3vu3 A 2.85 BS01 HEM A 1 R125 H128 R165 G184 V199 G200 N201 F206 F214 H275 F391 L407 R411 S414 Y415 T418 Q419 R99 H102 R139 G158 V173 G174 N175 F180 F188 H249 F365 L381 R385 S388 Y389 T392 Q393 1.11.1.6 P21179 DSLAPEDGSHRPAAEPTPPGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIELTDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALKAKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDANYYLMEAYKHLKPIALAGDARKFKATIKIADQGEEGIVEADSADGSFMDELLTLMAAHRVWSRIPKIDKIPA 3w1n A 2.40 BS02 IRO A 1 K43 S44 N67 M69 G70 L71 N127 C130 N132 N194 S195 K44 S45 N68 M70 G71 L72 N128 C131 N133 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w1q B 1.85 BS02 YRO B 1 K43 N67 M69 G70 L71 N127 S129 P131 N194 S195 K44 N68 M70 G71 L72 N128 S130 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w1r A 1.58 BS02 MRO A 1 K43 N67 M69 G70 L71 N127 P131 N194 S195 K44 N68 M70 G71 L72 N128 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3zbt A 1.92 BS01 FAD A 1 R77 L78 Y79 S80 C98 V99 R100 L102 Y104 G115 V116 C117 S118 T157 E301 Y303 R69 L70 Y71 S72 C90 V91 R92 L94 Y96 G107 V108 C109 S110 T149 E293 Y295 1.18.1.2 P21890 24200908 DVPVNLYRPNAPFIGKVISNEPLVKEGGIGIVQHIKFDLTGGNLKYIEGQAIGIIPPGVDKNGKPEKLRLYSIASTRHGDDVDDKTISLCVRQLEYKHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMRTYLWRMFKDAERAANPEYQFKGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAISREQKNPQGGRMYIQDRVAEHADELWQLIKNQKTHTYICGLRGMEEGIDAALSAAAAKEGVTWSDYQKDLKKAGRWHVETY 3zc3 A 2.30 BS01 FAD A 1 R77 L78 Y79 A80 C98 V99 R100 L102 Y104 P107 G115 V116 C117 S118 T157 Y303 R69 L70 Y71 A72 C90 V91 R92 L94 Y96 P99 G107 V108 C109 S110 T149 Y295 1.18.1.2 P21890 24200908 DVPVNLYRPNAPFIGKVISNEPLVKEGGIGIVQHIKFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLYAIASTRHGDDVDDKTISLCVRQLEYKHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMRTYLWRMFKDAERAANPEYQFKGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAISREQKNPQGGRMYIQDRVAEHADELWQLIKNEKTHTYICGLRGMEEGIDAALSAAAAKEGVTWSDYQKDLKKAGRWHVETY 3zc3 A 2.30 BS02 NAP A 1 R100 L102 T155 G156 T157 G192 V193 P194 S223 R224 R233 Y235 Q237 G262 L263 Y303 R92 L94 T147 G148 T149 G184 V185 P186 S215 R216 R225 Y227 Q229 G254 L255 Y295 1.18.1.2 P21890 24200908 DVPVNLYRPNAPFIGKVISNEPLVKEGGIGIVQHIKFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLYAIASTRHGDDVDDKTISLCVRQLEYKHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMRTYLWRMFKDAERAANPEYQFKGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAISREQKNPQGGRMYIQDRVAEHADELWQLIKNEKTHTYICGLRGMEEGIDAALSAAAAKEGVTWSDYQKDLKKAGRWHVETY 3zfj A BS01 ZN A 1 E63 H83 H86 H88 E24 H44 H47 H49 Q04KS8 SYIDGDQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQ 4bhq A 2.05 BS01 MG A 1 G154 T192 G61 T99 Q5SII9 24218553 AVPWSQYLAAFINQIPRAGGRLEVALRSVSARALSEEEAARLAQEGTYDGKRIRVEFALQGEALSREALVRFIRAFETSPRFGIEFQGASLDEGRGLYTFSARVGVTGG 4bj3 A 3.04 BS01 III D 1 N154 I156 Y157 H258 L286 N12 I14 Y15 H116 L144 P17301 23922814 LIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDWAALLEKA 4bj3 A 3.04 BS02 III E 1 S153 N154 S155 Q215 D219 L220 T221 H258 S11 N12 S13 Q73 D77 L78 T79 H116 P17301 23922814 LIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDWAALLEKA 4bj3 A 3.04 BS03 MG A 1 S153 S155 T221 E256 S11 S13 T79 E114 P17301 23922814 LIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDWAALLEKA 4bj3 B 3.04 BS02 III E 1 N154 I156 Y157 N11 I13 Y14 P17301 23922814 IDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDWAALL 4bj3 B 3.04 BS03 MG B 1 S153 S155 T221 S10 S12 T78 P17301 23922814 IDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDWAALL 4bj8 A 2.40 BS01 BTN A 1 N14 L16 S18 Y33 T35 S39 W70 S74 S76 W78 W96 L98 D117 N11 L13 S15 Y30 T32 S36 W67 S71 S73 W75 W93 L95 D114 E7F650 24204770 SSCNVTGVWRNELGSTLRVKAEGSEVRGVYQTAVESTRGAAGHHRSARIIGMVSDGTQPTVSFSVLWEKGSCSAWVGQCFILDDGAQVLKTFWMLRSVADNLASAWGSTRMGEDIFFKT 4bj8 B 2.40 BS01 BTN B 1 N14 L16 S18 Y33 T35 V37 S39 A43 W70 S74 S76 W78 W96 L98 D117 N10 L12 S14 Y29 T31 V33 S35 A39 W66 S70 S72 W74 W92 L94 D113 E7F650 24204770 SCNVTGVWRNELGSTLRVKAEGSEVRGVYQTAVESTRGAAGHHRSARIIGMVSDGTQPTVSFSVLWEKGSCSAWVGQCFILDDGAQVLKTFWMLRSVADNLASAWGSTRMGEDIFFKT 4bmj A 2.75 BS01 ZN A 1 C10 C13 H29 H33 C7 C10 H26 H30 Q86VP1 MDVHKKCPLCELMFPPNYDQSKFEEHVESHWKVCPMCSEQFPPDYDQQVFERHVQTHFDQNV 4bpr A 2.00 BS01 FAD A 1 R77 L78 F79 S80 C98 V99 R100 L102 Y104 K105 P107 G115 V116 C117 S118 T157 E301 Y303 R69 L70 F71 S72 C90 V91 R92 L94 Y96 K97 P99 G103 V104 C105 S106 T145 E289 Y291 1.18.1.2 P21890 24200908 DVPVNLYRPNAPFIGKVISNEPLVKEGGIGIVQHIKFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLFSIASTRHGDDVDDKTISLCVRQLEYKHPTVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMRTYLWRMFKDAERAANPEYQFKGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAISREQKNPQGGRMYIQDRVAEHADQLWQLIKNQKTHTYICGLRGMEEGIDAALSAAAAKEGVTWSDYQKDLKKAGRWHVETY 4byi A 2.60 BS01 FH3 A 1 R137 L139 G140 V147 A160 E211 Y212 A213 P214 G216 