRDAGRIEDTWQYLYRGAYWRRGPVTMTAIAAVDMALWDIKAKAAGMPLYQLLGGKSRERVMTYAHCTGQTIEDCLGEVARHVELGYRAVRVQSGVPGSSLPAEHVWSTEKYLNHAPKLFAAVRERFGDDLHVLHDVHHRLTPIEAARLGKAVEPYHLFWLEDCVPAENQESLRLIREHTTTPLAIGEVFNSIHDCRELIQNQWIDYIRMPLTHGGGITAMRRVADLASLYHVRTGFHGPTDLSPVCLGAAIHFDTWVPNFGIQEHMPHTDETDAVFPHDYRFEDGHFLAGESPGHGVDIDEELAAKYPYERASLPVNRLEDGTLWHW 4kpr E 2.40 BS01 FAD E 1 I18 G19 G21 S22 G23 L41 D42 F43 G57 T58 C59 G63 C64 K67 A130 Y131 G132 A160 T161 G162 Y200 V201 R293 I300 G333 D334 E341 L342 T343 P344 I9 G10 G12 S13 G14 L32 D33 F34 G48 T49 C50 G54 C55 K58 A121 Y122 G123 A151 T152 G153 Y191 V192 R284 I291 G324 D325 E332 L333 T334 P335 1.8.1.9 O89049 SYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKVVYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDIL 4kq0 A 2.10 BS01 NUC B 1 W17 K45 S91 R93 S98 W14 K40 S86 R88 S93 P69517 MTSPFKLPDESPSWTEWRLHNDETNQDNPLGFKESWGFGKVVFKRYLRYDRTEASLHRVLGSWTGDSVNYAASRFFGFDQIGCTYSIRFRGVSITVSGGSRTLQHLCEMAIRSKQEMLQMAP 4l2e A 1.90 BS01 L2E A 1 R266 D291 A292 I327 D328 F347 Y485 R555 Y587 R615 Y655 R24 D49 A50 I85 D86 F105 Y243 R313 Y345 R373 Y413 3.2.1.18 Q0TT67 VEGAVKTEPVDLFHPGFLNSSNYRIPALFKTKEGTLIASIDARRQGGADAPNNDIDTAVRRSEDGGKTWDEGQIIMDYPDKSSVIDTTLIQDDETGRIFLLVTHFPSKYGFWNAGLGSGFKNIDGKEYLCLYDSSGKEFTVRENVVYDKDGNKTEYTTNALGDLFRNGTKIDNINSSTAPLKAKGTSYINLVYSDDDGKTWSEPQNINFQVKKDWMKFLGIAPGRGIQIKNGEHKGRIVVPVYYTNEKGKQSSAVIYSDDSGKNWTIGESPNDNRKLENGKIINSKTLSDDAPQLTECQVVEMPNGQLKLFMRNLSGYLNIATSFDGGATWDETVEKDTNVLEPYCQLSVINYSQKIDGKDAVIFSNPNARSRSNGTVRIGLINQVGTYENGEPKYEFDWKYNKLVKPGYYAYSCLTELSNGNIGLLYEGTPSEEMSYIEMNLKYLESG 4l2e A 1.90 BS03 CA A 2 E511 D515 N516 W573 E269 D273 N274 W331 3.2.1.18 Q0TT67 VEGAVKTEPVDLFHPGFLNSSNYRIPALFKTKEGTLIASIDARRQGGADAPNNDIDTAVRRSEDGGKTWDEGQIIMDYPDKSSVIDTTLIQDDETGRIFLLVTHFPSKYGFWNAGLGSGFKNIDGKEYLCLYDSSGKEFTVRENVVYDKDGNKTEYTTNALGDLFRNGTKIDNINSSTAPLKAKGTSYINLVYSDDDGKTWSEPQNINFQVKKDWMKFLGIAPGRGIQIKNGEHKGRIVVPVYYTNEKGKQSSAVIYSDDSGKNWTIGESPNDNRKLENGKIINSKTLSDDAPQLTECQVVEMPNGQLKLFMRNLSGYLNIATSFDGGATWDETVEKDTNVLEPYCQLSVINYSQKIDGKDAVIFSNPNARSRSNGTVRIGLINQVGTYENGEPKYEFDWKYNKLVKPGYYAYSCLTELSNGNIGLLYEGTPSEEMSYIEMNLKYLESG 4l8f D 1.97 BS01 MTX D 1 F20 G71 G72 G73 A108 L109 E112 S168 H169 Q170 W171 H218 F16 G67 G68 G69 A104 L105 E108 S164 H165 Q166 W167 H214 3.4.19.9 Q6NY42 24028568 KTNERPIIGVLAQDVFDPKPDRNSYIAASYVKFLESAGARVVPVMINKSEDEYSRLFKSINGVLFPGGGVSLESSGYSKAAGIFYRLALEANSNGDYFPVWGTALGFELLTLLTSGELLLSHTNTSGIALPLDFTEDVKGSRLFKEFPEELMKSLATEPLTENSHQWSITTENFTANKKLKKFYRVLSTNTDGYNKFVSTMEAYDFPIYATQWHPEKNAFEWTRPYIPHTPSAIKTTFYMANFFVNEARKNLHSFASTEEEEKALIYNYKPEYTGIQSAFEQTYFFN 4l8w I 2.39 BS01 MTX I 1 F20 G71 G72 G73 C108 L109 E112 S168 H169 Q170 W171 F16 G67 G68 G69 C104 L105 E108 S164 H165 Q166 W167 3.4.19.9 Q6NY42 24028568 KTNERPIIGVLAQDVFDPKPDRNSYIAASYVKFLESAGARVVPVMINKSEDEYSRLFKSINGVLFPGGGVSLESSGYSKAAGIFYRLALEANSNGDYFPVWGTCLGFELLTLLTSGELLLSHTNTSGIALPLDFTEDVKGSRLFKEFPEELMKSLATEPLTENSHQWSITTENFTANKKLKKFYRVLSTNTDGYNKFVSTMEAYDFPIYATQWNPEKNAFEWTRPYIPHTPSAIKTTFYMANFFVNEARKNLHSFASTEEEEKALIYNYKPEYTGIQSAFEQTYFFN 4l8w I 2.39 BS02 DGL I 1 G72 S168 K221 G68 S164 K217 3.4.19.9 Q6NY42 24028568 KTNERPIIGVLAQDVFDPKPDRNSYIAASYVKFLESAGARVVPVMINKSEDEYSRLFKSINGVLFPGGGVSLESSGYSKAAGIFYRLALEANSNGDYFPVWGTCLGFELLTLLTSGELLLSHTNTSGIALPLDFTEDVKGSRLFKEFPEELMKSLATEPLTENSHQWSITTENFTANKKLKKFYRVLSTNTDGYNKFVSTMEAYDFPIYATQWNPEKNAFEWTRPYIPHTPSAIKTTFYMANFFVNEARKNLHSFASTEEEEKALIYNYKPEYTGIQSAFEQTYFFN 4l8w I 2.39 BS03 DGL I 2 S282 A283 F284 S278 A279 F280 3.4.19.9 Q6NY42 24028568 KTNERPIIGVLAQDVFDPKPDRNSYIAASYVKFLESAGARVVPVMINKSEDEYSRLFKSINGVLFPGGGVSLESSGYSKAAGIFYRLALEANSNGDYFPVWGTCLGFELLTLLTSGELLLSHTNTSGIALPLDFTEDVKGSRLFKEFPEELMKSLATEPLTENSHQWSITTENFTANKKLKKFYRVLSTNTDGYNKFVSTMEAYDFPIYATQWNPEKNAFEWTRPYIPHTPSAIKTTFYMANFFVNEARKNLHSFASTEEEEKALIYNYKPEYTGIQSAFEQTYFFN 4l8w G 2.39 BS03 DGL G 2 Y29 S282 A283 F284 Y25 S278 A279 F280 3.4.19.9 Q6NY42 24028568 KTNERPIIGVLAQDVFDPKPDRNSYIAASYVKFLESAGARVVPVMINKSEDEYSRLFKSINGVLFPGGGVSLESSGYSKAAGIFYRLALEANSNGDYFPVWGTCLGFELLTLLTSGELLLSHTNTSGIALPLDFTEDVKGSRLFKEFPEELMKSLATEPLTENSHQWSITTENFTANKKLKKFYRVLSTNTDGYNKFVSTMEAYDFPIYATQWNPEKNAFEWTRPYIPHTPSAIKTTFYMANFFVNEARKNLHSFASTEEEEKALIYNYKPEYTGIQSAFEQTYFFN 4leb A 1.40 BS01 III B 1 Y21 G27 K59 S170 R171 V172 R294 W295 T296 G297 Y22 G28 K60 S171 R172 V173 R295 W296 T297 G298 O74623 GKTITGVFNSFNSLTWSNAATYNYKGPGTPTWNAVLGWSLDGTSASPGDTFTLNMPCVFKFTTSQTSVDLTAHGVKYATCQFQAGEEFMTFSTLTCTVSNTLTPSIKALGTVTLPLAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGGKKISINVDFERSNVDPKGYLTDSRVIPSLNKVSTLFVAPQCANGYTSGTMGFANTYGDVQIDCSNIHVGITKGLNDWNYPVSSESFSYTKTCSSNGIFITYKNVPAGYRPFVDAYISATDVNSYTLSYANEYTCAGGYWQRAPFTLRWTGY 4lem A 2.27 BS01 B12 A 1 I186 F246 D250 F263 A268 T269 H272 R373 I187 F247 D251 F264 A269 T270 H273 R374 1.5.1.12 O50443 24699642 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMA 4lem B 2.27 BS01 B12 B 1 I186 F246 D250 A268 T269 H272 R373 I187 F247 D251 A269 T270 H273 R374 1.5.1.12 O50443 24699642 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAV 4lem C 2.27 BS01 B12 C 1 I186 F246 D250 T269 H272 I187 F247 D251 T270 H273 1.5.1.12 O50443 24699642 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAVD 4lem C 2.27 BS02 MG C 1 A385 K386 A388 V391 A386 K387 A389 V392 1.5.1.12 O50443 24699642 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAVD 4lem D 2.27 BS01 B12 D 1 I186 F246 D250 F263 A268 T269 H272 I187 F247 D251 F264 A269 T270 H273 1.5.1.12 O50443 24699642 HMDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHMAVD 4lit A 2.40 BS02 AKG A 1 L116 M146 S148 H159 D161 R174 H221 L81 M111 S113 H124 D126 R139 H175 1.14.11.- P27431 EYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLLQVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSRHELDIAPPEPPYQPDEIYDALKQGEVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALDALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG 4liv A 2.70 BS02 SIN A 1 M146 S148 V156 H159 R174 W176 H221 N231 M111 S113 V121 H124 R139 W141 H174 N184 1.14.11.