2lzu A BS01 ZN A 1 C43 C46 H64 C67 C8 C11 H29 C32 Q9BT23 RAQVKETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAALHGEFYCKPHFQQLFKSKGNYDE 2lzu A BS02 ZN A 2 C70 C73 C91 H94 C35 C38 C56 H59 Q9BT23 RAQVKETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAALHGEFYCKPHFQQLFKSKGNYDE 2m8s A BS01 III B 1 H24 S25 N26 E27 Y29 E94 H24 S25 N26 E27 Y29 E94 Q60739 24628338 MAKTEEMVQTEEMETPRLSVIVTHSNERYDLLVTPQQGNSEPVVQDLAQLVEEATGVPLPFQKLIFKGKSLKEMETPLSALGMQNGCRVMLIGEKSN 3tld A 1.90 BS01 HEM A 1 L42 F43 P54 A56 L57 T60 V61 I81 K84 H85 A88 V90 H94 Y95 V98 I129 F133 L42 F43 P52 A54 L55 T58 V59 I79 K82 H83 A86 V88 H92 Y93 V96 I127 F131 P04252 23519792 MLDQQTINIIKATVPVLKEHGVTITTTFFKNLFAKHPEVRPLFDMGESLEQPKALAMTVLAAAQNIENLPAILPAVKKIAVKHCQAGVAAAHYPIVGQELLGAIKEVLGDAATDDILDAWGKAYGVIADVFIQVEADLYAQAVE 3tld B 1.90 BS01 HEM B 1 V39 L42 F43 P54 A56 L57 T60 V61 I81 K84 H85 A88 V90 H94 Y95 V98 Y126 A130 F133 V39 L42 F43 P52 A54 L55 T58 V59 I79 K82 H83 A86 V88 H92 Y93 V96 Y124 A128 F131 P04252 23519792 MLDQQTINIIKATVPVLKEHGVTITTTFFKNLFAKHPEVRPLFDMGESLEQPKALAMTVLAAAQNIENLPAILPAVKKIAVKHCQAGVAAAHYPIVGQELLGAIKEVLGDAATDDILDAWGKAYGVIADVFIQVEADLYAQAVE 3tm3 A 1.75 BS01 HEM A 1 L42 F43 E52 P54 A56 L57 T60 V61 I81 K84 H85 A88 V90 H94 Y95 V98 Y126 I129 A130 F133 L42 F43 E50 P52 A54 L55 T58 V59 I79 K82 H83 A86 V88 H92 Y93 V96 Y124 I127 A128 F131 P04252 23519792 MLDQQTINIIKATVPVLKEHGVTITTTFYKNLFAKHPEVRPLFDMGESLEQPKALAMTVLAAAQNIENLPAILPAVKKIAVKHCQAGVAAAHYPIVGQELLGAIKEVLGDAATDDILDAWGKAYGVIADVFIQVEADLYAQAVE 3tm9 A 1.72 BS01 HEM A 1 L42 F43 Q53 A56 L57 T60 V61 I81 K84 H85 A88 V90 H94 Y95 V98 Y126 F133 L42 F43 Q53 A56 L57 T60 V61 I81 K84 H85 A88 V90 H94 Y95 V98 Y126 F133 P04252 23519792 MLDQQTINIIKATVPVLKEHGVTITTTFAKNLFAKHPEVRPLFDMGRQESLEQPKALAMTVLAAAQNIENLPAILPAVKKIAVKHCQAGVAAAHYPIVGQELLGAIKEVLGDAATDDILDAWGKAYGVIADVFIQVEADLYAQAVE 3wf2 A 2.30 BS01 NDJ A 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 L274 Y306 N321 Y333 Y485 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 L246 Y278 N293 Y305 Y457 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf2 B 2.30 BS01 NDJ B 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 W273 Y306 N321 Y333 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 W245 Y278 N293 Y305 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf2 C 2.30 BS01 NDJ C 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 W273 L274 Y306 Y333 Y485 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 W245 L246 Y278 Y305 Y457 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf2 D 2.30 BS01 NDJ D 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 W273 Y333 Y485 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 W245 Y305 Y457 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf4 A 2.30 BS01 6DJ A 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 W273 L274 Y306 Y333 Y485 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 W245 L246 Y278 Y305 Y457 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYTSGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf4 B 2.30 BS01 6DJ B 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 W273 L274 Y306 Y333 Y485 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 W245 L246 Y278 Y305 Y457 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYTSGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf4 C 2.30 BS01 6DJ C 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 W273 L274 Y306 Y333 Y485 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 W245 L246 Y278 Y305 Y457 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYTSGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf4 D 2.30 BS01 6DJ D 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 W273 L274 Y333 Y485 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 W245 L246 Y305 Y457 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYTSGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wk4 A 2.11 BS01 MG A 1 D9 D11 D185 D8 D10 D184 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk4 A 2.11 BS02 S0A A 1 F267 D335 W336 M339 T360 Y383 Q384 M419 Y466 H524 W525 F266 D334 W335 M338 T359 Y382 Q383 M418 Y465 H523 W524 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk5 A 2.77 BS01 MG A 1 D9 D11 D185 D8 D10 D184 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk5 A 2.77 BS02 S0C A 1 F267 D335 W336 Y383 Q384 L408 M419 Y466 H524 F266 D334 W335 Y382 Q383 L407 M418 Y465 H523 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk6 A 2.10 BS01 MG A 1 D9 D11 D185 I186 D8 D10 D184 I185 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk6 A 2.10 BS02 S0B A 1 F267 D335 W336 Y383 L408 M419 Y466 F266 D334 W335 Y382 L407 M418 Y465 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk7 A 2.20 BS01 MG A 1 D9 D11 D185 D8 D10 D184 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk7 A 2.20 BS02 S0D A 1 F267 D335 W336 Y383 Q384 Y466 W525 F266 D334 W335 Y382 Q383 Y465 W524 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk8 A 2.20 BS01 MG A 1 D9 D11 D185 I186 D8 D10 D184 I185 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk8 A 2.20 BS02 S0E A 1 F267 Y383 F387 L408 M419 L428 D496 V498 H524 F266 Y382 F386 L407 M418 L427 D495 V497 H523 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk9 A 2.20 BS01 MG A 1 D9 D11 D185 D8 D10 D184 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wk9 A 2.20 BS02 S0F A 1 F267 Y383 F387 L397 L408 M419 L428 D496 V498 H524 F266 Y382 F386 L396 L407 M418 L427 D495 V497 H523 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wka A 2.01 BS01 MG A 1 D9 D11 D184 D185 D8 D10 D183 D184 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wka A 2.01 BS02 S0G A 1 F267 Y383 M419 D496 F497 V498 H524 W525 F266 Y382 M418 D495 F496 V497 H523 W524 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wkb A 2.20 BS01 MG A 1 D9 D11 D185 D8 D10 D184 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wkb A 2.20 BS02 S0I A 1 W336 M339 Y343 I375 Q384 Y466 M469 N472 A476 W335 M338 Y342 I374 Q383 Y465 M468 N471 A475 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wkc A 2.20 BS01 MG A 1 D9 D11 D184 D185 I186 D8 D10 D183 D184 I185 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wkc A 2.20 BS02 S0J A 1 D335 W336 M339 P361 P371 S374 I375 Q384 L499 M503 D334 W335 M338 P360 P370 S373 I374 Q383 L498 M502 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wkd A 2.48 BS01 MG A 1 D9 D11 D185 D8 D10 D184 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wkd A 2.48 BS02 S0K A 1 M310 W336 M339 Y343 A365 P371 Q384 Y466 M469 N472 W473 A476 M309 W335 M338 Y342 A364 P370 Q383 Y465 M468 N471 W472 A475 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wke A 2.75 BS01 MG A 1 D9 D11 D184 D185 D8 D10 D183 D184 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wke A 2.75 BS02 AUB A 1 F267 D335 W336 T360 Y383 L408 S415 M419 Y466 H524 W525 F266 D334 W335 T359 Y382 L407 S414 M418 Y465 H523 W524 3.3.2.10,3.1.3.76 P34913 24656800 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 3wt4 A 2.30 BS01 ZN A 1 D236 E266 H401 D236 E266 H397 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 A 2.30 BS02 ZN A 2 H82 D236 D307 H82 D236 D307 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 A 2.30 BS03 CO3 A 1 H82 D236 E265 E266 D307 H401 H82 D236 E265 E266 D307 H397 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 B 2.30 BS01 ZN B 1 H82 D236 D307 H82 D236 D307 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 B 2.30 BS02 ZN B 2 D236 E266 H401 D236 E266 H397 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 B 2.30 BS03 CO3 B 1 H82 D236 E265 E266 D307 P380 H401 H82 D236 E265 E266 D307 P376 H397 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 C 2.30 BS01 ZN C 1 D236 E266 H401 D236 E266 H396 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 C 2.30 BS02 ZN C 2 H82 D236 D307 H82 D236 D307 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 C 2.30 BS03 CO3 C 1 H82 D236 E265 E266 D307 H401 H82 D236 E265 E266 D307 H396 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 D 2.30 BS01 ZN D 1 D236 E266 H401 D236 E266 H397 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 D 2.30 BS02 ZN D 2 H82 D236 D307 H82 D236 D307 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3wt4 D 2.30 BS03 CO3 D 1 H82 D236 E265 E266 D307 H401 H82 D236 E265 E266 D307 H397 3.4.11.- Q9HYZ3 MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP 3zp4 A 1.80 BS01 TSA C 1 R7 E78 Y108 L115 R7 E78 Y107 L114 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp4 B 1.80 BS01 TSA B 1 F57 A59 K60 V73 T74 C75 F57 A59 K60 V73 T74 C75 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp4 C 1.80 BS01 TSA B 1 R7 E78 Y108 L115 R7 E78 Y107 L114 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp4 C 1.80 BS02 TSA C 1 F57 A59 R63 V73 T74 C75 F57 A59 R63 V73 T74 C75 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp4 D 1.80 BS01 TSA D 1 F57 A59 R63 V73 T74 C75 F57 A59 R63 V73 T74 C75 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp4 D 1.80 BS02 TSA F 1 R7 E78 Y108 L115 R7 E78 Y107 L114 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp4 E 1.80 BS01 TSA D 1 R7 E78 Y108 L115 R7 E78 Y107 L114 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp4 F 1.80 BS01 TSA F 1 F57 A59 V73 T74 C75 F57 A59 V73 T74 C75 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 A 1.70 BS01 PRE A 1 F57 A59 R63 V73 T74 C75 F57 A59 R63 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 A 1.70 BS02 ISJ A 1 F57 A59 K60 R63 V73 T74 C75 F57 A59 K60 R63 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 A 1.70 BS03 PRE C 1 R7 E78 Y108 L115 R7 E78 Y107 L114 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 A 1.70 BS04 ISJ C 1 R7 A9 E78 L115 R7 A9 E78 L114 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 B 1.70 BS01 PRE A 1 R7 E78 Y108 L115 R7 E78 Y107 L114 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 B 1.70 BS02 ISJ A 1 R7 E78 L115 R7 E78 L114 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 B 1.70 BS03 PRE B 1 F57 A59 R63 V73 T74 C75 F57 A59 R63 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 B 1.70 BS04 ISJ B 1 F57 A59 K60 R63 V73 T74 C75 F57 A59 K60 R63 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 C 1.70 BS01 PRE B 1 R7 E78 Y108 L115 R116 R7 E78 Y107 L114 R115 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 C 1.70 BS02 ISJ B 1 R7 E78 Y108 L115 R7 E78 Y107 L114 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 C 1.70 BS03 PRE C 1 F57 A59 R63 V73 T74 C75 F57 A59 R63 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 C 1.70 BS04 ISJ C 1 F57 A59 K60 V73 T74 C75 F57 A59 K60 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 D 1.70 BS01 PRE D 1 R7 E78 Y108 L115 R7 E78 Y107 L114 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 D 1.70 BS02 PRE D 2 F57 A59 V73 T74 C75 F57 A59 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 D 1.70 BS03 ISJ D 1 R7 E78 L115 R7 E78 L114 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 D 1.70 BS04 ISJ D 2 A59 V73 T74 C75 A59 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 E 1.70 BS01 PRE D 3 R7 E78 Y108 L115 R7 E78 Y107 L114 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 E 1.70 BS02 ISJ D 3 R7 E78 Y108 L115 R7 E78 Y107 L114 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 F 1.70 BS01 PRE D 1 F57 A59 V73 T74 C75 F57 A59 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 3zp7 F 1.70 BS02 ISJ D 1 F57 A59 K60 V73 T74 C75 F57 A59 K60 V73 T74 C75 5.4.99.5 P19080 MMIRGIRGATTVERDTEEEILQKTKQLLEKIIEENHTKPEDVVQMLLSATPDLHAVFPAKAVRELSGWQYVPVTCMQEMDVTGGLKKCIVMMTVQTDVPQEQIRHVYLEKAVVLRP 4bh7 A 2.89 BS01 III P 1 Y32 G91 N92 T93 L94 R96 Y32 G91 N92 T93 L94 R96 DIQMTQTTSSLSASLGDRVTISCRASQDISNYLNWYQQKPDGTVSLLIYYGSRLHSGVPSRFSGSGSGTDYSLTISNLEQEDIATYFCQQGNTLPRTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 4bh7 B 2.89 BS01 III P 1 Y57 K59 K65 G104 S105 Y106 Y57 K59 K65 G104 S105 Y106 EVQLQQSGAELVRAGSSVKMSCKASGYTFTSYGINWVKQRPGQGLEWIGYINPGNGYTKYNEKFKGKTTLTVDKSSSTAYMQLRSLTSEDSAVYFCARSVYYGGSYYFDYWGQGTTLTVSSAKTTPPSVYPLAPGSNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVPRD 4bh8 B 2.40 BS01 III P 1 S31 Y32 G33 Y50 N52 S99 V100 Y101 Y102 G103 Y106 S31 Y32 G33 Y50 N52 S99 V100 Y101 Y102 G103 Y106 EVQLQQSGAELVRAGSSVKMSCKASGYTFTSYGINWVKQRPGQGLEWIGYINPGNGYTKYNEKFKGKTTLTVDKSSSTAYMQLRSLTSEDSAVYFCARSVYYGGSYYFDYWGQGTTLTVSSAKTTPPSVYPLAPGSASMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVPRD 4bhe A 3.00 BS01 PLP A 1 S92 G93 V94 H121 H124 D196 A198 S223 H225 K226 S89 G90 V91 H118 H121 D193 A195 S220 H222 K223 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe B 3.00 BS01 PLP A 1 Y50 V255 S256 Y50 V252 S253 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe B 3.00 BS02 PLP B 1 S92 G93 V94 H121 H124 G170 S171 D196 A198 H199 S223 H225 K226 S89 G90 V91 H118 H121 G167 S168 D193 A195 H196 S220 H222 K223 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe C 3.00 BS01 PLP C 1 G93 V94 N97 H121 H124 G170 D196 A198 H199 S223 H225 K226 G89 V90 N93 H117 H120 G166 D192 A194 H195 S219 H221 K222 2.1.2.1,4.1.2.49 Q58992 YSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe C 3.00 BS02 PLP D 1 E52 Y60 E48 Y56 