T217 L263 R12 L14 G15 V22 A35 E86 Y87 A88 P89 G91 T92 L138 2.7.11.1 O14965 24195668 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 4byj A 2.75 BS01 FH5 A 1 L139 G142 V147 A160 K162 L194 L210 E211 Y212 A213 P214 G216 L263 L14 G17 V22 A35 K37 L69 L85 E86 Y87 A88 P89 G91 L138 2.7.11.1 O14965 24195668 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSS 4byq L 4.30 BS01 NUC N 1 K2 H3 K5 R6 Y7 R8 A35 K36 F37 T40 E42 H44 K46 P133 R134 D166 K167 T168 H172 A173 P174 S211 Y213 T215 T216 T217 M218 G219 S221 K1 H2 K4 R5 Y6 R7 A34 K35 F36 T39 E41 H43 K45 P130 R131 D163 K164 T165 H169 A170 P171 S208 Y210 T212 T213 T214 M215 G216 S218 24200810 KHGKRYRALLEKVDPNKIYTIDEAAHLVKELATAKFDETVEVHAKLGIDPRRSDQNVRGTVSLPHGLGKQVRVLAIAKGEKIKEAEEAGADYVGGEEIIQKILDGWMDFDAVVATPDVGAVGSKGRILGPRGLLPNPKAGTVGFNIGEIIREIKAGRIEFRNDKTGAIHAPVGKASFPPEKLADNIRAFIRALEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS 4byx V 6.60 BS01 NUC W 1 V535 Y536 G537 K538 T539 I540 H541 V524 Y525 G526 K527 T528 I529 H530 O26359 24200810 KDLRSPICCILGHVDTGKTKLLDKIRQTNVQGGEAGGITQQIGATYFPIDAIKAKTKVMAEYEKQTFDVPGLLVIDTPGHESFSNLRSRGSSLCNIAILVIDIMHGLEQQTIESIKLLRDRKAPFVVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSRYSKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLLWLLLELTQKRMSKQLMYLSHVEATILEVKVVEGFGTTIDVILSNGYLREGDRIVLCGMNGPIVTNIRALLTPQPLRELRLKSEYVHHKEVKAALGVKIAANDLEKAVSGSRLLVVGPEDDEDELMDDVMDAGVVVKADTLGSLEAVVKILRDMYVPIKVADIGDVSRRDVVNAGIALQEDRVYGAIIAFNVKVIPSAAQELKNSDIKLFQGNVIYRLMEEYEEWVRGIEEEKKKKWMEAIIKPASIRLIPKLVFRQSKPAIGGVEVLTGVIRQGYPLMNDDGETVGTVESMQDKGENLKSASRGQKVAMAIKDAVYGKTIHEGDTLYVDIPENHYHILLTDEELDLMDKIAEIKRKKNP 4c1k A 2.15 BS01 CO3 A 1 R115 K136 R166 R115 K136 R166 2.5.1.54 Q8U0A9 MKYSKEYKEKTVVKINDVKFGEGFTIIAGPCSIESRDQIMKVAEFLAEVGIKVLRGGAFKPRTSPYSFQGYGEKALRWMREAADEYGLVTVTEVMDTRHVELVAKYSDILQIGARNSQNFELLKEVGKVENPVLLKRGMGNTIQELLYSAEYIMAQGNENVILCERGIRTFETATRFTLDISAVPVVKELSHLPIIVDPSHPAGRRSLVIPLAKAAYAIGADGIMVEVHPEPEKALSDSQQQLTFDDFLQLLKELEALGWKG 4c1k A 2.15 BS02 PEP A 1 R55 K60 P61 Q111 G113 A114 R115 K136 R166 H201 R55 K60 P61 Q111 G113 A114 R115 K136 R166 H201 2.5.1.54 Q8U0A9 MKYSKEYKEKTVVKINDVKFGEGFTIIAGPCSIESRDQIMKVAEFLAEVGIKVLRGGAFKPRTSPYSFQGYGEKALRWMREAADEYGLVTVTEVMDTRHVELVAKYSDILQIGARNSQNFELLKEVGKVENPVLLKRGMGNTIQELLYSAEYIMAQGNENVILCERGIRTFETATRFTLDISAVPVVKELSHLPIIVDPSHPAGRRSLVIPLAKAAYAIGADGIMVEVHPEPEKALSDSQQQLTFDDFLQLLKELEALGWKG 4c1k B 2.15 BS02 CO3 B 1 G113 A114 R115 K136 R166 G113 A114 R115 K136 R166 2.5.1.54 Q8U0A9 MKYSKEYKEKTVVKINDVKFGEGFTIIAGPCSIESRDQIMKVAEFLAEVGIKVLRGGAFKPRTSPYSFQGYGEKALRWMREAADEYGLVTVTEVMDTRHVELVAKYSDILQIGARNSQNFELLKEVGKVENPVLLKRGMGNTIQELLYSAEYIMAQGNENVILCERGIRTFETATRFTLDISAVPVVKELSHLPIIVDPSHPAGRRSLVIPLAKAAYAIGADGIMVEVHPEPEKALSDSQQQLTFDDFLQLLKELEALGWKG 4c1k C 2.15 BS01 PEP C 1 R55 K60 E93 Q111 G113 A114 R115 K136 R166 H201 R55 K60 E93 Q111 G113 A114 R115 K136 R166 H201 2.5.1.54 Q8U0A9 MKYSKEYKEKTVVKINDVKFGEGFTIIAGPCSIESRDQIMKVAEFLAEVGIKVLRGGAFKPRTSPYSFQGYGEKALRWMREAADEYGLVTVTEVMDTRHVELVAKYSDILQIGARNSQNFELLKEVGKVENPVLLKRGMGNTIQELLYSAEYIMAQGNENVILCERGIRTFETATRFTLDISAVPVVKELSHLPIIVDPSHPAGRRSLVIPLAKAAYAIGADGIMVEVHPEPEKALSDSQQQLTFDDFLQLLKELEALGWKG 4c1k C 2.15 BS02 CO3 C 1 G113 A114 K136 R166 G113 A114 K136 R166 2.5.1.54 Q8U0A9 MKYSKEYKEKTVVKINDVKFGEGFTIIAGPCSIESRDQIMKVAEFLAEVGIKVLRGGAFKPRTSPYSFQGYGEKALRWMREAADEYGLVTVTEVMDTRHVELVAKYSDILQIGARNSQNFELLKEVGKVENPVLLKRGMGNTIQELLYSAEYIMAQGNENVILCERGIRTFETATRFTLDISAVPVVKELSHLPIIVDPSHPAGRRSLVIPLAKAAYAIGADGIMVEVHPEPEKALSDSQQQLTFDDFLQLLKELEALGWKG 4c1k D 2.15 BS01 CO3 D 1 A114 R115 K136 R166 H201 A114 R115 K136 R166 H201 2.5.1.54 Q8U0A9 MKYSKEYKEKTVVKINDVKFGEGFTIIAGPCSIESRDQIMKVAEFLAEVGIKVLRGGAFKPRTSPYSFQGYGEKALRWMREAADEYGLVTVTEVMDTRHVELVAKYSDILQIGARNSQNFELLKEVGKVENPVLLKRGMGNTIQELLYSAEYIMAQGNENVILCERGIRTFETATRFTLDISAVPVVKELSHLPIIVDPSHPAGRRSLVIPLAKAAYAIGADGIMVEVHPEPEKALSDSQQQLTFDDFLQLLKELEALGWKG 4c78 A 2.00 BS01 III C 1 R158 E177 F180 H248 V292 F294 G295 E296 L298 V324 E325 R37 E44 F47 H115 V159 F161 G162 E163 L165 V191 E192 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 4c78 A 2.00 BS02 BVB A 1 R139 M311 D313 R335 R18 M178 D180 R202 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 4c7b A 2.20 BS01 III B 1 F180 I291 V292 F293 F294 G295 E296 P297 L298 P326 F48 I159 V160 F161 F162 G163 E164 P165 L166 P194 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGK 4c7b A 2.20 BS03 BVB A 1 A146 F157 L173 I179 F180 L195 N229 I230 D231 A25 F36 L41 I47 F48 L63 N97 I98 D99 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGK 4c7o A 2.60 BS01 NUC E 1 E277 K278 E274 K275 P0AGD7 24211265 NLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAVVLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILG 4c7o A 2.60 BS02 ALF A 1 Q109 G110 K113 D138 R141 T191 G193 Q106 G107 K110 D135 R138 T188 G190 P0AGD7 24211265 NLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAVVLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILG 4c7o A 2.60 BS03 GDP A 1 G110 A111 G112 K113 T114 T115 K119 R141 Q147 K249 D251 G274 V275 G276 E277 G107 A108 G109 K110 T111 T112 K116 R138 Q144 K246 D248 G271 V272 G273 E274 P0AGD7 24211265 NLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAVVLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILG 4c7o A 2.60 BS04 GDP B 1 Q109 R141 L195 Q106 R138 L192 P0AGD7 24211265 NLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAVVLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILG 4c7o B 2.60 BS01 NUC E 1 F138 I158 A159 Q160 H161 G163 D165 S168 F171 D172 Q175 A176 A179 R180 A190 G191 H198 L199 E201 E202 K205 R208 V209 K212 F109 I129 A130 Q131 H132 G134 D136 S139 F142 D143 Q146 A147 A150 R151 A161 G162 H169 L170 E172 E173 K176 R179 V180 K183 P10121 24211265 DDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFA 4c7o B 2.60 BS03 ALF B 1 N108 G109 K112 D136 R139 G191 N79 G80 K83 D107 R110 G162 P10121 24211265 DDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFA 4c7o B 2.60 BS04 MG B 1 T113 D188 T84 D159 P10121 24211265 DDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFA 4c7o B 2.60 BS05 GDP B 1 G109 V110 G111 K112 T113 T114 Q145 K253 D255 G278 V279 G280 E281 G80 V81 G82 K83 T84 T85 Q116 K224 D226 G249 V250 G251 E252 P10121 24211265 DDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFA 4c7o C 2.60 BS01 ALF C 1 Q109 G110 K113 R141 G193 Q108 G109 K112 R140 G192 P0AGD7 24211265 FDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAVVLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFFPSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILGMG 4c7o D 2.60 BS04 GDP D 1 F138 A190 G191 L199 E202 F113 A165 G166 L174 E177 P10121 24211265 GKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARE 4ce9 A 2.10 BS02 O3N B 1 Q95 E96 Y99 T125 A128 A129 Q39 E40 Y43 T69 A72 A73 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4ce9 B 2.10 BS01 O3N A 1 Q95 E96 Y99 T125 A129 Q39 E40 Y43 T69 A73 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4cef A 1.70 BS02 D0T B 1 Q95 E96 Y99 A128 A129 Q39 E40 Y43 A72 A73 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4cer A 1.70 BS02 VL4 B 1 Q95 E96 Y99 A128 W132 Q39 E40 Y43 A72 W76 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4cf0 A 1.85 BS02 O5U B 1 Q95 E96 Y99 L102 T125 A129 W132 Q39 E40 Y43 L46 T69 A73 W76 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4cf0 B 1.85 BS01 O5U A 1 Q95 E96 Y99 L102 T125 W132 Q39 E40 Y43 L46 T69 W76 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4cf2 A 1.95 BS01 3GM A 1 Q168 E170 H171 K173 T174 M178 Q112 E114 H115 K117 T118 M122 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4cf2 B 1.95 BS02 3GM B 1 Q168 E170 H171 T174 M178 Q112 E114 H115 T118 M122 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4hh6 A 2.50 BS01 III Z 1 A9 R13 L15 H17 A20 L23 E24 R87 P88 Q89 A4 R8 L10 H12 A15 L18 E19 R82 P83 Q84 D3GUW1 ENSAALLRRLNHYCARALEGAASLCQTRAHAEITPEHWLLKLLEQGEGDLTVLGRRYDWDMDAIWQSLLGWLDNQPRSVRSRPQLAQSLNALLKQAWMVASLQGEEHIRSVHLLGALTENPHLVRCDGLWPLLTLSQSQLQRLSPLLDAQSDECPET 4i0i C 2.20 BS01 957 C 1 D38 G40 S41 V75 P76 Y77 T78 F114 I116 W121 I124 I132 Y204 I232 D234 G236 T237 D35 G37 S38 V72 P73 Y74 T75 F111 I113 W118 I121 I129 Y196 I224 D226 G228 T229 3.4.23.46 P56817 SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4i18 H 3.24 BS01 CA H 1 D76 S78 D73 S75 EVQLVESGGGLVQPGGSLRLSCAASGFNFSSSSMHWVRQAPGQGLEWVAYISPYYGSTSYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARSYGYVYWNAYSSGMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 4i18 B 3.24 BS01 CA B 1 D2 S94 Y95 D2 S94 Y95 SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQYYSYYYPFTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG 4i5y B 1.80 BS01 III A 1 V2 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28 A30 V2 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28 A30 P01317 FVNQHLCGSHLVEALYLVCGERGFFYTPKA 4i6b A 1.80 BS01 11G A 1 L88 K90 C96 A109 K111 V143 L159 E160 C162 F212 L18 K20 C26 A39 K41 V73 L89 E90 C92 F142 2.7.11.21 Q9NYY3 23794260 RIIVDPTTGKRYSRGKTLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVSKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINESMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGAESDIWALGCVMYTMLLGRPPFETTNLKETYRSIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFTQGFTPDRLSSSCCHTVPDFH 4i6f A 2.90 BS01 1C7 A 1 L88 C96 A109 V143 L159 E160 Y161 C162 R165 H169 F212 L18 C26 A39 V73 L89 E90 Y91 C92 R95 H99 F142 2.7.11.21 Q9NYY3 23794260 RIIVDPTTGKRYSRGKTLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVSKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINESMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGAESDIWALGCVMYTMLLGRPPFETTNLKETYRSIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFTQGFTPDRLSSSCCHTVPDFH 4i9c A 3.10 BS01 III C 1 Y66 F145 Y152 Y153 K155 Q183 L187 T190 D194 R223 Y226 N227 L230 S260 Q263 F266 Y300 E303 A334 D335 D338 Y64 F143 Y150 Y151 K153 Q181 L185 T188 D192 R221 Y224 N225 L228 S258 Q261 F264 Y298 E301 A332 D333 D336 3.1.