- P27431 EYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSRHELDIAPPEPPYQPDEIYDALKQGEVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALDALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG 4lll A 3.04 BS01 NUC G 1 H14 T49 Q50 N51 P62 S65 R79 R87 R88 K89 H13 T48 Q49 N50 P61 S64 R78 R86 R87 K88 Q5Y812 24293644 EFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4lll A 3.04 BS02 NUC H 1 T30 E32 Q33 R59 T60 P62 T63 N66 N70 D85 T86 R87 T29 E31 Q32 R58 T59 P61 T62 N65 N69 D84 T85 R86 Q5Y812 24293644 EFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4lll B 3.04 BS02 NUC H 1 H14 Q18 Q50 G61 P62 S65 R79 R87 R88 K89 H13 Q17 Q49 G60 P61 S64 R78 R86 R87 K88 Q5Y812 24293644 EFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4lll C 3.04 BS01 NUC E 1 H14 Q18 T49 Q50 N51 G61 P62 S65 R87 R88 K89 H13 Q17 T48 Q49 N50 G60 P61 S64 R86 R87 K88 Q5Y812 24293644 EFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4lll I 3.04 BS01 NUC K 1 H14 Q18 T49 Q50 N51 P62 S65 R79 R87 R88 K89 H12 Q16 T47 Q48 N49 P60 S63 R77 R85 R86 K87 Q5Y812 24293644 FTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4lll J 3.04 BS01 NUC K 1 T30 E32 Q33 R59 T60 P62 T63 L67 N70 D85 T86 T29 E31 Q32 R58 T59 P61 T62 L66 N69 D84 T85 Q5Y812 24293644 EFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4lln B 2.84 BS02 NUC H 1 H14 Q18 T49 Q50 N51 G61 P62 S65 R69 R79 R87 R88 K89 H13 Q17 T48 Q49 N50 G60 P61 S64 R68 R78 R86 R87 K88 Q5Y812 24293644 EFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4lln C 2.84 BS01 NUC E 1 H14 Q18 T49 Q50 P62 S65 R79 R87 K89 H13 Q17 T48 Q49 P61 S64 R78 R84 K86 Q5Y812 24293644 EFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4lln D 2.84 BS01 NUC E 1 T30 E32 Q33 R59 T60 P62 T63 N70 T31 E33 Q34 R60 T61 P63 T64 N71 Q5Y812 24293644 SNEFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4lln D 2.84 BS02 NUC F 1 H14 Q50 P62 S65 R79 R88 K89 H15 Q51 P63 S66 R80 R88 K89 Q5Y812 24293644 SNEFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 4mhx A 2.00 BS01 CA A 1 D31 D32 S70 D273 N274 D10 D11 S49 D252 N253 3.10.1.1 P51688 PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSSSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNELRS 4mhx B 2.00 BS02 MG B 1 R117 Q166 R169 P170 F171 R96 Q145 R148 P149 F150 3.10.1.1 P51688 PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSSSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNELR 4mhx B 2.00 BS03 MG B 2 T421 W423 K425 D426 T400 W402 K404 D405 3.10.1.1 P51688 PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSSSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNELR 4mrw A 1.96 BS01 MRW A 1 Y524 S677 V678 I692 F696 M713 Q726 F729 Y79 S232 V233 I247 F251 M268 Q281 F284 3.1.4.17,3.1.4.35 Q9Y233 24375910 AGTSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWI 4mrz A 1.58 BS01 2ZV A 1 F696 M713 Q726 F729 F251 M268 Q281 F284 3.1.4.17,3.1.4.35 Q9Y233 24375910 AGTSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWI 4msa A 1.62 BS02 2ZM A 2 C469 Y492 R496 C24 Y47 R51 3.1.4.17,3.1.4.35 Q9Y233 24375910 AGTSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWI 4msc A 2.47 BS01 2ZT A 1 L675 I692 Y693 P712 M713 E721 V722 G725 F729 L228 I245 Y246 P265 M266 E274 V275 G278 F282 3.1.4.17,3.1.4.35 Q9Y233 24375910 TSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWI 4mse A 2.81 BS01 2ZU A 1 Y524 L675 Y693 P712 M713 E721 G725 F729 Y79 L230 Y248 P267 M268 E276 G280 F284 3.1.4.17,3.1.4.35 Q9Y233 24375910 AGTSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWI 4msh A 2.30 BS01 2D0 A 1 V678 I692 M713 Q726 F729 V232 I246 M267 Q280 F283 3.1.4.17,3.1.4.35 Q9Y233 24375910 GTSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATW 4msn A 2.30 BS01 2ZQ A 1 I692 Y693 M713 Q726 F729 I247 Y248 M268 Q281 F284 3.1.4.17,3.1.4.35 Q9Y233 24375910 AGTSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWI 4n00 A 1.80 BS01 2EX A 1 G72 Q73 G74 L91 D93 Y132 W137 F169 I171 W176 D289 G291 T292 T293 G13 Q14 G15 L32 D34 Y73 W78 F110 I112 W117 D223 G225 T226 T227 3.4.23.46 P56817 24397738 FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESRSHHHH 4n0t A 1.70 BS01 NUC B 1 R36 R38 W120 T122 N123 R148 P150 S151 R153 F154 S157 R158 R159 F160 Y162 Y186 K191 S193 N194 P195 K198 R201 T202 D203 T206 E211 M213 R215 N216 K239 N241 P243 Q246 F251 N252 N253 C254 C255 F257 R274 S283 D288 K289 K290 P291 F292 L293 R295 N296 K299 D321 S350 D351 N395 R1 R3 W85 T87 N88 R113 P115 S116 R118 F119 S122 R123 R124 F125 Y127 Y151 K156 S158 N159 P160 K163 R166 T167 D168 T171 E176 M178 R180 N181 K204 N206 P208 Q211 F216 N217 N218 C219 C220 F222 R239 S248 D253 K254 K255 P256 F257 L258 R260 N261 K264 D286 S315 D316 N360 P49960 RNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRFARIEFARYDGALAAITKTHKVVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQMNRSLLGNREISVSLADKKPFLERNEVKRLLASRNSKELETLICLFPLSDKVSPSLICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGTINDMKRYYNNQQ 4n5g A 2.11 BS01 K09 A 1 A272 W305 L330 L433 L436 F437 F438 F439 I442 G443 A10 W43 L68 L171 L174 F175 F176 F177 I180 G181 P19793 24704507 DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4n5g D 2.11 BS01 K09 D 1 I268 Q275 W305 L433 L436 F437 F438 F439 I442 G443 I6 Q13 W43 L171 L174 F175 F176 F177 I180 G181 P19793 24704507 DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4n6f A 2.25 BS01 CA A 1 D56 D58 D46 D48 D7RFL7 DEPWLKIGAREFRSRILVGIEQYDSVPLVRDVLNAAGADVFITTVDPDNRRSSLLLMDLADELPLDDFTWIGTTSFARTKESALRSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAEGMELLPFILPDLATARALEEAGCAALRVMASPVASGRGIANPAAIRELIEQIGIPVVVEGGIGSARHVAEAMELGASATLVNTALVRAESPLLMAAAMRQAALAGLLSYESGPMPEV 4n6f A 2.25 BS02 CA A 2 D68 D71 E72 D58 D61 E62 D7RFL7 DEPWLKIGAREFRSRILVGIEQYDSVPLVRDVLNAAGADVFITTVDPDNRRSSLLLMDLADELPLDDFTWIGTTSFARTKESALRSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAEGMELLPFILPDLATARALEEAGCAALRVMASPVASGRGIANPAAIRELIEQIGIPVVVEGGIGSARHVAEAMELGASATLVNTALVRAESPLLMAAAMRQAALAGLLSYESGPMPEV 4n6f A 2.25 BS03 CA A 3 G188 I189 G178 I179 D7RFL7 DEPWLKIGAREFRSRILVGIEQYDSVPLVRDVLNAAGADVFITTVDPDNRRSSLLLMDLADELPLDDFTWIGTTSFARTKESALRSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAEGMELLPFILPDLATARALEEAGCAALRVMASPVASGRGIANPAAIRELIEQIGIPVVVEGGIGSARHVAEAMELGASATLVNTALVRAESPLLMAAAMRQAALAGLLSYESGPMPEV 4n6f A 2.25 BS04 F6R A 1 E31 K110 D112 R114 R162 V168 A169 E194 G195 G196 N217 T218 E21 K100 D102 R104 R152 V158 A159 E184 G185 G186 N207 T208 D7RFL7 DEPWLKIGAREFRSRILVGIEQYDSVPLVRDVLNAAGADVFITTVDPDNRRSSLLLMDLADELPLDDFTWIGTTSFARTKESALRSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAEGMELLPFILPDLATARALEEAGCAALRVMASPVASGRGIANPAAIRELIEQIGIPVVVEGGIGSARHVAEAMELGASATLVNTALVRAESPLLMAAAMRQAALAGLLSYESGPMPEV 4n6f B 2.25 BS01 CA B 1 Q32 D34 Q21 D23 D7RFL7 EPWLKIGAREFRSRILVGIEQYDSVPLVRDVLNAAGADVFITTVDPDNRRSSLLLMDLADELPLDDFTWIGTTSFARTKESALRSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAEGMELLPFILPDLATARALEEAGCAALRVMASPVASGRGIANPAAIRELIEQIGIPVVVEGGIGSARHVAEAMELGASATLVNTALVRAESPLLMAAAMRQAALAGLLSYESGPMPEVA 4n6f B 2.25 BS02 CA B 2 I184 I187 I173 I176 D7RFL7 EPWLKIGAREFRSRILVGIEQYDSVPLVRDVLNAAGADVFITTVDPDNRRSSLLLMDLADELPLDDFTWIGTTSFARTKESALRSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAEGMELLPFILPDLATARALEEAGCAALRVMASPVASGRGIANPAAIRELIEQIGIPVVVEGGIGSARHVAEAMELGASATLVNTALVRAESPLLMAAAMRQAALAGLLSYESGPMPEVA 