2.1.2.1,4.1.2.49 Q58992 YSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe D 3.00 BS01 PLP C 1 Y50 S256 Y50 S253 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe D 3.00 BS02 PLP D 1 S92 G93 V94 H121 S171 A198 H199 S223 H225 K226 S89 G90 V91 H118 S168 A195 H196 S220 H222 K223 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe E 3.00 BS01 PLP E 1 G93 V94 H121 G170 S171 D196 G197 A198 H199 S223 H225 K226 G91 V92 H119 G168 S169 D194 G195 A196 H197 S221 H223 K224 2.1.2.1,4.1.2.49 Q58992 YSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe E 3.00 BS02 PLP F 1 Y50 S256 N257 Y48 S254 N255 2.1.2.1,4.1.2.49 Q58992 YSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe F 3.00 BS01 PLP E 1 Y50 V255 S256 N257 Y50 V255 S256 N257 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe F 3.00 BS02 PLP F 1 S92 G93 V94 H121 G170 S171 A198 H199 S223 H225 K226 S92 G93 V94 H121 G170 S171 A198 H199 S223 H225 K226 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe G 3.00 BS01 PLP G 1 G93 V94 H121 G170 S171 A198 H199 S223 H225 K226 G93 V94 H121 G170 S171 A198 H199 S223 H225 K226 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe G 3.00 BS02 PLP H 1 Y50 V255 S256 Y50 V255 S256 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe H 3.00 BS01 PLP G 1 Y50 S256 N257 Y50 S252 N253 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe H 3.00 BS02 PLP H 1 S92 G93 H121 G170 D196 A198 H199 S223 H225 K226 S90 G91 H119 G168 D194 A196 H197 S219 H221 K222 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe I 3.00 BS01 PLP I 1 S92 G93 V94 H121 D196 A198 H199 S223 H225 K226 S90 G91 V92 H119 D194 A196 H197 S221 H223 K224 2.1.2.1,4.1.2.49 Q58992 YSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe I 3.00 BS02 PLP J 1 Y50 V255 S256 Y48 V253 S254 2.1.2.1,4.1.2.49 Q58992 YSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe J 3.00 BS01 PLP J 1 S92 G93 H121 G170 S171 D196 A198 S223 H225 K226 S92 G93 H121 G170 S171 D196 A198 S223 H225 K226 2.1.2.1,4.1.2.49 Q58992 MEYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe K 3.00 BS01 PLP K 1 S92 G93 V94 N97 H121 D196 S223 H225 K226 S90 G91 V92 N95 H119 D194 S221 H223 K224 2.1.2.1,4.1.2.49 Q58992 YSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe K 3.00 BS02 PLP L 1 V255 S256 V253 S254 2.1.2.1,4.1.2.49 Q58992 YSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe L 3.00 BS01 PLP K 1 V255 S256 V251 S252 2.1.2.1,4.1.2.49 Q58992 EYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVAAGIRGLKVINHPFDPEEMNIDADAMVKKILKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhe L 3.00 BS02 PLP L 1 S92 G93 V94 N97 H121 H124 D196 A198 S223 H225 K226 S91 G92 V93 N96 H120 H123 D192 A194 S219 H221 K222 2.1.2.1,4.1.2.49 Q58992 EYSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFKAEHANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHWKVAAGIRGLKVINHPFDPEEMNIDADAMVKKILKPKLILFGGSLFPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTKENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLEFGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKRIAIDKEKPEKVREDVKEFAKEYSTIHYSFDEGDGFKYLRFY 4bhg A 1.85 BS01 C2T A 1 Y177 W181 N191 A193 Y194 D204 Y205 N292 Y366 Y177 W181 N191 A193 Y194 D204 Y205 N292 Y366 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4bhg A 1.85 BS02 ZN A 1 H202 D204 H347 H202 D204 H347 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4bhg A 1.85 BS03 ZN A 2 C38 C40 C43 H82 C38 C40 C43 H82 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4bhg A 1.85 BS04 ZN A 3 C3 K72 C3 K72 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4bhg A 1.85 BS05 16D A 1 I68 Y75 Y83 I68 Y75 Y83 1.14.11.1 O75936 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE 4bpm A 2.08 BS01 GSH A 1 R70 R73 N74 E77 H113 Y117 R126 S127 Y130 R61 R64 N65 E68 H104 Y108 R117 S118 Y121 5.3.99.3 O14684 SPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHFLPAALRAALLGRLRTLRPW 4bpm A 2.08 BS02 LVJ A 1 A123 P124 S127 V128 Y130 T131 L132 A114 P115 S118 V119 Y121 T122 L123 5.3.99.3 O14684 SPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHFLPAALRAALLGRLRTLRPW 4c31 A 3.00 BS01 III C 1 M764 E767 L768 A771 H774 E775 Y778 M9 E12 L13 A16 H19 E20 Y23 P46674 24705649 SRKDFIDTMTRELYDAFLHERLYLIYMDSRA 4c31 A 3.00 BS02 III F 1 Y778 L779 Y23 L24 P46674 24705649 SRKDFIDTMTRELYDAFLHERLYLIYMDSRA 4c31 B 3.00 BS01 III C 1 K9 S10 Q13 V17 Y22 E23 K6 S7 Q10 V14 Y19 E20 Q6WNK7 24705649 DTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDT 4c31 B 3.00 BS02 III X 1 L8 Q11 Y15 I92 V93 D94 L5 Q8 Y12 I89 V90 D91 Q6WNK7 24705649 DTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDT 4c31 D 3.00 BS01 III C 1 Y778 L779 Y23 L24 P46674 24705649 SRKDFIDTMTRELYDAFLHERLYLIYMDSRA 4c31 D 3.00 BS02 III F 1 L768 A771 F772 H774 E775 Y778 L13 A16 F17 H19 E20 Y23 P46674 24705649 SRKDFIDTMTRELYDAFLHERLYLIYMDSRA 4c31 E 3.00 BS01 III F 1 K9 Q13 V17 Y22 E23 K6 Q10 V14 Y19 E20 Q6WNK7 24705649 DTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDT 4c31 E 3.00 BS02 III Y 1 L8 Q11 Y15 I92 V93 D94 L5 Q8 Y12 I89 V90 D91 Q6WNK7 24705649 DTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDT 4civ A 2.90 BS01 48P A 1 R19 N75 G77 G78 H81 H101 I102 S103 V105 R112 R17 N68 G70 G71 H74 H94 I95 S96 V98 R105 4.2.1.10 P0A4Z6 24689821 LIVNVINGPNLGRLGRRGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHV 4ciw A 2.20 BS01 XH2 A 1 N12 Y24 N75 G77 G78 H81 H101 I102 S103 V105 R112 N10 Y22 N73 G75 G76 H79 H99 I100 S101 V103 R110 4.2.1.10 P0A4Z6 24689821 LIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4cix A 2.90 BS01 W4N A 1 L13 L16 R18 N75 G77 G78 H81 H101 I102 S103 V105 R112 L11 L14 R16 N66 G68 G69 H72 H92 I93 S94 V96 R103 4.2.1.10 P0A4Z6 24689821 LIVNVINGPNLGRLGRGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAE 4ciy A 2.10 BS01 NDY A 1 P11 N12 R15 Y24 N75 G77 G78 H81 H101 I102 S103 V105 R112 P9 N10 R13 Y17 N68 G70 G71 H74 H94 I95 S96 V98 R105 4.2.1.10 P0A4Z6 24689821 LIVNVINGPNLGRLGRYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEH 4cml A 2.30 BS01 52N A 1 L306 K308 F311 I373 M374 N379 K380 A403 H404 Y502 K503 K516 R518 L49 K51 F54 I116 M117 N122 K123 A146 H147 Y245 K246 K259 R261 3.1.3.36 P32019 24704254 MYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVAHHH 4cml A 2.30 BS02 MG A 1 N275 E303 N18 E46 3.1.3.36 P32019 24704254 MYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVAHHH 4cmn A 3.13 BS01 PO4 A 1 N248 E278 Y477 D523 H524 N30 E60 Y257 D303 H304 3.1.3.36 Q01968 24704254 REGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNLPQLNIMKHEVVIWLGDLNYRLGMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDSVRIMDRMEN 4cmn A 3.13 BS02 MG A 1 N250 E278 L281 N32 E60 L63 3.1.3.36 Q01968 24704254 REGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNLPQLNIMKHEVVIWLGDLNYRLGMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDSVRIMDRMEN 4cq0 A 1.45 BS01 ZN A 1 H94 H96 H119 H90 H92 H115 4.2.1.1 P00918 24689792 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4cq0 A 1.45 BS02 SXS A 1 H94 H96 H119 V121 F131 V143 L198 T199 T200 W209 H90 H92 H115 V117 F126 V138 L193 T194 T195 W204 4.2.1.1 P00918 24689792 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4cqk A 1.60 BS01 PIO A 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk A 1.60 BS02 PIO C 1 I37 R40 I37 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk B 1.60 BS01 PIO B 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk B 1.60 BS02 PIO J 1 I37 R40 I37 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk C 1.60 BS01 PIO A 1 I37 R40 I37 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk C 1.60 BS02 PIO C 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk D 1.60 BS01 PIO D 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk E 1.60 BS01 PIO E 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk E 1.60 BS02 PIO N 1 I37 R40 I37 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk F 1.60 BS01 PIO F 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk F 1.60 BS02 PIO H 1 I37 R40 I37 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk G 1.60 BS01 PIO G 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk H 1.60 BS01 PIO H 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk I 1.60 BS01 PIO I 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk J 1.60 BS01 PIO J 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk K 1.60 BS01 PIO K 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk L 1.60 BS01 PIO L 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk M 1.60 BS01 PIO L 1 K36 R40 K36 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk M 1.60 BS02 PIO M 1 K4 H33 S35 K36 I37 L38 R40 K4 H33 S35 K36 I37 L38 R40 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4cqk N 1.60 BS01 PIO N 1 K4 H33 S35 K36 I37 L38 K4 H33 S35 K36 I37 L38 Q8GTM0 24692446 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 4ctj A 1.47 BS01 SAM A 1 S56 G58 G81 C82 G83 G86 W87 T104 K105 H110 K130 D131 V132 F133 D146 S50 G52 G75 C76 G77 G80 W81 T98 K99 H104 K124 D125 V126 F127 D140 2.1.1.56,2.1.1.57 A9LIE0 24704437 ETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMTHRRPTIEKDVDLGAGTR 4ctj A 1.47 BS02 3A9 A 1 L237 R241 M244 R247 L231 R235 M238 R241 2.1.1.56,2.1.1.57 A9LIE0 24704437 ETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMTHRRPTIEKDVDLGAGTR 4ctj C 1.47 BS01 SAM C 1 S56 G58 G81 C82 G83 G86 W87 T104 K105 K130 D131 V132 F133 D146 I147 S50 G52 G75 C76 G77 G80 W81 T98 K99 K124 D125 V126 F127 D140 I141 2.1.1.56,2.1.1.57 A9LIE0 24704437 ETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMTHRRPTIEKDVDLGAGTR 4ctk A 1.53 BS01 SAM A 1 S56 G58 G81 C82 G83 G86 W87 T104 K105 H110 E111 K130 D131 V132 F133 D146 I147 S50 G52 G75 C76 G77 G80 W81 T98 K99 H104 E105 K124 D125 V126 F127 D140 I141 2.1.1.56,2.1.1.57 A9LIE0 24704437 ETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMTHRRPTIEKDVDLGAGTR 4ctk A 1.53 BS02 SVN A 1 L17 L20 R22 F25 L11 L14 R16 F19 2.1.1.56,2.1.1.57 A9LIE0 24704437 ETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMTHRRPTIEKDVDLGAGTR 4ctk A 1.53 BS03 SVN A 2 N18 P152 N12 P146 2.1.1.56,2.1.1.57 A9LIE0 24704437 ETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMTHRRPTIEKDVDLGAGTR 4ctk C 1.53 BS01 SAM C 1 S56 G58 G81 C82 G83 G86 W87 T104 K105 H110 K130 D131 V132 F133 D146 I147 S50 G52 G75 C76 G77 G80 W81 T98 K99 H104 K124 D125 V126 F127 D140 I141 2.1.1.56,2.1.1.57 A9LIE0 24704437 ETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVRNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMTHRRPTIEKDVDLGAGTR 4cug A 2.96 BS01 III E 1 R56 D118 M120 H133 D135 N136 Y137 R169 S208 G210 R212 R285 R55 D117 M119 H132 D134 N135 Y136 R168 S207 G209 R211 R284 D0MK34 QLPETILGGLAPEEFLANYWQKRPLLIRQALPGFRSPITPEELAGLACEEGVTARLILEKGGAYPWEVRYGPFEPEDFVALPPTHWTLLVQEVDRLVPEVAALLETVRFVPNWRLDDIMVSYAPEGGTVGAHIDNYDVFLVQAWGRRRWQINHRPVEREELVPGLEVRLLAHFEPDAEWILEPGDVLYLPPRIPHYGVALEDCMTFSIGFRAPDQAELAEAMPRMAAWLDGGRRYADPDLTPADEPGEITPEALDQIQALLRALIDDRERLARWFGCIITEPRRGLPPEPPGRPLSAKQLHRRLQQGATLRRNAIPELAYVRHADGSATLFASGEAYELSPELADVAPLLTGRRPLTAETLRPWLERDDFLELLQTLIHSGILSLIPA 4cug A 2.96 BS02 MN A 1 H133 D135 H196 H132 D134 H195 D0MK34 QLPETILGGLAPEEFLANYWQKRPLLIRQALPGFRSPITPEELAGLACEEGVTARLILEKGGAYPWEVRYGPFEPEDFVALPPTHWTLLVQEVDRLVPEVAALLETVRFVPNWRLDDIMVSYAPEGGTVGAHIDNYDVFLVQAWGRRRWQINHRPVEREELVPGLEVRLLAHFEPDAEWILEPGDVLYLPPRIPHYGVALEDCMTFSIGFRAPDQAELAEAMPRMAAWLDGGRRYADPDLTPADEPGEITPEALDQIQALLRALIDDRERLARWFGCIITEPRRGLPPEPPGRPLSAKQLHRRLQQGATLRRNAIPELAYVRHADGSATLFASGEAYELSPELADVAPLLTGRRPLTAETLRPWLERDDFLELLQTLIHSGILSLIPA 4cug B 2.96 BS01 III F 1 T54 R56 Q92 D118 M120 V130 H133 D135 N136 Y137 L162 V168 R169 S208 G210 R212 R285 T53 R55 Q91 D117 M119 V129 H132 D134 N135 Y136 L161 V167 R168 S207 G209 R211 R284 D0MK34 QLPETILGGLAPEEFLANYWQKRPLLIRQALPGFRSPITPEELAGLACEEGVTARLILEKGGAYPWEVRYGPFEPEDFVALPPTHWTLLVQEVDRLVPEVAALLETVRFVPNWRLDDIMVSYAPEGGTVGAHIDNYDVFLVQAWGRRRWQINHRPVEREELVPGLEVRLLAHFEPDAEWILEPGDVLYLPPRIPHYGVALEDCMTFSIGFRAPDQAELAEAMPRMAAWLDGGRRYADPDLTPADEPGEITPEALDQIQALLRALIDDRERLARWFGCIITEPRRGLPPEPPPLSAKQLHRRLQQGATLRRNAIPELAYVRHADGSATLFASGEAYELSPELADVAPLLTGRRPLTAETLRPWLERDDFLELLQTLIHSGILSLIP 4cug B 2.96 BS02 MN B 1 H133 D135 H196 H132 D134 H195 D0MK34 QLPETILGGLAPEEFLANYWQKRPLLIRQALPGFRSPITPEELAGLACEEGVTARLILEKGGAYPWEVRYGPFEPEDFVALPPTHWTLLVQEVDRLVPEVAALLETVRFVPNWRLDDIMVSYAPEGGTVGAHIDNYDVFLVQAWGRRRWQINHRPVEREELVPGLEVRLLAHFEPDAEWILEPGDVLYLPPRIPHYGVALEDCMTFSIGFRAPDQAELAEAMPRMAAWLDGGRRYADPDLTPADEPGEITPEALDQIQALLRALIDDRERLARWFGCIITEPRRGLPPEPPPLSAKQLHRRLQQGATLRRNAIPELAYVRHADGSATLFASGEAYELSPELADVAPLLTGRRPLTAETLRPWLERDDFLELLQTLIHSGILSLIP 4cuz A 3.10 BS01 AEW A 1 A95 F96 A97 L102 Q155 N156 Y157 M160 S197 V201 A93 F94 A95 L100 Q153 N154 Y155 M158 S195 V199 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz A 3.10 BS02 NDP A 1 G13 I14 A15 S19 I20 R40 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 G191 P192 I193 T195 S197 G11 I12 A13 S17 I18 R38 I63 D64 V65 S91 I92 A93 I118 T143 T144 Y145 K162 G189 P190 I191 T193 S195 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz B 3.10 BS01 AEW B 1 A95 F96 A97 Y147 V154 Q155 N156 Y157 M160 S197 A93 F94 A95 Y145 V152 Q153 N154 Y155 M158 S195 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz B 3.10 BS02 NDP B 1 G13 I14 A15 S19 I20 R40 I65 D66 V67 S93 I94 A95 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 G11 I12 A13 S17 I18 R38 I63 D64 V65 S91 I92 A93 T143 T144 Y145 K162 A188 G189 P190 I191 T193 S195 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz C 3.10 BS01 AEW C 1 A95 F96 A97 L102 Y147 V154 Q155 Y157 M160 S197 F204 A93 F94 A95 L100 Y145 V152 Q153 Y155 M158 S195 F202 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz C 3.10 BS02 NDP C 1 G13 I14 A15 S19 I20 R40 S44 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 L196 S197 G11 I12 A13 S17 I18 R38 S42 I63 D64 V65 S91 I92 A93 I118 T143 T144 Y145 K162 A188 G189 P190 I191 T193 L194 S195 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz D 3.10 BS01 AEW D 1 A95 F96 A97 L102 Y147 Q155 N156 Y157 M160 S197 F204 A93 F94 A95 L100 Y145 Q153 N154 Y155 M158 S195 F202 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz D 3.10 BS02 NDP D 1 G13 I14 A15 S19 I20 R40 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 G191 P192 I193 T195 S197 G11 I12 A13 S17 I18 R38 I63 D64 V65 S91 I92 A93 I118 T143 T144 Y145 K162 G189 P190 I191 T193 S195 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz E 3.10 BS01 AEW E 1 A95 F96 A97 L102 Y147 Q155 N156 Y157 M160 S197 V201 A93 F94 A95 L100 Y145 Q153 N154 Y155 M158 S195 V199 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz E 3.10 BS02 NDP E 1 G13 I14 A15 S19 I20 R40 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 G11 I12 A13 S17 I18 R38 I63 D64 V65 S91 I92 A93 I118 T143 T144 Y145 K162 A188 G189 P190 I191 T193 S195 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz F 3.10 BS01 AEW F 1 A95 F96 A97 L102 Y147 Q155 N156 Y157 M160 S197 V201 A93 F94 A95 L100 Y145 Q153 N154 Y155 M158 S195 V199 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz F 3.10 BS02 NDP F 1 G13 I14 A15 S19 I20 R40 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 G11 I12 A13 S17 I18 R38 I63 D64 V65 S91 I92 A93 I118 T143 T144 Y145 K162 A188 G189 P190 I191 T193 S195 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz G 3.10 BS01 AEW G 1 A95 F96 A97 Y147 Q155 N156 Y157 M160 S197 V201 A94 F95 A96 Y146 Q154 N155 Y156 M159 S196 V200 1.3.1.10 Q7A6D8 VNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz G 3.10 BS02 NDP G 1 G13 I14 A15 S19 I20 R40 S44 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 L196 S197 G12 I13 A14 S18 I19 R39 S43 I64 D65 V66 S92 I93 A94 I119 T144 T145 Y146 K163 A189 G190 P191 I192 T194 L195 S196 1.3.1.10 Q7A6D8 VNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cuz H 3.10 BS01 NDP H 1 G13 I14 A15 S19 I20 R40 I65 D66 V67 S93 I94 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 G11 I12 A13 S17 I18 R38 I63 D64 V65 S91 I92 I115 T140 T141 Y142 K159 A185 G186 P187 I188 T190 S192 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSINMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv0 A 2.20 BS01 NDP A 1 G13 I14 A15 S19 I20 R40 K41 S44 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 P192 I193 T195 S197 G11 I12 A13 S17 I18 R38 K39 S42 I63 D64 V65 S91 I92 A93 I118 T143 T144 Y145 K162 A188 P190 I191 T193 S195 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv0 A 2.20 BS02 PT6 A 1 A95 F96 A97 Y147 V154 Q155 Y157 M160 S197 F204 I207 A93 F94 A95 Y145 V152 Q153 Y155 M158 S195 F202 I205 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv0 B 2.20 BS01 NDP B 1 G13 I14 A15 S19 I20 R40 K41 S44 I65 D66 V67 S93 I94 A95 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 G12 I13 A14 S18 I19 R39 K40 S43 I64 D65 V66 S92 I93 A94 T144 T145 Y146 K163 A189 G190 P191 I192 T194 S196 1.3.1.10 Q7A6D8 VNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv0 B 2.20 BS02 PT6 B 1 A95 F96 A97 L102 Y147 V154 Q155 Y157 M160 P192 S197 A198 V201 G202 I207 A94 F95 A96 L101 Y146 V153 Q154 Y156 M159 P191 S196 A197 V200 G201 I206 1.3.1.10 Q7A6D8 VNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv0 C 2.20 BS01 NDP C 1 G13 I14 A15 S19 I20 R40 K41 S44 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 L196 S197 F204 G11 I12 A13 S17 I18 R38 K39 S42 I63 D64 V65 S91 I92 A93 I118 T143 T144 Y145 K162 A188 G189 P190 I191 T193 L194 S195 F202 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv0 C 2.20 BS02 PT6 C 1 A95 F96 A97 M99 L102 Y147 V154 Q155 Y157 M160 S197 V201 G202 G203 F204 I207 A93 F94 A95 M97 L100 Y145 V152 Q153 Y155 M158 S195 V199 G200 G201 F202 I205 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv0 D 2.20 BS01 NDP D 1 G13 I14 A15 S19 I20 R40 K41 S44 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 P192 I193 T195 S197 G11 I12 A13 S17 I18 R38 K39 S42 I63 D64 V65 S91 I92 A93 I118 T143 T144 Y145 K162 A188 P190 I191 T193 S195 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv0 D 2.20 BS02 PT6 D 1 A95 F96 A97 L102 Y147 Q155 Y157 M160 S197 V201 F204 I207 A93 F94 A95 L100 Y145 Q153 Y155 M158 S195 V199 F202 I205 1.3.1.10 Q7A6D8 NLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 A 1.95 BS01 NDP A 1 G13 I14 A15 S19 I20 R40 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 G19 I20 A21 S25 I26 R46 I71 D72 V73 S99 I100 A101 I126 T151 T152 Y153 K170 A196 G197 P198 I199 T201 S203 1.3.1.10 Q7A6D8 LYFQGAMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 A 1.95 BS02 PT6 A 1 A95 F96 A97 L102 Y147 V154 Q155 Y157 M160 S197 V201 G202 F204 I207 A101 F102 A103 L108 Y153 V160 Q161 Y163 M166 S203 V207 G208 F210 I213 1.3.1.10 Q7A6D8 LYFQGAMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 B 1.95 BS01 NDP B 1 G13 I14 A15 S19 I20 R40 K41 S44 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 L196 S197 G13 I14 A15 S19 I20 R40 K41 S44 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 L196 S197 1.3.1.10 Q7A6D8 MVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 B 1.95 BS02 PT6 B 1 A95 F96 A97 M99 L102 Y147 V154 Q155 Y157 M160 S197 A198 V201 F204 I207 A95 F96 A97 M99 L102 Y147 V154 Q155 Y157 M160 S197 A198 V201 F204 I207 1.3.1.10 Q7A6D8 MVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 C 1.95 BS01 NDP C 1 G13 I14 A15 S19 I20 R40 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 G19 I20 A21 S25 I26 R46 I71 D72 V73 S99 I100 A101 I126 T151 T152 Y153 K170 A196 G197 P198 I199 T201 S203 1.3.1.10 Q7A6D8 LYFQGAMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 C 1.95 BS02 PT6 C 1 A95 F96 A97 Y147 V154 Q155 Y157 M160 S197 V201 F204 I207 A101 F102 A103 Y153 V160 Q161 Y163 M166 S203 V207 F210 I213 1.3.1.10 Q7A6D8 LYFQGAMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 D 1.95 BS01 NDP D 1 G13 I14 A15 S19 I20 R40 K41 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 G13 I14 A15 S19 I20 R40 K41 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 1.3.1.10 Q7A6D8 MVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 D 1.95 BS02 PT6 D 1 A95 F96 A97 M99 L102 Y147 V154 Q155 Y157 M160 S197 F204 I207 A95 F96 A97 M99 L102 Y147 V154 Q155 Y157 M160 S197 F204 I207 1.3.1.10 Q7A6D8 MVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 E 1.95 BS01 NDP E 1 G13 I14 A15 S19 I20 R40 K41 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 G13 I14 A15 S19 I20 R40 K41 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 1.3.1.10 Q7A6D8 MVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 E 1.95 BS02 PT6 E 1 A95 F96 A97 M99 Y147 V154 Q155 Y157 M160 S197 V201 F204 A95 F96 A97 M99 Y147 V154 Q155 Y157 M160 S197 V201 F204 1.3.1.10 Q7A6D8 MVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 F 1.95 BS01 NDP F 1 G13 I14 A15 S19 I20 R40 K41 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 G191 P192 I193 T195 S197 F204 G19 I20 A21 S25 I26 R46 K47 I71 D72 V73 S99 I100 A101 I126 T151 T152 Y153 K170 A196 G197 P198 I199 T201 S203 F210 1.3.1.10 Q7A6D8 LYFQGAMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 F 1.95 BS02 PT6 F 1 A95 F96 A97 L102 Y147 V154 Q155 Y157 M160 S197 A198 V201 G202 G203 F204 I207 A101 F102 A103 L108 Y153 V160 Q161 Y163 M166 S203 A204 V207 G208 G209 F210 I213 1.3.1.10 Q7A6D8 LYFQGAMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 G 1.95 BS01 NDP G 1 G13 I14 A15 S19 I20 R40 K41 S44 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 P192 I193 T195 S197 G14 I15 A16 S20 I21 R41 K42 S45 I66 D67 V68 S94 I95 A96 I121 T146 T147 Y148 K165 A191 P193 I194 T196 S198 1.3.1.10 Q7A6D8 AMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 G 1.95 BS02 PT6 G 1 A95 F96 A97 M99 L102 Y147 Q155 Y157 M160 S197 V201 G202 F204 I207 A96 F97 A98 M100 L103 Y148 Q156 Y158 M161 S198 V202 G203 F205 I208 1.3.1.10 Q7A6D8 AMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 H 1.95 BS01 NDP H 1 G13 I14 A15 S19 I20 R40 K41 I65 D66 V67 S93 I94 A95 I120 T145 T146 Y147 K164 A190 P192 I193 T195 S197 G20 I21 A22 S26 I27 R47 K48 I72 D73 V74 S100 I101 A102 I127 T152 T153 Y154 K171 A197 P199 I200 T202 S204 1.3.1.10 Q7A6D8 NLYFQGAMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv1 H 1.95 BS02 PT6 H 1 A95 F96 A97 L102 Y147 Q155 Y157 M160 S197 A198 V201 G202 F204 I207 A102 F103 A104 L109 Y154 Q162 Y164 M167 S204 A205 V208 G209 F211 I214 1.3.1.10 Q7A6D8 NLYFQGAMVNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK 4cv2 A 1.80 BS01 NAI A 1 G13 A15 S19 I20 Q40 L44 C63 D64 V65 S91 I92 G93 I119 L144 S145 Y146 K163 A189 G190 P191 I192 G12 A14 S18 I19 Q39 L43 C62 D63 V64 S90 I91 G92 I118 L143 S144 Y145 K162 A188 G189 P190 I191 1.3.1.9 C6EFU4 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 4cv2 A 1.80 BS02 PT6 A 1 G93 F94 A95 L100 Y146 I153 P154 Y156 G92 F93 A94 L99 Y145 I152 P153 Y155 1.3.1.9 C6EFU4 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 4cv2 B 1.80 BS01 NAI B 1 G13 A15 S19 I20 Q40 C63 D64 V65 S91 I92 L144 S145 Y146 K163 A189 G190 P191 I192 G12 A14 S18 I19 Q39 C62 D63 V64 S90 I91 L143 S144 Y145 K162 A188 G189 P190 I191 1.3.1.9 C6EFU4 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 4cv2 B 1.80 BS02 PT6 B 1 G93 F94 A95 L100 Y146 I153 P154 Y156 G92 F93 A94 L99 Y145 I152 P153 Y155 1.3.1.9 C6EFU4 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 4cv3 A 1.95 BS01 VT4 A 1 G93 F94 L100 Y146 Y156 G92 F93 L99 Y145 Y155 1.3.1.9 C6EFU4 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPICEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 4cv3 A 1.95 BS02 NAI A 1 G13 A15 S19 I20 Q40 L44 C63 D64 V65 S91 I92 I119 L144 S145 Y146 K163 A189 P191 I192 G12 A14 S18 I19 Q39 L43 C62 D63 V64 S90 I91 I118 L143 S144 Y145 K162 A188 P190 I191 1.3.1.9 C6EFU4 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPICEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 4cv3 B 1.95 BS01 VT4 B 1 G93 L100 Y146 I153 Y156 M159 G92 L99 Y145 I152 Y155 M158 1.3.1.9 C6EFU4 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPICEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 4cv3 B 1.95 BS02 NAI B 1 G13 A15 S19 I20 Q40 C63 D64 V65 S91 I92 G93 L144 S145 Y146 K163 A189 P191 I192 G12 A14 S18 I19 Q39 C62 D63 V64 S90 I91 G92 L143 S144 Y145 K162 A188 P190 I191 1.3.1.9 C6EFU4 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPICEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 4ibl L 1.80 BS01 BGC L 1 Q49 S52 P54 Y68 Q47 S50 P52 Y66 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS02 FUC L 1 G58 S60 G56 S58 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS03 MG L 1 E25 R28 E29 E23 R26 E27 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS04 CA L 1 E26 E29 E24 E27 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS05 RB L 1 E16 E26 E29 E14 E24 E27 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS06 MG L 2 E16 E26 E14 E24 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS07 RB L 2 E6 E7 E16 E20 E4 E5 E14 E18 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS08 CA L 2 E6 E20 E4 E18 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS09 MG L 3 E14 E19 E12 E17 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS10 CA L 3 D46 G47 Q49 D63 Q64 D44 G45 Q47 D61 Q62 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS11 RB L 3 E16 E20 Q21 C22 E26 E14 E18 Q19 C20 E24 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl L 1.80 BS12 RB L 4 C114 H115 Y118 C112 H113 Y116 3.4.21.21 P08709 AFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE 4ibl H 1.80 BS01 CA H 1 E70 D72 E75 H76 E80 E58 D60 E63 H64 E68 3.4.21.21 P08709 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP 4ibl H 1.80 BS02 RB H 1 D146 C220 A221A T221 D137 C216 A217 T218 3.4.21.21 P08709 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP 4ifg A 2.11 BS01 1E8 A 1 L57 G58 V65 A78 K80 M112 L114 E129 V130 Y131 E135 L181 I194 D195 L198 L14 G15 V22 A35 K37 M69 L71 E86 V87 Y88 E92 L138 I151 D152 L155 2.7.11.17 Q9BJF5 TAIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEASKKMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN 4ih8 A 2.88 BS01 B43 A 1 V65 A78 K80 M112 L126 E129 V130 Y131 E135 L181 I194 D195 F196 V21 A34 K36 M68 L82 E85 V86 Y87 E91 L137 I148 D149 F150 2.7.11.17 Q9BJF5 AIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKDANIRIIDFGLSTHFEASKKMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRASAVEHEVDQVLDAEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNGEVDFDEFQQMLLKLCGN 4jpz C 3.02 BS01 CA C 1 D21 D23 D25 T27 E32 D15 D17 D19 T21 E26 P62158 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 4jpz C 3.02 BS02 CA C 2 D57 D59 N61 T63 E68 D51 D53 N55 T57 E62 P62158 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 4jpz C 3.02 BS03 CA C 3 D94 D96 N98 Y100 D88 D90 N92 Y94 P62158 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 4jpz C 3.02 BS04 CA C 4 D130 D132 D134 Q136 D124 D126 D128 Q130 P62158 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 4jpz I 3.02 BS01 CA I 1 D21 K22 D23 D25 T27 E32 D15 K16 D17 D19 T21 E26 P62158 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 4jpz I 3.02 BS02 CA I 2 D57 D59 N61 T63 E68 D51 D53 N55 T57 E62 P62158 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 4jpz I 3.02 BS03 CA I 3 D94 D96 N98 Y100 D88 D90 N92 Y94 P62158 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 4jpz I 3.02 BS04 CA I 4 D130 D132 D134 Q136 D124 D126 D128 Q130 P62158 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 4k1t A 1.60 BS01 ZN A 1 H123 E153 H125 E155 3.4.21.