-.- P71002 23526880 GVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEEDQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFNFFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDYARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQLMGRTLYNIGLCKNSQSQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKIDKAHEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFAIDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGV 4iae A 2.05 BS01 1DX A 1 M1 Y2 L4 V5 G39 W74 Y83 F97 L101 H105 V108 F112 L115 R116 P118 Y134 S136 R138 L141 M144 L148 M1 Y2 L4 V5 G39 W74 Y83 F97 L101 H105 V108 F112 L115 R116 P118 Y134 S136 R138 L141 M144 L148 4.6.1.2 23614626 MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYHLVGAASEVLGKPAEELLIAFGEYWVTYTSEEGYGELLASAGDSLPEFMENLDNLHARVGLSFPQLRPPAFECQHTSSKSMELHYQSTRAGLAPMVLGLLHGLGKRFQTKVEVTQTAFRETGEDHDIFSIKYE 4iam A 1.99 BS01 HEM A 1 M1 Y2 V5 W74 T78 Y83 L87 F97 L101 L104 H105 V108 L115 R116 P118 F120 Y134 S136 R138 L141 M144 V145 L148 M1 Y2 V5 W74 T78 Y83 L87 F97 L101 L104 H105 V108 L115 R116 P118 F120 Y134 S136 R138 L141 M144 V145 L148 4.6.1.2 Q8YUQ7 23614626 MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYHLVGAASEVLGKPAEELLIAFGEYWVTYTSEEGYGELLASAGDSLPEFMENLDNLHARVGLSFPQLRPPAFECQHTSSKSMELHYQSTRAGLAPMVLGLLHGLGKRFQTKVEVTQTAFRETGEDHDIFSIKYE 4iyb A 1.59 BS01 GAL A 1 D22 S24 G25 E26 I32 Y34 H37 N41 D22 S24 G25 E26 I32 Y34 H37 N41 F6KMV5 STQVSSGQTYKITNVKAGTVIDLSGEDNKSIIGYPYHSGKNQQWTFNWTGKAWTLRSASSGSYLGIEGTPADGTRLVAVNDPFEWHIWRDEANENAFRIFVPFTNYNLDLSGYGDTTPGTPVQLWWTWEGLHQTWTIDRP 4izx A 1.10 BS01 LAT A 1 D22 S24 G25 I32 Y34 H37 N41 D21 S23 G24 I31 Y33 H36 N40 F6KMV5 TQVSSGQTYKITNVKAGTVIDLSGEDNKSIIGYPYHSGKNQQWTFNWTGKAWTLRSASSGSYLGIEGTPADGTRLVAVNDPFEWHIWRDEANENAFRIFVPFTNYNLDLSGYGDTTPGTPVQLWWTWEGLHQTWTIDRP 4j2s A 1.40 BS01 MAG A 1 G25 E26 G24 E25 F6KMV5 TQVSSGQTYKITNVKAGTVIDLSGEDNKSIIGYPYHSGKNQQWTFNWTGKAWTLRSASSGSYLGIEGTPADGTRLVAVNDPFEWHIWRDEANENAFRIFVPFTNYNLDLSGYGDTTPGTPVQLWWTWEGLHQTWTIDRP 4jhq A 1.99 BS01 B6F A 1 N12 S16 Y33 T35 V37 T38 A39 T40 W70 F72 S75 T77 F79 W97 S101 K111 R114 N118 N11 S15 Y32 T34 V36 T37 A38 T39 W69 F71 S74 T76 F78 W96 S100 K110 R113 N117 P02701 RKCSLTGKWTNDLGSNMTIGAVNSKGEFTGTYTTAVTATSNEIKESPLHGTQNTINKRTQPTFGFTVNWKFSESTTVFTGQCFIDRNGKEVLKTMWLLRSSVNDIGDDWKATRVGINIFTRLRT 4jhq B 1.99 BS01 B6F B 1 N12 L14 S16 Y33 T35 A36 W70 F72 S73 S75 T77 F79 W97 L99 N118 N11 L13 S15 Y32 T34 A35 W69 F71 S72 S74 T76 F78 W96 L98 N117 P02701 RKCSLTGKWTNDLGSNMTIGAVNSKGEFTGTYTTAVTATSNEIKESPLHGTQNTINKRTQPTFGFTVNWKFSESTTVFTGQCFIDRNGKEVLKTMWLLRSSVNDIGDDWKATRVGINIFTRLR 4jqh A 2.30 BS01 1MF A 1 M1 Y2 L4 V5 M40 W74 Y83 L87 F97 L101 H105 V108 S111 F112 L115 R116 P118 Y134 S136 R138 L141 M144 L148 L152 M1 Y2 L4 V5 M40 W74 Y83 L87 F97 L101 H105 V108 S111 F112 L115 R116 P118 Y134 S136 R138 L141 M144 L148 L152 4.6.1.2 Q8YUQ7 24090476 MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYHLVGAASEVLGKPAEELLIAFGEYWVTYTSEEGYGELLASAGDSLPEFMENLDNLHARVGLSFPQLRPPAFECQHTSSKSMELHYQSTRAGLAPMVLGLLHGLGKRFQTKVEVTQTAFRETGEDHDIFSIKYE 4kmd A 1.70 BS01 III B 1 Y147 T154 F155 G158 D159 H160 V161 S162 W163 H164 N265 L266 S267 G268 V269 S270 A271 E376 L380 K398 Y120 T127 F128 G131 D132 H133 V134 S135 W136 H137 N238 L239 S240 G241 V242 S243 A244 E269 L273 K291 Q9UMX1 SLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNVGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDDLELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDLKLPKEYSWPEKKLKVSILPDVVFD 4lgt A 1.30 BS01 NUC E 1 K4 Q6 K7 A10 S16 R17 R18 E21 K37 L38 G39 D40 R41 L79 C80 T81 R82 N83 P85 E86 R88 R102 I104 G107 R108 L109 D110 V111 T113 G123 E124 A126 N127 M130 H131 P132 S133 E135 R138 Y140 G191 N193 R194 E195 V196 L210 R212 Y215 K4 Q6 K7 A10 S16 R17 R18 E21 K37 L38 G39 D40 R41 L79 C80 T81 R82 N83 P85 E86 R88 R102 I104 G107 R108 L109 D110 V111 T113 G123 E124 A126 N127 M130 H131 P132 S133 E135 R138 Y140 G191 N193 R194 E195 V196 L210 R212 Y215 5.4.99.22 P37765 24214967 MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEVTPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGVQLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYLRELVELPPETS 4lrl A 2.35 BS01 DGT A 1 K14 V15 F16 I35 N36 Q41 R44 F64 K15 V16 F17 I36 N37 Q42 R45 F65 Q836G9 AMTIPYKEQRLPIEKVFRDPVHNYIHVQHQVILDLINSAEVQRLRRIKQLGTSSFTFHGAEHSRFSHSLGVYEITRRICEIFQRNYSVERLGENGWNDDERLITLCAALLHDVGHGPYSHTFEHIFDTNHEAITVQIITSPETEVYQILNRVSADFPEKVASVITKQYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYKGGIAFAMNGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILDHLLHRAKELFENPEFDYDLQASLLVPFFKGDFTLQEYLKLDDGVLSTYFTQWMDVPDSILGDLAKRFLMRKPLKSATFTNEKESAATIAYLRELIEKVGFNPKYYTAINSSYDLPYDFYRPNKDRHRTQIELMQKDGSLVELATVSPLVAALAGQSQGDERFYFPKEMLDQDLFDETYREFSSYIHNGALVLKK 