4n6f B 2.25 BS03 F6R B 1 E31 S85 K110 D112 R114 A169 E194 G195 G196 N217 T218 E20 S74 K99 D101 R103 A158 E183 G184 G185 N206 T207 D7RFL7 EPWLKIGAREFRSRILVGIEQYDSVPLVRDVLNAAGADVFITTVDPDNRRSSLLLMDLADELPLDDFTWIGTTSFARTKESALRSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAEGMELLPFILPDLATARALEEAGCAALRVMASPVASGRGIANPAAIRELIEQIGIPVVVEGGIGSARHVAEAMELGASATLVNTALVRAESPLLMAAAMRQAALAGLLSYESGPMPEVA 4n8r A 2.03 BS01 K08 A 1 I268 A271 W305 L436 F437 F438 F439 I442 I6 A9 W43 L174 F175 F176 F177 I180 P19793 24704507 DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPH 4n8r D 2.03 BS01 K08 D 1 I268 A272 Q275 W305 L326 C432 L433 L436 F437 F438 F439 I442 I6 A10 Q13 W43 L64 C170 L171 L174 F175 F176 F177 I180 P19793 24704507 DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPH 4nev A 2.50 BS01 FAD A 1 I10 G11 G13 S14 G15 V34 D35 V36 A46 A47 G50 T51 C52 G56 C57 K60 G125 W126 G127 A159 T160 G161 R287 R290 G326 D327 M333 L334 T335 P336 A338 I7 G8 G10 S11 G12 V31 D32 V33 A43 A44 G47 T48 C49 G53 C54 K57 G122 W123 G124 A156 T157 G158 R284 R287 G323 D324 M330 L331 T332 P333 A335 1.8.1.12 Q389T8 24788386 AFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKGEKMEKLP 4nev A 2.50 BS02 2JR A 1 L17 W21 S109 M113 D116 L14 W18 S106 M110 D113 1.8.1.12 Q389T8 24788386 AFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKGEKMEKLP 4nev B 2.50 BS02 2JR B 1 L17 E18 W21 S109 Y110 G112 M113 L15 E16 W19 S107 Y108 G110 M111 1.8.1.12 Q389T8 24788386 KAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKGEKMEKL 4nev B 2.50 BS03 2JR B 2 P42 Y183 P40 Y181 1.8.1.12 Q389T8 24788386 KAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKGEKMEKL 4new A 2.80 BS01 FAD A 1 I11 G12 G14 S15 G16 I35 D36 V37 S47 G51 T52 C53 G57 C58 K61 G128 A160 S161 G162 S179 F199 I200 R288 R291 L295 G326 D327 M333 L334 T335 P336 I6 G7 G9 S10 G11 I30 D31 V32 S42 G46 T47 C48 G52 C53 K56 G123 A155 S156 G157 S174 F194 I195 R283 R286 L290 G321 D322 M328 L329 T330 P331 K4E0T9 24788386 FDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGVMIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKGEKMEKP 4new A 2.80 BS02 2JR A 1 E19 W22 S110 Y111 M114 E14 W17 S105 Y106 M109 K4E0T9 24788386 FDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGVMIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKGEKMEKP 4nfw A 2.30 BS01 MN A 1 A35 E51 E55 D98 A35 E51 E55 D98 G7RNP0 MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTK 4nfw B 2.30 BS01 MN B 1 E51 E54 E55 D98 E51 E54 E55 D98 G7RNP0 MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTK 4nfw C 2.30 BS02 MN C 2 E39 R50 E51 E54 E39 R50 E51 E54 G7RNP0 MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTK 4nfw E 2.30 BS01 MN E 1 E39 R50 E51 E39 R50 E51 G7RNP0 MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTK 4nfw F 2.30 BS01 MN F 1 A35 E51 E54 E55 D98 A35 E51 E54 E55 D98 G7RNP0 MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI 4nfw G 2.30 BS02 MN G 2 H37 E39 R50 E51 H37 E39 R50 E51 G7RNP0 MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTK 4nfw K 2.30 BS01 MN K 1 A35 G36 E51 E55 A35 G36 E51 E55 G7RNP0 MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTK 4nge A 2.70 BS01 III B 1 Q107 H108 L111 F123 F124 L127 S130 S132 T133 F134 M135 N136 A137 F138 T139 E205 R215 G236 R900 Y906 S961 Q77 H78 L81 F93 F94 L97 S100 S102 T103 F104 M105 N106 A107 F108 T109 E175 R185 G206 R848 Y854 S909 3.4.24.- Q5JRX3 AAACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSPVRPHTVEKPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4nge A 2.70 BS02 UNK C 1 G382 S449 Y450 S453 G351 S418 Y419 S422 3.4.24.- Q5JRX3 AAACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSPVRPHTVEKPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4nge A 2.70 BS03 III C 1 F344 L348 Q435 L447 Y450 L467 F313 L317 Q404 L416 Y419 L436 3.4.24.- Q5JRX3 AAACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSPVRPHTVEKPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4nge D 2.70 BS01 III E 1 H104 Q107 H108 F123 F124 L127 M135 N136 A137 F138 T139 E205 M206 R900 Y906 H73 Q76 H77 F92 F93 L96 M104 N105 A106 F107 T108 E174 M175 R850 Y856 Q5JRX3 AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4nge D 2.70 BS02 UNK F 1 Y143 S449 Y450 I451 S453 Y112 S413 Y414 I415 S417 Q5JRX3 AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4nhv A 1.99 BS01 2O6 A 1 L235 E236 M264 L235 E236 M264 2.5.1.15 Q81VW8 24650357 MKWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGESTRPGFAKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGK 4nhv B 1.99 BS01 2O6 B 1 E236 M264 E225 M253 2.5.1.15 Q81VW8 24650357 KWDYDLRCGEYTLNLNEKTLIMGILNVTPSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGESVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGKG 4nil A 2.18 BS01 2O8 A 1 L235 E236 E260 M264 L235 E236 E260 M264 2.5.1.15 Q81VW8 24650357 MKWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGESTRPGFAKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGK 4nir A 1.77 BS01 6DH A 1 W123 A127 R148 D149 N150 W123 A127 R148 D149 N150 2.5.1.15 Q81VW8 24650357 MKWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGESTRPGFAKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGK 4nir A 1.77 BS02 6DH A 2 L235 E236 E260 L235 E236 E260 2.5.1.15 Q81VW8 24650357 MKWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGESTRPGFAKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGK 4nir B 1.77 BS01 6DH B 1 E236 E260 M261 E225 E249 M250 2.5.1.15 Q81VW8 24650357 MKWDYDLRCGEYTLNLNEKTLIMGILNVTPSDGGSYNEVDAAVRHAKEMRDEGAHIIDIGGESVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAHIINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLADMIADLYDSIKIAKDAGVRDENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGKG 4nui A 1.70 BS01 CO A 1 H88 H148 H71 H131 J9ULM6 24631931 KAGCPDNGMSEEARQKFLEMHNSLRSSVALGQAKDGAGGNAPKAAKMKTMAYDCEVEKTAMNNAKQCVFKHSQPNQRKGLGENIFMSSDSGMDKAKAAEQASKAWFGELAEKGVGQNLKLTGGLFSRGVGHYTQMVWQETVKLGCYVEACSNMCYVVCQYGPAGNMMGKDIYEKGEPCSKCENCDKEKGLCSA 4o0m A 2.84 BS01 MG A 1 T295 E319 T285 E309 2.7.11.1 Q79V60 PTEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDEKTE 4o0m A 2.84 BS02 ATP A 1 T290 G291 G293 K294 T295 L296 E318 W331 R451 I472 T280 G281 G283 K284 T285 L286 E308 W321 R441 I462 2.7.11.1 Q79V60 PTEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDEKTE 4o0m A 2.84 BS03 ATP A 2 G50 T51 G52 K53 T54 L55 S90 F91 I240 G40 T41 G42 K43 T44 L45 S80 F81 I230 2.7.11.1 Q79V60 PTEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDEKTE 4o0m A 2.84 BS04 MG A 2 T54 E79 D146 T44 E69 D136 2.7.11.1 Q79V60 PTEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDEKTE 4o0m B 2.84 BS01 ATP A 1 K457 M458 R459 S461 W462 H463 K446 M447 R448 S450 W451 H452 2.7.11.1 Q79V60 TEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDE 4o0m B 2.84 BS02 ATP A 3 K225 L226 R227 T229 T230 H231 K233 K214 L215 R216 T218 T219 H220 K222 2.7.11.1 Q79V60 TEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDE 4o0m B 2.84 BS03 MG B 1 T295 E318 E319 T284 E307 E308 2.7.11.1 Q79V60 TEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDE 4o0m B 2.84 BS04 ATP B 1 T290 G291 T292 G293 K294 T295 L296 E318 W331 R451 I472 T473 T279 G280 T281 G282 K283 T284 L285 E307 W320 R440 I461 T462 2.7.11.1 Q79V60 TEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDE 4o0m B 2.84 BS06 ATP B 2 S49 G50 G52 K53 T54 L55 S90 F91 I240 S38 G39 G41 K42 T43 L44 S79 F80 I229 2.7.11.1 Q79V60 TEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVDE 4o0m C 2.84 BS02 ATP B 3 F200 K225 L226 R227 T229 T230 H231 F190 K215 L216 R217 T219 T220 H221 2.7.11.1 Q79V60 PTEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVD 4o0m C 2.84 BS03 ATP C 1 T290 G291 T292 G293 K294 T295 L296 W331 T415 R451 I472 T280 G281 T282 G283 K284 T285 L286 W321 T405 R441 I462 2.7.11.1 Q79V60 PTEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVD 4o0m C 2.84 BS04 ATP C 2 S49 G50 T51 G52 K53 T54 L55 S90 F91 I240 S39 G40 T41 G42 K43 T44 L45 S80 F81 I230 2.7.11.1 Q79V60 PTEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVD 4o0m C 2.84 BS05 MG C 1 T54 D146 T44 D136 2.7.11.1 Q79V60 PTEQSSAEVKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIFNEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEVAGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRLAFRLKQLGVTTIMTTERVDEYGPVARFGVEEFVSDNVVILRNVLEGERRRRTVEILKLRGTTHMKGEYPFTINNGINIFPLGAMRLTQRSSNVRVSSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLETGCQQGERALLFAYEESRAQLSRNASSWGIDFEELERRGLLRIICAYPESAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGFAKQEEITGFFTNTTDQFMGSNSITESHISTITDTILLLQYVEIRGEMSRAINVFKMRGSWHDKGIREYVITEKGAEIRDSFRNFEGIISGTPTRISVD 4o6m A 1.90 BS01 CA A 1 D214 D217 D235 D202 D205 D223 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRSY 4o6m A 1.90 BS02 MPG A 1 Q176 V179 F180 Q164 V167 F168 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRSY 4o6m A 1.90 BS03 MPG A 2 L167 F180 L155 F168 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRSY 4o6m A 1.90 BS04 MPG A 3 L267 L326 F330 L255 L314 F318 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRSY 4o6m B 1.90 BS02 MPG B 1 A325 L326 A325 L326 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6m B 1.90 BS03 MPG B 2 V179 Y230 V179 Y230 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6m B 1.90 BS04 MPG B 3 A310 C311 A310 C311 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6m B 1.90 BS05 MPG B 4 F182 L186 F182 L186 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6m B 1.90 BS06 MPG B 5 L193 Y252 L193 Y252 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6m B 1.90 BS07 C5P B 1 K136 R157 P174 N175 T178 D214 G215 D217 G218 A221 R222 E227 S228 G231 A232 D235 K136 R157 P174 N175 T178 D214 G215 D217 G218 A221 R222 E227 S228 G231 A232 D235 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6n A 2.10 BS04 MPG A 1 V314 L316 V303 L305 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRSYTN 4o6n A 2.10 BS05 MPG A 2 Q176 F180 Q165 F169 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRSYTN 4o6n A 2.10 BS06 MPG A 3 V179 F182 Y230 L238 V168 F171 Y219 L227 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRSYTN 4o6n B 2.10 BS02 CA B 2 T178 D214 D235 D239 T178 D214 D235 D239 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6n B 2.10 BS03 CDP B 1 K136 Y146 R157 P174 N175 T178 D214 G215 D217 G218 A221 R222 E227 S228 G231 A232 D235 K136 Y146 R157 P174 N175 T178 D214 G215 D217 G218 A221 R222 E227 S228 G231 A232 D235 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6n B 2.10 BS04 MPG B 1 L167 T170 V172 L167 T170 V172 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6n B 2.10 BS06 MPG B 3 I163 T170 I163 T170 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4o6n B 2.10 BS07 MPG B 4 L267 V322 L326 L267 V322 L326 O27985 MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDYLIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIEKYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIKAKRTGLKPAYYDGWIAREINRKVSLRISRLLADTSVTPNQITVFSFFLSLVGSALFLLNSYLTTLLAGVIIQLHSIIDGCDGEIARLKFMESKYGAWLDGVLDRYSDFIIVFSITYVLSASNPVYWIIGFLAAFASLMIAYTGDKFVAAYMRTYSPEGFAIPITRDFRLLIIFACSVVNLPSLALVIIALLGNFEALRRIVALRS 4ock A 1.72 BS01 ANP A 1 Y27 G30 H31 I32 N33 I46 Q48 L80 Y102 K103 F104 I105 D208 K210 I227 D228 Y25 G28 H29 I30 N31 I44 Q46 L78 Y100 K101 F102 I103 D206 K208 I225 D226 2.7.1.162 T2I3Q3 ESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTVSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACQPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDEKDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETRAIVADIMEA 4oco A 2.16 BS01 GN1 A 1 G30 H31 I32 F55 I146 F149 D208 K210 D228 R246 E254 C303 R306 F307 Y317 G28 H29 I30 F53 I144 F147 D206 K208 D226 R244 E252 C301 R304 F305 Y315 2.7.1.162 T2I3Q3 ESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTVSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACQPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDEKDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETRAIVADIMEA 4ocp A 1.94 BS01 GN1 A 1 H31 I32 F55 F149 D208 K210 N213 D228 T231 R246 E254 C303 R306 F307 Y317 H29 I30 F53 F147 D206 K208 N211 D226 T229 R244 E252 C301 R304 F305 Y315 2.7.1.162 T2I3Q3 ESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTVSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACQPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDEKDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETRAIVADIMEA 4ocp A 1.94 BS02 ADP A 1 Y27 G30 I32 N33 I46 Q48 L80 Y102 K103 F104 I105 N212 N213 L215 I227 D228 Y25 G28 I30 N31 I44 Q46 L78 Y100 K101 F102 I103 N210 N211 L213 I225 D226 2.7.1.162 T2I3Q3 ESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTVSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACQPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDEKDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETRAIVADIMEA 4ocp A 1.94 BS03 MG A 1 N213 D228 N211 D226 2.7.1.162 T2I3Q3 ESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTVSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACQPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDEKDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETRAIVADIMEA 4ocq A 1.88 BS01 A2G A 1 H31 I32 I146 F149 D208 K210 R246 E254 C303 R306 F307 Y317 F318 H29 I30 I144 F147 D206 K208 R244 E252 C301 R304 F305 Y315 F316 2.7.1.162 T2I3Q3 ESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTVSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACQPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDEKDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETRAIVADIMEA 4ocv A 1.47 BS01 ANP A 1 Y27 G30 H31 I32 N33 I46 Q48 L80 K103 F104 I105 K210 N213 I227 D228 Y24 G27 H28 I29 N30 I43 Q45 L77 K100 F101 I102 K207 N210 I224 D225 2.7.1.162 B7GN78 TNEALFDVASHFALEGTVDSIEPYGDGHINTTYLVTTDGPRYILQRMNTGIFPDTVNLMRNVELVTSTLKAQGKETLDIVRTTSGDTWAEIDGGAWRVYKFIEHTMSYNLVPNPDVFREAGRAFGDFQNFLSGFDANQLTETIAHFHDTPHRFEDFKKALAADELGRAAGCGPEIEFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDERDLDKVHFSTELFRAYTEGFVGELRDSITAREAELLPFSGNLLTMECGMRFLADYLEGDVYFATKYPEHNLVRSRTQIKLVREMEQRADETRAIVADVMETT 4ogq A 2.50 BS02 HEM A 1 Q47 F48 G51 M54 Y58 R83 H86 R87 A90 M93 T128 F131 G135 L138 P139 H187 T188 P192 Q46 F47 G50 M53 Y57 R82 H85 R86 A89 M92 T127 F130 G134 L137 P138 H186 T187 P191 P0A384 ANVYDWFEERLEIQAIAEDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVAEAYSSVQYIMNEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVSGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSSVGQATLTRYYSAHTFVLPWLIAVFMLFHFLMIRKQGISGPL 4ogq A 2.50 BS04 HEM A 3 V30 Y34 C35 G38 L41 F203 R207 G210 I211 V29 Y33 C34 G37 L40 F202 R206 G209 I210 P0A384 ANVYDWFEERLEIQAIAEDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVAEAYSSVQYIMNEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVSGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSSVGQATLTRYYSAHTFVLPWLIAVFMLFHFLMIRKQGISGPL 4ogq A 2.50 BS05 8K6 A 1 V197 F198 L200 F201 V196 F197 L199 F200 P0A384 ANVYDWFEERLEIQAIAEDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVAEAYSSVQYIMNEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVSGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSSVGQATLTRYYSAHTFVLPWLIAVFMLFHFLMIRKQGISGPL 4ogq A 2.50 BS06 8K6 A 2 V119 F201 M205 K208 V118 F200 M204 K207 P0A384 ANVYDWFEERLEIQAIAEDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVAEAYSSVQYIMNEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVSGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSSVGQATLTRYYSAHTFVLPWLIAVFMLFHFLMIRKQGISGPL 4ogq A 2.50 BS07 8K6 A 3 S130 T134 L169 A186 S129 T133 L168 A185 P0A384 ANVYDWFEERLEIQAIAEDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVAEAYSSVQYIMNEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVSGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSSVGQATLTRYYSAHTFVLPWLIAVFMLFHFLMIRKQGISGPL 4ogq A 2.50 BS08 2WM A 1 L45 F48 F52 F203 L44 F47 F51 F202 P0A384 ANVYDWFEERLEIQAIAEDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVAEAYSSVQYIMNEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVSGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSSVGQATLTRYYSAHTFVLPWLIAVFMLFHFLMIRKQGISGPL 4ogq A 2.50 BS09 CLA B 1 I98 F102 Y105 W118 V129 I97 F101 Y104 W117 V128 P0A384 ANVYDWFEERLEIQAIAEDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVAEAYSSVQYIMNEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVSGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSSVGQATLTRYYSAHTFVLPWLIAVFMLFHFLMIRKQGISGPL 4ogq A 2.50 BS10 3WM E 1 C43 M92 M96 C42 M91 M95 P0A384 ANVYDWFEERLEIQAIAEDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVAEAYSSVQYIMNEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVSGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSSVGQATLTRYYSAHTFVLPWLIAVFMLFHFLMIRKQGISGPL 4ogq B 2.50 BS01 III H 1 A2 D35 V39 G46 A49 C50 A53 L54 L57 A1 D34 V38 G45 A48 C49 A52 L53 L56 Q93SX1 ATHKKPDLSDPTLRAKLAKGMGHNYYGEPAWPNDLLYVFPIVIMGSFACIVALAVLDPAMTGEPANPFATPLEILPEWYLYPVFQILRSLPNKLLGVLAMASVPLGLILVPFIENVNKFQNPFRRPVATTVFLFGTLVTLWLGIGAALPLDKSLTLGLF 4ogq B 2.50 BS02 HEM A 4 F40 V43 I44 F39 V42 I43 Q93SX1 ATHKKPDLSDPTLRAKLAKGMGHNYYGEPAWPNDLLYVFPIVIMGSFACIVALAVLDPAMTGEPANPFATPLEILPEWYLYPVFQILRSLPNKLLGVLAMASVPLGLILVPFIENVNKFQNPFRRPVATTVFLFGTLVTLWLGIGAALPLDKSLTLGLF 4ogq B 2.50 BS03 2WM A 1 I44 F48 I43 F47 Q93SX1 ATHKKPDLSDPTLRAKLAKGMGHNYYGEPAWPNDLLYVFPIVIMGSFACIVALAVLDPAMTGEPANPFATPLEILPEWYLYPVFQILRSLPNKLLGVLAMASVPLGLILVPFIENVNKFQNPFRRPVATTVFLFGTLVTLWLGIGAALPLDKSLTLGLF 4ogq B 2.50 BS04 8K6 B 1 L36 F40 P41 L35 F39 P40 Q93SX1 ATHKKPDLSDPTLRAKLAKGMGHNYYGEPAWPNDLLYVFPIVIMGSFACIVALAVLDPAMTGEPANPFATPLEILPEWYLYPVFQILRSLPNKLLGVLAMASVPLGLILVPFIENVNKFQNPFRRPVATTVFLFGTLVTLWLGIGAALPLDKSLTLGLF 4ogq B 2.50 BS05 CLA B 1 Y80 P83 V84 A102 V104 L108 I109 V132 F133 G136 V139 T140 Y79 P82 V83 A101 V103 L107 I108 V131 F132 G135 V138 T139 Q93SX1 ATHKKPDLSDPTLRAKLAKGMGHNYYGEPAWPNDLLYVFPIVIMGSFACIVALAVLDPAMTGEPANPFATPLEILPEWYLYPVFQILRSLPNKLLGVLAMASVPLGLILVPFIENVNKFQNPFRRPVATTVFLFGTLVTLWLGIGAALPLDKSLTLGLF 4ogq C 2.50 BS01 III H 1 Q38 S39 L41 Q250 V255 I259 V262 M266 Q269 V270 V273 L274 K276 K277 E280 Q38 S39 L41 Q242 V247 I251 V254 M258 Q261 V262 V265 L266 K268 K269 E272 Q93SW9 YPFWAQQTYPETPREPTGRIVCANCHLAAKPTEVEVPQSVLPDTVFKAVVKIPYDTSVQQVGADGSKVGLNVGAVLMLPEGFKIAPEDRIPEELKEEIGDVYFQPYGEDKDNIVIVGPLPGEQYQEIVFPVLSPNPANDKNIHFGKYSVHVGGNRGRGQVYPTGEKSNNNLYSAAATGTISKIAKQEGEDGSVKYLVDISDTIPAGPELIVSEGQAVTAGDALTNNPNVGGFGQLDAEIVLQDANRVGWLIAFVALVMLAQVMLVLKKKQVEKVQAAEMNF 4ogq C 2.50 BS02 HEM C 1 Y1 P2 W4 A5 C22 C25 H26 Q60 L70 N71 V72 G73 A74 V75 N154 G156 R157 G158 V160 Y161 Y1 P2 W4 A5 C22 C25 H26 Q60 L70 N71 V72 G73 A74 V75 N154 G156 R157 G158 V160 Y161 Q93SW9 YPFWAQQTYPETPREPTGRIVCANCHLAAKPTEVEVPQSVLPDTVFKAVVKIPYDTSVQQVGADGSKVGLNVGAVLMLPEGFKIAPEDRIPEELKEEIGDVYFQPYGEDKDNIVIVGPLPGEQYQEIVFPVLSPNPANDKNIHFGKYSVHVGGNRGRGQVYPTGEKSNNNLYSAAATGTISKIAKQEGEDGSVKYLVDISDTIPAGPELIVSEGQAVTAGDALTNNPNVGGFGQLDAEIVLQDANRVGWLIAFVALVMLAQVMLVLKKKQVEKVQAAEMNF 4ogq D 2.50 BS01 FES D 1 C108 H110 L111 C113 C126 C128 H129 S131 C95 H97 L98 C100 C113 C115 H116 S118 1.10.9.1 Q93SX0 DVPDMGRRQFMNLLTFGTVTGVALGALYPVVNYFIPPAAGGAGGGTTAKDELGNDVSVSKFLESHNVGDRTLVQGLKGDPTYIVAITDYGINAVCTHLGCVVPWNAAENKFKCPCHGSQYDATGKVVRGPAPKSLALSHAKTENDKIVLTSWTETDFRTGEEPWWS 4ogq D 2.50 BS02 2WD D 1 Y36 V39 I43 Y28 V31 I35 1.10.9.1 Q93SX0 DVPDMGRRQFMNLLTFGTVTGVALGALYPVVNYFIPPAAGGAGGGTTAKDELGNDVSVSKFLESHNVGDRTLVQGLKGDPTYIVAITDYGINAVCTHLGCVVPWNAAENKFKCPCHGSQYDATGKVVRGPAPKSLALSHAKTENDKIVLTSWTETDFRTGEEPWWS 4ogq E 2.50 BS01 3WM E 1 A3 I4 Y7 I8 A3 I4 Y7 I8 Q8YVQ2 MLAIVAYIGFLALFTGIAAGLLFGLRSAKIL 4ogq E 2.50 BS02 1O2 F 1 I8 A12 T15 G16 F23 I8 A12 T15 G16 F23 Q8YVQ2 MLAIVAYIGFLALFTGIAAGLLFGLRSAKIL 