- Q2FXC3 GSENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDDNRNAYGVYFTPEIKKFIAENIDK 4k1t A 1.60 BS02 ZN A 2 H39 D77 H41 D79 3.4.21.- Q2FXC3 GSENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDDNRNAYGVYFTPEIKKFIAENIDK 4k1t B 1.60 BS01 ZN B 1 H123 E153 H125 E155 3.4.21.- Q2FXC3 GSENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDDNRNAYGVYFTPEIKKFIAENIDK 4k1t B 1.60 BS02 ZN B 2 H39 D77 H41 D79 3.4.21.- Q2FXC3 GSENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDDNRNAYGVYFTPEIKKFIAENIDK 4k1t C 1.60 BS01 ZN C 1 H123 E153 H125 E155 3.4.21.- Q2FXC3 GSENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDDDNRNAYGVYFTPEIKKFIAENIDK 4k1t C 1.60 BS02 ZN C 2 H39 D77 H41 D79 3.4.21.- Q2FXC3 GSENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDDDNRNAYGVYFTPEIKKFIAENIDK 4k6r A 1.98 BS01 ATP A 1 A14 G15 P16 G17 T18 R19 G57 H58 Q83 R85 P86 G88 A92 E207 A9 G10 P11 G12 T13 R14 G52 H53 Q78 R80 P81 G83 A87 E202 2.7.7.23,2.3.1.157 P96382 DTAVLVLAAGPGTRMRSDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAPLVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLADLIATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMAIVEQTDATPSQREIREVNAGVYAFDIAALRSALSRLSSNNAQQELYLTDVIAILRSDGQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVAAHQLAGVTVVDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNSTIGTGTKVPHLTYVGDADIGEYSNIGASSVFVNYDGTSKRRTTVGSHVRTGSDTMFVAPVTIGDGAYTGAGTVVREDVPPGALAVSAGPQRNIENWVQRKRPGSPAAQAS 4k6r A 1.98 BS02 GN1 A 1 T89 Y150 G151 E166 N181 A182 Y209 T211 N239 T84 Y145 G146 E161 N176 A177 Y204 T206 N234 2.7.7.23,2.3.1.157 P96382 DTAVLVLAAGPGTRMRSDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAPLVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLADLIATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMAIVEQTDATPSQREIREVNAGVYAFDIAALRSALSRLSSNNAQQELYLTDVIAILRSDGQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVAAHQLAGVTVVDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNSTIGTGTKVPHLTYVGDADIGEYSNIGASSVFVNYDGTSKRRTTVGSHVRTGSDTMFVAPVTIGDGAYTGAGTVVREDVPPGALAVSAGPQRNIENWVQRKRPGSPAAQAS 4k6r A 1.98 BS03 MG A 1 D114 N239 D109 N234 2.7.7.23,2.3.1.157 P96382 DTAVLVLAAGPGTRMRSDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAPLVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLADLIATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMAIVEQTDATPSQREIREVNAGVYAFDIAALRSALSRLSSNNAQQELYLTDVIAILRSDGQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVAAHQLAGVTVVDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNSTIGTGTKVPHLTYVGDADIGEYSNIGASSVFVNYDGTSKRRTTVGSHVRTGSDTMFVAPVTIGDGAYTGAGTVVREDVPPGALAVSAGPQRNIENWVQRKRPGSPAAQAS 4k6r A 1.98 BS04 GN1 A 2 R344 K362 Y377 V394 N397 Y398 K403 R339 K357 Y372 V389 N392 Y393 K398 2.7.7.23,2.3.1.157 P96382 DTAVLVLAAGPGTRMRSDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAPLVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLADLIATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMAIVEQTDATPSQREIREVNAGVYAFDIAALRSALSRLSSNNAQQELYLTDVIAILRSDGQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVAAHQLAGVTVVDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNSTIGTGTKVPHLTYVGDADIGEYSNIGASSVFVNYDGTSKRRTTVGSHVRTGSDTMFVAPVTIGDGAYTGAGTVVREDVPPGALAVSAGPQRNIENWVQRKRPGSPAAQAS 4k7a A 2.44 BS01 DHT A 1 L701 L704 N705 L707 Q711 M742 M745 R752 F764 M780 T877 L32 L35 N36 L38 Q42 M73 M76 R83 F95 M111 T201 P10275 QPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSAMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIASCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT 4k7a A 2.44 BS02 MXD A 1 E793 W796 K861 E124 W127 K185 P10275 QPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSAMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIASCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT 4kzt A 2.80 BS01 ARG A 1 Y28 K206 S225 S265 E277 L278 T280 H281 A282 G283 G285 T286 L287 G365 Y20 K198 S217 S257 E269 L270 T272 H273 A274 G275 G277 T278 L279 G357 2.3.1.1,2.7.2.8 Q0ASS9 23850694 RQTIVQLLSHMRDGKEIREYLHRFSGIDQERFAVIKVGGAVIQDDLPGLASALAFLQTVGLTPVVVHGGGPQLDAALEAADIPTERVDGLRVTRDEAMPIIRDTLTQANLALVDAIRDAGGRAAAVPRGVFEADIVDADKLGRVGEPRHIHLDLVGSAARAGQAAILACLGETPDGTLVNINADVAVRALVHALQPYKVVFLTGTGGLLDEDGDILSSINLATDFGDLMQADWVNGGMRLKLEEIKRLLDDLPLSSSVSITRPSELARELFTHAGSGTLIRRGERMVATDDKSSLDLGRLDNLVKAAFGRPAVEGYWDRLRVDRAFVTESYRAAAITTRLDGWVYLDKFAVLDDARGEGLGRTVWNRMVDYAPQLIWRSRTNNPVNGFYFEECDGAVRRDEWTVFWRGEMGPVEVADVVEKAFALPPTLEA 4kzt B 2.80 BS01 ARG B 1 Y28 K206 S225 E277 L278 T280 H281 A282 G283 G285 T286 L287 G365 Y20 K198 S217 E269 L270 T272 H273 A274 G275 G277 T278 L279 G357 2.3.1.1,2.7.2.8 Q0ASS9 23850694 RQTIVQLLSHMRDGKEIREYLHRFSGIDQERFAVIKVGGAVIQDDLPGLASALAFLQTVGLTPVVVHGGGPQLDAALEAADIPTERVDGLRVTRDEAMPIIRDTLTQANLALVDAIRDAGGRAAAVPRGVFEADIVDADKLGRVGEPRHIHLDLVGSAARAGQAAILACLGETPDGTLVNINADVAVRALVHALQPYKVVFLTGTGGLLDEDGDILSSINLATDFGDLMQADWVNGGMRLKLEEIKRLLDDLPLSSSVSITRPSELARELFTHAGSGTLIRRGERMVATDDKSSLDLGRLDNLVKAAFGRPAVEGYWDRLRVDRAFVTESYRAAAITTRLDGWVYLDKFAVLDDARGEGLGRTVWNRMVDYAPQLIWRSRTNNPVNGFYFEECDGAVRRDEWTVFWRGEMGPVEVADVVEKAFALPPTLEA 4kzt X 2.80 BS01 ARG X 1 Y28 K206 S225 E277 L278 T280 H281 A282 G283 G285 T286 L287 G365 Y20 K198 S217 E269 L270 T272 H273 A274 G275 G277 T278 L279 G357 2.3.1.1,2.7.2.8 Q0ASS9 23850694 RQTIVQLLSHMRDGKEIREYLHRFSGIDQERFAVIKVGGAVIQDDLPGLASALAFLQTVGLTPVVVHGGGPQLDAALEAADIPTERVDGLRVTRDEAMPIIRDTLTQANLALVDAIRDAGGRAAAVPRGVFEADIVDADKLGRVGEPRHIHLDLVGSAARAGQAAILACLGETPDGTLVNINADVAVRALVHALQPYKVVFLTGTGGLLDEDGDILSSINLATDFGDLMQADWVNGGMRLKLEEIKRLLDDLPLSSSVSITRPSELARELFTHAGSGTLIRRGERMVATDDKSSLDLGRLDNLVKAAFGRPAVEGYWDRLRVDRAFVTESYRAAAITTRLDGWVYLDKFAVLDDARGEGLGRTVWNRMVDYAPQLIWRSRTNNPVNGFYFEECDGAVRRDEWTVFWRGEMGPVEVADVVEKAFALPPTLEA 4kzt Y 2.80 BS01 ARG Y 1 Y28 K206 S225 S265 E277 L278 T280 H281 A282 G283 G285 T286 L287 G365 Y20 K198 S217 S257 E269 L270 T272 H273 A274 G275 G277 T278 L279 G357 2.3.1.1,2.7.2.8 Q0ASS9 23850694 RQTIVQLLSHMRDGKEIREYLHRFSGIDQERFAVIKVGGAVIQDDLPGLASALAFLQTVGLTPVVVHGGGPQLDAALEAADIPTERVDGLRVTRDEAMPIIRDTLTQANLALVDAIRDAGGRAAAVPRGVFEADIVDADKLGRVGEPRHIHLDLVGSAARAGQAAILACLGETPDGTLVNINADVAVRALVHALQPYKVVFLTGTGGLLDEDGDILSSINLATDFGDLMQADWVNGGMRLKLEEIKRLLDDLPLSSSVSITRPSELARELFTHAGSGTLIRRGERMVATDDKSSLDLGRLDNLVKAAFGRPAVEGYWDRLRVDRAFVTESYRAAAITTRLDGWVYLDKFAVLDDARGEGLGRTVWNRMVDYAPQLIWRSRTNNPVNGFYFEECDGAVRRDEWTVFWRGEMGPVEVADVVEKAFALPPTLEA 4l1o A 2.30 BS01 1VL A 1 Y65 N114 Y115 N118 L119 E209 M237 T242 C243 I391 I394 T395 F401 Y412 H413 Y65 N114 Y115 N118 L119 E209 M237 T242 C243 I391 I394 T395 F401 Y412 H413 1.2.1.5 P30838 SKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPA 4l1o B 2.30 BS01 1VL B 1 N114 Y115 N118 L119 E209 M237 T242 C243 I391 I394 T395 F401 Y412 H413 N114 Y115 N118 L119 E209 M237 T242 C243 I391 I394 T395 F401 Y412 H413 1.2.1.5 P30838 SKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH 4l1w A 2.20 BS01 NAP A 1 G22 T23 Y24 D50 Y55 K84 H117 S166 N167 Q190 Y216 S217 A218 L219 G220 S221 H222 L236 A253 L268 K270 S271 Y272 R276 Q279 N280 G24 T25 Y26 D52 Y57 K86 H119 S168 N169 Q192 Y218 S219 A220 L221 G222 S223 H224 L238 A255 L270 K272 S273 Y274 R278 Q281 N282 1.3.1.20,1.1.1.213 P52895 24434280 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1w A 2.20 BS02 STR A 1 Y24 Y55 V128 I129 H222 W227 L306 L308 Y26 Y57 V130 I131 H224 W229 L308 L310 1.3.1.20,1.1.1.213 P52895 24434280 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1w B 2.20 BS01 NAP B 1 G22 T23 Y24 D50 Y55 K84 H117 S166 N167 Q190 Y216 S217 A218 L219 S221 H222 A253 L268 K270 S271 Y272 R276 Q279 N280 G24 T25 Y26 D52 Y57 K86 H119 S168 N169 Q192 Y218 S219 A220 L221 S223 H224 A255 L270 K272 S273 Y274 R278 Q281 N282 1.3.1.20,1.1.1.213 P52895 24434280 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1w B 2.20 BS02 STR B 1 Y24 V54 V128 I129 W227 L308 Y26 V56 V130 I131 W229 L310 1.3.1.20,1.1.1.213 P52895 24434280 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1x A 2.00 BS01 NAP A 1 G22 T23 Y24 D50 Y55 K84 H117 S166 N167 Q190 Y216 S217 A218 L219 S221 H222 L236 A253 L268 K270 S271 Y272 R276 Q279 N280 G24 T25 Y26 D52 Y57 K86 H119 S168 N169 Q192 Y218 S219 A220 L221 S223 H224 L238 A255 L270 K272 S273 Y274 R278 Q281 N282 1.3.1.20,1.1.1.213 P52895 24434280 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1x A 2.00 BS02 STR A 1 Y24 L54 Y55 V128 H222 W227 L308 Y26 L56 Y57 V130 H224 W229 L310 1.3.1.20,1.1.1.213 P52895 24434280 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1x B 2.00 BS01 NAP B 1 G22 T23 Y24 D50 Y55 H117 S166 N167 Q190 Y216 S217 A218 L219 S221 H222 A253 L268 K270 S271 Y272 R276 Q279 N280 G24 T25 Y26 D52 Y57 H119 S168 N169 Q192 Y218 S219 A220 L221 S223 H224 A255 L270 K272 S273 Y274 R278 Q281 N282 1.3.1.20,1.1.1.213 P52895 24434280 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4l1x B 2.00 BS02 STR B 1 Y24 Y55 V128 I129 H222 W227 L308 Y26 Y57 V130 I131 H224 W229 L310 1.3.1.20,1.1.1.213 P52895 24434280 SVDDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 4ll3 A 1.95 BS01 017 A 1 D25 G27 A28 D30 V32 G48 G49 P81 I84 D25 G27 A28 D30 V32 G48 G49 P81 I84 Q9WFL7 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 4ll3 A 1.95 BS02 017 A 2 L23 D25 G27 A28 D29 D30 G48 G49 I50 L23 D25 G27 A28 D29 D30 G48 G49 I50 Q9WFL7 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 4ll3 B 1.95 BS01 017 A 1 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 Q9WFL7 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 4ll3 B 1.95 BS02 017 A 3 D25 G27 A28 D30 V32 G48 G49 P81 V82 I84 D25 G27 A28 D30 V32 G48 G49 P81 V82 I84 Q9WFL7 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 4lmh A 2.70 BS01 HEC A 1 A227 C228 C231 H232 L237 L239 I273 I276 H277 Y308 V311 Y313 P314 Q315 C324 L620 G624 V625 Q626 S627 T629 A185 C186 C189 H190 L195 L197 I231 I234 H235 Y266 V269 Y271 P272 Q273 C282 L578 G582 V583 Q584 S585 T587 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS02 HEC A 2 Q142 V145 L239 H240 R244 N249 C250 C253 H254 D260 I267 M272 I276 I298 I299 G300 Y308 Q100 V103 L197 H198 R202 N207 C208 C211 H212 D218 I225 M230 I234 I256 I257 G258 Y266 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS03 HEC A 3 R220 V222 F269 T270 I273 H274 H277 Y313 C321 C324 H325 L337 F338 S343 A346 H384 R178 V180 F227 T228 I231 H232 H235 Y271 C279 C282 H283 L295 F296 S301 A304 H342 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS04 HEC A 4 H274 K278 A318 A346 C347 C350 H351 H368 A380 R383 H384 V387 H232 K236 A276 A304 C305 C308 H309 H326 A338 R341 H342 V345 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS05 HEC A 5 C347 H351 E353 P355 H359 S361 T362 D363 C364 C367 H368 Y374 T377 R383 Y517 C305 H309 E311 P313 H317 S319 T320 D321 C322 C325 H326 Y332 T335 R341 Y475 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS06 HEC A 6 H312 P314 K316 I561 K565 C566 C569 H570 I574 V575 F608 S615 G617 H618 V630 T637 C638 H270 P272 K274 I519 K523 C524 C527 H528 I532 V533 F566 S573 G575 H576 V588 T595 C596 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS07 HEC A 7 Y442 Y460 I574 V575 H576 Y577 D578 C583 C586 H587 K591 T606 K611 Y400 Y418 I532 V533 H534 Y535 D536 C541 C544 H545 K549 T564 K569 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS08 HEC A 8 R557 R558 I560 I561 Q584 F608 A609 A612 H613 H618 K632 T633 D634 C635 T637 C638 H639 I650 L652 R654 R658 A680 H733 R515 R516 I518 I519 Q542 F566 A567 A570 H571 H576 K590 T591 D592 C593 T595 C596 H597 I608 L610 R612 R616 A638 H691 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS09 HEC A 9 H613 K632 A680 C681 S683 C684 H685 Y688 H724 L729 A732 H733 H571 K590 A638 C639 S641 C642 H643 Y646 H682 L687 A690 H691 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS10 HEC A 10 A678 A693 H696 I697 N700 S719 C720 C723 H724 A636 A651 H654 I655 N658 S677 C678 C681 H682 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh A 2.70 BS11 CA A 1 D260 E262 I299 G300 D218 E220 I257 G258 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh B 2.70 BS01 HEC B 1 A227 C228 C231 H232 L237 I273 H277 Y308 V311 Y313 P314 Q315 C324 L620 G624 V625 Q626 S627 T629 A185 C186 C189 H190 L195 I231 H235 Y266 V269 Y271 P272 Q273 C282 L578 G582 V583 Q584 S585 T587 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS02 