4lrl A 2.35 BS03 TTP B 1 T55 F56 Q241 H245 T56 F57 Q242 H246 Q836G9 AMTIPYKEQRLPIEKVFRDPVHNYIHVQHQVILDLINSAEVQRLRRIKQLGTSSFTFHGAEHSRFSHSLGVYEITRRICEIFQRNYSVERLGENGWNDDERLITLCAALLHDVGHGPYSHTFEHIFDTNHEAITVQIITSPETEVYQILNRVSADFPEKVASVITKQYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYKGGIAFAMNGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILDHLLHRAKELFENPEFDYDLQASLLVPFFKGDFTLQEYLKLDDGVLSTYFTQWMDVPDSILGDLAKRFLMRKPLKSATFTNEKESAATIAYLRELIEKVGFNPKYYTAINSSYDLPYDFYRPNKDRHRTQIELMQKDGSLVELATVSPLVAALAGQSQGDERFYFPKEMLDQDLFDETYREFSSYIHNGALVLKK 4lrl B 2.35 BS01 DGT A 1 F54 T55 R326 F53 T54 R325 Q836G9 TIPYKEQRLPIEKVFRDPVHNYIHVQHQVILDLINSAEVQRLRRIKQLGTSSFTFHGAEHSRFSHSLGVYEITRRICEIFQRNYSVERLGENGWNDDERLITLCAALLHDVGHGPYSHTFEHIFDTNHEAITVQIITSPETEVYQILNRVSADFPEKVASVITKQYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYKGGIAFAMNGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILDHLLHRAKELFENPEFDYDLQASLLVPFFKGDFTLQEYLKLDDGVLSTYFTQWMDVPDSILGDLAKRFLMRKPLKSATFTNEKESAATIAYLRELIEKVGFNPKYYTAINSSYDLPYDFYRPRHRTQIELMQKDGSLVELATVSPLVAALAGQSQGDERFYFPKEMLDDLFDETYREFSSYIHNGALVLKK 4lrl B 2.35 BS03 TTP B 1 V15 R17 V14 R16 Q836G9 TIPYKEQRLPIEKVFRDPVHNYIHVQHQVILDLINSAEVQRLRRIKQLGTSSFTFHGAEHSRFSHSLGVYEITRRICEIFQRNYSVERLGENGWNDDERLITLCAALLHDVGHGPYSHTFEHIFDTNHEAITVQIITSPETEVYQILNRVSADFPEKVASVITKQYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYKGGIAFAMNGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILDHLLHRAKELFENPEFDYDLQASLLVPFFKGDFTLQEYLKLDDGVLSTYFTQWMDVPDSILGDLAKRFLMRKPLKSATFTNEKESAATIAYLRELIEKVGFNPKYYTAINSSYDLPYDFYRPRHRTQIELMQKDGSLVELATVSPLVAALAGQSQGDERFYFPKEMLDDLFDETYREFSSYIHNGALVLKK 4lrl B 2.35 BS04 TTP D 1 R206 R209 R205 R208 Q836G9 TIPYKEQRLPIEKVFRDPVHNYIHVQHQVILDLINSAEVQRLRRIKQLGTSSFTFHGAEHSRFSHSLGVYEITRRICEIFQRNYSVERLGENGWNDDERLITLCAALLHDVGHGPYSHTFEHIFDTNHEAITVQIITSPETEVYQILNRVSADFPEKVASVITKQYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYKGGIAFAMNGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILDHLLHRAKELFENPEFDYDLQASLLVPFFKGDFTLQEYLKLDDGVLSTYFTQWMDVPDSILGDLAKRFLMRKPLKSATFTNEKESAATIAYLRELIEKVGFNPKYYTAINSSYDLPYDFYRPRHRTQIELMQKDGSLVELATVSPLVAALAGQSQGDERFYFPKEMLDDLFDETYREFSSYIHNGALVLKK 4lrl C 2.35 BS02 DGT D 1 F54 T55 V247 R326 K330 K422 F53 T54 V246 R325 K329 K421 Q836G9 TIPYKEQRLPIEKVFRDPVHNYIHVQHQVILDLINSAEVQRLRRIKQLGTSSFTFHGAEHSRFSHSLGVYEITRRICEIFQRNYSVERLGENGWNDDERLITLCAALLHDVGHGPYSHTFEHIFDTNHEAITVQIITSPETEVYQILNRVSADFPEKVASVITKQYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYKGGIAFAMNGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILDHLLHRAKELFENPEFDYDLQASLLVPFFKGDFTLQEYLKLDDGVLSTYFTQWMDVPDSILGDLAKRFLMRKPLKSATFTNEKESAATIAYLRELIEKVGFNPKYYTAINSSYDLPYDFYRPNKDRHRTQIELMQKDGSLVELATVSPLVAALAGQSQGDERFYFPKEMLDQGNKKHYDLFDETYREFSSYIHNGALVLKK 4lrl D 2.35 BS01 TTP B 1 R206 R209 N223 R206 R209 N223 Q836G9 MTIPYKEQRLPIEKVFRDPVHNYIHVQHQVILDLINSAEVQRLRRIKQLGTSSFTFHGAEHSRFSHSLGVYEITRRICEIFQRNYSVERLGENGWNDDERLITLCAALLHDVGHGPYSHTFEHIFDTNHEAITVQIITSPETEVYQILNRVSADFPEKVASVITKQYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYKGGIAFAMNGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILDHLLHRAKELFENPEFDYDLQASLLVPFFKGDFTLQEYLKLDDGVLSTYFTQWMDVPDSILGDLAKRFLMRKPLKSATFTNEKESAATIAYLRELIEKVGFNPKYYTAINSSYDLPYDFYRPNKDRHRTQIELMQKDGSLVELATVSPLVAALAGQSQGDERFYFPKEMLDLFDETYREFSSYI 4lwz A 2.55 BS01 GDP A 1 G21 V22 G23 K24 S25 N26 F36 N37 L38 S40 N124 K125 D127 L128 S154 A155 L156 G15 V16 G17 K18 S19 N20 F30 N31 L32 S34 N113 K114 D116 L117 S143 A144 L145 P62491 EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTARAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIY 4lx0 A 2.19 BS02 BEF A 1 S20 G21 K24 T43 G69 S14 G15 K18 T37 G63 P62491 EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVS 4lx0 C 2.19 BS02 BEF C 1 S20 G21 K24 S42 T43 G69 S14 G15 K18 S36 T37 G63 P62491 EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVS 4lx2 A 1.50 BS01 III B 1 N1522 D1524 V1527 R1528 T1532 I1535 N1536 S1570 L1588 T1589 N1590 F1591 D1592 E1595 Y1596 V1599 N53 D55 V58 R59 T63 I66 N67 S101 L119 T120 N121 F122 D123 E126 Y127 V130 Q9Y4I1 DFQGMLEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFISRV 4ly9 A 2.35 BS01 S6P A 1 G107 G108 T109 S110 E150 E153 S179 V180 G181 A184 S257 S258 R259 H351 K514 G105 G106 T107 S108 E148 E151 S177 V178 G179 A182 S255 S256 R257 H349 K493 Q14397 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEIFQEEGQSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDVRGFLIFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISITWPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEAVRSALA 4ly9 A 2.35 BS02 1YY A 1 H9 V10 I11 Y24 V28 P29 E32 G181 R215 H504 W517 A521 Q524 R525 H9 V10 I11 Y24 V28 P29 E32 G179 R213 H483 W496 A500 Q503 R504 Q14397 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEIFQEEGQSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDVRGFLIFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISITWPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEAVRSALA 4ly9 B 2.35 BS02 1YY B 1 H9 V10 I11 Y24 V28 P29 E32 G181 R215 H504 K514 W517 R518 A521 Q524 R525 H9 V10 I11 Y24 V28 P29 E32 G179 R213 H488 K498 W501 R502 A505 Q508 R509 Q14397 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEIFQEEGQSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDVRGFLIGQGPQFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISITWPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEAVRSALA 4m1u F 1.56 BS01 MBG F 1 D16 T18 W29 G59 D16 T18 W29 G59 Q7DJJ2 ADCAKGKIEFSKYNEDDTFTVKVDGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSGFAEVQFNND 4m1u F 1.56 BS02 MBG F 2 S53 S54 G61 S53 S54 G61 Q7DJJ2 ADCAKGKIEFSKYNEDDTFTVKVDGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSGFAEVQFNND 4mcv A 2.73 BS01 29K A 1 L273 V281 A293 K295 V323 G338 E339 Y340 M341 G344 A390 N391 L393 L18 V26 A38 K40 V68 G83 E84 Y85 M86 G89 A135 N136 L138 2.7.10.2 P00523 24171479 AKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVGEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 4mcv B 2.73 BS01 29K B 1 L273 A293 K295 V323 G338 E339 Y340 M341 G344 A390 N391 L393 L17 A37 K39 V66 G81 E82 Y83 M84 G87 A133 N134 L136 2.7.10.2 P00523 24171479 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVGEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 4mot A 1.75 BS01 2B7 A 1 I48 N51 A52 E55 V76 D78 R81 G82 M83 P84 I98 R140 T172 V174 I32 N35 A36 E39 V60 D62 R65 G66 M67 P68 I82 R107 T139 V141 5.99.1.- Q8DQB5 QVLEGLDAVRKRPGMYIGSTDGAGLHHLVWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTILHAVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLKKIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDEAIEFHYEN 4mwh A 2.09 BS01 ATP A 1 R48 G49 K50 Y51 S52 V54 V67 K69 I134 E153 V155 D195 K197 H199 N200 M202 I213 D214 R48 G49 K50 Y51 S52 V54 V67 K69 I134 E153 V155 D195 K197 H199 N200 M202 I213 D214 2.7.11.1 P15790 MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4mwv A 2.00 BS02 BCZ A 1 R119 E120 L135 D152 R153 W180 E229 E278 R294 R372 Y406 R37 E38 L53 D70 R71 W98 E147 E196 R212 R290 Y324 R4JGE3 24165891 RNFNNLTKGLCTINSWHIYGKDNAVRIGESSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKSRMSICISGPNNNASAVVWYNRRPVAEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPADTRIYYFKEGKILKWESLTGTAKHIEECSCYGERTGITCTCRDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPNDPNIGKCNDPYPGNNNNGVKGFSYLDGANTWLGRTISTASRSGYEMLKVPNALTDDRSKPIQGQTIVLNADWSGYSGSFMDYWAEGDCYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL 4mww A 1.90 BS02 G39 A 1 R119 E120 D152 R153 W180 I224 R226 E278 R372 Y406 R37 E38 D70 R71 W98 I142 R144 E196 R290 Y324 R4RZI6 24165891 RNFNNLTKGLCTINSWHIYGKDNAVRIGESSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKSRMSICISGPNNNASAVVWYNRRPVAEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPADTRIYYFKEGKILKWESLTGTAKHIEECSCYGERTGITCTCKDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPNDPNIGKCNDPYPGNNNNGVKGFSYLDGANTWLGRTISTASRSGYEMLKVPNALTDDRSKPIQGQTIVLNADWSGYSGSFMDYWAEGDCYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL 4mx0 A 2.10 BS02 BCZ A 1 R119 E120 L135 D152 R153 W180 R226 E229 A248 E278 E279 R372 Y406 R37 E38 L53 D70 R71 W98 R144 E147 A166 E196 E197 R290 Y324 R4RZI6 24165891 RNFNNLTKGLCTINSWHIYGKDNAVRIGESSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKSRMSICISGPNNNASAVVWYNRRPVAEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPADTRIYYFKEGKILKWESLTGTAKHIEECSCYGERTGITCTCKDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPNDPNIGKCNDPYPGNNNNGVKGFSYLDGANTWLGRTISTASRSGYEMLKVPNALTDDRSKPIQGQTIVLNADWSGYSGSFMDYWAEGDCYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL 4mz7 A 1.80 BS01 ZN A 1 H167 H206 D207 D311 H55 H94 D95 D193 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4mz7 A 1.80 BS02 DGT A 1 Q149 L150 R164 H215 D309 D311 K312 Y315 D319 R366 H370 Y374 Q375 Q37 L38 R52 H103 D191 D193 K194 Y197 D201 R248 H252 Y256 Q257 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4mz7 A 1.80 BS03 DGT A 2 V156 F157 I325 R372 H376 K377 V378 V44 F45 I207 R254 H258 K259 V260 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4mz7 A 1.80 BS05 DGT B 1 Y155 V156 P158 V378 R451 K455 Y43 V44 P46 V260 R333 K337 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4mz7 A 1.80 BS06 DTP B 1 V117 I118 N119 V5 I6 N7 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4mz7 B 1.80 BS06 DTP B 1 V156 F157 R372 H376 K377 V378 V55 F56 R266 H270 K271 V272 3.1.5.