4ogq F 2.50 BS01 3WM E 1 E4 A8 L11 V18 E4 A8 L11 V18 P0A3Y1 MSGELLNAALLSFGLIFVGWALGALLLKIQGA 4ogq F 2.50 BS02 2WA F 1 M1 S2 L5 A9 F13 M1 S2 L5 A9 F13 P0A3Y1 MSGELLNAALLSFGLIFVGWALGALLLKIQGA 4ogq F 2.50 BS03 1O2 F 1 K28 I29 G31 K28 I29 G31 P0A3Y1 MSGELLNAALLSFGLIFVGWALGALLLKIQGA 4ogq G 2.50 BS01 2WA F 1 V2 L11 I14 V2 L11 I14 P58246 MVEPLLSGIVLGLIVVTLAGLFYAAYKQYKRPNELGG 4ohv A 2.30 BS01 ANP A 1 E16 R18 F39 R56 A58 T123 D124 V125 G126 K127 T128 T129 D151 S282 G284 E286 R288 R293 E14 R16 F37 R54 A56 T116 D117 V118 G119 K120 T121 T122 D144 S275 G277 E279 R281 R286 P52874 EENVQEFVLKEDCELRFAAGDDSDVCLELVKGYAEIFGTELLLNKKYTFPAKSRVAAFTWKGATIELVGTTESAYVAESTPMVIYLNIHAAMEEVRKKREEQAKAKGPRLLLVGPTDVGKTTVSRILCNYSVRQGRTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFERNQPIVFNFGHTSPSANLSLYEALFKEMATTLNAQIQENDEAKIGGMIINTCGWVDGEGYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTGQIRSKMRGENVHRYFYGTRANNLYPFTFDVSFDDVTLCKIGKLVIMEPSADIKHHLFAFSRSTKADENVLKSPVFGFCLVTEVDLEKRTMSILCPQRTIPSKVLVFSDITHLD 4ohw A 2.30 BS01 ATP A 1 E16 R18 F39 R56 A58 T123 D124 V125 G126 K127 T128 T129 S282 G284 R288 R293 E13 R15 F36 R53 A55 T116 D117 V118 G119 K120 T121 T122 S275 G277 R281 R286 P52874 ENVQEFVLKEDCELRFAAGDDSDVCLELVKGYAEIFGTELLLNKKYTFPAKSRVAAFTWKGATIELVGTTESAYVAESTPMVIYLNIHAAMEEVRKKREEQAAKAKGPRLLLVGPTDVGKTTVSRILCNYSVRQGRTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFERNQPIVFNFGHTSPSANLSLYEALFKEMATTLNAQIQENDEAKIGGMIINTCGWVDGEGYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTGQIRSKMRGENVHRYFYGTRANNLYPFTFDVSFDDVTLCKIGHETKLVIMEPSADIKHHLFAFSRSTKADENVLKSPVFGFCLVTEVDLEKRTMSILCPQRTIPSKVLVFSDITHLD 4ohx A 1.98 BS01 ADP A 1 E16 R18 R56 A58 D124 V125 G126 K127 T128 T129 S282 G284 R288 E13 R15 R53 A55 D117 V118 G119 K120 T121 T122 S275 G277 R281 P52874 ENVQEFVLKEDCELRFAAGDDSDVCLELVKGYAEIFGTELLLNKKYTFPAKSRVAAFTWKGATIELVGTTESAYVAESTPMVIYLNIHAAMEEVRKKREEQAAKAKGPRLLLVGPTDVGKTTVSRILCNYSVRQGRTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFERNQPIVFNFGHTSPSANLSLYEALFKEMATTLNAQIQENDEAKIGGMIINTCGWVDGEGYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTGQIRSKMRGENVHRYFYGTRANNLYPFTFDVSFDDVTLCKIGHETKLVIMEPSADIKHHLFAFSRSTKADENVLKSPVFGFCLVTEVDLEKRTMSILCPQRTIPSKVLVFSDITHLD 4ohy A 2.00 BS01 NUC B 1 T123 D151 G153 Q154 T191 S192 S194 C231 G232 W233 R293 R297 T116 D144 G146 Q147 T184 S185 S187 C224 G225 W226 R286 R290 P52874 EENVQEFVLKEDCELRFAAGDDSDVCLELVKGYAEIFGTELLLNKKYTFPAKSRVAAFTWKGATIELVGTTESAYVAESTPMVIYLNIHAAMEEVRKKREEQAKAKGPRLLLVGPTDVGKTTVSRILCNYSVRQGRTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFERNQPIVFNFGHTSPSANLSLYEALFKEMATTLNAQIQENDEAKIGGMIINTCGWVDGEGYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTGQIRSKMRGENVHRYFYGTRANNLYPFTFDVSFDDVTLCKIGETKLVIMEPSADIKHHLFAFSRSTKADENVLKSPVFGFCLVTEVDLEKRTMSILCPQRTIPSKVLVFSDITHLD 4oi0 A 2.20 BS02 ADP A 1 E16 R56 A58 D124 V125 G126 K127 T128 T129 S282 G284 V285 E286 R288 E13 R53 A55 D116 V117 G118 K119 T120 T121 S274 G276 V277 E278 R280 P52874 ENVQEFVLKEDCELRFAAGDDSDVCLELVKGYAEIFGTELLLNKKYTFPAKSRVAAFTWKGATIELVGTTESAYVAESTPMVIYLNIHAAMEEVRKKREEQAKAKGPRLLLVGPTDVGKTTVSRILCNYSVRQGRTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFERNQPIVFNFGHTSPSANLSLYEALFKEMATTLNAQIQENDEAKIGGMIINTCGWVDGEGYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTGQIRSKMRGENVHRYFYGTRANNLYPFTFDVSFDDVTLCKIGTKLVIMEPSADIKHHLFAFSRSTKADENVLKSPVFGFCLVTEVDLEKRTMSILCPQRTIPSKVLVFSDITHLD 4oi0 A 2.20 BS03 ALF A 1 T123 D124 K127 D151 Q154 G232 R288 R293 T115 D116 K119 D143 Q146 G224 R280 R285 P52874 ENVQEFVLKEDCELRFAAGDDSDVCLELVKGYAEIFGTELLLNKKYTFPAKSRVAAFTWKGATIELVGTTESAYVAESTPMVIYLNIHAAMEEVRKKREEQAKAKGPRLLLVGPTDVGKTTVSRILCNYSVRQGRTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFERNQPIVFNFGHTSPSANLSLYEALFKEMATTLNAQIQENDEAKIGGMIINTCGWVDGEGYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTGQIRSKMRGENVHRYFYGTRANNLYPFTFDVSFDDVTLCKIGTKLVIMEPSADIKHHLFAFSRSTKADENVLKSPVFGFCLVTEVDLEKRTMSILCPQRTIPSKVLVFSDITHLD 4oi2 A 2.60 BS01 ADP A 1 E16 R18 F39 R56 A58 D124 V125 G126 K127 T128 T129 S282 G284 V285 R288 E14 R16 F37 R54 A56 D117 V118 G119 K120 T121 T122 S275 G277 V278 R281 P52874 EENVQEFVLKEDCELRFAAGDDSDVCLELVKGYAEIFGTELLLNKKYTFPAKSRVAAFTWKGATIELVGTTESAYVAESTPMVIYLNIHAAMEEVRKKREEQAKAKGPRLLLVGPTDVGKTTVSRILCNYSVRQGRTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFERNQPIVFNFGHTSPSANLSLYEALFKEMATTLNAQIQENDEAKIGGMIINTCGWVDGEGYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTGQIRSKMRGENVHRYFYGTRANNLYPFTFDVSFDDVTLCKIGETKLVIMEPSADIKHHLFAFSRSTKADENVLKSPVFGFCLVTEVDLEKRTMSILCPQRTIPSKVLVFSDITHLD 4oi4 A 2.40 BS01 III B 1 Q154 T168 A175 P177 S179 Q191 S192 L193 T194 S195 G196 A197 H201 N202 Q204 P205 M206 K208 V232 Q235 R236 L239 Q242 E331 Y332 L341 S342 F390 I405 L406 P426 V427 P428 P432 Q137 T151 A158 P160 S162 Q174 S175 L176 T177 S178 G179 A180 H184 N185 Q187 P188 M189 K191 V215 Q218 R219 L222 Q225 E314 Y315 L324 S325 F373 I388 L389 P409 V410 P411 P415 2.7.1.78 Q08685 TGDNEWHKLVIPKGSDWQIDLKAEGKLIVKVNSGIVEIFGTELAVDDEYTFQNWKFPIYAVEETELLWKCPDLTTNTITVKPNHTMKYIYNLHFMLEKIRMSNFEGPRVVIVGGSQTGKTSLSRTLCSYALKFNAYQPLYINLDPQQPIFTVPGCISATPISDILDAQLPTWGQSLTSGATLLHNKQPMVKNFGLERINENKDLYLECISQLGQVVGQRLHLDPQVRRSGCIVDTPSISQLDENLAELHHIIEKLNVNIMLVLCSETDPLWEKVKKTFGPELGNNNIFFIPKLDGVSAVDDVYKRSLQRTSIREYFYGSLDTALSPYAIGVDYEDLTIWKPSNVFDNEVGRVELFPVTITPSNLQHAIIAITFAERRADQATVIKSPILGFALITEVNEKRRKLRVLLPVPGRLPSKAMILTSYRYLE 4oi4 A 2.40 BS02 ATP A 1 D33 Q35 F56 K72 P74 S132 Q133 T134 G135 K136 T137 S138 S254 D311 G312 V313 S314 K321 D16 Q18 F39 K55 P57 S115 Q116 T117 G118 K119 T120 S121 S237 D294 G295 V296 S297 K304 2.7.1.78 Q08685 TGDNEWHKLVIPKGSDWQIDLKAEGKLIVKVNSGIVEIFGTELAVDDEYTFQNWKFPIYAVEETELLWKCPDLTTNTITVKPNHTMKYIYNLHFMLEKIRMSNFEGPRVVIVGGSQTGKTSLSRTLCSYALKFNAYQPLYINLDPQQPIFTVPGCISATPISDILDAQLPTWGQSLTSGATLLHNKQPMVKNFGLERINENKDLYLECISQLGQVVGQRLHLDPQVRRSGCIVDTPSISQLDENLAELHHIIEKLNVNIMLVLCSETDPLWEKVKKTFGPELGNNNIFFIPKLDGVSAVDDVYKRSLQRTSIREYFYGSLDTALSPYAIGVDYEDLTIWKPSNVFDNEVGRVELFPVTITPSNLQHAIIAITFAERRADQATVIKSPILGFALITEVNEKRRKLRVLLPVPGRLPSKAMILTSYRYLE 4ot5 A 1.55 BS01 481 A 1 L408 G409 T410 G411 Q412 F413 V416 A428 K430 T474 E475 Y476 M477 A478 N479 G480 E488 D521 N526 L528 D539 V546 Y551 L13 G14 T15 G16 Q17 F18 V21 A33 K35 T79 E80 Y81 M82 A83 N84 G85 E93 D126 N131 L133 D144 V151 Y156 2.7.10.2 Q06187 24712864 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREARHAFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 4ot6 A 2.05 BS01 2V1 A 1 E407 L408 G409 T410 V416 A428 E475 Y476 M477 A478 G480 N484 L528 E14 L15 G16 T17 V23 A35 E82 Y83 M84 A85 G87 N91 L135 2.7.10.2 Q06187 24712864 SWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREARHAFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 4otq A 1.55 BS01 2V2 A 1 L408 G409 T410 G411 Q412 F413 V416 A428 K430 T474 E475 Y476 M477 A478 G480 D521 N526 L528 D539 L542 S543 V546 Y551 L13 G14 T15 G16 Q17 F18 V21 A33 K35 T79 E80 Y81 M82 A83 G85 D126 N131 L133 D144 L147 S148 V151 Y156 2.7.10.2 Q06187 24712864 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREARHAFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 4otr A 1.95 BS01 2V3 A 1 L408 G409 T410 G411 Q412 F413 V416 A428 K430 T474 E475 Y476 M477 A478 G480 N526 L528 S538 D539 S543 V546 Y551 L13 G14 T15 G16 Q17 F18 V21 A33 K35 T79 E80 Y81 M82 A83 G85 N131 L133 S143 D144 S148 V151 Y156 2.7.10.2 Q06187 24712864 EIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREARHAFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 4ots A 1.70 BS01 ATP A 1 D156 G157 D155 G156 Q30C70 ADVAGTSNRDFRGREQRLYNSEQYNYNNSLNGEVSLWVYAYYSDGSVLVRNCNSQYKVGISECFKSLKEVRVGQNNDPYDEQEVNNGVYYPNGGEPTKFHSNAKPRAIQIIFSPSVNVHTIKMAKGNSVSIPKDYLQRSHPWEATGVKYRKIHVDGEIVGYSHYFELPHEYNSISLSVSGVHKNPSSYNVAAPHNIMDVFQSCDLALKFSNRYWCELELINHYISAYAYPYLDINNHKYGVPLNGRQ 4oz1 A 1.74 BS01 III C 1 V412 P414 V1 P3 Q14498 24795046 VQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPS 4oz1 A 1.74 BS02 LYS A 1 H451 A480 H40 A69 Q14498 24795046 VQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPS 4oz1 B 1.74 BS01 III C 1 M425 E439 D443 E446 E447 L485 R488 W489 F490 A491 G492 M12 E26 D30 E33 E34 L72 R75 W76 F77 A78 G79 Q14498 24795046 PLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSR 4oz6 A 2.79 BS01 III B 1 N74 L93 H197 T199 E200 A201 N74 L93 H166 T168 E169 A170 5.99.1.3 P72065 24778214 AITGDALVALPEGESVRIADIVPGARPNSDNAIDLKVLDRHGNPVLADRLFHSGEHPVYTVRTVEGLRVTGTANHPLLCLVDVAGVPTLLWKLIDEIKPGDYAVIQRSAFVPGLVRFLAQAIADELTDGRFYYAKVASVTDAGVQPVYSLRVDACDAFITNGFVSHNTEAP 4oz6 A 2.79 BS02 MG A 1 I94 D95 I97 V169 I94 D95 I97 V139 5.99.1.3 P72065 24778214 AITGDALVALPEGESVRIADIVPGARPNSDNAIDLKVLDRHGNPVLADRLFHSGEHPVYTVRTVEGLRVTGTANHPLLCLVDVAGVPTLLWKLIDEIKPGDYAVIQRSAFVPGLVRFLAQAIADELTDGRFYYAKVASVTDAGVQPVYSLRVDACDAFITNGFVSHNTEAP 4p3q A 1.35 BS01 CA A 1 V10 D11 E118 V10 D11 E118 1.5.1.3 B1XC49 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 4p3q A 1.35 BS02 NAP A 1 A6 A7 I14 G15 M16 N18 A19 M20 G43 R44 H45 T46 S49 L62 S63 S64 Q65 K76 V78 I94 G95 G96 G97 R98 V99 Y100 Q102 D122 T123 A6 A7 I14 G15 M16 N18 A19 M20 G43 R44 H45 T46 S49 L62 S63 S64 Q65 K76 V78 I94 G95 G96 G97 R98 V99 Y100 Q102 D122 T123 1.5.1.3 B1XC49 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 4p42 A 2.44 BS01 EGC A 1 F184 M272 I291 F293 Y330 L331 P334 N335 R336 I337 F22 M110 I129 F131 Y168 L169 P172 N173 R174 I175 A0FGR8 DTERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGANTHLSTFSFTKVDVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDVPGLNGLSDTIILDIISNYLVLPNRITVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRVGNQIFQSRVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVEKERLLDEWFTLDEVPKGKLHLRLEWLTLMPNASNLDKVLTDIGLSSALLILYLDSARNLPSSSNPNPVVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQDLEVEVRDEQHQCSLGNLKVPLSQLLTSEDMTVSQRFQLSNSGPNSTIKMKIALRVLHLE 4p42 B 2.44 BS01 EGC B 1 I181 F184 M272 Y330 L331 P334 N335 R336 I18 F21 M105 Y163 L164 P167 N168 R169 A0FGR8 TERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGANTHLSTFSFTKVDVGQQPLRINGVKVYTKRQIILDLQISFVGNCEIDLEIKRYFCRAGVKSIQIHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDVPGLNGLSDTIILDIISNYLVLPNRITVPLVSRFPVPKGVLRIHFIEAQDLPYGIIRVGNQIFQSRVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDDFLGSLMIDLIEVEKERLLDEWFTLDEVPKGKLHLRLEWLTLMPNASNLDKVLTDIKAGLSSALLILYLDSARNLPSGKKISSNPNPVVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQDLEVEVRDEQHQCSLGNLKVPLSQLLTSEDMTVSQRFQLSNSGPNSTIKMKIALRVLHLE 4pdd A 1.70 BS01 EAX A 1 T40 Y47 E79 S97 N152 R155 R176 M178 F199 N216 T9 Y16 E48 S66 N121 R124 R145 M147 F168 N185 Q12HD7 QTILKIGYTPPKDSHYGVGATTFCDEVEKGTQERYKCQHFPSSALGGEREMIESVQLGTQDLVNTSTGPLGNFVPETRIVDIPFLFRDYEHARKVMDGAIGQDLLKKMQAKGLIGLAWTENGFRHMTNSKRPILQASDAAGLKVRTMENKVHMDGYKTFGLLPTPMAFPELFTALQQGTVDGQENPIPVILSSKFSQVQKHLSLTGHVYSPAVLILSSRVWDKLSEADKKVFVAAAQKATVAQRKRVNDDEANGITQLKKDGMQVVEKVDGESFRKAVAPAYAGFAKEFGAERIAAIQAVKAE 4pdh A 1.80 BS01 EAX A 1 Q50 E82 S100 N155 R158 R179 M181 F202 N219 Q16 E48 S66 N121 R124 R145 M147 F168 N185 Q12CD8 QTTMKISISTSQNSHQGVAIDTFAKEVEKRTGGRYKVQTFYSGALGGERESIEAVQLGTQELAFSSTGPVPNFVPETKILDVPFLFRDKAHARAVLDGPIGQDLLGKFDAKGFKALAWGENGFRHMTNSKRDVKGPEDLKGLKMRTMENPVHIAAYKGFGIITTPMAFPEVFTALQQGTVDGQENPLSVIIASKFDQVQKHLSLTGHVYSPCIWVMNKAVFDKLSAADKQAFLDAAKEGTKANRARVDEDDAKGVADLRAKGMTVIDNIDKSKFVTALAPVNAEFEKQFGKANIEKIRNYK 4pe3 A 1.35 BS01 ZN A 1 E173 D231 Y232 E125 D183 Y184 A3PQU4 HHFRFQSSDPAGNPNFELQHVFADKVKELTNGEVTIELMPVGTIVDYKETPDAIQAGLIDGHITDTSYFAGRDPAFGLIANPVGAWADPAQMIDFVENGGGKELMNELINPYGLQFIGVSTPGLEAFVSKVPLDTVEDLKGVKVRSPEGLIANVFAAAGANPVNLPSSEVYTSLDKGVIDAADYSVFSVNQDTGMNDIAPHPVYPGFHSLPLVEVSMNKQKWDALTPELQAKITEAQKIFQQTQIDTLHQRDLEAVEAAKAGGKITVHDWSDEERAKFRGIARGEWEKVAGQSEMAQKVYDTLVTYLKDKGLMAE 4pe3 A 1.35 BS02 ZN A 2 E321 E322 E273 E274 A3PQU4 HHFRFQSSDPAGNPNFELQHVFADKVKELTNGEVTIELMPVGTIVDYKETPDAIQAGLIDGHITDTSYFAGRDPAFGLIANPVGAWADPAQMIDFVENGGGKELMNELINPYGLQFIGVSTPGLEAFVSKVPLDTVEDLKGVKVRSPEGLIANVFAAAGANPVNLPSSEVYTSLDKGVIDAADYSVFSVNQDTGMNDIAPHPVYPGFHSLPLVEVSMNKQKWDALTPELQAKITEAQKIFQQTQIDTLHQRDLEAVEAAKAGGKITVHDWSDEERAKFRGIARGEWEKVAGQSEMAQKVYDTLVTYLKDKGLMAE 4pet A 1.90 BS01 PYR A 1 F49 Y101 Y102 Q158 R179 P181 E216 W217 E241 L246 F19 Y71 Y72 Q128 R149 P151 E186 W187 E211 L216 Q48AL6 DKKYRWKLAETWGPNFPIFGDATKNMAKMVKEMSNGRLTIRIDSSNKHKSALGIFDFVKSGQYQMGHSASYYWKGKNFNTMFFTTVPFGMIASEQHAWFYYGGGMELMKKVYDQYGIMSFPGGNTGNQMGGWFKKEINSVEDLKGLKMRIPGFAGEVLAKLGAKPTNIPSGELYTALERNTIDALEWVGPSLDLRMGFHKIAPYYYTGWHEPGTELQFMVNQKAYNSLPKDLQKILTVAMKAAAYDMYSQSMHASGVNLASLKKDYPNVQMRSFPKPVMEAIVQANDELLEEFAAKDPMTAEILKSLNDYKHQIRAWTNLSDRAYLDNF 4pet A 1.90 BS02 CA A 1 Y101 Q158 E216 W217 E241 Y71 Q128 E186 W187 E211 Q48AL6 DKKYRWKLAETWGPNFPIFGDATKNMAKMVKEMSNGRLTIRIDSSNKHKSALGIFDFVKSGQYQMGHSASYYWKGKNFNTMFFTTVPFGMIASEQHAWFYYGGGMELMKKVYDQYGIMSFPGGNTGNQMGGWFKKEINSVEDLKGLKMRIPGFAGEVLAKLGAKPTNIPSGELYTALERNTIDALEWVGPSLDLRMGFHKIAPYYYTGWHEPGTELQFMVNQKAYNSLPKDLQKILTVAMKAAAYDMYSQSMHASGVNLASLKKDYPNVQMRSFPKPVMEAIVQANDELLEEFAAKDPMTAEILKSLNDYKHQIRAWTNLSDRAYLDNF 4pet B 1.90 BS01 PYR B 1 F49 Y101 Y102 Q158 R179 P181 E216 W217 E241 F18 Y70 Y71 Q127 R148 P150 E185 W186 E210 Q48AL6 KKYRWKLAETWGPNFPIFGDATKNMAKMVKEMSNGRLTIRIDSSNKHKSALGIFDFVKSGQYQMGHSASYYWKGKNFNTMFFTTVPFGMIASEQHAWFYYGGGMELMKKVYDQYGIMSFPGGNTGNQMGGWFKKEINSVEDLKGLKMRIPGFAGEVLAKLGAKPTNIPSGELYTALERNTIDALEWVGPSLDLRMGFHKIAPYYYTGWHEPGTELQFMVNQKAYNSLPKDLQKILTVAMKAAAYDMYSQSMHASGVNLASLKKDYPNVQMRSFPKPVMEAIVQANDELLEEFAAKDPMTAEILKSLNDYKHQIRAWTNLSDRAYLDNF 