HEC B 2 Q142 L239 H240 R244 N249 C250 C253 H254 D260 I267 M272 I298 I299 G300 I306 Y308 Q100 L197 H198 R202 N207 C208 C211 H212 D218 I225 M230 I256 I257 G258 I264 Y266 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS03 HEC B 3 R220 V222 F269 T270 I273 H274 H277 Y313 C321 C324 H325 L337 F338 S343 H384 R178 V180 F227 T228 I231 H232 H235 Y271 C279 C282 H283 L295 F296 S301 H342 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS04 HEC B 4 H274 K278 A318 A346 C347 C350 H351 H368 A380 R383 H384 V387 H232 K236 A276 A304 C305 C308 H309 H326 A338 R341 H342 V345 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS05 HEC B 5 C347 H351 T352 E353 P355 H359 S361 T362 D363 C364 C367 H368 Y374 T377 R383 Y517 C305 H309 T310 E311 P313 H317 S319 T320 D321 C322 C325 H326 Y332 T335 R341 Y475 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS06 HEC B 6 H312 P314 K316 K565 C566 C569 H570 I574 V575 F608 S615 G617 H618 V630 T637 C638 H270 P272 K274 K523 C524 C527 H528 I532 V533 F566 S573 G575 H576 V588 T595 C596 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS07 HEC B 7 Y442 Y460 V575 H576 Y577 C583 C586 H587 K591 K594 T606 K611 Y400 Y418 V533 H534 Y535 C541 C544 H545 K549 K552 T564 K569 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS08 HEC B 8 R557 R558 I560 I561 Q584 F608 A609 A612 H613 H618 K632 T633 D634 C635 T637 C638 H639 I650 L652 R654 R658 A680 H733 R515 R516 I518 I519 Q542 F566 A567 A570 H571 H576 K590 T591 D592 C593 T595 C596 H597 I608 L610 R612 R616 A638 H691 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS09 HEC B 9 H613 K632 T633 L652 A680 C681 C684 H685 H724 L729 H733 H571 K590 T591 L610 A638 C639 C642 H643 H682 L687 H691 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS10 HEC B 10 A678 A693 H696 I697 N700 G702 S719 C720 C723 H724 A636 A651 H654 I655 N658 G660 S677 C678 C681 H682 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh B 2.70 BS11 CA B 1 D260 E262 I299 D218 E220 I257 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNK 4lmh C 2.70 BS01 HEC C 1 C228 C231 H232 L237 I273 I276 H277 Y308 V311 Y313 P314 Q315 A323 C324 L620 G624 V625 Q626 S627 T629 C185 C188 H189 L194 I230 I233 H234 Y265 V268 Y270 P271 Q272 A280 C281 L577 G581 V582 Q583 S584 T586 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS02 HEC C 2 Q142 V145 L239 H240 R244 N249 C250 C253 H254 D260 I267 M272 I276 I298 I299 G300 I306 Y308 Q99 V102 L196 H197 R201 N206 C207 C210 H211 D217 I224 M229 I233 I255 I256 G257 I263 Y265 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS03 HEC C 3 R220 V222 F269 T270 I273 H274 H277 Y313 C321 C324 H325 L337 F338 S343 A346 H384 R177 V179 F226 T227 I230 H231 H234 Y270 C278 C281 H282 L294 F295 S300 A303 H341 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS04 HEC C 4 H274 K278 A318 A346 C347 C350 H351 H368 A380 R383 H384 V387 H231 K235 A275 A303 C304 C307 H308 H325 A337 R340 H341 V344 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS05 HEC C 5 C347 H351 E353 P355 H359 S361 T362 D363 C364 C367 H368 Y374 T377 R383 G516 Y517 C304 H308 E310 P312 H316 S318 T319 D320 C321 C324 H325 Y331 T334 R340 G473 Y474 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS06 HEC C 6 C231 H312 P314 K316 K565 C566 C569 H570 I574 V575 F608 S615 G617 H618 V630 T637 C638 C188 H269 P271 K273 K522 C523 C526 H527 I531 V532 F565 S572 G574 H575 V587 T594 C595 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS07 HEC C 7 Y442 Y460 V575 H576 Y577 C583 C586 H587 K591 K594 T606 K611 Y399 Y417 V532 H533 Y534 C540 C543 H544 K548 K551 T563 K568 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS08 HEC C 8 R557 R558 I560 I561 F608 A609 A612 H613 H618 K632 T633 C635 T637 C638 H639 I650 L652 R654 R658 A680 H733 R514 R515 I517 I518 F565 A566 A569 H570 H575 K589 T590 C592 T594 C595 H596 I607 L609 R611 R615 A637 H690 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS09 HEC C 9 H613 K632 L652 A680 C681 C684 H685 H724 L729 H733 H570 K589 L609 A637 C638 C641 H642 H681 L686 H690 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS10 HEC C 10 A678 A693 H696 I697 N700 G702 S719 C720 T722 C723 H724 A635 A650 H653 I654 N657 G659 S676 C677 T679 C680 H681 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS11 CA C 1 D260 E262 I299 G300 D217 E219 I256 G257 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh C 2.70 BS12 CA C 2 E235 S627 E192 S584 Q8EG33 GVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGN 4lmh D 2.70 BS01 HEC D 1 A227 C228 C231 H232 L237 I276 H277 Y308 V311 Y313 P314 Q315 A323 C324 L620 G624 V625 Q626 S627 T629 A185 C186 C189 H190 L195 I234 H235 Y266 V269 Y271 P272 Q273 A281 C282 L578 G582 V583 Q584 S585 T587 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS02 HEC D 2 Q142 V145 L239 H240 R244 N249 C250 C253 H254 D260 I267 M272 I276 I298 I299 G300 Y308 Q100 V103 L197 H198 R202 N207 C208 C211 H212 D218 I225 M230 I234 I256 I257 G258 Y266 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS03 HEC D 3 R220 V222 F269 T270 I273 H274 H277 Y313 C321 C324 H325 L337 F338 S343 A346 H384 R178 V180 F227 T228 I231 H232 H235 Y271 C279 C282 H283 L295 F296 S301 A304 H342 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS04 HEC D 4 H274 K278 A318 A346 C347 C350 H351 M365 H368 A380 R383 H384 V387 H232 K236 A276 A304 C305 C308 H309 M323 H326 A338 R341 H342 V345 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS05 HEC D 5 C347 H351 E353 P355 H359 S361 T362 D363 C364 C367 H368 Y374 T377 R383 G516 Y517 C305 H309 E311 P313 H317 S319 T320 D321 C322 C325 H326 Y332 T335 R341 G474 Y475 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS06 HEC D 6 C231 H312 P314 K316 I561 K565 C566 C569 H570 I574 V575 F608 S615 G617 H618 V630 T637 C638 C189 H270 P272 K274 I519 K523 C524 C527 H528 I532 V533 F566 S573 G575 H576 V588 T595 C596 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS07 HEC D 7 Y442 Y460 V575 H576 Y577 C583 C586 H587 K591 T606 K611 Y400 Y418 V533 H534 Y535 C541 C544 H545 K549 T564 K569 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS08 HEC D 8 R557 R558 I560 I561 Q584 F608 A609 A612 H613 H618 K632 T633 C635 C638 H639 I650 L652 R654 R658 A680 H733 R515 R516 I518 I519 Q542 F566 A567 A570 H571 H576 K590 T591 C593 C596 H597 I608 L610 R612 R616 A638 H691 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS09 HEC D 9 H613 K632 T633 L652 A680 C681 C684 H685 H724 L729 A732 H733 H571 K590 T591 L610 A638 C639 C642 H643 H682 L687 A690 H691 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS10 HEC D 10 A678 H696 N700 S719 C720 C723 H724 A636 H654 N658 S677 C678 C681 H682 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4lmh D 2.70 BS11 CA D 1 D260 P261 E262 I299 D218 P219 E220 I257 Q8EG33 VGVNINSTSTLKAKFTNATVDAGKVTVNFTLENANGVAVLGLTKDHDLRFGIAQLTPVKEKVGETEADRGYQWQAYINAKKEPGTVPSGVDNLNPSTQFQANVESANKCDTCLVDHGDGSYSYTYQVNVANVTEPVKVTYSADATQRATMELELPQLAANAHFDWQPSTGKTEGIQTRNVVSIQACYTCHQPESLALHGGRRIDIENCASCHTATSGDPESGNSIEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKVHYPQKPAADCAACHVEGAGAPANADLFKADLSNQACIGCHTEKPSAHHSSTDCMACHNATKPYGGTGSAAKRHGDVMKAYNDSLGYKAKFSNIGIKNNALTFDVQILDNKDQPIGKEFISDPSAYTKSSIYFSWGIDKDYPAYTAGSRYSDRGFALSNSKVSTYNEATKTFTIDSTNSNLKLPADLTGMNVELYAGVATCFNKGGYGVEDVVATPCSTDTRYAYIQDQPFRFKWNGTDTNSAAEKRRAIIDTAKCSGCHNKEIVHYDNGVNCQACHTPDKGLKTDNTYPGTKVPTSFAWKAHESEGHYLKYAGVQSGTVLKTDCATCHTADKSNVVTGIALGRSPERAWLYGDIKNNGAVIWVSSDAGACLSCHQKYLSDAAKSHIETNGGILNGTSAADVQTRASESCATCHTPSQLMEAHGNKG 4mf2 A 2.40 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 Y296 H24 S215 K216 G217 E218 T219 K220 Y257 Y282 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSEPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mf2 A 2.40 BS02 NUC P 1 S104 G105 I106 G107 P108 S109 A110 M236 R254 S94 G95 I96 G97 P98 S99 A100 M222 R240 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSEPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mf2 A 2.40 BS03 NUC D 1 K35 A38 Y39 G64 G66 T67 K68 I69 K72 K25 A28 Y29 G54 G56 T57 K58 I59 K62 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSEPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mfc A 2.13 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 Y296 H24 S214 K215 G216 E217 T218 K219 Y254 Y279 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSEKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mfc A 2.13 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 H135 R254 R258 S94 G95 G97 P98 S99 A100 H125 R237 R241 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSEKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mfc A 2.13 BS03 NUC D 1 K35 A38 Y39 G64 V65 G66 K68 I69 K72 K25 A28 Y29 G54 V55 G56 K58 I59 K62 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSEKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mfc A 2.13 BS04 0KX A 1 R149 G179 S180 R183 S188 G189 D190 Y271 F272 T273 G274 D276 N279 R139 G169 S170 R173 S178 G179 D180 Y254 F255 T256 G257 D259 N262 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSEKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mff A 2.55 BS01 NUC T 1 H34 N133 S229 K230 G231 E232 T233 K234 Y271 Y296 H24 N123 S216 K217 G218 E219 T220 K221 Y257 Y282 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mff A 2.55 BS02 NUC P 1 S104 G105 I106 G107 P108 S109 A110 R254 S94 G95 I96 G97 P98 S99 A100 R240 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mff A 2.55 BS03 NUC D 1 K35 A38 Y39 P63 G64 G66 T67 K68 I69 K25 A28 Y29 P53 G54 G56 T57 K58 I59 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mff A 2.55 BS04 MG A 1 S30 Q31 S20 Q21 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mff A 2.55 BS05 1FZ A 1 R149 G179 S180 R183 S188 G189 D190 Y271 F272 T273 G274 D276 N279 R139 G169 S170 R173 S178 G179 D180 Y257 F258 T259 G260 D262 N265 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4mlm A 1.70 BS01 FE A 1 Y24 H34 H58 D59 D161 Y23 H33 H57 D58 D160 D0E8I5 24706911 SLSNSSKVSVLISLLEKSRDLDYIGEAINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNDTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKASYLKNLSDASRKTLEYQGGPMDEGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSENQ 4mlm A 1.70 BS02 FE A 2 H58 D59 H62 H80 H104 H57 D58 H61 H79 H103 D0E8I5 24706911 SLSNSSKVSVLISLLEKSRDLDYIGEAINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNDTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKASYLKNLSDASRKTLEYQGGPMDEGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSENQ 4mlm B 1.70 BS01 FE B 1 Y24 H34 H58 D59 D161 Y23 H33 H57 D58 D159 D0E8I5 24706911 SLSNSSKVSVLISLLEKSRDLDYIGEAINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNDTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKSYLKNLSDASRKTLEYQGGPMDEGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSENQ 4mlm B 1.70 BS02 FE B 2 H58 D59 H62 H80 H104 H57 D58 H61 H79 H103 D0E8I5 24706911 SLSNSSKVSVLISLLEKSRDLDYIGEAINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNDTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKSYLKNLSDASRKTLEYQGGPMDEGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSENQ 4mln A 2.10 BS01 FE A 1 H34 H58 D59 D161 H32 H56 D57 D156 D0E8I5 24706911 LSNSSKVSVLISLLEKSRDLDYIGEAINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNDTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKYLKNLSDASRKTLEYQGGPMDGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSE 4mln A 2.10 BS02 FE A 2 H58 D59 H80 H104 H56 D57 H78 H102 D0E8I5 24706911 LSNSSKVSVLISLLEKSRDLDYIGEAINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNDTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKYLKNLSDASRKTLEYQGGPMDGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSE 4mln A 2.10 BS03 ODV A 1 E27 D59 H62 H80 H104 K108 S126 T129 Q133 R158 E25 D57 H60 H78 H102 K106 S122 T125 Q129 R153 D0E8I5 24706911 LSNSSKVSVLISLLEKSRDLDYIGEAINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNDTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKYLKNLSDASRKTLEYQGGPMDGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSE 4mln B 2.10 BS01 FE B 1 Y24 H34 H58 D59 D161 Y23 H30 H54 D55 D156 D0E8I5 24706911 SLSNSSKVSVLISLLEKSRDLDYIINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKASYLKNLSDASRKTLEYQGGPMDEGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSE 4mln B 2.10 BS02 FE B 2 H58 D59 H80 H104 H54 D55 H75 H99 D0E8I5 24706911 SLSNSSKVSVLISLLEKSRDLDYIINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKASYLKNLSDASRKTLEYQGGPMDEGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSE 4mln B 2.10 BS03 ODV B 1 Y24 D59 H62 H80 H104 V105 K108 S126 T129 Q133 R158 Y23 D55 H58 H75 H99 V100 K103 S121 T124 Q128 R153 D0E8I5 24706911 SLSNSSKVSVLISLLEKSRDLDYIINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKASYLKNLSDASRKTLEYQGGPMDEGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSE 4mrd A 2.55 BS01 BDP A 1 R45 C81 R82 I100 R21 C57 R58 I76 P15379 24606063 QIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 4mrd A 2.55 BS02 BDP A 2 Y83 I100 C101 A102 A103 Y59 I76 C77 A78 A79 P15379 24606063 QIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 4mre A 1.58 BS01 2C9 A 1 N29 V30 T31 V153 N154 R155 N6 V7 T8 V130 N131 R132 P15379 24606063 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 4mrf A 1.55 BS01 2CK A 1 N29 V30 E41 V153 N154 R155 N6 V7 E18 V130 N131 R132 P15379 24606063 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 4mrg A 1.69 BS01 24W A 1 N29 V30 T31 E41 V153 N154 R155 N6 V7 T8 E18 V130 N131 R132 P15379 24606063 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 4msx A 1.87 BS01 ZN A 1 C60 C63 H79 H85 C32 C35 H51 H57 P43589 24681967 YAYLETVVREKLDFDSEKICCITLSPLNVYCCLVCGHYYQGRHEKSPAFIHSIDENHHVFLNLTSLKFYMLPQNVQILHDGEVQLLNSIKFAAYPTYCPKDLEDFPRQCFDLSNRTYLNGFIGFTNAATYDYAHSVLLLISHMVPVRDHFLLNHFDNQGEFIKRLSICVKKIWSPKLFKHHLSVDDFVSYLKVREGLNLNPIDPRLFLLWLFNKICSSSNDLKSILNHSCKGKVKIAKSESVTGKVIVKPFWVLTLDLPEFSPFEDGNSVDDLPQINITKLLTKFTKTVFELTRLPQFLIFHFNRFDRNSDHPVKNRNQTLVEFSSELEILHVKYRLKANVVHVVIGDEKSHWITQLYDNKSEKWIEIDGINTTEREAELLFLKETFIQVWEKQE 4mva A 1.43 BS01 UVW A 1 S212 G233 G234 S212 G233 G234 5.3.1.1 C5A086 MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA 4mva B 1.43 BS01 UVW B 1 I172 S212 G233 G234 I172 S212 G233 G234 5.3.1.1 C5A086 MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQ 4mx2 A 1.90 BS01 AMP A 1 N117 H118 D119 S149 Q150 N153 Q273 R361 L363 S366 T367 R370 N94 H95 D96 S126 Q127 N130 Q250 R329 L331 S334 T335 R338 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQITEEVRQELLAITPFTYVGYT 4mx2 A 1.90 BS02 AMP B 1 R40 Y41 I331 N335 R17 Y18 I299 N303 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQITEEVRQELLAITPFTYVGYT 4mx2 B 1.90 BS01 AMP A 1 R40 Y41 I331 N335 R17 Y18 I299 N303 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKDHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 B 1.90 BS02 AMP B 1 N117 H118 D119 S149 Q150 Q273 R361 L363 S366 T367 R370 N94 H95 D96 S126 Q127 Q250 R329 L331 S334 T335 R338 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKDHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 C 1.90 BS01 AMP C 1 N117 H118 D119 S149 Q150 Q273 R361 L363 S366 T367 R370 N94 H95 D96 S126 Q127 Q250 R329 L331 S334 T335 R338 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTA 4mx2 C 1.90 BS02 AMP D 1 R40 Y41 I331 N335 R17 Y18 I299 N303 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTA 4mx2 D 1.90 BS01 AMP C 1 R40 Y41 I331 N335 R17 Y18 I301 N305 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVRAGEVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 D 1.90 BS02 AMP D 1 N117 H118 D119 S149 Q150 N153 Q273 R361 L363 S366 T367 R370 N94 H95 D96 S126 Q127 N130 Q250 R331 L333 S336 T337 R340 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVRAGEVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 E 1.90 BS01 AMP E 1 N117 H118 D119 S149 Q150 N153 Q273 R361 L363 S366 T367 R370 N94 H95 D96 S126 Q127 N130 Q250 R329 L331 S334 T335 R338 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQLITEEVRQELLAITPFTYVGYT 4mx2 E 1.90 BS02 AMP F 1 R40 Y41 I331 N335 R17 Y18 I299 N303 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQLITEEVRQELLAITPFTYVGYT 4mx2 F 1.90 BS01 AMP E 1 R40 Y41 I331 N335 R17 Y18 I299 N303 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 F 1.90 BS02 AMP F 1 N117 H118 D119 S149 Q150 N153 Q273 R361 L363 S366 T367 R370 N94 H95 D96 S126 Q127 N130 Q250 R329 L331 S334 T335 R338 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 G 1.90 BS01 AMP G 1 N117 H118 D119 S149 Q150 Q273 R361 L363 S366 T367 R370 N94 H95 D96 S126 Q127 Q250 R329 L331 S334 T335 R338 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTA 4mx2 G 1.90 BS02 AMP H 1 R40 Y41 I331 N335 R17 Y18 I299 N303 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGHVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTA 4mx2 H 1.90 BS01 AMP G 1 R40 Y41 I331 N335 R17 Y18 I299 N303 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKDVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4mx2 H 1.90 BS02 AMP H 1 N117 H118 D119 S149 Q150 Q273 R361 L363 S366 T367 R370 N94 H95 D96 S126 Q127 Q250 R329 L331 S334 T335 R338 A7LBL3 EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKPYEALKDVTEETVHRFVQQLITEEVRQELLAITPFTYVGYTAHP 4n0i A 2.00 BS01 GLN A 1 G101 G103 S104 S130 T151 G152 G153 S154 Y182 Y285 Y286 R334 D418 G87 G89 S90 S116 T137 G138 G139 S140 Y168 Y271 Y272 R320 D404 6.3.5.- Q03557 24692665 SLKESIERLSSFQSKYNIFTSINPSPYSTLTGCVASIKDNIVTKDFPTTCASHILENFKSPFDATVVKLLKQAGVHILGKTNLDEFGMGSGGVHSIRGPVINPLYPHEDKKIMGGSSSGAAASVACDLVDFALGTDTGGSVRLPACYGSVLGFKPSYGRLSRFGVIAYSQSLDTVGILSKKINVLRKVFHTLDKYDMKDPTSLSVELRELIEGNKKVRRPLKVGIVKEFSHESMPIGFHRLYLSLLEKLINLGLEIYPVSIPSVKNCLPIYYTLSPAEAASNLSRYDGIRYGYRDSELDIKDGILFAPTRSKFGTEVKNRIILGNYNLCSDAFKNNFIKAEKLRVNLIDEFDGIFRFPNVLTNSKGNPDGLDLLIVPTSSKLPGSIRDFEEEEAKSPANSYINDVFTVPMSLAGLPSLSMPLKEKTPIGLQVVGQYGDDSTVLDFVESIS 4n1t A 1.60 BS01 2GD A 1 Y7 T8 L9 N33 G36 G37 F72 F74 M81 V83 W117 D119 D120 F139 Y5 T6 L7 N31 G34 G35 F70 F72 M79 V81 W115 D117 D118 F137 3.6.1.55,3.6.1.56 P36639 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 4n1u A 1.60 BS01 2GE A 1 Y7 T8 F27 N33 F72 F74 M81 W117 D119 D120 W123 F139 Y5 T6 F25 N31 F70 F72 M79 W115 D117 D118 W121 F137 3.6.1.55,3.6.1.56 P36639 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDT 4n1u B 1.60 BS01 2GE B 1 Y7 T8 F27 N33 F72 F74 M81 W117 D119 D120 W123 F139 Y6 T7 F26 N32 F71 F73 M80 W116 D118 D119 W122 F138 3.6.1.55,3.6.1.56 P36639 GASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDT 4n4s A 2.20 BS01 2H1 A 1 I29 V37 A50 K52 I54 E69 I70 L73 I82 I101 D104 M106 L154 L164 I22 V30 A43 K45 I47 E62 I63 L66 I75 I94 D97 M99 L147 L157 2.7.11.24 P63086 24704509 GPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVADLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKILDFGLARVADPDTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY 4n4s B 2.20 BS01 2H1 B 1 I29 V37 A50 K52 I54 E69 L73 I82 I101 A103 D104 M106 L154 I22 V30 A43 K45 I47 E62 L66 I75 I94 A96 D97 M99 L147 2.7.11.24 P63086 24704509 GPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVADLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKILDFGLARVADPATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY 4n5i X 2.00 BS01 2HD X 1 W15 T18 G74 G75 G76 W77 L84 S146 A147 V186 L192 M202 Y206 F245 H278 Q283 W11 T14 G70 G71 G72 W73 L80 S142 A143 V182 L188 M198 Y202 F241 H274 Q279 C7TF14 EAMLAKVQASWAQTAARDKARYADERVPEDVHWETEYRYEQSADPQQTLNLYYPAKRRNATMPTVIDIHGGGWFYGDRNLNRNYCRYLASQGYAVMGMGYRLLPDVDLRGQIQDIFASLRWLSHFGPQRGFDLDHVLLTGDSAGGHLASLVACIQQSAELQELFGVSRVNFNFTLVALVCPVAEPSKLPEAAGDMSDMAAFYLDKLSGGDQALVDHLNFSQVVKGLDLPPFMLIGGQNDSFYLQSQALLKVFDANHVTYTTKLWPASAGPHLKHVFNVQHWEWPESIETNLEMLRTFDALSKQQDQAEENE 4nef A 2.75 BS01 ZN A 1 C75 H80 C74 H79 P41181 SELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGL 4nid A 1.58 BS01 NUC B 1 T51 P52 G53 Y55 M57 W69 G75 Y76 Y78 K127 L128 C129 H131 D133 R161 R210 T40 P41 G42 Y44 M46 W58 G64 Y65 Y67 K116 L117 C118 H120 D122 R150 R199 1.14.11.33 P05050 24596302 QEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nid A 1.58 BS02 NUC C 1 R161 N162 R167 R150 N151 R156 1.14.11.33 P05050 24596302 QEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nid A 1.58 BS03 MN A 1 H131 D133 H187 H120 D122 H176 1.14.11.33 P05050 24596302 QEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nid A 1.58 BS04 AKG A 1 L118 N120 Y122 L128 H131 D133 H187 I189 R204 N206 L107 N109 Y111 L117 H120 D122 H176 I178 R193 N195 1.14.11.33 P05050 24596302 QEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nig A 1.52 BS01 NUC B 1 T51 P52 G53 Y55 M57 W69 G75 Y76 Y78 K127 L128 C129 L130 H131 D133 R161 T39 P40 G41 Y43 M45 W57 G63 Y64 Y66 K115 L116 C117 L118 H119 D121 R149 1.14.11.33 P05050 24596302 EPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKIHPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nig A 1.52 BS02 NUC C 1 R161 N162 R167 R149 N150 R155 1.14.11.33 P05050 24596302 EPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKIHPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nig A 1.52 BS03 MN A 1 H131 D133 H187 H119 D121 H175 1.14.11.33 P05050 24596302 EPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKIHPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nig A 1.52 BS04 AKG A 1 L118 N120 Y122 L128 H131 D133 H187 I189 R204 N206 L106 N108 Y110 L116 H119 D121 H175 I177 R192 N194 1.14.11.33 P05050 24596302 EPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKIHPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nih A 1.37 BS01 NUC B 1 T51 P52 G53 Y55 M57 W69 G75 Y76 Y78 K127 L128 C129 L130 H131 D133 R161 R210 T38 P39 G40 Y42 M44 W56 G62 Y63 Y65 K114 L115 C116 L117 H118 D120 R148 R197 1.14.11.33 P05050 24596302 PLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKDLPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nih A 1.37 BS02 NUC C 1 R161 N162 R167 R148 N149 R154 1.14.11.33 P05050 24596302 PLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKDLPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nih A 1.37 BS03 MN A 1 H131 D133 H187 H118 D120 H174 1.14.11.33 P05050 24596302 PLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKDLPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nih A 1.37 BS04 AKG A 1 L118 N120 Y122 L128 H131 D133 H187 I189 R204 N206 L105 N107 Y109 L115 H118 D120 H174 I176 R191 N193 1.14.11.33 P05050 24596302 PLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKDLPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nii A 1.62 BS01 NUC B 1 T51 P52 G53 Y55 M57 W69 G75 Y76 Y78 K127 L128 C129 L130 H131 D133 R210 T40 P41 G42 Y44 M46 W58 G64 Y65 Y67 K116 L117 C118 L119 H120 D122 R196 1.14.11.33 P05050 24596302 QEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKILRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nii A 1.62 BS02 NUC C 1 R161 N162 R167 R147 N148 R153 1.14.11.33 P05050 24596302 QEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKILRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nii A 1.62 BS03 MN A 1 H131 D133 H187 H120 D122 H173 1.14.11.33 P05050 24596302 QEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKILRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4nii A 1.62 BS04 AKG A 1 L118 N120 Y122 L128 H131 D133 H187 I189 R204 N206 L107 N109 Y111 L117 H120 D122 H173 I175 R190 N192 1.14.11.33 P05050 24596302 QEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLCLHQDKILRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGK 4np2 A 1.75 BS01 2L1 A 1 N29 V30 E41 G44 R82 V153 N154 R155 N6 V7 E18 G21 R59 V130 N131 R132 P15379 24606063 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 4np3 A 1.61 BS01 2L2 A 1 N29 V30 E41 G44 R82 V153 N154 R155 N6 V7 E18 G21 R59 V130 N131 R132 P15379 24606063 NQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDI 4nqc A 2.50 BS01 2LJ A 1 Y7 R9 S24 K43 H58 Y62 L66 W69 R94 I96 Y152 Q153 W156 Y8 R10 S25 K44 H59 Y63 L67 W70 R95 I97 Y153 Q154 W157 Q95460 24695216 MRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRLFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASISNLYSCHVEHSGVHMVLQV 4nqc C 2.50 BS01 2LJ C 1 Y7 R9 S24 K43 H58 Y62 L66 W69 R94 I96 Y152 Q153 W156 Y8 R10 S23 K42 H57 Y61 L65 W68 R93 I95 Y151 Q152 W155 Q95460 24695216 MRTHSLRYFRLGVSDPIVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELNLYSCHVEHSGVHMVLQV 4nqd A 2.20 BS01 2LJ A 1 Y7 R9 S24 T34 H58 Y62 L66 W69 R94 I96 Y152 Q153 W156 Y7 R9 S24 T34 H58 Y62 L66 W69 R94 I96 Y152 Q153 W156 Q95460 24695216 RTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIEIDYGDILPSGDGTYQAWASIELYSCHVEHSGVHMVLQV 4nqd C 2.20 BS01 2LJ C 1 Y7 R9 S24 T34 H58 Y62 L66 W69 R94 I96 Y152 Q153 W156 Y8 R10 S23 T33 H57 Y61 L65 W68 R93 I95 Y151 Q152 W155 Q95460 24695216 MRTHSLRYFRLGVSDPIVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRALFCKAHGFYPPEIYMTWMKNIDYGDILPSGDGTYQAWASIESNLYSCHVEHSGVHMVLQV 4nqe A 2.10 BS01 2L4 A 1 Y7 R9 S24 K43 H58 Y62 L66 W69 R94 I96 Y152 Q153 W156 Y8 R10 S25 K44 H59 Y63 L67 W70 R95 I97 Y153 Q154 W157 Q95460 24695216 MRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELLYSCHVEHSGVHMVLQV 4nqe C 2.10 BS01 2L4 C 1 Y7 R9 S24 K43 H58 Y62 L66 W69 R94 I96 Y152 Q153 W156 Y8 R10 S23 K42 H57 Y61 L65 W68 R93 I95 Y151 Q152 W155 Q95460 24695216 MRTHSLRYFRLGVSDPIVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRALFCKAHGFYPPEIYMTWMKNGEIDYGDILPSGDGTYQAWASISNLYSCHVEHSGVHMVLQV 4nxz A 2.56 BS01 NUC T 1 H34 R40 S229 K230 G231 E232 T233 K234 R258 N279 K280 R283 L287 T292 I293 N294 E295 Y296 H25 R31 S220 K221 G222 E223 T224 K225 R249 N270 K271 R274 L278 T283 I284 N285 E286 Y287 2.7.7.7,4.2.99.- P06746 24694247 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4nxz A 2.56 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 D192 R254 D256 Y271 S95 G96 G98 P99 S100 A101 D183 R245 D247 Y262 2.7.7.7,4.2.99.- P06746 24694247 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4nxz A 2.56 BS03 NUC D 1 K35 A38 Y39 P63 G64 V65 G66 T67 K68 I69 K72 K26 A29 Y30 P54 G55 V56 G57 T58 K59 I60 K63 2.7.7.7,4.2.99.- P06746 24694247 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4nxz A 2.56 BS04 MN A 1 D190 D192 D181 D183 2.7.7.7,4.2.99.- P06746 24694247 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4nxz A 2.56 BS05 MN A 2 D190 D192 D256 D181 D183 D247 2.7.7.7,4.2.99.- P06746 24694247 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4nxz A 2.56 BS06 1FZ A 1 G179 S180 R183 G189 D190 D192 Y271 G274 S275 D276 N279 G170 S171 R174 G180 D181 D183 Y262 G265 S266 D267 N270 2.7.7.7,4.2.99.- P06746 24694247 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4ny8 A 2.25 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 Y296 H24 S217 K218 G219 E220 T221 K222 Y259 Y284 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4ny8 A 2.25 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 R254 S94 G95 G97 P98 S99 A100 R242 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4ny8 A 2.25 BS03 NUC D 1 K35 A38 Y39 G64 G66 K68 I69 K72 K25 A28 Y29 G54 G56 K58 I59 K62 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4ny8 A 2.25 BS04 MN A 1 D190 D192 D180 D182 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4ny8 A 2.25 BS05 MN A 2 D190 D192 D180 D182 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4ny8 A 2.25 BS06 0KX A 1 R149 G179 S180 R183 G189 D190 D192 Y271 G274 S275 D276 N279 R139 G169 S170 R173 G179 D180 D182 Y259 G262 S263 D264 N267 2.7.7.7,4.2.99.- P06746 24694247 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4o3a A 1.80 BS01 ASP A 1 Y61 P89 L90 T91 R96 G141 S142 T143 E193 Y61 P89 L90 T91 R96 G141 S142 T143 E193 P19491 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4o3a A 1.80 BS02 ZN A 1 H23 E30 H23 E30 P19491 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4o3a A 1.80 BS03 ZN A 2 E42 H46 E42 H46 P19491 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4o3a B 1.80 BS01 ASP B 1 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 M196 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 M196 P19491 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 4o3a B 1.80 BS02 ZN B 1 E42 H46 E42 H46 P19491 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 4o3a C 1.80 BS01 ASP C 1 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y220 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y220 P19491 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG 4o3a C 1.80 BS02 ZN C 1 E42 K45 H46 E42 K45 H46 P19491 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG 4o3b B 1.91 BS01 GLU B 1 Y61 P89 L90 T91 R96 G141 S142 T143 E193 Y220 Y58 P86 L87 T88 R93 G138 S139 T140 E190 Y217 P19491 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4o3c A 1.50 BS01 ASP A 1 Y61 P89 L90 T91 R96 G141 S142 T143 E193 Y220 Y61 P89 L90 T91 R96 G141 S142 T143 E193 Y220 P19491 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECG 4o42 A 1.87 BS01 III B 1 E272 A290 Y295 W322 G324 W325 H329 T331 D408 W423 E424 D425 L428 E3 A21 Y26 W53 G55 W56 H60 T62 D139 W154 E155 D156 L159 3.6.4.12 O14646 EFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFS 4o64 A 2.13 BS01 ZN A 1 C613 C616 C619 C651 C6 C9 C12 C44 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN 4o64 A 2.13 BS02 ZN A 2 C624 C627 C630 C646 C17 C20 C23 C39 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN 4o64 A 2.13 BS03 ZN A 3 C662 C665 H696 C699 C55 C58 H89 C92 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN 4o64 A 2.13 BS04 ZN A 4 C688 C691 C719 C722 C81 C84 C112 C115 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN 4o64 B 2.13 BS01 ZN B 1 C613 C616 C619 C651 C6 C9 C12 C44 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKSEGVVNDELPNCWECPKCN 4o64 B 2.13 BS02 ZN B 2 C624 C627 C630 C646 C17 C20 C23 C39 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKSEGVVNDELPNCWECPKCN 4o64 B 2.13 BS03 ZN B 3 C662 C665 H696 C699 C55 C58 H89 C92 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKSEGVVNDELPNCWECPKCN 4o64 B 2.13 BS04 ZN B 4 C688 C691 C719 C722 C81 C84 C111 C114 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKSEGVVNDELPNCWECPKCN 4o64 C 2.13 BS01 ZN C 1 C613 C616 C619 C651 C6 C9 C12 C44 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN 4o64 C 2.13 BS02 ZN C 2 C624 C627 C630 C646 C17 C20 C23 C39 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN 4o64 C 2.13 BS03 ZN C 3 C662 C665 H696 C699 C55 C58 H89 C92 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN 4o64 C 2.13 BS04 ZN C 4 C688 C691 C719 C722 C81 C84 C112 C115 Q8NHM5 RRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN 4o7d A 2.30 BS01 ONL A 1 Y249 Q285 S286 N335 E381 N388 Y414 Y466 G483 V484 Y31 Q67 S68 N117 E163 N170 Y196 Y248 G265 V266 3.5.1.2 O94925 24451979 SMIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYD 4oct A 2.28 BS01 MN A 1 H204 D206 H266 H121 D123 H183 1.14.11.- Q6P6C2 QKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRL 4oct A 2.28 BS02 AKG A 1 N193 Y195 H204 D206 H266 I268 R277 V279 I281 N110 Y112 H121 D123 H183 I185 R194 V196 I198 1.14.11.- Q6P6C2 QKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRL 4oct B 2.28 BS01 MN B 1 H204 D206 H266 H121 D123 H183 1.14.11.- Q6P6C2 LQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLE 4oct B 2.28 BS02 AKG B 1 N193 Y195 H204 D206 L226 H266 I268 R277 V279 I281 N110 Y112 H121 D123 L143 H183 I185 R194 V196 I198 1.14.11.- Q6P6C2 LQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLE 4ojm X 1.95 BS01 TYR X 1 Y99 G101 D103 L133 D143 Y247 Q251 D254 Q267 Q273 Y68 G70 D72 L102 D112 Y208 Q212 D215 Q228 Q234 6.1.1.1 P12063 24520960 MLRREFGPKYTAKINEAEENWQARAEAIKKGKKQNTWDLFEERGYVKDTAGTKEHIAELMRTRRIGAYVGIDPTAPSLHVGHLLPLMPLFWMYLEGYKAFTLIGGSTAKIGDPTGSSSDATMNMTKIHYQLKKLWENVDTQMRARGYEADWARKRGIVNNNHWWNKQPMLEVLRRVGHALRIGPMLSRDTVKNKMTQGDGVSFAEFTYPIMQGWDWFELFYQQGVQMQIGGSDQYGNIISGLEVVKAARESEPDPQERKYVTPKTALDECVGFTVPLLTDSSGAKFGKSAGNAIWLDPYQTSVFDFYGYFVRRSDQEVENLLKLFTFMPISEITKTMEEHIKDPSKRVAQHTLAREVVTLVHGKQEASAAEDQHRMMYTGQM 4omy A 3.06 BS01 NUC E 1 V45 Q56 S57 S60 Q61 Q79 T80 I81 Y83 V40 Q51 S52 S55 Q56 Q74 T75 I76 Y78 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4omy A 3.06 BS02 NUC F 1 N28 R31 S55 S57 Q61 H62 N23 R26 S50 S52 Q56 H57 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4omy B 3.06 BS01 NUC E 1 N28 R31 L54 S57 Q61 H62 K65 R76 A78 Q79 N23 R26 L49 S52 Q56 H57 K60 R71 A73 Q74 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4omy B 3.06 BS02 NUC F 1 A44 V45 G46 Q56 S57 S60 Q61 R67 Q79 T80 I81 Y83 A39 V40 G41 Q51 S52 S55 Q56 R62 Q74 T75 I76 Y78 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4omy C 3.06 BS01 NUC G 1 N28 R31 S55 S57 Q61 H62 R76 A78 Q79 N23 R26 S50 S52 Q56 H57 R71 A73 Q74 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4omy C 3.06 BS02 NUC H 1 A44 V45 S57 S60 S64 R67 Q79 T80 I81 Y83 A39 V40 S52 S55 S59 R62 Q74 T75 I76 Y78 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4omy D 3.06 BS01 NUC G 1 V45 Q56 S57 S60 Q61 Q79 T80 I81 Y83 V40 Q51 S52 S55 Q56 Q74 T75 I76 Y78 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4omy D 3.06 BS02 NUC H 1 N28 R31 L54 S55 S57 Q61 H62 K65 N23 R26 L49 S50 S52 Q56 H57 K60 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4on0 A 3.00 BS01 NUC E 1 V45 Q56 S57 S60 Q61 Q79 T80 I81 Y83 V40 Q51 S52 S55 Q56 Q74 T75 I76 Y78 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4on0 A 3.00 BS02 NUC F 1 N28 R31 S55 S57 A58 Q61 H62 K65 N23 R26 S50 S52 A53 Q56 H57 K60 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4on0 B 3.00 BS01 NUC E 1 N28 K30 R31 S55 S57 A58 Q61 H62 R76 A78 Q79 N23 K25 R26 S50 S52 A53 Q56 H57 R71 A73 Q74 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4on0 B 3.00 BS02 NUC F 1 A44 V45 G46 Q56 S57 S60 Q61 R67 Q79 T80 I81 Y83 A39 V40 G41 Q51 S52 S55 Q56 R62 Q74 T75 I76 Y78 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4on0 C 3.00 BS01 NUC G 1 V45 Q56 S57 S60 Q61 Q79 T80 I81 Y83 V40 Q51 S52 S55 Q56 Q74 T75 I76 Y78 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4on0 C 3.00 BS02 NUC H 1 N28 R31 S55 S57 A58 Q61 H62 K65 N23 R26 S50 S52 A53 Q56 H57 K60 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4on0 D 3.00 BS01 NUC G 1 N28 K30 R31 S55 S57 A58 Q61 H62 K65 R76 A78 Q79 N23 K25 R26 S50 S52 A53 Q56 H57 K60 R71 A73 Q74 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4on0 D 3.00 BS02 NUC H 1 A44 V45 G46 Q56 S57 S60 Q61 R67 Q79 T80 I81 Y83 A39 V40 G41 Q51 S52 S55 Q56 R62 Q74 T75 I76 Y78 Q83TD2 QPLSPEKHEEAEIAAGFLSAMANPKRLLILDSLVKEEMAVGALANKVGLSQSALSQHLSKLRAQNLVSTRRDAQTIYYSSSSDSVMKILGALSEIYG 4oog A 2.50 BS01 NUC D 1 I50 Q51 H54 K58 I8 Q9 H12 K16 Q02555 24703949 NYKYLEVIQLEHAVTKLVESYNKIIELSPNLVAYNEAVNNQDRVPVQILPSLSRYQLKLAAELKTLHDLKKDAILTEITDYENEFDTEQKQPILQEISKADMEKLEKLE 4oog B 2.50 BS01 NUC D 1 H54 K58 H13 K17 Q02555 24703949 SNYKYLEVIQLEHAVTKLVESYNKIIELSPNLVAYNEAVNNQDRVPVQILPSLSRYQLKLAAELKTLHDLKKDAILTEITDYENEFDTEQKQPILQEISKADMEKLEKLE 4oog C 2.50 BS01 NUC D 1 D245 N249 E265 G266 S269 R272 M273 S277 N278 K371 R372 Q373 Y375 S376 L377 G379 Y380 A381 Y387 K392 P393 A395 R418 N419 I420 K421 R445 A446 I448 R450 S453 V454 L455 K456 D49 N53 E69 G70 S73 R76 M77 S81 N82 K175 R176 Q177 Y179 S180 L181 G183 Y184 A185 Y191 K196 P197 A199 R222 N223 I224 K225 R249 A250 I252 R254 S257 V258 L259 K260 3.1.26.3 Q02555 24703949 KWPPKLPEIQDLAIRARVFIHKSTIKDKVYLSGSEMINAHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQWSIMYNFHEKLKTNFDLKDENSNFQNGKLKLYADVFEAYIGGLMEDDPRNNLPKIRKWLRKLAKPVIEEATRNQVALEKTDKLDMNAKRQLYSLIGYASLRLHYVTVKKPTAVDPNSIVECRVGDGTVLGTGVGRNIKIAGIRAAENALRDKKMLDFYAKQRAAIPRSESVLKD 4oog C 2.50 BS02 MG C 1 D245 E320 D49 E124 3.1.26.3 Q02555 24703949 KWPPKLPEIQDLAIRARVFIHKSTIKDKVYLSGSEMINAHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQWSIMYNFHEKLKTNFDLKDENSNFQNGKLKLYADVFEAYIGGLMEDDPRNNLPKIRKWLRKLAKPVIEEATRNQVALEKTDKLDMNAKRQLYSLIGYASLRLHYVTVKKPTAVDPNSIVECRVGDGTVLGTGVGRNIKIAGIRAAENALRDKKMLDFYAKQRAAIPRSESVLKD 4oog C 2.50 BS03 MG C 2 E241 D317 E320 E45 D121 E124 3.1.26.3 Q02555 24703949 KWPPKLPEIQDLAIRARVFIHKSTIKDKVYLSGSEMINAHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQWSIMYNFHEKLKTNFDLKDENSNFQNGKLKLYADVFEAYIGGLMEDDPRNNLPKIRKWLRKLAKPVIEEATRNQVALEKTDKLDMNAKRQLYSLIGYASLRLHYVTVKKPTAVDPNSIVECRVGDGTVLGTGVGRNIKIAGIRAAENALRDKKMLDFYAKQRAAIPRSESVLKD 4oog C 2.50 BS04 MG C 3 E238 E241 E42 E45 3.1.26.3 Q02555 24703949 KWPPKLPEIQDLAIRARVFIHKSTIKDKVYLSGSEMINAHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQWSIMYNFHEKLKTNFDLKDENSNFQNGKLKLYADVFEAYIGGLMEDDPRNNLPKIRKWLRKLAKPVIEEATRNQVALEKTDKLDMNAKRQLYSLIGYASLRLHYVTVKKPTAVDPNSIVECRVGDGTVLGTGVGRNIKIAGIRAAENALRDKKMLDFYAKQRAAIPRSESVLKD 4or5 C 2.90 BS01 ZN C 1 C22 H33 C34 C37 C22 H33 C34 C37 P04608 MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYG 4or5 C 2.90 BS02 ZN C 2 C25 C27 C30 C25 C27 C30 P04608 MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYG 4or5 H 2.90 BS01 ZN H 1 C22 H33 C34 C37 C22 H33 C34 C37 P04608 MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYG 4or5 H 2.90 BS02 ZN H 2 C25 C27 C30 C25 C27 C30 P04608 MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYG 4ouc A 1.90 BS01 III B 1 G493 V494 A587 N588 E613 D649 H651 W652 G653 D707 D709 L710 G713 D714 Q718 F719 Y722 G24 V25 A118 N119 E144 D180 H182 W183 G184 D238 D240 L241 G244 D245 Q249 F250 Y253 2.7.11.1 Q8TF76 KGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 4ouc A 1.90 BS02 5ID A 1 I490 G491 E492 F495 V498 A509 F605 E606 F607 G608 G609 D611 G653 L656 I686 I21 G22 E23 F26 V29 A40 F136 E137 F138 G139 G140 D142 G184 L187 I217 2.7.11.1 Q8TF76 KGPVPFSHCLPTEKLQRCEKIGEGVFGEVFQTIADHTPVAIKIIAIEGPDLVNGSHQKTFEEILPEIIISKELSLLSGEVCNRTEGFIGLNSVHCVQGSYPPLLLKAWDHYNSTKGSANDRPDFFKDDQLFIVLEFEFGGIDLEQMRTKLSSLATAKSILHQLTASLAVAEASLRFEHRDLHWGNVLLKKTSLKKLHYTLNGKSSTIPSCGLQVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMKQIKRKIQEFHRTMLNFSSATDLLCQHSLFK 4oww B 2.30 BS01 NUC L 1 H36 V38 S53 W55 D56 Y74 F78 Y85 T86 G87 R88 H32 V34 S49 W51 D52 Y70 F74 Y81 T82 G83 R84 Q9BQ15 24630995 TFVKDIKPGLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEP 4owx B 2.30 BS01 NUC L 1 G13 K15 T32 K33 H36 W55 D56 Y74 A75 F78 Y85 T86 R88 G9 K11 T28 K29 H32 W51 D52 Y70 A71 F74 Y81 T82 R84 Q9BQ15 24630995 TFVKDIKPGLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEP 4oxx A 1.21 BS01 FMN A 1 T9 E10 T11 G12 N13 A14 A57 T58 Y59 G93 D94 Y97 T98 T99 F100 N101 T127 T9 E10 T11 G12 N13 A14 A57 T58 Y59 G93 D94 Y97 T98 T99 F100 N101 T127 Q8VQF4 24533927 MNALILYGTETGNAEACATTISQVLADTVDTKVHDLADMTPRAMLDSGADLIVFATATYGEGEFAGGGAAFFETLRETKPDLSGLRFAVFGLGDSYYTTFNQAGATAATILASLGGTQVGDTARHDTSSGDDPAATAAEWAREILTALATPAV 4ozf A 2.70 BS01 III J 1 Y9 Y22 W43 R52 F54 F58 N62 V65 L66 H68 N69 S72 L73 K75 R76 Y9 Y23 W44 R53 F54 F58 N62 V65 L66 H68 N69 S72 L73 K75 R76 P01909 IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPE 4ozf B 2.70 BS01 III J 1 F11 L26 S28 A57 Y60 W61 I67 R70 K71 A74 R77 V78 H81 N82 L85 F9 L24 S26 A55 Y58 W59 I65 R68 K69 A72 R75 V76 H79 N80 L83 Q5Y7D3 SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 4ozf H 2.70 BS01 III J 1 T37 F108 R109 A112 D114 T28 F94 R95 A98 D100 GVSQSPSNKVTEKGKDVELRCDPISGHTALYWYRQSLGQGLEFLIYFQGNSAPDKSGLPSDRFSAERTGGSVSTLTIQRTQQEDSAVYLCASSFRALAADTQYFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 4ozg A 3.00 BS01 III J 1 Y9 Y22 W43 R52 F54 F58 N62 V65 H68 N69 S72 L73 R76 Y9 Y23 W44 R53 F54 F58 N62 V65 H68 N69 S72 L73 R76 P01909 IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPE 4ozg B 3.00 BS01 III J 1 Y9 F11 G13 L26 S28 P56 A57 Y60 W61 I67 R70 K71 A74 R77 V78 H81 N82 L85 Y7 F9 G11 L24 S26 P54 A55 Y58 W59 I65 R68 K69 A72 R75 V76 H79 N80 L83 Q5Y7D3 SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 4ozg C 3.00 BS01 III I 1 Y9 Y22 R52 F54 F58 N62 V65 H68 N69 N71 S72 L73 R76 Y9 Y23 R53 F54 F58 N62 V65 H68 N69 N71 S72 L73 R76 P01909 IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEP 4ozg C 3.00 BS02 CA C 1 E85 N111 E85 N111 P01909 IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEP 4ozg D 3.00 BS01 III I 1 Y9 F11 L26 S28 P56 A57 Y60 W61 I67 R70 K71 A74 R77 V78 H81 N82 Y7 F9 L24 S26 P54 A55 Y58 W59 I65 R68 K69 A72 R75 V76 H79 N80 Q5Y7D3 SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 4ozg E 3.00 BS01 III I 1 N36 G108 N29 G91 MKTTQPPSMDCAEGRAANLPCNHSTISGNEYVYWYRQIHSQGPQYIIHGLKNNETNEMASLIITEDRKSSTLILPHATLRDTAVYYCIVLGGADGLTFGKGTHLIIQPYIQNPDPAVYQLRDSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP 4ozg F 3.00 BS01 III I 1 T37 R109 D114 T28 R95 D98 GVSQSPSNKVTEKGKDVELRCDPISGHTALYWYRQSLGQGLEFLIYFQGNSAPDKSGLPSDRFSAERTGGSVSTLTIQRTQQEDSAVYLCASSFRFTDTQYFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 4ozg H 3.00 BS01 III J 1 T37 F108 R109 T111 D114 T28 F94 R95 T97 D98 GVSQSPSNKVTEKGKDVELRCDPISGHTALYWYRQSLGQGLEFLIYFQGNSAPDKSGLPSDRFSAERTGGSVSTLTIQRTQQEDSAVYLCASSFRFTDTQYFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 4ozh A 2.80 BS01 III J 1 Y9 Y22 R52 F54 F58 N62 V65 L66 H68 N69 S72 L73 R76 Y9 Y23 R53 F54 F58 N62 V65 L66 H68 N69 S72 L73 R76 P01909 IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPE 4ozh B 2.80 BS01 III J 1 F11 S28 A57 Y60 W61 I67 R70 K71 R77 V78 N82 L85 F9 S26 A55 Y58 W59 I65 R68 K69 R75 V76 N80 L83 Q5Y7D3 SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 4ozh C 2.80 BS01 III I 1 Y9 Y22 H24 R52 F54 F58 N62 V65 H68 N69 S72 L73 R76 Y9 Y23 H25 R53 F54 F58 N62 V65 H68 N69 S72 L73 R76 P01909 IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPE 4ozh D 2.80 BS01 III I 1 Y9 F11 L26 S28 I37 P56 A57 Y60 W61 I67 R70 K71 A74 R77 V78 H81 N82 L85 Y7 F9 L24 S26 I35 P54 A55 Y58 W59 I65 R68 K69 A72 R75 V76 H79 N80 L83 Q5Y7D3 SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 4ozh E 2.80 BS01 III I 1 N36 G109 N29 G92 MKTTQPPSMDCAEGRAANLPCNHSTISGNEYVYWYRQIHSQGPQYIIHGLKNNETNEMASLIITEDRKSSTLILPHATLRDTAVYYCIVWGGATNKLIFGTGTLLAVQPNIQNPDPAVYQLRDSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP 4ozh F 2.80 BS01 III I 1 T37 V108 R109 D114 T28 V94 R95 D98 GVSQSPSNKVTEKGKDVELRCDPISGHTALYWYRQSLGQGLEFLIYFQGNSAPDKSGLPSDRFSAERTGGSVSTLTIQRTQQEDSAVYLCASSVRSTDTQYFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 4ozh G 2.80 BS01 III J 1 N36 G109 N29 G92 MKTTQPPSMDCAEGRAANLPCNHSTISGNEYVYWYRQIHSQGPQYIIHGLKNNETNEMASLIITEDRKSSTLILPHATLRDTAVYYCIVWGGATNKLIFGTGTLLAVQPNIQNPDPAVYQLRDSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP 4ozh H 2.80 BS01 III J 1 T37 V108 R109 D114 T28 V94 R95 D98 GVSQSPSNKVTEKGKDVELRCDPISGHTALYWYRQSLGQGLEFLIYFQGNSAPDKSGLPSDRFSAERTGGSVSTLTIQRTQQEDSAVYLCASSVRSTDTQYFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 4ozi A 3.20 BS01 III J 1 Y9 Y22 R52 F54 F58 N62 V65 H68 N69 S72 L73 R76 Y9 Y23 R53 F54 F58 N62 V65 H68 N69 S72 L73 R76 P01909 IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPE 4ozi B 3.20 BS01 III J 1 Y9 F11 G13 L26 S28 S30 F47 L53 P56 A57 Y60 W61 I67 K71 R77 V78 H81 N82 L85 Y7 F9 G11 L24 S26 S28 F45 L51 P54 A55 Y58 W59 I65 K69 R75 V76 H79 N80 L83 Q5Y7D3 SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 4ozi B 3.20 BS02 CA B 1 E96 S179 Q181 E94 S169 Q171 Q5Y7D3 SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 4ozi C 3.20 BS01 III I 1 Y9 Y22 R52 F54 F58 N62 V65 L66 H68 N69 S72 L73 R76 Y9 Y23 R53 F54 F58 N62 V65 L66 H68 N69 S72 L73 R76 P01909 IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPE 4ozi D 3.20 BS01 III I 1 Y9 F11 L26 S30 F47 L53 P56 A57 Y60 W61 I67 K71 A74 R77 V78 H81 N82 L85 Y7 F9 L24 S28 F45 L51 P54 A55 Y58 W59 I65 K69 A72 R75 V76 H79 N80 L83 Q5Y7D3 SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 4ozi D 3.20 BS02 CA D 1 E96 S179 L180 Q181 E94 S170 L171 Q172 Q5Y7D3 SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTISPSHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRA 4ozi G 3.20 BS01 III J 1 N36 D108 G112A N28 D90 G96 KTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGDGGSFSGGYNKLIFGAGTRLAVHPYIQNPDPAVYQLRDSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP 4ozi H 3.20 BS01 III J 1 T37 V108 T30 V97 MVVSQHPSWVICKSGTSVKIECRSLDFQATTMFWYRQFPKQSLMLMATSNEGSKATYEQGVEKDKFLINHASLTLSTLTVTSAHPEDSSFYICSAGVGGQETQYFGPGTRLLVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 4p3e B 3.50 BS01 NUC A 1 F15 I16 C17 Y19 Y22 T28 I29 R33 R34 P36 I37 K66 M67 Y68 S69 R70 R74 R81 R101 F3 I4 C5 Y7 Y10 T16 I17 R21 R22 P24 I25 K54 M55 Y56 S57 R58 R62 R69 R89 P09132 24700861 DRFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNVFLEKNKMYSREWNRDVQYRGRVRVQLKQEDGSLCLVQFPSRKSVMLYAAEMIPKLKT 4p3e C 3.50 BS01 NUC A 1 Q73 R74 R76 Y78 S80 R81 R82 Q83 R84 R85 R87 K88 T89 R114 R125 R142 K143 F145 H146 S149 R150 K153 K156 Q24 R25 R27 Y29 S31 R32 R33 Q34 R35 R36 R38 K39 T40 R49 R60 R77 K78 F80 H81 S84 R85 K88 K91 Q9UHB9 24700861 LSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNDLLTDNRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIG 4p6w A 1.95 BS01 III B 1 I572 V575 K579 L589 D590 Q592 M593 L596 Q597 M752 E755 I756 N759 I47 V50 K54 L64 D65 Q67 M68 L71 Q72 M227 E230 I231 N234 P04150 PQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQELFDEIRMTYIKELGAAIVAREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6w A 1.95 BS02 MOF A 1 M560 L563 N564 G567 Q570 W600 M601 M604 R611 F623 I629 M639 Q642 C643 M646 Y735 C736 T739 I747 F749 M35 L38 N39 G42 Q45 W75 M76 M79 R86 F98 I104 M114 Q117 C118 M121 Y210 C211 T214 I222 F224 P04150 PQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQELFDEIRMTYIKELGAAIVAREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x A 2.50 BS01 III B 1 V575 K579 R585 L589 M593 L596 Q597 M752 E755 V50 K54 R60 L64 M68 L71 Q72 M227 E230 P04150 PQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x A 2.50 BS02 HCY A 1 L563 N564 G567 Q570 M601 M604 R611 F623 Q642 Y735 C736 T739 I747 L38 N39 G42 Q45 M76 M79 R86 F98 Q117 Y210 C211 T214 I222 P04150 PQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x C 2.50 BS01 III D 1 V575 K579 R585 L589 D590 M593 L596 Q597 M752 E755 I756 N759 V53 K57 R63 L67 D68 M71 L74 Q75 M230 E233 I234 N237 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x C 2.50 BS02 HCY C 1 L563 N564 Q570 W600 M601 M604 R611 F623 Q642 Y735 C736 T739 I747 L41 N42 Q48 W78 M79 M82 R89 F101 Q120 Y213 C214 T217 I225 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x E 2.50 BS01 III F 1 V575 K579 R585 L589 Q592 M593 L596 Q597 M752 E755 N759 V53 K57 R63 L67 Q70 M71 L74 Q75 M230 E233 N237 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x E 2.50 BS02 HCY E 1 L563 N564 G567 Q570 M601 M604 R611 F623 Q642 Y735 C736 T739 I747 L41 N42 G45 Q48 M79 M82 R89 F101 Q120 Y213 C214 T217 I225 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x G 2.50 BS01 III H 1 V575 K576 K579 R585 Q592 M593 L596 Q597 M752 E755 N759 V53 K54 K57 R63 Q70 M71 L74 Q75 M230 E233 N237 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ 4p6x G 2.50 BS02 HCY G 1 L563 N564 G567 Q570 M601 M604 R611 F623 Q642 Y735 C736 T739 I747 L41 N42 G45 Q48 M79 M82 R89 F101 Q120 Y213 C214 T217 I225 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ 4p6x I 2.50 BS01 III J 1 V575 K576 K579 R585 Q592 M593 L596 Q597 M752 E755 N759 V53 K54 K57 R63 Q70 M71 L74 Q75 M230 E233 N237 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x I 2.50 BS02 HCY I 1 M560 L563 N564 Q570 M601 M604 L608 R611 F623 Q642 Y735 C736 T739 I747 M38 L41 N42 Q48 M79 M82 L86 R89 F101 Q120 Y213 C214 T217 I225 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x K 2.50 BS01 III L 1 V575 K579 R585 L589 D590 M593 L596 M752 E755 I756 N759 V53 K57 R63 L67 D68 M71 L74 M230 E233 I234 N237 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4p6x K 2.50 BS02 HCY K 1 M560 L563 N564 Q570 M601 M604 R611 F623 Q642 Y735 C736 T739 I747 M38 L41 N42 Q48 M79 M82 R89 F101 Q120 Y213 C214 T217 I225 P04150 ATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTIPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 4pr5 A 1.80 BS01 III C 1 M5 Y7 Y59 R62 N63 I66 F67 T69 N70 T73 Y74 E76 S77 N80 L81 Y84 I95 R97 Y99 S116 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 M5 Y7 Y59 R62 N63 I66 F67 T69 N70 T73 Y74 E76 S77 N80 L81 Y84 I95 R97 Y99 S116 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 P30685 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 4pra A 1.85 BS01 III C 1 M5 Y7 Y9 Y59 R62 N63 I66 F67 T69 N70 Y74 E76 S77 N80 L81 Y84 I95 R97 Y99 S116 Y123 T143 K146 W147 A150 Q155 L156 Y159 W167 Y171 M5 Y7 Y9 Y59 R62 N63 I66 F67 T69 N70 Y74 E76 S77 N80 L81 Y84 I95 R97 Y99 S116 Y123 T143 K146 W147 A150 Q155 L156 Y159 W167 Y171 C5MK56 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 4prb A 1.75 BS01 III C 1 Y7 Y59 R62 N63 I66 F67 N70 T73 Y74 S77 N80 L81 Y84 R97 Y99 S116 T143 K146 W147 Q155 R156 Y159 W167 Y171 Y7 Y59 R62 N63 I66 F67 N70 T73 Y74 S77 N80 L81 Y84 R97 Y99 S116 T143 K146 W147 Q155 R156 Y159 W167 Y171 C5MK56 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQRRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 4prd A 1.75 BS01 III C 1 Y7 Y59 R62 N63 I66 F67 T73 Y74 S77 N80 L81 Y84 R97 Y99 S116 T143 K146 W147 Q155 R156 Y159 W167 Y171 Y7 Y59 R62 N63 I66 F67 T73 Y74 S77 N80 L81 Y84 R97 Y99 S116 T143 K146 W147 Q155 R156 Y159 W167 Y171 C5MK56 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQRRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 4pre A 1.65 BS01 III C 1 Y7 Y9 Y59 R62 N63 I66 F67 Y74 E76 S77 N80 L81 Y84 R97 Y99 S116 Y123 T143 K146 W147 A150 Q155 R156 Y159 W167 Y171 Y7 Y9 Y59 R62 N63 I66 F67 Y74 E76 S77 N80 L81 Y84 R97 Y99 S116 Y123 T143 K146 W147 A150 Q155 R156 Y159 W167 Y171 C5MK56 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQRRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 4pri A 2.40 BS01 III C 1 M5 Y7 Y59 R62 N63 I66 F67 N70 Y74 E76 S77 N80 L81 Y84 I95 R97 Y99 S116 T143 K146 W147 A150 V152 Q155 R156 Y159 W167 Y171 M5 Y7 Y59 R62 N63 I66 F67 N70 Y74 E76 S77 N80 L81 Y84 I95 R97 Y99 S116 T143 K146 W147 A150 V152 Q155 R156 Y159 W167 Y171 C5MK56 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQRRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 4pri D 2.40 BS01 III C 1 R31 L109 G110 T111 S112 G113 S114 R31 L93 G94 T95 S96 G97 S98 EDQVTQSPEALRLQEGESSSLNCSYTVSGLRGLFWYRQDPGKGPEFLFTLYSAGEEKEKERLKATLTKKESFLHITAPKPEDSATYLCAVQDLGTSGSRLTFGEGTQLTVNPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 4pri E 2.40 BS01 III C 1 D29 L30 Y40 Q55 Y57 S107 A108 R109 D28 L29 Y32 Q47 Y49 S93 A94 R95 SGVTQTPKHLITATGQRVTLRCSPRSGDLSVYWYQQSLDQGLQFLIQYYNGEERAKGNILERFSAQQFPDLHSELNLSSLELGDSALYFCASSARSGELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 4prn A 1.65 BS01 III C 1 M5 Y7 Y59 R62 N63 I66 F67 N70 T73 Y74 E76 S77 N80 L81 Y84 I95 R97 Y99 S116 Y123 T143 K146 W147 A150 V152 Q155 Y159 W167 Y171 M5 Y7 Y59 R62 N63 I66 F67 N70 T73 Y74 E76 S77 N80 L81 Y84 I95 R97 Y99 S116 Y123 T143 K146 W147 A150 V152 Q155 Y159 W167 Y171 P30685 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 4prp A 2.50 BS01 III C 1 Y7 R62 N63 I66 F67 N70 T73 Y74 E76 S77 N80 Y84 I95 R97 Y99 S116 Y123 T143 K146 W147 A150 V152 Q155 Y159 W167 Y171 Y7 R62 N63 I66 F67 N70 T73 Y74 E76 S77 N80 Y84 I95 R97 Y99 S116 Y123 T143 K146 W147 A150 V152 Q155 Y159 W167 Y171 C5MK56 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAPWIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 4prp D 2.50 BS01 III C 1 R31 L109 G110 T111 S112 G113 S114 R29 L91 G92 T93 S94 G95 S96 QVTQSPEALRLQEGESSSLNCSYTVSGLRGLFWYRQDPGKGPEFLFTLYSAGEEKEKERLKATLTKKESFLHITAPKPEDSATYLCAVQDLGTSGSRLTFGEGTQLTVNPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 4prp E 2.50 BS01 III C 1 D29 L30 S31 Y40 Q55 Y57 S107 A108 R109 D29 L30 S31 Y33 Q48 Y50 S94 A95 R96 DSGVTQTPKHLITATGQRVTLRCSPRSGDLSVYWYQQSLDQGLQFLIQYYNGEERAKGNILERFSAQQFPDLHSELNLSSLELGDSALYFCASSARSGELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 4pwy A 1.90 BS01 SAH A 1 W128 E131 G154 G156 D178 G179 N180 L210 R211 W212 D213 A231 D232 F235 L236 Y239 W56 E59 G82 G84 D106 G107 N108 L138 R139 W140 D141 A159 D160 F163 L164 Y167 2.1.1.60 Q7Z624 GSVRRFESFNLFSVTEGAWVQYTSIFCPEYSISLRHSLNVEDVLTSFDNTGNVCIWPSEEVLAYYCLKHNNIFRALAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVQDIITRNQKAGVFKTQKISSCFLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLQPRGKAMVFAPRRGNTLNQFCNLAEKAGFCIQRHENYDEHISNFHSKLKKENPDIYEENLHYPLLLILTKH 4pzk A 1.50 BS01 SAH A 1 L79 T80 K81 F103 G104 R105 E106 T107 N108 G109 L123 R124 I125 M127 S133 L134 T139 L78 T79 K80 F102 G103 R104 E105 T106 N107 G108 L122 R123 I124 M126 S132 L133 T138 2.1.1.207 Q81YT5 GVHVVLYQPEIPANTGNIARTCAATGTELHLIRPLGFSTDDKMLKRAGLDYWQHVKITYYDSIEEFYEKNKDGEFFYLTKYGEKAHTAFDYSKREKDYYFVFGRETNGLPANVIEENFDHCLRIPMTDKVRSLNLSNTAAILIYEAFRQQNYPGLDLEI 4pzk B 1.50 BS01 SAH B 1 L79 T80 K81 F103 G104 R105 E106 T107 G109 L123 R124 I125 M127 R132 S133 L134 T139 L78 T79 K80 F102 G103 R104 E105 T106 G108 L122 R123 I124 M126 R131 S132 L133 T138 2.1.1.207 Q81YT5 GVHVVLYQPEIPANTGNIARTCAATGTELHLIRPLGFSTDDKMLKRAGLDYWQHVKITYYDSIEEFYEKNKDGEFFYLTKYGEKAHTAFDYSKREKDYYFVFGRETNGLPANVIEENFDHCLRIPMTDKVRSLNLSNTAAILIYEAFRQQNYPGLDLEI