- Q9Y3Z3 NLYFQGSQIHVDTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4n07 A 1.87 BS01 2J9 A 1 K104 P105 F106 M107 S108 L239 S242 L247 K104 P105 F106 M107 S108 L239 S242 L247 P19491 24131202 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECG 4n07 B 1.87 BS04 ZN B 2 D156 R163 D155 R162 P19491 24131202 ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGEC 4n07 C 1.87 BS01 2J9 B 1 K104 P105 F106 M107 S108 S242 L247 K104 P105 F106 M107 S108 S242 L247 P19491 24131202 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECG 4n32 D 1.75 BS01 2F8 D 1 E285 N287 E293 K299 N307 D308 K313 E89 N91 E97 K103 N111 D112 K117 Q9UJ71 QGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSARFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYV 4n33 A 1.85 BS01 NAG A 1 E285 N287 E293 K299 N307 D308 P310 E88 N90 E96 K102 N110 D111 P113 Q9UJ71 GWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSARFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVP 4n35 C 1.85 BS01 NAG C 1 E285 N287 E293 K299 N307 D308 I313 E90 N92 E98 K104 N112 D113 I118 Q9UJ71 SQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSARFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDITFLFICKRPYVP 4n5t A 1.70 BS01 III B 1 M50 H51 G54 I57 M58 Y63 Q68 H69 V89 K90 P92 L95 Y96 M34 H35 G38 I41 M42 Y47 Q52 H53 V73 K74 P76 L79 Y80 Q7ZUW7 23946421 LPGEGTQVHPRAPLLQILKVAGAQEEVFTVKEVMHYLGQYIMMKQLYDKQRQHIVHCHDDPLGELLEVGSFSVKNPSPLYEMLKRNLVIL 4n7b A 2.20 BS01 F3S A 1 C14 G16 C98 T166 C196 Y197 A267 C14 G16 C98 T166 C196 Y197 A267 Q9BJX6 24188825 PNKILYLINPRGFCKGVSRAIETVEECLKLFKPPIYVKHKIVHNDIVCKKLEKEGAIFIEDLNDVPDGHILIYSAHGISPQIREIAKKKKLIEIDATCPLVNKVHVYVQMKAKENYDIILIGYKNHVEVIGTYNEAPHCTHIVENVNDVDKLNFPLNKKLFYVTQTTLSMDDCALIVQKLKNKFPHIETIPSGSICYATTNRQTALNKICTKCDLTIVVGSSSSSNAKKLVYSSQIRNVPAVLLNTVHDLDQQILKNVNKIALTSAASTPEQETQKFVNLLTNPPFNYTLQNFDGAHENVPKWKLPKNFLHMIKEREK 4n8y A 1.50 BS01 ADA A 1 H31 E69 R85 N87 R145 R166 Q168 Y189 N206 S210 E233 H9 E47 R63 N65 R123 R144 Q146 Y167 N184 S188 E211 A5E8D2 RDFRSADVHPADYPTVEAVKFMGKQLAAASGGKLGVKVFPNGALGSEKDTIEQLKIGALDMMRINSSPLNNFVPETVALCLPFVFRDTQHMRNVLDGPIGDEILAAMEPAGLVGLAYYDSGARSIYTVKAPVKSLADLKGLKIRVQQSDLWVGMIQSLGANPTPMPYGEVYTALKTGLVDAAENNWPSYESSRHFEAAKFYNITEHSLAPEVLVMSKKVWDTLSKEDQALVRKAAKDSVPVMRKLWDEREQASRKAVEAAGVQVVTVANKQEFVDAMKPVYQKFAGDEKLSSLVKRIQDT 4n8y A 1.50 BS02 GTR A 1 H31 E69 R85 N87 S142 R145 R166 Q168 Y189 N206 N207 S210 E233 H9 E47 R63 N65 S120 R123 R144 Q146 Y167 N184 N185 S188 E211 A5E8D2 RDFRSADVHPADYPTVEAVKFMGKQLAAASGGKLGVKVFPNGALGSEKDTIEQLKIGALDMMRINSSPLNNFVPETVALCLPFVFRDTQHMRNVLDGPIGDEILAAMEPAGLVGLAYYDSGARSIYTVKAPVKSLADLKGLKIRVQQSDLWVGMIQSLGANPTPMPYGEVYTALKTGLVDAAENNWPSYESSRHFEAAKFYNITEHSLAPEVLVMSKKVWDTLSKEDQALVRKAAKDSVPVMRKLWDEREQASRKAVEAAGVQVVTVANKQEFVDAMKPVYQKFAGDEKLSSLVKRIQDT 4ne7 A 2.50 BS02 ZN A 2 D210 D258 D208 D256 PTAYTPLDVAQAYQFPEGLDGQGQCIAIIELGGGYDEASLAQYFASLGVPAPQVVSVSVDGASNQPTGDPKGPDGEVELDIEVAGALAPGAKFAVYFAPDTTAGFLDAITTAIHDPTLKPSVVSISWSGPEDSWTSAAIAAMNRAFLDAAALGVTVLAAAGDSGSTGGEQDGLYHVHFPAASPYVLACGGTRLVASGGRIAQETVWNDGPDGGATGGGVSRIFPLPAWQEHANVPPSANPGASSGRGVPDLAGNADPATGYEVVIDGEATVIGGTSAVAPLFAALVARINQKLGKAVGYLNPTLYQLPADVFHDITEGNNDIANRAQIYQAGPGWDPCTGLGSPIGVRLLQALLPS 4ne7 A 2.50 BS03 ZN A 3 E171 D173 H177 E169 D171 H175 PTAYTPLDVAQAYQFPEGLDGQGQCIAIIELGGGYDEASLAQYFASLGVPAPQVVSVSVDGASNQPTGDPKGPDGEVELDIEVAGALAPGAKFAVYFAPDTTAGFLDAITTAIHDPTLKPSVVSISWSGPEDSWTSAAIAAMNRAFLDAAALGVTVLAAAGDSGSTGGEQDGLYHVHFPAASPYVLACGGTRLVASGGRIAQETVWNDGPDGGATGGGVSRIFPLPAWQEHANVPPSANPGASSGRGVPDLAGNADPATGYEVVIDGEATVIGGTSAVAPLFAALVARINQKLGKAVGYLNPTLYQLPADVFHDITEGNNDIANRAQIYQAGPGWDPCTGLGSPIGVRLLQALLPS 4ne7 A 2.50 BS04 ZN A 4 H116 D150 H114 D148 PTAYTPLDVAQAYQFPEGLDGQGQCIAIIELGGGYDEASLAQYFASLGVPAPQVVSVSVDGASNQPTGDPKGPDGEVELDIEVAGALAPGAKFAVYFAPDTTAGFLDAITTAIHDPTLKPSVVSISWSGPEDSWTSAAIAAMNRAFLDAAALGVTVLAAAGDSGSTGGEQDGLYHVHFPAASPYVLACGGTRLVASGGRIAQETVWNDGPDGGATGGGVSRIFPLPAWQEHANVPPSANPGASSGRGVPDLAGNADPATGYEVVIDGEATVIGGTSAVAPLFAALVARINQKLGKAVGYLNPTLYQLPADVFHDITEGNNDIANRAQIYQAGPGWDPCTGLGSPIGVRLLQALLPS 4neu A 2.57 BS01 MG A 1 S14 F17 L18 S9 F12 L13 2.7.11.1 Q13546 SLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA 4neu A 2.57 BS02 Q1A A 1 V31 I43 E63 M67 L70 V75 V76 M92 E93 Y94 M95 L145 A155 D156 L157 V26 I38 E58 M62 L65 V70 V71 M87 E88 Y89 M90 L140 A150 D151 L152 2.7.11.1 Q13546 SLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA 4nf0 A 1.85 BS01 LMR A 1 K43 S93 K96 R171 Q173 Y194 N211 N215 L236 Y238 K16 S66 K69 R144 Q146 Y167 N184 N188 L209 Y211 Q9HVH5 PVVIKFSHVVSDDTPKGKGALLFKKLAEERLPGKVKVEVYPNSTLFGDADEIEALRANKVQMLATSLSKFEPYTKQLQVFDLPFLFDDLEALKRFQKRDKSRELLRSMAKHGIYGLAYWNNGMKQLSATRELHRPDDAKGLVFRIQPSSVLEAQFAMLGATAKQLSYAETLKAMQAGSVQGTENTWSNLAGQKIDSVQPYITETNHGALSYMLITSSAFWTGIPYQTRTELESIVDEVTLVVNKEAEALNQKEREHLLAAGKSRLVSLSAEEHEAWRNAMKPLWKNYEAQI 4nf0 B 1.85 BS01 LMR B 1 V37 K43 S93 K96 R171 Q173 Y194 N211 N215 Y238 V10 K16 S53 K56 R131 Q133 Y154 N171 N175 Y198 Q9HVH5 PVVIKFSHVVSDDTPKGKGALLFVEVYPNSTLFGDADEIEALRANKVQMLATSLSKFEPYTKQLQVFDLPFLFDDLEALKRFQKRDKSRELLRSMAKHGIYGLAYWNNGMKQLSATRELHRPDDAKGLVFRIQPSSVLEAQFAMLGATAKQLSYAETLKAMQAGSVQGTENTWSNLAGQKIDSVQPYITETNHGALSYMLITSSAFWTGRTELESIVDEVTLVVNKEAEALNQKEREHLLAAGKSRLVSLSAEEHEAWRNAMKPLWKNYEAQI 4nhb A 1.90 BS01 G3P A 1 M36 K37 G93 T94 Q95 E107 R151 R171 P173 I175 F194 H238 M8 K9 G65 T66 Q67 E79 R123 R134 P136 I138 F157 H201 B8J100 TVIKMAGMKPEGEPETIGMHLFGKYLKELSNGKYEVQVFPNSQLGKEDAYIAATRKGIIQMCATGTQTSALHPAMAMLETPMLFDNLDHARRAMEGKTFDLINEGFTEKSGLRTLNAFPLGFRHFYSKKPMRMRVPNIPLYTNFAKECGISGQPMPFAEVPGALDQGVIDGGDSPLADIVSLKMYEITPEISLSGHILVIHSLYINDKFFKSLPEQDQKWIEEAAKRSADDVWAMVADGDEKAKATILANKGNIHEPSKELHEHLVNAGKRSWKLFYDTVPNAQAILDSADSYR 4nhb B 1.90 BS01 G3P B 1 K37 G93 T94 Q95 E107 R151 R172 P174 H239 K9 G65 T66 Q67 E79 R123 R143 P145 H210 B8J100 TVIKMAGMKPEGEPETIGMHLFGKYLKELSNGKYEVQVFPNSQLGKEDAYIAATRKGIIQMCATGTQTSALHPAMAMLETPMLFDNLDHARRAMEGKTFDLINEGFTEKSGLRTLNAFPLGFRHFYSKKPIKDVKDLEGMRMRVPNIPLYTNFAKECGISGQPMPFAEVPGALDQGVIDGGDSPLADIVSLKMYEITPEISLSGHILVIHSLYINDKFFKSLPEQDQKWIEEAAKRSADDVWAMVADGDEKAKATILANKGNIHEPSKELHEHLVNAGKRSWKLFYDTVPNAQAILDSADSYRESKAENLY 4nhw A 2.00 BS01 GSH A 1 S10 R11 Q33 A34 H35 T49 L62 I63 P64 E75 S76 S10 R11 Q33 A34 H35 T49 L62 I63 P64 E75 S76 2.5.1.18 M4MQ92 MLTIYGVYRSRASRNYWMAGELGLPFRSVPVVQAHRVADPLAADAPLNTKSPGFLAINPMGLIPAIEDDGLVLTESLANNLYLARKHGGPLAPADIREEGQIGNWTMWAATEVEPHAVKIVLAHTPEGRAEIAACARSLEKAFAVLETHLAERDYVVGDRFTVADLNLAEVFRYTMSQTDLFKRHPQVKAWLARCQSRPAFKAMMEERLKEPE 4nhw A 2.00 BS02 GSH B 1 T111 E112 T111 E112 2.5.1.18 M4MQ92 MLTIYGVYRSRASRNYWMAGELGLPFRSVPVVQAHRVADPLAADAPLNTKSPGFLAINPMGLIPAIEDDGLVLTESLANNLYLARKHGGPLAPADIREEGQIGNWTMWAATEVEPHAVKIVLAHTPEGRAEIAACARSLEKAFAVLETHLAERDYVVGDRFTVADLNLAEVFRYTMSQTDLFKRHPQVKAWLARCQSRPAFKAMMEERLKEPE 4nhw D 2.00 BS02 GSH D 1 S10 R11 Q33 T49 L62 I63 P64 E75 S76 S18 R19 Q41 T57 L70 I71 P72 E83 S84 2.5.1.18 M4MQ92 TENLYFQSMLTIYGVYRSRASRNYWMAGELGLPFRSVPVVQAHRVADPLAADAPLNTKSPGFLAINPMGLIPAIEDDGLVLTESLANNLYLARKHGGPLAPADIREEGQIGNWTMWAATEVEPHAVKIVLAHDNEIAACARSLEKAFAVLETHLAERDYVVGDRFTVADLNLAEVFRYTMSQTDLFKRHPQVKAWLARCQSRPAFKAMMEERLKEPE 4nhz A 1.90 BS01 GSH A 1 T28 N30 K33 F52 K58 K70 I71 E89 S90 T26 N28 K31 F50 K56 K68 I69 E87 S88 A5EI34 DLSSFPITKRWPAQHSDRIQLYSLPTPNGVKVSIMLEETGLPYEPHAIDFGKDHQKTPEFLSLNPNGKIPAIIDPNGPGDKPLGLFESGAILQYLAEKTGQFLPADPARRWQTLQWLHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLGVLEARLDGRQWIMDADYTIADIATLGWVRNLIGFYGARELVAFDELTHVPAWLERGLARPAVQRGLEIPKRP 4nhz B 1.90 BS01 GSH B 1 T28 N30 F52 K70 I71 P72 E89 S90 T38 N40 F62 K80 I81 P82 E99 S100 A5EI34 LGTENLYFQSMSDLSSFPITKRWPAQHSDRIQLYSLPTPNGVKVSIMLEETGLPYEPHAIDFGKDHQKTPEFLSLNPNGKIPAIIDPNGPGDKPLGLFESGAILQYLAEKTGQFLPADPARRWQTLQWLHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLGVLEARLDGRQWIMDADYTIADIATLGWVRNLIGFYGARELVAFDELTHVPAWLERGLARPAVQRGLEIPKRP 4nhz C 1.90 BS01 GSH C 1 T28 N30 F52 K58 G69 K70 I71 E89 S90 T27 N29 F51 K57 G68 K69 I70 E88 S89 A5EI34 SDLSSFPITKRWPAQHSDRIQLYSLPTPNGVKVSIMLEETGLPYEPHAIDFGKDHQKTPEFLSLNPNGKIPAIIDPNGPGDKPLGLFESGAILQYLAEKTGQFLPADPARRWQTLQWLHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLGVLEARLDGRQWIMDADYTIADIATLGWVRNLIGFYGARELVAFDELTHVPAWLERGLARPAVQRGLEIPKRP 4nhz D 1.90 BS01 GSH D 1 T29 N31 F53 Q58 K71 I72 P73 E90 S91 T26 N28 F50 Q55 K68 I69 P70 E87 S88 A5EI34 DLSSFPITKRWPAQHSDRIQLYSLPTPNGVKVSIMLEETGLPYEPHAIDFGKDHQKTPEFLSLNPNGKIPAIIDPNGPGDKPLGLFESGAILQYLAEKTGQFLPADPARRWQTLQWLHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLGVLEARLDGRQWIMDADYTIADIATLGWVRNLIGFYGARELVAFDELTHVPAWLERGLARPAVQRGLEIPKRP 4nhz G 1.90 BS01 GSH G 1 T28 N30 K33 F52 K58 G69 K70 I71 E89 S90 T25 N27 K30 F49 K55 G66 K67 I68 E86 S87 A5EI34 LSSFPITKRWPAQHSDRIQLYSLPTPNGVKVSIMLEETGLPYEPHAIDFGKDHQKTPEFLSLNPNGKIPAIIDPNGPGDKPLGLFESGAILQYLAEKTGQFLPADPARRWQTLQWLHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLGVLEARLDGRQWIMDADYTIADIATLGWVRNLIGFYGARELVAFDELTHVPAWLERGLARPAVQRGLEIPKRP 4nhz I 1.90 BS01 GSH I 1 T28 N30 F52 K70 I71 E89 S90 T26 N28 F50 K68 I69 E87 S88 A5EI34 DLSSFPITKRWPAQHSDRIQLYSLPTPNGVKVSIMLEETGLPYEPHAIDFGKDHQKTPEFLSLNPNGKIPAIIDPNGPGDKPLGLFESGAILQYLAEKTGQFLPADPARRWQTLQWLHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLGVLEARLDGRQWIMDADYTIADIATLGWVRNLIGFYGARELVAFDELTHVPAWLERGLARPAVQRGLEIPKRP 4nhz L 1.90 BS01 GSH L 1 T28 N30 F52 K70 I71 T27 N29 F51 K69 I70 A5EI34 SDLSSFPITKRWPAQHSDRIQLYSLPTPNGVKVSIMLEETGLPYEPHAIDFGKDHQKTPEFLSLNPNGKIPAIIDPNGPGDKPLGLFESGAILQYLAEKTGQFLPADPARRWQTLQWLHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLGVLEARLDGRQWIMDADYTIADIATLGWVRNLIGFYGARELVAFDELTHVPAWLERGLARPAVQRGLEIPKRP 4nhz M 1.90 BS01 GSH M 1 T28 N30 F52 Q57 K58 K70 I71 P72 E89 S90 T25 N27 F49 Q54 K55 K67 I68 P69 E86 S87 A5EI34 LSSFPITKRWPAQHSDRIQLYSLPTPNGVKVSIMLEETGLPYEPHAIDFGKDHQKTPEFLSLNPNGKIPAIIDPNGPGDKPLGLFESGAILQYLAEKTGQFLPADPARRWQTLQWLHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLGVLEARLDGRQWIMDADYTIADIATLGWVRNLIGFYGARELVAFDELTHVPAWLERGLARPAVQRGLEIPKRP 4nhz N 1.90 BS01 GSH N 1 T28 N30 K33 F52 K70 I71 P72 E89 S90 T26 N28 K31 F50 K68 I69 P70 E87 S88 A5EI34 DLSSFPITKRWPAQHSDRIQLYSLPTPNGVKVSIMLEETGLPYEPHAIDFGKDHQKTPEFLSLNPNGKIPAIIDPNGPGDKPLGLFESGAILQYLAEKTGQFLPADPARRWQTLQWLHFQMGGIGPMFGQLGFFHKFAGREYEDKRPLQRYVAESKRLLGVLEARLDGRQWIMDADYTIADIATLGWVRNLIGFYGARELVAFDELTHVPAWLERGLARPAVQRGLEIPKRP