4pf4 A 1.13 BS01 MG A 1 K42 D161 K43 D162 2.7.11.1 P53355 HMTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKP 4pf6 A 1.75 BS01 KDO A 1 T34 P35 A36 R42 Q71 S89 L145 R148 R173 P175 W180 F196 N213 T9 P10 A11 R17 Q46 S64 L120 R123 R148 P150 W155 F171 N188 Q16C67 DKITLRMSTPASETDQRSVALAEVFAPAVAGFATYQPHYNASLIAQNSELEAIASGDLEMSIASAQELAQFFPEFSIFATGYVHQSAEHQVAVFNDPLMDPFKKTVEDELGIKLLSVMYLGQRHVNLRQTKEELTVTTPADLAGVNLRMPGTDAWQFLGKALGANPTPMAFTEIYTALQTGSVDGQDNPLPTVVDAKFYEVTNQVALTGHLVDLNYIAFSKAVWDGLSPEQQEIVQTAADAAAQSGREKQLAKEQELVSFLEEQGMEIYAPDLDAFRTHVQEQYVGSEFAASWPEGVLDKINALG 4pf8 A 1.50 BS01 GTR A 1 I32 H33 Q71 S89 R147 R168 M170 F191 N208 N209 S212 E235 I7 H8 Q46 S64 R122 R143 M145 F166 N183 N184 S187 E210 A3T0C3 DWRGWNIHVEDYPVSHGMEAFMEEVTEKTGGEIKGKVFHAGVLGSQPDAIEQLRLGIMDFGVFSLGPMGQAVPATNVVSLPFVFKSVPQMYELMDGEPGAALGKALEEKGIVALGYYDAGARSFYNSVKPINTPEDVQGMKVRVMNNDLFVGMIESMGGNATPMAFAEVYQSIKTGVVDGAENNPPSYESTSHFEVAKYYSLTQHLIIPECLCMSKKTFDGLTPEQQEIVKTAGKNSTDLQRKLWGEREAASMKIIMDGGVEVNEIADKSAFQEAMVPVYEKYLAANPEMTDLVNLFRNA 4pfb A 2.70 BS01 G3P A 1 K32 F33 E37 R148 R168 P170 Y191 S212 K9 F10 E14 R125 R145 P147 Y168 S189 Q8RE65 ARVIKVTTKFVDDEQTAKSLVKVVEAINQRSNGTLELQLFTSGTLPIGKDGMEQVANGSDWILVDGVNFLGDYVPDYNAVTGPMLYQSFEEYLRMVKTPLVQDLNAQALEKGIKVLSLDWLFGFRNIEAKKPIKTPEDMKGLKLRVPTSQLYTFTIEAMGGNPVAMPYPDTYAALQQGVIDGLEGSILSFYGTKQYENVKEYSLTRHLLGVSAVCISKKCWDSLTDEQRTIIQEEFDKGALDNLTETEKLEDEYAQKLKDNGVTFHEVDAEAFNKAVAPVYDKFPKWTPGIYDKIMENLTQIREDIKN 4ps3 A 2.90 BS01 2WH A 1 P810 W812 E814 T827 I831 K833 Y867 I879 E880 I881 V882 K883 D884 A885 M953 I963 D964 P574 W576 E578 T591 I595 K597 Y631 I643 E644 I645 V646 K647 D648 A649 M717 I727 D728 2.7.1.153,2.7.11.1 P48736 24754609 SEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTKMAKQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCRLLYYVNLLLIDHRFLLRRGEYVLHMWQISGFNADKLTSATNPDKENSMSISILLDNHPIARAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVL 4ps7 A 2.69 BS01 2WJ A 1 W812 I831 K833 Y867 I879 E880 I881 V882 A885 I963 D964 W576 I595 K597 Y631 I643 E644 I645 V646 A649 I727 D728 2.7.1.153,2.7.11.1 P48736 24754609 SEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTKMAKQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCRLLYYVNLLLIDHRFLLRRGEYVLHMWQISGFNADKLTSATNPDKENSMSISILLDNHPIARAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVL 4ps8 A 2.99 BS01 2WK A 1 W812 I831 K833 L838 D841 Y867 I879 E880 I881 V882 A885 M953 I963 D964 W576 I595 K597 L602 D605 Y631 I643 E644 I645 V646 A649 M717 I727 D728 2.7.1.153,2.7.11.1 P48736 24754609 SEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTKMAKQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCRLLYYVNLLLIDHRFLLRRGEYVLHMWQISGFNADKLTSATNPDKENSMSISILLDNHPIARAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVL 4psy A 0.85 BS01 NAP A 1 A6 A7 I14 G15 N18 A19 M20 W22 G43 R44 H45 T46 L62 S63 S64 Q65 K76 I94 G96 G97 R98 V99 Y100 Q102 T123 A6 A7 I14 G15 N18 A19 M20 W22 G43 R44 H45 T46 L62 S63 S64 Q65 K76 I94 G96 G97 R98 V99 Y100 Q102 T123 U6N356 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 4psy A 0.85 BS03 MN A 2 S135 E154 S135 E154 U6N356 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 4pth A 0.85 BS02 MN A 1 D116 A117 E118 H149 D116 A117 E118 H149 1.5.1.3 B1XC49 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 4pth A 0.85 BS03 MN A 2 S135 S138 E154 S135 S138 E154 1.5.1.3 B1XC49 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 4ptj A 1.05 BS03 MN A 2 L110 L112 E154 I155 L156 L110 L112 E154 I155 L156 1.5.1.3 B1XC49 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 4puq A 1.60 BS01 NUC C 1 P318 A319 P204 A205 3.1.4.- Q9JJX7 SNGLEDSSTISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPPYCAYLKKRAASYTIITGNEEGYFTAILLKKGRVKFKSQEIIPFPNTKMMRNLLCVNVSLGGNEFCLMTSHLESTREHSAERIRQLKTVLGKMQEAPDSTTVIFAGDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCQYTWDTKANNNLRIPAAYKHRFDRIFFRAEEGHLIPQSLDLVGLEKLDCGRFPSDHWGLLCTLNVVL 4puq A 1.60 BS02 NUC D 1 N130 E162 H236 S239 T240 R241 D272 N274 R276 W307 L315 I317 Y321 H323 H359 N16 E48 H122 S125 T126 R127 D158 N160 R162 W193 L201 I203 Y207 H209 H245 3.1.4.- Q9JJX7 SNGLEDSSTISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPPYCAYLKKRAASYTIITGNEEGYFTAILLKKGRVKFKSQEIIPFPNTKMMRNLLCVNVSLGGNEFCLMTSHLESTREHSAERIRQLKTVLGKMQEAPDSTTVIFAGDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCQYTWDTKANNNLRIPAAYKHRFDRIFFRAEEGHLIPQSLDLVGLEKLDCGRFPSDHWGLLCTLNVVL 4puq B 1.60 BS02 GOL B 1 L134 E162 R216 S239 L13 E41 R95 S118 3.1.4.- Q9JJX7 STISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPPYCAYLKKRAASYTIITGNEEGYFTAILLKKGRVKFKSQEIIPFPNTKMMRNLLCVNVSLGGNEFCLMTSHLESTREHSAERIRQLKTVLGKMQEAPDSTTVIFAGDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCQYTWDTKANNNLRIPAAYKHRFDRIFFRAEEGHLIPQSLDLVGLEKLDCGRFPSDHWGLLCTLNVVL 4puq B 1.60 BS03 GOL B 2 P300 H302 S341 L342 P179 H181 S220 L221 3.1.4.- Q9JJX7 STISFITWNIDGLDGCNLPERARGVCSCLALYSPDVVFLQEVIPPYCAYLKKRAASYTIITGNEEGYFTAILLKKGRVKFKSQEIIPFPNTKMMRNLLCVNVSLGGNEFCLMTSHLESTREHSAERIRQLKTVLGKMQEAPDSTTVIFAGDTNLRDQEVIKCGGLPDNVFDAWEFLGKPKHCQYTWDTKANNNLRIPAAYKHRFDRIFFRAEEGHLIPQSLDLVGLEKLDCGRFPSDHWGLLCTLNVVL 4pzx A 1.80 BS01 2X5 A 1 G72 Q73 G74 D93 G95 S96 Y132 F169 I171 W176 D289 G291 T292 G16 Q17 G18 D37 G39 S40 Y76 F113 I115 W120 D230 G232 T233 3.4.23.46 P56817 24780121 RGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGALNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESRSHHHH 4q61 B 2.95 BS01 AMP B 1 V3 D28 I29 N30 N82 G88 Q89 E90 V91 H95 H97 V3 D28 I29 N30 N82 G88 Q89 E90 V91 H95 H97 P64382 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGD 4q61 C 2.95 BS01 AMP C 1 V3 F4 D28 I29 N30 L38 N82 G88 Q89 E90 H95 H97 V3 F4 D28 I29 N30 L38 N82 G88 Q89 E90 H95 H97 P64382 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSG 4q61 F 2.95 BS01 AMP F 1 F4 F26 Y27 D28 I29 N30 L38 N82 G88 Q89 E90 V91 H95 H97 F4 F26 Y27 D28 I29 N30 L38 N82 G88 Q89 E90 V91 H95 H97 P64382 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGD 4q61 I 2.95 BS01 AMP I 1 F4 F26 D28 I29 N30 L38 G88 Q89 E90 V91 H95 H97 F4 F26 D28 I29 N30 L38 G88 Q89 E90 V91 H95 H97 P64382 MNVFEKIIQGEIPCSKILENERFLSFYDINPKAKVHALVIPKQSIQDFNGITPELMAQMTSFIFEVVEKLGIKEKGYKLLTNVGKNAGQEVMHLHFHILSGD 4q6h A 1.90 BS01 III B 1 G298 L299 G300 I301 S302 I303 T304 G305 H309 S316 H319 Q322 H349 V353 L356 G15 L16 G17 I18 S19 I20 T21 G22 H26 S33 H36 Q39 H66 V70 L73 Q9HD26 GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV